Two-echelon transportation optimisation: a meta-narrative analysis

Directory of Open Access Journals (Sweden)

Jesus Gonzalez-Feliu

2011-02-01

Full Text Available Freight transportation constitutes one of the main activities that influences economy and society, as it assures a vital link between suppliers and customers and it represents a major source of employment. Multi-echelon distribution is one of the most common strategies adopted by the transportation companies in an aim of cost reduction. Although vehicle routing problems are very common in operational research, they are essentially related to single-echelon cases. This paper presents the main concepts of multi-echelon distribution with cross-docks and a unified notation for two-chelon transportation cost optimization. A systematic review is also presented, in order to list the main issues and methods that can be helpful for scientists and transportation practitioners.

Transportation: the vital tendons of the nuclear industry

International Nuclear Information System (INIS)

Jefferson, R.M.

1979-01-01

Of the 100 million packages of hazardous materials shipped each year, about 2 million contain radioactive materials; of these, only about 350,000 pertain to the fuel cycle and to radioactive wastes. A brief description is given of the philosophy responsible for the safe transportation of radioactive materials for the past 30 years. The range of problems facing the industry in the transportation of radioactive materials is discussed. DOE established a Transportation Technology Center at Sandia Laboratories in order to meet these problems

The Role of Glucose Transporters in Brain Disease: Diabetes and Alzheimer’s Disease

Science.gov (United States)

Shah, Kaushik; DeSilva, Shanal; Abbruscato, Thomas

2012-01-01

The occurrence of altered brain glucose metabolism has long been suggested in both diabetes and Alzheimer’s diseases. However, the preceding mechanism to altered glucose metabolism has not been well understood. Glucose enters the brain via glucose transporters primarily present at the blood-brain barrier. Any changes in glucose transporter function and expression dramatically affects brain glucose homeostasis and function. In the brains of both diabetic and Alzheimer’s disease patients, changes in glucose transporter function and expression have been observed, but a possible link between the altered glucose transporter function and disease progress is missing. Future recognition of the role of new glucose transporter isoforms in the brain may provide a better understanding of brain glucose metabolism in normal and disease states. Elucidation of clinical pathological mechanisms related to glucose transport and metabolism may provide common links to the etiology of these two diseases. Considering these facts, in this review we provide a current understanding of the vital roles of a variety of glucose transporters in the normal, diabetic and Alzheimer’s disease brain. PMID:23202918

CDC Vital Signs-Zika and Pregnancy: What You Should Know

Centers for Disease Control (CDC) Podcasts

This podcast is based on the April 2016 CDC Vital Signs report. A pregnant woman who is infected with Zika virus can pass it to her fetus which is linked to microcephaly, a serious birth defect. This podcast discusses how to protect yourself from Zika virus.

The Curriculum Material Center's Vital Link to Play and Learning: What's the Connection?

Science.gov (United States)

Madray, Amrita; Catalano, Amy

2010-01-01

Many educational theorists who study child development concur that the importance of play related materials in schools, homes and libraries is vital to the concept of play and learning. As academic librarians responsible for information literacy, and as the education liaison for the management and collection development of the instructional…

Indigenous Māori perspectives on urban transport patterns linked to health and wellbeing.

Science.gov (United States)

Raerino Ngāti Awa Te Arawa, K; Macmillan, Alex K; Jones Ngāti Kahungunu, Rhys G

2013-09-01

There is a growing body of research linking urban transport systems to inequities in health. However, there is a lack of research providing evidence of the effect of transport systems on indigenous family wellbeing. We examined the connections between urban transport and the health and wellbeing of Māori, the indigenous people of New Zealand. We provide an indigenous exploration of current urban transport systems, with a particular focus on the impacts of car dependence and the need for culturally relevant travel. We interviewed nineteen Māori participants utilising qualitative research techniques underpinned by an indigenous research methodology (Kaupapa Māori). The data highlighted the importance of accessing cultural activities and sites relevant to 'being Māori', and issues with affordability and safety of public transport. Understanding the relationship between indigenous wellbeing and transport systems that goes further than limited discourses of inequity is essential to improving transport for indigenous wellbeing. Providing an indigenous voice in transport decision-making will make it more likely that indigenous health and wellbeing is prioritised in transport planning. Copyright © 2013. Published by Elsevier Ltd.

Vital Stats (Vital Statistics Tables and files- Births, Infant Deaths, Fetal Deaths)

Data.gov (United States)

U.S. Department of Health & Human Services — VitalStats: A collection of vital statistics products including tables, data files, and reports that allow users to access and examine vital statistics and...

Link between defoliation and light treatments on root vitality of five understory shrubs with different resistance to insect herbivory.

Science.gov (United States)

Karolewski, Piotr; Zadworny, Marcin; Mucha, Joanna; Napierała-Filipiak, Anna; Oleksyn, Jacek

2010-08-01

Understory shrubs are frequently attacked by insect herbivores. However, very little is known regarding possible interactions between light condition, defoliation (D) and fine root vitality (% live roots) and metabolic activity, and whether different plant strategies (compensation, trade-off and equilibrium) to defoliation depend on individual species light requirements. To explore the response of roots to such conditions, an experiment was established in which we experimentally removed 50% of leaves in 1-year-old seedlings of Sambucus nigra, Cornus sanguinea, Prunus serotina, Frangula alnus and Corylus avellana grown in 15% and full sunlight. On average, defoliation leads to a 15% reduction in fine root (vitality (% live roots). However, a statistically significant reduction in root vitality after defoliation was detected only in those species that are less herbivorized in nature (48% in S. nigra and 5% in C. sanguinea). On average, shade conditions (L) resulted in 18% decline in root vitality, and the effects of defoliation were also 22% higher than for plants grown in full light. Root vitality in both treatments (D and L) was significantly correlated with their dry mass, concentration of total phenol (TPh) and carbon to nitrogen ratio, and negatively correlated with nitrogen, soluble carbohydrates, starch and total non-structural carbohydrates (TNC). To a large extent, root vitality and chemistry varied by species. Higher root vitality was related to higher concentrations of phenolics, more than to N and TNC concentrations. Concentrations of phenolics also differed significantly between defoliated plants and controls. However, in defoliated plants, an increase in TPh was observed only in two species, which belong to two different groups in light requirements and susceptibility to insect grazing (C. sanguinea and P. serotina). This study indicated that higher vitality of roots occurred in species that are characterized by higher insect defoliation under natural

Identifying the Critical Links in Road Transportation Networks: Centrality-based approach utilizing structural properties

Energy Technology Data Exchange (ETDEWEB)

Chinthavali, Supriya [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2016-04-01

Surface transportation road networks share structural properties similar to other complex networks (e.g., social networks, information networks, biological networks, and so on). This research investigates the structural properties of road networks for any possible correlation with the traffic characteristics such as link flows those determined independently. Additionally, we define a criticality index for the links of the road network that identifies the relative importance in the network. We tested our hypotheses with two sample road networks. Results show that, correlation exists between the link flows and centrality measures of a link of the road (dual graph approach is followed) and the criticality index is found to be effective for one test network to identify the vulnerable nodes.

CDC Vital Signs–Cancer and Tobacco Use

Centers for Disease Control (CDC) Podcasts

2016-11-10

This podcast is based on the November 2016 CDC Vital Signs report. There is a long list of cancers linked to tobacco use, the leading preventable cause of cancer and cancer deaths. Learn more here.  Created: 11/10/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 11/10/2016.

On the link between the q-profile and internal transport barriers

Energy Technology Data Exchange (ETDEWEB)

Baranov, Yu F [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Garbet, X [Association Euratom-CEA, CE de Cadarache, F-13108, St Paul lez Durance (France); Hawkes, N C [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Alper, B [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Barnsley, R [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Challis, C D [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Giroud, C [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Joffrin, E [Association Euratom-CEA, CE de Cadarache, F-13108, St Paul lez Durance (France); Mantsinen, M [Helsinki University of Technology, Association Euratom-Tekes (Finland); Orsitto, F [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, Frascati (Italy); Parail, V [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Sharapov, S E [EURATOM/UKAEA Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom)

2004-08-01

Numerous experiments were performed on JET to clarify the link between rational q, magnetic shear and internal transport barriers (ITBs) by varying the q-profile from a monotonic one to one with a central reversed shear (Challis et al 2002 Plasma Phys. Control. Fusion 44 1031). The q-profile was found to be crucial in two cases: for ITB formation in the presence of a strong negative magnetic shear and for ITBs in the vicinity of low order rational q surfaces with a small magnetic shear. The ITBs of these two types have been modelled and analysed in this work using transport codes (TRANSP, JETTO, TRB). Transport coefficients were calculated using several widely used theories of micro-turbulence and compared with data deduced from the experiment to verify the applicability of the theories. Different underlying physical mechanisms were found to be responsible for ITB formation in a negative magnetic shear and in the vicinity of a rational minimum q.

TULIP: A Link-Level Protocol for Improving TCP over Wireless Links

National Research Council Canada - National Science Library

Parsa, Christina; Garcia-Luna-Aceves, J. J

1999-01-01

We present the transport unaware link improvement protocol (TULIP), which dramatically improves the performance of TCP over lossy wireless links, without competing with or modifying the transport- or network-layer protocols...

Filling the Gap : Relationship Between the Serotonin-Transporter-Linked Polymorphic Region and Amygdala Activation

NARCIS (Netherlands)

Bastiaansen, Jojanneke A.; Servaas, Michelle N.; Marsman, Jan-Bernard; Ormel, Johan; Nolte, Ilja M.; Riese, Harriette; Aleman, Andre

2014-01-01

The alleged association between the serotonin-transporter-linked polymorphic region (5-HTTLPR) and amygdala activation forms a cornerstone of the common view that carrying the short allele of this polymorphism is a potential risk factor for affective disorders. The authors of a recent meta-analysis

Filling the Gap : Relationship Between the Serotonin-Transporter-Linked Polymorphic Region and Amygdala Activation

NARCIS (Netherlands)

Bastiaansen, Jojanneke A.; Servaas, Michelle N.; Marsman, Jan-Bernard; Ormel, Johan; Nolte, Ilja M.; Riese, Harriette; Aleman, Andre

The alleged association between the serotonin-transporter-linked polymorphic region (5-HTTLPR) and amygdala activation forms a cornerstone of the common view that carrying the short allele of this polymorphism is a potential risk factor for affective disorders. The authors of a recent meta-analysis

Tunable electronic transport properties of silicon-fullerene-linked nanowires: Semiconductor, conducting wire, and tunnel diode

OpenAIRE

Nishio, Kengo; Ozaki, Taisuke; Morishita, Tetsuya; Mikami, Masuhiro

2010-01-01

We explore the possibility of controllable tuning of the electronic transport properties of silicon-fullerene-linked nanowires by encapsulating guest atoms into their cages. Our first-principles calculations demonstrate that the guest-free nanowires are semiconductors, and do not conduct electricity. The iodine or sodium doping improves the transport properties, and makes the nanowires metallic. In the junctions of I-doped and Na-doped NWs, the current travels through the boundary by quantum ...

Making the Link between Libraries and Adult Basic Skills.

Science.gov (United States)

Clarke, Genevieve

2002-01-01

Vital Link is a British program that links national reading and literacy organizations with libraries. The focus is on how libraries can support and motivate existing learners while attracting new learners. (JOW)

Modality Environments : A Concept For Sustainability And Vitality In The Multi-Modal City

NARCIS (Netherlands)

Read, S.A.; Lopes Gil, J.A.

2017-01-01

This paper reviews an idea of vital local high-street places with their walking spaces and economies founded in interfaces between neighbourhood and city (between walking and public transport/bicycle movement infrastructures). It then extends this idea to higher scales, considering interfaces

CDC Vital Signs-Zika and Pregnancy: What You Should Know

Centers for Disease Control (CDC) Podcasts

2016-04-01

This podcast is based on the April 2016 CDC Vital Signs report. A pregnant woman who is infected with Zika virus can pass it to her fetus which is linked to microcephaly, a serious birth defect. This podcast discusses how to protect yourself from Zika virus.  Created: 4/1/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 4/1/2016.

Transport link scanner: simulating geographic transport network expansion through individual investments

Science.gov (United States)

Jacobs-Crisioni, C.; Koopmans, C. C.

2016-07-01

This paper introduces a GIS-based model that simulates the geographic expansion of transport networks by several decision-makers with varying objectives. The model progressively adds extensions to a growing network by choosing the most attractive investments from a limited choice set. Attractiveness is defined as a function of variables in which revenue and broader societal benefits may play a role and can be based on empirically underpinned parameters that may differ according to private or public interests. The choice set is selected from an exhaustive set of links and presumably contains those investment options that best meet private operator's objectives by balancing the revenues of additional fare against construction costs. The investment options consist of geographically plausible routes with potential detours. These routes are generated using a fine-meshed regularly latticed network and shortest path finding methods. Additionally, two indicators of the geographic accuracy of the simulated networks are introduced. A historical case study is presented to demonstrate the model's first results. These results show that the modelled networks reproduce relevant results of the historically built network with reasonable accuracy.

THE PERSPECTIVES OF MARITIME TRANSPORT IN EU AND ITS INTEGRATION IN THE SUPPLY CHAIN MANAGEMENT

Directory of Open Access Journals (Sweden)

Voicu-Dorobantu Roxana

2010-12-01

Full Text Available In a globalised economy transport is one of the most important factors linking the national economies and maritime transport is the main way to deliver goods in international trade. For any international company, choosing the appropriate transportation as part of the logistic solution is vital for its competitiveness. In the context of the economic crisis, CEE strategic location factors play an important role for regional companies which adapt and change their logistic services by developing new scenarios for the shipping industry in order to obtain a better position on the global market. In addition to a favourable geographical location CEE has several other important arguments, like sufficient harbours for developing container terminals to launch extensive container transport transit. The most important recent trends in logistics are shown, as well as the framework of the EU maritime transport.

Future orientation and health quality of life in primary care: vitality as a mediator.

Science.gov (United States)

Hirsch, Jameson K; Molnar, Danielle; Chang, Edward C; Sirois, Fuschia M

2015-07-01

Temporal perspective, including views about future goals, may influence motivational processes related to health. An adaptive sense of future orientation is linked to better health, but little research has examined potential underlying factors, such as vitality. In a sample of 101 primary care patients, we examined whether belief in the changeability of the future was related to mental and physical energization and, in turn, to health-related quality of life. Participants were working, uninsured primary care patients, who completed self-report measures of future orientation, vitality, and health-related quality of life. Mediation models, covarying age, sex, and race/ethnicity indicated that vitality significantly mediated the association between future orientation and the outcomes of general health, mental health, social functioning, bodily pain, and role limitations due to emotional and physical reasons. Vitality exerted an indirect-only effect on the relation between future orientation and physical functioning. Our findings suggest that adaptive beliefs about the future may promote, or allow access to, physical and mental energy and, in turn, may result in better mental and physical health functioning. Individual-level and public health interventions designed to promote future orientation and vitality may beneficially influence quality of life and well-being.

Ethnolinguistic Vitality and Intergroup Processes

Science.gov (United States)

Ehala, Martin

2010-01-01

The paper argues that ethnolinguistic vitality depends on four crucial social psychological factors: perceived strength differential, intergroup distance, utilitarianism and intergroup discordance. The influence of these factors on the vitality of subordinate and dominant groups is outlined. It is proposed that the vitality of both types of groups…

Comparison of Vital Statistics Definitions of Suicide against a Coroner Reference Standard: A Population-Based Linkage Study.

Science.gov (United States)

Gatov, Evgenia; Kurdyak, Paul; Sinyor, Mark; Holder, Laura; Schaffer, Ayal

2018-03-01

We sought to determine the utility of health administrative databases for population-based suicide surveillance, as these data are generally more accessible and more integrated with other data sources compared to coroners' records. In this retrospective validation study, we identified all coroner-confirmed suicides between 2003 and 2012 in Ontario residents aged 21 and over and linked this information to Statistics Canada's vital statistics data set. We examined the overlap between the underlying cause of death field and secondary causes of death using ICD-9 and ICD-10 codes for deliberate self-harm (i.e., suicide) and examined the sociodemographic and clinical characteristics of misclassified records. Among 10,153 linked deaths, there was a very high degree of overlap between records coded as deliberate self-harm in the vital statistics data set and coroner-confirmed suicides using both ICD-9 and ICD-10 definitions (96.88% and 96.84% sensitivity, respectively). This alignment steadily increased throughout the study period (from 95.9% to 98.8%). Other vital statistics diagnoses in primary fields included uncategorised signs and symptoms. Vital statistics records that were misclassified did not differ from valid records in terms of sociodemographic characteristics but were more likely to have had an unspecified place of injury on the death certificate ( P statistics and coroner classification of suicide deaths suggests that health administrative data can reliably be used to identify suicide deaths.

Reactor vital equipment determination techniques

International Nuclear Information System (INIS)

Bott, T.F.; Thomas, W.S.

1983-01-01

The Reactor Vital Equipment Determination Techniques program at the Los Alamos National Laboratory is discussed. The purpose of the program is to provide the Nuclear Regulatory Commission (NRC) with technical support in identifying vital areas at nuclear power plants using a fault-tree technique. A reexamination of some system modeling assumptions is being performed for the Vital Area Analysis Program. A short description of the vital area analysis and supporting research on modeling assumptions is presented. Perceptions of program modifications based on the research are outlined, and the status of high-priority research topics is discussed

The air we breathe: three vital respiratory gases and the red blood cell: oxygen, nitric oxide, and carbon dioxide.

Science.gov (United States)

Dzik, Walter H

2011-04-01

Three vital respiratory gases-oxygen (O(2)), nitric oxide (NO), and carbon dioxide (CO(2))-intersect at the level of the human red blood cell (RBC). In addition to hemoglobin (Hb)'s central role in O(2) transport, interaction of Hb with the Band 3 metabolon balances RBC energy flow. 2,3-Diphosphoglycerate enhances O(2) transport across the placenta and plays an important role in regulating RBC plasticity. NO is a key mediator of hypoxic vasodilation, but the precise role of RBC Hb remains controversial. In addition to established theories that depend on RBC uptake, delivery, and discharge of NO or its metabolites, an alternative hypothesis based on RBC permeability is suggested. NO depletion by free Hb may account for several clinical features seen during intravascular hemolysis or during deliberate infusion of Hb solutions used as RBC substitutes. CO(2) released by tissues triggers oxygen release through a series of well-coordinated reactions centered on the Band 3 metabolon. While RBC carbonic anhydrase and the Band 3 anion exchanger are central to this process, there is surprisingly little research on the kinetics of CO(2) clearance by transfusion. The three RBC gases are directly related to the three principal gases of Earth's atmosphere. Human fossil fuel consumption dumps 90 million metric tons of carbon into the atmosphere annually. Increasing CO(2) levels are linked to global warming, melting Arctic ice, rising sea levels, and climate instability. Just as individual cells depend on balance of the three vital gases, so too will their balance determine survival of life on Earth. © 2011 American Association of Blood Banks.

Liberalism in foreign trade versus liberalism in air transportation - is there a link?

Directory of Open Access Journals (Sweden)

Grancay Martin

2014-01-01

Full Text Available The aim of this paper is to determine whether there is a statistically significant link between regulation of international civil aviation and protectionism against foreign trade. We use weighted air liberalization index (WALI as a proxy for the level of regulation in a country’s foreign aviation relations; trade tariff restrictiveness index (TTRI and overall trade restrictiveness index (OTRI as proxies for the level of protectionism in a country’s foreign trade. Correlation analysis shows that there is no statistically significant link between the indicators. Hence, our research confirms the view that air transportation is a specific sector and it is subject to a different kind of policies than trade in goods. We also demonstrate that large high-income countries tend to have a more liberal approach to international civil aviation than small low-income countries.

Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment.

Science.gov (United States)

Hastrup, H; Karlin, A; Javitch, J A

2001-08-28

There is evidence both for and against Na(+)- and Cl(-)-dependent neurotransmitter transporters forming oligomers. We found that cross-linking the human dopamine transporter (DAT), which is heterologously expressed in human embryonic kidney 293 cells, either with copper phenanthroline (CuP) or the bifunctional reagent bis-(2-methanethiosulfonatoethyl)amine hydrochloride (bis-EA) increased the apparent molecular mass determined with nonreducing SDS/PAGE from approximately 85 to approximately 195 kDa. After cross-linking, but not before, coexpressed, differentially epitope-tagged DAT molecules, solubilized in Triton X-100, were coimmunoprecipitated. Thus, the 195-kDa complex was a homodimer. Cross-linking of DAT did not affect tyramine uptake. Replacement of Cys-306 with Ala prevented cross-linking. Replacement of all of the non-disulfide-bonded cysteines in the extracellular and membrane domains, except for Cys-306, did not prevent cross-linking. We conclude that the cross-link is between Cys-306 at the extracellular end of TM6 in each of the two DATs. The motif GVXXGVXXA occurs at the intracellular end of TM6 in DAT and is found in a number of other neurotransmitter transporters. This sequence was originally found at the dimerization interface in glycophorin A, and it promotes dimerization in model systems. Mutation of either glycine disrupted DAT expression and function. The intracellular end of TM6, like the extracellular end, is likely to be part of the dimerization interface.

46 CFR 169.642 - Vital systems.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Vital systems. 169.642 Section 169.642 Shipping COAST... Electrical Piping Systems § 169.642 Vital systems. For the purpose of this part, the following are considered vital systems— (a) A marine engineering system identified by the OCMI as being crucial to the survival...

Making links: on (re)engaging with transport and transport geography

NARCIS (Netherlands)

Shaw, J.; Sidaway, J.D.

2011-01-01

Recent reviews have suggested a vibrancy and diversity in transport geography. But these articles were the first progress reports on transport geography since 1988, indicating how the field has been relatively marginal to broader disciplinary debates. Meanwhile, a lively literature on mobilities has

Linking air and water transport in intact soils to macropore characteristics inferred from X-ray computed tomography

DEFF Research Database (Denmark)

Katuwal, S.; Nørgaard, Trine; Møldrup, Per

2015-01-01

Soil macropores often control fluid flow and solute transport, and quantification of macropore characteristics including their variability in space and time are essential to predict soil hydraulic and hydrogeochemical functions. In this study, measurements of air and solute transport properties...... and direct macropore visualization by X-ray CT scanning were carried out on 17 large (19-cm diam.; 20-cm length) undisturbed soil columns sampled across a field site (Silstrup, Denmark) with natural gradients in texture and density. Air permeability (ka) at in-situ water content and -20 hPa of matric......-porosity, suggesting that density is the main control of functional soil structure and gas and solute transport at the Silstrup site. Linking gas transport and chemical tracer experiments with X-ray CT based visualization and quantification of macro-porosity was found to be a powerful method to understand field scale...

Incidence of post-operative pain following single visit endodontics in vital and non-vital teeth: An in vivo study

Science.gov (United States)

Bhagwat, Sumita; Mehta, Deepil

2013-01-01

This clinical study was conducted to compare the post-operative pain following single visit endodontics in vital and non-vital teeth, with and without periapical radiolucency. A total of 60 adult patients requiring root canal therapy in anterior and premolar teeth were selected for this study. Single sitting root canal treatment was carried out and the subjects were recalled after 2 weeks and instructed to fill out a series of self-report questionnaires for responses about pain in the interim after 1 day, 2 day, 3 day, 1 week and 2 weeks. In vital teeth (Group I) 60% of the treated cases had pain, of which 36% had mild pain (non-significant) and 24% had moderate pain (significant). In non-vital teeth without periapical radiolucency (Group II) 64% of cases had pain, of which 48% had mild pain (non-significant) and 16% had moderate pain (significant). In non-vital teeth with periapical radiolucency (Group III) 32% of the cases had pain of which 24% had mild pain (non-significant) and 8% had moderate pain (significant). None of the teeth in any of the groups had severe pain. There was no statistical difference between incidence of pain in vital and non-vital teeth without periapical radiolucency. Non-vital teeth with periapical radiolucency exhibited relatively less pain as compared with non-vital teeth without periapical radiolucency, but the pain continued in a significant percent of teeth even after 2 weeks. Pain incidence dropped significantly within a period of 1 day to 2 weeks in vital teeth and non-vital teeth without periapical radiolucency. There was a tendency for less incidence of significant pain after a single visit root canal treatment in these groups. Results obtained were comparable with those obtained by several investigators. PMID:24124293

Linking the Power and Transport Sectors—Part 2: Modelling a Sector Coupling Scenario for Germany

Directory of Open Access Journals (Sweden)

Martin Robinius

2017-07-01

Full Text Available “Linking the power and transport sectors—Part 1” describes the general principle of “sector coupling” (SC, develops a working definition intended of the concept to be of utility to the international scientific community, contains a literature review that provides an overview of relevant scientific papers on this topic and conducts a rudimentary analysis of the linking of the power and transport sectors on a worldwide, EU and German level. The aim of this follow-on paper is to outline an approach to the modelling of SC. Therefore, a study of Germany as a case study was conducted. This study assumes a high share of renewable energy sources (RES contributing to the grid and significant proportion of fuel cell vehicles (FCVs in the year 2050, along with a dedicated hydrogen pipeline grid to meet hydrogen demand. To construct a model of this nature, the model environment “METIS” (models for energy transformation and integration systems we developed will be described in more detail in this paper. Within this framework, a detailed model of the power and transport sector in Germany will be presented in this paper and the rationale behind its assumptions described. Furthermore, an intensive result analysis for the power surplus, utilization of electrolysis, hydrogen pipeline and economic considerations has been conducted to show the potential outcomes of modelling SC. It is hoped that this will serve as a basis for researchers to apply this framework in future to models and analysis with an international focus.

Bone vitality in the cat's irradiated jaw

International Nuclear Information System (INIS)

Dambrain, R.; Dhem, A.; Gueulette, J.; Wambersie, A.

1988-01-01

The vitality of the mandible in cats was studied from two to 15 months after irradiation. Dose of 80 Gy in three days was delivered using three hairpin shape iridium-192 wires surrounding the mandibula. The osseous vitality was assessed from the percentages of lacunae inhabited by osteocytes (IL). The results are compared with those obtained by microradiography. At two months, a small reduction of vitality is already observed, it becomes progressively more important. At one year, vitality is recovered nearly fully in the ventral part of the mandibula, mainly at the level of the alveolar crest. Vitality remains reduced in the dorsal part. Microradiographic lesions appear more slowly; they are apparent at six months. (orig.) [de

Methods of sperm vitality assessment.

Science.gov (United States)

Moskovtsev, Sergey I; Librach, Clifford L

2013-01-01

Sperm vitality is a reflection of the proportion of live, membrane-intact spermatozoa determined by either dye exclusion or osmoregulatory capacity under hypo-osmotic conditions. In this chapter we address the two most common methods of sperm vitality assessment: eosin-nigrosin staining and the hypo-osmotic swelling test, both utilized in clinical Andrology laboratories.

Making the Vital Link.

Science.gov (United States)

Clarke, Genevieve

2003-01-01

Discusses how libraries have the potential to support and motivate adults wanting to improve their literacy skills. Reports on a British initiative to bring together libraries and basic skills providers. (Author/JOW)

Vitality: Carnal, Seraphic Bodies

Directory of Open Access Journals (Sweden)

Brian Treanor

2017-09-01

Full Text Available This paper reflects on experiences of what i call vitality. Such experiences are neither idiosyncratic (they overlap major themes in Chinese philosophy, among other disciplines nor mere romanticism (contemporary psychology lends credence to these accounts. Moreover, while some figures in continental philosophy do address the body—as perceiving, as sexed, as political—there has been almost no attention given to the active body of vitality. Drawing from the work of Michel Serres, this paper will uncover some of the significant features of such bodily experiences.

New ways enhancing the vital activity of plants in order to increase crop yields and to suppress radionuclide accumulation

International Nuclear Information System (INIS)

Goncharova, N. V; Zebrakova, I. V.; Matsko, V. P.; Kislushko, P. M.

1994-01-01

After Chernobyl nuclear accident it has become very important to seek new ways of enhancing the vital activity of plants in order to increase crop yields and to suppress radionuclide accumulation. It is found that by optimizing the vital activity processes in plants, is possible to reduce radionuclide uptake. A great number of biologically active compounds have been tested, which increased the disease resistance of plants and simultaneously activated the physiological and biochemical processes that control the transport of micro- and macroelements (radionuclide included) and their 'soil-root-stem-leaf' redistribution. (author)

Sharing Vital Signs between mobile phone applications.

Science.gov (United States)

Karlen, Walter; Dumont, Guy A; Scheffer, Cornie

2014-01-01

We propose a communication library, ShareVitalSigns, for the standardized exchange of vital sign information between health applications running on mobile platforms. The library allows an application to request one or multiple vital signs from independent measurement applications on the Android OS. Compatible measurement applications are automatically detected and can be launched from within the requesting application, simplifying the work flow for the user and reducing typing errors. Data is shared between applications using intents, a passive data structure available on Android OS. The library is accompanied by a test application which serves as a demonstrator. The secure exchange of vital sign information using a standardized library like ShareVitalSigns will facilitate the integration of measurement applications into diagnostic and other high level health monitoring applications and reduce errors due to manual entry of information.

A tourism and cultural regional case study of the link between transportation and tourism: South of France

Directory of Open Access Journals (Sweden)

Jocelyne Napoli

2017-05-01

Full Text Available The article discusses the evolving role of transportation, and more especially air transport enabling tourism access to regions in the South of France. Historically, British citizens visited France by train, coach or car as the cost of air travel was restrictive and routes were only established in larger cities. ith the advent of the Channel Tunnel and Low Cost Carriers (LCCs in Europe, British tourism has increased within numerous destinations in France. These new means of transportation have filled the gap by providing easy access to smaller towns and allowing British tourists the French quality of life in the countryside. There is a shift in visitation numbers from the north of France to the south due to the wider range of travel choices. The South of France is becoming more attractive to British tourism because of the comparatively inexpensive cost of housing, the historical links between the two countries, and the cultural heritage of tradition. Other attractions include landscapes, the Mediterranean climate, restored medieval castles and villages, and the abundance of traditional French cuisine with regional wines. Due to the availability of LCCs some British tourists have chosen to settle and enjoy the historical links that are famous between the two countries. Many are now able to enjoy the tourist life for extended periods in the South of France by purchasing a second home. It’s also now possible to keep working in England as the LCCs make it affordable and possible to commute between their intercontinental homes. Through a review of issues and literature, the article will discuss the evolving air transportation heritage related to British tourism in the South of France. 

Vital exhaustion and risk for cancer

DEFF Research Database (Denmark)

Bergelt, Corinna; Christensen, Jane Hvarregaard; Prescott, Eva

2005-01-01

Vital exhaustion, defined as feelings of depression and fatigue, has previously been investigated mainly as a risk factor for cardiovascular disease. The authors investigated the association between depressive feelings and fatigue as covered by the concept of vital exhaustion and the risk...

Safe transport of radioactive material

International Nuclear Information System (INIS)

1994-01-01

Delivering radioactive material to where it is needed is a vital service to industry and medicine. Millions of packages are shipped all over the world by all modes of transport. The shipments pass through public places and must meet stringent safety requirements. This video explains how radioactive material is safely transported and describes the rules that carriers and handlers must follow

Large-scale transportation network congestion evolution prediction using deep learning theory.

Science.gov (United States)

Ma, Xiaolei; Yu, Haiyang; Wang, Yunpeng; Wang, Yinhai

2015-01-01

Understanding how congestion at one location can cause ripples throughout large-scale transportation network is vital for transportation researchers and practitioners to pinpoint traffic bottlenecks for congestion mitigation. Traditional studies rely on either mathematical equations or simulation techniques to model traffic congestion dynamics. However, most of the approaches have limitations, largely due to unrealistic assumptions and cumbersome parameter calibration process. With the development of Intelligent Transportation Systems (ITS) and Internet of Things (IoT), transportation data become more and more ubiquitous. This triggers a series of data-driven research to investigate transportation phenomena. Among them, deep learning theory is considered one of the most promising techniques to tackle tremendous high-dimensional data. This study attempts to extend deep learning theory into large-scale transportation network analysis. A deep Restricted Boltzmann Machine and Recurrent Neural Network architecture is utilized to model and predict traffic congestion evolution based on Global Positioning System (GPS) data from taxi. A numerical study in Ningbo, China is conducted to validate the effectiveness and efficiency of the proposed method. Results show that the prediction accuracy can achieve as high as 88% within less than 6 minutes when the model is implemented in a Graphic Processing Unit (GPU)-based parallel computing environment. The predicted congestion evolution patterns can be visualized temporally and spatially through a map-based platform to identify the vulnerable links for proactive congestion mitigation.

TESTING OF PULP VITALITY BY PULSOXIMETRY

Directory of Open Access Journals (Sweden)

Gabriela CIOBANU

2012-06-01

Full Text Available The methods applied for diagnosing the health condition of the pulp tissue are numerous, however, nowadays, an increasingly higher number of conventional tests are replaced by some objective, non-invasive, painless and reliable tests. Among them, pulse oximetry is a method for the investigation of pulp vitality based on oxygen saturation (SaO2 of the hemoglobin from the blood present in the pulp vascular bed, as a means of differentiating among the vital and the non-vital teeth. In the present study, registrations were made on a group of 120 frontal maxillary teeth, in patients with ages between 20 and 40 years, on using a digital sensor modified by the pulse oximeter with which the pulse and the values of oxygen saturation were measured at the level of both teeth and right hand finger. The mean SaO2 value in the pulp blood of the vital teeth was of 83.30% for the central incisor, of 78.51% for the lateral one and of 84.56%, respectively, for the canine; the value recorded at finger level was of 97%. In the non-vital teeth, the SaO2 value measured on the pulse oximeter was of 0%. Pulse registration showed mean values of 70.56 beatings/min at tooth level and of 70.88 beatings/min, respectively, at finger level. The results of the present study may confirm that pulse oximetry represents a simple, non-traumatic, efficient and objective method for testing the vitality condition of the dental pulp.

Vital exhaustion and risk for cancer

DEFF Research Database (Denmark)

Bergelt, Corinna; Christensen, Jane Hvarregaard; Prescott, Eva

2005-01-01

Vital exhaustion, defined as feelings of depression and fatigue, has previously been investigated mainly as a risk factor for cardiovascular disease. The authors investigated the association between depressive feelings and fatigue as covered by the concept of vital exhaustion and the risk...... for cancer....

Planetary Vital Signs

Science.gov (United States)

Kennel, Charles; Briggs, Stephen; Victor, David

2016-07-01

The climate is beginning to behave in unusual ways. The global temperature reached unprecedented highs in 2015 and 2016, which led climatologists to predict an enormous El Nino that would cure California's record drought. It did not happen the way they expected. That tells us just how unreliable temperature has become as an indicator of important aspects of climate change. The world needs to go beyond global temperature to a set of planetary vital signs. Politicians should not over focus policy on one indicator. They need to look at the balance of evidence. A coalition of scientists and policy makers should start to develop vital signs at once, since they should be ready at the entry into force of the Paris Agreement in 2020. But vital signs are only the beginning. The world needs to learn how to use the vast knowledge we will be acquiring about climate change and its impacts. Is it not time to use all the tools at hand- observations from space and ground networks; demographic, economic and societal measures; big data statistical techniques; and numerical models-to inform politicians, managers, and the public of the evolving risks of climate change at global, regional, and local scales? Should we not think in advance of an always-on social and information network that provides decision-ready knowledge to those who hold the responsibility to act, wherever they are, at times of their choosing?

Vital soil; function, value and properties

NARCIS (Netherlands)

Doelman, P.; Eijsackers, H.J.P.

2004-01-01

Healthy soil, with active soil life, deters long-term soil degradation and ensures that geo-physical processes are undisturbed. Is the vitality of soil under threat due to human civilization? Or is it due to contamination, intensification, and deforestation? Vital Soil aims to look at the effects

Charge transport in nanoscale "all-inorganic" networks of semiconductor nanorods linked by metal domains.

Science.gov (United States)

Lavieville, Romain; Zhang, Yang; Casu, Alberto; Genovese, Alessandro; Manna, Liberato; Di Fabrizio, Enzo; Krahne, Roman

2012-04-24

Charge transport across metal-semiconductor interfaces at the nanoscale is a crucial issue in nanoelectronics. Chains of semiconductor nanorods linked by Au particles represent an ideal model system in this respect, because the metal-semiconductor interface is an intrinsic feature of the nanosystem and does not manifest solely as the contact to the macroscopic external electrodes. Here we investigate charge transport mechanisms in all-inorganic hybrid metal-semiconductor networks fabricated via self-assembly in solution, in which CdSe nanorods were linked to each other by Au nanoparticles. Thermal annealing of our devices changed the morphology of the networks and resulted in the removal of small Au domains that were present on the lateral nanorod facets, and in ripening of the Au nanoparticles in the nanorod junctions with more homogeneous metal-semiconductor interfaces. In such thermally annealed devices the voltage dependence of the current at room temperature can be well described by a Schottky barrier lowering at a metal semiconductor contact under reverse bias, if the spherical shape of the gold nanoparticles is considered. In this case the natural logarithm of the current does not follow the square-root dependence of the voltage as in the bulk, but that of V(2/3). From our fitting with this model we extract the effective permittivity that agrees well with theoretical predictions for the permittivity near the surface of CdSe nanorods. Furthermore, the annealing improved the network conductance at cryogenic temperatures, which could be related to the reduction of the number of trap states.

Femoral head vitality after intracapsular hip fracture

International Nuclear Information System (INIS)

Stroemqvist, B.

1983-01-01

Femoral head vitality before, during and at various intervals from the operation was determined by tetracycline labeling and/or 99 sp (m)Tc-MDP scintimetry. In a three-year follow-up, healing prognosis could be determined by scintimetry 3 weeks from operation; deficient femoral head vitality predicting healing complications and retained vitality predicting uncomplicated healing. A comparison between pre- and postoperative scintimetry indicated that further impairment of the femoral head vitality could be caused by the operative procedure, and as tetracycline labeling prior to and after fracture reduction in 370 fractures proved equivalent, it was concluded that the procedure of osteosynthesis probably was responsible for capsular vessel injury, using a four-flanged nail. The four-flanged nail was compared with a low-traumatic method of osteosynthesis, two hook-pins, in a prospective randomized 14 month study, and the postoperative femoral head vitality was significantly better in the hook-pin group. This was also clearly demonstrated in a one-year follow-up for the fractures included in the study. Parallel to these investigations, the reliability of the methods of vitality determination was found satisfactory in methodologic studies. For clinical purpose, primary atraumatic osteosynthesis, postoperative prognostic scintimetry and early secondary arthroplasty when indicated, was concluded to be the appropriate approach to femoral neck fracture treatment. (Author)

The vital role of industry in contributing to the IAEA transport regulations

International Nuclear Information System (INIS)

Owen, G.

2004-01-01

Industry has taken a key role in the development of radioactive transport regulation for many years. There are two main parties that need consideration in the regulatory process: the 'public and worker' interest, this responsibility is represented by the regulators: the 'industry' interest, these parties by their nature, give priority to representing their own interests. Any amendment or review of the regulations benefits greatly from the industry perspective. The opposite ends of the 'spectrum of opinion' suggests that insufficient industry involvement may lead to uneconomic transport, whereas, insufficient Competent Authority involvement may lead to unsafe transport. These seemingly polarised views are considered and discussed, but it becomes clear that the two parties complement each other, both ensuring each remains grounded. The basis for a regulation that compares the costs directly with the benefit in terms of reduced risk to the public or employees is at the heart of successful regulation. This balance is fragile and sensitive and underlines the importance of a harmonised approach by both Industry and Competent Authorities

The vital role of industry in contributing to the IAEA transport regulations

Energy Technology Data Exchange (ETDEWEB)

Owen, G. [BNFL (United Kingdom)

2004-07-01

Industry has taken a key role in the development of radioactive transport regulation for many years. There are two main parties that need consideration in the regulatory process: the 'public and worker' interest, this responsibility is represented by the regulators: the 'industry' interest, these parties by their nature, give priority to representing their own interests. Any amendment or review of the regulations benefits greatly from the industry perspective. The opposite ends of the 'spectrum of opinion' suggests that insufficient industry involvement may lead to uneconomic transport, whereas, insufficient Competent Authority involvement may lead to unsafe transport. These seemingly polarised views are considered and discussed, but it becomes clear that the two parties complement each other, both ensuring each remains grounded. The basis for a regulation that compares the costs directly with the benefit in terms of reduced risk to the public or employees is at the heart of successful regulation. This balance is fragile and sensitive and underlines the importance of a harmonised approach by both Industry and Competent Authorities.

The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.

Science.gov (United States)

Sag, Duygu; Cekic, Caglar; Wu, Runpei; Linden, Joel; Hedrick, Catherine C

2015-02-27

ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here we demonstrate a role of ABCG1 as a mediator of tumour immunity. Abcg1(-/-) mice have dramatically suppressed subcutaneous MB49-bladder carcinoma and B16-melanoma growth and prolonged survival. We show that reduced tumour growth in Abcg1(-/-) mice is myeloid cell intrinsic and is associated with a phenotypic shift of the macrophages from a tumour-promoting M2 to a tumour-fighting M1 within the tumour. Abcg1(-/-) macrophages exhibit an intrinsic bias towards M1 polarization with increased NF-κB activation and direct cytotoxicity for tumour cells in vitro. Overall, our study demonstrates that the absence of ABCG1 inhibits tumour growth through modulation of macrophage function within the tumour, and illustrates a link between cholesterol homeostasis and cancer.

Organic matter linked radionuclide transport in Boom clay - Phenomenological understanding and abstraction to PA

International Nuclear Information System (INIS)

Maes, N.; Bruggeman, C.; Liu, D.J.; Salah, S.; Van Laer, L.; Wang, L.; Weetjens, E.; Govaerts, J.; Marivoet, J.; Brassinnes, S.

2012-01-01

conducted transport studies, performed both under controlled conditions in the lab and in in-situ environment. Transport experiments were conducted to study on one hand the behaviour of DOM itself using natural DOM as well as 14 C- labelled DOM fractions of different sizes separated from Boom Clay pore water. Transport of DOM is investigated at large time- and spatial scale in an in-situ experiment in the HADES URL. These experiments enable us to obtain general migration parameters for DOM as well as some information on filtration processes. The behaviour of RN, from di- to pentavalent, with the affinity to from DOM complexes is investigated in long-term running column migration experiments either as single tracer or complexed with 14 C- labelled DOM, in so-called double-tracer experiments. The use of two radionuclide labels allows the migration behaviour of both the DOM and the RN to be investigated. From these experiments we were able to obtain information on the kinetic dissociation behaviour that influences the transport of the RN. Based on these and other detailed studies, a consistent phenomenological model was put forward and tested which describes the transport behaviour of the RN-DOM linked species. The model considers the radionuclide to be transported as an organic matter complex/colloid that slowly dissociates, and both the RN-DOM and the RN sorb to the solid phase. It was observed that the transport of a suite of RN with different chemical behaviour, but which all show strong affinity to DOM, (tri-, tetra-, pentavalent La/Ac as well as some fission products) can be described by this model and even with parameter ranges that are quite narrow. This model shows several advantages as a first step towards PA abstraction use i) it is process based, ii) it is easy to implement without oversimplification (limited number of parameters which are determined or verified independently), iii) seems applicable for all RN that associate with DOM with a rather narrow range of

Serotonin transporter gene-linked polymorphism affects detection of facial expressions.

Directory of Open Access Journals (Sweden)

Ai Koizumi

Full Text Available Previous studies have demonstrated that the serotonin transporter gene-linked polymorphic region (5-HTTLPR affects the recognition of facial expressions and attention to them. However, the relationship between 5-HTTLPR and the perceptual detection of others' facial expressions, the process which takes place prior to emotional labeling (i.e., recognition, is not clear. To examine whether the perceptual detection of emotional facial expressions is influenced by the allelic variation (short/long of 5-HTTLPR, happy and sad facial expressions were presented at weak and mid intensities (25% and 50%. Ninety-eight participants, genotyped for 5-HTTLPR, judged whether emotion in images of faces was present. Participants with short alleles showed higher sensitivity (d' to happy than to sad expressions, while participants with long allele(s showed no such positivity advantage. This effect of 5-HTTLPR was found at different facial expression intensities among males and females. The results suggest that at the perceptual stage, a short allele enhances the processing of positive facial expressions rather than that of negative facial expressions.

Intercontinental transport link between America and Asia; Interkontinentale Transportverbindung zwischen Amerika und Asien

Energy Technology Data Exchange (ETDEWEB)

Mueller, Arnd [Ingenieurbuero Rail Consult Mueller, Berlin (Germany); Kreynis, Zosim; Kunzewitsch, Felix; Schwarz, Michael

2009-07-01

Strategic partnerships as a basis for international relations constitute a policy tool that, at a time of growing globalisation, is increasingly gaining in importance in solving economic problems that arise between different countries. Seen in this light, the problem of a land transport link between the two continents and its joint construction needs to be on the agenda for the meeting between the Russian and US presidents. Russia is in a position to propose to the international community not only a solution for a global problem, but also a package of eco-friendly technologies for the construction of linear structures in nature reserves in the far north. This opportunity ought to be seized. (orig.)

J. Ortega y Gasset's Vital Reason and M. Heidegger'sExistential Analytic

Directory of Open Access Journals (Sweden)

Francesco de Nigris

2012-04-01

Full Text Available According to Heidegger, being cannot be taken as a blind starting point or belief. Ortega y Gasset’s critique of this approach to the problem of being reveals the distance between two perspectives that are, nevertheless, joined by the actual horizon they explore: human life. However, their results are different because the analysis of Dasein aims at discovering the general meaning of being, while Ortega’s conception of being as a belief, as a historical interpretation of life linked to a “way of thinking”, turns his analysis of vital reason into a personal project of salvation.

Apoptosis-linked Gene-2 (ALG-2)/Sec31 Interactions Regulate Endoplasmic Reticulum (ER)-to-Golgi Transport

Science.gov (United States)

Helm, Jared R.; Bentley, Marvin; Thorsen, Kevin D.; Wang, Ting; Foltz, Lauren; Oorschot, Viola; Klumperman, Judith; Hay, Jesse C.

2014-01-01

Luminal calcium released from secretory organelles has been suggested to play a regulatory role in vesicle transport at several steps in the secretory pathway; however, its functional roles and effector pathways have not been elucidated. Here we demonstrate for the first time that specific luminal calcium depletion leads to a significant decrease in endoplasmic reticulum (ER)-to-Golgi transport rates in intact cells. Ultrastructural analysis revealed that luminal calcium depletion is accompanied by increased accumulation of intermediate compartment proteins in COPII buds and clusters of unfused COPII vesicles at ER exit sites. Furthermore, we present several lines of evidence suggesting that luminal calcium affected transport at least in part through calcium-dependent interactions between apoptosis-linked gene-2 (ALG-2) and the Sec31A proline-rich region: 1) targeted disruption of ALG-2/Sec31A interactions caused severe defects in ER-to-Golgi transport in intact cells; 2) effects of luminal calcium and ALG-2/Sec31A interactions on transport mutually required each other; and 3) Sec31A function in transport required luminal calcium. Morphological phenotypes of disrupted ALG-2/Sec31A interactions were characterized. We found that ALG-2/Sec31A interactions were not required for the localization of Sec31A to ER exit sites per se but appeared to acutely regulate the stability and trafficking of the cargo receptor p24 and the distribution of the vesicle tether protein p115. These results represent the first outline of a mechanism that connects luminal calcium to specific protein interactions regulating vesicle trafficking machinery. PMID:25006245

Association of the serotonin transporter-linked polymorphic region genotype with lower bone mineral density.

Science.gov (United States)

Lapid, M I; Kung, S; Frye, M A; Biernacka, J M; Geske, J R; Drake, M T; Jankowski, M D; Clarke, B L

2017-08-22

The serotonin transporter-linked polymorphic region (5-HTTLPR) of the serotonin transporter gene (SLC6A4) S allele is linked to pathogenesis of depression and slower response to selective serotonin reuptake inhibitors (SSRIs); depression and SSRIs are independently associated with bone loss. We aimed to determine whether 5-HTTLPR was associated with bone loss. This cross-sectional study included psychiatric patients with both 5-HTTLPR analysis and bone mineral density (BMD) assessment (hip and spine Z-scores if age <50 years and T-scores if ⩾50 years). BMD association with 5-HTTLPR was evaluated under models with additive allele effects and dominant S allele effects using linear regression models. Patients were stratified by age (<50 and ⩾50 years) and sex. Of 3016 patients with 5-HTTLPR genotyping, 239 had BMD assessments. Among the younger patients, the S allele was associated with lower Z-scores at the hip (P=0.002, dominant S allele effects; P=0.004, additive allele effects) and spine (P=0.0006, dominant S allele effects; P=0.01, additive allele effects). In sex-stratified analyses, the association of the S allele with lower BMD in the younger patients was also significant in the subset of women (P⩽0.003 for both hip and spine BMD under the additive allele effect model). In the small group of men younger than 50 years, the S allele was marginally associated with higher spine BMD (P=0.05). BMD T-scores were not associated with 5-HTTLPR genotypes in patients 50 years or older. The 5-HTTLPR variants may modify serotonin effects on bone with sex-specific effects.

Nuclear fuel transport and particularly spent fuel transport

International Nuclear Information System (INIS)

Lenail, B.

1986-01-01

Nuclear material transport is an essential activity for COGEMA linking the different steps of the fuel cycle transport systems have to be safe and reliable. Spent fuel transport is more particularly examined in this paper because the development of reprocessing plant. Industrial, techmical and economical aspects are reviewed [fr

Hygienic aspects of safety vital activity support of servicemen and their families on the contaminated zone

International Nuclear Information System (INIS)

Greben'kov, S.V.; Zholus, B.I.

1996-01-01

Analysis of radiation-and-hygienic, radioecological and medical aspects of vital activity of servicemen and their families at the radioactive contaminated territories (RCT) after the Chernobyl NPP accident has shown that the life there is linked with the increased health risk. The paper presents the examination results of 2550 human beings, over 2100 samples of foods and of the environmental objects have been examined. The direct correlation link between the territory contamination density and Cs-137 content in foods was determined; additional radiation burden from foods through gastrointestinal tract was observed in case of the incorporated radiation of a human being. The values of dose radiation burden of the examined persons during their life at the RCT were estimated. The life at the RCT is linked with the morbidity,with growth of psychonoses, with the rearrangement of the immune system. 10 refs

Serotonin transporter genotype linked to adolescent substance use treatment outcome through externalizing behavior

Directory of Open Access Journals (Sweden)

Tammy eChung

2014-07-01

Full Text Available Meta-analyses suggest that the serotonin transporter linked polymorphic region (5-HTTLPR short (S allele, relative to the long (L allele, is associated with risk for alcohol dependence, particularly among individuals with early onset antisocial alcoholism. Youth in substance use treatment tend to show antisocial or externalizing behaviors, such as conduct problems, which predict worse treatment outcome. This study examined a pathway in which 5-HTTLPR genotype is associated with externalizing behavior, and the intermediate phenotype of externalizing behavior serves as a link between 5-HTTLPR genotype and substance use treatment outcome in youth. Adolescents (n=142 who were recruited from addictions treatment were genotyped for 5-HTTLPR polymorphisms (S and LG carriers vs. LALA, assessed for externalizing and internalizing behaviors shortly after starting treatment, and followed over 6-months. 5-HTTLPR genotype was not associated with internalizing behaviors, and was not directly associated with 6-month substance use outcomes. However, 5-HTTLPR genotype was associated with externalizing behaviors (S and LG > LALA, and externalizing behaviors predicted alcohol and marijuana problem severity at 6-month follow-up. Results indicated an indirect (p<.05 and non-specific (i.e., both alcohol and marijuana severity effect of 5-HTTLPR genotype on youth substance use treatment outcomes, with externalizing behaviors as an important linking factor. Adolescents in substance use treatment with low expressing (S and LG 5-HTTLPR alleles and externalizing behavior might benefit from intervention that addresses serotonergic functioning, externalizing behaviors, and substance use to improve outcomes.

Large-scale transportation network congestion evolution prediction using deep learning theory.

Directory of Open Access Journals (Sweden)

Xiaolei Ma

Full Text Available Understanding how congestion at one location can cause ripples throughout large-scale transportation network is vital for transportation researchers and practitioners to pinpoint traffic bottlenecks for congestion mitigation. Traditional studies rely on either mathematical equations or simulation techniques to model traffic congestion dynamics. However, most of the approaches have limitations, largely due to unrealistic assumptions and cumbersome parameter calibration process. With the development of Intelligent Transportation Systems (ITS and Internet of Things (IoT, transportation data become more and more ubiquitous. This triggers a series of data-driven research to investigate transportation phenomena. Among them, deep learning theory is considered one of the most promising techniques to tackle tremendous high-dimensional data. This study attempts to extend deep learning theory into large-scale transportation network analysis. A deep Restricted Boltzmann Machine and Recurrent Neural Network architecture is utilized to model and predict traffic congestion evolution based on Global Positioning System (GPS data from taxi. A numerical study in Ningbo, China is conducted to validate the effectiveness and efficiency of the proposed method. Results show that the prediction accuracy can achieve as high as 88% within less than 6 minutes when the model is implemented in a Graphic Processing Unit (GPU-based parallel computing environment. The predicted congestion evolution patterns can be visualized temporally and spatially through a map-based platform to identify the vulnerable links for proactive congestion mitigation.

Validation of the Subjective Vitality Scale and study of the vitality of elderly people according to their physical activity

Directory of Open Access Journals (Sweden)

Nuno Couto

2017-08-01

Full Text Available The main aim of the study was to validate the Portuguese version of the Subjective Vitality Scale - SVS for the Portuguese elderly population through of confirmatory factorial analysis. The existence of differences in the perception of subjective vitality among sufficiently active and insufficiently active older adults was also analyzed. A total of 309 Portuguese elderly (242 females, 67 males aged 60-90 years (M = 68.59, SD = 6.60 participated in this study. Of the total sample, 256 are sufficiently active, while 53 are insufficiently active. The results show that the model was adjusted to data in a satisfactory way (χ² = 28.95; df = 9; CFI = .97; TLI = .94; SRMR = .04; RMSEA = .08; RMSEA 90% CI = .05 - .12, and show a concurrent validity with the Portuguese version of the Satisfaction with Life Scale. The data obtained allow us concluding that the Portuguese version of the Subjective Vitality Scale can be used as a measure of subjective vitality in the Portuguese elderly population. It was also verified that the subjective perception of vitality is greater among individuals sufficiently active compared with their peers that do not reach the amount of practice of recommended physical activity.

Alabama Department of Transportation : research and development 2011 peer exchange.

Science.gov (United States)

2011-05-01

Research and development are key to safe and efficient transportation systems in our country. They have played a vital role in the advancements that have led to our current transportation system. Federal regulation (23 CRF 420 Subpart B) establishes ...

An evaluation of So language vitality in Thailand

Directory of Open Access Journals (Sweden)

Thomas M. Tehan

2017-07-01

Full Text Available This paper explores the vitality and endangerment of So [sss] speech communities in Thailand. Beginning with a review of sociolinguistic survey results for five So communities in Thailand to ascertain the likely need for vernacular language development in So, additional data to cover the rest of the So community are provided. The language vitality of the So communities in Thailand is then assessed using Expanded GIDS and the Sustainable Use Model (SUM, Lewis & Simons 20152, an expansion of the Graded Intergenerational Disruption Scale (GIDS, Fishman 1991. This vitality model indicates that many So villages display vigorous language vitality whereas other villages are threatened by language shift. Some initial efforts at revitalization and language development show promise. Several additional activities are suggested to enhance the vitality of the language and help the So to resist the regional trend towards language shift to Northeastern Thai (Isaan.

Investigation of anisotropic thermal transport in cross-linked polymers

Science.gov (United States)

Simavilla, David Nieto

Thermal transport in lightly cross-linked polyisoprene and polybutadine subjected to uniaxial elongation is investigated experimentally. We employ two experimental techniques to assess the effect that deformation has on this class of materials. The first technique, which is based on Forced Rayleigh Scattering (FRS), allows us to measure the two independent components of the thermal diffusivity tensor as a function of deformation. These measurements along with independent measurements of the tensile stress and birefringence are used to evaluate the stress-thermal and stress-optic rules. The stress-thermal rule is found to be valid for the entire range of elongations applied. In contrast, the stress-optic rule fails for moderate to large stretch ratios. This suggests that the degree of anisotropy in thermal conductivity depends on both orientation and tension in polymer chain segments. The second technique, which is based on infrared thermography (IRT), allows us to measure anisotropy in thermal conductivity and strain induced changes in heat capacity. We validate this method measurements of anisotropic thermal conductivity by comparing them with those obtained using FRS. We find excellent agreement between the two techniques. Uncertainty in the infrared thermography method measurements is estimated to be about 2-5 %. The accuracy of the method and its potential application to non-transparent materials makes it a good alternative to extend current research on anisotropic thermal transport in polymeric materials. A second IRT application allows us to investigate the dependence of heat capacity on deformation. We find that heat capacity increases with stretch ratio in polyisoprene specimens under uniaxial extension. The deviation from the equilibrium value of heat capacity is consistent with an independent set of experiments comparing anisotropy in thermal diffusivity and conductivity employing FRS and IRT techniques. We identify finite extensibility and strain

Probabilities of False Alarm for Vital Sign Detection on the Basis of a Doppler Radar System

Directory of Open Access Journals (Sweden)

Nguyen Thi Phuoc Van

2018-02-01

Full Text Available Vital detection on the basis of Doppler radars has drawn a great deal of attention from researchers because of its high potential for applications in biomedicine, surveillance, and finding people alive under debris during natural hazards. In this research, the signal-to-noise ratio (SNR of the remote vital-sign detection system is investigated. On the basis of different types of noise, such as phase noise, Gaussian noise, leakage noise between the transmitting and receiving antennae, and so on, the SNR of the system has first been examined. Then the research has focused on the investigation of the detection and false alarm probabilities of the system when the transmission link between the human and the radar sensor system took the Nakagami-m channel model. The analytical model for the false alarm and the detection probabilities of the system have been derived. The proposed theoretical models for the SNR and detection probability match with the simulation and measurement results. These theoretical models have the potential to be used as good references for the hardware development of the vital-sign detection radar sensor system.

Vital areas at nuclear power plants

International Nuclear Information System (INIS)

Cameron, D.F.

1985-01-01

Vital area analysis of nuclear power plants has been performed for the Nuclear Regulatory Commission by the Los Alamos National Laboratory from the late 1970's through the present. The Los Alamos Vital Area Study uses a fault-tree modeling technique to identify vital areas and equipment at nuclear power plants to determine their vulnerability. This technique has been applied to all operating plants and approximately one-half of those under construction in the US. All saboteur-induced loss-of-coolant accidents and transients and the systems needed to mitigate them are considered. As a result of this effort, security programs at nuclear power plants now include vulnerability studies that identify targets in a systematic manner, and thus unnecessary protection has been minimized. 1 ref., 8 figs., 1 tab

Health, vital goals, and central human capabilities.

Science.gov (United States)

Venkatapuram, Sridhar

2013-06-01

I argue for a conception of health as a person's ability to achieve or exercise a cluster of basic human activities. These basic activities are in turn specified through free-standing ethical reasoning about what constitutes a minimal conception of a human life with equal human dignity in the modern world. I arrive at this conception of health by closely following and modifying Lennart Nordenfelt's theory of health which presents health as the ability to achieve vital goals. Despite its strengths I transform Nordenfelt's argument in order to overcome three significant drawbacks. Nordenfelt makes vital goals relative to each community or context and significantly reflective of personal preferences. By doing so, Nordenfelt's conception of health faces problems with both socially relative concepts of health and subjectively defined wellbeing. Moreover, Nordenfelt does not ever explicitly specify a set of vital goals. The theory of health advanced here replaces Nordenfelt's (seemingly) empty set of preferences and society-relative vital goals with a human species-wide conception of basic vital goals, or 'central human capabilities and functionings'. These central human capabilities come out of the capabilities approach (CA) now familiar in political philosophy and economics, and particularly reflect the work of Martha Nussbaum. As a result, the health of an individual should be understood as the ability to achieve a basic cluster of beings and doings-or having the overarching capability, a meta-capability, to achieve a set of central or vital inter-related capabilities and functionings. © 2012 John Wiley & Sons Ltd.

Optimización del transporte de mercancías mediante el transporte marítimo de corta distancia

OpenAIRE

Ametller i Malfaz, Xavier

2007-01-01

El tema que se plantea en el estudio es el de la distribución de mercancías mediante el Transporte Marítimo de Corta Distancia (TMCD). El actual desequilibrio entre modos de transporte en la distribución de mercancías entre países de la Unión Europea ha llevado a la saturación las infraestructuras de transporte terrestres, especialmente las carreteras. Por este motivo, resulta de vital importancia analizar distintas alternativas de transporte más sostenibles y que racionalicen el ...

A worksite vitality intervention for older hospital workers to improve vitality work engegement, productivity ans sick leave: results of a randomized controlled trial

NARCIS (Netherlands)

Strijk, J.E.; Proper, K.I.; Meschelen, W. van; Beek, A. van der

2012-01-01

Objectives A worksite vitality intervention aiming to improve lifestyle behaviors could be an effective tool to keep older workers vital, and thereby prolong their labor participation. Therefore, this study evaluates the effectiveness of such an intervention on vitality, work engagement,

[The vitalism of Paul-Joseph Barthez (1734-1806)].

Science.gov (United States)

Han, Hee Jin

2010-06-30

In The Logic of Life (1970), Francois Jacob (1920- ), Nobel Prize laureate in Physiology or Medicine (1965), proclaimed the end of vitalism based on the concept of life. More than two decades before this capital sentence condemning vitalism was pronounced, Georges Canguilhem (1904-1995), a French philosopher of medicine, already acknowledged that eighteenth-century vitalism was scientifically retrograde and politically reactionary or counter-revolutionary insofar as it was rooted in the animism of Georg Ernst Stahl (1660-1734). The negative preconception of the term 'vitalism' came to be established as an orthodox view, since Claude Bernard (1813-1878) unfairly criticized contemporary vitalism in order to propagate his idea of experimental medicine. An eminent evolutionary biologist like Ernst Mayr (1904-2005) still defended similar views in This is Biology (1997), arguing that if vitalists were decisive and convincing in their rejection of the Cartesian model (negative heuristics), however they were equally indecisive and unconvincing in their own explanatory endeavors (positive heuristics). Historically speaking, vitalists came to the forefront for their outstanding criticism of Cartesian mechanism and physicochemical reductionism, while their innovative concepts and theories were underestimated and received much less attention. Is it true that vitalism was merely a pseudo-science, representing a kind of romanticism or mysticism in biomedical science? Did vitalists lack any positive heuristics in their biomedical research? Above all, what was actually the so.called 'vitalism'? This paper aims to reveal the positive heuristics of vitalism defined by Paul.Joseph Barthez (1734-1806) who was the founder of the vitalist school of Montpellier. To this end, his work and idea are introduced with regard to the vying doctrines in physiology and medicine. At the moment when he taught at the medical school of Montpellier, his colleagues advocated the mechanism of Rene

Quantum Transport: The Link between Standard Approaches in Superlattices

DEFF Research Database (Denmark)

Wacker, Andreas; Jauho, Antti-Pekka

1998-01-01

Theories describing electrical transport in semiconductor superlattices can essentially be divided in three disjoint categories: (i) transport in a miniband; (ii) hopping between Wannier-Stark ladders; and (iii) sequential tunneling. We present a quantum transport model, based on nonequilibrium G...

Co-evolution of transportation and land use : modeling historical dependencies in land use and transportation decision making.

Science.gov (United States)

2009-11-01

The interaction between land use and transportation has long been the central issue in urban and regional planning. Models of such : interactions provide vital information to support many public policy decisions, such as land supply, infrastructure p...

CDC Vital Signs: Progress on Childhood Obesity

Science.gov (United States)

... VitalSigns – Childhood Obesity [PSA – 0:60 seconds] VitalSigns – Obesidad en niños: [PODCAST – 1:15 minutes] Childhood Overweight ... Prevention and Control MedlinePlus – Obesity in Children MedlinePlus – Obesidad en niños Top of Page Get Email Updates ...

Vital Signs-Secondhand Smoke

Centers for Disease Control (CDC) Podcasts

This podcast is based on the February 2015 CDC Vital Signs report. Secondhand smoke kills more than 400 infants and 41,000 adult nonsmokers every year. Learn what can be done to prevent secondhand smoke exposure.

Trad. Daniele Vitale, Arquitectos portugueses. Identidade, nacionalidade, modernidade

OpenAIRE

Marnoto, Rita

2010-01-01

(2010. Trad.). Daniele Vitale, Arquitectos portugueses. Identidade, nacionalidade, modernidade, JA Jornal Arquitectos. Publicação Trimestral da Ordem dos Arquitectos Portugal, 237, 93-101. ISSN 0870 1504 Trad. Daniele Vitale

WHY DO LOGISTICS AND TRANSPORT MATTER FOR DEVELOPMENT

Directory of Open Access Journals (Sweden)

Nedelescu-Ionescu Daniela

2014-07-01

Full Text Available In face of the challenges of global competition, business firms are concentrating more on the needs of customers and seeking ways to reduce costs, improve quality and meet the ever-rising expectation of their customers. To these ends, many of them have identified logistics as an area to build cost and service advantages. Logistical activities have always been vital to organizations, and therefore business logistics and supply chain management represents a synthesis of many concepts, principles, and methods from the more traditional areas of production, purchasing, transportation, economics, as well as from the disciplines of applied mathematics, and organizational behaviour. It concentrates on important activities of management such as planning, organizing, and controlling, and also on a three-way relationship of related transportation, inventory, and location strategies, which are at the heart of good logistics planning and decision making. Selecting a good logistics strategy may yield a competitive advantage. Transportation provides the flow of materials, products and persons between production facilities, warehouses, distribution centers, terminals and customer locations. The progress in techniques and management principles improves the moving load, delivery speed, service quality, operation costs, the usage of facilities and energy saving. A strong system needs a clear frame of logistics and a proper transport implements and techniques to link the producing procedures. The transportation takes a crucial part in the management of logistic. Without well-developed transportation systems, logistics could not bring its advantages into full play. A good transport system in logistics activities could provide better logistics efficiency, reduce operation cost, and promote service quality. The process determines the efficiency of moving products and energy saving. Improvements in transportation and logistics make valuable contribution to production

Serotonin transporter linked polymorphic region (5-HTTLPR) genotype moderates the longitudinal impact of early caregiving on externalizing behavior.

Science.gov (United States)

Brett, Zoë H; Humphreys, Kathryn L; Smyke, Anna T; Gleason, Mary Margaret; Nelson, Charles A; Zeanah, Charles H; Fox, Nathan A; Drury, Stacy S

2015-02-01

We examined caregiver report of externalizing behavior from 12 to 54 months of age in 102 children randomized to care as usual in institutions or to newly created high-quality foster care. At baseline no differences by group or genotype in externalizing were found. However, changes in externalizing from baseline to 42 months of age were moderated by the serotonin transporter linked polymorphic region genotype and intervention group, where the slope for short-short (S/S) individuals differed as a function of intervention group. The slope for individuals carrying the long allele did not significantly differ between groups. At 54 months of age, S/S children in the foster care group had the lowest levels of externalizing behavior, while children with the S/S genotype in the care as usual group demonstrated the highest rates of externalizing behavior. No intervention group differences were found in externalizing behavior among children who carried the long allele. These findings, within a randomized controlled trial of foster care compared to continued care as usual, indicate that the serotonin transporter linked polymorphic region genotype moderates the relation between early caregiving environments to predict externalizing behavior in children exposed to early institutional care in a manner most consistent with differential susceptibility.

The cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P

International Nuclear Information System (INIS)

Fuchs, Robert; Stracke, Anika; Ebner, Nadine; Zeller, Christian Wolfgang; Raninger, Anna Maria; Schittmayer, Matthias; Kueznik, Tatjana; Absenger-Novak, Markus; Birner-Gruenberger, Ruth

2015-01-01

Since the α1-adrenergic antagonist prazosin (PRZ) was introduced into medicine as a treatment for hypertension and benign prostate hyperplasia, several studies have shown that PRZ induces apoptosis in various cell types and interferes with endocytotic trafficking. Because PRZ is also able to induce apoptosis in malignant cells, its cytotoxicity is a focus of interest in cancer research. Besides inducing apoptosis, PRZ was shown to serve as a substrate for an amine uptake mechanism originally discovered in neurones called transport-P. In line with our hypothesis that transport-P is an endocytotic mechanism also present in non-neuronal tissue and linked to the cytotoxicity of PRZ, we tested the uptake of QAPB, a fluorescent derivative of PRZ, in cancer cell lines in the presence of inhibitors of transport-P and endocytosis. Early endosomes and lysosomes were visualised by expression of RAB5-RFP and LAMP1-RFP, respectively; growth and viability of cells in the presence of PRZ and uptake inhibitors were also tested. Cancer cells showed co-localisation of QAPB with RAB5 and LAMP1 positive vesicles as well as tubulation of lysosomes. The uptake of QAPB was sensitive to transport-P inhibitors bafilomycin A1 (inhibits v-ATPase) and the antidepressant desipramine. Endocytosis inhibitors pitstop ® 2 (general inhibitor of endocytosis), dynasore (dynamin inhibitor) and methyl-β-cyclodextrin (cholesterol chelator) inhibited the uptake of QAPB. Bafilomycin A1 and methyl-β-cyclodextrin but not desipramine were able to preserve growth and viability of cells in the presence of PRZ. In summary, we confirmed the hypothesis that the cellular uptake of QAPB/PRZ represents an endocytotic mechanism equivalent to transport-P. Endocytosis of QAPB/PRZ depends on a proton gradient, dynamin and cholesterol, and results in reorganisation of the LAMP1 positive endolysosomal system. Finally, the link seen between the cellular uptake of PRZ and cell death implies a still unknown pro

49 CFR 238.207 - Link between coupling mechanism and car body.

Science.gov (United States)

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Link between coupling mechanism and car body. 238.207 Section 238.207 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL... Requirements for Tier I Passenger Equipment § 238.207 Link between coupling mechanism and car body. All...

Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8

DEFF Research Database (Denmark)

Kniazeff, Julie; Loland, Claus Juul; Goldberg, Naomi

2005-01-01

The extracellular concentration of the neurotransmitters dopamine, serotonin, norepinephrine, GABA and glycine is tightly controlled by plasma membrane transporters belonging to the SLC6 gene family. A very large number of putative transport proteins with a remarkable homology to the SLC6...... proximity between TM 7 and 8 in the tertiary structure of TnaT as previously suggested for the mammalian counterparts. Furthermore, the inhibition of uptake upon cross-linking the two cysteines provides indirect support for a conserved conformational role of these transmembrane domains in the transport...

Electron transport in disordered films of metal nanoparticles linked by organic molecules

International Nuclear Information System (INIS)

Mueller, K.H.; Wei, G.; Herrmann, J.; Raguse, B.; Baxter, G.

2004-01-01

Full text: We have investigated theoretically and experimentally the mechanism of electron transport in films made of ∼10 nm sized gold nanoparticles linked by alkanedithiol molecules. Conduction in these films is due to linker-molecule assisted single-electron tunnelling between neighbouring nanoparticles where electrons have to overcome the Coulomb blockade energy. Strong disorder in our films in the form of separation gap fluctuations between adjacent nanoparticles and variations in Coulomb blockade energies cause electron current percolation. We have found that the dependence of the conduction on the length of the alkanedithiol molecules is affected by the degree of disorder. In addition, we have observed that percolation leads to a non-Arrhenius-like temperature dependence of the conduction and to a film-thickness dependent conductivity. I-V characteristics at low temperatures reveal Coulomb blockade effects. The strong dependence of the electrical conduction on the separation gaps between adjacent nanoparticles can be utilized in strain gauge and gas sensor applications

Assessment of prehospital medical care for the patients transported to emergency department by ambulance

Directory of Open Access Journals (Sweden)

Sehnaz Akın Paker

2015-09-01

Full Text Available Objectives: In our study we aimed to investigate the quality and quantity of medical management inside ambulances for 14 and over 14 years old patients transported to a level three emergency department (ED. Material and methods: Our study was conducted prospectively at a level three ED. 14 and over 14 years old patients who were transported to the ED by ambulance were included in the study consecutively. “Lack of vital rate” was described as missing of one or more of five vital rates during ambulance transportation. Both of two attending emergency physicians evaluated the medical procedures and management of patients at the ambulance simultaneously and this was recorded on the study forms. Results: Four hundred and fifty six patients were included in the study. Missing vital signs were identified for 90.1% (n = 322 of the patients that were transported by physicians and 92.4% (n = 73 of the patients that were transported by paramedics. For five patients with cardiac arrest two (33.3% had cardiopulmonary resuscitation (CPR, one (20% was intubated, one (20% received adrenaline. Out of 120 patients, needed spinal immobilization, 69 (57.5% had spinal board. Cervical collar usage was 65.1% (n = 69 We have revealed that 316 (69.3% patients did not receive at least one of the necessary medical intervention or treatment. Conclusion: During ambulance transportation, life-saving procedures like cardiopulmonary resuscitation, vital sign measurement, crucial treatment administration, endotracheal intubation, defibrillation, fracture immobilization were not performed adequately. Increasing the training on the deficient interventions and performing administrative inspections may improve quality of patient care. Keywords: Emergency department, Ambulance, Prehospital emergency care

Wallops Low Elevation Link Analysis for the Constellation Launch/Ascent Links

Science.gov (United States)

Cheung, Keith; Ho, C.; Kantak, A.; Lee, C.; Tye, R.; Richards, E.; Sham, C.; Schlesinger, A.; Barritt, B.

2011-01-01

To execute the President's Vision for Space Exploration, the Constellation Program (CxP) was formed to build the next generation spacecraft Orion and launch vehicles Ares, to transport human and cargo to International Space Station (ISS), moon, and Mars. This paper focuses on the detailed link analysis for Orion/Ares s launch and ascent links with Wallops 11.3m antenna (1) Orion's Dissimilar Voice link: 10.24 Kbps, 2-way (2) Ares Developmental Flight Instrument link, 20 Mbps, downlink. Three launch trajectories are considered: TD7-E, F (Feb), and G (Aug). In certain launch scenarios, the critical events of main engine cutoff (MECO) and Separation occur during the low elevation regime of WFF s downrange -- less than 5 degree elevation angle. The goal of the study is to access if there is enough link margins for WFF to track the DV and DFI links.

Sodium-Glucose linked transporter 2 (SGLT2) inhibitors--fighting diabetes from a new perspective.

Science.gov (United States)

Angelopoulos, Theodoros P; Doupis, John

2014-06-01

Sodium-Glucose linked transporter 2 (SGLT2) inhibitors are a new family of antidiabetic pharmaceutical agents whose action is based on the inhibition of the glucose reabsorption pathway, resulting in glucosuria and a consequent reduction of the blood glucose levels, in patients with type 2 diabetes mellitus. Apart from lowering both fasting and postprandial blood glucose levels, without causing hypoglycemia, SGLT2 inhibitors have also shown a reduction in body weight and the systolic blood pressure. This review paper explores the renal involvement in glucose homeostasis providing also the latest safety and efficacy data for the European Medicines Agency and U.S. Food and Drug Administration approved SGLT2 inhibitors, looking, finally, into the future of this novel antidiabetic category of pharmaceutical agents.

Transceptors as a functional link of transporters and receptors

Directory of Open Access Journals (Sweden)

George Diallinas

2017-03-01

Full Text Available Cells need to communicate with their environment in order to obtain nutrients, grow, divide and respond to signals related to adaptation in changing physiological conditions or stress. A very basic question in biology is how cells, especially of those organisms living in rapidly changing habitats, sense their environment. Apparently, this question is of particular importance to all free-living microorganisms. The critical role of receptors, transporters and channels, transmembrane proteins located in the plasma membrane of all types of cells, in signaling environmental changes is well established. A relative newcomer in environment sensing are the so called transceptors, membrane proteins that possess both solute transport and receptor-like signaling activities. Now, the transceptor concept is further enlarged to include micronutrient sensing via the iron and zinc high-affinity transporters of Saccharomyces cerevisiae. Interestingly, what seems to underline the transport and/or sensing function of receptors, transporters and transceptors is ligand-induced conformational alterations recognized by downstream intracellular effectors.

[Effects of exercise and physical activity on vital age].

Science.gov (United States)

Tanaka, Kiyoji; Matsuo, Tomoaki

2009-07-01

Advances in medical care have enabled many middle-aged and older adults to live for long periods of time. However, considerable variability is present among those people with regards to both longevity and physical health status. Physical inactivity is a significant risk factor for many chronic diseases, while exercise habituation is beneficial for the maintenance of good health and high vitality. The authors have developed the concept of so-called vital age for the assessment of health and functional status in middle-aged and older adults. The vital age is estimated using a variety of bio-medical, primarily cardiovascular risk factor parameters. Previous research has compared vital age between sedentary persons and those with obesity and chronic diseases and between sedentary persons and those with exercise habituation, and found that exercise habituation can certainly contribute to better physical vitality in previously sedentary persons as well as diseased persons.

Incorporating security into the transportation planning process.

Science.gov (United States)

2009-03-01

The transportation system is an important network established to ensure the mobility of people and goods between destinations. In addition, it also serves a vital role in responding to disasters, and therefore deserves special attention when those di...

The human dopamine transporter forms a tetramer in the plasma membrane: cross-linking of a cysteine in the fourth transmembrane segment is sensitive to cocaine analogs.

Science.gov (United States)

Hastrup, Hanne; Sen, Namita; Javitch, Jonathan A

2003-11-14

Using cysteine cross-linking, we demonstrated previously that the dopamine transporter (DAT) is at least a homodimer, with the extracellular end of transmembrane segment (TM) 6 at a symmetrical dimer interface. We have now explored the possibility that DAT exists as a higher order oligomer in the plasma membrane. Cysteine cross-linking of wild type DAT resulted in bands on SDS-PAGE consistent with dimer, trimer, and tetramer, suggesting that DAT forms a tetramer in the plasma membrane. A cysteine-depleted DAT (CD-DAT) into which only Cys243 or Cys306 was reintroduced was cross-linked to dimer, suggesting that these endogenous cysteines in TM4 and TM6, respectively, were cross-linked at a symmetrical dimer interface. Reintroduction of both Cys243 and Cys306 into CD-DAT led to a pattern of cross-linking indistinguishable from that of wild type, with dimer, trimer, and tetramer bands. This indicated that the TM4 interface and the TM6 interface are distinct and further suggested that DAT may exist in the plasma membrane as a dimer of dimers, with two symmetrical homodimer interfaces. The cocaine analog MFZ 2-12 and other DAT inhibitors, including benztropine and mazindol, protected Cys243 against cross-linking. In contrast, two substrates of DAT, dopamine and tyramine, did not significantly impact cross-linking. We propose that the impairment of cross-linking produced by the inhibitors results from a conformational change at the TM4 interface, further demonstrating that these compounds are not neutral blockers but by themselves have effects on the structure of the transporter.

A novel image database analysis system for maintenance of transportation facility : phase I.

Science.gov (United States)

2010-06-01

Transportation is critical to the global economy and plays a particularly vital role in this regions economic growth. Transportation infrastructures such as highways, streets, and bridges represent one of the largest public investments of many gov...

CDC Vital Signs: Legionnaires' Disease

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

Cyclic Vitalism

DEFF Research Database (Denmark)

Halse, Sven

2014-01-01

of taking such a unilateral view of what constituted a Vitalist concept of life. It could lead to a misunderstanding of Vitalist way of thinking, Rasch said, if the focus were only set upon the enthusiastic surplus, the worshipping of youth and health. To Vitalists, life is more than that. It is a totality...... of the era. The analyses include a further sub-categorisation to capture the different types of Life Force dealt with in the texts. By way of an introduction, Vitalism is discussed within the context of the scientific and social developments of the 19th Century....

Integrity of the iron transport process in mice with X-linked anaemia

International Nuclear Information System (INIS)

Thomson, A.B.R.; Valberg, L.S.

1975-01-01

The defect in iron (Fe) absorption in X-linked anaemia (sla) remains an enigma; absorption of a tracer dose of Fe is impaired in mice raised on an iron-containing cube diet but not in those raised on an iron-deficient diet. Because cobalt (Co) shares a similar intestinal transport pathway with Fe, a study was made of the effect of iron deficient diet on Co absorption. The duodenum of sla and genetically normal mice was perfused for 30 min with labelled solutions containing Co or Fe. Co uptake and transfer were similar in sla and normals fed cubes whereas Fe uptake and transfer were less in sla than in normals. The iron deficient diet caused an increase in the uptake and transfer of Co and Fe in sla and normals. When Co and Fe were perfused together in sla fed deficient diet, the uptake and transfer of each metal was less than when perfused alone. The distribution of Fe and Co in subcellular mucosal fractions was determined by a differential centrifugation technique. Deficient diet resulted in a directionally similar change in the subcellular distribution of Co and Fe in sla and normals. The increase in Co as well as Fe absorption in the sla on an iron deficient diet to the same high level found in genetically normal animals, and the inhibitory effect of each metal on the absorption of the other suggests that the absorption defect in sla is unlikely to be due to a primary defect in the function of the transport carrier. (author)

Microbiology and ecology are vitally important to premedical curricula

Science.gov (United States)

Smith, Val H.; Rubinstein, Rebecca J.; Park, Serry; Kelly, Libusha; Klepac-Ceraj, Vanja

2015-01-01

Despite the impact of the human microbiome on health, an appreciation of microbial ecology is yet to be translated into mainstream medical training and practice. The human microbiota plays a role in the development of the immune system, in the development and function of the brain, in digestion, and in host defense, and we anticipate that many more functions are yet to be discovered. We argue here that without formal exposure to microbiology and ecology—fields that explore the networks, interactions and dynamics between members of populations of microbes—vitally important links between the human microbiome and health will be overlooked. This educational shortfall has significant downstream effects on patient care and biomedical research, and we provide examples from current research highlighting the influence of the microbiome on human health. We conclude that formally incorporating microbiology and ecology into the premedical curricula is invaluable to the training of future health professionals and critical to the development of novel therapeutics and treatment practices. PMID:26198190

Productivity-based approach to valuation of transportation infrastructure.

Science.gov (United States)

2014-10-01

Transportation infrastructure, a vital component to sustain economic prosperity, represents the largest public-owned : infrastructure asset in the U.S. With over a trillion invested dollars invested into long-lived physical assets such as : roads and...

The transports of nuclear fuel cycle: An essential activity, safely managed

International Nuclear Information System (INIS)

Lenail, B.; Savornin, B.; Curtis, H.W.

1989-01-01

Transports associated with the nuclear fuel cycle normally use public means of transport by rail, road, sea and air and it might therefore be expected that they would be the Achilles heel of the cycle from a safety point of view. In fact, despite a few minor accidents, no radioactive releases resulting in a significant exposure of the public or the environment have occurred. On the other hand, during the last quarter, the news media have reported major spillages of crude oil and chemicals of high toxicity which have jeopardized the environment, the explosion of gas tankers with dozens of fatalities, and even the sinking of a nuclear submarine. All reports show that the radiation exposure to the public resulting from transports is negligible, i.e., far below 1% of that due to the whole nuclear industry. Similarly, the radiation exposure of transport workers has been lower than anticipated over several decades. The demonstrations and attacks by opponents of the nuclear industry against transports have been limited and have been used as an attempt to freeze the activity of different plants or disposal sites, and to focus public attention on the nuclear issue, rather than to question the fuel cycle transports themselves or the safety principles ruling them. When looking for explanations of such a favorable situation, which they should endeavour to perpetuate, without being surprised if any incident occurs, one finds two major reasons: First, the awareness by the fuel cycle operators, of the vital importance of a safe and reliable implementation of the necessary transports. Secondly, the results of assessments of safety conducted by international organizations and most countries, which have resulted in detailed international recommendations, as well as uniform national and modal regulations, thus establishing the necessary link between the basic rules for radioprotection and the needs of the Transport Industry

[Vital pulp therapy of damaged dental pulp].

Science.gov (United States)

Xuedong, Zhou; Dingming, Huang; Jianguo, Liu; Zhengwei, Huang; Xin, Wei; Deqin, Yang; Jin, Zhao; Liming, Chen; Lin, Zhu; Yanhong, Li; Jiyao, Li

2017-08-01

The development of an expert consensus on vital pulp therapy can provide practical guidance for the improvement of pulp damage care in China. Dental pulp disease is a major type of illness that adversely affects human oral health. Pulp capping and pulpotomy are currently the main methods for vital pulp therapy. Along with the development of minimal invasion cosmetic dentistry, using different treatment technologies and materials reasonably, preserving healthy tooth tissue, and extending tooth save time have become urgent problems that call for immediate solution in dental clinics. This paper summarizes the experiences and knowledge of endodontic experts. We develop a clinical path of vital pulp therapy for clinical work by utilizing the nature, approach, and degree of pulp damage as references, defense and self-repairing ability of pulp as guidance, and modern technologies of diagnosis and treatment as means.

Serotonin Transporter-Linked Polymorphic Region (5-HTTLPR) Genotype and Stressful Life Events Interact to Predict Preschool-Onset Depression: A Replication and Developmental Extension

Science.gov (United States)

Bogdan, Ryan; Agrawal, Arpana; Gaffrey, Michael S.; Tillman, Rebecca; Luby, Joan L.

2014-01-01

Background: Scientific enthusiasm about gene × environment interactions, spurred by the 5-HTTLPR (serotonin transporter-linked polymorphic region) × SLEs (stressful life events) interaction predicting depression, have recently been tempered by sober realizations of small effects and meta-analyses reaching opposing conclusions. These mixed findings…

Aging changes in vital signs

Science.gov (United States)

... this page: //medlineplus.gov/ency/article/004019.htm Aging changes in vital signs To use the sharing ... Normal body temperature does not change much with aging. But as you get older, it becomes harder ...

Re-vitalizing an indigenous language

DEFF Research Database (Denmark)

Hansen, Annette Skovsted

2014-01-01

The re-vitalization of indigenous languages depend on political and legal support and the imple-mentation of language rights depend on knowledge of vocabulary and grammar structures of the individual languages. Throughout the nineteenth century world, compilers of dictionaries adapted indigenous...... languages to match standards defined in nation-building and, thereby, enabled latent possibilities for indigenous populations to re-vitalize their languages in connection with the United Nations Year for Indigenous Peoples in 1993, and the first United Nations Decade for Indigenous Peoples, 1995......–2004. This article focuses on dictionaries of the languages of the Ainu populations in the borderlands between the nation-states Japan and Russia. The main argument is that the Ainu Cultural Promotion Act promulgated in 1997 had a significant impact on the production and purpose of Ainu dictionaries...

Transmission Characteristics on Wire-Driven Links of a Bridge Transported Servo Manipulator for the ACP Equipment Maintenance

International Nuclear Information System (INIS)

Park, Byung Suk; Jin, Jae Hyun; Song, Tae Gil; Kim, Sung Hyun; Yoon, Ji Sup

2004-01-01

A bridge transported servo manipulator (BTSM) system for the advanced spent fuel conditioning process (ACP) has been developed to overcome the limitation of access, which is a drawback of mechanical master-slave manipulators (MSM) for the equipment maintenance. The servo manipulator is composed of a slave manipulator attached to the telescoping tube sets equipped with the overhead bridge installed at a hot cell and a master manipulator installed at an out-of-hot cell. Each manipulator has 7 degrees-of-freedom (DOF): a body rotation, an upper-arm tilt, a lower-arm tilt, a lower-arm rotation, a wrist pan and tilt, and a grasp motion. A wire-driven mechanism for a lower-arm rotation, a wrist pan and tilt, and a grasp motion of the manipulator has been adopted to increase the handling capacity compared to the manipulator weight and decrease the friction. The main disadvantage of the wire-driven mechanism is that if one link is in motion, other links can be affected. In this paper, the transmission characteristics among the wire-driven links have been formulated to overcome this drawback. The unexpected behaviors are confirmed by analyses of transmission characteristics as well as experiments. Also, the experimental results show that the unexpected behaviors are greatly decreased by the proposed compensation equations

Transport link scanner: simulating geographic transport network expansion through individual investments

NARCIS (Netherlands)

Koopmans, C.C.; Jacobs, C.G.W.

2016-01-01

This paper introduces a GIS-based model that simulates the geographic expansion of transport networks by several decision-makers with varying objectives. The model progressively adds extensions to a growing network by choosing the most attractive investments from a limited choice set. Attractiveness

Structural and functional studies of conserved nucleotide-binding protein LptB in lipopolysaccharide transport

Energy Technology Data Exchange (ETDEWEB)

Wang, Zhongshan [Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park, NR4 7TJ (United Kingdom); College of Life Sciences, Sichuan University, Chengdu 610065 (China); Biomedical Sciences Research Complex, School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST (United Kingdom); Xiang, Quanju [College of Life Sciences, Sichuan University, Chengdu 610065 (China); Biomedical Sciences Research Complex, School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST (United Kingdom); Department of Microbiology, College of Resource and Environment Science, Sichuan Agriculture University, Yaan 625000 (China); Zhu, Xiaofeng [College of Life Sciences, Sichuan University, Chengdu 610065 (China); Dong, Haohao [Biomedical Sciences Research Complex, School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST (United Kingdom); He, Chuan [School of Electronics and Information, Wuhan Technical College of Communications, No. 6 Huangjiahu West Road, Hongshan District, Wuhan, Hubei 430065 (China); Wang, Haiyan; Zhang, Yizheng [College of Life Sciences, Sichuan University, Chengdu 610065 (China); Wang, Wenjian, E-mail: Wenjian166@gmail.com [Laboratory of Department of Surgery, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road II, Guangzhou, Guangdong 510080 (China); Dong, Changjiang, E-mail: C.Dong@uea.ac.uk [Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park, NR4 7TJ (United Kingdom)

2014-09-26

Highlights: • Determination of the structure of the wild-type LptB in complex with ATP and Mg{sup 2+}. • Demonstrated that ATP binding residues are essential for LptB’s ATPase activity and LPS transport. • Dimerization is required for the LptB’s function and LPS transport. • Revealed relationship between activity of the LptB and the vitality of E. coli cells. - Abstract: Lipopolysaccharide (LPS) is the main component of the outer membrane of Gram-negative bacteria, which plays an essential role in protecting the bacteria from harsh conditions and antibiotics. LPS molecules are transported from the inner membrane to the outer membrane by seven LPS transport proteins. LptB is vital in hydrolyzing ATP to provide energy for LPS transport, however this mechanism is not very clear. Here we report wild-type LptB crystal structure in complex with ATP and Mg{sup 2+}, which reveals that its structure is conserved with other nucleotide-binding proteins (NBD). Structural, functional and electron microscopic studies demonstrated that the ATP binding residues, including K42 and T43, are crucial for LptB’s ATPase activity, LPS transport and the vitality of Escherichia coli cells with the exceptions of H195A and Q85A; the H195A mutation does not lower its ATPase activity but impairs LPS transport, and Q85A does not alter ATPase activity but causes cell death. Our data also suggest that two protomers of LptB have to work together for ATP hydrolysis and LPS transport. These results have significant impacts in understanding the LPS transport mechanism and developing new antibiotics.

Structural and functional studies of conserved nucleotide-binding protein LptB in lipopolysaccharide transport

International Nuclear Information System (INIS)

Wang, Zhongshan; Xiang, Quanju; Zhu, Xiaofeng; Dong, Haohao; He, Chuan; Wang, Haiyan; Zhang, Yizheng; Wang, Wenjian; Dong, Changjiang

2014-01-01

Highlights: • Determination of the structure of the wild-type LptB in complex with ATP and Mg 2+ . • Demonstrated that ATP binding residues are essential for LptB’s ATPase activity and LPS transport. • Dimerization is required for the LptB’s function and LPS transport. • Revealed relationship between activity of the LptB and the vitality of E. coli cells. - Abstract: Lipopolysaccharide (LPS) is the main component of the outer membrane of Gram-negative bacteria, which plays an essential role in protecting the bacteria from harsh conditions and antibiotics. LPS molecules are transported from the inner membrane to the outer membrane by seven LPS transport proteins. LptB is vital in hydrolyzing ATP to provide energy for LPS transport, however this mechanism is not very clear. Here we report wild-type LptB crystal structure in complex with ATP and Mg 2+ , which reveals that its structure is conserved with other nucleotide-binding proteins (NBD). Structural, functional and electron microscopic studies demonstrated that the ATP binding residues, including K42 and T43, are crucial for LptB’s ATPase activity, LPS transport and the vitality of Escherichia coli cells with the exceptions of H195A and Q85A; the H195A mutation does not lower its ATPase activity but impairs LPS transport, and Q85A does not alter ATPase activity but causes cell death. Our data also suggest that two protomers of LptB have to work together for ATP hydrolysis and LPS transport. These results have significant impacts in understanding the LPS transport mechanism and developing new antibiotics

Vital Signs-Preventing Norovirus Outbreaks

Centers for Disease Control (CDC) Podcasts

This podcast is based on the June 2014 CDC Vital Signs report. Norovirus infects about 20 million Americans each year. Learn how to protect yourself and your family from this very contagious, potentially serious illness.

Radioactive materials transport: a story of steady technical improvement

International Nuclear Information System (INIS)

Price, M.

1991-01-01

The transport of radioactive material is a fundamental part of the nuclear industry and equally vital to the use of radioisotopes in medical diagnosis and therapy. The safety record is impressively good and this aids open discussion of the subject. An independent consultant formerly with Atomic Energy Authority Technology reports on the Second International Conference on Transportation for the Nuclear Industry. (Author)

Therapeutic touch: influence on vital signs of newborns.

Science.gov (United States)

Ramada, Nadia Christina Oliveira; Almeida, Fabiane de Amorim; Cunha, Mariana Lucas da Rocha

2013-12-01

To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit. This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch. The majority of newborns were male (n=28; 70%), pre-term (n=19; 52%) and born from vaginal delivery (n=27; 67%). Respiratory distress was the main reason for hospital admission (n=16; 40%). There was a drop in all vital signs after therapeutic touch, particularly in pain score, which had a considerable reduction in the mean values, from 3.37 (SD=1.31) to 0 (SD=0.0). All differences found were statistically significant by the Wilcoxon test (ptouch promotes relaxation of the baby, favoring reduction in vital signs and, consequently in the basal metabolism rate.

Provenance Usage in the OceanLink Project

Science.gov (United States)

Narock, T.; Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Fils, D.; Finin, T.; Hitzler, P.; Janowicz, K.; Jones, M.; Krisnadhi, A.; Lehnert, K. A.; Mickle, A.; Raymond, L. M.; Schildhauer, M.; Shepherd, A.; Wiebe, P. H.

2014-12-01

A wide spectrum of maturing methods and tools, collectively characterized as the Semantic Web, is helping to vastly improve thedissemination of scientific research. The OceanLink project, an NSF EarthCube Building Block, is utilizing semantic technologies tointegrate geoscience data repositories, library holdings, conference abstracts, and funded research awards. Provenance is a vital componentin meeting both the scientific and engineering requirements of OceanLink. Provenance plays a key role in justification and understanding when presenting users with results aggregated from multiple sources. In the engineering sense, provenance enables the identification of new data and the ability to determine which data sources to query. Additionally, OceanLink will leverage human and machine computation for crowdsourcing, text mining, and co-reference resolution. The results of these computations, and their associated provenance, will be folded back into the constituent systems to continually enhance precision and utility. We will touch on the various roles provenance is playing in OceanLink as well as present our use of the PROV Ontology and associated Ontology Design Patterns.

CLUB FORMATION MECHANISM FOR TRANSPORT-COMMUNITY CREDIT CARDS

Science.gov (United States)

Ding, Yue; Kobayashi, Kiyoshi; Nishida, Junji; Yoshida, Mamoru

In this paper, the roles of transport-community cards jointly issued by a public transport firm and retails are investigated as a means to vitalize an obsolescence shopping center located in a middle of a city. When both the price of goods supplied by the retails and the transport fares affect the consumers' behavior, there exist pecuniary externality between the behaviors of the retails and transport firms. The introduction of a transport-community cards system enables to integrate a basket of goods and transport service into a single commodity; thus, the pecuniary externality can be internalized by price coordination. In addition, the paper clarifies theoretically that the transport firm initiatively decides the price of the transportation service and the retails transfer their incomes to the transport firm so that they are induced to jointly issue the transport-community cards.

Vital Signs-Alcohol Poisoning Deaths

Centers for Disease Control (CDC) Podcasts

This podcast is based on the January 2015 CDC Vital Signs report. In the United States, an average of six people die every day from alcohol poisoning. Learn what you can do to prevent binge drinking and alcohol poisoning.

Superficie Específica y Estado Vital de la Materia

OpenAIRE

J. Hernando Ordoñez

1992-01-01

Se propone reemplazar el término de materia viva por el de estado vital de la materia por considerarlo adecuado, pues la materia es la misma, lo que cambia es su estado. Se estudia la relación entre la superficie específica y el estado vital de la materia. Constante del estado vital y el valor crítico de la superficie específica. Qué es la fuerza de inducción vital? Diferenciación funcional de las células. Cómo regula la unidad biológica su superficie específica? La materia que piens...

CDC Vital Signs-HIV Testing

Centers for Disease Control (CDC) Podcasts

This podcast is based on the December 2017 CDC Vital Signs report. In the U.S., about 15 percent of people who have HIV don't know they have it. Learn about the importance of testing, early diagnosis, and treatment.

CDC Vital Signs-Legionnaires' Disease

Centers for Disease Control (CDC) Podcasts

This podcast is based on the June 2017 CDC Vital Signs report. Legionnaires' disease is a serious, often deadly lung infection. People most commonly get it by breathing in water droplets containing Legionella germs. Learn how to prevent infections from Legionella.

Can we improve the clinical utility of respiratory rate as a monitored vital sign?

Science.gov (United States)

Chen, Liangyou; Reisner, Andrew T; Gribok, Andrei; McKenna, Thomas M; Reifman, Jaques

2009-06-01

Respiratory rate (RR) is a basic vital sign, measured and monitored throughout a wide spectrum of health care settings, although RR is historically difficult to measure in a reliable fashion. We explore an automated method that computes RR only during intervals of clean, regular, and consistent respiration and investigate its diagnostic use in a retrospective analysis of prehospital trauma casualties. At least 5 s of basic vital signs, including heart rate, RR, and systolic, diastolic, and mean arterial blood pressures, were continuously collected from 326 spontaneously breathing trauma casualties during helicopter transport to a level I trauma center. "Reliable" RR data were identified retrospectively using automated algorithms. The diagnostic performances of reliable versus standard RR were evaluated by calculation of the receiver operating characteristic curves using the maximum-likelihood method and comparison of the summary areas under the receiver operating characteristic curves (AUCs). Respiratory rate shows significant data-reliability differences. For identifying prehospital casualties who subsequently receive a respiratory intervention (hospital intubation or tube thoracotomy), standard RR yields an AUC of 0.59 (95% confidence interval, 0.48-0.69), whereas reliable RR yields an AUC of 0.67 (0.57-0.77), P support algorithms.

Vital Signs-Secondhand Smoke

Centers for Disease Control (CDC) Podcasts

2015-02-03

This podcast is based on the February 2015 CDC Vital Signs report. Secondhand smoke kills more than 400 infants and 41,000 adult nonsmokers every year. Learn what can be done to prevent secondhand smoke exposure.  Created: 2/3/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 2/3/2015.

Personalidad, resiliencia y satisfacción vital

OpenAIRE

Solo de Zaldívar del Amo, Paloma

2017-01-01

El presente trabajo analiza la relación existente entre resiliencia, satisfacción vital y las variables de personalidad extraversión, neuroticismo y piscoticismo. Para ello, se utilizó una muestra de 110 sujetos, todos ellos estudiantes de psicología que completaron los cuestionarios Escala de Resiliencia (RS-18), Versión Reducida del Cuestionario Revisado de Personalidad de Eysenck (EPQ-RA-24) y Cuestionario de Satisfacción Vital (SWLS) a través de la plataforma virtual de la Universidad de ...

Managing vital records in the Ghana Atomic Energy Commission

International Nuclear Information System (INIS)

Osei, Mary Mavis

2004-05-01

Several vital records can be found within the Ghana Atomic Energy Commission. Some of these records include confidential files on staff and general purpose files on staff, specialised subject files on IAEA, FAO, UN agencies etc, records on agreements from memorandum of understanding between the commission and other organisations, legislative instruments establishing the commission and its institutes and research publications. The study critically examined how these vital records at the Ghana Atomic Energy Commission were managed with the view of identifying problems and to propose actions for improvement. The specific objectives of the study was to examine methods of storage, security measures put in place to manage vital records, committment of management and staff to these measures, quality of records staff and vital records policy. Recommendations have been provided to help in the efficient and effective management of records in the commission. (A.B.)

Therapeutic touch: influence on vital signs of newborns

Science.gov (United States)

Ramada, Nadia Christina Oliveira; Almeida, Fabiane de Amorim; Cunha, Mariana Lucas da Rocha

2013-01-01

ABSTRACT Objective>: To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit. Methods: This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch. Results: The majority of newborns were male (n=28; 70%), pre-term (n=19; 52%) and born from vaginal delivery (n=27; 67%). Respiratory distress was the main reason for hospital admission (n=16; 40%). There was a drop in all vital signs after therapeutic touch, particularly in pain score, which had a considerable reduction in the mean values, from 3.37 (SD=1.31) to 0 (SD=0.0). All differences found were statistically significant by the Wilcoxon test (p<0.05). Conclusion: The results showed that therapeutic touch promotes relaxation of the baby, favoring reduction in vital signs and, consequently in the basal metabolism rate. PMID:24488378

ABC transporters of the wheat pathogen Mycosphaerella graminicola

NARCIS (Netherlands)

Zwiers, L.H.

2002-01-01

A TP- b inding c assette (ABC) transporters belong to one of the largest protein families known. They play a role in numerous vital processes in the cell and are characterised by their

Innovating for a competitive and resource-efficient transport system

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-05-15

Transport is vital to the economic prosperity and social integration of Europe. EU-transport policy is directed to developing a smart, efficient transport system with reduced dependency on fossil fuels and less environmental impacts that will enhance mobility in Europe and will underpin Europe's competitiveness in global markets. This includes the transport sector itself, which is an important part of the EU economy. In contributing to achieving these ambitious goals, extensive investments are made in research and development for sustainable and innovative solutions. This Policy Brochure, which is produced by the Transport Research and Innovation Portal (TRIP), highlights the contribution of research, development, and innovation in securing a competitive and resource-efficient transport system in Europe.

The relationship between obesity and forced vital capacity among university students.

Science.gov (United States)

Sun, Xugui; Chen, Xiaohong

2015-05-01

We sought to explore the relationship between vital capacity and obesity among university students in China. A cross-sectional study was designed to collect the routine health screening data for university students in 2013. The height, weight and force vital capacity of students were measured, and BMI was calculated with height and weight, so as to estimate the relationship between force vital capacity and obesity. Based on Working Group on Obesity references in China, obesity has a higher force vital capacity in both male and female university students. No correlation was found between vital capacity and BMI. obesity may have effect on pulmonary function among university students, which is a reference for further epidemic study. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

An Efficient Vital Area Identification Method

International Nuclear Information System (INIS)

Jung, Woo Sik

2017-01-01

A new Vital Area Identification (VAI) method was developed in this study for minimizing the burden of VAI procedure. It was accomplished by performing simplification of sabotage event trees or Probabilistic Safety Assessment (PSA) event trees at the very first stage of VAI procedure. Target sets and prevention sets are calculated from the sabotage fault tree. The rooms in the shortest (most economical) prevention set are selected and protected as vital areas. All physical protection is emphasized to protect these vital areas. All rooms in the protected area, the sabotage of which could lead to core damage, should be incorporated into sabotage fault tree. So, sabotage fault tree development is a very difficult task that requires high engineering costs. IAEA published INFCIRC/225/Rev.5 in 2011 which includes principal international guidelines for the physical protection of nuclear material and nuclear installations. A new efficient VAI method was developed and demonstrated in this study. Since this method drastically reduces VAI problem size, it provides very quick and economical VAI procedure. A consistent and integrated VAI procedure had been developed by taking advantage of PSA results, and more efficient VAI method was further developed in this study by inserting PSA event tree simplification at the initial stage of VAI procedure.

CDC Vital Signs-Heroin Epidemic

Centers for Disease Control (CDC) Podcasts

This podcast is based on the July 2015 CDC Vital Signs report. Heroin use and heroin-related overdose deaths are increasing. Most people are using it with other drugs, especially prescription opioid painkillers. Learn what can be done to prevent and treat the problem.

Diabetic Hyperglycemia: Link to Impaired Glucose Transport in Pancreatic β Cells

Science.gov (United States)

Unger, Roger H.

1991-03-01

Glucose uptake into pancreatic β cells by means of the glucose transporter GLUT-2, which has a high Michaelis constant, is essential for the normal insulin secretory response to hyperglycemia. In both autoimmune and nonautoimmune diabetes, this glucose transport is reduced as a consequence of down-regulation of the normal β-cell transporter. In autoimmune diabetes, circulating immunoglobulins can further impair this glucose transport by inhibiting functionally intact transporters. Insights into mechanisms of the unresponsiveness of β cells to hyperglycemia may improve the management and prevention of diabetes.

Driving innovation through big open linked data (BOLD) : Exploring antecedents using interpretive structural modelling

NARCIS (Netherlands)

Dwivedi, Yogesh K.; Janssen, M.F.W.H.A.; Slade, Emma L.; Rana, Nripendra P.; Weerakkody, Vishanth; Millard, Jeremy; Hidders, Jan; Snijders, D.

2016-01-01

Innovation is vital to find new solutions to problems, increase quality, and improve profitability. Big open linked data (BOLD) is a fledgling and rapidly evolving field that creates new opportunities for innovation. However, none of the existing literature has yet considered the

United States experience in the transportation of radioactive materials

International Nuclear Information System (INIS)

Platt, A.M.; Rhoads, R.E.; Hall, R.J.; Williams, L.D.; Brobst, W.A.; Shappert, L.B.; Jefferson, R.M.

1977-01-01

The transport of radioactive material forms a vital link in the nuclear fuel cycle in the United States. Actual U.S. experience and practice with such systems for the packaging and transport of uranium ore concentrates, uranium hexafluoride, fresh fuel, irradiated fuel, non-high-level waste, and plutonium with low heat generation rates are described. Specific shipping systems in current use for these services are illustrated. A comparison will be made of shipping requirements for nuclear parks versus dispersed facilities. Shipping systems for other fuel cycle materials (e.g., high-level waste and cladding hulls) have not been developed because there has been no need to transport these materials commercially. However, conceptual designs for packaging and transport of such materials have been developed. Selected systems are reviewed and summarized. Transport safety in the U.S. is regulated by the U.S. Department of Transportation and the Nuclear Regulatory Commission. Key regulations defining packaging requirements, allowable radiation dose rates, and handling procedures are reviewed. Although the radioactive material shipping industry has an outstanding safety record, opposition to nuclear fuel cycle shipments has surfaced in several areas. The U.S. congressional ban on the shipment of plutonium by air, the actions of New York City to prohibit certain shipments within the city limits, and the requirement of U.S. railroads to ship spent fuel casks only in dedicated trains are reviewed. In an attempt to provide information on the safety margins inherent in the design of radioactive materials packages, ERDA has undertaken a series of accident studies and full scale crash tests that stress the packages beyond the levels expected in severe accidents. In addition, the level of total risk associated with radioactive materials shipments is being evaluated. Current ERDA crash test and transportation risk assessment studies are reviewed. Concern about the possibility of

Transport logistical effects of new traffic infrastructures

DEFF Research Database (Denmark)

Hansen, Leif Gjesing

2004-01-01

The article examines the consequences for transport and logistics reorganisation following the establishment of fixed links across Great belt and Oresund in Denmark......The article examines the consequences for transport and logistics reorganisation following the establishment of fixed links across Great belt and Oresund in Denmark...

Causes and effects of vital instrumentation and control power supply bus failures

International Nuclear Information System (INIS)

Muhlheim, M.D.; Murphy, G.A.

1987-01-01

This article presents the results of a study in which the objective was to evaluate nuclear power-plant operating experience to identify the causes and the effects of vital instrumentation and control (I and C) power supply bus failures. Vital I and C power is normally provided to essential instrumentation and controls through either vital d-c or a-c power supply systems. The vital d-c power supply system generally provides control power for starting the diesel generators, for operating electrical circuit breakers, and for controlling various logic circuits. The vital d-c power system also supplies vital a-c power through an inverter. The vital a-c power supply system generally feeds the reactor protection system channels, the engineered safety features actuation system channels, and critical instrumentation in the control room. The leading cause of vital bus failures is inverter failures; other causes are human errors, battery charger failures, and miscellaneous failures. The effects of these failures are that the margin of safety can be degraded by (1) denying key information to the operators, (2) inducing plant transients, (3) causing safety injection actuations, and (4) causing the loss of shutdown cooling flow

Vital Sign Monitoring Through the Back Using an UWB Impulse Radar With Body Coupled Antennas.

Science.gov (United States)

Schires, Elliott; Georgiou, Pantelis; Lande, Tor Sverre

2018-04-01

Radar devices can be used in nonintrusive situations to monitor vital sign, through clothes or behind walls. By detecting and extracting body motion linked to physiological activity, accurate simultaneous estimations of both heart rate (HR) and respiration rate (RR) is possible. However, most research to date has focused on front monitoring of superficial motion of the chest. In this paper, body penetration of electromagnetic (EM) wave is investigated to perform back monitoring of human subjects. Using body-coupled antennas and an ultra-wideband (UWB) pulsed radar, in-body monitoring of lungs and heart motion was achieved. An optimised location of measurement in the back of a subject is presented, to enhance signal-to-noise ratio and limit attenuation of reflected radar signals. Phase-based detection techniques are then investigated for back measurements of vital sign, in conjunction with frequency estimation methods that reduce the impact of parasite signals. Finally, an algorithm combining these techniques is presented to allow robust and real-time estimation of both HR and RR. Static and dynamic tests were conducted, and demonstrated the possibility of using this sensor in future health monitoring systems, especially in the form of a smart car seat for driver monitoring.

Extending role by Japanese pharmacists after training for performing vital signs monitoring

Directory of Open Access Journals (Sweden)

Hasegawa F

2014-09-01

Full Text Available Background: In Japan, the circumstances in which pharmacists work are changing. Pharmacists are expected to assess conditions of patients subject to medication to ensure proper use of pharmaceutical products. To ensure fulfilment of these roles, there have already been pharmacists’ efforts in performing vital signs monitoring. Objective: To clarify the necessity and related issues, by investigating the state of vital sign monitoring in clinical field by pharmacists who have been trained in vital sign monitoring. Method: A web survey was conducted from 4th October to 3rd December 2012, subjecting 1,026 pharmacists who completed the vital signs training hosted by The Japanese Association of Home Care Pharmacies (JAHCP. Survey items were 1 basic information of a respondent, 2 situation of homecare conducted by pharmacists, 3 seminar attendance status, and 4 vital signs monitoring status after the seminar. Results: The number of valid respondents was 430 and the response rate was 41.9%. As a result of the present research, it was revealed that 168 pharmacists (41.4%, had the opportunity to perform vital signs monitoring. By conducting vital sign monitoring, effects such as 1 improved motivation of pharmacists and better communication with patients, 2 proper use of medication, and 3 cost reduction were confirmed. Conclusion: Judging from the results of the survey, pharmacists can improve medication therapy for patients by attaining vital sign skills and conduct vital sign monitoring. Pharmacists who perform vital sign monitoring should share cases where they experienced positive patient outcomes.

12 CFR 749.4 - Format for vital records preservation.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Format for vital records preservation. 749.4... RECORDS PRESERVATION PROGRAM AND APPENDICES-RECORD RETENTION GUIDELINES; CATASTROPHIC ACT PREPAREDNESS GUIDELINES § 749.4 Format for vital records preservation. Preserved records may be in any format that can be...

46 CFR 111.51-3 - Protection of vital equipment.

Science.gov (United States)

2010-10-01

...-GENERAL REQUIREMENTS Coordination of Overcurrent Protective Devices § 111.51-3 Protection of vital equipment. (a) The coordination of overcurrent protective devices must be demonstrated for all potential... 46 Shipping 4 2010-10-01 2010-10-01 false Protection of vital equipment. 111.51-3 Section 111.51-3...

Vital Signs-Preventing Teen Pregnancy

Centers for Disease Control (CDC) Podcasts

This podcast is based on the April 2015 CDC Vital Signs report. Teen births in the U.S. have declined, but still, more than 273,000 infants were born to teens ages 15 to 19 in 2013. Learn about the most effective types of birth control.

Associations between VO2max and vitality in older workers: a cross-sectional study

Directory of Open Access Journals (Sweden)

van der Beek Allard J

2010-11-01

Full Text Available Abstract Background To prevent early exit from work, it is important to study which factors contribute to healthy ageing. One concept that is assumed to be closely related to, and therefore may influence healthy ageing, is vitality. Vitality consists of both a mental and a physical component, and is characterised by a perceived high energy level, decreased feelings of fatigue, and feeling fit. Since VO2max gives an indication of one's aerobic fitness, which can be improved by increased levels of physical activity, and because feeling fit is one of the main characteristics of vitality, it is hypothesised that VO2max is related to vitality. Therefore, the aim of this study was to investigate the associations between VO2max and vitality. Methods In 427 older workers (aged 45 + years participating in the Vital@Work study, VO2max was estimated at baseline using the 2-km UKK walk test. Vitality was measured by both the UWES Vitality Scale and the RAND-36 Vitality Scale. Associations were analysed using linear regression analyses. Results The linear regression models, adjusted for age, showed a significant association between VO2max and vitality measured with the RAND-36 Vitality Scale (β = 0.446; 95% CI: 0.220-0.673. There was no significant association between VO2max and vitality measured with the UWES (β = -0.006; 95% CI:-0.017 - 0.006, after adjusting for age, gender and chronic disease status. Conclusions VO2max was associated with a general measure of vitality (measured with the RAND-36 Vitality Scale, but not with occupational health related vitality (measured with the UWES Vitality Scale. The idea that physical exercise can be used as an effective tool for improving vitality was supported in this study. Trial registration NTR1240

Associations between VO2max and vitality in older workers: a cross-sectional study.

Science.gov (United States)

Strijk, Jorien E; Proper, Karin I; Klaver, Linda; van der Beek, Allard J; van Mechelen, Willem

2010-11-09

To prevent early exit from work, it is important to study which factors contribute to healthy ageing. One concept that is assumed to be closely related to, and therefore may influence healthy ageing, is vitality. Vitality consists of both a mental and a physical component, and is characterised by a perceived high energy level, decreased feelings of fatigue, and feeling fit. Since VO2max gives an indication of one's aerobic fitness, which can be improved by increased levels of physical activity, and because feeling fit is one of the main characteristics of vitality, it is hypothesised that VO2max is related to vitality. Therefore, the aim of this study was to investigate the associations between VO2max and vitality. In 427 older workers (aged 45 + years) participating in the Vital@Work study, VO2max was estimated at baseline using the 2-km UKK walk test. Vitality was measured by both the UWES Vitality Scale and the RAND-36 Vitality Scale. Associations were analysed using linear regression analyses. The linear regression models, adjusted for age, showed a significant association between VO2max and vitality measured with the RAND-36 Vitality Scale (β = 0.446; 95% CI: 0.220-0.673). There was no significant association between VO2max and vitality measured with the UWES (β = -0.006; 95% CI:-0.017 - 0.006), after adjusting for age, gender and chronic disease status. VO2max was associated with a general measure of vitality (measured with the RAND-36 Vitality Scale), but not with occupational health related vitality (measured with the UWES Vitality Scale). The idea that physical exercise can be used as an effective tool for improving vitality was supported in this study. NTR1240.

Design and reliability, availability, maintainability, and safety analysis of a high availability quadruple vital computer system

Institute of Scientific and Technical Information of China (English)

Ping TAN; Wei-ting HE; Jia LIN; Hong-ming ZHAO; Jian CHU

2011-01-01

With the development of high-speed railways in China,more than 2000 high-speed trains will be put into use.Safety and efficiency of railway transportation is increasingly important.We have designed a high availability quadruple vital computer (HAQVC) system based on the analysis of the architecture of the traditional double 2-out-of-2 system and 2-out-of-3 system.The HAQVC system is a system with high availability and safety,with prominent characteristics such as fire-new internal architecture,high efficiency,reliable data interaction mechanism,and operation state change mechanism.The hardware of the vital CPU is based on ARM7 with the real-time embedded safe operation system (ES-OS).The Markov modeling method is designed to evaluate the reliability,availability,maintainability,and safety (RAMS) of the system.In this paper,we demonstrate that the HAQVC system is more reliable than the all voting triple modular redundancy (AVTMR) system and double 2-out-of-2 system.Thus,the design can be used for a specific application system,such as an airplane or high-speed railway system.

CDC Vital Signs-Preventing Melanoma

Centers for Disease Control (CDC) Podcasts

This podcast is based on the June 2015 CDC Vital Signs report. Skin cancer is the most common form of cancer in the U.S. In 2011, there were more than 65,000 cases of melanoma, the most deadly form of skin cancer. Learn how everyone can help prevent skin cancer.

Insights into the concept of vitality: associations with participation and societal costs.

Science.gov (United States)

van Steenbergen, E; van Dongen, J M; Wendel-Vos, G C W; Hildebrandt, V H; Strijk, J E

2016-04-01

In healthcare, the focus is currently shifting from someone's disabilities to someone's abilities, which is also evident from the increasing focus on vitality. Vitality (here defined as energy, motivation and resilience) is an often used concept, which also aims at someone's capabilities. However, little is known about vitality yet; in particular about its association with participation and societal costs. Within a cross-sectional design, information regarding vitality, participation and societal costs was collected among 8015 Dutch adults aged 20 years and over. Vitality was measured using the validated Dutch Vitality Questionnaire (Vita-16). Information on economic (i.e. want/able to work, work absenteeism, work performance), societal (i.e. voluntary work, informal care giving) and social participation (i.e. quantity and quality of social contacts) and societal costs (i.e. healthcare and work-related costs) was collected using an internet survey. Significant associations were found between vitality and various economic (i.e.sustainable employability:want to work: β = 1.21, 95% CI: 0.99-1.43,able to work:β = 2.09, 95% CI: 1.79-2.38;work absenteeism: OR = 0.75, 95% CI: 0.71-0.79;work performance:β = 0.49, 95% CI: 0.46-0.52), societal (i.e.voluntary work, informal care) and social (i.e.quantity and quality of social contacts) participation measures, as well as between vitality and societal costs (i.e.healthcare costs:β = -213.73, 95% CI: €-311.13 to €-107.08),absenteeism costs: β = -338.57, 95% CI: €-465.36 to €-214.14 and presenteeism costs:β = -1293.31, 95% CI: €-1492.69 to €-1088.95). This study showed significant positive associations between vitality and economic, societal and social participation and negative associations between vitality and societal costs. This may stimulate research on interventions enhancing and maintaining vitality and thereby contributing to improved participation and reduced costs. © The Author 2015. Published by

Energy and environmental norms on Minimum Vital Flux

International Nuclear Information System (INIS)

Maran, S.

2008-01-01

By the end of the year will come into force the recommendations on Minimum Vital flow and operators of hydroelectric power plants will be required to make available part of water of their derivations in order to protect river ecosystems. In this article the major energy and environmental consequences of these rules, we report some quantitative evaluations and are discusses the proposals for overcoming the weaknesses of the approach in the estimation of Minimum Vital Flux [it

A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans.

Science.gov (United States)

Knowlton, Wendy M; Hubert, Thomas; Wu, Zilu; Chisholm, Andrew D; Jin, Yishi

2017-01-01

The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP. Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo , we surveyed genes related to mitochondrial function for effects on axon regrowth after laser axotomy. Genes involved in mitochondrial transport, calcium uptake, mitophagy, or fission and fusion were largely dispensable for axon regrowth, with the exception of eat-3/Opa1 . Surprisingly, many genes encoding components of the electron transport chain were dispensable for regrowth, except for the iron-sulfur proteins gas-1, nduf-2.2, nduf-7 , and isp-1 , and the putative oxidoreductase rad-8 . In these mutants, axonal development was essentially normal and axons responded normally to injury by forming regenerative growth cones, but were impaired in subsequent axon extension. Overexpression of nduf-2.2 or isp-1 was sufficient to enhance regrowth, suggesting that mitochondrial function is rate-limiting in axon regeneration. Moreover, loss of function in isp-1 reduced the enhanced regeneration caused by either a gain-of-function mutation in the calcium channel EGL-19 or overexpression of the MAP kinase DLK-1. While the cellular function of RAD-8 remains unclear, our genetic analyses place rad-8 in the same pathway as other electron transport genes in axon regeneration. Unexpectedly, rad-8 regrowth defects were suppressed by altered function in the ubiquinone biosynthesis gene clk-1 . Furthermore, we found that inhibition of the mitochondrial unfolded protein response via deletion of atfs-1 suppressed the defective regrowth in nduf-2.2 mutants. Together, our data indicate that while axon regeneration is not significantly affected by general dysfunction of cellular respiration, it is sensitive to the proper functioning of a select subset of electron transport chain genes, or to the

Duelling Ontologies: Might Vitalism Offer Balance and Value?

Science.gov (United States)

Richards, Dennis; Emmanuel, Elizabeth; Grace, Sandra

This article is part of a project investigating chiropractors' beliefs on the role of vitalism in their philosophical and practice approaches and how that might contribute to addressing current epidemics of non-communicable diseases. It aims to present atomism, reductionism, materialism and mechanism as fundamental ontologies in biomedicine and to examine what role these might play in its struggle to deal with these epidemics; to present vitalism as a fundamental ontology existing in chiropractic along with these ontologies of biomedicine; and to discuss how imbalances in the use of these ontologies and practices stemming from them might be contributing to difficulties in addressing these epidemics. The use of more balanced approaches by chiropractors involving not only mechanistic biomedical ontologies but also an increased focus on vitalism might offer value in addressing these epidemics and should be investigated. Copyright © 2017 Elsevier Inc. All rights reserved.

The Vitality of Disease

OpenAIRE

Wahlberg, Ayo

2017-01-01

In recent decades, social scientists have carried out empirical studies in the laboratories, clinics and patient associations within and through which biological knowledge, biomedical practice, biosocialities and biological citizens are being co-produced. In this chapter, I sketch a novel analytics of what we might be conceptualised as the vitality of disease. Medical interventions are increasingly as much about improving (quality of) life as they are about saving and prolonging life. As a co...

Vital Signs - Child Passenger Safety

Centers for Disease Control (CDC) Podcasts

This podcast is based on the February 2014 CDC Vital Signs report. Over the past 10 years, more than 9,000 children 12 and under died in motor vehicle crashes, and a third who died in 2011 weren't buckled up. Buckling up is the best way to reduce injuries and save lives.

CDC Signos Vitales-Seguridad de los camioneros (Vital Signs-Trucker Safety)

Centers for Disease Control (CDC) Podcasts

2015-03-03

Este podcast se basa en la edición de marzo del 2015 del informe Signos Vitales de los CDC. En el 2012 en los Estados Unidos, ocurrieron cerca de 317 000 choques asociados a camiones pesados. Veintiséis mil camioneros y sus pasajeros sufrieron lesiones en esos choques, y cerca de 700 murieron. Infórmese sobre lo que se puede hacer para que los camioneros estén seguros.  Created: 3/3/2015 by National Institute for Occupational Safety and Health (NIOSH).   Date Released: 3/3/2015.

Vital capacity and COPD: the Swedish CArdioPulmonary bioImage Study (SCAPIS

Directory of Open Access Journals (Sweden)

Torén K

2016-05-01

Full Text Available Kjell Torén,1 Anna-Carin Olin,1 Anne Lindberg,2 Jenny Vikgren,3 Linus Schiöler,1 John Brandberg,3 Åse Johnsson,3 Gunnar Engström,4 H Lennart Persson,5 Magnus Sköld,6 Jan Hedner,7 Eva Lindberg,8 Andrei Malinovschi,8 Eeva Piitulainen,9 Per Wollmer,9 Annika Rosengren,10 Christer Janson,8 Anders Blomberg,2 Göran Bergström10 1Section of Occupational and Environmental Medicine, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 2Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine, Umeå University, Umeå, 3Department of Radiology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 4Department of Clinical Science, Malmö, Lund University, Lund, 5Department of Respiratory Medicine and Department of Medicine and Health Sciences, Linköping University, Linköping, 6Respiratory Medicine Unit, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, 7Department of Internal Medicine/Lung Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 8Department of Medical Sciences, Clinical Physiology and Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, 9Department of Translational Medicine, Lund University, Malmö, 10Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD is based on the ratio of forced expiratory volume in 1 second (FEV1/vital capacity (VC, either as a fixed value <0.7 or below the lower limit of normal (LLN. Forced vital capacity (FVC is a proxy for VC. The first aim was to compare the use of FVC and VC, assessed as the highest value of FVC or slow vital capacity (SVC, when assessing the FEV1/VC ratio in a general population

Reactor sabotage vulnerability and vital-equipment identification

International Nuclear Information System (INIS)

Boudreau, J.M.; Haarman, R.A.

1982-01-01

Two ongoing programs at Los Alamos, the Vital Area Analysis Program and the Reactor Sabotage Vulnerability Program, are discussed. The Laboratory has been providing the Nuclear Regulatory Commission with technical support in identifying the vital areas at nuclear power plants through the use of sabotage fault trees. This procedure is being expanded to provide support for the Reactor Sabotage Vulnerability Assessment Program. A re-examination of some of the original system modeling assumptions, including a survey of the applicable research, is underway. A description of the survey work and the computerized data bases being used is provided. This program is expected to result in refinements in the existing procedures

Evidence of fractional transport in point vortex flow

International Nuclear Information System (INIS)

Leoncini, Xavier; Kuznetsov, Leonid; Zaslavsky, George M.

2004-01-01

Advection properties of passive particles in flows generated by point vortices are considered. Transport properties are anomalous with characteristic transport exponent μ∼1.5. This behavior is linked back to the presence of coherent fractal structures within the flow. A fractional kinetic analysis allows to link the characteristic transport exponent μ to the trapping time exponent γ=1+μ. The quantitative agreement is found for different systems of vortices investigated and a clear signature is obtained of the fractional nature of transport in these flows

HUBUNGAN PEMAKAIAN ALAT PELINDUNG PERNAPASAN DENGAN TINGKAT KAPASITAS VITAL PARU

Directory of Open Access Journals (Sweden)

David Eko Rikmiarif

2012-07-01

Full Text Available Tujuan penelitian adalah untuk mengetahui hubungan antara pemakaian alat pelindung pernapasan dengan tingkat kapasitas vital paru pada pekerja pembuat genteng di Desa Singorojo Kabupaten Jepara tahun 2011. Jenis penelitian adalah penelitian analitik yang menjelaskan korelasi antara variabel bebas dan variabel terikat. Metode yang digunakan dalam penelitian ini adalah cross sectional. Teknik penarikan sampel menggunakan total sampling. Variabel penelitian terdiri dari variabel bebas yaitu pemakaian alat pelindung pernapasan, sedangkan variabel terikat adalah kapasitas vital paru. Teknik pengumpulan data dengan metode pengukuran, kuesioner, dan dokumentasi. Metode analisis data menggunakan analisis univariat dengan analisis deskriptif dan uji bivariat dengan spearman test melalui bantuan komputer. Hasil penelitian menunjukkan bahwa nilai korelasi spearman -0,923 dengan nilai probabilitas (p value 0,0001 (< 0,05, yang artinya bahwa tidak ada hubungan yang bermakna antara pemakaian alat pelindung pernapasan dengan tingkat kapasitas vital paru pada pekerja pembuat genteng di Desa Singorojo Kabupaten Jepara tahun 2011. Simpulan penelitian adalah ada ada hubungan antara praktik penggunaan APD pernafasan (masker dengan Tingkat Kapasitas Vital Paru. The research objective was to determine the relationship between the use of respiratory protective equipment with the level of vital lung capacity in workers in the village of tile maker Singorojo Jepara regency in 2011. This type of research was the analytical research that explains the correlation between independent variables and the dependent variable. The method used in this study was cross sectional. Sampling technique using total sampling. Variable study consists of the independent variable is the use of respiratory protective equipment, while the dependent variable was the vital lung capacity. Data collection techniques with methods of measurement, questionnaires, and documentation. Methods of data

Boron transport in plants: co-ordinated regulation of transporters

Science.gov (United States)

Miwa, Kyoko; Fujiwara, Toru

2010-01-01

Background The essentiality of boron (B) for plant growth was established >85 years ago. In the last decade, it has been revealed that one of the physiological roles of B is cross-linking the pectic polysaccharide rhamnogalacturonan II in primary cell walls. Borate cross-linking of pectic networks serves both for physical strength of cell walls and for cell adhesion. On the other hand, high concentrations of B are toxic to plant growth. To avoid deficiency and toxicity problems, it is important for plants to maintain their tissue B concentrations within an optimum range by regulating transport processes. Boron transport was long believed to be a passive, unregulated process, but the identification of B transporters has suggested that plants sense and respond to the B conditions and regulate transporters to maintain B homeostasis. Scope Transporters responsible for efficient B uptake by roots, xylem loading and B distribution among leaves have been described. These transporters are required under B limitation for efficient acquisition and utilization of B. Transporters important for tolerating high B levels in the environment have also been identified, and these transporters export B from roots back to the soil. Two types of transporters are involved in these processes: NIPs (nodulin-26-like intrinsic proteins), boric acid channels, and BORs, B exporters. It is demonstrated that the expression of genes encoding these transporters is finely regulated in response to B availability in the environment to ensure tissue B homeostasis. Furthermore, plants tolerant to stress produced by low B or high B in the environment can be generated through altered expression of these transporters. Conclusions The identification of the first B transporter led to the discovery that B transport was a process mediated not only by passive diffusion but also by transporters whose activity was regulated in response to B conditions. Now it is evident that plants sense internal and external B

Studies of cell kinetics in vital and necrotic tumor regions: Measurement of loss rate using 125iododeoxyuridine

International Nuclear Information System (INIS)

Porschen, R.

1981-01-01

The method of determining cell losses in situ from the decrease in radioactivity after a single i.p. injection of the thymidine-analogue, 125 iododeoxyuridine was tested for its applicability in different development stages of the solid mammary adenocarcinoma EO 771 on male C57 N1/6J mice. Invasive studies on activity distributions in vital and necrotic tumour regions were carried out after injection of Light Green SF. The following results were obtained: 1) External measurement of activity loss register the removal of labelled cells and decay products rather than cell death. The total activity of the tumour at any time following injection corresponds to the sum of radioactivity in the proliferating, non-growing and necrotic compartments. 2) In solid tumours, there are regions with differing transport capacity. 3) The method using 125 J-UdR does not allow determination of loss rates as a function of a given volume but rather yields an averaged value. 4) Activity losses of vital tumour cells largely correspond to the cell loss. (orig./MG) [de

Vital Signs-Preventing Norovirus Outbreaks

Centers for Disease Control (CDC) Podcasts

2014-06-03

This podcast is based on the June 2014 CDC Vital Signs report. Norovirus infects about 20 million Americans each year. Learn how to protect yourself and your family from this very contagious, potentially serious illness.  Created: 6/3/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 6/3/2014.

Monitor portátil de signos vitales con un PDA

OpenAIRE

Rodríguez Salazar, Rita Beatriz

2007-01-01

El monitor portátil de signos vitales facilita el proceso de medición y lleva un registro organizado de los valores medidos. Los signos vitales que se contempla son la temperatura corporal, la presión arterial y la frecuencia cardiaca.Para la medición de estos signos vitales se utilizan los sensores respectivos y se realiza el acondicionamiento de señal. Estas señales son procesadas en un PDA en el que también se visualiza los valores obtenidos en la medición y se registra estos datos si el u...

Vital pulp therapy in symptomatic immature permanent molars: Report of 3 cases

Directory of Open Access Journals (Sweden)

SheikhRezaie MS.

2009-11-01

Full Text Available "nEndodontic treatment of immature permanent teeth accompanies with several issues. The primary goal when treating such teeth is to maintain pulp vitality so that root development can occur normally. Indications and requirements for vital pulp therapy include asymptomatic and reversible pulpitis. Also there are controversial opinions regarding the ultimate clinical treatment of the vital pulp therapy techniques. In this manuscript we report 3 cases of immature symptomatic permanent molars with irreversible pulpitis caused by caries exposure of the pulp that have been undergone vital pulp therapy successfully.

DistancePPG: Robust non-contact vital signs monitoring using a camera

Science.gov (United States)

Kumar, Mayank; Veeraraghavan, Ashok; Sabharwal, Ashutosh

2015-01-01

Vital signs such as pulse rate and breathing rate are currently measured using contact probes. But, non-contact methods for measuring vital signs are desirable both in hospital settings (e.g. in NICU) and for ubiquitous in-situ health tracking (e.g. on mobile phone and computers with webcams). Recently, camera-based non-contact vital sign monitoring have been shown to be feasible. However, camera-based vital sign monitoring is challenging for people with darker skin tone, under low lighting conditions, and/or during movement of an individual in front of the camera. In this paper, we propose distancePPG, a new camera-based vital sign estimation algorithm which addresses these challenges. DistancePPG proposes a new method of combining skin-color change signals from different tracked regions of the face using a weighted average, where the weights depend on the blood perfusion and incident light intensity in the region, to improve the signal-to-noise ratio (SNR) of camera-based estimate. One of our key contributions is a new automatic method for determining the weights based only on the video recording of the subject. The gains in SNR of camera-based PPG estimated using distancePPG translate into reduction of the error in vital sign estimation, and thus expand the scope of camera-based vital sign monitoring to potentially challenging scenarios. Further, a dataset will be released, comprising of synchronized video recordings of face and pulse oximeter based ground truth recordings from the earlobe for people with different skin tones, under different lighting conditions and for various motion scenarios. PMID:26137365

Mediating Role of Mindfulness on the Associations of Friendship Quality and Subjective Vitality.

Science.gov (United States)

Akin, Umran; Akin, Ahmet; Uğur, Erol

2016-10-01

This research investigated the mediator role of mindfulness on the relationship between friendship quality and subjective vitality. Participants were 273 university students (M age = 21 years, SD = 1.1) who completed a questionnaire package that included the Friendship Quality Scale, the Cognitive and Affective Mindfulness Scale, and the Subjective Vitality Scale. Both mindfulness and subjective vitality were correlated positively with friendship quality and subjective vitality was correlated positively with mindfulness. Mindfulness mediated the relationship between friendship quality and subjective vitality. Together, the findings illuminate the importance of friendship quality in psychological and cognitive adjustment. © The Author(s) 2016.

CDC Vital Signs: Preventing Teen Pregnancy

Science.gov (United States)

... Press Kit Read the MMWR Science Clips Preventing Teen Pregnancy A Key Role for Health Care Providers Language: ... Battles: Teen Pregnancy Prevention Status Reports (PSRs): Teen Pregnancy FastStats: Teen Births Vital Signs – Preventing Teen Pregnancy [PODCAST – 1: ...

CDC Vital Signs-Preventing Stroke Deaths

Centers for Disease Control (CDC) Podcasts

This podcast is based on the September 2017 CDC Vital Signs report. Each year, more than 140,000 people die and many survivors face disability. Eighty percent of strokes are preventable. Learn the signs of stroke and how to prevent them.

Vital directions for mathematics education research

CERN Document Server

Leatham, Keith R

2013-01-01

In this book, experts discuss vital issues in mathematics education and what they see as viable directions for research in mathematics education to address them. Their recommendations take the form of overarching principles and ideas that cut across the field.

Vital Signs-Trucker Safety

Centers for Disease Control (CDC) Podcasts

2015-03-03

This podcast is based on the March 2015 CDC Vital Signs report. In 2012 in the United States, about 317,000 motor vehicle crashes involved a large truck. Twenty-six thousand truck drivers and their passengers were injured in these crashes, and about 700 died. Learn what can be done to help truck drivers stay safe.  Created: 3/3/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 3/3/2015.

The transport of irradiated fuel. An activity closely related to reprocessing

International Nuclear Information System (INIS)

Lenail, B.; Curtis, H.W.

1987-01-01

With a proven reprocessing capacity of 400 tonnes of uranium per year and the rapid expansion of this capacity, the need to feed the reprocessing plants at La Hague has become vital to ensure continuous and economic reprocessing. The programming of transports by the reprocessor and transporter to ensure a constant supply of fuel for reprocessing has therefore become increasingly important. These transports use the public roads and the railway system and the reprocessor and transporter must cooperate in maintaining the highest possible standards of safety. Safety must take priority over all other factors, including the economics of the operation

Development of strategic enterprise architecture design for the Ohio Department of Transportation.

Science.gov (United States)

2014-01-01

In order for the Ohio Department of Transportation (ODOT) to successfully carry out its mission, it is essential to : appropriately incorporate and utilize technology. Information management systems are vital to maintaining the states : transporta...

Linking air and water transport in intact soils to macro-porosity by combining laboratory measurements and X-ray Computed Tomography

DEFF Research Database (Denmark)

Katuwal, Sheela; Norgaard, Trine; Møldrup, Per

-porosity (R2 = 0.80 for air permeability: R2= 0.61 for 5% arrival time) and macro-porosity of the restricting layer (R2=0.83 for air permeability: R2= 0.71 for 5% arrival time) over air-filled porosity and all the correlations were positive. The high positive correlation these air and water transport...... functions with macro-porosity stressed the importance of continuity and tortuosity of pores in air, water and solute flow and transport through the soils. Negative correlations of air permeability, 5% arrival time of tracer and macro-porosity were obtained with bulk density whereas with other soil physical......With an objective to link the hydraulic properties of soil with the soil structural properties, air permeability and 5% arrival time of a conservative tracer was measured for large undisturbed soil columns from the same agricultural field. The same soil columns were scanned with a medical scanner...

Vital Signs-Preventing Prescription Drug Overdose

Centers for Disease Control (CDC) Podcasts

This podcast is based on the July 2014 CDC Vital Signs report. Every day, 46 people in the U.S. die from an overdose of prescription opioid painkillers. Learn what can be done to make painkiller prescribing safer and help prevent overdoses.

The Economic Vitality Formula of Success

Science.gov (United States)

Konopnicki, Patrick M.

2012-01-01

An economic vitality formula of success can be accomplished by creating partnerships between local career and technical education (CTE), and workforce development and economic development entities. Student industry certifications; dynamic partnerships; programs and projects focused on science, technology, engineering, and mathematics (STEM); and…

Vital Signs-Alcohol Poisoning Deaths

Centers for Disease Control (CDC) Podcasts

2015-01-06

This podcast is based on the January 2015 CDC Vital Signs report. In the United States, an average of six people die every day from alcohol poisoning. Learn what you can do to prevent binge drinking and alcohol poisoning.  Created: 1/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/6/2015.

SAR11 bacteria linked to ocean anoxia and nitrogen loss

DEFF Research Database (Denmark)

Tsementzi, Despina; Wu, Jieying; Deutsch, Samuel

2016-01-01

Bacteria of the SAR11 clade constitute up to one half of all microbial cells in the oxygen-rich surface ocean. SAR11 bacteria are also abundant in oxygen minimum zones (OMZs), where oxygen falls below detection and anaerobic microbes have vital roles in converting bioavailable nitrogen to N2 gas...... activity. These results link SAR11 to pathways of ocean nitrogen loss, redefining the ecological niche of Earth’s most abundant organismal group....

Externalities of the transport sector and the role of hydrogen in a sustainable transport vision

International Nuclear Information System (INIS)

Doll, Claus; Wietschel, Martin

2008-01-01

Transport systems perform vital societal functions, but in their present state cannot be considered 'sustainable'. One of the most controversially discussed long-term solutions to climate change and air emission externalities is the introduction of hydrogen as an energy fuel and fuel cell vehicles. In this paper, we integrate the two debates on the sustainability of today's transport systems and on the opportunities, threats and possible transition paths towards a 'hydrogen economy' in road transport. We focus our analysis on developed countries as well as the specific needs of the fast growing markets for car travel in the emerging economies. We conclude that the use of hydrogen can significantly reduce CO 2 emissions of the transport sector, even if taking into account tailpipe and upstream emissions as well as alternative technology developments. Moreover, local air pollutants can be reduced up to 80%. Possible negative impacts, including accident risks, nuclear waste or increased biomass demand, need to be benchmarked against these benefits. Thus, we highlight the need for integrated energy and transport policies and argue for more reflexive and inclusive societal debate about the impacts and beneficiaries of hydrogen transport technologies

Transport of radioactive wastes

International Nuclear Information System (INIS)

Stuller, C.

2003-01-01

In this article author describes the system of transport and processing of radioactive wastes from nuclear power of Slovenske elektrarne, plc. It is realized the assurance of transport of liquid and solid radioactive wastes to processing links from places of their formation, or of preliminary storage and consistent transports of treated radioactive wastes fixed in cement matrix of fibre-concrete container into Rebublic storage of radioactive wastes in Mochovce

CDC Vital Signs: Asthma in the US

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

CDC Vital Signs: HIV Care Saves Lives

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

Perceived discrimination, serotonin transporter linked polymorphic region status, and the development of conduct problems.

Science.gov (United States)

Brody, Gene H; Beach, Steven R H; Chen, Yi-Fu; Obasi, Ezemenari; Philibert, Robert A; Kogan, Steven M; Simons, Ronald L

2011-05-01

This study examined the prospective relations of adolescents' perceptions of discrimination and their genetic status with increases in conduct problems. Participants were 461 African American youths residing in rural Georgia (Wave 1 mean age = 15.5 years) who provided three waves of data and a saliva sample from which a polymorphism in the SCL6A4 (serotonin transporter [5-HTT]) gene polymorphism known as the 5-HTT linked promoter region (5-HTTLPR) was genotyped. Data analyses using growth curve modeling indicated that perceived discrimination was significantly related to the slope of conduct problems. As hypothesized, interactions between perceived discrimination and genetic status emerged for male but not female youths. Compared with those carrying two copies of the long allele variant of 5-HTTLPR, male youths carrying one or two copies of its short allele variant evinced higher rates of conduct problems over time when they perceived high levels of racial discrimination. These findings are consistent with resilience and differential susceptibility propositions stating that genes can both foster sensitivity to adverse events and confer protection from those events.

Relationships between vital rates and ecological traits in an avian community.

Science.gov (United States)

Bellier, Edwige; Kéry, Marc; Schaub, Michael

2018-03-30

Comparative studies about the relationships between vital rates and ecological traits at the community level are conspicuously lacking for most taxa because estimating vital rates requires detailed demographic data. Identifying relationships between vital rates and ecological traits could help to better understand ecological and evolutionary demographic mechanisms that lead to interspecific differences in vital rates. We use novel dynamic N-mixture models for counts to achieve this for a whole avian community comprising 53 passerine species, while simultaneously accounting for density dependence and environmental stochasticity in recruitment and survival and, importantly, correcting our inferences for imperfect detection. Demographic stochasticity is taken into account in the form of the binomial and Poisson distributions describing survival events and number of recruits. We then explore relationships between estimated demographic parameters (i.e., vital rates) and ecological traits related to migration patterns, diet, habitat and nesting location of each species. The relative importance of recruitment and adult survival as contributors to population growth varied greatly among species, and interspecific differences in vital rates partly reflected differences in ecological traits. Migratory mode was associated with interspecific differences in population growth and density dependence. Resident species had higher population growth rates than long- and short-distance migrants. We found no relationships between diet and population growth rate. Habitat differences were associated with different growth rates: alpine, wetland and farmland species had lower population growth rates than forest species. Differences in population growth rates among nesting locations showed that breeding habitat is essential for population dynamics. Our study reveals relationships between ecological traits and contributions of vital rates to population growth and suggests ways in which

Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis.

Science.gov (United States)

Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

2016-01-01

Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern "vitality forms". Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing.

Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis

Science.gov (United States)

Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

2016-01-01

Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern “vitality forms”. Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing. PMID:27375461

Validating emergency department vital signs using a data quality engine for data warehouse.

Science.gov (United States)

Genes, N; Chandra, D; Ellis, S; Baumlin, K

2013-01-01

Vital signs in our emergency department information system were entered into free-text fields for heart rate, respiratory rate, blood pressure, temperature and oxygen saturation. We sought to convert these text entries into a more useful form, for research and QA purposes, upon entry into a data warehouse. We derived a series of rules and assigned quality scores to the transformed values, conforming to physiologic parameters for vital signs across the age range and spectrum of illness seen in the emergency department. Validating these entries revealed that 98% of free-text data had perfect quality scores, conforming to established vital sign parameters. Average vital signs varied as expected by age. Degradations in quality scores were most commonly attributed logging temperature in Fahrenheit instead of Celsius; vital signs with this error could still be transformed for use. Errors occurred more frequently during periods of high triage, though error rates did not correlate with triage volume. In developing a method for importing free-text vital sign data from our emergency department information system, we now have a data warehouse with a broad array of quality-checked vital signs, permitting analysis and correlation with demographics and outcomes.

CDC Vital Signs-Heroin Epidemic

Centers for Disease Control (CDC) Podcasts

2015-07-07

This podcast is based on the July 2015 CDC Vital Signs report. Heroin use and heroin-related overdose deaths are increasing. Most people are using it with other drugs, especially prescription opioid painkillers. Learn what can be done to prevent and treat the problem.  Created: 7/7/2015 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 7/7/2015.

Connecting HRM and Change Management: The Importance of Proactivity and Vitality

NARCIS (Netherlands)

L.G. Tummers (Lars); P.M. Kruyen; D. Vijverberg (Dominique); T. Voesenek (Tessa)

2014-01-01

markdownabstract__Abstract__ __Purpose__: Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it

CDC Vital Signs-Cancer and Obesity

Centers for Disease Control (CDC) Podcasts

This podcast is based on the October 2017 CDC Vital Signs report. Obesity is a leading cancer risk factor. Unfortunately, two out of three U.S. adults weigh more than recommended. Find out what can be done to help people get to and keep a healthy weight.

Structure of Stenotrophomonas maltophilia FeoA complexed with zinc: a unique prokaryotic SH3-domain protein that possibly acts as a bacterial ferrous iron-transport activating factor

International Nuclear Information System (INIS)

Su, Yi-Che; Chin, Ko-Hsin; Hung, Hui-Chih; Shen, Gwan-Han; Wang, Andrew H.-J.; Chou, Shan-Ho

2010-01-01

The crystal structure of FeoA from Stenotrophomonas maltophilia has been determined to a resolution of 1.7 Å using an Se single-wavelength anomalous dispersion (Se-SAD) approach and revealed a unique dimer cross-linked by two zinc ions and six chloride ions. Iron is vital to the majority of prokaryotes, with ferrous iron believed to be the preferred form for iron uptake owing to its much better solubility. The major route for bacterial ferrous iron uptake is found to be via an Feo (ferrous iron-transport) system comprising the three proteins FeoA, FeoB and FeoC. Although the structure and function of FeoB have received much attention recently, the roles played by FeoA and FeoC have been little investigated to date. Here, the tertiary structure of FeoA from Stenotrophomonas maltophilia (Sm), a vital opportunistic pathogen in immunodepressed hosts, is reported. The crystal structure of SmFeoA has been determined to a resolution of 1.7 Å using an Se single-wavelength anomalous dispersion (Se-SAD) approach. Although SmFeoA bears low sequence identity to eukaryotic proteins, its structure is found to adopt a eukaryotic SH3-domain-like fold. It also bears weak similarity to the C-terminal SH3 domain of bacterial DtxR (diphtheria toxin regulator), with some unique characteristics. Intriguingly, SmFeoA is found to adopt a unique dimer cross-linked by two zinc ions and six anions (chloride ions). Since FeoB has been found to contain a G-protein-like domain with low GTPase activity, FeoA may interact with FeoB through the SH3–G-protein domain interaction to act as a ferrous iron-transport activating factor

Identification of Vital Areas at Nuclear Facilities. Technical Guidance

International Nuclear Information System (INIS)

2012-01-01

nuclear installations against sabotage are contained in IAEA Nuclear Security Series No. 13, Nuclear Security Recommendations on Physical Protection of Nuclear Material and Nuclear Facilities (INFCIRC/225/Revision 5). After the attacks of 11 September 2001, the perception of the potential terrorist threat to nuclear installations changed significantly, and the IAEA initiated an effort to develop a series of guidance publications on the security of nuclear and radioactive material and facilities. This publication presents a structured approach to identifying the areas that contain equipment, systems, and components to be protected against sabotage. It specifically provides detailed guidance with regard to the identification of vital areas, that is, the areas to be protected in high consequence facilities. However, the process described is applicable to the identification of areas that should be protected at any nuclear facility. The method builds upon safety analyses to develop sabotage logic models for sabotage scenarios that could cause unacceptable radiological consequences. The sabotage actions represented in the logic models are linked to the areas from which they can be accomplished. The logic models are then analysed to determine areas that should be protected to prevent these unacceptable radiological consequences.

Distinct regimes of elastic response and deformation modes of cross-linked cytoskeletal and semiflexible polymer networks

NARCIS (Netherlands)

Head, D.A.; Levine, A.M.; Mac Kintosh, F.C.

2003-01-01

Semiflexible polymers such as filamentous actin (F-actin) play a vital role in the mechanical behavior of cells, yet the basic properties of cross-linked F-actin networks remain poorly understood. To address this issue, we have performed numerical studies of the linear response of homogeneous and

The Vitality of Disease

DEFF Research Database (Denmark)

Wahlberg, Ayo

2017-01-01

of what we might be conceptualised as the vitality of disease. Medical interventions are increasingly as much about improving (quality of) life as they are about saving and prolonging life. As a consequence, morbid living has come to be disciplined, for example, in patient schools aimed at teaching...... patients to learn how to live with their disease, through rating scales used to measure treatment effect on the ‘quality of life’ of patients in clinical trials and through disease-specific ‘Living with’ guides aimed at patients and carers....

EDF energy generation UK transport of irradiated fuel

Energy Technology Data Exchange (ETDEWEB)

James, R. [EDF Energy, London, (United Kingdom)

2015-07-01

This paper give an overview of irradiated fuel transport in the UK. It describes the design of irradiated fuel flask used by EDF Energy; operational experience and good practices learnt from over 50 years of irradiated fuel transport. The AGRs can store approximately 9 months generation of spent fuel, hence the ability to transport irradiated fuel is vital. Movements are by road to the nearest railhead, typically less than 2 miles and then by rail to Sellafield, up to 400 miles, for reprocessing or long term storage. Road and rail vehicles are covered. To date in the UK: over 30,000 Magnox flask journeys and over 15,000 AGR A2 flask journeys have been carried out.

Connecting HRM and change management: the importance of proactivity and vitality

NARCIS (Netherlands)

Tummers, L.G.; Kruyen, P.M.; Vijverberg, D.M.; Voesenek, T.J.

2015-01-01

- Purpose – Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it is still unclear how

Connecting HRM and Change Management: The Importance of Proactivity and Vitality

NARCIS (Netherlands)

L.G. Tummers (Lars); P.M. Kruyen; D. Vijverberg (Dominique); T. Voesenek (Tessa)

2015-01-01

textabstractPurpose. Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it is still unclear how

Connecting HRM and Change Management: The Importance of Proactivity and Vitality

NARCIS (Netherlands)

Tummers, L.G.; Kruyen, P.M.; Vijverberg, D.; Voesenek, T.

2015-01-01

Purpose. Organizations are continuously under pressure to adapt to changing circumstances. Job proactivity and vitality are important in changing environments. For instance, vital employees can better deal with change because they possess more energy. However, it is still unclear how organizations

Optical sensor for measuring American Lobster vitality

International Nuclear Information System (INIS)

Tomassetti, Brian R. A.; Vetelino, John F.

2011-01-01

The vitality of the American Lobster (Homarus americanus) is correlated to the total hemolymph protein (THP) in lobster hemolymph (blood). The standard technique for determining lobster vitality is to draw blood from a lobster and measure THP with a refractometer. This technique is invasive and endangers the lobster's health since blood must be drawn from the lobster. In the present work an optical sensor is developed to measure a lobster's vitality in vivo. It is comprised of a broadband light source, a monochromator, a fiber optic reflection probe, a spectrometer and a computer. This sensor measures protein concentrations by exciting a lobster with 280 nm and 334 nm wavelength light sources and measuring the corresponding absorbance peaks for THP and the fluorescence peak for hemocyanin (Hc), the majority protein in hemolymph. In this work several lobsters are tested. For each lobster, absorbance and fluorescence peaks are measured using the sensor and compared to protein concentrations measured using a refractometer. It is found that the shell thickness and muscle density, which correspond directly to protein concentration and the molting stage of the lobster have a significant effect on the absorbance and fluorescence measurements. It is also found that within specific molting stages, such as pre-molt and post-molt, protein concentration measured with a refractometer correlates linearly to absorbance and fluorescence measurements with the optical sensor.

Optical Sensor for Measuring American Lobster Vitality

Science.gov (United States)

Tomassetti, Brian R. A.; Vetelino, John F.

2011-06-01

The vitality of the American Lobster (Homarus americanus) is correlated to the total hemolymph protein (THP) in lobster hemolymph (blood). The standard technique for determining lobster vitality is to draw blood from a lobster and measure THP with a refractometer. This technique is invasive and endangers the lobster's health since blood must be drawn from the lobster. In the present work an optical sensor is developed to measure a lobster's vitality in vivo. It is comprised of a broadband light source, a monochromator, a fiber optic reflection probe, a spectrometer and a computer. This sensor measures protein concentrations by exciting a lobster with 280 nm and 334 nm wavelength light sources and measuring the corresponding absorbance peaks for THP and the fluorescence peak for hemocyanin (Hc), the majority protein in hemolymph. In this work several lobsters are tested. For each lobster, absorbance and fluorescence peaks are measured using the sensor and compared to protein concentrations measured using a refractometer. It is found that the shell thickness and muscle density, which correspond directly to protein concentration and the molting stage of the lobster have a significant effect on the absorbance and fluorescence measurements. It is also found that within specific molting stages, such as pre-molt and post-molt, protein concentration measured with a refractometer correlates linearly to absorbance and fluorescence measurements with the optical sensor.

CDC Vital Signs-African American Health

Centers for Disease Control (CDC) Podcasts

This podcast is based on the May 2017 CDC Vital Signs report. The life expectancy of African Americans has improved, but it's still an average of four years less than whites. Learn what can be done so all Americans can have the opportunity to pursue a healthy lifestyle.

The naphthoquinones, vitamin K3 and its structural analog plumbagin, are substrates of the multidrug resistance-linked ABC drug transporter ABCG2

OpenAIRE

Shukla, Suneet; Wu, Chung-Pu; Nandigama, Krishnamachary; Ambudkar, Suresh V.

2007-01-01

Vitamin K3 (Menadione; 2-methyl-1,4-naphthoquinone) is a structural precursor of vitamins K1 and K2 which are essential for blood clotting. The naturally occurring structural analog of this vitamin, plumbagin (5-hydroxy-menadione), is known to modulate cellular proliferation, apoptosis, carcinogenesis, and radioresistance. We, here, report that both vitamin K3 and plumbagin are substrates of the multidrug resistance-linked ATP binding cassette (ABC) drug transporter, ABCG2. Vitamin K3 and plu...

In vitro cross-linking of elastin peptides and molecular characterization of the resultant biomaterials

DEFF Research Database (Denmark)

Heinz, Andrea; Ruttkies, Christoph K H; Jahreis, Günther

2013-01-01

-link desmosine or isodesmosine was unexpected, however, could be confirmed by tandem mass spectrometry and molecular dynamics simulations. CONCLUSIONS: The study demonstrated that it is possible to produce biopolymers containing polyfunctional cross-links characteristic of mature elastin from small elastin......BACKGROUND: Elastin is a vital protein and the major component of elastic fibers which provides resilience to many vertebrate tissues. Elastin's structure and function are influenced by extensive cross-linking, however, the cross-linking pattern is still unknown. METHODS: Small peptides containing...... and the insoluble polymers, after digestion with pancreatic elastase or trypsin, were furthermore comprehensively characterized on the molecular level using MALDI-TOF/TOF mass spectrometry. RESULTS: MS(2) data was used to develop the software PolyLinX, which is able to sequence not only linear and bifunctionally...

Paradoxes in networks with zero emission links: implications for telecommunications versus transportation

Energy Technology Data Exchange (ETDEWEB)

Nagurney, A. [University of Massachusetts, Amherst, MA (United States). Isenberg School of Management; June Dong [State University of New York, Oswego, NY (United States). School of Business

2001-07-01

In this paper, we consider networks in which a link is characterized by zero emissions as is typical of networks in which certain links correspond to telecommunication links. We identify three new and distinct paradoxical phenomena that can occur in such networks, which demonstrate that so-called improvements to the network may result in increases in total emissions generated. In particular, we illustrate, through specific examples, the following: (1) the addition of a link with zero emissions may result in an increase in total emissions with no change in travel demand; (2) the total emissions on a network with a zero emission link may increase with a decrease in travel demand; and (3) the addition of a path connecting an origin/destination (O/D) pair and consisting solely of a zero emission link may result in an increase in total emissions. We then propose an emission pricing policy which guarantees that such paradoxes do not occur. The pricing policy is shown to be equivalent to a particular weighting mechanism associated with the criterion of emission generation provided that the users are now multicriteria decision-makers who seek to minimize both the cost of their route choices as well as the emissions that they generate. (author)

33 CFR 157.435 - Vital systems surveys.

Science.gov (United States)

2010-07-01

...) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain Tank Vessels Without Double Hulls Carrying Petroleum Oils § 157.435 Vital...

Transportation of hazardous and nuclear materials

International Nuclear Information System (INIS)

Boryczka, M.; Shaver, D.

1989-01-01

Transportation of hazardous and radioactive materials is a vital part of the nation's economy. In recent years public concern over the relative safety of transporting hazardous materials has risen sharply. The United States has a long history of transporting hazardous and radioactive material; rocket propellants, commercial spent fuel, low-level and high-level radioactive waste has been shipped for years. While the track record for shipping these materials is excellent, the knowledge that hazardous materials are passing through communities raises the ire of citizens and local governments. Public outcry over shipments containing hazardous cargo has been especially prominent when shippers have attempted to transport rocket propellants or spent nuclear fuel. Studies of recent shipments have provided insight into the difficulties of shipping in a politically charged environment, the major issues of concern to citizens, and some of the more successful methods of dealing with public concerns. This paper focuses on lessons learned from these studies which include interviews with shippers, carriers, and regulators

The utility industry's perspective on OCRWM's plans for developing the system for transporting spent fuel under the Nuclear Waste Policy Act

International Nuclear Information System (INIS)

Brodnick, D.A.

1988-01-01

The electric utility industry has a vital interest in the transport program to be developed by the Department of Energy's Office of Civilian Radioactive Waste Management under the Nuclear Waste Policy Act. The industry's interest stems in part from the fact that the DOE's transportation program is financed by the Nuclear Waste Fund which is made up of ratepayer funds. However, the industry is also vitally interested in the DOE's transportation program because it could impact the ongoing transportation operations of all nuclear utilities, and, perhaps most importantly, without the utility industry's input, DOE is not able to develop an optimal transportation program. The NWPA contemplates that the DOE conducts its transportation program in accordance with the existing federal and state regulatory structure. DOE has significant discretion, however, in creating and implementing the business, operational and institutional aspects of its NWPA transportation program. The utility industry intends to ensure that the DOE meets the challenge to develop a safe, efficient and economically sound program to transport spent fuel and high-level waste to the appropriate federal facilities

Boulders, biology and buildings: Why weathering is vital to geomorphology (Ralph Alger Bagnold Medal Lecture)

Science.gov (United States)

Viles, Heather A.

2015-04-01

Weathering is vital to geomorphology in three main senses. First, it is vital in the sense of being a fundamental and near-ubiquitous earth surface process without which landscapes would not develop, and which also provides a key link between geomorphology and the broader Earth system. Second, weathering is vital in the sense that, as it is heavily influenced by biotic processes, it demonstrates the importance of life to geomorphology and vice versa. In particular, weathering illustrates the many cross-linkages between microbial ecosystems and geomorphology. Finally, it is vital in the sense that weathering provides an important practical application of geomorphological knowledge. Geomorphologists in recent years have contributed much in terms of improving understanding the deterioration of rocks, stone and other materials in heritage sites and the built environment. This knowledge has also had direct implications for heritage conservation. This lecture reviews recent research on each of these three themes and on their linkages, and sets an integrated research agenda for the future. Weathering as a key process underpinning geomorphology and Earth system science has been the subject of much recent conceptual and empirical research. In particular, conceptual research advances have involved improving conceptualisation of scale issues and process synergies, and understanding weathering in terms of non-linear dynamical systems. Empirical advances have included the development of larger datasets on weathering rates, and the application of a wide range of non-destructive and remote sensing techniques to quantify weathering morphologies on boulder and rock surfaces. In recent years, understanding of the complex linkages between ecology and geomorphology (sometimes called biogeomorphology) has advanced particularly strongly in terms of weathering. For example, the influences of disturbance on biota and weathering have been conceptualised and investigated empirically in a

An Automatic Matcher and Linker for Transportation Datasets

Directory of Open Access Journals (Sweden)

Ali Masri

2017-01-01

Full Text Available Multimodality requires the integration of heterogeneous transportation data to construct a broad view of the transportation network. Many new transportation services are emerging while being isolated from previously-existing networks. This leads them to publish their data sources to the web, according to linked data principles, in order to gain visibility. Our interest is to use these data to construct an extended transportation network that links these new services to existing ones. The main problems we tackle in this article fall in the categories of automatic schema matching and data interlinking. We propose an approach that uses web services as mediators to help in automatically detecting geospatial properties and mapping them between two different schemas. On the other hand, we propose a new interlinking approach that enables the user to define rich semantic links between datasets in a flexible and customizable way.

Vital Signs-Preventing Teen Pregnancy

Centers for Disease Control (CDC) Podcasts

2015-04-07

This podcast is based on the April 2015 CDC Vital Signs report. Teen births in the U.S. have declined, but still, more than 273,000 infants were born to teens ages 15 to 19 in 2013. Learn about the most effective types of birth control.  Created: 4/7/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/7/2015.

CDC Vital Signs-Heart Age

Centers for Disease Control (CDC) Podcasts

This podcast is based on the September 2015 CDC Vital Signs report. Your heart age is the age of your heart and blood vessels as a result of your risk factors for heart attack and stroke. If you smoke or have high blood pressure, your heart age will be much higher than your actual age. Learn what you can do to lower your heart age and keep it low.

CDC Vital Signs-Hispanic Health

Centers for Disease Control (CDC) Podcasts

This podcast is based on the May 2015 CDC Vital Signs report. About one in six people living in the U.S. are Hispanic. The two leading causes of death in this group are heart disease and cancer, accounting for two out of five deaths. Unfortunately, many Hispanics face considerable barriers to getting high quality health care, including language and low income. Learn what can be done to reduce the barriers.

The transport of radioactive materials - Future challenges

International Nuclear Information System (INIS)

Wilkinson, W.L.

2008-01-01

The International Atomic Energy Agency (IAEA) Regulations for the Safe Transport of Radioactive Materials, TS-R-1, set the standards for the packages used in the transport of radioactive materials under both normal and accident conditions. Transport organisations are also required to implement Radiation Protection Programmes to control radiation dose exposure to both workers and the public. The industry has now operated under this regulatory regime safely and efficiently for nearly 50 years. It is vital that this record be maintained in the future when the demands on the transport industry are increasing. Nuclear power is being called upon more and more to satisfy the world's growing need for sustainable, clean and affordable electricity and there will be a corresponding demand for nuclear fuel cycle services. There will also be a growing need for other radioactive materials, notably large sources such as Cobalt 60 sources for a range of important medical and industrial uses, as well as radio-pharmaceuticals. A reliable transport infrastructure is essential to support all these industry sectors and the challenge will be to ensure that this can be maintained safely and securely in a changing world where public and political concerns are increasing. This paper will discuss the main issues which need to be addressed. The demand for uranium has led to increased exploration and the development of mines in new locations far removed from the demand centres. This inevitably leads to more transport, sometimes from areas potentially lacking in transport infrastructure, service providers, and experience. The demand for sources for medical applications will also increase, particularly from the rapidly developing regions and this will also involve new transport routes and increased traffic. This raises a variety of issues concerning the ability of the transport infrastructure to meet the future challenge, particularly in an environment where there already exists reluctance on

The role of physical activity in pre-service teachers’ subjective vitality

Directory of Open Access Journals (Sweden)

Abdullah Bora Özkara

2017-06-01

Full Text Available Background: In the present study, subjective vitality considered to be one of the contributions provided by participation in physical activity is examined on a sample of pre-service teachers. When teachers who are important part of education system are healthy and fit, it will help to build future generations. Materials: The research was conducted in the city of Trabzon, located in the northeastern region of Turkey. The sample of the study is composed of 328 last grade pre-service teachers (133 women, 195 men, age: 23.14 ± 2.62 studying at Karadeniz Technical University in the academic year of 2015-2016. Data was collected through Childhood and Adolescence Physical Activity Levels Questionnaire, Subjective Vitality Scale, and a personal information form asking for information about gender, doing sports as a certified sportsman/woman and department. Results: The research results yielded a significant difference between subjective vitality levels of those who do sports as a certified sportsman/woman and those who do not, and between pre-service teachers of physical education and those of other departments (p<0,01. There was also a positive and low-level significant relationship between subjective vitality and physical activity experiences of pre-service teachers (r= .23; p<0.01. However, subjective vitality did not differ significantly by gender. Conclusions: The research results seem to support other studies that reveal social and psychological contributions provided by participation in physical activity. Therefore, participation in physical activity seems to have positive effects on the subjective vitality of pre-service teachers.

Assessment of ground transportation stress in juvenile Kemp's ridley sea turtles (Lepidochelys kempii).

Science.gov (United States)

Hunt, Kathleen E; Innis, Charles J; Kennedy, Adam E; McNally, Kerry L; Davis, Deborah G; Burgess, Elizabeth A; Merigo, Constance

2016-01-01

Sea turtle rehabilitation centres frequently transport sea turtles for long distances to move animals between centres or to release them at beaches, yet there is little information on the possible effects of transportation-related stress ('transport stress') on sea turtles. To assess whether transport stress is a clinically relevant concern for endangered Kemp's ridley sea turtles (Lepidochelys kempii), we obtained pre-transport and post-transport plasma samples from 26 juvenile Kemp's ridley sea turtles that were transported for 13 h (n = 15 turtles) or 26 h (n = 11 turtles) by truck for release at beaches. To control for effects of handling, food restriction and time of day, the same turtles were also studied on 'control days' 2 weeks prior to transport, i.e. with two samples taken to mimic pre-transport and post-transport timing, but without transportation. Blood samples were analysed for nine clinical health measures (pH, pCO2, pO2, HCO3, sodium, potassium, ionized calcium, lactate and haematocrit) and four 'stress-associated' parameters (corticosterone, glucose, white blood cell count and heterophil-to-lymphocyte ratio). Vital signs (heart rate, respiratory rate and cloacal temperature) were also monitored. Corticosterone and glucose showed pronounced elevations due specifically to transportation; for corticosterone, this elevation was significant only for the longer transport duration, whereas glucose increased significantly after both transport durations. However, clinical health measures and vital signs showed minimal or no changes in response to any sampling event (with or without transport), and all turtles appeared to be in good clinical health after both transport durations. Thus, transportation elicits a mild, but detectable, adrenal stress response that is more pronounced during longer durations of transport; nonetheless, Kemp's ridley sea turtles can tolerate ground transportation of up to 26 h in good health. These results are likely

Littoral transport studies along west coast of India - A reivew

Digital Repository Service at National Institute of Oceanography (India)

Kunte, P.D.; Wagle, B.G.; Sugimori, Y.

an important role in deciding the areas of coastal erosion and accretion, in shaping and orienting coastal landforms and finally in the evolution of the coast. Hence, in the analysis of coastal erosion-accretion problem, for the development of harbour... and construction of coastal structures, the direction, amount and behaviour of long-term average shore drift is of vital importance. Littoral transport is defined as the movement of sediments in the near shore zone by waves and currents. Littoral transport...

CDC Vital Signs: Preventing Repeat Teen Births

Science.gov (United States)

... control after they have given birth. Although teen birth rates have been falling for the last two decades, ... effective forms of birth control. SOURCE: National Vital Statistics System, teens, ages 15–19, 2010 Larger image ...

CDC Vital Signs-Hospital Actions Affect Breastfeeding

Centers for Disease Control (CDC) Podcasts

This podcast is based on the October 2015 CDC Vital Signs report. Hospitals can implement the Ten Steps to Successful Breastfeeding to be designated as "Baby-Friendly" and support more moms in a decision to breastfeed.

Using sediment transport and river restoration to link research and education, and promote K-12 female involvement in STEM fields

Science.gov (United States)

Yager, E. M.; Bradley-Eitel, K.

2011-12-01

The focus of this CAREER award is to better understand and predict the mechanics of sediment transport, to link research and education through courses and shared field sites, and to increase female interest in STEM fields. To accomplish the education component of this proposal we have focused on the following three activities: 1) a Keystone course on the scientific method, 2) a Women Outside with Science (WOWS) camp and 3) a permanent field site for research and education on river processes. In the Keystone Course, students investigated the impact of roughness addition, in sediment-starved river reaches (e.g. downstream of dams), on the retention of gravel used for spawning. They developed research questions and hypotheses, designed and conducted a set of scaled laboratory flume experiments, analyzed their data and wrote a draft manuscript of their results. Student feedback was overwhelmingly positive on the merits of this course, which included hands-on learning of the following: basic sediment transport and fluvial geomorphology, applied statistics, laboratory methods, and scientific writing skills. Students sometimes struggled when flume experiments did not progress as planned, and in the analysis and interpretation of complex data. Some of the students in the course have reanalyzed data, conducted additional experiments and are currently rewriting the manuscript for submission to a peer-reviewed journal. Such a course fundamentally links research and teaching, and provides an introduction to research for advanced undergraduates or beginning graduate students. We have also run one summer WOWS camp, which was a ten day camping and inquiry based research experience for 20 female junior-high and high-school students. The girls studied climate change and water related issues, worked on a restoration project on the Little Salmon River, met with a fish biologist and did fish habitat surveys and studied water quality along the North Fork of the Payette River while on a

ED Triage Process Improvement: Timely Vital Signs for Less Acute Patients.

Science.gov (United States)

Falconer, Stella S; Karuppan, Corinne M; Kiehne, Emily; Rama, Shravan

2018-06-13

Vital signs can result in an upgrade of patients' Emergency Severity Index (ESI) levels. It is therefore preferable to obtain vital signs early in the triage process, particularly for ESI level 3 patients. Emergency departments have an opportunity to redesign triage processes to meet required protocols while enhancing the quality and experience of care. We performed process analyses to redesign the door-to-vital signs process. We also developed spaghetti diagrams to reconfigure the patient arrival area. The door-to-vital signs time was reduced from 43.1 minutes to 6.44 minutes. Both patients and triage staff seemed more satisfied with the new process. The patient arrival area was less congested and more welcoming. Performing activities in parallel reduces flow time with no additional resources. Staff involvement in process planning, redesign, and control ensures engagement and early buy-in. One should anticipate how changes to one process might affect other processes. Copyright © 2018. Published by Elsevier Inc.

Longitudinal modeling to predict vital capacity in amyotrophic lateral sclerosis.

Science.gov (United States)

Jahandideh, Samad; Taylor, Albert A; Beaulieu, Danielle; Keymer, Mike; Meng, Lisa; Bian, Amy; Atassi, Nazem; Andrews, Jinsy; Ennist, David L

2018-05-01

Death in amyotrophic lateral sclerosis (ALS) patients is related to respiratory failure, which is assessed in clinical settings by measuring vital capacity. We developed ALS-VC, a modeling tool for longitudinal prediction of vital capacity in ALS patients. A gradient boosting machine (GBM) model was trained using the PRO-ACT (Pooled Resource Open-access ALS Clinical Trials) database of over 10,000 ALS patient records. We hypothesized that a reliable vital capacity predictive model could be developed using PRO-ACT. The model was used to compare FVC predictions with a 30-day run-in period to predictions made from just baseline. The internal root mean square deviations (RMSD) of the run-in and baseline models were 0.534 and 0.539, respectively, across the 7L FVC range captured in PRO-ACT. The RMSDs of the run-in and baseline models using an unrelated, contemporary external validation dataset (0.553 and 0.538, respectively) were comparable to the internal validation. The model was shown to have similar accuracy for predicting SVC (RMSD = 0.562). The most important features for both run-in and baseline models were "Baseline forced vital capacity" and "Days since baseline." We developed ALS-VC, a GBM model trained with the PRO-ACT ALS dataset that provides vital capacity predictions generalizable to external datasets. The ALS-VC model could be helpful in advising and counseling patients, and, in clinical trials, it could be used to generate virtual control arms against which observed outcomes could be compared, or used to stratify patients into slowly, average, and rapidly progressing subgroups.

Sand transport, erosion and granular electrification

DEFF Research Database (Denmark)

Merrison, J.P.

2012-01-01

is expanding our current understanding and outline the areas of advancement needed in the future. Presentation is made of current models for wind driven detachment/entrainment and the transport rates of sand and dust, including the effects of contact induced grain electrification. This ubiquitous phenomenon...... can affect grain transport through the generation of intense electric fields and processes of electrostatic assembly. Importantly the transport of sand is characterized by saltation, which is known to be an active process for erosion and therefore a source for dust and sand formation. Using novel...... erosion simulation techniques the link between grain transport rates and erosion rates has been quantified. Furthermore this can be linked to production rates for dust and has been associated with chemical and mineral alteration through a process of mechanical activation of fractured surfaces. This work...

Vital Signs – Childhood Obesity

Centers for Disease Control (CDC) Podcasts

This podcast is based on the August 2013 CDC Vital Signs report. The rate of obesity among low-income preschoolers has declined, but one in eight is still obese. This program briefly discusses what can be done.

CDC Vital Signs-Preventing Melanoma

Centers for Disease Control (CDC) Podcasts

2015-06-02

This podcast is based on the June 2015 CDC Vital Signs report. Skin cancer is the most common form of cancer in the U.S. In 2011, there were more than 65,000 cases of melanoma, the most deadly form of skin cancer. Learn how everyone can help prevent skin cancer.  Created: 6/2/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 6/2/2015.

Vital Signs - Child Passenger Safety

Centers for Disease Control (CDC) Podcasts

2014-02-04

This podcast is based on the February 2014 CDC Vital Signs report. Over the past 10 years, more than 9,000 children 12 and under died in motor vehicle crashes, and a third who died in 2011 weren't buckled up. Buckling up is the best way to reduce injuries and save lives.  Created: 2/4/2014 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 2/4/2014.

Structural model of a putrescine-cadaverine permease from Trypanosoma cruzi predicts residues vital for transport and ligand binding

NARCIS (Netherlands)

Soysa, R.; Venselaar, H.; Poston, J.; Ullman, B.; Hasne, M.P.

2013-01-01

The TcPOT1.1 gene from Trypanosoma cruzi encodes a high affinity putrescine-cadaverine transporter belonging to the APC (amino acid/polyamine/organocation) transporter superfamily. No experimental three-dimensional structure exists for any eukaryotic member of the APC family, and thus the structural

47 CFR 69.125 - Dedicated signalling transport.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Dedicated signalling transport. 69.125 Section... (CONTINUED) ACCESS CHARGES Computation of Charges § 69.125 Dedicated signalling transport. (a) Dedicated signalling transport shall consist of two elements, a signalling link charge and a signalling transfer point...

Energy brands lack vitality

International Nuclear Information System (INIS)

Godri, S.; Wilders, E.

2004-01-01

The three Dutch energy companies (Nuon, Essent and Eneco Energie) have relatively little brand strength. The brands are not perceived to be sufficiently different from one another and are not valued by consumers. With liberalisation imminent, this is hardly a strong starting point. How can you win over consumers if it is not clear what is on offer? In the business market, decision-makers are better placed to distinguish between brands. However, the brands lack vitality in this sector of the market too. The only consolation is that the situation is by no means exclusive to the Netherlands [nl

Atmospheric Transport and Mixing linked to Rossby Wave Breaking in GFDL Dynamical Core

Science.gov (United States)

Liu, C.; Barnes, E. A.

2015-12-01

Atmospheric transport and mixing plays an important role in the global energy balance and the distribution of health-related chemical constituents. Previous studies suggest a close linkage between large-scale transport and Rossby wave breaking (RWB). In this work, we use the GFDL spectral dynamical core to investigate this relationship and study the response of RWB-related transport in different climate scenarios. In a standard control run, we quantify the contribution of RWB to the total transport and mixing of an idealized tracer. In addition, we divide the contribution further into the two types of RWB - anticyclonic wave breaking (AWB) and cyclonic wave breaking (CWB) -- and contrast their efficiency at transport and mixing. Our results are compared to a previous study in which the transport ability of the two types of RWB is studied for individual baroclinic wave life-cycles. In a series of sensitivity runs, we study the response of RWB-related transport and mixing to various states of the jet streams. The responses of the mean strength, frequency, and the efficiency of RWB-related transport are documented and the implications for the transport and mixing in a warmer climate are discussed.

CDC Vital Signs-Communication Can Save Lives

Centers for Disease Control (CDC) Podcasts

This podcast is based on the August 2015 CDC Vital Signs report. Antibiotic-resistant germs cause at least 23,000 deaths each year. Learn how public health authorities and health care facilities can work together to save lives.

Vital Signs-Motor Vehicle Crash Injuries

Centers for Disease Control (CDC) Podcasts

2014-10-07

This podcast is based on the October 2014 CDC Vital Signs report. Motor vehicle crashes are costly and preventable. Learn what can be done to help prevent motor vehicle injuries.  Created: 10/7/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 10/7/2014.

Recent innovations in last mile deliveries. In : Non-technological Innovations for Sustainable Transport: Four Transport Case Studies

OpenAIRE

MORGANTI, Eléonora; DABLANC, Laetitia

2014-01-01

In cities and metropolitan areas, last mile deliveries are a key factor contributing to local economic vitality, urban life quality and attractiveness of urban communities. However, the freight transport sector is responsible for negative impacts, mainly with regards to congestion, CO2 emissions and air and noise pollution. In order to improve efficiency and reduce adverse impacts, private companies as well as city planners and policy makers have designed initiatives to promote urban logistic...

An Assessment of LAC's Vital Statistics System : The Foundation of Maternal and Infant Mortality Monitoring

OpenAIRE

Danel, Isabella; Bortman, Marcelo

2008-01-01

Vital records, the registration of births, deaths, marriages and divorces, and the vital statistics derived from these records serve two important purposes. Firstly, vital records are legal documents, but the focus of this review, is the role of vital records to create demographic and epidemiological statistics that are used in monitoring trends and developing health policies and programs....

Vital and dispensable roles of Plasmodium multidrug resistance transporters during blood- and mosquito-stage development

NARCIS (Netherlands)

Rijpma, S.R.; Velden, M. van der; Annoura, T.; Matz, J.M.; Kenthirapalan, S.; Kooij, T.W.; Matuschewski, K.; Gemert, G.J.A. van; Vegte-Bolmer, M.G. van de; Siebelink-Stoter, R.; Graumans, W.; Ramesar, J.; Klop, O.; Russel, F.G.; Sauerwein, R.W.; Janse, C.J.; Franke-Fayard, B.M.; Koenderink, J.B.

2016-01-01

Multidrug resistance (MDR) proteins belong to the B subfamily of the ATP Binding Cassette (ABC) transporters, which export a wide range of compounds including pharmaceuticals. In this study, we used reverse genetics to study the role of all seven Plasmodium MDR proteins during the life cycle of

Vital Signs-Cervical Cancer is Preventable!

Centers for Disease Control (CDC) Podcasts

This podcast is based on the November 2014 CDC Vital Signs report. Every visit to a doctor or nurse is an opportunity to prevent cervical cancer. Women can get a Pap test and HPV test to help prevent cervical cancer and adolescent boys and girls can get the HPV vaccination series to help prevent cervical and other cancers.

Transendothelial Transport and Its Role in Therapeutics

Science.gov (United States)

Upadhyay, Ravi Kant

2014-01-01

Present review paper highlights role of BBB in endothelial transport of various substances into the brain. More specifically, permeability functions of BBB in transendothelial transport of various substances such as metabolic fuels, ethanol, amino acids, proteins, peptides, lipids, vitamins, neurotransmitters, monocarbxylic acids, gases, water, and minerals in the peripheral circulation and into the brain have been widely explained. In addition, roles of various receptors, ATP powered pumps, channels, and transporters in transport of vital molecules in maintenance of homeostasis and normal body functions have been described in detail. Major role of integral membrane proteins, carriers, or transporters in drug transport is highlighted. Both diffusion and carrier mediated transport mechanisms which facilitate molecular trafficking through transcellular route to maintain influx and outflux of important nutrients and metabolic substances are elucidated. Present review paper aims to emphasize role of important transport systems with their recent advancements in CNS protection mainly for providing a rapid clinical aid to patients. This review also suggests requirement of new well-designed therapeutic strategies mainly potential techniques, appropriate drug formulations, and new transport systems for quick, easy, and safe delivery of drugs across blood brain barrier to save the life of tumor and virus infected patients. PMID:27355037

Geomorphic Transport Laws and the Statistics of Topography and Stratigraphy

Science.gov (United States)

Schumer, R.; Taloni, A.; Furbish, D. J.

2016-12-01

Geomorphic transport laws take the form of partial differential equations in which sediment motion is a deterministic function of slope. The addition of a noise term, representing unmeasurable, or subgrid scale autogenic forcing, reproduces scaling properties similar to those observed in topography, landforms, and stratigraphy. Here we describe a transport law that generalizes previous equations by permitting transport that is local or non-local in addition to different types of noise. More importantly, we use this transport law to link the character of sediment transport to the statistics of topography and stratigraphy. In particular, we link the origin of the Sadler effect to the evolution of the earth surface via a transport law.

Assessment of ground transportation stress in juvenile Kemp’s ridley sea turtles (Lepidochelys kempii)

Science.gov (United States)

Hunt, Kathleen E.; Innis, Charles J.; Kennedy, Adam E.; McNally, Kerry L.; Davis, Deborah G.; Burgess, Elizabeth A.; Merigo, Constance

2016-01-01

Sea turtle rehabilitation centres frequently transport sea turtles for long distances to move animals between centres or to release them at beaches, yet there is little information on the possible effects of transportation-related stress (‘transport stress’) on sea turtles. To assess whether transport stress is a clinically relevant concern for endangered Kemp’s ridley sea turtles (Lepidochelys kempii), we obtained pre-transport and post-transport plasma samples from 26 juvenile Kemp’s ridley sea turtles that were transported for 13 h (n = 15 turtles) or 26 h (n = 11 turtles) by truck for release at beaches. To control for effects of handling, food restriction and time of day, the same turtles were also studied on ‘control days’ 2 weeks prior to transport, i.e. with two samples taken to mimic pre-transport and post-transport timing, but without transportation. Blood samples were analysed for nine clinical health measures (pH, pCO2, pO2, HCO3, sodium, potassium, ionized calcium, lactate and haematocrit) and four ‘stress-associated’ parameters (corticosterone, glucose, white blood cell count and heterophil-to-lymphocyte ratio). Vital signs (heart rate, respiratory rate and cloacal temperature) were also monitored. Corticosterone and glucose showed pronounced elevations due specifically to transportation; for corticosterone, this elevation was significant only for the longer transport duration, whereas glucose increased significantly after both transport durations. However, clinical health measures and vital signs showed minimal or no changes in response to any sampling event (with or without transport), and all turtles appeared to be in good clinical health after both transport durations. Thus, transportation elicits a mild, but detectable, adrenal stress response that is more pronounced during longer durations of transport; nonetheless, Kemp’s ridley sea turtles can tolerate ground transportation of up to 26 h in good health. These

An Integrated Approach for Reliable Facility Location/Network Design Problem with Link Disruption

Directory of Open Access Journals (Sweden)

Davood Shishebori

2015-05-01

Full Text Available Proposing a robust designed facility location is one of the most effective ways to hedge against unexpected disruptions and failures in a transportation network system. This paper considers the combined facility location/network design problem with regard to transportation link disruptions and develops a mixed integer linear programming formulation to model it. With respect to the probability of link disruptions, the objective function of the model minimizes the total costs, including location costs, link construction costs and also the expected transportation costs. An efficient hybrid algorithm based on LP relaxation and variable neighbourhood search metaheuristic is developed in order to solve the mathematical model. Numerical results demonstrate that the proposed hybrid algorithm has suitable efficiency in terms of duration of solution time and determining excellent solution quality.

Intermodal Barge Transport : Network Design, Nodes and Competitiveness

NARCIS (Netherlands)

Konings, J.W.

2009-01-01

The thesis addresses the opportunities and conditions to increase the market share of intermodal barge transport in Northwest Europe. In particular, it focuses on strategies to improve the performances of the different links of the intermodal transport chain: the barge transport services, the

Issues connected with indirect cost quantification: a focus on the transportation system

Science.gov (United States)

Křivánková, Zuzana; Bíl, Michal; Kubeček, Jan; Vodák, Rostislav

2017-04-01

Transportation and communication networks in general are vital parts of modern society. The economy relies heavily on transportation system performance. A number of people commutes to work regularly. Stockpiles in many companies are being reduced as the just-in-time production process is able to supply resources via the transportation network on time. Natural hazards have the potential to disturb transportation systems. Earthquakes, flooding or landsliding are examples of high-energetic processes which are capable of causing direct losses (i.e. physical damage to the infrastructure). We have focused on quantification of the indirect cost of natural hazards which are not easy to estimate. Indirect losses can also emerge as a result of meteorological hazards with low energy which only seldom cause direct losses, e.g. glaze, snowfall. Whereas evidence of repair work and general direct costs usually exist or can be estimated, indirect costs are much more difficult to identify particularly when they are not covered by insurance agencies. Delimitations of alternative routes (detours) are the most frequent responses to blocked road links. Indirect costs can then be related to increased fuel consumption and additional operating costs. Detours usually result in prolonged travel times. Indirect costs quantification has to therefore cover the value of the time. The costs from the delay are a nonlinear function of travel time, however. The existence of an alternative transportation pattern may also result in an increased number of traffic crashes. This topic has not been studied in depth but an increase in traffic crashes has been reported when people suddenly changed their traffic modes, e.g. when air traffic was not possible. The lost user benefit from those trips that were cancelled or suppressed is also difficult to quantify. Several approaches, based on post-event questioner surveys, have been applied to communities and companies affected by transportation accessibility

Peritoneal Fluid Transport rather than Peritoneal Solute Transport Associates with Dialysis Vintage and Age of Peritoneal Dialysis Patients

Directory of Open Access Journals (Sweden)

Jacek Waniewski

2016-01-01

Full Text Available During peritoneal dialysis (PD, the peritoneal membrane undergoes ageing processes that affect its function. Here we analyzed associations of patient age and dialysis vintage with parameters of peritoneal transport of fluid and solutes, directly measured and estimated based on the pore model, for individual patients. Thirty-three patients (15 females; age 60 (21–87 years; median time on PD 19 (3–100 months underwent sequential peritoneal equilibration test. Dialysis vintage and patient age did not correlate. Estimation of parameters of the two-pore model of peritoneal transport was performed. The estimated fluid transport parameters, including hydraulic permeability (LpS, fraction of ultrasmall pores (αu, osmotic conductance for glucose (OCG, and peritoneal absorption, were generally independent of solute transport parameters (diffusive mass transport parameters. Fluid transport parameters correlated whereas transport parameters for small solutes and proteins did not correlate with dialysis vintage and patient age. Although LpS and OCG were lower for older patients and those with long dialysis vintage, αu was higher. Thus, fluid transport parameters—rather than solute transport parameters—are linked to dialysis vintage and patient age and should therefore be included when monitoring processes linked to ageing of the peritoneal membrane.

Peritoneal Fluid Transport rather than Peritoneal Solute Transport Associates with Dialysis Vintage and Age of Peritoneal Dialysis Patients

Science.gov (United States)

Waniewski, Jacek; Antosiewicz, Stefan; Baczynski, Daniel; Poleszczuk, Jan; Pietribiasi, Mauro; Lindholm, Bengt; Wankowicz, Zofia

2016-01-01

During peritoneal dialysis (PD), the peritoneal membrane undergoes ageing processes that affect its function. Here we analyzed associations of patient age and dialysis vintage with parameters of peritoneal transport of fluid and solutes, directly measured and estimated based on the pore model, for individual patients. Thirty-three patients (15 females; age 60 (21–87) years; median time on PD 19 (3–100) months) underwent sequential peritoneal equilibration test. Dialysis vintage and patient age did not correlate. Estimation of parameters of the two-pore model of peritoneal transport was performed. The estimated fluid transport parameters, including hydraulic permeability (LpS), fraction of ultrasmall pores (α u), osmotic conductance for glucose (OCG), and peritoneal absorption, were generally independent of solute transport parameters (diffusive mass transport parameters). Fluid transport parameters correlated whereas transport parameters for small solutes and proteins did not correlate with dialysis vintage and patient age. Although LpS and OCG were lower for older patients and those with long dialysis vintage, αu was higher. Thus, fluid transport parameters—rather than solute transport parameters—are linked to dialysis vintage and patient age and should therefore be included when monitoring processes linked to ageing of the peritoneal membrane. PMID:26989432

CDC Vital Signs-Safer Food Saves Lives

Centers for Disease Control (CDC) Podcasts

This podcast is based on the November 2015 CDC Vital Signs report. Contaminated food sent to several states can cause multistate outbreaks of foodborne illness and make a lot of people seriously ill. Learn what can be done to prevent and stop outbreaks.

Low Red Blood Cell Vitamin C Concentrations Induce Red Blood Cell Fragility: A Link to Diabetes Via Glucose, Glucose Transporters, and Dehydroascorbic Acid

Directory of Open Access Journals (Sweden)

Hongbin Tu

2015-11-01

Full Text Available Strategies to prevent diabetic microvascular angiopathy focus on the vascular endothelium. Because red blood cells (RBCs are less deformable in diabetes, we explored an original concept linking decreased RBC deformability to RBC ascorbate and hyperglycemia. We characterized ascorbate concentrations from human and mouse RBCs and plasma, and showed an inverse relationship between RBC ascorbate concentrations and deformability, measured by osmotic fragility. RBCs from ascorbate deficient mice were osmotically sensitive, appeared as spherocytes, and had decreased β-spectrin. These aberrancies reversed with ascorbate repletion in vivo. Under physiologic conditions, only ascorbate's oxidation product dehydroascorbic acid (DHA, a substrate for facilitated glucose transporters, was transported into mouse and human RBCs, with immediate intracellular reduction to ascorbate. In vitro, glucose inhibited entry of physiologic concentrations of dehydroascorbic acid into mouse and human RBCs. In vivo, plasma glucose concentrations in normal and diabetic mice and humans were inversely related to respective RBC ascorbate concentrations, as was osmotic fragility. Human RBC β-spectrin declined as diabetes worsened. Taken together, hyperglycemia in diabetes produced lower RBC ascorbate with increased RBC rigidity, a candidate to drive microvascular angiopathy. Because glucose transporter expression, DHA transport, and its inhibition by glucose differed for mouse versus human RBCs, human experimentation is indicated.

TRANSPORT OUTSOURCING AND TRANSPORT COLLABORATION RELATIONSHIP - THE RISK HEDGING PERSPECTIVE

Directory of Open Access Journals (Sweden)

Đurđica M. Stojanović

2015-04-01

Full Text Available Although transport outsourcing decision-making and collaborative transport management (CTM have been “hot topics” for years, their links are still not thoroughly explored. The purpose of this paper is to contribute to a better understanding of the relationship between them. In particular, we focus on the conflicting and complementary features of these concepts with regard to their capability to hedge against transport outsourcing-related risks. Transport outsourcing is often a tool for transferring part of the demand risks from the primary parties in supply chains to transport service providers. However, new relationships introduce some new risks - outsourcing contract risks. It is important to identify, estimate and compare such kinds of risks. Transport collaboration may decrease both the demand risks and the outsourcing contract risks, although the relationship with the latter is more complex. It is used an exploratory research based on a combination of a literature review and empirical examples.

«L'angoixa vital» i la narrativa valenciana de postguerra

Directory of Open Access Journals (Sweden)

Assumpció Bernal

2015-11-01

Full Text Available The purpose of the paper is to analyse the post-war Valencian narrative and the vital agony which is present in almost all the published short stories, especially after Joan Fuster's Recull de contes valencians published in 1958. It also analyses the authors' short stories, the readings, influences and the importance of existencialism and vital pessimism.

«L'angoixa vital» i la narrativa valenciana de postguerra

OpenAIRE

Assumpció Bernal

2015-01-01

The purpose of the paper is to analyse the post-war Valencian narrative and the vital agony which is present in almost all the published short stories, especially after Joan Fuster's Recull de contes valencians published in 1958. It also analyses the authors' short stories, the readings, influences and the importance of existencialism and vital pessimism.

Transportation and Tourism

Science.gov (United States)

2012-08-01

This project explored the link between transportation and tourism in Texas. A session on transit and tourism was organized and conducted as part of the 2012 Texas Transit Conference. Speakers at the session described public transit services oriented ...

Transport theory calculation for a heterogeneous multi-assembly problem by characteristics method with direct neutron path linking technique

International Nuclear Information System (INIS)

Kosaka, Shinya; Saji, Etsuro

2000-01-01

A characteristics transport theory code, CHAPLET, has been developed for the purpose of making it practical to perform a whole LWR core calculation with the same level of calculational model and accuracy as that of an ordinary single assembly calculation. The characteristics routine employs the CACTUS algorithm for drawing ray tracing lines, which assists the two key features of the flux solution in the CHAPLET code. One is the direct neutron path linking (DNPL) technique which strictly connects angular fluxes at each assembly interface in the flux solution separated between assemblies. Another is to reduce the required memory storage by sharing the data related to ray tracing among assemblies with the same configuration. For faster computation, the coarse mesh rebalance (CMR) method and the Aitken method were incorporated in the code and the combined use of both methods showed the most promising acceleration performance among the trials. In addition, the parallelization of the flux solution was attempted, resulting in a significant reduction in the wall-clock time of the calculation. By all these efforts, coupled with the results of many verification studies, a whole LWR core heterogeneous transport theory calculation finally became practical. CHAPLET is thought to be a useful tool which can produce the reference solutions for analyses of an LWR (author)

Economic Analysis Framework for Freight Transportation Based on Florida Statewide Multi-Modal Freight Model

Science.gov (United States)

2018-02-01

Freight transportation plays a vital role in local and regional economy. The markets and businesses from different regions and locations can be connected through freight movements. But it is difficult to quantify the economic contribution of freight ...

Insights into the concept of vitality: associations with participation and societal costs.

NARCIS (Netherlands)

Steenbergen, E.; van Dongen, J.M.; Wendel-Vos, G.C.; Hildebrandt, V.H.; Strijk, J.E.

2016-01-01

BACKGROUND: In healthcare, the focus is currently shifting from someone's disabilities to someone's abilities, which is also evident from the increasing focus on vitality. Vitality (here defined as energy, motivation and resilience) is an often used concept, which also aims at someone's

Development anomaly and non-vitality: Two case reports

Directory of Open Access Journals (Sweden)

Sivakumar Kailasam

2012-01-01

Full Text Available Anatomic aberrations are seen in human dentition. The maxillary incisor region of the permanent dentition where these anatomical aberrations are commonly seen is considered an area of embryonic hazard. Aberrations affecting the internal and external morphology can at times be the cause of complex pathological conditions involving the pulpal and periodontal tissues and can pose a challenge to the clinician for the diagnosis and clinical management. Detecting and treating the anomalies at an early phase is essential as it poses a threat for the loss of vitality of the concerned teeth. The aim of this paper is to highlight the fact two different developmental anomalies of maxillary incisors, namely palatoradicular groove and Turner′s hypoplasia, led to the loss of vitality of the same.

Microwave line of sight link engineering

CERN Document Server

Angueira, Pablo

2012-01-01

A comprehensive guide to the design, implementation, and operation of line of sight microwave link systems The microwave Line of Sight (LOS) transport network of any cellular operator requires at least as much planning effort as the cellular infrastructure itself. The knowledge behind this design has been kept private by most companies and has not been easy to find. Microwave Line of Sight Link Engineering solves this dilemma. It provides the latest revisions to ITU reports and recommendations, which are not only key to successful design but have changed dramatically in

Ocean container transport : an underestimated and critical link in global supply chain performance

NARCIS (Netherlands)

Fransoo, J.C.; Lee, C.Y.

2010-01-01

With supply chains distributed across global markets, ocean container transport now is a critical element of any such supply chain. We identify key characteristics of ocean container transport from a supply chain perspective. We find that unlike continental (road) transport, service offerings tend

Insights into the concept of vitality: associations with participation and societal costs

NARCIS (Netherlands)

Steenbergen, E. van; Dongen, J.M. van; Wendel-Vos, G.C.W.; Hildebrandt, V.H.; Strijk, J.E.

2016-01-01

Background: In healthcare, the focus is currently shifting from someone’s disabilities to someone’s abilities, which is also evident from the increasing focus on vitality. Vitality (here defined as energy, motivation and resilience) is an often used concept, which also aims at someone’s

La teoria del ciclo vitale del risparmio di Modigliani cinquant’anni dopo

Directory of Open Access Journals (Sweden)

Mauro Baranzini

2005-06-01

Full Text Available Nei primi anni ’50 Franco Modigliani, insieme a Richard Brumberg e ad Albert Ando, formulò lateoria del ciclo vitale del consumo e del risparmio, che ha riscosso un enorme e indiscussosuccesso per almeno tre decenni. Tuttavia, a partire dai primi anni ’80 la teoria del ciclo vitale èstata criticata in modo sempre più serrato, per almeno quattro ragioni. La prima consistenell’esistenza di una significativa trasmissione intergenerazionale della ricchezza, da ricondurre acause esogene al modello del ciclo vitale. La seconda ragione è rappresentata dalla crescenteevidenza che i ricchi continuano a risparmiare in misura maggiore rispetto ai meno fortunati,come, in effetti, Keynes sosteneva. Il terzo motivo è che vi sono prove sempre più evidenti,almeno nell’Europa occidentale e in Giappone, che le famiglie giovani, durante i venti e i trentaanni di età, risparmiano una quota positiva e crescente del proprio reddito, e ciò si pone indeciso contrasto con la versione originaria della teoria del ciclo vitale. Infine, numerosi lavoriempirici hanno rilevato che i pensionati accantonano una parte elevata del proprio reddito. Ciòimpone un serio ripensamento dell’approccio della teoria del ciclo vitale, che interessa sia l’analisieconomica sia la politica economica.

Converged wireline and wireless signal transport over optical fibre access links

DEFF Research Database (Denmark)

Tafur Monroy, Idelfonso; Prince, Kamau; Osadchiy, Alexey Vladimirovich

2009-01-01

This article reviews emerging trends in converged optical-wireless communication systems and outline the role that photonic technologies are playing in making the vision of a wireline-wireless converged signal transport network a reality.......This article reviews emerging trends in converged optical-wireless communication systems and outline the role that photonic technologies are playing in making the vision of a wireline-wireless converged signal transport network a reality....

Vitality of optical vortices (Presentation)

CSIR Research Space (South Africa)

Roux, FS

2014-02-01

Full Text Available stream_source_info Roux3_2014.pdf.txt stream_content_type text/plain stream_size 3018 Content-Encoding UTF-8 stream_name Roux3_2014.pdf.txt Content-Type text/plain; charset=UTF-8 Title Vitality of optical vortices F Stef... Roux Presented at Complex Light and Optical Force VIII SPIE Photonics West 2014 Moscone Center, San Francisco, California USA 5 February 2014 CSIR National Laser Centre, Pretoria, South Africa – p. 1/11 Speckle Amplitude Phase – p. 2/11 Vortex...

Vital Signs-Preventing Prescription Drug Overdose

Centers for Disease Control (CDC) Podcasts

2014-07-01

This podcast is based on the July 2014 CDC Vital Signs report. Every day, 46 people in the U.S. die from an overdose of prescription opioid painkillers. Learn what can be done to make painkiller prescribing safer and help prevent overdoses.  Created: 7/1/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 7/1/2014.

Vital Signs-Preventing Pregnancy in Younger Teens

Centers for Disease Control (CDC) Podcasts

This podcast is based on the April 2014 CDC Vital Signs report. Births to teens are declining, still, in 2012, more than 86,000 teens ages 15 to 17 gave birth. This program discusses what health care providers, parents, and teens can do to help prevent teen pregnancy.

Monitoring of Vital Signs with Flexible and Wearable Medical Devices.

Science.gov (United States)

Khan, Yasser; Ostfeld, Aminy E; Lochner, Claire M; Pierre, Adrien; Arias, Ana C

2016-06-01

Advances in wireless technologies, low-power electronics, the internet of things, and in the domain of connected health are driving innovations in wearable medical devices at a tremendous pace. Wearable sensor systems composed of flexible and stretchable materials have the potential to better interface to the human skin, whereas silicon-based electronics are extremely efficient in sensor data processing and transmission. Therefore, flexible and stretchable sensors combined with low-power silicon-based electronics are a viable and efficient approach for medical monitoring. Flexible medical devices designed for monitoring human vital signs, such as body temperature, heart rate, respiration rate, blood pressure, pulse oxygenation, and blood glucose have applications in both fitness monitoring and medical diagnostics. As a review of the latest development in flexible and wearable human vitals sensors, the essential components required for vitals sensors are outlined and discussed here, including the reported sensor systems, sensing mechanisms, sensor fabrication, power, and data processing requirements. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Harmonizing carbon footprint calculation for freight transport chains

NARCIS (Netherlands)

Lewis, A.; Ehrler, V.; Auvinen, H.; Maurer, H.; Davydenko, I.; Burmeister, A.; Seidel, S.; Lischke, A.; Kiel, J.

2016-01-01

The European Commission has set as a target a reduction of 60% in transport greenhouse gas emissions by 2050 [EC 11]. This includes freight transport emissions, which present a particular challenge due to the forecast increase in goods transport linked to future economic growth, the current trend of

Graduate course development : transportation policy and politics.

Science.gov (United States)

2009-08-01

Transportation, public policy, and politics are inextricably linked and have been, in the United States, from : at least 1956, with the birth of the federal highway system and the Interstate Highway Act, if not earlier. : Much of the transportation s...

Grants and Funding for State and Local Transportation

Science.gov (United States)

State and Local Transportation resources are for air quality and transportation government and community leaders. Guidance, strategies and links to grant opportunities are offered for reducing vehicle air pollution, including ozone or smog.

Energía vital. La corriente de Relaciones

Directory of Open Access Journals (Sweden)

Stephen Gudeman

2013-07-01

Full Text Available Vital energy' is a central idea in the economies of Panama and Colombia. Known as 'strength' or 'force', and assembled from the environment, this current connects all activities in the local economies and establishes relationships, from kin to strangers. Humans compose vital energy, but its sources are limited, and it is expended in use. Its availability is a gift from God and part of the unpredictable fortune that everyone faces. This economy exhibits a contrast between a social current and a market currency. It offers a materialist perspective, provides a critique of standard economics, suggests that sharing rather than reciprocity or rational choice is the 'fundamental' economic practice, and shows how an economy may be a kind of ritual legitimated by a belief in divine power that is displayed through personal fortune.

Transport and transformation of genetic information in the critical zone: The case of antibiotic resistance genes

Science.gov (United States)

Zhu, Y. G.

2015-12-01

In addition to material and energy flows, the dynamics and functions of the Earth's critical zone are intensively mediated by biological actions performed by diverse organisms. These biological actions are modulated by the expression of functional genes and their translation into enzymes that catalyze geochemical reactions, such as nutrient turnover and pollutant biodegradation. Although geobiology, as an interdisciplinary research area, is playing and vital role in linking biological and geochemical processes at different temporal and spatial scales, the distribution and transport of functional genes have rarely been investigated from the Earth's critical zone perspectives. To illustrate the framework of studies on the transport and transformation of genetic information in the critical zone, antibiotic resistance is taken as an example. Antibiotic resistance genes are considered as a group of emerging contaminants, and their emergence and spread within the critical zone on one hand are induced by anthropogenic activities, and on other hand are threatening human health worldwide. The transport and transformation of antibiotic resistance genes are controlled by both horizontal gene transfer between bacterial cells and the movement of bacteria harboring antibiotic resistance genes. In this paper, the fate and behavior of antibiotic resistance genes will be discussed in the following aspects: 1) general overview of environmental antibiotic resistance; 2) high through quantification of the resistome in various environmental media; 3) pathways of resistance gene flow within the critical zone; and 4) potential strategies in mitigating antibiotic resistance, particularly from the critical zone perspectives.

CDC Vital Signs-Heart Age

Centers for Disease Control (CDC) Podcasts

2015-09-01

This podcast is based on the September 2015 CDC Vital Signs report. Your heart age is the age of your heart and blood vessels as a result of your risk factors for heart attack and stroke. If you smoke or have high blood pressure, your heart age will be much higher than your actual age. Learn what you can do to lower your heart age and keep it low.  Created: 9/1/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/1/2015.

CDC Vital Signs-Hispanic Health

Centers for Disease Control (CDC) Podcasts

2015-05-05

This podcast is based on the May 2015 CDC Vital Signs report. About one in six people living in the U.S. are Hispanic. The two leading causes of death in this group are heart disease and cancer, accounting for two out of five deaths. Unfortunately, many Hispanics face considerable barriers to getting high quality health care, including language and low income. Learn what can be done to reduce the barriers.  Created: 5/5/2015 by Office of Minority Health & Health Equity (OMHHE).   Date Released: 5/5/2015.

Exercise: A vitally important prescription.

Science.gov (United States)

Hechanova, Rachel L; Wegler, Jennifer L; Forest, Christopher P

2017-04-01

Sedentary lifestyles and low physical activity have led to rising health concerns and increasing mortality risks. With the growing concern of the inactivity of adult Americans, it is important that physical activity be promoted to prevent disease and reduce health risks. This article reviews the benefits of physical activity and the steps that primary care providers should take to evaluate physical activity as the fifth vital sign in every patient encounter. The 5A's (assess, advise, agree, assist, and arrange) should be applied in order to implement an exercise prescription into the practice of medicine.

Entrepreneurship education: a vital instrument for youth ...

African Journals Online (AJOL)

The concern of this paper is to explore Entrepreneurship Education (EE) as one of the vital tools for youth empowerment, industrial development and consolidation of national integration in Nigeria. To achieve this feat, the paper takes its roots from the role of EE in youth empowerment programmes, national integration and ...

Mediating effect of Facebook addiction on the relationship between subjective vitality and subjective happiness.

Science.gov (United States)

Uysal, Recep; Satici, Seydi Ahmet; Akin, Ahmet

2013-12-01

This study examined the mediating effects of Facebook addiction on the relationship between subjective vitality and subjective happiness. 297 university students (157 women, 140 men; M age = 20.1 yr., SD = 1.3) were administered the Facebook Addiction Scale, the Subjective Vitality Scale, and the Subjective Happiness Scale. Hierarchical regression analysis showed that Facebook addiction partially mediated the relationship between subjective vitality and subjective happiness.

CDC Vital Signs-Protect Patients from Antibiotic Resistance

Centers for Disease Control (CDC) Podcasts

This podcast is based on the March 2016 CDC Vital Signs report. Patients can get serious healthcare-associated infections, or HAIs, while receiving medical treatment in a healthcare facility. Learn how to prevent healthcare-associated infections.

CDC Vital Signs-Too Loud for Too Long!

Centers for Disease Control (CDC) Podcasts

This podcast is based on the February 2017 CDC Vital Signs report. Being around too much loud noise-like a leaf blower or rock concert-can cause permanent hearing loss. Learn how to prevent hearing loss.

Cascade of links in complex networks

Energy Technology Data Exchange (ETDEWEB)

Feng, Yeqian; Sun, Bihui [Department of Management Science, School of Government, Beijing Normal University, 100875 Beijing (China); Zeng, An, E-mail: anzeng@bnu.edu.cn [School of Systems Science, Beijing Normal University, 100875 Beijing (China)

2017-01-30

Cascading failure is an important process which has been widely used to model catastrophic events such as blackouts and financial crisis in real systems. However, so far most of the studies in the literature focus on the cascading process on nodes, leaving the possibility of link cascade overlooked. In many real cases, the catastrophic events are actually formed by the successive disappearance of links. Examples exist in the financial systems where the firms and banks (i.e. nodes) still exist but many financial trades (i.e. links) are gone during the crisis, and the air transportation systems where the airports (i.e. nodes) are still functional but many airlines (i.e. links) stop operating during bad weather. In this letter, we develop a link cascade model in complex networks. With this model, we find that both artificial and real networks tend to collapse even if a few links are initially attacked. However, the link cascading process can be effectively terminated by setting a few strong nodes in the network which do not respond to any link reduction. Finally, a simulated annealing algorithm is used to optimize the location of these strong nodes, which significantly improves the robustness of the networks against the link cascade. - Highlights: • We propose a link cascade model in complex networks. • Both artificial and real networks tend to collapse even if a few links are initially attacked. • The link cascading process can be effectively terminated by setting a few strong nodes. • A simulated annealing algorithm is used to optimize the location of these strong nodes.

Cascade of links in complex networks

International Nuclear Information System (INIS)

Feng, Yeqian; Sun, Bihui; Zeng, An

2017-01-01

Cascading failure is an important process which has been widely used to model catastrophic events such as blackouts and financial crisis in real systems. However, so far most of the studies in the literature focus on the cascading process on nodes, leaving the possibility of link cascade overlooked. In many real cases, the catastrophic events are actually formed by the successive disappearance of links. Examples exist in the financial systems where the firms and banks (i.e. nodes) still exist but many financial trades (i.e. links) are gone during the crisis, and the air transportation systems where the airports (i.e. nodes) are still functional but many airlines (i.e. links) stop operating during bad weather. In this letter, we develop a link cascade model in complex networks. With this model, we find that both artificial and real networks tend to collapse even if a few links are initially attacked. However, the link cascading process can be effectively terminated by setting a few strong nodes in the network which do not respond to any link reduction. Finally, a simulated annealing algorithm is used to optimize the location of these strong nodes, which significantly improves the robustness of the networks against the link cascade. - Highlights: • We propose a link cascade model in complex networks. • Both artificial and real networks tend to collapse even if a few links are initially attacked. • The link cascading process can be effectively terminated by setting a few strong nodes. • A simulated annealing algorithm is used to optimize the location of these strong nodes.

Quality management for the international transportation of non-human primates

Directory of Open Access Journals (Sweden)

David B. Elmore

2008-03-01

Full Text Available Safe and humane transportation of live animals requires dedicated, informed personnel who carefully plan and attend to the details of appropriate animal care and handling throughout the shipping process. Specifically, although transportation of non-human primates shares goals common to all live animal transport, it also poses unique challenges stemming from the nature of these animals. Some of these unique challenges of transporting non-human primates, include the impact of public perception of non-human primates as cargo, maintaining biosecurity of non-human primate cargo, safety of both the non-human primate and public contacts, meeting the vital husbandry needs of varying species of non-human primates and compliance with numerous regulatory agencies, which may have overlapping responsibilities. This discussion will focus on these important considerations, as they relate to the legal international transportation of non-human primates for scientific use.

[Modifications of vital signs during hygiene care in intensive care patients: an explorative study].

Science.gov (United States)

Lucchini, Alberto; Giacovelli, Matteo; Elli, Stefano; Gariboldi, Roberto; Pelucchi, Giulia; Bondi, Herman; Brambilla, Daniela

2009-01-01

Hygiene care in critical patients may alter vital signs. Aim of this paper is to measure vital signs and their modifications in critical patients during hygiene care and measure differences with pre and post hygiene values. Vital signs of 6 patients two hours before, during and 90 minutes after hygienic care were measured. During and 2 hours after the end of hygiene a modification of vital signs was observed compared to basic values (mean values during/90 min after, compared to baseline): heart rate +11.20%/ +1.48; systolic blood pressure +22.68%/+1.56; arterial capillary saturimetry -4.31/+0.27, Respiratory frequency +8.10/+2.66, tidal volume +4,04/-7,51, CO2 min/vol +5,34/- 22.33, bladder temperature -0.85/-0.60. Hygiene care in critical care patients may significantly alter vital signs. Therefore a strict haemodinamic and respiratory monitoring is warranted as well as protocols for the management of sedation and of vasoactive support.

Estimating survival probabilities by exposure levels: utilizing vital statistics and complex survey data with mortality follow-up.

Science.gov (United States)

Landsman, V; Lou, W Y W; Graubard, B I

2015-05-20

We present a two-step approach for estimating hazard rates and, consequently, survival probabilities, by levels of general categorical exposure. The resulting estimator utilizes three sources of data: vital statistics data and census data are used at the first step to estimate the overall hazard rate for a given combination of gender and age group, and cohort data constructed from a nationally representative complex survey with linked mortality records, are used at the second step to divide the overall hazard rate by exposure levels. We present an explicit expression for the resulting estimator and consider two methods for variance estimation that account for complex multistage sample design: (1) the leaving-one-out jackknife method, and (2) the Taylor linearization method, which provides an analytic formula for the variance estimator. The methods are illustrated with smoking and all-cause mortality data from the US National Health Interview Survey Linked Mortality Files, and the proposed estimator is compared with a previously studied crude hazard rate estimator that uses survey data only. The advantages of a two-step approach and possible extensions of the proposed estimator are discussed. Copyright © 2015 John Wiley & Sons, Ltd.

Clinical relevance of routinely measured vital signs in hospitalized patients: a systematic review

NARCIS (Netherlands)

Storm-Versloot, Marja N.; Verweij, Lotte; Lucas, Cees; Ludikhuize, Jeroen; Goslings, J. Carel; Legemate, Dink A.; Vermeulen, Hester

2014-01-01

Conflicting evidence exists on the effectiveness of routinely measured vital signs on the early detection of increased probability of adverse events. To assess the clinical relevance of routinely measured vital signs in medically and surgically hospitalized patients through a systematic review.

Vitalism, purpose and superstition.

Science.gov (United States)

Lindeman, Marjaana; Saher, Marieke

2007-02-01

Developmental studies have shown that children assign purpose to objects more liberally than adults, and that they explain biological processes in terms of vitalistic causality. This study tested the hypothesis that similar misconceptions can be found among superstitious adults. The results from 116 superstitious and 123 sceptical individuals showed that more than sceptics, superstitious individuals attributed purpose to objects, and explained biological processes in terms of organ intentionality and energy transmission. In addition, they thought of energy as a vital force, attributing life and mental properties to it. These conceptual confusions were positively associated to all types of superstitions as well as belief in alternative medicine. The results support the argument that category mistakes and ontological confusions underlie superstitious and vitalistic thinking.

FAA airborne data link human factors research plan

Science.gov (United States)

1993-07-01

This report contains a five-year plan to perform research of human factors issues and topics : related to Data Link implementations in general aviation and transport category aircraft. : Elements such as resource allocation and management and coordin...

Vital Signs-Physical Activity and Adults with Disabilities

Centers for Disease Control (CDC) Podcasts

This podcast is based on the May 2014 CDC Vital Signs report. Adults with disabilities who get no aerobic physical activity are 50 percent more likely to have heart disease, stroke, diabetes, or cancer. Learn what you can do to help.

Fiber optic based multiparametric spectroscopy in vivo: Toward a new quantitative tissue vitality index

Science.gov (United States)

Kutai-Asis, Hofit; Barbiro-Michaely, Efrat; Deutsch, Assaf; Mayevsky, Avraham

2006-02-01

In our previous publication (Mayevsky et al SPIE 5326: 98-105, 2004) we described a multiparametric fiber optic system enabling the evaluation of 4 physiological parameters as indicators of tissue vitality. Since the correlation between the various parameters may differ in various pathophysiological conditions there is a need for an objective quantitative index that will integrate the relative changes measured in real time by the multiparametric monitoring system into a single number-vitality index. Such an approach to calculate tissue vitality index is critical for the possibility to use such an instrument in clinical environments. In the current presentation we are reporting our preliminary results indicating that calculation of an objective tissue vitality index is feasible. We used an intuitive empirical approach based on the comparison between the calculated index by the computer and the subjective evaluation made by an expert in the field of physiological monitoring. We used the in vivo brain of rats as an animal model in our current studies. The rats were exposed to anoxia, ischemia and cortical spreading depression and the responses were recorded in real time. At the end of the monitoring session the results were analyzed and the tissue vitality index was calculated offline. Mitochondrial NADH, tissue blood flow and oxy-hemoglobin were used to calculate the vitality index of the brain in vivo, where each parameter received a different weight, in each experiment type based on their significance. It was found that the mitochondrial NADH response was the main factor affected the calculated vitality index.

Green Propulsion Technologies for Advanced Air Transports

Science.gov (United States)

Del Rosario, Ruben

2015-01-01

Air transportation is critical to U.S. and Global economic vitality. However, energy and climate issues challenge aviations ability to be sustainable in the long term. Aviation must dramatically reduce fuel use and related emissions. Energy costs to U.S. airlines nearly tripled between 1995 and 2011, and continue to be the highest percentage of operating costs. The NASA Advanced Air Transports Technology Project addresses the comprehensive challenge of enabling revolutionary energy efficiency improvements in subsonic transport aircraft combined with dramatic reductions in harmful emissions and perceived noise to facilitate sustained growth of the air transportation system. Advanced technologies and the development of unconventional aircraft systems offer the potential to achieve these improvements. The presentation will highlight the NASA vision of revolutionary systems and propulsion technologies needed to achieve these challenging goals. Specifically, the primary focus is on the N+3 generation; that is, vehicles that are three generations beyond the current state of the art, requiring mature technology solutions in the 2025-30 timeframe, which are envisioned as being powered by Hybrid Electric Propulsion Systems.

Superficie Específica y Estado Vital de la Materia

Directory of Open Access Journals (Sweden)

J. Hernando Ordoñez

1992-03-01

Full Text Available

Se propone reemplazar el término de materia viva por el de estado vital de la materia por considerarlo adecuado, pues la materia es la misma, lo que cambia es su estado. Se estudia la relación entre la superficie específica y el estado vital de la materia. Constante del estado vital y el valor crítico de la superficie específica. Qué es la fuerza de inducción vital? Diferenciación funcional de las células. Cómo regula la unidad biológica su superficie específica? La materia que piensa es el fenómeno más grandioso de la creación.

Sin entrar en disquisiciones sobre la naturaleza, manifestaciones y formas de la energía, me permito hacer unas a manera de divagaciones sobre los diferentes estados de la materia, que es una forma de la energía.

Estados de la materia

Sabemos que la mínima porción de la materia es el átomo, que tiene una composición compleja, que no es del caso estudiar. Los átomos pueden existir aislados y estar en lo que llamamos estado iónico. Si los átomos se juntan, forman moléculas, y su existencia constituye el estado molecular. Si las moléculas se juntan, forman complejos más grandes y tendremos las micelas, que constituyen el estado coloidal.

Hasta aquí nuestros conocimientos nos son familiares, triviales. Pero hay un estado más complejo, en el cual entra materia en estado iónico, molecular y coloidal entrelazados entre sí, con propiedades totalmente diferentes. La materia en este estado adquiere caracteres extraordinarios tales como el de crecer, reproducirse, independizarse de las leyes físicas, puede autorregular su composición química, autorregular sus manifestaciones físicas, reaccionar ante los estímulos más variados, puede llegar hasta alturas inconcebibles integrando ideas. A este estado fue al que llamé en publicación anterior (1 estado vital, concepto que fue corroborado más ‘tarde por J.R. Brown (2 cuando me coment

Single liposome analysis of peptide translocation by the ABC transporter TAPL

NARCIS (Netherlands)

Zollmann, Tina; Moiset Coll, Gemma; Tumulka, Franz; Tampé, Robert; Poolman, Bert; Abele, Rupert

2015-01-01

ATP-binding cassette (ABC) transporters use ATP to drive solute transport across biological membranes. Members of this superfamily have crucial roles in cell physiology, and some of the transporters are linked to severe diseases. However, understanding of the transport mechanism, especially of human

Poder vital e o legado de florence nightingale no processo saúdedoença: revisão integrativa The vital power and the legacy of florence nightingale in the health-disease process: integrative review

Directory of Open Access Journals (Sweden)

Marli Aparecida Rocha Souza

2017-01-01

Full Text Available Objetivo:.Caracterizar as evidências científicas nacionais dos últimos dez anos sobre Florence Nightingale e o poder vital e sua aplicabilidade na enfermagem, além de identificar os conceitos sobre poder vital. Método:.Revisão integrativa da literatura de artigos nacionais completos, por meio de quatro bases de dados. Foram selecionados sete artigos após a aplicação dos critérios de inclusão e exclusão. Da análise surgiram os temas sobre o legado de Florence e a ação do meio ambiente interno e externo sobre o poder vital. Resultados:.A maioria dos estudos focou o ambiente de inserção do indivíduo como fortalecer do poder vital e esta classificada como força interior. Conclusão:.Os profissionais de enfermagem ocupam um papel imprescindível na observação em manter o ambiente onde o paciente está inserido, favorecendo o fortalecimento do poder vital, destacando a presença do acompanhante como fortalecedor desse poder vital no processo de hospitalização.Descritores: Puerpério, Parto, Enfermagem.

Vital Signs – Childhood Obesity

Centers for Disease Control (CDC) Podcasts

2013-08-06

This podcast is based on the August 2013 CDC Vital Signs report. The rate of obesity among low-income preschoolers has declined, but one in eight is still obese. This program briefly discusses what can be done.  Created: 8/6/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 8/6/2013.

Output variability caused by random seeds in a multi-agent transport simulation model

DEFF Research Database (Denmark)

Paulsen, Mads; Rasmussen, Thomas Kjær; Nielsen, Otto Anker

2018-01-01

Dynamic transport simulators are intended to support decision makers in transport-related issues, and as such it is valuable that the random variability of their outputs is as small as possible. In this study we analyse the output variability caused by random seeds of a multi-agent transport...... simulator (MATSim) when applied to a case study of Santiago de Chile. Results based on 100 different random seeds shows that the relative accuracies of estimated link loads tend to increase with link load, but that relative errors of up to 10 % do occur even for links with large volumes. Although...

Identification of Vital Areas at Nuclear Facilities. Technical Guidance (French Edition)

International Nuclear Information System (INIS)

2015-01-01

nuclear installations against sabotage are contained in IAEA Nuclear Security Series No. 13, Nuclear Security Recommendations on Physical Protection of Nuclear Material and Nuclear Facilities (INFCIRC/225/Revision 5). After the attacks of 11 September 2001, the perception of the potential terrorist threat to nuclear installations changed significantly, and the IAEA initiated an effort to develop a series of guidance publications on the security of nuclear and radioactive material and facilities. This publication presents a structured approach to identifying the areas that contain equipment, systems, and components to be protected against sabotage. It specifically provides detailed guidance with regard to the identification of vital areas, that is, the areas to be protected in high consequence facilities. However, the process described is applicable to the identification of areas that should be protected at any nuclear facility. The method builds upon safety analyses to develop sabotage logic models for sabotage scenarios that could cause unacceptable radiological consequences. The sabotage actions represented in the logic models are linked to the areas from which they can be accomplished. The logic models are then analysed to determine areas that should be protected to prevent these unacceptable radiological consequences

Vitality at work and its associations with lifestyle, self-determination, organizational culture, and with employees' performance and sustainable employability.

Science.gov (United States)

van Scheppingen, Arjella R; de Vroome, Ernest M M; Ten Have, Kristin C J M; Zwetsloot, Gerard I J M; Wiezer, Noortje; van Mechelen, Willem

2015-01-01

Vitality at work is an important factor for optimal functioning and sustainable employability. To date, knowledge on how to promote vitality at work is fragmented. Contribute to knowledge on how to promote vitality at work. Determinants of vitality at work are identified from three scientific fields, and used in a comprehensive model. Regression analyses on cross-sectional data from a Dutch dairy company (N= 629) are performed to examine the associations between these factors, vitality at work, and employees' perceived effective personal functioning and sustainable employability. Vitality at work is most strongly associated with basic psychological needs of self-determination, but also with healthy lifestyle behavior, having a balanced workstyle, and social capital. Vitality at work is also associated with effective personal functioning and with sustainable employability. The study confirms the multifactorial nature of vitality at work. Since organizational culture may support self-determination, and cultural aspects themselves are positively associated with vitality, organizational culture seems particular important in promoting vitality at work. Additionally, a healthy lifestyle appears important. The associations between vitality at work and effective personal functioning and sustainable employability endorse the combined health-based, business-related and societal importance of vitality at work.

The Arabidopsis thaliana RNA editing factor SLO2, which affects the mitochondrial electron transport chain, participates in multiple stress and hormone responses.

Science.gov (United States)

Zhu, Qiang; Dugardeyn, Jasper; Zhang, Chunyi; Mühlenbock, Per; Eastmond, Peter J; Valcke, Roland; De Coninck, Barbara; Oden, Sevgi; Karampelias, Michael; Cammue, Bruno P A; Prinsen, Els; Van Der Straeten, Dominique

2014-02-01

Recently, we reported that the novel mitochondrial RNA editing factor SLO2 is essential for mitochondrial electron transport, and vital for plant growth through regulation of carbon and energy metabolism. Here, we show that mutation in SLO2 causes hypersensitivity to ABA and insensitivity to ethylene, suggesting a link with stress responses. Indeed, slo2 mutants are hypersensitive to salt and osmotic stress during the germination stage, while adult plants show increased drought and salt tolerance. Moreover, slo2 mutants are more susceptible to Botrytis cinerea infection. An increased expression of nuclear-encoded stress-responsive genes, as well as mitochondrial-encoded NAD genes of complex I and genes of the alternative respiratory pathway, was observed in slo2 mutants, further enhanced by ABA treatment. In addition, H2O2 accumulation and altered amino acid levels were recorded in slo2 mutants. We conclude that SLO2 is required for plant sensitivity to ABA, ethylene, biotic, and abiotic stress. Although two stress-related RNA editing factors were reported very recently, this study demonstrates a unique role of SLO2, and further supports a link between mitochondrial RNA editing events and stress response.

CDC Vital Signs: HIV Among Youth in the US

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

PROBLEMS OF HARMONIZATION OF THE GOALS AND VITAL INTERESTS IN ENSURING SOCIO-ECONOMIC SECURITY

Directory of Open Access Journals (Sweden)

D. N. Shvayba1

2017-01-01

Full Text Available Formation of an independent democratic Belarusian state is inextricably linked with transformations in all aspects of public life and, first of all, in economy. Economic reforms in Belarus are directed on creation of socially oriented market economic system, which will ensure the most efficient usage of resources at minimum social cost. In the social economy concepts of “equality” and “poverty” are considered as basic ones. Social security services are based on these concepts and role of the social security in any country is to reduce poverty and increase equality. In modern world poverty is uniquely associated with a low level of economic development and its eradication is the first step on the path to economic growth. As for inequality, such clear connection of this concept with economic development can not be traced. There are various theories explaining the impact of inequality on economic growth. However, they cannot be considered satisfactory because they predict opposite results. Several studies have universally postulated a security as protection of vital interests of a human being, society and State from internal and external threats. Vital interests comprise a set of needs and satisfaction of these needs reliably ensures existence and possibility of progressive development of a human being, society and State which are the main objects of the security. Presence of a hierarchical structure for organization of the system or its subsystems is an essential feature for any socio-economic system. The economy is a poly-hierarchical system. When considering the hierarchical structure of production management it is important to consider one property of the economic system that is incompleteness of information.

Vital Signs – Prescription Painkiller Overdoses

Centers for Disease Control (CDC) Podcasts

This podcast is based on the July 2013 CDC Vital Signs report. Prescription painkiller overdoses are an under-recognized and growing problem among women. This program includes things that women and health care providers can do to reduce the risk of overdose.

Expert Talks: Understanding civil registration and vital statistics ...

International Development Research Centre (IDRC) Digital Library (Canada)

2017-09-13

Sep 13, 2017 ... Case studies and successes in CRVS reform. Cambodia, New Zealand, Peru, Uganda, and others offer important lessons in strengthening civil registration and vital statistics systems. These interviews feature innovative case studies that have led to new and improved CRVS approaches.

Vitality of oligozoospermic semen samples is improved by both swim-up and density gradient centrifugation before cryopreservation.

Science.gov (United States)

Counsel, Madeleine; Bellinge, Rhys; Burton, Peter

2004-05-01

To ascertain whether washing sperm from oligozoospermic and normozoospermic samples before cryopreservation improves post-thaw vitality. Normozoospermic (n = 18) and oligozoospermic (n = 16) samples were divided into three aliquots. The first aliquot remained untreated and the second and third aliquots were subjected to the swim-up and discontinuous density gradient sperm washing techniques respectively. Vitality staining was performed, samples mixed with cryopreservation media and frozen. Spermatozoa were thawed, stained, and vitality quantified and expressed as the percentage of live spermatozoa present. Post-thaw vitality in untreated aliquots from normozoospermic samples (24.9% +/- 2.3; mean +/- SEM) was significantly higher (unpaired t-tests; P vitality was significantly higher after swim-up in normozoospermic samples (35.6% +/- 2.1; P vitality in oligozoospermic (22.4% +/- 1.0; P vitality in cryopreserved oligozoospermic samples was improved by both the swim-up and density gradient centrifugation washing techniques prior to freezing.

TIROTOXICOSIS GESTACIONAL: PATOLOGIA CON RIESGO VITAL

OpenAIRE

Valdés R.,Enrique; Pilasi M.,Carlos; Núñez U.,Tatiana

2003-01-01

Se presenta un caso clínico con diagnóstico final de Tirotoxicosis gestacional que debuta con una complicación excepcional, insuficiencia cardíaca congestiva e hipertensión pulmonar severa. Se presenta la experiencia del Hospital Clínico de la Universidad de Chile, proponiendo que su diagnóstico y tratamiento oportunos son la base del pronóstico de esta patología de riesgo vital para el binomio madre-hijo

Multimodal Transportation Simulation for Emergencies using the Link Transmission Model

NARCIS (Netherlands)

van der Gun, J.P.T.

2018-01-01

Emergencies disrupting urban transportation systems cause management problems for authorities. This thesis develops simulation methods that permit analysis thereof and evaluation of candidate management plans, tested in three case studies. It formulates a methodological framework using agent-based

Novel hydroxyapatite biomaterial covalently linked to raloxifene.

Science.gov (United States)

Meme, L; Santarelli, A; Marzo, G; Emanuelli, M; Nocini, P F; Bertossi, D; Putignano, A; Dioguardi, M; Lo Muzio, L; Bambini, F

2014-01-01

Since raloxifene, a drug used in osteoporosis therapy, inhibits osteoclast, but not osteoblast functions, it has been suggested to improve recovery during implant surgery. The present paper describes an effective method to link raloxifene, through a covalent bond, to a nano-Hydroxyapatite-based biomaterial by interfacing with (3-aminopropyl)-Triethoxysilane as assessed by Infra Red-Fourier Transformed (IR-FT) spectroscopy and Scanning Electron Microscope (SEM). To evaluate the safety of this modified new material, the vitality of osteoblast-like cells cultured with the new biomaterial was then investigated. Raloxifene-conjugated HAbiomaterial has been shown to be a safe material easy to obtain which could be an interesting starting point for the use of a new functional biomaterial suitable in bone regeneration procedures.

New buses and links for data acquisition

International Nuclear Information System (INIS)

Mueller, H.; Bogaerts, A.; McLaren, R.; Parkman, C.; Linnhoefer, D.

1992-01-01

Bus standards for data acquisition have been vital for the construction and operation of medium and large HEP experiments. The recent industry bus standardisation effort will soon release the next generation of high performance buses and links for scalable systems. Prototype components, VLSI chips and board-level systems are already announced. Layers of the new bus specifications cover wide areas of applications and provide possibilities to define specific bus profiles by interest groups. New, innovative solutions which are needed for high rate experiments are becoming visible. These will provide novel architectural possibilities, very high bandwidth, fast silicon, industry support and new metric mechanical standards. Interconnected via standard bridges, different bus standards can be used to cover the varying requirements from the front ends to the computers. (orig.)

The naphthoquinones, vitamin K3 and its structural analog plumbagin, are substrates of the multidrug resistance-linked ABC drug transporter ABCG2

Science.gov (United States)

Shukla, Suneet; Wu, Chung-Pu; Nandigama, Krishnamachary; Ambudkar, Suresh V.

2008-01-01

Vitamin K3 (Menadione; 2-methyl-1,4-naphthoquinone) is a structural precursor of vitamins K1 and K2 which are essential for blood clotting. The naturally occurring structural analog of this vitamin, plumbagin (5-hydroxy-menadione), is known to modulate cellular proliferation, apoptosis, carcinogenesis, and radioresistance. We, here, report that both vitamin K3 and plumbagin are substrates of the multidrug resistance-linked ATP binding cassette (ABC) drug transporter, ABCG2. Vitamin K3 and plumbagin specifically inhibited the ABCG2-mediated efflux of mitoxantrone, but did not have any effect on the ABCB1-mediated efflux of rhodamine 123. This inhibition of ABCG2 function was due to their interaction at the substrate-binding site(s). They inhibited the binding of [125I]-Iodoarylazidoprazosin (IAAP), a substrate of ABCG2, to this transporter in a concentration-dependent manner with IC50 values of 7.3 and 22.6 μM, respectively, but had no effect on the binding of this photoaffinity analog to ABCB1. Both compounds stimulated ABCG2-mediated ATP hydrolysis and also inhibited the mitoxantrone-stimulated ATPase activity of this transporter, but did not have any significant effect on the ATPase activity of ABCB1. In a cytotoxicity assay, ABCG2-expressing HEK cells were 2.8- and 2.3-fold resistant to plumbagin and vitamin K3, respectively, compared to the control cells, suggesting that they are substrates of this transporter. Collectively, these data demonstrate for the first time that vitamin K3 is a substrate of the ABCG2 transporter. Thus, ABCG2 may have a role in the regulation of vitamin K3 levels in the body. In addition, vitamin K3 and its structural derivative, plumbagin, could potentially be used to modulate ABCG2 function. PMID:18065489

The cross-cultural importance of satisfying vital needs.

Science.gov (United States)

Alvarez, Allen Andrew A

2009-11-01

Ethical beliefs may vary across cultures but there are things that must be valued as preconditions to any cultural practice. Physical and mental abilities vital to believing, valuing and practising a culture are such preconditions and it is always important to protect them. If one is to practise a distinct culture, she must at least have these basic abilities. Access to basic healthcare is one way to ensure that vital abilities are protected. John Rawls argued that access to all-purpose primary goods must be ensured. Amartya Sen and Martha Nussbaum claim that universal capabilities are what resources are meant to enable. Len Doyal and Ian Gough identify physical health and autonomy as basic needs of every person in every culture. When we disagree on what to prioritize, when resources to satisfy competing demands are scarce, our common needs can provide a point of normative convergence. Need-based rationing, however, has been criticized for being too indeterminate to give guidance for deciding which healthcare services to prioritize and for tending to create a bottomless-pit problem. But there is a difference between needing something (first-order need) and needing to have the ability to need (second-order need). Even if we disagree about which first-order need to prioritize, we must accept the importance of satisfying our second-order need to have the ability to value things. We all have a second-order need for basic healthcare as a means to protect our vital abilities even if we differ in what our cultures consider to be particular first-order needs.

Logistic innovations in transport

Directory of Open Access Journals (Sweden)

Mirosław Antonowicz

2014-03-01

Full Text Available Introduction: The article discusses the issue of logistic innovations in transport. The essentials of logistic innovations in transport together with some examples of specific innovations are presented. The role of the client's needs in transport innovations is indicated. The most vital postulates affecting the innovativeness of shipping companies and derived from the author's experience as well as scholarly publications, are time, safety, reliability as well as comprehensiveness of service offer. Following the analysis of the issue, and on the grounds of Kaizen's and Lean's method, the concept of continuous innovations is suggested as very useful for the development of transport. The potential of clusters as the source of logistic innovations in transport is emphasised. Methods: The discussion of the issue was preceded by the author's analysis of written sources on innovativeness, the evaluation of ratings of innovativeness as well as the analysis of rewarded innovative solutions in transport subsequent to the businesses participation in the programme of innovative solutions in transport. The role of innovation practical business operations is argued following the analysis of some strategic documents such as: 2011 White Paper and the Strategy for the Development of Transport by 2020 adopted by the Polish government in 2013. Aim: The aim of the article is to present the role and significance of the issue of logistic innovations in transport and to cite instances of practical solutions implemented by shipping companies, the solutions which resulted in measurable effects. Following the author's observation of the instances of innovative solutions as well as his analysis of the ratings of innovativeness, the article aims to present the conclusions as for the specific kinds of activities which are indispensable to foster innovativeness in transport. Conclusions: The conclusions derived from the author's analyses and observations show that logistic

Vitality preservation of an anomalous maxillary central incisor after endodontic therapy.

Science.gov (United States)

Kaufman, A Y; Kaffe, I; Littner, M M

1984-06-01

Endodontic treatment of a case of fused immature central incisor with a supernumerary tooth with dens in dente is described. Although a chronic dentoalveolar abscess was diagnosed, vitality test signs were positive. Treatment consisted of pulpotomy with calcium hydroxide paste; after 2 1/2 months a permanent root canal filling was placed in the amputated part. Follow-up 2 years postoperatively indicated that the tooth has maintained its vitality. The periapical area is completely healed, and apical closure is evident.

CDC Vital Signs-Communication Can Save Lives

Centers for Disease Control (CDC) Podcasts

2015-08-04

This podcast is based on the August 2015 CDC Vital Signs report. Antibiotic-resistant germs cause at least 23,000 deaths each year. Learn how public health authorities and health care facilities can work together to save lives.  Created: 8/4/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 8/4/2015.

CDC Vital Signs-Hospital Actions Affect Breastfeeding

Centers for Disease Control (CDC) Podcasts

2015-10-06

This podcast is based on the October 2015 CDC Vital Signs report. Hospitals can implement the Ten Steps to Successful Breastfeeding to be designated as "Baby-Friendly" and support more moms in a decision to breastfeed.  Created: 10/6/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 10/6/2015.

VITAL: Vanguard Investigations of Therapeutic Approaches to Lung Cancer

National Research Council Canada - National Science Library

Hong, Waun K; Lotan, Reuben; Stewart, David

2006-01-01

.... In addition, the clinical trials that will be conducted in the VITAL Research Program will demonstrate the true rate of lung cancer recurrence and second primary tumor incidence in patients at high...

Vital Signs-Cervical Cancer is Preventable!

Centers for Disease Control (CDC) Podcasts

2014-11-05

This podcast is based on the November 2014 CDC Vital Signs report. Every visit to a doctor or nurse is an opportunity to prevent cervical cancer. Women can get a Pap test and HPV test to help prevent cervical cancer and adolescent boys and girls can get the HPV vaccination series to help prevent cervical and other cancers.  Created: 11/5/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 11/5/2014.

Vital Signs – Making Health Care Safer

Centers for Disease Control (CDC) Podcasts

This podcast is based on the March 2013 CDC Vital Signs report, which discusses lethal infections from carbapenem-resistant Enterobacteriaceae, or CRE, germs and ways health care providers can help stop CRE infections.

Why does the energy intensity of freight transport rise?

Energy Technology Data Exchange (ETDEWEB)

Scheele, D [Scientific Council for Government Policy (Netherlands)

1996-12-01

In advanced economies it is normal to observe declining energy intensities. Both improvements in conversion efficiency and in organisational efficiency of energy use cause energy demand to grow at a slower pace than the economy. In this context it is somewhat particular that in the vital sector of freight transport the energy intensity does not decline, but instead increases. The energy demand of this sector only takes a small share of the total energy demand. According to the World Energy Council the transport sector takes 30 percent of world energy demand and freight transport again takes 30 percent of the transport sector share, maritime transport excluded. Despite this small share some explanation is needed why the increase in energy demand form the volume growth of freight demand is not at least partly countered by a decline in the energy intensity. The purpose of this paper is to review some of the explanations that are given in the literature and to support these explanations with empirical evidence on the case of the Netherlands. (EG)

Home telemonitoring of vital signs--technical challenges and future directions.

Science.gov (United States)

Celler, Branko G; Sparks, Ross S

2015-01-01

The telemonitoring of vital signs from the home is an essential element of telehealth services for the management of patients with chronic conditions, such as congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), diabetes, or poorly controlled hypertension. Telehealth is now being deployed widely in both rural and urban settings, and in this paper, we discuss the contribution made by biomedical instrumentation, user interfaces, and automated risk stratification algorithms in developing a clinical diagnostic quality longitudinal health record at home. We identify technical challenges in the acquisition of high-quality biometric signals from unsupervised patients at home, identify new technical solutions and user interfaces, and propose new measurement modalities and signal processing techniques for increasing the quality and value of vital signs monitoring at home. We also discuss use of vital signs data for the automated risk stratification of patients, so that clinical resources can be targeted to those most at risk of unscheduled admission to hospital. New research is also proposed to integrate primary care, hospital, personal genomic, and telehealth electronic health records, and apply predictive analytics and data mining for enhancing clinical decision support.

Apexification in a non-vital tooth: By control of infection

Directory of Open Access Journals (Sweden)

Basgauda R Patil

2010-01-01

Full Text Available Endodontic management of immature non-vital permanent teeth in young pediatric patients is a great challenge to dentists. When the pulp of an incompletely formed tooth loses its vitality, then the entire root system has also lost its ability to continue to develop. The walls of the root canals are frequently divergent and open apices make debridement and obturation difficult. Thus, closure of the root apex is very essential for the success of endodontic treatment. Many different materials are used for the apexification procedure, for apical barrier formation and healing. However, in this present case the apical closure was achieved only by means of infection control.

Using linked data to evaluate motor vehicle crashes involving elderly drivers in Connecticut : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

Science.gov (United States)

1999-09-01

A deterministic algorithm was developed which allowed data from Department of Transportation motor vehicle crash records, state mortality registry records, and hospital admission and emergency department records to be linked for analysis of the impac...

Protection of swimming-induced oxidative stress in some vital ...

African Journals Online (AJOL)

Protection of swimming-induced oxidative stress in some vital organs by the treatment of composite extract of Withania somnifera, Ocimum sanctum and Zingiber officinalis in male rat. D Misra, B Maiti, D Ghosh ...

Vital Signs – Alcohol Screening and Counseling?

Centers for Disease Control (CDC) Podcasts

This podcast is based on the January 2014 CDC Vital Signs report. Millions of Americans drink too much, a dangerous behavior that can lead to serious health problems. Alcohol screening and counseling can help.

Comparison of vitality states of finishers and withdrawers in trail running: An enactive and phenomenological perspective.

Directory of Open Access Journals (Sweden)

Nadège Rochat

Full Text Available Studies on ultra-endurance suggest that during the races, athletes typically experience three vitality states (i.e., preservation, loss, and revival at the phenomenological level. Nevertheless, how these states contribute to the management and outcome of performance remains unclear. The aim of this study was to determine whether and how the vitality states experienced by runners and their evolution during a trail race can be used to distinguish finishers from withdrawers. From an enactive and phenomenological framework, we processed enactive interviews and blog posts of race narratives. We distinguished units of meaning, which were grouped into sequences of experience; each sequence was then categorized as one of the three vitality states: state of vitality preservation (SVP, state of vitality loss (SVL or state of vitality revival (SVR. We analyzed the distribution of these vitality states and their temporal organization at the beginning, in the second and third quarters, and at the end of the races, and we qualitatively characterized runners' adaptations to SVL. Results showed that finishers completed the race in SVP, with overall significantly more sequences in SVP and significantly fewer sequences in SVL than withdrawers. SVR did not discriminate finishers from withdrawers. The temporal organization of the vitality states showed a significant difference in the emergence of SVP from the second quarter of the race, as well as a significant difference in the emergence of SVL from the third quarter of the race. The analysis of adaptations to SVL confirmed that finishers were more capable of exiting SVL by enacting a preservation world when they felt physical or psychological alerts, whereas withdrawers remained in SVL. Our results showed that finishers and withdrawers did not enact the same phenomenological worlds in the race situation, especially in the organization of vitality adaptations and their relationships to difficulties; the cumulative

Wireless Communications in Smart Rail Transportation Systems

Directory of Open Access Journals (Sweden)

César Briso-Rodríguez

2017-01-01

Full Text Available Railway, subway, airplane, and other transportation systems have drawn an increasing interest on the use of wireless communications for critical and noncritical services to improve performance, reliability, and passengers experience. Smart transportation systems require the use of critical communications for operation and control, and wideband services can be provided using noncritical communications. High speed train (HST is one of the best test cases for the analysis of communication links and specification of the general requirements for train control and supervision, passenger communications, and onboard and infrastructure wireless sensors. In this paper, we analyze in detail critical and noncritical networks mainly using the HST as a test case. First, the different types of links for smart rail transportation are described, specifying the main requirements of the transportation systems, communications, and their applications for different services. Then, we propose a network architecture and requirements of the communication technologies for critical and noncritical data. Finally, an analysis is made for the future technologies, including the fifth-generation (5G communications, millimeter wave (mmWave, terahertz (THz, and satellites for critical and high-capacity communications in transportation.

Sustainable concretes for transportation infrastructure.

Science.gov (United States)

2010-07-01

performance in concrete for structural and transportation applications. Based on the challenges associated with coal ash (including SDA) and the economic costs linked to cement production, this research seeks to develop an environmentally friendly an...

CDC Signos Vitales: Enfermedad del legionario (CDC Vital Signs–Legionnaires’ Disease)

Centers for Disease Control (CDC) Podcasts

Este podcast se basa en la edición de junio del 2016 del informe Signos Vitales de los CDC. Las personas pueden contraer la enfermedad del legionario, un tipo grave de infección pulmonar, al inhalar pequeñas gotitas de agua contaminada con bacterias Legionella. Obtenga más información sobre lo que se puede hacer para ayudar a prevenir brotes de enfermedad del legionario y mantener seguras a las personas.

The characterization of novel mycorrhiza-specific phosphate transporters from ¤Lycopersicon esculentum¤ and ¤Solanum tuberosum¤ uncovers functional redundancy in symbiotic phosphate transport in solanaceous species

DEFF Research Database (Denmark)

Nagy, F.; Karandashov, V.; Chague, W.

2005-01-01

, is the transfer of phosphate (Pi) from the AM fungus to the plant, facilitated by plasma membrane-spanning Pi transporter proteins. The first mycorrhiza-specific plant Pi transporter to be identified, was StPT3 from potato [Nature 414 (2004) 462]. Here, we describe novel Pi transporters from the solanaceous...... species tomato, LePT4, and its orthologue StPT4 from potato, both being members of the Pht1 family of plant Pi transporters. Phylogenetic tree analysis demonstrates clustering of both LePT4 and StPT4 with the mycorrhiza-specific Pi transporter from Medicago truncatula [Plant Cell, 14 (2002) 2413] and rice......Solanaceous species are among the >200 000 plant species worldwide forming a mycorrhiza, that is, a root living in symbiosis with soil-borne arbuscular-mycorrhizal (AM) fungi. An important parameter of this symbiosis, which is vital for ecosystem productivity, agriculture, and horticulture...

Internet skills : vital assets in an information society

NARCIS (Netherlands)

van Deursen, Alexander Johannes Aloisius Maria

2010-01-01

Internet Skills, vital assets in an information society starts with a brief history of communication technologies. It appears that in the course of history, these technologies have changed and have put increasing demands on the people that use them. Moreover, the stakes for not being able to keep up

Ethnolinguistic Vitality among Japanese-Brazilians: Challenges and Possibilities

Science.gov (United States)

Sakamoto, Mitsuyo; Matsubara Morales, Leiko

2016-01-01

This paper explores ethnolinguistic vitality among Japanese-Brazilians ("Nikkeis"). First, an 18-item questionnaire was administered to 33 individuals who attended a seminar on bilingual studies held in São Paulo. Then, two bilingual "Nikkei" teachers who participated in the questionnaire and who grew up to be bilinguals…

CDC Vital Signs-Safer Food Saves Lives

Centers for Disease Control (CDC) Podcasts

2015-11-03

This podcast is based on the November 2015 CDC Vital Signs report. Contaminated food sent to several states can cause multistate outbreaks of foodborne illness and make a lot of people seriously ill. Learn what can be done to prevent and stop outbreaks.  Created: 11/3/2015 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 11/3/2015.

Vital Signs - Antibiotic RX in Hospitals: Proceed with Caution

Centers for Disease Control (CDC) Podcasts

This podcast is based on the March 2014 CDC Vital Signs report. Antibiotics save lives, but poor prescribing practices can put patients at risk for health problems. Learn how to protect patients by protecting antibiotics.

Vital affordances, occupying niches

DEFF Research Database (Denmark)

Dokumaci, Arseli

2017-01-01

This article proposes a new conceptual approach to disability and performance through a contribution that comes entirely from outside the disciplines; a re-theorisation of Gibson’s [1979. The Ecological Approach to Visual Perception. Hillsdale: Lawrence Erlbaum Associates] theory of affordances....... Drawing on three visual ethnographies with differently disabled individuals, and building upon my previous consideration of performance as ‘affordance creation’ in itself [Dokumaci, A. 2013. “On Falling Ill.” Performance Research 18 (4): 107–115], the article conceptualises affordances as a form of micro......-activism–one that can allow us to unpack the entanglements of disability, performance, and matter. Putting Gibson’s theory in conversation with Canguilhem’s philosophy of life, it proposes the concept ‘vital affordances’ as a new way to think through this micro-activism, and the way disabled individuals might transform...

Standardization of transportation classes for object-oriented deployment simulations.

Energy Technology Data Exchange (ETDEWEB)

Burke, J. F., Jr.; Howard, D. L.; Jackson, J.; Macal, C. M.; Nevins, M. R.; Van Groningen, C. N.

1999-07-30

Many recent efforts to integrate transportation and deployment simulations, although beneficial, have lacked a feature vital for seamless integration: a common data class representation. It is an objective of the Department of Defense (DoD) to standardize all classes used in object-oriented deployment simulations by developing a standard class attribute representation and behavior for all deployment simulations that rely on an underlying class representation. The Extensive Hierarchy and Object Representation for Transportation Simulations (EXHORT) is a collection of three hierarchies that together will constitute a standard and consistent class attribute representation and behavior that could be used directly by a large set of deployment simulations. The first hierarchy is the Transportation Class Hierarchy (TCH), which describes a significant portion of the defense transportation system; the other two deal with infrastructure and resource classes. EXHORT will allow deployment simulations to use the same set of underlying class data, ensure transparent exchanges, reduce the effort needed to integrate simulations, and permit a detailed analysis of the defense transportation system. This paper describes EXHORT's first hierarchy, the TCH, and provides a rationale for why it is a helpful tool for modeling major portions of the defense transportation system.

Estimating Pedestrian flows at train stations using the Station Transfer Model

NARCIS (Netherlands)

Van den Heuvel, J.P.A.; Dekkers, K.; De Vos, S.

2012-01-01

Train stations play a vital role in the door to door travel experience of train passengers. From the passengers’ value of time perspective, the station is the weakest link in total time value of the journey. Within the station the transfer function – moving between the various transport modes and

Still in the Fold

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

Afghanistan remains part of the U.S. grand plan for the region Afghanistan has long been a country of strategic importance, being a vital trade and transport link in Asia's heartland for centuries. Despite Afghanistan's currently appearing to be playing second fiddle to the tempestuous events in Iraq, the struggling coun-

Energy, fatigue, or both? A bifactor modeling approach to the conceptualization and measurement of vitality.

Science.gov (United States)

Deng, Nina; Guyer, Rick; Ware, John E

2015-01-01

Vitality is an important domain reflecting both the physical and emotional components of health-related quality of life. Because of its complexity, it has been defined and measured both broadly and narrowly. We explored the dimensionality of a very comprehensive item bank hypothesized to measure vitality and its related concepts. Secondary analyses were conducted using the responses of 1,343 adults representative of the US general population to Internet-based surveys including 42 items compiled from multiple scales (e.g., SF-36 Vitality, PROMIS-Fatigue), covering a broad range of vitality-related content areas (energy, fatigue, and their interference with physical, mental, social activities, and quality of life). Exploratory and confirmatory factor models were evaluated independently using split-half samples. Bifactor model was used to assess the essential unidimensionality of the items, in comparison with traditional unidimensional, multidimensional, and hierarchical models. Method effects of a common scale or phrase were modeled via correlating errors. The exploratory factor analysis identified one dominant factor. The confirmatory factor analysis identified a best-fitting (CFI = 0.964, RMSEA = 0.084) bifactor model with one general (vitality) and two group (energy and fatigue) factors, explaining 69, 3, and 4 % of total variance. Correlating errors accounting for the method effects were important in identifying the substantive dimensionality of the items. The bifactor model proved to be useful for evaluating the dimensionality of a complex construct. Results supported conceptualizing and measuring vitality as a unidimensional energy-fatigue construct. We encourage future studies comparing practical implications of measures based on the broader and narrower conceptualizations of vitality.

A systems approach to risk reduction of transportation infrastructure networks subject to multiple hazards : final report, December 31, 2008.

Science.gov (United States)

2008-12-31

Integrity, robustness, reliability, and resiliency of infrastructure networks are vital to the economy, : security and well-being of any country. Faced with threats caused by natural and man-made hazards, : transportation infrastructure network manag...

Air transport system

CERN Document Server

Schmitt, Dieter

2016-01-01

The book addresses all major aspects to be considered for the design and operation of aircrafts within the entire transportation chain. It provides the basic information about the legal environment, which defines the basic requirements for aircraft design and aircraft operation. The interactions between  airport, air traffic management and the airlines are described. The market forecast methods and the aircraft development process are explained to understand the very complex and risky business of an aircraft manufacturer. The principles of flight physics as basis for aircraft design are presented and linked to the operational and legal aspects of air transport including all environmental impacts. The book is written for graduate students as well as for engineers and experts, who are working in aerospace industry, at airports or in the domain of transport and logistics.

Cardiac glycoside activities link Na(+)/K(+) ATPase ion-transport to breast cancer cell migration via correlative SAR.

Science.gov (United States)

Magpusao, Anniefer N; Omolloh, George; Johnson, Joshua; Gascón, José; Peczuh, Mark W; Fenteany, Gabriel

2015-02-20

The cardiac glycosides ouabain and digitoxin, established Na(+)/K(+) ATPase inhibitors, were found to inhibit MDA-MB-231 breast cancer cell migration through an unbiased chemical genetics screen for cell motility. The Na(+)/K(+) ATPase acts both as an ion-transporter and as a receptor for cardiac glycosides. To delineate which function is related to breast cancer cell migration, structure-activity relationship (SAR) profiles of cardiac glycosides were established at the cellular (cell migration inhibition), molecular (Na(+)/K(+) ATPase inhibition), and atomic (computational docking) levels. The SAR of cardiac glycosides and their analogs revealed a similar profile, a decrease in potency when the parent cardiac glycoside structure was modified, for each activity investigated. Since assays were done at the cellular, molecular, and atomic levels, correlation of SAR profiles across these multiple assays established links between cellular activity and specific protein-small molecule interactions. The observed antimigratory effects in breast cancer cells are directly related to the inhibition of Na(+)/K(+) transport. Specifically, the orientation of cardiac glycosides at the putative cation permeation path formed by transmembrane helices αM1-M6 correlates with the Na(+) pump activity and cell migration. Other Na(+)/K(+) ATPase inhibitors that are structurally distinct from cardiac glycosides also exhibit antimigratory activity, corroborating the conclusion that the antiport function of Na(+)/K(+) ATPase and not the receptor function is important for supporting the motility of MDA-MB-231 breast cancer cells. Correlative SAR can establish new relationships between specific biochemical functions and higher-level cellular processes, particularly for proteins with multiple functions and small molecules with unknown or various modes of action.

CDC Vital Signs–Opioid Prescribing

Centers for Disease Control (CDC) Podcasts

2017-07-06

This podcast is based on the July 2017 CDC Vital Signs report. Higher opioid prescribing puts patients at risk for addiction and overdose. Learn what can be done about this serious problem.  Created: 7/6/2017 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/6/2017.

Vitality at work and its associations with lifestyle, self-determination, organizational culture, and with employees' performance and sustainable employability

NARCIS (Netherlands)

van Scheppingen, A.R.; de Vroome, E.M.M.; ten Have, K.C.J.M.; Zwetsloot, G.I.J.M.; Wiezer, N.; van Mechelen, W.

2015-01-01

BACKGROUND: Vitality at work is an important factor for optimal functioning and sustainable employability. To date, knowledge on how to promote vitality at work is fragmented. OBJECTIVE: Contribute to knowledge on how to promote vitality at work. METHODS: Determinants of vitality at work are

An assessment of transportation issues under exceptional conditions : the case of the mass media and the Northridge Earthquake

Science.gov (United States)

1998-05-01

This study explores how the mass media covered transportation issues following the 1994 Northridge earthquake. The mass media were a vital channel for travel information, and they provided considerable information to the public about the safety of tr...

Through-Wall Multiple Targets Vital Signs Tracking Based on VMD Algorithm

Directory of Open Access Journals (Sweden)

Jiaming Yan

2016-08-01

Full Text Available Targets located at the same distance are easily neglected in most through-wall multiple targets detecting applications which use the single-input single-output (SISO ultra-wideband (UWB radar system. In this paper, a novel multiple targets vital signs tracking algorithm for through-wall detection using SISO UWB radar has been proposed. Taking advantage of the high-resolution decomposition of the Variational Mode Decomposition (VMD based algorithm, the respiration signals of different targets can be decomposed into different sub-signals, and then, we can track the time-varying respiration signals accurately when human targets located in the same distance. Intensive evaluation has been conducted to show the effectiveness of our scheme with a 0.15 m thick concrete brick wall. Constant, piecewise-constant and time-varying vital signs could be separated and tracked successfully with the proposed VMD based algorithm for two targets, even up to three targets. For the multiple targets’ vital signs tracking issues like urban search and rescue missions, our algorithm has superior capability in most detection applications.

A Mechanistic Link from GABA to Cortical Architecture and Perception.

Science.gov (United States)

Kolasinski, James; Logan, John P; Hinson, Emily L; Manners, Daniel; Divanbeighi Zand, Amir P; Makin, Tamar R; Emir, Uzay E; Stagg, Charlotte J

2017-06-05

Understanding both the organization of the human cortex and its relation to the performance of distinct functions is fundamental in neuroscience. The primary sensory cortices display topographic organization, whereby receptive fields follow a characteristic pattern, from tonotopy to retinotopy to somatotopy [1]. GABAergic signaling is vital to the maintenance of cortical receptive fields [2]; however, it is unclear how this fine-grain inhibition relates to measurable patterns of perception [3, 4]. Based on perceptual changes following perturbation of the GABAergic system, it is conceivable that the resting level of cortical GABAergic tone directly relates to the spatial specificity of activation in response to a given input [5-7]. The specificity of cortical activation can be considered in terms of cortical tuning: greater cortical tuning yields more localized recruitment of cortical territory in response to a given input. We applied a combination of fMRI, MR spectroscopy, and psychophysics to substantiate the link between the cortical neurochemical milieu, the tuning of cortical activity, and variability in perceptual acuity, using human somatosensory cortex as a model. We provide data that explain human perceptual acuity in terms of both the underlying cellular and metabolic processes. Specifically, higher concentrations of sensorimotor GABA are associated with more selective cortical tuning, which in turn is associated with enhanced perception. These results show anatomical and neurochemical specificity and are replicated in an independent cohort. The mechanistic link from neurochemistry to perception provides a vital step in understanding population variability in sensory behavior, informing metabolic therapeutic interventions to restore perceptual abilities clinically. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Herpes viruses, cytokines, and altered hemostasis in vital exhaustion.

NARCIS (Netherlands)

Ven, A.J.A.M. van der; Diest, R. van; Hamulyak, K.; Maes, M.; Bruggeman, C.A.; Appels, A.

2003-01-01

OBJECTIVE: Infections with herpes viruses have been implicated in the pathogenesis of atherosclerosis. We tested the hypothesis that vital exhaustion (VE) is associated with multiple herpesvirus infections, such as herpes simplex virus, varicella-zoster virus, Epstein-Barr virus, and

Can Sophie's choice be adequately captured by cold computation of minimizing losses? An fMRI study of vital loss decisions.

Directory of Open Access Journals (Sweden)

Qi Li

Full Text Available The vast majority of decision-making research is performed under the assumption of the value maximizing principle. This principle implies that when making decisions, individuals try to optimize outcomes on the basis of cold mathematical equations. However, decisions are emotion-laden rather than cool and analytic when they tap into life-threatening considerations. Using functional magnetic resonance imaging (fMRI, this study investigated the neural mechanisms underlying vital loss decisions. Participants were asked to make a forced choice between two losses across three conditions: both losses are trivial (trivial-trivial, both losses are vital (vital-vital, or one loss is trivial and the other is vital (vital-trivial. Our results revealed that the amygdala was more active and correlated positively with self-reported negative emotion associated with choice during vital-vital loss decisions, when compared to trivial-trivial loss decisions. The rostral anterior cingulate cortex was also more active and correlated positively with self-reported difficulty of choice during vital-vital loss decisions. Compared to the activity observed during trivial-trivial loss decisions, the orbitofrontal cortex and ventral striatum were more active and correlated positively with self-reported positive emotion of choice during vital-trivial loss decisions. Our findings suggest that vital loss decisions involve emotions and cannot be adequately captured by cold computation of minimizing losses. This research will shed light on how people make vital loss decisions.

The eyes, ears and collective voice for nuclear transport

International Nuclear Information System (INIS)

Green, L.

2000-01-01

Transport is a vital part of the nuclear industry and the safety record of radioactive materials transport across the world is excellent. This record is due primarily to well-founded regulations developed by such intergovernmental organisations as the International Atomic Energy Agency and the International Maritime Organisation. It is due, also, to the professionalism of those in the industry. Attitudes to nuclear transport are important. They have the potential, if not heeded, and not responded to sensitively and convincingly to make life very much more difficult for those committed to the safe, reliable and efficient transport of nuclear materials. What is required is a balanced situation, which takes account both of the public's attitudes and industry's need for an efficient operation. The voices of the nuclear transport industry and those who value the industry need to be heard. The World Nuclear Transport Institute was established to provide the nuclear transport industry with the collective eyes, ears and voice in the key intergovernmental organisations which are so important to it. The nuclear transport industry has a safety record which could be regarded as a model for the transport of dangerous goods of all kinds. The industry is situated within a comprehensive and strict regime of national and international standards and regulations. That is the message to be disseminated, and that is the commitment of the World Nuclear Transport Institute as it works to protect and to promote the safe, efficient and reliable transport of radioactive materials. (author)

Usage of link-level performance indicators for HSDPA network-level simulations in E-UMTS

NARCIS (Netherlands)

Brouwer, Frank; de Bruin, I.C.C.; Silva, João Carlos; Souto, Nuno; Cercas, Francisco; Correia, Américo

2004-01-01

The paper describes integration of HSDPA (high-speed downlink packet access) link-level simulation results into network-level simulations for enhanced UMTS. The link-level simulations model all physical layer features depicted in the 3GPP standards. These include: generation of transport blocks;

Integration and embedding of vital signs sensors and other devices into textiles

OpenAIRE

Abreu, Maria José Araújo Marques; Carvalho, Helder; Catarino, André P.; Rocha, A. M.

2010-01-01

The development of ubiquitous vital sign monitoring has become a very up-to-date research theme for many academics and industrial companies in the last years. With new materials and integration techniques, it is possible to implement vital sign monitoring in an economic manner, directly into textile products. This unobtrusive presence of sensors is especially important for the monitoring of children or elderly people. This paper focuses on two aspects of sensor integration: Integration of off...

The Role of Transport Activities in Logistics Chain

OpenAIRE

Robert Chira

2014-01-01

The operation of transportation determines the efficiency of moving products. The progress in techniques and management principles improves the moving load, delivery speed, service quality, operation costs, the usage of facilities and energy saving. Transportation takes a crucial part in the manipulation of logistic. Reviewing the current condition, a strong system needs a clear frame of logistics and a proper transport implements and techniques to link the producing procedures. The objective...

Subjective Vitality and Patterns of Acculturation: Four Cases

Science.gov (United States)

Ehala, Martin; Vedernikova, Elena

2015-01-01

The article presents a comparative analysis of the subjective vitalities (SVs) of the minority groups of Latvia (Russian-speakers), Lithuania (Russian-speakers and Poles) and Mari El (Maris) in the Russian Federation, with a particular focus on the Mari case. The same extended version of the SV questionnaire was used in quantitative surveys in all…

Ten Indicators of Vitality in Smaller Academic Libraries

Science.gov (United States)

Pappas, David

2009-01-01

This paper provides a means of quickly ascertaining the relative health of smaller academic libraries by presenting a top ten list of vitality indicators. The list is based on an observational convenience sampling of thirty smaller academic libraries across the United States. The indicators making the list were those which appeared most often in…

Nursing assessment of continuous vital sign surveillance to improve patient safety on the medical/surgical unit.

Science.gov (United States)

Watkins, Terri; Whisman, Lynn; Booker, Pamela

2016-01-01

Evaluate continuous vital sign surveillance as a tool to improve patient safety in the medical/surgical unit. Failure-to-rescue is an important measure of hospital quality. Patient deterioration is often preceded by changes in vital signs. However, continuous multi-parameter vital sign monitoring may decrease patient safety with an abundance of unnecessary alarms. Prospective observational study at two geographically disperse hospitals in a single hospital system. A multi-parameter vital sign monitoring system was installed in a medical/surgical unit in Utah and one in Alabama providing continuous display of SpO2, heart rate, blood pressure and respiration rate on a central station. Alarm thresholds and time to alert annunciations were set based on prior analysis of the distribution of each vital sign. At the end of 4 weeks, nurses completed a survey on their experience. An average alert per patient, per day was determined retrospectively from the saved vital signs data and knowledge of the alarm settings. Ninety-two per cent of the nurses agreed that the number of alarms and alerts were appropriate; 54% strongly agreed. On average, both units experienced 10·8 alarms per patient, per day. One hundred per cent agreed the monitor provided valuable patient data that increased patient safety; 79% strongly agreed. Continuous, multi-parameter patient monitoring could be performed on medical/surgical units with a small and appropriate level of alarms. Continuous vital sign assessment may have initiated nursing interventions that prevented failure-to-rescue events. Nurses surveyed unanimously agreed that continuous vital sign surveillance will help enhance patient safety. Nursing response to abnormal vital signs is one of the most important levers in patient safety, by providing timely recognition of early clinical deterioration. This occurs through diligent nursing surveillance, involving assessment, interpretation of data, recognition of a problem and meaningful

LongoVital i forebyggelsen af recidiverende aftøs stomatit. 1

DEFF Research Database (Denmark)

Pedersen, A; Hougen, H P; Klausen, B

1991-01-01

LongoVital (LV) (DK. reg. no. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during daily intake of LV for six months as compared with placebo in a double-blind, rando......LongoVital (LV) (DK. reg. no. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during daily intake of LV for six months as compared with placebo in a double...

Loss of Olfactory Function and Nutritional Status in Vital Older Adults and Geriatric Patients

NARCIS (Netherlands)

Toussaint, N.; Roon, de M.; Campen, van J.P.C.M.; Kremer, S.; Boesveldt, S.

2015-01-01

The aim of this cross-sectional study was to assess the association of olfactory function and nutritional status in vital older adults and geriatric patients. Three hundred forty-five vital (mean age 67.1 years) and 138 geriatric older adults (mean age 80.9 years) were included. Nutritional status

Associations between VO2max and vitality in older workers: A cross-sectional study

NARCIS (Netherlands)

Strijk, J.E.; Proper, K.I.; Klaver, L.; Beek, A.J. van der; Mechelen, W. van

2010-01-01

Background. To prevent early exit from work, it is important to study which factors contribute to healthy ageing. One concept that is assumed to be closely related to, and therefore may influence healthy ageing, is vitality. Vitality consists of both a mental and a physical component, and is

Modeling Water and Nutrient Transport through the Soil-Root-Canopy Continuum: Explicitly Linking the Below- and Above-Ground Processes

Science.gov (United States)

Kumar, P.; Quijano, J. C.; Drewry, D.

2010-12-01

Vegetation roots provide a fundamental link between the below ground water and nutrient dynamics and above ground canopy processes such as photosynthesis, evapotranspiration and energy balance. The “hydraulic architecture” of roots, consisting of the structural organization of the root system and the flow properties of the conduits (xylem) as well as interfaces with the soil and the above ground canopy, affect stomatal conductance thereby directly linking them to the transpiration. Roots serve as preferential pathways for the movement of moisture from wet to dry soil layers during the night, both from upper soil layer to deeper layers during the wet season (‘hydraulic descent’) and vice-versa (‘hydraulic lift’) as determined by the moisture gradients. The conductivities of transport through the root system are significantly, often orders of magnitude, larger than that of the surrounding soil resulting in movement of soil-moisture at rates that are substantially larger than that through the soil. This phenomenon is called hydraulic redistribution (HR). The ability of the deep-rooted vegetation to “bank” the water through hydraulic descent during wet periods for utilization during dry periods provides them with a competitive advantage. However, during periods of hydraulic lift these deep-rooted trees may facilitate the growth of understory vegetation where the understory scavenges the hydraulically lifted soil water. In other words, understory vegetation with relatively shallow root systems have access to the banked deep-water reservoir. These inter-dependent root systems have a significant influence on water cycle and ecosystem productivity. HR induced available moisture may support rhizosphere microbial and mycorrhizal fungi activities and enable utilization of heterogeneously distributed water and nutrient resources To capture this complex inter-dependent nutrient and water transport through the soil-root-canopy continuum we present modeling

CDC Vital Signs: Adult Seat Belt Use in the US

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

IO-Link Wireless enhanced factory automation communication for Industry 4.0 applications

Directory of Open Access Journals (Sweden)

R. Heynicke

2018-03-01

Full Text Available In the context of the Industry 4.0 initiative, Cyber-Physical Production Systems (CPPS or Cyber Manufacturing Systems (CMS can be characterized as advanced networked mechatronic production systems gaining their added value by interaction with the ambient Industrial Internet of Things (IIoT. In this context appropriate communication technologies and standards play a vital role to realize the manifold potential improvements in the production process. One of these standards is IO-Link. In 2016 more than 5 million IO-Link nodes have been produced and delivered, still gaining increasing acceptance for the communication between sensors, actuators and the control level. The steadily increasing demand for more flexibility in automation solutions can be fulfilled using wireless technologies. With the wireless extension for the IO-Link standard, which will be presented in this article, maximum cycle times of 5 ms can be achieved with a probability that this limit will be exceeded to be at maximum one part per billion. Also roaming capabilities, wireless coexistence mechanisms and the possibility to include battery-powered or energy-harvesting sensors with very limited energy resources in the realtime network were defined. For system planning, setup, operation and maintenance, the standard engineering tools of IO-Link can be employed so that the backward compatibility with wired IO-Link solutions can be guaranteed. Interoperability between manufacturers is a key requirement for any communication standard, thus a procedure for IO-Link Wireless testing is also suggested.

Vital Signs-Preventing Pregnancy in Younger Teens

Centers for Disease Control (CDC) Podcasts

2014-04-08

This podcast is based on the April 2014 CDC Vital Signs report. Births to teens are declining, still, in 2012, more than 86,000 teens ages 15 to 17 gave birth. This program discusses what health care providers, parents, and teens can do to help prevent teen pregnancy.  Created: 4/8/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/8/2014.

Vital Signs-Children Need More Fruits and Vegetables!

Centers for Disease Control (CDC) Podcasts

2014-08-05

This podcast is based on the August 2014 CDC Vital Signs report. Children in the U.S. aren't eating enough fruits and vegetables. Learn what you can do to impact this problem.  Created: 8/5/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 8/5/2014.

CDC Vital Signs-Protect Patients from Antibiotic Resistance

Centers for Disease Control (CDC) Podcasts

2016-03-03

This podcast is based on the March 2016 CDC Vital Signs report. Patients can get serious healthcare-associated infections, or HAIs, while receiving medical treatment in a healthcare facility. Learn how to prevent healthcare-associated infections.  Created: 3/3/2016 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 3/3/2016.

Small substrate transport and mechanism of a molybdate ATP binding cassette transporter in a lipid environment.

Science.gov (United States)

Rice, Austin J; Harrison, Alistair; Alvarez, Frances J D; Davidson, Amy L; Pinkett, Heather W

2014-05-23

Embedded in the plasma membrane of all bacteria, ATP binding cassette (ABC) importers facilitate the uptake of several vital nutrients and cofactors. The ABC transporter, MolBC-A, imports molybdate by passing substrate from the binding protein MolA to a membrane-spanning translocation pathway of MolB. To understand the mechanism of transport in the biological membrane as a whole, the effects of the lipid bilayer on transport needed to be addressed. Continuous wave-electron paramagnetic resonance and in vivo molybdate uptake studies were used to test the impact of the lipid environment on the mechanism and function of MolBC-A. Working with the bacterium Haemophilus influenzae, we found that MolBC-A functions as a low affinity molybdate transporter in its native environment. In periods of high extracellular molybdate concentration, H. influenzae makes use of parallel molybdate transport systems (MolBC-A and ModBC-A) to take up a greater amount of molybdate than a strain with ModBC-A alone. In addition, the movement of the translocation pathway in response to nucleotide binding and hydrolysis in a lipid environment is conserved when compared with in-detergent analysis. However, electron paramagnetic resonance spectroscopy indicates that a lipid environment restricts the flexibility of the MolBC translocation pathway. By combining continuous wave-electron paramagnetic resonance spectroscopy and substrate uptake studies, we reveal details of molybdate transport and the logistics of uptake systems that employ multiple transporters for the same substrate, offering insight into the mechanisms of nutrient uptake in bacteria. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

Predicting subjective vitality and performance in sports: the role of passion and achievement goals.

Science.gov (United States)

Li, Chiung-Huang

2010-06-01

The major purpose of this study was to test the hypothesized paths from dualistic passions through achievement goals to subjective vitality and performance in sports. 645 high school athletes participated. The proposed structural equation model, with relationships between dualistic passions and subjective vitality and sports performance mediated by achievement goals, fit the data well, especially for mastery-approach and performance-approach goals. Harmonious and obsessive passions may lead athletes to high performance via the adoption of mastery-approach goals. However, these passions seem to have two paths influencing personal functioning: direct effects make players feel energetic, and indirect effects on subjective vitality through adoption of mastery-approach and performance-approach goals.

The Relationship between Faculty Involvement in Governance and Faculty Vitality: The Case of North Carolina Community Colleges

Science.gov (United States)

Madray, Van

2009-01-01

This study examines the effects of governance involvement on the vitality of community college faculty members. This study explores the degree to which involvement in the governance of a college through a faculty senate fosters the vitality of elected faculty members. While faculty vitality is a difficult concept to measure directly, faculty…

Signos Vitales de los CDC Cómo prevenir los brotes de norovirus (Vital Signs-Preventing Norovirus Outbreaks)

Centers for Disease Control (CDC) Podcasts

2014-06-03

Este podcast se basa en la edición de junio del 2014 del informe Signos Vitales de los CDC. Los norovirus infectan cada año a cerca de 20 millones de personas en los Estados Unidos. Sepa cómo protegerse y proteger a su familia de esta enfermedad que es muy contagiosa y potencialmente grave.  Created: 6/3/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 6/3/2014.

Examining the Relationship between Self-rumination and Happiness: The Mediating and Moderating Role of Subjective Vitality

OpenAIRE

SARIÇAM, Hakan

2016-01-01

The basic purpose of this study is to examine the mediating and moderating role of subjective vitality in relationship between rumination and subjective happiness. The participants were 420 university students. In this research, the Self-rumination Scale-SRS, the Subjective Vitality Scale and the Short Form of Oxford Happiness Questionnaire were used. The relationships between rumination, subjective vitality, and happiness were examined using correlation analysis and hierarchical regression a...

A new biomedical device for in vivo multiparametric evaluation of tissue vitality in critical care medicine

Science.gov (United States)

Mayevsky, Avraham; Deutsch, Assaf; Dekel, Nava; Pevzner, Eliyahu; Jaronkin, Alex

2005-04-01

Real time Monitoring of mitochondrial function in vivo is a significant factor in the understanding of tissue vitality. Nevertheless a single parameter monitoring device is not appropriate and effective in clinical diagnosis of tissue vitality. Therefore we have developed a multi-parametric monitoring system that monitors, in addition to mitochondrial NADH redox state, tissue microcirculatory blood flow, tissue total back-scattered light as an indication of blood volume and blood oxygenation (Hb02). In the present communication a new device named "CritiView" is described. This device was developed in order to enable real time monitoring of the four parameters from various organs in the body. The main medical application of the CritiView is in critical care medicine of patients hospitalized in the Intensive Care Units (ICUs) and intraoperatively in operating rooms. The physiological basis for our clinical monitoring approach is based on the well known response to the development of body emergency situation, such as shock or trauma. Under such conditions a process of blood flow redistribution will give preference to vital organs (Brain, Heart) neglecting less vital organs (Skin, G-I tract or the urinary system). Under such condition the brain will by hyperperfused and O2 supply will increase to provide the need of the activated mitochondria. The non-vital organs will be hypoperfused and mitochondial function will be inhibited leading to energy failure. This differentiation between the two types of organs could be used for the early detection of body deterioration by monitoring of the non-vital organ vitality. A fiber optic sensor was embedded in a Foley catheter, enabling the monitoring of Urethral wall vitality, to serve as an early warning signal of body deterioration.

Using linked data to evaluate medical and financial outcomes of motor vehicle crashes in Connecticut : Crash Outcome Data Evaluation System (CODES) linked data demonstration project

Science.gov (United States)

1999-09-01

A deterministic algorithm was developed which allowed data from Department of Transportation motor vehicle crash records, state mortality registry records, and hospital admission and emergency department records to be linked for analysis of the finan...

Should academic journals publish e-cigarette research linked to tobacco companies?

Science.gov (United States)

Shaw, David M; Etter, Jean-François; Elger, Bernice S

2016-08-01

Electronic cigarettes are currently polarizing professional opinion. Some public health experts regard them as an effective smoking cessation aid and a vital means of reducing active and passive smoking, while others regard them as another attempt by the tobacco industry to create new customers and addicts. These different attitudes unsurprisingly yield different conclusions regarding both the appropriate regulation of e-cigarettes and the ethical status of research funded by, or conducted in, cooperation with the tobacco industry. This paper examines whether e-cigarette research linked to the tobacco industry should be regarded as an exception to the rule that tobacco industry research is so tainted by conflicts of interest that journals should refuse to publish them, or at the very least treat them as a special case for scrutiny. Despite the fact that e-cigarettes can be used for smoking cessation, most of the conflicts of interest that apply to other tobacco research also apply to e-cigarette research linked to that industry. Journals that currently refuse to publish findings from studies linked to tobacco companies have no reason to make an exception in the case of e-cigarettes. © 2015 Society for the Study of Addiction.

Evaluation of high-standard public transport centres in the Slovak Republic

Directory of Open Access Journals (Sweden)

Horňák Marcel

2015-12-01

Full Text Available Despite of increasing volumes of individual passenger transport and growing dependence of the post-socialist societies on the passenger car, public transport is still inevitable for certain communities. Its social and environmental aspects are obvious reasons why public transport remains within the scope of state and regional policies as a mixture of public and commercial services. Long-distance and international overground public transport represents a higher standard of travelling of considerably commercial nature. An important feature of this segment of the public transport is its capability to compete with individual transportation for long-distance journeys. The commercial character of the long-distance public transport should motivate operators to run territorially effective links covering adequately populated communites and regions with high demand for this segment of public-transport services. This study deals with several territorial aspects of the network of long-distance and international bus and train links of public transport in the Slovak Republic. The network of communities having direct access to the high-standard modes of public transport has been identified, revealing some of their spatial patterns and focusing on categorization of urban settlements by selected parameters of high-standard public transport services. The relationship with the population size of the urban settlements is assessed in the study, too.

Effectiveness of a Multilevel Workplace Health Promotion Program on Vitality, Health, and Work-Related Outcomes.

Science.gov (United States)

Hendriksen, Ingrid J M; Snoijer, Mirjam; de Kok, Brenda P H; van Vilsteren, Jeroen; Hofstetter, Hedwig

2016-06-01

Evaluation of the effectiveness of a workplace health promotion program on employees' vitality, health, and work-related outcomes, and exploring the influence of organizational support and the supervisors' role on these outcomes. The 5-month intervention included activities at management, team, and individual level targeting self-management to perform healthy behaviors: a kick-off session, vitality training sessions, workshops, individual coaching, and intervision. Outcome measures were collected using questionnaires, health checks, and sickness absence data at baseline, after the intervention and at 10 months follow-up. For analysis linear and generalized mixed models were used. Vitality, work performance, sickness absence, and self-management significantly improved. Good organizational support and involved supervisors were significantly associated with lower sickness absence. Including all organizational levels and focusing on increasing self-management provided promising results for improving vitality, health, and work-related outcomes.

Critical infrastructures risk and vulnerability assessment in transportation of dangerous goods transportation by road and rail

CERN Document Server

Vamanu, Bogdan I; Katina, Polinpapilinho F

2016-01-01

This book addresses a key issue in today’s society: the safer transport of dangerous goods, taking into account people, the environment and economics. In particular, it offers a potential approach to identifying the issues, developing the models, providing the methods and recommending the tools to address the risks and vulnerabilities involved. We believe this can only be achieved by assessing those risks in a comprehensive, quantifiable and integrated manner. Examining both rail and road transportation, the book is divided into three sections, covering: the mature and accepted (by both academia and practitioners) methodology of risk assessment; the vulnerability assessment – a novel approach proposed as a vital complement to risk; guidance and support to build the tools that make methods and equations to yield: the Decision Support Systems. Throughout the book, the authors do not endeavor to provide THE solution. Instead, the book offers insightful food for thought for students, researchers, practitioner...

An experimental vital signs detection radar using low-IF heterodyne architecture and single-sideband transmission

DEFF Research Database (Denmark)

Jensen, Brian Sveistrup; Johansen, Tom Keinicke; Yan, Lei

2013-01-01

In this paper an experimental X-band radar system, called DTU-VISDAM, developed for the detection and monitoring of human vital signs is described. The DTU-VISDAM radar exploits a low intermediate frequency (IF) heterodyne RF front-end architecture and single-sideband (SSB) transmission for easier...... and more reliable extraction of the vital signs. The hardware implementation of the proposed low-IF RF front-end architecture and associated IF circuitry is discussed. Furthermore, the signal processing and calibration steps necessary to extract the vital signs information measured on a human subject...

Mechanistic logic underlying the axonal transport of cytosolic proteins

Science.gov (United States)

Scott, David A.; Das, Utpal; Tang, Yong; Roy, Subhojit

2011-01-01

Proteins vital to presynaptic function are synthesized in the neuronal perikarya and delivered into synapses via two modes of axonal transport. While membrane-anchoring proteins are conveyed in fast axonal transport via motor-driven vesicles, cytosolic proteins travel in slow axonal transport; via mechanisms that are poorly understood. We found that in cultured axons, populations of cytosolic proteins tagged to photoactivable-GFP (PA-GFP) move with a slow motor-dependent anterograde bias; distinct from vesicular-trafficking or diffusion of untagged PA-GFP. The overall bias is likely generated by an intricate particle-kinetics involving transient assembly and short-range vectorial spurts. In-vivo biochemical studies reveal that cytosolic proteins are organized into higher-order structures within axon-enriched fractions that are largely segregated from vesicles. Data-driven biophysical modeling best predicts a scenario where soluble molecules dynamically assemble into mobile supra-molecular structures. We propose a model where cytosolic proteins are transported by dynamically assembling into multi-protein complexes that are directly/indirectly conveyed by motors. PMID:21555071

Vital Signs – When Food Bites Back

Centers for Disease Control (CDC) Podcasts

This podcast is based on the June 2013 CDC Vital Signs report. It discusses food poisoning and specifically, Listeria. If you're 65 or older, have a weakened immune system, or are pregnant, you must be especially careful when selecting, preparing, and storing food.

In Search of Vitality

DEFF Research Database (Denmark)

Jørgensen, Jens Lohfert; Ebbesen Nielsen, Louise

2010-01-01

This article draws attention to the paradigmatic shift in the use of the concept of ‘life’, which can be observed at the end of the nineteenth century. With Michel Foucault’s notion of bio-power as a foil, the article aims firstly to discuss how influential aesthetic, biological and political...... concepts such as vitalism (Hans Driesch) and degeneration (Max Nordau) can be conceived as different reactions to Charles Darwin’s On the Origin of the Species in the light of bio-power. Even though both Driesch and Nordau use Darwin’s theories to produce positive ideas about respectively the strong...... and healthy body and the strong and healthy society, it is important to note that they do not converge. Secondly, the article aims to discuss how a controversy between these concepts is given literary form in the Danish author Herman Bang’s novel Hopeless Generations (1880), perceived as one of the first...

La teoria del ciclo vitale del risparmio di Modigliani cinquant’anni dopo

Directory of Open Access Journals (Sweden)

Mauro Baranzini

2012-04-01

Full Text Available In the early 50s Franco Modigliani and Richard Brumberg and Albert Ando, ​​formulated the life-cycle theory of consumption and saving, which has been a huge success and undisputed for at least three decades. However, since the early 80s the life-cycle theory has been criticized in an increasingly tight for at least four reasons. The first is the existence of a significant intergenerational transmission of wealth, due to factors exogenous to the model of the life cycle. The second reason is the increasing evidence that the rich continue to save a greater extent than the less fortunate, as, in fact, Keynes argued. The third reason is that there is increasing evidence, at least in Western Europe and Japan, young families, during twenty and thirty years of age, save a positive and growing share of their income, which arises in decided contrast to the original version of the life-cycle theory. Finally, a number of empirical studies have found that retirees dismiss a high proportion of their income. This requires a serious rethinking of the approach of the life-cycle theory, which affects both the economic analysis and economic policy. Nei primi anni ’50 Franco Modigliani, insieme a Richard Brumberg e ad Albert Ando, formulò la teoria del ciclo vitale del consumo e del risparmio, che ha riscosso un enorme e indiscusso successo per almeno tre decenni. Tuttavia, a partire dai primi anni ’80 la teoria del ciclo vitale è stata criticata in modo sempre più serrato, per almeno quattro ragioni. La prima consiste nell’esistenza di una significativa trasmissione intergenerazionale della ricchezza, da ricondurre a cause esogene al modello del ciclo vitale. La seconda ragione è rappresentata dalla crescente evidenza che i ricchi continuano a risparmiare in misura maggiore rispetto ai meno fortunati, come, in effetti, Keynes sosteneva. Il terzo motivo è che vi sono prove sempre più evidenti, almeno nell’Europa occidentale e in Giappone

National Vital Statistics System (NVSS) - National Cardiovascular Disease Surveillance Data

Data.gov (United States)

U.S. Department of Health & Human Services — 2000 forward. NVSS is a secure, web-based data management system that collects and disseminates the Nation's official vital statistics. Indicators from this data...

Mixed Transportation Network Design under a Sustainable Development Perspective

Directory of Open Access Journals (Sweden)

Jin Qin

2013-01-01

Full Text Available A mixed transportation network design problem considering sustainable development was studied in this paper. Based on the discretization of continuous link-grade decision variables, a bilevel programming model was proposed to describe the problem, in which sustainability factors, including vehicle exhaust emissions, land-use scale, link load, and financial budget, are considered. The objective of the model is to minimize the total amount of resources exploited under the premise of meeting all the construction goals. A heuristic algorithm, which combined the simulated annealing and path-based gradient projection algorithm, was developed to solve the model. The numerical example shows that the transportation network optimized with the method above not only significantly alleviates the congestion on the link, but also reduces vehicle exhaust emissions within the network by up to 41.56%.

Mixed Transportation Network Design under a Sustainable Development Perspective

Science.gov (United States)

Qin, Jin; Ni, Ling-lin; Shi, Feng

2013-01-01

A mixed transportation network design problem considering sustainable development was studied in this paper. Based on the discretization of continuous link-grade decision variables, a bilevel programming model was proposed to describe the problem, in which sustainability factors, including vehicle exhaust emissions, land-use scale, link load, and financial budget, are considered. The objective of the model is to minimize the total amount of resources exploited under the premise of meeting all the construction goals. A heuristic algorithm, which combined the simulated annealing and path-based gradient projection algorithm, was developed to solve the model. The numerical example shows that the transportation network optimized with the method above not only significantly alleviates the congestion on the link, but also reduces vehicle exhaust emissions within the network by up to 41.56%. PMID:23476142

Sistema de gestión estadística: Hechos vitales e identificados

OpenAIRE

Díaz Echenique, Melchor Angel; Díaz Echenique, Melchor Angel; Díaz Echenique, Melchor Angel

2011-01-01

La presente Tesis para optar el grado de Magíster en Ciencias con mención en Ingeniería de Sistemas se titula: "SISTEMA DE GESTION ESTADISTICA: HECHOS VITALES E IDENTIFICACION". El Problema, en el que se centra la presente tesis, exige responder a la interrogante: ¿Se presentan o producen empirismos normativos, incumplimientos, deficiencias y restricciones en el Sistema de Gestión Estadística: ¿Hechos Vitales e Identificación? El Problema tiene 4 partes con las siguientes prioridad...

Nuclear transport - The regulatory dimension

International Nuclear Information System (INIS)

Green, L.

2002-01-01

The benefits that the peaceful applications of nuclear energy have brought to society are due in no small part to industry's capacity to transport radioactive materials safely, efficiently and reliably. The nuclear transport industry has a vital role in realising a fundamental objective of the International Atomic Energy Agency (IAEA) as stated in its statute to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world. The context in which transports currently take place is complex, and rapidly changing. In many respects transport is being viewed as an integral market issue and not a subsidiary concern. The availability of carriers drives routing decisions and changes in material flows necessitate new approaches to packaging and transport scenarios. Pressures on the transport sector are not without serious consequences; they can cause delays and in some cases cancellation of planned movements. Complex routings and the necessary use of chartered carriers can push up costs and work against cost efficiency. Since the events of 11 September 2001 the security of nuclear transports has contributed an added dimension to how transports take place. Transports of radioactive material have an outstanding safety record, indeed the transport of such materials could be regarded as a model for the transport of other classes of dangerous goods. This safety record is achieved by two inter-related factors. It is due primarily to well founded regulations developed by such key intergovernmental organisations as the IAEA, with the essential contributions of the member states who participate in the implementation of regulations and the review process. It is due also to the professionalism of those in the industry. There is a necessary synergy between the two - between the regulators whose task it is to make and to enforce the rules for safe, efficient and reliable transport and those whose job it is to transport within the rules. It

CDC Vital Signs–HIV Testing

Centers for Disease Control (CDC) Podcasts

2017-11-28

This podcast is based on the December 2017 CDC Vital Signs report. In the U.S., about 15 percent of people who have HIV don't know they have it. Learn about the importance of testing, early diagnosis, and treatment.  Created: 11/28/2017 by Centers for Disease Control and Prevention (CDC).   Date Released: 11/28/2017.

Vital Signs – Prescription Painkiller Overdoses

Centers for Disease Control (CDC) Podcasts

2013-07-02

This podcast is based on the July 2013 CDC Vital Signs report. Prescription painkiller overdoses are an under-recognized and growing problem among women. This program includes things that women and health care providers can do to reduce the risk of overdose.  Created: 7/2/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/2/2013.

Vital Signs – Defeating Breast Cancer

Centers for Disease Control (CDC) Podcasts

This podcast is based on the November 2012 CDC Vital Signs report. Breast cancer is the second leading cause of cancer deaths among women in the United States. Better screening and treatment have contributed to a decline in breast cancer deaths, however, not all women have benefited equally from these improvements. Learn how we can all help reduce deaths from breast cancer.

The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2.

Science.gov (United States)

Shukla, Suneet; Wu, Chung-Pu; Nandigama, Krishnamachary; Ambudkar, Suresh V

2007-12-01

Vitamin K3 (menadione; 2-methyl-1,4-naphthoquinone) is a structural precursor of vitamins K1 and K2, which are essential for blood clotting. The naturally occurring structural analogue of this vitamin, plumbagin (5-hydroxy-menadione), is known to modulate cellular proliferation, apoptosis, carcinogenesis, and radioresistance. We here report that both vitamin K3 and plumbagin are substrates of the multidrug resistance-linked ATP binding cassette drug transporter, ABCG2. Vitamin K3 and plumbagin specifically inhibited the ABCG2-mediated efflux of mitoxantrone but did not have any effect on the ABCB1-mediated efflux of rhodamine 123. This inhibition of ABCG2 function was due to their interaction at the substrate-binding site(s). Vitamin K3 and plumbagin inhibited the binding of [(125)I]iodoarylazidoprazosin, a substrate of ABCG2, to this transporter in a concentration-dependent manner with IC(50) values of 7.3 and 22.6 micromol/L, respectively, but had no effect on the binding of the photoaffinity analogue to ABCB1. Both compounds stimulated ABCG2-mediated ATP hydrolysis and also inhibited the mitoxantrone-stimulated ATPase activity of the ABCG2 transporter, but did not have any significant effect on the ATPase activity of ABCB1. In a cytotoxicity assay, ABCG2-expressing HEK cells were 2.8- and 2.3-fold resistant to plumbagin and vitamin K3, respectively, compared with the control cells, suggesting that they are substrates of this transporter. Collectively, these data show for the first time that vitamin K3 is a substrate of the ABCG2 transporter. Thus, ABCG2 may have a role in the regulation of vitamin K3 levels in the body. In addition, vitamin K3 and its structural derivative, plumbagin, could potentially be used to modulate ABCG2 function.

The Relationship between Test Anxiety and Academic Performance of Students in Vital Statistics Course

Directory of Open Access Journals (Sweden)

Shirin Iranfar

2013-12-01

Full Text Available Introduction: Test anxiety is a common phenomenon among students and is one of the problems of educational system. The present study was conducted to investigate the test anxiety in vital statistics course and its association with academic performance of students at Kermanshah University of Medical Sciences. This study was descriptive-analytical and the study sample included the students studying in nursing and midwifery, paramedicine and health faculties that had taken vital statistics course and were selected through census method. Sarason questionnaire was used to analyze the test anxiety. Data were analyzed by descriptive and inferential statistics. The findings indicated no significant correlation between test anxiety and score of vital statistics course.

3 CFR 8377 - Proclamation 8377 of May 11, 2009. National Defense Transportation Day and National...

Science.gov (United States)

2010-01-01

... modes of travel save businesses and consumers money, and can reduce impacts on our environment. To..., transportation is vital to keeping Americans safe. Global climate change and our reliance on foreign oil have... thousands of jobs. To make the most of every taxpayer dollar, my Administration is working side-by-side with...

Scintigraphic test of the vitality and functional fitness of organs conserved for transplantation

International Nuclear Information System (INIS)

Bozduganov, A.; Marinov, V.

1976-01-01

Having reviewed critically present-day methods of testing the vitality of isolated perfused organs, the authors propose their own. It is founded in the principles of colour scintigraphy after introduction of short-lived nuclides. The method was applied in testing 57 isolated preserved organs (5 kidneys, 12 livers, 5 hearts and 4 spleens from dogs; 2 kidneys and 27 livers from rabbits; 1 kidney and 1 liver from young pigs). Moreover, compararive scintigraphic and biochemical investigations were conducted on 2 dogs and 4 young pigs (A. Bozduganov, E. Simeonov, N. Bogdanova). The techniques of isolation and perfusion of the organ have been given a detailed description. Sup(113m)In was used as tracer. Areas of radioactivity deposits were visualized more or less intensely, depending on the degree of vitality and functional fitness still present actually; else, blanks were seen. Orthotransplantation and heterotransplantation with subsequent scintigraphic examination in vivo served, in scattered instances, the purpose of confirming or of rejecting ambiguous vitality findings in preserved organs. Advantages of the method are a general and specified evaluation of the organ in all of its areas; anatomical integrity of the object under test; applicability to various organs; possibility of conducting dynamic tests; accurate reproduction of vitality and functional findings, etc

Bleaching in vital deciduous teeth – a clinical case

Directory of Open Access Journals (Sweden)

José Carlos Pettorossi Imparato

2008-01-01

Full Text Available There has been growing concern and search for esthetic beauty and harmony over the last few years. This concern does not form part ofadults’ lives only, but also of children’s. Among the substances used for bleaching dental structures, the most outstanding are those whoseactive principle is hydrogen peroxide-based . The present study reports a clinical case of a 4-year-old girl that suffered trauma of tooth 61 with consequent color alteration, but with no alteration in pulp vitality. The main complaint by the patient and her guardians concerned esthetics, therefore external dental bleaching was performed, using Opalescence Xtra® (Ultradent, in two sessions with an interval of one month between them. External in office bleaching was the treatment of choice, due to the tooth vitality, patient’s age and presence of only one darkened tooth. After the bleaching treatments an improvement in the darkening was observed, and both the child and her guardians were satisfied with the esthetic result.

CDC Signos Vitales: Enfermedad del legionario (CDC Vital Signs–Legionnaires’ Disease)

Centers for Disease Control (CDC) Podcasts

2016-06-07

Este podcast se basa en la edición de junio del 2016 del informe Signos Vitales de los CDC. Las personas pueden contraer la enfermedad del legionario, un tipo grave de infección pulmonar, al inhalar pequeñas gotitas de agua contaminada con bacterias Legionella. Obtenga más información sobre lo que se puede hacer para ayudar a prevenir brotes de enfermedad del legionario y mantener seguras a las personas.  Created: 6/7/2016 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 6/7/2016.

Integrating community-based verbal autopsy into civil registration and vital statistics (CRVS): system-level considerations

Science.gov (United States)

de Savigny, Don; Riley, Ian; Chandramohan, Daniel; Odhiambo, Frank; Nichols, Erin; Notzon, Sam; AbouZahr, Carla; Mitra, Raj; Cobos Muñoz, Daniel; Firth, Sonja; Maire, Nicolas; Sankoh, Osman; Bronson, Gay; Setel, Philip; Byass, Peter; Jakob, Robert; Boerma, Ties; Lopez, Alan D.

2017-01-01

ABSTRACT Background: Reliable and representative cause of death (COD) statistics are essential to inform public health policy, respond to emerging health needs, and document progress towards Sustainable Development Goals. However, less than one-third of deaths worldwide are assigned a cause. Civil registration and vital statistics (CRVS) systems in low- and lower-middle-income countries are failing to provide timely, complete and accurate vital statistics, and it will still be some time before they can provide physician-certified COD for every death. Proposals: Verbal autopsy (VA) is a method to ascertain the probable COD and, although imperfect, it is the best alternative in the absence of medical certification. There is extensive experience with VA in research settings but only a few examples of its use on a large scale. Data collection using electronic questionnaires on mobile devices and computer algorithms to analyse responses and estimate probable COD have increased the potential for VA to be routinely applied in CRVS systems. However, a number of CRVS and health system integration issues should be considered in planning, piloting and implementing a system-wide intervention such as VA. These include addressing the multiplicity of stakeholders and sub-systems involved, integration with existing CRVS work processes and information flows, linking VA results to civil registration records, information technology requirements and data quality assurance. Conclusions: Integrating VA within CRVS systems is not simply a technical undertaking. It will have profound system-wide effects that should be carefully considered when planning for an effective implementation. This paper identifies and discusses the major system-level issues and emerging practices, provides a planning checklist of system-level considerations and proposes an overview for how VA can be integrated into routine CRVS systems. PMID:28137194

L’ipotesi del ciclo vitale, la politica fiscale e la previdenza sociale

Directory of Open Access Journals (Sweden)

Tullio Jappelli

2005-06-01

Full Text Available Il lavoro riassume le principali implicazioni dell’ipotesi del ciclo vitale per quanto riguarda il risparmio individuale e aggregato, la politica fiscale e la previdenza sociale, soffermandosi sui contributi più importanti di Modigliani su questi temi. Anche se non è facile conciliare alcuni risultati empirici recenti con l’ipotesi del ciclo vitale, soprattutto gli aspetti di inerzia, miopia e comportamento irrazionale documentati nella letteratura comportamentale, gli studi di Modigliani rappresentano ancora oggi la base di riferimento principale per studiare le decisioni dirisparmio individuali e per operare scelte di politica economica.

Theoretical study on mechanical and electron-transport properties of conjugated molecular junctions with carboxylic or methyl sulfide links

Energy Technology Data Exchange (ETDEWEB)

Bao, De-Liang; Liu, Ran [College of Physics and Electronics, Shandong Normal University, Jinan 250014 (China); Leng, Jian-Cai [College of Physics and Electronics, Shandong Normal University, Jinan 250014 (China); School of Science, Qilu University of Technology, Jinan 250353 (China); Zuo, Xi; Jiao, Yang [College of Physics and Electronics, Shandong Normal University, Jinan 250014 (China); Li, Zong-Liang, E-mail: lizongliang@sdnu.edu.cn [College of Physics and Electronics, Shandong Normal University, Jinan 250014 (China); Wang, Chuan-Kui [College of Physics and Electronics, Shandong Normal University, Jinan 250014 (China)

2014-03-01

The mechanical and electronic transport properties of 4-(methylthio)benzoic acid (M1), 1,4-bis(methylthio) benzene (M2) and methyl 4-(methylthio)benzoate (M3) molecular junctions are studied employing density functional theory and elastic scattering Green's function method. The numerical results show that the rupture force of M1 and M2 junctions are both about 0.6±0.1 nN as experiment probed, which is much smaller than the force to break COO{sup −}–Au bond. The COO{sup −} group strongly influenced on M1 molecular junction and further strengthened SMe–Au bond at the other end of the junction. The M3 junction is less stable because the CH{sub 3} group linked to COO group destroyed the mechanical stability of COO–Au connection. The conductance of M2 junction is about an order larger than that of M1 junction as the experiment probed. The less stable feature of M3 junction leads the absence of conductive peak.

Radiotracer investigations for sediment transport in ports of India

International Nuclear Information System (INIS)

Pant, H.J.; Sharma, V.K.; Goswami, Sunil; Singh, Gursharan

2013-01-01

The knowledge of mixing and transport of sediments in coastal region is of vital importance for evaluating suitability of dumping site for dredged sediments produced during maintenance of shipping channels, expansion of existing projects and construction of new projects. Gamma-emitting radiotracers are commonly used for investigation of movement of sediments on seabed using Scandium-46 (scandium glass powder) as radiotracer. The radiotracer is injected on seabed at a desired location and its movement followed over a period of time using waterproof NaI(Tl) scintillation detectors. The recorded data is analyzed to obtain transport parameters and utilized for assessing the suitability of the dumping sites and optimization of the dredging operations. About 70 large-scale investigations have been carried out in different ports in India leading to significant economical benefits to the Ports. Present paper discusses various aspects of the radiotracer technique for sediment transport, methodology of data analysis and a specific case study. (author)

Technical evaluation report on the 120 Vac vital instrument buses and inverter Technical Specifications Issue B71

International Nuclear Information System (INIS)

St Leger-Barter, G.; White, R.L.

1982-01-01

The operation of a Pressurized Water Reactor (PWR) with one of its 120 Vac vital buses energized in an off-normal mode was analyzed. A Probabilistic Risk Assessment was made to determine the increment of risk by energizing a vital bus from an off-site source directly vs energizing it from its normal, uninterruptible source (i.e., a battery/inverter arrangement). The calculations were made based on uninterruptible source energized vital buses as the normal mode. The analysis indicated that a reduction in the incremental risk increase (caused by plant operation with a vital bus being energized in an off-normal mode) can be accomplished by limiting the time permitted in that condition. Currently, the time that a vital bus can be energized in the off-normal mode is not universally time-limited by plant Technical Specifications. Several alternatives for the reduction in incremental risk were examined and their value/impacts were derived. These data indicate that a recommendation be made for a Technical Specification time limitation of 72 hours per year for off-normal energizing a vital bus during operation of a PWR

Speech control interface for Eurocontrol’s LINK2000+ system

Directory of Open Access Journals (Sweden)

Dan-Cristian ION

2012-06-01

Full Text Available This paper continues recent research of the authors, considering the use of speech recognition in air traffic control. It proposes the use of a voice control interface for Eurocontrol’s LINK2000+ system, offering an alternative means to improve air transport safety and efficiency.

LongoVital in the prevention of recurrent aphthous ulceration

DEFF Research Database (Denmark)

Pedersen, A; Hougen, H P; Klausen, B

1990-01-01

LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during 6 months' daily intake of LV as compared with placebo in a double-blind, randomized...

Mineral extraction and transport device

Energy Technology Data Exchange (ETDEWEB)

Plaga, K.

1991-08-21

A device for the extraction and transport of stratified mineral deposits notably coal, having a transport run with lengths of transport troughing, an extraction run with lengths of extraction troughing, and a power-driven traction chain guided round return devices and carrying extraction bodies together with optional transport units. The transport and extraction troughing have guide members on which the extraction bodies and the transport units are guided with the aid of guide formations. Each extraction body consists of a headpiece having two laterally protruding guide formations, and an endpiece having two laterally protruding guide formations and a centrepiece. The headpiece and the endpiece are swivellably linked to the centrepiece through an axis running substantially at right angles to the traction axis of the traction chain and substantially at right angles to the floor of the lengths of transport troughing in the transport run. The centrepiece has an additional articulation about an axis substantially orthogonal to the swivel axis of the headpiece and the endpiece. Guide members are additionally provided in the vicinity of the return devices whereby the guide formations on each headpiece and endpiece receive continued guidance.

Subjective Vitality as Mediator and Moderator of the Relationship between Life Satisfaction and Subjective Happiness

Science.gov (United States)

Uysal, Recep; Satici, Seydi Ahmet; Satici, Begüm; Akin, Ahmet

2014-01-01

In this study, the mediator and moderator effects of subjective vitality on the relationship between life satisfaction and subjective happiness were investigated. The participants were 378 university students who completed a questionnaire package that included the Subjective Vitality Scale, the Satisfaction with Life Scale, and the Subjective…

Vital Signs-Physical Activity and Adults with Disabilities

Centers for Disease Control (CDC) Podcasts

2014-05-06

This podcast is based on the May 2014 CDC Vital Signs report. Adults with disabilities who get no aerobic physical activity are 50 percent more likely to have heart disease, stroke, diabetes, or cancer. Learn what you can do to help.  Created: 5/6/2014 by National Center on Birth Defects and Developmental Disabilities (NCBDDD).   Date Released: 5/6/2014.

The capacity of radar, crowdsourced personal weather stations and commercial microwave links to monitor small scale urban rainfall

Science.gov (United States)

Uijlenhoet, R.; de Vos, L. W.; Leijnse, H.; Overeem, A.; Raupach, T. H.; Berne, A.

2017-12-01

For the purpose of urban rainfall monitoring high resolution rainfall measurements are desirable. Typically C-band radar can provide rainfall intensities at km grid cells every 5 minutes. Opportunistic sensing with commercial microwave links yields rainfall intensities over link paths within cities. Additionally, recent developments have made it possible to obtain large amounts of urban in situ measurements from weather amateurs in near real-time. With a known high resolution simulated rainfall event the accuracy of these three techniques is evaluated, taking into account their respective existing layouts and sampling methods. Under ideal measurement conditions, the weather station networks proves to be most promising. For accurate estimation with radar, an appropriate choice for Z-R relationship is vital. Though both the microwave links and the weather station networks are quite dense, both techniques will underestimate rainfall if not at least one link path / station captures the high intensity rainfall peak. The accuracy of each technique improves when considering rainfall at larger scales, especially by increasing time intervals, with the steepest improvements found in microwave links.

A proposed study on the transplacental transport of parabens in the human placental perfusion model

DEFF Research Database (Denmark)

Mathiesen, Line; Zuri, Giuseppina; Andersen, Maria H

2013-01-01

, but the available data are sparse. The aim is to develop a method for estimating fetal exposure, via the placenta, to the most commonly-used parabens, by using a human placental perfusion model. The use of human tissue is vital for determining human fetal exposure, because animal studies are of little relevance...... to determine the transport kinetics of these parabens across the human placenta, and to investigate placental metabolism, including differences in transport due to molecular characteristics. This will facilitate assessment of the risks associated with the use of paraben-containing products during pregnancy....

Looking on the bright side of serotonin transporter gene variation.

NARCIS (Netherlands)

Homberg, J.R.; Lesch, K.P.

2011-01-01

Converging evidence indicates an association of the short (s), low-expressing variant of the repeat length polymorphism, serotonin transporter-linked polymorphic region (5-HTTLPR), in the human serotonin transporter gene (5-HTT, SERT, SLC6A4) with anxiety-related traits and increased risk for

Endocrine regulation of ion transport in the avian lower intestine

DEFF Research Database (Denmark)

Laverty, Gary; Elbrønd, Vibeke Sødring; Árnason, Sighvatur S.

2006-01-01

The lower intestine (colon and coprodeum) of the domestic fowl maintains a very active, transporting epithelium, with a microvillus brush border, columnar epithelial cells, and a variety of transport systems. The colon of normal or high salt-acclimated hens expresses sodium-linked glucose and amino...

Algorithmic tools for interpreting vital signs.

Science.gov (United States)

Rathbun, Melina C; Ruth-Sahd, Lisa A

2009-07-01

Today's complex world of nursing practice challenges nurse educators to develop teaching methods that promote critical thinking skills and foster quick problem solving in the novice nurse. Traditional pedagogies previously used in the classroom and clinical setting are no longer adequate to prepare nursing students for entry into practice. In addition, educators have expressed frustration when encouraging students to apply newly learned theoretical content to direct the care of assigned patients in the clinical setting. This article presents algorithms as an innovative teaching strategy to guide novice student nurses in the interpretation and decision making related to vital sign assessment in an acute care setting.

Vital forces and organization: philosophy of nature and biology in Karl Friedrich Kielmeyer.

Science.gov (United States)

Gambarotto, Andrea

2014-12-01

The historical literature on German life science at the end of the 18th century has tried to rehabilitate eighteenth century vitalism by stressing its difference from Naturphilosophie. Focusing on the work of Karl Friedrich Kielmeyer this paper argues that these positions are based on a historiographical bias and that the clear-cut boundary between German vitalism and Naturphilosophie is historically unattested. On the contrary, they both belong to the process of conceptual genealogy that contributed to the project of a general biology. The latter emerged as the science concerned with the laws that regulate the organization of living nature as a whole. The focus on organization was, at least partially, the result of the debate surrounding the notion of "vital force", which originated in the mid-eighteenth century and caused a shift from a regulative to a constitutive understanding of teleology. Copyright © 2014 Elsevier Ltd. All rights reserved.

The GPI transportation accounts : sustainable transportation in Halifax Regional Municipality

Energy Technology Data Exchange (ETDEWEB)

Savelson, A.; Colman, R.; Martin, W. [GPI Atlantic, Halifax, NS (Canada)

2008-03-15

The Halifax Regional Municipality (HRM) approved its first municipal planning strategy (MPS), in June 2006 that set the general framework for planning decisions over the next 20 years. The major objectives of this initiative are to manage a moderate level of population growth, minimize the environmental impact of that growth, and use it as a catalyst to make HRM more sustainable in all of its activities. Due to the dispersed nature of HRM and the diverse mix of its urban, suburban, and rural areas, the links between communities become a key focal point for sustainability measures. Transportation issues are central to many of HRM's current planning decisions and are a key component of the MPS. This report summarized the portion of the MPS that related to the development of functional transportation plans for HRM. The report also presented findings for eight key indicator categories that could be utilized to assess the sustainability of HRM's transportation system. These indicator categories include transport activity; energy consumption; greenhouse gas emissions; transportation emissions of air pollutants; land use and transportation; access to basic services; access to public transportation; neighbourhood quality of life; and household spending on transportation. The report also provided a quantitative assessment of the economic costs of passenger road transportation in HRM. The costing section provided estimates for 15 cost categories, many of which go unexamined in standard transportation accounting mechanisms. Last, a set of data and policy recommendations outlining ways to improve transportation monitoring in HRM as well as to advance the sustainability of HRM's transportation system as a whole were presented. Recommendations included: establishing settlement patterns and pedestrian or cycling-oriented infrastructure where more people could walk or cycle to work and amenities; increasing ridership by making transit accessible to a wider

The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism.

Science.gov (United States)

Mulligan, Christopher; Fenollar-Ferrer, Cristina; Fitzgerald, Gabriel A; Vergara-Jaque, Ariela; Kaufmann, Desirée; Li, Yan; Forrest, Lucy R; Mindell, Joseph A

2016-03-01

Secondary transporters use alternating-access mechanisms to couple uphill substrate movement to downhill ion flux. Most known transporters use a 'rocking bundle' motion, wherein the protein moves around an immobile substrate-binding site. However, the glutamate-transporter homolog GltPh translocates its substrate-binding site vertically across the membrane, through an 'elevator' mechanism. Here, we used the 'repeat swap' approach to computationally predict the outward-facing state of the Na(+)/succinate transporter VcINDY, from Vibrio cholerae. Our model predicts a substantial elevator-like movement of VcINDY's substrate-binding site, with a vertical translation of ~15 Å and a rotation of ~43°. Our observation that multiple disulfide cross-links completely inhibit transport provides experimental confirmation of the model and demonstrates that such movement is essential. In contrast, cross-links across the VcINDY dimer interface preserve transport, thus revealing an absence of large-scale coupling between protomers.

The Role of Tree Mortality in Vitality Assessment of Sessile Oak Forests

Directory of Open Access Journals (Sweden)

Imre Berki

2016-12-01

Full Text Available Background and Purpose: The drought-induced vitality loss of sessile oak (Quercus petraea (Matt. Liebl. has been continuously observed in Hungary for more than three decades. The decrease in stand density as a consequence of drought-induced mortality has not been taken into consideration in most of the monitoring methods. Materials and Methods: Forest stands without any forest intervention during the last 30 years were selected. Quadrats were designated for the analysis in 18 sessile oak stands along a climatic transect in which foliage transparency and stand density were measured. Drought stress was defined by the water balance approach. By combining the foliage transparency and the relative stand density, a new cumulative assessment method of stand level vitality was introduced to get a more realistic picture about the effects of long-term drought (lasting for several decades on the sessile oak forests in South-East Europe. Results: The calculated health status (100% - vital; 0% - dead of the sessile oak stands was between 70-90% in the moist South-West Hungary and below 50% close to its xeric limit. The individual tree-based vitality assessment method gave considerably higher values on 17 out of 18 sites. Conclusions: Forest monitoring should also consider stand level-based tree mortality in oak forests while assessing health condition especially close to its xeric limit. The proposed new method provides a more realistic picture about the effects of climate change on sessile oak stands particularly for forest managers interested in changing in the wood stock of forests.

VIPEX (Vital-area Identification Package EXpert) Software Verification and Validation

International Nuclear Information System (INIS)

Jung, Woo Sik; Suh, Jae Seung

2010-06-01

The purposes of this report are (1) to perform a Verification and Validation (V and V) test for the VIPEX(Vital-area Identification Package EXpert) software and (2) to improve a software quality through the V and V test. The VIPEX was developed in Korea Atomic Energy Research Institute (KAERI) for the Vital Area Identification (VAI) of nuclear power plants. The version of the VIPEX which was distributed is 3.2.0.0. The VIPEX was revised based on the first V and V test and the second V and V test was performed. We have performed the following tasks for the V and V test on Windows XP and VISTA operating systems: Ο Testing basic functions including fault tree editing Ο Testing all kind of functions Ο Research for update from Visual BASIC 6.0 to Visual BASIC 2008

Mid-Career Faculty Development in Academic Medicine: How Does It Impact Faculty and Institutional Vitality?

Science.gov (United States)

Campion, MaryAnn W.; Bhasin, Robina M.; Beaudette, Donald J.; Shann, Mary H.; Benjamin, Emelia J.

2016-01-01

Purpose: Faculty vitality is integral to the advancement of higher education. Strengthening vitality is particularly important for midcareer faculty, who represent the largest and most dissatisfied segment. The demands of academic medicine appear to be another factor that may put faculty at risk of attrition. To address these issues, we initiated…

Anaesthetic indices and vital parameters of PPR-infected West ...

African Journals Online (AJOL)

The aim of this study, was to assess and compare the anaesthetic indices and vital parameters of West African Dwarf (WAD) goats naturally infected with PPR before and after epidural anaesthesia with plain lignocaine and also to compare the measured anaesthetic indices with those of healthy goats. Ten goats were used ...

Vital Signs – Preventing Repeat Teen Births

Centers for Disease Control (CDC) Podcasts

2013-04-02

This podcast is based on the April 2013 CDC Vital Signs report, which discusses repeat teen births and ways teens, parents and guardians, health care providers, and communities can help prevent them.  Created: 4/2/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 4/2/2013.

Neutron and gamma-ray transport experiments in liquid air

International Nuclear Information System (INIS)

Farley, W.E.

1976-01-01

Accurate estimates of neutron and gamma radiations from a nuclear explosion and their subsequent transport through the atmosphere are vital to nuclear-weapon employment studies: i.e., for determining safety radii for aircraft crews, casualty and collateral-damage risk radii for tactical weapons, and the kill range from a high-yield defensive burst for a maneuvering reentry vehicle. Radiation transport codes, such as the Laboratory's TARTNP, are used to calculate neutron and gamma fluences. Experiments have been performed to check and update these codes. Recently, a 1.3-m-radius liquid-air (21 percent oxygen) sphere, with a pulsed source of 14-MeV neutrons at its center, was used to measure the fluence and spectra of emerging neutrons and secondary gamma rays. Comparison of measured radiation dose with TARTNP showed agreement within 10 percent

Multimodal public transport : an analysis of travel time elements and the interconnectivity ratio

NARCIS (Netherlands)

Krygsman, S.; Dijst, M.J.; Arentze, T.A.

2004-01-01

Access and egress are the weakest links in a public transport chain and determine the availability and convenience of public transport. Initiatives aimed at improving access and egress hold potential to significantly reduce public transport trip time and are inexpensive options compared to the

Psicología del ciclo vital: hacia una visión comprehensiva de la vida humana

OpenAIRE

Elisa Dulcey Ruiz; Cecilia Uribe Valdivieso

2002-01-01

Se propone que la psicología del ciclo vital es más amplia que la psicología del desarrollo. Coherente con una visión integral del curso del ciclo vital esta psicología enfatiza la irrelevancia de la edad, los cambios permanentes, la multidimensionalidad, y la plasticidad, también como la importancia del contexto y la historia. Se refiere al proceso de envejecimiento, a la adultez, la vejez y la muerte en el marco del ciclo vital; enfatiza posibilidades relacionadas con el envejecimiento exit...

Psicología del ciclo vital: hacia una visión comprehensiva de la vida humana

OpenAIRE

Elisa Dulcey Ruiz; Cecilia Uribe Valdivieso

2002-01-01

Se propone que la psicología del ciclo vital es más amplia que la psicología del desarrollo. Coherente con una visión integral del curso del ciclo vital esta psicología enfatiza la irrelevancia de la edad, los cambios permanentes, la multidimensionalidad, y la plasticidad, también como la importancia del contexto y la historia. Se refiere al proceso de envejecimiento, a la adultez, la vejez y la muerte en el marco del ciclo vital; enfatiza posibilidades relacionadas con el enve...

Noise considerations for vital signs CW radar sensors

DEFF Research Database (Denmark)

Jensen, Brian Sveistrup; Jensen, Thomas; Zhurbenko, Vitaliy

2011-01-01

and the underlying signal theory for such sensors. Then to point out and especially clarify one of the most important effects aiding the design of vital signs radars (VSR), a more detailed discussion concerning phase noise cancellation (or filtering) by range correlation is given. This discussion leads to some...... general conclusions about which system components are the most critical concerning noise contribution and thus detection accuracy and dynamic range....

CDC Vital Signs: Heart Age - Is Your Heart Older Than You?

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

CDC Vital Signs: Making Health Care Safer -- Think Sepsis. Time Matters.

Science.gov (United States)

... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

Magneto-electrical transport through MBE-grown III-V semiconductor nanostructures. From zero- to one-dimensional type of transport

International Nuclear Information System (INIS)

Storace, Eleonora

2009-01-01

From the development of the first transistor in 1947, great interest has been directed towards the technological development of semiconducting devices and the investigation of their physical properties. A very vital field within this topic focuses on the electrical transport through low-dimensional structures, where the quantum confinement of charge carriers leads to the observation of a wide variety of phenomena that, in their turn, can give an interesting insight on the fundamental properties of the structures under examination. In the present thesis, we will start analyzing zero-dimensional systems, focusing on how electrons localized onto an island can take part in the transport through the whole system; by precisely tuning the tunnel coupling strength between this island and its surroundings, we will then show how it is possible to move from a zero- to a one-dimensional system. Afterwards, the inverse path will be studied: a one-dimensional system is electrically characterized, proving itself to split up due to disorder into several zero-dimensional structures. (orig.)

Magneto-electrical transport through MBE-grown III-V semiconductor nanostructures. From zero- to one-dimensional type of transport

Energy Technology Data Exchange (ETDEWEB)

Storace, Eleonora

2009-07-08

From the development of the first transistor in 1947, great interest has been directed towards the technological development of semiconducting devices and the investigation of their physical properties. A very vital field within this topic focuses on the electrical transport through low-dimensional structures, where the quantum confinement of charge carriers leads to the observation of a wide variety of phenomena that, in their turn, can give an interesting insight on the fundamental properties of the structures under examination. In the present thesis, we will start analyzing zero-dimensional systems, focusing on how electrons localized onto an island can take part in the transport through the whole system; by precisely tuning the tunnel coupling strength between this island and its surroundings, we will then show how it is possible to move from a zero- to a one-dimensional system. Afterwards, the inverse path will be studied: a one-dimensional system is electrically characterized, proving itself to split up due to disorder into several zero-dimensional structures. (orig.)

Recent advances on uric acid transporters

Science.gov (United States)

Xu, Liuqing; Shi, Yingfeng; Zhuang, Shougang; Liu, Na

2017-01-01

Uric acid is the product of purine metabolism and its increased levels result in hyperuricemia. A number of epidemiological reports link hyperuricemia with multiple disorders, such as kidney diseases, cardiovascular diseases and diabetes. Recent studies also showed that expression and functional changes of urate transporters are associated with hyperuricemia. Uric acid transporters are divided into two categories: urate reabsorption transporters, including urate anion transporter 1 (URAT1), organic anion transporter 4 (OAT4) and glucose transporter 9 (GLUT9), and urate excretion transporetrs, including OAT1, OAT3, urate transporter (UAT), multidrug resistance protein 4 (MRP4/ABCC4), ABCG-2 and sodium-dependent phosphate transport protein. In the kidney, uric acid transporters decrease the reabsorption of urate and increase its secretion. These transporters’ dysfunction would lead to hyperuricemia. As the function of urate transporters is important to control the level of serum uric acid, studies on the functional role of uric acid transporter may provide a new strategy to treat hyperuricemia associated diseases, such as gout, chronic kidney disease, hyperlipidemia, hypertension, coronary heart disease, diabetes and other disorders. This review article summarizes the physiology of urate reabsorption and excretion transporters and highlights the recent advances on their roles in hyperuricemia and various diseases. PMID:29246027

Vital area identification software VIP for the physical protection of nuclear power plants

International Nuclear Information System (INIS)

Jung, Woo Sik; Park, Chang Kue; Yang, Joon Eon

2004-01-01

There are two major factors to be considered for the physical protection of nuclear power plants. They are a design basis threat (DBT) and the vital area identification (VAI). The DBT has been considered as 'the maximum credible threat.' The vital area is defined as 'an area inside a protected area containing equipment, systems or devices, or nuclear materials, the sabotage of which could directly or indirectly lead to unacceptable radiological consequences.' For the VAI of nuclear power plants, a software VIP (Vital area Identification Package based on PSA method) is being developed. The VIP is based on the current probabilistic safety assessment (PSA) techniques. The PSA method, including internal as well as external events, is known as the most complete and consistent method for identifying various accident sequences that might result in a core melt and radioactive material release to the environment. Thus, the VIP employs a fault tree analysis method in the PSA and utilizes the PSA results

Vital Signs – Alcohol Screening and Counseling?

Centers for Disease Control (CDC) Podcasts

2014-01-07

This podcast is based on the January 2014 CDC Vital Signs report. Millions of Americans drink too much, a dangerous behavior that can lead to serious health problems. Alcohol screening and counseling can help.  Created: 1/7/2014 by Centers for Disease Control and Prevention (CDC).   Date Released: 1/7/2014.

Vital Signs – Making Health Care Safer

Centers for Disease Control (CDC) Podcasts

2013-03-05

This podcast is based on the March 2013 CDC Vital Signs report, which discusses lethal infections from carbapenem-resistant Enterobacteriaceae, or CRE, germs and ways health care providers can help stop CRE infections.  Created: 3/5/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 3/5/2013.

Calibration of Linked Hydrodynamic and Water Quality Model for Santa Margarita Lagoon

Science.gov (United States)

2016-07-01

was used to drive the transport and water quality kinetics for the simulation of 2007–2009. The sand berm, which controlled the opening/closure of...TECHNICAL REPORT 3015 July 2016 Calibration of Linked Hydrodynamic and Water Quality Model for Santa Margarita Lagoon Final Report Pei...Linked Hydrodynamic and Water Quality Model for Santa Margarita Lagoon Final Report Pei-Fang Wang Chuck Katz Ripan Barua SSC Pacific James

Assumptions and Policy Decisions for Vital Area Identification Analysis

Energy Technology Data Exchange (ETDEWEB)

Kim, Myungsu; Bae, Yeon-Kyoung; Lee, Youngseung [KHNP CRI, Daejeon (Korea, Republic of)

2016-10-15

U.S. Nuclear Regulatory Commission and IAEA guidance indicate that certain assumptions and policy questions should be addressed to a Vital Area Identification (VAI) process. Korea Hydro and Nuclear Power conducted a VAI based on current Design Basis Threat and engineering judgement to identify APR1400 vital areas. Some of the assumptions were inherited from Probabilistic Safety Assessment (PSA) as a sabotage logic model was based on PSA logic tree and equipment location data. This paper illustrates some important assumptions and policy decisions for APR1400 VAI analysis. Assumptions and policy decisions could be overlooked at the beginning stage of VAI, however they should be carefully reviewed and discussed among engineers, plant operators, and regulators. Through APR1400 VAI process, some of the policy concerns and assumptions for analysis were applied based on document research and expert panel discussions. It was also found that there are more assumptions to define for further studies for other types of nuclear power plants. One of the assumptions is mission time, which was inherited from PSA.

FM-CW radar sensors for vital signs and motor activity monitoring

Directory of Open Access Journals (Sweden)

Octavian Adrian Postolache

2011-12-01

Full Text Available The article summarizes on-going research on vital signs and motor activity monitoring based on radar sensors embedded in wheelchairs, walkers and crutches for in home rehabilitation. Embedded sensors, conditioning circuits, real-time platforms that perform data acquisition, auto-identification, primary data processing and data communication contribute to convert daily used objects in home rehabilitation into smart objects that can be accessed by caregivers during the training sessions through human–machine interfaces expressed by the new generation of smart phones or tablet computers running Android OS or iOS operating systems. The system enables the management of patients in home rehabilitation by providing more accurate and up-to-date information using pervasive computing of vital signs and motor activity records.

Indexes of the common reed's seed vitality from water-bodies of the Chernobyl exclusive zone

International Nuclear Information System (INIS)

Yavnuk, A.A.; Shevtsova, N.L.; Gudkov, D.I.; Levchenko, Ya.I.

2010-01-01

Investigation of the common reed's seed vitality (vegetation of 2009) from flood-plain water-bodies with different level of radionuclide contamination was carried out. Decrease in indexes of seed's vitality and abnormalities in seed dynamic sprouting was noticed. Dose-response relationship of germination, germinating force, survival rate of seeds of plants was determined. (authors)

Lower periorbital area treatment with Restylane Vital Skinbooster

Directory of Open Access Journals (Sweden)

Denis Souto Valente

2016-09-01

Full Text Available Facial aging along the periocular area has led to the development of new non-surgical therapies. The lower periorbital area is a vital region for facial rejuvenation and several procedures have been studied to treat it, especially procedures with dermal fillers for volume rebuilding. This manuscript aims to describe a filling technique with hyaluronic acid (HA along the superficial layer of the lower periorbital area, presenting its effectiveness and safety. Our assessment was made by autonomous observers with pictures of before and after treatment, rated from 0 (no enhancement to 100 (maximum enhancement. Patients’ self-assessment was also performed using a visual analog scale (VAS based on a 100-mm ruler affording a 0–100 rating. Thirty patients were enrolled in this study. The autonomous observers’ evaluation presented a 78.4 mean improvement rate. Patients’ self-assessments after the treatment were 0% reporting no improvement, 6.7% mild improvement, 23.3% moderate improvement, 66.7% great improvement, and 3.3% maximum improvement. Restylane Vital Skinbooster infiltration at the lower periorbital area proved to be a safe treatment. The described technique is also simple to execute, has a low rate of complications, and produces a high satisfaction rate.

Vital Signs-HIV Care Saves Lives: Viral Suppression is Key

Centers for Disease Control (CDC) Podcasts

This podcast is based on the December 2014 CDC Vital Signs report. For people living with HIV, Viral suppression is critical. By getting tested and taking HIV medicines, individuals living with HIV can achieve very low levels of HIV in the body.

Alternative transport network designs and their implications for intermodal transhipment technologies

OpenAIRE

Woxenius, Johan

2007-01-01

Six principles for operation of the rail part of intermodal rail freight transport systems are described: direct link, corridor, hub-and-spoke, connected hubs, static routes, and dynamic routes. The first part is a theoretical discussion of the characteristics of the transport network designs. The theory is then applied to intermodal freight transport by analysing how each transport network design affects the need for terminal performance. The discussion includes a classification of existing ...

Quality performance-based training enhances safe and effective transport operations

International Nuclear Information System (INIS)

McCall, D.L.

1993-01-01

If the hazardous materials transportation industry is to reduce human error, reduce accidents, and improve its public image, there must be assurance that transportation personnel are properly trained and qualified to perform their jobs in a safe and efficient manner. This training must make them intimately aware of the hazards and risks associated with transport activities, ensure understanding of responsibilities and liabilities unique to their job, and ensure that they can competently perform functional duties vital to safety. To ensure that trained and qualified personnel are on the job, it is essential that the training be performance-based and require trainees to demonstrate functional proficiency. Performance-based training has proven to be a highly effective means of ensuring personnel are qualified to conduct their assignments safely and efficiently. This training is designed around the basic premise that training must be provided that supplies the information necessary for each worker to perform their assigned duties at a predetermined and acceptable level of expertise and skill. (J.P.N.)

CDC Vital Signs–Arthritis in America

Centers for Disease Control (CDC) Podcasts

2017-03-07

This podcast is based on the March 2017 CDC Vital Signs report. Many adults in the United States have arthritis. Learn how to reduce the pain of arthritis, as well as manage the condition.  Created: 3/7/2017 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 3/7/2017.

The Peritelini (Coleoptera: Curculionidae, Entiminae of the Vitale collection

Directory of Open Access Journals (Sweden)

Cosimo Baviera

2016-01-01

Full Text Available The collection of Peritelini (Coleoptera Curculionidae Entiminae currently stored in the Vitale collection of Messina University is an element of great importance for studies of taxonomy and biogeography of these rarely collected weevils. All species are commented in relation to the contributions to this taxonomic group, published on several occasions by the authors.

An evaluation of the adequacy of vital status follow-up in the Hanford worker mortality study

International Nuclear Information System (INIS)

Omohundro, E.L.; Gilbert, E.S.

1993-11-01

The purpose of the study described in this report was to evaluate the completeness of vital status ascertainment in the Hanford worker cohort. Identifying information on 17,708 Hanford workers, including all workers who were monitored for external radiation exposure, employed at least six months at the Hanford site, and whose vital status remains unknown, was submitted to a private search organization, Equifax Government and Special Systems. Equifax then linked Social Security numbers of these workers with death information files. For the period 1945--86 that has been emphasized in recent dose-response analyses of the Hanford data, Equifax ascertained only 12 new deaths, an increase of only 0.2% over deaths that had been ascertained previously. In addition, Equifax ascertained 23 deaths that were judged to be mismatches based on comparison of names and birth-dates on their files and ours; it is shown that this number can be regarded as a rough estimate of the number of deaths missed because workers had incorrect Social Security numbers. Overall the study suggests that the number of deaths missed was not large, but the confidence one can place in this conclusion is limited by the fact that Equifax's ascertainment procedures are not perfect, especially for the period before 1965. In order to evaluate the adequacy of the methods used by Equifax, information on 2,254 Hanford workers who had been previously identified as dead was also submitted. Equifax missed less than 2% of known Hanford deaths occurring in the period 1965--86, but missed about 18% of deaths occurring before 1965. Although recent analyses have focused on the period 1945--86, some analyses have included deaths ascertained using direct linkage with Washington state death files for the period 1987--89

Role of Social Well-Being and Academic Vitality in Predicting the Academic Motivation in Nursing Students

Directory of Open Access Journals (Sweden)

Abbasi M.

2016-02-01

Full Text Available Aims: Due to the studentship stressful factors and challenging clinical conditions and internship, the nursing students undergo emotional exhaustion and academic burnout. The outcomes might, also, negatively affect their academic engagement and functions. The aim of this study was to explain the academic motivation of the nursing students based on the social welfare and vitality.  Instrument & Methods: In the correlational study, the nursing students of Arak University of Medical Sciences were studied in the academic year 2014-15. 210 students were selected via available sampling. Data was collected using academic motivation, Kees social welfare, and academic vitality questionnaires. Data was analyzed by SPSS 18 software using Pearson correlation and multivariate regression tests. Findings: The total mean scores of social welfare, academic motivation, and academic vitality were 98.68±13.21, 40.55±5.98, and 18.58±7.58, respectively. There were significant and positive correlations between social welfare and academic motivation (r=0.183; p<0.001 and the subscales including emotional motivation (r=0.103; p<0.048 and cognitive motivation (r=0.154; p<0.003. Due to the lack of any correlation between academic vitality and academic motivation and its sub-scales, the academic vitality could not predict the academic motivation. Nevertheless, the social welfare could predict 33% of the variance of academic motivation. Conclusion: The social welfare plays an important role to determine the academic motivation of nursing students. Nevertheless, academic vitality plays no role. 

EFFECT OF POSTURAL DRAINAGE POSITIONS ON VITAL PARAMETERS IN ASYMPTOMATIC HEALTHY INDIVIDUALS

Directory of Open Access Journals (Sweden)

Animesh Hazari

2017-09-01

Full Text Available Background: Postural drainage is used exclusively or in combination with other airway clearance techniques in the management of chronic pulmonary diseases. Postural drainage therapy helps to prevent accumulation of secretions in patients who are at high risk for pulmonary complications. It also helps to remove accumulated secretions from the lungs.The role of body positioning on lung function and the clinical implications of postural drainage has been identified in a variety of settings including intensive care units. There is dearth in literature on effects on postural drainage on vital parameters. Thus the objective of the study was to measure the vital parameters at different postural drainage positions in healthy asymptomatic adults. Methods: Twenty healthy subjects participated in the study. The instruments used in the current study included a Pulse oximeter, Sphygmomanometer, Stethoscope, Postural drainage table.The outcome measures of interest were heart rate, respiratoryrate, oxygen saturation, blood pressure and Borg’s scale of rate of perceived exertion. The changes in the vital signs were recorded at different head down titling position of 0°, 15° & 30° in both supine and prone lying positions Results: Statistical significant difference was found for Systolic Blood Pressure in prone lying at different degrees of tilt (p=0.001 and Diastolic Blood Pressure in prone lying (p=0.000. Conclusion: Postural drainage positioning should be given with caution and under proper monitoring as there is a risk of change in the blood pressure even in asymptomatic elderly population. The monitoring of vital signs should be done during the therapy to decrease the risk of complications.

Vital Sign Monitoring and Mobile Phone Usage Detection Using IR-UWB Radar for Intended Use in Car Crash Prevention.

Science.gov (United States)

Leem, Seong Kyu; Khan, Faheem; Cho, Sung Ho

2017-05-30

In order to avoid car crashes, active safety systems are becoming more and more important. Many crashes are caused due to driver drowsiness or mobile phone usage. Detecting the drowsiness of the driver is very important for the safety of a car. Monitoring of vital signs such as respiration rate and heart rate is important to determine the occurrence of driver drowsiness. In this paper, robust vital signs monitoring through impulse radio ultra-wideband (IR-UWB) radar is discussed. We propose a new algorithm that can estimate the vital signs even if there is motion caused by the driving activities. We analyzed the whole fast time vital detection region and found the signals at those fast time locations that have useful information related to the vital signals. We segmented those signals into sub-signals and then constructed the desired vital signal using the correlation method. In this way, the vital signs of the driver can be monitored noninvasively, which can be used by researchers to detect the drowsiness of the driver which is related to the vital signs i.e., respiration and heart rate. In addition, texting on a mobile phone during driving may cause visual, manual or cognitive distraction of the driver. In order to reduce accidents caused by a distracted driver, we proposed an algorithm that can detect perfectly a driver's mobile phone usage even if there are various motions of the driver in the car or changes in background objects. These novel techniques, which monitor vital signs associated with drowsiness and detect phone usage before a driver makes a mistake, may be very helpful in developing techniques for preventing a car crash.

Vital Sign Monitoring and Mobile Phone Usage Detection Using IR-UWB Radar for Intended Use in Car Crash Prevention

Directory of Open Access Journals (Sweden)

Seong Kyu Leem

2017-05-01

Full Text Available In order to avoid car crashes, active safety systems are becoming more and more important. Many crashes are caused due to driver drowsiness or mobile phone usage. Detecting the drowsiness of the driver is very important for the safety of a car. Monitoring of vital signs such as respiration rate and heart rate is important to determine the occurrence of driver drowsiness. In this paper, robust vital signs monitoring through impulse radio ultra-wideband (IR-UWB radar is discussed. We propose a new algorithm that can estimate the vital signs even if there is motion caused by the driving activities. We analyzed the whole fast time vital detection region and found the signals at those fast time locations that have useful information related to the vital signals. We segmented those signals into sub-signals and then constructed the desired vital signal using the correlation method. In this way, the vital signs of the driver can be monitored noninvasively, which can be used by researchers to detect the drowsiness of the driver which is related to the vital signs i.e., respiration and heart rate. In addition, texting on a mobile phone during driving may cause visual, manual or cognitive distraction of the driver. In order to reduce accidents caused by a distracted driver, we proposed an algorithm that can detect perfectly a driver's mobile phone usage even if there are various motions of the driver in the car or changes in background objects. These novel techniques, which monitor vital signs associated with drowsiness and detect phone usage before a driver makes a mistake, may be very helpful in developing techniques for preventing a car crash.

CDC Vital Signs-Daily Pill Can Prevent HIV

Centers for Disease Control (CDC) Podcasts

This podcast is based on the November 24, 2015 CDC Vital Signs report. Preexposure prophylaxis, or PrEP, is a daily medicine that can be used to prevent getting HIV. PrEP is for people who don’t have HIV but who are at very high risk for getting it from sex or injection drug use. Unfortunately, many people who can benefit from PrEP aren’t taking it.

CDC Vital Signs-E-cigarette Ads and Youth

Centers for Disease Control (CDC) Podcasts

This podcast is based on the January 2016 CDC Vital Signs report. Most electronic cigarettes, or e-cigarettes, contain nicotine, which is highly addictive and may harm brain development. More than 18 million middle and high school students were exposed to e-cigarette ads. Exposure to these ads may be contributing to an increase in e-cigarette use among youth. Learn what can be done to keep our youth safe and healthy.

Explanatory models for homeopathy: from the vital force to the current paradigm.

Science.gov (United States)

Waisse, Silvia; Bonamin, Leoni Villano

2016-08-01

Facing claims for and against the scientific status of homeopathy, one is entitled to ask: is there a scientific model for homeopathy? In this study we reconstructed the model put forward by Hahnemann. The results showed that it was essentially based on the assumption of a 'vital force' exclusive to living beings. While the vital force was a basic element of 18th-century science, the existence of such a sui generis force of nature was refuted with the formulation of the law of the conservation of energy by mid-19th century. As a function of that fact for homeopathic theory, we discuss the history of the rise and demise of the theory of the vital force from the last quarter of the 18th century to 1830. Finally, we call the attention to the paradigm shift biology underwent starting at the end of the 19th century as the framework for contemporary views on the functioning of living beings and consequently, of the effects of pharmacological agents on them. Copyright © 2016 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

Optimal transportation networks models and theory

CERN Document Server

Bernot, Marc; Morel, Jean-Michel

2009-01-01

The transportation problem can be formalized as the problem of finding the optimal way to transport a given measure into another with the same mass. In contrast to the Monge-Kantorovitch problem, recent approaches model the branched structure of such supply networks as minima of an energy functional whose essential feature is to favour wide roads. Such a branched structure is observable in ground transportation networks, in draining and irrigation systems, in electrical power supply systems and in natural counterparts such as blood vessels or the branches of trees. These lectures provide mathematical proof of several existence, structure and regularity properties empirically observed in transportation networks. The link with previous discrete physical models of irrigation and erosion models in geomorphology and with discrete telecommunication and transportation models is discussed. It will be mathematically proven that the majority fit in the simple model sketched in this volume.

Interconnection and power transportation networks: operation; Reseaux d'interconnexion et de transport: fonctionnement

Energy Technology Data Exchange (ETDEWEB)

Bornard, P. [Reseau de Transport d' Electricite (RTE), Div. Systeme Electrique, 92 - Paris la Defense (France); Pavard, M. [Electricite de France (EDF), 75 - Paris (France); Testud, G. [Reseau de Transport d' Electricite (RTE), Dept. Exploitation du Systeme Electrique, 92 - Paris la Defense (France)

2005-10-01

For economical or technical reasons, the power generation units are in general grouped together in the same geographical areas, while the consumption points are much more dispersed. The power transportation and interconnection networks ensure the link between the big generation areas and the big consumption areas, and also with other foreign networks. The network manager must keep the balance between the available offer and the potential demand and ensures the transit of energy between the production units and the end-users with respecting the contractual voltage and frequency ranges. Incidents must be mastered to limit the inconvenience to users and to avoid the complete collapse of the power transportation system. This article describes the operation of such systems: 1 - problems linked with networks operation; 2 - transits distribution: general problem, transmissible power in a power line, voltage drop, calculations of power distributions; 3 - voltage and frequency adjustments; 4 - operation in disturbed regime: mastery of common incidents, mechanisms of major incidents (operation of a power system in strongly disturbed regime), protection of the power system, recovery; 5 - conclusion. (J.S.)

Community Vitality: The Role of Community-Level Resilience Adaptation and Innovation in Sustainable Development

Directory of Open Access Journals (Sweden)

Lenore Newman

2010-01-01

Full Text Available Community level action towards sustainable development has emerged as a key scale of intervention in the effort to address our many serious environmental issues. This is hindered by the large-scale destruction of both urban neighbourhoods and rural villages in the second half of the twentieth century. Communities, whether they are small or large, hubs of experimentation or loci of traditional techniques and methods, can be said to have a level of community vitality that acts as a site of resilience, adaptation and innovation in the face of environmental challenges. This paper outlines how community vitality acts as a cornerstone of sustainable development and suggests some courses for future research. A meta-case analysis of thirty-five Canadian communities reveals the characteristics of community vitality emerging from sustainable development experiments and its relationship to resilience, applied specifically to community development.

Engineering economics and finance for transportation infrastructure

CERN Document Server

Prassas, Elena S

2013-01-01

Transportation infrastructure is often referred to as society’s bloodstream.  It allows for the movement of people and goods to provide the ability to optimize the production and distribution of goods in an effective and efficient manner, and to provide personal opportunities for employment, recreation, education, health care, and other vital activities.   At the same time, the costs to provide, maintain, and operate this complex infrastructure are enormous.  Because so much of the economic resources to be invested come from public funds, it is critical that expenditures are made in a manner that provides society with the best possible return on the investment.  Further, it is important that sufficient investment is made available, and the costs of the investment are equitably borne by taxpayers.   This textbook provides a fundamental overview of the application of engineering economic principles to transportation infrastructure investments.  Basic theory is presented and illustrated with examples spe...

Formal Vulnerability Assessment of a maritime transportation system

International Nuclear Information System (INIS)

Berle, Oyvind; Asbjornslett, Bjorn Egil; Rice, James B.

2011-01-01

World trade increasingly relies on longer, larger and more complex supply chains, where maritime transportation is a vital backbone of such operations. Long and complex supply chain systems are more prone to being vulnerable, though through reviews, no specific methods have been found to assess vulnerabilities of a maritime transportation system. Most existing supply chain risk assessment frameworks require risks to be foreseen to be mitigated, rather than giving transportation systems the ability to cope with unforeseen threats and hazards. In assessing cost-efficiency, societal vulnerability versus industrial cost of measures should be included. This conceptual paper presents a structured Formal Vulnerability Assessment (FVA) methodology, seeking to transfer the safety-oriented Formal Safety Assessment (FSA) framework into the domain of maritime supply chain vulnerability. To do so, the following two alterations are made: (1) The focus of the assessment is defined to ensure the ability of the transportation to serve as a throughput mechanism of goods, and to survive and recover from disruptive events. (2) To cope with low-frequency high-impact disruptive scenarios that were not necessarily foreseen, two parallel tracks of risk assessments need to be pursued-the cause-focused risk assessment as in the FSA, and a consequence-focused failure mode approach.

A simple intervention improves the recording of vital signs in children presenting to the emergency department.

Science.gov (United States)

Bird, C; Shea, A; Michie, C A; George, G

2009-10-01

Vital signs are often not documented in paediatric patients at triage. This study was conducted to find out whether the use of a small, laminated aide memoire and a short teaching session might improve this situation. A preliminary audit of the measurement of vital signs in 106 children aged less than 6 years was carried out in a district general hospital emergency department (ED). A small card illustrating normal values for these was then distributed-this could be attached to staff identity cards. At the same time doctors and nursing staff were given a teaching session on the importance of these measures. The audit was then repeated in a further 106 children. There was significant improvement in recording of all vital signs with the exception of blood pressure and temperature. A low-cost card together with a short period of training offers a useful strategy to improve the rate of documentation of vital signs in children presenting to the ED.

Sintering boat transport system for the SAF line

International Nuclear Information System (INIS)

Egli, W.; Bogart, R.L.

1983-10-01

The Secure Automated Fabrication (SAF) line will be a remotely operated process for the manufacture of breeder reactor fuel pins. The sintering boat transport system will service the pellet operations. Since the Boat Transport System will be the major link between several subsystem operations, reliability and ease of maintenance are prime requirements for the design. A prototypic version of the Boat Transport System was designed, built and tested to verify the operability of the selected approach. Extensive testing provided valuable input to the final design and substantiated the soundness of the concept

Economic competitiveness : performance measures for transportation : review of literature and best practices.

Science.gov (United States)

2008-11-01

The New York State Department of Transportation (NYSDOT) is developing a comprehensive set of measures that link investments in transportation to the general economic performance of the New York State Economy. The agency would like to understand in p...

Os postulados de Nightingale e Semmelweis: poder/vital e prevenção/contágio como estratégias para a evitabilidade das infecções Los postulados de Nightingale y Semmelweis: energía vital/vida y prevención/contágio como estrategias para evitar las infecciones Nightingale's and Semmelweis' postulates: vital power and contagion prevention as strategies to avoid infections

Directory of Open Access Journals (Sweden)

Telma Elisa Carraro

2004-08-01

Full Text Available Trata-se de pesquisa qualitativa, que utilizou a observação como técnica para coleta de dados, tendo como guia um instrumento elaborado a partir de postulados de Florence Nightingale e Ignaz Phillip Semmelweis: poder vital/vida e prevenção/contágio. Registra breve histórico sobre o controle de infecções, destacando o enfoque prevenção/contágio. Discorre sobre o postulado poder vital/vida, apresentando e discutindo os componentes da assistência de Enfermagem dele decorrentes para o desenvolvimento da assistência. Recomenda que se considere articuladamente as vertentes - Poder Vital/Vida e Prevenção/Contágio - como estratégias para a evitabilidade das infecções.Esta investigación cualitativa utilizó la observación como técnica de recolección de datos, guiándose por un instrumento basado en los postulados de Florence Nightingale e Ignaz Phillip Semmelweis: energía vital/vida y prevención/contagio. Presenta un breve histórico acerca del control de infección, destacando el enfoque prevención/contagio. Habla sobre el postulado energía vital/vida, presentando y discutiendo los componentes de la asistencia de enfermería que se desprenden de él para el desarrollo de la asistencia. Concluye recomendando que se considere articuladamente las vertientes energía vital/vida y prevención/contagio como estrategia para evitar las infecciones.This qualitative research used observation as a data collection technique, guided by an instrument elaborated on the basis of Nightingale and Semmelweis' postulates: vital power/life and prevention/contagion. A brief history of infection control is offered from the focus of prevention/contagion. The postulate vital power/life is discussed, presenting the nursing care components deriving from it with a view to care development. This study recommends that both postulates - vital power/life and prevention/contagion - be considered in an articulated way as strategies to avoid infections.

Fiber-Optic Communication Links Suitable for On-Board Use in Modern Aircraft

Science.gov (United States)

Nguyen, Hung; Ngo, Duc; Alam, Mohammad F.; Atiquzzaman, Mohammed; Sluse, James; Slaveski, Filip

2004-01-01

The role of the Advanced Air Transportation Technologies program undertaken at the NASA Glenn Research Centers has been focused mainly on the improvement of air transportation safety, with particular emphasis on air transportation communication systems in on-board aircraft. The conventional solutions for digital optical communications systems specifically designed for local/metro area networks are, unfortunately, not capable of transporting the microwave and millimeter RF signals used in avionics systems. Optical networks capable of transporting RF signals are substantially different from the standard digital optical communications systems. The objective of this paper is to identify a number of different communication link architectures for RF/fiber optic transmission using a single backbone fiber for carrying VHF and UHF RF signals in the aircraft. To support these architectures, two approaches derived from both hybrid RF-optical and all-optical processing methodologies are discussed with single and multiple antennas for explicitly transporting VHF and UHF signals, while the relative merits and demerits of each architecture are also addressed. Furthermore, the experimental results of wavelength division multiplexing (WDM) link architecture from our test-bed platform, configured for aircraft environment to support simultaneous transmission of multiple RF signals over a single optical fiber, exhibit no appreciable signal degradation at wavelengths of both 1330 and 1550 nm, respectively. Our measurements of signal to noise ratio carried out for the transmission of FM and AM analog modulated signals at these wavelengths indicate that WDM is a fiber optic technology which is potentially suitable for avionics applications.

Synthesis and inhibitory evaluation of 3-linked imipramines for the exploration of the S2 site of the human serotonin transporter

DEFF Research Database (Denmark)

Brinkø, Anne; Larsen, Maja Thim; Koldsø, Heidi

2016-01-01

The human serotonin transporter is the primary target of several antidepressant drugs, and the importance of a primary, high affinity binding site (S1) for antidepressant binding is well documented. The existence of a lower affinity, secondary binding site (S2) has, however, been debated. Herein we...... of the positional relationship between the S1 and S2 sites. The computer simulations suggested that the S2 site does indeed exist although with lower affinity for imipramine than observed within the S1 site. Additionally, it was possible to dock the 3-linked imipramine analogs into positions which occupy the S1...... and the S2 site simultaneously. The structure activity relationship study showed that the shortest ligands were the most potent, and mutations enlarging the proposed S2 site were found to affect the larger ligands positively, while the smaller ligands were mostly unaffected....

Causal pathways linking environmental change with health behaviour change: Natural experimental study of new transport infrastructure and cycling to work.

Science.gov (United States)

Prins, R G; Panter, J; Heinen, E; Griffin, S J; Ogilvie, D B

2016-06-01

Mechanisms linking changes to the environment with changes in physical activity are poorly understood. Insights into mechanisms of interventions can help strengthen causal attribution and improve understanding of divergent response patterns. We examined the causal pathways linking exposure to new transport infrastructure with changes in cycling to work. We used baseline (2009) and follow-up (2012) data (N=469) from the Commuting and Health in Cambridge natural experimental study (Cambridge, UK). Exposure to new infrastructure in the form of the Cambridgeshire Guided Busway was defined using residential proximity. Mediators studied were changes in perceptions of the route to work, theory of planned behaviour constructs and self-reported use of the new infrastructure. Outcomes were modelled as an increase, decrease or no change in weekly cycle commuting time. We used regression analyses to identify combinations of mediators forming potential pathways between exposure and outcome. We then tested these pathways in a path model and stratified analyses by baseline level of active commuting. We identified changes in perceptions of the route to work, and use of the cycle path, as potential mediators. Of these potential mediators, only use of the path significantly explained (85%) the effect of the infrastructure in increasing cycling. Path use also explained a decrease in cycling among more active commuters. The findings strengthen the causal argument that changing the environment led to changes in health-related behaviour via use of the new infrastructure, but also show how some commuters may have spent less time cycling as a result. Copyright © 2016. Published by Elsevier Inc.

CDC Vital Signs–Dental Sealants Prevent Cavities

Centers for Disease Control (CDC) Podcasts

This podcast is based on the October 2016 CDC Vital Signs report. Dental sealants, applied soon after a child's permanent molars come in, can protect against cavities for up to nine years. Applying sealants in schools for low-income children could save millions in dental treatment costs.

TRANSPORT OF WASTE SIMULANTS IN PJM VENT LINES

Energy Technology Data Exchange (ETDEWEB)

Qureshi, Z

2007-02-21

The experimental work was conducted to determine whether there is a potential for waste simulant to transport or 'creep' up the air link line and contaminate the pulse jet vent system, and possibly cause long term restriction of the air link line. Additionally, if simulant creep occurred, establish operating parameters for washing down the line. The amount of the addition of flush fluids and mixer downtime must be quantified.

Sustainable transport strategy for promoting zero-emission electric scooters in Taiwan

Energy Technology Data Exchange (ETDEWEB)

Hwang, Jenn Jiang [Department of Greenergy, National University of Tainan, Tainan 700 (China)

2010-06-15

In Taiwan, the government considers the zero-emission scooters to be a sustainable form of transport like walking, cycling and public transport, which play a vital role to support sustainable urban mobility. Therefore, the development of zero-emission scooters is an important strategy in constructing the sustainable transport network of Taiwan. It is also the government's priorities about the policy of emission-reduction and energy-conservation in the transportation sector. Recently, Taiwan launched a new program for subsidy of purchasing zero-emission scooters, which aimed to shift the petroleum-powered scooters to the electric scooters. The present paper is providing an update review of the promotional programs in developing zero-emission scooters in Taiwan. It introduces the status of the establishment and progress of policy, standards, subsidies to users and manufacturers, practice infrastructure, and technology development. Moreover, the contribution of replacing petrol scooters by zero-emission scooters such as battery-powered electric scooters and fuel cell scooters to reduction in greenhouse gas (GHG) emission and improvement in energy efficiency is evaluated. (author)

Faculty Vitality in "Different Worlds": The View from Three Academic Areas. ASHE 1988 Annual Meeting Paper.

Science.gov (United States)

Baldwin, Roger G.

The professional lives of "vital" professors in the areas of arts and humanities, mathematics and natural sciences, and the social sciences are examined, and common and subject-area specific factors (such as attributes, activities, and sources of support) closely associated with faculty vitality are identified. Subjects were chosen from…

CDC Vital Signs–Preventing Stroke Deaths

Centers for Disease Control (CDC) Podcasts

2017-09-06

This podcast is based on the September 2017 CDC Vital Signs report. Each year, more than 140,000 people die and many survivors face disability. Eighty percent of strokes are preventable. Learn the signs of stroke and how to prevent them.  Created: 9/6/2017 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/6/2017.

Vitality detection in personal authentication systems using fingerprints

OpenAIRE

Coli, Pietro

2008-01-01

Fingerprints are considered as the sign of each human being, and this has contributed the development of biometric applications based on such features. Since 2002, an important vulnerability has been shown: it is possible to deceive fingerprint scanners through artificial replicas of fingertips. In order to address this shortcoming it is need to recognize a spoofing attempt with artificial fingers looking for some “life signs” each time an user submit a fingerprint (vitality detection problem...

The vulnerability of the global container shipping network to targeted link disruption

CSIR Research Space (South Africa)

Viljoen, NM

2016-11-01

Full Text Available transport, complex network theory has had limited application in studying the vulnerability of maritime networks. This study uses targeted link disruption to investigate the strategy specific vulnerability of the network. Although nodal infrastructure...

Critical currents and weak links in melt textured R123

International Nuclear Information System (INIS)

Veal, B. W.; Zhang, H.; Claus, H.; Chen, L.; Paulikas, A. P.; Koshelev, A.; Crabtree, G. W.

2000-01-01

Weak link behavior is studied, using magnetization and Hall probe measurements of ring samples, in welded melt-textured R123 monoliths and in dual-seeded samples with disoriented domains. Techniques for welding samples yield transport currents across the junction that are in excess of 10 4 A/cm 2

Effectiveness of a worksite lifestyle intervention on vitality, work engagement, productivity, and sick leave: results of a randomized controlled trial.

Science.gov (United States)

Strijk, Jorien E; Proper, Karin I; van Mechelen, Willem; van der Beek, Allard J

2013-01-01

A worksite lifestyle intervention aiming to improve lifestyle behaviors could be an effective tool to keep older workers vital, and thereby prolong their labor participation. Therefore, this study evaluates the effectiveness of such an intervention on vitality, work engagement, productivity and sick leave. In a randomized controlled trial design, 367 workers (control group: N=363) received a 6-month intervention, which included two weekly guided group sessions: one yoga and one workout, as well as one weekly session of aerobic exercising, without face-to-face instruction, and three individual coach visits aimed at changing workers' lifestyle behavior by goal setting, feedback, and problem-solving strategies. Furthermore, free fruit was provided at the guided sessions. Data on work-related vitality (UWES vitality scale), general vitality (RAND-36 vitality scale), work engagement (UWES), productivity (single item scoring 0-10), and sick leave (yes/no past 3 months) were collected using questionnaires at baseline (N=730), and at 6- (N=575) and 12-months (N=500) follow-up. Effects were analyzed according to the intention-to-treat principle with complete cases (N=500) and imputed data (N=730). There were no significant differences in vitality, work engagement, productivity, and sick leave between the intervention and control group workers after either 6- and 12-months follow-up. Yoga and workout subgroup analyses showed a 12-month favorable effect on work-related vitality [β=0.14, 95% confidence interval (95% CI) 0.04-0.28] and general vitality (β=2.9, 95% CI 0.02-5.9) among high yoga compliers. For high workout compliers, this positive trend was also seen, but it was not statistically significant. Implementation of worksite yoga facilities could be a useful strategy to promote vitality-related work outcomes, but only if high compliance can be maximized. Therefore, impeding factors for participation should be investigated in more detail in future research.

Pulpal inflammation after vital tooth bleaching with 38% hydrogen peroxide

Directory of Open Access Journals (Sweden)

Ardiny Andriani

2012-06-01

Full Text Available Background: In-office vital tooth bleaching is a treatment to remove tooth stains. Tooth sensitivity is one of side effect commonly complained by patients receiving this treatment. Purpose: The aim of this study was to examine histological inflammatory cells infiltration of dental pulp after application of 38% H2O2 as a vital tooth bleaching agent. Methods: Under informed consent, a total of 15 premolars from 8 healthy subjects scheduled for orthodontic extraction were used in this study. Thirty eight percent H2O2 was applied on the buccal surface of the treated group. The treated teeth were extracted after 1 hour, 5, 8, and 15 days. All specimens were embedded in paraffin wax, sectioned serially and stained with Hematoxyllin Eosin. Histological specimens were then observed under a light microscope. Results: All treated groups showed a slight disorganization of odontoblasts layer and slight inflammation in the pulp tissue adjacent to the 38% H2O2 application site. The number of polymorphonuclear leukocytes (PMN had increased significantly 1 hour after application of 38% H2O2 (p<0.05, while macrophages had significantly increased 5 days after the application (p<0.05. The most intense PMN and macrophages infiltration was found 5 days after the application and gradually decreased 8 days after application of38% H2O2. Conclusion: Application of 38% H2O2 as a vital tooth bleaching agent induces acute inflammation in human dental pulp; however, the inflammation will decrease 8 days after the application.Latar belakang: Perawatan pemutihan gigi vital metode in-office merupakan tindakan untuk menghilangkan pewarnaan pada gigi. Salah satu efek samping yang sering dikeluhkan oleh pasien yang menjalani perawatan ini adalah sensitivitas gigi. Tujuan: Penelitian ini bertujuan untuk mengamati infiltrasi sel inflamasi pada pulpa gigi setelah aplikasi H2O2 38% sebagai bahan pemutih gigi. Metode: Sampel penelitian ini berupa 15 gigi premolar yang berasal dari 8

The challenges of transportation/traffic statistics in Japan and directions for the future

Directory of Open Access Journals (Sweden)

Shigeru Kawasaki

2015-07-01

Full Text Available In order to respond to new challenges in transportation and traffic problems, it is essential to enhance statistics in this field that provides the basis for policy researches. Many of the statistics in this field in Japan consist of “official statistics” created by the government. This paper gives a review of the current status of transportation and traffic statistics (hereinafter called “transportation statistics” in short in Japan. Furthermore, the paper discusses challenges in such statistics in the new environment and the direction that statistics that should take in the future. For Japan’s transportation statistics to play vital roles in more sophisticated analyses, it is necessary to improve the environment that facilitates the use of microdata for analysis. It is also necessary to establish an environment where big data can be more easily used for compilation of official statistics and performing policy researches. To achieve this end, close cooperation among the government, academia, and businesses will be essential.

METscout: a pathfinder exploring the landscape of metabolites, enzymes and transporters.

Science.gov (United States)

Geffers, Lars; Tetzlaff, Benjamin; Cui, Xiao; Yan, Jun; Eichele, Gregor

2013-01-01

METscout (http://metscout.mpg.de) brings together metabolism and gene expression landscapes. It is a MySQL relational database linking biochemical pathway information with 3D patterns of gene expression determined by robotic in situ hybridization in the E14.5 mouse embryo. The sites of expression of ∼1500 metabolic enzymes and of ∼350 solute carriers (SLCs) were included and are accessible as single cell resolution images and in the form of semi-quantitative image abstractions. METscout provides several graphical web-interfaces allowing navigation through complex anatomical and metabolic information. Specifically, the database shows where in the organism each of the many metabolic reactions take place and where SLCs transport metabolites. To link enzymatic reactions and transport, the KEGG metabolic reaction network was extended to include metabolite transport. This network in conjunction with spatial expression pattern of the network genes allows for a tracing of metabolic reactions and transport processes across the entire body of the embryo.

Simultaneous vitality and DNA-fragmentation measurement in spermatozoa of smokers and non-smokers.

Science.gov (United States)

De Bantel, A; Fleury-Feith, J; Poirot, C; Berthaut, I; Garcin, C; Landais, P; Ravel, C

2015-03-01

Because cigarette smoke is a powerful ROS producer, we hypothesized that the spermatozoa of smokers would be more at risk of having increased DNA fragmentation than spermatozoa of non-smoking men. A cross-sectional study was performed on consenting smokers and non-smokers, consulting in an infertility clinic for routine sperm analysis. The application of a novel TUNEL assay coupled to a vitality marker, LIVE/DEAD®, allowed both DNA fragmentation and viability measurement within spermatozoa of participants to be analyzed by flow cytometry. The coupled vitality-DNA fragmentation analysis revealed that non-smokers and smokers, respectively presented medians of 3.6% [0.6-36.8] and 3.3% [0.9-9.6] DNA fragmented spermatozoa among the living spermatozoa population (P > 0.05). No deleterious effect of smoking on spermatozoa was found in our study. More studies concerning potential mutagenic capacities of cigarette smoke on spermatozoa are necessary. In addition, the coupled vitality-DNA fragmentation analysis may orient Assisted Reproductive Technology teams when confronted with patients having a high percentage of DNA-fragmented living spermatozoa. © 2014 International Clinical Cytometry Society.

Pediatric Vital Sign Distribution Derived From a Multi-Centered Emergency Department Database

Directory of Open Access Journals (Sweden)

Robert J. Sepanski

2018-03-01

Full Text Available BackgroundWe hypothesized that current vital sign thresholds used in pediatric emergency department (ED screening tools do not reflect observed vital signs in this population. We analyzed a large multi-centered database to develop heart rate (HR and respiratory rate centile rankings and z-scores that could be incorporated into electronic health record ED screening tools and we compared our derived centiles to previously published centiles and Pediatric Advanced Life Support (PALS vital sign thresholds.MethodsInitial HR and respiratory rate data entered into the Cerner™ electronic health record at 169 participating hospitals’ ED over 5 years (2009 through 2013 as part of routine care were analyzed. Analysis was restricted to non-admitted children (0 to <18 years. Centile curves and z-scores were developed using generalized additive models for location, scale, and shape. A split-sample validation using two-thirds of the sample was compared with the remaining one-third. Centile values were compared with results from previous studies and guidelines.ResultsHR and RR centiles and z-scores were determined from ~1.2 million records. Empirical 95th centiles for HR and respiratory rate were higher than previously published results and both deviated from PALS guideline recommendations.ConclusionHeart and respiratory rate centiles derived from a large real-world non-hospitalized ED pediatric population can inform the modification of electronic and paper-based screening tools to stratify children by the degree of deviation from normal for age rather than dichotomizing children into groups having “normal” versus “abnormal” vital signs. Furthermore, these centiles also may be useful in paper-based screening tools and bedside alarm limits for children in areas other than the ED and may establish improved alarm limits for bedside monitors.

Assessing links between energy consumption, freight transport, and economic growth: evidence from dynamic simultaneous equation models.

Science.gov (United States)

Nasreen, Samia; Saidi, Samir; Ozturk, Ilhan

2018-06-01

We investigate this study to examine the relationship between economic growth, freight transport, and energy consumption for 63 developing countries over the period of 1990-2016. In order to make the panel data analysis more homogeneous, we apply the income level of countries to divide the global panel into three sub-panels, namely, lower-middle income countries (LMIC), upper-middle income countries (UMIC), and high-income countries (HIC). Using the generalized method of moments (GMM), the results prove evidence of bidirectional causal relationship between economic growth and freight transport for all selected panels and between economic growth and energy consumption for the high- and upper-middle income panels. For the lower-middle income panel, the causality is unidirectional running from energy consumption to economic growth. Also, the results indicate that the relationship between freight transport and energy use is bidirectional for the high-income countries and unidirectional from freight transport to energy consumption for the upper-middle and lower-middle income countries. Empirical evidence demonstrates the importance of energy for economic activity and rejects the neo-classical assumption that energy is neutral for growth. An important policy recommendation is that there is need of advancements in vehicle technology which can reduce energy intensity from transport sector and improve the energy efficiency in transport activity which in turn allows a greater positive role of transport in global economic activity.

Immunomodulation by LongoVital in patients with recurrent aphthous ulceration

DEFF Research Database (Denmark)

Pedersen, A; Klausen, B; Hougen, H P

1990-01-01

LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. Peripheral lymphocyte subsets: T-helper/CD4 (OKT4+) and T-suppressor/cytotoxic/CD8 (OKT8+) were studied quantitatively in 31 otherwise healthy patients with minor recurrent aphthous...

Uncertainty calculation in transport models and forecasts

DEFF Research Database (Denmark)

Manzo, Stefano; Prato, Carlo Giacomo

Transport projects and policy evaluations are often based on transport model output, i.e. traffic flows and derived effects. However, literature has shown that there is often a considerable difference between forecasted and observed traffic flows. This difference causes misallocation of (public...... implemented by using an approach based on stochastic techniques (Monte Carlo simulation and Bootstrap re-sampling) or scenario analysis combined with model sensitivity tests. Two transport models are used as case studies: the Næstved model and the Danish National Transport Model. 3 The first paper...... in a four-stage transport model related to different variable distributions (to be used in a Monte Carlo simulation procedure), assignment procedures and levels of congestion, at both the link and the network level. The analysis used as case study the Næstved model, referring to the Danish town of Næstved2...

Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5).

Science.gov (United States)

Scalise, Mariafrancesca; Pochini, Lorena; Panni, Simona; Pingitore, Piero; Hedfalk, Kristina; Indiveri, Cesare

2014-11-01

The kinetic mechanism of the transport catalyzed by the human glutamine/neutral amino acid transporter hASCT2 over-expressed in P. pastoris was determined in proteoliposomes by pseudo-bi-substrate kinetic analysis of the Na(+)-glutamineex/glutaminein transport reaction. A random simultaneous mechanism resulted from the experimental analysis. Purified functional hASCT2 was chemically cross-linked to a stable dimeric form. The oligomeric structure correlated well with the kinetic mechanism of transport. Half-saturation constants (Km) of the transporter for the other substrates Ala, Ser, Asn and Thr were measured both on the external and internal side. External Km were much lower than the internal ones confirming the asymmetry of the transporter. The electric nature of the transport reaction was determined imposing a negative inside membrane potential generated by K(+) gradients in the presence of valinomycin. The transport reaction resulted to be electrogenic and the electrogenicity originated from external Na(+). Internal Na(+) exerted a stimulatory effect on the transport activity which could be explained by a regulatory, not a counter-transport, effect. Native and deglycosylated hASCT2 extracted from HeLa showed the same transport features demonstrating that the glycosyl moiety has no role in transport function. Both in vitro and in vivo interactions of hASCT2 with the scaffold protein PDZK1 were revealed.

A framework for the economic analysis of data collection methods for vital statistics.

Science.gov (United States)

Jimenez-Soto, Eliana; Hodge, Andrew; Nguyen, Kim-Huong; Dettrick, Zoe; Lopez, Alan D

2014-01-01

Over recent years there has been a strong movement towards the improvement of vital statistics and other types of health data that inform evidence-based policies. Collecting such data is not cost free. To date there is no systematic framework to guide investment decisions on methods of data collection for vital statistics or health information in general. We developed a framework to systematically assess the comparative costs and outcomes/benefits of the various data methods for collecting vital statistics. The proposed framework is four-pronged and utilises two major economic approaches to systematically assess the available data collection methods: cost-effectiveness analysis and efficiency analysis. We built a stylised example of a hypothetical low-income country to perform a simulation exercise in order to illustrate an application of the framework. Using simulated data, the results from the stylised example show that the rankings of the data collection methods are not affected by the use of either cost-effectiveness or efficiency analysis. However, the rankings are affected by how quantities are measured. There have been several calls for global improvements in collecting useable data, including vital statistics, from health information systems to inform public health policies. Ours is the first study that proposes a systematic framework to assist countries undertake an economic evaluation of DCMs. Despite numerous challenges, we demonstrate that a systematic assessment of outputs and costs of DCMs is not only necessary, but also feasible. The proposed framework is general enough to be easily extended to other areas of health information.

Transportation into narrative worlds and the motivation to change health-related behavior

NARCIS (Netherlands)

Gebbers, Timon; de Wit, J.B.F.; Appel, Markus

2017-01-01

Stories are considered to be a potent means to change health-related attitudes, beliefs, and behavior because of recipients’ transportation into the narrative world. Little emphasis, however, has been given to the link between transportation and process variables that are pertinent to health

A Monte Carlo burnup code linking MCNP and REBUS

International Nuclear Information System (INIS)

Hanan, N.A.; Olson, A.P.; Pond, R.B.; Matos, J.E.

1998-01-01

The REBUS-3 burnup code, used in the anl RERTR Program, is a very general code that uses diffusion theory (DIF3D) to obtain the fluxes required for reactor burnup analyses. Diffusion theory works well for most reactors. However, to include the effects of exact geometry and strong absorbers that are difficult to model using diffusion theory, a Monte Carlo method is required. MCNP, a general-purpose, generalized-geometry, time-dependent, Monte Carlo transport code, is the most widely used Monte Carlo code. This paper presents a linking of the MCNP code and the REBUS burnup code to perform these difficult analyses. The linked code will permit the use of the full capabilities of REBUS which include non-equilibrium and equilibrium burnup analyses. Results of burnup analyses using this new linked code are also presented. (author)

A Monte Carlo burnup code linking MCNP and REBUS

International Nuclear Information System (INIS)

Hanan, N. A.

1998-01-01

The REBUS-3 burnup code, used in the ANL RERTR Program, is a very general code that uses diffusion theory (DIF3D) to obtain the fluxes required for reactor burnup analyses. Diffusion theory works well for most reactors. However, to include the effects of exact geometry and strong absorbers that are difficult to model using diffusion theory, a Monte Carlo method is required. MCNP, a general-purpose, generalized-geometry, time-dependent, Monte Carlo transport code, is the most widely used Monte Carlo code. This paper presents a linking of the MCNP code and the REBUS burnup code to perform these difficult burnup analyses. The linked code will permit the use of the full capabilities of REBUS which include non-equilibrium and equilibrium burnup analyses. Results of burnup analyses using this new linked code are also presented

Integrated land-use and transport modelling using OTP to determine lowest cost trips

CSIR Research Space (South Africa)

Van Heerden, Q

2015-10-01

Full Text Available This presentation discusses the link between economic infrastructure, that includes transport, and social infrastructure that includes social well-being and the basic necessities of people. It shows how transport models and urban models influence...

Attitudes of final-year dental students to bleaching of vital and non-vital teeth in Cardiff, Cork, and Malmö.

Science.gov (United States)

Hatherell, S; Lynch, C D; Burke, F M; Ericson, D; Gilmour, A S M

2011-04-01

The aim of this study was to determine attitudes of final-year dental students in Cardiff, Cork and Malmö towards tooth whitening. Following receipt of ethical approval, pre-piloted questionnaires were distributed to final-year dental students in Cork, Cardiff, and Malmö as close as possible to graduation. The questionnaire sought information relating to various opinions and attitudes towards the use of bleaching techniques including safety of bleaching, confidence in the provision of bleaching, recommendations to patients, teaching received, awareness of restrictions on the use of bleaching products and management of simulated clinical scenarios. Eighty three per cent (n = 116) of questionnaires were returned. Cork dental students had the most didactic teaching (2-h vital, 1-h non-vital bleaching) compared to Cardiff or Malmö students (0 h each). More Cork students regarded bleaching as safe (76%, n = 28) than Cardiff (70%, n = 32) or Malmö (36%, n = 12) students. More than 50% of Cork students feel they know enough about bleaching to provide it in practice, significantly more than Cardiff (Cork; 82% (n = 27) Malmö; 76% (n = 35) Cardiff). In simulated clinical scenarios, more Cork students would propose bleaching treatments (89%n = 33) than Malmö (64%n = 21) or Cardiff (48%n= 22) students. Variations exist in the attitudes and approaches of three European dental schools towards bleaching. Dental students need to be best prepared to meet the needs of their future patients. © 2010 Blackwell Publishing Ltd.

A Fuzzy mathematical model to estimate the effects of global warming on the vitality of Laelia purpurata orchids.

Science.gov (United States)

Putti, Fernando Ferrari; Filho, Luis Roberto Almeida Gabriel; Gabriel, Camila Pires Cremasco; Neto, Alfredo Bonini; Bonini, Carolina Dos Santos Batista; Rodrigues Dos Reis, André

2017-06-01

This study aimed to develop a fuzzy mathematical model to estimate the impacts of global warming on the vitality of Laelia purpurata growing in different Brazilian environmental conditions. In order to develop the mathematical model was considered as intrinsic factors the parameters: temperature, humidity and shade conditions to determine the vitality of plants. Fuzzy model results could accurately predict the optimal conditions for cultivation of Laelia purpurata in several sites of Brazil. Based on fuzzy model results, we found that higher temperatures and lacking of properly shading can reduce the vitality of orchids. Fuzzy mathematical model could precisely detect the effect of higher temperatures causing damages on vitality of plants as a consequence of global warming. Copyright © 2017 Elsevier Inc. All rights reserved.

Monitoring and analysis of vital signs of a patient through a multi-agent application system

Directory of Open Access Journals (Sweden)

Daniel HERNÁNDEZ DE LA IGLESIA

2016-06-01

Full Text Available In the medical environment, the clinical study of the most basic vital signs of a patient represents the simplest and most effective way to detect and monitor health problems. There are many diseases that can be diagnosed and controlled through regular monitoring of these medical data. The purpose of this study is to develop a monitoring and tracking system for the various vital signs of a patient. In particular, this work focuses on the design of a multi-agent architecture composed of virtual organizations with capabilities to integrate different medical sensors on an open, low-cost hardware platform. This system integrates hardware and software elements needed for the routine measurement of vital signs, performed by the patient or caregiver without having to go to a medical center.

Vital Signs – Defeating Breast Cancer

Centers for Disease Control (CDC) Podcasts

2012-11-12

This podcast is based on the November 2012 CDC Vital Signs report. Breast cancer is the second leading cause of cancer deaths among women in the United States. Better screening and treatment have contributed to a decline in breast cancer deaths, however, not all women have benefited equally from these improvements. Learn how we can all help reduce deaths from breast cancer.  Created: 11/12/2012 by Centers for Disease Control and Prevention (CDC).   Date Released: 11/12/2012.

CDC Vital Signs–HIV and Injection Drug Use

Centers for Disease Control (CDC) Podcasts

This podcast is based on the December 2016 CDC Vital Signs report. Sharing needles, syringes, and other injection equipment puts you at risk for getting HIV and other infections, including hepatitis. Learn how to reduce your HIV risk.

A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications.

Science.gov (United States)

Cook, R Kimberley; Deal, Megan E; Deal, Jennifer A; Garton, Russell D; Brown, C Adam; Ward, Megan E; Andrade, Rachel S; Spana, Eric P; Kaufman, Thomas C; Cook, Kevin R

2010-12-01

Interchromosomal duplications are especially important for the study of X-linked genes. Males inheriting a mutation in a vital X-linked gene cannot survive unless there is a wild-type copy of the gene duplicated elsewhere in the genome. Rescuing the lethality of an X-linked mutation with a duplication allows the mutation to be used experimentally in complementation tests and other genetic crosses and it maps the mutated gene to a defined chromosomal region. Duplications can also be used to screen for dosage-dependent enhancers and suppressors of mutant phenotypes as a way to identify genes involved in the same biological process. We describe an ongoing project in Drosophila melanogaster to generate comprehensive coverage and extensive breakpoint subdivision of the X chromosome with megabase-scale X segments borne on Y chromosomes. The in vivo method involves the creation of X inversions on attached-XY chromosomes by FLP-FRT site-specific recombination technology followed by irradiation to induce large internal X deletions. The resulting chromosomes consist of the X tip, a medial X segment placed near the tip by an inversion, and a full Y. A nested set of medial duplicated segments is derived from each inversion precursor. We have constructed a set of inversions on attached-XY chromosomes that enable us to isolate nested duplicated segments from all X regions. To date, our screens have provided a minimum of 78% X coverage with duplication breakpoints spaced a median of nine genes apart. These duplication chromosomes will be valuable resources for rescuing and mapping X-linked mutations and identifying dosage-dependent modifiers of mutant phenotypes.

CDC Vital Signs–Native Americans With Diabetes

Centers for Disease Control (CDC) Podcasts

This podcast is based on the January 2017 CDC Vital Signs report. Diabetes is the leading cause of kidney failure and Native Americans have a greater chance of having diabetes than any other racial group in the U.S. Learn how to manage your diabetes to delay or prevent kidney failure.

Assessing the Sociolinguistic Vitality of Istanbulite Romeyka: An Attitudinal Study

Science.gov (United States)

Schreiber, Laurentia; Sitaridou, Ioanna

2018-01-01

We assess the sociolinguistic vitality of Romeyka, the only Asia Minor Greek variety, which, albeit endangered, is still spoken in the Black Sea region, Turkey (historically known as Pontus), by means of nine extralinguistic (i.e. sociological) and sociolinguistic factors, specially tailored for the situation of Romeyka. Our current vitality…

Experiments and Research Programmes. Revisiting Vitalism/Non-Vitalism Debate in Early Twentieth Century

Directory of Open Access Journals (Sweden)

Bijoy MUKHERJEE

2012-06-01

Full Text Available Debates in the philosophy of science typically take place around issues such as realism and theory change. Recently, the debate has been reformulated to bring in the role of experiments in the context of theory change. As regards realism, Ian Hacking’s contribution has been to introduce ‘intervention’ as the basis of realism. He also proposed, following Imre Lakatos, to replace the issue of truth with progress and rationality. In this context we examine the case of the vitalism — reductionism debate in biology inspired by the works of Indian physicist-turned-biologist Jagadish Chandra Bose (1858–1937, in the early twentieth century. Both camps had their characteristic hardcores. Vitalists led by John S. Burdon-Sanderson and Augustus D. Waller accepted religious metaphysics to support their research programme, which ultimately degenerated. Bose worked more with the ideals of science such as Occam’s razor, large-scale systematization of phenomena and novel prediction. I argue that his religious metaphysics, instead of acting as a protective shield, helped him to consolidate his position and allowed further problem shift resulting in a research programme that involved consciousness too. His research programme remains relevant even today.

Vital Signs – When Food Bites Back

Centers for Disease Control (CDC) Podcasts

2013-06-04

This podcast is based on the June 2013 CDC Vital Signs report. It discusses food poisoning and specifically, Listeria. If you're 65 or older, have a weakened immune system, or are pregnant, you must be especially careful when selecting, preparing, and storing food.  Created: 6/4/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 6/4/2013.

Links between soil properties and steady-state solute transport through cultivated topsoil at the field scale

Science.gov (United States)

Koestel, J. K.; Norgaard, T.; Luong, N. M.; Vendelboe, A. L.; Moldrup, P.; Jarvis, N. J.; Lamandé, M.; Iversen, B. V.; Wollesen de Jonge, L.

2013-02-01

It is known that solute transport through soil is heterogeneous at all spatial scales. However, little data are available to allow quantification of these heterogeneities at the field scale or larger. In this study, we investigated the spatial patterns of soil properties, hydrologic state variables, and tracer breakthrough curves (BTCs) at the field scale for the inert solute transport under a steady-state irrigation rate which produced near-saturated conditions. Sixty-five undisturbed soil columns approximately 20 cm in height and diameter were sampled from the loamy topsoil of an agricultural field site in Silstrup (Denmark) at a sampling distance of approximately 15 m (with a few exceptions), covering an area of approximately 1 ha (60 m × 165 m). For 64 of the 65 investigated soil columns, we observed BTC shapes indicating a strong preferential transport. The strength of preferential transport was positively correlated with the bulk density and the degree of water saturation. The latter suggests that preferential macropore transport was the dominating transport process. Increased bulk densities were presumably related with a decrease in near-saturated hydraulic conductivities and as a consequence to larger water saturation and the activation of larger macropores. Our study provides further evidence that it should be possible to estimate solute transport properties from soil properties such as soil texture or bulk density. We also demonstrated that estimation approaches established for the column scale have to be upscaled when applied to the field scale or larger.

Quantitative Efficiency Evaluation Method for Transportation Networks

Directory of Open Access Journals (Sweden)

Jin Qin

2014-11-01

Full Text Available An effective evaluation of transportation network efficiency/performance is essential to the establishment of sustainable development in any transportation system. Based on a redefinition of transportation network efficiency, a quantitative efficiency evaluation method for transportation network is proposed, which could reflect the effects of network structure, traffic demands, travel choice, and travel costs on network efficiency. Furthermore, the efficiency-oriented importance measure for network components is presented, which can be used to help engineers identify the critical nodes and links in the network. The numerical examples show that, compared with existing efficiency evaluation methods, the network efficiency value calculated by the method proposed in this paper can portray the real operation situation of the transportation network as well as the effects of main factors on network efficiency. We also find that the network efficiency and the importance values of the network components both are functions of demands and network structure in the transportation network.

A pathway for hospital librarians: why is it vital?

Science.gov (United States)

Tooey, Mary Joan M J

2009-10-01

By the mid 2000s, reports of hospital librarians losing jobs and hospital libraries closing were rife. In 2005, Vital Pathways: The Hospital Libraries Project was established by 2005/06 MLA President M.J. Tooey, AHIP, FMLA, to assess the truth of these reports and to study and develop strategies to support hospital librarians. Throughout this long-term project, opportunities were sought to understand the issues more clearly. A steering committee, along with three task forces, was established to carry out the work of the project. The steering committee provided oversight and had responsibility for promoting and marketing the project. The three task forces were responsible for conducting a survey on the status of hospital librarians, determining the involvement of librarians in medical education and accreditation, and researching and writing a document reviewing current and future roles for hospital librarians. Along the way, these responsibilities grew and evolved. After a little more than three years, the Task Force on Vital Pathways for Hospital Librarians Steering Committee presented a final report regarding its accomplishments to the MLA Board of Directors. A sampling of these accomplishments includes the status of hospital librarians survey, a website, a position document with an accompanying executive summary, a short promotional brochure, and a final culminating activity, this symposium. Although these are difficult times for all libraries, hospital librarians and libraries seem particularly affected. In a competitive health care environment that is driven by the bottom line, influenced by real estate hunger, and affected by the belief of hospital administrators that access to health information comes from the Internet and is free, the hospital librarian seems doomed. However, even in these difficult times, there are hospital librarians who are not only surviving, but thriving. Is it because they are entrepreneurial? Opportunistic? Innovative? Flexible? All

Social dimensions and the impact of sustainable transport and mobility on social development.

CSIR Research Space (South Africa)

Chakwizira, J

2009-11-01

Full Text Available This chapter describes the relationship between transport, mobility and society. This is achieved by means of linking the social dimensions and impact of sustainable transport and mobility with approaches, principles and values of social development...

Urban Vitality in Dutch and Chinese New Towns. A comparative study between Almere and Tongzhou

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Jing Zhou

2017-11-01

correlation between space and the socio-economic life in new towns. As a market-driven, spontaneous new town, streets are the key places for socio-economic activities in Tongzhou. An essential spatial condition stimulating dynamic street life is found to be the open grid network structure with the mixture of diverse commercial, cultural and public programs widely dispersed on street frontages. The proliferation of groundfloor small businesses at the perimeters of neighborhoods in Tongzhou constitutes a big part of the street life, especially for the areas near public transport stations. As a top-down planned town, Almere excels at effective planning control and responsible social considerations, which benefits the long-term well-being of the city. Good urban governance is reflected not only in the public provisions and city marketing, but more importantly, in the quality of the public services and the available opportunities of citizen participation. For example, adaptable architectural design and bottom-up community planning implemented in Almere has positive impacts on animating local and perspective inhabitants, hence increasing urban vitality in another dimension. Interestingly, many of the home-based small businesses in Almere thrive by virtue of internet platform, despite that the effect is subtle in terms of bringing street activities. Both new towns need to further develop and experiment with new approaches of urban planning. Such new approaches are intended to be capable of creating a framework for a dynamic system to grow, balancing the planned and unplanned elements, involving a diversity of interested parties in the development process, being adaptive to changes over time, and emphasizing the quality of life for their citizens. Finally, the empirical and theoretical study findings are compared to each other. It results in a refined definition of urban vitality, which is synthesized into the placepeople-program triangle diagram, an enriched list of the favorable

Optimal traffic control in highway transportation networks using linear programming