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Sample records for volumes required complete

  1. Hanford analytical services quality assurance requirements documents. Volume 1: Administrative Requirements

    International Nuclear Information System (INIS)

    Hyatt, J.E.

    1997-01-01

    Hanford Analytical Services Quality Assurance Requirements Document (HASQARD) is issued by the Analytical Services, Program of the Waste Management Division, US Department of Energy (US DOE), Richland Operations Office (DOE-RL). The HASQARD establishes quality requirements in response to DOE Order 5700.6C (DOE 1991b). The HASQARD is designed to meet the needs of DOE-RL for maintaining a consistent level of quality for sampling and field and laboratory analytical services provided by contractor and commercial field and laboratory analytical operations. The HASQARD serves as the quality basis for all sampling and field/laboratory analytical services provided to DOE-RL through the Analytical Services Program of the Waste Management Division in support of Hanford Site environmental cleanup efforts. This includes work performed by contractor and commercial laboratories and covers radiological and nonradiological analyses. The HASQARD applies to field sampling, field analysis, and research and development activities that support work conducted under the Hanford Federal Facility Agreement and Consent Order Tri-Party Agreement and regulatory permit applications and applicable permit requirements described in subsections of this volume. The HASQARD applies to work done to support process chemistry analysis (e.g., ongoing site waste treatment and characterization operations) and research and development projects related to Hanford Site environmental cleanup activities. This ensures a uniform quality umbrella to analytical site activities predicated on the concepts contained in the HASQARD. Using HASQARD will ensure data of known quality and technical defensibility of the methods used to obtain that data. The HASQARD is made up of four volumes: Volume 1, Administrative Requirements; Volume 2, Sampling Technical Requirements; Volume 3, Field Analytical Technical Requirements; and Volume 4, Laboratory Technical Requirements. Volume 1 describes the administrative requirements

  2. Advanced light water reactor utility requirements document: Volume 1--ALWR policy and summary of top-tier requirements

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    The U.S. utilities are leading an industry wide effort to establish the technical foundation for the design of the Advanced Light Water Reactor (ALWR). This effort, the ALWR Program, is being managed for the U.S. electric utility industry by the Electric Power Research Institute (EPRI) and includes participation and sponsorship of several international utility companies and close cooperation with the U.S. Department of Energy (DOE). The cornerstone of the ALWR Program is a set of utility design requirements which are contained in the ALWR Requirements Document. The purpose of the Requirement Document is to present a clear, complete statement of utility desires for their next generation of nuclear plants. The Requirements Document covers the entire plant up to the grid interface. It therefore is the basis for an integrated plant design, i.e., nuclear steam supply system and balance of plant, and it emphasizes those areas which are most important to the objective of achieving an ALWR which is excellent with respect to safety, performance, constructibility, and economics. The document applies to both Pressurized Water Reactors (PWRs) and Boiling Water Reactors (BWRs). The Requirements Document is organized in three volumes. Volume 1 summarizes AlWR Program policy statements and top-tier requirements. The top-tier design requirements are categorized by major functions, including safety and investment protection, performance, and design process and constructibility. There is also a set of general design requirements, such as simplification and proven technology, which apply broadly to the ALWR design, and a set of economic goals for the ALWR program. The top-tier design requirements are described further in Volume 1 and are formally invoked as requirements in Volumes 2 and 3

  3. FMDP Reactor Alternative Summary Report: Volume 3 - partially complete LWR alternative

    International Nuclear Information System (INIS)

    Greene, S.R.; Fisher, S.E.; Bevard, B.B.

    1996-09-01

    The Department of Energy Office of Fissile Materials Disposition (DOE/MD) initiated a detailed analysis activity to evaluate each of ten plutonium disposition alternatives that survived an initial screening process. This document, Volume 3 of a four volume report summarizes the results of these analyses for the partially complete LWR (PCLWR) reactor based plutonium disposition alternative

  4. FMDP Reactor Alternative Summary Report: Volume 3 - partially complete LWR alternative

    Energy Technology Data Exchange (ETDEWEB)

    Greene, S.R.; Fisher, S.E.; Bevard, B.B. [and others

    1996-09-01

    The Department of Energy Office of Fissile Materials Disposition (DOE/MD) initiated a detailed analysis activity to evaluate each of ten plutonium disposition alternatives that survived an initial screening process. This document, Volume 3 of a four volume report summarizes the results of these analyses for the partially complete LWR (PCLWR) reactor based plutonium disposition alternative.

  5. Against Better Knowledge: The Magical Force of Amodal Volume Completion

    Directory of Open Access Journals (Sweden)

    Vebjørn Ekroll

    2013-12-01

    Full Text Available In a popular magic routine known as “multiplying billiard balls”, magicians fool their audience by using an empty shell that the audience believes to be a complete ball. Here, we present some observations suggesting that the spectators do not merely entertain the intellectual belief that the balls are all solid, but rather automatically and immediately perceive them as such. Our observations demonstrate the surprising potency and genuinely perceptual origin of amodal volume completion.

  6. NMDA receptors are not required for pattern completion during associative memory recall.

    Directory of Open Access Journals (Sweden)

    Bing Mei

    2011-04-01

    Full Text Available Pattern completion, the ability to retrieve complete memories initiated by subsets of external cues, has been a major focus of many computation models. A previously study reports that such pattern completion requires NMDA receptors in the hippocampus. However, such a claim was derived from a non-inducible gene knockout experiment in which the NMDA receptors were absent throughout all stages of memory processes as well as animal's adult life. This raises the critical question regarding whether the previously described results were truly resulting from the requirement of the NMDA receptors in retrieval. Here, we have examined the role of the NMDA receptors in pattern completion via inducible knockout of NMDA receptors limited to the memory retrieval stage. By using two independent mouse lines, we found that inducible knockout mice, lacking NMDA receptor in either forebrain or hippocampus CA1 region at the time of memory retrieval, exhibited normal recall of associative spatial reference memory regardless of whether retrievals took place under full-cue or partial-cue conditions. Moreover, systemic antagonism of NMDA receptor during retention tests also had no effect on full-cue or partial-cue recall of spatial water maze memories. Thus, both genetic and pharmacological experiments collectively demonstrate that pattern completion during spatial associative memory recall does not require the NMDA receptor in the hippocampus or forebrain.

  7. European utility requirements (EUR) volume 3 assessment for AP1000

    International Nuclear Information System (INIS)

    Saiu, G.; Demetri, K.J.

    2005-01-01

    The EUR (European Utility Requirements) Volume 3 is intended to report the Plant Description, the Compliance Assessment to EUR Volumes 1 and 2, and finally, the Specific Requirements for each specific Nuclear Power Plant Design considered by the EUR. Five subsets of EUR Volume 3, based on EUR Revision B, are already published; all of which are next generation plant designs being developed for Europe beyond 2000. They include : 1) EP1000 - Passive Pressurized Light Water Reactor (3-Loop, 1000 MWe) 2) EPR - Evolutionary Pressurized Light Water Reactor (1500 MWe) 3) BWR90/90+ - Evolutionary Boiling Water Reactor (1400 MWe) 4) ABWR - Evolutionary Boiling Water Reactor (1400 MWe) 5) SWR 1000 - Boiling Water Reactor With Passive Features (1000 MWe) In addition, the following subsets are currently being developed: 1) AP1000 - Passive Pressurized Light Water Reactor (2-Loop, 1117 MWe) 2) VVER AES 92 - Pressurized Water Reactor With Passive Features (1000 MWe) The purpose of this paper is to provide an overview of the program, which started in January 2004 with the EUR group to prepare an EUR Volume 3 Subset for the AP1000 nuclear plant design. The AP1000 EUR compliance assessment, to be performed against EUR Revision C requirements, is an important step for the evaluation of the AP1000 design for application in Europe. The AP1000 compliance assessment is making full use of AP1000 licensing documentation, EPP Phase 2 design activities and EP1000 EUR detailed compliance assessment. As of today, nearly all of the EUR Chapters have been discussed within the EUR Coordination Group. Based on the results of the compliance assessment, it can be stated that the AP1000 design shows a good level of compliance with the EUR Revision C requirements. Nevertheless, the compliance assessment has highlighted areas for where the AP1000 plant deviates from the EUR. The EPP design group has selected the most significant ones for performing detailed studies to quantify the degree of compliance

  8. Functional Requirements for Onboard Management of Space Shuttle Consumables. Volume 2

    Science.gov (United States)

    Graf, P. J.; Herwig, H. A.; Neel, L. W.

    1973-01-01

    This report documents the results of the study "Functional Requirements for Onboard Management of Space Shuttle Consumables." The study was conducted for the Mission Planning and Analysis Division of the NASA Lyndon B. Johnson Space Center, Houston, Texas, between 3 July 1972 and 16 November 1973. The overall study program objective was two-fold. The first objective was to define a generalized consumable management concept which is applicable to advanced spacecraft. The second objective was to develop a specific consumables management concept for the Space Shuttle vehicle and to generate the functional requirements for the onboard portion of that concept. Consumables management is the process of controlling or influencing the usage of expendable materials involved in vehicle subsystem operation. The report consists of two volumes. Volume I presents a description of the study activities related to general approaches for developing consumable management, concepts for advanced spacecraft applications, and functional requirements for a Shuttle consumables management concept. Volume II presents a detailed description of the onboard consumables management concept proposed for use on the Space Shuttle.

  9. Planck/SDSS Cluster Mass and Gas Scaling Relations for a Volume-Complete redMaPPer Sample

    Science.gov (United States)

    Jimeno, Pablo; Diego, Jose M.; Broadhurst, Tom; De Martino, I.; Lazkoz, Ruth

    2018-04-01

    Using Planck satellite data, we construct Sunyaev-Zel'dovich (SZ) gas pressure profiles for a large, volume-complete sample of optically selected clusters. We have defined a sample of over 8,000 redMaPPer clusters from the Sloan Digital Sky Survey (SDSS), within the volume-complete redshift region 0.100 trend towards larger break radius with increasing cluster mass. Our SZ-based masses fall ˜16% below the mass-richness relations from weak lensing, in a similar fashion as the "hydrostatic bias" related with X-ray derived masses. Finally, we derive a tight Y500-M500 relation over a wide range of cluster mass, with a power law slope equal to 1.70 ± 0.07, that agrees well with the independent slope obtained by the Planck team with an SZ-selected cluster sample, but extends to lower masses with higher precision.

  10. Tumor Volume Changes Assessed by Three-Dimensional Magnetic Resonance Volumetry in Rectal Cancer Patients After Preoperative Chemoradiation: The Impact of the Volume Reduction Ratio on the Prediction of Pathologic Complete Response

    International Nuclear Information System (INIS)

    Kang, Jeong Hyun; Kim, Young Chul; Kim, Hyunki; Kim, Young Wan; Hur, Hyuk; Kim, Jin Soo; Min, Byung Soh; Kim, Hogeun; Lim, Joon Seok; Seong, Jinsil; Keum, Ki Chang; Kim, Nam Kyu

    2010-01-01

    Purpose: The aim of this study was to determine the correlation between tumor volume changes assessed by three-dimensional (3D) magnetic resonance (MR) volumetry and the histopathologic tumor response in rectal cancer patients undergoing preoperative chemoradiation therapy (CRT). Methods and Materials: A total of 84 patients who underwent preoperative CRT followed by radical surgery were prospectively enrolled in the study. The post-treatment tumor volume and tumor volume reduction ratio (% decrease ratio), as shown by 3D MR volumetry, were compared with the histopathologic response, as shown by T and N downstaging and the tumor regression grade (TRG). Results: There were no significant differences in the post-treatment tumor volume and the volume reduction ratio shown by 3D MR volumetry with respect to T and N downstaging and the tumor regression grade. In a multivariate analysis, the tumor volume reduction ratio was not significantly associated with T and N downstaging. The volume reduction ratio (>75%, p = 0.01) and the pretreatment carcinoembryonic antigen level (≤3 ng/ml, p = 0.01), but not the post-treatment volume shown by 3D MR (≤ 5ml), were, however, significantly associated with an increased pathologic complete response rate. Conclusion: More than 75% of the tumor volume reduction ratios were significantly associated with a high pathologic complete response rate. Therefore, limited treatment options such as local excision or simple observation might be considered after preoperative CRT in this patient population.

  11. Satellite Power Systems (SPS) concept definition study. Volume 6: SPS technology requirements and verification

    Science.gov (United States)

    Hanley, G.

    1978-01-01

    Volume 6 of the SPS Concept Definition Study is presented and also incorporates results of NASA/MSFC in-house effort. This volume includes a supporting research and technology summary. Other volumes of the final report that provide additional detail are as follows: (1) Executive Summary; (2) SPS System Requirements; (3) SPS Concept Evolution; (4) SPS Point Design Definition; (5) Transportation and Operations Analysis; and Volume 7, SPS Program Plan and Economic Analysis.

  12. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 4

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 4) presents the standards and requirements for the following sections: Radiation Protection and Operations.

  13. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 4

    International Nuclear Information System (INIS)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 4) presents the standards and requirements for the following sections: Radiation Protection and Operations

  14. Lung volumes: measurement, clinical use, and coding.

    Science.gov (United States)

    Flesch, Judd D; Dine, C Jessica

    2012-08-01

    Measurement of lung volumes is an integral part of complete pulmonary function testing. Some lung volumes can be measured during spirometry; however, measurement of the residual volume (RV), functional residual capacity (FRC), and total lung capacity (TLC) requires special techniques. FRC is typically measured by one of three methods. Body plethysmography uses Boyle's Law to determine lung volumes, whereas inert gas dilution and nitrogen washout use dilution properties of gases. After determination of FRC, expiratory reserve volume and inspiratory vital capacity are measured, which allows the calculation of the RV and TLC. Lung volumes are commonly used for the diagnosis of restriction. In obstructive lung disease, they are used to assess for hyperinflation. Changes in lung volumes can also be seen in a number of other clinical conditions. Reimbursement for measurement of lung volumes requires knowledge of current procedural terminology (CPT) codes, relevant indications, and an appropriate level of physician supervision. Because of recent efforts to eliminate payment inefficiencies, the 10 previous CPT codes for lung volumes, airway resistance, and diffusing capacity have been bundled into four new CPT codes.

  15. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 5

    International Nuclear Information System (INIS)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 5) outlines the standards and requirements for the Fire Protection and Packaging and Transportation sections

  16. Complete 360° circumferential SSOCT gonioscopy of the iridocorneal angle

    Science.gov (United States)

    McNabb, Ryan P.; Kuo, Anthony N.; Izatt, Joseph A.

    2014-02-01

    The ocular iridocorneal angle is generally an optically inaccessible area when viewed directly through the cornea due to the high angle of incidence required and the large index of refraction difference between air and cornea (nair = 1.000 and ncornea = 1.376) resulting in total internal reflection. Gonioscopy allows for viewing of the angle by removing the aircornea interface through the use of a special contact lens on the eye. Gonioscopy is used clinically to visualize the angle directly but only en face. Optical coherence tomography (OCT) has been used to image the angle and deeper structures via an external approach. Typically, this imaging technique is performed by utilizing a conventional anterior segment OCT scanning system. However, instead of imaging the apex of the cornea, either the scanner or the subject is tilted such that the corneoscleral limbus is orthogonal to the optical axis of the scanner requiring multiple volumes to obtain complete circumferential coverage of the ocular angle. We developed a novel gonioscopic OCT (GOCT) system that images the entire ocular angle within a single volume via an "internal" approach through the use of a custom radially symmetric gonioscopic contact lens. We present, to our knowledge, the first complete 360° circumferential volumes of the iridocorneal angle from a direct, internal approach.

  17. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 2

    International Nuclear Information System (INIS)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Document (S/RID) is contained in multiple volumes. This document (Volume 2) presents the standards and requirements for the following sections: Quality Assurance, Training and Qualification, Emergency Planning and Preparedness, and Construction

  18. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Document (S/RID) is contained in multiple volumes. This document (Volume 2) presents the standards and requirements for the following sections: Quality Assurance, Training and Qualification, Emergency Planning and Preparedness, and Construction.

  19. High level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 6

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 6) outlines the standards and requirements for the sections on: Environmental Restoration and Waste Management, Research and Development and Experimental Activities, and Nuclear Safety.

  20. High level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 6

    International Nuclear Information System (INIS)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 6) outlines the standards and requirements for the sections on: Environmental Restoration and Waste Management, Research and Development and Experimental Activities, and Nuclear Safety

  1. The Gift Code User Manual. Volume I. Introduction and Input Requirements

    Science.gov (United States)

    1975-07-01

    REPORT & PERIOD COVERED ‘TII~ GIFT CODE USER MANUAL; VOLUME 1. INTRODUCTION AND INPUT REQUIREMENTS FINAL 6. PERFORMING ORG. REPORT NUMBER ?. AuTHOR(#) 8...reverua side if neceaeary and identify by block number] (k St) The GIFT code is a FORTRANcomputerprogram. The basic input to the GIFT ode is data called

  2. Complete cumulative index (1963-1983)

    International Nuclear Information System (INIS)

    1983-01-01

    This complete cumulative index covers all regular and special issues and supplements published by Atomic Energy Review (AER) during its lifetime (1963-1983). The complete cumulative index consists of six Indexes: the Index of Abstracts, the Subject Index, the Title Index, the Author Index, the Country Index and the Table of Elements Index. The complete cumulative index supersedes the Cumulative Indexes for Volumes 1-7: 1963-1969 (1970), and for Volumes 1-10: 1963-1972 (1972); this Index also finalizes Atomic Energy Review, the publication of which has recently been terminated by the IAEA

  3. Detailed requirements document for the Interactive Financial Management System (IFMS), volume 1

    Science.gov (United States)

    Dodson, D. B.

    1975-01-01

    The detailed requirements for phase 1 (online fund control, subauthorization accounting, and accounts receivable functional capabilities) of the Interactive Financial Management System (IFMS) are described. This includes information on the following: systems requirements, performance requirements, test requirements, and production implementation. Most of the work is centered on systems requirements, and includes discussions on the following processes: resources authority, allotment, primary work authorization, reimbursable order acceptance, purchase request, obligation, cost accrual, cost distribution, disbursement, subauthorization performance, travel, accounts receivable, payroll, property, edit table maintenance, end-of-year, backup input. Other subjects covered include: external systems interfaces, general inquiries, general report requirements, communication requirements, and miscellaneous. Subjects covered under performance requirements include: response time, processing volumes, system reliability, and accuracy. Under test requirements come test data sources, general test approach, and acceptance criteria. Under production implementation come data base establishment, operational stages, and operational requirements.

  4. Verification and validation guidelines for high integrity systems. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D. [SoHaR, Inc., Beverly Hills, CA (United States)

    1995-03-01

    High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities.

  5. Verification and validation guidelines for high integrity systems. Volume 1

    International Nuclear Information System (INIS)

    Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D.

    1995-03-01

    High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities

  6. Weapon container catalog. Volumes 1 & 2

    Energy Technology Data Exchange (ETDEWEB)

    Brown, L.A.; Higuera, M.C.

    1998-02-01

    The Weapon Container Catalog describes H-gear (shipping and storage containers, bomb hand trucks and the ancillary equipment required for loading) used for weapon programs and for special use containers. When completed, the catalog will contain five volumes. Volume 1 for enduring stockpile programs (B53, B61, B83, W62, W76, W78, W80, W84, W87, and W88) and Volume 2, Special Use Containers, are being released. The catalog is intended as a source of information for weapon program engineers and also provides historical information. The catalog also will be published on the SNL Internal Web and will undergo periodic updates.

  7. 33 CFR 96.320 - What is involved to complete a safety management audit and when is it required to be completed?

    Science.gov (United States)

    2010-07-01

    ... Safety Management (ISM) Code by Administrations. (3) Make sure the audit is carried out by a team of... safety management audit and when is it required to be completed? 96.320 Section 96.320 Navigation and... SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS How Will Safety Management Systems Be...

  8. Mars power system concept definition study. Volume 1: Study results

    Science.gov (United States)

    Littman, Franklin D.

    1994-01-01

    A preliminary top level study was completed to define power system concepts applicable to Mars surface applications. This effort included definition of power system requirements and selection of power systems with the potential for high commonality. These power systems included dynamic isotope, Proton Exchange Membrane (PEM) regenerative fuel cell, sodium sulfur battery, photovoltaic, and reactor concepts. Design influencing factors were identified. Characterization studies were then done for each concept to determine system performance, size/volume, and mass. Operations studies were done to determine emplacement/deployment maintenance/servicing, and startup/shutdown requirements. Technology development roadmaps were written for each candidate power system (included in Volume 2). Example power system architectures were defined and compared on a mass basis. The dynamic isotope power system and nuclear reactor power system architectures had significantly lower total masses than the photovoltaic system architectures. Integrated development and deployment time phasing plans were completed for an example DIPS and reactor architecture option to determine the development strategies required to meet the mission scenario requirements.

  9. A NEARLY VOLUME-COMPLETE SPECTROSCOPIC SURVEY OF THE CLOSESTMID-TO-LATE M DWARFS

    Science.gov (United States)

    Winters, Jennifer; Irwin, Jonathan; Newton, Elisabeth; Charbonneau, David; Latham, David W.; Mink, Jessica; Esquerdo, Gil; Berlind, Perry; Calkins, Mike

    2018-01-01

    Recent results from Kepler estimate that M dwarfs harbor 2.5 planets per star. Yet, we will understand our exoplanet discoveries only as well as we understand their host stars, and much remains unknown about our low-mass stellar neighbors, such as their kinematics, ages, and multiplicity. A nearly volume-complete sample of M dwarfs lies within 15 pc of the Sun, and it is only for planets orbiting these nearest and smallest stars that thorough follow-up work for characterization will be possible. Unfortunately, more than half of this sample have only low-resolution (R SMARTS) 1.5m. We present here results from year one of our TRES survey. We have measured radial velocities, rotational broadening, and H-alpha equivalent widths for 305 mid-to-late M dwarfs. We have discovered five new spectroscopic binaries, one of which is a rare M dwarf - (likely) brown dwarf binary within 10 pc, for which we have determined the orbit.Our survey more than doubles the number of mid-M dwarfs within 15 pc with complete high-resolution spectroscopic and trigonometric characterization. We hope to provide a legacy dataset for the use of future generations of astronomers.This work is being supported by grants from the National Science Foundation and the John Templeton Foundation.

  10. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 7. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Burt, D.L.

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 7) presents the standards and requirements for the following sections: Occupational Safety and Health, and Environmental Protection.

  11. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 7. Revision 1

    International Nuclear Information System (INIS)

    Burt, D.L.

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 7) presents the standards and requirements for the following sections: Occupational Safety and Health, and Environmental Protection

  12. The adequate rocuronium dose required for complete block of the adductor muscles of the thigh.

    Science.gov (United States)

    Fujimoto, M; Kawano, K; Yamamoto, T

    2018-03-01

    Rocuronium can prevent the obturator jerk during transurethral resection of bladder tumors. We investigated the adequate rocuronium dose required for complete block of the thigh adductor muscles, and its correlation with individual responses of the adductor pollicis muscle to rocuronium. Eleven patients scheduled for transurethral resection of bladder tumors under general anesthesia were investigated. After general anesthesia induction, neuromuscular monitoring of the adductor pollicis muscle and ultrasonography-guided stimulation of the obturator nerve was commenced. Rocuronium, 0.15 mg/kg, was repeatedly administered intravenously. The adequate rocuronium dose required for complete block of the thigh muscles, defined as the cumulative dose of rocuronium administered until that time, and its correlation with the first twitch response of the adductor pollicis muscle on train-of-four stimulation after initial rocuronium administration was analyzed. The rocuronium dose found adequate for complete block of the thigh muscles was 0.30 mg/kg in seven patients and 0.45 mg/kg in the remaining four patients, which did not correlate with the first twitch response. At the time of complete block of the thigh muscles, the neuromuscular blockade level of the adductor pollicis muscle varied greatly, although the level was never more profound than a post-tetanic count of 1. Although the response of the adductor pollicis muscle to rocuronium cannot be used to determine the adequate rocuronium dose required for complete block of the thigh muscles, intense blockade, with maintenance of post-tetanic count at ≤ 1 in the adductor pollicis muscle is essential to prevent the obturator jerk. © 2017 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  13. Requirements for Certification of Teachers, Counselors, Librarians, Administrators for Elementary and Secondary Schools. Seventy-Seventh Edition, 2012-2013

    Science.gov (United States)

    Kaye, Elizabeth A., Ed.

    2012-01-01

    This annual volume offers the most complete and current listings of the requirements for certification of a wide range of educational professionals at the elementary and secondary levels. "Requirements for Certification" is a valuable resource, making much-needed knowledge available in one straightforward volume. [For "Requirements for…

  14. Space Assembly, Maintenance and Servicing Study. Volume 4: Concept Development Plan

    National Research Council Canada - National Science Library

    1986-01-01

    .... This concept development program (CDP), Volume IV of the SAMS final report, contains a summary of the selection of CDP candidates and a plan for completing the required analysis, tests and demonstrations...

  15. Atlas-Based Segmentation Improves Consistency and Decreases Time Required for Contouring Postoperative Endometrial Cancer Nodal Volumes

    International Nuclear Information System (INIS)

    Young, Amy V.; Wortham, Angela; Wernick, Iddo; Evans, Andrew; Ennis, Ronald D.

    2011-01-01

    Purpose: Accurate target delineation of the nodal volumes is essential for three-dimensional conformal and intensity-modulated radiotherapy planning for endometrial cancer adjuvant therapy. We hypothesized that atlas-based segmentation ('autocontouring') would lead to time savings and more consistent contours among physicians. Methods and Materials: A reference anatomy atlas was constructed using the data from 15 postoperative endometrial cancer patients by contouring the pelvic nodal clinical target volume on the simulation computed tomography scan according to the Radiation Therapy Oncology Group 0418 trial using commercially available software. On the simulation computed tomography scans from 10 additional endometrial cancer patients, the nodal clinical target volume autocontours were generated. Three radiation oncologists corrected the autocontours and delineated the manual nodal contours under timed conditions while unaware of the other contours. The time difference was determined, and the overlap of the contours was calculated using Dice's coefficient. Results: For all physicians, manual contouring of the pelvic nodal target volumes and editing the autocontours required a mean ± standard deviation of 32 ± 9 vs. 23 ± 7 minutes, respectively (p = .000001), a 26% time savings. For each physician, the time required to delineate the manual contours vs. correcting the autocontours was 30 ± 3 vs. 21 ± 5 min (p = .003), 39 ± 12 vs. 30 ± 5 min (p = .055), and 29 ± 5 vs. 20 ± 5 min (p = .0002). The mean overlap increased from manual contouring (0.77) to correcting the autocontours (0.79; p = .038). Conclusion: The results of our study have shown that autocontouring leads to increased consistency and time savings when contouring the nodal target volumes for adjuvant treatment of endometrial cancer, although the autocontours still required careful editing to ensure that the lymph nodes at risk of recurrence are properly included in the target volume.

  16. Requirements for Certification of Teachers, Counselors, Librarians, Administrators for Elementary and Secondary Schools. Seventy-Sixth Edition, 2011-2012

    Science.gov (United States)

    Kaye, Elizabeth A., Ed.

    2011-01-01

    This annual volume offers the most complete and current listings of the requirements for certification of a wide range of educational professionals at the elementary and secondary levels. "Requirements for Certification" is a valuable resource, making much-needed knowledge available in one straightforward volume. [For "Requirements…

  17. Requirements for Certification of Teachers, Counselors, Librarians, Administrators for Elementary and Secondary Schools. Seventy-Fifth Edition, 2010-2011

    Science.gov (United States)

    Kaye, Elizabeth A., Ed.; Makos, Jeffrey J., Ed.

    2010-01-01

    This annual volume offers the most complete and current listings of the requirements for certification of a wide range of educational professionals at the elementary and secondary levels. "Requirements for Certification" is a valuable resource, making much-needed knowledge available in one straightforward volume. Appended are: (1) How to…

  18. The complete cosmicomics

    CERN Document Server

    Calvino, Italo

    2014-01-01

    The definitive edition of Calvino’s cosmicomics, bringing together all of these enchanting stories—including some never before translated—in one volume for the first time. In Italo Calvino’s cosmicomics, primordial beings cavort on the nearby surface of the moon, play marbles with atoms, and bear ecstatic witness to Earth’s first dawn. Exploring natural phenomena and the origins of the universe, these beloved tales relate complex scientific concepts to our common sensory, emotional, human world. Now, The Complete Cosmicomics brings together all of the cosmicomic stories for the first time. Containing works previously published in Cosmicomics, t zero, and Numbers in the Dark, this single volume also includes seven previously uncollected stories, four of which have never been published in translation in the United States. This “complete and definitive collection” (Evening Standard) reconfirms the cosmicomics as a crowning literary achievement and makes them available to new generations of reader...

  19. Automata learning algorithms and processes for providing more complete systems requirements specification by scenario generation, CSP-based syntax-oriented model construction, and R2D2C system requirements transformation

    Science.gov (United States)

    Hinchey, Michael G. (Inventor); Margaria, Tiziana (Inventor); Rash, James L. (Inventor); Rouff, Christopher A. (Inventor); Steffen, Bernard (Inventor)

    2010-01-01

    Systems, methods and apparatus are provided through which in some embodiments, automata learning algorithms and techniques are implemented to generate a more complete set of scenarios for requirements based programming. More specifically, a CSP-based, syntax-oriented model construction, which requires the support of a theorem prover, is complemented by model extrapolation, via automata learning. This may support the systematic completion of the requirements, the nature of the requirement being partial, which provides focus on the most prominent scenarios. This may generalize requirement skeletons by extrapolation and may indicate by way of automatically generated traces where the requirement specification is too loose and additional information is required.

  20. 77 FR 28281 - Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume...

    Science.gov (United States)

    2012-05-14

    ... Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical...]amino]- (CAS No. 1324-76-1), also known as C.I. Pigment Blue 61. EPA received an adverse comment regarding C.I. Pigment Blue 61. This document withdraws the revocation of testing requirements for C.I...

  1. NRC review of Electric Power Research Institute's advanced light water reactor utility requirements document. Passive plant designs, chapter 1, project number 669

    International Nuclear Information System (INIS)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the open-quotes Advanced Light Water Reactor [ALWR] Utility Requirements Documentclose quotes, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume 1, open-quotes ALWR Policy and Summary of Top-Tier Requirementsclose quotes, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, open-quotes NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Program Summaryclose quotes, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  2. Significance and clinical value of the transitional zone volume (TZV ...

    African Journals Online (AJOL)

    M. El Ghoneimy

    2017-01-12

    Jan 12, 2017 ... Objective: The aim of this work was to evaluate the significance and clinical value of the TZI, which has been a point of ... Conclusion: Estimating the transition zone volume during TRUS is a reasonable way to obtain the required ... Besides the IPSS score, a complete medical and surgical history was also.

  3. NRC review of Electric Power Research Institute's advanced light water reactor utility requirements document. Passive plant designs, chapters 2-13, project number 669

    International Nuclear Information System (INIS)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the open-quotes Advanced Light Water Reactor [ALWR] Utility Requirements Documentclose quotes, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume I, open-quotes ALWR Policy and Summary of Top-Tier Requirementsclose quotes, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, open-quotes NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Program Summaryclose quotes, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  4. Quantifying Uncertainty in Soil Volume Estimates

    International Nuclear Information System (INIS)

    Roos, A.D.; Hays, D.C.; Johnson, R.L.; Durham, L.A.; Winters, M.

    2009-01-01

    Proper planning and design for remediating contaminated environmental media require an adequate understanding of the types of contaminants and the lateral and vertical extent of contamination. In the case of contaminated soils, this generally takes the form of volume estimates that are prepared as part of a Feasibility Study for Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites and/or as part of the remedial design. These estimates are typically single values representing what is believed to be the most likely volume of contaminated soil present at the site. These single-value estimates, however, do not convey the level of confidence associated with the estimates. Unfortunately, the experience has been that pre-remediation soil volume estimates often significantly underestimate the actual volume of contaminated soils that are encountered during the course of remediation. This underestimation has significant implications, both technically (e.g., inappropriate remedial designs) and programmatically (e.g., establishing technically defensible budget and schedule baselines). Argonne National Laboratory (Argonne) has developed a joint Bayesian/geostatistical methodology for estimating contaminated soil volumes based on sampling results, that also provides upper and lower probabilistic bounds on those volumes. This paper evaluates the performance of this method in a retrospective study that compares volume estimates derived using this technique with actual excavated soil volumes for select Formerly Utilized Sites Remedial Action Program (FUSRAP) Maywood properties that have completed remedial action by the U.S. Army Corps of Engineers (USACE) New York District. (authors)

  5. Journal of Special Operations Medicine, Volume 2, Edition 3

    Science.gov (United States)

    2002-01-01

    muscle necrosis is extensive it produces a tissue lysis syndrome with lactic acidosis, hyperkalemia, hyperuricemia, hyperphosphatemia, hypocalcemia ... adults , and may require adjust- ment for elderly or very young patients. Volume 2, Edition 3 / Summer 02 27 6. Costrini A: Emergency treatment of...completed annual refresher training in direct laryngoscopy three days prior to this study. A LaedralTM adult intubating manikin was used as the patient in

  6. Geostatistical approach for assessing soil volumes requiring remediation: validation using lead-polluted soils underlying a former smelting works.

    Science.gov (United States)

    Demougeot-Renard, Helene; De Fouquet, Chantal

    2004-10-01

    Assessing the volume of soil requiring remediation and the accuracy of this assessment constitutes an essential step in polluted site management. If this remediation volume is not properly assessed, misclassification may lead both to environmental risks (polluted soils may not be remediated) and financial risks (unexpected discovery of polluted soils may generate additional remediation costs). To minimize such risks, this paper proposes a geostatistical methodology based on stochastic simulations that allows the remediation volume and the uncertainty to be assessed using investigation data. The methodology thoroughly reproduces the conditions in which the soils are classified and extracted at the remediation stage. The validity of the approach is tested by applying it on the data collected during the investigation phase of a former lead smelting works and by comparing the results with the volume that has actually been remediated. This real remediated volume was composed of all the remediation units that were classified as polluted after systematic sampling and analysis during clean-up stage. The volume estimated from the 75 samples collected during site investigation slightly overestimates (5.3% relative error) the remediated volume deduced from 212 remediation units. Furthermore, the real volume falls within the range of uncertainty predicted using the proposed methodology.

  7. Petroleum industry in Latin America: volume III Argentina, Bolivia, Mexico, Peru

    International Nuclear Information System (INIS)

    Reinsch, A.E.; Tissot, R.R.

    1995-01-01

    As the previous volume in this series, this concluding volume was divided into separately paged sections, one for each of Argentina, Bolivia, Mexico and Peru, each section being complete in itself. For each of the countries dealt with, there was a brief historical introduction, followed by a detailed analysis of its energy sector, a description of the physical and market characteristics, the transportation and infrastructure systems, the legal and regulatory issues pertaining to the petroleum industry, especially as regards investment and environmental requirements, and an analysis of the prevailing political climate. figs., tabs., refs

  8. Development of an Inline Dry Power Inhaler That Requires Low Air Volume.

    Science.gov (United States)

    Farkas, Dale; Hindle, Michael; Longest, P Worth

    2017-12-20

    Inline dry powder inhalers (DPIs) are actuated by an external air source and have distinct advantages for delivering aerosols to infants and children, and to individuals with compromised lung function or who require ventilator support. However, current inline DPIs either perform poorly, are difficult to operate, and/or require large volumes (∼1 L) of air. The objective of this study was to develop and characterize a new inline DPI for aerosolizing spray-dried formulations with powder masses of 10 mg and higher using a dispersion air volume of 10 mL per actuation that is easy to load (capsule-based) and operate. Primary features of the new low air volume (LV) DPIs are fixed hollow capillaries that both pierce the capsule and provide a continuous flow path for air and aerosol passing through the device. Two different configurations were evaluated, which were a straight-through (ST) device, with the inlet and outlet capillaries on opposite ends of the capsule, and a single-sided (SS) device, with both the inlet and outlet capillaries on the same side of the capsule. The devices were operated with five actuations of a 10 mL air syringe using an albuterol sulfate (AS) excipient-enhanced growth (EEG) formulation. Device emptying and aerosol characteristics were evaluated for multiple device outlet configurations. Each device had specific advantages. The best case ST device produced the smallest aerosol [mean mass median aerodynamic diameter (MMAD) = 1.57 μm; fine particle fraction <5 μm (FPF <5μm ) = 95.2%)] but the mean emitted dose (ED) was 61.9%. The best case SS device improved ED (84.8%), but produced a larger aerosol (MMAD = 2.13 μm; FPF <5μm  = 89.3%) that was marginally higher than the initial deaggregation target. The new LV-DPIs produced an acceptable high-quality aerosol with only 10 mL of dispersion air per actuation and were easy to load and operate. This performance should enable application in high and low flow

  9. Volume reduction of contaminated filter wastes

    International Nuclear Information System (INIS)

    Buttedahl, O.I.; Terada, K.

    1976-01-01

    Reported are details of a pilot project to design and construct a compactor to reduce the handling of high efficiency particulate air (HEPA) filters used in air filtration systems at facilities where radioactive materials are processed. In such systems at Rocky Flats Plant, filters require frequent change and removal. Large quantities are used and will be increased for future operations. With the completion of the pilot model, it has been demonstrated that volume reductions of more than 80% can be achieved and cost savings will be realized also

  10. New simple method for fast and accurate measurement of volumes

    International Nuclear Information System (INIS)

    Frattolillo, Antonio

    2006-01-01

    A new simple method is presented, which allows us to measure in just a few minutes but with reasonable accuracy (less than 1%) the volume confined inside a generic enclosure, regardless of the complexity of its shape. The technique proposed also allows us to measure the volume of any portion of a complex manifold, including, for instance, pipes and pipe fittings, valves, gauge heads, and so on, without disassembling the manifold at all. To this purpose an airtight variable volume is used, whose volume adjustment can be precisely measured; it has an overall capacity larger than that of the unknown volume. Such a variable volume is initially filled with a suitable test gas (for instance, air) at a known pressure, as carefully measured by means of a high precision capacitive gauge. By opening a valve, the test gas is allowed to expand into the previously evacuated unknown volume. A feedback control loop reacts to the resulting finite pressure drop, thus contracting the variable volume until the pressure exactly retrieves its initial value. The overall reduction of the variable volume achieved at the end of this process gives a direct measurement of the unknown volume, and definitively gets rid of the problem of dead spaces. The method proposed actually does not require the test gas to be rigorously held at a constant temperature, thus resulting in a huge simplification as compared to complex arrangements commonly used in metrology (gas expansion method), which can grant extremely accurate measurement but requires rather expensive equipments and results in time consuming methods, being therefore impractical in most applications. A simple theoretical analysis of the thermodynamic cycle and the results of experimental tests are described, which demonstrate that, in spite of its simplicity, the method provides a measurement accuracy within 0.5%. The system requires just a few minutes to complete a single measurement, and is ready immediately at the end of the process. The

  11. The Completeness Theorem of Gödel - An Introduction to ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 7. The Completeness Theorem of Gödel - An Introduction to Mathematical Logic. S M Srivastava. General Article Volume 6 Issue 7 July 2001 pp 29-41. Fulltext. Click here to view fulltext PDF. Permanent link:

  12. Dose and volume specification for reporting NCT. An ICRU-IAEA initiative

    International Nuclear Information System (INIS)

    Wambersie, A.; Gahbauer, R.A.; Whitmore, G.; Levin, C.V.

    2000-01-01

    The present recommendations result from of an ICRU-IAEA initiative for harmonization of reporting NCT (Neutron Capture Therapy). As stated by the ISNCT, harmonization of reporting is required to understand what has actually been done and interpret the clinical results on the basis of reliable information. Prescription of a treatment remains the responsibility of the radiation oncologist in charge of the patient. Complete oncological data should be reported, including Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) as well as Planning Target Volume (PTV), Treated Volume and Organs/Structures at Risk. A reference point for reporting dose should be selected in the central part of the PTV/CTV. At each point of interest, the four components contributing to the absorbed dose and the weighting factors applied to take account of the RBE (Relative Biological Effectiveness) differences should be specified. (author)

  13. Waste Management System Requirement document

    International Nuclear Information System (INIS)

    1990-04-01

    This volume defines the top level technical requirements for the Monitored Retrievable Storage (MRS) facility. It is designed to be used in conjunction with Volume 1, General System Requirements. Volume 3 provides a functional description expanding the requirements allocated to the MRS facility in Volume 1 and, when appropriate, elaborates on requirements by providing associated performance criteria. Volumes 1 and 3 together convey a minimum set of requirements that must be satisfied by the final MRS facility design without unduly constraining individual design efforts. The requirements are derived from the Nuclear Waste Policy Act of 1982 (NWPA), the Nuclear Waste Policy Amendments Act of 1987 (NWPAA), the Environmental Protection Agency's (EPA) Environmental Standards for the Management and Disposal of Spent Nuclear Fuel (40 CFR 191), NRC Licensing Requirements for the Independent Storage of Spent Nuclear and High-Level Radioactive Waste (10 CFR 72), and other federal statutory and regulatory requirements, and major program policy decisions. This document sets forth specific requirements that will be fulfilled. Each subsequent level of the technical document hierarchy will be significantly more detailed and provide further guidance and definition as to how each of these requirements will be implemented in the design. Requirements appearing in Volume 3 are traceable into the MRS Design Requirements Document. Section 2 of this volume provides a functional breakdown for the MRS facility. 1 tab

  14. Space transfer vehicle concepts and requirements, volume 2, book 1

    Science.gov (United States)

    1991-01-01

    The objective of the systems engineering task was to develop and implement an approach that would generate the required study products as defined by program directives. This product list included a set of system and subsystem requirements, a complete set of optimized trade studies and analyses resulting in a recommended system configuration, and the definition of an integrated system/technology and advanced development growth path. A primary ingredient in the approach was the TQM philosophy stressing job quality from the inception. Included throughout the Systems Engineering, Programmatics, Concepts, Flight Design, and Technology sections are data supporting the original objectives as well as supplemental information resulting from program activities. The primary result of the analyses and studies was the recommendation of a single propulsion stage Lunar Transportation System (LTS) configuration that supports several different operations scenarios with minor element changes. This concept has the potential to support two additional scenarios with complex element changes. The space based LTS concept consists of three primary configurations--Piloted, Reusable Cargo, and Expendable Cargo.

  15. How Reading Volume Affects both Reading Fluency and Reading Achievement

    Directory of Open Access Journals (Sweden)

    Richard L. ALLINGTON

    2014-10-01

    Full Text Available Long overlooked, reading volume is actually central to the development of reading proficiencies, especially in the development of fluent reading proficiency. Generally no one in schools monitors the actual volume of reading that children engage in. We know that the commonly used commercial core reading programs provide only material that requires about 15 minutes of reading activity daily. The remaining 75 minute of reading lessons is filled with many other activities such as completing workbook pages or responding to low-level literal questions about what has been read. Studies designed to enhance the volume of reading that children do during their reading lessons demonstrate one way to enhance reading development. Repeated readings have been widely used in fostering reading fluency but wide reading options seem to work faster and more broadly in developing reading proficiencies, including oral reading fluency.

  16. Failure of college students to complete an online alcohol education course as a predictor of high-risk drinking that requires medical attention.

    Science.gov (United States)

    Abrams, Gina Baral; Kolligian, John; Mills, Douglas Lane; DeJong, William

    2011-11-01

    AlcoholEdu® for College and other computer-based education programs have been developed to reduce alcohol use and related problems among students. This study investigated whether the failure of incoming first-year students to complete AlcoholEdu predicts future high-risk drinking that requires medical attention. A review of clinical records kept by a single university's health service identified 684 undergraduates (classes of 2007-2011) who had presented for an alcohol event (September 2003 through June 2008). We used survival analysis to determine whether students who partially completed the course or failed to take it were disproportionately represented among student patients who presented with elevated blood alcohol concentration (BAC). Students who failed to take the online course were 4.64 times more likely than those who completed it to experience an alcohol event (p students who had partially completed the course were 1.52 times more likely (p alcohol education and gender were not significantly related to students' measured BAC level. Students who had completed AlcoholEdu were less likely to present for an alcohol event than were students who partially completed or failed to take the course. Campus administrators should consider whether students who fail to complete an online alcohol course should be flagged for more focused interventions (e.g., brief motivational interview, mandatory education classes). This is the first study to show a relationship between first-year college students' non-completion of an online alcohol course and subsequent high-risk drinking that requires medical attention.

  17. Management and technical requirements for laboratories in charge of water monitoring

    International Nuclear Information System (INIS)

    Ottaviani, M.; Bonadonna, L.; Lucentini, L.; Pettine, P.

    2008-01-01

    This report completes the series of volumes focused on microbiological (Rapporti ISTISAN 07/5) and chemical methods (Rapporti ISTISAN 07/31) for the monitoring of water intended for human consumption according to the Italian Legislative Decree 31/2001 (transposition of European Directive 98/83/EC) and its integrations. The guidelines here presented concern management and technical requirements for laboratories in charge of testing parameters required by the Decree also taking into account the criteria stated by the standard UNI CEI EN ISO/IEC 17025 [it

  18. Solid waste 30-year volume summary

    International Nuclear Information System (INIS)

    Valero, O.J.; Armacost, L.L.; DeForest, T.J.; Templeton, K.J.; Williams, N.C.

    1994-06-01

    A 30-year forecast of the solid waste volumes to be generated or received at the US Department of Energy Hanford Site is described in this report. The volumes described are low-level mixed waste (LLMW) and transuranic/transuranic mixed (TRU/TRUM) waste that will require treatment, storage, and disposal at Hanford's Solid Waste Operations Complex (SWOC) during the 30-year period from FY 1994 through FY 2023. The data used to complete this document were collected from onsite and offsite waste generators who currently, or are planning to, ship solid wastes to the Hanford Site. An analysis of the data suggests that over 300,000 m 3 of LLMW and TRU/TRUM waste will be managed at Hanford's SWOC over the next 30 years. An extensive effort was made this year to collect this information. The 1993 solid waste forecast was used as a starting point, which identified approximately 100,000 m 3 of LLMW and TRU/TRUM waste to be sent to the SWOC. After analyzing the forecast waste volume, it was determined that additional waste was expected from the tank waste remediation system (TWRS), onsite decontamination and decommissioning (D ampersand D) activities, and onsite remedial action (RA) activities. Data presented in this report establish a starting point for solid waste management planning. It is recognized that forecast estimates will vary (typically increasing) as facility planning and missions continue to change and become better defined, but the information presented still provides useful insight into Hanford's future solid waste management requirements

  19. Viability Assessment of a Repository at Yucca Mountain. Volume 4: License Application Plan and Costs

    Energy Technology Data Exchange (ETDEWEB)

    None

    1998-12-01

    Volume 4 provides the DOE plan and cost estimate for the remaining work necessary to proceed from completing this VA to submitting an LA to NRC. This work includes preparing an EIS and evaluating the suitability of the site. Both items are necessary components of the documentation required to support a decision in 2001 by the Secretary of Energy on whether or not to recommend that the President approve the site for development as a repository. If the President recommends the site to Congress and the site designation becomes effective, then DOE will submit the LA to NRC in 2002 for authorization to construct the repository. The work described in Volume 4 constitutes the last step in the characterization of the Yucca Mountain site and the design and evaluation of the performance of a repository system in the geologic setting of this site. The plans in this volume for the next 4 years' work are based on the results of the previous 15 years' work, as reported in Volumes 1, 2, and 3 of this VA. Volume 1 summarizes what DOE has learned to date about the Yucca Mountain site. Volume 2 describes the current, reference repository design, several design options that might enhance the performance of the reference design, and several alternative designs that represent substantial departures from the reference design. Volume 2 also summarizes the results of tests of candidate materials for waste packages and for support of the tunnels into which waste would be emplaced. Volume 3 provides the results of the latest performance assessments undertaken to evaluate the performance of the design in the geologic setting of Yucca Mountain. The results described in Volumes 1, 2, and 3 provide the basis for identifying and prioritizing the work described in this volume. DOE believes that the planned work, together with the results of previous work, will be sufficient to support a site suitability evaluation for site recommendation and, if the site is recommended and designated, a

  20. Subsurface Contamination Focus Area technical requirements. Volume 1: Requirements summary

    International Nuclear Information System (INIS)

    Nickelson, D.; Nonte, J.; Richardson, J.

    1996-10-01

    This document summarizes functions and requirements for remediation of source term and plume sites identified by the Subsurface Contamination Focus Area. Included are detailed requirements and supporting information for source term and plume containment, stabilization, retrieval, and selective retrieval remedial activities. This information will be useful both to the decision-makers within the Subsurface Contamination Focus Area (SCFA) and to the technology providers who are developing and demonstrating technologies and systems. Requirements are often expressed as graphs or charts, which reflect the site-specific nature of the functions that must be performed. Many of the tradeoff studies associated with cost savings are identified in the text

  1. MARS code manual volume II: input requirements

    International Nuclear Information System (INIS)

    Chung, Bub Dong; Kim, Kyung Doo; Bae, Sung Won; Jeong, Jae Jun; Lee, Seung Wook; Hwang, Moon Kyu

    2010-02-01

    Korea Advanced Energy Research Institute (KAERI) conceived and started the development of MARS code with the main objective of producing a state-of-the-art realistic thermal hydraulic systems analysis code with multi-dimensional analysis capability. MARS achieves this objective by very tightly integrating the one dimensional RELAP5/MOD3 with the multi-dimensional COBRA-TF codes. The method of integration of the two codes is based on the dynamic link library techniques, and the system pressure equation matrices of both codes are implicitly integrated and solved simultaneously. In addition, the Equation-Of-State (EOS) for the light water was unified by replacing the EOS of COBRA-TF by that of the RELAP5. This input manual provides a complete list of input required to run MARS. The manual is divided largely into two parts, namely, the one-dimensional part and the multi-dimensional part. The inputs for auxiliary parts such as minor edit requests and graph formatting inputs are shared by the two parts and as such mixed input is possible. The overall structure of the input is modeled on the structure of the RELAP5 and as such the layout of the manual is very similar to that of the RELAP. This similitude to RELAP5 input is intentional as this input scheme will allow minimum modification between the inputs of RELAP5 and MARS3.1. MARS3.1 development team would like to express its appreciation to the RELAP5 Development Team and the USNRC for making this manual possible

  2. Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

    KAUST Repository

    Sicat, Ronell Barrera

    2014-12-31

    This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined in the 4D domain jointly comprising the 3D volume and its 1D intensity range. Crucially, the computation of sparse pdf volumes exploits data coherence in 4D, resulting in a sparse representation with surprisingly low storage requirements. At run time, we dynamically apply transfer functions to the pdfs using simple and fast convolutions. Whereas standard low-pass filtering and down-sampling incur visible differences between resolution levels, the use of pdfs facilitates consistent results independent of the resolution level used. We describe the efficient out-of-core computation of large-scale sparse pdf volumes, using a novel iterative simplification procedure of a mixture of 4D Gaussians. Finally, our data structure is optimized to facilitate interactive multi-resolution volume rendering on GPUs.

  3. Interpolation for completely positive maps: Numerical solutions

    Czech Academy of Sciences Publication Activity Database

    Ambrozie, Calin-Grigore; Gheondea, A.

    2018-01-01

    Roč. 61, č. 1 (2018), s. 13-22 ISSN 1220-3874 Institutional support: RVO:67985840 Keywords : Choi matrix * completely positive * convex minimization Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.362, year: 2016 http://ssmr.ro/bulletin/volumes/61-1/node3.html

  4. The Necessary and Sufficient Closure Process Completion Report for Purex FacilitySurveillance and Maintenance

    International Nuclear Information System (INIS)

    Gerald, J.W.

    1997-10-01

    This document completes the U.S. Department of Energy Closure Process for Necessary and Sufficient Sets of Standards process for the Plutonium Uranium Extraction facility located at the Hanford Site in Washington State. This documentation is provided to support the Work Smart Standards set identified for the long-term surveillance and maintenance of PUREX. This report is organized into two volumes. Volume 1 contains the following sections: Section 1: Provides an introduction for the document Section 2: Provides a basis for initiating the N ampersand S process Section 3: Defines the work and hazards to be addressed Section 4: Identifies the N ampersand S set of standards and requirements Section 5: Provides the justification for adequacy of the work smart standards Section 6: Shows the criteria and qualifications of the teams Section 7: Describes the stakeholder participation and concerns Section 8: Provides a list of references used within the document

  5. Waste management system requirements document

    International Nuclear Information System (INIS)

    1991-02-01

    This volume defines the top level requirements for the Mined Geologic Disposal System (MGDS). It is designed to be used in conjunction with Volume 1 of the WMSR, General System Requirements. It provides a functional description expanding the requirements allocated to the MGDS in Volume 1 and elaborates on each requirement by providing associated performance criteria as appropriate. Volumes 1 and 4 of the WMSR provide a minimum set of requirements that must be satisfied by the final MGDS design. This document sets forth specific requirements that must be fulfilled. It is not the intent or purpose of this top level document to describe how each requirement is to be satisfied in the final MGDS design. Each subsequent level of the technical document hierarchy must provide further guidance and definition as to how each of these requirements is to be implemented in the design. It is expected that each subsequent level of requirements will be significantly more detailed. Section 2 of this volume provides a functional description of the MGDS. Each function is addressed in terms of requirements, and performance criteria. Section 3 provides a list of controlling documents. Each document cited in a requirement of Chapter 2 is included in this list and is incorporated into this document as a requirement on the final system. The WMSR addresses only federal requirements (i.e., laws, regulations and DOE orders). State and local requirements are not addressed. However, it will be specifically noted at the potentially affected WMSR requirements that there could be additional or more stringent regulations imposed by a state or local requirements or administering agency over the cited federal requirements

  6. Leak testing plan for the Oak Ridge National Laboratory liquid low-level waste systems (active tanks): Revision 2. Volume 1: Regulatory background and plan approach; Volume 2: Methods, protocols, and schedules; Volume 3: Evaluation of the ORNL/LT-823DP differential pressure leak detection method; Appendix to Revision 2: DOE/EPA/TDEC correspondence

    Energy Technology Data Exchange (ETDEWEB)

    Douglas, D.G.; Wise, R.F.; Starr, J.W.; Maresca, J.W. Jr. [Vista Research, Inc., Mountain View, CA (United States)

    1994-11-01

    This document, the Leak Testing Plan for the Oak Ridge National Laboratory Liquid Low-Level Waste System (Active Tanks), comprises three volumes. The first two volumes address the component-based leak testing plan for the liquid low-level waste system at Oak Ridge, while the third volume describes the performance evaluation of the leak detection method that will be used to test this system. Volume 1, describes that portion of the liquid low-level waste system at that will be tested; it provides the regulatory background, especially in terms of the requirements stipulated in the Federal Facilities Agreement, upon which the leak testing plan is based. Volume 1 also describes the foundation of the plan, portions of which were abstracted from existing federal documents that regulate the petroleum and hazardous chemicals industries. Finally, Volume 1 gives an overview the plan, describing the methods that will be used to test the four classes of components in the liquid low-level waste system. Volume 2 takes the general information on component classes and leak detection methods presented in Volume 1 and shows how it applies particularly to each of the individual components. A complete test plan for each of the components is presented, with emphasis placed on the methods designated for testing tanks. The protocol for testing tank systems is described, and general leak testing schedules are presented. Volume 3 describes the results of a performance evaluation completed for the leak testing method that will be used to test the small tanks at the facility (those less than 3,000 gal in capacity). Some of the details described in Volumes 1 and 2 are expected to change as additional information is obtained, as the viability of candidate release detection methods is proven in the Oak Ridge environment, and as the testing program evolves.

  7. Leak testing plan for the Oak Ridge National Laboratory liquid low-level waste systems (active tanks): Revision 2. Volume 1: Regulatory background and plan approach; Volume 2: Methods, protocols, and schedules; Volume 3: Evaluation of the ORNL/LT-823DP differential pressure leak detection method; Appendix to Revision 2: DOE/EPA/TDEC correspondence

    International Nuclear Information System (INIS)

    Douglas, D.G.; Wise, R.F.; Starr, J.W.; Maresca, J.W. Jr.

    1994-11-01

    This document, the Leak Testing Plan for the Oak Ridge National Laboratory Liquid Low-Level Waste System (Active Tanks), comprises three volumes. The first two volumes address the component-based leak testing plan for the liquid low-level waste system at Oak Ridge, while the third volume describes the performance evaluation of the leak detection method that will be used to test this system. Volume 1, describes that portion of the liquid low-level waste system at that will be tested; it provides the regulatory background, especially in terms of the requirements stipulated in the Federal Facilities Agreement, upon which the leak testing plan is based. Volume 1 also describes the foundation of the plan, portions of which were abstracted from existing federal documents that regulate the petroleum and hazardous chemicals industries. Finally, Volume 1 gives an overview the plan, describing the methods that will be used to test the four classes of components in the liquid low-level waste system. Volume 2 takes the general information on component classes and leak detection methods presented in Volume 1 and shows how it applies particularly to each of the individual components. A complete test plan for each of the components is presented, with emphasis placed on the methods designated for testing tanks. The protocol for testing tank systems is described, and general leak testing schedules are presented. Volume 3 describes the results of a performance evaluation completed for the leak testing method that will be used to test the small tanks at the facility (those less than 3,000 gal in capacity). Some of the details described in Volumes 1 and 2 are expected to change as additional information is obtained, as the viability of candidate release detection methods is proven in the Oak Ridge environment, and as the testing program evolves

  8. Completeness and Consistency in Hierarchical State-Based Requirements

    National Research Council Canada - National Science Library

    Heimdahl, Mats P. E

    1995-01-01

    .... The analysis algorithms and tools have been validated on TCAS II, a complex, airborne, collision-avoidance system required on all commercial aircraft with more than 30 passengers that fly in U.S. airspace.

  9. Users' requirements for IFMIF

    International Nuclear Information System (INIS)

    Noda, K.; Jitsukawa, S.; Ehrlich, K.; Moeslang, A.

    1998-01-01

    The International Fusion Materials Irradiation Facility (IFMIF) is a high energy neutron irradiation facility which generates an intense neutron flux with D-Li stripping reactions for fusion materials testing. The role of IFMIF is (1) development of various fusion reactor materials, (2) determination of design-relevant engineering databases for the DEMO fusion reactor, (3) calibration and validation of data generated from fission reactor irradiations and the other simulation experiments, etc. The conceptual design activity (CDA) of IFMIF was initiated in February 1995 as an IEA collaborative activity to complete a reference conceptual design of IFMIF in December 1996. Users' requirements for the conceptual design of IFMIF were developed for materials to be tested, types of experiments, small specimen test technology and irradiation conditions. Furthermore, the neutron irradiation field characteristics (spectrum, flux/volume, etc.) of IFMIF were evaluated for the conceptual design parameters and were shown to meet the essential requirements of the users. (orig.)

  10. Regulation, characterization and treatment of discharge waters from pipelines. Volume 1. Topical report, January 1989-April 1992. Executive summary

    International Nuclear Information System (INIS)

    Tallon, J.T.; Fillo, J.P.

    1992-04-01

    The report examines environmental issues related to hydrostatic testing of discharge waters generated from integrity testing of natural gas pipelines. Hydrostatic testing, and proper environmental management of the discharge waters, can be required by DOT regulations. However, disposal of water used to conduct a hydrostatic pipeline test is regulated on a state-by-state basis. State-specific requirements vary widely, ranging from an authorization letter to a complete NPDES permit. Monitoring may be required before and during discharge, include a variety of analyses, have varying protocols for obtaining samples, and may be required either to obtain data or to ascertain compliance with stipulated discharge limits. The composition of the discharge and state-specific discharge limitations dictate treatment needs on a case-by-case basis. The volume consists of the Executive Summary of a five-volume report series

  11. The complete flux scheme in cylindrical coordinates

    NARCIS (Netherlands)

    Anthonissen, M.J.H.; Thije Boonkkamp, ten J.H.M.

    2014-01-01

    We consider the complete ¿ux (CF) scheme, a ¿nite volume method (FVM) presented in [1]. CF is based on an integral representation for the ¿uxes, found by solving a local boundary value problem that includes the source term. It performs well (second order accuracy) for both diffusion and advection

  12. Complete Ureteral Avulsion

    Directory of Open Access Journals (Sweden)

    V. Gupta

    2005-01-01

    Full Text Available Complete avulsion of the ureter is one of the most serious complications of ureteroscopy. It requires open or laparoscopic intervention for repair. This case report emphasizes its management and presents recommendations for prevention in current urological practice.

  13. Non-completion and informed consent.

    Science.gov (United States)

    Wertheimer, Alan

    2014-02-01

    There is a good deal of biomedical research that does not produce scientifically useful data because it fails to recruit a sufficient number of subjects. This fact is typically not disclosed to prospective subjects. In general, the guidance about consent concerns the information required to make intelligent self-interested decisions and ignores some of the information required for intelligent altruistic decisions. Bioethics has worried about the 'therapeutic misconception', but has ignored the 'completion misconception'. This article argues that, other things being equal, prospective subjects should be informed about the possibility of non-completion as part of the standard consent process if (1) it is or should be anticipatable that there is a non-trivial possibility of non-completion and (2) that information is likely to be relevant to a prospective subject's decision to consent. The article then considers several objections to the argument, including the objection that disclosing non-completion information would make recruitment even more difficult.

  14. Preliminary evaluation of alternative waste form solidification processes. Volume II. Evaluation of the processes

    International Nuclear Information System (INIS)

    1980-08-01

    This Volume II presents engineering feasibility evaluations of the eleven processes for solidification of nuclear high-level liquid wastes (HHLW) described in Volume I of this report. Each evaluation was based in a systematic assessment of the process in respect to six principal evaluation criteria: complexity of process; state of development; safety; process requirements; development work required; and facility requirements. The principal criteria were further subdivided into a total of 22 subcriteria, each of which was assigned a weight. Each process was then assigned a figure of merit, on a scale of 1 to 10, for each of the subcriteria. A total rating was obtained for each process by summing the products of the subcriteria ratings and the subcriteria weights. The evaluations were based on the process descriptions presented in Volume I of this report, supplemented by information obtained from the literature, including publications by the originators of the various processes. Waste form properties were, in general, not evaluated. This document describes the approach which was taken, the developent and application of the rating criteria and subcriteria, and the evaluation results. A series of appendices set forth summary descriptions of the processes and the ratings, together with the complete numerical ratings assigned; two appendices present further technical details on the rating process

  15. VOLUME OF PHYSICAL ACTIVITY AND INJURY OCCURRENCE IN YOUNG BASKETBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Jenny Gianoudis

    2008-03-01

    Full Text Available Participation in organised, competitive physical activity by young athletes is increasing rapidly. This is concurrent with an increase in sporting injuries in the young population. This pilot study aimed to compare the weekly volume and types of physical activity in young basketball players injured and not injured during the season. Detailed physical activity and injury data were prospectively collected in 46 school-level basketball players aged 14 to 18 years. Participants completed physical activity logs which documented the type of physical activity undertaken, what the activity consisted of (i.e. training, competition and the level at which it was played on a daily basis. Allied health staff completed a weekly injury form. Results showed that injured and uninjured athletes participated in a similar volume of total weekly physical activity over the season. However, injured athletes (p = 0.04 and athletes who specifically sustained overuse injuries (p = 0.01 participated in a greater amount of basketball refereeing than uninjured athletes. Based on these findings it was concluded that greater participation in running-type physical activity such as refereeing, as an addition to training and competition, may predispose the young basketball player to increased injury risk. Future research using larger sample sizes are required to further investigate the role of participation volume and type on injury occurrence in adolescent athletes

  16. Developing and Evaluating Prototype of Waste Volume Monitoring Using Internet of Things

    Science.gov (United States)

    Fathhan Arief, Mohamad; Lumban Gaol, Ford

    2017-06-01

    In Indonesia, especially Jakarta have a lot of garbage strewn that can be an eyesore and also cause pollution that can carry diseases. Garbage strewn can cause many things, one of her dues is bins are overflowing due to the full so it can not accommodate the waste dumped from other people. Thus, the author created a new method for waste disposal more systematic. In creating new method requires a technology to supports, then the author makes a prototype for waste volume monitoring. By using the internet of things prototype of waste volume monitoring may give notification to the sanitary agency that waste in the trash bin needs to be disposal. In this study, conducted the design and manufactured of prototype waste volume monitoring using LinkItONE board based by Arduino and an ultrasonic sensor for appliance senses. Once the prototype is completed, evaluation in order to determine whether the prototype will function properly. The result showed that the expected function of a prototype waste volume monitoring can work well.

  17. LLE Review: Volume 63. Quarterly report, April--June 1995

    International Nuclear Information System (INIS)

    Craxton, R.S.

    1995-01-01

    This volume of the LLE Review, covering the period of April--June 1995, includes a description of the initial performance results of the upgraded OMEGA laser system. A series of acceptance tests were completed, demonstrating that all 60 beams can irradiate targets with more energy and better beam balance than was required by the Department of Energy's acceptance criteria. Other articles in this volume include a description of a novel energy measurement system used to diagnose all 60 OMEGA beams; a theoretical calculation of the cutoff wave number of the ablative Rayleigh-Taylor instability, applicable to both direct and indirect drive; a description of a new algorithm used for designing distributed phase plates that will produce super-Gaussian focal-plane irradiance profiles: a study of the photoresponse of high-T c YBCO thin films; and a description of magnetorheological finishing, a new process for optics polishing

  18. Creatine Kinase Activity Weakly Correlates to Volume Completed Following Upper Body Resistance Exercise

    Science.gov (United States)

    Machado, Marco; Willardson, Jeffrey M.; Silva, Dailson P.; Frigulha, Italo C.; Koch, Alexander J.; Souza, Sergio C.

    2012-01-01

    In the current study, we examined the relationship between serum creatine kinase (CK) activity following upper body resistance exercise with a 1- or 3-min rest between sets. Twenty men performed two sessions, each consisting of four sets with a 10-repetition maximum load. The results demonstrated significantly greater volume for the 3-min…

  19. Technical support for GEIS: radioactive waste isoltaion in geologic formations. Volume 19. Thermal analyses

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Y/OWI/TM-36/19, ''Thermal Analyses,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This volume discusses the thermal impacts of the isolated high level and spent-fuel wastes in geologic formations. A detailed account of the methodologies employed is given as well as selected results of the analyses

  20. Viability Assessment Volume 1

    International Nuclear Information System (INIS)

    1998-01-01

    1 provides introductory information about the types of waste that are destined for geologic disposal, the challenges posed by geologic disposal, a history of efforts to site a geologic repository in the US, a brief description of how DOE manages the repository program, a description of the key technical components of the repository program, and a summary of the DOE approach to identifying and prioritizing the remaining work required to complete an LA. Section 2 of Volume 1 summarizes the DOE understanding of the natural geologic and hydrologic systems of the Yucca Mountain site

  1. AAFE man-made noise experiment project. Volume 1: Introduction experiment definition and requirements

    Science.gov (United States)

    1974-01-01

    An experiment was conducted to measure and map the man-made radio frequency emanations which exist at earth orbital altitudes. The major objectives of the program are to develop a complete conceptual experiment and developmental hardware for the collection and processing of data required to produce meaningful statistics on man-made noise level variations as functions of time, frequency, and geographic location. A wide dispersion measurement receiver mounted in a spacecraft operating in a specialized orbit is used to obtain the data. A summary of the experiment designs goals and constraints is provided. The recommended orbit for the spacecraft is defined. The characteristics of the receiver and the antennas are analyzed.

  2. On complete manifolds supporting a weighted Sobolev type inequality

    International Nuclear Information System (INIS)

    Adriano, Levi; Xia Changyu

    2011-01-01

    Highlights: → We study manifolds supporting a weighted Sobolev or log-Sobolev inequality. → We investigate manifolds of asymptotically non-negative Ricci curvature. → The constant in the weighted Sobolev inequality on complete manifolds is studied. - Abstract: This paper studies the geometric and topological properties of complete open Riemannian manifolds which support a weighted Sobolev or log-Sobolev inequality. We show that the constant in the weighted Sobolev inequality on a complete open Riemannian manifold should be bigger than or equal to the optimal one on the Euclidean space of the same dimension and that a complete open manifold of asymptotically non-negative Ricci curvature supporting a weighted Sobolev inequality must have large volume growth. We also show that a complete manifold of non-negative Ricci curvature on which the log-Sobolev inequality holds is not very far from the Euclidean space.

  3. 76 FR 15308 - Completion of the Requirement To Promulgate Emission Standards

    Science.gov (United States)

    2011-03-21

    ...-2004-0505. All documents in the docket are listed in the Federal Docket Management System index at http... lawsuits filed by Sierra Club alleging that EPA has failed to complete these actions by the statutory...

  4. Is orbital volume associated with eyeball and visual cortex volume in humans?

    Science.gov (United States)

    Pearce, Eiluned; Bridge, Holly

    2013-01-01

    In humans orbital volume increases linearly with absolute latitude. Scaling across mammals between visual system components suggests that these larger orbits should translate into larger eyes and visual cortices in high latitude humans. Larger eyes at high latitudes may be required to maintain adequate visual acuity and enhance visual sensitivity under lower light levels. To test the assumption that orbital volume can accurately index eyeball and visual cortex volumes specifically in humans. Structural Magnetic Resonance Imaging (MRI) techniques are employed to measure eye and orbit (n = 88) and brain and visual cortex (n = 99) volumes in living humans. Facial dimensions and foramen magnum area (a proxy for body mass) were also measured. A significant positive linear relationship was found between (i) orbital and eyeball volumes, (ii) eyeball and visual cortex grey matter volumes and (iii) different visual cortical areas, independently of overall brain volume. In humans the components of the visual system scale from orbit to eye to visual cortex volume independently of overall brain size. These findings indicate that orbit volume can index eye and visual cortex volume in humans, suggesting that larger high latitude orbits do translate into larger visual cortices.

  5. Subsurface contamination focus area technical requirements. Volume II

    International Nuclear Information System (INIS)

    Nickelson, D.; Nonte, J.; Richardson, J.

    1996-10-01

    This is our vision, a vision that replaces the ad hoc or open-quotes delphiclose quotes method which is to get a group of open-quotes expertsclose quotes together and make decisions based upon opinion. To fulfill our vision for the Subsurface Contaminants Focus Area (SCFA), it is necessary to generate technical requirements or performance measures which are quantitative or measurable. Decisions can be supported if they are based upon requirements or performance measures which can be traced to the origin (documented) and are verifiable, i.e., prove that requirements are satisfied by inspection (show me), demonstration, analysis, monitoring, or test. The data from which these requirements are derived must also reflect the characteristics of individual landfills or plumes so that technologies that meet these requirements will necessarily work at specific sites. Other subjective factors, such as stakeholder concerns, do influence decisions. Using the requirements as a basic approach, the SCFA can depend upon objective criteria to help influence the areas of subjectivity, like the stakeholders. In the past, traceable requirements were not generated, probably because it seemed too difficult to do so. There are risks that the requirements approach will not be accepted because it is new and represents a departure from the historical paradigm

  6. Subsurface contamination focus area technical requirements. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Nickelson, D.; Nonte, J.; Richardson, J.

    1996-10-01

    This is our vision, a vision that replaces the ad hoc or {open_quotes}delphi{close_quotes} method which is to get a group of {open_quotes}experts{close_quotes} together and make decisions based upon opinion. To fulfill our vision for the Subsurface Contaminants Focus Area (SCFA), it is necessary to generate technical requirements or performance measures which are quantitative or measurable. Decisions can be supported if they are based upon requirements or performance measures which can be traced to the origin (documented) and are verifiable, i.e., prove that requirements are satisfied by inspection (show me), demonstration, analysis, monitoring, or test. The data from which these requirements are derived must also reflect the characteristics of individual landfills or plumes so that technologies that meet these requirements will necessarily work at specific sites. Other subjective factors, such as stakeholder concerns, do influence decisions. Using the requirements as a basic approach, the SCFA can depend upon objective criteria to help influence the areas of subjectivity, like the stakeholders. In the past, traceable requirements were not generated, probably because it seemed too difficult to do so. There are risks that the requirements approach will not be accepted because it is new and represents a departure from the historical paradigm.

  7. Volume-of-change cone-beam CT for image-guided surgery

    International Nuclear Information System (INIS)

    Lee, Junghoon; Stayman, J Webster; Otake, Yoshito; Schafer, Sebastian; Zbijewski, Wojciech; Khanna, A Jay; Siewerdsen, Jeffrey H; Prince, Jerry L

    2012-01-01

    C-arm cone-beam CT (CBCT) can provide intraoperative 3D imaging capability for surgical guidance, but workflow and radiation dose are the significant barriers to broad utilization. One main reason is that each 3D image acquisition requires a complete scan with a full radiation dose to present a completely new 3D image every time. In this paper, we propose to utilize patient-specific CT or CBCT as prior knowledge to accurately reconstruct the aspects of the region that have changed by the surgical procedure from only a sparse set of x-rays. The proposed methods consist of a 3D–2D registration between the prior volume and a sparse set of intraoperative x-rays, creating digitally reconstructed radiographs (DRRs) from the registered prior volume, computing difference images by subtracting DRRs from the intraoperative x-rays, a penalized likelihood reconstruction of the volume of change (VOC) from the difference images, and finally a fusion of VOC reconstruction with the prior volume to visualize the entire surgical field. When the surgical changes are local and relatively small, the VOC reconstruction involves only a small volume size and a small number of projections, allowing less computation and lower radiation dose than is needed to reconstruct the entire surgical field. We applied this approach to sacroplasty phantom data obtained from a CBCT test bench and vertebroplasty data with a fresh cadaver acquired from a C-arm CBCT system with a flat-panel detector. The VOCs were reconstructed from a varying number of images (10–66 images) and compared to the CBCT ground truth using four different metrics (mean squared error, correlation coefficient, structural similarity index and perceptual difference model). The results show promising reconstruction quality with structural similarity to the ground truth close to 1 even when only 15–20 images were used, allowing dose reduction by the factor of 10–20. (paper)

  8. [Complete atrioventricular block in Duchenne muscular dystrophy].

    Science.gov (United States)

    Kuru, Satoshi; Tanahashi, Tamotsu; Matsumoto, Shinjirou; Kitamura, Tetsuya; Konagaya, Masaaki

    2012-01-01

    We report a case of complete atrioventricular (AV) block in a 40-year-old patient with Duchenne muscular dystrophy (DMD). While he was bed-ridden and required mechanical ventilation, his cardiac involvement was mild. He had the deletion of exon 45-52 in the dystrophin gene. He underwent transient complete AV block and came to require pacemaker implantation due to recurrence of complete AV block ten days after the first attack. Electrophysiological study revealed mild prolonged AH and HV interval. Although DMD patients with AV block have been rarely reported so far, attention should be paid to AV block for patients who prolonged their lives.

  9. Clinical comparison of masticatory performance and electromyographic activity of patients with complete dentures, overdentures, and natural teeth.

    Science.gov (United States)

    Rissin, L; House, J E; Manly, R S; Kapur, K K

    1978-05-01

    In this study, which is the first of its kind, it has been shown that overdenture patients, when compared to complete denture patients, while chewing a test food for a constant number of strokes, expended an equivalent amount of muscle effort, chewed more slowly and efficiently, and evidenced significantly better masticatory performance by producing an increased volume of fine test food particles. These findings provide a sound justification for the extra effort required to retain some natural teeth to provide overdenture services to patients. The fact that patients can masticate food more efficiently with overdentures than with complete dentures justifies the increased cost and time involved in their construction. The longitudinal effects that overdentures have on the basic physiopathologic processed involved in the progression of ridge resorption and the advantages of maintaining periodontal proprioception also should be studied.

  10. Volume definition system for treatment planning

    International Nuclear Information System (INIS)

    Alakuijala, Jyrki; Pekkarinen, Ari; Puurunen, Harri

    1997-01-01

    volume definition process dramatically. Its true 3D nature allows the algorithm to find the regions quickly with high accuracy. The competitive volume growing requires only a small amount of user input for initial seeding. The simultaneous growing of multiple segments mitigates volume leaking, which is a major problem in normal region growing. The automatic tool finds body outline, air, and couch reliably in 30 s for a volume image of 30 slices. Other algorithms are almost interactive. CTV interpolation is an excellent feature for defining a CTV spanning over several slices. Real time verification in 2D and 3D visualization support the operator and thus speed up the contouring process. Conclusions: The contouring process requires a rich set of tools to comply with the multi-faceted requirements of volume definition. Body, specific anatomic volumes and target are best defined using a set of tools specifically built for that purpose. The execution speed of both the algorithms and visualization is very important for operator satisfaction

  11. The Complete Semiconductor Transistor and Its Incomplete Forms

    International Nuclear Information System (INIS)

    Jie Binbin; Sah, C.-T.

    2009-01-01

    This paper describes the definition of the complete transistor. For semiconductor devices, the complete transistor is always bipolar, namely, its electrical characteristics contain both electron and hole currents controlled by their spatial charge distributions. Partially complete or incomplete transistors, via coined names or/and designed physical geometries, included the 1949 Shockley p/n junction transistor (later called Bipolar Junction Transistor, BJT), the 1952 Shockley unipolar 'field-effect' transistor (FET, later called the p/n Junction Gate FET or JGFET), as well as the field-effect transistors introduced by later investigators. Similarities between the surface-channel MOS-gate FET (MOSFET) and the volume-channel BJT are illustrated. The bipolar currents, identified by us in a recent nanometer FET with 2-MOS-gates on thin and nearly pure silicon base, led us to the recognition of the physical makeup and electrical current and charge compositions of a complete transistor and its extension to other three or more terminal signal processing devices, and also the importance of the terminal contacts.

  12. NSF- and SNARE-mediated membrane fusion is required for nuclear envelope formation and completion of nuclear pore complex assembly in Xenopus laevis egg extracts.

    Science.gov (United States)

    Baur, Tina; Ramadan, Kristijan; Schlundt, Andreas; Kartenbeck, Jürgen; Meyer, Hemmo H

    2007-08-15

    Despite the progress in understanding nuclear envelope (NE) reformation after mitosis, it has remained unclear what drives the required membrane fusion and how exactly this is coordinated with nuclear pore complex (NPC) assembly. Here, we show that, like other intracellular fusion reactions, NE fusion in Xenopus laevis egg extracts is mediated by SNARE proteins that require activation by NSF. Antibodies against Xenopus NSF, depletion of NSF or the dominant-negative NSF(E329Q) variant specifically inhibited NE formation. Staging experiments further revealed that NSF was required until sealing of the envelope was completed. Moreover, excess exogenous alpha-SNAP that blocks SNARE function prevented membrane fusion and caused accumulation of non-flattened vesicles on the chromatin surface. Under these conditions, the nucleoporins Nup107 and gp210 were fully recruited, whereas assembly of FxFG-repeat-containing nucleoporins was blocked. Together, we define NSF- and SNARE-mediated membrane fusion events as essential steps during NE formation downstream of Nup107 recruitment, and upstream of membrane flattening and completion of NPC assembly.

  13. Multi-site, multi-country evaluation of analytical and operational performance of a low-mid volume chemiluminescent immunoassay analyzer.

    Science.gov (United States)

    De Keijzer, M H; Perkins, S; Motta, V; Morelli, D; Cristol, J P; Dupuy, A M; Hong, Y; Watanabe, S; Waerdt, C; Grunewald, R W

    2009-01-01

    A new automated immunoassay low-mid volume (beta-hCG, BNP, and CK-MB) and the time required to complete workloads of 50 and 100 tests with a mixture of 75% routine tests and 25% stat tests was also evaluated. Total precision was typically market and in use for an existing high volume immunoassay system. Stat turn around times were consistent with the fixed analytical time of 15.6 minutes and met the expectations of the laboratories. Measured test throughput ranged from 47 - 54 tests per hour and demonstrated that the analyzer was fit for the intended purpose of supporting a laboratory that performs suitable for use.

  14. The use of phase sequence image sets to reconstruct the total volume occupied by a mobile lung tumor

    International Nuclear Information System (INIS)

    Gagne, Isabelle M.; Robinson, Don M.; Halperin, Ross; Roa, Wilson

    2005-01-01

    The use of phase sequence image (PSI) sets to reveal the total volume occupied by a mobile target is presented. Isocontrast composite clinical target volumes (CCTVs) may be constructed from PSI sets in order to reveal the total volume occupied by a mobile target during the course of its travel. The ability of the CCTV technique to properly account for target motion is demonstrated by comparison to contours of the true total volume occupied (TVO) for a number of experimental phantom geometries. Finally, using real patient data, the clinical utility of the CCTV technique to properly account for internal tumor motion while minimizing the volume of healthy lung tissue irradiated is assessed by comparison to the standard approach of applying safety margins. Results of the phantom study reveal that CCTV cross sections constructed at the 20% isocontrast level yield good agreement with the total cross sections (TXO) of mobile targets. These CCTVs conform well to the TVOs of the moving targets examined whereby the addition of small uniform margins ensures complete circumscription of the TVO with the inclusion of minimal amounts of surrounding external volumes. The CCTV technique is seen to be clearly superior to the common practice of the addition of safety margins to individual CTV contours in order to account for internal target motion. Margins required with the CCTV technique are eight to ten times smaller than those required with individual CTVs

  15. Effects of Anti-VEGF on Predicted Antibody Biodistribution: Roles of Vascular Volume, Interstitial Volume, and Blood Flow

    Science.gov (United States)

    Boswell, C. Andrew; Ferl, Gregory Z.; Mundo, Eduardo E.; Bumbaca, Daniela; Schweiger, Michelle G.; Theil, Frank-Peter; Fielder, Paul J.; Khawli, Leslie A.

    2011-01-01

    Background The identification of clinically meaningful and predictive models of disposition kinetics for cancer therapeutics is an ongoing pursuit in drug development. In particular, the growing interest in preclinical evaluation of anti-angiogenic agents alone or in combination with other drugs requires a complete understanding of the associated physiological consequences. Methodology/Principal Findings Technescan™ PYP™, a clinically utilized radiopharmaceutical, was used to measure tissue vascular volumes in beige nude mice that were naïve or administered a single intravenous bolus dose of a murine anti-vascular endothelial growth factor (anti-VEGF) antibody (10 mg/kg) 24 h prior to assay. Anti-VEGF had no significant effect (p>0.05) on the fractional vascular volumes of any tissues studied; these findings were further supported by single photon emission computed tomographic imaging. In addition, apart from a borderline significant increase (p = 0.048) in mean hepatic blood flow, no significant anti-VEGF-induced differences were observed (p>0.05) in two additional physiological parameters, interstitial fluid volume and the organ blood flow rate, measured using indium-111-pentetate and rubidium-86 chloride, respectively. Areas under the concentration-time curves generated by a physiologically-based pharmacokinetic model changed substantially (>25%) in several tissues when model parameters describing compartmental volumes and blood flow rates were switched from literature to our experimentally derived values. However, negligible changes in predicted tissue exposure were observed when comparing simulations based on parameters measured in naïve versus anti-VEGF-administered mice. Conclusions/Significance These observations may foster an enhanced understanding of anti-VEGF effects in murine tissues and, in particular, may be useful in modeling antibody uptake alone or in combination with anti-VEGF. PMID:21436893

  16. Reachable volume RRT

    KAUST Repository

    McMahon, Troy

    2015-05-01

    © 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

  17. Reachable volume RRT

    KAUST Repository

    McMahon, Troy; Thomas, Shawna; Amato, Nancy M.

    2015-01-01

    © 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

  18. Savannah River Site mixed waste Proposed Site Treatment Plan (PSTP). Volumes 1 and 2 and reference document: Revision 2

    International Nuclear Information System (INIS)

    Helmich, E.; Noller, D.K.; Wierzbicki, K.S.; Bailey, L.L.

    1995-01-01

    The DOE is required by the Resource Conservation and Recovery Act to prepare site treatment plans describing the development of treatment capacities and technologies for treating mixed waste. This proposed plan contains Savannah River Site's preferred options and schedules for constructing new facilities, and otherwise obtaining treatment for mixed wastes. The proposed plan consists of 2 volumes. Volume 1, Compliance Plan, identifies the capacity to be developed and the schedules as required. Volume 2, Background, provides a detailed discussion of the preferred options with technical basis, plus a description of the specific waste streams. Chapters are: Introduction; Methodology; Mixed low level waste streams; Mixed transuranic waste; High level waste; Future generation of mixed waste streams; Storage; Process for evaluation of disposal issues in support of the site treatment plans discussions; Treatment facilities and treatment technologies; Offsite waste streams for which SRS treatment is the Preferred Option (Naval reactor wastes); Summary information; and Acronyms and glossary. This revision does not contain the complete revised report, but only those pages that have been revised

  19. The Complete Local Volume Groups Sample - I. Sample selection and X-ray properties of the high-richness subsample

    Science.gov (United States)

    O'Sullivan, Ewan; Ponman, Trevor J.; Kolokythas, Konstantinos; Raychaudhury, Somak; Babul, Arif; Vrtilek, Jan M.; David, Laurence P.; Giacintucci, Simona; Gitti, Myriam; Haines, Chris P.

    2017-12-01

    We present the Complete Local-Volume Groups Sample (CLoGS), a statistically complete optically selected sample of 53 groups within 80 Mpc. Our goal is to combine X-ray, radio and optical data to investigate the relationship between member galaxies, their active nuclei and the hot intra-group medium (IGM). We describe sample selection, define a 26-group high-richness subsample of groups containing at least four optically bright (log LB ≥ 10.2 LB⊙) galaxies, and report the results of XMM-Newton and Chandra observations of these systems. We find that 14 of the 26 groups are X-ray bright, possessing a group-scale IGM extending at least 65 kpc and with luminosity >1041 erg s-1, while a further three groups host smaller galaxy-scale gas haloes. The X-ray bright groups have masses in the range M500 ≃ 0.5-5 × 1013 M⊙, based on system temperatures of 0.4-1.4 keV, and X-ray luminosities in the range 2-200 × 1041 erg s-1. We find that ∼53-65 per cent of the X-ray bright groups have cool cores, a somewhat lower fraction than found by previous archival surveys. Approximately 30 per cent of the X-ray bright groups show evidence of recent dynamical interactions (mergers or sloshing), and ∼35 per cent of their dominant early-type galaxies host active galactic nuclei with radio jets. We find no groups with unusually high central entropies, as predicted by some simulations, and confirm that CLoGS is in principle capable of detecting such systems. We identify three previously unrecognized groups, and find that they are either faint (LX, R500 < 1042 erg s-1) with no concentrated cool core, or highly disturbed. This leads us to suggest that ∼20 per cent of X-ray bright groups in the local universe may still be unidentified.

  20. Nineteenth International Cosmic Ray Conference papers. General index, volume 10

    International Nuclear Information System (INIS)

    Jones, F.C.

    1986-07-01

    These volumes contain papers submitted for presentation at the 19th International Cosmic Ray Conference held on the campus of the University of California, San Diego, in La Jolla, CA, Aug. 11-23, 1985. The present volume contains a complete author index for volumes 1 through 9 and a list of the names and addresses of all those who attended the conference

  1. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 23. Environmental effluent analyses

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Y/OWI/TM-36/23, ''Environmental Effluent Analysis,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Drat Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This volume discusses the releases to the environment of radioactive and non-radioactive materials that arise during facility construction and waste handling operations, as well as releases that could occur in the event of an operational accident. The results of the analyses are presented along with a detailed description of the analytical methodologies employed

  2. Complete atrioventricular canal.

    Science.gov (United States)

    Calabrò, Raffaele; Limongelli, Giuseppe

    2006-04-05

    Complete atrioventricular canal (CAVC), also referred to as complete atrioventricular septal defect, is characterised by an ostium primum atrial septal defect, a common atrioventricular valve and a variable deficiency of the ventricular septum inflow. CAVC is an uncommon congenital heart disease, accounting for about 3% of cardiac malformations. Atrioventricular canal occurs in two out of every 10,000 live births. Both sexes are equally affected and a striking association with Down syndrome was found. Depending on the morphology of the superior leaflet of the common atrioventricular valve, 3 types of CAVC have been delineated (type A, B and C, according to Rastelli's classification). CAVC results in a significant interatrial and interventricular systemic-to-pulmonary shunt, thus inducing right ventricular pressure and volume overload and pulmonary hypertension. It becomes symptomatic in infancy due to congestive heart failure and failure to thrive. Diagnosis of CAVC might be suspected from electrocardiographic and chest X-ray findings. Echocardiography confirms it and gives anatomical details. Over time, pulmonary hypertension becomes irreversible, thus precluding the surgical therapy. This is the reason why cardiac catheterisation is not mandatory in infants (less than 6 months) but is indicated in older patients if irreversible pulmonary hypertension is suspected. Medical treatment (digitalis, diuretics, vasodilators) plays a role only as a bridge toward surgery, usually performed between the 3rd and 6th month of life.

  3. Complete atrioventricular canal

    Directory of Open Access Journals (Sweden)

    Limongelli Giuseppe

    2006-04-01

    Full Text Available Abstract Complete atrioventricular canal (CAVC, also referred to as complete atrioventricular septal defect, is characterised by an ostium primum atrial septal defect, a common atrioventricular valve and a variable deficiency of the ventricular septum inflow. CAVC is an uncommon congenital heart disease, accounting for about 3% of cardiac malformations. Atrioventricular canal occurs in two out of every 10,000 live births. Both sexes are equally affected and a striking association with Down syndrome was found. Depending on the morphology of the superior leaflet of the common atrioventricular valve, 3 types of CAVC have been delineated (type A, B and C, according to Rastelli's classification. CAVC results in a significant interatrial and interventricular systemic-to-pulmonary shunt, thus inducing right ventricular pressure and volume overload and pulmonary hypertension. It becomes symptomatic in infancy due to congestive heart failure and failure to thrive. Diagnosis of CAVC might be suspected from electrocardiographic and chest X-ray findings. Echocardiography confirms it and gives anatomical details. Over time, pulmonary hypertension becomes irreversible, thus precluding the surgical therapy. This is the reason why cardiac catheterisation is not mandatory in infants (less than 6 months but is indicated in older patients if irreversible pulmonary hypertension is suspected. Medical treatment (digitalis, diuretics, vasodilators plays a role only as a bridge toward surgery, usually performed between the 3rd and 6th month of life.

  4. A flexible and accurate digital volume correlation method applicable to high-resolution volumetric images

    Science.gov (United States)

    Pan, Bing; Wang, Bo

    2017-10-01

    Digital volume correlation (DVC) is a powerful technique for quantifying interior deformation within solid opaque materials and biological tissues. In the last two decades, great efforts have been made to improve the accuracy and efficiency of the DVC algorithm. However, there is still a lack of a flexible, robust and accurate version that can be efficiently implemented in personal computers with limited RAM. This paper proposes an advanced DVC method that can realize accurate full-field internal deformation measurement applicable to high-resolution volume images with up to billions of voxels. Specifically, a novel layer-wise reliability-guided displacement tracking strategy combined with dynamic data management is presented to guide the DVC computation from slice to slice. The displacements at specified calculation points in each layer are computed using the advanced 3D inverse-compositional Gauss-Newton algorithm with the complete initial guess of the deformation vector accurately predicted from the computed calculation points. Since only limited slices of interest in the reference and deformed volume images rather than the whole volume images are required, the DVC calculation can thus be efficiently implemented on personal computers. The flexibility, accuracy and efficiency of the presented DVC approach are demonstrated by analyzing computer-simulated and experimentally obtained high-resolution volume images.

  5. Oracle Goldengate 11g complete cookbook

    CERN Document Server

    Gupta, Ankur

    2013-01-01

    Oracle Goldengate 11g Complete Cookbook follows the Cookbook style. Each recipe provides step by step instructions with various examples and scripts. This book provides the necessary information to successfully complete most of the possible administration tasks.Oracle Goldengate 11g Complete Cookbook is aimed at Database Administrators, Architects, and Middleware Administrators who are keen to know more about Oracle Goldengate. Whether you are handling Goldengate environments on a day-to-day basis, or using it just for migration, this book provides the necessary information required to success

  6. Mars power system concept definition study. Volume 2: Appendices

    Science.gov (United States)

    Littman, Franklin D.

    1994-01-01

    This report documents the work performed by Rockwell International's Rocketdyne Division on NASA Contract No. NAS3-25808 (Task Order No. 16) entitled 'Mars Power System Definition Study'. This work was performed for NASA's Lewis Research Center (LeRC). The report is divided into two volumes as follows: Volume 1 - Study Results; and Volume 2 - Appendices. The results of the power system characterization studies, operations studies, and technology evaluations are summarized in Volume 1. The appendices include complete, standalone technology development plans for each candidate power system that was investigated.

  7. Loop quantum cosmology of the Bianchi I model: complete quantization

    International Nuclear Information System (INIS)

    Martín-Benito, M; Garay, L J; Mena Marugán, G A; Wilson-Ewing, E

    2012-01-01

    We complete the canonical quantization of the vacuum Bianchi I model within the improved dynamics scheme of loop quantum cosmology, characterizing the Hilbert structure of the physical states and providing a complete set of observables acting on them. In order to achieve this task, it has been essential to determine the structure of the separable superselection sectors that arise owing to the polymeric quantization, and to prove that the initial value problem obtained when regarding the Hamiltonian constraint as an evolution equation, interpreting the volume as the evolution parameter, is well-posed.

  8. Three surgical planes identified in laparoscopic complete mesocolic excision for right-sided colon cancer.

    Science.gov (United States)

    Zhu, Da-Jian; Chen, Xiao-Wu; OuYang, Man-Zhao; Lu, Yan

    2016-01-12

    Complete mesocolic excision provides a correct anatomical plane for colon cancer surgery. However, manifestation of the surgical plane during laparoscopic complete mesocolic excision versus in computed tomography images remains to be examined. Patients who underwent laparoscopic complete mesocolic excision for right-sided colon cancer underwent an abdominal computed tomography scan. The spatial relationship of the intraoperative surgical planes were examined, and then computed tomography reconstruction methods were applied. The resulting images were analyzed. In 44 right-sided colon cancer patients, the surgical plane for laparoscopic complete mesocolic excision was found to be composed of three surgical planes that were identified by computed tomography imaging with cross-sectional multiplanar reconstruction, maximum intensity projection, and volume reconstruction. For the operations performed, the mean bleeding volume was 73±32.3 ml and the mean number of harvested lymph nodes was 22±9.7. The follow-up period ranged from 6-40 months (mean 21.2), and only two patients had distant metastases. The laparoscopic complete mesocolic excision surgical plane for right-sided colon cancer is composed of three surgical planes. When these surgical planes were identified, laparoscopic complete mesocolic excision was a safe and effective procedure for the resection of colon cancer.

  9. A method for determining the completeness of fuel combustion

    Energy Technology Data Exchange (ETDEWEB)

    Tavger, M.D.; Chepkin, V.M.; Gruzdev, V.N.; Talantov, A.V.

    1982-01-01

    The current of conductivity (ionization) of gaseous combustion products, which forms with feeding of electric voltage to a special probe, is proposed for determining the completeness of fuel combustion. Here, the charged particles are formed from substances which form in the intermediate stages of the combustion reaction. The volume of charged particles is proportional to the volume of the intermediate substances, whose presence attests to the incompleteness of the combustion reaction. The fullness of fuel combustion is determined from a formula which includes the stoichiometric coefficient, a gas constant, the energy of activation, the characteristics of the chemical activity of the intermediate substances, the coefficient of air excess, the temperature of the combustion products and the conductivity current.

  10. Rapid assay for cell age response to radiation by electronic volume flow cell sorting

    International Nuclear Information System (INIS)

    Freyer, J.P.; Wilder, M.E.; Raju, M.R.

    1987-01-01

    A new technique is described for measuring cell survival as a function of cell cycle position using flow cytometric cell sorting on the basis of electronic volume signals. Sorting of cells into different cell age compartments is demonstrated for three different cell lines commonly used in radiobiological research. Using flow cytometric DNA content analysis and [ 3 H]thymidine autoradiography of the sorted cell populations, it is demonstrated that resolution of the age compartment separation is as good as or better than that reported for other cell synchronizing techniques. Variation in cell survival as a function of position in the cell cycle after a single dose of radiation as measured by volume cell sorting is similar to that determined by other cell synchrony techniques. Advantages of this method include: (1) no treatment of the cells is required, thus, this method is noncytotoxic; (2) no cell cycle progression is needed to obtain different cell age compartments; (3) the cell population can be held in complete growth medium at any desired temperature during sorting; (4) a complete radiation age - response assay can be plated in 2 h. Applications of this method are discussed, along with some technical limitations. (author)

  11. WordPress 3.7 complete

    CERN Document Server

    Król, Karol

    2013-01-01

    WordPress 3.5 Complete: Third Edition is a comprehensive and step-by-step tutorial packed with screenshots and examples to make it easy and quick to pick it up.This WordPress book is a guide to WordPress for online publishers and web developers. If you are new to blogging and want to create your own blog or website from scratch, then ""WordPress 3.5 Complete: Third Edition"" is for you. No prior knowledge of HTML/CSS or PHP is required.

  12. Flow dynamics of volume-heated boiling pools

    International Nuclear Information System (INIS)

    Ginsberg, T.; Jones, O.C.; Chen, J.C.

    1979-01-01

    Safety analyses of fast breeder reactors require understanding of the two-phase fluid dynamic and heat transfer characteristics of volume-heated boiling pool systems. Design of direct contact three-phase boilers, of practical interest in the chemical industries also requires understanding of the fundamental two-phase flow and heat transfer behavior of volume boiling systems. Several experiments have been recently reported relevant to the boundary heat-loss mechanisms of boiling pool systems. Considerably less is known about the two-phase fluid dynamic behavior of such systems. This paper describes an experimental investigation of the steady-state flow dynamics of volume-heated boiling pool systems

  13. Compendium in astronomy a volume dedicated to professor John Xanthakis on the occasion of completing twenty-five years of scientific activities as fellow of the National Academy of Athens

    CERN Document Server

    Theocaris, Pericles; Mavridis, L

    1982-01-01

    When we first approached some colleagues allover the world to sound them about a volume dedicated to Professor John Xanthakis on the occasion of completing twenty-five years of scientific activities as fellow of the National Academy of Athens, any possible doubts as to the feasibility of the project were quickly dispelled by their warm and encouraging response. In a short time 50 authors from 15 countries, coming from a wide range of Professor Xanthakis' immediate colleagues, pupils and friends joined to produce the 36 contributions included in this volume. Some of those who where originally approached found themselves un­ able to contribute, because of the time-limit necessarily imposed. Happi­ ly, they were only few in number, and we should like to record our grat­ itude to them for their good wishes for the success of the venture. Their warm words were among the many sources of inspiring encouragement extended to us.

  14. Similarity problems and completely bounded maps

    CERN Document Server

    Pisier, Gilles

    2001-01-01

    These notes revolve around three similarity problems, appearing in three different contexts, but all dealing with the space B(H) of all bounded operators on a complex Hilbert space H. The first one deals with group representations, the second one with C* -algebras and the third one with the disc algebra. We describe them in detail in the introduction which follows. This volume is devoted to the background necessary to understand these three problems, to the solutions that are known in some special cases and to numerous related concepts, results, counterexamples or extensions which their investigation has generated. While the three problems seem different, it is possible to place them in a common framework using the key concept of "complete boundedness", which we present in detail. Using this notion, the three problems can all be formulated as asking whether "boundedness" implies "complete boundedness" for linear maps satisfying certain additional algebraic identities. Two chapters have been added on the HALMO...

  15. Soluble Model Fluids with Complete Scaling and Yang-Yang Features

    Science.gov (United States)

    Cerdeiriña, Claudio A.; Orkoulas, Gerassimos; Fisher, Michael E.

    2016-01-01

    Yang-Yang (YY) and singular diameter critical anomalies arise in exactly soluble compressible cell gas (CCG) models that obey complete scaling with pressure mixing. Thus, on the critical isochore ρ =ρc , C˜ μ≔-T d2μ /d T2 diverges as |t |-α when t ∝T -Tc→0- while ρd-ρc˜|t |2β where ρd(T )=1/2 [ρliq+ρgas] . When the discrete local CCG cell volumes fluctuate freely, the YY ratio Rμ=C˜μ/CV may take any value -∞ 0 . More general decorated CCGs, including "hydrogen bonding" water models, illuminate energy-volume coupling as relevant to Rμ.

  16. Measuring Blood Glucose Concentrations in Photometric Glucometers Requiring Very Small Sample Volumes.

    Science.gov (United States)

    Demitri, Nevine; Zoubir, Abdelhak M

    2017-01-01

    Glucometers present an important self-monitoring tool for diabetes patients and, therefore, must exhibit high accuracy as well as good usability features. Based on an invasive photometric measurement principle that drastically reduces the volume of the blood sample needed from the patient, we present a framework that is capable of dealing with small blood samples, while maintaining the required accuracy. The framework consists of two major parts: 1) image segmentation; and 2) convergence detection. Step 1 is based on iterative mode-seeking methods to estimate the intensity value of the region of interest. We present several variations of these methods and give theoretical proofs of their convergence. Our approach is able to deal with changes in the number and position of clusters without any prior knowledge. Furthermore, we propose a method based on sparse approximation to decrease the computational load, while maintaining accuracy. Step 2 is achieved by employing temporal tracking and prediction, herewith decreasing the measurement time, and, thus, improving usability. Our framework is tested on several real datasets with different characteristics. We show that we are able to estimate the underlying glucose concentration from much smaller blood samples than is currently state of the art with sufficient accuracy according to the most recent ISO standards and reduce measurement time significantly compared to state-of-the-art methods.

  17. Quantum space and quantum completeness

    Science.gov (United States)

    Jurić, Tajron

    2018-05-01

    Motivated by the question whether quantum gravity can "smear out" the classical singularity we analyze a certain quantum space and its quantum-mechanical completeness. Classical singularity is understood as a geodesic incompleteness, while quantum completeness requires a unique unitary time evolution for test fields propagating on an underlying background. Here the crucial point is that quantum completeness renders the Hamiltonian (or spatial part of the wave operator) to be essentially self-adjoint in order to generate a unique time evolution. We examine a model of quantum space which consists of a noncommutative BTZ black hole probed by a test scalar field. We show that the quantum gravity (noncommutative) effect is to enlarge the domain of BTZ parameters for which the relevant wave operator is essentially self-adjoint. This means that the corresponding quantum space is quantum complete for a larger range of BTZ parameters rendering the conclusion that in the quantum space one observes the effect of "smearing out" the singularity.

  18. Three-Dimensional Incompressible Navier-Stokes Flow Computations about Complete Configurations Using a Multiblock Unstructured Grid Approach

    Science.gov (United States)

    Sheng, Chunhua; Hyams, Daniel G.; Sreenivas, Kidambi; Gaither, J. Adam; Marcum, David L.; Whitfield, David L.

    2000-01-01

    A multiblock unstructured grid approach is presented for solving three-dimensional incompressible inviscid and viscous turbulent flows about complete configurations. The artificial compressibility form of the governing equations is solved by a node-based, finite volume implicit scheme which uses a backward Euler time discretization. Point Gauss-Seidel relaxations are used to solve the linear system of equations at each time step. This work employs a multiblock strategy to the solution procedure, which greatly improves the efficiency of the algorithm by significantly reducing the memory requirements by a factor of 5 over the single-grid algorithm while maintaining a similar convergence behavior. The numerical accuracy of solutions is assessed by comparing with the experimental data for a submarine with stem appendages and a high-lift configuration.

  19. Integrated Association Rules Complete Hiding Algorithms

    Directory of Open Access Journals (Sweden)

    Mohamed Refaat Abdellah

    2017-01-01

    Full Text Available This paper presents database security approach for complete hiding of sensitive association rules by using six novel algorithms. These algorithms utilize three new weights to reduce the needed database modifications and support complete hiding, as well as they reduce the knowledge distortion and the data distortions. Complete weighted hiding algorithms enhance the hiding failure by 100%; these algorithms have the advantage of performing only a single scan for the database to gather the required information to form the hiding process. These proposed algorithms are built within the database structure which enables the sanitized database to be generated on run time as needed.

  20. Fusion Engineering Device. Volume V. Technology R and D requirements for construction

    International Nuclear Information System (INIS)

    1981-10-01

    This volume covers the following areas: (1) nuclear systems, (2) auxiliary heating, (3) magnet systems, (4) remote maintenance, (5) fueling, (6) diagnostics, instrumentation, information and control, and (7) safety and environment

  1. NPR hazards review: (Phase 1, Production only appendixes). Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Miller, N.R.; Trumble, R.E.

    1962-08-15

    The NPR Hazards Review is being issued in a series of volumes. Volume 1, which has already been published, was of the nature of an expanded summary. It included the results of hazards analyses with some explanatory material to put the results in context. Volume 2 presents results of reviews made after the preparation of Volume 1. It also contains supporting material and details not included in Volume 1. Volumes 1 and 2 together provide a nearly complete ``Design Hazards Review of the NPR.`` However, certain remaining problems still exist and are to be the subject of a continuing R&D program. These problems and programs are discussed in Appendix H. Neither Volume 1 nor Volume 2 treat operational aspects of reactor hazards in detail. This area of concern will be the primary subject of a third volume of the NPR Hazards Review. This third volume, to be prepared and issued at a later date, may also contain information supplementing Volumes 1 and 2.

  2. Requirements Development Issues for Advanced Life Support Systems: Solid Waste Management

    Science.gov (United States)

    Levri, Julie A.; Fisher, John W.; Alazraki, Michael P.; Hogan, John A.

    2002-01-01

    Long duration missions pose substantial new challenges for solid waste management in Advanced Life Support (ALS) systems. These possibly include storing large volumes of waste material in a safe manner, rendering wastes stable or sterilized for extended periods of time, and/or processing wastes for recovery of vital resources. This is further complicated because future missions remain ill-defined with respect to waste stream quantity, composition and generation schedule. Without definitive knowledge of this information, development of requirements is hampered. Additionally, even if waste streams were well characterized, other operational and processing needs require clarification (e.g. resource recovery requirements, planetary protection constraints). Therefore, the development of solid waste management (SWM) subsystem requirements for long duration space missions is an inherently uncertain, complex and iterative process. The intent of this paper is to address some of the difficulties in writing requirements for missions that are not completely defined. This paper discusses an approach and motivation for ALS SWM requirements development, the characteristics of effective requirements, and the presence of those characteristics in requirements that are developed for uncertain missions. Associated drivers for life support system technological capability are also presented. A general means of requirements forecasting is discussed, including successive modification of requirements and the need to consider requirements integration among subsystems.

  3. Scoping studies to reduce ICPP high-level radioactive waste volumes for final disposal

    International Nuclear Information System (INIS)

    Knecht, D.A.; Berreth, J.R.; Chipman, N.A.; Cole, H.S.; Geczi, L.S.; Kerr, W.B.; Staples, B.A.

    1985-08-01

    This report presents the results of scoping studies carried out to determine the feasibility of the following candidate options to reduce high-level waste volume: (1) low-fluoride, low-volume glass, (2) glass-ceramic and ceramic, (3) Modified Zirflex, (4) inerts removal by neutralization, and (5) modified Fluorinel processes. The results of the scoping studies show that the glass-ceramic/ceramic waste forms and neutralization process with potential HLW volume reductions ranging from 60 to 80% appear feasible, based on laboratory-scale tests. The presently used Fluorinel process modified by reducing HF usage also appears to be feasible and could result in up to a 10% potential volume reduction. If the current process start-up tests verify the practicality, reduced HF usage will be implemented. The low-volume glass and Modified Zirflex processes may also be feasible, based on laboratory tests, but would require significantly more process development and/or modifications and could result in only a 20 to 30% potential volume reduction. Based on these scoping studies, it is recommended that (1) the glass-ceramic/ceramic and neutralization processes be developed further, (2) reduced HF use for the Modified Fluorinel process be implemented as soon as practical and other options reducing chemical usage for criticality control be evaluated, (3) basic development for the glass process be continued as a back-up technology, and (4) laboratory-scale radioactive fuel dissolution testing for the Modified Zirflex process be completed with further process development discontinued unless needed in the future

  4. Prediction of shale prospectivity from seismically-derived reservoir and completion qualities: Application to a shale-gas field, Horn River Basin, Canada

    Science.gov (United States)

    Mo, Cheol Hoon; Lee, Gwang H.; Jeoung, Taek Ju; Ko, Kyung Nam; Kim, Ki Soo; Park, Kyung-sick; Shin, Chang Hoon

    2018-04-01

    Prospective shale plays require a combination of good reservoir and completion qualities. Total organic carbon (TOC) is an important reservoir quality and brittleness is the most critical condition for completion quality. We analyzed seismically-derived brittleness and TOC to investigate the prospectivity of the Horn River Group shale (the Muskwa, Otter Park, Evie shales) of a shale-gas field in the western Horn River Basin, British Columbia, Canada. We used the λρ-μρ brittleness template, constructed from the mineralogy-based brittleness index (MBI) and elastic logs from two wells, to convert the λρ and μρ volumes from prestack seismic inversion to the volume for the brittleness petrotypes (most brittle, intermediate, and least brittle). The probability maps of the most brittle petrotype for the three shales were generated from Bayesian classification, based on the λρ-μρ template. The relationship between TOC and P-wave and S-wave velocity ratio (VP/VS) at the wells allowed the conversion of the VP/VS volume from prestack inversion to the TOC volume, which in turn was used to construct the TOC maps for the three shales. Increased TOC is correlated with high brittleness, contrasting with the commonly-held understanding. Therefore, the prospectivity of the shales in the study area can be represented by high brittleness and increased TOC. We propose a shale prospectivity index (SPI), computed by the arithmetic average of the normalized probability of the most brittle petrotype and the normalized TOC. The higher SPI corresponds to higher production rates in the Muskwa and Evie shales. The areas of the highest SPI have not been fully tested. The future drilling should be focused on these areas to increase the economic viability of the field.

  5. C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 1: Concepts of Use, Initial System Requirements, Architecture, and AeroMACS Design Considerations

    Science.gov (United States)

    Hall, Edward; Isaacs, James; Henriksen, Steve; Zelkin, Natalie

    2011-01-01

    This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I (this document) is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

  6. Numerical dissipation and dispersion of the homogenenous and complete flux schemes

    NARCIS (Netherlands)

    Thije Boonkkamp, ten J.H.M.; Anthonissen, M.J.H.

    2014-01-01

    We analyse numerical dissipation and dispersion of the homogeneous ¿ux (HF) and complete ¿ux (CF) schemes, ¿nite volume methods introduced in [1]. To that purpose we derive the modi¿ed equation of both schemes. We show that the HF scheme suffers from numerical diffusion for dominant advection, which

  7. Economic evaluation of volume reduction for Defense transuranic waste

    International Nuclear Information System (INIS)

    Brown, C.M.

    1982-03-01

    The economics of volume reduction of retrievably stored and newly generated DOE transuranic wastes are evaluated by comparing the costs of reduction of the wastes with the savings possible in transportation and disposal. A general approach to the comparison of TRU waste volume reduction costs and cost savings is developed, an initial set of cost data is established, conclusions to support selecting technologies and facilities for the disposal of DOE transuranic waste are developed. Section I outlines the analysis which considers seven types of volume reduction from incineration and compaction of combustibles to compaction, size reduction, shredding, melting, and decontamination of metals. The study considers the volume reduction of contact-handled, newly generated and retrievably stored DOE transuranic wastes. Section II of this report describes the analytical approach, assumptions, and flow of waste material through sites. Section III presents the waste inventories, disposal and transportation savings, and volume reduction techniques and costs. Section IV contains the results and conclusions of the study. The major conclusions drawn from the study are: For DOE sites with a small amount of waste requiring disposal ( 3 /year) the cost of volume reduction is greater than the transportation and disposal savings from volume reduction provided the waste requires little additional preparation to meet transportation and disposal criteria. Wastes that do not meet these criteria require site specific economic analysis outside the general evaluations of this study. For Idaho National Engineering Laboratory, incineration and metal shredding are cost-effective, provided a facility is to be constructed as a consequence of repackaging the fraction of stored waste which may require repackaging and immobilizing chemical process waste to meet disposal criteria

  8. Mochovce Unit 3 and 4 Completion

    International Nuclear Information System (INIS)

    Aquilanti, G.

    2007-01-01

    Purpose of the Feasibility Study was to define in detail all technical, economic, financial, legal and authorization aspects of Mochovce NPP Unit 3 and 4 completion in order to provide Slovenske Elektrarne, a. s. (SE) and ENEL Top Management with all the necessary information for a final decision on Mochovce Unit 3 and 4. Feasibility study has started in January 2006. SE had the commitment to complete the Feasibility Study within 12 months from Closing of SE acquisition (April 2007). In order not to delay completion of Mochovce Unit 3 and 4, SE has decided to perform, in parallel to the Feasibility study, also all design and permitting activities which are required for the completion of Plant. This has involved anticipation of expenses for approximately 700 MSKK (or approx. 20 MEuro). SE was able to announce the positive decision about completion on Mochovce NPP Unit 3 and 4, two months in advance of the deadline.

  9. Zeroth-order design report for the next linear collider. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Raubenheimer, T.O. [ed.

    1996-05-01

    This Zeroth Order Design Report (ZDR) for the Next Linear Collider (NLC) has been completed as a feasibility study for a TeV-scale linear collider that incorporates a room-temperature accelerator powered by rf microwaves at 11.424 GHz--similar to that presently used in the SLC, but at four times the rf frequency. The purpose of this study is to examine the complete systems of such a collider, to understand how the parts fit together, and to make certain that every required piece has been included. The design presented here is not fully engineered in any sense, but to be assured that the NLC can be built, attention has been given to a number of critical components and issues that present special challenges. More engineering and development of a number of mechanical and electrical systems remain to be done, but the conclusion of this study is that indeed the NLC is technically feasible and can be expected to reach the performance levels required to perform research at the TeV energy scale. Volume one covers the following: the introduction; electron source; positron source; NLC damping rings; bunch compressors and prelinac; low-frequency linacs and compressors; main linacs; design and dynamics; and RF systems for main linacs.

  10. Zeroth-order design report for the next linear collider. Volume 1

    International Nuclear Information System (INIS)

    Raubenheimer, T.O.

    1996-05-01

    This Zeroth Order Design Report (ZDR) for the Next Linear Collider (NLC) has been completed as a feasibility study for a TeV-scale linear collider that incorporates a room-temperature accelerator powered by rf microwaves at 11.424 GHz--similar to that presently used in the SLC, but at four times the rf frequency. The purpose of this study is to examine the complete systems of such a collider, to understand how the parts fit together, and to make certain that every required piece has been included. The design presented here is not fully engineered in any sense, but to be assured that the NLC can be built, attention has been given to a number of critical components and issues that present special challenges. More engineering and development of a number of mechanical and electrical systems remain to be done, but the conclusion of this study is that indeed the NLC is technically feasible and can be expected to reach the performance levels required to perform research at the TeV energy scale. Volume one covers the following: the introduction; electron source; positron source; NLC damping rings; bunch compressors and prelinac; low-frequency linacs and compressors; main linacs; design and dynamics; and RF systems for main linacs

  11. Site Environmental Report for 1999 - Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Ruggieri, M

    2000-08-12

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1. The Site Environmental Report for 1999 is intended to summarize Berkeley Lab's compliance with environmental standards and requirements, characterize environmental management efforts through surveillance and monitoring activities, and highlight significant programs and efforts for calendar year 1999. The report is separated into two volumes. Volume I contains a general overview of the Laboratory, the status of environmental programs, and summary results from surveillance and monitoring activities. Each chapter in Volume I begins with an outline of the sections that follow, including any tables or figures found in the chapter. Readers should use section numbers (e.g., {section}1.5) as navigational tools to find topics of interest in either the printed or the electronic version of the report. Volume II contains the individual data results from monitoring programs.

  12. Double-pass quantum volume hologram

    International Nuclear Information System (INIS)

    Vasilyev, Denis V.; Sokolov, Ivan V.

    2011-01-01

    We propose a scheme for parallel, spatially multimode quantum memory for light. The scheme is based on the propagation in different directions of a quantum signal wave and strong classical reference wave, like in a classical volume hologram and the previously proposed quantum volume hologram [D. V. Vasilyev et al., Phys. Rev. A 81, 020302(R) (2010)]. The medium for the hologram consists of a spatially extended ensemble of cold spin-polarized atoms. In the absence of the collective spin rotation during the interaction, two passes of light for both storage and retrieval are required, and therefore the present scheme can be called a double-pass quantum volume hologram. The scheme is less sensitive to diffraction and therefore is capable of achieving a higher density of storage of spatial modes as compared to the previously proposed thin quantum hologram [D. V. Vasilyev et al., Phys. Rev. A 77, 020302(R) (2008)], which also requires two passes of light for both storage and retrieval. However, the present scheme allows one to achieve a good memory performance with a lower optical depth of the atomic sample as compared to the quantum volume hologram. A quantum hologram capable of storing entangled images can become an important ingredient in quantum information processing and quantum imaging.

  13. CONTAMINATED SOIL VOLUME ESTIMATE TRACKING METHODOLOGY

    International Nuclear Information System (INIS)

    Durham, L.A.; Johnson, R.L.; Rieman, C.; Kenna, T.; Pilon, R.

    2003-01-01

    The U.S. Army Corps of Engineers (USACE) is conducting a cleanup of radiologically contaminated properties under the Formerly Utilized Sites Remedial Action Program (FUSRAP). The largest cost element for most of the FUSRAP sites is the transportation and disposal of contaminated soil. Project managers and engineers need an estimate of the volume of contaminated soil to determine project costs and schedule. Once excavation activities begin and additional remedial action data are collected, the actual quantity of contaminated soil often deviates from the original estimate, resulting in cost and schedule impacts to the project. The project costs and schedule need to be frequently updated by tracking the actual quantities of excavated soil and contaminated soil remaining during the life of a remedial action project. A soil volume estimate tracking methodology was developed to provide a mechanism for project managers and engineers to create better project controls of costs and schedule. For the FUSRAP Linde site, an estimate of the initial volume of in situ soil above the specified cleanup guidelines was calculated on the basis of discrete soil sample data and other relevant data using indicator geostatistical techniques combined with Bayesian analysis. During the remedial action, updated volume estimates of remaining in situ soils requiring excavation were calculated on a periodic basis. In addition to taking into account the volume of soil that had been excavated, the updated volume estimates incorporated both new gamma walkover surveys and discrete sample data collected as part of the remedial action. A civil survey company provided periodic estimates of actual in situ excavated soil volumes. By using the results from the civil survey of actual in situ volumes excavated and the updated estimate of the remaining volume of contaminated soil requiring excavation, the USACE Buffalo District was able to forecast and update project costs and schedule. The soil volume

  14. Human gallbladder pressure and volume

    DEFF Research Database (Denmark)

    Borly, L; Højgaard, L; Grønvall, S

    1996-01-01

    volume with only slight changes in intraluminal pressure (n = 4). Except for the zero drift, this piece of equipment seemed to fulfil the requirements of being able to measure pressure in the GB. In vivo measurements showed a good clinical reproducibility of the method, and also that respiration...... influenced by respiration (n = 8) and the pressure seems to be higher in the sitting position than in the supine position (n = 5). Cystic duct opening pressure was 10.4, 11.2 and 16.8 mmHg (n = 3). Pressure-volume responses showed that the GB up to a certain volume could accommodate increases in intraluminal...... and patient posture influenced the pressure measurements. Further, a GB pressure-volume relationship was demonstrated, and the possibility of a cystic duct opening pressure was described....

  15. New complete sample of identified radio sources. Part 2. Statistical study

    International Nuclear Information System (INIS)

    Soltan, A.

    1978-01-01

    Complete sample of radio sources with known redshifts selected in Paper I is studied. Source counts in the sample and the luminosity - volume test show that both quasars and galaxies are subject to the evolution. Luminosity functions for different ranges of redshifts are obtained. Due to many uncertainties only simplified models of the evolution are tested. Exponential decline of the liminosity with time of all the bright sources is in a good agreement both with the luminosity- volume test and N(S) realtion in the entire range of observed flux densities. It is shown that sources in the sample are randomly distributed in scales greater than about 17 Mpc. (author)

  16. Aperiodic Volume Optics

    Science.gov (United States)

    Gerke, Tim D.

    Presented in this thesis is an investigation into aperiodic volume optical devices. The three main topics of research and discussion are the aperiodic volume optical devices that we call computer-generated volume holograms (CGVH), defects within periodic 3D photonic crystals, and non-periodic, but ordered 3D quasicrystals. The first of these devices, CGVHs, are designed and investigated numerically and experimentally. We study the performance of multi-layered amplitude computer-generated volume holograms in terms of efficiency and angular/frequency selectivity. Simulation results show that such aperiodic devices can increase diffraction efficiency relative to periodic amplitude volume holograms while maintaining angular and wavelength selectivity. CGVHs are also designed as voxelated volumes using a new projection optimization algorithm. They are investigated using a volumetric diffraction simulation and a standard 3D beam propagation technique as well as experimentally. Both simulation and experiment verify that the structures function according to their design. These represent the first diffractive structures that have the capacity for generating arbitrary transmission and reflection wave fronts and that provide the ability for multiplexing arbitrary functionality given different illumination conditions. Also investigated and discussed in this thesis are 3D photonic crystals and quasicrystals. We demonstrate that these devices can be fabricated using a femtosecond laser direct writing system that is particularly appropriate for fabrication of such arbitrary 3D structures. We also show that these devices can provide 3D partial bandgaps which could become complete bandgaps if fabricated using high index materials or by coating lower index materials with high index metals. Our fabrication method is particularly suited to the fabrication of engineered defects within the periodic or quasi-periodic systems. We demonstrate the potential for fabricating defects within

  17. Complete rerouting protection

    DEFF Research Database (Denmark)

    Stidsen, Thomas K.; Kjærulff, Peter

    2006-01-01

    Protection of communication against network failures is becoming increasingly important and in this paper we present the most capacity efficient protection method possible, the complete rerouting protection method, when requiring that all communication should be restored in case of a single link...... network failure. We present a linear programming model of the protection method and a column generation algorithm. For 6 real world networks, the minimal restoration overbuild network capacity is between 13% and 78%. We further study the importance of the density of the network, derive analytical bounds...

  18. Can Emergency Physicians Perform Common Carotid Doppler Flow Measurements to Assess Volume Responsiveness?

    Directory of Open Access Journals (Sweden)

    Stolz, Lori A.

    2015-02-01

    Full Text Available Introduction: Common carotid flow measurements may be clinically useful to determine volume responsiveness. The objective of this study was to assess the ability of emergency physicians (EP to obtain sonographic images and measurements of the common carotid artery velocity time integral (VTi for potential use in assessing volume responsiveness in the clinical setting. Methods: In this prospective observational study, we showed a five-minute instructional video demonstrating a technique to obtain common carotid ultrasound images and measure the common carotid VTi to emergency medicine (EM residents. Participants were then asked to image the common carotid artery and obtain VTi measurements. Expert sonographers observed participants imaging in real time and recorded their performance on nine performance measures. An expert sonographer graded image quality. Participants were timed and answered questions regarding ease of examination and their confidence in obtaining the images. Results: A total of 30 EM residents participated in this study and each performed the examination twice. Average time required to complete one examination was 2.9 minutes (95% CI [2.4-3.4 min]. Participants successfully completed all performance measures greater than 75% of the time, with the exception of obtaining measurements during systole, which was completed in 65% of examinations. Median resident overall confidence in accurately performing carotid VTi measurements was 3 (on a scale of 1 [not confident] to 5 [confident]. Conclusion: EM residents at our institution learned the technique for obtaining common carotid artery Doppler flow measurements after viewing a brief instructional video. When assessed at performing this examination, they completed several performance measures with greater than 75% success. No differences were found between novice and experienced groups. [West J Emerg Med. 2015;16(2:255–259.

  19. Guidance and Control Software Project Data - Volume 2: Development Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the development documents from the GCS project. Volume 2 contains three appendices: A. Guidance and Control Software Development Specification; B. Design Description for the Pluto Implementation of the Guidance and Control Software; and C. Source Code for the Pluto Implementation of the Guidance and Control Software

  20. The Returns to Completion or Partial Completion of a Qualification in the Trades. Research Report

    Science.gov (United States)

    Lu, Tham

    2015-01-01

    Many students do not complete full qualifications in the vocational education and training (VET) system because their intention is to obtain only the particular skills they require. This can be achieved through the acquisition of skill sets; these enable flexibility in training to quickly respond to changes in the labour market. Skill sets may…

  1. Transportable aerosol sampling station with fixed volume (15 l) DMPA-15

    International Nuclear Information System (INIS)

    Giolu, G.; Guta, V.

    1999-01-01

    The mobile installation is used for air-sampling operations with fixed intake volumes, to be analysed by laboratories of routine environmental air monitoring. The station consists of several units, installed on a two-wheel mobile carriage-type platform: - a double - diaphragm pump (ensuring oil separation) that provides air intake and its evacuation to the air-analysers. The sampling and control unit has the following functions: - intake ensured by the pump that aspirates fixed volumes of air from the ambient atmosphere and feeding with it an inflatable rubber chamber. Air intake is automatically stopped as the cushion is filled up completely. A separation clamp is provided to seal up the cushion; - exhaust - allows the residual air to be evacuated from the cushion, ensuring its 'self-cleaning'; - shut down, manually operated; - analyse, the aerosol containing sample is aspirated from the inflatable rubber chamber and evacuated through a flow regulator to the analyser; - stop, canceling any previous commands. A relay unit controls the pneumatic lines and a pressure relay provides automatic stop of air intake process. The following technical features are given: - The fixed air volume in the chamber, 15 l - the air flow at the exit from the flow-meter, 0 - 15 l/min; - power requirements, 220 V/ 50 Hz; - power consumption, max. 1,5 kW; - overall dimensions, 460 x 500 x 820 mm; - weight, 53 kg. (authors)

  2. Mobile-robot navigation with complete coverage of unstructured environments

    OpenAIRE

    García Armada, Elena; González de Santos, Pablo

    2004-01-01

    There are some mobile-robot applications that require the complete coverage of an unstructured environment. Examples are humanitarian de-mining and floor-cleaning tasks. A complete-coverage algorithm is then used, a path-planning technique that allows the robot to pass over all points in the environment, avoiding unknown obstacles. Different coverage algorithms exist, but they fail working in unstructured environments. This paper details a complete-coverage algorithm for unstructured environm...

  3. Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis.

    Science.gov (United States)

    Kim, Gloria; Chu, Renxin; Yousuf, Fawad; Tauhid, Shahamat; Stazzone, Lynn; Houtchens, Maria K; Stankiewicz, James M; Severson, Christopher; Kimbrough, Dorlan; Quintana, Francisco J; Chitnis, Tanuja; Weiner, Howard L; Healy, Brian C; Bakshi, Rohit

    2017-11-01

    The subcortical deep gray matter (DGM) develops selective, progressive, and clinically relevant atrophy in progressive forms of multiple sclerosis (PMS). This patient population is the target of active neurotherapeutic development, requiring the availability of outcome measures. We tested a fully automated MRI analysis pipeline to assess DGM atrophy in PMS. Consistent 3D T1-weighted high-resolution 3T brain MRI was obtained over one year in 19 consecutive patients with PMS [15 secondary progressive, 4 primary progressive, 53% women, age (mean±SD) 50.8±8.0 years, Expanded Disability Status Scale (median, range) 5.0, 2.0-6.5)]. DGM segmentation applied the fully automated FSL-FIRST pipeline ( http://fsl.fmrib.ox.ac.uk ). Total DGM volume was the sum of the caudate, putamen, globus pallidus, and thalamus. On-study change was calculated using a random-effects linear regression model. We detected one-year decreases in raw [mean (95% confidence interval): -0.749 ml (-1.455, -0.043), p = 0.039] and annualized [-0.754 ml/year (-1.492, -0.016), p = 0.046] total DGM volumes. A treatment trial for an intervention that would show a 50% reduction in DGM brain atrophy would require a sample size of 123 patients for a single-arm study (one-year run-in followed by one-year on-treatment). For a two-arm placebo-controlled one-year study, 242 patients would be required per arm. The use of DGM fraction required more patients. The thalamus, putamen, and globus pallidus, showed smaller effect sizes in their on-study changes than the total DGM; however, for the caudate, the effect sizes were somewhat larger. DGM atrophy may prove efficient as a short-term outcome for proof-of-concept neurotherapeutic trials in PMS.

  4. Reactor plant for Belene NPP completion

    International Nuclear Information System (INIS)

    Dragunov, Yu. G.; Ryzhov, S. B.; Ermakov, D. N.; Repin, A. I.

    2004-01-01

    Construction of 'Belene' NPP was started at the end of 80-ties using project U-87 with V-320 reactor plant, general designer of this plant is OKB 'Gidropress'. At the beginning of 90-ties, on completing the considerable number of deliveries and performance of civil engineering work at the site the NPP construction was suspended. Nowadays, considering the state of affairs at the site and the work performed by Bulgarian Party on preservation of the equipment delivered, the most perspective is supposed to be implementation of the following versions in completing 'Belene' NPP: for completion of Unit 1 - reactor plant VVER-1000 on the basis of V-320 reactor with the maximum use of the delivered equipment (V-320M) having the extended service life and safety improvement; for Unit 2 - advanced reactor plant VVER-1000. For the upgraded reactor plant V-230M the basic solutions and characteristics are presented, as well as the calculated justification of strength and safety analyses, design of the reactor core and fuel cycle, instrumentation and control systems, application of the 'leak-before break' in the project and implementation of safety measures. For the modernised reactor plant V-392M the main characteristics and basic changes are presented, concerning reactor pressure vessel, steam generator, reactor coolant pump set. Design of NPP with the modernized reactor plant V-320M meets the up-to-date requirements and can be licensed for completion and operation. In the design of NPP with the advanced reactor plant the basic solutions and the equipment are used that are similar to those used in standard reactor plant V-320 and new one with VVER-1000 under construction and completion in Russia, and abroad. Compliance of reactor design with the up-to-date international requirements, considering the extended service life of the main equipment, shows its rather high potential for implementation during completion of 'Belene' NPP

  5. Traffic speed data imputation method based on tensor completion.

    Science.gov (United States)

    Ran, Bin; Tan, Huachun; Feng, Jianshuai; Liu, Ying; Wang, Wuhong

    2015-01-01

    Traffic speed data plays a key role in Intelligent Transportation Systems (ITS); however, missing traffic data would affect the performance of ITS as well as Advanced Traveler Information Systems (ATIS). In this paper, we handle this issue by a novel tensor-based imputation approach. Specifically, tensor pattern is adopted for modeling traffic speed data and then High accurate Low Rank Tensor Completion (HaLRTC), an efficient tensor completion method, is employed to estimate the missing traffic speed data. This proposed method is able to recover missing entries from given entries, which may be noisy, considering severe fluctuation of traffic speed data compared with traffic volume. The proposed method is evaluated on Performance Measurement System (PeMS) database, and the experimental results show the superiority of the proposed approach over state-of-the-art baseline approaches.

  6. Experimental estimation of the heat energy dissipated in a volume surrounding the tip of a fatigue crack

    Directory of Open Access Journals (Sweden)

    G. Meneghetti

    2016-01-01

    Full Text Available Fatigue crack initiation and propagation involve plastic strains that require some work to be done on the material. Most of this irreversible energy is dissipated as heat and consequently the material temperature increases. The heat being an indicator of the intense plastic strains occurring at the tip of a propagating fatigue crack, when combined with the Neuber’s structural volume concept, it might be used as an experimentally measurable parameter to assess the fatigue damage accumulation rate of cracked components. On the basis of a theoretical model published previously, in this work the heat energy dissipated in a volume surrounding the crack tip is estimated experimentally on the basis of the radial temperature profiles measured by means of an infrared camera. The definition of the structural volume in a fatigue sense is beyond the scope of the present paper. The experimental crack propagation tests were carried out on hot-rolled, 6-mm-thick AISI 304L stainless steel specimens subject to completely reversed axial fatigue loading.

  7. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 22. Nuclear considerations for repository design

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Y/OWI/TM-36/22, ''Nuclear Considerations for Repository Design,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. Included in this volume are baseline design considerations such as characteristics of canisters, drums, casks, overpacks, and shipping containers; maximum allowable and actual decay-heat levels; and canister radiation levels. Other topics include safeguard and protection considerations; occupational radiation exposure including ALARA programs; shielding of canisters, transporters and forklift trucks; monitoring considerations; mine water treatment; canister integrity; and criticality calculations

  8. Unconventional Oil and Gas Spills: Risks, Mitigation Priorities, and State Reporting Requirements.

    Science.gov (United States)

    Patterson, Lauren A; Konschnik, Katherine E; Wiseman, Hannah; Fargione, Joseph; Maloney, Kelly O; Kiesecker, Joseph; Nicot, Jean-Philippe; Baruch-Mordo, Sharon; Entrekin, Sally; Trainor, Anne; Saiers, James E

    2017-03-07

    Rapid growth in unconventional oil and gas (UOG) has produced jobs, revenue, and energy, but also concerns over spills and environmental risks. We assessed spill data from 2005 to 2014 at 31 481 UOG wells in Colorado, New Mexico, North Dakota, and Pennsylvania. We found 2-16% of wells reported a spill each year. Median spill volumes ranged from 0.5 m 3 in Pennsylvania to 4.9 m 3 in New Mexico; the largest spills exceeded 100 m 3 . Seventy-five to 94% of spills occurred within the first three years of well life when wells were drilled, completed, and had their largest production volumes. Across all four states, 50% of spills were related to storage and moving fluids via flowlines. Reporting rates varied by state, affecting spill rates and requiring extensive time and effort getting data into a usable format. Enhanced and standardized regulatory requirements for reporting spills could improve the accuracy and speed of analyses to identify and prevent spill risks and mitigate potential environmental damage. Transparency for data sharing and analysis will be increasingly important as UOG development expands. We designed an interactive spills data visualization tool ( http://snappartnership.net/groups/hydraulic-fracturing/webapp/spills.html ) to illustrate the value of having standardized, public data.

  9. Improving horizontal completions on heterogeneous tight shales

    Energy Technology Data Exchange (ETDEWEB)

    Suarez-Rivera, Roberto; Deenadayalu, Chaitanya; Chertov, Maxim; Novalo Hartanto, Ricardo; Gathogo, Patrick [Schlumberger (United States); Kunjir, Rahul [University of Utah (United States)

    2011-07-01

    Evaluation of the two formation characteristics conducive to economic well production is important when tight shale formation characterization and completion design are being considered. This paper presents the basic understanding required to improve the efficiency of horizontal completions in oil and gas producing shales. Guidelines are defined for effective perforation and fracturing to improve the efficiency and sustainability of horizontal completions using extensive laboratory characterization of mechanical properties on core, core/log integration and continuous mapping of these properties by logging-while-drilling (LWD) methods. The objective is to improve completion design efficiency. This is accomplished by suitable selection of perforation intervals based on an understanding of the relevant physical processes and rock characterization. Conditions at two reservoir regions, the near-wellbore and the far-wellbore, are outlined and are essential to completion design. From the study, it can be concluded that tight shales are strongly anisotropic and cannot be approximated using isotropic models.

  10. MRI and Diffusion-weighted MRI Volumetry for Identification of Complete Tumor Responders After Preoperative Chemoradiotherapy in Patients With Rectal Cancer: A Bi-institutional Validation Study.

    Science.gov (United States)

    Lambregts, Doenja M J; Rao, Sheng-Xiang; Sassen, Sander; Martens, Milou H; Heijnen, Luc A; Buijsen, Jeroen; Sosef, Meindert; Beets, Geerard L; Vliegen, Roy A; Beets-Tan, Regina G H

    2015-12-01

    Retrospective single-center studies have shown that diffusion-weighted magnetic resonance imaging (DWI) is promising for identification of patients with rectal cancer with a complete tumor response after neoadjuvant chemoradiotherapy (CRT), using certain volumetric thresholds. This study aims to validate the diagnostic value of these volume thresholds in a larger, independent, and bi-institutional patient cohort. A total of 112 patients with locally advanced rectal cancer (2 centers) treated with a long course of CRT were enrolled. Patients underwent standard T2W-magnetic resonance imaging and DWI, both pre- and post-CRT. Two experienced readers independently determined pre-CRT and post-CRT tumor volumes (cm) on T2W-magnetic resonance image and diffusion-weighted magnetic resonance image by means of freehand tumor delineation. Tumor volume reduction rates (Δvolume) were calculated. Previously determined T2W and DWI threshold values for prevolume, postvolume, and Δvolume were tested to "prospectively" assess their respective diagnostic value in discriminating patients with a complete tumor response from patients with residual tumor. Twenty patients had a complete response. Using the average measurements between the 2 readers, areas under the curve for the pre-/post-/Δvolumes was 0.73/0.82/0.78 for T2W-magnetic resonance imaging and 0.77/0.92/0.86 for DWI, respectively. For T2W-volumetry, sensitivity and specificity using the predefined volume thresholds were 55% and 74% for pre-, 60% and 89% for post-, and 60% and 86% for Δvolume. For DWI volumetry, sensitivity and specificity were 65% and 76% for pre-, 70% and 98% for post-, and 70% and 93% for Δvolume. Previously established DWI volume thresholds can be reproduced with good results. Post-CRT DWI volumetry offers the best results for the detection of patients with a complete response after CRT with an area under the curve of 0.92, sensitivity of 70%, and specificity of 98%.

  11. EUS-guided recanalization of complete gastrointestinal strictures

    Directory of Open Access Journals (Sweden)

    Miguel Martínez-Guillén

    Full Text Available Background and aim: Complete gastrointestinal strictures are a technically demanding problem. In this setting, an anterograde technique is associated with a high risk of complications and a combined anterograde-retrograde technique requires a prior ostomy. Our aim was to assess the outcome of a first case series for the management of complete gastrointestinal strictures using endoscopic ultrasound (EUS-guided puncture as a novel endoscopic approach. Patients and methods: This retrospective case-series describes four cases that were referred for treatment of complete benign gastrointestinal strictures, three upper and one lower. Recanalization was attempted with EUS-guided puncture using a 22G or 19G needle and contrast filling was visualized by fluoroscopy. Afterwards, a cystotome and/or a dilator balloon were used under endoscopic and fluoroscopic guidance. A fully covered metal stent was placed in two cases, keeping the strictures open in order to prevent another stricture. Feasibility, adverse events, efficacy and the number of dilations required after recanalization were evaluated. Results: Technical and clinical success was achieved in three of the four cases (75%. A first dilation was performed using a dilator balloon in all successful cases and fully covered metal stents were used in two cases. These patients underwent a consecutive number of balloon dilatations (range 1-4 and all three were able to eat a soft diet. No adverse events were related to the EUS-guided approach. In the failed case with a long stricture (> 3 cm, an endoscopic rendezvous technique was attempted which caused a pneumothorax requiring a chest tube placement. Conclusion: EUS-guided recanalization, as a first approach in the treatment of complete digestive stricture, is a feasible and promising procedure that can help to avoid major surgery.

  12. High-Frequency Jet Ventilation for Complete Target Immobilization and Reduction of Planning Target Volume in Stereotactic High Single-Dose Irradiation of Stage I Non-Small Cell Lung Cancer and Lung Metastases

    International Nuclear Information System (INIS)

    Fritz, Peter; Kraus, Hans-Joerg; Muehlnickel, Werner; Sassmann, Volker; Hering, Werner; Strauch, Konstantin

    2010-01-01

    Purpose: To demonstrate the feasibility of complete target immobilization by means of high-frequency jet ventilation (HFJV); and to show that the saving of planning target volume (PTV) on the stereotactic body radiation therapy (SBRT) under HFJV, compared with SBRT with respiratory motion, can be predicted with reliable accuracy by computed tomography (CT) scans at peak inspiration phase. Methods and Materials: A comparison regarding different methods for defining the PTV was carried out in 22 patients with tumors that clearly moved with respiration. A movement span of the gross tumor volume (GTV) was defined by fusing respiration-correlated CT scans. The PTV enclosed the GTV positions with a safety margin throughout the breathing cycle. To create a PTV from CT scans acquired under HFJV, the same margins were drawn around the immobilized target. In addition, peak inspiration phase CT images (PIP-CTs) were used to approximate a target immobilized by HFJV. Results: The resulting HFJV-PTVs were between 11.6% and 45.4% smaller than the baseline values calculated as respiration-correlated CT-PTVs (median volume reduction, 25.4%). Tentative planning by means of PIP-CT PTVs predicted that in 19 of 22 patients, use of HFJV would lead to a reduction in volume of ≥20%. Using this threshold yielded a positive predictive value of 0.89, as well as a sensitivity of 0.94 and a specificity of 0.5. Conclusions: In all patients, SBRT under HFJV provided a reliable immobilization of the GTVs and achieved a reduction in PTVs, regardless of patient compliance. Tentative planning facilitated the selection of patients who could better undergo radiation in respiratory standstill, both with greater accuracy and lung protection.

  13. Volume reduction equipment for low-level radwastes

    International Nuclear Information System (INIS)

    Hofmann, J.; Schlich, E.

    1982-01-01

    Volume reduction of low-level radwaste has been used for years in Germany to reduce the on-site storage capacity which is required until an ultimate disposal site is available. The incineration of trash is a well established cost effective method for dry active waste volume reduction and now liquid radwaste treatment is gaining the operational experience which establishes it as a routine procedure. Resin pyrolysis is a promising new development which when successfully implemented will augment the other systems by safely volume reducing a radwaste which is of increasing concern

  14. Three-body unitarity in the finite volume

    Energy Technology Data Exchange (ETDEWEB)

    Mai, M. [The George Washington University, Washington, DC (United States); Doering, M. [The George Washington University, Washington, DC (United States); Thomas Jefferson National Accelerator Facility, Newport News, VA (United States)

    2017-12-15

    The physical interpretation of lattice QCD simulations, performed in a small volume, requires an extrapolation to the infinite volume. A method is proposed to perform such an extrapolation for three interacting particles at energies above threshold. For this, a recently formulated relativistic 3 → 3 amplitude based on the isobar formulation is adapted to the finite volume. The guiding principle is two- and three-body unitarity that imposes the imaginary parts of the amplitude in the infinite volume. In turn, these imaginary parts dictate the leading power-law finite-volume effects. It is demonstrated that finite-volume poles arising from the singular interaction, from the external two-body sub-amplitudes, and from the disconnected topology cancel exactly leaving only the genuine three-body eigenvalues. The corresponding quantization condition is derived for the case of three identical scalar-isoscalar particles and its numerical implementation is demonstrated. (orig.)

  15. European Utility Requirements: leveling the European electricity producers' playing ground for new NPPs

    International Nuclear Information System (INIS)

    Bernard Roche

    2006-01-01

    Full text of publication follows: Since 1992, the European Utility Requirement (EUR) document has been developed by the major European electricity producers. The main driver to this work has been the construction of a unified European market. The electricity producers have set out design requirements adapted to this new European environment, while keeping in mind experience feedback from operating NPPs worldwide. The EUR document is now fully operational and its set of generic requirements have been recently used as bid specification in Finland and in China. The EUR document keeps developing in two directions: 1- completing the assessment of the projects that could be proposed by the vendors for the European market. Five projects have been assessed between 1999 and 2002: BWR90, EPR, EP1000, ABWR and SWR1000. Two new projects are being assessed, the Westinghouse AP1000 and the Russian VVER AES92. It is currently planned to publish these two new assessments in the first half of 2006. Others may be undertaken meanwhile. 2- revision of the generic requirements. A revision C of the volume 4 dedicated to power generation plant is being completed. It includes responses to vendors comments and feedback from the TVO call for bid for Finland 5. A revision D of the volumes 1 and 2 dedicated to nuclear islands is foreseen. The main contributions to this revision are the harmonization actions going on in Europe about nuclear safety (WENRA study on reactor safety harmonization, EC works, evolution of the IAEA guides and requirements), the harmonization works on the conditions of connection to the European HV grid as well as harmonization works on other matters, like codes and standards. This has given a unified frame in which the future nuclear plants can be designed and built. In this frame development of standards designs usable throughout Europe without major design change is possible, thus helping to increase competition, and ultimately to save investment and operating costs

  16. Determinants of successful completion of pulmonary rehabilitation in COPD

    Directory of Open Access Journals (Sweden)

    Brown AT

    2016-02-01

    Full Text Available Angel T Brown,1 Jason Hitchcock,2 Christopher Schumann,2 J Michael Wells,1,3,4 Mark T Dransfield,1,3,4 Surya P Bhatt1,3 1Division of Pulmonary, Allergy, and Critical Care Medicine, 2Department of Cardiopulmonary Rehabilitation, 3UAB Lung Health Center, University of Alabama at Birmingham, 4Veterans Affairs Medical Center, Birmingham, AL, USA Background: Despite known benefits, a significant proportion of patients with COPD do not complete pulmonary rehabilitation (PR. Little is known regarding which factors promote successful completion of PR. Methods: We analyzed data from a prospectively maintained database of subjects with COPD who attended a PR program at the University of Alabama at Birmingham, from 1996 to 2013. Subjects were categorized as either completers or non-completers, based on successful completion of at least 8 weeks of PR. Demographics and comorbidities were recorded. Short Form 36 Health Survey, Beck Depression Inventory-II, and San Diego Shortness of Breath Questionnaire were administered to all participants at baseline and on completion of PR to assess participants’ perception of their health status, severity of depression, and dyspnea with performance of activities of daily living. Univariate and multivariable analyses were performed to identify predictors of successful completion of PR. Results: Four hundred and forty subjects were included, of whom 229 completed PR. Forty-one percent were female, and 17% were African American. Compared with non-completers, completers had greater Short Form 36 Health Survey pain score, lower forced expiratory volume in the first second, and lower Beck Depression Inventory score, and included a lower percentage of current smokers. On multivariate analysis, cigarette smoking at enrollment was associated with lower likelihood of completion of PR (adjusted odds ratio 0.38, 95% confidence interval 0.16–0.90; P=0.02.Conclusion: Cigarette smoking was the sole independent predictor of PR

  17. High integrity software for nuclear power plants: Candidate guidelines, technical basis and research needs. Main report, Volume 2

    International Nuclear Information System (INIS)

    Seth, S.; Bail, W.; Cleaves, D.; Cohen, H.; Hybertson, D.; Schaefer, C.; Stark, G.; Ta, A.; Ulery, B.

    1995-06-01

    The work documented in this report was performed in support of the US Nuclear Regulatory Commission to examine the technical basis for candidate guidelines that could be considered in reviewing and evaluating high integrity computer e following software development and assurance activities: Requirements specification; design; coding; verification and validation, inclukding static analysis and dynamic testing; safety analysis; operation and maintenance; configuration management; quality assurance; and planning and management. Each activity (framework element) was subdivided into technical areas (framework subelements). The report describes the development of approximately 200 candidate guidelines that span the entire ran e identification, categorization and prioritization of technical basis for those candidate guidelines; and the identification, categorization and prioritization of research needs for improving the technical basis. The report has two volumes: Volume 1, Executive Summary includes an overview of the framwork and of each framework element, the complete set of candidate guidelines, the results of the assessment of the technical basis for each candidate guideline, and a discussion of research needs that support the regulatory function; this document, Volume 2, is the main report

  18. High integrity software for nuclear power plants: Candidate guidelines, technical basis and research needs. Main report, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Seth, S.; Bail, W.; Cleaves, D.; Cohen, H.; Hybertson, D.; Schaefer, C.; Stark, G.; Ta, A.; Ulery, B. [Mitre Corp., McLean, VA (United States)

    1995-06-01

    The work documented in this report was performed in support of the US Nuclear Regulatory Commission to examine the technical basis for candidate guidelines that could be considered in reviewing and evaluating high integrity computer e following software development and assurance activities: Requirements specification; design; coding; verification and validation, inclukding static analysis and dynamic testing; safety analysis; operation and maintenance; configuration management; quality assurance; and planning and management. Each activity (framework element) was subdivided into technical areas (framework subelements). The report describes the development of approximately 200 candidate guidelines that span the entire ran e identification, categorization and prioritization of technical basis for those candidate guidelines; and the identification, categorization and prioritization of research needs for improving the technical basis. The report has two volumes: Volume 1, Executive Summary includes an overview of the framwork and of each framework element, the complete set of candidate guidelines, the results of the assessment of the technical basis for each candidate guideline, and a discussion of research needs that support the regulatory function; this document, Volume 2, is the main report.

  19. Inductively coupled plasma emission spectroscopy. Part II: applications and fundamentals. Volume 2

    International Nuclear Information System (INIS)

    Boumans, P.W.J.M.

    1987-01-01

    This is the second part of the two-volume treatise by this well-known and respected author. This volume reviews applications of inductively coupled plasma atomic emission spectroscopy (ICP-AES), summarizes fundamental studies, and compares ICP-AES methods with other methods of analysis. The first six chapters are devoted to specific fields of application, including the following: metals and other industrial materials, geology, the environment, agriculture and food, biology and clinical analysis, and organic materials. The chapter on the analysis of organic materials also covers the special instrumental considerations required when organic solvents are introduced into an inductively coupled plasma. A chapter on the direct analysis of solids completes the first part of this volume. Each of the applications chapters begins with a summary of the types of samples that are encountered in that field, and the kinds of problems that an elemental analysis can help to solve. This is followed by a tutorial approach covering applicability, advantages, and limitations of the methods. The coverage is thorough, including sample handling, storage, and preparation, acid, and fusion dissolution, avoiding contamination, methods of preconcentration, the types of interferences that can be expected and ways to reduce them, and the types of ICP plasmas that are used. The second half of the volume covers fundamental studies of ICP-AES: basic processes of aerosol generation, plasma modeling and computer simulation, spectroscopic diagnostics, excitation mechanisms, and discharge characteristics. This section introduces the experimental and modeling methods that have been used to obtain fundamental information about ICPs

  20. Traffic Speed Data Imputation Method Based on Tensor Completion

    Directory of Open Access Journals (Sweden)

    Bin Ran

    2015-01-01

    Full Text Available Traffic speed data plays a key role in Intelligent Transportation Systems (ITS; however, missing traffic data would affect the performance of ITS as well as Advanced Traveler Information Systems (ATIS. In this paper, we handle this issue by a novel tensor-based imputation approach. Specifically, tensor pattern is adopted for modeling traffic speed data and then High accurate Low Rank Tensor Completion (HaLRTC, an efficient tensor completion method, is employed to estimate the missing traffic speed data. This proposed method is able to recover missing entries from given entries, which may be noisy, considering severe fluctuation of traffic speed data compared with traffic volume. The proposed method is evaluated on Performance Measurement System (PeMS database, and the experimental results show the superiority of the proposed approach over state-of-the-art baseline approaches.

  1. Optimizing Completion Time and Energy Consumption in a Bidirectional Relay Network

    DEFF Research Database (Denmark)

    Liu, Huaping; Sun, Fan; Thai, Chan

    2012-01-01

    consumption required for multiple flows depends on the current channel realizations, transmission methods used and, notably, the relation between the data sizes of different source nodes. In this paper we investigate the shortest completion time and minimal energy consumption in a two-way relay wireless...... arises for the minimal required energy. While the requirement for minimal energy consumption is obvious, the shortest completion time is relevant when certain multi-node network needs to reserve the wireless medium in order to carry out the data exchange among its nodes. The completion time/energy...... network. The system applies optimal time multiplexing of several known transmission methods, including one-way relaying and wireless network coding (WNC). We show that when the relay applies Amplify-and-Forward (AF), both minimizations are linear optimization problems. On the other hand, when the relay...

  2. Fusion Engineering Device. Volume IV. Physics basis and physics R and D requirements

    International Nuclear Information System (INIS)

    1981-10-01

    This volume covers the following issues: (1) confinement scaling, (2) cross section shaping, limits on B and q, (3) ion cyclotron heating, (4) neutral beam heating, (5) mechanical pump limiter, (6) poloidal divertor, and (7) non-divertor active impurity control

  3. Methodology to Forecast Volume and Cost of Cancer Drugs in Low- and Middle-Income Countries

    Directory of Open Access Journals (Sweden)

    Yehoda M. Martei

    2018-02-01

    Full Text Available Purpose: In low- and middle-income countries (LMICs, frequent outages of the stock of cancer drugs undermine cancer care delivery and are potentially fatal for patients with cancer. The aim of this study is to describe a methodologic approach to forecast chemotherapy volume and estimate cost that can be readily updated and applied in most LMICs. Methods: Prerequisite data for forecasting are population-based incidence data and cost estimates per unit of drug to be ordered. We used the supplementary guidelines from the WHO list of essential medicines for cancer to predict treatment plans and ordering patterns. We used de-identified aggregate data from the Botswana National Cancer Registry to estimate incident cases. The WHO Management Sciences for Health International Price Indicator was used to estimate unit costs per drug. Results: Chemotherapy volume required for incident cancer cases was estimated as the product of the standardized dose required to complete a full treatment regimen per patient, with a given cancer diagnosis and stage, multiplied by the total number of incident cancer cases with the respective diagnosis. The estimated chemotherapy costs to treat the 10 most common cancers in the public health care sector of Botswana is approximately 2.3 million US dollars. An estimated 66% of the budget is allocated to costs of rituximab and trastuzumab alone, which are used by approximately 10% of the cancer population. Conclusion: This method provides a reproducible approach to forecast chemotherapy volume and cost in LMICs. The chemotherapy volume and cost outputs of this methodology provide key stakeholders with valuable information that can guide budget estimation, resource allocation, and drug-price negotiations for cancer treatment. Ultimately, this will minimize drug shortages or outages and reduce potential loss of lives that result from an erratic drug supply.

  4. Endobronchial valves in severe emphysematous patients: CT evaluation of lung fissures completeness, treatment radiological response and quantitative emphysema analysis

    Energy Technology Data Exchange (ETDEWEB)

    Koenigkam-Santos, Marcel, E-mail: marcelk46@yahoo.com.br, E-mail: marcelk46@usp.b [Universidade de Sao Paulo (HCFMRP/USP), Ribeirao Preto, SP (Brazil). Hospital das Clinicas da Faculdade de Medicina; Paula, Wagner Diniz de [University of Brasilia (UnB), DF (Brazil). Brasilia University Hospital; Gompelmann, Daniela [University of Heidelberg (Germany). Department of Pneumology and Respiratory Medicine of the Chest Clinic (Thoraxklinik); Kauczor, Hans-Ulrich [University of Heidelberg (Germany). Department of Diagnostic and Interventional Radiology; Heussel, Claus Peter; Puderbach, Michael [University of Heidelberg (Germany). Department of Diagnostic and Interventional Radiology with Nuclear Medicine of the Chest Clinic (Thoraxklinik)

    2013-01-15

    Objective: To evaluate lung fissures completeness, post-treatment radiological response and quantitative CT analysis (QCTA) in a population of severe emphysematous patients submitted to endobronchial valves (EBV) implantation. Materials and Methods: Multi-detectors CT exams of 29 patients were studied, using thin-section low dose protocol without contrast. Two radiologists retrospectively reviewed all images in consensus; fissures completeness was estimated in 5% increments and post-EBV radiological response (target lobe atelectasis/volume loss) was evaluated. QCTA was performed in pre and post-treatment scans using a fully automated software. Results: CT response was present in 16/29 patients. In the negative CT response group, all 13 patients presented incomplete fissures, and mean oblique fissures completeness was 72.8%, against 88.3% in the other group. QCTA most significant results showed a reduced post-treatment total lung volume (LV) (mean 542 ml), reduced EBV-submitted LV (700 ml) and reduced emphysema volume (331.4 ml) in the positive response group, which also showed improved functional tests. Conclusion: EBV benefit is most likely in patients who have complete interlobar fissures and develop lobar atelectasis. In patients with no radiological response we observed a higher prevalence of incomplete fissures and a greater degree of incompleteness. The fully automated QCTA detected the post-treatment alterations, especially in the treated lung analysis. (author)

  5. International Nuclear Model. Volume 3. Program description

    International Nuclear Information System (INIS)

    Andress, D.

    1985-01-01

    This is Volume 3 of three volumes of documentation of the International Nuclear Model (INM). This volume presents the Program Description of the International Nuclear Model, which was developed for the Nuclear and Alternate Fuels Division (NAFD), Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), US Department of Energy (DOE). The International Nuclear Model (INM) is a comprehensive model of the commercial nuclear power industry. It simulates economic decisions for reactor deployment and fuel management decision based on an input set of technical economic and scenario parameters. The technical parameters include reactor operating characteristics, fuel cycle timing and mass loss factors, and enrichment tails assays. Economic parameters include fuel cycle costs, financial data, and tax alternatives. INM has a broad range of scenario options covering, for example, process constraints, interregional activities, reprocessing, and fuel management selection. INM reports reactor deployment schedules, electricity generation, and fuel cycle requirements and costs. It also has specialized reports for extended burnup and permanent disposal. Companion volumes to Volume 3 are: Volume 1 - Model Overview, and Volume 2 - Data Base Relationships

  6. Petroleum supply annual 1998: Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1998 through monthly surveys. The PSA is divided into two volumes. The first volume contains three sections: Summary Statistics, Detailed Statistics, and Refinery Statistics; each with final annual data. This second volume contains final statistics for each month of 1998, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary. 35 tabs.

  7. Petroleum supply annual, 1997. Volume 2

    International Nuclear Information System (INIS)

    1998-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1997 through monthly surveys. The PSA is divided into two volumes. The first volume contains three sections: Summary Statistics, Detailed Statistics, and Refinery Statistics; each with final annual data. The second volume contains final statistics for each month of 1997, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary. 35 tabs

  8. Petroleum supply annual 1996: Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1996 through monthly surveys. The PSA is divided into two volumes. The first volume contains three sections: Summary Statistics, Detailed Statistics, and Refinery Capacity; each with final annual data. The second volume contains final statistics for each month of 1996, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary. 35 tabs.

  9. Petroleum supply annual, 1997. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1997 through monthly surveys. The PSA is divided into two volumes. The first volume contains three sections: Summary Statistics, Detailed Statistics, and Refinery Statistics; each with final annual data. The second volume contains final statistics for each month of 1997, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary. 35 tabs.

  10. Petroleum supply annual 1994, Volume 2

    International Nuclear Information System (INIS)

    1995-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1994 through annual and monthly surveys. The PSA is divided into two volumes. This first volume contains four sections: Summary Statistics, Detailed Statistics, Refinery Capacity, and Oxygenate Capacity each with final annual data. The second volume contains final statistics for each month of 1994, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary

  11. Petroleum supply annual 1996: Volume 2

    International Nuclear Information System (INIS)

    1997-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1996 through monthly surveys. The PSA is divided into two volumes. The first volume contains three sections: Summary Statistics, Detailed Statistics, and Refinery Capacity; each with final annual data. The second volume contains final statistics for each month of 1996, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary. 35 tabs

  12. Petroleum supply annual 1995: Volume 2

    International Nuclear Information System (INIS)

    1996-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1995 through monthly surveys. The PSA is divided into two volumes. This first volume contains three sections: Summary Statistics, Detailed Statistics, and selected Refinery Statistics each with final annual data. The second volume contains final statistics for each month of 1995, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary

  13. Petroleum supply annual 1998. Volume 2

    International Nuclear Information System (INIS)

    1999-06-01

    The Petroleum Supply Annual (PSA) contains information on the supply and disposition of crude oil and petroleum products. The publication reflects data that were collected from the petroleum industry during 1998 through monthly surveys. The PSA is divided into two volumes. The first volume contains three sections: Summary Statistics, Detailed Statistics, and Refinery Statistics; each with final annual data. This second volume contains final statistics for each month of 1998, and replaces data previously published in the Petroleum Supply Monthly (PSM). The tables in Volumes 1 and 2 are similarly numbered to facilitate comparison between them. Explanatory Notes, located at the end of this publication, present information describing data collection, sources, estimation methodology, data quality control procedures, modifications to reporting requirements and interpretation of tables. Industry terminology and product definitions are listed alphabetically in the Glossary. 35 tabs

  14. 24 CFR 232.630 - Assurance of completion.

    Science.gov (United States)

    2010-04-01

    ... URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE FOR NURSING HOMES, INTERMEDIATE CARE FACILITIES, BOARD AND CARE HOMES, AND ASSISTED... Fire Safety Equipment Special Requirements § 232.630 Assurance of completion. If the property upon...

  15. Thermodynamic analysis of a Stirling engine including regenerator dead volume

    Energy Technology Data Exchange (ETDEWEB)

    Puech, Pascal; Tishkova, Victoria [Universite de Toulouse, UPS, CNRS, CEMES, 29 rue Jeanne Marvig, F-31055 Toulouse (France)

    2011-02-15

    This paper provides a theoretical investigation on the thermodynamic analysis of a Stirling engine with linear and sinusoidal variations of the volume. The regenerator in a Stirling engine is an internal heat exchanger allowing to reach high efficiency. We used an isothermal model to analyse the net work and the heat stored in the regenerator during a complete cycle. We show that the engine efficiency with perfect regeneration doesn't depend on the regenerator dead volume but this dead volume strongly amplifies the imperfect regeneration effect. An analytical expression to estimate the improvement due to the regenerator has been proposed including the combined effects of dead volume and imperfect regeneration. This could be used at the very preliminary stage of the engine design process. (author)

  16. A three-dimensional gradient refocused 3D volume imaging of discoid lateral meniscus

    International Nuclear Information System (INIS)

    Araki, Yutaka; Ootani, Masatoshi; Furukawa, Tomoaki; Yamamoto, Tadatsuka; Tomoda, Kaname; Tsukaguchi, Isao; Mitomo, Masanori.

    1991-01-01

    An axial 3D volume scan with MRI was applied to the evaluation of discoid lateral meniscus of the knee. By 0.7 mm-thick thin sliced and gapless images with volume scan, characteristically elongated appearance of discoid lateral meniscus was clearly depicted. These MR findings completely accorded with those on arthroscopy. Our conclusion is that an axial 3D volume scan was essential to the diagnosis of discoid lateral meniscus. (author)

  17. 40 CFR 98.76 - Data reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... facility uses gaseous feedstock, the molar volume conversion factor of the gaseous feedstock (scf per kg... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ammonia Manufacturing § 98.76 Data reporting requirements. In...). (14) Volume of the waste recycle stream for month n for each ammonia process unit (scf) (15) Method...

  18. Trent'anni di Gran Sasso = Thirty years of Gran Sasso volume in onore di Antonino Zichichi = a volume in honour of Antonino Zichichi

    CERN Document Server

    2010-01-01

    This volume - in honour of Antonino Zichichi - is a collection of papers that have appeared in various journals, proceedings and books published by the Italian Physical Society over the last few decades about the Gran Sasso National Laboratory. The articles reproduced in the book come from Il Nuovo Saggiatore, Il Nuovo Cimento and from the Proceedings of the International School of Physics "Enrico Fermi" of Varenna. A few other relevant articles from special volumes have been included for the sake of completeness.

  19. Colloquial French the complete course for beginners

    CERN Document Server

    Demouy, Valérie

    2014-01-01

     COLLOQUIAL FRENCH is easy to use and completely up to date!Specially written by experienced teachers for self-study or class use, the course offers a step-by-step approach to written and spoken French. No prior knowledge of the language is required.What makes COLLOQUIAL FRENCH your best choice in personal language learning?Interactive - lots of exercises for regular practiceClear - concise grammar notesPractical - useful vocabulary and pronunciation guideComplete - including answer key and reference sectionWhether you''re a business traveller, or about to take up a daring challenge in adventu

  20. Target volume definition in conformal radiotherapy for prostate cancer: quality assurance in the MRC RT-01 trial

    International Nuclear Information System (INIS)

    Seddon, B.S.; Wilson, J.; Khoo, V.; Dearnaley, D.; Bidmead, M.

    2000-01-01

    Prior to randomization of patients into the UK Medical Research Council multicentre randomized trial (RT-01) of conformal radiotherapy (CFRT) in prostate cancer, clinicians at participating centres were required to complete a quality assurance (QA) clinical planning exercise to enable an investigation of inter-observer variability in gross target volume (GTV) and normal structure outlining. Thirteen participating centres and two investigators completed the clinical planning exercise of three practice planning cases. Clinicians were asked to draw outlines of the GTV, rectum and bladder on hard-copy computerized tomography (CT) films of the pelvis, which were transferred onto the Cadplan computer planning system by a single investigator. Centre, inferior and superior CT levels of GTV, rectum and bladder were noted, and volume calculations performed. Planning target volumes (PTV) were generated using automatic volume expansion of GTVs by a 1 cm margin. Anterior, right and left lateral beam eye views (BEV) of the PTVs were generated. Using a common central point, the BEV PTVs were superimposed for each beam direction of each case. Radial PTV variation was investigated by measurement of a novel parameter, termed the radial line measurement variation (RLMV). GTV central slice and length were defined with reasonable consistency. The RLMV analysis showed that the main part of the prostate gland, bladder and inferior rectum were outlined with good consistency among clinicians. However, the outlining of the prostatic apex, superior aspect of the prostate projecting into the bladder, seminal vesicles, the base of seminal vesicles and superior rectum were more variable. This exercise has demonstrated adequate consistency of GTV definition. The RLMV method of analysis indicates particular regions of clinician uncertainty. Appropriate feedback has been given to all participating clinicians, and the final RT-01 trial protocol has been modified to accommodate these findings

  1. Target volume definition for external beam partial breast radiotherapy: Clinical, pathological and technical studies informing current approaches

    International Nuclear Information System (INIS)

    Kirby, Anna M.; Coles, Charlotte E.; Yarnold, John R.

    2010-01-01

    Partial breast irradiation (PBI) is currently under investigation in several phase III trials and, following a recent consensus statement, its use off-study may increase despite ongoing uncertainty regarding optimal target volume definition. We review the clinical, pathological and technical evidence for target volume definition in external beam partial breast irradiation (EB-PBI). The optimal method of tumour bed (TB) delineation requires X-ray CT imaging of implanted excision cavity wall markers. The definition of clinical target volume (CTV) as TB plus concentric 15 mm margins is based on the anatomical distribution of multifocal and multicentric disease around the primary tumour in mastectomy specimens, and the clinical locations of local tumour relapse (LR) after breast conservation surgery. If the majority of LR originate from foci of residual invasive and/or intraduct disease in the vicinity of the TB after complete microscopic resection, CTV margin logically takes account of the position of primary tumour within the surgical resection specimen. The uncertain significance of independent primary tumours as sources of preventable LR, and of wound healing responses in stimulating LR, increases the difficulties in defining optimal CTV. These uncertainties may resolve after long-term follow-up of current PBI trials. By contrast, a commonly used 10 mm clinical to planning target volume (PTV) margin has a stronger evidence base, although departmental set-up errors need to be confirmed locally. A CTV-PTV margin >10 mm may be required in women with larger breasts and/or large seromas, whilst the role of image-guided radiotherapy with or without TB markers in reducing CTV-PTV margins needs to be explored.

  2. Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

    Science.gov (United States)

    Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

    2017-10-01

    In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

  3. 7 CFR 981.51 - Requirements for reserve.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Requirements for reserve. 981.51 Section 981.51... Regulating Handling Volume Regulation § 981.51 Requirements for reserve. Each handler may satisfy his reserve... include grade requirements for reserve almonds delivered to human consumption outlets. [41 FR 26853, June...

  4. Toward unstained cytology and complete blood counts at the point of care (Conference Presentation)

    Science.gov (United States)

    Zuluaga, Andres F.; Pierce, Mark C.; MacAulay, Calum E.

    2017-02-01

    Cytology tests, whether performed on body fluids, aspirates, or scrapings are commonly used to detect, diagnose, and monitor a wide variety of health conditions. Complete blood counts (CBCs) quantify the number of red and white blood cells in a blood volume, as well as the different types of white blood cells. There is a critical unmet need for an instrument that can perform CBCs at the point of care (POC), and there is currently no product in the US that can perform this test at the bedside. We have developed a system that is capable of tomographic images with sub-cellular resolution with consumer-grade broadband (LED) sources and CMOS detectors suitable for POC implementation of CBC tests. The systems consists of cascaded static Michelson and Sagnac interferometers that map phase (encoding depth) and a transverse spatial dimension onto a two-dimensional output plane. Our approach requires a 5 microliter sample, can be performed in 5 minutes or less, and does not require staining or other processing as it relies on intrinsic contrast. We will show results directly imaging and differentiating unstained blood cells using supercontinuum fiber lasers and LEDs as sources and CMOS cameras as sensors. We will also lay out the follow up steps needed, including image segmentation, analysis and classification, to verify performance and advance toward CBCs that can be performed bedside and do not require CLIA-certified laboratories.

  5. The design, development, and test of balloonborne and groundbased lidar systems. Volume 3: Groundbased lidar systems

    Science.gov (United States)

    Shepherd, O.; Aurilio, G.; Bucknam, R. D.; Hurd, A. G.; Robertie, N. F.

    1991-06-01

    This is Volume 3 of a three volume final report on the design, development and test of balloonborne and groundbased lidar systems. Volume 1 describes the design and fabrication of a balloonborne CO2 coherent payload to measure the 10.6 micrometers backscatter from atmospheric aerosols as a function of altitude. Volume 2 describes the August 1987 flight test of Atmospheric Balloonborne Lidar Experiment, ABLE 2. In this volume we describe groundbased lidar development and measurements. A design was developed for installation of the ABLE lidar in the GL rooftop dome. A transportable shed was designed to house the ABLE lidar at the various remote measurement sites. Refurbishment and modification of the ABLE lidar were completed to permit groundbased lidar measurements of clouds and aerosols. Lidar field measurements were made at Ascension Island during SABLE 89. Lidar field measurements were made at Terciera, Azores during GABLE 90. These tasks have been successfully completed, and recommendations for further lidar measurements and data analysis have been made.

  6. COMPLETE SUPPRESSION OF THE M/N = 2/1 NEOCLASSICAL TEARING MODE USING RADIALLY LOCALIZED ELECTRON CYCLOTRON CURRENT DRIVE ON DIII-D AND THE REQUIREMENTS FOR ITER

    International Nuclear Information System (INIS)

    LAHAYE, RJ; LUCE, TC; PETTY, CC; HUMPHREYS, DA; HYATT, AW; PERKINS, FW; PRATER, R; STRAIT, EJ; WADE, MR

    2003-01-01

    A271 COMPLETE SUPPRESSION OF THE M/N = 2/1 NEOCLASSICAL TEARING MODE USING RADIALLY LOCALIZED ELECTRON CYCLOTRON CURRENT DRIVE ON DIII-D AND THE REQUIREMENTS FOR ITER. DIII-D experiments demonstrate the first real-time feedback control of the relative location of a narrow beam of microwaves to completely suppress and eliminate a growing tearing mode at the q = 2 surface. long wavelength tearing modes such as the m/n = 2/1 instability are particularly deleterious to tokamak operation. Confinement is seriously degraded by the island, plasma rotation can cease (mode-lock) and disruption can occur. The neoclassical tearing mode (NTM) becomes unstable due to the presence of a helically-perturbed bootstrap current and can be stabilized by replacing the missing bootstrap current in the island O-point by precisely located co-electron cyclotron current drive (ECCD). The optimum position is found when the DIII-D plasma control system (PCS) is put into a search and suppress mode that makes small radial shifts (in about 1 cm steps) in the ECCD location based on minimizing the Mirnov amplitude. Requirements for ITER are addressed

  7. 38 CFR 3.375 - Determination of inactivity (complete arrest) in tuberculosis.

    Science.gov (United States)

    2010-07-01

    ... inactivity (complete arrest) in tuberculosis. 3.375 Section 3.375 Pensions, Bonuses, and Veterans' Relief...) in tuberculosis. (a) Pulmonary tuberculosis. A veteran shown to have had pulmonary tuberculosis will...) Nonpulmonary disease. Determination of complete arrest of nonpulmonary tuberculosis requires absence of...

  8. Zeroth-order design report for the next linear collider. Volume 2

    International Nuclear Information System (INIS)

    Raubenheimer, T.O.

    1996-05-01

    This Zeroth-Order Design Report (ZDR) for the Next Linear Collider (NLC) has been completed as a feasibility study for a TeV-scale linear collider that incorporates a room-temperature accelerator powered by rf microwaves at 11.424 GHz--similar to that presently used in the SLC, but at four times the rf frequency. The purpose of this study is to examine the complete systems of such a collider, to understand how the parts fit together, and to make certain that every required piece has been included. The ''design'' presented here is not fully engineered in any sense, but to be assured that the NLC can be built, attention has been given to a number of critical components and issues that present special challenges. More engineering and development of a number of mechanical and electrical systems remain to be done, but the conclusion of this study is that indeed the NLC is technically feasible and can be expected to reach the performance levels required to perform research at the TeV energy scale. Volume II covers the following: collimation systems; IP switch and big bend; final focus; the interaction region; multiple bunch issues; control systems; instrumentation; machine protection systems; NLC reliability considerations; NLC conventional facilities. Also included are four appendices on the following topics: An RF power source upgrade to the NLC; a second interaction region for gamma-gamma, gamma-electron; ground motion: theory and measurement; and beam-based feedback: theory and implementation

  9. Zeroth-order design report for the next linear collider. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Raubenheimer, T.O. [ed.

    1996-05-01

    This Zeroth-Order Design Report (ZDR) for the Next Linear Collider (NLC) has been completed as a feasibility study for a TeV-scale linear collider that incorporates a room-temperature accelerator powered by rf microwaves at 11.424 GHz--similar to that presently used in the SLC, but at four times the rf frequency. The purpose of this study is to examine the complete systems of such a collider, to understand how the parts fit together, and to make certain that every required piece has been included. The ``design`` presented here is not fully engineered in any sense, but to be assured that the NLC can be built, attention has been given to a number of critical components and issues that present special challenges. More engineering and development of a number of mechanical and electrical systems remain to be done, but the conclusion of this study is that indeed the NLC is technically feasible and can be expected to reach the performance levels required to perform research at the TeV energy scale. Volume II covers the following: collimation systems; IP switch and big bend; final focus; the interaction region; multiple bunch issues; control systems; instrumentation; machine protection systems; NLC reliability considerations; NLC conventional facilities. Also included are four appendices on the following topics: An RF power source upgrade to the NLC; a second interaction region for gamma-gamma, gamma-electron; ground motion: theory and measurement; and beam-based feedback: theory and implementation.

  10. Effects of gestational age on brain volume and cognitive functions in generally healthy very preterm born children during school-age: A voxel-based morphometry study.

    Directory of Open Access Journals (Sweden)

    Sakari Lemola

    Full Text Available To determine whether the relationship of gestational age (GA with brain volumes and cognitive functions is linear or whether it follows a threshold model in preterm and term born children during school-age.We studied 106 children (M = 10 years 1 month, SD = 16 months; 40 females enrolled in primary school: 57 were healthy very preterm children (10 children born 24-27 completed weeks' gestation (extremely preterm, 14 children born 28-29 completed weeks' gestation, 19 children born 30-31 completed weeks' gestation (very preterm, and 14 born 32 completed weeks' gestation (moderately preterm all born appropriate for GA (AGA and 49 term-born children. Neuroimaging involved voxel-based morphometry with the statistical parametric mapping software. Cognitive functions were assessed with the WISC-IV. General Linear Models and multiple regressions were conducted controlling age, sex, and maternal education.Compared to groups of children born 30 completed weeks' gestation and later, children born <28 completed weeks' gestation had less gray matter volume (GMV and white matter volume (WMV and poorer cognitive functions including decreased full scale IQ, and processing speed. Differences in GMV partially mediated the relationship between GA and full scale IQ in preterm born children.In preterm children who are born AGA and without major complications GA is associated with brain volume and cognitive functions. In particular, decreased brain volume becomes evident in the extremely preterm group (born <28 completed weeks' gestation. In preterm children born 30 completed weeks' gestation and later the relationship of GA with brain volume and cognitive functions may be less strong as previously thought.

  11. Effects of plyometric training volume and training surface on explosive strength.

    Science.gov (United States)

    Ramírez-Campillo, Rodrigo; Andrade, David C; Izquierdo, Mikel

    2013-10-01

    The purpose of this study is to examine the effects of different volume and training surfaces during a short-term plyometric training program on neuromuscular performance. Twenty-nine subjects were randomly assigned to 4 groups: control group (CG, n = 5), moderate volume group (MVG, n = 9, 780 jumps), moderate volume hard surface group (MVGHS, n = 8, 780 jumps), and high volume group (HVG, n = 7, 1,560 jumps). A series of tests were performed by the subjects before and after 7 weeks of plyometric training. These tests were measurement of maximum strength (5 maximum repetitions [5RMs]), drop jumps (DJs) of varying heights (20, 40, and 60 cm), squat and countermovement jumps (SJ and CMJ, respectively), timed 20-m sprint, agility, body weight, and height. The results of the present study suggest that high training volume leads to a significant increase in explosive performance that requires fast stretch-shortening cycle (SSC) actions (such as DJ and sprint) in comparison to what is observed after a moderate training volume regimen. Second, when plyometric training is performed on a hard training surface (high-impact reaction force), a moderate training volume induces optimal stimulus to increase explosive performance requiring fast SSC actions (e.g., DJ), maximal dynamic strength enhancement, and higher training efficiency. Thus, a finding of interest in the study was that after 7 weeks of plyometric training, performance enhancement in maximal strength and in actions requiring fast SSC (such as DJ and sprint) were dependent on the volume of training and the surface on which it was performed. This must be taken into account when using plyometric training on different surfaces.

  12. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 10. Repository preconceptual design studies: granite

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Volume 10 ''Repository Preconceptual Design Studies: Granite,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This document describes a preconceptual design for a nuclear waste storage facility in granite. The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area, and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/11, ''Drawings for Repository Preconceptual Design Studies: Granite.''

  13. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 8. Repository preconceptual design studies: salt

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Volume 8 ''Repository Preconceptual Design Studies: Salt,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This document describes a preconceptual design for a nuclear waste storage facility in salt. The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area, and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/9, ''Drawings for Repository Preconceptual Design Studies: Salt.''

  14. [Target volume margins for lung cancer: internal target volume/clinical target volume].

    Science.gov (United States)

    Jouin, A; Pourel, N

    2013-10-01

    The aim of this study was to carry out a review of margins that should be used for the delineation of target volumes in lung cancer, with a focus on margins from gross tumour volume (GTV) to clinical target volume (CTV) and internal target volume (ITV) delineation. Our review was based on a PubMed literature search with, as a cornerstone, the 2010 European Organisation for Research and Treatment of Cancer (EORTC) recommandations by De Ruysscher et al. The keywords used for the search were: radiotherapy, lung cancer, clinical target volume, internal target volume. The relevant information was categorized under the following headings: gross tumour volume definition (GTV), CTV-GTV margin (first tumoural CTV then nodal CTV definition), in field versus elective nodal irradiation, metabolic imaging role through the input of the PET scanner for tumour target volume and limitations of PET-CT imaging for nodal target volume definition, postoperative radiotherapy target volume definition, delineation of target volumes after induction chemotherapy; then the internal target volume is specified as well as tumoural mobility for lung cancer and respiratory gating techniques. Finally, a chapter is dedicated to planning target volume definition and another to small cell lung cancer. For each heading, the most relevant and recent clinical trials and publications are mentioned. Copyright © 2013. Published by Elsevier SAS.

  15. Safety of magnetic fusion facilities: Volume 2, Guidance

    International Nuclear Information System (INIS)

    1995-01-01

    This document provides guidance for the implementation of the requirements identified in Vol. 1 of this Standard. This guidance is intended for the managers, designers, operators, and other personnel with safety responsibilities for facilities designated as magnetic fusion facilities. While Vol. 1 is generally applicable in that requirements there apply to a wide range of fusion facilities, this volume is concerned mainly with large facilities such as the International Thermonuclear Experimental Reactor (ITER). Using a risk-based prioritization, the concepts presented here may also be applied to other magnetic fusion facilities. This volume is oriented toward regulation in the Department of Energy (DOE) environment

  16. Los Alamos National Laboratory Meteorology Monitoring Program: 2016 Data Completeness/ Quality Report

    Energy Technology Data Exchange (ETDEWEB)

    Bruggeman, David Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-06-15

    This report summarizes data completeness by tower and by instrument for 2016 and compares that data with the Los Alamos National Laboratory (LANL) and American National Standards Institute (ANSI) 2015 standards. This report is designed to make data users aware of data completeness and any data quality issues. LANL meteorology monitoring goals include 95% completeness for all measurements. The ANSI 2015 standard requires 90% completeness for all measurements. This report documents instrument/tower issues as they impact data completeness.

  17. Guidance and Control Software Project Data - Volume 1: Planning Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the planning documents from the GCS project. Volume 1 contains five appendices: A. Plan for Software Aspects of Certification for the Guidance and Control Software Project; B. Software Development Standards for the Guidance and Control Software Project; C. Software Verification Plan for the Guidance and Control Software Project; D. Software Configuration Management Plan for the Guidance and Control Software Project; and E. Software Quality Assurance Activities.

  18. Guidance and Control Software Project Data - Volume 3: Verification Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes the verification documents from the GCS project. Volume 3 contains four appendices: A. Software Verification Cases and Procedures for the Guidance and Control Software Project; B. Software Verification Results for the Pluto Implementation of the Guidance and Control Software; C. Review Records for the Pluto Implementation of the Guidance and Control Software; and D. Test Results Logs for the Pluto Implementation of the Guidance and Control Software.

  19. Computing the partial volume of pressure vessels

    Energy Technology Data Exchange (ETDEWEB)

    Wiencke, Bent [Nestle USA, Corporate Engineering, 800 N. Brand Blvd, Glendale, CA 91203 (United States)

    2010-06-15

    The computation of the partial and total volume of pressure vessels with various type of head profiles requires detailed knowledge of the head profile geometry. Depending on the type of head profile the derivation of the equations can become very complex and the calculation process cumbersome. Certain head profiles require numerical methods to obtain the partial volume, which for most application is beyond the scope of practicability. This paper suggests a unique method that simplifies the calculation procedure for the various types of head profiles by using one common set of equations without the need for numerical or complex computation methods. For ease of use, all equations presented in this paper are summarized in a single table format for horizontal and vertical vessels. (author)

  20. Completion of treatment planning

    International Nuclear Information System (INIS)

    Lief, Eugene

    2008-01-01

    The outline of the lecture included the following topics: entering prescription; plan printout; print and transfer DDR; segment BEV; export to R and V; physician approval; and second check. Considerable attention, analysis and discussion. The summary is as follows: Treatment planning completion is a very responsible process which requires maximum attention; Should be independently checked by the planner, physicist, radiation oncologist and a therapist; Should not be done in a last minute rush; Proper communication between team members; Properly set procedure should prevent propagation of an error by one individual to the treatment: the error should be caught by somebody else. (P.A.)

  1. Fuel Rod Consolidation Project: Phase 2, Final report: Volume 2, Appendices

    International Nuclear Information System (INIS)

    1987-01-01

    This document, Volume 2, provides the appendices to Volume 1 of the Fuel Rod Consolidation Project. It provides information on the following: References; Trade-off Studies; Instrument List; RAM Data; Fabrication Specifications; Software Specifications; and Design Requirements

  2. Design requirements for SRB production control system. Volume 2: System requirements and conceptual description

    Science.gov (United States)

    1981-01-01

    In the development of the business system for the SRB automated production control system, special attention had to be paid to the unique environment posed by the space shuttle. The issues posed by this environment, and the means by which they were addressed, are reviewed. The change in management philosphy which will be required as NASA switches from one-of-a-kind launches to multiple launches is discussed. The implications of the assembly process on the business system are described. These issues include multiple missions, multiple locations and facilities, maintenance and refurbishment, multiple sources, and multiple contractors. The implications of these aspects on the automated production control system are reviewed including an assessment of the six major subsystems, as well as four other subsystem. Some general system requirements which flow through the entire business system are described.

  3. Completed Research in Health, Physical Education, Recreation & Dance; Including International Sources. Volume 27. 1985 Edition.

    Science.gov (United States)

    Freedson, Patty S., Ed.

    This compilation lists research completed in the areas of health, physical education, recreation, dance, and allied areas during 1984. The document is arranged in two parts. In the index, references are arranged under the subject headings in alphabetical order. Abstracts of master's and doctor's theses from institutions offering graduate programs…

  4. Access to Four-Year Public Colleges and Degree Completion

    OpenAIRE

    Joshua Goodman; Michael Hurwitz; Jonathan Smith

    2015-01-01

    Does access to four-year colleges affect degree completion for students who would otherwise attend two-year colleges? Admission to Georgia’s four-year public sector requires minimum SAT scores. Regression discontinuity estimates show that access to this sector increases four-year college enrollment and college quality, largely by diverting students from two-year colleges. Access substantially increases bachelor’s degree completion rates for these relatively low-skilled students. SAT retaking ...

  5. Concatenated image completion via tensor augmentation and completion

    OpenAIRE

    Bengua, Johann A.; Tuan, Hoang D.; Phien, Ho N.; Do, Minh N.

    2016-01-01

    This paper proposes a novel framework called concatenated image completion via tensor augmentation and completion (ICTAC), which recovers missing entries of color images with high accuracy. Typical images are second- or third-order tensors (2D/3D) depending if they are grayscale or color, hence tensor completion algorithms are ideal for their recovery. The proposed framework performs image completion by concatenating copies of a single image that has missing entries into a third-order tensor,...

  6. Waste-aware fluid volume assignment for flow-based microfluidic biochips

    DEFF Research Database (Denmark)

    Schneider, Alexander Rüdiger; Pop, Paul; Madsen, Jan

    2017-01-01

    complex Fluidic Units (FUs) such as switches, micropumps, mixers and separators can be constructed. When running a biochemical application on a FBMB, fluid volumes are dispensed from input reservoirs and used by the FUs. Given a biochemical application and a biochip, we are interested in determining...... the fluid volume assignment for each operation of the application, such that the FUs volume requirements are satisfied, while over- and underflow are avoided and the total volume of fluid used is minimized. We propose an algorithm for this fluid assignment problem. Compared to previous work, our method...

  7. Waste Retrieval Sluicing System Campaign Number 3 Solids Volume Transferred Calculation

    International Nuclear Information System (INIS)

    CAROTHERS, K.G.

    1999-01-01

    Waste Retrieval Sluicing System (WRSS) operations at tank 241-C-106 began on Wednesday, November 18, 1998. The purpose of this system is to retrieve and transfer the high-heat sludge from the tank for storage in double-shell tank 241-AY-102, thereby resolving the high-heat safety issue for the tank, and to demonstrate modernized past-practice retrieval technology for single-shell tank waste. Performance Agreement (PA) TWR 1.2.2, C-106 Sluicing, was established by the Department of Energy, Office of River Protection (ORP) for achieving completion of sluicing retrieval of waste from tank 241-C-106 by September 30, 1999. This level of sludge removal is defined in the PA as either removal of approximately 72 inches of sludge or removal of 172,000 gallons of sludge (approximately 62 inches) and less than 6,000 gallons (approximately 2 inches) of sludge removal per 12 hour sluice batch for three consecutive batches. Preliminary calculations of the volume of tank 241-C-106 sludge removed as of September 29, 1999 were provided to ORP documenting completion of PA TWR 1.2.2 (Allen 1999a). The purpose of this calculation is to document the final sludge volume removed from tank 241-C-106 up through September 30, 1999. Additionally, the results of an extra batch completed October 6, 1999 is included to show the total volume of sludge removed through the end of WRSS operations. The calculation of the sludge volume transferred from the tank is guided by engineering procedure HNF-SD-WM-PROC-021, Section 15.0,Rev. 3, sub-section 4.4, ''Calculation of Sludge Transferred.''

  8. Waste Retrieval Sluicing System Campaign Number 3 Solids Volume Transferred Calculation

    International Nuclear Information System (INIS)

    CAROTHERS, K.G.

    1999-01-01

    Waste Retrieval Sluicing System (WRSS) operations at tank 241-C-106 began on Wednesday, November 18,1998. The purpose of this system is to retrieve and transfer the high-heat sludge from the tank for storage in double-shell tank 241-AY-102, thereby resolving the high-heat safety issue for the tank, and to demonstrate modernized past-practice retrieval technology for single-shell tank waste. Performance Agreement (PA) TWR 1.2.2, C-106 Sluicing, was established by the Department of Energy, Office of River Protection (ORP) for achieving completion of sluicing retrieval of waste from tank 241-C-106 by September 30,1999. This level of sludge removal is defined in the PA as either removal of approximately 72 inches of sludge or removal of 172,000 gallons of sludge (approximately 62 inches) and less than 6,000 gallons (approximately 2 inches) of sludge removal per 12 hour sluice batch for three consecutive batches. Preliminary calculations of the volume of tank 241-C-106 sludge removed as of September 29, 1999 were provided to ORP documenting completion of PA TWR 1.2.2 (Allen 1999a). The purpose of this calculation is to document the final sludge volume removed from tank 241-C-106 up through September 30, 1999. Additionally, the results of an extra batch completed October 6, 1999 is included to show the total volume of sludge removed through the end of WRSS operations. The calculation of the sludge volume transferred from the tank is guided by engineering procedure HNF-SD-WM-PROC-021, Section 15.0,Rev. 3, sub-section 4.4, ''Calculation of Sludge Transferred.''

  9. Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias.

    Science.gov (United States)

    Waugh, Jeff L; Kuster, John K; Levenstein, Jacob M; Makris, Nikos; Multhaupt-Buell, Trisha J; Sudarsky, Lewis R; Breiter, Hans C; Sharma, Nutan; Blood, Anne J

    2016-01-01

    Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia. We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM) to compare regional volume between matched healthy controls and patients with idiopathic primary focal dystonia (cervical, n = 17, laryngeal, n = 7). We used (1) automated gross volume measures of eight motor control regions using the FreeSurfer analysis package; (2) blinded, anatomist-supervised manual segmentation of the whole thalamus (also gross volume); and (3) voxel based morphometry, which measures local T1-weighted signal intensity and estimates gray matter density or volume at the level of single voxels, for both whole-brain and thalamus. Using both automated and manual gross volumetry, we found a significant volume decrease only in the thalamus in two focal dystonias. Decreases in whole-thalamic volume were independent of head and brain size, laterality of symptoms, and duration. VBM measures did not differ between dystonia and control groups in any motor control region. Reduced thalamic gross volume, detected in two independent analyses, suggests a common anatomical abnormality in cervical dystonia and spasmodic dysphonia. Defining the structural underpinnings of dystonia may require such complementary approaches.

  10. Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias.

    Directory of Open Access Journals (Sweden)

    Jeff L Waugh

    Full Text Available Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia.We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM to compare regional volume between matched healthy controls and patients with idiopathic primary focal dystonia (cervical, n = 17, laryngeal, n = 7. We used (1 automated gross volume measures of eight motor control regions using the FreeSurfer analysis package; (2 blinded, anatomist-supervised manual segmentation of the whole thalamus (also gross volume; and (3 voxel based morphometry, which measures local T1-weighted signal intensity and estimates gray matter density or volume at the level of single voxels, for both whole-brain and thalamus.Using both automated and manual gross volumetry, we found a significant volume decrease only in the thalamus in two focal dystonias. Decreases in whole-thalamic volume were independent of head and brain size, laterality of symptoms, and duration. VBM measures did not differ between dystonia and control groups in any motor control region.Reduced thalamic gross volume, detected in two independent analyses, suggests a common anatomical abnormality in cervical dystonia and spasmodic dysphonia. Defining the structural underpinnings of dystonia may require such complementary approaches.

  11. Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias

    Science.gov (United States)

    Waugh, Jeff L.; Kuster, John K.; Levenstein, Jacob M.; Makris, Nikos; Multhaupt-Buell, Trisha J.; Sudarsky, Lewis R.; Breiter, Hans C.; Sharma, Nutan; Blood, Anne J.

    2016-01-01

    Background Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia. Methods We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM) to compare regional volume between matched healthy controls and patients with idiopathic primary focal dystonia (cervical, n = 17, laryngeal, n = 7). We used (1) automated gross volume measures of eight motor control regions using the FreeSurfer analysis package; (2) blinded, anatomist-supervised manual segmentation of the whole thalamus (also gross volume); and (3) voxel based morphometry, which measures local T1-weighted signal intensity and estimates gray matter density or volume at the level of single voxels, for both whole-brain and thalamus. Results Using both automated and manual gross volumetry, we found a significant volume decrease only in the thalamus in two focal dystonias. Decreases in whole-thalamic volume were independent of head and brain size, laterality of symptoms, and duration. VBM measures did not differ between dystonia and control groups in any motor control region. Conclusions Reduced thalamic gross volume, detected in two independent analyses, suggests a common anatomical abnormality in cervical dystonia and spasmodic dysphonia. Defining the structural underpinnings of dystonia may require such complementary approaches. PMID:27171035

  12. Micro analysis of fringe field formed inside LDA measuring volume

    International Nuclear Information System (INIS)

    Ghosh, Abhijit; Nirala, A K

    2016-01-01

    In the present study we propose a technique for micro analysis of fringe field formed inside laser Doppler anemometry (LDA) measuring volume. Detailed knowledge of the fringe field obtained by this technique allows beam quality, alignment and fringe uniformity to be evaluated with greater precision and may be helpful for selection of an appropriate optical element for LDA system operation. A complete characterization of fringes formed at the measurement volume using conventional, as well as holographic optical elements, is presented. Results indicate the qualitative, as well as quantitative, improvement of fringes formed at the measurement volume by holographic optical elements. Hence, use of holographic optical elements in LDA systems may be advantageous for improving accuracy in the measurement. (paper)

  13. Late Noachian fluvial erosion on Mars: Cumulative water volumes required to carve the valley networks and grain size of bed-sediment

    Science.gov (United States)

    Rosenberg, Eliott N.; Head, James W., III

    2015-11-01

    Our goal is to quantify the cumulative water volume that was required to carve the Late Noachian valley networks on Mars. We employ an improved methodology in which fluid/sediment flux ratios are based on empirical data, not assumed. We use a large quantity of data from terrestrial rivers to assess the variability of actual fluid/sediment flux sediment ratios. We find the flow depth by using an empirical relationship to estimate the fluid flux from the estimated channel width, and then using estimated grain sizes (theoretical sediment grain size predictions and comparison with observations by the Curiosity rover) to find the flow depth to which the resulting fluid flux corresponds. Assuming that the valley networks contained alluvial bed rivers, we find, from their current slopes and widths, that the onset of suspended transport occurs near the sand-gravel boundary. Thus, any bed sediment must have been fine gravel or coarser, whereas fine sediment would be carried downstream. Subsequent to the cessation of fluvial activity, aeolian processes have partially redistributed fine-grain particles in the valleys, often forming dunes. It seems likely that the dominant bed sediment size was near the threshold for suspension, and assuming that this was the case could make our final results underestimates, which is the same tendency that our other assumptions have. Making this assumption, we find a global equivalent layer (GEL) of 3-100 m of water to be the most probable cumulative volume that passed through the valley networks. This value is similar to the ∼34 m water GEL currently on the surface and in the near-surface in the form of ice. Note that the amount of water required to carve the valley networks could represent the same water recycled through a surface valley network hydrological system many times in separate or continuous precipitation/runoff/collection/evaporation/precipitation cycles.

  14. Drusen Volume and Retinal Pigment Epithelium Abnormal Thinning Volume Predict 2-Year Progression of Age-Related Macular Degeneration.

    Science.gov (United States)

    Folgar, Francisco A; Yuan, Eric L; Sevilla, Monica B; Chiu, Stephanie J; Farsiu, Sina; Chew, Emily Y; Toth, Cynthia A

    2016-01-01

    To analyze the value of novel measures of retinal pigment epithelium-drusen complex (RPEDC) volume to predict 2-year disease progression of intermediate age-related macular degeneration (AMD). Prospective, observational study. Three hundred forty-five AMD and 122 non-AMD participants enrolled in the Age Related Eye Disease Study 2 Ancillary Spectral-Domain (SD) Optical Coherence Tomography (OCT) study. High-density SD OCT macular volumes were obtained at yearly study visits. The RPEDC abnormal thickening (henceforth, OCT drusen) and RPEDC abnormal thinning (RAT) volumes were generated by semiautomated segmentation of total RPEDC within a 5-mm-diameter macular field. Volume change and odds ratio (OR) with 95% confidence intervals (CI) for progression to advanced AMD with choroidal neovascularization (CNV) or central geographic atrophy (GA). Complete volumes were obtained in 265 and 266 AMD eyes and in 115 and 97 control eyes at baseline and at year 2, respectively. In AMD eyes, mean (standard deviation) OCT drusen volume increased from 0.08 mm(3) (0.16 mm(3)) to 0.10 mm(3) (0.23 mm(3); P < 0.001), and RAT volume increased from 8.3 × 10(-4) mm(3) (20.8 × 10(-4) mm(3)) to 18.4 × 10(-4) mm(3) (46.6 × 10(-4) mm(3); P < 0.001). Greater baseline OCT drusen volume was associated with 2-year progression to CNV (P = 0.002). Odds of developing CNV increased by 31% for every 0.1-mm(3) increase in baseline OCT drusen volume (OR, 1.31; 95% CI, 1.06-1.63; P = 0.013). Greater baseline RAT volume was associated with significant 2-year increase in RAT volume (P < 0.001), noncentral GA (P < 0.001), and progression to central GA (P < 0.001). Odds of developing central GA increased by 32% for every 0.001-mm(3) increase in baseline RAT volume (OR, 1.32; 95% CI, 1.14-1.53; P < 0.001). In non-AMD eyes, all volumes were significantly lower than AMD eyes and showed no significant 2-year change. Macular OCT drusen and RAT volumes increased significantly in AMD eyes over 2 years

  15. High integrity software for nuclear power plants: Candidate guidelines, technical basis and research needs. Executive summary: Volume 1

    International Nuclear Information System (INIS)

    Seth, S.; Bail, W.; Cleaves, D.; Cohen, H.; Hybertson, D.; Schaefer, C.; Stark, G.; Ta, A.; Ulery, B.

    1995-06-01

    The work documented in this report was performed in support of the US Nuclear Regulatory Commission to examine the technical basis for candidate guidelines that could be considered in reviewing and evaluating high integrity computer software used in the safety systems of nuclear power plants. The framework for the work consisted of the following software development and assurance activities: requirements specification; design; coding; verification and validation, including static analysis and dynamic testing; safety analysis; operation and maintenance; configuration management; quality assurance; and planning and management. Each activity (framework element) was subdivided into technical areas (framework subelements). The report describes the development of approximately 200 candidate guidelines that span the entire range of software life-cycle activities; the assessment of the technical basis for those candidate guidelines; and the identification, categorization and prioritization of research needs for improving the technical basis. The report has two volumes: Volume 1, Executive Summary, includes an overview of the framework and of each framework element, the complete set of candidate guidelines, the results of the assessment of the technical basis for each candidate guideline, and a discussion of research needs that support the regulatory function; Volume 2 is the main report

  16. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 21. Ground water movement and nuclide transport

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-04-01

    This volume, TM-36/21 Ground Water Movement and Nuclide Transport, is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations, Y/OWI/TM-36'' which supplements a ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations, Y/OWI/TM-44.'' The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling of spent fuel and uranium-only recycling. The studies presented in this volume consider the effect of the construction of the repository and the consequent heat generation on the ground water movement. Additionally, the source concentrations and leach rates of selected radionuclides were studied in relation to the estimated ground water inflow rates. Studies were also performed to evaluate the long term migration of radionuclides as affected by the ground water flow. In all these studies, three geologic environments are considered; granite, shale and basalt.

  17. Free volume from positron lifetime and pressure-volume-temperature experiments in relation to structural relaxation of van der Waals molecular glass-forming liquids.

    Science.gov (United States)

    Dlubek, G; Shaikh, M Q; Rätzke, K; Paluch, M; Faupel, F

    2010-06-16

    Positron annihilation lifetime spectroscopy (PALS) is employed to characterize the temperature dependence of the free volume in two van der Waals liquids: 1, 1'-bis(p-methoxyphenyl)cyclohexane (BMPC) and 1, 1'-di(4-methoxy-5-methylphenyl)cyclohexane (BMMPC). From the PALS spectra analysed with the routine LifeTime9.0, the size (volume) distribution of local free volumes (subnanometer size holes), its mean, [v(h)], and mean dispersion, σ(h), were calculated. A comparison with the macroscopic volume from pressure-volume-temperature (PV T) experiments delivered the hole density and the specific hole free volume and a complete characterization of the free volume microstructure in that sense. These data are used in correlation with structural (α) relaxation data from broad-band dielectric spectroscopy (BDS) in terms of the Cohen-Grest and Cohen-Turnbull free volume models. An extension of the latter model allows us to quantify deviations between experiments and theory and an attempt to systematize these in terms of T(g) or of the fragility. The experimental data for several fragile and less fragile glass formers are involved in the final discussion. It was concluded that, for large differences in the fragility of different glass formers, the positron lifetime mirrors clearly the different character of these materials. For small differences in the fragility, additional properties like the character of bonds and chemical structure of the material may affect size, distribution and thermal behaviour of the free volume.

  18. Free volume from positron lifetime and pressure-volume-temperature experiments in relation to structural relaxation of van der Waals molecular glass-forming liquids

    Energy Technology Data Exchange (ETDEWEB)

    Dlubek, G [ITA Institute for Innovative Technologies, Koethen/Halle, Wiesenring 4, D-06120 Lieskau (Germany); Shaikh, M Q; Raetzke, K; Faupel, F [Faculty of Engineering, Institute for Materials Science, Christian-Albrechts University of Kiel, Kaiserstrasse 2, D-24143 Kiel (Germany); Paluch, M, E-mail: guenter.dlubek@gmx.d [Institute of Physics, Silesian University, Uniwersytecka 4, 40-007 Katowice (Poland)

    2010-06-16

    Positron annihilation lifetime spectroscopy (PALS) is employed to characterize the temperature dependence of the free volume in two van der Waals liquids: 1, 1'-bis(p-methoxyphenyl)cyclohexane (BMPC) and 1, 1'-di(4-methoxy-5-methylphenyl)cyclohexane (BMMPC). From the PALS spectra analysed with the routine LifeTime9.0, the size (volume) distribution of local free volumes (subnanometer size holes), its mean, (v{sub h}), and mean dispersion, {sigma}{sub h}, were calculated. A comparison with the macroscopic volume from pressure-volume-temperature (PV T) experiments delivered the hole density and the specific hole free volume and a complete characterization of the free volume microstructure in that sense. These data are used in correlation with structural ({alpha}) relaxation data from broad-band dielectric spectroscopy (BDS) in terms of the Cohen-Grest and Cohen-Turnbull free volume models. An extension of the latter model allows us to quantify deviations between experiments and theory and an attempt to systematize these in terms of T{sub g} or of the fragility. The experimental data for several fragile and less fragile glass formers are involved in the final discussion. It was concluded that, for large differences in the fragility of different glass formers, the positron lifetime mirrors clearly the different character of these materials. For small differences in the fragility, additional properties like the character of bonds and chemical structure of the material may affect size, distribution and thermal behaviour of the free volume.

  19. The KamLAND full-volume calibration system

    Energy Technology Data Exchange (ETDEWEB)

    Berger, B E [Department of Physics, Colorado State University, Fort Collins, Colorado 80523 (United States); Busenitz, J; Classen, T; Keefer, G; McKee, D; Piepke, A [Department of Physics and Astronomy, University of Alabama, Tuscaloosa, Alabama 35487 (United States); Decowski, M P; Elor, G; Frank, A; Freedman, S J; Fujikawa, B K; Galloway, M; Gray, F; Hsu, L; Ichimura, K; Kadel, R; Lendvai, C; O' Donnell, T [Physics Department, University of California, Berkeley and Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Dwyer, D A [W. K. Kellogg Radiation Laboratory, California Institute of Technology, Pasadena, California 91125 (United States); Heeger, K M [Department of Physics, University of Wisconsin, Madison, Wisconsin 53706 (United States)] (and others)

    2009-04-15

    We have successfully built and operated a source deployment system for the KamLAND detector. This system was used to position radioactive sources throughout the delicate 1-kton liquid scintillator volume, while meeting stringent material cleanliness, material compatibility, and safety requirements. The calibration data obtained with this device were used to fully characterize detector position and energy reconstruction biases. As a result, the uncertainty in the size of the detector fiducial volume was reduced by a factor of two. Prior to calibration with this system, the fiducial volume was the largest source of systematic uncertainty in measuring the number of antineutrinos detected by KamLAND. This paper describes the design, operation and performance of this unique calibration system.

  20. The KamLAND Full-Volume Calibration System

    Energy Technology Data Exchange (ETDEWEB)

    KamLAND Collaboration; Berger, B. E.; Busenitz, J.; Classen, T.; Decowski, M. P.; Dwyer, D. A.; Elor, G.; Frank, A.; Freedman, S. J.; Fujikawa, B. K.; Galloway, M.; Gray, F.; Heeger, K. M.; Hsu, L.; Ichimura, K.; Kadel, R.; Keefer, G.; Lendvai, C.; McKee, D.; O' Donnell, T.; Piepke, A.; Steiner, H. M.; Syversrud, D.; Wallig, J.; Winslow, L. A.; Ebihara, T.; Enomoto, S.; Furuno, K.; Gando, Y.; Ikeda, H.; Inoue, K.; Kibe, Y.; Kishimoto, Y.; Koga, M.; Minekawa, Y.; Mitsui, T.; Nakajima, K.; Nakajima, K.; Nakamura, K.; Owada, K.; Shimizu, I.; Shimizu, Y.; Shirai, J.; Suekane, F.; Suzuki, A.; Tamae, K.; Yoshida, S.; Kozlov, A.; Murayama, H.; Grant, C.; Leonard, D. S.; Luk, K.-B.; Jillings, C.; Mauger, C.; McKeown, R. D.; Zhang, C.; Lane, C. E.; Maricic, J.; Miletic, T.; Batygov, M.; Learned, J. G.; Matsuno, S.; Pakvasa, S.; Foster, J.; Horton-Smith, G. A.; Tang, A.; Dazeley, S.; Downum, K. E.; Gratta, G.; Tolich, K.; Bugg, W.; Efremenko, Y.; Kamyshkov, Y.; Perevozchikov, O.; Karwowski, H. J.; Markoff, D. M.; Tornow, W.; Piquemal, F.; Ricol, J.-S.

    2009-03-05

    We have successfully built and operated a source deployment system for the KamLAND detector. This system was used to position radioactive sources throughout the delicate 1-kton liquid scintillator volume, while meeting stringent material cleanliness, material compatibility, and safety requirements. The calibration data obtained with this device were used to fully characterize detector position and energy reconstruction biases. As a result, the uncertainty in the size of the detector fiducial volume was reduced by a factor of two. Prior to calibration with this system, the fiducial volume was the largest source of systematic uncertainty in measuring the number of antineutrinos detected by KamLAND. This paper describes the design, operation and performance of this unique calibration system.

  1. Beyond Low Rank: A Data-Adaptive Tensor Completion Method

    OpenAIRE

    Zhang, Lei; Wei, Wei; Shi, Qinfeng; Shen, Chunhua; Hengel, Anton van den; Zhang, Yanning

    2017-01-01

    Low rank tensor representation underpins much of recent progress in tensor completion. In real applications, however, this approach is confronted with two challenging problems, namely (1) tensor rank determination; (2) handling real tensor data which only approximately fulfils the low-rank requirement. To address these two issues, we develop a data-adaptive tensor completion model which explicitly represents both the low-rank and non-low-rank structures in a latent tensor. Representing the no...

  2. Access to 4-Year Public Colleges and Degree Completion

    OpenAIRE

    Goodman, Joshua Samuel; Hurwitz, Michael; Smith, Jonathan

    2017-01-01

    Does access to 4-year colleges affect degree completion for students who would otherwise attend 2-year colleges? Admission to Georgia’s 4-year public sector requires minimum SAT scores. Regression discontinuity estimates show that access to this sector increases 4-year college enrollment and college quality, largely by diverting students from 2-year colleges. Access substantially increases bachelor’s degree completion rates for these relatively low-skilled students. SAT retaking behavior sugg...

  3. Formal Verification of Real-Time System Requirements

    Directory of Open Access Journals (Sweden)

    Marcin Szpyrka

    2000-01-01

    Full Text Available The methodology of system requirements verification presented in this paper is a proposition of a practical procedure for reducing some negatives of the specification of requirements. The main problem that is considered is to create a complete description of the system requirements without any negatives. Verification of the initially defined requirements is based on the coloured Petri nets. Those nets are useful for testing some properties of system requirements such as completeness, consistency and optimality. An example ofthe litt controller is presented.

  4. ICPP calcined solids storage facility closure study. Volume III: Engineering design files

    International Nuclear Information System (INIS)

    1998-02-01

    The following information was calculated to support cost estimates and radiation exposure calculations for closure activities at the Calcined Solids Storage Facility (CSSF). Within the estimate, volumes were calculated to determine the required amount of grout to be used during closure activities. The remaining calcine on the bin walls, supports, piping, and floor was also calculated to approximate the remaining residual calcine volumes at different stages of the removal process. The estimates for remaining calcine and vault void volume are higher than what would actually be experienced in the field, but are necessary for bounding purposes. The residual calcine in the bins may be higher than was is experienced in the field as it was assumed that the entire bin volume is full of calcine before removal activities commence. The vault void volumes are higher as the vault roof beam volumes were neglected. The estimations that follow should be considered rough order of magnitude, due to the time constraints as dictated by the project's scope of work. Should more accurate numbers be required, a new analysis would be necessary

  5. ICPP calcined solids storage facility closure study. Volume III: Engineering design files

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-02-01

    The following information was calculated to support cost estimates and radiation exposure calculations for closure activities at the Calcined Solids Storage Facility (CSSF). Within the estimate, volumes were calculated to determine the required amount of grout to be used during closure activities. The remaining calcine on the bin walls, supports, piping, and floor was also calculated to approximate the remaining residual calcine volumes at different stages of the removal process. The estimates for remaining calcine and vault void volume are higher than what would actually be experienced in the field, but are necessary for bounding purposes. The residual calcine in the bins may be higher than was is experienced in the field as it was assumed that the entire bin volume is full of calcine before removal activities commence. The vault void volumes are higher as the vault roof beam volumes were neglected. The estimations that follow should be considered rough order of magnitude, due to the time constraints as dictated by the project`s scope of work. Should more accurate numbers be required, a new analysis would be necessary.

  6. Stormwater Volume Control to Prevent Increases in Lake Flooding and Dam Failure Risk

    Science.gov (United States)

    Potter, K. W.

    2017-12-01

    Urban expansion is not often considered a major factor contributing to dam failure. But if urbanization occurs without mitigation of the hydrologic impacts, the risk of dam failure will increase. Of particular concern are increases in the volume of storm runoff resulting from increases in the extent of impervious surfaces. Storm runoff volumes are not regulated for much the U.S, and where they are, the required control is commonly less than 100%. Unmitigated increases in runoff volume due to urbanization can pose a risk to dams. A recent technical advisory committee of Dane County has recommended that the county require 100% control of stormwater volumes for new developments. The primary motivation was to prevent increases in the water levels in the Yahara Lakes, slowly draining lakes that are highly sensitive to runoff volume. The recommendations included the use of "volume trading" to achieve efficient compliance. Such recommendations should be considered for other slowly draining lakes, including those created by artificial structures.

  7. Tank Farms Technical Safety Requirements. Volume 1 and 2

    International Nuclear Information System (INIS)

    CASH, R.J.

    2000-01-01

    The Technical Safety Requirements (TSRs) define the acceptable conditions, safe boundaries, basis thereof, and controls to ensure safe operation during authorized activities, for facilities within the scope of the Tank Waste Remediation System (TWRS) Final Safety Analysis Report (FSAR)

  8. M10.3.4: CLIC crab cavity specifications completed

    CERN Document Server

    Dexter, A; Ambattu, P; Shinton, I; Jones, R

    2010-01-01

    The starting point of Sub-task 2 is to document the currently anticipated requirements for the CLIC crab cavity system. This milestone concerns completion of the basic specifications for the CLIC crab cavity system. This comprises kick, power requirement, phase and amplitude stability, technology choice, and RF layout. The wakefield calculations of a baseline CLIC cavity will be used to estimate the required damping of the higher order modes as well as other special modes in crab cavities (the lower and same order modes).

  9. Waste volume reduction by spray drying

    Energy Technology Data Exchange (ETDEWEB)

    Toscano, Rodrigo A.; Tello, Clédola C. O. de, E-mail: Rodrigotoscano1@gmail.com, E-mail: tellocc@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2017-07-01

    The operation of nuclear facilities generates liquid wastes which require treatment to control the chemical compounds and removal of radioactive contaminants. These wastes can come from the cooling of the primary reactor system, from the reactor pool decontamination, washing of contaminated clothing, among others. The ion exchange resin constitutes the largest fraction of this waste, classified as low and intermediate level of radiation. According to CNEN Standard 8.01, the minimization of the volume and activity of the radioactive waste generated in the operation of a nuclear installation, radiative installation, industrial mining installation or radioactive waste deposit should be ensured. In addition, one of the acceptance criteria for wastes in repositories required by CNEN NN 6.09 is that it be solid or solidified. Thus, these wastes must be reduced in volume and solidified to meet the standards and the safety of the population and the environment. The objective of this work is to find a solution that associates the least generation of packaged waste and the acceptance criteria of waste for the deposition in the national repository. This work presents a proposal of reduction of the volume of the liquid wastes generated by nuclear facilities by drying by for reduction of volume for a greater incorporation of wastes in cement. Using spray dryer, an 18% reduction in the production of cemented waste products was observed in relation to the method currently used with compressive strength measurement above the standard, and it is believed that this value may increase in future tests. (author)

  10. Waste volume reduction by spray drying

    International Nuclear Information System (INIS)

    Toscano, Rodrigo A.; Tello, Clédola C. O. de

    2017-01-01

    The operation of nuclear facilities generates liquid wastes which require treatment to control the chemical compounds and removal of radioactive contaminants. These wastes can come from the cooling of the primary reactor system, from the reactor pool decontamination, washing of contaminated clothing, among others. The ion exchange resin constitutes the largest fraction of this waste, classified as low and intermediate level of radiation. According to CNEN Standard 8.01, the minimization of the volume and activity of the radioactive waste generated in the operation of a nuclear installation, radiative installation, industrial mining installation or radioactive waste deposit should be ensured. In addition, one of the acceptance criteria for wastes in repositories required by CNEN NN 6.09 is that it be solid or solidified. Thus, these wastes must be reduced in volume and solidified to meet the standards and the safety of the population and the environment. The objective of this work is to find a solution that associates the least generation of packaged waste and the acceptance criteria of waste for the deposition in the national repository. This work presents a proposal of reduction of the volume of the liquid wastes generated by nuclear facilities by drying by for reduction of volume for a greater incorporation of wastes in cement. Using spray dryer, an 18% reduction in the production of cemented waste products was observed in relation to the method currently used with compressive strength measurement above the standard, and it is believed that this value may increase in future tests. (author)

  11. Aerojet Energy Conversion Company mobile volume reduction system

    International Nuclear Information System (INIS)

    Smith, K.R.

    1984-01-01

    Over the past few years, rapidly increasing costs for the disposal of low level radioactive waste (LLW) have generated the need for utilities to volume-reduce their LLW prior to shipment and burial. Incineration systems have been selected by several utilities to fulfill this need for maximum volume reduction. Until recently, all of the incineration systems selected by utilities were designed to be housed and operated in a facility erected by the utility. Now, however, lack of capital and rising design/erection costs are causing utilities to reevaluate their plans for purchasing incineration systems to process their LLW. The result is a growing demand for incineration services. Once again, Commonwealth Edison Company (Com-Ed) is leading the industry with an ongoing program to utilize incineration services provided by Aerojet Energy Conversion Company (AECC) for the Dresden Quad Cities, LaSalle, and Zion Nuclear Stations. At the stations, combustible dry active waste and contaminated oil will be processed in a Mobile Volume Reduction System (MVRS) designed and fabricated by AECC. The MVRS is a totally self-contained system consisting of a controlled-air incinerator and a liquid offgas cleanup system. No buildings are required to house the system, and the MVRS achieves volume reduction factors similar to systems currently available for permanent in-plant installation. The result is an option for the utility having the benefits of volume reduction without the capital commitment normally required by the utility

  12. 13 CFR 305.14 - Occupancy prior to completion.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Occupancy prior to completion. 305.14 Section 305.14 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF... the Recipient's risk and must follow the requirements of local and State law. ...

  13. Steckel spaces of electrovacuum with isotropic complete sets

    International Nuclear Information System (INIS)

    Bagrov, V.G.; Evseevich, A.A.; Obukhov, V.V.; Osetrin, K.E.

    1987-01-01

    The system of the Einstein-Maxwell equations for the metrics, generalizing the metrics of space with a complete set of (1.1) type, which is required for classification of the corresponding Steckel spaces of electrovacuum, is integrated. Algebraic classification of the solutions obtained is made

  14. Complete unconscious control: Using (in)action primes to demonstrate completely unconscious activation of inhibitory control mechanisms

    Science.gov (United States)

    Hepler, Justin; Albarracin, Dolores

    2018-01-01

    Although robust evidence indicates that action initiation can occur unconsciously and unintentionally, the literature on action inhibition suggests that inhibition requires both conscious thought and intentionality. In prior research demonstrating automatic inhibition in response to unconsciously processed stimuli, the unconscious stimuli had previously been consciously associated with an inhibitory response within the context of the experiment, and participants had consciously formed a goal to activate inhibition processes when presented with the stimuli (because task instructions required participants to engage in inhibition when the stimuli occurred). Therefore, prior work suggests that some amount of conscious thought and intentionality are required for inhibitory control. In the present research, we recorded event-related potentials during two go/no-go experiments in which participants were subliminally primed with general action/inaction concepts that had never been consciously associated with task-specific responses. We provide the first demonstration that inhibitory control processes can be modulated completely unconsciously and unintentionally. PMID:23747649

  15. 40 CFR 80.92 - Baseline auditor requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Baseline auditor requirements. 80.92... (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Anti-Dumping § 80.92 Baseline auditor requirements. (a... determination methodology, resulting baseline fuel parameter, volume and emissions values verified by an auditor...

  16. Space Tug avionics definition study. Volume 2: Avionics functional requirements

    Science.gov (United States)

    1975-01-01

    Flight and ground operational phases of the tug/shuttle system are analyzed to determine the general avionics support functions that are needed during each of the mission phases and sub-phases. Each of these general support functions is then expanded into specific avionics system requirements, which are then allocated to the appropriate avionics subsystems. This process is then repeated at the next lower level of detail where these subsystem requirements are allocated to each of the major components that comprise a subsystem.

  17. 46 CFR 118.400 - Where required.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Where required. 118.400 Section 118.400 Shipping COAST... Extinguishing and Detecting Systems § 118.400 Where required. (a) The following spaces must be equipped with a... unoccupied space with a gross volume of not more than 170 cubic meters (6,000 cubic feet); (2) A pre...

  18. Completely continuous and weakly completely continuous abstract ...

    Indian Academy of Sciences (India)

    An algebra A is called right completely continuous (right weakly completely continuous) ... Moreover, some applications of these results in group algebras are .... A linear subspace S(G) of L1(G) is said to be a Segal algebra, if it satisfies the.

  19. Supplier Portfolio Selection and Optimum Volume Allocation: A Knowledge Based Method

    NARCIS (Netherlands)

    Aziz, Romana; Aziz, R.; van Hillegersberg, Jos; Kersten, W.; Blecker, T.; Luthje, C.

    2010-01-01

    Selection of suppliers and allocation of optimum volumes to suppliers is a strategic business decision. This paper presents a decision support method for supplier selection and the optimal allocation of volumes in a supplier portfolio. The requirements for the method were gathered during a case

  20. Automatic definition of targeted biological volumes for the radiotherapy applications; Definition automatique des volumes biologiques cibles pour les applications de radiotherapie

    Energy Technology Data Exchange (ETDEWEB)

    Hatt, M.; Visvikis, D. [LaTIM, U650 Inserm, 29 - Brest (France); Cheze-Le-Rest, C. [Service de medecine nucleaire, 29 - Brest (France); Pradier, O. [Service de radiotherapie, 29 - Brest (France)

    2009-10-15

    The proposed method: Fuzzy locally adaptive Bayesian (F.L.A.B.) showed its reliability and its precision on very complete collection of realistic simulated and real data. Its use in the context of radiotherapy allows to consider easily the studies implementation and scenari of dose painting or dose escalation, including in complex cases of heterogenous fixations. It is conceivable to apply F.L.A.B. on PET images with F.M.I.S.O. ({sup 18}F fluoro misonidazole) or F.L.T. (fluoro-L-thymidine) to complete the definition of the biological target volume. (N.C.)

  1. The order and volume fill rates in inventory control systems

    DEFF Research Database (Denmark)

    Thorstenson, Anders; Larsen, Christian

    2011-01-01

    This paper differentiates between an order (line) fill rate and a volume fill rate and specifies their performance for different inventory control systems. When the focus is on filling complete customer orders rather than total quantities the order fill rate would be the preferred service level...... measure. The main result shows how the order and volume fill rates are related in magnitude. Earlier results derived for a single-item, single-stage, continuous review inventory system with backordering and constant lead times controlled by a base-stock policy are extended in different directions...

  2. Volume reduction through incineration of low-activity radioactive wastes

    International Nuclear Information System (INIS)

    Eymeri, J.; Gauthey, J.C.; Chaise, D.; Lafite, G.

    1993-01-01

    The aim of the waste treatment plant, designed by Technicatome (CEA) for an Indonesian Nuclear Research Center, is to reduce through incineration the volume of low-activity radioactive wastes such as technological solids (cotton, PVC, paper board), biological solids (animal bones) and liquids (cutting fluids...). The complete combustion is realized with a total air multi-fuel burner (liquid wastes) and flash pyrolysis-complete combustion (solid wastes). A two stage flue gas filtration system, a flue gas washing system, and an ash recovery system are used. A test platform has been built. 3 figs

  3. Site Environmental Report for 2002, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Pauer, Ron

    2003-07-01

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1. The ''Site Environmental Report for 2002'' summarizes Berkeley Lab's compliance with environmental standards and requirements, characterizes environmental management efforts through surveillance and monitoring activities, and highlights significant programs and efforts for calendar year 2002. Throughout this report, Ernest Orlando Lawrence Berkeley National Laboratory is referred to as ''Berkeley Lab,'' ''the Laboratory,'' ''Lawrence Berkeley National Laboratory,'' and ''LBNL.'' The report is separated into two volumes. Volume I contains a general overview of the Laboratory, the status of environmental programs, and summarized results from surveillance and monitoring activities. Volume II contains individual data results from the monitoring programs. This year, the ''Site Environmental Report'' was distributed on a CD in PDF format that includes Volume I, Volume II, and related documents. The report is also available on the Web at http://www.lbl.gov/ehs/esg/. The report follows the Laboratory's policy of using the International System of Units (SI), also known as the metric system of measurements. Whenever possible, results are additionally reported using the more conventional (non-SI) system of measurements because this system is referenced by some current regulatory standards and is more familiar to some readers. The tables included at the end of the Glossary are intended to help readers understand the various prefixes used with SI units of measurement and convert these units from one system to the other.

  4. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed

    DEFF Research Database (Denmark)

    Posthuma, Daniëlle; Baare, Wim F.C.; Hulshoff Pol, Hilleke E.

    2003-01-01

    We recently showed that the correlation of gray and white matter volume with full scale IQ and the Working Memory dimension are completely mediated by common genetic factors (Posthuma et al., 2002). Here we examine whether the other WAIS III dimensions (Verbal Comprehension, Perceptual Organization......, Processing Speed) are also related to gray and white matter volume, and whether any of the dimensions are related to cerebellar volume. Two overlapping samples provided 135 subjects from 60 extended twin families for whom both MRI scans and WAIS III data were available. All three brain volumes are related...... to Working Memory capacity (r = 0.27). This phenotypic correlation is completely due to a common underlying genetic factor. Processing Speed was genetically related to white matter volume (r(g) = 0.39). Perceptual Organization was both genetically (r(g) = 0.39) and environmentally (r(e) = -0.71) related...

  5. Activation volume of martensitic ODS steel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, D. W.; Noh, S.; Kim, T. K. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Apparent activation volume as a function of temperature is 86b{sup 3}-42b{sup 3}. Activation volume decreases with increasing temperature. Activation volume changes scarcely with decreasing strain rate. Strain rate sensitivity increases with increasing temperature and decreasing strain rate. Nano-sized oxide dispersion strengthened (ODS) martensitic steel has a high strength, low thermal expansion coefficient, high thermal conductivity, and a good swelling resistance. Martensitic ODS steel is a candidate material for fuel cladding of sodium cooled fast breeder reactor (SFR). The plastic flow stress is determined through the interaction of dislocations with the obstacles encountered inside lattice. Dislocation movement through the lattice or past an obstacle requires surmounting of the energy barrier by a combination of applied stress and thermal activation. The plastic deformation of materials is a thermally activated process dependent upon time, temperature, and strain rate. Characterization of the rate controlling mechanism for plastic deformation due to dislocation motion in crystalline materials is done by the assessment of activation volume based on thermal activation analysis.

  6. A complete audit cycle to assess adherence to a lung protective ventilation strategy.

    Science.gov (United States)

    Joynes, Emma; Dalay, Satinder; Patel, Jaimin M; Fayek, Samia

    2014-11-01

    There is clear evidence for the use of a protective ventilation protocol in patients with acute respiratory distress syndrome (ARDS). There is evidence to suggest that protective ventilation is beneficial in patients at risk of ARDS. A protective ventilation strategy was implemented on our intensive care unit in critical care patients who required mechanical ventilation for over 48 h, with and at risk for ARDS. A complete audit cycle was performed over 13 months to assess compliance with a safe ventilation protocol in intensive care. The ARDS network mechanical ventilation protocol was used as the standard for our protective ventilation strategy. This recommends ventilation with a tidal volume (V t) of 6 ml/kg of ideal body weight (IBW) and plateau airway pressure of ≤30 cm H2O. The initial audit failed to meet this standard with V t's of 9.5 ml/kg of IBW. Following the implementation of a ventilation strategy and an educational program, we demonstrate a significant improvement in practice with V t's of 6.6 ml/kg of IBW in the re-audit. This highlights the importance of simple interventions and continuous education in maintaining high standards of care.

  7. Perfection Of Methods Of Mathematical Analysis For Increasing The Completeness Of Subsoil Development

    Science.gov (United States)

    Fokina, Mariya

    2017-11-01

    The economy of Russia is based around the mineral-raw material complex to the highest degree. The mining industry is a prioritized and important area. Given the high competitiveness of businesses in this sector, increasing the efficiency of completed work and manufactured products will become a central issue. Improvement of planning and management in this sector should be based on multivariant study and the optimization of planning decisions, the appraisal of their immediate and long-term results, taking the dynamic of economic development into account. All of this requires the use of economic mathematic models and methodsApplying an economic-mathematic model to determine optimal ore mine production capacity, we receive a figure of 4,712,000 tons. The production capacity of the Uchalinsky ore mine is 1560 thousand tons, and the Uzelginsky ore mine - 3650 thousand. Conducting a corresponding analysis of the production of OAO "Uchalinsky Gok", an optimal production plan was received: the optimal production of copper - 77961,4 rubles; the optimal production of zinc - 17975.66 rubles. The residual production volume of the two main ore mines of OAO "UGOK" is 160 million tons of ore.

  8. A status report on artificial lift systems and challenges in North Dakota horizontal completions

    Energy Technology Data Exchange (ETDEWEB)

    Fangmeier, K. [Amerada Hess Corp., ND (United States)

    2005-07-01

    Partially pressure depleted reservoirs and unfavorable horizontal flow geometries can impact artificial lift designs and diagnostics. In addition, terrain slugging, drilling fines, high gas volume fractions, H{sub 2}S gas and high bottom hole temperatures also pose challenges. This paper provides an overview of various systems utilized by Amerada Hess, a company which examines methods of reducing gas lift gas volumes to achieve maximum flow. A description of naturally fractured reservoirs and limited natural fractures was provided. A comparison was presented between the original conditions at Beaver Lodge Madison and existing conditions with horizontal development. Various artificial lift challenges were examined. It was suggested that high volume lift utilizing gas lift was the preferred artificial lift system for high volume wells. It was noted that downhole sensors can be used as an indicator of potential run life. However, reliability is limited by downhole operating temperatures and electrical ground faults. A comparison of friendly and unfriendly flow systems was presented, as well as a gas lift pressure chart. A summary of average gas volume systems was provided as well as an example of a response to increase drawdown. Examples of downhole Electric Submersible Pump (ESP) sensors were provided, as well as possible flowing pressure profiles in horizontal completion because of the constraints of lift capacity. It was concluded that a single point injection and proven gas lift system is the next step in high volume lift strategy. 2 tabs, 16 figs.

  9. Change in brain and lesion volumes after CEE therapies

    Science.gov (United States)

    Espeland, Mark A.; Hogan, Patricia E.; Resnick, Susan M.; Bryan, R. Nick; Robinson, Jennifer G.; Goveas, Joseph S.; Davatzikos, Christos; Kuller, Lewis H.; Williamson, Jeff D.; Bushnell, Cheryl D.; Shumaker, Sally A.

    2014-01-01

    Objectives: To determine whether smaller brain volumes in older women who had completed Women's Health Initiative (WHI)-assigned conjugated equine estrogen–based hormone therapy (HT), reported by WHI Memory Study (WHIMS)-MRI, correspond to a continuing increased rate of atrophy an average of 6.1 to 7.7 years later in WHIMS-MRI2. Methods: A total of 1,230 WHI participants were contacted: 797 (64.8%) consented, and 729 (59%) were rescanned an average of 4.7 years after the initial MRI scan. Mean annual rates of change in total brain volume, the primary outcome, and rates of change in ischemic lesion volumes, the secondary outcome, were compared between treatment groups using mixed-effect models with adjustment for trial, clinical site, age, intracranial volumes, and time between MRI measures. Results: Total brain volume decreased an average of 3.22 cm3/y in the active arm and 3.07 cm3/y in the placebo arm (p = 0.53). Total ischemic lesion volumes increased in both arms at a rate of 0.12 cm3/y (p = 0.88). Conclusions: Conjugated equine estrogen–based postmenopausal HT, previously assigned at WHI baseline, did not affect rates of decline in brain volumes or increases in brain lesion volumes during the 4.7 years between the initial and follow-up WHIMS-MRI studies. Smaller frontal lobe volumes were observed as persistent group differences among women assigned to active HT compared with placebo. Women with a history of cardiovascular disease treated with active HT, compared with placebo, had higher rates of accumulation in white matter lesion volume and total brain lesion volume. Further study may elucidate mechanisms that explain these findings. PMID:24384646

  10. Information base for waste repository design. Volume 5. Decommissioning of underground facilities. Technical report

    International Nuclear Information System (INIS)

    Giuffre, M.S.; Plum, R.L.; Koplik, C.M.; Talbot, R.

    1979-03-01

    This report is Volume 5 of a seven volume document on nuclear waste repository design issues. This report discusses the requirements for decommissioning a deep underground facility for the disposal of radioactive waste. The techniques for sealing the mined excavations are presented and an information base on potential backfill materials is provided. Possible requirements for monitoring the site are discussed. The performance requirements for backfill materials are outlined. The advantages and disadvantages of each sealing method are stated

  11. Scan-based volume animation driven by locally adaptive articulated registrations.

    Science.gov (United States)

    Rhee, Taehyun; Lewis, J P; Neumann, Ulrich; Nayak, Krishna S

    2011-03-01

    This paper describes a complete system to create anatomically accurate example-based volume deformation and animation of articulated body regions, starting from multiple in vivo volume scans of a specific individual. In order to solve the correspondence problem across volume scans, a template volume is registered to each sample. The wide range of pose variations is first approximated by volume blend deformation (VBD), providing proper initialization of the articulated subject in different poses. A novel registration method is presented to efficiently reduce the computation cost while avoiding strong local minima inherent in complex articulated body volume registration. The algorithm highly constrains the degrees of freedom and search space involved in the nonlinear optimization, using hierarchical volume structures and locally constrained deformation based on the biharmonic clamped spline. Our registration step establishes a correspondence across scans, allowing a data-driven deformation approach in the volume domain. The results provide an occlusion-free person-specific 3D human body model, asymptotically accurate inner tissue deformations, and realistic volume animation of articulated movements driven by standard joint control estimated from the actual skeleton. Our approach also addresses the practical issues arising in using scans from living subjects. The robustness of our algorithms is tested by their applications on the hand, probably the most complex articulated region in the body, and the knee, a frequent subject area for medical imaging due to injuries. © 2011 IEEE

  12. Radioiodine therapy of functional autonomy using the functional autonomous volume

    International Nuclear Information System (INIS)

    Seeger, T.; Emrich, D.; Sandrock, D.

    1995-01-01

    In order to determine the effective radiation dose to be delivered by 131 I in functional autonomy we have used the functional autonomous volume calculated from the global 99m Tc thyroid uptake under exogenous or endogenous suppression before and 3 to 7 months after treatment. The radiation dose to the autonomous volume was calculated retrospectively in 131 patients with unifocal, multifocal and disseminated autonomy (75 hyperthyroid, 56 euthyroid) who received 131 I treatment of 200-300 Gy to the total volume of the gland. It could be shown that at least 350 Gy to the autonomous volume are required to reach the desired effect of treatment which was dependent only on the radiation dose delivered to the functional autonomous volume. (orig.) [de

  13. Volume of hydration in terminal cancer patients.

    Science.gov (United States)

    Bruera, E; Belzile, M; Watanabe, S; Fainsinger, R L

    1996-03-01

    In this retrospective study we reviewed the volume and modality of hydration of consecutive series of terminal cancer patients in two different settings. In a palliative care unit 203/290 admitted patients received subcutaneous hydration for 12 +/- 8 days at a daily volume of 1015 +/- 135 ml/day. At the cancer center, 30 consecutive similar patients received intravenous hydration for 11.5 +/- 5 days (P > 0.2) but at a daily volume of 2080 +/- 720 ml/day (P palliative care unit patients required discontinuation of hydration because of complications. Hypodermoclysis was administered mainly as a continuous infusion, an overnight infusion, or in one to three 1-h boluses in 62 (31%), 98 (48%) and 43 (21%) patients, respectively. Our findings suggest that, in some settings, patients may be receiving excessive volumes of hydration by less comfortable routes such as the intravenous route. Increased education and research in this area are badly needed.

  14. The order and volume fill rates in inventory control systems

    DEFF Research Database (Denmark)

    Thorstenson, Anders; Larsen, Christian

    2011-01-01

    This paper differentiates between an order (line) fill rate and a volume fill rate and specifies their performance for different inventory control systems. When the focus is on filling complete customer orders rather than total quantities the order fill rate would be the preferred service level m...

  15. Comparison of Statistically Modeled Contaminated Soil Volume Estimates and Actual Excavation Volumes at the Maywood FUSRAP Site - 13555

    Energy Technology Data Exchange (ETDEWEB)

    Moore, James [U.S. Army Corps of Engineers - New York District 26 Federal Plaza, New York, New York 10278 (United States); Hays, David [U.S. Army Corps of Engineers - Kansas City District 601 E. 12th Street, Kansas City, Missouri 64106 (United States); Quinn, John; Johnson, Robert; Durham, Lisa [Argonne National Laboratory, Environmental Science Division 9700 S. Cass Ave., Argonne, Illinois 60439 (United States)

    2013-07-01

    As part of the ongoing remediation process at the Maywood Formerly Utilized Sites Remedial Action Program (FUSRAP) properties, Argonne National Laboratory (Argonne) assisted the U.S. Army Corps of Engineers (USACE) New York District by providing contaminated soil volume estimates for the main site area, much of which is fully or partially remediated. As part of the volume estimation process, an initial conceptual site model (ICSM) was prepared for the entire site that captured existing information (with the exception of soil sampling results) pertinent to the possible location of surface and subsurface contamination above cleanup requirements. This ICSM was based on historical anecdotal information, aerial photographs, and the logs from several hundred soil cores that identified the depth of fill material and the depth to bedrock under the site. Specialized geostatistical software developed by Argonne was used to update the ICSM with historical sampling results and down-hole gamma survey information for hundreds of soil core locations. The updating process yielded both a best guess estimate of contamination volumes and a conservative upper bound on the volume estimate that reflected the estimate's uncertainty. Comparison of model results to actual removed soil volumes was conducted on a parcel-by-parcel basis. Where sampling data density was adequate, the actual volume matched the model's average or best guess results. Where contamination was un-characterized and unknown to the model, the actual volume exceeded the model's conservative estimate. Factors affecting volume estimation were identified to assist in planning further excavations. (authors)

  16. High Volume Manufacturing and Field Stability of MEMS Products

    Science.gov (United States)

    Martin, Jack

    Low volume MEMS/NEMS production is practical when an attractive concept is implemented with business, manufacturing, packaging, and test support. Moving beyond this to high volume production adds requirements on design, process control, quality, product stability, market size, market maturity, capital investment, and business systems. In a broad sense, this chapter uses a case study approach: It describes and compares the silicon-based MEMS accelerometers, pressure sensors, image projection systems, and gyroscopes that are in high volume production. Although they serve several markets, these businesses have common characteristics. For example, the manufacturing lines use automated semiconductor equipment and standard material sets to make consistent products in large quantities. Standard, well controlled processes are sometimes modified for a MEMS product. However, novel processes that cannot run with standard equipment and material sets are avoided when possible. This reliance on semiconductor tools, as well as the organizational practices required to manufacture clean, particle-free products partially explains why the MEMS market leaders are integrated circuit manufacturers. There are other factors. MEMS and NEMS are enabling technologies, so it can take several years for high volume applications to develop. Indeed, market size is usually a strong function of price. This becomes a vicious circle, because low price requires low cost - a result that is normally achieved only after a product is in high volume production. During the early years, IC companies reduced cost and financial risk by using existing facilities for low volume MEMS production. As a result, product architectures are partially determined by capabilities developed for previous products. This chapter includes a discussion of MEMS product architecture with particular attention to the impact of electronic integration, packaging, and surfaces. Packaging and testing are critical, because they are

  17. Maximizing productivity of horizontal drilling and completion techniques

    Energy Technology Data Exchange (ETDEWEB)

    Schein, G. [BJ Services Company, Calgary, AB (Canada)

    2007-07-01

    There are currently 160 active drilling rigs in the Barnett shale play, and small early developments have now become large-scale operations. This presentation outlined methods currently used to improve the productivity of directional drilling and completion techniques in gas shale plays. Horizontal completions are used to control height growth and increase contact areas. A typical horizontal well casing program was described along with details of cement liner treatment programs. Charts of optimum and non-optimum azimuth wells were included. Increased reservoir contact has been achieved by using limited-entry designs and acid stages with ball-sealers and abrasive jet-cutters. Pump rates have been increased during various stages, and larger fluid and sand volumes were used. A mineralogy comparison was provided, as well as details of the general design criteria for vertical wells in the region. It was concluded that drilling in the Barnett shale play has been successful as a result of using 3-dimensional seismic mapping as well as by initiating multiple, simultaneous fracs. The presentation also included charts of the Arkoma-Woodford play, the Arkoma-Fayetteville play, and the Delaware Basin. tabs., figs.

  18. SPORT AND EXERCISE PHYSIOLOGY TESTING Volume one: Sport Testing Volume two: Exercise and Clinical Testing

    Directory of Open Access Journals (Sweden)

    Edward M. Winter

    2007-03-01

    Full Text Available DESCRIPTION The objective of the book is to discuss the theoretical and practical aspects of physiological testing in exercise and sports which is essential to evaluate and monitor developing exercise performance for athletes and public health, and improving quality of life for patients.A board of leading sport and exercise physiologists and scientists are gathered to discuss physiological assessments that have proven validity and reliability, both in sport and health relevant issues. Incidentally, it updates the reader about the current subjects of physiological exertion testing in both research and clinical procedures. Both volumes individually cover the increasing number of available research and review publications, and theoretical explanations are supported by practical examples. A step-by-step and/or checklist method is used in appropriate sections which make the guides more user-friendly than most. PURPOSE The first volume is designed to help readers develop an understanding of the essential concepts of sport specific testing whereas the second volume aims at making the exercise and clinical specific testing comprehensible, dealing with both technical terms and the theories underlying the importance of these tests. AUDIENCE As Guidelines books of the British Association of Sport and Exercise Sciences, it will be of interest to a wide range of students, researchers and practitioners in the sport and exercise disciplines whether they work in the laboratory or in the field. FEATURES The first volume features immediate practical requirements particularly in sport testing. It is composed of five parts with detailed sub-sections in all of them. The topics of the parts are: i general principles, ii methodological issues, iii general procedures, iv sport specific procedures, v special populations.The second volume is also presented in five parts, again with sub-sections in all of them, but considering the requirements in clinical and exercise

  19. Mod-5A wind turbine generator program design report. Volume 4: Drawings and specifications, book 2

    Science.gov (United States)

    1984-01-01

    The design, development and analysis of the 7.3 MW MOD-5A wind turbine generator is documented. There are four volumes. This volume contains the drawings and specifications that were developed in preparation for building the MOD-5A wind turbine generator. This is the second book of volume four. Some of the items it contains are specs for the emergency shutdown panel, specs for the simulator software, simulator hardware specs, site operator terminal requirements, control data system requirements, software project management plan, elastomeric teeter bearing requirement specs, specs for the controls electronic cabinet, and specs for bolt pretensioning.

  20. 50 CFR 23.51 - What are the requirements for issuing a partially completed CITES document?

    Science.gov (United States)

    2010-10-01

    ..., BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE... CITES documents only when: (i) The permitted trade will have a negligible impact or no impact on the... completed documents benefits both the permit holder and the issuing Management Authority. (2) The proposed...

  1. A VOLUME-LIMITED PHOTOMETRIC SURVEY OF 114 γ DORADUS CANDIDATES

    International Nuclear Information System (INIS)

    Henry, Gregory W.; Fekel, Francis C.; Henry, Stephen M.

    2011-01-01

    We have carried out a photometric survey of a complete, volume-limited sample of γ Doradus candidates. The sample was extracted from the Hipparcos catalog and consists of 114 stars with colors and absolute magnitudes within the range of known γ Doradus stars and that also lie within a specified volume of 266,600 pc 3 . We devoted one year of observing time with our T12 0.8 m automatic photometric telescope to acquire nightly observations of the complete sample of stars. From these survey observations, we identify 37 stars with intrinsic variability of 0.002 mag or more. Of these 37 variables, 8 have already been confirmed as γ Doradus stars in our earlier papers; we scheduled the remaining 29 variables on our T3 0.4 m automatic telescope to acquire more intensive observations over the next two years. As promising new γ Doradus candidates were identified from the photometry, we obtained complementary spectroscopic observations of each candidate with the Kitt Peak coude feed telescope. Analysis of our new photometric and spectroscopic data reveals 15 new γ Doradus variables (and confirms two others), 8 new δ Scuti variables (and confirms one other), and 3 new variables with unresolved periodicity. Therefore, of the 114 γ Doradus candidates in our volume-limited sample, we find 25 stars that are new or previously known γ Doradus variables. This results in an incidence of 22% for γ Doradus variability among candidate field stars for this volume of the solar neighborhood. The corresponding space density of γ Doradus stars in this volume of space is 0.094 stars per 10 3 pc 3 or 94 stars per 10 6 pc 3 . We provide an updated list of 86 bright, confirmed, γ Doradus field stars.

  2. Three-dimensional transvaginal sonographic assessment of uterine volume as preoperative predictor of need to morcellate in women undergoing laparoscopic hysterectomy.

    Science.gov (United States)

    Gerges, B; Mongelli, M; Casikar, I; Bignardi, T; Condous, G

    2017-08-01

    In light of recent statements from the United States Food and Drug Administration warning against the use of power morcellation of uterine leiomyomas during laparoscopy, we sought to evaluate the use of preoperative two- (2D) and three- (3D) dimensional transvaginal ultrasound (US) assessment of uterine volume to predict the need for morcellation in women undergoing laparoscopic hysterectomy (LH). This was a prospective observational study performed between October 2008 and November 2011 in a tertiary referral laparoscopic unit. All women scheduled to undergo LH were included and underwent detailed preoperative transvaginal US. Uterine volumes were calculated using 2D-US measurements (ellipsoid formula), and using Virtual Organ Computer-aided AnaLysis (VOCAL™) having acquired 3D-US volumes of the uterus. Age, parity, need to morcellate and final uterine dry weight at histology were recorded. The estimated uterine volumes were then incorporated into a previously published logistic regression model to predict the need to morcellate for both nulliparous and parous women. The probability threshold cut-off of 0.14 (95% sensitivity) was evaluated in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and likelihood ratios (LRs). The performance of the models incorporating 2D- and 3D-US calculations were compared with 2D- and 3D-US-generated volumes alone, using receiver-operating characteristics (ROC) curves. Of 76 women who underwent LH during the study period, 79% (n = 60) had complete background and 3D-US data. Their mean age was 43.7 years, 91.7% were parous and 35% underwent morcellation. The greatest uterine volume that did not require morcellation was 404 mL estimated using 3D-US, which corresponded to a uterine volume of 688.8 mL using 2D-US. The smallest uterine volume that required morcellation was 118.9 mL using 3D-US, which corresponded to a uterine volume of 123.4 mL using 2D-US. The 3D-US uterine volume for

  3. Electrocautery versus Stapler for Intersegmental Plane Dissection in Complete 
Thoracoscopic Segmentectomy

    Directory of Open Access Journals (Sweden)

    Haibo LIU

    2017-01-01

    Full Text Available Background and objective Complete thoracoscopic segmentectomy gained great attention with the high detection rate of early lung cancer. Electrocautery and stapler are most commonly used in dividing the intersegmental plane in pulmonary segmentectomy. However, few reports comparing the two methods exist; all of which contrapose an open approach because complete thoracoscopic approach is not mentioned. The aim of this study is to evaluate and compare the safety and efficacy of the two methods in intersegmental plane dissection during complete thoracoscopic pulmonary segmentectomy. Methods A retrospective review of prospectively collected data was obtained for 58 consecutive patients who were treated by segmentectomy between September 2013 and March 2016 at a single center. The patients were divided into two groups according to the methods in intersegmental plane dissection. Thirty patients underwent intersegmental plane dissection with electrocautery (electrocautery group, and 28 patients underwent the same process using staplers (stapler group. Preoperative, intraoperative, and postoperative variables for patients were compared between two groups. Results The operative time of electrocautery group was longer than that of the stapler group [(248.70±54.46 min vs (209.39±67.25 min, P=0.017]. Furthermore, no statistical difference was found between two groups in intraoperative blood loss (60.00 mL vs 65.00 mL, total drainage volume (445.00 mL vs 590.00 mL, drainage volume in first 3 days after surgery [(455.33±318.333 mL vs (422.32±194.95 mL], duration of chest tube drainage [(4.20±2.07 d vs (4.11±1.61 d], postoperative hospital stay [(6.33±2.98 d vs (5.89±1.55 d], and incidence of minor postoperative complication [16.7% (5/30 vs 7.1% (2/28]. Conclusion Although operative time was longer in electrocautery group than in stapler group, using electrocautery for intersegmental plane dissection in complete thoracoscopic segmentectomy appeared to

  4. [Electrocautery versus Stapler for Intersegmental Plane Dissection in Complete 
Thoracoscopic Segmentectomy].

    Science.gov (United States)

    Liu, Haibo; Lin, Gang; Zhang, Shijie; Huang, Weiming; Shang, Xueqian; Li, Jian

    2017-01-20

    Complete thoracoscopic segmentectomy gained great attention with the high detection rate of early lung cancer. Electrocautery and stapler are most commonly used in dividing the intersegmental plane in pulmonary segmentectomy. However, few reports comparing the two methods exist; all of which contrapose an open approach because complete thoracoscopic approach is not mentioned. The aim of this study is to evaluate and compare the safety and efficacy of the two methods in intersegmental plane dissection during complete thoracoscopic pulmonary segmentectomy. A retrospective review of prospectively collected data was obtained for 58 consecutive patients who were treated by segmentectomy between September 2013 and March 2016 at a single center. The patients were divided into two groups according to the methods in intersegmental plane dissection. Thirty patients underwent intersegmental plane dissection with electrocautery (electrocautery group), and 28 patients underwent the same process using staplers (stapler group). Preoperative, intraoperative, and postoperative variables for patients were compared between two groups. The operative time of electrocautery group was longer than that of the stapler group [(248.70±54.46) min vs (209.39±67.25) min, P=0.017]. Furthermore, no statistical difference was found between two groups in intraoperative blood loss (60.00 mL vs 65.00 mL), total drainage volume (445.00 mL vs 590.00 mL), drainage volume in first 3 days after surgery [(455.33±318.333) mL vs (422.32±194.95) mL], duration of chest tube drainage [(4.20±2.07) d vs (4.11±1.61) d], postoperative hospital stay [(6.33±2.98) d vs (5.89±1.55) d], and incidence of minor postoperative complication [16.7% (5/30) vs 7.1% (2/28)]. Although operative time was longer in electrocautery group than in stapler group, using electrocautery for intersegmental plane dissection in complete thoracoscopic segmentectomy appeared to be a very safe and feasible procedure compared with stapler.

  5. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed.

    Science.gov (United States)

    Posthuma, Daniëlle; Baaré, Wim F C; Hulshoff Pol, Hilleke E; Kahn, René S; Boomsma, Dorret I; De Geus, Eco J C

    2003-04-01

    We recently showed that the correlation of gray and white matter volume with full scale IQ and the Working Memory dimension are completely mediated by common genetic factors (Posthuma et al., 2002). Here we examine whether the other WAIS III dimensions (Verbal Comprehension, Perceptual Organization, Processing Speed) are also related to gray and white matter volume, and whether any of the dimensions are related to cerebellar volume. Two overlapping samples provided 135 subjects from 60 extended twin families for whom both MRI scans and WAIS III data were available. All three brain volumes are related to Working Memory capacity (r = 0.27). This phenotypic correlation is completely due to a common underlying genetic factor. Processing Speed was genetically related to white matter volume (r(g) = 0.39). Perceptual Organization was both genetically (r(g) = 0.39) and environmentally (r(e) = -0.71) related to cerebellar volume. Verbal Comprehension was not related to any of the three brain volumes. It is concluded that brain volumes are genetically related to intelligence which suggests that genes that influence brain volume may also be important for intelligence. It is also noted however, that the direction of causation (i.e., do genes influence brain volume which in turn influences intelligence, or alternatively, do genes influence intelligence which in turn influences brain volume), or the presence or absence of pleiotropy has not been resolved yet.

  6. Low-volume plus ascorbic acid vs high-volume plus simethicone bowel preparation before colonoscopy

    Science.gov (United States)

    Pontone, Stefano; Angelini, Rita; Standoli, Monica; Patrizi, Gregorio; Culasso, Franco; Pontone, Paolo; Redler, Adriano

    2011-01-01

    AIM: To investigate the effectiveness of low-volume plus ascorbic acid [polyethylene glycol plus ascorbic acid (PEG + Asc)] and high-volume plus simethicone [polyethylene glycol plus simethicone (PEG + Sim)] bowel preparations. METHODS: A total of one hundred and forty-four outpatients (76 males), aged from 20 to 84 years (median age 59.5 years), who attended our Department, were divided into two groups, age and sex matched, and underwent colonoscopy. Two questionnaires, one for patients reporting acceptability and the other for endoscopists evaluating bowel cleansing effectiveness according to validated scales, were completed. Indications, timing of examination and endoscopical findings were recorded. Biopsy forceps were used as a measuring tool in order to determine polyp endoscopic size estimation. Difficulty in completing the preparation was rated in a 5-point Likert scale (1 = easy to 5 = unable). Adverse experiences (fullness, cramps, nausea, vomiting, abdominal pain, headache and insomnia), number of evacuations and types of activities performed during preparation (walking or resting in bed) were also investigated. RESULTS: Seventy-two patients were selected for each group. The two groups were age and sex matched as well as being comparable in terms of medical history and drug therapies taken. Fourteen patients dropped out from the trial because they did not complete the preparation procedure. Ratings of global bowel cleansing examinations were considered to be adequate in 91% of PEG + Asc and 88% of PEG + Sim patients. Residual Stool Score indicated similar levels of amount and consistency of residual stool; there was a significant difference in the percentage of bowel wall visualization in favour of PEG + Sim patients. In the PEG + Sim group, 12 adenomas ≤ 10 mm diameter (5/left colon + 7/right colon) vs 9 (8/left colon + 1/right colon) in the PEG + Asc group were diagnosed. Visualization of small lesions seems to be one of the primary advantages of the

  7. [Hospitals failing minimum volumes in 2004: reasons and consequences].

    Science.gov (United States)

    Geraedts, M; Kühnen, C; Cruppé, W de; Blum, K; Ohmann, C

    2008-02-01

    In 2004 Germany introduced annual minimum volumes nationwide on five surgical procedures: kidney, liver, stem cell transplantation, complex oesophageal, and pancreatic interventions. Hospitals that fail to reach the minimum volumes are no longer allowed to perform the respective procedures unless they raise one of eight legally accepted exceptions. The goal of our study was to investigate how many hospitals fell short of the minimum volumes in 2004, whether and how this was justified, and whether hospitals that failed the requirements experienced any consequences. We analysed data on meeting the minimum volume requirements in 2004 that all German hospitals were obliged to publish as part of their biannual structured quality reports. We performed telephone interviews: a) with all hospitals not achieving the minimum volumes for complex oesophageal, and pancreatic interventions, and b) with the national umbrella organisations of all German sickness funds. In 2004, one quarter of all German acute care hospitals (N=485) performed 23,128 procedures where minimum volumes applied. 197 hospitals (41%) did not meet at least one of the minimum volumes. These hospitals performed N=715 procedures (3.1%) where the minimum volumes were not met. In 43% of these cases the hospitals raised legally accepted exceptions. In 33% of the cases the hospitals argued using reasons that were not legally acknowledged. 69% of those hospitals that failed to achieve the minimum volumes for complex oesophageal and pancreatic interventions did not experience any consequences from the sickness funds. However, one third of those hospitals reported that the sickness funds addressed the issue and partially announced consequences for the future. The sickness funds' umbrella organisations stated that there were only sparse activities related to the minimum volumes and that neither uniform registrations nor uniform proceedings in case of infringements of the standards had been agreed upon. In spite of the

  8. Assessment of the requirements for DOE's annual report to congress on low-level radioactive waste

    International Nuclear Information System (INIS)

    1987-10-01

    The Low-level Radioactive Waste Policy Amendments Act of 1985 (PL99-240; LLRWPAA) requires the Department of Energy (DOE) to ''submit to Congress on an annual basis a report which: (1) summarizes the progress of low-level waste disposal siting and licensing activities within each compact region, (2) reviews the available volume reduction technologies, their applications, effectiveness, and costs on a per unit volume basis, (3) reviews interim storage facility requirements, costs, and usage, (4) summarizes transportation requirements for such wastes on an inter- and intra-regional basis, (5) summarizes the data on the total amount of low-level waste shipped for disposal on a yearly basis, the proportion of such wastes subjected to volume reduction, the average volume reduction attained,, and the proportion of wastes stored on an interim basis, and (6) projects the interim storage and final disposal volume requirements anticipated for the following year, on a regional basis (Sec. 7(b)).'' This report reviews and assesses what is required for development of the annual report specified in the LLRWPAA. This report addresses each of the subject areas set out in the LLRWPAA

  9. Timely Post-Graduate Degree Completion: A Case Study of Jamshoro Education City

    Directory of Open Access Journals (Sweden)

    Jagul Huma Lashari

    2013-01-01

    Full Text Available This study identifies the status of postgraduate students at the master degree level regarding their degree completion in the three public sector universities at Jamshoro Education City. The status is identified by analyzing enrolment of the postgraduate and comparing it with rate of their degree completion. In addition, the paper also discusses their characteristics which lead them towards the degree completion. For this paper, enrolment of the postgraduate students at the master level is compared with the degree completion rate of 2008 academic session only. The result shows the obvious difference between enrolment and rate of the degree completion. In total 417 postgraduate students were enrolled in 2008 session, however, only 60 (14% of students have completed their postgraduate degrees. Those who have completed their degrees, with respect to universities 6% students belong to US (University of Sindh, 22% belong to MUET (Mehran University of Engineering & Technology and 8% students belong to LUMHS (Liaquat University of Medical & Health Sciences. The demographical data of the postgraduate students has also shown some variations like gender, age, employment, and financial resources. In addition, the research requirements also vary for different postgraduate students. The research requirements include lab based, field based and library based resources. The characteristics of the postgraduate students of three public sector universities including financial resources, employment status, and working organization also show differences with each-other in terms of the degree completion.

  10. Completion of the Temelin nuclear power plant

    International Nuclear Information System (INIS)

    Zavodsky, Petr

    2012-01-01

    The article consists of the following sections: Introduction - current situation in the nuclear sector; (1) Where is Europe heading? (2) What options does the Czech Republic's have available? (3) Nuclear is the best solution; (4) What nuclear projects is CEZ Group preparing? (A - Contractor selection; B - Environmental impact assessment and licensing process; C- Associated investments); (5) Why at Temelin? (6) Safety and legislative requirements; (7) Which technologies? (8) Potential contractors; (8.1) AP1000; (8.2.) EPR; (8.3) MIR1200; (9) Completion of the NPP will contribute to the country's economic growth and competitiveness; (10) Contribution to environmental protection; and (11) The effects of the Temelin plant completion on the environment are assessed with the EIA procedure. (P.A.)

  11. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID)

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 3) presents the standards and requirements for the following sections: Safeguards and Security, Engineering Design, and Maintenance.

  12. High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID)

    International Nuclear Information System (INIS)

    1994-04-01

    The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 3) presents the standards and requirements for the following sections: Safeguards and Security, Engineering Design, and Maintenance

  13. Experiences in certification of packages for transportation of fresh nuclear fuel in the context of new safety requirements established by IAEA regulations (IAEA-96 regulations, ST-1) for air transportation of nuclear materials (requirements to C-type packages)

    Energy Technology Data Exchange (ETDEWEB)

    Dudai, V.I.; Kovtun, A.D.; Matveev, V.Z.; Morenko, A.I.; Nilulin, V.M.; Shapovalov, V.I.; Yakushev, V.A.; Bobrovsky, V.S.; Rozhkov, V.V.; Agapov, A.M.; Kolesnikov, A.S. [Russian Federal Nuclear Centre - All-Russian Research Inst. of Experimental Physics, Sarov (Russian Federation)]|[JSC ' ' MSZ' ' , Electrostal (Russian Federation)]|[JSC ' ' NPCC' ' , Novosibirsk (Russian Federation)]|[Minatom of Russia, Moscow (Russian Federation)]|[Gosatomnadzor of Russia, Moscow (Russian Federation)

    2004-07-01

    Every year in Russia, a large amount of domestic and international transportation of fresh nuclear fuel (FNF) used in Russian and foreign energy and research atomic reactors and referred to fissile materials based on IAEA Regulations is performed. Here, bulk transportation is performed by air, and it concerns international transportation in particular. According to national ''Main Regulations for Safe Transport and physical Protection of Nuclear Materials (OPBZ- 83)'' and ''Regulations for the Safe Transport of Radioactive Materials'' of the International Atomic Energy Agency (IAEA Regulations), nuclear and radiation security under normal (accident free) and accident conditions of transport must be completely provided by the package design. In this context, high requirements to fissile packages exposed to heat and mechanical loads in transport accidents are imposed. A long-standing experience in accident free transportation of FM has shown that such approach to provide nuclear and radiation security pays for itself completely. Nevertheless, once in 10 years the International Atomic Energy Agency on every revision of the ''Regulations for the Safe Transport of Radioactive Materials'' places more stringent requirements upon the FM and transportation thereof, resulting from the objectively increasing risk associated with constant rise in volume and density of transportation, and also strained social and economical situation in a number of regions in the world. In the new edition of the IAEA Regulations (ST-1), published in 1996 and brought into force in 2001 (IAEA-96 Regulations), the requirements to FM packages conveyed by aircraft were radically changed. These requirements are completely presented in new Russian ''Regulations for the Safe Transport of Radioactive Materials'' (PBTRM- 2004) which will be brought into force in the time ahead.

  14. Complete motif analysis of sequence requirements for translation initiation at non-AUG start codons.

    Science.gov (United States)

    Diaz de Arce, Alexander J; Noderer, William L; Wang, Clifford L

    2018-01-25

    The initiation of mRNA translation from start codons other than AUG was previously believed to be rare and of relatively low impact. More recently, evidence has suggested that as much as half of all translation initiation utilizes non-AUG start codons, codons that deviate from AUG by a single base. Furthermore, non-AUG start codons have been shown to be involved in regulation of expression and disease etiology. Yet the ability to gauge expression based on the sequence of a translation initiation site (start codon and its flanking bases) has been limited. Here we have performed a comprehensive analysis of translation initiation sites that utilize non-AUG start codons. By combining genetic-reporter, cell-sorting, and high-throughput sequencing technologies, we have analyzed the expression associated with all possible variants of the -4 to +4 positions of non-AUG translation initiation site motifs. This complete motif analysis revealed that 1) with the right sequence context, certain non-AUG start codons can generate expression comparable to that of AUG start codons, 2) sequence context affects each non-AUG start codon differently, and 3) initiation at non-AUG start codons is highly sensitive to changes in the flanking sequences. Complete motif analysis has the potential to be a key tool for experimental and diagnostic genomics. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  15. The role of completion imaging following carotid artery endarterectomy.

    Science.gov (United States)

    Ricco, Jean-Baptiste; Schneider, Fabrice; Illuminati, Giulio; Samson, Russell H

    2013-05-01

    A variety of completion imaging methods can be used during carotid endarterectomy to recognize technical errors or intrinsic abnormalities such as mural thrombus or platelet aggregation, but none of these methods has achieved wide acceptance, and their ability to improve the outcome of the operation remains a matter of controversy. It is unclear if completion imaging is routinely necessary and which abnormalities require re-exploration. Proponents of routine completion imaging argue that identification of these abnormalities will allow their immediate correction and avoid a perioperative stroke. However, much of the evidence in favor of this argument is incidental, and many experienced vascular surgeons who perform carotid endarterectomy do not use any completion imaging technique and report equally good outcomes using a careful surgical protocol. Furthermore, certain postoperative strokes, including intracerebral hemorrhage and hyperperfusion syndrome, are unrelated to the surgical technique and cannot be prevented by completion imaging. This controversial subject is now open to discussion, and our debaters have been given the task to clarify the evidence to justify their preferred option for completion imaging during carotid endarterectomy. Copyright © 2013 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

  16. Non-functional Avionics Requirements

    Science.gov (United States)

    Paulitsch, Michael; Ruess, Harald; Sorea, Maria

    Embedded systems in aerospace become more and more integrated in order to reduce weight, volume/size, and power of hardware for more fuel-effi ciency. Such integration tendencies change architectural approaches of system ar chi tec tures, which subsequently change non-functional requirements for plat forms. This paper provides some insight into state-of-the-practice of non-func tional requirements for developing ultra-critical embedded systems in the aero space industry, including recent changes and trends. In particular, formal requi re ment capture and formal analysis of non-functional requirements of avionic systems - including hard-real time, fault-tolerance, reliability, and per for mance - are exemplified by means of recent developments in SAL and HiLiTE.

  17. Comparison of six methods of segmentation of tumor volume on the 18F-F.D.G. PET scan with reference histological volume in non small cell bronchopulmonary cancers

    International Nuclear Information System (INIS)

    Venel, Y.; Garhi, H.; Baulieu, J.L.; Prunier-Aesch, C.; Muret, A. de; Barillot, I.

    2008-01-01

    The 18 F-F.D.G. PET has demonstrated its importance in oncology, for initial extension and efficacy of anti tumoral therapeutics. Several studies have attempted to prove its utility to define tumoral volumes for conformational radiotherapy in non small cell lung cancers. Some authors have suggested the use of threshold of tumor intensity uptake with 40 or 50% of maximal intensity. Black et al. have determined contouring with linear regression formula of mean semi-quantitative index of tumor uptake (standard uptake value): SUV threshold = 0.307 Sub average + 0.588. Nestle et al. have taken into account the background noise intensity and mean intensity of the tumor: I threshold = β I average +I noise with β 0.15. Our study was done in collaboration with Inserm U618 team and has compared volumes defined on PET scan defined according to different methods based on intensity or S.U.V. to the tumour volume determined on CT scan by radio physicist. We have compared those volumes with histological volume that we considered for reference. Four patients have been included. They had 18 F-F.D.G. PET scan followed by complete tumoral removal surgery. Specific histological procedure allowed to define complete size of the tumor in re expanded lung. Comparatively to pathology, the volumes obtained using I max 40 and I max 50 are all underestimated. The volumes defined by Black's et al. method are under evaluated for the two largest tumours (15.8% to 22%) and overestimated for the two smallest ones (17.9 to 82.9%). Nestle's et al. method, using β = 0.15, correctly estimates two tumor volumes over 2 cm, but overestimates the two small tumors (79.6 to 124%). Finally, the corrected Nestle's et al. formula (using β = 0.264) overestimates three tumours. Volumes defined on CT scan by radio physicist are correct for one lesion, underestimated for one and overestimated for two other ones (44 and 179.5%). Nestle's et al. method seems to be the most accurate for tumours over 2 cm of

  18. Gravel packing dual zones in one trip reduces offshore completion time

    International Nuclear Information System (INIS)

    Brannon, D.H.; Harrison, D.T.; van Sickle, E.W.

    1991-01-01

    A single trip, dual-zone gravel pack system was used to successfully gravel pack two wells on Green Canyon platform 52 A in the Gulf of Mexico. An average 56 hours was saved on each well, representing reductions of about 25% in completion time and 26% in completion cost per well. Time-sensitive costs had the largest impact on Green Canyon 52 A final well completion cost; therefore, new technology or more efficient operations were required to minimize completion time. One way to enhance project economics was to gravel pack two separate zones in one trip. In this paper, four objectives are addressed during development of a single trip tool to gravel pack the stacked zones of the Marquette project. These were time and cost reduction, removal of loss circulation material (LCM) prior to gravel packing, zone isolation during gravel packing and use of conventional gravel placement techniques. The design requirement that all LCM (salt and/or viscous polymer pills), perforation debris and formation sand be removed from the wellbore prior to gravel packing was accomplished by incorporating a washdown feature that allows circulation at the bottom of the gravel pack assembly prior to landing in the sump packer

  19. Large-Animal Biventricular Working Heart Perfusion System with Low Priming Volume-Comparison between in vivo and ex vivo Cardiac Function.

    Science.gov (United States)

    Abicht, Jan-Michael; Mayr, Tanja Axinja Jelena; Jauch, Judith; Guethoff, Sonja; Buchholz, Stefan; Reichart, Bruno; Bauer, Andreas

    2018-01-01

    Existing large-animal, ex vivo, cardiac perfusion models are restricted in their ability to establish an ischemia/reperfusion condition as seen in cardiac surgery or transplantation. Other working heart systems only challenge one ventricle or require a substantially larger priming volume. We describe a novel biventricular cardiac perfusion system with reduced priming volume. Juvenile pig hearts were cardiopleged, explanted, and reperfused ex vivo after 150 minutes of cold ischemia. Autologous whole blood was used as perfusate (minimal priming volume 350 mL). After 15 minutes of Langendorff perfusion (LM), the system was switched into a biventricular working mode (WM) and studied for 3 hours. During reperfusion, complete unloading of both ventricles and constant-pressure coronary perfusion was achieved. During working mode perfusion, the preload and afterload pressure of both ventricles was controlled within the targeted physiologic range. Functional parameters such as left ventricular work index were reduced in ex vivo working mode (in vivo: 787 ± 186 vs. 1 h WM 498 ± 66 mm Hg·mL/g·min; p  hours while functional and blood parameters are easily accessible. Moreover, because of the minimal priming volume, the novel ex vivo cardiac perfusion circuit allows for autologous perfusion, using the limited amount of blood available from the organ donating animal. Georg Thieme Verlag KG Stuttgart · New York.

  20. Site Environmental Report for 2008, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Lackner, Regina; Baskin, David; Fox, Robert; Jelinski, John; Pauer, Ron; Thorson, Patrick; Wahl, Linnea; Xu, Suying

    2009-09-21

    The Site Environmental Report for 2008 is an integrated report on the environmental programs at Lawrence Berkeley National Laboratory and satisfies the requirements of DOE order 231.1A, Environment, Safety, and Health Reporting. Volume II contains individual data results from surveillance and monitoring activities

  1. Monte Carlo Method with Heuristic Adjustment for Irregularly Shaped Food Product Volume Measurement

    Directory of Open Access Journals (Sweden)

    Joko Siswantoro

    2014-01-01

    Full Text Available Volume measurement plays an important role in the production and processing of food products. Various methods have been proposed to measure the volume of food products with irregular shapes based on 3D reconstruction. However, 3D reconstruction comes with a high-priced computational cost. Furthermore, some of the volume measurement methods based on 3D reconstruction have a low accuracy. Another method for measuring volume of objects uses Monte Carlo method. Monte Carlo method performs volume measurements using random points. Monte Carlo method only requires information regarding whether random points fall inside or outside an object and does not require a 3D reconstruction. This paper proposes volume measurement using a computer vision system for irregularly shaped food products without 3D reconstruction based on Monte Carlo method with heuristic adjustment. Five images of food product were captured using five cameras and processed to produce binary images. Monte Carlo integration with heuristic adjustment was performed to measure the volume based on the information extracted from binary images. The experimental results show that the proposed method provided high accuracy and precision compared to the water displacement method. In addition, the proposed method is more accurate and faster than the space carving method.

  2. Monte Carlo method with heuristic adjustment for irregularly shaped food product volume measurement.

    Science.gov (United States)

    Siswantoro, Joko; Prabuwono, Anton Satria; Abdullah, Azizi; Idrus, Bahari

    2014-01-01

    Volume measurement plays an important role in the production and processing of food products. Various methods have been proposed to measure the volume of food products with irregular shapes based on 3D reconstruction. However, 3D reconstruction comes with a high-priced computational cost. Furthermore, some of the volume measurement methods based on 3D reconstruction have a low accuracy. Another method for measuring volume of objects uses Monte Carlo method. Monte Carlo method performs volume measurements using random points. Monte Carlo method only requires information regarding whether random points fall inside or outside an object and does not require a 3D reconstruction. This paper proposes volume measurement using a computer vision system for irregularly shaped food products without 3D reconstruction based on Monte Carlo method with heuristic adjustment. Five images of food product were captured using five cameras and processed to produce binary images. Monte Carlo integration with heuristic adjustment was performed to measure the volume based on the information extracted from binary images. The experimental results show that the proposed method provided high accuracy and precision compared to the water displacement method. In addition, the proposed method is more accurate and faster than the space carving method.

  3. Partial Molar Volumes of Aqua Ions from First Principles.

    Science.gov (United States)

    Wiktor, Julia; Bruneval, Fabien; Pasquarello, Alfredo

    2017-08-08

    Partial molar volumes of ions in water solution are calculated through pressures obtained from ab initio molecular dynamics simulations. The correct definition of pressure in charged systems subject to periodic boundary conditions requires access to the variation of the electrostatic potential upon a change of volume. We develop a scheme for calculating such a variation in liquid systems by setting up an interface between regions of different density. This also allows us to determine the absolute deformation potentials for the band edges of liquid water. With the properly defined pressures, we obtain partial molar volumes of a series of aqua ions in very good agreement with experimental values.

  4. Approved Site Treatment Plan, Volumes 1 and 2. Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Helmich, E.H.; Molen, G.; Noller, D.

    1996-03-22

    The US Department of Energy, Savannah River Operations Office (DOE-SR), has prepared the Site Treatment Plan (STP) for Savannah River Site (SRS) mixed wastes in accordance with RCRA Section 3021(b), and SCDHEC has approved the STP (except for certain offsite wastes) and issued an order enforcing the STP commitments in Volume 1. DOE-SR and SCDHEC agree that this STP fulfills the requirements contained in the FFCAct, RCRA Section 3021, and therefore, pursuant to Section 105(a) of the FFCAct (RCRA Section 3021(b)(5)), DOE`s requirements are to implement the plan for the development of treatment capacities and technologies pursuant to RCRA Section 3021. Emerging and new technologies not yet considered may be identified to manage waste more safely, effectively, and at lower cost than technologies currently identified in the plan. DOE will continue to evaluate and develop technologies that offer potential advantages in public acceptance, privatization, consolidation, risk abatement, performance, and life-cycle cost. Should technologies that offer such advantages be identified, DOE may request a revision/modification of the STP in accordance with the provisions of Consent Order 95-22-HW. The Compliance Plan Volume (Volume 1) identifies project activity schedule milestones for achieving compliance with Land Disposal Restrictions (LDR). Information regarding the technical evaluation of treatment options for SRS mixed wastes is contained in the Background Volume (Volume 2) and is provided for information.

  5. Approved Site Treatment Plan, Volumes 1 and 2. Revision 4

    International Nuclear Information System (INIS)

    Helmich, E.H.; Molen, G.; Noller, D.

    1996-01-01

    The US Department of Energy, Savannah River Operations Office (DOE-SR), has prepared the Site Treatment Plan (STP) for Savannah River Site (SRS) mixed wastes in accordance with RCRA Section 3021(b), and SCDHEC has approved the STP (except for certain offsite wastes) and issued an order enforcing the STP commitments in Volume 1. DOE-SR and SCDHEC agree that this STP fulfills the requirements contained in the FFCAct, RCRA Section 3021, and therefore, pursuant to Section 105(a) of the FFCAct (RCRA Section 3021(b)(5)), DOE's requirements are to implement the plan for the development of treatment capacities and technologies pursuant to RCRA Section 3021. Emerging and new technologies not yet considered may be identified to manage waste more safely, effectively, and at lower cost than technologies currently identified in the plan. DOE will continue to evaluate and develop technologies that offer potential advantages in public acceptance, privatization, consolidation, risk abatement, performance, and life-cycle cost. Should technologies that offer such advantages be identified, DOE may request a revision/modification of the STP in accordance with the provisions of Consent Order 95-22-HW. The Compliance Plan Volume (Volume 1) identifies project activity schedule milestones for achieving compliance with Land Disposal Restrictions (LDR). Information regarding the technical evaluation of treatment options for SRS mixed wastes is contained in the Background Volume (Volume 2) and is provided for information

  6. 48 CFR 44.302 - Requirements.

    Science.gov (United States)

    2010-10-01

    ... during the next 12 months, perform a review to determine if a CPSR is needed. Sales include those... SUBCONTRACTING POLICIES AND PROCEDURES Contractors' Purchasing Systems Reviews 44.302 Requirements. (a) The ACO..., and the volume, complexity and dollar value of subcontracts. If a contractor's sales to the Government...

  7. Arrhenius Rate: constant volume burn

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-12-06

    A constant volume burn occurs for an idealized initial state in which a large volume of reactants at rest is suddenly raised to a high temperature and begins to burn. Due to the uniform spatial state, there is no fluid motion and no heat conduction. This reduces the time evolu tion to an ODE for the reaction progress variable. With an Arrhenius reaction rate, two characteristics of thermal ignition are illustrated: induction time and thermal runaway. The Frank-Kamenetskii approximation then leads to a simple expression for the adiabatic induction time. For a first order reaction, the analytic solution is derived and used to illustrate the effect of varying the activation temperature; in particular, on the induction time. In general, the ODE can be solved numerically. This is used to illustrate the effect of varying the reaction order. We note that for a first order reaction, the time evolution of the reaction progress variable has an exponential tail. In contrast, for a reaction order less than one, the reaction completes in a nite time. The reaction order also affects the induction time.

  8. 40 CFR 86.1838-01 - Small volume manufacturer certification procedures.

    Science.gov (United States)

    2010-07-01

    ...-Duty Vehicles, Light-Duty Trucks, and Complete Otto-Cycle Heavy-Duty Vehicles § 86.1838-01 Small volume... companies; (iv) Vehicles and/or engines imported or distributed by all firms where the vehicles and/or...-use verification testing to have a minimum odometer mileage of 75 percent of the full useful life...

  9. Cell volume regulation in hemoglobin CC and AA erythrocytes

    International Nuclear Information System (INIS)

    Berkowitz, L.R.; Orringer, E.P.

    1987-01-01

    Swelling hemoglobin CC erythrocytes stimulates a ouabain-insensitive K flux that restores original cell volume. Studies were performed with the K analog, 86 Rb. This volume regulatory pathway was characterized for its anion dependence, sensitivity to loop diuretics, and requirement for Na. The swelling-induced K flux was eliminated if intracellular chloride was replaced by nitrate and both swelling-activated K influx and efflux were partially inhibited by 1 mM furosemide or bumetanide. K influx in swollen hemoglobin CC cells was not diminished when Na in the incubation medium was replaced with choline, indicating Na independence of the swelling-induced flux. Identical experiments with hemoglobin AA cells also demonstrated a swelling-induced increase in K flux, but the magnitude and duration of this increase were considerably less than that seen with hemoglobin CC cells. The increased K flux in hemoglobin AA cells was likewise sensitive to anion replacement and to loop diuretics and did not require the presence of Na. These data indicate that a volume-activated K pathway with similar transport characteristics exists in both hemoglobin CC and AA red cells

  10. Prostate cancer: Doses and volumes of radiotherapy

    International Nuclear Information System (INIS)

    Hennequin, C.; Rivera, S.; Quero, L.; Latorzeff, I.

    2010-01-01

    Radiotherapy is nowadays a major therapeutic option in prostate cancer. Technological improvements allowed dose escalation without increasing late toxicity. Some randomized trials have shown that dose escalation decreases the biochemical failure rate, without any benefit in survival with the present follow-up. However, some studies indicate that the distant metastases rate is also decreased. Most of these studies have been done without hormonal treatment, and the role of dose escalation in case of long-term androgen deprivation is unknown. The target volume encompassed the whole gland: however, complete or partial focal treatment of the prostate can be done with sophisticated IMRT technique and must be evaluated. Proximal part of the seminal vesicles must be included in the target volumes. The role of nodal irradiation is another debate, but it could be logically proposed for the unfavourable group. (authors)

  11. The design, development, and test of balloonborne and groundbased lidar systems. Volume 1: Balloonborne coherent CO2 lidar system

    Science.gov (United States)

    Shepherd, O.; Aurilio, G.; Bucknam, R. D.; Hurd, A. G.; Rappaport, S. A.

    1991-06-01

    This is Volume 1 of a three volume final report on the design, development, and test of balloonborne and groundbased lidar systems. Volume 2 describes the flight test of Atmospheric Balloonborne Lidar Experiment, ABLE 2, which successfully made atmospheric density backscatter measurements during a flight over White Sands Missile Range. Volume 3 describes groundbased lidar development and measurements, including the design of a telescope dome lidar installation, the design of a transportable lidar shed for remote field sites, and field measurements of atmospheric and cloud backscatter from Ascension Island during SABLE 89 and Terciera, Azores during GABLE 90. In this volume, Volume 1, the design and fabrication of a balloonborne CO2 coherent lidar payload are described. The purpose of this payload is to measure, from altitudes greater than 20 km, the 10.6 micrometers backscatter from atmospheric aerosols as a function of altitude. Minor modifications to the lidar would provide for aerosol velocity measurements to be made. The lidar and payload system design was completed, and major components were fabricated and assembled. These tasks have been successfully completed, and recommendations for further lidar measurements and data analysis have been made.

  12. The complete guide to using Google in libraries instruction, administration, and staff productivity

    CERN Document Server

    Smallwood, Carol

    2015-01-01

    Carol Smallwood's The Complete Guide to Using Google in Libraries, Volume 1: Instruction, Administration, and Staff Productivity explores how Google's suite of tools, from Google Docs (now Google Drive), Google Scholar, Hangout, Forms, and others made freely available to the Internet Community, can be used by libraries to expand the role of digital operations in the management of library materials, to communicate with their patrons and collaborators, to exploit the resources on the Web, and many others.

  13. Prospects of complete feed system in ruminant feeding: A review

    Directory of Open Access Journals (Sweden)

    Yasir Afzal Beigh

    2017-04-01

    Full Text Available Effective utilization of available feed resources is the key for economical livestock rearing. Complete feed system is one of the latest developments to exploit the potential of animal feed resources in the best possible way. The complete feed is a quantitative mixture of all dietary ingredients, blended thoroughly to prevent separation and selection, fed as a sole source of nutrients except water and is formulated in a desired proportion to meet the specific nutrient requirements. The concentrate and roughage levels may vary according to the nutrient requirement of ruminants for different production purposes. The complete feed with the use of fibrous crop residue is a noble way to increase the voluntary feed intake and thus animal's production performance. In this system of feeding, the ruminant animals have continuous free choice availability of uniform feed mixture, resulting in more uniform load on the rumen and less fluctuation in release of ammonia which supports more efficient utilization of ruminal non-protein nitrogen. Feeding complete diet stabilizes ruminal fermentation, thereby improves nutrient utilization. This feeding system allows expanded use of agro-industrial byproducts, crop residues and nonconventional feeds in ruminant ration for maximizing production and minimizing feeding cost, thus being increasingly appreciated. However, to extend the concept extensively to the field and make this technology successful and viable for farmers, more efforts are needed to be taken.

  14. Determining how much mixed waste will require disposal

    International Nuclear Information System (INIS)

    Kirner, N.P.

    1990-01-01

    Estimating needed mixed-waste disposal capacity to 1995 and beyond is an essential element in the safe management of low-level radioactive waste disposal capacity. Information on the types and quantities of mixed waste generated is needed by industry to allow development of treatment facilities and by states and others responsible for disposal and storage of this type of low-level radioactive waste. The design of a mixed waste disposal facility hinges on a detailed assessment of the types and quantities of mixed waste that will ultimately require land disposal. Although traditional liquid scintillation counting fluids using toluene and xylene are clearly recognized as mixed waste, characterization of other types of mixed waste has, however, been difficult. Liquid scintillation counting fluids comprise most of the mixed waste generated and this type of mixed waste is generally incinerated under the supplemental fuel provisions of the Resource Conservation and Recovery Act (RCRA) Because there are no Currently operating mixed waste land disposal facilities, it is impossible to make projections of waste requiring land disposal based on a continuation of current waste disposal practices. Evidence indicates the volume of mixed waste requiring land disposal is not large, since generators are apparently storing these wastes. Surveys conducted to date confirm that relatively small volumes of commercially generated mixed waste volume have relied heavily oil generators' knowledge of their wastes. Evidence exists that many generators are confused by the differences between the Atomic Energy Act and the Resource Conservation and Recovery Act (RCRA) on the issue of when a material becomes a waste. In spite of uncertainties, estimates of waste volumes requiring disposal can be made. This paper proposes an eight-step process for such estimates

  15. The Relationship Between the Gensini Score and Complete Blood Count Parameters in Coronary Artery Disease

    Directory of Open Access Journals (Sweden)

    Muhammet Raşit Sayın

    2012-08-01

    Full Text Available Introduction: The aim of this study was to evaluate the relationship between the extend andseverity of coronary artery disease (CAD determined by the Gensini score and complete bloodcount parameters (white blood cell, hemoglobin, platelet, mean platelet volume, lymphocyte,neutrophil.Patients and Methods: Ninety patients with CAD underwent coronary angiography (40 females,mean age 61 ± 1.2 years were included in this study. Patients with acute coronary syndrome andprior cardiovascular disease excluded from the study. The association between the extent andseverity of CAD, which were assessed by the Gensini score, and complete blood count parameterswas analyzed by a correlation analysis.Results: Coronary angiography revealed, 6 (6.7% patients had three, 16 (17.8% patients hadtwo, and 24 (26.7% patients had single-vessel disease; 44 (48.9% patients had non-criticalstenosis. The mean Gensini score was 19.1 ± 2.1. We found a relationship between white bloodcell and neutrophil counts and the Gensini score. There was no relationship between Gensiniscore and the mean platelet volume and other parameters.Conclusion: The present study supports the hypothesis that inflammation is one of the maincomponent in the pathogenesis of CAD.

  16. Long-Term Treatment with Paroxetine Increases Verbal Declarative Memory and Hippocampal Volume in Posttraumatic Stress Disorder

    Science.gov (United States)

    Vermetten, Eric; Vythilingam, Meena; Southwick, Steven M.; Charney, Dennis S.; Bremner, J. Douglas

    2011-01-01

    Background Animal studies have shown that stress is associated with damage to the hippocampus, inhibition of neurogenesis, and deficits in hippocampal-based memory dysfunction. Studies in patients with posttraumatic stress disorder (PTSD) found deficits in hippocampal-based declarative verbal memory and smaller hippocampal volume, as measured with magnetic resonance imaging (MRI). Recent preclinical evidence has shown that selective serotonin reuptake inhibitors promote neurogenesis and reverse the effects of stress on hippocampal atrophy. This study assessed the effects of long-term treatment with paroxetine on hippocampal volume and declarative memory performance in PTSD. Methods Declarative memory was assessed with the Wechsler Memory Scale–Revised and Selective Reminding Test before and after 9–12 months of treatment with paroxetine in PTSD. Hippocampal volume was measured with MRI. Of the 28 patients who started the protocol, 23 completed the full course of treatment and neuropsychological testing. Twenty patients were able to complete MRI imaging. Results Patients with PTSD showed a significant improvement in PTSD symptoms with treatment. Treatment resulted in significant improvements in verbal declarative memory and a 4.6% increase in mean hippocampal volume. Conclusions These findings suggest that long-term treatment with paroxetine is associated with improvement of verbal declarative memory deficits and an increase in hippocampal volume in PTSD. PMID:14512209

  17. 40 CFR 63.655 - Reporting and recordkeeping requirements.

    Science.gov (United States)

    2010-07-01

    ... operating conditions. (A) The percentage of reduction of organic HAP's or TOC, or the outlet concentration of organic HAP's or TOC (parts per million by volume on a dry basis corrected to 3 percent oxygen... planned routine maintenance operations that would require the control device not to meet the requirements...

  18. The Role of New Removable Complete Dentures in Stimulated Salivary Flow and Taste Perception.

    Science.gov (United States)

    Tango, Rubens Nisie; Arata, Anelyse; Borges, Alexandre Luiz Souto; Costa, Anna K F; Pereira, Luciano Jose; Kaminagakura, Estela

    2018-04-01

    To evaluate the effect of replacement of inadequate complete dentures on salivary flow and taste perception in geriatric patients. Thirty-three patients, 13 males and 20 females, with a mean age of 64.4 years were submitted to stimulated and unstimulated salivary flow rate and salivary pH measurements, and sense of taste evaluation. Tests were performed 3 months before complete denture substitution and 3 weeks after denture insertion. The mean for unstimulated saliva (USS) was 2.1 ml before and 2.7 ml after replacement (p = 0.003). The mean volume of stimulated saliva was 6.3 ml before and 8.2 ml after replacement (p = 0.004). The pH mean of USS was 7.8 ± 0.44 before and 8.02 ± 0.41 after replacement (p = 0.005). No statistically significant difference was determined in the sense of taste before and 3 weeks after complete denture replacement. The replacement of inadequate complete dentures increases saliva flow; however, it does not improve taste perception. © 2016 by the American College of Prosthodontists.

  19. Load research manual. Volume 1. Load research procedures

    Energy Technology Data Exchange (ETDEWEB)

    Brandenburg, L.; Clarkson, G.; Grund, Jr., C.; Leo, J.; Asbury, J.; Brandon-Brown, F.; Derderian, H.; Mueller, R.; Swaroop, R.

    1980-11-01

    This three-volume manual presents technical guidelines for electric utility load research. Special attention is given to issues raised by the load data reporting requirements of the Public Utility Regulatory Policies Act of 1978 and to problems faced by smaller utilities that are initiating load research programs. In Volumes 1 and 2, procedures are suggested for determining data requirements for load research, establishing the size and customer composition of a load survey sample, selecting and using equipment to record customer electricity usage, processing data tapes from the recording equipment, and analyzing the data. Statistical techniques used in customer sampling are discussed in detail. The costs of load research also are estimated, and ongoing load research programs at three utilities are described. The manual includes guides to load research literature and glossaries of load research and statistical terms.

  20. Feasibility of developing a portable driver performance data acquisition system for human factors research: Technical tasks. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Carter, R.J.; Barickman, F.S.; Spelt, P.F.; Schmoyer, R.L.; Kirkpatrick, J.R.

    1998-01-01

    A two-phase, multi-year research program entitled ``development of a portable driver performance data acquisition system for human factors research`` was recently completed. The primary objective of the project was to develop a portable data acquisition system for crash avoidance research (DASCAR) that will allow drive performance data to be collected using a large variety of vehicle types and that would be capable of being installed on a given vehicle type within a relatively short-time frame. During phase 1 a feasibility study for designing and fabricating DASCAR was conducted. In phase 2 of the research DASCAR was actually developed and validated. This technical memorandum documents the results from the feasibility study. It is subdivided into three volumes. Volume one (this report) addresses the last five items in the phase 1 research and the first issue in the second phase of the project. Volumes two and three present the related appendices, and the design specifications developed for DASCAR respectively. The six tasks were oriented toward: identifying parameters and measures; identifying analysis tools and methods; identifying measurement techniques and state-of-the-art hardware and software; developing design requirements and specifications; determining the cost of one or more copies of the proposed data acquisition system; and designing a development plan and constructing DASCAR. This report also covers: the background to the program; the requirements for the project; micro camera testing; heat load calculations for the DASCAR instrumentation package in automobile trunks; phase 2 of the research; the DASCAR hardware and software delivered to the National Highway Traffic Safety Administration; and crash avoidance problems that can be addressed by DASCAR.

  1. Recommended criteria for the evaluation of on-site nuclear power plant emergency plans, volume II: criteria

    International Nuclear Information System (INIS)

    1997-01-01

    A critical review of existing Canadian and international nuclear power plant (NPP) emergency plans, evaluation criteria, and approaches has been conducted to provide AECB staff with information which can be used to assess the adequacy of NPP on-site emergency response plans. The results of this work are published in two volumes. Volume I, Basis Document, provides the reasons why certain requirements are in place. It also gives comprehensive references to various standards.Volume II, Criteria, contains the criteria which relate to on-site actions and their integration with control room activities and the roles of off-site responsible organizations. The recommended criteria provide information on what is required, and not on how to accomplish the requirements. The licensees are given the latitude to decide on the methods and processes needed to meet the requirements. The documents do not address NPP off-site plans and response capability, or the control room emergency operating procedures and response capability. This report contains only Volume II: Criteria. 55 refs., 2 tabs., 1 fig

  2. Planning target volumes for radiotherapy: how much margin is needed?

    International Nuclear Information System (INIS)

    Antolak, John A.; Rosen, Isaac I.

    1999-01-01

    Purpose: The radiotherapy planning target volume (PTV) encloses the clinical target volume (CTV) with anisotropic margins to account for possible uncertainties in beam alignment, patient positioning, organ motion, and organ deformation. Ideally, the CTV-PTV margin should be determined solely by the magnitudes of the uncertainties involved. In practice, the clinician usually also considers doses to abutting healthy tissues when deciding on the size of the CTV-PTV margin. This study calculates the ideal size of the CTV-PTV margin when only physical position uncertainties are considered. Methods and Materials: The position of the CTV for any treatment is assumed to be described by independent Gaussian distributions in each of the three Cartesian directions. Three strategies for choosing a CTV-PTV margin are analyzed. The CTV-PTV margin can be based on: 1. the probability that the CTV is completely enclosed by the PTV; 2. the probability that the projection of the CTV in the beam's eye view (BEV) is completely enclosed by the projection of the PTV in the BEV; and 3. the probability that a point on the edge of the CTV is within the PTV. Cumulative probability distributions are derived for each of the above strategies. Results: Expansion of the CTV by 1 standard deviation (SD) in each direction results in the CTV being entirely enclosed within the PTV 24% of the time; the BEV projection of the CTV is enclosed within the BEV projection of the PTV 39% of the time; and a point on the edge of the CTV is within the PTV 84% of the time. To have the CTV enclosed entirely within the PTV 95% of the time requires a margin of 2.8 SD. For the BEV projection of the CTV to be within the BEV projection of the PTV 95% of the time requires a margin of 2.45 SD. To have any point on the surface of the CTV be within the PTV 95% of the time requires a margin of 1.65 SD. Conclusion: In the first two strategies for selecting a margin, the probability of finding the CTV within the PTV is

  3. Quantifying normal ankle joint volume: An anatomic study

    Directory of Open Access Journals (Sweden)

    Draeger Reid

    2009-01-01

    Full Text Available Background: Many therapeutic and diagnostic modalities such as intraarticular injections, arthrography and ankle arthroscopy require introduction of fluid into the ankle joint. Little data are currently available in the literature regarding the maximal volume of normal, nonpathologic, human ankle joints. The purpose of this study was to measure the volume of normal human ankle joints. Materials and Methods: A fluoroscopic guided needle was passed into nine cadaveric adult ankle joints. The needle was connected to an intracompartmental pressure measurement device. A radiopaque dye was introduced into the joint in 2 mL boluses, while pressure measurements were recorded. Fluid was injected into the joint until three consecutive pressure measurements were similar, signifying a maximal joint volume. Results: The mean maximum ankle joint volume was 20.9 ± 4.9 mL (range, 16-30 mL. The mean ankle joint pressure at maximum volume was 142.2 ± 13.8 mm Hg (range, 122-166 mm Hg. Two of the nine samples showed evidence of fluid tracking into the synovial sheath of the flexor hallucis longus tendon. Conclusion: Maximal normal ankle joint volume was found to vary between 16-30 mL. This study ascertains the communication between the ankle joint and the flexor hallucis longus tendon sheath. Exceeding maximal ankle joint volume suggested by this study during therapeutic injections, arthrography, or arthroscopy could potentially damage the joint.

  4. Individual Global Navigation Satellite Systems in the Space Service Volume

    Science.gov (United States)

    Force, Dale A.

    2015-01-01

    Besides providing position, navigation, and timing (PNT) to terrestrial users, GPS is currently used to provide for precision orbit determination, precise time synchronization, real-time spacecraft navigation, and three-axis control of Earth orbiting satellites. With additional Global Navigation Satellite Systems (GNSS) coming into service (GLONASS, Beidou, and Galileo), it will be possible to provide these services by using other GNSS constellations. The paper, "GPS in the Space Service Volume," presented at the ION GNSS 19th International Technical Meeting in 2006 (Ref. 1), defined the Space Service Volume, and analyzed the performance of GPS out to 70,000 km. This paper will report a similar analysis of the performance of each of the additional GNSS and compare them with GPS alone. The Space Service Volume, defined as the volume between 3,000 km altitude and geosynchronous altitude, as compared with the Terrestrial Service Volume between the surface and 3,000 km. In the Terrestrial Service Volume, GNSS performance will be similar to performance on the Earth's surface. The GPS system has established signal requirements for the Space Service Volume. A separate paper presented at the conference covers the use of multiple GNSS in the Space Service Volume.

  5. Positive pressure ventilation and cranial volume in newborn infants.

    OpenAIRE

    Milligan, D W

    1981-01-01

    The relationship between changes in airways pressure, pleural pressure, and cranial volume was studied in a group of sick newborn infants requiring ventilatory assistance. Cranial volume increased appreciably only when lung compliance was such that more than 20% of the applied airways pressure was transmitted to the pleural space, or if the absolute pleural pressure was greater than 4 cmH2O above atmospheric pressure. The findings stress the need for more-critical monitoring during periods of...

  6. Left ventricular volume determination from single-photon emission computed tomography

    International Nuclear Information System (INIS)

    Bunker, S.R.; Hartshorne, M.F.; Schmidt, W.P.; Cawthon, M.A.; Karl, R.D. Jr.; Bauman, J.M.; Howard, W.H. III; Rubal, B.J.

    1985-01-01

    To compare the accuracy of single-photon emission computed tomography (SPECT) with that of contrast cineangiography in measuring left ventricular end-diastolic volume, 25 consecutive patients undergoing catheterizaiton for coronary artery or valvular heart disease were first evaluated scintigraphically. SPECT volume values showed a high degree of correlation with those determined by angiography with a standard error of the estimate of 23 ml. SPECT offers a highly accurate and essentially noninvasive method for measuring chamber volumes that is independent of geometric assumptions about ventricular configuration and chest wall attenuation and does not require blood sample counting

  7. Left ventricular volume determination from single-photon emission computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Bunker, S.R.; Hartshorne, M.F.; Schmidt, W.P.; Cawthon, M.A.; Karl, R.D. Jr.; Bauman, J.M.; Howard, W.H. III; Rubal, B.J.

    1985-02-01

    To compare the accuracy of single-photon emission computed tomography (SPECT) with that of contrast cineangiography in measuring left ventricular end-diastolic volume, 25 consecutive patients undergoing catheterizaiton for coronary artery or valvular heart disease were first evaluated scintigraphically. SPECT volume values showed a high degree of correlation with those determined by angiography with a standard error of the estimate of 23 ml. SPECT offers a highly accurate and essentially noninvasive method for measuring chamber volumes that is independent of geometric assumptions about ventricular configuration and chest wall attenuation and does not require blood sample counting.

  8. Nuclear criticality safety experiments, calculations, and analyses: 1958 to 1982. Volume 1. Lookup tables

    International Nuclear Information System (INIS)

    Koponen, B.L.; Hampel, V.E.

    1982-01-01

    This compilation contains 688 complete summaries of papers on nuclear criticality safety as presented at meetings of the American Nuclear Society (ANS). The selected papers contain criticality parameters for fissile materials derived from experiments and calculations, as well as criticality safety analyses for fissile material processing, transport, and storage. The compilation was developed as a component of the Nuclear Criticality Information System (NCIS) now under development at the Lawrence Livermore National Laboratory. The compilation is presented in two volumes: Volume 1 contains a directory to the ANS Transaction volume and page number where each summary was originally published, the author concordance, and the subject concordance derived from the keyphrases in titles. Volume 2 contains - in chronological order - the full-text summaries, reproduced here by permission of the American Nuclear Society from their Transactions, volumes 1-41

  9. Humidification and secretion volume in mechanically ventilated patients.

    Science.gov (United States)

    Solomita, Mario; Palmer, Lucy B; Daroowalla, Feroza; Liu, Jeffrey; Miller, Dori; LeBlanc, Deniese S; Smaldone, Gerald C

    2009-10-01

    To determine potential effects of humidification on the volume of airway secretions in mechanically ventilated patients. Water vapor delivery from devices providing non-heated-wire humidification, heated-wire humidification, and heat and moisture exchanger (HME) were quantified on the bench. Then, patients requiring 24-hour mechanical ventilation were exposed sequentially to each of these humidification devices, and secretions were removed and measured by suctioning every hour during the last 4 hours of the 24-hour study period. In vitro water vapor delivery was greater using non-heated-wire humidification, compared to heated-wire humidification and HME. In vivo, a total of 9 patients were studied. Secretion volume following humidification by non-heated-wire humidification was significantly greater than for heated-wire humidification and HME (P=.004). The volume of secretions appeared to be linked to humidification, as greater water vapor delivery measured in vitro was associated with greater secretion volume in vivo.

  10. Resource Conservation and Recovery Act ground-water monitoring projects for Hanford Facilities: Progress report for the period July 1 to September 30, 1989 - Volume 1 - Text

    Energy Technology Data Exchange (ETDEWEB)

    Smith, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-12-01

    This is Volume 1 of a two-volume document that describes the progress of 14 Hanford Site ground-water monitoring projects for the period July 1 to September 30, 1989. This volume discusses the projects; Volume 2 provides as-built diagrams, completion/inspection reports, drilling logs, and geophysical logs for wells drilled, completed, or logged during this period. Volume 2 can be found on microfiche in the back pocket of Volume 1. The work described in this document is conducted by the Pacific Northwest Laboratory under the management of Westinghouse Hanford Company for the US Department of Energy. Concentrations of ground-water constituents are compared to federal drinking water standards throughout this document for reference purposes. All drinking water supplied from the sampled aquifer meets regulatory standards for drinking water quality.

  11. On the relationship between investor sentiment, VIX and trading volume.

    Directory of Open Access Journals (Sweden)

    Simon Man Shing So

    2015-11-01

    Full Text Available As noise traders affect stock market by trading, sentiment, as a signal of noise, may have relationships with trading volume. This paper explores the effect of sentiment on the stock market’s trading volume. Increase in Volatility Index (VIX can explain the percentage increase in trading volume, but only in high VIX period. Besides, higher level of VIX is likely to be associated with greater variability of trading volume. The noise traders add liquidity to the market and provide more chances for investors to time their trade as the volatility of liquidity increases. These two kinds of impact lower rational investors’ required return. The noise traders not only drive the price deviating from fundamental value, but also influence the liquidity dimensions.

  12. A feasibility study for the design of a simulated radioactive waste repository facility. Volume 1 Text-References

    International Nuclear Information System (INIS)

    Mott; Hay; Anderson.

    1987-01-01

    The report is in two volumes: Volume 1 contains the main text and the references, and volume 2, all the figures and tables. The great majority of published concepts for the disposal of heat generating radioactive waste envisage the emplacement of waste packages in boreholes backfilled with an engineered material described as the buffer. The need for a full scale experimental programme to investigate buffer placement and performance was identified, and this report describes the first stage in the development of that programme. The nature of candidate buffer materials and the factors defining their behaviour have been reviewed and the nature of a buffer material selection and testing programme have been outlined. The properties of crystalline rocks, saliferous formations and clay host materials have been reviewed and the complex interactions between them have been identified. The difficulty of modelling these properties and the interaction between buffer and host materials has been discussed and the instrumentation requirements for measuring this interaction have been outlined. A limited amount of thermomechanical analysis has been performed to give a preliminary indication of the parameters of major significance in selection of instrumentation and modelling materials. It has been concluded that a complete simulation of host material properties is not presently viable, although it may be attainable for some crystalline rock types. Alternative strategies for assessment of the host/buffer interaction are suggested

  13. Breastfeeding and Childhood IQ: The Mediating Role of Gray Matter Volume

    Science.gov (United States)

    Luby, Joan L.; Belden, Andy C.; Whalen, Diana; Harms, Michael P.; Barch, Deanna M.

    2016-01-01

    Objective A substantial body of literature has established the positive effect of breastfeeding on child developmental outcomes. There is increasing consensus that breastfed children have higher IQs after accounting for key variables, including maternal education, IQ, and socioeconomic status. Cross-sectional investigations of the effects of breastfeeding on structural brain development suggest that breastfed infants have larger whole brain, cortical, and white matter volumes. To date, few studies have related these measures of brain structure to IQ in breastfed versus nonbreastfed children in a longitudinal sample. Method Data were derived from the Preschool Depression Study (PDS), a prospective longitudinal study in which children and caregivers were assessed annually for 8 waves over 11 years. A subset completed neuroimaging between the ages of 9.5 and 14.11 years. A total of 148 individuals had breastfeeding data at baseline and complete data on all variables of interest, including IQ and structural neuroimaging. General linear models and process mediation models were used. Results Breastfed children had significantly higher IQ scores and larger whole brain, total gray matter, total cortical gray matter, and subcortical gray matter volumes compared with the nonbreastfed group in models that covaried for key variables. Subcortical gray matter volume significantly mediated the association between breast-feeding and children's IQ scores. Conclusion The study findings suggest that the effects of breastfeeding on child IQ are mediated through subcortical gray volume. This effect and putative mechanism is of public health significance and further supports the importance of breastfeeding in mental health promotion. PMID:27126850

  14. When high-volume PCI operators in high-volume hospitals move to lower volume hospitals-Do they still maintain high volume and quality of outcomes?

    Science.gov (United States)

    Lu, Tsung-Hsueh; Li, Sheng-Tun; Liang, Fu-Wen; Lee, Jo-Chi; Yin, Wei-Hsian

    2017-10-31

    The aim of this quasi-experimental study was to examine whether high-volume percutaneous coronary intervention (PCI) operators still maintain high volume and quality of outcomes when they moved to lower volume hospitals. Systematic reviews have indicated that high-volume PCI operators and hospitals have higher quality outcomes. However, little is known on whether high PCI volume and high quality outcomes are mainly due to operator characteristics (i.e., skill and experience) and is portable across organizations or whether it is due to hospital characteristics (i.e., equipment, team, and management system) and is less portable. We used Taiwan National Health Insurance claims data 2000-2012 to identify 98 high-volume PCI operators, 10 of whom moved from one hospital to another during the study period. We compared the PCI volume, risk-adjusted mortality ratio, and major adverse cardiovascular event (MACE) ratio before and after moving. Of the 10 high-volume operators who moved, 6 moved from high- to moderate- or low-volume hospitals, with median annual PCI volumes (interquartile range) of 130 (117-165) in prior hospitals and 54 (46-84) in subsequent hospitals (the hospital the operator moved to), and the remaining 4 moved from high to high-volume hospitals, with median annual PCI volumes (interquartile range) of 151 (133-162) in prior hospitals and 193 (178-239) in subsequent hospitals. No significant differences were observed in the risk-adjusted mortality ratios and MACE ratios between high-volume operators and matched controls before and after moving. High-volume operators cannot maintain high volume when they moved from high to moderate or low-volume hospitals; however, the quality of care is maintained. High PCI volume and high-quality outcomes are less portable and more hospital bound. © 2017 Wiley Periodicals, Inc.

  15. Proceedings of the natural gas RD&D contractors review meeting, Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Malone, R.D. [ed.

    1995-04-01

    This is volume II of papers which were presented at the natural gas RD&D contractors review meeting. Topics include: natural gas upgrading, storage, well drilling, completion, and stimulation. Individual papers were processed separately for the United States Department of Energy databases.

  16. Evaluation of a new software tool for the automatic volume calculation of hepatic tumors. First results

    International Nuclear Information System (INIS)

    Meier, S.; Mildenberger, P.; Pitton, M.; Thelen, M.; Schenk, A.; Bourquain, H.

    2004-01-01

    Purpose: computed tomography has become the preferred method in detecting liver carcinomas. The introduction of spiral CT added volumetric assessment of intrahepatic tumors, which was unattainable in the clinical routine with incremental CT due to complex planimetric revisions and excessive computing time. In an ongoing clinical study, a new software tool was tested for the automatic detection of tumor volume and the time needed for this procedure. Materials and methods: we analyzed patients suffering from hepatocellular carcinoma (HCC). All patients underwent treatment with repeated transcatheter chemoembolization of the hepatic arteria. The volumes of the HCC lesions detected in CT were measured with the new software tool in HepaVison (MeVis, Germany). The results were compared with manual planimetric calculation of the volume performed by three independent radiologists. Results: our first results in 16 patients show a correlation between the automatically and the manually calculated volumes (up to a difference of 2 ml) of 96.8%. While the manual method of analyzing the volume of a lesion requires 2.5 minutes on average, the automatic method merely requires about 30 seconds of user interaction time. Conclusion: These preliminary results show a good correlation between automatic and manual calculations of the tumor volume. The new software tool requires less time for accurate determination of the tumor volume and can be applied in the daily clinical routine. (orig.) [de

  17. Nutritional requirements and parenteral nutrition in preterm infants ...

    African Journals Online (AJOL)

    Provision of appropriate nutritional requirements soon after birth is critical for normal development and growth of preterm infants. Preterm infants are often not able to tolerate volumes of oral feeds that will provide adequate daily requirements for growth within the first week or two of life, therefore parenteral nutrition is often ...

  18. Test design requirements for overcoring stress measurements

    International Nuclear Information System (INIS)

    Stickney, R.G.

    1985-12-01

    This document establishes the test design requirements for a series of overcoring stress measurements to be performed in the Exploratory Shaft Facility. The stress measurements will be made to determine the in situ state of stress within the candidate repository horizon and to determine the magnitude and distribution of the stresses induced by the mined openings of the facility. The overcoring technique involves the measurement of strain (or deformation) in a volume of rock as the stress acting on the rock volume is relieved. This document presents an overview of the measurements, including objectives and rationale for the measurements. A description of the measurements is included. The support requirements are identified as are constraints for the design of the measurements. Discussions on Quality Assurance and Safety are also included in the document. 13 refs

  19. TMI-related requirements for new operating licenses. Technical report

    International Nuclear Information System (INIS)

    1980-06-01

    There are four types of TMI-related requirements and actions approved by the Commission for new operating licenses: (1) those required to be completed by a license applicant prior to receiving a fuel-loading and low-power testing license, (2) those required to be completed by a license applicant prior to receiving a license to operate at appreciable power levels up to full power, (3) those the NRC will take prior to issuing a fuel-loading and low-power testing or a full-power operating license, and (4) those required to be completed by a licensee prior to a specified date. In this report, only those dated requirements that have already been issued are of interest. Other dated requirements are expected to be issued in the future as work progresses in accordance with the TMI Action Plan. This report summarizes the several parts of the list of TMI-related requirements approved by the Commission for new operating licenses

  20. Comparison of six methods of segmentation of tumor volume on the {sup 18}F-F.D.G. PET scan with reference histological volume in non small cell bronchopulmonary cancers; Comparaison de six methodes de segmentation du volume tumoral sur la {sup 18}F-FDG TEP-TDM avec le volume de reference anatomopathologique dans les cancers bronchopulmonaires non a petites cellules

    Energy Technology Data Exchange (ETDEWEB)

    Venel, Y.; Garhi, H.; Baulieu, J.L.; Prunier-Aesch, C. [CHRU de Tours-Bretonneau, Service de Medecine Nucleaire, 37 - Tours (France); Muret, A. de [CHRU de Tours-Bretonneau, Service de Radiotherapie, 37 - Tours (France); Barillot, I. [CHRU de Tours-Bretonneau, Service d' Anatomopathologie, 37 - Tours (France)

    2008-06-15

    The {sup 18}F-F.D.G. PET has demonstrated its importance in oncology, for initial extension and efficacy of anti tumoral therapeutics. Several studies have attempted to prove its utility to define tumoral volumes for conformational radiotherapy in non small cell lung cancers. Some authors have suggested the use of threshold of tumor intensity uptake with 40 or 50% of maximal intensity. Black et al. have determined contouring with linear regression formula of mean semi-quantitative index of tumor uptake (standard uptake value): SUV{sub threshold} = 0.307 Sub{sub average} + 0.588. Nestle et al. have taken into account the background noise intensity and mean intensity of the tumor: I{sub threshold} = {beta} I{sub average} +I{sub noise} with {beta} 0.15. Our study was done in collaboration with Inserm U618 team and has compared volumes defined on PET scan defined according to different methods based on intensity or S.U.V. to the tumour volume determined on CT scan by radio physicist. We have compared those volumes with histological volume that we considered for reference. Four patients have been included. They had {sup 18}F-F.D.G. PET scan followed by complete tumoral removal surgery. Specific histological procedure allowed to define complete size of the tumor in re expanded lung. Comparatively to pathology, the volumes obtained using I{sub max} 40 and I{sub max} 50 are all underestimated. The volumes defined by Black's et al. method are under evaluated for the two largest tumours (15.8% to 22%) and overestimated for the two smallest ones (17.9 to 82.9%). Nestle's et al. method, using {beta} = 0.15, correctly estimates two tumor volumes over 2 cm, but overestimates the two small tumors (79.6 to 124%). Finally, the corrected Nestle's et al. formula (using {beta} = 0.264) overestimates three tumours. Volumes defined on CT scan by radio physicist are correct for one lesion, underestimated for one and overestimated for two other ones (44 and 179.5%). Nestle

  1. Grout to meet physical and chemical requirements for closure at Hanford grout vaults. Final report

    International Nuclear Information System (INIS)

    1994-01-01

    The US Army Engineer Waterways Experiment Station (WES) developed a grout based on portland cement, Class F fly ash, and bentonite clay, for the Hanford Grout Vault Program. The purpose of this grout was to fill the void between a wasteform containing 106-AN waste and the vault cover blocks. Following a successful grout development program, heat output, volume change, and compressive strength were monitored with time in simulated repository conditions and in full-depth physical models. This research indicated that the cold-cap grout could achieve and maintain adequate volume stability and other required physical properties in the internal environment of a sealed vault. To determine if contact with 106-AN liquid waste would cause chemical deterioration of the cold-cap grout, cured specimens were immersed in simulated waste. Over a period of 21 days at 150 F, specimens increased in mass without significant changes in volume. X-ray diffraction of reacted specimens revealed crystallization of sodium aluminum silicate hydrate. Scanning electron microscopy used with X-ray fluorescence showed that clusters if this phase had formed in grout pores, increasing grout density and decreasing its effective porosity. Physical and chemical tests collectively indicate a sealing component. However, the Hanford Grout Vault Program was cancelled before completion of this research. This report summarizes close-out Waterways Experiment Station when the Program was cancelled

  2. Validation study of an interpolation method for calculating whole lung volumes and masses from reduced numbers of CT-images in ponies.

    Science.gov (United States)

    Reich, H; Moens, Y; Braun, C; Kneissl, S; Noreikat, K; Reske, A

    2014-12-01

    Quantitative computer tomographic analysis (qCTA) is an accurate but time intensive method used to quantify volume, mass and aeration of the lungs. The aim of this study was to validate a time efficient interpolation technique for application of qCTA in ponies. Forty-one thoracic computer tomographic (CT) scans obtained from eight anaesthetised ponies positioned in dorsal recumbency were included. Total lung volume and mass and their distribution into four compartments (non-aerated, poorly aerated, normally aerated and hyperaerated; defined based on the attenuation in Hounsfield Units) were determined for the entire lung from all 5 mm thick CT-images, 59 (55-66) per animal. An interpolation technique validated for use in humans was then applied to calculate qCTA results for lung volumes and masses from only 10, 12, and 14 selected CT-images per scan. The time required for both procedures was recorded. Results were compared statistically using the Bland-Altman approach. The bias ± 2 SD for total lung volume calculated from interpolation of 10, 12, and 14 CT-images was -1.2 ± 5.8%, 0.1 ± 3.5%, and 0.0 ± 2.5%, respectively. The corresponding results for total lung mass were -1.1 ± 5.9%, 0.0 ± 3.5%, and 0.0 ± 3.0%. The average time for analysis of one thoracic CT-scan using the interpolation method was 1.5-2 h compared to 8 h for analysis of all images of one complete thoracic CT-scan. The calculation of pulmonary qCTA data by interpolation from 12 CT-images was applicable for equine lung CT-scans and reduced the time required for analysis by 75%. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Requirements for AMLCDs in U.S. military applications

    Science.gov (United States)

    Hopper, Darrel G.; Desjardins, Daniel D.

    1995-06-01

    Flat panel displays are fast becoming a significant source of more defense for less money. Military instruments have begun to use color active matrix liquid crystal displays (AMLCDs). This is the beginning of a significant transition from electromechanical, CRT. dichroic LCD, and electroluminescent display designs to the AMLCD designs. We have the opportunity with this new technology to establish common products capable of meeting user requirements for sunlight-readable, color and grayscale capable, high-sharpness high-pixel count, flat panel displays for military applications. The Wright Laboratory is leading the development of recommended best practice, draft guidance standard, and performance specifications for this new generation, the flat panel cockpit display generation, of display modules based on requirements for U.S. military aircraft and ground combat human system interfaces. These requirements are similar in many regards to those in both the civil aviation and automotive industries; accordingly, commonality with these civil applications is incorporated where possible, against the requirements for military combat applications. The performance requirement may be achieved by two approaches: militarization of displays made to low requirements of a large volume civil products manufacturer like Sharp or integration of displays made to high requirements by a niche market commercial vendor, like Optical Imaging Systems, Litton Systems Limited, ImageQuest Inc., and Planar Advanced Inc. teamed with Xerox PARC and Standish Industries. [Note that the niche market companies listed are commercial off-the shelf vendors, albeit for high requirement low volume customers.] Given that the performance specifications can be met for a particular military product by either approach, the choice is based on life cycle cost and a thin analysis based on initial costs alone is not acceptable as it ignores the fact that military product life cycles and procurements are 20-60 years

  4. Image-guided radiotherapy of bladder cancer: bladder volume variation and its relation to margins

    DEFF Research Database (Denmark)

    Muren, Ludvig; Redpath, Anthony Thomas; Lord, Hannah

    2007-01-01

    : The correlation between the relative bladder volume (RBV, defined as repeat scan volume/planning scan volume) and the margins required to account for internal motion was first studied using a series of 20 bladder cancer patients with weekly repeat CT scanning during treatment. Both conformal RT (CRT) and IGRT......BACKGROUND AND PURPOSE: To control and account for bladder motion is a major challenge in radiotherapy (RT) of bladder cancer. This study investigates the relation between bladder volume variation and margins in conformal and image-guided RT (IGRT) for this disease. MATERIALS AND METHODS...... these patients were given fluid intake restrictions on alternating weeks during treatment. RESULTS: IGRT gave the strongest correlation between the RBV and margin size (R(2)=0.75; p10mm were required in only 1% of the situations when the RBV1, whereas isotropic margins >10...

  5. Viability Assessment Volume 2

    International Nuclear Information System (INIS)

    1998-01-01

    This volume describes the major design features of the Monitored Geologic Repository. This document is not intended to provide an exhaustive, detailed description of the repository design. Rather, this document summarizes the major systems and primary elements of the design that are radiologically significant, and references the specific technical documents and design analyses wherein the details can be found. Not all portions of the design are at the same level of completeness. Highest priority has been given to assigning resources to advance the design of the Monitored Geologic Repository features that are important to radiological safety and/or waste isolation and for which there is no NRC licensing precedent. Those features that are important to radiological safety and/or waste isolation, but for which there is an NRC precedent, receive second priority. Systems and features that have no impact on radiological safety or waste isolation receive the lowest priority. This prioritization process, referred to as binning, is discussed in more detail in Section 2.3. Not every subject discussed in this volume is given equal treatment with regard to the level of detail provided. For example, less detail is provided for the surface facility design than for the subsurface and waste package designs. This different level of detail is intentional. Greater detail is provided for those functions, structures, systems, and components that play key roles with regard to protecting radiological health and safety and that are not common to existing nuclear facilities already licensed by NRC. A number of radiological subjects are not addressed in the VA, (e.g., environmental qualification of equipment). Environmental qualification of equipment and other radiological safety considerations will be addressed in the LA. Non-radiological safety considerations such as silica dust control and other occupational safety considerations are considered equally important but are not addressed in

  6. The vanishing volume of D = 4 superspace

    Energy Technology Data Exchange (ETDEWEB)

    Bossard, Guillaume, E-mail: bossard@cpht.polytechnique.f [Ecole Polytechnique (CNRS), Palaiseau Cedex (France). Centre de Physique Theorique; Howe, P.S., E-mail: paul.howe@kcl.ac.u [University of London (United Kingdom). King' s College. Dept. of Mathematics; Stelle, K.S., E-mail: stelle@imperial.ac.u [Imperial College London (United Kingdom). Theoretical Physics Group; Vanhove, Pierre, E-mail: pierre.vanhove@cea.f [University of California, Santa Barbara, CA (United States). Kavli Inst. for Theoretical Physics

    2011-07-01

    The volume of on-shell D = 4, N = 8 superspace is shown to vanish. Despite this, it is shown that there is a fully supersymmetric and duality-invariant candidate {nabla}{sup 8}R{sup 4} counterterm corresponding to an anticipated seven-loop logarithmic divergence in D = 4. We construct this counterterm explicitly and also give the complete nonlinear extension of the 1=8-BPS {nabla}{sup 6}R{sup 4} invariant. Similar results are derived for N = 4; 5 and 6. (author)

  7. Spacelab Level 4 Programmatic Implementation Assessment Study. Volume 2: Ground Processing requirements

    Science.gov (United States)

    1978-01-01

    Alternate ground processing options are summarized, including installation and test requirements for payloads, space processing, combined astronomy, and life sciences. The level 4 integration resource requirements are also reviewed for: personnel, temporary relocation, transportation, ground support equipment, and Spacelab flight hardware.

  8. Site Environmental Report for 2005 Volume I and Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Ruggieri, Michael

    2006-07-07

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1A, ''Environment, Safety, and Health Reporting''. The ''Site Environmental Report for 2005'' summarizes Berkeley Lab's environmental management performance, presents environmental monitoring results, and describes significant programs for calendar year 2005. (Throughout this report, Ernest Orlando Lawrence Berkeley National Laboratory is referred to as ''Berkeley Lab'', ''the Laboratory'', ''Lawrence Berkeley National Laboratory'', and ''LBNL''.) The report is separated into two volumes. Volume I contains an overview of the Laboratory, the status of environmental programs, and summarized results from surveillance and monitoring activities. This year's Volume I text body is organized into an executive summary followed by six chapters. The report's structure has been reorganized this year, and it now includes a chapter devoted to environmental management system topics. Volume II contains individual data results from surveillance and monitoring activities. The ''Site Environmental Report'' is distributed by releasing it on the Web from the Berkeley Lab Environmental Services Group (ESG) home page, which is located at http://www.lbl.gov/ehs/esg/. Many of the documents cited in this report also are accessible from the ESG Web page. CD and printed copies of this Site Environmental Report are available upon request. The report follows the Laboratory's policy of using the International System of Units (SI), also known as the metric system of measurements. Whenever possible, results are also reported using the more conventional (non-SI) system of measurements, because the non-SI system is referenced by several current

  9. Automatic definition of targeted biological volumes for the radiotherapy applications

    International Nuclear Information System (INIS)

    Hatt, M.; Visvikis, D.; Cheze-Le-Rest, C.; Pradier, O.

    2009-01-01

    The proposed method: Fuzzy locally adaptive Bayesian (F.L.A.B.) showed its reliability and its precision on very complete collection of realistic simulated and real data. Its use in the context of radiotherapy allows to consider easily the studies implementation and scenari of dose painting or dose escalation, including in complex cases of heterogenous fixations. It is conceivable to apply F.L.A.B. on PET images with F.M.I.S.O. ( 18 F fluoro misonidazole) or F.L.T. (fluoro-L-thymidine) to complete the definition of the biological target volume. (N.C.)

  10. Water-vapor pressure control in a volume

    Science.gov (United States)

    Scialdone, J. J.

    1978-01-01

    The variation with time of the partial pressure of water in a volume that has openings to the outside environment and includes vapor sources was evaluated as a function of the purging flow and its vapor content. Experimental tests to estimate the diffusion of ambient humidity through openings and to validate calculated results were included. The purging flows required to produce and maintain a certain humidity in shipping containers, storage rooms, and clean rooms can be estimated with the relationship developed here. These purging flows are necessary to prevent the contamination, degradation, and other effects of water vapor on the systems inside these volumes.

  11. The influence of management and construction methods in the repair costs of Spain’s low-volume road network

    Directory of Open Access Journals (Sweden)

    Eutiquio Gallego

    2016-06-01

    Full Text Available This paper describes the entire process of the implementation of the Spanish low volume road network, including the design criteria, the construction techniques and the management policies during all the periods. The current situation of low volume roads in Spain was analyzed with respect to the legal framework and their actual condition. In addition, the budget required for the repair of 41 low volume roads throughout Spain was calculated in order to statistically analyze the influence of the pavement materials and the period of construction. The main conclusions were that low volume roads constructed during the 1970´s are currently those in the best state of repair and those requiring the lower repair costs, even lower than those constructed after 1980´s. In addition, low volume roads constructed with higher quality materials and using standardized techniques required five times lower repair costs than those made of lower quality materials.

  12. Radiologic measurement of extraocular muscle volumes in patients with Graves' orbitopathy: a review and guideline.

    Science.gov (United States)

    Bijlsma, Ward R; Mourits, Maarten Ph

    2006-06-01

    To evaluate and compare techniques for extraocular muscle (EOM) volume measurement and to provide guidelines for future measurements. Systematic review. Existing techniques used to measure extraocular muscle volumes on radiologic scans can be divided into manual outlining, computer assisted and automated segmentation. Both computed tomography (CT) and magnetic resonance (MR) image datasets can be used. On CT scans, one best measures muscle volume using region grow segmentation, accepting an overestimation of true volume by inevitable inclusion of non-muscular tissue. On high resolution MRI scans, single muscles can be outlined manually, but measurements include only part of the muscle due to poor tissue contrast at the orbital apex. Measurement errors can be reduced 3.5% by exact horizontal repositioning. A measured volume change of at least 6-17% is required to demonstrate a significant difference. Currently the best choice for EOM volume measurements on CT images is computer assisted grey value segmentation and on MRI images is manual outlining of individual muscles. Because of the time required and the complexity of the measurements, present EOM volume measurement is as yet only suitable for research purposes.

  13. Ground-water monitoring compliance projects for Hanford Site facilities: Progress report, January 1-March 31, 1988: Volume 3, Appendix A

    International Nuclear Information System (INIS)

    1988-05-01

    This appendix is one of nine volumes, and presents data describing wells completed at the Hanford Site during the fourth quarter of calendar year 1987 (October through December). The data in this volume of Appendix A cover the following wells: 299-E32-2; 299-E32-3; 299-E32-4; 299-E33-28; 299-E33-29. The data are presented in the following order: Well Completion Report/Title III Inspection List, Inspection Plan, As-Built Diagram, Logging Charts, and Drill Logs

  14. Glacier Volume Change Estimation Using Time Series of Improved Aster Dems

    Science.gov (United States)

    Girod, Luc; Nuth, Christopher; Kääb, Andreas

    2016-06-01

    Volume change data is critical to the understanding of glacier response to climate change. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) system embarked on the Terra (EOS AM-1) satellite has been a unique source of systematic stereoscopic images covering the whole globe at 15m resolution and at a consistent quality for over 15 years. While satellite stereo sensors with significantly improved radiometric and spatial resolution are available to date, the potential of ASTER data lies in its long consistent time series that is unrivaled, though not fully exploited for change analysis due to lack of data accuracy and precision. Here, we developed an improved method for ASTER DEM generation and implemented it in the open source photogrammetric library and software suite MicMac. The method relies on the computation of a rational polynomial coefficients (RPC) model and the detection and correction of cross-track sensor jitter in order to compute DEMs. ASTER data are strongly affected by attitude jitter, mainly of approximately 4 km and 30 km wavelength, and improving the generation of ASTER DEMs requires removal of this effect. Our sensor modeling does not require ground control points and allows thus potentially for the automatic processing of large data volumes. As a proof of concept, we chose a set of glaciers with reference DEMs available to assess the quality of our measurements. We use time series of ASTER scenes from which we extracted DEMs with a ground sampling distance of 15m. Our method directly measures and accounts for the cross-track component of jitter so that the resulting DEMs are not contaminated by this process. Since the along-track component of jitter has the same direction as the stereo parallaxes, the two cannot be separated and the elevations extracted are thus contaminated by along-track jitter. Initial tests reveal no clear relation between the cross-track and along-track components so that the latter seems not to be

  15. Assessment methodology for new cooling lakes. Volume 3. Limnological and fisheries data and bibliography. Final report

    International Nuclear Information System (INIS)

    1981-10-01

    This is the data volume of the report entitled Assessment Methodology for New Cooling Lakes. Limnological and fisheries data were compiled in this volume for potential users in the utility industry. Published papers, reports, other written information, computer files, and direct contracts were used to compile a matrix of information. This volume presents data and the bibliographic sources of the power plant and geographical, limnological, and fisheries information for 181 lakes and reservoirs, of which 134 were used for cooling purposes. Data for 65 lakes were completed with respect to the limnology and fisheries parameters so that complete statistical analysis could be performed. Of these 65 lakes, 42 are used for cooling. Tables in this report contain data arranged by utility, power plant, limnology, water quality, morphoedaphic, and fishery categories. The data in the tables are keyed to a lake code. The references for the data shown are keyed to a numerical listing of the bibliography. Author, state, lake, and subject indexes facilitate searching for bibliographic information

  16. GENII: The Hanford Environmental Radiation Dosimetry Software System: Volume 1, Conceptual representation

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.; Ramsdell, J.V.

    1988-12-01

    The Hanford Environmental Dosimetry Upgrade Project was undertaken to incorporate the internal dosimetry models recommended by the International Commission on Radiological Protection (ICRP) in updated versions of the environmental pathway analysis models used at Hanford. The resulting second generation of Hanford environmental dosimetry computer codes is compiled in the Hanford Environmental Dosimetry System (Generation II, or GENII). The purpose of this coupled system of computer codes is to analyze environmental contamination resulting from acute or chronic releases to, or initial contamination of, air, water, or soil. This is accomplished by calculating radiation doses to individuals or populations. GENII is described in three volumes of documentation. The first volume describes the theoretical considerations of the system. The second volume is a Users' Manual, providing code structure, users' instructions, required system configurations, and QA-related topics. The third volume is a Code Maintenance Manual for the user who requires knowledge of code detail. It includes code logic diagrams, global dictionary, worksheets, example hand calculations, and listings of the code and its associated data libraries. 72 refs., 15 figs., 34 tabs.

  17. GENII: The Hanford Environmental Radiation Dosimetry Software System: Volume 1, Conceptual representation

    International Nuclear Information System (INIS)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.; Ramsdell, J.V.

    1988-12-01

    The Hanford Environmental Dosimetry Upgrade Project was undertaken to incorporate the internal dosimetry models recommended by the International Commission on Radiological Protection (ICRP) in updated versions of the environmental pathway analysis models used at Hanford. The resulting second generation of Hanford environmental dosimetry computer codes is compiled in the Hanford Environmental Dosimetry System (Generation II, or GENII). The purpose of this coupled system of computer codes is to analyze environmental contamination resulting from acute or chronic releases to, or initial contamination of, air, water, or soil. This is accomplished by calculating radiation doses to individuals or populations. GENII is described in three volumes of documentation. The first volume describes the theoretical considerations of the system. The second volume is a Users' Manual, providing code structure, users' instructions, required system configurations, and QA-related topics. The third volume is a Code Maintenance Manual for the user who requires knowledge of code detail. It includes code logic diagrams, global dictionary, worksheets, example hand calculations, and listings of the code and its associated data libraries. 72 refs., 15 figs., 34 tabs

  18. Detector Requirements to Curb Nuclear Smuggling

    International Nuclear Information System (INIS)

    Erickson, S A

    2001-01-01

    The problem of stopping nuclear smuggling of terrorist nuclear devices is a complex one, owing to the variety of pathways by which such a device can be transported. To fashion new detection systems that improve the chances of detecting such a device, it is important to know the various requirements and conditions that would be imposed on them by both the types of devices that might be smuggled and by the requirement that it not overly interfere with the transportation of legitimate goods. Requirements vary greatly from low-volume border crossings to high-volume industrial container ports, and the design of systems for them is likely to be quite different. There is also a further need to detect these devices if they are brought into a country via illicit routes, i.e., those which do not pass through customs posts, but travel overland though open space or to a smaller, unguarded airport or seaport. This paper describes some generic uses of detectors, how they need to be integrated into customs or other law enforcement systems, and what the specifications for such detectors might be

  19. Transaction-based building controls framework, Volume 2: Platform descriptive model and requirements

    Energy Technology Data Exchange (ETDEWEB)

    Akyol, Bora A. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Haack, Jereme N. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Carpenter, Brandon J. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Katipamula, Srinivas [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Lutes, Robert G. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Hernandez, George [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2015-07-31

    Transaction-based Building Controls (TBC) offer a control systems platform that provides an agent execution environment that meets the growing requirements for security, resource utilization, and reliability. This report outlines the requirements for a platform to meet these needs and describes an illustrative/exemplary implementation.

  20. Volume 1: Survey of Available Information in Support of the Energy-Water Bandwidth Study of Desalination Systems

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Prakash [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Aghajanzadeh, Arian [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sheaffer, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Morrow, William R. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Brueske, Sabine [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Dollinger, Caroline [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Price, Kevin [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sarker, Prateeti [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ward, Nicholas [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Cresko, Joe [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2016-10-01

    The U.S. Department of Energy (DOE) has set a goal to reduce the cost of seawater desalination systems to $0.50/ cubic meter (m3) through the development of technology pathways to reduce energy, capital, operating, soft, and system integration costs.1 In support of this goal and to evaluate the technology pathways to lower the energy and carbon intensity of desalination while also reducing the total water cost, DOE is undertaking a comprehensive study of the energy consumption and carbon dioxide (CO2) emissions for desalination technologies and systems. This study is being undertaken in two phases. Phase 1, Survey of Available Information in Support of the Energy-Water Bandwidth Study of Desalination Systems, collected the background information that will underpin Phase 2, the Energy Water Bandwidth Study for Desalination Systems. This report (Volume 1) summarizes the results from Phase 1. The results from Phase 2 will be summarized in Volume 2: Energy Water Bandwidth Study for Desalination Systems (Volume 2). The analysis effort for Phase 2 will utilize similar methods as other industry-specific Energy Bandwidth Studies developed by DOE,2 which has provided a framework to evaluate and compare energy savings potentials within and across manufacturing sectors at the macroscale. Volume 2 will assess the current state of desalination energy intensity and reduction potential through the use of advanced and emerging technologies. For the purpose of both phases of study, energy intensity is defined as the amount of energy required per unit of product water output (for example, kilowatt-hours per cubic meter of water produced). These studies will expand the scope of previous sectorial bandwidth studies by also evaluating CO2 intensity and reduction opportunities and informing a techno-economic analysis of desalination systems. Volume 2 is expected to be completed in 2017.

  1. Blind RRT: A probabilistically complete distributed RRT

    KAUST Repository

    Rodriguez, Cesar; Denny, Jory; Jacobs, Sam Ade; Thomas, Shawna; Amato, Nancy M.

    2013-01-01

    Rapidly-Exploring Random Trees (RRTs) have been successful at finding feasible solutions for many types of problems. With motion planning becoming more computationally demanding, we turn to parallel motion planning for efficient solutions. Existing work on distributed RRTs has been limited by the overhead that global communication requires. A recent approach, Radial RRT, demonstrated a scalable algorithm that subdivides the space into regions to increase the computation locality. However, if an obstacle completely blocks RRT growth in a region, the planning space is not covered and is thus not probabilistically complete. We present a new algorithm, Blind RRT, which ignores obstacles during initial growth to efficiently explore the entire space. Because obstacles are ignored, free components of the tree become disconnected and fragmented. Blind RRT merges parts of the tree that have become disconnected from the root. We show how this algorithm can be applied to the Radial RRT framework allowing both scalability and effectiveness in motion planning. This method is a probabilistically complete approach to parallel RRTs. We show that our method not only scales but also overcomes the motion planning limitations that Radial RRT has in a series of difficult motion planning tasks. © 2013 IEEE.

  2. Blind RRT: A probabilistically complete distributed RRT

    KAUST Repository

    Rodriguez, Cesar

    2013-11-01

    Rapidly-Exploring Random Trees (RRTs) have been successful at finding feasible solutions for many types of problems. With motion planning becoming more computationally demanding, we turn to parallel motion planning for efficient solutions. Existing work on distributed RRTs has been limited by the overhead that global communication requires. A recent approach, Radial RRT, demonstrated a scalable algorithm that subdivides the space into regions to increase the computation locality. However, if an obstacle completely blocks RRT growth in a region, the planning space is not covered and is thus not probabilistically complete. We present a new algorithm, Blind RRT, which ignores obstacles during initial growth to efficiently explore the entire space. Because obstacles are ignored, free components of the tree become disconnected and fragmented. Blind RRT merges parts of the tree that have become disconnected from the root. We show how this algorithm can be applied to the Radial RRT framework allowing both scalability and effectiveness in motion planning. This method is a probabilistically complete approach to parallel RRTs. We show that our method not only scales but also overcomes the motion planning limitations that Radial RRT has in a series of difficult motion planning tasks. © 2013 IEEE.

  3. Specifying semantic information on functional requirements

    OpenAIRE

    YAO, WUPING

    2012-01-01

    Requirements engineering is a challenging process in software development projects. Requirements, in general, are documented in natural language. They often have issues related to ambiguity, completeness and consistency. How to improve the quality of requirements documentation remains a classic research topic. This research aims at improving the way of editing and documenting functional requirements. We propose a meta-model to specify the semantic information of functional requirements, and d...

  4. p-topological Cauchy completions

    Directory of Open Access Journals (Sweden)

    J. Wig

    1999-01-01

    Full Text Available The duality between “regular” and “topological” as convergence space properties extends in a natural way to the more general properties “p-regular” and “p-topological.” Since earlier papers have investigated regular, p-regular, and topological Cauchy completions, we hereby initiate a study of p-topological Cauchy completions. A p-topological Cauchy space has a p-topological completion if and only if it is “cushioned,” meaning that each equivalence class of nonconvergent Cauchy filters contains a smallest filter. For a Cauchy space allowing a p-topological completion, it is shown that a certain class of Reed completions preserve the p-topological property, including the Wyler and Kowalsky completions, which are, respectively, the finest and the coarsest p-topological completions. However, not all p-topological completions are Reed completions. Several extension theorems for p-topological completions are obtained. The most interesting of these states that any Cauchy-continuous map between Cauchy spaces allowing p-topological and p′-topological completions, respectively, can always be extended to a θ-continuous map between any p-topological completion of the first space and any p′-topological completion of the second.

  5. Towards high-resolution positron emission tomography for small volumes

    International Nuclear Information System (INIS)

    McKee, B.T.A.

    1982-01-01

    Some arguments are made regarding the medical usefulness of high spatial resolution in positron imaging, even if limited to small imaged volumes. Then the intrinsic limitations to spatial resolution in positron imaging are discussed. The project to build a small-volume, high resolution animal research prototype (SHARP) positron imaging system is described. The components of the system, particularly the detectors, are presented and brief mention is made of data acquisition and image reconstruction methods. Finally, some preliminary imaging results are presented; a pair of isolated point sources and 18 F in the bones of a rabbit. Although the detector system is not fully completed, these first results indicate that the goals of high sensitivity and high resolution (4 mm) have been realized. (Auth.)

  6. The design, development, and test of balloonborne and groundbased lidar systems. Volume 2: Flight test of Atmospheric Balloon Lidar Experiment, ABLE 2

    Science.gov (United States)

    Shepherd, O.; Bucknam, R. D.; Hurd, A. G.; Sheehan, W. H.

    1991-06-01

    This is Volume 3 of a three volume final report on the design, development, and test of balloonborne and groundbased lidar systems. Volume 1 describes the design and fabrication of a balloonborne CO2 coherent payload to measure the 10.6 micrometers backscatter from atmospheric aerosols as a function of altitude. Volume 2 describes the Aug. 1987 flight test of Atmospheric Balloonborne Lidar Experiment, ABLE 2. In this volume we describe groundbased lidar development and measurements. A design was developed for installation of the ABLE lidar in the GL rooftop dome. A transportable shed was designed to house the ABLE lidar at the various remote measurement sites. Refurbishment and modification of the ABLE lidar were completed to permit groundbased lidar measurements of clouds and aerosols. Lidar field measurements were made at Ascension Island during SABLE 89. Lidar field measurements were made at Terciera, Azores during GABLE 90. These tasks were successfully completed, and recommendations for further lidar measurements and data analysis were made.

  7. Blood utilization in neonates and infants undergoing cardiac surgery requiring cardiopulmonary bypass.

    Science.gov (United States)

    Wesley, Mark C; Yuki, Koichi; Daaboul, Dima G; Dinardo, James A

    2011-07-01

    Neonates and infants undergoing cardiac surgery with cardiopulmonary bypass are exposed to multiple blood products from different donors. The volume of the bypass circuit is often as large as the patient's total blood volume and asanguineous bypass primes are unusual. As a result, blood products are required for the cardiopulmonary bypass prime and are often used to treat the postbypass dilutional coagulopathy. We review clot formation and strength, cardiopulmonary bypass prime considerations, assessment of postbypass coagulopathy, component therapy use, ultrafiltration techniques, and use of antifibrinolytic medications. A combined approach including techniques to minimize the prime volume, utilization of ultrafiltration, administration of antifibrinolytics during surgery, and the proper treatment of the dilutional coagulopathy can limit the transfusion requirements.

  8. Residual limb fluid volume change and volume accommodation: Relationships to activity and self-report outcomes in people with trans-tibial amputation.

    Science.gov (United States)

    Sanders, Joan E; Youngblood, Robert T; Hafner, Brian J; Ciol, Marcia A; Allyn, Katheryn J; Gardner, David; Cagle, John C; Redd, Christian B; Dietrich, Colin R

    2018-02-01

    Fluctuations in limb volume degrade prosthesis fit and require users to accommodate changes using management strategies, such as donning and doffing prosthetic socks. To examine how activities and self-report outcomes relate to daily changes in residual limb fluid volume and volume accommodation. Standardized, two-part laboratory protocol with an interim observational period. Participants were classified as "accommodators" or "non-accommodators," based on self-report prosthetic sock use. Participants' residual limb fluid volume change was measured using a custom bioimpedance analyzer and a standardized in-laboratory activity protocol. Self-report health outcomes were assessed with the Socket Comfort Score and Prosthesis Evaluation Questionnaire. Activity was monitored while participants left the laboratory for at least 3 h. They then returned to repeat the bioimpedance test protocol. Twenty-nine people were enrolled. Morning-to-afternoon percent limb fluid volume change per hour was not strongly correlated to percent time weight-bearing or to self-report outcomes. As a group, non-accommodators ( n = 15) spent more time with their prosthesis doffed and reported better outcomes than accommodators. Factors other than time weight-bearing may contribute to morning-to-afternoon limb fluid volume changes and reported satisfaction with the prosthesis among trans-tibial prosthesis users. Temporary doffing may be a more effective and satisfying accommodation method than sock addition. Clinical relevance Practitioners should be mindful that daily limb fluid volume change and prosthesis satisfaction are not dictated exclusively by activity. Temporarily doffing the prosthesis may slow daily limb fluid volume loss and should be investigated as an alternative strategy to sock addition.

  9. Target volumes in gastric cancer radiation therapy; Les volumes-cibles de la radiotherapie des adenocarcinomes gastriques

    Energy Technology Data Exchange (ETDEWEB)

    Caudry, M.; Maire, J.P. [Hopital Saint Andre, Service de Cancerologie, 33 - Bordeaux (France); Ratoanina, J.L.; Escarmant, P. [Hopital Clarac, Service de Radiotherapie et de Cancerologie, 97 - Fort de France (France)

    2001-10-01

    The spread of gastric adenocarcinoma may follow three main patterns: hemato-genic, lymphatic and intraperitoneal. A GTV should be considered in preoperative or exclusive radiation therapy. After non-radical surgery, a 'residual GTV' will be defined with the help of the surgeon. The CTV encompasses three intricated volumes. a) A 'tumor bed' volume. After radical surgery, local recurrences appear as frequent as distant metastases. The risk depends upon the depth of parietal invasion and the nodal status. Parietal infiltration may extend beyond macroscopic limits of the tumor, especially in dinitis plastica. Therefore this volume will include: the tumor and the remaining stomach or their 'bed of resection', a part of the transverse colon, the duodenum, the pancreas and the troncus of the portal vein. In postoperative RT, this CTV also includes the jejuno-gastric or jejuno-esophageal anastomosis. b) A peritoneal volume. For practical purposes, two degrees of spread must be considered: (1) contiguous microscopic extension from deeply invasive T3 and T4 tumors, that remain amenable to local sterilization with doses of 45-50 Gy, delivered in a CTV including the peritoneal cavity at the level of the gastric bed, and under the parietal incision; (2) true 'peritoneal carcinomatosis', with widespread seeds, where chemotherapy (systemic or intraperitoneal) is more appropriate. c) A lymphatic volume including the lymph node groups 1 to 16 of the Japanese classification. This volume must encompass the hepatic pedicle and the splenic hilum. In proximal tumors, it is possible to restrict the lover part of the CTV to the lymphatic volume, and therefore to avoid irradiation of large intestinal and renal volumes. In distal and proximal tumors, involvement of resection margins is of poor prognosis -a radiation boost must be delivered at this level. The CTV in tumors of the cardia should encompass the lover part of the thoracic esophagus and the

  10. Quantum theory and questions of reality and completeness

    International Nuclear Information System (INIS)

    Andaas, H.E.; Gjoetterud, O.K.

    1991-10-01

    The authors discuss how the description of a two-particle spin-1/2 system prepared in a singlet state, a product state of definite total spin-projection and a specified mixture relates to the EPR conceptions of reality, locality and completeness and to Jarrets interpretations and representations of these concepts by probability statements. The importance of the state-preparation procedures and their relevance in this context is emphasized. The position of Bell's inequalities is also discussed. It is concluded that the inequalities have a limited power in deciding whether or not a system requires a quantal description, and that making a priori claims on reality and completeness is a too narrow scheme to describe quantal phenomena. 21 refs., 4 figs

  11. Quantum theory and questions of reality and completeness

    International Nuclear Information System (INIS)

    Andaas, H.E.; Gjoetterud, O.K.

    1992-07-01

    The authors discuss how the description of a two-particle spin-1/2 system prepared in a singlet state, a product state of definite total spin-projection and a specified mixture relates to the EPR conceptions of reality, locality and completeness and to Jarrets interpretations and representations of these concepts by probability statements. The importance of the state-preparation procedures and their relevance in this context is emphasized. The position of Bell's inequalities is also discussed. It is concluded that the inequalities have a limited power in deciding whether or not a system requires a quantal decription and that making a priori claims on reality and completeness is a too narrow scheme to describe quantal phenomena. 22 refs. 4 figs

  12. Altitude Acclimatization and Blood Volume: Effects of Exogenous Erythrocyte Volume Expansion

    National Research Council Canada - National Science Library

    Sawka, M

    1996-01-01

    ...: (a) altitude acclimatization effects on erythrocyte volume and plasma volume; (b) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations; (c...

  13. Influence of 5% dextrose volume on amphotericin B deoxycholate preparation.

    Science.gov (United States)

    Sun, Pingping; Chen, Jie; Zhang, Zhihao; Gao, Xiang; Chen, Pan; Li, Shuxia

    2016-04-01

    Preparation of amphotericin B deoxycholate (AmB-d) in different volumes of 5% dextrose (D5W) was studied to investigate a interesting phenomenon that AmB-d was easy to bring pipe blockage when diluted in 500 ml but not in 50 ml. AmB-d (25 mg/vial) in 50 ml, 250 ml or 500 ml D5W was prepared. Fluids were collected before and after infusion, then were assayed by validated high-performance liquid chromatography (HPLC) method. Light obscuration assay was used to detect the particles in transfusions. pH values of different volumes of D5W were all about 3.7, which was lower than the requirement of AmB-d package insert (pH > 4.2). The number of insoluble particles >10 μm/25 μm in 25 mg/500 ml infusions exceeded China Pharmacopoeia limit. Filters in 25 mg/500 ml infusion set were full of AmB-d after dripping slowly for 6 h, and 331.3 ml solution was left in the bottles and only 11.3% of AmB-d could flow out. Whereas the AmB-d infusion consists of 25 mg/50 ml, 25 mg/250 ml and 50 mg/500 ml could meet with China Pharmacopoeia standards, and they flowed out easily and completely. In practice, 25 mg/250 ml and 50 mg/500 ml would be more suitable for clinical use, rather than 25 mg/500 ml. We provided a convenient method for AmB-d preparation. © 2016 Royal Pharmaceutical Society, Journal of Pharmacy and Pharmacology.

  14. OPTIMUM VOLUME OF BANK RESERVE: FORECASTING OF OVERDUE CREDIT INDEBTEDNESS USING COPULA MODELS

    Directory of Open Access Journals (Sweden)

    Kazakova K. A.

    2015-12-01

    Full Text Available The article propose to consider the possibility of RLUF-copulas application for the creation of joint distributions of overdue credit indebtedness ranks with macroeconomic indicators for the purpose of indebtedness forecasting and also for the definition of optimum volumes of reserve requirements for the corresponding losses. In this research the comparative analysis of multivariate distributions of RLUF-copula estimation with such classical copulas, as FGM-copula, Frank's copula and Gauss's copula is made. In the article the method of maximum likelihood is used for receiving estimates of model parameters. In case of RLUF-copula Bayesian estimates of parameters are received using the Metropolis algorithm with random volatility. Forecasting of bank reserve volumes for all received models is executed in the form of random sample generation by the means of the algorithm of acceptance-deviation for the creation of the corresponding sample of joint distribution using the copula density function. As the result of playing of hundred possible scenarios of indebtedness volumes is obtained the 95 % confidence level for the possible volume of credit indebtedness which can fully act as the optimum volume of reserve requirements for the corresponding credit losses.

  15. Next Generation Microbiology Requirements

    Science.gov (United States)

    Ott, C. M.; Oubre, C. M.; Elliott, T. F.; Castro, V. A.; Pierson, D. L.

    2012-01-01

    As humans continue to explore deep into space, microorganisms will travel with them. The primary means to mitigate the risk of infectious disease are a combination of prudent spacecraft design and rigorous operational controls. The effectiveness of these methods are evaluated by microbiological monitoring of spacecraft, food, water, and the crew that is performed preflight, in-flight, and post-flight. Current NASA requirements associated with microbiological monitoring are based on culture-based methodology where microorganisms are grown on a semi-solid growth medium and enumerated. Subsequent identification of the organisms requires specialized labor and large equipment, which historically has been performed on Earth. Requirements that rely strictly on culture-based units limit the use of non-culture based monitoring technology. Specifically, the culture-based "measurement criteria" are Colony Forming Units (CFU, representing the growth of one microorganism at a single location on the agar medium) per a given volume, area, or sample size. As the CFU unit by definition is culture-based, these requirements limit alternative technologies for spaceflight applications. As spaceflight missions such as those to Mars extend further into space, culture-based technology will become difficult to implement due to the (a) limited shelf life of the culture media, (b) mass/volume necessary to carry these consumables, and (c) problems associated with the production of biohazardous material in the habitable volume of the spacecraft. In addition, an extensive amount of new knowledge has been obtained during the Space Shuttle, NASA-Mir, and International Space Station Programs, which gave direction for new or modified microbial control requirements for vehicle design and mission operations. The goal of this task is to develop and recommend a new set of requirements for vehicle design and mission operations, including microbiological monitoring, based upon "lessons learned" and new

  16. FBI fingerprint identification automation study: AIDS 3 evaluation report. Volume 9: Functional requirements

    Science.gov (United States)

    1980-01-01

    The current system and subsystem used by the Identification Division are described. System constraints that dictate the system environment are discussed and boundaries within which solutions must be found are described. The functional requirements were related to the performance requirements. These performance requirements were then related to their applicable subsystems. The flow of data, documents, or other pieces of information from one subsystem to another or from the external world into the identification system is described. Requirements and design standards for a computer based system are presented.

  17. Spacelab user implementation assessment study. (Software requirements analysis). Volume 2: Technical report

    Science.gov (United States)

    1976-01-01

    The engineering analyses and evaluation studies conducted for the Software Requirements Analysis are discussed. Included are the development of the study data base, synthesis of implementation approaches for software required by both mandatory onboard computer services and command/control functions, and identification and implementation of software for ground processing activities.

  18. No-migration variance petition: Draft. Volume 4, Appendices DIF, GAS, GCR (Volume 1)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-31

    The Department of Energy is responsible for the disposition of transuranic (TRU) waste generated by national defense-related activities. Approximately 2.6 million cubic feet of the se waste have been generated and are stored at various facilities across the country. The Waste Isolation Pilot Plant (WIPP), was sited and constructed to meet stringent disposal requirements. In order to permanently dispose of TRU waste, the DOE has elected to petition the US EPA for a variance from the Land Disposal Restrictions of RCRA. This document fulfills the reporting requirements for the petition. This report is volume 4 of the petition which presents details about the transport characteristics across drum filter vents and polymer bags; gas generation reactions and rates during long-term WIPP operation; and geological characterization of the WIPP site.

  19. No-migration variance petition: Draft. Volume 4, Appendices DIF, GAS, GCR (Volume 1)

    International Nuclear Information System (INIS)

    1995-01-01

    The Department of Energy is responsible for the disposition of transuranic (TRU) waste generated by national defense-related activities. Approximately 2.6 million cubic feet of the se waste have been generated and are stored at various facilities across the country. The Waste Isolation Pilot Plant (WIPP), was sited and constructed to meet stringent disposal requirements. In order to permanently dispose of TRU waste, the DOE has elected to petition the US EPA for a variance from the Land Disposal Restrictions of RCRA. This document fulfills the reporting requirements for the petition. This report is volume 4 of the petition which presents details about the transport characteristics across drum filter vents and polymer bags; gas generation reactions and rates during long-term WIPP operation; and geological characterization of the WIPP site

  20. The Role of Amodal Surface Completion in Stereoscopic Transparency

    Science.gov (United States)

    Anderson, Barton L.; Schmid, Alexandra C.

    2012-01-01

    Previous work has shown that the visual system can decompose stereoscopic textures into percepts of inhomogeneous transparency. We investigate whether this form of layered image decomposition is shaped by constraints on amodal surface completion. We report a series of experiments that demonstrate that stereoscopic depth differences are easier to discriminate when the stereo images generate a coherent percept of surface color, than when images require amodally integrating a series of color changes into a coherent surface. Our results provide further evidence for the intimate link between the segmentation processes that occur in conditions of transparency and occlusion, and the interpolation processes involved in the formation of amodally completed surfaces. PMID:23060829

  1. Holomorphic Yukawa couplings for complete intersection Calabi-Yau manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Blesneag, Stefan [Rudolf Peierls Centre for Theoretical Physics, Oxford University,1 Keble Road, Oxford, OX1 3NP (United Kingdom); Buchbinder, Evgeny I. [The University of Western Australia,35 Stirling Highway, Crawley WA 6009 (Australia); Lukas, Andre [Rudolf Peierls Centre for Theoretical Physics, Oxford University,1 Keble Road, Oxford, OX1 3NP (United Kingdom)

    2017-01-27

    We develop methods to compute holomorphic Yukawa couplings for heterotic compactifications on complete intersection Calabi-Yau manifolds, generalising results of an earlier paper for Calabi-Yau hypersurfaces. Our methods are based on constructing the required bundle-valued forms explicitly and evaluating the relevant integrals over the projective ambient space. We also show how our approach relates to an earlier, algebraic one to calculate the holomorphic Yukawa couplings. A vanishing theorem, which we prove, implies that certain Yukawa couplings allowed by low-energy symmetries are zero due to topological reasons. To illustrate our methods, we calculate Yukawa couplings for SU(5)-based standard models on a co-dimension two complete intersection manifold.

  2. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed

    DEFF Research Database (Denmark)

    Posthuma, Daniëlle; Baare, Wim F.C.; Hulshoff Pol, Hilleke E.

    2003-01-01

    We recently showed that the correlation of gray and white matter volume with full scale IQ and the Working Memory dimension are completely mediated by common genetic factors (Posthuma et al., 2002). Here we examine whether the other WAIS III dimensions (Verbal Comprehension, Perceptual Organization...... to Working Memory capacity (r = 0.27). This phenotypic correlation is completely due to a common underlying genetic factor. Processing Speed was genetically related to white matter volume (r(g) = 0.39). Perceptual Organization was both genetically (r(g) = 0.39) and environmentally (r(e) = -0.71) related...

  3. Interactive Dynamic Volume Illumination with Refraction and Caustics.

    Science.gov (United States)

    Magnus, Jens G; Bruckner, Stefan

    2018-01-01

    In recent years, significant progress has been made in developing high-quality interactive methods for realistic volume illumination. However, refraction - despite being an important aspect of light propagation in participating media - has so far only received little attention. In this paper, we present a novel approach for refractive volume illumination including caustics capable of interactive frame rates. By interleaving light and viewing ray propagation, our technique avoids memory-intensive storage of illumination information and does not require any precomputation. It is fully dynamic and all parameters such as light position and transfer function can be modified interactively without a performance penalty.

  4. Validity and reliability of a novel 3D scanner for assessment of the shape and volume of amputees' residual limb models.

    Directory of Open Access Journals (Sweden)

    Elena Seminati

    Full Text Available Objective assessment methods to monitor residual limb volume following lower-limb amputation are required to enhance practitioner-led prosthetic fitting. Computer aided systems, including 3D scanners, present numerous advantages and the recent Artec Eva scanner, based on laser free technology, could potentially be an effective solution for monitoring residual limb volumes.The aim of this study was to assess the validity and reliability of the Artec Eva scanner (practical measurement against a high precision laser 3D scanner (criterion measurement for the determination of residual limb model shape and volume.Three observers completed three repeat assessments of ten residual limb models, using both the scanners. Validity of the Artec Eva scanner was assessed (mean percentage error <2% and Bland-Altman statistics were adopted to assess the agreement between the two scanners. Intra and inter-rater reliability (repeatability coefficient <5% of the Artec Eva scanner was calculated for measuring indices of residual limb model volume and shape (i.e. residual limb cross sectional areas and perimeters.Residual limb model volumes ranged from 885 to 4399 ml. Mean percentage error of the Artec Eva scanner (validity was 1.4% of the criterion volumes. Correlation coefficients between the Artec Eva and the Romer determined variables were higher than 0.9. Volume intra-rater and inter-rater reliability coefficients were 0.5% and 0.7%, respectively. Shape percentage maximal error was 2% at the distal end of the residual limb, with intra-rater reliability coefficients presenting the lowest errors (0.2%, both for cross sectional areas and perimeters of the residual limb models.The Artec Eva scanner is a valid and reliable method for assessing residual limb model shapes and volumes. While the method needs to be tested on human residual limbs and the results compared with the current system used in clinical practice, it has the potential to quantify shape and volume

  5. Acoustic Leak Detection Requirements for a SFR Steam Generator Protection

    International Nuclear Information System (INIS)

    Kim, Tae-Joon; Jeong, Ji-Young; Oeh, Jae-Hyuk; Kim, Jong-Man; Kim, Byung-Ho; Yughay, Valery S.

    2008-01-01

    A large volume of fast reactor research has been executed in Russia, Japan, France, India and the United Kingdom. At present, an unique fast reactor named BN- 600 is operating in Russia. Also, the operation of research reactors such as Phenix (France), JOYO (Japan), BOR-60 (Russia) and FBTR (India) proceeds. The last project to be completed was the reactor Monju (Japan) which is now stopped. In addition activities for the development of fast reactors are being conducted in China, India, and South Korea. Fast reactors are a choice for the subsequent nuclear power generation in Korea, and their increased safety is one of the basic requirements. The basis for a tightening of the requirements on safety is the emergencies in NPPs in Russia, USA, France, Japan and other countries. These emergencies testify that the existing monitoring systems do not fully provide a well-timed detection of the distresses arising in a NPP, because of a poor sensitivity and response, thus the necessity for a better diagnostic system is obvious. In accordance with the USA GNEP initiative in Obninsk, Russia, 2007 the main efforts should be directed toward a sodium-water steam generator safety increase due to improvement of the hydrogen monitoring system and the acoustic leak detection system

  6. On-Line Monitoring of Instrument Channel Performance: Volume 3: Applications to Nuclear Power Plant Technical Specification Instrumentation

    International Nuclear Information System (INIS)

    Davis, E.; Rasmussen, B.

    2004-01-01

    This report is a guide for a technical specification change submittal and subsequent implementation of on-line monitoring for safety-related applications. This report is the third in a three-volume set. Volume 1, ''Guidelines for Model Development and Implementation'', presents the various tasks that must be completed to prepare models for and to implement an on-line monitoring system

  7. M10.3.1: LHC crab cavity specifications completed

    CERN Document Server

    Ciapala, E

    2010-01-01

    • The starting point of Sub-task 1 is to determine the full LHC system requirements for the crab cavity system. This milestone concerns completion of basic specifications for the crab cavity system. This comprises the beam requirements, the cavity impedance constraints, the operating conditions and constraints, the layout and integration constraints in LHC and very importantly machine protection issues. The specifications of the cavity itself and its ancillaries follow from these system requirements and on the technology chosen for the cavity design. • The beam requirements result from the known parameters of the LHC upgrade lattice and the expected LHC beam parameters at ultimate bunch intensity. There are boundary conditions imposed by certain beam parameters such as the bunch length and intensity and by the machine layout, mainly the available beam pipe separations at the proposed cavity positions. Requirements on RF noise and stability are tight, to avoid emittance blow-up. Machine protection issues a...

  8. Evaluation of maximum voided volume in Korean children by use of a 48-h frequency volume chart.

    Science.gov (United States)

    Kim, Sun-Ouck; Kim, Kyung Do; Kim, Young Sig; Kim, Jun Mo; Moon, Du Geon; Park, Sungchan; Lee, Sang Don; Chung, Jae Min; Cho, Won Yeol

    2012-08-01

    Study Type - Diagnostic (validating cohort). Level of Evidence 2a. What's known on the subject? and What does the study add? The relationship between the maximum voided volume followed a linear curve. The formula presented, bladder capacity (mL) = 12 ×[age (years) + 11], is thought to be a reasonable one for Korean children. Korean children have a smaller bladder capacity than that reported in previous Western studies. • To develop practical guidelines for the prediction of normal bladder capacity in Korean children measured by a frequency volume chart (FVC), maximum voided volume (MVV) is an important factor in the diagnosis of children with abnormal voiding function. • In all, 298 children, aged 3-13 years, with no history of voiding disorders volunteered for the study. The MVV was determined in 219 subjects by use of a completely recorded FVC. • Linear regression analysis was used to define the exact relationship between age and bladder capacity. An approximate formula related age to bladder capacity as follows: bladder capacity (mL) = 12 ×[age (years) + 11]. • The relationship between the MVV measured by a FVC by age (3-13 years) of Korean children followed a linear curve. • When applied to normal voiding patterns, the formula presented appears to be a reasonable one for Korean children. © 2011 BJU INTERNATIONAL.

  9. Completed suicides and self-harm in Malaysia: a systematic review.

    Science.gov (United States)

    Armitage, Christopher J; Panagioti, Maria; Abdul Rahim, Wirda; Rowe, Richard; O'Connor, Rory C

    2015-01-01

    Most of the research into suicide and self-harm has been conducted in the United States and Europe, yet the volume of research does not reflect the distribution of suicide globally, with Asia accounting for up to 60% of all suicides. The present study systematically reviews the literature to assess the prevalence and correlates of suicidal acts in Malaysia in Southeast Asia. Five relevant databases were searched from inception up to February 2014, and a narrative synthesis of the results from the included studies was performed. Studies were eligible for inclusion if they were correlational survey research and archival/observational research describing self-harm and suicide. Outcomes included completed suicides and self-harm including suicide attempts and self-poisoning, suicide plans and suicidal ideation. In total, 39 studies met the inclusion criteria. The principal findings were that the prevalence of suicide in Malaysia is approximately 6-8 per 100,000 population per year and that there is an excess of suicide among men, people younger than 40 years and the Indian minority group. The past-month prevalence rates of suicidal ideation, plans and attempts are 1.7, 0.9% and 0.5%, respectively, whereas the past-year prevalence rates of suicidal ideation range between 6% and 8%. The present research marks a first step towards understanding the prevalence and correlates of suicide and self-harm in Malaysia. However, the heterogeneity of the included studies was high. Further research into the antecedents, consequences and interventions for suicide and self-harm in the Malaysian context is required. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. High tidal volume decreases adult respiratory distress syndrome, atelectasis, and ventilator days compared with low tidal volume in pediatric burned patients with inhalation injury.

    Science.gov (United States)

    Sousse, Linda E; Herndon, David N; Andersen, Clark R; Ali, Arham; Benjamin, Nicole C; Granchi, Thomas; Suman, Oscar E; Mlcak, Ronald P

    2015-04-01

    Inhalation injury, which is among the causes of acute lung injury and acute respiratory distress syndrome (ARDS), continues to represent a significant source of mortality in burned patients. Inhalation injury often requires mechanical ventilation, but the ideal tidal volume strategy is not clearly defined in burned pediatric patients. The aim of this study was to determine the effects of low and high tidal volume on the number of ventilator days, ventilation pressures, and incidence of atelectasis, pneumonia, and ARDS in pediatric burned patients with inhalation injury within 1 year post burn injury. From 1986 to 2014, inhalation injury was diagnosed by bronchoscopy in pediatric burned patients (n = 932). Patients were divided into 3 groups: unventilated (n = 241), high tidal volume (HTV, 15 ± 3 mL/kg, n = 190), and low tidal volume (LTV, 9 ± 3 mL/kg, n = 501). High tidal volume was associated with significantly decreased ventilator days (p tidal volume significantly decreases ventilator days and the incidence of both atelectasis and ARDS compared with low tidal volume in pediatric burned patients with inhalation injury. Therefore, the use of HTV may interrupt sequences leading to lung injury in our patient population. Copyright © 2015 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  11. Perceived Stress Is Differentially Related to Hippocampal Subfield Volumes among Older Adults.

    Directory of Open Access Journals (Sweden)

    Molly E Zimmerman

    Full Text Available Chronic exposure to stress has been shown to impact a wide range of health-related outcomes in older adults. Despite extensive animal literature revealing deleterious effects of biological markers of stress on the dentate gyrus subfield of the hippocampus, links between hippocampal subfields and psychological stress have not been studied in humans. This study examined the relationship between perceived stress and hippocampal subfield volumes among racially/ethnically diverse older adults.Between July 2011 and March 2014, 116 nondemented participants were consecutively drawn from the Einstein Aging Study, an ongoing community-based sample of individuals over the age of 70 residing in Bronx, New York. All participants completed the Perceived Stress Scale, Geriatric Depression Scale, and underwent 3.0 T MRI. FreeSurfer was used to derive total hippocampal volume, hippocampal subfield volumes (CA1, CA2/CA3, CA4/Dentate Gyrus (CA4/DG, and subiculum, entorhinal cortex volume, whole brain volume, and total intracranial volume.Linear regression analyses revealed that higher levels of perceived stress were associated with smaller total hippocampal volume (β = -0.20, t = -2.40, p = 0.02, smaller CA2/CA3 volumes (β = -0.18, t = -2.24, p = 0.03 and smaller CA4/DG volumes (β = -0.19, t = -2.28, p = 0.03 after controlling for total intracranial volume, age, gender, and race. These findings remained unchanged after removal of individuals with clinically significant symptoms of depression.Our findings provide evidence of a relationship between a direct indicator of psychological stress and specific hippocampal subfield volumes in elderly individuals. These results highlight the importance of clinical screening for chronic stress in otherwise healthy older adults.

  12. Graphical User Interfaces for Volume Rendering Applications in Medical Imaging

    OpenAIRE

    Lindfors, Lisa; Lindmark, Hanna

    2002-01-01

    Volume rendering applications are used in medical imaging in order to facilitate the analysis of three-dimensional image data. This study focuses on how to improve the usability of graphical user interfaces of these systems, by gathering user requirements. This is achieved by evaluations of existing systems, together with interviews and observations at clinics in Sweden that use volume rendering to some extent. The usability of the applications of today is not sufficient, according to the use...

  13. Space station needs, attributes and architectural options study. Volume 3: Mission requirements

    Science.gov (United States)

    1983-04-01

    User missions that are enabled or enhanced by a manned space station are identified. The mission capability requirements imposed on the space station by these users are delineated. The accommodation facilities, equipment, and functional requirements necessary to achieve these capabilities are identified, and the economic, performance, and social benefits which accrue from the space station are defined.

  14. Explicit solutions to correlation matrix completion problems, with an application to risk management and insurance.

    Science.gov (United States)

    Georgescu, Dan I; Higham, Nicholas J; Peters, Gareth W

    2018-03-01

    We derive explicit solutions to the problem of completing a partially specified correlation matrix. Our results apply to several block structures for the unspecified entries that arise in insurance and risk management, where an insurance company with many lines of business is required to satisfy certain capital requirements but may have incomplete knowledge of the underlying correlation matrix. Among the many possible completions, we focus on the one with maximal determinant. This has attractive properties and we argue that it is suitable for use in the insurance application. Our explicit formulae enable easy solution of practical problems and are useful for testing more general algorithms for the maximal determinant correlation matrix completion problem.

  15. Target volume determination in radiotherapy for non-small-cell lung cancer-facts and questions

    International Nuclear Information System (INIS)

    Kepka, L.; Bujko, K.

    2003-01-01

    Although the precise target volume definition in conformal radiotherapy is required by ICRU Report 50 and 62, this task in radiotherapy for non-small-cell lung cancer (NSCLC) is often controversial and strict accordance with ICRU requirements is hard to achieve. The Gross Tumour Volume (GTV) definition depends mainly on the imaging method used. We discuss the use of new imaging modalities, like PET, in GTV definition. The Clinical Target Volume (CTV) definition remains a separate, and still unresolved problem, especially in the part concerning the Elective Nodal Irradiation (ENI). Nowadays, there is no unified attitude among radiation oncologists regarding the necessity and extent of ENI. The common use of combined treatment modalities and the tendency to dose escalation, both increasing the potential toxicity, result in the more frequent use of involved-fields techniques. Problems relating to margins during Planning Target Volume (PTV) of lung cancer irradiation are also discussed. Another issue is the Interclinician variability in target volumes definition, especially when there is data indicating that the GTV, as defined by 3 D-treatment planning in NSCLC radiotherapy, may be highly prognostic for survival. We postulate that special attention should be paid to detailed precision of target volume determination in departmental and trial protocols. Careful analysis of patterns of failures from ongoing protocols will enable us to formulate the guidelines for target volume definition in radiotherapy for lung cancer. (author)

  16. Comparison of uncertainties related to standardization of urine samples with volume and creatinine concentration

    DEFF Research Database (Denmark)

    Garde, Anne Helene; Hansen, Ase Marie; Kristiansen, Jesper

    2004-01-01

    When measuring biomarkers in urine, volume (and time) or concentration of creatinine are both accepted methods of standardization for diuresis. Both types of standardization contribute uncertainty to the final result. The aim of the present paper was to compare the uncertainty introduced when usi...... increase in convenience for the participants, when collecting small volumes rather than complete 24 h samples....... the two types of standardization on 24 h samples from healthy individuals. Estimates of uncertainties were based on results from the literature supplemented with data from our own studies. Only the difference in uncertainty related to the two standardization methods was evaluated. It was found...... that the uncertainty associated with creatinine standardization (19-35%) was higher than the uncertainty related to volume standardization (up to 10%, when not correcting for deviations from 24 h) for 24 h urine samples. However, volume standardization introduced an average bias of 4% due to missed volumes...

  17. Changes in atheroma volume estimated from digitized femoral arteriograms

    International Nuclear Information System (INIS)

    Nilsson, S.; Erikson, U.

    1990-01-01

    To evaluate the effects of treatment in patients with cardiovascular risk factors, valid and reproducible methods for assessing changes in atheroma volume are required. We postulated that these changes could be accurately estimated by repeat measurement of the lumen volume of the artery to be studied. With a computer-based technique, the lumen volume of a 20 cm segment of the femoral artery was measured in arteriograms from 107 patients with hypercholesterolemia. Films were digitized with use of a high-resolution scanner, cross-sectional areas were calculated with a slice thickness of 150 μm and the lumen volume was obtained by their integration. The validity of the method was demonstrated in model experiments. An automatic algorithm to correct for changes due to patient positioning was developed and validated in a model experiment. With repeat measurment 10 min and 11 to 13 months apart the coefficients of variation were 2.9% (N=107) and 6.1% (N=29), respectively. (orig.)

  18. Auto-recognition of surfaces and auto-generation of material removal volume for finishing process

    Science.gov (United States)

    Kataraki, Pramod S.; Salman Abu Mansor, Mohd

    2018-03-01

    Auto-recognition of a surface and auto-generation of material removal volumes for the so recognised surfaces has become a need to achieve successful downstream manufacturing activities like automated process planning and scheduling. Few researchers have contributed to generation of material removal volume for a product but resulted in material removal volume discontinuity between two adjacent material removal volumes generated from two adjacent faces that form convex geometry. The need for limitation free material removal volume generation was attempted and an algorithm that automatically recognises computer aided design (CAD) model’s surface and also auto-generate material removal volume for finishing process of the recognised surfaces was developed. The surfaces of CAD model are successfully recognised by the developed algorithm and required material removal volume is obtained. The material removal volume discontinuity limitation that occurred in fewer studies is eliminated.

  19. Computerized 50 liter volume calibration system

    International Nuclear Information System (INIS)

    Proffitt, T.H.

    1990-01-01

    A system has been designed for the Savannah River Site that will be used to calibrate product shipping containers. For accountability purposes, it is necessary that these containers be calibrated to a very high precision. The Computerized 50 Liter Volume Calibration System (CVCS), which is based on the Ideal Gas Law (IGL), will use reference volumes with precision of no less ±0.03%, and helium to calibrate the containers to have a total error of no greater than ±0.10%. A statistical interpretation of the system has given a theoretical total calculated error of ±0.08%. Tests with the system will be performed once fabrication is complete to experimentally verify the calculated error. Since the total error was calculated using the worst case scenario, the actual error should be significantly less than the calculated value. The computer controlled, totally automated system is traceable to the National Institute of Standards and Technology. The design, calibration procedure, and statistical interpretation of the system will be discussed. 1 ref

  20. Site Transition Process Upon Cleanup Completion. Fact Sheet

    International Nuclear Information System (INIS)

    2009-01-01

    After environmental remediation is completed at a site and there is no continuing mission, responsibility for the site and the associated records are transferred to the U.S. Department of Energy (DOE) Office of Legacy Management for post-closure management. Where residual hazards (e.g., disposal cells, ground water contamination) remain, active long-term surveillance and maintenance will be required to ensure protection of human health and the environment

  1. The collected papers of Albert Einstein. - Vol. 11: Cumulative index, bibliography, list of correspondence, chronology, and errata to volumes 1-10

    NARCIS (Netherlands)

    Kox, A.J.; Sauer, T.; Kormos Buchwald, D.; Hirschmann, R.; Moses, O.; Aronin, B.; Stolper, J.

    2009-01-01

    This index volume provides quick access to the most authoritative compilation of documents and information concerning Einstein's work and correspondence for the first half of his life. It offers readers a Cumulative Index to the first ten volumes of the collected papers, the first complete

  2. Single-dose volume regulation algorithm for a gas-compensated intrathecal infusion pump.

    Science.gov (United States)

    Nam, Kyoung Won; Kim, Kwang Gi; Sung, Mun Hyun; Choi, Seong Wook; Kim, Dae Hyun; Jo, Yung Ho

    2011-01-01

    The internal pressures of medication reservoirs of gas-compensated intrathecal medication infusion pumps decrease when medication is discharged, and these discharge-induced pressure drops can decrease the volume of medication discharged. To prevent these reductions, the volumes discharged must be adjusted to maintain the required dosage levels. In this study, the authors developed an automatic control algorithm for an intrathecal infusion pump developed by the Korean National Cancer Center that regulates single-dose volumes. The proposed algorithm estimates the amount of medication remaining and adjusts control parameters automatically to maintain single-dose volumes at predetermined levels. Experimental results demonstrated that the proposed algorithm can regulate mean single-dose volumes with a variation of 98%. © 2010, Copyright the Authors. Artificial Organs © 2010, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  3. RELAP5/MOD3 code manual: User's guide and input requirements. Volume 2

    International Nuclear Information System (INIS)

    1995-08-01

    The RELAP5 code has been developed for best estimate transient simulation of light water reactor coolant systems during postulated accidents. The code models the coupled behavior of the reactor coolant system and the core for loss-of-coolant accidents, and operational transients, such as anticipated transient without scram, loss of offsite power, loss of feedwater, and loss of flow. A generic modeling approach is used that permits simulating a variety of thermal hydraulic systems. Control system and secondary system components are included to permit modeling of plant controls, turbines, condensers, and secondary feedwater systems. Volume II contains detailed instructions for code application and input data preparation

  4. Patient satisfaction: does surgical volume matter?

    Science.gov (United States)

    Tevis, Sarah E; Kennedy, Gregory D

    2015-06-01

    Patient satisfaction is an increasing area of interest due to implications of pay for performance and public reporting of results. Although scores are adjusted for patient factors, little is known about the relationship between hospital structure, postoperative outcomes, and patient satisfaction with the hospital experience. Hospitals participating in the University HealthSystem Consortium database from 2011-2012 were included. Patients were restricted to those discharged by general surgeons to isolate surgical patients. Hospital data were paired with Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) results from the Hospital Compare website. Postoperative outcomes were dichotomized based on the median for all hospitals and stratified based on surgical volume. The primary outcome of interest was high on overall patient satisfaction, whereas other HCAHPS domains were assessed as secondary outcomes. Chi square and binary logistic regression analyses were performed to evaluate whether postoperative outcomes or surgical volume more significantly influenced high patient satisfaction. The study population consisted of 171 hospitals from the University HealthSystem Consortium database. High surgical volume was a more important predictor of overall patient satisfaction regardless of hospital complication (P patient satisfaction on the HCAHPS survey than postoperative outcomes, whereas volume was less predictive in other HCAHPS domains. Patients may require more specific questioning to identify high quality, safe hospitals. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. EUV mask defect inspection and defect review strategies for EUV pilot line and high volume manufacturing

    Science.gov (United States)

    Chan, Y. David; Rastegar, Abbas; Yun, Henry; Putna, E. Steve; Wurm, Stefan

    2010-04-01

    Reducing mask blank and patterned mask defects is the number one challenge for extreme ultraviolet lithography. If the industry succeeds in reducing mask blank defects at the required rate of 10X every year for the next 2-3 years to meet high volume manufacturing defect requirements, new inspection and review tool capabilities will soon be needed to support this goal. This paper outlines the defect inspection and review tool technical requirements and suggests development plans to achieve pilot line readiness in 2011/12 and high volume manufacturing readiness in 2013. The technical specifications, tooling scenarios, and development plans were produced by a SEMATECH-led technical working group with broad industry participation from material suppliers, tool suppliers, mask houses, integrated device manufacturers, and consortia. The paper summarizes this technical working group's assessment of existing blank and mask inspection/review infrastructure capabilities to support pilot line introduction and outlines infrastructure development requirements and tooling strategies to support high volume manufacturing.

  6. 40 CFR 82.156 - Required practices.

    Science.gov (United States)

    2010-07-01

    ... the additional time needed to conduct and complete repairs in a safe working environment will be... creating a safe working environment will require more than 30 weeks; (B) The operator notifies EPA within... the additional time needed to conduct and complete work in a safe environment will be permitted. (iii...

  7. Nuclear fuel technology - Tank calibration and volume determination for nuclear materials accountancy - Part 1: Procedural overview

    International Nuclear Information System (INIS)

    2007-01-01

    Accurate determinations of volume are a fundamental component of any measurement-based system of control and accountability in a facility that processes or stores nuclear materials in liquid form. Volume determinations are typically made with the aid of a calibration or volume measurement equation that relates the response of the tank's measurement system to some independent measure of tank volume. The ultimate purpose of the calibration exercise is to estimate the tank's volume measurement equation (the inverse of the calibration equation), which relates tank volume to measurement system response. The steps carried out to acquire data for estimating the tank's calibration or volume measurement equation are collectively described as the process of tank calibration. This part of ISO 18213 describes procedures for tank calibration and volume determination for nuclear process tanks equipped with pressure-measurement systems for determining liquid content. Specifically, overall guidance is provided for planning a calibration exercise undertaken to obtain the data required for the measurement equation to estimate a tank's volume. The key steps in the procedure are also presented for subsequently using the estimated volume-measurement equation to determine tank liquid volumes. The procedures presented apply specifically to tanks equipped with bubbler probe systems for measuring liquid content. Moreover, these procedures produce reliable results only for clear (i.e. without suspended solids), homogeneous liquids that are at both thermal and static equilibrium. The paper elaborates on scope, physical principles involved, the calibration model, equipment required, a typical tank calibration procedure, calibration planning and pre-calibration activities, and volume determination. A bibliography is provided

  8. Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

    KAUST Repository

    Sicat, Ronell Barrera; Kruger, Jens; Moller, Torsten; Hadwiger, Markus

    2014-01-01

    This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined

  9. Variation in orbitofrontal cortex volume: relation to sex, emotion regulation and affect.

    Science.gov (United States)

    Welborn, B Locke; Papademetris, Xenophon; Reis, Deidre L; Rajeevan, Nallakkandi; Bloise, Suzanne M; Gray, Jeremy R

    2009-12-01

    Sex differences in brain structure have been examined extensively but are not completely understood, especially in relation to possible functional correlates. Our two aims in this study were to investigate sex differences in brain structure, and to investigate a possible relation between orbitofrontal cortex subregions and affective individual differences. We used tensor-based morphometry to estimate local brain volume from MPRAGE images in 117 healthy right-handed adults (58 female), age 18-40 years. We entered estimates of local brain volume as the dependent variable in a GLM, controlling for age, intelligence and whole-brain volume. Men had larger left planum temporale. Women had larger ventromedial prefrontal cortex (vmPFC), right lateral orbitofrontal (rlOFC), cerebellum, and bilateral basal ganglia and nearby white matter. vmPFC but not rlOFC volume covaried with self-reported emotion regulation strategies (reappraisal, suppression), expressivity of positive emotions (but not of negative), strength of emotional impulses, and cognitive but not somatic anxiety. vmPFC volume statistically mediated sex differences in emotion suppression. The results confirm prior reports of sex differences in orbitofrontal cortex structure, and are the first to show that normal variation in vmPFC volume is systematically related to emotion regulation and affective individual differences.

  10. Design requirements for SRB production control system. Volume 1: Study background and overview

    Science.gov (United States)

    1981-01-01

    The solid rocket boosters assembly environment is described in terms of the contraints it places upon an automated production control system. The business system generated for the SRB assembly and the computer system which meets the business system requirements are described. The selection software process and modifications required to the recommended software are addressed as well as the hardware and configuration requirements necessary to support the system.

  11. STRATEGIES OF COMPLETE ORAL REHABILITATION IN PATIENTS WITH DISFUNCTIONAL SYNDROM OF THE STOMATOGNATE SYSTEM

    Directory of Open Access Journals (Sweden)

    Vasile BURLUI

    2015-12-01

    Full Text Available The complete oral and dental rehabilitation (ROC or (CODR requires an advanced understanding level, based on the capacity to prepare and successfully fix the complete strategy for the complex oral rehabilitation had in view.The method applied was to subject a representative group of patients to the algorithm of diagnosis and clinical solution. The strategies of complete oral rehabilitation applied included surgical-periodontal, implanto-surgical, implanto-prosthetic rehabilitation techniques.

  12. 48 CFR 9903.202-1 - General requirements.

    Science.gov (United States)

    2010-10-01

    ... ACCOUNTING STANDARDS CONTRACT COVERAGE CAS Program Requirements 9903.202-1 General requirements. (a) A... subcontract is of the type or value exempted by 9903.201-1 or (ii) In the most recently completed cost... of Germany. (3) United Kingdom. (f) Educational institutions—disclosure requirements. (1) Educational...

  13. Volume distribution in saw-timber types in the ponderosa pine region.

    Science.gov (United States)

    Stephen N. Wyckoff

    1939-01-01

    The forest survey, a Nation-wide project authorized by Congress in 1928, consists of a complete and detailed investigation of the country's present and future forest resources in five major parts: (1) an inventory of the country's existing forest resources in terms of areas occupied by forest-cover types and of timber volumes, by species, in board feet and...

  14. ON-Line Monitoring of Instrument Channel Performance: Volume 3: Applications to Nuclear Power Plant Technical Specification Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    E Davis, B Rasmussen

    2004-12-31

    This report is a guide for a technical specification change submittal and subsequent implementation of on-line monitoring for safety-related applications. This report is the third in a three-volume set. Volume 1, ''Guidelines for Model Development and Implementation'', presents the various tasks that must be completed to prepare models for and to implement an on-line monitoring system.

  15. Analysis and forecast of electrical distribution system materials. Final report. Volume III. Appendix

    Energy Technology Data Exchange (ETDEWEB)

    Love, C G

    1976-08-23

    These appendixes are referenced in Volume II of this report. They contain the detailed electrical distribution equipment requirements and input material requirements forecasts. Forecasts are given for three electric energy usage scenarios. Also included are data on worldwide reserves and demand for 30 raw materials required for the manufacture of electrical distribution equipment.

  16. The completed Management Information System for the Monterey Navy Flying Club.

    OpenAIRE

    Graham, James M.

    1987-01-01

    Approved for public release; distribution in unlimited. This thesis provides a completed Management Information System for the Monterey Navy Flying Club. The software package was designed to operate upon an IBM PC-XT or PC-AT or 100% compatible microcomputer wjiich has 384K of main memory. Specific hardware requirements are discussed in chapter one. This software package supplies the necessary tools for the club manager to maintain all club records and generate required a...

  17. 6th international symposium on finite volumes for complex applications

    CERN Document Server

    Halama, Jan; Herbin, Raphaèle; Hubert, Florence; Fort, Jaroslav; FVCA 6; Finite Volumes for Complex Applications VI : Problems and perspectives

    2011-01-01

    Finite volume methods are used for various applications in fluid dynamics, magnetohydrodynamics, structural analysis or nuclear physics. A closer look reveals many interesting phenomena and mathematical or numerical difficulties, such as true error analysis and adaptivity, modelling of multi-phase phenomena or fitting problems, stiff terms in convection/diffusion equations and sources. To overcome existing problems and to find solution methods for future applications requires many efforts and always new developments. The goal of The International Symposium on Finite Volumes for Complex Applica

  18. Orthodontic treatment of a complete transposed impacted maxillary canine

    Directory of Open Access Journals (Sweden)

    Pi-Huei Liu

    2015-03-01

    Full Text Available Tooth transposition is a positional interchange of two adjacent teeth. Transposition most often occurs at maxillary canine. Moving transposed teeth to their normal positions is challenging because this requires bodily movement and translation of one tooth to pass another. This procedure may cause damage to the teeth or supporting structures. We report a case of complete transposition of maxillary canine and lateral incisor. Transposed teeth were successfully moved orthodontically to their normal positions. Multiple mechanics were meticulously applied to achieve complete correction of the tooth positions and to minimize root resorption and/or periodontal defects of canine and lateral incisors. Factors concerning treatment planning for transposed teeth are discussed.

  19. Clipping of tumour resection margins allows accurate target volume delineation in head and neck cancer adjuvant radiation therapy

    International Nuclear Information System (INIS)

    Bittermann, Gido; Wiedenmann, Nicole; Bunea, Andrei; Schwarz, Steffen J.; Grosu, Anca-L.; Schmelzeisen, Rainer; Metzger, Marc C.

    2015-01-01

    Background: Accurate tumour bed localisation is a key requirement for adjuvant radiotherapy. A new procedure is described for head and neck cancer treatment that improves tumour bed localisation using titanium clips. Materials and methods: Following complete local excision of the primary tumour, the tumour bed was marked with titanium clips. Preoperative gross target volume (GTV) and postoperative tumour bed were examined and the distances between the centres of gravity were evaluated. Results: 49 patients with squamous cell carcinoma of the oral cavity were prospectively enrolled in this study. All patients underwent tumour resection, neck lymph node dissection and defect reconstruction in one stage. During surgery, 7–49 clips were placed in the resection cavity. Surgical clip insertion was successful in 88% (n = 43). Clip identification and tumour bed delineation was successful in all 43 patients. The overall distance between the centres of gravity of the preoperative tumour extension to the tumour bed was 0.9 cm. A significant relationship between the preoperative tumour extension and the postoperative tumour bed volume could be demonstrated. Conclusion: We demonstrate a precise delineation of the former tumour cavity. Improvements in tumour bed delineation allow an increase of accuracy for adjuvant treatment

  20. Target volumes in gastric cancer radiation therapy

    International Nuclear Information System (INIS)

    Caudry, M.; Maire, J.P.; Ratoanina, J.L.; Escarmant, P.

    2001-01-01

    The spread of gastric adenocarcinoma may follow three main patterns: hemato-genic, lymphatic and intraperitoneal. A GTV should be considered in preoperative or exclusive radiation therapy. After non-radical surgery, a 'residual GTV' will be defined with the help of the surgeon. The CTV encompasses three intricated volumes. a) A 'tumor bed' volume. After radical surgery, local recurrences appear as frequent as distant metastases. The risk depends upon the depth of parietal invasion and the nodal status. Parietal infiltration may extend beyond macroscopic limits of the tumor, especially in dinitis plastica. Therefore this volume will include: the tumor and the remaining stomach or their 'bed of resection', a part of the transverse colon, the duodenum, the pancreas and the troncus of the portal vein. In postoperative RT, this CTV also includes the jejuno-gastric or jejuno-esophageal anastomosis. b) A peritoneal volume. For practical purposes, two degrees of spread must be considered: (1) contiguous microscopic extension from deeply invasive T3 and T4 tumors, that remain amenable to local sterilization with doses of 45-50 Gy, delivered in a CTV including the peritoneal cavity at the level of the gastric bed, and under the parietal incision; (2) true 'peritoneal carcinomatosis', with widespread seeds, where chemotherapy (systemic or intraperitoneal) is more appropriate. c) A lymphatic volume including the lymph node groups 1 to 16 of the Japanese classification. This volume must encompass the hepatic pedicle and the splenic hilum. In proximal tumors, it is possible to restrict the lover part of the CTV to the lymphatic volume, and therefore to avoid irradiation of large intestinal and renal volumes. In distal and proximal tumors, involvement of resection margins is of poor prognosis -a radiation boost must be delivered at this level. The CTV in tumors of the cardia should encompass the lover part of the thoracic esophagus and the corresponding posterior mediastinum. In

  1. Information architecture. Volume 2, Part 1: Baseline analysis summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    The Department of Energy (DOE) Information Architecture, Volume 2, Baseline Analysis, is a collaborative and logical next-step effort in the processes required to produce a Departmentwide information architecture. The baseline analysis serves a diverse audience of program management and technical personnel and provides an organized way to examine the Department`s existing or de facto information architecture. A companion document to Volume 1, The Foundations, it furnishes the rationale for establishing a Departmentwide information architecture. This volume, consisting of the Baseline Analysis Summary (part 1), Baseline Analysis (part 2), and Reference Data (part 3), is of interest to readers who wish to understand how the Department`s current information architecture technologies are employed. The analysis identifies how and where current technologies support business areas, programs, sites, and corporate systems.

  2. The spill prevention, control, and countermeasures (SPCC) plan for the Y-12 Plant. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-01

    This spill prevention, control and countermeasures (SPCC) Plan is divided into two volumes. Volume I addresses Y-12`s compliance with regulations pertinent to the content of SPCC Plans. Volume II is the SPCC Hazardous Material Storage Data Base, a detailed tabulation of facility-specific information and data on potential spill sources at the Y-12 Plant. Volume I follows the basic format and subject sequence specified in 40 CFR 112.7. This sequence is prefaced by three additional chapters, including this introduction and brief discussions of the Y-12 Plant`s background/environmental setting and potential spill source categories. Two additional chapters on containers and container storage areas and PCB and PCB storage for disposal facilities are inserted into the required sequence. The following required subjects are covered in this volume: Spill history, site drainage; secondary containment/diversion structures and equipment; contingency plans; notification and spill response procedures; facility drainage; bulk storage tanks; facility transfer operations, pumping, and in-plant processes; transfer stations (facility tank cars/tank tracks); inspections and records; security, and personnel, training, and spill prevention procedures.

  3. Technology for Space Station Evolution. Volume 3: EVA/Manned Systems/Fluid Management System

    Science.gov (United States)

    1990-01-01

    NASA's Office of Aeronautics and Space Technology (OAST) conducted a workshop on technology for space station evolution 16-19 Jan. 1990 in Dallas, Texas. The purpose of this workshop was to collect and clarify Space Station Freedom technology requirements for evolution and to describe technologies that can potentially fill those requirements. These proceedings are organized into an Executive Summary and Overview and five volumes containing the Technology Discipline Presentations. Volume 3 consists of the technology discipline sections for Extravehicular Activity/Manned Systems and the Fluid Management System. For each technology discipline, there is a Level 3 subsystem description, along with the papers.

  4. FDG-PET imaging for the assessment of physiologic volume response during radiotherapy in cervix cancer

    International Nuclear Information System (INIS)

    Lin, Lilie L.; Yang Zhiyun; Mutic, Sasa; Miller, Tom R.; Grigsby, Perry W.

    2006-01-01

    Purpose: To evaluate the physiologic tumor volume response during treatment in cervical cancer using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET). Patients and Methods: This was a prospective study of 32 patients. Physiologic tumor volume in cubic centimeters was determined from the FDG-PET images using the 40% threshold method. Results: The mean pretreatment tumor volume was 102 cm 3 . The mean volume by clinical Stages I, II, and III were 54, 79, and 176 cm 3 , respectively. After 19.8 Gy external irradiation to the pelvis, the reduction in tumor volume was 29% (72 cm 3 ). An additional 13 Gy from high-dose-rate (HDR) brachytherapy reduced the mean volume to 15.4 cm 3 , and this was subsequently reduced to 8.6 cm 3 with 13 Gy additional HDR brachytherapy (26 Gy, HDR). Four patients had physiologic FDG uptake in the cervix at 3 months after the completion of therapy. The mean time to the 50% reduction in physiologic tumor volume was 19.9 days and after combined external irradiation and HDR to 24.9 Gy. Conclusion: These results indicate that physiologic tumor volume determination by FDG-PET is feasible and that a 50% physiologic tumor volume reduction occurs within 20 days of starting therapy

  5. Gastric volvulus with partial and complete gastric necrosis

    Science.gov (United States)

    Shukla, Ram Mohan; Mandal, Kartik Chandra; Maitra, Sujay; Ray, Amit; Sarkar, Ruchirendu; Mukhopadhyay, Biswanath; Bhattacharya, Malay

    2014-01-01

    Here, we report two interesting cases of gastric necrosis in acute gastric volvulus due to eventration of the diaphragm. Both the cases presented with a significant challenge and were managed successfully. The management of the cases is presented and relevant literature is discussed. To the best of our knowledge, this is the first case report of gastric volvulus with gastric necrosis requiring complete and partial gastrectomy in the available English literature. PMID:24604987

  6. Gastric volvulus with partial and complete gastric necrosis

    Directory of Open Access Journals (Sweden)

    Ram Mohan Shukla

    2014-01-01

    Full Text Available Here, we report two interesting cases of gastric necrosis in acute gastric volvulus due to eventration of the diaphragm. Both the cases presented with a significant challenge and were managed successfully. The management of the cases is presented and relevant literature is discussed. To the best of our knowledge, this is the first case report of gastric volvulus with gastric necrosis requiring complete and partial gastrectomy in the available English literature.

  7. Frequency Domain Computer Programs for Prediction and Analysis of Rail Vehicle Dynamics : Volume 1. Technical Report

    Science.gov (United States)

    1975-12-01

    Frequency domain computer programs developed or acquired by TSC for the analysis of rail vehicle dynamics are described in two volumes. Volume I defines the general analytical capabilities required for computer programs applicable to single rail vehi...

  8. Brain Volume Estimation Enhancement by Morphological Image Processing Tools

    Directory of Open Access Journals (Sweden)

    Zeinali R.

    2017-12-01

    Full Text Available Background: Volume estimation of brain is important for many neurological applications. It is necessary in measuring brain growth and changes in brain in normal/ abnormal patients. Thus, accurate brain volume measurement is very important. Magnetic resonance imaging (MRI is the method of choice for volume quantification due to excellent levels of image resolution and between-tissue contrast. Stereology method is a good method for estimating volume but it requires to segment enough MRI slices and have a good resolution. In this study, it is desired to enhance stereology method for volume estimation of brain using less MRI slices with less resolution. Methods: In this study, a program for calculating volume using stereology method has been introduced. After morphologic method, dilation was applied and the stereology method enhanced. For the evaluation of this method, we used T1-wighted MR images from digital phantom in BrainWeb which had ground truth. Results: The volume of 20 normal brain extracted from BrainWeb, was calculated. The volumes of white matter, gray matter and cerebrospinal fluid with given dimension were estimated correctly. Volume calculation from Stereology method in different cases was made. In three cases, Root Mean Square Error (RMSE was measured. Case I with T=5, d=5, Case II with T=10, D=10 and Case III with T=20, d=20 (T=slice thickness, d=resolution as stereology parameters. By comparing these results of two methods, it is obvious that RMSE values for our proposed method are smaller than Stereology method. Conclusion: Using morphological operation, dilation allows to enhance the estimation volume method, Stereology. In the case with less MRI slices and less test points, this method works much better compared to Stereology method.

  9. INEL environmental characterization report. Volume II. Appendices A-D

    International Nuclear Information System (INIS)

    1984-09-01

    This volume contains appendices: (1) a socioeconomic data base for southeastern Idaho; (2) an ecological characterization of the INEL; (3) site-specific climatology summary, NPR primary and alternate sites; (4) NPR site borehole completion; (5) an investigation of the principal lineament at the INEL; (6) an investigation of Clay Butte, Idaho; (7) Arco and Howe fault study; (8) seismology of the INEL; (9) geologic map of the INEL; and (1) geologic ages of the INEL

  10. Measuring stone volume - three-dimensional software reconstruction or an ellipsoid algebra formula?

    Science.gov (United States)

    Finch, William; Johnston, Richard; Shaida, Nadeem; Winterbottom, Andrew; Wiseman, Oliver

    2014-04-01

    To determine the optimal method for assessing stone volume, and thus stone burden, by comparing the accuracy of scalene, oblate, and prolate ellipsoid volume equations with three-dimensional (3D)-reconstructed stone volume. Kidney stone volume may be helpful in predicting treatment outcome for renal stones. While the precise measurement of stone volume by 3D reconstruction can be accomplished using modern computer tomography (CT) scanning software, this technique is not available in all hospitals or with routine acute colic scanning protocols. Therefore, maximum diameters as measured by either X-ray or CT are used in the calculation of stone volume based on a scalene ellipsoid formula, as recommended by the European Association of Urology. In all, 100 stones with both X-ray and CT (1-2-mm slices) were reviewed. Complete and partial staghorn stones were excluded. Stone volume was calculated using software designed to measure tissue density of a certain range within a specified region of interest. Correlation coefficients among all measured outcomes were compared. Stone volumes were analysed to determine the average 'shape' of the stones. The maximum stone diameter on X-ray was 3-25 mm and on CT was 3-36 mm, with a reasonable correlation (r = 0.77). Smaller stones (15 mm towards scalene ellipsoids. There was no difference in stone shape by location within the kidney. As the average shape of renal stones changes with diameter, no single equation for estimating stone volume can be recommended. As the maximum diameter increases, calculated stone volume becomes less accurate, suggesting that larger stones have more asymmetric shapes. We recommend that research looking at stone clearance rates should use 3D-reconstructed stone volumes when available, followed by prolate, oblate, or scalene ellipsoid formulas depending on the maximum stone diameter. © 2013 The Authors. BJU International © 2013 BJU International.

  11. Reduction of waste solution volume generated on electrokinetic remediation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Gye-Nam; Koo, Dae-Seo; Kim, Seung-Soo; Jeong, Jung-Whan; Han, Gyu-Seong; Moon, Jei-Kwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    In this study, for the reduction of volume of metal oxides generated in cathode chamber, the optimum pH of waste electrolyte in cathode chamber were drawn out through several experiments with the manufactured electrokinetic decontamination equipment. Also, the required time to reach to below the clearance concentration level for self- disposal was estimated through experiments using the manufactured electrokinetic decontamination equipment. A diagram of soil decontamination process for the removal of uranium from contaminated soil was drawn out. The optimum pH of waste electrolyte in cathode chamber for the reduction of volume of metal oxides was below 2.35. Also, when the initial uranium concentration of the soils were 7-20 Bq/g, the required times to reach to below the clearance concentration level for self- disposal were 25-40 days. A diagram of soil decontamination process for the removal of uranium from contaminated soil was drawn out.

  12. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 5. Baseline rock properties-granite

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Y/OWI/TM-36/5, Baseline Rock Properties--Granite, is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations, Y/OWI/TM-36'' which supplements a ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations, Y/OWI/TM-44.'' The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This report, on the rock properties of typical granites, includes an evaluation of the various test results reported in the literature. Firstly, a literature survey was made in order to obtain a feel for the range of rock properties encountered. Then, granites representative of different geologic ages and from different parts of the United States were selected and studied in further detail. Some of the special characteristics of granite, such as anisotropy, creep and weathering were also investigated. Lastly, intact properties for a typical granite were selected and rock mass properties were derived using appropriate correction factors

  13. The Voronoi volume and molecular representation of molar volume: equilibrium simple fluids.

    Science.gov (United States)

    Hunjan, Jagtar Singh; Eu, Byung Chan

    2010-04-07

    The Voronoi volume of simple fluids was previously made use of in connection with volume transport phenomena in nonequilibrium simple fluids. To investigate volume transport phenomena, it is important to develop a method to compute the Voronoi volume of fluids in nonequilibrium. In this work, as a first step to this goal, we investigate the equilibrium limit of the nonequilibrium Voronoi volume together with its attendant related molar (molal) and specific volumes. It is proved that the equilibrium Voronoi volume is equivalent to the molar (molal) volume. The latter, in turn, is proved equivalent to the specific volume. This chain of equivalences provides an alternative procedure of computing the equilibrium Voronoi volume from the molar volume/specific volume. We also show approximate methods of computing the Voronoi and molar volumes from the information on the pair correlation function. These methods may be employed for their quick estimation, but also provide some aspects of the fluid structure and its relation to the Voronoi volume. The Voronoi volume obtained from computer simulations is fitted to a function of temperature and pressure in the region above the triple point but below the critical point. Since the fitting function is given in terms of reduced variables for the Lennard-Jones (LJ) model and the kindred volumes (i.e., specific and molar volumes) are in essence equivalent to the equation of state, the formula obtained is a reduced equation state for simple fluids obeying the LJ model potential in the range of temperature and pressure examined and hence can be used for other simple fluids.

  14. Market designs for a completely renewable power sector

    Energy Technology Data Exchange (ETDEWEB)

    Winkler, Jenny [Fraunhofer-Institut fuer System- und Innovationsforschung (ISI), Karlsruhe (Germany); Altmann, Matthias [Ludwig-Boelkow-Systemtechnik GmbH, Ottobrunn (Germany)

    2012-06-15

    The article discusses whether the current German electricity market design is suitable for an electricity system completely based on renewable sources, and analyzes alternatives. Such a system becomes ever more likely due to the phase-out of nuclear power and the carbon reduction targets. Various existing scenarios for a completely renewable electricity system are analyzed and compared with respect to the contribution of different renewable technologies. Challenges for the market design arising from the differences between the current and a completely renewable system are identified - notably problems with cost recovery and investment incentives, an increased need for balancing and/or intraday adjustments, an increased diversity of actors, grid congestion and the continuing occurrence of market power. The current market design's ability to solve these issues is assessed with the result that all but the critical problem of investment incentives and cost recovery can be solved by adapting certain rules. A comparison with other suggested market designs reveals that some designs could ensure cost recovery and investment incentives. However, these market designs have other drawbacks. Therefore, the identification of the optimal market design for a completely renewable electricity system requires further research regarding the qualitative and quantitative effects of different changes to the current market design. The article concludes by developing concrete policy recommendations. (orig.)

  15. Colloquial French the complete course for beginners

    CERN Document Server

    Demouy, Valérie

    2015-01-01

    Colloquial French: The Complete Course for Beginners has been carefully developed by an experienced teacher to provide a step-by-step course to French as it is written and spoken today. Combining a clear, practical and accessible style with a methodical and thorough treatment of the language, it equips learners with the essential skills needed to communicate confidently and effectively in French in a broad range of situations. No prior knowledge of the language is required. Colloquial French is exceptional; each unit presents a wealth of grammatical points that are reinforced with a wide range

  16. Second interim assessment of the Canadian concept for nuclear fuel waste disposal. Volume 3

    International Nuclear Information System (INIS)

    Johansen, K.; Donnelly, K.J.; Gee, J.H.; Green, B.J.; Nathwani, J.S.; Quinn, A.M.; Rogers, B.G.; Stevenson, M.A.; Dunford, W.E.; Tamm, J.A.

    1985-12-01

    The nuclear fuel waste disposal concept chosen for development and assessment in Canada involves the isolation of corrosion-resistant containers of waste in a vault located deep in plutonic rock. As the concept and the assessment tools are developed, periodic assessments are performed to permit evaluation of the methodology and provide feedback to those developing the concept. The ultimate goal of these assessments is to predict what impact the disposal system would have on man and the environment if the concept were implemented. The second such assessment was completed in 1984 and is documented in the Second Interim Assessment of the Canadian Concept for Nuclear Fuel Waste Disposal - Volumes 1-4. This, the third volume of the report, summarizes the pre-closure environmental and safety assessments completed by Ontario Hydro for Atomic Energy of Canada Limited. The preliminary results and their sigificance are discussed. 85 refs

  17. Breastfeeding and Childhood IQ: The Mediating Role of Gray Matter Volume.

    Science.gov (United States)

    Luby, Joan L; Belden, Andy C; Whalen, Diana; Harms, Michael P; Barch, Deanna M

    2016-05-01

    A substantial body of literature has established the positive effect of breastfeeding on child developmental outcomes. There is increasing consensus that breastfed children have higher IQs after accounting for key variables, including maternal education, IQ, and socioeconomic status. Cross-sectional investigations of the effects of breastfeeding on structural brain development suggest that breastfed infants have larger whole brain, cortical, and white matter volumes. To date, few studies have related these measures of brain structure to IQ in breastfed versus nonbreastfed children in a longitudinal sample. Data were derived from the Preschool Depression Study (PDS), a prospective longitudinal study in which children and caregivers were assessed annually for 8 waves over 11 years. A subset completed neuroimaging between the ages of 9.5 and 14.11 years. A total of 148 individuals had breastfeeding data at baseline and complete data on all variables of interest, including IQ and structural neuroimaging. General linear models and process mediation models were used. Breastfed children had significantly higher IQ scores and larger whole brain, total gray matter, total cortical gray matter, and subcortical gray matter volumes compared with the nonbreastfed group in models that covaried for key variables. Subcortical gray matter volume significantly mediated the association between breastfeeding and children's IQ scores. The study findings suggest that the effects of breastfeeding on child IQ are mediated through subcortical gray volume. This effect and putative mechanism is of public health significance and further supports the importance of breastfeeding in mental health promotion. Copyright © 2016 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  18. Prehospital tidal volume influences hospital tidal volume: A cohort study.

    Science.gov (United States)

    Stoltze, Andrew J; Wong, Terrence S; Harland, Karisa K; Ahmed, Azeemuddin; Fuller, Brian M; Mohr, Nicholas M

    2015-06-01

    The purposes of the study are to describe current practice of ventilation in a modern air medical system and to measure the association of ventilation strategy with subsequent ventilator care and acute respiratory distress syndrome (ARDS). Retrospective observational cohort study of intubated adult patients (n = 235) transported by a university-affiliated air medical transport service to a 711-bed tertiary academic center between July 2011 and May 2013. Low tidal volume ventilation was defined as tidal volumes less than or equal to 8 mL/kg predicted body weight. Multivariable regression was used to measure the association between prehospital tidal volume, hospital ventilation strategy, and ARDS. Most patients (57%) were ventilated solely with bag valve ventilation during transport. Mean tidal volume of mechanically ventilated patients was 8.6 mL/kg predicted body weight (SD, 0.2 mL/kg). Low tidal volume ventilation was used in 13% of patients. Patients receiving low tidal volume ventilation during air medical transport were more likely to receive low tidal volume ventilation in the emergency department (P tidal volume (P = .840). Low tidal volume ventilation was rare during air medical transport. Air transport ventilation strategy influenced subsequent ventilation but was not associated with ARDS. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Computer-aided measurement of liver volumes in CT by means of geodesic active contour segmentation coupled with level-set algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Kenji; Kohlbrenner, Ryan; Epstein, Mark L.; Obajuluwa, Ademola M.; Xu Jianwu; Hori, Masatoshi [Department of Radiology, University of Chicago, 5841 South Maryland Avenue, Chicago, Illinois 60637 (United States)

    2010-05-15

    Purpose: Computerized liver extraction from hepatic CT images is challenging because the liver often abuts other organs of a similar density. The purpose of this study was to develop a computer-aided measurement of liver volumes in hepatic CT. Methods: The authors developed a computerized liver extraction scheme based on geodesic active contour segmentation coupled with level-set contour evolution. First, an anisotropic diffusion filter was applied to portal-venous-phase CT images for noise reduction while preserving the liver structure, followed by a scale-specific gradient magnitude filter to enhance the liver boundaries. Then, a nonlinear grayscale converter enhanced the contrast of the liver parenchyma. By using the liver-parenchyma-enhanced image as a speed function, a fast-marching level-set algorithm generated an initial contour that roughly estimated the liver shape. A geodesic active contour segmentation algorithm coupled with level-set contour evolution refined the initial contour to define the liver boundaries more precisely. The liver volume was then calculated using these refined boundaries. Hepatic CT scans of 15 prospective liver donors were obtained under a liver transplant protocol with a multidetector CT system. The liver volumes extracted by the computerized scheme were compared to those traced manually by a radiologist, used as ''gold standard.''Results: The mean liver volume obtained with our scheme was 1504 cc, whereas the mean gold standard manual volume was 1457 cc, resulting in a mean absolute difference of 105 cc (7.2%). The computer-estimated liver volumetrics agreed excellently with the gold-standard manual volumetrics (intraclass correlation coefficient was 0.95) with no statistically significant difference (F=0.77; p(F{<=}f)=0.32). The average accuracy, sensitivity, specificity, and percent volume error were 98.4%, 91.1%, 99.1%, and 7.2%, respectively. Computerized CT liver volumetry would require substantially less

  20. Computer-aided measurement of liver volumes in CT by means of geodesic active contour segmentation coupled with level-set algorithms

    International Nuclear Information System (INIS)

    Suzuki, Kenji; Kohlbrenner, Ryan; Epstein, Mark L.; Obajuluwa, Ademola M.; Xu Jianwu; Hori, Masatoshi

    2010-01-01

    Purpose: Computerized liver extraction from hepatic CT images is challenging because the liver often abuts other organs of a similar density. The purpose of this study was to develop a computer-aided measurement of liver volumes in hepatic CT. Methods: The authors developed a computerized liver extraction scheme based on geodesic active contour segmentation coupled with level-set contour evolution. First, an anisotropic diffusion filter was applied to portal-venous-phase CT images for noise reduction while preserving the liver structure, followed by a scale-specific gradient magnitude filter to enhance the liver boundaries. Then, a nonlinear grayscale converter enhanced the contrast of the liver parenchyma. By using the liver-parenchyma-enhanced image as a speed function, a fast-marching level-set algorithm generated an initial contour that roughly estimated the liver shape. A geodesic active contour segmentation algorithm coupled with level-set contour evolution refined the initial contour to define the liver boundaries more precisely. The liver volume was then calculated using these refined boundaries. Hepatic CT scans of 15 prospective liver donors were obtained under a liver transplant protocol with a multidetector CT system. The liver volumes extracted by the computerized scheme were compared to those traced manually by a radiologist, used as ''gold standard.''Results: The mean liver volume obtained with our scheme was 1504 cc, whereas the mean gold standard manual volume was 1457 cc, resulting in a mean absolute difference of 105 cc (7.2%). The computer-estimated liver volumetrics agreed excellently with the gold-standard manual volumetrics (intraclass correlation coefficient was 0.95) with no statistically significant difference (F=0.77; p(F≤f)=0.32). The average accuracy, sensitivity, specificity, and percent volume error were 98.4%, 91.1%, 99.1%, and 7.2%, respectively. Computerized CT liver volumetry would require substantially less completion time

  1. Change in brain and lesion volumes after CEE therapies: the WHIMS-MRI studies.

    Science.gov (United States)

    Coker, Laura H; Espeland, Mark A; Hogan, Patricia E; Resnick, Susan M; Bryan, R Nick; Robinson, Jennifer G; Goveas, Joseph S; Davatzikos, Christos; Kuller, Lewis H; Williamson, Jeff D; Bushnell, Cheryl D; Shumaker, Sally A

    2014-02-04

    To determine whether smaller brain volumes in older women who had completed Women's Health Initiative (WHI)-assigned conjugated equine estrogen-based hormone therapy (HT), reported by WHI Memory Study (WHIMS)-MRI, correspond to a continuing increased rate of atrophy an average of 6.1 to 7.7 years later in WHIMS-MRI2. A total of 1,230 WHI participants were contacted: 797 (64.8%) consented, and 729 (59%) were rescanned an average of 4.7 years after the initial MRI scan. Mean annual rates of change in total brain volume, the primary outcome, and rates of change in ischemic lesion volumes, the secondary outcome, were compared between treatment groups using mixed-effect models with adjustment for trial, clinical site, age, intracranial volumes, and time between MRI measures. Total brain volume decreased an average of 3.22 cm(3)/y in the active arm and 3.07 cm(3)/y in the placebo arm (p = 0.53). Total ischemic lesion volumes increased in both arms at a rate of 0.12 cm(3)/y (p = 0.88). Conjugated equine estrogen-based postmenopausal HT, previously assigned at WHI baseline, did not affect rates of decline in brain volumes or increases in brain lesion volumes during the 4.7 years between the initial and follow-up WHIMS-MRI studies. Smaller frontal lobe volumes were observed as persistent group differences among women assigned to active HT compared with placebo. Women with a history of cardiovascular disease treated with active HT, compared with placebo, had higher rates of accumulation in white matter lesion volume and total brain lesion volume. Further study may elucidate mechanisms that explain these findings.

  2. [Evaluation of tidal volume delivered by ventilators during volume-controlled ventilation].

    Science.gov (United States)

    Zhou, Juan; Yan, Yong; Cao, Desen

    2014-12-01

    To study the ways which ensure the delivery of enough tidal volume to patients under various conditions close to the demand of the physician. The volume control ventilation model was chosen, and the simulation lung type was active servo lung ASL 5000 or Michigan lung 1601. The air resistance, air compliance and lung type in simulation lungs were set. The tidal volume was obtained from flow analyzer PF 300. At the same tidal volume, the displaying values of tidal volume of E5, Servo i, Evital 4, and Evital XL ventilators with different lung types of patient, compliance of gas piping, leakage, gas types, etc. were evaluated. With the same setting tidal volume of a same ventilator, the tidal volume delivered to patients was different with different lung types of patient, compliance of gas piping, leakage, gas types, etc. Reducing compliance and increasing resistance of the patient lungs caused high peak airway pressure, the tidal volume was lost in gas piping, and the tidal volume be delivered to the patient lungs was decreased. If the ventilator did not compensate to leakage, the tidal volume delivered to the patient lungs was decreased. When the setting gas type of ventilator did not coincide with that applying to the patient, the tidal volume be delivered to the patient lungs might be different with the setting tidal volume of ventilator. To ensure the delivery of enough tidal volume to patients close to the demand of the physician, containable factors such as the compliance of gas piping, leakage, and gas types should be controlled.

  3. Correlation between tumor regression grade and rectal volume in neoadjuvant concurrent chemoradiotherapy for rectal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hong Seok; Choi, Doo Ho; Park, Hee Chul; Park, Won; Yu, Jeong Il; Chung, Kwang Zoo [Dept. of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2016-09-15

    To determine whether large rectal volume on planning computed tomography (CT) results in lower tumor regression grade (TRG) after neoadjuvant concurrent chemoradiotherapy (CCRT) in rectal cancer patients. We reviewed medical records of 113 patients treated with surgery following neoadjuvant CCRT for rectal cancer between January and December 2012. Rectal volume was contoured on axial images in which gross tumor volume was included. Average axial rectal area (ARA) was defined as rectal volume divided by longitudinal tumor length. The impact of rectal volume and ARA on TRG was assessed. Average rectal volume and ARA were 11.3 mL and 2.9 cm². After completion of neoadjuvant CCRT in 113 patients, pathologic results revealed total regression (TRG 4) in 28 patients (25%), good regression (TRG 3) in 25 patients (22%), moderate regression (TRG 2) in 34 patients (30%), minor regression (TRG 1) in 24 patients (21%), and no regression (TRG0) in 2 patients (2%). No difference of rectal volume and ARA was found between each TRG groups. Linear correlation existed between rectal volume and TRG (p = 0.036) but not between ARA and TRG (p = 0.058). Rectal volume on planning CT has no significance on TRG in patients receiving neoadjuvant CCRT for rectal cancer. These results indicate that maintaining minimal rectal volume before each treatment may not be necessary.

  4. Correlation between tumor regression grade and rectal volume in neoadjuvant concurrent chemoradiotherapy for rectal cancer

    International Nuclear Information System (INIS)

    Lee, Hong Seok; Choi, Doo Ho; Park, Hee Chul; Park, Won; Yu, Jeong Il; Chung, Kwang Zoo

    2016-01-01

    To determine whether large rectal volume on planning computed tomography (CT) results in lower tumor regression grade (TRG) after neoadjuvant concurrent chemoradiotherapy (CCRT) in rectal cancer patients. We reviewed medical records of 113 patients treated with surgery following neoadjuvant CCRT for rectal cancer between January and December 2012. Rectal volume was contoured on axial images in which gross tumor volume was included. Average axial rectal area (ARA) was defined as rectal volume divided by longitudinal tumor length. The impact of rectal volume and ARA on TRG was assessed. Average rectal volume and ARA were 11.3 mL and 2.9 cm². After completion of neoadjuvant CCRT in 113 patients, pathologic results revealed total regression (TRG 4) in 28 patients (25%), good regression (TRG 3) in 25 patients (22%), moderate regression (TRG 2) in 34 patients (30%), minor regression (TRG 1) in 24 patients (21%), and no regression (TRG0) in 2 patients (2%). No difference of rectal volume and ARA was found between each TRG groups. Linear correlation existed between rectal volume and TRG (p = 0.036) but not between ARA and TRG (p = 0.058). Rectal volume on planning CT has no significance on TRG in patients receiving neoadjuvant CCRT for rectal cancer. These results indicate that maintaining minimal rectal volume before each treatment may not be necessary

  5. Barriers to Successful Treatment Completion in Child Sexual Abuse Survivors

    Science.gov (United States)

    McPherson, Paul; Scribano, Philip; Stevens, Jack

    2012-01-01

    Child sexual abuse (CSA) often requires psychological treatment to address the symptoms of victim trauma. Barriers to entry and completion of counseling services can compromise long-term well-being. An integrated medical and mental health evaluation and treatment model of a child advocacy center (CAC) has the potential to reduce barriers to mental…

  6. 76 FR 3485 - Required Scale Tests

    Science.gov (United States)

    2011-01-20

    ...-AB10 Required Scale Tests AGENCY: Grain Inspection, Packers and Stockyards Administration, USDA. ACTION... their scales tested at least twice each calendar year at intervals of approximately 6 months. This final rule requires that regulated entities complete the first of the two scale tests between January 1 and...

  7. GLACIER VOLUME CHANGE ESTIMATION USING TIME SERIES OF IMPROVED ASTER DEMS

    Directory of Open Access Journals (Sweden)

    L. Girod

    2016-06-01

    Full Text Available Volume change data is critical to the understanding of glacier response to climate change. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER system embarked on the Terra (EOS AM-1 satellite has been a unique source of systematic stereoscopic images covering the whole globe at 15m resolution and at a consistent quality for over 15 years. While satellite stereo sensors with significantly improved radiometric and spatial resolution are available to date, the potential of ASTER data lies in its long consistent time series that is unrivaled, though not fully exploited for change analysis due to lack of data accuracy and precision. Here, we developed an improved method for ASTER DEM generation and implemented it in the open source photogrammetric library and software suite MicMac. The method relies on the computation of a rational polynomial coefficients (RPC model and the detection and correction of cross-track sensor jitter in order to compute DEMs. ASTER data are strongly affected by attitude jitter, mainly of approximately 4 km and 30 km wavelength, and improving the generation of ASTER DEMs requires removal of this effect. Our sensor modeling does not require ground control points and allows thus potentially for the automatic processing of large data volumes. As a proof of concept, we chose a set of glaciers with reference DEMs available to assess the quality of our measurements. We use time series of ASTER scenes from which we extracted DEMs with a ground sampling distance of 15m. Our method directly measures and accounts for the cross-track component of jitter so that the resulting DEMs are not contaminated by this process. Since the along-track component of jitter has the same direction as the stereo parallaxes, the two cannot be separated and the elevations extracted are thus contaminated by along-track jitter. Initial tests reveal no clear relation between the cross-track and along-track components so that the latter

  8. Design, simulation, and optimization of an RGB polarization independent transmission volume hologram

    Science.gov (United States)

    Mahamat, Adoum Hassan

    Volume phase holographic (VPH) gratings have been designed for use in many areas of science and technology such as optical communication, medical imaging, spectroscopy and astronomy. The goal of this dissertation is to design a volume phase holographic grating that provides diffraction efficiencies of at least 70% for the entire visible wavelengths and higher than 90% for red, green, and blue light when the incident light is unpolarized. First, the complete design, simulation and optimization of the volume hologram are presented. The optimization is done using a Monte Carlo analysis to solve for the index modulation needed to provide higher diffraction efficiencies. The solutions are determined by solving the diffraction efficiency equations determined by Kogelnik's two wave coupled-wave theory. The hologram is further optimized using the rigorous coupled-wave analysis to correct for effects of absorption omitted by Kogelnik's method. Second, the fabrication or recording process of the volume hologram is described in detail. The active region of the volume hologram is created by interference of two coherent beams within the thin film. Third, the experimental set up and measurement of some properties including the diffraction efficiencies of the volume hologram, and the thickness of the active region are conducted. Fourth, the polarimetric response of the volume hologram is investigated. The polarization study is developed to provide insight into the effect of the refractive index modulation onto the polarization state and diffraction efficiency of incident light.

  9. Volume and Surface-Enhanced Volume Negative Ion Sources

    International Nuclear Information System (INIS)

    Stockli, M P

    2013-01-01

    H - volume sources and, especially, caesiated H - volume sources are important ion sources for generating high-intensity proton beams, which then in turn generate large quantities of other particles. This chapter discusses the physics and technology of the volume production and the caesium-enhanced (surface) production of H - ions. Starting with Bacal's discovery of the H - volume production, the chapter briefly recounts the development of some H - sources, which capitalized on this process to significantly increase the production of H - beams. Another significant increase was achieved in the 1990s by adding caesiated surfaces to supplement the volume-produced ions with surface-produced ions, as illustrated with other H - sources. Finally, the focus turns to some of the experience gained when such a source was successfully ramped up in H - output and in duty factor to support the generation of 1 MW proton beams for the Spallation Neutron Source. (author)

  10. Integrated hollow microneedle-optofluidic biosensor for therapeutic drug monitoring in sub-nanoliter volumes

    Science.gov (United States)

    Ranamukhaarachchi, Sahan A.; Padeste, Celestino; Dübner, Matthias; Häfeli, Urs O.; Stoeber, Boris; Cadarso, Victor J.

    2016-07-01

    Therapeutic drug monitoring (TDM) typically requires painful blood drawn from patients. We propose a painless and minimally-invasive alternative for TDM using hollow microneedles suitable to extract extremely small volumes (microneedle is functionalized to be used as a micro-reactor during sample collection to trap and bind target drug candidates during extraction, without requirements of sample transfer. An optofluidic device is integrated with this microneedle to rapidly quantify drug analytes with high sensitivity using a straightforward absorbance scheme. Vancomycin is currently detected by using volumes ranging between 50-100 μL with a limit of detection (LoD) of 1.35 μM. The proposed microneedle-optofluidic biosensor can detect vancomycin with a sample volume of 0.6 nL and a LoD of <100 nM, validating this painless point of care system with significant potential to reduce healthcare costs and patients suffering.

  11. The effect of water volume and mixing time on physical properties of bread made from modified cassava starch-wheat composite flour

    Science.gov (United States)

    Srirejeki, S.; Manuhara, G. J.; Amanto, B. S.; Atmaka, W.; Laksono, P. W.

    2018-03-01

    Modification of cassava starch with soaking in the whey (by product on cheese production) resulted in changes of the flour characteristics. Adjustments of processing condition are important to be studied in the making of bread from modified cassava starch and wheat composite flour (30:70). This research aims to determine the effect of water volume and mixing time on the physical properties of the bread. The experimental design of this research was Completely Randomized Factorial Design (CRFD) with two factors which were water volume and mixing time. The variation of water volume significantly affected on bread height, dough volume, dough specific volume, and crust thickness. The variation of mixing time had a significant effect on the increase of dough volume and dough specific volume. The combination of water volume and mixing time had a significant effect on dough height, bread volume, bread specific volume, baking expansion, and weight loss.

  12. Ground-water monitoring compliance projects for Hanford site facilities: Progress report for the period, January 1-March 31, 1988: Volume 6, Appendix (contd)

    International Nuclear Information System (INIS)

    1988-05-01

    This appendix is one of nine volumes, and presents data describing wells completed at the Hanford Site during the fourth quarter of calendar year 1987 (October through December). The data in this volume of Appendix B cover the following wells: 299-W7-5; 299-W7-6; 299-W8-1; 299-W9-1; 299-W10-13. The data are presented in the following order: Well Completion Report/Title III Inspection List, Inspection Plan, As-Built Diagram, Logging Charts, and Drill Logs

  13. Just-in-Time Training for High-Risk Low-Volume Therapies: An Approach to Ensure Patient Safety.

    Science.gov (United States)

    Helman, Stephanie; Lisanti, Amy Jo; Adams, Ann; Field, Cynthia; Davis, Katherine Finn

    2016-01-01

    High-risk low-volume therapies are those therapies that are practiced infrequently and yet carry an increased risk to patients because of their complexity. Staff nurses are required to competently manage these therapies to treat patients' unique needs and optimize outcomes; however, maintaining competence is challenging. This article describes implementation of Just-in-Time Training, which requires validation of minimum competency of bedside nurses managing high-risk low-volume therapies through direct observation of a return-demonstration competency checklist.

  14. A meta-analysis of randomized controlled trials of low-volume polyethylene glycol plus ascorbic acid versus standard-volume polyethylene glycol solution as bowel preparations for colonoscopy.

    Directory of Open Access Journals (Sweden)

    Qingsong Xie

    Full Text Available BACKGROUND: Standard-volume polyethylene glycol (PEG gut lavage solutions are safe and effective, but they require the consumption of large volumes of fluid. A new lower-volume solution of PEG plus ascorbic acid has been used recently as a preparation for colonoscopy. AIM: A meta-analysis was performed to compare the performance of low-volume PEG plus ascorbic acid with standard-volume PEG as bowel preparation for colonoscopy. STUDY: Electronic and manual searches were performed to identify randomized controlled trials (RCTs that compared the performance of low-volume PEG plus ascorbic acid with standard-volume PEG as bowel preparation for colonoscopy. After a methodological quality assessment and data extraction, the pooled estimates of bowel preparation efficacy during bowel cleansing, compliance with preparation, willingness to repeat the same preparation, and the side effects were calculated. We calculated pooled estimates of odds ratios (OR by fixed- and/or random-effects models. We also assessed heterogeneity among studies and the publication bias. RESULTS: Eleven RCTs were identified for analysis. The pooled OR for preparation efficacy during bowel cleansing and for compliance with preparation for low-volume PEG plus ascorbic acid were 1.08 (95% CI = 0.98-1.28, P = 0.34 and 2.23 (95% CI = 1.67-2.98, P<0.00001, respectively, compared with those for standard-volume PEG. The side effects of vomiting and nausea for low-volume PEG plus ascorbic acid were reduced relative to standard-volume PEG. There was no significant publication bias, according to a funnel plot. CONCLUSIONS: Low-volume PEG plus ascorbic acid gut lavage achieved non-inferior efficacy for bowel cleansing, is more acceptable to patients, and has fewer side effects than standard-volume PEG as a bowel preparation method for colonoscopy.

  15. Development of Automatic Visceral Fat Volume Calculation Software for CT Volume Data

    Directory of Open Access Journals (Sweden)

    Mitsutaka Nemoto

    2014-01-01

    Full Text Available Objective. To develop automatic visceral fat volume calculation software for computed tomography (CT volume data and to evaluate its feasibility. Methods. A total of 24 sets of whole-body CT volume data and anthropometric measurements were obtained, with three sets for each of four BMI categories (under 20, 20 to 25, 25 to 30, and over 30 in both sexes. True visceral fat volumes were defined on the basis of manual segmentation of the whole-body CT volume data by an experienced radiologist. Software to automatically calculate visceral fat volumes was developed using a region segmentation technique based on morphological analysis with CT value threshold. Automatically calculated visceral fat volumes were evaluated in terms of the correlation coefficient with the true volumes and the error relative to the true volume. Results. Automatic visceral fat volume calculation results of all 24 data sets were obtained successfully and the average calculation time was 252.7 seconds/case. The correlation coefficients between the true visceral fat volume and the automatically calculated visceral fat volume were over 0.999. Conclusions. The newly developed software is feasible for calculating visceral fat volumes in a reasonable time and was proved to have high accuracy.

  16. Newtonian potential and geodesic completeness in infinite derivative gravity

    Science.gov (United States)

    Edholm, James; Conroy, Aindriú

    2017-08-01

    Recent study has shown that a nonsingular oscillating potential—a feature of infinite derivative gravity theories—matches current experimental data better than the standard General Relativity potential. In this work, we show that this nonsingular oscillating potential can be given by a wider class of theories which allows the defocusing of null rays and therefore geodesic completeness. We consolidate the conditions whereby null geodesic congruences may be made past complete, via the Raychaudhuri equation, with the requirement of a nonsingular Newtonian potential in an infinite derivative gravity theory. In doing so, we examine a class of Newtonian potentials characterized by an additional degree of freedom in the scalar propagator, which returns the familiar potential of General Relativity at large distances.

  17. LLE Review Quarterly Report (July-September 1998). Volume 76

    Energy Technology Data Exchange (ETDEWEB)

    Epstein, Reuben [Univ. of Rochester, NY (United States). Lab. for Laser Energetics

    1998-09-01

    This volume of the LLE Review, covering the period July-September 1998, includes reports on two of the newest subsystems in the OMEGA laser facility. A. V. Okishev, M. D. Skeldon, and W. Seka have developed a highly stable, diode-pumped Nd:YLF master oscillator for the OMEGA laser system. This new master oscillator produces either single-frequency Q-switched pulses or cw radiation for the OMEGA pulse-shaping system. The switch-over between these two regimes requires no laser realignment. The new master oscillator is completely computer controlled and has been operating continuously in OMEGA for six months without operator intervention. A. Babushkin, W. Bittle, S. A. Letzring, M. D. Skeldon, and W. Seka have designed a negative-feedback–controlled regenerative amplifier that has been part of the OMEGA laser system for the past two years. The negative feedback makes the energy output of the regenerative amplifier stable and insensitive to the variations in pulse energy. This amplifier’s long-term output energy stability is the highest ever demonstrated for a millijoule-level laser system, either flashlamp pumped or diode pumped. Other articles in this volume are titled: Transcient Bandwidth Analysis of Photoconductive Microwave Switches Implemented in the OMEGA Pulse-Shaping System; Simulations of Near-Field Intensity Modulations in High-Intensity Laser Beams due to Self- and Cross-Phase Modulation Between Orthogonally Polarized Laser Beams Emerging from a Diamond-Turned KDP Wedge; X-Ray Radiographic System Used to Measure the Evolution of Broadband Imprint in Laser-Driven Planar Targets; Collisionless Damping of Localized Plasma Waves in Laser-Produces Plasmas and Application to Stimulated Raman Scattering in Filaments; LLE's Summer High School Research Program; FY98 Laser Facility Report; and, National Laser Users' Facilty News.

  18. Diversion Path Analysis handbook. Volume 4 (of 4 volumes). Computer Program 2

    International Nuclear Information System (INIS)

    Schleter, J.C.

    1978-11-01

    The FORTRAN IV computer program, DPA Computer Program 2 (DPACP-2) is used to produce tables and statistics on modifications identified when performing a Diversion Path Analysis (DPA) in accord with the methodology given in Volume 1. The program requires 259088 bytes exclusive of the operating system. The data assembled and tabulated by DPACP-2 assist the DPA team in analyzing and evaluating modifications to the plant's safeguards system that would eliminate, or reduce the severity of, vulnerabilities identified by means of the DPA. These vulnerabilities relate to the capability of the plant's material control and material accounting subsystems to indicate diversion of special nuclear material (SNM) by a knowledgeable insider

  19. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 2. Commercial waste forms, packaging and projections for preconceptual repository design studies

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Y/OWI/TM-36/2, ''Commercial Waste Forms, Packaging and Projections for Preconceptual Repository Design Studies,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This volume contains the data base for waste forms, packages, and projections from the commercial waste defined by the Office of Waste Isolation in ''Nuclear Waste Projections and Source Term Data for FY 1977,'' Y/OWI/TM-34. Also, as an alternative data base for repository design and analysis, waste forms, packages, and projections for commercial waste defined by Battelle Pacific Northwest Laboratory (BPNL) have been included. This data base consists of a reference case for use in the alternative design study and a definition of combustible wastes for use in mine fire and hydrogen generation analyses

  20. Whole-brain perfusion CT using a toggling table technique to predict final infarct volume in acute ischemic stroke.

    Science.gov (United States)

    Schrader, I; Wilk, D; Jansen, O; Riedel, C

    2013-09-01

    To evaluate how accurately final infarct volume in acute ischemic stroke can be predicted with perfusion CT (PCT) using a 64-MDCT unit and the toggling table technique. Retrospective analysis of 89 patients with acute ischemic stroke who underwent CCT, CT angiography (CTA) and PCT using the "toggling table" technique within the first three hours after symptom onset. In patients with successful thrombolytic therapy (n = 48) and in those without effective thrombolytic therapy (n = 41), the infarct volume and the volume of the penumbra on PCT were compared to the infarct size on follow-up images (CT or MRI) performed within 8 days. The feasibility of complete infarct volume prediction by 8 cm cranio-caudal coverage was evaluated. The correlation between the volume of hypoperfusion on PCT defined by cerebral blood volume reduction and final infarct volume was strongest in patients with successful thrombolytic therapy with underestimation of the definite infarct volume by 8.5 ml on average. The CBV map had the greatest prognostic value. In patients without successful thrombolytic therapy, the final infarct volume was overestimated by 12.1 ml compared to the MTT map on PCT. All infarcts were detected completely. There were no false-positive or false-negative results. Using PCT and the "toggling table" technique in acute stroke patients is helpful for the rapid and accurate quantification of the minimal final infarct and is therefore a prognostic parameter which has to be evaluated in further studies to assess its impact on therapeutic decision. ▶ Using PCT and the “toggling table technique” allows accurate quantification of the infarct core and penumbra. ▶ It is possible to record dynamic perfusion parameters quickly and easily of almost the entire supratentorial brain volume on a 64-slice MDCT unit. ▶ The technique allows identification of those patients who could profit from thrombolytic therapy outside the established time intervals. © Georg Thieme Verlag

  1. FURTHER STUDIES ON THE VARIATION OF SPRAY DEPOSITS IN VINEYARDS WITH AIRFLOW RATE AND VOLUME RATE

    Directory of Open Access Journals (Sweden)

    Emanuele Cerruto

    2007-03-01

    Full Text Available The present research, continuing that reported in [2], deals with the spray application subject, so to investigate as volume rate and airflow rate, forward speed being equal, affect the foliar deposition in an espalier vineyard. Experimental trials were carried out by means of an air assisted towed sprayer, equipped with “Albuz ATR” nozzles. To take into account the influence of the development of the trees, the field trials were replicated in two phenological stages with an interval of about one month: “Inflorescences fully developed” (stage 1 and “Beginning of berry touch” (stage 2. A full factorial experiment was carried out for each growth stage, with two airflow rates (3.9 and 7.5 m3/s, three volume rates (103, 216, and 276 L/ha in the first growth stage and 154, 330 and 432 L/ha in the second growth stage, and four replicates, arranged according to a randomised complete block design. Working pressure (1.2 MPa and forward speed (1.4 m/s were kept unchanged for all the trials. The foliar deposition was measured by means of a spectrophotometric technique. The leaves were sampled on two depth layers and two or three heights, according to the trees’ development. The results showed that volume rate did not significantly influence the mean foliar deposition in both the two growth stages, while the highest deposits were obtained with the lowest airflow rate. The airflow rate × volume rate interaction, though not statistically significant, showed that low volume rates together with high airflow rates, result in a noticeable reduction in foliar deposition (29% with respect the grand mean, due to an increase of the spry drift, especially at the first growth stage, when the foliar development is little. These second tests, unlike those described in [2], did not show any positive influence of the airflow rate on the foliar deposition in the inner part of the canopy, so further investigations could be necessary to better understand the

  2. Change in Seroma Volume During Whole-Breast Radiation Therapy

    International Nuclear Information System (INIS)

    Sharma, Rajiv; Spierer, Marnee; Mutyala, Subhakar; Thawani, Nitika; Cohen, Hillel W.; Hong, Linda; Garg, Madhur K.; Kalnicki, Shalom

    2009-01-01

    Purpose: After breast-conserving surgery, a seroma often forms in the surgical cavity. If not drained, it may affect the volume of tumor bed requiring a boost after whole-breast radiation therapy (WBRT). Our objective was to evaluate the change in seroma volume that occurs during WBRT, before boost planning. Methods and Materials: A retrospective review was performed of women receiving breast-conserving therapy with evidence of seroma at the time of WBRT planning. Computed tomography (CT) simulation was performed before WBRT and before the tumor bed boost. All patients received either a hypofractionated (42.4 Gy/16 fraction + 9.6 Gy/4 fraction boost) or standard fractionated (50.4 Gy/28 fraction + 10 Gy/5 fraction boost) regimen. Seroma volumes were contoured and compared on CT at the time of WBRT simulation and tumor bed boost planning. Results: Twenty-four patients with evidence of seroma were identified and all patients received WBRT without drainage of the seroma. Mean seroma volume before WBRT and at boost planning were significantly different at 65.7 cm 3 (SD, 50.5 cm 3 ) and 35.6 cm 3 (SD, 24.8 cm 3 ), respectively (p < 0.001). Mean and median reduction in seroma volume during radiation were 39.6% (SD, 23.8%) and 46.2% (range, 10.7-76.7%), respectively. Fractionation schedule was not correlated with change in seroma volume. Length of time from surgery to start of radiation therapy showed an inverse correlation with change in seroma volume (Pearson correlation r = -0.53, p < 0.01). Conclusions: The volume of seroma changes significantly during WBRT. Consequently, the accuracy of breast boost planning is likely affected, as is the volume of normal breast tissue irradiated. CT-based boost planning before boost irradiation is suggested to ensure appropriate coverage.

  3. Results of completion arteriography after minimally invasive off-pump coronary artery bypass.

    Science.gov (United States)

    Hoff, Steven J; Ball, Stephen K; Leacche, Marzia; Solenkova, Natalia; Umakanthan, Ramanan; Petracek, Michael R; Ahmad, Rashid; Greelish, James P; Walker, Kristie; Byrne, John G

    2011-01-01

    The benefits of a minimally invasive approach to off-pump coronary artery bypass remain controversial. The value of completion arteriography in validating this technique has not been investigated. From April 2007 to October 2009, fifty-six patients underwent isolated minimally invasive coronary artery bypass grafting through a left thoracotomy without cardiopulmonary bypass. Forty-three of these patients underwent completion arteriography. Sixty-five grafts were performed in these 56 patients, (average, 1.2 grafts per patient; range, 1 to 3). Forty-eight grafts were studied in the 43 patients undergoing completion arteriography. There were 4 findings on arteriogram leading to further immediate intervention (8.3%). These included 3 grafts with anastomotic stenoses or spasm requiring stent placement, and 1 patient who had limited dissection in the left internal mammary artery graft and underwent placement of an additional vein graft. These findings were independent of electrocardiographic changes or hemodynamic instability. The remainder of the studies showed no significant abnormalities. There were no deaths. One patient who did not have a completion arteriogram suffered a postoperative myocardial infarction requiring stent placement for anastomotic stenosis. Patients were discharged home an average of 6.8 days postoperatively. There were no instances of renal dysfunction postoperatively attributable to catheterization. Minimally invasive coronary artery bypass is safe and effective. Findings of completion arteriography occasionally reveal previously under-recognized findings that, if corrected in a timely fashion, could potentially impact graft patency and clinical outcomes. Our experience validates this minimally invasive technique. Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  4. Effect of water volume based on water absorption and mixing time on physical properties of tapioca starch – wheat composite bread

    Science.gov (United States)

    Prameswari, I. K.; Manuhara, G. J.; Amanto, B. S.; Atmaka, W.

    2018-05-01

    Tapioca starch application in bread processing change water absorption level by the dough, while sufficient mixing time makes the optimal water absorption. This research aims to determine the effect of variations in water volume and mixing time on physical properties of tapioca starch – wheat composite bread and the best method for the composite bread processing. This research used Complete Randomized Factorial Design (CRFD) with two factors: variations of water volume (111,8 ml, 117,4 ml, 123 ml) and mixing time (16 minutes, 17 minutes 36 seconds, 19 minutes 12 seconds). The result showed that water volume significantly affected on dough volume, bread volume and specific volume, baking expansion, and crust thickness. Mixing time significantly affected on dough volume and specific volume, bread volume and specific volume, baking expansion, bread height, and crust thickness. While the combination of water volume and mixing time significantly affected for all physical properties parameters except crust thickness.

  5. A novel technique for investigation of complete and partial anisotropic wetting on structured surface by X-ray microtomography

    Energy Technology Data Exchange (ETDEWEB)

    Santini, M., E-mail: maurizio.santini@unibg.it [Department of Engineering and Applied Sciences, University of Bergamo, Bergamo (Italy); Guilizzoni, M. [Department of Energy, Politecnico di Milano, Milano (Italy); Fest-Santini, S. [Department of Engineering, University of Bergamo, Bergamo (Italy); Lorenzi, M. [School of Engineering and Mathematical Sciences, City University London, London (United Kingdom)

    2015-02-15

    An experimental study about the anisotropic wetting behavior of a surface patterned with parallel grooves is presented as an application example of a novel technique for investigation of complete and partial anisotropic wetting on structured surface by X-ray microtomography. Shape of glycerin droplets on such surface is investigated by X-ray micro computed tomography (microCT) acting as a non-intrusive, full volume 3D microscope with micrometric spatial resolution. The reconstructed drop volumes enable to estimate the exact volumes of the drops, their base contours, and 3D static contact angles, based on true cross-sections of the drop-surface couple. Droplet base contours are compared to approximate geometrical contour shapes proposed in the literature. Contact angles along slices parallel and perpendicular to the grooves direction are compared with each other. The effect of the sessile drop volume on the wetting behavior is discussed. The proposed technique, which is applicable for any structured surface, enables the direct measure of Wenzel ratio based on the microCT scan in the wetted region usually inapproachable by any others. Comparisons with simplified models are presented and congruence of results with respect to the minimum resolution needed is evaluated and commented.

  6. Optimized Planning Target Volume for Intact Cervical Cancer

    International Nuclear Information System (INIS)

    Khan, Alvin; Jensen, Lindsay G.; Sun Shuai; Song, William Y.; Yashar, Catheryn M.; Mundt, Arno J.; Zhang Fuquan; Jiang, Steve B.; Mell, Loren K.

    2012-01-01

    Purpose: To model interfraction clinical target volume (CTV) variation in patients with intact cervical cancer and design a planning target volume (PTV) that minimizes normal tissue dose while maximizing CTV coverage. Methods and Materials: We analyzed 50 patients undergoing external-beam radiotherapy for intact cervical cancer using daily online cone-beam computed tomography (CBCT). The CBCTs (n = 972) for each patient were rigidly registered to the planning CT. The CTV was delineated on the planning CT (CTV 0 ) and the set of CBCTs ({CTV 1 –CTV 25 }). Manual (n = 98) and automated (n = 668) landmarks were placed over the surface of CTV 0 with reference to defined anatomic structures. Normal vectors were extended from each landmark, and the minimum length required for a given probability of encompassing CTV 1 –CTV 25 was computed. The resulting expansions were used to generate an optimized PTV. Results: The mean (SD; range) normal vector length to ensure 95% coverage was 4.3 mm (2.7 mm; 1–16 mm). The uniform expansion required to ensure 95% probability of CTV coverage was 13 mm. An anisotropic margin of 20 mm anteriorly and posteriorly and 10 mm superiorly, inferiorly, and laterally also would have ensured a 95% probability of CTV coverage. The volume of the 95% optimized PTV (1470 cm 3 ) was significantly lower than both the anisotropic PTV (2220 cm 3 ) and the uniformly expanded PTV (2110 cm 3 ) (p 0 , 5–10 mm along the interfaces of CTV 0 with the bladder and rectum, and 10–14 mm along the anterior surface of CTV 0 at the level of the uterus. Conclusion: Optimizing PTV definition according to surface landmarking resulted in a high probability of CTV coverage with reduced PTV volumes. Our results provide data justifying planning margins to use in practice and clinical trials.

  7. A rapid method for estimation of Pu-isotopes in urine samples using high volume centrifuge.

    Science.gov (United States)

    Kumar, Ranjeet; Rao, D D; Dubla, Rupali; Yadav, J R

    2017-07-01

    The conventional radio-analytical technique used for estimation of Pu-isotopes in urine samples involves anion exchange/TEVA column separation followed by alpha spectrometry. This sequence of analysis consumes nearly 3-4 days for completion. Many a times excreta analysis results are required urgently, particularly under repeat and incidental/emergency situations. Therefore, there is need to reduce the analysis time for the estimation of Pu-isotopes in bioassay samples. This paper gives the details of standardization of a rapid method for estimation of Pu-isotopes in urine samples using multi-purpose centrifuge, TEVA resin followed by alpha spectrometry. The rapid method involves oxidation of urine samples, co-precipitation of plutonium along with calcium phosphate followed by sample preparation using high volume centrifuge and separation of Pu using TEVA resin. Pu-fraction was electrodeposited and activity estimated using 236 Pu tracer recovery by alpha spectrometry. Ten routine urine samples of radiation workers were analyzed and consistent radiochemical tracer recovery was obtained in the range 47-88% with a mean and standard deviation of 64.4% and 11.3% respectively. With this newly standardized technique, the whole analytical procedure is completed within 9h (one working day hour). Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Guidance and Control Software Project Data - Volume 4: Configuration Management and Quality Assurance Documents

    Science.gov (United States)

    Hayhurst, Kelly J. (Editor)

    2008-01-01

    The Guidance and Control Software (GCS) project was the last in a series of software reliability studies conducted at Langley Research Center between 1977 and 1994. The technical results of the GCS project were recorded after the experiment was completed. Some of the support documentation produced as part of the experiment, however, is serving an unexpected role far beyond its original project context. Some of the software used as part of the GCS project was developed to conform to the RTCA/DO-178B software standard, "Software Considerations in Airborne Systems and Equipment Certification," used in the civil aviation industry. That standard requires extensive documentation throughout the software development life cycle, including plans, software requirements, design and source code, verification cases and results, and configuration management and quality control data. The project documentation that includes this information is open for public scrutiny without the legal or safety implications associated with comparable data from an avionics manufacturer. This public availability has afforded an opportunity to use the GCS project documents for DO-178B training. This report provides a brief overview of the GCS project, describes the 4-volume set of documents and the role they are playing in training, and includes configuration management and quality assurance documents from the GCS project. Volume 4 contains six appendices: A. Software Accomplishment Summary for the Guidance and Control Software Project; B. Software Configuration Index for the Guidance and Control Software Project; C. Configuration Management Records for the Guidance and Control Software Project; D. Software Quality Assurance Records for the Guidance and Control Software Project; E. Problem Report for the Pluto Implementation of the Guidance and Control Software Project; and F. Support Documentation Change Reports for the Guidance and Control Software Project.

  9. Waste retrieval sluicing system campaign number 1 solids volume transferred calculation

    International Nuclear Information System (INIS)

    BAILEY, J.W.

    1999-01-01

    This calculation has been prepared to document the volume of sludge removed from tank 241-C-106 during Waste Retrieval Sluicing System (WRSS) Sluicing Campaign No.1. This calculation will be updated, if necessary, to incorporate new data. This calculation supports the declaration of completion of WRSS Campaign No.1 and, as such, is also the documentation for completion of Performance Agreement TWR 1.2.1 , C-106 Sluicing Performance Expectations. It documents the performance of all the appropriate tank 241-C-106 mass transfer verifications, evaluations, and appropriate adjustments discussed in HNF-SD-WM-PROC-021, Chapter 23, ''Process Engineering Calculations for Tank 241-C-106 Sluicing and Retrieval''

  10. Waste retrieval sluicing system campaign number 1 solids volume transferred calculation

    International Nuclear Information System (INIS)

    BAILEY, J.W.

    1999-01-01

    This calculation has been prepared to document the volume of sludge removed from tank 241-C-106 during Waste Retrieval Sluicing System (WRSS) Sluicing Campaign No.1. This calculation will be updated, if necessary, to incorporate new data. This calculation supports the declaration of completion of WRSS Campaign No.1 and, as such, is also the documentation for completion of Performance Agreement TWR 1.2.1 C-106 Sluicing Performance Expectations. It documents the performance of all the appropriate tank 241-C-106 mass transfer verifications, evaluations, and appropriate adjustments discussed in HNF-SD-WM-PROC-021, Chapter 23, ''Process Engineering Calculations for Tank 241-C-106 Sluicing and Retrieval''

  11. Detection of the Single-Session Complete Ablation Rate by Contrast-Enhanced Ultrasound during Ultrasound-Guided Laser Ablation for Benign Thyroid Nodules: A Prospective Study

    Directory of Open Access Journals (Sweden)

    Shuhua Ma

    2016-01-01

    Full Text Available This study aimed to investigate the single-session complete ablation rate of ultrasound-guided percutaneous laser ablation (LA for benign thyroid nodules. LA was performed in 90 patients with 118 benign thyroid nodules. Contrast-enhanced ultrasound (CEUS was used to evaluate complete nodule ablation one day after ablation. Thyroid nodule volumes, thyroid functions, clinical symptoms and complications were evaluated 1, 3, 6, 12, and 18 months after ablation. Results showed that all benign thyroid nodules successfully underwent LA. The single-session complete ablation rates for nodules with maximum diameters ≤2 cm, 2-3 cm and ≥3 cm were 93.4%, 70.3% and 61.1%, respectively. All nodule volumes significantly decreased than that one day after ablation (P0.05. Three patients had obvious pain during ablation; one (1.1% had recurrent laryngeal nerve injury, but the voice returned to normal within 6 months after treatment. Thus, ultrasound-guided LA can effectively inactivate benign thyroid nodules. LA is a potentially viable minimally invasive treatment that offers good cosmetic effects.

  12. Accuracy of Digitally Fabricated Wax Denture Bases and Conventional Completed Complete Dentures

    Directory of Open Access Journals (Sweden)

    Bogna Stawarczyk

    2017-12-01

    Full Text Available The purpose of this investigation was to analyze the accuracy of digitally fabricated wax trial dentures and conventionally finalized complete dentures in comparison to a surface tessellation language (STL-dataset. A generated data set for the denture bases and the tooth sockets was used, converted into STL-format, and saved as reference. Five mandibular and 5 maxillary denture bases were milled from wax blanks and denture teeth were waxed into their tooth sockets. Each complete denture was checked on fit, waxed onto the dental cast, and digitized using an optical laboratory scanning device. The complete dentures were completed conventionally using the injection method, finished, and scanned. The resulting STL-datasets were exported into the three-dimensional (3D software GOM Inspect. Each of the 5 mandibular and 5 maxillary complete dentures was aligned with the STL- and the wax trial denture dataset. Alignment was performed based on a best-fit algorithm. A three-dimensional analysis of the spatial divergences in x-, y- and z-axes was performed by the 3D software and visualized in a color-coded illustration. The mean positive and negative deviations between the datasets were calculated automatically. In a direct comparison between maxillary wax trial dentures and complete dentures, complete dentures showed higher deviations from the STL-dataset than the wax trial dentures. The deviations occurred in the area of the teeth as well as in the distal area of the denture bases. In contrast, the highest deviations in both the mandibular wax trial dentures and the mandibular complete dentures were observed in the distal area. The complete dentures showed higher deviations on the occlusal surfaces of the teeth compared to the wax dentures. Computer-aided design/computer-aided manufacturing (CAD/CAM-fabricated wax dentures exhibited fewer deviations from the STL-reference than the complete dentures. The deviations were significantly greater in the

  13. Helium-induced blistering and volume swelling in nickel

    International Nuclear Information System (INIS)

    Fenske, G.R.

    1979-01-01

    The results of an experimental investigation of He-induced blistering are presented. The mechanisms involved in blistering were examined by observing the microstructure of the implanted region using TEM. The volume swelling was measured as a function of the implant depth. The investigation revealed factors important in understanding the mechanisms involved in blister formation. First, a direct comparison of measured skin-thicknesses with the location of the maximum volume swelling demonstrated that the skin separates at the peak swelling depth, not at the end of the swelling profile. Second, an examination of the assumptions that have been used to predict skin-thicknesses revealed that the differences between predicted and measured skin thicknesses at low energies can be attributed to: failure to account for volume swelling in the skin, using a Gaussian approximation to the range profile, or one generated with a Monte-Carlo code, and uncertainties in the electronic stopping powers. Beyond a certain dose, the density of cavities in the peak-swelling region decreased with increasing dose; indicating that cavity coalescence does occur. A calculation of the He concentration required to fracture the load-bearing cross section between the cavities revealed that a sufficient quantity of He was available to generate the required gas pressures. These observations indicate that models based on coalescence followed by gas-driven deformation provide an accurate description of the mechanisms involved in blistering; and they can accurately predict skin thicknesses at low energies

  14. Additive Cellular Automata and Volume Growth

    Directory of Open Access Journals (Sweden)

    Thomas B. Ward

    2000-08-01

    Full Text Available Abstract: A class of dynamical systems associated to rings of S-integers in rational function fields is described. General results about these systems give a rather complete description of the well-known dynamics in one-dimensional additive cellular automata with prime alphabet, including simple formulæ for the topological entropy and the number of periodic configurations. For these systems the periodic points are uniformly distributed along some subsequence with respect to the maximal measure, and in particular are dense. Periodic points may be constructed arbitrarily close to a given configuration, and rationality of the dynamical zeta function is characterized. Throughout the emphasis is to place this particular family of cellular automata into the wider context of S-integer dynamical systems, and to show how the arithmetic of rational function fields determines their behaviour. Using a covering space the dynamics of additive cellular automata are related to a form of hyperbolicity in completions of rational function fields. This expresses the topological entropy of the automata directly in terms of volume growth in the covering space.

  15. Draft Site Treatment Plan (DSTP), Volumes I and II

    International Nuclear Information System (INIS)

    D'Amelio, J.

    1994-01-01

    Site Treatment Plans (STP) are required for facilities at which the DOE generates or stores mixed waste. This Draft Site Treatment Plan (DSTP) the second step in a three-phase process, identifies the currently preferred options for treating mixed waste at the Savannah River Site (SRS) or for developing treatment technologies where technologies do not exist or need modification. The DSTP reflects site-specific preferred options, developed with the state's input and based on existing available information. To the extent possible, the DSTP identifies specific treatment facilities for treating the mixed waste and proposes schedules. Where the selection of specific treatment facilities is not possible, schedules for alternative activities such as waste characterization and technology assessment are provided. All schedule and cost information presented is preliminary and is subject to change. The DSTP is comprised of two volumes: this Compliance Plan Volume and the Background Volume. This Compliance Plan Volume proposes overall schedules with target dates for achieving compliance with the land disposal restrictions (LDR) of RCRA and procedures for converting the target dates into milestones to be enforced under the Order. The more detailed discussion of the options contained in the Background Volume is provided for informational purposes only

  16. Assessing Requirements Quality through Requirements Coverage

    Science.gov (United States)

    Rajan, Ajitha; Heimdahl, Mats; Woodham, Kurt

    2008-01-01

    In model-based development, the development effort is centered around a formal description of the proposed software system the model. This model is derived from some high-level requirements describing the expected behavior of the software. For validation and verification purposes, this model can then be subjected to various types of analysis, for example, completeness and consistency analysis [6], model checking [3], theorem proving [1], and test-case generation [4, 7]. This development paradigm is making rapid inroads in certain industries, e.g., automotive, avionics, space applications, and medical technology. This shift towards model-based development naturally leads to changes in the verification and validation (V&V) process. The model validation problem determining that the model accurately captures the customer's high-level requirements has received little attention and the sufficiency of the validation activities has been largely determined through ad-hoc methods. Since the model serves as the central artifact, its correctness with respect to the users needs is absolutely crucial. In our investigation, we attempt to answer the following two questions with respect to validation (1) Are the requirements sufficiently defined for the system? and (2) How well does the model implement the behaviors specified by the requirements? The second question can be addressed using formal verification. Nevertheless, the size and complexity of many industrial systems make formal verification infeasible even if we have a formal model and formalized requirements. Thus, presently, there is no objective way of answering these two questions. To this end, we propose an approach based on testing that, when given a set of formal requirements, explores the relationship between requirements-based structural test-adequacy coverage and model-based structural test-adequacy coverage. The proposed technique uses requirements coverage metrics defined in [9] on formal high-level software

  17. Estimation of lung volume and pulmonary blood volume from radioisotopic images

    International Nuclear Information System (INIS)

    Kanazawa, Minoru

    1989-01-01

    Lung volume and pulmonary blood volume in man were estimated from the radioisotopic image using single photon emission computed tomography (SPECT). Six healthy volunteers were studied in a supine position with normal and altered lung volumes by applying continuous negative body-surface pressure (CNP) and by positive end-expiratory pressure (PEEP). 99m Tc labeled human serum albumin was administered as an aerosol to image the lungs. The CNP caused the diaphragm to be lowered and it increased the mean lung tissue volume obtained by SPECT from 3.09±0.49 l for baseline to 3.67±0.62 l for 10 cmH 2 O (p 2 O (p 2 O), respectively. The PEEP also increased the lung tissue volume to 3.68±0.68 l for 10 cmH 2 O as compared with the baseline (p 2 O PEEP. The lung tissue volume obtained by SPECT showed a positive correlation with functional residual capacity measured by the He dilution method (r=0.91, p 99m Tc-labeled red blood cells. The L/H ratio decreased after either the CNP or PEEP, suggesting a decrease in the blood volume per unit lung volume. However, it was suggested that the total pulmonary blood volume increased slightly either on the CNP (+7.4% for 10 cmH 2 O, p 2 O,p<0.05) when we extrapolated the L/H ratio to the whole lungs by multiplying the lung tissue volume obtained by SPECT. We concluded that SPECT could offer access to the estimation of lung volume and pulmonary blood volume in vivo. (author)

  18. Influence of sex and age on fasting and post-prandial gallbladder volumes

    International Nuclear Information System (INIS)

    Pazzi, P.; Putinati, S.; Barbieri, D.; Trevisani, L.; Limoni, G.; Lupi, L.; Bighi, S.

    1989-01-01

    Aging and female sex are major risk factors for cholesterol gallstones: in addition to hepatic secretion of lithogenic bile, decreased gallbladder contractility may play a role in such physiological conditions. This study was aimed at evaluating the effect of age and sex on gallbladder kinetics in healthy subjects. Gallbladder volume was measured on the US images of 157 fasting subjects using the sum-of-cylinders method. No significant difference was observed between males and females. On the contrary, age was shown to have a significant positive correlation with fasting gallbladder volume, particulary in males. In a second group of 63 healthy volunteers gallbladder volumes were evaluated both before and after a standard meal. The subjects were grouped according to age, and fasting gallbladder volume appeared to be significantly greater in the groups formed by older people. Gallbladder volumes were compared in younger groups (under 35), and gallbladder emptying resulted to be much more complete in males than in females. On the contrary, no significant differences was observed between males and famales over50 - which suggests a possible role of sex - and age-related hormonal factors. The above changes in gallbladder function may facilitate bile stasis which might in turn contribute to the increased risk for cholesterol gallstones notoriously associated with advanced age and female sex

  19. 5 CFR 575.210 - Service agreement requirements.

    Science.gov (United States)

    2010-01-01

    ... agreement must specify that if an employee does not successfully complete the training before the service... employee. (c) The service agreement must specify the total amount of the incentive, the method of paying... incentive, an agency must require the employee to sign a written service agreement to complete a specified...

  20. Cross-correlations in volume space: Differences between buy and sell volumes

    Science.gov (United States)

    Lee, Sun Young; Hwang, Dong Il; Kim, Min Jae; Koh, In Gyu; Kim, Soo Yong

    2011-03-01

    We study the cross-correlations of buy and sell volumes on the Korean stock market in high frequency. We observe that the pulling effects of volumes are as small as that of returns. The properties of the correlations of buy and sell volumes differ. They are explained by the degree of synchronization of stock volumes. Further, the pulling effects on the minimal spanning tree are studied. In minimal spanning trees with directed links, the large pulling effects are clustered at the center, not uniformly distributed. The Epps effect of buy and sell volumes are observed. The reversal of the cross-correlations of buy and sell volumes is also detected.

  1. Engineering Drawing Practices - Volume I of II: Aerospace and Ground Support Equipment

    Science.gov (United States)

    Schwindt, Paul A.

    2015-01-01

    This manual establishes the essential requirements and reference documents for the preparation and revision of digital product definition data sets prepared for or by NASA at KSC. This volume is only applicable to KSC in-house programs/projects. These requirements do not apply to the preparation of illustrations, artwork, or figures in technical publications.

  2. [Prediction of the efficiency of endoscopic lung volume reduction by valves in severe emphysema].

    Science.gov (United States)

    Bocquillon, V; Briault, A; Reymond, E; Arbib, F; Jankowski, A; Ferretti, G; Pison, C

    2016-11-01

    In severe emphysema, endoscopic lung volume reduction with valves is an alternative to surgery with less morbidity and mortality. In 2015, selection of patients who will respond to this technique is based on emphysema heterogeneity, a complete fissure visible on the CT-scan and absence of collateral ventilation between lobes. Our case report highlights that individualized prediction is possible. A 58-year-old woman had severe, disabling pulmonary emphysema. A high resolution thoracic computed tomography scan showed that the emphysema was heterogeneous, predominantly in the upper lobes, integrity of the left greater fissure and no collateral ventilation with the left lower lobe. A valve was inserted in the left upper lobe bronchus. At one year, clinical and functional benefits were significant with complete atelectasis of the treated lobe. The success of endoscopic lung volume reduction with a valve can be predicted, an example of personalized medicine. Copyright © 2016 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  3. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 16. Repository preconceptual design studies: BPNL waste forms in salt

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Volume 16, ''Repository Preconceptual Design Studies: BPNL Waste Forms in Salt,'' is one of a 23 volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provide a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This document describes a preconceptual design for a nuclear waste storage facility in salt. The waste forms assumed to arrive at the repository were supplied by Battelle Pacific Northwest Laboratories (BPNL). The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/17, ''Drawings for Repository Preconceptual Design Studies: BPNL Waste Forms in Salt.''

  4. Emergent Chemical Behavior in Variable-Volume Protocells

    Directory of Open Access Journals (Sweden)

    Ben Shirt-Ediss

    2015-01-01

    Full Text Available Artificial protocellular compartments and lipid vesicles have been used as model systems to understand the origins and requirements for early cells, as well as to design encapsulated reactors for biotechnology. One prominent feature of vesicles is the semi-permeable nature of their membranes, able to support passive diffusion of individual solute species into/out of the compartment, in addition to an osmotic water flow in the opposite direction to the net solute concentration gradient. Crucially, this water flow affects the internal aqueous volume of the vesicle in response to osmotic imbalances, in particular those created by ongoing reactions within the system. In this theoretical study, we pay attention to this often overlooked aspect and show, via the use of a simple semi-spatial vesicle reactor model, that a changing solvent volume introduces interesting non-linearities into an encapsulated chemistry. Focusing on bistability, we demonstrate how a changing volume compartment can degenerate existing bistable reactions, but also promote emergent bistability from very simple reactions, which are not bistable in bulk conditions. One particularly remarkable effect is that two or more chemically-independent reactions, with mutually exclusive reaction kinetics, are able to couple their dynamics through the variation of solvent volume inside the vesicle. Our results suggest that other chemical innovations should be expected when more realistic and active properties of protocellular compartments are taken into account.

  5. The plant cytoskeleton controls regulatory volume increase.

    Science.gov (United States)

    Liu, Qiong; Qiao, Fei; Ismail, Ahmed; Chang, Xiaoli; Nick, Peter

    2013-09-01

    The ability to adjust cell volume is required for the adaptation to osmotic stress. Plant protoplasts can swell within seconds in response to hypoosmotic shock suggesting that membrane material is released from internal stores. Since the stability of plant membranes depends on submembraneous actin, we asked, whether this regulatory volume control depends on the cytoskeleton. As system we used two cell lines from grapevine which differ in their osmotic tolerance and observed that the cytoskeleton responded differently in these two cell lines. To quantify the ability for regulatory volume control, we used hydraulic conductivity (Lp) as readout and demonstrated a role of the cytoskeleton in protoplast swelling. Chelation of calcium, inhibition of calcium channels, or manipulation of membrane fluidity, did not significantly alter Lp, whereas direct manipulation of the cytoskeleton via specific chemical reagents, or indirectly, through the bacterial elicitor Harpin or activation of phospholipase D, was effective. By optochemical engineering of actin using a caged form of the phytohormone auxin we can break the symmetry of actin organisation resulting in a localised deformation of cell shape indicative of a locally increased Lp. We interpret our findings in terms of a model, where the submembraneous cytoskeleton controls the release of intracellular membrane stores during regulatory volume change. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Preliminary thermal and thermomechanical modeling for the near surface test facility heater experiments at Hanford. Volume II: Appendix D

    International Nuclear Information System (INIS)

    Chan, T.; Remer, J.S.

    1978-12-01

    Appendix D is a complete set of figures illustrating the detailed calculations necessary for designing the heater experiments at the Near Surface Test Facility (NSTF) at Hanford, Washington. The discussion of the thermal and thermomechanical modeling that yielded these calculations is presented in Volume 1. A summary of the figures and the models they illustrate is given in table D1. The most important figures have also been included in the discussion in Volume 1, and Table D2 lists the figure numbers in this volume that correspond to figure numbers used there

  7. Ground-water monitoring compliance projects for Hanford site facilities: Progress report for the period January 1 to March 31, 1988: Volume 5, Appendix B

    Energy Technology Data Exchange (ETDEWEB)

    None

    1988-05-01

    This appendix is one of nine volumes, and presents data describing wells completed at the Hanford Site during the fourth quarter of calendar year 1987 (October through December). The data in this volume of Appendix B cover the following wells: 299-W6-2; 299-W7-1; 299-W7-2; 299-W7-3; 299-W7-4. The data are presented in the following order: Well Completion Report/Title III Inspection List, Inspection Plan, As-Built Diagram, Logging Charts, and Drill Logs.

  8. Ground-water monitoring compliance projects for Hanford site facilities: Progress report for the period, January 1-March 31, 1988: Volume 6, Appendix B (contd)

    Energy Technology Data Exchange (ETDEWEB)

    1988-05-01

    This appendix is one of nine volumes, and presents data describing wells completed at the Hanford Site during the fourth quarter of calendar year 1987 (October through December). The data in this volume of Appendix B cover the following wells: 299-W7-5; 299-W7-6; 299-W8-1; 299-W9-1; 299-W10-13. The data are presented in the following order: Well Completion Report/Title III Inspection List, Inspection Plan, As-Built Diagram, Logging Charts, and Drill Logs.

  9. Corporate Data Network (CDN) data requirements task. Enterprise Model. Volume 1

    International Nuclear Information System (INIS)

    1985-11-01

    The NRC has initiated a multi-year program to centralize its information processing in a Corporate Data Network (CDN). The new information processing environment will include shared databases, telecommunications, office automation tools, and state-of-the-art software. Touche Ross and Company was contracted with to perform a general data requirements analysis for shared databases and to develop a preliminary plan for implementation of the CDN concept. The Enterprise Model (Vol. 1) provided the NRC with agency-wide information requirements in the form of data entities and organizational demand patterns as the basis for clustering the entities into logical groups. The Data Dictionary (Vol. 2) provided the NRC with definitions and example attributes and properties for each entity. The Data Model (Vol. 3) defined logical databases and entity relationships within and between databases. The Preliminary Strategic Data Plan (Vol. 4) prioritized the development of databases and included a workplan and approach for implementation of the shared database component of the Corporate Data Network

  10. Optimal transformation for correcting partial volume averaging effects in magnetic resonance imaging

    International Nuclear Information System (INIS)

    Soltanian-Zadeh, H.; Windham, J.P.; Yagle, A.E.

    1993-01-01

    Segmentation of a feature of interest while correcting for partial volume averaging effects is a major tool for identification of hidden abnormalities, fast and accurate volume calculation, and three-dimensional visualization in the field of magnetic resonance imaging (MRI). The authors present the optimal transformation for simultaneous segmentation of a desired feature and correction of partial volume averaging effects, while maximizing the signal-to-noise ratio (SNR) of the desired feature. It is proved that correction of partial volume averaging effects requires the removal of the interfering features from the scene. It is also proved that correction of partial volume averaging effects can be achieved merely by a linear transformation. It is finally shown that the optimal transformation matrix is easily obtained using the Gram-Schmidt orthogonalization procedure, which is numerically stable. Applications of the technique to MRI simulation, phantom, and brain images are shown. They show that in all cases the desired feature is segmented from the interfering features and partial volume information is visualized in the resulting transformed images

  11. Psychological stress moderates the relationship between running volume and CD4+ T cell subpopulations.

    Science.gov (United States)

    Rehm, K E; Sunesara, I; Tull, M T; Marshall, G D

    2016-01-01

    Endurance-based exercise training can lead to alterations in components of the immune system, but it is unknown how psychological stress (another potent immunomodulator) may impact these changes. The purpose of this study was to determine the moderating role of psychological stress on exercise-induced immune changes. Twenty-nine recreational runners were recruited for this study four weeks before completing a marathon. Each subject reported: weekly training volume (miles/wk) for the week prior to the study visit; completed the Perceived Stress Scale (PSS), the state version of the State-Trait Anxiety Inventory (STAI) and the Penn State Worry Questionnaire (PSWQ); and donated blood for assessment of CD4+ T cell subpopulations and mitogen-induced cytokine production. Participants ran an average of 30 (±13.4) miles (1 mile=1.6 km) per week. Average values (SD) for immune biomarkers were: regulatory T cells (Treg), 3.2% (±1.2%); type 1 regulatory cells (Tr1), 27.1% (±8.3%); T helper 3 (Th3), 1.8% (±0.7%); interferon gamma (IFNγ), 3.1 pg/ml (±1.0); interleukin (IL)-4, 1.4 pg/ml (±1.1); IFNγ/IL-4, 8.6 (±1.2); IL-10, 512 pg/ml (±288). There was a significant relationship between running volume and both Treg cell numbers (slope of the regression line (β)=0.05, p less than 0.001) and IL-10 production β=-10.6, p=0.002), and there was a trending relationship between running volume and Tr1 cell numbers (β=-0.2%, p=0.064). Perceived stress was a trending moderator of the running volume-Treg relationship, whereas worry was a significant moderator of the running volume-IFNγ and running volume-IFNγ/IL-4 relationships. These data indicate that various forms of psychological stress can impact endurance exercise-based changes in certain immune biomarkers. These changes may reflect an increased susceptibility to clinical risks in some individuals.

  12. Geothermal drilling and completion technology development program. Quarterly progress report, January-March 1980

    Energy Technology Data Exchange (ETDEWEB)

    Varnado, S.G. (ed.)

    1980-04-01

    The progress, status, and results of ongoing Research and Development (R and D) within the Geothermal Drilling and Completion Technology Development Program are described. The program emphasizes the development of geothermal drilling hardware, drilling fluids, completion technology, and lost circulation control methods. Advanced drilling systems are also under development. The goals of the program are to develop the technology required to reduce well costs by 25% by 1983 and by 50% by 1987.

  13. DOWNHOLE POWER GENERATION AND WIRELESS COMMUNICATIONS FOR INTELLIGENT COMPLETIONS APPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Paul Tubel

    2003-10-14

    The fourth quarter of the project was dedicated to the manufacturing of the mechanical system for wireless communications and the power generation module and inspection pre assembly of the mechanical components. Another emphasis for the quarter was the development of filter control and signal detection software. The tasks accomplished during this report period were: (1) Dimensional issues were resolved and revised drawings for manufacturing of the wireless communications gauge and power generator were completed and sent to a machine shop for manufacturing. (2) Finalized the requirements and fittings and connections for testing the tool in the Halliburton flow loop. (3) The new acoustic generator was manufactured successfully and it was delivered during this quarter. The assembly will be outsourced for plastic coating in preparation for hostile environment use. (4) The acoustic two-way communications development continued to progress. The real time firmware for the surface system was developed and the processor was able to detect and process the data frame transmitted from downhole. The analog section of the tool was also developed and it is being tested for filtering capabilities and signal detection and amplification. (5) The new transformer to drive the acoustic generator assembly was manufactured and was successfully tested. Spring mandrel design showed increased acoustic output on the pipe and was implemented. (6) PCBA board carrier with board set was tested for function and fit and is 100% complete. (7) Filter control software is complete and software to allow modification of communication parameters dynamically is 50% complete. (8) All mechanical parts to assemble the wireless gauge and power generator have been received and verified to be within specification. (9) Acoustic generator has been assembled in the tool mandrel and tested successfully. (10) The circuit required to harvest the power generated downhole has been designed and the power generator

  14. Site Rehabilitation Completion Report with No Further Action Proposal for the Northeast Site

    Energy Technology Data Exchange (ETDEWEB)

    Daniel, Joe [Stoller Newport News Technology, Inc., Grand Junction, CO (United States); Tabor, Charles [Stoller Newport News Technology, Inc., Grand Junction, CO (United States); Survochak, Scott [U.S. Department of Energy, Office of Legacy Management, Grand Junction, CO (United States)

    2013-05-01

    The purpose of this Site Rehabilitation Completion Report is to present the post-active-remediation monitoring results for the Northeast Site and to propose No Further Action with Controls. This document includes information required by Chapter 62-780.750(4)(d), 62-780.750(6), and 62-780.600(8)(a)27 Florida Administrative Code (F.A.C.). The Closure Monitoring Plan for the Northeast Site and 4.5 Acre Site (DOE 2009a) describes the approach for post-active-remediation monitoring. The Young - Rainey Science, Technology, and Research Center (STAR Center) is a former U.S. Department of Energy (DOE) facility constructed in the mid-1950s. The 99-acre STAR Center is located in Largo, Florida. The Northeast Site is located in the northeast corner of the STAR Center. The Northeast Site meets all the requirements for an RMO II closure—No Further Action with Controls. DOE is nearing completion of a restrictive covenant for the Northeast Site. DOE has completed post-active-remediation monitoring at the Northeast Site as of September 2012. No additional monitoring will be conducted.

  15. Complete decay of radionuclides: Implications for low-level waste disposal in municipal landfills

    International Nuclear Information System (INIS)

    Meck, R.A.

    1996-01-01

    The time required for the complete decay of a radioactive source can be quantified by specifying an acceptable probability and using an original derivation. The physical phenomenon of complete decay may be used as the technical basis to change regulations and permit, with public acceptance, the inexpensive disposal of short half-lived radioactive waste into municipal landfills. Current regulations require isolation of trash form the biosphere for 30 years during the post-closure control period for municipal landfills. Thirty years is sufficient time for complete decay of significant quantities of short-lived radionuclides, and there is a large decay capacity in the nation's landfills. As the major generators of low-level radioactive waste with relatively short half-lives, the academic, medical, and research communities likely would benefit most from such regulatory relief. Disposal of such waste is prohibited or costly. The waste must be specially packaged, stored, transported, and disposed in designated repositories. Regulatory relief can be initiated by citizens since the Administrative Procedures Act gives citizens the right to petition for regulatory change. 10 refs., 2 tabs

  16. Tensor Factorization for Low-Rank Tensor Completion.

    Science.gov (United States)

    Zhou, Pan; Lu, Canyi; Lin, Zhouchen; Zhang, Chao

    2018-03-01

    Recently, a tensor nuclear norm (TNN) based method was proposed to solve the tensor completion problem, which has achieved state-of-the-art performance on image and video inpainting tasks. However, it requires computing tensor singular value decomposition (t-SVD), which costs much computation and thus cannot efficiently handle tensor data, due to its natural large scale. Motivated by TNN, we propose a novel low-rank tensor factorization method for efficiently solving the 3-way tensor completion problem. Our method preserves the low-rank structure of a tensor by factorizing it into the product of two tensors of smaller sizes. In the optimization process, our method only needs to update two smaller tensors, which can be more efficiently conducted than computing t-SVD. Furthermore, we prove that the proposed alternating minimization algorithm can converge to a Karush-Kuhn-Tucker point. Experimental results on the synthetic data recovery, image and video inpainting tasks clearly demonstrate the superior performance and efficiency of our developed method over state-of-the-arts including the TNN and matricization methods.

  17. Completeness, supervenience and ontology

    International Nuclear Information System (INIS)

    Maudlin, Tim W E

    2007-01-01

    In 1935, Einstein, Podolsky and Rosen raised the issue of the completeness of the quantum description of a physical system. What they had in mind is whether or not the quantum description is informationally complete, in that all physical features of a system can be recovered from it. In a collapse theory such as the theory of Ghirardi, Rimini and Weber, the quantum wavefunction is informationally complete, and this has often been taken to suggest that according to that theory the wavefunction is all there is. If we distinguish the ontological completeness of a description from its informational completeness, we can see that the best interpretations of the GRW theory must postulate more physical ontology than just the wavefunction

  18. Completeness, supervenience and ontology

    Energy Technology Data Exchange (ETDEWEB)

    Maudlin, Tim W E [Department of Philosophy, Rutgers University, 26 Nichol Avenue, New Brunswick, NJ 08901-1411 (United States)

    2007-03-23

    In 1935, Einstein, Podolsky and Rosen raised the issue of the completeness of the quantum description of a physical system. What they had in mind is whether or not the quantum description is informationally complete, in that all physical features of a system can be recovered from it. In a collapse theory such as the theory of Ghirardi, Rimini and Weber, the quantum wavefunction is informationally complete, and this has often been taken to suggest that according to that theory the wavefunction is all there is. If we distinguish the ontological completeness of a description from its informational completeness, we can see that the best interpretations of the GRW theory must postulate more physical ontology than just the wavefunction.

  19. Is a volume of 3.6 mL better than 1.8 mL for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis?

    Science.gov (United States)

    Fowler, Sara; Reader, Al

    2013-08-01

    The purpose of this retrospective study was to determine the success of the inferior alveolar nerve (IAN) block using either 3.6 mL or 1.8 mL 2% lidocaine with 1:100,000 epinephrine in patients presenting with symptomatic irreversible pulpitis. As part of 7 previously published studies, 319 emergency patients presenting with symptomatic irreversible pulpitis received either a 1.8-mL volume or 3.6-mL volume of 2% lidocaine with 1:100,000 epinephrine in an IAN block. One hundred ninety patients received a 1.8-mL volume, and 129 received a 3.6-mL volume. Endodontic emergency treatment was completed on each subject. Success was defined as the ability to access and instrument the tooth without pain (visual analog scale score of 0) or mild pain (VAS rating ≤54 mm). Success of the 1.8-mL volume was 28%, and for the 3.6-mL volume it was 39%. There was no statistically significant difference between the 2 volumes. In conclusion, for patients presenting with irreversible pulpitis, success was not significantly different between a 3.6-mL volume and a 1.8-mL volume of 2% lidocaine with 1:100,000 epinephrine. The success rates (28%-39%) with either volume were not high enough to ensure complete pulpal anesthesia. Copyright © 2013 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  20. Evaluation of atlas based auto-segmentation for head and neck target volume delineation in adaptive/replan IMRT

    International Nuclear Information System (INIS)

    Speight, R; Lindsay, R; Harding, R; Sykes, J; Karakaya, E; Prestwich, R; Sen, M

    2014-01-01

    IMRT for head and neck patients requires clinicians to delineate clinical target volumes (CTV) on a planning-CT (>2hrs/patient). When patients require a replan-CT, CTVs must be re-delineated. This work assesses the performance of atlas-based autosegmentation (ABAS), which uses deformable image registration between planning and replan-CTs to auto-segment CTVs on the replan-CT, based on the planning contours. Fifteen patients with planning-CT and replan-CTs were selected. One clinician delineated CTVs on the planning-CTs and up to three clinicians delineated CTVs on the replan-CTs. Replan-CT volumes were auto-segmented using ABAS using the manual CTVs from the planning-CT as an atlas. ABAS CTVs were edited manually to make them clinically acceptable. Clinicians were timed to estimate savings using ABAS. CTVs were compared using dice similarity coefficient (DSC) and mean distance to agreement (MDA). Mean inter-observer variability (DSC>0.79 and MDA<2.1mm) was found to be greater than intra-observer variability (DSC>0.91 and MDA<1.5mm). Comparing ABAS to manual CTVs gave DSC=0.86 and MDA=2.07mm. Once edited, ABAS volumes agreed more closely with the manual CTVs (DSC=0.87 and MDA=1.87mm). The mean clinician time required to produce CTVs reduced from 169min to 57min when using ABAS. ABAS segments volumes with accuracy close to inter-observer variability however the volumes require some editing before clinical use. Using ABAS reduces contouring time by a factor of three.

  1. 40 CFR 80.596 - How is a refinery motor vehicle diesel fuel volume baseline calculated?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false How is a refinery motor vehicle diesel... Requirements § 80.596 How is a refinery motor vehicle diesel fuel volume baseline calculated? (a) For purposes of this subpart, a refinery's motor vehicle diesel fuel volume baseline is calculated using the...

  2. Blood volume studies

    International Nuclear Information System (INIS)

    Lewis, S.M.; Yin, J.A.L.

    1986-01-01

    The use of dilution analysis with such radioisotopes as 51 Cr, 32 P, sup(99m)Tc and sup(113m)In for measuring red cell volume is reviewed briefly. The use of 125 I and 131 I for plasma volume studies is also considered and the subsequent determination of total blood volume discussed, together with the role of the splenic red cell volume. Substantial bibliography. (UK)

  3. Ambient temperature and volume of perihematomal edema in acute intracerebral haemorrhage: the INTERACT1 study.

    Science.gov (United States)

    Zheng, Danni; Arima, Hisatomi; Heeley, Emma; Karpin, Anne; Yang, Jie; Chalmers, John; Anderson, Craig S

    2015-01-01

    As no human data exist, we aimed to determine the relation between ambient temperature and volume of perihematomal 'cerebral' edema in acute spontaneous intracerebral haemorrhage (ICH) among Chinese participants of the pilot phase, Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT1). INTERACT1 was a multicenter, open, blind outcome assessed, randomized controlled trial of intensive (systolic target ambient temperature (mean, minimum, maximum, and range) on the day of each participant's ICH obtained from China Meteorological Data Sharing Service System were linked to other data including edema volumes. Multivariable regression analyses were performed to evaluate association between ambient temperature and edema volumes. A generalized linear regression model with a generalized estimating equations approach (GEE) was used to assess any association of ambient temperature and change in edema volume over 72 h. A total of 250 of all 384 Chinese participants had complete data that showed positive associations between ambient temperature (mean and minimum temperatures) and edema volumes at each time point over 72 h after hospital admission (all P ambient temperature and perihematomal edema volume in acute spontaneous ICH. © 2014 World Stroke Organization.

  4. Increased mean platelet volume in type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Ezgi Coşkun Yenigün

    2014-03-01

    Full Text Available Objective: Platelet functions have important roles in the development of vascular complications in diabetic patients. Platelets with increased volume have increased activity compared to smaller ones; therefore, mean platelet volume (MPV is used as a marker for platelet activity. In the present study, we evaluated MPV in patients with type II diabetes mellitus (DM and its associations with diabetic microvascular and macrovascular complications. Methods: Consecutive type II diabetic patients were screened from outpatient clinic of Internal Medicine Department of Diskapı Yıldırım Beyazıt Education and Researsch Hospital, Ankara, Turkey. A total of 48 patients with type II DM and 30 age and gender matched healthy subjects constituted the study population. For all subjects a complete blood count including MPV, fasting blood glucose level and lipid parameters were studied. In diabetic patients, duration of diabetes and HbA1C level, presence of microvascular and macrovascular complications were noted additively. Mean platelet volume was compared between diabetic patients and healthy counterparents. Then, among diabetic patients, MPV was compared between the ones with and without microvascular and macrovascular complications. Results: Mean platelet volume was found significantly higher in diabetic patients compared to non-diabetic healthy subjects. Diabetic patients with at least one of the microvascular complications had significantly higher MPV than those without microvascular damage.Higher MPV levels have also been shown in diabetics with macrovascular complications compared to the ones without macrovascular disease. Conclusion: Mean platelet volume was found to be higher in type II diabetics and those having any of microvascular or macrovascular diabetic complications.

  5. Measurement of orbital volume by computed tomography. Especially on the growth of orbit

    Energy Technology Data Exchange (ETDEWEB)

    Furuta, Minoru [Fukushima Medical Coll. (Japan)

    2000-10-01

    Using reconstructed X-ray computed tomography (CT) images of serial coronal sections, we measured the orbital volume and studied its changes with age. The subjects consisted of 109 patients (74 males, 35 females) who had undergone X-ray CT. After the reproducibility of orbital volume measurements and laterality in individuals were confirmed, the relation between the orbital volume and the age, sex, weight, and interlateral orbital rim distance were examined. The difference between two measurements in the same patients was 0.4% for measured volume, which showed the reproducibility of this measurement to be good. The laterality in individuals was 0.06 cm{sup 3}: this difference was very small and not significant. The orbital volume showed no unbalance between the right and left at any stage of growth. Both the height and the interlateral orbital rim distance had a strong correlation with the orbital volume. Referring to the relation between age and orbital volume, a strong correlation with an almost identical approximate equation was obtained for both sexes under 12 years of age. Presumably, the rapid growth of the orbit comes to an end by 15 years of age in males and 11 years in females. This means that more than 95% growth of adults has already been completed in the first half of the teens. The mean orbital volume in adult Japanese is 23.6{+-}2.0 (mean{+-}standard deviation) cm{sup 3} in males and 20.9{+-}1.3 cm{sup 3} in females. (author)

  6. Measurement of orbital volume by computed tomography. Especially on the growth of orbit

    International Nuclear Information System (INIS)

    Furuta, Minoru

    2000-01-01

    Using reconstructed X-ray computed tomography (CT) images of serial coronal sections, we measured the orbital volume and studied its changes with age. The subjects consisted of 109 patients (74 males, 35 females) who had undergone X-ray CT. After the reproducibility of orbital volume measurements and laterality in individuals were confirmed, the relation between the orbital volume and the age, sex, weight, and interlateral orbital rim distance were examined. The difference between two measurements in the same patients was 0.4% for measured volume, which showed the reproducibility of this measurement to be good. The laterality in individuals was 0.06 cm 3 : this difference was very small and not significant. The orbital volume showed no unbalance between the right and left at any stage of growth. Both the height and the interlateral orbital rim distance had a strong correlation with the orbital volume. Referring to the relation between age and orbital volume, a strong correlation with an almost identical approximate equation was obtained for both sexes under 12 years of age. Presumably, the rapid growth of the orbit comes to an end by 15 years of age in males and 11 years in females. This means that more than 95% growth of adults has already been completed in the first half of the teens. The mean orbital volume in adult Japanese is 23.6±2.0 (mean±standard deviation) cm 3 in males and 20.9±1.3 cm 3 in females. (author)

  7. 75 FR 35901 - On-Site Completion of Construction of Manufactured Homes

    Science.gov (United States)

    2010-06-23

    ... consistent with the current 5-year requirement for DAPIA retention of approved designs and design changes... these documents at the job site; (h) Providing a copy of the final site inspection report and... reasonably be completed in the factory (e.g., fireplaces at marriage lines and designs that involve such...

  8. Sample volume and alignment analysis for an optical particle counter sizer, and other applications

    International Nuclear Information System (INIS)

    Holve, D.J.; Davis, G.W.

    1985-01-01

    Optical methods for particle size distribution measurements in practical high temperature environments are approaching feasibility and offer significant advantages over conventional sampling methods. A key requirement of single particle counting techniques is the need to know features of the sample volume intensity distribution which in general are a function of the particle scattering properties and optical system geometry. In addition, the sample volume intensity distribution is sensitive to system alignment and thus calculations of alignment sensitivity are required for assessment of practical alignment tolerances. To this end, an analysis of sample volume characteristics for single particle counters in general has been developed. Results from the theory are compared with experimental measurements and shown to be in good agreement. A parametric sensitivity analysis is performed and a criterion for allowable optical misalignment is derived for conditions where beam steering caused by fluctuating refractive-index gradients is significant

  9. Functional requirements for onboard management of space shuttle consumables, volume 1

    Science.gov (United States)

    Graf, P. J.; Herwig, H. A.; Neel, L. W.

    1973-01-01

    A study was conducted to determine the functional requirements for onboard management of space shuttle consumables. A generalized consumable management concept was developed for application to advanced spacecraft. The subsystems and related consumables selected for inclusion in the consumables management system are: (1) propulsion, (2) power generation, and (3) environmental and life support.

  10. Inertial Fusion Energy reactor design studies: Prometheus-L, Prometheus-H. Volume 2, Final report

    Energy Technology Data Exchange (ETDEWEB)

    Waganer, L.M.; Driemeyer, D.E.; Lee, V.D.

    1992-03-01

    This report contains a review of design studies for Inertial Confinement reactor. This second of three volumes discussions is some detail the following: Objectives, requirements, and assumptions; rationale for design option selection; key technical issues and R&D requirements; and conceptual design selection and description.

  11. Relations between brain volumes, neuropsychological assessment and parental questionnaire in prematurely born children.

    Science.gov (United States)

    Lind, Annika; Haataja, Leena; Rautava, Liisi; Väliaho, Anniina; Lehtonen, Liisa; Lapinleimu, Helena; Parkkola, Riitta; Korkman, Marit

    2010-05-01

    The objective of this study is to assess the relationship between brain volumes at term equivalent age and neuropsychological functions at 5 years of age in very low birth weight (VLBW) children, and to compare the results from a neuropsychological assessment and a parental questionnaire at 5 years of age. The study group included a regional cohort of 97 VLBW children and a control group of 161 children born at term. At term equivalent age, brain magnetic resonance imaging (MRI) was performed on the VLBW children, and analysed for total and regional brain volumes. At 5 years of age, a psychologist assessed the neuropsychological performance with NEPSY II, and parents completed the Five to fifteen (FTF) questionnaire on development and behaviour. The results of the control group were used to give the age-specific reference values. No significant associations were found between the brain volumes and the NEPSY II domains. As for the FTF, significant associations were found between a smaller total brain tissue volume and poorer executive functions, between a smaller cerebellar volume and both poorer executive functions and motor skills, and, surprisingly, between a larger volume of brainstem and poorer language functions. Even after adjustment for total brain tissue volume, the two associations between the cerebellar volume and the FTF domains remained borderline significant (P = 0.05). The NEPSY II domains Executive Functioning, Language and Motor Skills were significantly associated with the corresponding FTF domains. In conclusion, altered brain volumes at term equivalent age appear to affect development still at 5 years of age. The FTF seems to be a good instrument when used in combination with other neuropsychological assessment.

  12. Department of Defense Financial Management Regulation. Volume 13. Nonappropriated Funds Policy and Procedures

    National Research Council Canada - National Science Library

    1994-01-01

    .... In addition, it directs statutory and regulatory financial reporting requirements. This Volume prescribes standard accounting principles and practices for all DoD nonappropriated fund instrumentalities (NAFIs...

  13. A Lean Six Sigma quality improvement project to increase discharge paperwork completeness for admission to a comprehensive integrated inpatient rehabilitation program.

    Science.gov (United States)

    Neufeld, Nathan J; Hoyer, Erik H; Cabahug, Philippines; González-Fernández, Marlís; Mehta, Megha; Walker, N Colbey; Powers, Richard L; Mayer, R Samuel

    2013-01-01

    Lean Six Sigma (LSS) process analysis can be used to increase completeness of discharge summary reports used as a critical communication tool when a patient transitions between levels of care. The authors used the LSS methodology as an intervention to improve systems process. Over the course of the project, 8 required elements were analyzed in the discharge paperwork. The authors analyzed the discharge paperwork of patients (42 patients preintervention and 143 patients postintervention) of a comprehensive integrated inpatient rehabilitation program (CIIRP). Prior to this LSS project, 61.8% of required discharge elements were present. The intervention improved the completeness to 94.2% of the required elements. The percentage of charts that were 100% complete increased from 11.9% to 67.8%. LSS is a well-established process improvement methodology that can be used to make significant improvements in complex health care workflow issues. Specifically, the completeness of discharge documentation required for transition of care to CIIRP can be improved.

  14. The estimation of bone cyst volume using the Cavalieri principle on computed tomography images.

    Science.gov (United States)

    Say, Ferhat; Gölpınar, Murat; Kılınç, Cem Yalın; Şahin, Bünyamin

    2018-01-01

    To evaluate the volume of bone cyst using the planimetry method of the Cavalieri principle. A retrospective analysis was carried out on data from 25 computed tomography (CT) images of patients with bone cyst. The volume of the cysts was calculated by two independent observers using the planimetry method. The procedures were repeated 1 month later by each observer. The overall mean volume of the bone cyst was 29.25 ± 25.86 cm 3 . The mean bone cyst volumes calculated by the first observer for the first and second sessions were 29.18 ± 26.14 and 29.27 ± 26.19 cm 3 , respectively. The mean bone cyst volumes calculated by the second observer for the first and second sessions were 29.32 ± 26.36 and 29.23 ± 26.36 cm 3 , respectively. Statistical analysis showed no difference and high agreement between the first and second measurements of both observers. The Bland-Altman plots showed strong intraobserver and interobserver concordance in the measurement of the bone cyst volume. The mean total time necessary to obtain the cyst volume by the two observers was 5.27 ± 2.30 min. The bone cyst of the patients can be objectively evaluated using the planimetry method of the Cavalieri principle on CT. This method showed high interobserver and intraobserver agreement. This volume measurement can be used to evaluate cyst remodeling, including complete healing and cyst recurrence.

  15. Robust volume calculations for Constructive Solid Geometry (CSG) components in Monte Carlo transport calculations

    Energy Technology Data Exchange (ETDEWEB)

    Millman, D. L. [Dept. of Computer Science, Univ. of North Carolina at Chapel Hill (United States); Griesheimer, D. P.; Nease, B. R. [Bechtel Marine Propulsion Corporation, Bertis Atomic Power Laboratory (United States); Snoeyink, J. [Dept. of Computer Science, Univ. of North Carolina at Chapel Hill (United States)

    2012-07-01

    In this paper we consider a new generalized algorithm for the efficient calculation of component object volumes given their equivalent constructive solid geometry (CSG) definition. The new method relies on domain decomposition to recursively subdivide the original component into smaller pieces with volumes that can be computed analytically or stochastically, if needed. Unlike simpler brute-force approaches, the proposed decomposition scheme is guaranteed to be robust and accurate to within a user-defined tolerance. The new algorithm is also fully general and can handle any valid CSG component definition, without the need for additional input from the user. The new technique has been specifically optimized to calculate volumes of component definitions commonly found in models used for Monte Carlo particle transport simulations for criticality safety and reactor analysis applications. However, the algorithm can be easily extended to any application which uses CSG representations for component objects. The paper provides a complete description of the novel volume calculation algorithm, along with a discussion of the conjectured error bounds on volumes calculated within the method. In addition, numerical results comparing the new algorithm with a standard stochastic volume calculation algorithm are presented for a series of problems spanning a range of representative component sizes and complexities. (authors)

  16. Robust volume calculations for Constructive Solid Geometry (CSG) components in Monte Carlo transport calculations

    International Nuclear Information System (INIS)

    Millman, D. L.; Griesheimer, D. P.; Nease, B. R.; Snoeyink, J.

    2012-01-01

    In this paper we consider a new generalized algorithm for the efficient calculation of component object volumes given their equivalent constructive solid geometry (CSG) definition. The new method relies on domain decomposition to recursively subdivide the original component into smaller pieces with volumes that can be computed analytically or stochastically, if needed. Unlike simpler brute-force approaches, the proposed decomposition scheme is guaranteed to be robust and accurate to within a user-defined tolerance. The new algorithm is also fully general and can handle any valid CSG component definition, without the need for additional input from the user. The new technique has been specifically optimized to calculate volumes of component definitions commonly found in models used for Monte Carlo particle transport simulations for criticality safety and reactor analysis applications. However, the algorithm can be easily extended to any application which uses CSG representations for component objects. The paper provides a complete description of the novel volume calculation algorithm, along with a discussion of the conjectured error bounds on volumes calculated within the method. In addition, numerical results comparing the new algorithm with a standard stochastic volume calculation algorithm are presented for a series of problems spanning a range of representative component sizes and complexities. (authors)

  17. Phase equilibria and excess molar volumes of tetrahydrofuran (1) + deuterium oxide (2)

    International Nuclear Information System (INIS)

    Lejcek, P.; Matous, J.; Novak, J.P.; Pick, J.

    1975-01-01

    Vapour + liquid equilibrium at 313.15 and 333.15K, liquid + liquid equilibrium throughout the whole region of limited miscibility, and excess molar volumes at 298.15K have been studied for tetrahydrofuran + deuterium oxide. The mixtures show large positive deviations from Raoult's law and a closed loop of limited miscibility. The modified Redlich-Kister equation has been used for the correlation of the vapour + liquid equilibrium. The computation has been carried out according to a recently proposed procedure which makes it possible to obtain such constants of the correlation relation which are not inconsistent with physical reality, i.e. with the complete miscibility (partial delta 2 G/deltax 1 2 >0) under experimental conditions. Thermodynamic consistency was checked by the classical Redlich-Kister test and the one proposed by Ulrichson and Stevenson. Excess molar volumes are negative at all compositions with a point of inflexion in the water-rich region which indicates the extremes in partial molar volumes. (author)

  18. The Aftermath of Remedial Math: Investigating the Low Rate of Certificate Completion among Remedial Math Students

    Science.gov (United States)

    Bahr, Peter Riley

    2013-01-01

    Nationally, a majority of community college students require remedial assistance with mathematics, but comparatively few students who begin the remedial math sequence ultimately complete it and achieve college-level math competency. The academic outcomes of students who begin the sequence but do not complete it are disproportionately unfavorable:…

  19. Ground-water monitoring compliance projects for Hanford site facilities: Progress report for the period January 1 to March 31, 1988: Volume 7, Appendix B (contd)

    Energy Technology Data Exchange (ETDEWEB)

    1988-05-01

    This appendix is one of nine volumes, and presents data describing wwlls completed at the Hanford Site during the fourth quarter of calendar year 1987 (October through December). The data in this volume of Appendix B cover the following wells: 299-W10-14; 299-W15-15; 299-W15-16; 299-W15-17; 299-W15-18. The data are presented in the following order: Well Completion Report/Title III Inspection List, Inspection Plan, As-Built Diagram, Logging Charts, and Drill Logs.

  20. A prototype of volume-controlled tidal liquid ventilator using independent piston pumps.

    Science.gov (United States)

    Robert, Raymond; Micheau, Philippe; Cyr, Stéphane; Lesur, Olivier; Praud, Jean-Paul; Walti, Hervé

    2006-01-01

    Liquid ventilation using perfluorochemicals (PFC) offers clear theoretical advantages over gas ventilation, such as decreased lung damage, recruitment of collapsed lung regions, and lavage of inflammatory debris. We present a total liquid ventilator designed to ventilate patients with completely filled lungs with a tidal volume of PFC liquid. The two independent piston pumps are volume controlled and pressure limited. Measurable pumping errors are corrected by a programmed supervisor module, which modifies the inserted or withdrawn volume. Pump independence also allows easy functional residual capacity modifications during ventilation. The bubble gas exchanger is divided into two sections such that the PFC exiting the lungs is not in contact with the PFC entering the lungs. The heating system is incorporated into the metallic base of the gas exchanger, and a heat-sink-type condenser is placed on top of the exchanger to retrieve PFC vapors. The prototype was tested on 5 healthy term newborn lambs (<5 days old). The results demonstrate the efficiency and safety of the prototype in maintaining adequate gas exchange, normal acido-basis equilibrium, and cardiovascular stability during a short, 2-hour total liquid ventilator. Airway pressure, lung volume, and ventilation scheme were maintained in the targeted range.