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  1. Renal Denervation in a Real Life Setting: A Gradual Decrease in Home Blood Pressure.

    Directory of Open Access Journals (Sweden)

    Martine M A Beeftink

    Full Text Available To investigate the blood pressure dynamics after renal denervation through monthly home blood pressure measurements throughout the first 12 months.A cohort of 70 patients performed highly standardized monthly home blood pressure monitoring during the first year after denervation according to the European Society of Hypertension guidelines. At baseline and 12 months follow-up, office and ambulatory blood pressure as well as routine physical and laboratory assessment was performed.Home blood pressure decreased with a rate of 0.53 mmHg/month (95% CI 0.20 to 0.86 systolic and 0.26 mmHg/month (95% CI 0.08 to 0.44 diastolic throughout 12 months of follow-up, while the use of antihypertensive medication remained stable (+0.03 daily defined doses/month, 95% CI -0.01 to 0.08. On average, a 12 month reduction of 8.1 mmHg (95% CI 4.2 to 12.0 was achieved in home systolic blood pressure, 9.3 mmHg (95% CI -14.2 to -4.4 as measured by 24-hour ambulatory blood pressure monitoring and 15.9 mmHg (95% CI -23.8 to -7.9 on office measurements.Blood pressure reduction after renal denervation occurs as a gradual decrease that extends to at least one-year follow-up. Home monitoring seems a suitable alternative for ambulatory blood pressure monitoring after renal denervation.

  2. Preschool Children’s Memory for Word Forms Remains Stable Over Several Days, but Gradually Decreases after Six Months

    Directory of Open Access Journals (Sweden)

    Katherine Ruth Gordon

    2016-09-01

    Full Text Available Research on word learning has focused on children’s ability to identify a target object when given the word form after a minimal number of exposures to novel word-object pairings. However, relatively little research has focused on children’s ability to retrieve the word form when given the target object. The exceptions involve asking children to recall and produce forms, and children typically perform near floor on these measures. In the current study, 3- to 5-year-old children were administered a novel test of word form that allowed for recognition memory and manual responses. Specifically, when asked to label a previously trained object, children were given three forms to choose from: the target, a minimally different form, and a maximally different form. Children demonstrated memory for word forms at three post-training delays: 10 minutes (short-term, 2 to 3 days (long-term, and 6 months to 1 year (very long-term. However, children performed worse at the very long-term delay than the other time points, and the length of the very long-term delay was negatively related to performance. When in error, children were no more likely to select the minimally different form than the maximally different form at all time points. Overall, these results suggest that children remember word forms that are linked to objects over extended post-training intervals, but that their memory for the forms gradually decreases over time without further exposures. Furthermore, memory traces for word forms do not become less phonologically specific over time; rather children either identify the correct form, or they perform at chance.

  3. Gradual collective wage bargaining

    NARCIS (Netherlands)

    Dobbelaere, S.; Luttens, R.I.

    2016-01-01

    This paper presents an alternative implementation of firm-level collective wage bargaining, where bargaining proceeds as a finite sequence of sessions between a firm and a union of variable size. We investigate the impact of such a 'gradual' union on the wage-employment contract in an economy with

  4. Empirical tests of the Gradual Learning Algorithm

    NARCIS (Netherlands)

    Boersma, P.; Hayes, B.

    1999-01-01

    The Gradual Learning Algorithm (Boersma 1997) is a constraint ranking algorithm for learning Optimality-theoretic grammars. The purpose of this article is to assess the capabilities of the Gradual Learning Algorithm, particularly in comparison with the Constraint Demotion algorithm of Tesar and

  5. Empirical tests of the Gradual Learning Algorithm

    NARCIS (Netherlands)

    Boersma, P.; Hayes, B.

    2001-01-01

    The Gradual Learning Algorithm (Boersma 1997) is a constraint-ranking algorithm for learning optimality-theoretic grammars. The purpose of this article is to assess the capabilities of the Gradual Learning Algorithm, particularly in comparison with the Constraint Demotion algorithm of Tesar and

  6. Gradual Rewarming with Gradual Increase in Pressure during Machine Perfusion after Cold Static Preservation Reduces Kidney Ischemia Reperfusion Injury.

    Directory of Open Access Journals (Sweden)

    Paria Mahboub

    Full Text Available In this study we evaluated whether gradual rewarming after the period of cold ischemia would improve organ quality in an Isolated Perfused Kidney Model. Left rat kidneys were statically cold stored in University of Wisconsin solution for 24 hours at 4°C. After cold storage kidneys were rewarmed in one of three ways: perfusion at body temperature (38°C, or rewarmed gradually from 10°C to 38°C with stabilization at 10°C for 30 min and rewarmed gradually from 10°C to 38°C with stabilization at 25°C for 30 min. In the gradual rewarming groups the pressure was increased stepwise to 40 mmHg at 10°C and 70 mmHg at 25°C to counteract for vasodilatation leading to low perfusate flows. Renal function parameters and injury biomarkers were measured in perfusate and urine samples. Increases in injury biomarkers such as aspartate transaminase and lactate dehydrogenase in the perfusate were lower in the gradual rewarming groups versus the control group. Sodium re-absorption was improved in the gradual rewarming groups and reached significance in the 25°C group after ninety minutes of perfusion. HSP-70, ICAM-1, VCAM-1 mRNA expressions were decreased in the 10°C and 25°C groups. Based on the data kidneys that underwent gradual rewarming suffered less renal parenchymal, tubular injury and showed better endothelial preservation. Renal function improved in the gradual rewarming groups versus the control group.

  7. RETRACTED ARTICLE: Gradually varied flow computation in ...

    Indian Academy of Sciences (India)

    Mohammad Jahandar Malekabadi

    The article ''Gradually varied flow computation in channel networks by adaptive algorithm'' (DOI 10.1007/s12046- · 017-0640-x) which has been published online has been retracted by Chief Editor of the journal Sadhana as per the. Committee on Publication Ethics (COPE) guidelines on redundant publication.

  8. Ratio-Based Gradual Aggregation of Data

    DEFF Research Database (Denmark)

    Iftikhar, Nadeem

    2012-01-01

    cause data management and data storage issues. However, non-flexible and ineffective means of data aggregation not only reduce performance of database queries but also lead to erroneous reporting. This paper presents flexible and effective ratio-based methods for gradual data aggregation in databases....... Gradual data aggregation is a process that reduces data volume by converting the detailed data into multiple levels of summarized data as the data gets older. This paper also describes implementation strategies of the proposed methods based on standard database technology.......Majority of databases contain large amounts of data, gathered over long intervals of time. In most cases, the data is aggregated so that it can be used for analysis and reporting purposes. The other reason of data aggregation is to reduce data volume in order to avoid over-sized databases that may...

  9. Gradual Ordering in Red Abalone Nacre

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, P. U. P. A.; Metzler, Rebecca A.; Zhou, Dong; Scholl, Andreas; Doran, Andrew; Young, Anthony; Kunz, Martin; Tamura, Nobumichi; Coppersmith, Susan N.

    2008-09-03

    Red abalone (Haliotis rufescens) nacre is a layered composite biomineral that contains crystalline aragonite tablets confined by organic layers. Nacre is intensely studied because its biologically controlled microarchitecture gives rise to remarkable strength and toughness, but the mechanisms leading to its formation are not well understood. Here we present synchrotron spectromicroscopy experiments revealing that stacks of aragonite tablet crystals in nacre are misoriented with respect to each other. Quantitative measurements of crystal orientation, tablet size, and tablet stacking direction show that orientational ordering occurs not abruptly but gradually over a distance of 50 {micro}m. Several lines of evidence indicate that different crystal orientations imply different tablet growth rates during nacre formation. A theoretical model based on kinetic and gradual selection of the fastest growth rates produces results in qualitative and quantitative agreement with the experimental data and therefore demonstrates that ordering in nacre is a result of crystal growth kinetics and competition either in addition or to the exclusion of templation by acidic proteins as previously assumed. As in other natural evolving kinetic systems, selection of the fastest-growing stacks of tablets occurs gradually in space and time. These results suggest that the self-ordering of the mineral phase, which may occur completely independently of biological or organic-molecule control, is fundamental in nacre formation.

  10. Large gradual solar energetic particle events

    Directory of Open Access Journals (Sweden)

    Mihir Desai

    2016-09-01

    Full Text Available Abstract Solar energetic particles, or SEPs, from suprathermal (few keV up to relativistic ( $$\\sim $$ ∼ few GeV energies are accelerated near the Sun in at least two ways: (1 by magnetic reconnection-driven processes during solar flares resulting in impulsive SEPs, and (2 at fast coronal-mass-ejection-driven shock waves that produce large gradual SEP events. Large gradual SEP events are of particular interest because the accompanying high-energy ( $${>}10$$ > 10 s MeV protons pose serious radiation threats to human explorers living and working beyond low-Earth orbit and to technological assets such as communications and scientific satellites in space. However, a complete understanding of these large SEP events has eluded us primarily because their properties, as observed in Earth orbit, are smeared due to mixing and contributions from many important physical effects. This paper provides a comprehensive review of the current state of knowledge of these important phenomena, and summarizes some of the key questions that will be addressed by two upcoming missions—NASA’s Solar Probe Plus and ESA’s Solar Orbiter. Both of these missions are designed to directly and repeatedly sample the near-Sun environments where interplanetary scattering and transport effects are significantly reduced, allowing us to discriminate between different acceleration sites and mechanisms and to isolate the contributions of numerous physical processes occurring during large SEP events.

  11. Selection of phytoplankton species in culture by gradual salinity changes

    Science.gov (United States)

    Rijstenbil, J. W.

    Continuous cultures of mixed phytoplankton populations were subjected to gradual salinity changes. The phytoplankton was exposed to defined regimes of high, low or fluctuating salinity, in artificial brackish media. In several experiments ammonium was the limiting nutrient. A rapid selection process was observed in natural phytoplankton assemblages. A gradual freshening caused the dominance of Chaetoceros mülleri at low salinity (S = 5). Skeletonema costatum became dominant at higher, constant or fluctuating salinities, accompanied by Ditylum brightwellii in low cell numbers. Ammonium limitation was not achieved in this experiment. Competition for ammonium was studied in a second experiment, using an inoculum of two species. At S = 18 D. brighwellii became the dominant species in this competition. A minor shift towards S = 15 reversed the affinities for ammonium, and S. costatum won the competition. At S = 8 S. costatum had the highest affinity for ammonium after a period of osmotic adjustment. Ammonium became limiting when salinities arrived at constant meso- or polyhaline levels. Both species were able to grow in fluctuating osmotic environments (S = 5 to 19). The growth of D. brightwellii decreased below S = 8 and after repeated variations of the salinity. These salinity fluctuations suppressed growth and ammonium uptake of both species, thus preventing ammonium limitation. These competition experiments indicate that unstable salinity may stimulate the mass development of S. costatum in brackish lakes.

  12. Are Vicinal Metal Surfaces Stable?

    DEFF Research Database (Denmark)

    Frenken, J. W. M.; Stoltze, Per

    1999-01-01

    We use effective medium theory to demonstrate that the energies of many metal surfaces are lowered when these surfaces are replaced by facets with lower-index orientations. This implies that the low-temperature equilibrium shapes of many metal crystals should be heavily faceted. The predicted ins...... instability of vicinal metal surfaces is at variance with the almost generally observed stability of these surfaces. We argue that the unstable orientations undergo a defaceting transition at relatively low temperatures, driven by the high vibrational entropy of steps....

  13. Renal denervation in a real life setting : A gradual decrease in home blood pressure

    NARCIS (Netherlands)

    Beeftink, Martine M A; Spiering, Wilko|info:eu-repo/dai/nl/269114173; Bots, Michiel L.|info:eu-repo/dai/nl/110610032; Verloop, Willemien L.; De Jager, Rosa L.; Sanders, Margreet F.; Vonken, Evert Jan|info:eu-repo/dai/nl/188058796; Blankestijn, Peter J.|info:eu-repo/dai/nl/086704850; Voskuil, Michiel|info:eu-repo/dai/nl/254745954

    2016-01-01

    OBJECTIVES: To investigate the blood pressure dynamics after renal denervation through monthly home blood pressure measurements throughout the first 12 months. METHODS: A cohort of 70 patients performed highly standardized monthly home blood pressure monitoring during the first year after

  14. Effect of the Antibiotic Neomycin on the Toxicity of the Glycoside Vicine in Rats

    National Research Council Canada - National Science Library

    Arbid, Mahmoud S; Koriem, Khaled M. M; Asaad, Gihan F; Megahed, Hoda A

    2013-01-01

    .... Hemoglobin (Hb) concentration, hematocrit (Hct) value, and red blood cells (RBCs) count were significantly decreased after injection of vicine and the improvement of these values in the group pretreated with neomycin...

  15. Gradual Reliability Sensitivity Analysis of Mechanical Part Considering Preventive Maintenance

    OpenAIRE

    Li Changyou; Liu Haiyang; Guo Song; Zhang Yimin; Li Zhenyuan

    2014-01-01

    A lot of mechanical parts are subject to failure due to the deterioration. Usually the preventive maintenance is taken to ensure the safety and reliability. Therefore, it is very important to study the gradual reliability design of the mechanical part for improving the gradual reliability of the mechanical system under the condition of considering the preventive maintenance. Beta distribution is employed to describe the randomness of the mechanical part state after the preventive maintenance....

  16. Adaptation of the white shrimp Litopenaeus vannamei to gradual changes to a low-pH environment.

    Science.gov (United States)

    Han, Si-Yin; Wang, Bao-Jie; Liu, Mei; Wang, Meng-Qiang; Jiang, Ke-Yong; Liu, Xin-Wei; Wang, Lei

    2018-03-01

    pH variation could cause a stress response in euryhaline penaeids, we evaluated the mortality, growth performance, osmoregulation gene expression, digestive enzyme activity, histology, and resistance against Vibrio parahemolyticus of white shrimp Litopenaeus vannamei reared under conditions of gradual changes to a low-pH environment (gradual-low pH, 6.65-8.20) or a high-pH environment (gradual-high pH, 8.20-9.81) versus a normal pH environment (8.14-8.31) during a 28-d experiment. Consequently, under gradual-high pH, the cumulative mortality rate (CMR) rose with time until 39.9% on days 28; the weight gain percentage (WGP) and length gain percentage (LGP) decreased continuously. However, under gradual-low pH, the CMR of shrimp stabilized at 6.67% during 7-28 d; the WGP and LGP decreased first and then returned to normal. These results indicated that L. vannamei displayed a moderate tolerance to gradual-low pH, compared with gradual-high pH. Under gradual-low pH, the Na+/K+-ATPase, cytoplasmic carbonic anydrase (CAc), and glycosyl-phosphatidylinositol-linked carbonic anhydrase (CAg) transcripts of shrimp increased continuously or then back to normal; the amylase, lipase, and trypsin activities decreased first and then returned to normal or increased; the hepatopancreases and midguts showed histopathological lesions first and then got remission. Thus, the major adaptation mechanism of shrimp to gradual-low pH might be its high osmoregulation ability, which made shrimp achieve a new, balanced steady-state, then promoted longer intestinal villi and recuperative hepatopancreases of shrimp with enhanced digestive enzyme activities to increase nutrient absorption after long-term exposure. Meanwhile, the enhanced resistance against V. parahemolyticus under gradual-low pH would probably inhibit disease outbreak in the shrimp farming. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. A born global’s radical, gradual and nonlinear internationalization

    DEFF Research Database (Denmark)

    Vissak, Tiia; Zhang, Xiaotian

    2016-01-01

    a case of a Belarusian door producer that has invested to seven and exported to 11 more countries, we conclude that a home country’s political, economic environment can be a crucial ‘push’ factor for a firm’s fast internationalization but, thereafter, it can internationalize gradually due to lacking......This paper contributes to the literature on internationalization processes by showing that a born global can experience nonlinear internationalization (de-and re-internationalize) after radical, fast initial growth, and use some subsidiaries as bases for further gradual expansion. After studying...

  18. Habitat--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the habitat map of the seafloor of the Monterey Canyon and Vicinity map area, California. The vector data file is included in...

  19. Contours--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents bathymetric contours for several seafloor maps of the Monterey Canyon and Vicinity map area, California. The raster data file is...

  20. Computation of gradually varied flow in compound open channel ...

    Indian Academy of Sciences (India)

    In this method, the energy and continuity equations are solved for steady, gradually varied flow by the Newton–Raphson method and the proposed methodology is applied to tree-type and looped-channel networks. An algorithm is presented to determine multiple critical depths in a compound channel. Modifications in ...

  1. Abrupt or gradual increases in photoperiod for broiler breeders ...

    African Journals Online (AJOL)

    Broiler breeders transferred from closed rearing to curtain-sided adult accommodation (similar to that in which a large proportion of broiler breeders are housed) respond similarly to abrupt and gradual increases in daylength as do birds maintained throughout in controlled environment accommodation, and modern ...

  2. Diurnal gradual heat stress affects antioxidant enzymes, proline ...

    African Journals Online (AJOL)

    Even though high temperatures significantly reduce both vegetative growth and yield in cotton, very little is known about the effects of heat stress on cotton antioxidant system. Thus, the effects of gradual heat stress on cotton growth in controlled conditions were investigated in the present study. At squaring stage, cotton ...

  3. Is synaesthesia really stable – or does it gradually consolidate?

    DEFF Research Database (Denmark)

    Sørensen, Thomas Alrik

    is that the associations are stable over time. However, here we present the case of AR, a colour-grapheme synaesthete who clearly demonstrate synaesthesia, but also a gradual consolidation over time (Sørensen, Nordfang, & Ásgeirsson, accepted). Also, AR does not demonstrate some of the typical modulations of attention...

  4. Mathematical Modelling of the Gradual Aging of Systems using the ...

    African Journals Online (AJOL)

    Mathematical Modelling of the Gradual Aging of Systems using the weibull hazard function. ... Journal of the Nigerian Association of Mathematical Physics ... This paper proposes a mathematical model for obtaining the shape and scale parameters, and the implication of these parameters in obtaining the aging coefficient of ...

  5. Gradual Rewarming with Gradual Increase in Pressure during Machine Perfusion after Cold Static Preservation Reduces Kidney Ischemia Reperfusion Injury

    NARCIS (Netherlands)

    Mahboub, Paria; Ottens, Petra; Seelen, Marc; 't Hart, Nails; van Goor, Harry; Ploeg, Rutger; Martins, Paulo; Leuvenink, Henri

    2015-01-01

    In this study we evaluated whether gradual rewarming after the period of cold ischemia would improve organ quality in an Isolated Perfused Kidney Model. Left rat kidneys were statically cold stored in University of Wisconsin solution for 24 hours at 4 degrees C. After cold storage kidneys were

  6. Sudden Death and Gradual Decay in Visual Working Memory

    OpenAIRE

    Zhang, Weiwei; Luck, Steven J.

    2009-01-01

    General Douglas MacArthur famously remarked that “Old soldiers never die; they just fade away” (General Douglas MacArthur, April 19, 1951). For decades, researchers have concluded that visual working memories, like old soldiers, fade away gradually, becoming progressively less precise as they are retained for longer periods of time. However, these conclusions were based on threshold estimation procedures in which the complete termination of a memory could artifactually produce the appearance ...

  7. Impairment of gradual muscle adjustment during wrist circumduction in Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Carolien M Toxopeus

    Full Text Available Purposeful movements are attained by gradually adjusted activity of opposite muscles, or synergists. This requires a motor system that adequately modulates initiation and inhibition of movement and selectively activates the appropriate muscles. In patients with Parkinson's disease (PD initiation and inhibition of movements are impaired which may manifest itself in e.g. difficulty to start and stop walking. At single-joint level, impaired movement initiation is further accompanied by insufficient inhibition of antagonist muscle activity. As the motor symptoms in PD primarily result from cerebral dysfunction, quantitative investigation of gradually adjusted muscle activity during execution of purposeful movement is a first step to gain more insight in the link between impaired modulation of initiation and inhibition at the levels of (i cerebrally coded task performance and (ii final execution by the musculoskeletal system. To that end, the present study investigated changes in gradual adjustment of muscle synergists using a manipulandum that enabled standardized smooth movement by continuous wrist circumduction. Differences between PD patients (N = 15, off-medication and healthy subjects (N = 16 concerning the relation between muscle activity and movement performance in these groups were assessed using kinematic and electromyographic (EMG recordings. The variability in the extent to which a particular muscle was active during wrist circumduction--defined as muscle activity differentiation--was quantified by EMG. We demonstrated that more differentiated muscle activity indeed correlated positively with improved movement performance, i.e. higher movement speed and increased smoothness of movement. Additionally, patients employed a less differentiated muscle activity pattern than healthy subjects. These specific changes during wrist circumduction imply that patients have a decreased ability to gradually adjust muscles causing a decline in

  8. Using a Time Granularity Table for Gradual Granular Data Aggregation

    DEFF Research Database (Denmark)

    Iftikhar, Nadeem; Pedersen, Torben Bach

    2010-01-01

    The majority of today’s systems increasingly require sophisticated data management as they need to store and to query large amounts of data for analysis and reporting purposes. In order to keep more “detailed” data available for longer periods, “old” data has to be reduced gradually to save space...... is 6 months old aggregate to 2 minutes level from 1 minute level and so on. The proposed solution introduces a time granularity based data structure, namely a relational time granularity table that enables long term storage of old data by maintaining it at different levels of granularity and effective...

  9. Molecular sieving action of the cell membrane during gradual osmotic hemolysis

    Energy Technology Data Exchange (ETDEWEB)

    MacGregor, R.D. II

    1977-05-01

    Rat erythrocytes were hemolyzed by controlled gradual osmotic hemolysis to study cell morphology and hemoglobin loss from individual cells. Results suggest that each increase in the rate of loss of a protein from the cells during the initial phases of controlled gradual osmotic hemolysis is caused by the passage of a previously impermeable species across the stressed membrane. Similarly, during the final stages of controlled gradual osmotic hemolysis, each sharp decrease in the rate of loss of a protein corresponds to the termination of a molecular flow. A theoretical model is described that predicts the molecular sieving of soluble globular proteins across the stressed red cell membrane. Hydrophobic interactions occur between the soluble proteins and the lipid bilayer portion of the cell membrane. A spectrin network subdivides the bilayer into domains that restrict the insertion of large molecules into the membrane. Other membrane proteins affect soluble protein access to the membrane. Changes in the loss curves caused by incubation of red cells are discussed in terms of the model.

  10. GRADUAL TRANSITION DETECTION FOR VIDEO PARTITIONING USING MORPHOLOGICAL OPERATORS

    Directory of Open Access Journals (Sweden)

    Valery Naranjo

    2011-05-01

    Full Text Available Temporal segmentation of video data for partitioning the sequence into shots is a prerequisite in many applications: automatic video indexing and editing, old flm restoration, perceptual coding, etc. The detection of abrupt transitions or cuts has been thoroughly studied in previous works. In this paper we present a scheme to identify the most common gradual transitions, i.e., dissolves and wipes, which relies on mathematical morphology operators. The approach is restricted to fast techniques which require low computation (without motion estimation and adapted to compressed sequences and are able to cope with random brightness variations (often occurring in old flms. The present study illustrates how the morphological operators can be used to analyze temporal series for detecting particular events, either working directly on the 1D signal or building an intermediate 2D image from the 1D signals to take advantage of the spatial operators.

  11. Sudden death and gradual decay in visual working memory.

    Science.gov (United States)

    Zhang, Weiwei; Luck, Steven J

    2009-04-01

    General Douglas MacArthur remarked that "old soldiers never die; they just fade away." For decades, researchers have concluded that visual working memories, like old soldiers, fade away gradually, becoming progressively less precise as they are retained for longer periods of time. However, these conclusions were based on threshold-estimation procedures in which the complete termination of a memory could artifactually produce the appearance of lower precision. Here, we use a recall-based visual working memory paradigm that provides separate measures of the probability that a memory is available and the precision of the memory when it is available. Using this paradigm, we demonstrate that visual working memory representations may be retained for several seconds with little or no loss of precision, but that they may terminate suddenly and completely during this period.

  12. Impact of Brick Kilns’ Emission on Soil Quality of Agriculture Fields in the Vicinity of Selected Bhaktapur Area of Nepal

    Directory of Open Access Journals (Sweden)

    Gunjan Bisht

    2015-01-01

    Full Text Available The study was conducted to evaluate soil quality and impact of brick kiln on different physicochemical parameters of soils of agricultural field, located in the vicinity of Bhaktapur, Nepal. The study was carried out by determining the physicochemical characteristics of soil, soil fertility, and heavy metal contamination of soil. During the entire study period, water absorptivity of soil ranged from 2.4 to 3.3 mg/L, pH varies from 5.885 to 7.64, and organic carbon content and organic matter varied from 0.277 to 0.93%, from 0.477% to 1.603%, respectively. Nutrient content, that is, sulfate and nitrate concentration, in the soil ranged from 0.829 to 3.764 mol/L and from 0.984 to 29.99 mol/L, respectively. The findings revealed that concentrations of heavy metals (chromium and lead were within permissible limit, although the levels were higher in soil at 50 m and decrease farther from brick kiln. However, the physical parameters and nutrient content were deficient in soil at 50 m while increasing gradually at distances of 100 m and 150 m. The variation of result obtained for physical parameters supports the fact that quality of soil in terms of heavy metal content and nutrient content was directly proportional to the distance from the kiln; that is, the quality of soil increased with increasing distance.

  13. Intergranular Corrosion of Σ9 Copper Bicrystal with Gradually Changed Misorientation in Young's Dislocation Etchant

    Science.gov (United States)

    Takehara, Yuhei; Fujiwara, Hiroshi; Miyamoto, Hiroyuki

    2013-08-01

    The allowable deviation to preserve the "specialness" of a coincident site lattice (CSL) boundary was shown using a pure copper bicrystal which was designed to have gradually changed deviation around axis from near-ideal Σ9{221} to a random relation. The grain boundary preserved immunity to grain boundary corrosion in Young's dislocation etchant until the deviation reached the angle where the misfit dislocation spacing is supposed to decrease to CSL dimension. This underlies the common principle of the Brandon-type criteria of CSL.

  14. From manual gesture to speech: a gradual transition.

    Science.gov (United States)

    Gentilucci, Maurizio; Corballis, Michael C

    2006-01-01

    There are a number of reasons to suppose that language evolved from manual gestures. We review evidence that the transition from primarily manual to primarily vocal language was a gradual process, and is best understood if it is supposed that speech itself a gestural system rather than an acoustic system, an idea captured by the motor theory of speech perception and articulatory phonology. Studies of primate premotor cortex, and, in particular, of the so-called "mirror system" suggest a double hand/mouth command system that may have evolved initially in the context of ingestion, and later formed a platform for combined manual and vocal communication. In humans, speech is typically accompanied by manual gesture, speech production itself is influenced by executing or observing hand movements, and manual actions also play an important role in the development of speech, from the babbling stage onwards. The final stage at which speech became relatively autonomous may have occurred late in hominid evolution, perhaps with a mutation of the FOXP2 gene around 100,000 years ago.

  15. The Gradual Transformation of the Polish Public Science System

    Science.gov (United States)

    Heinecke, Steffi

    2016-01-01

    This paper investigates institutional change in the Polish public science system (PPSS) in the past twenty years. Employing macro-statistical data, the paper argues that this change process has unfolded stepwise and relatively late despite major political and economic transformations in post-socialist Poland. Using a historical-institutionalist perspective, the paper focuses on processes of institutional change, including layering, displacement, and dismantling. One major finding is that the speed and depth of the gradual transformation differs considerably between the three research performing sectors of the Polish public science system. As the Polish Academy of Sciences was reproduced institutionally, the former governmental units for applied R&D were partly dismantled and displaced by private sector R&D units. In contrast, the Higher Education sector underwent a strong expansion and, thus, layering of new research activities and fields. Since policy shifts within the PPSS occurred relatively late, the more than two decades following the collapse of communism are of special interest to scholars of incremental, yet cumulative, institutional change. PMID:27077386

  16. Gradual reintroduction of oxygen reduces reperfusion injury in cat stomach

    Energy Technology Data Exchange (ETDEWEB)

    Perry, M.A.; Wadhwa, S.S. (Univ. of New South Wales, Sydney (Australia))

    1988-03-01

    Recent studies have shown that oxygen-derived free radicals are responsible for a major portion of ischemia-reperfusion injury in the stomach. The oxygen radicals are produced during perfusion when oxygen delivery to the tissue increases. In the present study the authors investigate the effect on mucosal injury of regulating the rate of reintroduction of oxygen to the stomach after ischemia. Local gastric ischemia was achieved by reducing celiac artery pressure to 30 mmHg for 1 h. Ischemic injury was assessed by measuring the loss of {sup 51}Cr-labeled red blood cells across the gastric mucosa. Mucosal blood loss was negligible before and during the ischemia period but increased during reperfusion. When blood flow to the stomach was gradually returned to normal after ischemia, the mucosal blood loss was reduced. If the stomach was vascularly perfused with low Po{sub 2} blood for 1 h after ischemia before being returned to normal arterial perfusion, the mucosal blood loss was also reduced. When the stomach was made hypoxemic for 1 h rather than ischemic by perfusing the vasculature with low Po{sub 2} blood then reperfused with normoxic blood, there was very little mucosal bleeding. The data indicate that gastric mucosal bleeding after ischemia is reduced if the tissue is returned slowly to a normal Po{sub 2}. These findings support the concept that reperfusion injury is due largely to the production of oxygen radicals. The low level of injury produced by hypoxemia indicates that hypoxia per se makes only a minor contribution to reperfusion injury in the stomach.

  17. Demographic analysis reveals gradual senescence in the flatworm Macrostomum lignano

    Directory of Open Access Journals (Sweden)

    Braeckman Bart P

    2009-07-01

    Full Text Available Abstract Free-living flatworms ("Turbellaria" are appropriate model organisms to gain better insight into the role of stem cells in ageing and rejuvenation. Ageing research in flatworms is, however, still scarce. This is partly due to culture difficulties and the lack of a complete set of demographic data, including parameters such as median lifespan and age-specific mortality rate. In this paper, we report on the first flatworm survival analysis. We used the species Macrostomum lignano, which is an emerging model for studying the reciprocal influence between stem cells, ageing and rejuvenation. This species has a median lifespan of 205 ± 13 days (average ± standard deviation [SD] and a 90th percentile lifespan of 373 ± 32 days. The maximum lifespan, however, is more than 745 days, and the average survival curve is characterised by a long tail because a small number of individuals lives twice as long as 90% of the population. Similar to earlier observations in a wide range of animals, in M. lignano the age-specific mortality rate increases exponentially, but levels off at the oldest ages. To compare the senescence of M. lignano with that of other ageing models, we determined the mortality rate doubling time, which is 0.20 ± 0.02 years. As a result, we can conclude that M. lignano shows gradual senescence at a rate similar to the vertebrate ageing models Rattus norvegicus and Mus musculus. We argue that M. lignano is a suitable model for ageing and rejuvenation research, and especially for the role of stem cells in these processes, due to its accessible stem cell system and regeneration capacity, and the possibility of combining stem cell studies with demographic analyses.

  18. Demographic analysis reveals gradual senescence in the flatworm Macrostomum lignano.

    Science.gov (United States)

    Mouton, Stijn; Willems, Maxime; Back, Patricia; Braeckman, Bart P; Borgonie, Gaetan

    2009-07-30

    Free-living flatworms ("Turbellaria") are appropriate model organisms to gain better insight into the role of stem cells in ageing and rejuvenation. Ageing research in flatworms is, however, still scarce. This is partly due to culture difficulties and the lack of a complete set of demographic data, including parameters such as median lifespan and age-specific mortality rate. In this paper, we report on the first flatworm survival analysis. We used the species Macrostomum lignano, which is an emerging model for studying the reciprocal influence between stem cells, ageing and rejuvenation. This species has a median lifespan of 205 +/- 13 days (average +/- standard deviation [SD]) and a 90th percentile lifespan of 373 +/- 32 days. The maximum lifespan, however, is more than 745 days, and the average survival curve is characterised by a long tail because a small number of individuals lives twice as long as 90% of the population. Similar to earlier observations in a wide range of animals, in M. lignano the age-specific mortality rate increases exponentially, but levels off at the oldest ages. To compare the senescence of M. lignano with that of other ageing models, we determined the mortality rate doubling time, which is 0.20 +/- 0.02 years. As a result, we can conclude that M. lignano shows gradual senescence at a rate similar to the vertebrate ageing models Rattus norvegicus and Mus musculus. We argue that M. lignano is a suitable model for ageing and rejuvenation research, and especially for the role of stem cells in these processes, due to its accessible stem cell system and regeneration capacity, and the possibility of combining stem cell studies with demographic analyses.

  19. Decreased Libido

    Science.gov (United States)

    ... such as those taken for prostate cancer) Excessive alcohol use or recreational drug use Excessive fatigue Systemic illness (such as chronic lung, heart, kidney and liver failure, cancer) Low testosterone (male hypogonadism) Depression Relationship problems What is the treatment for decreased libido? ...

  20. Self-assembled nanostructures on vicinal surfaces

    Science.gov (United States)

    Petrovykh, Dmitri Yourievich

    2000-10-01

    One of the first methods for visualizing crystal planes and atomic steps has been step decoration with gold on alkali-halide surfaces. An impressive body of work has been conducted since then on the role of steps in controlling surface diffusion and adsorption rates, catalytic and chemical activity, and other physical and chemical surface properties. Due to these special characteristics, vicinal surfaces offer an approach for creating self-assembled structures with one or more dimensions on nanometer scale. The storage and communications industries have been revolutionized by applications of two-dimensional electron gas confined in thin films, so an interest in one and zero-dimensional systems is not surprising. This work demonstrates how macroscopic amounts of low-dimensional structures can be produced by self-assembly using stepped surfaces as nanometer-scale templates. High-quality templates of step arrays can be prepared on vicinal Si(111) surfaces. Sub-monolayer CaF2/Si(111) heteroepitaxial growth is examined in a series of experiments. A new growth mode is observed in addition to the ones typical in three dimensions. With increasing coverage, the growth front changes from rough to smooth geometry, driven by the elastic interactions between the multiple growth fronts and the surface steps. The mechanism is thus unique to the two-dimensional growth on stepped surfaces. The possible arrangements of the CaF2 self-assembled nanostructures are arrays of stripes or islands, both interesting as potential masks for silicon nanolithography. Anisotropic surface reconstructions, such as Ca and Au induced 3 x 1 and 5 x 2 on Si(111), are effectively self-assembled one-dimensional atomic chains. Reconstructions are single-domain on vicinal surfaces and with odd electron count a metallic one-dimensional state is expected in both the above examples. However in angular-resolved photoemission both appear as semiconductors, and Au-Si(111)5 x 2 exhibits a continuous one

  1. Optimization of gradual hemolysis for isolation of hemoglobin from bovine erythrocytes

    Directory of Open Access Journals (Sweden)

    Pravilović Radoslava

    2012-01-01

    Full Text Available In this work, we describe an optimized procedure based on gradual hemolysis for the isolation of hemoglobin derived from bovine slaughterhouse erythrocytes in a membrane bioreactor. The membrane bioreactor system provided high yields of hemoglobin (mainly oxyhemoglobin derivate and its separation from the empty erythrocyte membranes (ghosts. Ten different concentrations of hypotonic media were assessed from the aspect of the extent of hemolysis, hematocrit values of the erythrocyte suspensions, cell swelling and membrane deformations induced by decreased salt concentration. Effective gradual osmotic hemolysis with an extent of hemolysis of 83% was performed using 35 mM Na-phosphate/NaCl buffer of pH 7.2-7.4. Under these conditions most of the cell membranes presented the appearance of the normal ghosts under phase contrast microscope. The results show that isolation process yielded predominantly to oxyhemoglobin. Kinetic studies showed that maximal concentration of hemoglobin was reached after 40 min, but the process cycle at which recovery of 83% was achieved lasted for 90 min.

  2. Gradual Changes of Gut Microbiota in Weaned Miniature Piglets

    Directory of Open Access Journals (Sweden)

    Xianghua Yan

    2016-11-01

    Full Text Available Colonization of gut microbiota in mammals during the early life is vital to host health. The miniature piglet has recently been considered as an optimal infant model. However, less is known about the development of gut microbiota in miniature piglets. Here, this study was conducted to explore how the gut microbiota develops in weaned Congjiang miniature piglets. In contrast to the relatively stabilized gut fungal community, gut bacterial community showed a marked drop in alpha diversity, accompanied by significant alterations in taxonomic compositions. The relative abundances of 24 bacterial genera significantly declined, whereas the relative abundances of 7 bacterial genera (Fibrobacter, Collinsella, Roseburia, Prevotella, Dorea, Howardella, and Blautia significantly increased with the age of weaned piglets. Fungal taxonomic analysis showed that the relative abundances of 2 genera (Kazachstania and Aureobasidium significantly decreased, whereas the relative abundances of 4 genera (Aspergillus, Cladosporium, Simplicillium, and Candida significantly increased as the piglets aged. Kazachstania telluris was the signature species predominated in gut fungal communities of weaned miniature piglets. The functional maturation of the gut bacterial community was characterized by the significantly increased digestive system, glycan biosynthesis and metabolism, and vitamin B biosynthesis as the piglets aged. These findings suggest that marked gut microbial changes in Congjiang miniature piglets may contribute to understand the potential gut microbiota development of weaned infants.

  3. Gradual Changes of Gut Microbiota in Weaned Miniature Piglets.

    Science.gov (United States)

    Hu, Jun; Nie, Yangfan; Chen, Jianwei; Zhang, Yong; Wang, Zhichang; Fan, Qiwen; Yan, Xianghua

    2016-01-01

    Colonization of gut microbiota in mammals during the early life is vital to host health. The miniature piglet has recently been considered as an optimal infant model. However, less is known about the development of gut microbiota in miniature piglets. Here, this study was conducted to explore how the gut microbiota develops in weaned Congjiang miniature piglets. In contrast to the relatively stabilized gut fungal community, gut bacterial community showed a marked drop in alpha diversity, accompanied by significant alterations in taxonomic compositions. The relative abundances of 24 bacterial genera significantly declined, whereas the relative abundances of 7 bacterial genera (Fibrobacter, Collinsella, Roseburia, Prevotella, Dorea, Howardella, and Blautia) significantly increased with the age of weaned piglets. Fungal taxonomic analysis showed that the relative abundances of two genera (Kazachstania and Aureobasidium) significantly decreased, whereas the relative abundances of four genera (Aspergillus, Cladosporium, Simplicillium, and Candida) significantly increased as the piglets aged. Kazachstania telluris was the signature species predominated in gut fungal communities of weaned miniature piglets. The functional maturation of the gut bacterial community was characterized by the significantly increased digestive system, glycan biosynthesis and metabolism, and vitamin B biosynthesis as the piglets aged. These findings suggest that marked gut microbial changes in Congjiang miniature piglets may contribute to understand the potential gut microbiota development of weaned infants.

  4. Gradual Changes of Gut Microbiota in Weaned Miniature Piglets

    Science.gov (United States)

    Hu, Jun; Nie, Yangfan; Chen, Jianwei; Zhang, Yong; Wang, Zhichang; Fan, Qiwen; Yan, Xianghua

    2016-01-01

    Colonization of gut microbiota in mammals during the early life is vital to host health. The miniature piglet has recently been considered as an optimal infant model. However, less is known about the development of gut microbiota in miniature piglets. Here, this study was conducted to explore how the gut microbiota develops in weaned Congjiang miniature piglets. In contrast to the relatively stabilized gut fungal community, gut bacterial community showed a marked drop in alpha diversity, accompanied by significant alterations in taxonomic compositions. The relative abundances of 24 bacterial genera significantly declined, whereas the relative abundances of 7 bacterial genera (Fibrobacter, Collinsella, Roseburia, Prevotella, Dorea, Howardella, and Blautia) significantly increased with the age of weaned piglets. Fungal taxonomic analysis showed that the relative abundances of two genera (Kazachstania and Aureobasidium) significantly decreased, whereas the relative abundances of four genera (Aspergillus, Cladosporium, Simplicillium, and Candida) significantly increased as the piglets aged. Kazachstania telluris was the signature species predominated in gut fungal communities of weaned miniature piglets. The functional maturation of the gut bacterial community was characterized by the significantly increased digestive system, glycan biosynthesis and metabolism, and vitamin B biosynthesis as the piglets aged. These findings suggest that marked gut microbial changes in Congjiang miniature piglets may contribute to understand the potential gut microbiota development of weaned infants. PMID:27853453

  5. Determining the energetics of vicinal perovskite oxide surfaces

    NARCIS (Netherlands)

    Wessels, W.A.; Bollmann, Tjeerd Rogier Johannes; Koster, Gertjan; Zandvliet, Henricus J.W.; Rijnders, Augustinus J.H.M.

    2017-01-01

    The energetics of vicinal SrTiO3(001) and DyScO3(110), prototypical perovskite vicinal surfaces, has been studied using topographic atomic force microscopy imaging. The kink formation and strain relaxation energies are extracted from a statistical analysis of the step meandering. Both perovskite

  6. Some Properties of p-Curves, With an Application to Gradual Publication Bias.

    Science.gov (United States)

    Ulrich, Rolf; Miller, Jeff

    2017-04-20

    p-curves provide a useful window for peeking into the file drawer in a way that might reveal p-hacking (Simonsohn, Nelson, & Simmons, 2014a). The properties of p-curves are commonly investigated by computer simulations. On the basis of these simulations, it has been proposed that the skewness of this curve can be used as a diagnostic tool to decide whether the significant p values within a certain domain of research suggest the presence of p-hacking or actually demonstrate that there is a true effect. Here we introduce a rigorous mathematical approach that allows the properties of p-curves to be examined without simulations. This approach allows the computation of a p-curve for any statistic whose sampling distribution is known and thereby allows a thorough evaluation of its properties. For example, it shows under which conditions p-curves would exhibit the shape of a monotone decreasing function. In addition, we used weighted distribution functions to analyze how 2 different types of publication bias (i.e., cliff effects and gradual publication bias) influence the shapes of p-curves. The results of 2 survey experiments with more than 1,000 participants support the existence of a cliff effect at p = .05 and also suggest that researchers tend to be more likely to recommend submission of an article as the level of statistical significance increases beyond this p level. This gradual bias produces right-skewed p-curves mimicking the existence of real effects even when no such effects are actually present. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  7. From vicinal to rough crystal surfaces

    Science.gov (United States)

    Balibar, S.; Guthmann, C.; Rolley, E.

    1993-06-01

    One generally expects the properties of a vicinal surface to be independent of the existence of steps as soon as these steps overlap, i.e. when their mutual distance is smaller than their width. By using the roughening theory by Nozières and Gallet [1], we show that, at least for surfaces weakly coupled to the lattice, this overlap occurs for distances significantly larger than the commonly defined width. Our prediction is supported by an analysis of the various measurements of the angular variation of the surface stiffness of helium crystals, which were performed by Wolf et al. [2], Andreeva et al. [3] and Babkin et al. [4]. As a consequence, the interaction between crystal steps should be studied on vicinal surfaces with a much smaller tilt angle than previously thought. This article is also an opportunity to return to the relation between the step width and the correlation length on smooth surfaces, as well as to the treatment of the various finite size effects which occur in the problem of roughening. We finally reconsider how the weak coupling hypothesis applies to the case of helium crystals. On s'attend généralement à ce que les propriétés d'une surface vicinale ne soient plus contrôlées par l'existence des marches lorsque celles-ci se recouvrent, donc lorsque leur distance mutuelle devient inférieure à leur largeur. En reprenant la théorie de la transition rugueuse élaborée par Nozières et Gallet [1], nous montrons que, pour des surfaces faiblement couplées au réseau cristallin, ce recouvrement doit se produire pour des distances nettement plus grandes que la largeur (telle qu'elle est habituellement définie). Notre prédiction est confirmée par l'analyse des différentes mesures de la variation angulaire de la rigidité de surface des cristaux d'hélium réalisées par Wolf et al. [2], Andreeva et al. [3] and Babkin et al. [4]. Il s'ensuit que l'étude de l'interaction entre marches cristallines doit être effectuée sur des surfaces

  8. SINTESIS BAHAN UBAHAN GRADUAL ALUMINUM TITANAT/KORUNDUM DARI ALUMINA TRANSISI DENGAN PENAMBAHAN MgO

    Directory of Open Access Journals (Sweden)

    Achmad Sulhan Fauzi

    2013-03-01

    Full Text Available This article describes the results of research on the use of transition alumina for improving the performance of ceramics. Synthesis has been made of gradual changes materials (Functionally Graded Materials, FGM aluminum titanate (AT / corundum based on transition alumina powders with the addition of MgO as a stabilizer of AT as much as 2 wt.%. Samples without the addition of MgO was also made for comparison. Transition alumina with and without the addition of MgO were calcined at a temperature of 1100C for 1 hour to become ?-alumina. The powder mixture was compacted at a pressure of 49.3 MPa and then prasintered at a temperature of 1100C for 1 hour, then repeatedly infiltrated with infiltrator TiCl3 solution (20% which prepared by dissolving the Ti metal powders into HCl. Furthermore, the material sintered at temperatures of 1500C with a holding time for 3 hours. Physical character of materials showed an increase in density and decrease in porosity of the material due to the addition of MgO. Phase identification results obtained from the content of AT and corundum phases which gradual in depth, indicating that FGM has been formed. These results were supported by analysis of x-ray diffraction pattern showing the formation of a solid solution Al2 (1-x + MgxTi1 xO5 which marked by the shifting of the peak of AT phase in FGM samples with the addition of MgO. Tulisan ini menjelaskan hasil penelitian tentang penggunaan alumina transisi untuk meningkatkan performa keramik. Telah dilakukan sintesis bahan ubahan gradual (Functionally Graded Material, FGM aluminum titanat (AT/korundum berbahan dasar serbuk alumina transisi dengan penambahan MgO sebagai penstabil AT sebanyak 2 wt.%. Sampel tanpa tambahan MgO juga dibuat sebagai pembanding. Alumina transisi dengan dan tanpa penambahan MgO dikalsinasi pada temperatur 1100C selama 1 jam sehingga menjadi ?-alumina. Serbuk campuran dikompaksi pada tekanan 49,3 MPa lalu diprasinter pada temperatur 1100C selama

  9. Faults--Drakes Bay and Vicinity Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data of faults for the geologic and geomorphologic map of the Drakes Bay and Vicinity map area, California. The vector data file is...

  10. BackscatterB [EM300]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Monterey Canyon and Vicinity map area, California. Backscatter data are provided as separate...

  11. BackscatterC [7125]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Monterey Canyon and Vicinity map area, California. Backscatter data are provided as separate...

  12. Folds--Monterey Canyon and Vicinity Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the folds for the geologic and geomorphic map of Monterey Canyon and Vicinity, California. The vector data file is included in...

  13. Backscatter A [8101]--Drakes Bay and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Drakes bay and Vicinity map area, California. Backscatter data are provided as separate grids...

  14. Backscatter C [7125]--Drakes Bay and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Drakes bay and Vicinity map area, California. Backscatter data are provided as separate grids...

  15. Faults--Monterey Canyon and Vicinity Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the faults for the geologic and geomorphic map of Monterey Canyon and Vicinity, California. The vector data file is included in...

  16. establishment of background radiation dose rate in the vicinity

    African Journals Online (AJOL)

    nb

    .ac.tz). *Permanent address: Department of Physics, University of Dodoma. P. O. Box 339 Dodoma. ABSTRACT. The absorbed dose rate in air in the vicinity of the proposed Manyoni uranium mining project located in Singida region, Tanzania, ...

  17. Folds--Drakes Bay and Vicinity Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data of folds for the geologic and geomorphologic map of the Drakes Bay and Vicinity map area, California. The vector data file is...

  18. Paleoshorelines--Monterey Canyon and Vicinity Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the paleoshorelines for the geologic and geomorphic map of Monterey Canyon and Vicinity, California. The vector data file is...

  19. Aerial survey of sea otters in the Cordova vicinity

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The movement of significantly large numbers of sea otters into the Cordova vicinity has generated a local storm of protest concerning the ability of sea otters to...

  20. The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections.

    Directory of Open Access Journals (Sweden)

    Greta E Weiss

    2010-05-01

    Full Text Available Immunity to Plasmodium falciparum (Pf malaria is only acquired after years of repeated infections and wanes rapidly without ongoing parasite exposure. Antibodies are central to malaria immunity, yet little is known about the B-cell biology that underlies the inefficient acquisition of Pf-specific humoral immunity. This year-long prospective study in Mali of 185 individuals aged 2 to 25 years shows that Pf-specific memory B-cells and antibodies are acquired gradually in a stepwise fashion over years of repeated Pf exposure. Both Pf-specific memory B cells and antibody titers increased after acute malaria and then, after six months of decreased Pf exposure, contracted to a point slightly higher than pre-infection levels. This inefficient, stepwise expansion of both the Pf-specific memory B-cell and long-lived antibody compartments depends on Pf exposure rather than age, based on the comparator response to tetanus vaccination that was efficient and stable. These observations lend new insights into the cellular basis of the delayed acquisition of malaria immunity.

  1. Gradual extinction prevents the return of fear: Implications for the discovery of state

    Directory of Open Access Journals (Sweden)

    Samuel Joseph Gershman

    2013-11-01

    Full Text Available Fear memories are notoriously difficult to erase, often recovering over time. The longstanding explanation for this finding is that, in extinction training, a new memory is formed that competes with the old one for expression but does not otherwise modify it. This explanation is at odds with traditional models of learning such as Rescorla-Wagner and reinforcement learning. A possible reconciliation that was recently suggested is that extinction training leads to the inference of a new state that is different from the state that was in effect in the original training. This solution, however, raises a new question: under what conditions are new states, or new memories formed? Theoretical accounts implicate persistent large prediction errors in this process. As a test of this idea, we reasoned that careful design of the reinforcement schedule during extinction training could reduce these prediction errors enough to prevent the formation of a new memory, while still decreasing reinforcement sufficiently to drive modification of the old fear memory. In two Pavlovian fear-conditioning experiments, we show that gradually reducing the frequency of aversive stimuli, rather than eliminating them abruptly, prevents the recovery of fear. This finding has important implications for theories of state discovery in reinforcement learning.

  2. Temperature dependence of magnetic anisotropies in ultrathin Fe film on vicinal Si(111)

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yong-Sheng; He, Wei; Ye, Jun; Hu, Bo; Tang, Jin; Zhang, Xiang-Qun [State Key Laboratory of Magnetism and Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); Cheng, Zhao-Hua, E-mail: zhcheng@aphy.iphy.ac.cn [State Key Laboratory of Magnetism and Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); School of Physical Sciences, University of Chinese Academy of Sciences, Beijing 100190 (China)

    2017-05-01

    The temperature dependence of magnetic anisotropy of ultrathin Fe film with different thickness epitaxially grown on vicinal Si(111) substrate has been quantitatively investigated using the anisotropic magnetoresistance(AMR) measurements. Due to the effect of the vicinal substrate, the magnetic anisotropy is the superposition of a four-fold, a two-fold and a weakly six-fold contribution. It is found that the temperature dependence of the first-order magnetocrystalline anisotropies coefficient follows power laws of the reduced magnetization m(T)(=M(T)/M(0)) being consistent with the Callen and Callen's theory. However the temperature dependence of uniaxial magnetic anisotropy (UMA) shows novel behavior that decreases roughly as a function of temperature with different power law for samples with different thickness. We also found that the six-fold magnetocrystalline anisotropy is almost invariable over a wide temperature range. Possible mechanisms leading to the different exponents are discussed.

  3. Submesoscale Dispersion in the Vicinity of the Deepwater Horizon Spill

    Science.gov (United States)

    2014-09-02

    RESPONSIBLE PERSON 19b. TELEPHONE NUMBER (Include area code) 11-03-2014 Journal Article Submesoscale dispersion in the vicinity of the Deepwater ...ecosystems, society, and the economy as evidenced by the Deepwater Horizon oil spill in the Gulf of Mexico in 2010 and the Fukushima nuclear plant...vicinity of the Deepwater Horizon spill Andrew C. Pojea, Tamay M. Özgökmenb,1, Bruce L. Lipphardt, Jr.c, Brian K. Hausb, Edward H. Ryanb, Angelique C

  4. Erythrocyte membranes from slaughterhouse blood as potential drug vehicles: Isolation by gradual hypotonic hemolysis and biochemical and morphological characterization.

    Science.gov (United States)

    Kostić, Ivana T; Ilić, Vesna Lj; Đorđević, Verica B; Bukara, Katarina M; Mojsilović, Slavko B; Nedović, Viktor A; Bugarski, Diana S; Veljović, Đorđe N; Mišić, Danijela M; Bugarski, Branko M

    2014-10-01

    The present study was aimed at investigating the effect of isolation process-gradual hypotonic hemolysis on chosen parameters of the erythrocyte membranes (ghosts) originating from bovine and porcine slaughterhouse blood. The estimation of the gradual hypotonic hemolysis as a drug loading procedure for the erythrocyte ghosts was performed as well. Based on the results derived from analysis of the osmotic properties of the erythrocytes, the gradual hemolysis was performed with high volume of erythrocytes and 35mM hypotonic sodium-phosphate/NaCl, enabling >90% of hemolysis for both types of erythrocytes. Detailed insight into ghosts' morphology by field emission-scanning electron microscopy revealed a distortion from erythrocyte shape and an altered surface texture with increased bilayer curvature for both samples. Compared to erythrocytes, an average diameter of ghosts from both type of erythrocytes decreased for only about 10%. The reported unidispersity of the isolated ghosts is of great importance for their potential application as vehicles of active compounds. Gradual hemolysis did not lead to substantial loss of cholesterol and membrane/cytoskeleton proteins. This result indicated the ghosts' possibility to mimic the chemical and structural anisotropic environment of in vivo cell membranes, which is of significance for drug diffusion and partition coefficients. Induced shift of phosphatidylserine to external surface of the ghosts demonstrated their potential application as vehicles for targeted drug delivery to cells of reticuloendothelial system. Ultra high-performance liquid chromatography and Fourier transform infrared spectroscopy revealed the presence of a drug model - dexamethasone-sodium phosphate, and its interaction with structural components in both types of erythrocyte ghosts. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Gradual stiffness versus magnetic imaging-guided variable stiffness colonoscopes: A randomized noninferiority trial.

    Science.gov (United States)

    Garborg, Kjetil; Wiig, Håvard; Hasund, Audun; Matre, Jon; Holme, Øyvind; Noraberg, Geir; Løberg, Magnus; Kalager, Mette; Adami, Hans-Olov; Bretthauer, Michael

    2017-02-01

    Colonoscopes with gradual stiffness have recently been developed to enhance cecal intubation. We aimed to determine if the performance of gradual stiffness colonoscopes is noninferior to that of magnetic endoscopic imaging (MEI)-guided variable stiffness colonoscopes. Consecutive patients were randomized to screening colonoscopy with Fujifilm gradual stiffness or Olympus MEI-guided variable stiffness colonoscopes. The primary endpoint was cecal intubation rate (noninferiority limit 5%). Secondary endpoints included cecal intubation time. We estimated absolute risk differences with 95% confidence intervals (CIs). We enrolled 475 patients: 222 randomized to the gradual stiffness instrument, and 253 to the MEI-guided variable stiffness instrument. Cecal intubation rate was 91.7% in the gradual stiffness group versus 95.6% in the variable stiffness group. The adjusted absolute risk for cecal intubation failure was 4.3% higher in the gradual stiffness group than in the variable stiffness group (upper CI border 8.1%). Median cecal intubation time was 13 minutes in the gradual stiffness group and 10 minutes in the variable stiffness group (p < 0.001). The study is inconclusive with regard to noninferiority because the 95% CI for the difference in cecal intubation rate between the groups crosses the noninferiority margin. (ClinicalTrials.gov identifier: NCT01895504).

  6. MAJOR OIL PLAYS IN UTAH AND VICINITY

    Energy Technology Data Exchange (ETDEWEB)

    Thomas C. Chidsey; Craig D. Morgan; Kevin McClure; Grant C. Willis

    2003-09-01

    Arizona. Outcrop analogs are found in the stratigraphically equivalent Navajo Sandstone of southern Utah which displays large-scale dunal cross-strata with excellent reservoir properties and interdunal features such as oases, wadi, and playa lithofacies with poor reservoir properties. Hydrocarbons in the Paradox Formation are stratigraphically trapped in carbonate buildups (or phylloid-algal mounds). Similar carbonate buildups are exposed in the Paradox along the San Juan River of southeastern Utah. Reservoir-quality porosity may develop in the types of facies associated with buildups such as troughs, detrital wedges, and fans, identified from these outcrops. When combined with subsurface geological and production data, these outcrop analogs can improve (1) development drilling and production strategies such as horizontal drilling, (2) reservoir-simulation models, (3) reserve calculations, and (4) design and implementation of secondary/tertiary oil recovery programs and other best practices used in the oil fields of Utah and vicinity. During this quarter, technology transfer activities consisted of exhibiting the project plans, objectives, and products at a booth at the 2003 annual convention of the American Association of Petroleum Geologists. The project home page was updated on the Utah Geological Survey Internet web site.

  7. Major Oil Plays in Utah and Vicinity

    Energy Technology Data Exchange (ETDEWEB)

    Thomas C. Chidsey; Craig D. Morgan; Kevin McClure; Douglas A. Sprinkel; Roger L. Bon; Hellmut H. Doelling

    2003-12-31

    fractured and sealed by overlying argillaceous and non-fractured units. The best outcrop analogs for Twin Creek reservoirs are found at Devils Slide and near the town of Peoa, Utah, where fractures in dense, homogeneous non-porous limestone beds are in contact with the basal siltstone units (containing sealed fractures) of the overlying units. The shallow marine, Mississippian Leadville Limestone is a major oil and gas reservoir in the Paradox Basin of Utah and Colorado. Hydrocarbons are produced from basement-involved, northwest-trending structural traps with closure on both anticlines and faults. Excellent outcrops of Leadville-equivalent rocks are found along the south flank of the Uinta Mountains, Utah. For example, like the Leadville, the Mississippian Madison Limestone contains zones of solution breccia, fractures, and facies variations. When combined with subsurface geological and production data, these outcrop analogs can improve (1) development drilling and production strategies such as horizontal drilling, (2) reservoir-simulation models, (3) reserve calculations, and (4) design and implementation of secondary/tertiary oil recovery programs and other best practices used in the oil fields of Utah and vicinity. In the southern Green River Formation play of the Uinta Basin, optimal drilling, development, and production practices consist of: (1) owning drilling rigs and frac holding tanks; (2) perforating sandstone beds with more than 8 percent neutron porosity and stimulate with separate fracture treatments; (3) placing completed wells on primary production using artificial lift; (4) converting wells relatively soon to secondary waterflooding maintaining reservoir pressure above the bubble point to maximize oil recovery; (5) developing waterflood units using an alternating injector--producer pattern on 40-acre (16-ha) spacing; and (6) recompleting producing wells by perforating all beds that are productive in the waterflood unit. As part of technology transfer

  8. Analysis and asynchronous detection of gradually unfolding errors during monitoring tasks

    Science.gov (United States)

    Omedes, Jason; Iturrate, Iñaki; Minguez, Javier; Montesano, Luis

    2015-10-01

    Human studies on cognitive control processes rely on tasks involving sudden-onset stimuli, which allow the analysis of these neural imprints to be time-locked and relative to the stimuli onset. Human perceptual decisions, however, comprise continuous processes where evidence accumulates until reaching a boundary. Surpassing the boundary leads to a decision where measured brain responses are associated to an internal, unknown onset. The lack of this onset for gradual stimuli hinders both the analyses of brain activity and the training of detectors. This paper studies electroencephalographic (EEG)-measurable signatures of human processing for sudden and gradual cognitive processes represented as a trajectory mismatch under a monitoring task. Time-locked potentials and brain-source analysis of the EEG of sudden mismatches revealed the typical components of event-related potentials and the involvement of brain structures related to cognitive control processing. For gradual mismatch events, time-locked analyses did not show any discernible EEG scalp pattern, despite related brain areas being, to a lesser extent, activated. However, and thanks to the use of non-linear pattern recognition algorithms, it is possible to train an asynchronous detector on sudden events and use it to detect gradual mismatches, as well as obtaining an estimate of their unknown onset. Post-hoc time-locked scalp and brain-source analyses revealed that the EEG patterns of detected gradual mismatches originated in brain areas related to cognitive control processing. This indicates that gradual events induce latency in the evaluation process but that similar brain mechanisms are present in sudden and gradual mismatch events. Furthermore, the proposed asynchronous detection model widens the scope of applications of brain-machine interfaces to other gradual processes.

  9. Radiolarians Decreased Silicification as an Evolutionary Response to Reduced Cenozoic Ocean Silica Availability

    National Research Council Canada - National Science Library

    David B. Lazarus; Benjamin Kotrc; Gerwin Wulf; Daniela N. Schmidt; Steven M. Stanley

    2009-01-01

    .... Gradually decreasing Cenozoic radiolarian shell weight, by contrast, suggests that competition for dissolved silica, a shared nutrient, resulted in biologic coevolution between radiolaria and marine...

  10. The Effect of Gradual Increase in Contextual Interference on Acquisition, Retention and Transfer of Volleyball Skills

    Directory of Open Access Journals (Sweden)

    Fatemeh Pasand

    2016-04-01

    Full Text Available Background: A general viewpoint on contextual interference shows that a blocked practice schedule facilitates the acquisition of a skill while a random practice is more useful in the retention and transfer of that skill. Objective: The aim of this study was to investigate the effect of gradual increase in contextual interference upon acquisition, retention and transfer of volleyball skills. Methods: For this purpose, 45 participants were randomly selected from male students at Shiraz University-Iran. After pre-test, the participants were equally distributed in three experimental groups: blocked (low CI, random (high CI and percentile gradual increase. After nine training sessions and recording the scores, the students were tested for acquisition, retention and transfer. p≤0.05 was considered as significance level in all the tests. Results: There was significant difference between the groups in acquisition sessions in favor of the blocked group. Retention and transfer test results also showed a significant difference between the groups in favor of random training and gradual increase groups compared to blocked training group .However no significant difference was observed between random with gradual increase training groups. Conclusion: According to the findings of this research, it can be concluded that random and gradual increase in contextual interference training methods may increase the performance of subjects in terms of volleyball skills in retention and transfer tests. Keywords: Gradual Increase of Contextual Interference, Blocked, Random, Volleyball, Acquisition, Retention, Transfer

  11. Parkinson’s Disease Differentially Affects Adaptation to Gradual as Compared to Sudden Visuomotor Distortions

    Science.gov (United States)

    Venkatakrishnan, Anusha; Banquet, Jean P.; Burnod, Yves; Contreras-Vidal, José L.

    2011-01-01

    Patients with Parkinson’s disease (PD) have difficulties in movement adaptation to optimize performance in novel environmental contexts such as altered screen cursor-hand relationships. Prior studies have shown that the time course of the distortion differentially affects visuomotor adaptation to screen cursor rotations, suggesting separate mechanisms for gradual and sudden adaptation. Moreover, studies in human and non-human primates suggest that adaptation to sudden kinematic distortions may engage the basal ganglia, whereas adaptation to gradual kinematic distortions involves cerebellar structures. In the present studies, participants were patients with PD, who performed center-out pointing movements, using either a digitizer tablet and pen or a computer trackball, under normal or rotated screen cursor feedback conditions. The initial study tested patients with PD using a cross-over experimental design for adaptation to gradual as compared with sudden rotated hand-screen cursor relationships and revealed significant after-effects for the gradual adaptation task only. Consistent with these results, findings from a follow-up experiment using a trackball that required only small finger movements showed that patients with PD adapt better to gradual as against sudden perturbations, when compared to age-matched healthy controls. We conclude that Parkinson’s disease affects adaptation to sudden visuomotor distortions but spares adaptation to gradual distortions. PMID:21414678

  12. Gradual decline in mobility with the adoption of food production in Europe.

    Science.gov (United States)

    Ruff, Christopher B; Holt, Brigitte; Niskanen, Markku; Sladek, Vladimir; Berner, Margit; Garofalo, Evan; Garvin, Heather M; Hora, Martin; Junno, Juho-Antti; Schuplerova, Eliska; Vilkama, Rosa; Whittey, Erin

    2015-06-09

    Increased sedentism during the Holocene has been proposed as a major cause of decreased skeletal robusticity (bone strength relative to body size) in modern humans. When and why declining mobility occurred has profound implications for reconstructing past population history and health, but it has proven difficult to characterize archaeologically. In this study we evaluate temporal trends in relative strength of the upper and lower limb bones in a sample of 1,842 individuals from across Europe extending from the Upper Paleolithic [11,000-33,000 calibrated years (Cal y) B.P.] through the 20th century. A large decline in anteroposterior bending strength of the femur and tibia occurs beginning in the Neolithic (∼ 4,000-7,000 Cal y B.P.) and continues through the Iron/Roman period (∼ 2,000 Cal y B.P.), with no subsequent directional change. Declines in mediolateral bending strength of the lower limb bones and strength of the humerus are much smaller and less consistent. Together these results strongly implicate declining mobility as the specific behavioral factor underlying these changes. Mobility levels first declined at the onset of food production, but the transition to a more sedentary lifestyle was gradual, extending through later agricultural intensification. This finding only partially supports models that tie increased sedentism to a relatively abrupt Neolithic Demographic Transition in Europe. The lack of subsequent change in relative bone strength indicates that increasing mechanization and urbanization had only relatively small effects on skeletal robusticity, suggesting that moderate changes in activity level are not sufficient stimuli for bone deposition or resorption.

  13. One-shot versus gradual dilation technique for tract creation in percutaneous nephrolithotomy: a systematic review and meta-analysis.

    Science.gov (United States)

    Li, Yutao; Yang, Lu; Xu, Peng; Shen, Pengfei; Qian, Shengqiang; Wei, Wuran; Wang, Jia

    2013-10-01

    The aim of this study is to evaluate the efficacy and safety of one-shot versus gradual dilation technique for tract creation in percutaneous nephrolithotomy (PCNL). A systematic research of Pubmed, Embase and the Cochrane Library was performed to identify all relevant studies. The quality of the included trials was assessed and the data were extracted independently by two reviewers. The Cochrane Collaboration's Review Manager (RevMan) 5.0.2 software was used for statistical analysis. Four randomized controlled trials were included in analysis involving 346 patients in total. Of these patients 174 were in the one-shot group and 172 in the gradual group. Our meta-analysis showed that there were no significant differences in successful dilation rate [risk ratio (RR): 0.96; 95 % confidence interval (CI): 0.92-1.00, p = 0.05], transfusion rate (RR: 0.62; 95 % CI: 0.20-1.96; p = 0.42), and hemoglobin decrease [mean difference (MD): -0.34; 95 % CI: from -0.67 to -0.00; p = 0.05] between one-shot dilation and gradual dilation. One-shot dilation had significant shorter access time (MD: -1.03; 95 % CI: from -1.57 to -0.49; p = 0.0002) and X-ray exposure time (MD: -42.71; 95 % CI: from -45.05 to -40.37; p dilation. Our results show that One-shot dilation is an effective and safe procedure for tract creation in PCNL, with shorter access time and X-ray exposure time and without increased complications. As only four studies with small study populations were available, more high-quality larger trials with longer follow-up are recommended.

  14. Tissue specific responses alter the biomass accumulation in wheat under gradual and sudden salt stress

    Directory of Open Access Journals (Sweden)

    Yumurtaci A.

    2012-11-01

    Full Text Available Salinity is one the major limiting environmental factors which has negative side effects on crop production. The purpose of this study was to investigate the differences between the gradual and sudden salt stress effects on biomass accumulation associated with whole plant development in three different tissues of two wheat species ( Triticum aestivum and Triticum durum under hydroponic conditions in the long term. Considering the effects of sudden and gradual stress for biomass accumulation, while importance of salinity x genotype interaction for fresh weights was 5%, association for salinity x tissue type was found as 1% important. Interestingly, root branching and development of lateral roots were much more negatively affected by gradual stress rather than sudden salt application. Our results demonstrated that root and leaf were both critical tissues to test the salt tolerance by physiologically but sheath tissue might be used as an alternative source of variation for solving the interactions between root and leaves in wheat.

  15. Abrupt strategy change underlies gradual performance change: Bayesian hierarchical models of component and aggregate strategy use.

    Science.gov (United States)

    Wynton, Sarah K A; Anglim, Jeromy

    2017-10-01

    While researchers have often sought to understand the learning curve in terms of multiple component processes, few studies have measured and mathematically modeled these processes on a complex task. In particular, there remains a need to reconcile how abrupt changes in strategy use can co-occur with gradual changes in task completion time. Thus, the current study aimed to assess the degree to which strategy change was abrupt or gradual, and whether strategy aggregation could partially explain gradual performance change. It also aimed to show how Bayesian methods could be used to model the effect of practice on strategy use. To achieve these aims, 162 participants completed 15 blocks of practice on a complex computer-based task-the Wynton-Anglim booking (WAB) task. The task allowed for multiple component strategies (i.e., memory retrieval, information reduction, and insight) that could also be aggregated to a global measure of strategy use. Bayesian hierarchical models were used to compare abrupt and gradual functions of component and aggregate strategy use. Task completion time was well-modeled by a power function, and global strategy use explained substantial variance in performance. Change in component strategy use tended to be abrupt, whereas change in global strategy use was gradual and well-modeled by a power function. Thus, differential timing of component strategy shifts leads to gradual changes in overall strategy efficiency, and this provides one reason for why smooth learning curves can co-occur with abrupt changes in strategy use. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Bathymetry of the Republic of the Marshall Islands and vicinity

    Science.gov (United States)

    Hein, James R.; Wong, Florence L.; Mosier, Dan L.

    1999-01-01

    The bathymetric map of the Republic of the Marshall Islands and vicinity is bounded by a window of latitude 3 to 17 degrees North, longitude 153 to 175 degrees East. The map was compiled from surveys conducted by the USGS, Korean Ocean Research and Development Institute, and published gridded data. In addition to national jurisdictions, island and atoll coastlines are indicated on the map.

  17. Chemo- and Regioselective Oxidation of Secondary Alcohols in Vicinal Diols

    NARCIS (Netherlands)

    Eisink, Niek; Minnaard, Adriaan; Witte, Martin

    Oxidation of secondary hydroxyl groups in vicinal diols enables the straightforward functionalization of biomolecules and biomaterials. The resulting hydroxy ketone can for example be used to form derivatives, such as the epimeric alcohol and imines, and it may be employed for chemical probe

  18. Gradually-varied flow profiles in open channels analytical solutions by using Gaussian hypergeometric function

    CERN Document Server

    Jan, Chyan-Deng

    2014-01-01

    Gradually-varied flow (GVF) is a steady non-uniform flow in an open channel with gradual changes in its water surface elevation. The evaluation of GVF profiles under a specific flow discharge is very important in hydraulic engineering. This book proposes a novel approach to analytically solve the GVF profiles by using the direct integration and Gaussian hypergeometric function. Both normal-depth- and critical-depth-based dimensionless GVF profiles are presented. The novel approach has laid the foundation to compute at one sweep the GVF profiles in a series of sustaining and adverse channels, w

  19. Germany: of the nuclear energy expansion to the structure for their gradual abandonment; Alemania: de la expansion de la energia nuclear a la estructura para su abandono gradual

    Energy Technology Data Exchange (ETDEWEB)

    Mez, L. [Frei Universitat Berlin, Environmental Policy Research Centre, Thielallee 47, 14195 Berlin (Germany)

    2009-07-01

    This work exposes a panorama of the German nuclear industry, where the investment in this sector began around the fifty, having great peak during the period 1968 at 1989. Causes like a poor electricity demand, the over capacity and a persistent controversy among the public opinion for the nuclear energy use, stop the expansion from this industry to the little time of established. In contrast with the legal situation in most of the countries, in Germany the operation licences were granted without it limits of time. Nevertheless, the operation expectation was estimated inside a range of 20 to 40 years, depending in particular on the service life of the renovation parts. Taking into account these data, seven nuclear power plants of those that have already operated for 20 years or more, are about to confront expensive reconstructions or the closing in the following five years; while other seven will be closed in the subsequent 10 or 15 years. While the federal politicians and their directive went favorable until recent time in general to the extended use of nuclear energy, some authorities of the states became more restrictive when interpreting the allowed forecasts, what has generated continuous differences and regulatory uncertainty. In consequence, the facilities in operation gradually have shown interest in reaching agreements with the government about the nuclear politics, by means of the regulations reestablishment and one calculus linked at the costs. In spite of the many and constant judgments of the public opinion, the federal nuclear politics was up to 1998 on the side of the alliance pro nuclear and back to the industry by means of multiple fiscal and regulatory privileges. This official position was reverted by first time after the federal elections of that year, when a new red-green federal government announcement the gradual retirement of the nuclear energy of Germany. That coalition pact among the Democratic Social parties (red) and green

  20. Quantifying short run cost-effectiveness during a gradual implementation process

    NARCIS (Netherlands)

    Wetering, G. van de; Woertman, W.H.; Verbeek, A.L.M.; Broeders, M.J.M.; Adang, E.M.M.

    2013-01-01

    This paper examines the short run inefficiencies that arise during gradual implementation of a new cost-effective technology in healthcare. These inefficiencies arise when health gains associated with the new technology cannot be obtained immediately because the new technology does not yet supply

  1. Abrupt Strategy Change Underlies Gradual Performance Change: Bayesian Hierarchical Models of Component and Aggregate Strategy Use

    Science.gov (United States)

    Wynton, Sarah K. A.; Anglim, Jeromy

    2017-01-01

    While researchers have often sought to understand the learning curve in terms of multiple component processes, few studies have measured and mathematically modeled these processes on a complex task. In particular, there remains a need to reconcile how abrupt changes in strategy use can co-occur with gradual changes in task completion time. Thus,…

  2. Is conscious perception gradual or dichotomous? A comparison of report methodologies during a visual task

    DEFF Research Database (Denmark)

    Overgaard, M; Rote, J; Mouridsen, K

    2006-01-01

    In a recent article, [Sergent, C. & Dehaene, S. (2004). Is consciousness a gradual phenomenon? Evidence for an all-or-none bifurcation during the attentional blink, Psychological Science, 15(11), 720-729] claim to give experimental support to the thesis that there is a clear transition between...

  3. Gradually Adaptive Frameworks: Reasonable Disagreement and the Evolution of Evaluative Systems in Music Education

    Science.gov (United States)

    Haskins, Stanley

    2013-01-01

    The concept of "gradually adaptive frameworks" is introduced as a model with the potential to describe the evolution of belief evaluative systems through the consideration of reasonable arguments and evidence. This concept is demonstrated through an analysis of specific points of disagreement between David Elliott's praxial…

  4. Testing gradual and speciational models of evolution in extant taxa: the example of ratites

    NARCIS (Netherlands)

    Laurin, M.; Gussekloo, S.W.S.; Marjanovic, D.; Legendre, L.; Cubo, J.

    2012-01-01

    Ever since Eldredge and Gould proposed their model of punctuated equilibria, evolutionary biologists have debated how often this model is the best description of nature and how important it is compared to the more gradual models of evolution expected from natural selection and the neo-Darwinian

  5. Abrupt rather than gradual hormonal changes induce postpartum blues-like behavior in rats

    NARCIS (Netherlands)

    Doornbos, Bennard; Fokkema, Dirk S.; Molhoek, Margo; Tanke, Marit A. C.; Postema, Folkert; Korf, Jakob

    2009-01-01

    Aims: Postpartum blues is thought to be related to hormonal events accompanying delivery. We investigated whether blues-like symptoms depend on the rate of the decline of hormones, by comparing the behavioral consequences of an abrupt versus a gradual decline of gonadal hormones in an animal model.

  6. Responses of respiration and photosynthesis of Scenedesmus protuberans Fritsch to gradual and steep salinity increases

    NARCIS (Netherlands)

    Flameling, I.A.; Kromkamp, J.C.

    1994-01-01

    The effect of an increase in salinity on the physiology of the halotolerant chlorophyte Scenedesmus protuberans was studied in light-limited continuous cultures. It was observed that a gradual, as well as a steep increase in salinity resulted in lower biomass. However, the mechanisms by which this

  7. Modeling Effectiveness of Gradual Increases in Source Level to Mitigate Effects of Sonar on Marine Mammals

    NARCIS (Netherlands)

    Benda-Beckmann, A.M. von; Wensveen, P.J.; Kvadsheim, P.H.; Lam, F.P.A.; Miller, P.J.O.; Tyack, P.L.; Ainslie, M.A.

    2013-01-01

    Ramp-up or soft-start procedures (i.e., gradual increase in the source level) are used to mitigate the effect of sonar sound on marine mammals, although no one to date has tested whether ramp-up procedures are effective at reducing the effect of sound on marine mammals. We investigated the

  8. Locating spare part warehouses using the concept of gradual coverage - A case study

    DEFF Research Database (Denmark)

    Hansen, Klaus Reinholdt Nyhuus; Grunow, Martin

    2009-01-01

    In covering problems demand is usually covered by a facility, if it is less than a certain distance away., but if the distance is greater, none of the demand is covered. With gradual coverage, a fraction of the demand can be covered between an upper and lower distance. In this paper a case study ...

  9. A Cost-based Explanation of Gradual, Regional Internationalization of Multinationals on Social Networking Sites

    DEFF Research Database (Denmark)

    Pogrebnyakov, Nicolai

    2017-01-01

    This paper examines firm internationalization on social networking sites (SNS). It systematically examines costs faced by an internationalizing firm and how firms react to these costs according to “distance-dependent” (gradual and regional) and “distance-invariant” (born-global) explanations...

  10. Characterisation of the Whole Blood mRNA Transcriptome in Holstein-Friesian and Jersey Calves in Response to Gradual Weaning.

    Directory of Open Access Journals (Sweden)

    D Johnston

    Full Text Available Weaning of dairy calves is an early life husbandry management practice which involves the changeover from a liquid to a solid feed based diet. The objectives of the study were to use RNA-seq technology to examine the effect of (i breed and (ii gradual weaning, on the whole blood mRNA transcriptome of artificially reared Holstein-Friesian and Jersey calves. The calves were gradually weaned over 14 days (day (d -13 to d 0 and mRNA transcription was examined one day before gradual weaning was initiated (d -14, one day after weaning (d 1, and 8 days after weaning (d 8. On d -14, 550 genes were differentially expressed between Holstein-Friesian and Jersey calves, while there were 490 differentially expressed genes (DEG identified on d 1, and 411 DEG detected eight days after weaning (P 0.05. The pathways, gene ontology terms, and biological functions consistently over-represented among the DEG between Holstein-Friesian and Jersey were associated with the immune response and immune cell signalling, specifically chemotaxis. Decreased transcription of several cytokines, chemokines, immunoglobulin-like genes, phagocytosis-promoting receptors and g-protein coupled receptors suggests decreased monocyte, natural killer cell, and T lymphocyte, chemotaxis and activation in Jersey compared to Holstein-Friesian calves. Knowledge of breed-specific immune responses could facilitate health management practices better tailored towards specific disease sensitivities of Holstein-Friesian and Jersey calves. Gradual weaning did not compromise the welfare of artificially-reared dairy calves, evidenced by the lack of alterations in the expression of any genes in response to gradual weaning.

  11. Gradual Increase of miR156 Regulates Temporal Expression Changes of Numerous Genes during Leaf Development in Rice1[C][W][OA

    Science.gov (United States)

    Xie, Kabin; Shen, Jianqiang; Hou, Xin; Yao, Jialing; Li, Xianghua; Xiao, Jinghua; Xiong, Lizhong

    2012-01-01

    The highly conserved plant microRNA, miR156, is an essential regulator for plant development. In Arabidopsis (Arabidopsis thaliana), miR156 modulates phase changing through its temporal expression in the shoot. In contrast to the gradual decrease over time in the shoot (or whole plant), we found that the miR156 level in rice (Oryza sativa) gradually increased from young leaf to old leaf after the juvenile stage. However, the miR156-targeted rice SQUAMOSA-promoter binding-like (SPL) transcription factors were either dominantly expressed in young leaves or not changed over the time of leaf growth. A comparison of the transcriptomes of early-emerged old leaves and later-emerged young leaves from wild-type and miR156 overexpression (miR156-OE) rice lines found that expression levels of 3,008 genes were affected in miR156-OE leaves. Analysis of temporal expression changes of these genes suggested that miR156 regulates gene expression in a leaf age-dependent manner, and miR156-OE attenuated the temporal changes of 2,660 genes. Interestingly, seven conserved plant microRNAs also showed temporal changes from young to old leaves, and miR156-OE also attenuated the temporal changes of six microRNAs. Consistent with global gene expression changes, miR156-OE plants resulted in dramatic changes including precocious leaf maturation and rapid leaf/tiller initiation. Our results indicate that another gradient of miR156 is present over time, a gradual increase during leaf growth, in addition to the gradual decrease during shoot growth. Gradually increased miR156 expression in the leaf might be essential for regulating the temporal expression of genes involved in leaf development. PMID:22271747

  12. Evidence for Gradual External Reconnection Before Explosive Eruption of a Solar Filament

    Science.gov (United States)

    Sterling, Alphonse C.; Moore, Ronald L.

    2004-01-01

    We observe a slowly evolving quiet-region solar eruption of 1999 April 18, using extreme-ultraviolet (EUV) images from the EUV Imaging Telescope (EIT) on the Solar and Heliospheric Observatory (SOHO) and soft X-ray images from the Soft X-ray Telescope (SXT) on Yohkoh. Using difference images, in which an early image is subtracted from later images, we examine dimmings and brightenings in the region for evidence of the eruption mechanism. A filament rose slowly at about 1 km/s for 6 hours before being rapidly ejected at about 16 km/s leaving flare brightenings and postflare loops in its wake. Magnetograms from the Michelson Doppler Imager (MDI) on SOHO show that the eruption occurred in a large quadrupolar magnetic region with the filament located on the neutral line of the quadrupole s central inner lobe between the inner two of the four polarity domains. In step with the slow rise, subtle EIT dimmings commence and gradually increase over the two polarity domains on one side of the filament, i.e., in some of the loops of one of the two sidelobes of the quadrupole. Concurrently, soft X-ray brightenings gradually increase in both sidelobes. Both of these effects suggest heating in the sidelobe magnetic arcades. which gradually increase over several hours before the fast eruption. Also, during the slow pre- eruption phase, SXT dimmings gradually increase in the feet and legs of the central lobe, indicating expansion of the central-lobe magnetic arcade enveloping the filament. During the rapid ejection. these dimmings rapidly grow in darkness and in area, especially in the ends of the sigmoid field that erupts with the filament. and flare brightenings begin underneath the fast-moving but still low-altitude filament. We consider two models for explaining the eruption: "breakout. which says that reconnection occurs high above the filament prior to eruption, and tether cutting, which says that the eruption is unleashed by reconnection beneath the filament. The pre

  13. Radiation Field in the Vicinity of the Collider Center

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, A. J. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    1994-10-26

    The Collider Center and the adjoining cryogenic support building are unique among the buildings close to the collider tunnel because these are locations where the occupancy by non-radiation workers is high. This note describes calculations of the dose equivalent from local beam loss at both the nearest point of these buildings to the collider ring and on the berm in the vicinity of these buildings.

  14. Environmental surveillance in the vicinity of Hanford for January 1968

    Energy Technology Data Exchange (ETDEWEB)

    Wooldridge, C.B. (ed.)

    1968-04-15

    The concentrations of most radionuclides in the vicinity of Hanford during January 1968 were below comparable measurements for a year ago. Slightly increased concentrations of I-131 in Richland drinking water were observed during the last two weeks of the month. Radioiodine detected in several milk samples (maximum 25 pCi/l) was attributed to fallout from an announced nuclear weapons test of December 24, 1967. Increased beta activities on air filters were also attributed to fallout.

  15. Detecting gradual visual changes in colour and brightness agnosia: a double dissociation.

    Science.gov (United States)

    Nijboer, Tanja C W; te Pas, Susan F; van der Smagt, Maarten J

    2011-03-09

    Two patients, one with colour agnosia and one with brightness agnosia, performed a task that required the detection of gradual temporal changes in colour and brightness. The results for these patients, who showed anaverage or an above-average performance on several tasks designed to test low-level colour and luminance (contrast) perception in the spatial domain, yielded a double dissociation; the brightness agnosic patient was within the normal range for the coloured stimuli, but much slower to detect brightness differences, whereas the colour agnosic patient was within the normal range for the achromatic stimuli, but much slower for the coloured stimuli. These results suggest that a modality-specific impairment in the detection of gradual temporal changes might be related to, if not underlie, the phenomenon of visual agnosia.

  16. Computational issues of solving the 1D steady gradually varied flow equation

    Directory of Open Access Journals (Sweden)

    Artichowicz Wojciech

    2014-09-01

    Full Text Available In this paper a problem of multiple solutions of steady gradually varied flow equation in the form of the ordinary differential energy equation is discussed from the viewpoint of its numerical solution. Using the Lipschitz theorem dealing with the uniqueness of solution of an initial value problem for the ordinary differential equation it was shown that the steady gradually varied flow equation can have more than one solution. This fact implies that the nonlinear algebraic equation approximating the ordinary differential energy equation, which additionally coincides with the wellknown standard step method usually applied for computing of the flow profile, can have variable number of roots. Consequently, more than one alternative solution corresponding to the same initial condition can be provided. Using this property it is possible to compute the water flow profile passing through the critical stage.

  17. Estudio transcultural con la prueba de Bender: Sistema de puntuación gradual (Cross-Cultural Study with Bender Test- Gradual Scoring System

    Directory of Open Access Journals (Sweden)

    Fabián Javier Marín Rueda

    2013-12-01

    Full Text Available RESUMEN: El objetivo del presente estudio es comparar el desempeño en la Prueba Gestáltica Visomotriz de Bender - Sistema de Puntuación Gradual (B-SPG en un grupo de niños peruanos en función a los datos ofrecidos por el manual brasilero de la prueba. Participaron 82 niños, de ambos sexos, con edades entre los 8 y 10 años (M = 9.21, DT = 0.83. Los niños provenían de los distritos de Pueblo Libre (43.9% y Rímac (51.2%, de la provincia de Lima, así como también de Lima Metropolitana (4.9%. El B-SPG fue aplicado de forma colectiva. Los promedios de puntos obtenidos por los niños peruanos en el B-SPG fueron significativamente superiores a los obtenidos por los niños brasileros en cada una de las edades estudiadas. Se destaca la importancia de investigar evidencias de validez y de confiabilidad para que la prueba pueda ser usada de forma adecuada en el Perú, considerando las particularidades de desarrollo de los niños del país. ABSTRACT: The objective of the study is to compare performance on the Bender Visual Motor Gestalt test - system of Gradual punctuation (B-SPG in a group of Peruvian children in connection with the data provided by the Brazilian manual of the test. In this research 82 Peruvian children were involved, both sexes, with ages between 8 and 10 years (M = 9.21, DT = 0.83. The hildren came from the districts of Pueblo Libre (43.9% and Rimac (51.2% in the province of Lima, as well as from metropolitan Lima (4.9%. The B-SPG was collectively applied in the children’s schools. The average points earned by the Peruvian children in the B-SPG were significantly higher than those obtained by Brazilian children in each one of the ages studied. It emphasizes the importance of investigating evidence of validity and reliability, so that, the test can be used appropriately in Peru, considering the peculiarities of the development of children in the country.

  18. Do Industries Lead the Stock Market? Gradual Diffusion of Information and Cross-Asset Return Predictability

    OpenAIRE

    Hong, Harrison; Torous, Walter; Valkanov, Rossen

    2002-01-01

    We test the hypothesis that the gradual diffusion of information across asset markets leads to cross-asset return predictability. Using thirty-four industry portfolios and the broad market index as our test assets, we establish several key results. First, a number of industries such as retail, services, commercial real estate, metal, and petroleum lead the stock market by up to two months. In contrast, the market, which is widely followed, only leads a few industries. Importantly, an industry...

  19. Gradually Increased Training Intensity Benefits Rehabilitation Outcome after Stroke by BDNF Upregulation and Stress Suppression

    Directory of Open Access Journals (Sweden)

    Jing Sun

    2014-01-01

    Full Text Available Physical training is necessary for effective rehabilitation in the early poststroke period. Animal studies commonly use fixed training intensity throughout rehabilitation and without adapting it to the animals' recovered motor ability. This study investigated the correlation between training intensity and rehabilitation efficacy by using a focal ischemic stroke rat model. Eighty male Sprague-Dawley rats were induced with middle cerebral artery occlusion/reperfusion surgery. Sixty rats with successful stroke were then randomly assigned into four groups: control (CG, n=15, low intensity (LG, n=15, gradually increased intensity (GIG, n=15, and high intensity (HG, n=15. Behavioral tests were conducted daily to evaluate motor function recovery. Stress level and neural recovery were evaluated via plasma corticosterone and brain-derived neurotrophic factor (BDNF concentration, respectively. GIG rats significantly (P<0.05 recovered motor function and produced higher hippocampal BDNF (112.87 ± 25.18 ng/g. GIG and LG rats exhibited similar stress levels (540.63 ± 117.40 nM/L and 508.07 ± 161.30 nM/L, resp., which were significantly lower (P<0.05 than that (716.90 ± 156.48 nM/L of HG rats. Training with gradually increased intensity achieved better recovery with lower stress. Our observations indicate that a training protocol that includes gradually increasing training intensity should be considered in both animal and clinical studies for better stroke recovery.

  20. Testing gradual and speciational models of evolution in extant taxa: the example of ratites.

    Science.gov (United States)

    Laurin, M; Gussekloo, S W S; Marjanović, D; Legendre, L; Cubo, J

    2012-02-01

    Ever since Eldredge and Gould proposed their model of punctuated equilibria, evolutionary biologists have debated how often this model is the best description of nature and how important it is compared to the more gradual models of evolution expected from natural selection and the neo-Darwinian paradigm. Recently, Cubo proposed a method to test whether morphological data in extant ratites are more compatible with a gradual or with a speciational model (close to the punctuated equilibrium model). As shown by our simulations, a new method to test the mode of evolution of characters (involving regression of standardized contrasts on their expected standard deviation) is easier to implement and more powerful than the previously proposed method, but the Mesquite module comet (aimed at investigating evolutionary models using comparative data) performs better still. Uncertainties in branch length estimates are probably the largest source of potential error. Cubo hypothesized that heterochronic mechanisms may underlie morphological changes in bone shape during the evolution of ratites. He predicted that the outcome of these changes may be consistent with a speciational model of character evolution because heterochronic changes can be instantaneous in terms of geological time. Analysis of a more extensive data set confirms his prediction despite branch length uncertainties: evolution in ratites has been mostly speciational for shape-related characters. However, it has been mostly gradual for size-related ones. © 2011 The Authors. Journal of Evolutionary Biology © 2011 European Society For Evolutionary Biology.

  1. Interacting Learning Processes during Skill Acquisition: Learning to control with gradually changing system dynamics.

    Science.gov (United States)

    Ludolph, Nicolas; Giese, Martin A; Ilg, Winfried

    2017-10-16

    There is increasing evidence that sensorimotor learning under real-life conditions relies on a composition of several learning processes. Nevertheless, most studies examine learning behaviour in relation to one specific learning mechanism. In this study, we examined the interaction between reward-based skill acquisition and motor adaptation to changes of object dynamics. Thirty healthy subjects, split into two groups, acquired the skill of balancing a pole on a cart in virtual reality. In one group, we gradually increased the gravity, making the task easier in the beginning and more difficult towards the end. In the second group, subjects had to acquire the skill on the maximum, most difficult gravity level. We hypothesized that the gradual increase in gravity during skill acquisition supports learning despite the necessary adjustments to changes in cart-pole dynamics. We found that the gradual group benefits from the slow increment, although overall improvement was interrupted by the changes in gravity and resulting system dynamics, which caused short-term degradations in performance and timing of actions. In conclusion, our results deliver evidence for an interaction of reward-based skill acquisition and motor adaptation processes, which indicates the importance of both processes for the development of optimized skill acquisition schedules.

  2. Sudden or Gradual Sound Onset Differentially Affects Audiogenic Seizure Severity in Developmentally Primed Rats

    Directory of Open Access Journals (Sweden)

    Mark Zrull

    2005-01-01

    Full Text Available In a rat model of reflex epilepsy, sound-induced or audiogenic seizures (AGS are initiated by and propagated though excessive activity of inferior colliculus neurons. Because more auditory system neurons respond to onset of sound rather than a continuing sound, we examined the effect of sudden (SO and gradual (GO onset intensity of seizure-triggering sound on AGS severity. Long-Evans rats were primed for AGS using loud sound when they were 18 days old and were tested for seizures using loud noise when 32 days old. SO and GO groups of 10 rats, matched for AGS severity, were then tested three times for AGS. Overall, rated seizure activity was 39% more severe in GO than SO rats (p<.05, and the duration of clonus for GO animals was 28% longer than for SO rats (p<.05. While latency to clonic seizures was 24% longer in GO than SO rats, this was an artifact of the sound gradually reaching AGS-inducing intensity for the GO group. Because sensory neurons respond to change, sudden onset sound may allow more adaptation of AGS-prone inferior colliculus neurons than a gradual onset seizure-inducing stimulus. Ramping to a maximum intensity sound may produce greater seizure severity due to a greater number of neurons remaining active.

  3. Sudden or gradual sound onset differentially effects audiogenic seizure severity in developmentally primed rats

    Directory of Open Access Journals (Sweden)

    Mary Dravland

    2005-08-01

    Full Text Available In a rat model of reflex epilepsy, sound-induced or audiogenic seizures (AGS are initiated by and propagated though excessive activity of inferior colliculus neurons. Because more auditory system neurons respond to onset of than a continuing sound, we examined the effect of sudden (SO and gradual (GO onset intensity of seizure-triggering sound on AGS severity. Long-Evans rats were primed for AGS using loud sound when they were 18 days old and were tested for seizures using loud noise when 32 days old. SO and GO groups of 10 rats, matched for AGS severity, were then tested 3 times for AGS. Overall, rated seizure activity was 39% more severe in GO than SO rats (p<.05, and the duration of clonus for GO animals was 28% longer than for SO rats (p<.05. While latency to clonic seizures was 24% longer in GO than SO rats, this was an artifact of the sound gradually reaching AGS-inducing intensity for the GO group. Because sensory neurons respond to change, sudden onset sound may allow more adaptation of AGSprone inferior colliculus neurons than a gradual onset seizure-inducing stimulus. Ramping to a maximum intensity sound may produce greater seizure severity due to a greater number of neurons remaining.

  4. Chronic environmental stress enhances tolerance to seasonal gradual warming in marine mussels.

    Directory of Open Access Journals (Sweden)

    Ionan Marigómez

    Full Text Available In global climate change scenarios, seawater warming acts in concert with multiple stress sources, which may enhance the susceptibility of marine biota to thermal stress. Here, the responsiveness to seasonal gradual warming was investigated in temperate mussels from a chronically stressed population in comparison with a healthy one. Stressed and healthy mussels were subjected to gradual temperature elevation for 8 days (1°C per day; fall: 16-24°C, winter: 12-20°C, summer: 20-28°C and kept at elevated temperature for 3 weeks. Healthy mussels experienced thermal stress and entered the time-limited survival period in the fall, became acclimated in winter and exhibited sublethal damage in summer. In stressed mussels, thermal stress and subsequent health deterioration were elicited in the fall but no transition into the critical period of time-limited survival was observed. Stressed mussels did not become acclimated to 20°C in winter, when they experienced low-to-moderate thermal stress, and did not experience sublethal damage at 28°C in summer, showing instead signs of metabolic rate depression. Overall, although the thermal threshold was lowered in chronically stressed mussels, they exhibited enhanced tolerance to seasonal gradual warming, especially in summer. These results challenge current assumptions on the susceptibility of marine biota to the interactive effects of seawater warming and pollution.

  5. Chronic environmental stress enhances tolerance to seasonal gradual warming in marine mussels.

    Science.gov (United States)

    Marigómez, Ionan; Múgica, Maria; Izagirre, Urtzi; Sokolova, Inna M

    2017-01-01

    In global climate change scenarios, seawater warming acts in concert with multiple stress sources, which may enhance the susceptibility of marine biota to thermal stress. Here, the responsiveness to seasonal gradual warming was investigated in temperate mussels from a chronically stressed population in comparison with a healthy one. Stressed and healthy mussels were subjected to gradual temperature elevation for 8 days (1°C per day; fall: 16-24°C, winter: 12-20°C, summer: 20-28°C) and kept at elevated temperature for 3 weeks. Healthy mussels experienced thermal stress and entered the time-limited survival period in the fall, became acclimated in winter and exhibited sublethal damage in summer. In stressed mussels, thermal stress and subsequent health deterioration were elicited in the fall but no transition into the critical period of time-limited survival was observed. Stressed mussels did not become acclimated to 20°C in winter, when they experienced low-to-moderate thermal stress, and did not experience sublethal damage at 28°C in summer, showing instead signs of metabolic rate depression. Overall, although the thermal threshold was lowered in chronically stressed mussels, they exhibited enhanced tolerance to seasonal gradual warming, especially in summer. These results challenge current assumptions on the susceptibility of marine biota to the interactive effects of seawater warming and pollution.

  6. Kinetics and mechanism of the oxidation of some vicinal and non ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 115; Issue 2. Kinetics and ... Kinetics of oxidation of five vicinal and four non-vicinal diols, and two of their monoethers, by tetrabutylammonium tribromide (TBATB) has been studied. The vicinal diols ... Department of Chemistry, JNV University, Jodhpur 342 005, India ...

  7. Tracking an electronic wave packet in the vicinity of a conical intersection

    Science.gov (United States)

    Qi, Da-Long; Duan, Hong-Guang; Sun, Zhen-Rong; Miller, R. J. Dwayne; Thorwart, Michael

    2017-08-01

    This work treats the impact of vibrational coherence on the quantum efficiency of a dissipative electronic wave packet in the vicinity of a conical intersection by monitoring the time-dependent wave packet projection onto the tuning and the coupling mode. The vibrational coherence of the wave packet is tuned by varying the strength of the dissipative vibrational coupling of the tuning and the coupling modes to their thermal baths. We observe that the most coherent wave packet yields a quantum efficiency of 93%, but with a large transfer time constant. The quantum yield is dramatically decreased to 50% for a strongly damped incoherent wave packet, but the associated transfer time of the strongly localized wave packet is short. In addition, we find for the strongly damped wave packet that the transfer occurs via tunneling of the wave packet between the potential energy surfaces before the seam of the conical intersection is reached and a direct passage takes over. Our results provide direct evidence that vibrational coherence of the electronic wave packet is a decisive factor which determines the dynamical behavior of a wave packet in the vicinity of the conical intersection.

  8. Effects of gradual falling environmental temperature on blood glucose and total serum cholesterol levels of the common Indian frog-Rana tigrina

    Energy Technology Data Exchange (ETDEWEB)

    Govil, S.C. (C.M.Sc. College, Darbhanga (India))

    The effects of a gradual decrease in temperature from 30{degree}C (controlled condition) to 25{degree}C, 20{degree}C, 15{degree}C and 10{degree}C on the levels of blood glucose and total serum cholesterol were studied in both sexes of Rana tigrina. It was found that the gradual fall in temperature caused a successive and significant rise in the levels of blood glucose and total serum cholesterol leading to hyperglycemia and hypercholesterolemia respectively in both sexes. It appears that both conditions were due to cold stress which stimulated the adrenal gland thus leading to production of epinephrine. The above mentioned conditions caused other physiopathological disturbances. It is suggested that these conditions may cause hibernation in this animal.

  9. The ketogenic diet: initiation at goal calories versus gradual caloric advancement.

    Science.gov (United States)

    Bansal, Seema; Cramp, Laura; Blalock, Dan; Zelleke, Tesfaye; Carpenter, Jessica; Kao, Amy

    2014-01-01

    Inpatient initiation of the ketogenic diet has historically involved fasting followed by gradual advancement of calories and/or diet ratio. Complications during this initiation period are common. We sought to determine if the initiation of the diet at goal calories would reduce these complications while maintaining efficacy. Sixty patients were admitted to a tertiary care hospital for elective initiation of the ketogenic diet between October 2007 and January 2013. All patients were placed on a ketogenic diet initiation pathway. In 2010, the pathway was modified from gradual caloric advancement to initiation at goal calories. We selected 30 consecutive patients before and after the change for comparison. Each child's record was reviewed for the occurrence of hypoglycemia, number of days to reach full ketosis (defined as 4 + urine ketones), acidosis requiring commencement of sodium citrate, length of admission, and long-term efficacy. Both methods of initiation had similar rates of dehydration, vomiting, lethargy, and irritability. More patients initiated at goal received sodium citrate (P = 0.005); however, mean daily values of carbon dioxide were not significantly different. Onset of ketosis was slightly delayed (P = 0.009) in patients initiated at goal, but length of stay was not affected (P > 0.1). Hypoglycemia was uncommon and rates were similar between the groups. Efficacy at 3 months was better in patients initiated at full calories (P ketogenic diet full calories is a reasonable alternative to the current standard practice of gradual advancement of calories and/or diet ratio. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. An arterio-venous bridge for gradual weaning from adult veno-arterial extracorporeal life support.

    Science.gov (United States)

    Babar, Z U D; Sharma, A S; Ganushchak, Y M; Delnoij, T S R; Donker, D W; Maessen, J G; Weerwind, P W

    2015-11-01

    Weaning from extracorporeal life support (ELS) is particularly challenging when cardiac recovery is slow, largely incomplete and hard to predict. Therefore, we describe an individualized gradual weaning strategy using an arterio-venous (AV) bridge incorporated into the circuit to facilitate weaning. Thirty adult patients weaned from veno-arterial ELS using an AV bridge were retrospectively analyzed. Serial echocardiography and hemodynamic monitoring were used to assess cardiac recovery and load responsiveness. Upon early signs of myocardial recovery, an AV bridge with an Hoffman clamp was added to the circuit and weaning was initiated. Support flow was reduced stepwise by 10-15% every 2 to 8 hours while the circuit flow was maintained at 3.5-4.5 L/min. The AV bridge facilitated gradual weaning in all 30 patients (median age: 66 [53-71] years; 21 males) over a median period of 25 [8-32] hours, with a median support duration of 96 [31-181] hours. During weaning, the median left ventricular ejection fraction was 25% [15-32] and the median velocity time integral of the aortic valve was 16 cm [10-23]. Through the weaning period, the mean arterial blood pressure was maintained at 70 mmHg and the activated partial thromboplastin time was 60 ± 10 seconds without additional systemic heparinization. Neither macroscopic thrombus formation in the ELS circuit during and after weaning nor clinically relevant thromboembolism was observed. Incorporation of an AV bridge for weaning from veno-arterial ELS is safe and feasible to gradually wean patients with functional cardiac recovery without compromising the circuit integrity. © The Author(s) 2015.

  11. Social representations of climate change in Swedish lay focus groups: local or distant, gradual or catastrophic?

    Science.gov (United States)

    Wibeck, Victoria

    2014-02-01

    This paper explores social representations of climate change, investigating how climate change is discussed by Swedish laypeople interacting in focus group interviews. The analysis focuses on prototypical examples and metaphors, which were key devices for objectifying climate change representations. The paper analyzes how the interaction of focus group participants with other speakers, ideas, arguments, and broader social representations shaped their representations of climate change. Climate change was understood as a global but distant issue with severe consequences. There was a dynamic tension between representations of climate change as a gradual vs. unpredictable process. Implications for climate change communication are discussed.

  12. Gradual phase transition between the smectic- C* and smectic- CA* phases and the thresholdless antiferroelectricity

    OpenAIRE

    VIJ, JAGDISH; SONG, JANG-KUN; Fukuda, Atsuo

    2008-01-01

    PUBLISHED We have constructed the phase diagrams for a binary-mixture system of antiferroelectric and ferroelectric liquid-crystalline materials in both thick and thin cells. In the phase diagrams the boundary between the smectic-C* and smectic-CA * phases runs almost parallel to the temperature axis below from ca. 70 ?C down to at least ?25 ?C. The SmC*-SmCA * phase transition for a thin cell shows a large supercooling, and a gradual transition occurs near the boundary. ...

  13. Engineering web maps with gradual content zoom based on streaming vector data

    Science.gov (United States)

    Huang, Lina; Meijers, Martijn; Šuba, Radan; van Oosterom, Peter

    2016-04-01

    Vario-scale data structures have been designed to support gradual content zoom and the progressive transfer of vector data, for use with arbitrary map scales. The focus to date has been on the server side, especially on how to convert geographic data into the proposed vario-scale structures by means of automated generalisation. This paper contributes to the ongoing vario-scale research by focusing on the client side and communication, particularly on how this works in a web-services setting. It is claimed that these functionalities are urgently needed, as many web-based applications, both desktop and mobile, require gradual content zoom, progressive transfer and a high performance level. The web-client prototypes developed in this paper make it possible to assess the behaviour of vario-scale data and to determine how users will actually see the interactions. Several different options of web-services communication architectures are possible in a vario-scale setting. These options are analysed and tested with various web-client prototypes, with respect to functionality, ease of implementation and performance (amount of transmitted data and response times). We show that the vario-scale data structure can fit in with current web-based architectures and efforts to standardise map distribution on the internet. However, to maximise the benefits of vario-scale data, a client needs to be aware of this structure. When a client needs a map to be refined (by means of a gradual content zoom operation), only the 'missing' data will be requested. This data will be sent incrementally to the client from a server. In this way, the amount of data transferred at one time is reduced, shortening the transmission time. In addition to these conceptual architecture aspects, there are many implementation and tooling design decisions at play. These will also be elaborated on in this paper. Based on the experiments conducted, we conclude that the vario-scale approach indeed supports gradual

  14. Scheme Transformations in the Vicinity of an Infrared Fixed Point

    DEFF Research Database (Denmark)

    Ryttov, Thomas; Shrock, Robert

    2012-01-01

    We analyze the effect of scheme transformations in the vicinity of an exact or approximate infrared fixed point in an asymptotically free gauge theory with fermions. We show that there is far less freedom in carrying out such scheme transformations in this case than at an ultraviolet fixed point....... We construct a transformation from the $\\bar{MS}$ scheme to a scheme with a vanishing three-loop term in the $\\beta$ function and use this to assess the scheme dependence of an infrared fixed point in SU($N$) theories with fermions. Implications for the anomalous dimension of the fermion bilinear...

  15. A homogenous CS/NaCMC/n-HA polyelectrolyte complex membrane prepared by gradual electrostatic assembling.

    Science.gov (United States)

    Jiang, Hong; Zuo, Yi; Cheng, Lin; Wang, Hongli; Gu, Aiqun; Li, Yubao

    2011-02-01

    A homogenous membrane composed of chitosan (CS), sodium carboxymethyl cellulose (NaCMC) and nano hydroxyapatite (n-HA) was prepared by a gradual electrostatic assembling (GEA) method. The physical and chemical properties of the membranes with different n-HA contents and CS/NaCMC ratios were characterized by Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction and mechanical test. The schematic formation mechanism of the membrane was discussed. The results show that GEA is an effective method to prepare the polyelectrolyte complex (PEC) membrane, in which oppositely charged CS-NaCMC polysaccharides can assemble mildly and gradually through electrostatic interaction to form the membrane framework, while the filled n-HA crystals can regulate the structure stability of the composite membrane. The optimum preparation condition for the PEC membrane can be fixed to a content of 60 wt% n-HA, an equivalent amount of CS to NaCMC and a drying temperature of 60°C. The PEC membrane may have good prospect for guided bone regeneration.

  16. Finding common ground in implementation: towards a theory of gradual commonality.

    Science.gov (United States)

    Ter Haar, Marian; Aarts, Noelle; Verhoeven, Piet

    2016-03-01

    This article reports on an empirical study that aimed to design a practice-based theory about collaboration on the local implementation of a nationally developed health-promoting intervention. The study's objective is to better understand the dynamic process of complex collaboration. The research is based on a Delphi study among some 100 individuals in local and regional networks, in which various professionals work together to implement the BeweegKuur, which translates as 'course of exercise'. The BeweegKuur is a combined lifestyle intervention aimed at promoting sufficient physical exercise and a healthy diet among people in the Netherlands who are overweight and at risk of diabetes. The Delphi study in three rounds systematically and interactively constructs a common perspective on implementation, reflecting stakeholders' ideas about the collaboration and providing an insight into how these ideas are influenced by the context of the implementation. The statistical and qualitative analyses of the responses to the feedback in the Delphi study form the basis for this practice-based theory on complex collaboration, called the theory of gradual commonality. During interaction, consensus gradually emerges about co-creation as a collaboration strategy. Co-creation leaves room for various ways of achieving the ambitions of the BeweegKuur. This article discusses the importance of this practice-based theory and the value of the Delphi research strategy for promoting health. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. Study on FPGA-Based Emulator for the Diagnosis of Gradual Degradation in Reciprocating Pump

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Sang Sun; Kim, Wooshik [Sejong Univ., Seoul (Korea, Republic of); Kim, Tae Yun; Chai, Jang Bom [Ajou Univ., Suwon (Korea, Republic of)

    2017-01-15

    The purpose of this study is to develop a method for diagnosing the degree of gradual degradation of a reciprocating pump caused by continuous use as a water supply pump in a nuclear power plant. Normally, the progress of such degradation is too slow to be noticed. Hence, it is difficult to determine the degree of degradation using the existing diagnostic methods. In this paper, we propose a new method by which the normal state and the degraded state of the pump can be differentiated, so that the degree of degradation can be identified. First, an emulator was developed using FPGA by providing the parameters of the pump under normal state, so that the emulator generates the information of the pump in the healthy state. Then, by comparing this information with the parameters received from various output sensors of the emulator during the current state, it is possible to identify and measure the degree of gradual degradation. This paper presents some of the results obtained during the development process, and results that show how the emulator operates, by comparing the data collected from an actual pump.

  18. The Migration of Cancer Cells in Gradually Varying Chemical Gradients and Mechanical Constraints

    Directory of Open Access Journals (Sweden)

    Smitha M. N. Rao

    2014-01-01

    Full Text Available We report a novel approach to study cell migration under physical stresses by utilizing established growth factor chemotaxis. This was achieved by studying cell migration in response to epidermal growth factor (EGF chemoattraction in a gradually tapered space, imposing mechanical stresses. The device consisted of two 5-mm-diameter chambers connected by ten 600 µm-long and 10 µm-high tapered microchannels. The taper region gradually changes the width of the channel. The channels tapered from 20 µm to 5 µm over a transition length of 50 µm at a distance of 250 µm from one of the chambers. The chemoattractant drove cell migration into the narrow confines of the tapered channels, while the mechanical gradient clearly altered the migration of cells. Cells traversing the channels from the wider to narrow-end and vice versa were observed using time-lapsed imaging. Our results indicated that the impact of physical stress on cell migration patterns may be cell type specific.

  19. Gradual edge enhancement in spiral phase contrast imaging with fractional vortex filters.

    Science.gov (United States)

    Wang, Jikang; Zhang, Wuhong; Qi, Qianqian; Zheng, Shasha; Chen, Lixiang

    2015-10-29

    In the spiral phase contrast imaging, the integer spiral phase plate (SPP) are generally employed to perform the radial Hilbert transform on the object. Here we introduce fractional SPP filters, instead of the integer ones, to investigate the gradual formation of edge enhancement for pure phase objects. Two spatial light modulators are used in our experimental configuration. One is addressed to display the pure phase object of a five-pointed star, while the other serves as a dynamic filter of fractional topological charge Q. Of interest is the observation of the complete reversal of the edge and background brightness by gradually changing the fractional vortices from Q = 0 to 1. The experimental results were well interpreted based on the OAM spectra of fractional SPP, which indicates that the filtered output image can be considered as a coherent superposition of all possible images that are individually resulted from the integer OAM filtering. Besides, we show that the spiral phase contrast effect can still be observed in real time for a rotating three-leaf clover. Our results may find potential applications in the optical microscopic imaging.

  20. Electron–Ion Intensity Dropouts in Gradual Solar Energetic Particle Events during Solar Cycle 23

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Lun C., E-mail: ltan@umd.edu [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States)

    2017-09-01

    Since the field-line mixing model of Giacalone et al. suggests that ion dropouts cannot happen in the “gradual” solar energetic particle (SEP) event because of the large size of the particle source region in the event, the observational evidence of ion dropouts in the gradual SEP event should challenge the model. We have searched for the presence of ion dropouts in the gradual SEP event during solar cycle 23. From 10 SEP events the synchronized occurrence of ion and electron dropouts is identified in 12 periods. Our main observational facts, including the mean width of electron–ion dropout periods being consistent with the solar wind correlation scale, during the dropout period the dominance of the slab turbulence component and the enhanced turbulence power parallel to the mean magnetic field, and the ion gyroradius dependence of the edge steepness in dropout periods, are all in support of the solar wind turbulence origin of dropout events. Also, our observation indicates that a wide longitude distribution of SEP events could be due to the increase of slab turbulence fraction with the increased longitude distance from the flare-associated active region.

  1. Stochastic seismic inversion based on an improved local gradual deformation method

    Science.gov (United States)

    Yang, Xiuwei; Zhu, Peimin

    2017-12-01

    A new stochastic seismic inversion method based on the local gradual deformation method is proposed, which can incorporate seismic data, well data, geology and their spatial correlations into the inversion process. Geological information, such as sedimentary facies and structures, could provide significant a priori information to constrain an inversion and arrive at reasonable solutions. The local a priori conditional cumulative distributions at each node of model to be inverted are first established by indicator cokriging, which integrates well data as hard data and geological information as soft data. Probability field simulation is used to simulate different realizations consistent with the spatial correlations and local conditional cumulative distributions. The corresponding probability field is generated by the fast Fourier transform moving average method. Then, optimization is performed to match the seismic data via an improved local gradual deformation method. Two improved strategies are proposed to be suitable for seismic inversion. The first strategy is that we select and update local areas of bad fitting between synthetic seismic data and real seismic data. The second one is that we divide each seismic trace into several parts and obtain the optimal parameters for each part individually. The applications to a synthetic example and a real case study demonstrate that our approach can effectively find fine-scale acoustic impedance models and provide uncertainty estimations.

  2. Relationship between solitary pulmonary nodule lung cancer and CT image features based on gradual clustering

    Science.gov (United States)

    Zhang, Weipeng

    2017-06-01

    The relationship between the medical characteristics of lung cancers and computer tomography (CT) images are explored so as to improve the early diagnosis rate of lung cancers. This research collected CT images of patients with solitary pulmonary nodule lung cancer, and used gradual clustering methodology to classify them. Preliminary classifications were made, followed by continuous modification and iteration to determine the optimal condensation point, until iteration stability was achieved. Reasonable classification results were obtained. the clustering results fell into 3 categories. The first type of patients was mostly female, with ages between 50 and 65 years. CT images of solitary pulmonary nodule lung cancer for this group contain complete lobulation and burr, with pleural indentation; The second type of patients was mostly male with ages between 50 and 80 years. CT images of solitary pulmonary nodule lung cancer for this group contain complete lobulation and burr, but with no pleural indentation; The third type of patients was also mostly male with ages between 50 and 80 years. CT images for this group showed no abnormalities. the application of gradual clustering methodology can scientifically classify CT image features of patients with lung cancer in the initial lesion stage. These findings provide the basis for early detection and treatment of malignant lesions in patients with lung cancer.

  3. Health effects of living in the vicinity of the landfills

    Directory of Open Access Journals (Sweden)

    Katarzyna Lar

    2013-12-01

    Full Text Available Landfill sites are the easiest, the cheapest and the most common way of waste management and disposal. In the face of the increasing amount of waste, the dynamics of globalization and urbanization process, waste management is an important issue of ecological policy in highly developed countries. Landfill sites intensify environmental threats for the neighborhood and give rise to toxic substances which impair human health being released from the landfills. These are persistent organic pollutants (POPs, heavy metals and also biological gas, bioaerosols, bacteria and viruses. Scientists have conducted a lot of research to evaluate the impact of landfill sites on human health living in their vicinity. They found increased occurrence of congenital anomalies, increased risk of certain cancers and low birth weight of infants. The results of the studies didn’t deliver absolute proof of relation between the impact of landfill sites on the induction of cancer and other diseases. There is a necessity to conduct further research to evaluate the impact of landfill sites on people health living in the vicinity

  4. Energetic particle fluxes in vicinity of Jupiter's moon Europa

    Science.gov (United States)

    Podzolko, Mikhail; Getselev, Igor; Gubar, Yuriy; Veselovsky, Igor

    Currently several projects of sending research space vehicles to Jupiter and its Galilean moons in 2020 are being developed. In particular, Russian Space Agency proposed the project of Europa lander. During the mission the spacecraft will be affected by charged particles of various origins. The greatest hazard will originate from powerful Jupiter's radiation belts, especially during the time of spacecraft operation near Europa and on its surface. The absorbed radiation dose during 2 months in Europa's orbit under shielding compared to that for "Galileo" spacecraft will amount to almost 1 megarad, the major contribution to it will originate from relativistic electrons. However, near Europa part of the charged particle flux will be shaded by the moon. Obviously, fluxes of particles of all energies on its surface will be lower by at least 2 times, than in the same point of space without Europa. But furthermore, the reduction of the fluxes in vicinity of Europa is nonuniform, and differs for the surface and the low-altitude orbit. This is caused by several factors: the complexity of particle trajectories near Europa and in Jupiter's magnetosphere in general, difference of Europa's orbital plane from Jupiter's geomagnetic equator plane, certain disturbance of Jupiter's magnetic field in vicinity of Europa, possible influence of electric fields and Europa's tenuous atmosphere. In the current study computations of energetic particle flux distribution near Europa and on its surface are made, taking into account several of the above-mentioned factors.

  5. Fasting versus gradual initiation of the ketogenic diet: a prospective, randomized clinical trial of efficacy.

    Science.gov (United States)

    Bergqvist, A G Christina; Schall, Joan I; Gallagher, Paul R; Cnaan, Avital; Stallings, Virginia A

    2005-11-01

    The ketogenic diet (KD) is a 90% fat diet that is an effective treatment for intractable epilepsy. Rapid initiation of the KD requires hospital admission because of the complexity of the protocol and frequent mild and moderate adverse events. The purpose of the study was to compare the efficacy of a gradual KD initiation with the standard KD initiation preceded by a 24- to 48-h fast. Children ages 1 to 14 years with intractable epilepsy were randomized to a fasting initiation (FAST-KD) or gradual initiation (GRAD-KD). Baseline seizure activity was recorded daily for 28 days before admission and continued for the 3-month duration of the study. Effectiveness was measured in two ways: (a) the proportion of subjects with >50% reduction in target seizure type from baseline to 3-month evaluation, and (b) percentage reduction in the frequency of the target seizure type from baseline to 3-month evaluation. Blood glucose was assessed q4 to 6h, and weights, electrolytes, hydration status, vomiting, acid balance, need for interventions (citric acid and sodium citrates (Bicitra) and IV fluids) were assessed daily. Fisher's exact tests were used to examine the association between protocol and occurrence of adverse events, and longitudinal mixed-effects models were used to look for trends in tolerability data over time. Forty-eight subjects, 24 in each arm, were randomized. In the FAST-KD protocol, 58% of the children had >50% reduction in the target seizure type at 3 months, and 21% were seizure free. In the GRAD-KD protocol, 67% had a >50% reduction at 3 months, and 21% were seizure free. The two protocols were equivalent in efficacy (p = 0.033). At 3 months, the FAST-KD median percentage seizure reduction rate was 78% (ranging from 100% reduction to 73% increase in seizures per week) and was 94% (ranging from 100% reduction to 161% increase in seizures per week) for the GRAD-KD protocol. By using a logarithmic transformed percentage reduction rate and an equivalence limit

  6. Experimental and numerical investigation of the flow field in the gradual transition of rectangular to trapezoidal open channels

    Directory of Open Access Journals (Sweden)

    Adel Asnaashari

    2016-01-01

    Full Text Available Transitions are structures that can change geometry and flow velocity through varying the cross-sections of their channels. Under subcritical flow and steady flow conditions, it is necessary to reduce the flow velocity gradually due to increasing water pressure and adverse pressure gradients. Due to the separation of flow and subsequent eddy formation, a significant energy loss is incurred along the transition. This study presents the results of experimental investigations of the subcritical flow along the expansive transition of rectangular to trapezoidal channels. A numerical simulation was developed using a finite volume of fluid (VOF method with a Reynolds stress turbulence model. Water surface profiles and velocity distributions of flow through the transition were measured experimentally and compared with the numerical results. A good agreement between the experimental and numerical model results showed that the Reynolds model and VOF method are capable of simulating the hydraulic flow in open channel transitions. Also, the efficiency of the transition and coefficient of energy head loss were calculated. The results show that with an increasing upstream Froude number, the efficiency of the transition and coefficient of energy head loss decrease and increase, respectively. The results also show the ability of numerical simulation to simulate the flow separation zones and secondary current along the transition for different inlet discharges.

  7. The learning of sciences: a gradual change in the way of learning. The case of vision

    Directory of Open Access Journals (Sweden)

    Bettina M. Bravo

    2009-11-01

    Full Text Available Learning the scientific way of knowledge implies a change in the most implicit principles that guide comprehension, interpretation and explanation of scientific phenomena as well as a change in the type of associated reasoning. With the aim of favouring this type of learning, a teaching programme was developed in relation to vision and implemented with a group of secondary school students. The way of learning of these students was observed at different teaching stages. Findings suggest that during the learning process the way students learn seems to change gradually and that students construct “intermediate” models (right but incomplete that become the basis for the construction of a systemic model proposed by school science.

  8. Gradual caldera collapse at Bárdarbunga volcano, Iceland, regulated by lateral magma outflow.

    Science.gov (United States)

    Gudmundsson, Magnús T; Jónsdóttir, Kristín; Hooper, Andrew; Holohan, Eoghan P; Halldórsson, Sæmundur A; Ófeigsson, Benedikt G; Cesca, Simone; Vogfjörd, Kristín S; Sigmundsson, Freysteinn; Högnadóttir, Thórdís; Einarsson, Páll; Sigmarsson, Olgeir; Jarosch, Alexander H; Jónasson, Kristján; Magnússon, Eyjólfur; Hreinsdóttir, Sigrún; Bagnardi, Marco; Parks, Michelle M; Hjörleifsdóttir, Vala; Pálsson, Finnur; Walter, Thomas R; Schöpfer, Martin P J; Heimann, Sebastian; Reynolds, Hannah I; Dumont, Stéphanie; Bali, Eniko; Gudfinnsson, Gudmundur H; Dahm, Torsten; Roberts, Matthew J; Hensch, Martin; Belart, Joaquín M C; Spaans, Karsten; Jakobsson, Sigurdur; Gudmundsson, Gunnar B; Fridriksdóttir, Hildur M; Drouin, Vincent; Dürig, Tobias; Aðalgeirsdóttir, Guðfinna; Riishuus, Morten S; Pedersen, Gro B M; van Boeckel, Tayo; Oddsson, Björn; Pfeffer, Melissa A; Barsotti, Sara; Bergsson, Baldur; Donovan, Amy; Burton, Mike R; Aiuppa, Alessandro

    2016-07-15

    Large volcanic eruptions on Earth commonly occur with a collapse of the roof of a crustal magma reservoir, forming a caldera. Only a few such collapses occur per century, and the lack of detailed observations has obscured insight into the mechanical interplay between collapse and eruption. We use multiparameter geophysical and geochemical data to show that the 110-square-kilometer and 65-meter-deep collapse of Bárdarbunga caldera in 2014-2015 was initiated through withdrawal of magma, and lateral migration through a 48-kilometers-long dike, from a 12-kilometers deep reservoir. Interaction between the pressure exerted by the subsiding reservoir roof and the physical properties of the subsurface flow path explain the gradual, near-exponential decline of both collapse rate and the intensity of the 180-day-long eruption. Copyright © 2016, American Association for the Advancement of Science.

  9. Finite element analysis of gradually and rapidly varied unsteady flow in open channel : II. Applications

    Energy Technology Data Exchange (ETDEWEB)

    Han, Kun Yeun; Park, Jae Hong; Lee, Eul Rae [Kyungpook National University, Taegu (Korea, Republic of)

    1997-02-28

    Petrov-Galerkin finite element model for analyzing dynamic wave equation is applied to gradually and rapidly varied unsteady flow. The model is verified by applying to hydraulic jump, nonlinear disturbance propagation in frictionless horizontal channel and dam-break analysis. It shows stable and accurate results compared with analytical solutions for various cases. The model is applied to a surge propagation in a frictionless horizontal channel. Three-dimensional water surface profiles show that the computed result converges to the analytical one with sharp discontinuity. The model is also applied to the Taehwa River to analyze unsteady flood wave propagation. The computed results have good agreements with those of DWOPER model in terms of discharge and stage hydrographs. (author). 19 refs., 22 figs.

  10. Surface models and gradually peeled volume model to explore hand structures.

    Science.gov (United States)

    Chung, Beom Sun; Kwon, Koojoo; Shin, Byeong-Seok; Chung, Min Suk

    2017-05-01

    This study was intended to confirm whether simultaneous examination of surface and volume models contributes to learning of hand structures. Outlines of the skin, muscles, and bones of the right hand were traced in sectioned images of a male cadaver to create surface models of the structures. After the outlines were filled with selected colors, the color-filled sectioned images were stacked to produce a volume model of the hand, from which the skin was gradually peeled. The surface models provided locational orientation of the hand structures such as extrinsic and intrinsic hand muscles, while the peeled volume model revealed the depth of the individual hand structures. In addition, the characteristic appearances of the radial artery and the wrist joint were confirmed. The exploration of the volume model accompanied by equivalent surface models is synergistically helpful for understanding the morphological properties of hand structures. Copyright © 2017 Elsevier GmbH. All rights reserved.

  11. Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation.

    Science.gov (United States)

    Chow, Brian Wai; Gu, Chenghua

    2017-03-22

    Blood-central nervous system (CNS) barriers partition neural tissues from the blood, providing a homeostatic environment for proper neural function. The endothelial cells that form blood-CNS barriers have specialized tight junctions and low rates of transcytosis to limit the flux of substances between blood and CNS. However, the relative contributions of these properties to CNS barrier permeability are unknown. Here, by studying functional blood-retinal barrier (BRB) formation in mice, we found that immature vessel leakage occurs entirely through transcytosis, as specialized tight junctions are functional as early as vessel entry into the CNS. A functional barrier forms only when transcytosis is gradually suppressed during development. Mutant mice with elevated or reduced levels of transcytosis have delayed or precocious sealing of the BRB, respectively. Therefore, the temporal regulation of transcytosis governs the development of a functional BRB, and suppression of transcytosis is a principal contributor for functional barrier formation. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Assessing the economic feasibility of the gradual decarbonization of a large electric power system

    DEFF Research Database (Denmark)

    Santos-Alamillos, Francisco; Archer, Cristina; Noel, Lance Douglas

    2017-01-01

    The decarbonization of power systems is among the primary actions to fight air pollution and climate change. In this study, we evaluate the costs of a gradual transition towards a new power system in which the oldest coal plants are replaced with low-carbon power plants. We developed the Wind...... of coal. Different strategies to replace coal plants are evaluated: 1) installing only new, high-efficiency, natural-gas combined-cycle plants (control case), 2) installing new wind farms in combination with natural-gas combined-cycle plants used as spinning reserves (wind case), and 3) same as the wind...... of new natural-gas reserve capacity, is the most economic and the most environmentally responsible pathway to replace retiring coal-fired power plants in PJM....

  13. Gradual onset and recovery of the Younger Dryas abrupt climate event in the tropics.

    Science.gov (United States)

    Partin, J W; Quinn, T M; Shen, C-C; Okumura, Y; Cardenas, M B; Siringan, F P; Banner, J L; Lin, K; Hu, H-M; Taylor, F W

    2015-09-02

    Proxy records of temperature from the Atlantic clearly show that the Younger Dryas was an abrupt climate change event during the last deglaciation, but records of hydroclimate are underutilized in defining the event. Here we combine a new hydroclimate record from Palawan, Philippines, in the tropical Pacific, with previously published records to highlight a difference between hydroclimate and temperature responses to the Younger Dryas. Although the onset and termination are synchronous across the records, tropical hydroclimate changes are more gradual (>100 years) than the abrupt (10-100 years) temperature changes in the northern Atlantic Ocean. The abrupt recovery of Greenland temperatures likely reflects changes in regional sea ice extent. Proxy data and transient climate model simulations support the hypothesis that freshwater forced a reduction in the Atlantic meridional overturning circulation, thereby causing the Younger Dryas. However, changes in ocean overturning may not produce the same effects globally as in Greenland.

  14. Compensatory smoking from gradual and immediate reduction in cigarette nicotine content.

    Science.gov (United States)

    Hatsukami, Dorothy K; Donny, Eric C; Koopmeiners, Joseph S; Benowitz, Neal L

    2015-02-01

    Reducing the addictiveness of cigarettes by reducing their nicotine content can potentially have a profound impact on public health. Two different approaches to nicotine reduction have been proposed: gradual and immediate. To determine if either of these approaches results in significant compensatory smoking behavior, which might lead to safety concerns, we performed a secondary analysis of data from studies that have utilized these two approaches. The number of cigarettes smoked per day, carbon monoxide exposure, and cotinine levels in plasma or urine were assessed while participants smoked reduced nicotine content cigarettes and compared with when they smoked their usual brand cigarettes. The results showed that in general, these two approaches led to minimal compensatory smoking and reduced levels of cotinine over the course of the experimental period, suggesting that neither of these approaches poses a major safety concern. ©2014 American Association for Cancer Research.

  15. Gradually varied flow in compound open channels; Flujo gradualmente variado en canales de seccion compuesta

    Energy Technology Data Exchange (ETDEWEB)

    Sotela Avila, Gilberto [Universidad Nacional Autonoma de Mexico (Mexico)

    2001-03-01

    The author shows that the computation of gradually-varied-flow profiles in prismatic compound channels involves the solution of the dynamic equation, but using the compound channel Froude number defined by Blalock and Sturm. The same equation is used for non-prismatic channels by dividing the channel into short reaches and carrying the computation step by step through an iterative process. [Spanish] El autor demuestra que los perfiles del flujo gradualmente variado en canales prismaticos de seccion compuesta se pueden determinar mediante la integracion de la llamada ecuacion dinamica, pero usando el numero de Froude definido por Blalock y Sturm para este tipo de canales. Cuando no son prismaticos, tambien se aplica la ecuacion de la energia por tramos y el calculo sigue un proceso iterativo una vez definidos los tirantes criticos multiples y la zona en que se desarrolla el perfil.

  16. Assessing the economic feasibility of the gradual decarbonization of a large electric power system

    DEFF Research Database (Denmark)

    Santos-Alamillos, Francisco; Archer, Cristina; Noel, Lance Douglas

    2017-01-01

    The decarbonization of power systems is among the primary actions to fight air pollution and climate change. In this study, we evaluate the costs of a gradual transition towards a new power system in which the oldest coal plants are replaced with low-carbon power plants. We developed the Wind...... Energy Integration Cost Advisor Model (WEICAM) to analyze different strategies for this energy transition and determine the most cost-effective roadmap, with and without externalities. The test case is the PJM Interconnection, one of the power systems in the United States with the largest fraction...... decommissioned and an increase in the levelized cost of electricity from 49.1 to 53.6 $/MWh (without externalities). In addition, selecting the windiest sites – even far away from the PJM region – is cheaper than selecting local but less windy sites. When externalities due to human health and environmental...

  17. Space-time variability of floods across Germany: Gradual trends, step changes and fluctuations

    Science.gov (United States)

    Merz, Bruno; Vorogushyn, Sergiy; Viet Dung, Nguyen; Schröter, Kai

    2015-04-01

    The space-time variability of flood magnitude and frequency across Germany at the interannual and decadal time scale is analyzed and interpreted. The analyses are based on flood time series of 68 catchments for a joint period of 74 years. The catchments are distributed across Germany and show different flood regimes. Different statistical tests are applied to investigate different types of flood changes: gradual trends, step changes and fluctuations. In addition, changes in the mean behavior and in the variability are studied. A focus is placed on the spatial stability of changes, i.e. answering the question to which extent flood changes are coherent across Germany. The joint analysis of changes for a large number of catchments allows interpreting the causes of the observed changes. For instance, climate-related flood changes are expected to show a different behavior than changes caused by river training or land-use change.

  18. An evolutionary perspective on gradual formation of superego in the primal horde.

    Science.gov (United States)

    Pulcu, Erdem

    2014-01-01

    Freud proposed that the processes which occurred in the primal horde are essential for understanding superego formation and therefore, the successful dissolution of the Oedipus complex. However, Freud theorized superego formation in the primal horde as if it is an instant, all-or-none achievement. The present paper proposes an alternative model aiming to explain gradual development of superego in the primitive man. The proposed model is built on knowledge from evolutionary and neural sciences as well as anthropology, and it particularly focuses on the evolutionary significance of the acquisition of fire by hominids in the Pleistocene period in the light of up-to-date archaeological findings. Acquisition of fire is discussed as a form of sublimation which might have helped Prehistoric man to maximize the utility of limited evolutionary biological resources, potentially contributing to the rate and extent of bodily evolution. The limitations of both Freud's original conceptualization and the present model are discussed accordingly in an interdisciplinary framework.

  19. SPECTRAL PROPERTIES OF LARGE GRADUAL SOLAR ENERGETIC PARTICLE EVENTS. I. FE, O, AND SEED MATERIAL

    Energy Technology Data Exchange (ETDEWEB)

    Desai, M. I.; Dayeh, M. A.; Ebert, R. W.; Mccomas, D. J.; Schwadron, N. A. [Southwest Research Institute, 6220 Culebra Road, San Antonio, TX 78238 (United States); Mason, G. M. [Johns Hopkins University/Applied Physics Laboratory, Laurel, MD 20723 (United States); Li, G. [CSPAR, University of Alabama in Huntsville, Huntsville, AL 35756 (United States); Cohen, C. M. S.; Mewaldt, R. A. [California Institute of Technology, Pasadena, CA 91125 (United States); Smith, C. W., E-mail: mdesai@swri.edu [Department of Physics and Space Science Center, University of New Hampshire, Durham, NH 03824 (United States)

    2016-01-10

    We have surveyed ∼0.1–100 MeV nucleon{sup −1} O and Fe fluence spectra during 46 isolated, large gradual SEP events observed at ACE during solar cycles 23 and 24. Most SEP spectra are well represented by the four-parameter Band function with a normalization constant, low-energy spectral slope, high-energy spectral slope, and break energy. The O and Fe spectral slopes are similar and most spectra steepen above the break energy, probably due to common acceleration and transport processes affecting different ion species. SEP spectra above the break energies depend on the origin of the seed population; larger contributions of suprathermal flare material result in higher Fe/O ratios and flatter spectra at higher energies. SEP events with steeper O spectra at low energies and higher break energies are associated with slower coronal mass ejections (CMEs), while those associated with fast (>2000 km s{sup −1}) CMEs and ground level enhancements have harder or flatter spectra at low and high energies, and O break energies between ∼1 and 10 MeV nucleon{sup −1}. The latter events are enriched in {sup 3}He and higher-energy Fe, and have Fe spectra that rollover at significantly lower energies compared with O, probably because Fe ions with smaller Q/M ratios can escape from the distant shock more easily than O ions with larger Q/M ratios. We conclude that SEP spectral properties result from many complex and competing effects, namely Q/M-dependent scattering, shock properties, and the origin of the seed populations, all of which must be taken into account to develop a comprehensive picture of CME-driven shock acceleration of large gradual SEP events.

  20. Swarm of bees and particles algorithms in the problem of gradual failure reliability assurance

    Directory of Open Access Journals (Sweden)

    M. F. Anop

    2015-01-01

    Full Text Available Probability-statistical framework of reliability theory uses models based on the chance failures analysis. These models are not functional and do not reflect relation of reliability characteristics to the object performance. At the same time, a significant part of the technical systems failures are gradual failures caused by degradation of the internal parameters of the system under the influence of various external factors.The paper shows how to provide the required level of reliability at the design stage using a functional model of a technical object. Paper describes the method for solving this problem under incomplete initial information, when there is no information about the patterns of technological deviations and degradation parameters, and the considered system model is a \\black box" one.To this end, we formulate the problem of optimal parametric synthesis. It lies in the choice of the nominal values of the system parameters to satisfy the requirements for its operation and take into account the unavoidable deviations of the parameters from their design values during operation. As an optimization criterion in this case we propose to use a deterministic geometric criterion \\reliability reserve", which is the minimum distance measured along the coordinate directions from the nominal parameter value to the acceptability region boundary rather than statistical values.The paper presents the results of the application of heuristic swarm intelligence methods to solve the formulated optimization problem. Efficiency of particle swarm algorithms and swarm of bees one compared with undirected random search algorithm in solving a number of test optimal parametric synthesis problems in three areas: reliability, convergence rate and operating time. The study suggests that the use of a swarm of bees method for solving the problem of the technical systems gradual failure reliability ensuring is preferred because of the greater flexibility of the

  1. Melatonin in the afternoons of a gradually advancing sleep schedule enhances the circadian rhythm phase advance.

    Science.gov (United States)

    Crowley, Stephanie J; Eastman, Charmane I

    2013-02-01

    We test methods to advance (shift earlier) circadian rhythms without producing misalignment between rhythms and sleep. We previously tested (1) a gradually advancing sleep/dark schedule plus morning bright light and afternoon/evening melatonin and (2) the same sleep schedule with only morning bright light. Now we report on the same sleep schedule with only afternoon/evening melatonin. This study aims to examine phase advances, sleepiness, and performance in response to melatonin compared to placebo. Twelve adults (five female individuals) aged 20-45 years (mean ± SD = 28.3 ± 7.3 years) completed this within-subjects placebo-controlled counterbalanced study. The participants slept on fixed 8-h sleep schedules for nine days. Then, sleep/dark was advanced by 1 h/day for three consecutive days of treatment. The participants took 3 mg of melatonin or placebo 11 h before baseline sleep midpoint (the optimal time to produce phase advances) on the first treatment day and 1 h earlier on each subsequent day. We measured the dim light melatonin onset before and after treatment. The participants rated subjective symptoms throughout the study. They completed the Psychomotor Vigilance Task and rated sleepiness from 1 h before pill ingestion until bedtime on each treatment day. Melatonin produced significantly larger advances (1.3 ± 0.7 h) compared to placebo (0.7 ± 0.7 h); however, in the hours between melatonin ingestion and bed, melatonin caused sleepiness and performance decrements. Adding afternoon/evening melatonin to the gradually advancing sleep schedule increased the phase advance, but given the side effects, like sleepiness, it is better to use morning bright light and perhaps a lower dose of melatonin.

  2. OPTIMAL practice conditions enhance the benefits of gradually increasing error opportunities on retention of a stepping sequence task.

    Science.gov (United States)

    Levac, Danielle; Driscoll, Kate; Galvez, Jessica; Mercado, Kathleen; O'Neil, Lindsey

    2017-12-01

    Physical therapists should implement practice conditions that promote motor skill learning after neurological injury. Errorful and errorless practice conditions are effective for different populations and tasks. Errorful learning provides opportunities for learners to make task-relevant choices. Enhancing learner autonomy through choice opportunities is a key component of the Optimizing Performance through Intrinsic Motivation and Attention for Learning (OPTIMAL) theory of motor learning. The objective of this study was to evaluate the interaction between error opportunity frequency and OPTIMAL (autonomy-supportive) practice conditions during stepping sequence acquisition in a virtual environment. Forty healthy young adults were randomized to autonomy-supportive or autonomy-controlling practice conditions, which differed in instructional language, focus of attention (external vs internal) and positive versus negative nature of verbal and visual feedback. All participants practiced 40 trials of 4, six-step stepping sequences in a random order. Each of the 4 sequences offered different amounts of choice opportunities about the next step via visual cue presentation (4 choices; 1 choice; gradually increasing [1-2-3-4] choices, and gradually decreasing [4-3-2-1] choices). Motivation and engagement were measured by the Intrinsic Motivation Inventory (IMI) and the User Engagement Scale (UES). Participants returned 1-3 days later for retention tests, where learning was measured by time to complete each sequence. No choice cues were offered on retention. Participants in the autonomy-supportive group outperformed the autonomy-controlling group at retention on all sequences (mean difference 2.88s, p autonomy-supportive group performed best at retention on the increasing choice (1-2-3-4) sequence (p autonomy-supportive group reported significantly higher overall motivation (p = .007, t(38) = 0.728, d = 0.248) on the IMI as compared to the autonomy

  3. Decreasing relative risk premium

    DEFF Research Database (Denmark)

    Hansen, Frank

    2007-01-01

    such that the corresponding relative risk premium is a decreasing function of present wealth, and we determine the set of associated utility functions. We find a new characterization of risk vulnerability and determine a large set of utility functions, closed under summation and composition, which are both risk vulnerable...... and have decreasing relative risk premium. We finally introduce the notion of partial risk neutral preferences on binary lotteries and show that partial risk neutrality is equivalent to preferences with decreasing relative risk premium...

  4. Altered expression of sodium channel distribution in the dorsal root ganglion after gradual elongation of rat sciatic nerves.

    Science.gov (United States)

    Ohno, Katsunori; Yokota, Atsushi; Hirofuji, Shinji; Kanbara, Kiyoto; Ohtsuka, Hisashi; Kinoshita, Mitsuo

    2010-04-01

    To elucidate the pathophysiological mechanisms underlying chronic nerve-stretch injury, we gradually lengthened rat femurs by 15 mm at the rate of 0.5 mm/day (group L, n = 13). The control groups comprised sham-operated (group S, n = 10) and naive (group N, n = 8) rats. Immediately after the lengthening, we performed a conduction study on their sciatic nerves and harvested samples. Electrophysiological and histological analyses showed mild conduction slowing and axonal degeneration of unmyelinated fibers in group L rats. Altered mRNA expression of the voltage-gated sodium channels in the dorsal root ganglion was also observed. Tetrodotoxin-resistant (TTX-R) sodium-channel Nav1.8 mRNA expression was significantly decreased and TTX-R sodium-channel Nav1.9 mRNA expression showed a tendency to decrease when compared with the mRNA expressions in the control groups. However, tetrodotoxin-sensitive (TTX-S) sodium-channel Nav1.3 mRNA expression remained unaltered. The immunohistochemical alteration of Nav1.8 protein expression was parallel to the results of the mRNA expression. Previous studies involving neuropathic states have suggested that pain/paresthesia is modulated by a subset of sodium channels, including downregulation and/or upregulation of TTX-R and TTX-S sodium channels, respectively. Our findings indicate that Nav1.8 downregulation may be one of the pathophysiological mechanisms involved in limb lengthening-induced neuropathy.

  5. Quantifying Mapping Orbit Performance in the Vicinity of Primitive Bodies

    Science.gov (United States)

    Pavlak, Thomas A.; Broschart, Stephen B.; Lantoine, Gregory

    2015-01-01

    Predicting and quantifying the capability of mapping orbits in the vicinity of primitive bodies is challenging given the complex orbit geometries that exist and the irregular shape of the bodies themselves. This paper employs various quantitative metrics to characterize the performance and relative effectiveness of various types of mapping orbits including terminator, quasi-terminator, hovering, ping pong, and conic-like trajectories. Metrics of interest include surface area coverage, lighting conditions, and the variety of viewing angles achieved. The metrics discussed in this investigation are intended to enable mission designers and project stakeholders to better characterize candidate mapping orbits during preliminary mission formulation activities. The goal of this investigation is to understand the trade space associated with carrying out remote sensing campaigns at small primitive bodies in the context of a robotic space mission. Specifically, this study seeks to understand the surface viewing geometries, ranges, etc. that are available from several commonly proposed mapping orbits architectures

  6. Particle transport in the vicinity of divertor separatrix

    Science.gov (United States)

    Nishimura, Y.; Lyu, J. C.

    2017-10-01

    Guiding center orbit following code in a tokamak edge geometry is developed which connects straight field line coordinate system (away from the separatrix) and Cartesian coordinate system (in the vicinity of the separatrix) smoothly in the equation of motion. In the presence of magnetic stochasticity charged particles in the closed magnetic field line region can be transported to the open field line region and then hit the divertor plates within several toroidal transits. Our preliminary studies suggest finite heat load both on the inner and outer divertor plates. Energy spectrum of particles reaching the plates (which differs from that of the bulk plasma) as function of imposed magnetic stochasticity, is analyzed. This work is supported by Taiwan MOST 104-2112-M-006-019.

  7. Investigation of pitch and angle in the gradual-triangle lenticular lens for point-blank LED fog lamp.

    Science.gov (United States)

    Chen, Hsi-Chao; Yang, Chi-Hao

    2014-05-10

    The effects of different pitch and angle of gradual-triangle lenticular lens for the point-blank LED fog lamp were investigated under the standard of ECE R19. The novel LED fog lamp was assembled from a point-blank LED light source, a parabolic reflector, and a gradual-triangle lenticular lens. Light tracing analysis was used for the design of the gradual-triangle lenticular lens. The pitch, which varied from 1 to 6 mm, and the apex angle, which changed from 5 to 32 deg, were both investigated in regard to the gradual-triangle lenticular lens. The optimum pitch was 5 mm, and the efficiency of the lamp system and lenticular lens could reach 93% and 98.1% by simulation, respectively. The results of experiment had over 94%, which is similar to that of simulation by normalized cross correlation (NCC) for the light intensity.

  8. Decreasing Relative Risk Premium

    DEFF Research Database (Denmark)

    Hansen, Frank

    We consider the risk premium demanded by a decision maker with wealth x in order to be indifferent between obtaining a new level of wealth y1 with certainty, or to participate in a lottery which either results in unchanged present wealth or a level of wealth y2 > y1. We define the relative risk...... premium as the quotient between the risk premium and the increase in wealth y1–x which the decision maker puts on the line by choosing the lottery in place of receiving y1 with certainty. We study preferences such that the relative risk premium is a decreasing function of present wealth, and we determine...... relative risk premium in the small implies decreasing relative risk premium in the large, and decreasing relative risk premium everywhere implies risk aversion. We finally show that preferences with decreasing relative risk premium may be equivalently expressed in terms of certain preferences on risky...

  9. Free surface profiles in river flows: Can standard energy-based gradually-varied flow computations be pursued?

    Science.gov (United States)

    Cantero, Francisco; Castro-Orgaz, Oscar; Garcia-Marín, Amanda; Ayuso, José Luis; Dey, Subhasish

    2015-10-01

    Is the energy equation for gradually-varied flow the best approximation for the free surface profile computations in river flows? Determination of flood inundation in rivers and natural waterways is based on the hydraulic computation of flow profiles. This is usually done using energy-based gradually-varied flow models, like HEC-RAS, that adopts a vertical division method for discharge prediction in compound channel sections. However, this discharge prediction method is not so accurate in the context of advancements over the last three decades. This paper firstly presents a study of the impact of discharge prediction on the gradually-varied flow computations by comparing thirteen different methods for compound channels, where both energy and momentum equations are applied. The discharge, velocity distribution coefficients, specific energy, momentum and flow profiles are determined. After the study of gradually-varied flow predictions, a new theory is developed to produce higher-order energy and momentum equations for rapidly-varied flow in compound channels. These generalized equations enable to describe the flow profiles with more generality than the gradually-varied flow computations. As an outcome, results of gradually-varied flow provide realistic conclusions for computations of flow in compound channels, showing that momentum-based models are in general more accurate; whereas the new theory developed for rapidly-varied flow opens a new research direction, so far not investigated in flows through compound channels.

  10. Charge state distributions of iron in gradual solar energetic particle events

    Science.gov (United States)

    Ostryakov, V. M.; Stovpyuk, M. F.

    1999-11-01

    The energy and charge spectra of Fe ions accelerated in gradual events are calculated numerically. Our results are compared with the available observations. Stripping of Fe ions by thermal electrons and protons during ion acceleration in the solar corona results in the dependence of mean charge \\barq_Fe on energy. We consider the influence of varying plasma parameters (temperature T, number density N, and spectral index of turbulence S) on the charge distribution of iron. Our calculations indicate T~10^6 K and N~(0.5-1)x10^10 cm^-3 at the accelerating site, provided the characteristic acceleration time is about 1 s. The calculated charge spectra for S>2 and S<2 turn out to be different, but some theoretical and experimental uncertainties do not yet allow this parameter to be extracted from observational data. The theoretically obtained charge distributions of Fe could be important in the light of ACE spacecraft data which are currently available for analysis.

  11. Research on Social Stability Mechanisms Based on Activation Energy and Gradual Activation Reaction Theory

    Science.gov (United States)

    Ning, Miao; Gu, Jifa

    This paper draws a comparison between social stability and chemical reaction process, and brings forward the concept of “social temperature” and “activation energy of social agent”. It is considered that social temperature turns out to be the macro symptom of social average energy, and its unceasing up-climbing roots in the energy accumulation of “inferiorization” process of social system; that “activation energy of social agent” stands for the social energy or temperature where individuals or groups reach the limit of their psychological bearing ability. This paper, basing on above concepts, elaborates on and demonstrates the gradual activation reaction mechanisms of social stability by a lot of concrete examples. It is thought that there is a threshold value for social stability, and the society will be unstable if social temperature goes higher than this value; that the larger the social average activation energy is, the higher the temperature threshold value of social stability will be; and considering that different groups have different activation energy, those fragile groups with low activation energy are often the risk source which might pose a threat to social stability.

  12. Method for modeling the gradual physical degradation of a porous material

    Energy Technology Data Exchange (ETDEWEB)

    Flach, Greg [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-09-20

    Cementitious and other engineered porous materials encountered in waste disposals may degrade over time due to one or more mechanisms. Physical degradation may take the form of cracking (fracturing) and/or altered (e.g. increased) porosity, depending on the material and underlying degradation mechanism. In most cases, the hydraulic properties of degrading materials are expected to evolve due to physical changes occurring over roughly the pore to decimeter scale, which is conducive to calculating equivalent or effective material properties. The exact morphology of a degrading material in its end-state may or may not be known. In the latter case, the fully-degraded condition can be assumed to be similar to a more-permeable material in the surrounding environment, such as backfill soil. Then the fully-degraded waste form or barrier material is hydraulically neutral with respect to its surroundings, constituting neither a barrier to nor conduit for moisture flow and solute transport. Unless the degradation mechanism is abrupt, a gradual transition between the intact initial and fully-degraded final states is desired. Linear interpolation through time is one method for smoothly blending hydraulic properties between those of an intact matrix and those of a soil or other surrogate for the end-state.

  13. Modeling and the Gradual Release of Responsibility: What Does It Look Like in the Classroom?

    Directory of Open Access Journals (Sweden)

    Nancy Maynes

    2010-01-01

    Full Text Available Recent professional development efforts in literacy have highlighted the role of the teacher as a model for students using direct instruction.  Direct instruction is a lesson methodology taught to teacher candidates. We developed a schematic to represent the confluence of evidence found in the research and analysis of several lesson planning templates in order to create a visual representation of the elements of instruction that could be used to plan lessons. Previous research has demonstrated that modeling was not used frequently in classrooms. We were interested in determining if teachers were still using modeling infrequently. To investigate this, we identified three questions we would pursue through action research and mixed methods of analysis in local classrooms. These questions focused on determining the amount of time spent modeling in classrooms and the actions used after modeling to determine the extent these actions were reflected in the research literature. We found that teachers are using modeling much more frequently than was found to be the case in the previous study, but that the instructional actions following modeling are often inconsistent with research literature conceptions.   Key Words: direct instruction, modeling, gradual release of responsibility, models for teaching

  14. Modeling effectiveness of gradual increases in source level to mitigate effects of sonar on marine mammals.

    Science.gov (United States)

    Von Benda-Beckmann, Alexander M; Wensveen, Paul J; Kvadsheim, Petter H; Lam, Frans-Peter A; Miller, Patrick J O; Tyack, Peter L; Ainslie, Michael A

    2014-02-01

    Ramp-up or soft-start procedures (i.e., gradual increase in the source level) are used to mitigate the effect of sonar sound on marine mammals, although no one to date has tested whether ramp-up procedures are effective at reducing the effect of sound on marine mammals. We investigated the effectiveness of ramp-up procedures in reducing the area within which changes in hearing thresholds can occur. We modeled the level of sound killer whales (Orcinus orca) were exposed to from a generic sonar operation preceded by different ramp-up schemes. In our model, ramp-up procedures reduced the risk of killer whales receiving sounds of sufficient intensity to affect their hearing. The effectiveness of the ramp-up procedure depended strongly on the assumed response threshold and differed with ramp-up duration, although extending the duration of the ramp up beyond 5 min did not add much to its predicted mitigating effect. The main factors that limited effectiveness of ramp up in a typical antisubmarine warfare scenario were high source level, rapid moving sonar source, and long silences between consecutive sonar transmissions. Our exposure modeling approach can be used to evaluate and optimize mitigation procedures. © 2013 Society for Conservation Biology.

  15. Sobre a classificação gradual das preposições

    Directory of Open Access Journals (Sweden)

    Lou-Ann Kepla

    2012-11-01

    Full Text Available O presente artigo está ancorado na Neurolinguística de orientação enunciativo-discursiva. A demanda por uma proposta de classificação gradual (em oposição à tradicional classificação categorial das preposições surgiu quando nos propusemos a tarefa de descrever o funcionamento das preposições na fala de sujeitos que apresentam uma linguagem heterogênea. Nestes casos, as classificações correntes das preposições não se mostraram satisfatórias. Os motivos pelos quais preferimos uma classificação que dispõe as preposições numa escala de acordo com os seus graus de gramaticalização serão dispostos depois de feita uma revisão da literatura sobre as classificações das preposições. As classificações propostas por diferentes gramáticos são analisadas juntamente com aquelas adotadas por linguistas preocupados em descrever a linguagem agramática de sujeitos com afasia de produção.

  16. Oxidation mechanism of micron-sized aluminum particles in Al-CO2 gradually heating system

    Science.gov (United States)

    Liu, Y.; Ren, H.; Jiao, Q. J.

    2017-10-01

    Micron-sized aluminum powders were heated in carbon dioxide atmosphere through differential scanning calorimetry (DSC) method in this work. Aluminum powders were oxidized into four distinct stages from room temperature to 1500°C. Stage I, amorphous alumina shell turns to γ-Al2O3 phase from room temperature to 620°C. Stage II, accompany with the aluminum core melting, alumina shell becomes thicker and fragile at the temperature around 667°C which is the melting point of aluminum. Stage III, in the temperature range of 690-1150°C, alumina shell was broken partially because of the inside pressure. Liquid aluminum spurts out through the weak point which becomes cracks on the surface just like volcano eruption and then oxidized by CO2 while the temperature increased from 700°C to 900°C. Stage IV, alumina changes to stable α-Al2O3. From what was presented above, a mechanism of micron-sized aluminum particle oxidation in CO2 under gradually increasing temperature condition was proposed as “eruption model”.

  17. Gradual Diffusion and Punctuated Phase Space Density Enhancements of Highly Relativistic Electrons: Van Allen Probes Observations

    Science.gov (United States)

    Baker, D. N.; Jaynes, A. N.; Li, X.; Henderson, M. G.; Kanekal, S. G.; Reeves, G. D.; Spence, H. E.; Claudepierre, S. G.; Fennell, J. F.; Hudson, M. K.

    2014-01-01

    The dual-spacecraft Van Allen Probes mission has provided a new window into mega electron volt (MeV) particle dynamics in the Earth's radiation belts. Observations (up to E (is) approximately 10MeV) show clearly the behavior of the outer electron radiation belt at different timescales: months-long periods of gradual inward radial diffusive transport and weak loss being punctuated by dramatic flux changes driven by strong solar wind transient events. We present analysis of multi-MeV electron flux and phase space density (PSD) changes during March 2013 in the context of the first year of Van Allen Probes operation. This March period demonstrates the classic signatures both of inward radial diffusive energization and abrupt localized acceleration deep within the outer Van Allen zone (L (is) approximately 4.0 +/- 0.5). This reveals graphically that both 'competing' mechanisms of multi-MeV electron energization are at play in the radiation belts, often acting almost concurrently or at least in rapid succession.

  18. A fault diagnosis system for PV power station based on global partitioned gradually approximation method

    Science.gov (United States)

    Wang, S.; Zhang, X. N.; Gao, D. D.; Liu, H. X.; Ye, J.; Li, L. R.

    2016-08-01

    As the solar photovoltaic (PV) power is applied extensively, more attentions are paid to the maintenance and fault diagnosis of PV power plants. Based on analysis of the structure of PV power station, the global partitioned gradually approximation method is proposed as a fault diagnosis algorithm to determine and locate the fault of PV panels. The PV array is divided into 16x16 blocks and numbered. On the basis of modularly processing of the PV array, the current values of each block are analyzed. The mean current value of each block is used for calculating the fault weigh factor. The fault threshold is defined to determine the fault, and the shade is considered to reduce the probability of misjudgments. A fault diagnosis system is designed and implemented with LabVIEW. And it has some functions including the data realtime display, online check, statistics, real-time prediction and fault diagnosis. Through the data from PV plants, the algorithm is verified. The results show that the fault diagnosis results are accurate, and the system works well. The validity and the possibility of the system are verified by the results as well. The developed system will be benefit for the maintenance and management of large scale PV array.

  19. Water quality in the vicinity of Fenton Hill, 1985 and 1986: Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Purtymun, W.D.; Ferenbaugh, R.W.; Williams, M.C.; Maes, M.N.

    1988-03-01

    Water quality data have been collected since 1974 from established surface and groundwater stations at and in the vicinity of Fenton Hill (Hot Dry Rock Geothermal Demonstration Site) located in the Jemez Mountains. This is part of a continuing program of environmental studies. Data on chemical quality of water were determined for samples collected from 13 surface water and 19 groundwater stations in 1985 and 1986. There were slight variations in the chemical quality of the ground and surface water in 1985 and 1986 as compared with previous analyses; however, these variations are within normal seasonal fluctuations. Chemical uptake in soil, roots, and foliage is monitored in the canyon, which receives intermittent effluent release of water from tests in the geothermal circulation loop and occasional fluids from drilling operations. The chemical concentrations found in soil, roots, and vegetation as the result of effluent release have shown a decrease in concentration down-canyon and also have decreased in concentration with time since the larger releases that took place in the late 1970s and early 1980s. 18 refs., 7 figs., 9 tabs.

  20. 33 CFR 110.190 - Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas, Fla.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas, Fla. 110.190 Section 110.190 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.190 Tortugas Harbor, in vicinity of Garden Key, Dry Tortugas,...

  1. Gradually softening hydrogels for modeling hepatic stellate cell behavior during fibrosis regression.

    Science.gov (United States)

    Caliari, Steven R; Perepelyuk, Maryna; Soulas, Elizabeth M; Lee, Gi Yun; Wells, Rebecca G; Burdick, Jason A

    2016-06-13

    The extracellular matrix (ECM) presents an evolving set of mechanical cues to resident cells. We developed methacrylated hyaluronic acid (MeHA) hydrogels containing both stable and hydrolytically degradable crosslinks to provide cells with a gradually softening (but not fully degradable) milieu, mimicking physiological events such as fibrosis regression. To demonstrate the utility of this cell culture system, we studied the phenotype of rat hepatic stellate cells, the major liver precursors of fibrogenic myofibroblasts, within this softening environment. Stellate cells that were mechanically primed on tissue culture plastic attained a myofibroblast phenotype, which persisted when seeded onto stiff (∼20 kPa) hydrogels. However, mechanically primed stellate cells on stiff-to-soft (∼20 to ∼3 kPa) hydrogels showed reversion of the myofibroblast phenotype over 14 days, with reductions in cell area, expression of the myofibroblast marker alpha-smooth muscle actin (α-SMA), and Yes-associated protein/Transcriptional coactivator with PDZ-binding motif (YAP/TAZ) nuclear localization when compared to stellate cells on stiff hydrogels. Cells on stiff-to-soft hydrogels did not fully revert, however. They displayed reduced expression of glial fibrillary acidic protein (GFAP), and underwent abnormally rapid re-activation to myofibroblasts in response to re-stiffening of the hydrogels through introduction of additional crosslinks. These features are typical of stellate cells with an intermediate phenotype, reported to occur in vivo with fibrosis regression and re-injury. Together, these data suggest that mechanics play an important role in fibrosis regression and that integrating dynamic mechanical cues into model systems helps capture cell behaviors observed in vivo.

  2. Osborne Reynolds pipe flow: Direct simulation from laminar through gradual transition to fully developed turbulence

    Science.gov (United States)

    Wu, Xiaohua; Moin, Parviz; Adrian, Ronald J.; Baltzer, Jon R.

    2015-01-01

    The precise dynamics of breakdown in pipe transition is a century-old unresolved problem in fluid mechanics. We demonstrate that the abruptness and mysteriousness attributed to the Osborne Reynolds pipe transition can be partially resolved with a spatially developing direct simulation that carries weakly but finitely perturbed laminar inflow through gradual rather than abrupt transition arriving at the fully developed turbulent state. Our results with this approach show during transition the energy norms of such inlet perturbations grow exponentially rather than algebraically with axial distance. When inlet disturbance is located in the core region, helical vortex filaments evolve into large-scale reverse hairpin vortices. The interaction of these reverse hairpins among themselves or with the near-wall flow when they descend to the surface from the core produces small-scale hairpin packets, which leads to breakdown. When inlet disturbance is near the wall, certain quasi-spanwise structure is stretched into a Lambda vortex, and develops into a large-scale hairpin vortex. Small-scale hairpin packets emerge near the tip region of the large-scale hairpin vortex, and subsequently grow into a turbulent spot, which is itself a local concentration of small-scale hairpin vortices. This vortex dynamics is broadly analogous to that in the boundary layer bypass transition and in the secondary instability and breakdown stage of natural transition, suggesting the possibility of a partial unification. Under parabolic base flow the friction factor overshoots Moody’s correlation. Plug base flow requires stronger inlet disturbance for transition. Accuracy of the results is demonstrated by comparing with analytical solutions before breakdown, and with fully developed turbulence measurements after the completion of transition. PMID:26080447

  3. Gradual enhancement of ethyl acetate production through promoter engineering in chinese liquor yeast strains.

    Science.gov (United States)

    Dong, Jian; Hong, Kun-Qiang; Hao, Ai-Li; Zhang, Cui-Ying; Fu, Xiao-Meng; Wang, Peng-Fei; Xiao, Dong-Guang

    2018-01-05

    As content and proportion of ethyl acetate is critical to the flavor and quality of beverages, the concise regulation of the ethyl acetate metabolism is a major issue in beverage fermentations. In this study, for ethyl acetate yield regulation, we finely modulated the expression of ATF1 through precise and seamless insertion of serially truncated PGK1 promoter from the 3' end by 100bp steps in the Chinese liquor yeast, CLy12a. The three engineered promoters carrying 100-, 200-, and 300-bp truncations exhibited reduced promoter strength but unaffected growth. These three promoters were integrated into the CLy12a strain, generating strains CLy12a-P-100, CLy12a-P-200, and CLy12a-P-300, respectively. The transcription levels of CLy12a-P-100, CLy12a-P-200, and CLy12a-P-300 were 20%, 17%, and 10% of that of CLy12a-P, respectively. The AATase (alcohol acetyl transferases, encoded by the ATF1 gene) activity of three engineered strains were 36%, 56%, and 62% of that of CLy12a-P. In the liquid fermentation of corn hydrolysate at 30°C, the concentration of ethyl acetate in CLy12a-P-100, CLy12a-P-200, and CLy12a-P-300 were reduced by 28%, 30%, and 42%, respectively, compared to CLy12a-P. These results verifying that the ethyl acetate yield could be gradually enhanced by finely modulating the expression of ATF1. The engineered strain CLy12a-P-200 produced the ethyl acetate concentration with the best sensorial quality compared to the other engineered yeast strains. The method proposed in this work supplies a practical proposal for breeding Chinese liquor yeast strains with finely modulated ethyl acetate yield. © 2018 American Institute of Chemical Engineers Biotechnol. Prog., 2018. © 2018 American Institute of Chemical Engineers.

  4. Osborne Reynolds pipe flow: Direct simulation from laminar through gradual transition to fully developed turbulence.

    Science.gov (United States)

    Wu, Xiaohua; Moin, Parviz; Adrian, Ronald J; Baltzer, Jon R

    2015-06-30

    The precise dynamics of breakdown in pipe transition is a century-old unresolved problem in fluid mechanics. We demonstrate that the abruptness and mysteriousness attributed to the Osborne Reynolds pipe transition can be partially resolved with a spatially developing direct simulation that carries weakly but finitely perturbed laminar inflow through gradual rather than abrupt transition arriving at the fully developed turbulent state. Our results with this approach show during transition the energy norms of such inlet perturbations grow exponentially rather than algebraically with axial distance. When inlet disturbance is located in the core region, helical vortex filaments evolve into large-scale reverse hairpin vortices. The interaction of these reverse hairpins among themselves or with the near-wall flow when they descend to the surface from the core produces small-scale hairpin packets, which leads to breakdown. When inlet disturbance is near the wall, certain quasi-spanwise structure is stretched into a Lambda vortex, and develops into a large-scale hairpin vortex. Small-scale hairpin packets emerge near the tip region of the large-scale hairpin vortex, and subsequently grow into a turbulent spot, which is itself a local concentration of small-scale hairpin vortices. This vortex dynamics is broadly analogous to that in the boundary layer bypass transition and in the secondary instability and breakdown stage of natural transition, suggesting the possibility of a partial unification. Under parabolic base flow the friction factor overshoots Moody's correlation. Plug base flow requires stronger inlet disturbance for transition. Accuracy of the results is demonstrated by comparing with analytical solutions before breakdown, and with fully developed turbulence measurements after the completion of transition.

  5. Decreasing asthma morbidity

    African Journals Online (AJOL)

    1994-12-12

    Dec 12, 1994 ... Apart from the optimal use of drugs, various supplementary methods have been tested to decrease asthma morbidity, usually in patients from reiatively affluent socio-economic backgrounds. A study of additional measures taken in a group of moderate to severe adult asthmatics from very poor socio- ...

  6. Decreasing Serial Cost Sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter

    The increasing serial cost sharing rule of Moulin and Shenker [Econometrica 60 (1992) 1009] and the decreasing serial rule of de Frutos [Journal of Economic Theory 79 (1998) 245] have attracted attention due to their intuitive appeal and striking incentive properties. An axiomatic characterization...

  7. Decreasing serial cost sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter Raahave

    2009-01-01

    The increasing serial cost sharing rule of Moulin and Shenker (Econometrica 60:1009-1037, 1992) and the decreasing serial rule of de Frutos (J Econ Theory 79:245-275, 1998) are known by their intuitive appeal and striking incentive properties. An axiomatic characterization of the increasing serial...

  8. A Study Of Environmental Impacts On The Coral Resources In The Vicinity Of The Saint Martin Island Bangladesh

    Directory of Open Access Journals (Sweden)

    Shaikh Sayed Ahammed

    2015-08-01

    Full Text Available A study of the environmental impacts on the coral resources in the vicinity of the Saint Martin Island Bangladesh was conducted with a view to making an assessment of the current status of coral resources in the island and identifying major natural and anthropogenic environmental threats to the future sustainability of these resources. It is evident that the coral resources have been reduced significantly and currently only 41 coral species are available. The existing environmental condition assessed by pH salinity turbidity and temperature in the island is not found responsible for the survival of the corals. The study also reveals that the major anthropogenic interventions are responsible for the gradual depletion of the coral resources. The major anthropogenic threats to the coral resources are coral collection and overfishing. In addition coral extraction is identified as a potential threat to the future integrity of coral communities in the island. Environmental threats from anthropogenic activities related to sedimentation land erosion and pollution are also the concerns for the coral communities in the island. For the conservation of the coral population no coral monitoring cell has been established in this island.

  9. An estimation of water origins in the vicinity of a tropical cyclone's center and associated dynamic processes

    Science.gov (United States)

    Takakura, Toshinari; Kawamura, Ryuichi; Kawano, Tetsuya; Ichiyanagi, Kimpei; Tanoue, Masahiro; Yoshimura, Kei

    2018-01-01

    To clarify the time evolution of water origins in the vicinity of a tropical cyclone (TC)'s center, we have simulated Typhoon Man-yi (July 2007) in our case study, using an isotopic regional spectral model. The model results confirm that the replacement of water origins occurs successively as the TC develops and migrates northward over the western North Pacific. It is confirmed that, in this case, a significant proportion of total precipitable water around the cyclone center comes from external regions rather than the underlying ocean during the mature stage of a TC. Similar features can also be seen in the proportion of each oceanic origin to total condensation. Indian Ocean, South China Sea, and Maritime Continent water vapors begin to increase gradually at the developing stage and reach their peak at the decay stage when the TC approaches southwestern Japan. These remote ocean vapors are transported to the east of the cyclone via the moisture conveyor belt, a zone characterized by distinct low-level moisture flux that stretches from the Indian Ocean to the TC, and are further supplied into the inner region of the TC by inflow within the boundary layer associated with its secondary circulation. Since it takes time to undergo these two dynamic processes, the delayed influence of remote ocean vapors on the TC appears to become evident during the mature stage.

  10. Change in enzyme production by gradually drying culture substrate during solid-state fermentation.

    Science.gov (United States)

    Ito, Kazunari; Gomi, Katsuya; Kariyama, Masahiro; Miyake, Tsuyoshi

    2015-06-01

    The influence of drying the culture substrate during solid-state fermentation on enzyme production was investigated using a non-airflow box. The drying caused a significant increase in enzyme production, while the mycelium content decreased slightly. This suggests that changes in the water content in the substrate during culture affect enzyme production in fungi. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  11. Enhanced gamma radiation towards the rotation axis from the immediate vicinity of extremely rotating black holes

    Science.gov (United States)

    Song, Yoogeun; Pu, Hung-Yi; Hirotani, Kouichi; Matsushita, Satoki; Kong, Albert K. H.; Chang, Hsiang-Kuang

    2017-10-01

    We investigate the acceleration of electrons and positrons by magnetic-field-aligned electric fields in the polar funnel of an accreting black hole (BH). Applying the pulsar outer-gap theory to BH magnetospheres, we find that such a lepton accelerator arises in the immediate vicinity of the event horizon due to frame-dragging, and that their gamma-ray luminosity increases with decreasing accretion rate. Furthermore, we demonstrate that the gamma-ray flux is enhanced along the rotation axis by more than an order of magnitude if the BH spin increases from a = 0.90M to a = 0.9999M. As a result, if a ten-solar-mass, almost-maximally rotating BH is located within 3 kpc, when its accretion rate is between 0.005 and 0.01 per cent of the Eddington rate, its high-energy flare becomes detectable with the Fermi/Large Area Telescope, provided that the flare lasts longer than 1.2 months and that we view the source nearly along the rotation axis. In addition, its very high energy flux is marginally detectable with the Cherenkov Telescope Array, provided that the flare lasts longer than a night and that our viewing angle is about 45 deg with respect to the rotation axis.

  12. The response of digestive enzyme activity in the mature Chinese mitten crab, Eriocheir sinensis (Decapoda: Brachyura, to gradual increase of salinity

    Directory of Open Access Journals (Sweden)

    Ruifang Wang

    2013-06-01

    Full Text Available Mature Chinese mitten crabs, Eriocheir sinensis, were exposed to brackish water or seawater as an obligatory part of their reproductive migration. Physiological and biochemical reorganization were needed to adapt them to this migration. To understand the digestive adjustments of Eriocheir sinensis at biochemical level during this transformation from freshwater to seawater, the response of the activity of five digestive enzymes (amylase, cellulase, pepsin, trypsin and lipase in the hepatopancreas to salinities increasing gradually from 0 (freshwater to 35 (seawater was analysed in mature females and males. Digestive enzymes exhibited significantly higher activities in the hepatopancreas of males than those of females, except lipase. In females, amylase, pepsin and trypsin activities began to decrease significantly as the salinity reached 28, and cellulase activity decreased at 35; in males, a considerable decrease in the activity of digestive enzymes, except lipase, was observed at 21 and higher salinities, while an increase was observed at 14. Reduced enzyme activities at elevated salinities suggest that the digestive capacity of crabs for diets becomes weak, and all these digestive enzymes participated in digestive adjustments during osmoregulation. The initial salinity which induced the decrease of enzyme activity was lower in males than in females, indicating that females were more tolerant to elevated salinities than males from the point of digestive biochemical modulation.

  13. Preparation of gradually componential metal electrode on solution-casted Nafion membrane.

    Science.gov (United States)

    Chung, Ren-Jei; Chin, Tsung-Shune; Chen, Li-Chun; Hsieh, Ming-Fa

    2007-11-01

    A typical ionic polymer-metal composite consists of a thin perfluorinated ionomer membrane and noble metal electrodes plated on both surfaces. It undergoes a large bending motion when an electric field is applied hence exhibits deformation by a certain amount of cation. With proper arrangement and package, a great number of "smart devices" are anticipated. In this study, a solution-cast route was used to prepare the electro-active polymer membrane and platinum electrodes were fabricated onto the membrane through electro-less plating. The ionic polymer used is the commercial Nafion, the perfluoro-sulfonated ionomer membrane, developed by DuPont Co. Nafion membrane was cast by the solution-casting route and then loaded with different weights simultaneously. The optimized processing conditions, membrane properties and electrodes behaviors were investigated. The results of shift in WAXD peaks showed that weights delineated the crystallinity of the solution-cast membranes. The number and size of the crystalline domains of solution-cast membrane decrease as studied by SAXS. The Young's modulus of solution-cast membrane decreases as increasing weight because of the loss of crystallinity (180-140 MPa). A finely dispersed platinum particle deeper and gradient penetrating within the near-boundary region with a smaller average particle size and more uniform distribution could be obtained through a reverse electro-less plating. Its surface roughness is 3 nm comparing to 52 nm of a typical process. But its surface resistance is too high (3.5 Omega) to activate the bending motion. To solve this problem, we coated the second Pt electrodes by a typical electro-less plating, and the resistance decreased to 0.7 Omega. The results depicted that the fabricated IPMC shows longer bending lifetime than typical IPMC. In a 0.09% NaCl solution, the device was able to vibrate for 8h under a 5 V, 0.1 Hz actuation.

  14. Gradual Incorporation of Whole Wheat Flour into Bread Products for Elementary School Children Improves Whole Grain Intake

    Science.gov (United States)

    Rosen, Renee A.; Sadeghi, Lelia; Schroeder, Natalia; Reicks, Marla M.; Marquart, Len

    2008-01-01

    Purpose: Whole grain intake is associated with health benefits but current consumption by children is only about one-third of the recommended level. The purpose of this study was to test the feasibility of an innovative approach whereby the whole wheat content of bread products in school lunches was gradually increased to increase whole grain…

  15. A simple mathematical model of gradual Darwinian evolution: emergence of a Gaussian trait distribution in adaptation along a fitness gradient.

    Science.gov (United States)

    Biktashev, Vadim N

    2014-04-01

    We consider a simple mathematical model of gradual Darwinian evolution in continuous time and continuous trait space, due to intraspecific competition for common resource in an asexually reproducing population in constant environment, while far from evolutionary stable equilibrium. The model admits exact analytical solution. In particular, Gaussian distribution of the trait emerges from generic initial conditions.

  16. Characterization of the hydrogeology and stress state in the vicinity of the homestake mine, Lead, SD

    Science.gov (United States)

    Ebenhack, Johnathan Foss

    around the Homestake mine. This was done by varying the rock density, Poisson's ratio, the effective Young's modulus of the workings region, and including initial stresses until predicted stresses best fit in-situ stress data. The changing mechanical properties in the workings and dewatering cause changes to the stress around the mine. The mining process typically causes increased compression laterally around the workings and decreased compression above, below, and within the workings. The greatest changes in total stress are near the base of the mine and reach roughly 40 MPa between the ore bodies and in the lower portions of the West Ore Body. The softening of the mine region because of material removal and decreased fluid pressure in the workings results in deformation in the vicinity of the mine. Subsidence occurs above the mine region and is greatest near the surface and decreases with depth; above the shallowest workings subsidence can reach approximately 0.18 m. There is also uplift along the footwall of the workings in the deeper portions of the mine that can reach up to 0.022 m. Horizontal displacements of as much as several centimeters occur around the mine and with displacement towards the workings region. Deformation in the vicinity of the mine results in tilt that is towards the workings with the greatest tilts near the surface. A fault that intersects the West Ore Body was considered as a location for an experiment into the mechanics of earthquake nucleation, so the stress state in the vicinity of this feature was of particular interest. This simulation shows that mining and dewatering reduce fluid pressure and change stresses along the fault. The shear stress along the fault typically increases along most of the fault and decreases in the region where the fault and West Ore Body intersect. Increased shear is typically on the order of 1 to 2 MPa but can reach as much as 5 MPa in areas around the intersection of the fault and West Ore Body. In the region

  17. Gradual cessation of milking reduces milk leakage and motivation to be milked in dairy cows at dry-off.

    Science.gov (United States)

    Zobel, G; Leslie, K; Weary, D M; von Keyserlingk, M A G

    2013-08-01

    The effects of gradual versus abrupt cessation of milking at dry-off in dairy cows are not well understood, but gradually reducing milk production in human mothers is known to reduce discomfort and milk leakage. This study compared the effects of abrupt versus gradual cessation of milking on milk leakage and dairy cow behavior. Holstein dairy cows were housed in groups of 6 and randomly assigned to either abrupt milk cessation (i.e., dry-off on d 0) or gradual milk cessation (i.e., skipped milkings beginning on d 0; dry-off on d 5). Four replicates were performed over time, for a total of 24 cows (mean ± SD; parity=2.3±1.2; milk production the day before d 0=24±5 kg/d). Intramammary antibiotic, internal teat sealer, and external teat sealant were administered at dry-off. Measurements were taken from d -3 to 8 relative to dry-off. Three periods were identified for behavior data: baseline (d -3 to 1), period 1 (abrupt cows dry, gradual cows milking; d 0-4), and period 2 (all cows dry; d 5-8). Lying time was recorded with data loggers. Video scan samples (5-min intervals) were used to measure feeding time and motivation to be milked (i.e., standing at the pen's exit gate). Milk leakage was monitored every 20 min during the 2-h period following the milking times of 0500 and 1500 h after complete cessation of milking (period 1 for abrupt vs. period 2 for gradual). Composite milk samples were taken before dry-off (d -1, 0, and 5) and at the start of the next lactation (colostrum, 24h and 7-10 d postcalving) to determine somatic cell score (SCS) and conduct bacteriological examinations in clinical mastitis cases. Regardless of treatment, dry-off resulted in reduced lying time [14.1 vs. 13.2h/d; standard error of the difference (SED)=0.2], reduced lying bouts (10.7 vs. 8.3 bouts/d; SED=0.2), increased lying bout duration (1.4 vs. 1.7h/bout; SED=0.03) and increased feeding time (5.0 vs. 5.9h/d; SED=0.2). Compared with baseline, the odds of standing at the gate increased

  18. BackscatterA [USGS SWATH]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Monterey Canyon and Vicinity map area, California. Backscatter data are provided as separate...

  19. BackscatterD [CSUMB Swath]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the acoustic-backscatter map of Monterey Canyon and Vicinity map area, California. Backscatter data are provided as separate...

  20. Digital Geologic Map of Rocky Mountain National Park and Vicinity, Colorado (NPS, GRD, GRE, ROMO)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of Rocky Mountain National Park and Vicinity, Coloradois comprised of GIS data layers, two ancillary GIS tables, a Windows Help File with...

  1. Geology and geomorphology--Drakes Bay and Vicinity Bay Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the geologic and geomorphic map of the Drakes Bay and Vicinity map area, California. The polygon shapefile is included in...

  2. Basalt microlapilli in deep sea sediments of Indian Ocean in the vicinity of Vityaz fracture zone

    Digital Repository Service at National Institute of Oceanography (India)

    Nath, B.N.; Iyer, S.D.

    Two cores recovered from the flanks of Mid-India oceanic ridge in the vicinity of Vityaz fracture zone consist of discrete pyroclastic layers at various depths. These layers are composed of coarse-grained, angular basaltic microlapilli in which...

  3. Digital Geologic Map of Great Basin National Park and Vicinity, Nevada (NPS, GRD, GRE, GRBA)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of Great Basin National Park and Vicinity, Nevada is composed of GIS data layers, two ancillary GIS tables, a Windows Help File with...

  4. Geology and geomorphology--Monterey Canyon and Vicinity Map Area, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for the geologic and geomorphic map of Monterey Canyon and Vicinity, California. The vector data file is included in...

  5. Life in wind turbines vicinity, effects on health – a review

    Directory of Open Access Journals (Sweden)

    Krystyna Pawlas

    2012-12-01

    Full Text Available The paper presents a short review of scientific papers , and other sources concerning health effects of exposure to noise, infrasounds, electromagnetic radiation and mechanical hazards induced in dwellers living in vicinity of wind farm.

  6. Gradual Warming in the North Atlantic during D-O Events Synchronous with Antarctic and Southern Hemisphere Warmings

    Science.gov (United States)

    Rasmussen, T. L.; Thomsen, E.; Moros, M.

    2016-12-01

    The climate of the last glacial period was interrupted by about 25 rapid oscillations, called Dansgaard-Oeschger events. In the Greenland ice cores, the events consist of an abrupt warming to warm interstadial conditions followed by a more gradual return to cold stadial conditions. Similar abrupt warmings are seen in paleoceanographic proxies from the Nordic seas, and the shifts are apparently linked to perturbations in the ocean thermohaline circulation. The events also occur in the Antarctic ice cores, but the amplitudes here are smaller and the warmings are more gradual and initiated earlier than in the north. The out-of-phase relationship between the north and south is often referred to as the `Bipolar seesaw'. We have studied core SO2 from the Reykjanes Ridge in the central northernmost Atlantic. The results are compared with previously published records from the North Atlantic and correlated with the Greenland and Antarctic ice cores. By means of transfer function analysis and δ18O values from planktic and benthic foraminifera we show that surface and bottom water temperatures in SO2 increased gradually during the Greenland stadials to a maximum at the beginning of the interstadials. The warmings in SO2 follow the timing and gradual warmings observed in the Antarctic ice cores and they are clearly out of phase with the abrupt, delayed warmings over Greenland. Apparently, the surface and intermediate water over most of the Atlantic from the Antarctica to the Scotland-Greenland Ridge warmed and pressed northward at a time when the atmospheric temperatures over Greenland were at minimum and the convection in the Nordic seas stopped. The system appears to function more as a `push-and-pull' system than as a seesaw with a `pull' during the warm interstadials, when convection in the Nordic seas was active and a `push' during the cold stadials, when warm water from the south-central Atlantic pushed northward gradually warming the northernmost Atlantic and Nordic

  7. Transformation of Tertiary Benzyl Alcohols into the Vicinal Halo-Substituted Derivatives Using N-Halosuccinimides

    Directory of Open Access Journals (Sweden)

    Njomza Ajvazi

    2016-10-01

    Full Text Available The efficiency of direct conversion of tertiary alcohols bearing a β-hydrogen atom to vicinal halohydrins—chlorohydrins and bromohydrins—under green reaction conditions was tested preliminarily on model tertiary benzyl alcohols. Tertiary alcohols were successfully directly halogenated to vicinal halohydrins with N-halosuccinimide in aqueous media. The efficiency of the reaction in water was significantly improved in the presence of sodium dodecyl sulphate as the surfactant.

  8. Parameter changes during gradual flooding of a PEM fuel cell through EIS studies; Cambio en parametros de una celda de combustible PEM durante inundacion gradual mediante estudios de EIS

    Energy Technology Data Exchange (ETDEWEB)

    Cano Castillo, Ulises; Cruz Manzo, Samuel; Arriaga Hurtado, Gerardo [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Ortiz, Alondra; Orozco, German [Centro de Investigacion y Desarrollo Tecnologico en Electroquimica S.C. (CIDETEQ) (Mexico)

    2008-07-01

    The gradual flooding of a single PEM fuel cell was produced and Electrochemical Impedance Spectroscopy (EIS) measurements were realized in order to follow changes of the fuel cell impedance parameters. These changes were followed by using two equivalent circuit models: one simple model of the Randles type accounting for cathode and anode interfaces and a more complex model based on distributed elements, more suitable for porous electrodes in order to include protonic resistance of the catalyst layers. [Spanish] La inundacion gradual de una monocelda de combustible tipo PEM fue estudiada empleando espectroscopia de impedancia electroquimica (EIS), con el proposito de seguir cambios en los parametros de impedancia de la celda. Estos cambios fueron estudiados utilizando dos circuitos equivalentes: un modelo simple de tipo Randles, el cual considerara las interfaces del catodo y del anodo, y un modelo mas complejo basado en elementos distribuidos, el cual fuera adecuado para electrodos porosos, a fin de incluir la resistencia protonica de las capas catalizadoras.

  9. Landsat - SRTM Shaded Relief Comparison, Los Angeles and Vicinity

    Science.gov (United States)

    2002-01-01

    Digital elevation models (DEMs), such as those produced by the Shuttle Radar Topography Mission (SRTM), allow user-controlled visualization of the Earth's landforms that is not possible using satellite imagery alone. This three-view comparison shows Los Angeles, Calif., and vicinity, with a Landsat image (only) on the left, a shaded relief rendering of the SRTM DEM on the right, and a merge of the two data sets in the middle. Note that topographic expression in the Landsat image alone is very subtle due to the fairly high sun angle (63 degrees above the horizon) during the satellite overflight in late morning of a mid-Spring day (May 4, 2001). In contrast, computer generated topographic shading of the DEM provides a pure and bold image of topographic expression with a user specified illumination direction. The middle image shows how combining the Landsat and DEM shaded relief can result in a topographically enhanced satellite image in which the information content of both data sets is merged into a single view.Landsat has been providing visible and infrared views of the Earth since 1972. SRTM elevation data matches the 30-meter (98-foot) resolution of most Landsat images and helps in analyzing the large and growing Landsat image archive, managed by the U.S. Geological Survey (USGS).Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect 3-D measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter (approximately 200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Imagery and Mapping Agency (NIMA) of the U

  10. An extension of the transfer matrix method to analyzing acoustic resonators with gradually varying cross-sectional area

    Science.gov (United States)

    Min, Qi; He, Wan-Quan; Wang, Quan-Biao; Tian, Jia-Jin

    2016-11-01

    The transfer matrix method was used to analyze the acoustical properties of stepped acoustic resonator in the previous paper. The present paper extends the application of the transfer matrix method to analyzing acoustic resonators with gradually varying cross-sectional area. The transfer matrices and the resonant conditions are derived for acoustic resonators with four different kinds of gradually varying geometric shape: tapered, trigonometric, exponential and hyperbolic. Based on the derived transfer matrices, the acoustic properties of these resonators are derived, including the resonant frequency, phase and radiation impedance. Compared with other analytical methods based on the wave equation and boundary conditions, the transfer matrix method is simple to implement and convenient for computation.

  11. A 3-step gradual dilation method: a new safe technique of percutaneous endoscopic gastrostomy for obstructive esophageal cancer.

    Science.gov (United States)

    Takeshita, Nobuyoshi; Uesato, Masaya; Shuto, Kiyohiko; Shiratori, Toru; Kono, Tsuguaki; Akutsu, Yasunori; Hoshino, Isamu; Horibe, Daisuke; Narushima, Kazuo; Imanishi, Shunsuke; Maruyama, Tetsuro; Semba, Yoshihide; Toyozumi, Takeshi; Matsubara, Hisahiro

    2014-08-01

    Although percutaneous endoscopic gastrostomy (PEG) is the preferred method to provide enteral nutrition for a longer time period, in obstructive esophageal cancer, we cannot safely perform endoscopic access to the stomach even with the ultrathin endoscope. We experienced 1 fatal case due to esophageal perforation caused by balloon dilation, and hence, we developed a safer method. We treated 4 patients with obstructive esophageal cancer using a 3-step gradual dilation method with nasogastric tubes (from 8 to 16 Fr). After about 2 weeks of initial dilation, we could safely perform endoscopic access to the stomach with the ultrathin endoscope and PEG placement using the introducer technique. The 3-step gradual dilation method is a safe and easy procedure for endoscopic access to the stomach. It can be used to provide enteral access as a palliative treatment for patients with obstructive esophageal cancer that is not suitable for conventional PEG placement.

  12. Palynological evidence for gradual vegetation and climate changes during the African Humid Period termination at 13°N from a Mega-Lake Chad sedimentary sequence

    Directory of Open Access Journals (Sweden)

    P. G. C. Amaral

    2013-01-01

    decrease in mean Pann estimates to approximately 600 (−230/+600 mm. But, the constant significant presence of lowland humid taxa until ca. 5000 cal yr BP, contemporaneous with a slight increase in steppic taxa, demonstrates that at this date, the modern vegetation was not yet established in the vicinity of Lake Chad. Our data indicate that between ca. 6700 and ca. 5000 cal yr BP vegetation and climate changes must have occurred progressively, but that century-scale climate variability was superimposed on this long-term mid-Holocene drying trend as observed around ca. 6300 cal yr BP, where pollen data indicate more humid conditions.

  13. After 20 years of status quo: the failure of gradualism in Slovenia’s post-socialist transition

    OpenAIRE

    Spruk, Rok

    2012-01-01

    In the past 20 years, the Slovenia has been praised as the richest former socialist country, having accomplished the advancement from borrower into donor status at the World Bank and having entered the European Monetary Union as the first country from former socialist block. In the due course of transition to market, Slovenia adopted the gradualist approach to economic reform, emphasizing gradual privatization, excessive regulation of the labor market and financial sector as well as the slow ...

  14. Switching to Clozapine Using Immediate Versus Gradual Antipsychotic Discontinuation: A Pilot, Double-Blind, Randomized Controlled Trial.

    Science.gov (United States)

    Takeuchi, Hiroyoshi; Lee, Jimmy; Fervaha, Gagan; Foussias, George; Agid, Ofer; Remington, Gary

    2017-02-01

    To examine effects of different antipsychotic discontinuation strategies on clinical outcomes in patients with schizophrenia undergoing a switch to clozapine. This pilot, 8-week, double-blind, randomized controlled trial was conducted from May 1999 to July 2004. Outpatients with a diagnosis of schizophrenia or schizoaffective disorder based on the Structured Clinical Interview for DSM-IV and eligible for a switch to clozapine were included. Participants were randomly assigned to the immediate discontinuation (prior antipsychotics were discontinued at baseline) or gradual discontinuation (prior antipsychotics were reduced by 25% each week) group. For each group, clozapine was gradually increased to 300 mg/d at day 12, with this dose maintained for 3 weeks and thereafter adjusted as needed. Clinical outcome measures included the Brief Psychiatric Rating Scale (BPRS), UKU Side Effect Rating Scale, and extrapyramidal symptoms scales. Thirty-three patients were enrolled; 15 and 18 patients were assigned to the immediate and gradual discontinuation groups, respectively. While significant improvements were observed in BPRS total scores after the switch to clozapine in both groups (P values clozapine in patients with schizophrenia; however, due to the small sample size, larger-scale trials are needed to confirm these results. ClinicalTrials.gov identifier: NCT02640300.

  15. Gradual Increase of FcγRIIIa/CD16a Expression and Shift toward IFN-γ Secretion during Differentiation of CD56dim Natural Killer Cells

    Directory of Open Access Journals (Sweden)

    Laurie Lajoie

    2017-11-01

    Full Text Available Natural killer (NK cell effector functions include cytotoxicity and secretion of cytokines such as interferon-γ (IFN-γ. The immature CD56bright subset of human NK cells lacks expression of FcγRIIIa/CD16a, one of the low-affinity immunoglobulin G receptors, or exhibits low-density expression (CD56brightCD16−/dim and produces IFN-γ in response to cytokine stimulation, whereas the mature CD56dimCD16+ subset is the most cytotoxic one. A further differentiation/maturation of the latter subset according to the gradual loss of NKG2A and/or gain of KIR2DL (CD158a and CD158b has been demonstrated and the ability to produce IFN-γ in response to activating receptor (AR co-engagement is gradually acquired during terminal differentiation. In the course of flow cytometry analysis of CD56dim NK cells, we noted a substantial intraindividual heterogeneity of expression of FcγRIIIa. FcγRIIIa is unique among ARs: it does not require the co-engagement of other ARs to induce substantial cytotoxicity or cytokine synthesis in CD56dim cells. We, therefore, investigated whether individual differentiation/maturation of polyclonal CD56dim NK cells defined by expression of NKG2A/KIR2DL is related to FcγRIIIa expression and to the heterogeneity of NK cell responses upon FcγRIIIa engagement. When we analyzed unstimulated CD56dim cells by increasing level of FcγRIIIa expression, we found that the proportion of the more differentiated CD158a,h+ and/or CD158b,j+ cells and that of the less differentiated NKG2A+ cells gradually increased and decreased, respectively. FcγRIIIa engagement by using plate-bound murine anti-CD16 monoclonal antibody (mAb or rituximab or trastuzumab (two therapeutic mAbs, resulted in donor-dependent partial segregation of IFN-γ-producing and/or degranulating CD56dim cells. Importantly, the proportion of CD158a,h/b,j+ cells and that of NKG2A+ cells was increased and decreased, respectively, IFN-γ-producing cells, whereas these proportions

  16. Tilt boundary formation in GeSi/Si (001 vicinal heterosystem

    Directory of Open Access Journals (Sweden)

    Aleksei V. Kolesnikov

    2015-03-01

    Full Text Available The structural state of GexSi1-x films grown on Si substrates with the vicinal orientation (1 1 13 has been studied. The (1 1 13 orientation has been obtained by rotating the singular plane (001 around the [1 1 ¯0] axis. The x parameter of GexSi1-x films in different samples ranged from 0.083 to 0.268. Triclinic distortions arising in film crystal lattice have been analyzed using our technique developed for the determination of epitaxial layer structural parameters based on the X-ray diffractometry data. It has been established that during the epitaxial process the film lattice turns around the direction of surface steps due to the introduction of misfit dislocations into the interface. Dislocations with Burgers vector a/2〈110〉 which is not parallel to the interface create an analog of a tilt boundary. The turning angle value ψ is proportional to the misfit dislocation density. This phenomenon is associated with a decrease of the interface symmetry that leads to a change in the efficiency of stress relieving by dislocations belonging to different families. The influence of these families on the low-angle boundary formation is considered. Experimental values of the ψ angle and shear strain for the [13 13 2¯] and [1¯ 1 0] directions lying in the interface (1 1 13 have been defined. A comparison of the experimental and calculated values of ψ for the [13 13 2¯] direction is provided.

  17. Unidirectional lateral nanowire formation during the epitaxial growth of GaAsBi on vicinal substrates

    Science.gov (United States)

    Collar, Kristen N.; Li, Jincheng; Jiao, Wenyuan; Kong, Wei; Brown, April S.

    2018-01-01

    We report on enhanced control of the growth of lateral GaAs nanowires (NWs) embedded in epitaxial (100) GaAsBi thin films enabled by the use of vicinal substrates and the growth-condition dependent role of Bi as a surfactant. Enhanced step-flow growth is achieved through the use of vicinal substrates and yields unidirectional nanowire growth. The addition of Bi during GaAsBi growth enhances Ga adatom diffusion anisotropy and modifies incorporation rates at steps in comparison to GaAs growth yielding lower density but longer NWs. The NWs grown on vicinal substrates grew unidirectionally towards the misorientation direction when Bi was present. The III/V flux ratio significantly impacts the size, shape and density of the resulting NWs. These results suggest that utilizing growth conditions which enhance step-flow growth enable enhanced control of lateral nanostructures.

  18. Experimental photophysical characterization of fluorophores in the vicinity of gold nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Rosa, J P; Baptista, P V [CIGMH, Departamento de Ciencias da Vida, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica (Portugal); Lima, J C, E-mail: pmvb@fct.unl.pt, E-mail: lima@dq.fct.unl.pt [REQUIMTE, Departamento de Quimica, Faculdade de Ciencias e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica (Portugal)

    2011-10-14

    We propose an experimental-based tool for dealing with fluorescence modulation close to nanoparticles for application in studies of fluorophores in the vicinity of gold nanoparticles (AuNPs), typically addressed via theoretical models. We performed a photophysical characterization of fluorophores in the vicinity of AuNPs, showing that correct {Phi}{sub F} determination suffers from a local pH effect, and address the observed radiative enhancement. Our approach is based on the experimental assurance that the reference fluorophores are in the same optical conditions as those of the AuNP-fluorophore conjugates. We demonstrate the relevance for introducing corrections for the inner filter effect and the reabsorption of the emitted light caused by AuNPs. The proposed approach could circumvent the need for theoretical based corrections and allow for more accurate determination of fluorescence emission in the vicinity of gold nanoparticles.

  19. Cost-Performance Parametrics for Transporting Small Packages to the Mars Vicinity

    Science.gov (United States)

    McCleskey, C.; Lepsch, Roger A.; Martin, J.; Popescu, M.

    2015-01-01

    This paper explores the costs and performance required to deliver a small-sized payload package (CubeSat-sized, for instance) to various transportation nodes en route to Mars and near-Mars destinations (such as Mars moons, Phobos and Deimos). Needed is a contemporary assessment and summary compilation of transportation metrics that factor both performance and affordability of modern and emerging delivery capabilities. The paper brings together: (a) required mass transport gear ratios in delivering payload from Earths surface to the Mars vicinity, (b) the cyclical energy required for delivery, and (c) the affordability and availability of various means of transporting material across various Earth-Moon vicinity and Near-Mars vicinity nodes relevant to Mars transportation. Examples for unit deliveries are computed and tabulated, using a CubeSat as a unit, for periodic near-Mars delivery campaign scenarios.

  20. Delayed initiation but not gradual advancement of enteral formula feeding reduces the incidence of necrotizing enterocolitis (NEC in preterm pigs.

    Directory of Open Access Journals (Sweden)

    Nada Ghoneim

    Full Text Available Enteral formula feeding is a risk factor for necrotizing enterocolitis (NEC in premature infants, yet studies are conflicting regarding the safest timing for introduction and advancement of feeds. Our aim was to test the effects of early vs. late initiation and abrupt vs. gradual advancement of enteral feeding of an intact vs. hydrolyzed protein formula on NEC incidence and severity in preterm pigs. In Experiment 1, preterm pigs received total parenteral nutrition (TPN at birth with abrupt initiation of enteral formula feeds (50% full intake on d of life (DOL 2 (EA or 5 (LA while PN continued. Pigs were also fed formula containing either intact or hydrolyzed protein. In Experiment 2, preterm pigs received TPN at birth with enteral, hydrolyzed-protein formula feeds introduced on DOL 2 either abruptly (EA; 50% full feeds or gradually (EG; 10-50% full feeds over 5 d while PN continued. NEC incidence and severity were assessed based on macroscopic and histological scoring. In Experiment 1, NEC incidence (41% vs. 70%, P<0.05 and severity were reduced in LA vs. EA groups and LA was associated with a higher survival rate, daily weight gain and jejunum villus height. Piglets fed hydrolyzed vs. intact protein formula had lower stomach content weights and similar NEC incidence. In Experiment 2, NEC incidence and severity were not different between pigs the EG vs. EA group. Proinflammatory gene expression (IL-1β, IL-6 and S100A9 in the ileum was lower in both LA and EG vs. EA groups. In conclusion, delayed initiation but not gradual advancement of enteral feeding is protective against NEC in preterm pigs. Feeding hydrolyzed vs. intact protein formula improved gastric transit without affecting the NEC incidence.

  1. The focusing effect of electromagnetic waves in two-dimensional photonic crystals with gradually varying lattice constant

    Directory of Open Access Journals (Sweden)

    F Bakhshi Garmi

    2016-02-01

    Full Text Available In this paper we studied the focusing effect of electromagnetic wave in the two-dimensional graded photonic crystal consisting of Silicon rods in the air background with gradually varying lattice constant. The results showed that graded photonic crystal can focus wide beams on a narrow area at frequencies near the lower edge of the band gap, where equal frequency contours are not concave. For calculation of photonic band structure and equal frequency contours, we have used plane wave expansion method and revised plane wave expansion method, respectively. The calculation of the electric and magnetic fields was performed by finite difference time domain method.

  2. The Nature of Surface States on Vicinal Cu (775): An STM and Photoemission Study

    OpenAIRE

    Zaki, Nader; Knox, Kevin; Osgood, Richard M.; Johnson, Peter D.; Fujii, Jun; Vobornik, Ivana; Panaccione, Giancarlo

    2014-01-01

    We report ARPES and a set of in situ STM measurements on a narrow-terrace-width vicinal Cu(111) crystal surface, Cu(775), whose vicinal cut lies close to the transition between terrace and step modulation. These measurements show sharp zone-folding (or Umklapp) features with a periodicity in k||, indicating that the predominant reference plane is that of Cu(775), i.e. that the surface is predominately step-modulated. Our measurements also show variation in Umklapp intensity with photon energy...

  3. The oriental fruit fly, Bactrocera dorsalis, in China: origin and gradual inland range expansion associated with population growth.

    Science.gov (United States)

    Wan, Xuanwu; Nardi, Francesco; Zhang, Bin; Liu, Yinghong

    2011-01-01

    The oriental fruit fly, Bactrocera dorsalis, expanded throughout mainland China in the last century to become one of the most serious pests in the area, yet information on this process are fragmentary. Three mitochondrial genes (nad1, cytb and nad5) were used to infer the genetic diversity, population structure and demographic history of the oriental fruit fly from its entire distribution range in China. High levels of genetic diversity, as well as a significant correspondence between genetic and geographic distances, suggest that the invasion process might have been gradual, with no associated genetic bottlenecks. Three population groups could be identified, nevertheless the overall genetic structure was weak. The effective number of migrants between populations, estimated using the coalescent method, suggested asymmetric gene flow from the costal region of Guangdong to most inland regions. The demographic analysis indicates the oriental fruit fly underwent a recent population expansion in the Central China. We suggest the species originated in the costal region facing the South China Sea and gradually expanded to colonize mainland China, expanding here to high population numbers.

  4. BathymetryB Hillshade [5m]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for 2-m and 5-m bathymetry and shaded-relief maps of Monterey Canyon and Vicinity, California. The raster data file is included in...

  5. BathymetryA [2m]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for 2-m and 5-m bathymetry and shaded-relief maps of Monterey Canyon and Vicinity, California. The raster data file is included in...

  6. BathymetryB [5m]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for 2-m and 5-m bathymetry and shaded-relief maps of Monterey Canyon and Vicinity, California. The raster data file is included in...

  7. BathymetryA Hillshade [2m]--Monterey Canyon and Vicinity, California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents data for 2-m and 5-m bathymetry and shaded-relief maps of Monterey Canyon and Vicinity, California. The raster data file is included in...

  8. Properties of Soils and Plants Uptake within the Vicinity of Selected ...

    African Journals Online (AJOL)

    Backyard farming is becoming popular among the auto mechanics near their workshops where spent engine oil and carcass of vehicles are continuously dumped in Nigeria. The properties of soil and maize plants sampled from the vicinity of selected auto mechanic workshops in Ile-Ife, Nigeria were investigated. The results ...

  9. Assessment of pollution trend of heavy metals in soils in the vicinity ...

    African Journals Online (AJOL)

    Topsoil and subsoil obtained in the vicinity of the Nigerian Gas Company were digested and analysed for some selected trace metals using atomic absorption spectrophotometer of model pye unicam SP 2900. The trace metals determined include nickel, copper, iron, barium, lead, cadmium and zinc respectively.

  10. Formation and sintering of Pt nanopartictes on vicinal rutile TiO2 surfaces

    DEFF Research Database (Denmark)

    Rieboldt, Felix; Helveg, S.; Bechstein, Ralf

    2014-01-01

    By means of scanning tunnelling microscopy (STM) the nucleation, growth and sintering of platinum nanoparticles (Pt NP's) was studied on vicinal and flat rutile titanium dioxide (TiO2) surfaces. Utilising physical vapour deposition, the nucleation of Pt NP's on TiO2 surfaces at room temperature (...

  11. [Analysis of optical emission spectra from ICP of Ar in the vicinity of plasma sheath].

    Science.gov (United States)

    Zhao, Wen-Feng; Chen, Jun-Fang; Meng, Ran

    2009-11-01

    In order to control the ion density and energy distribution in the vicinity of plasma sheath independently, the inductively coupled plasma and its glow discharge mechanism in the vicinity of plasma sheath were studied by means of optical emission spectroscopy (OES) under different RF power, different discharge and different substrate DC bias voltage. It was shown that the ion density is higher and the electron temperature is lower in the vicinity of inductively coupled plasma sheath according to the ionic line and atomic line. With changing the discharge pressure and RF power, the spectral characteristics analysis shows that the ion density in the vicinity of plasma sheath linearly increases with the RF power and rises with the pressure under the low pressure. The atomic spectral intensity of low excitation states increases rapidly. The atomic spectral intensity of high excitation states rises slowly and the intensity of ion spectrum increases not obviously. By applying the DC bias voltage to substrate, the intensity of emission spectroscopy was analyzed. The result shows that the intensity of spectra rises with the increase in positive bias voltage, while first reduces then increases with the increase in negative bias voltage, and is the weakest in the case of DC bias at -30 V. This shows that the fast ions and the electrons are the main source of energy for Ar ionization and excitation.

  12. Revised Hydrogeology for the Suprabasalt Aquifer System, 200-West Area and Vicinity, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Bruce A.; Bjornstad, Bruce N.; Schalla, Ronald; Webber, William D.

    2002-05-14

    The primary objective of this study was to refine the conceptual groundwater flow model for the 200-West Area and vicinity. This is the second of two reports that combine to cover the 200 Area Plateau, an area that holds the largest inventory of radionuclide and chemical waste on the Hanford Site.

  13. Revised Hydrogeology for the Suprabasalt Aquifer System, 200-East Area and Vicinity, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Bruce A.; Bjornstad, Bruce N.; Schalla, Ronald; Webber, William D.

    2000-04-20

    This study supports the Hanford Groundwater/Vadose integration project objectives to better understand the risk of groundwater contamination and potential risk to the public via groundwater flow paths. The primary objective of this study was to refine the conceptual groundwater flow model for the 200-East Area and vicinity.

  14. Surface-water quality, Oneida Reservation and vicinity, Wisconsin, 1997-98

    Science.gov (United States)

    Schmidt, Morgan A.; Scudder, Barbara C.; Richards, Kevin D.

    2000-01-01

    Streamwater samples were collected at 19 sites in the vicinity of the Oneida Tribe of Indians of Wisconsin Reservation. Samples were collected during 5 sampling periods in 1997-98. Field measurements were made and samples were analyzed for nutrients, suspended sediment, major ions, and pesticides.

  15. Parental smoking in the vicinity of children and tobacco control policies in the European region

    NARCIS (Netherlands)

    Kovess, V.; Pilowsky, D.J.; Boyd, A.; Pez, O.; Bitfoi, A.; Carta, M.G.; Eke, C.; Golitz, D.; Kuijpers, R.C.W.M.; Lesinskiene, S.; Mihova, Z.; Otten, R.; Susser, E.

    2013-01-01

    Objective: To ascertain patterns of parental smoking in the vicinity of children in Eastern and Western Europe and their relation to Tobacco Control Scale (TCS) scores. Methods: Data on parental smoking patterns were obtained from the School Child Mental Health Europe (SCMHE), a 2010

  16. 14 CFR 91.137 - Temporary flight restrictions in the vicinity of disaster/hazard areas.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Temporary flight restrictions in the vicinity of disaster/hazard areas. 91.137 Section 91.137 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT RULES Flight Rules General §...

  17. Series Resistance Monitoring for Photovoltaic Modules in the Vicinity of MPP

    DEFF Research Database (Denmark)

    Sera, Dezso

    2010-01-01

    the time period with reduced power production. This paper focuses on the estimation of series resistance of flat silicone PV panels or arrays during operation, in the vicinity of their MPP. The method presented in this paper helps to detect failures by monitoring changes in the panel’s or array’s series...

  18. Establishment of background radiation dose rate in the vicinity of the ...

    African Journals Online (AJOL)

    The absorbed dose rate in air in the vicinity of the proposed Manyoni uranium mining project located in Singida region, Tanzania, was determined so as to establish the baseline data for background radiation dose rate data prior to commencement of uranium mining activities. Twenty stations in seven villages were selected ...

  19. 77 FR 71493 - Amendment of VOR Federal Airway V-8 in the Vicinity of Rifle, CO

    Science.gov (United States)

    2012-12-03

    ...This action amends VHF Omnidirectional Range (VOR) Federal Airway V-8 in the vicinity of Rifle, CO, to correct the description contained in part 71 to ensure it matches the information contained in the FAA's aeronautical database, matches the depiction on the associated charts, and to ensure the safety and efficiency of the National Airspace System (NAS).

  20. Parental smoking in the vicinity of children and tobacco control policies in the European region

    NARCIS (Netherlands)

    Kovess, V.; Pilowsky, D.J.; Boyd, A.; Pez, O.; Bitfoi, A.; Carta, M.G.; Eke, C.; Golitz, D.; Kuijpers, R.C.W.M.; Lesinskiene, S.; Mihova, Z.; Otten, R.; Susser, E.S.

    2013-01-01

    Objective: To ascertain patterns of parental smoking in the vicinity of children in Eastern and Western Europe and their relation to Tobacco Control Scale (TCS) scores. Methods: Data on parental smoking patterns were obtained from the School Child Mental Health Europe (SCMHE), a 2010 cross-sectional

  1. Discontinuation of benzodiazepines among older insomniac adults treated with cognitive-behavioural therapy combined with gradual tapering: a randomized trial.

    Science.gov (United States)

    Baillargeon, Lucie; Landreville, Philippe; Verreault, René; Beauchemin, Jean-Pierre; Grégoire, Jean-Pierre; Morin, Charles M

    2003-11-11

    Long-term use of hypnotics is not recommended because of risks of dependency and adverse effects on health. The usual clinical management of benzodiazepine dependency is gradual tapering, but when used alone this method is not highly effective in achieving long-term discontinuation. We compared the efficacy of tapering plus cognitive-behavioural therapy for insomnia with tapering alone in reducing the use of hypnotics by older adults with insomnia. People with chronic insomnia who had been taking a benzodiazepine every night for more than 3 months were recruited through media advertisements or were referred by their family doctors. They were randomly assigned to undergo either cognitive-behavioural therapy plus gradual tapering of the drug (combined treatment) or gradual tapering only. The cognitive-behavioural therapy was provided by a psychologist in 8 weekly small-group sessions. The tapering was supervised by a physician, who met weekly with each participant over an 8-week period. The main outcome measure was benzodiazepine discontinuation, confirmed by blood screening performed at each of 3 measurement points (immediately after completion of treatment and at 3- and 12-month follow-ups). Of the 344 potential participants, 65 (mean age 67.4 years) met the inclusion criteria and entered the study. The 2 study groups (35 subjects in the combined treatment group and 30 in the tapering group) were similar in terms of demographic characteristics, duration of insomnia and hypnotic dosage. Immediately after completion of treatment, a greater proportion of patients in the combined treatment group had withdrawn from benzodiazepine use completely (77% [26/34] v. 38% [11/29]; odds ratio [OR] 5.3, 95% confidence interval [CI] 1.8-16.2; OR after adjustment for initial benzodiazepine daily dose 7.9, 95% CI 2.4-30.9). At the 12-month follow-up, the favourable outcome persisted (70% [23/33] v. 24% [7/29]; OR 7.2, 95% CI 2.4-23.7; adjusted OR 7.6, 95% CI 2.5-26.6); similar

  2. Vicinity of Schools, But Not of Residences, Seems to Regulate Physical and Sports Activities of 13-Year-Old Teenagers in a South European Setting.

    Science.gov (United States)

    Magalhães, Alexandre; Ramos, Elisabete; Pina, Maria Fátima

    2017-01-01

    Proximity to urban green spaces (UGS) and open sports spaces (OSS) benefits health, promotes physical activity (PA) and sports practice (SP). Analyze the association between PA or SP according to distances between UGS or OSS and teenagers' residences or schools. We evaluated 1333 (53.9% girls) teenagers (13 years old) living and studying in Porto, Portugal (EPITeen cohort). PA was classified as light or moderate/vigorous. Distances were the shortest routes from residences or schools to UGS/OSS, and classified in ≤250 m; >250 m to ≤500 m; >500 m to ≤750 m; >750 m. Chi-square test and chi-square for trends were used to compare proportions; associations were measured using logistic regression, through odds ratio and 95% confidence intervals, adjusting to BMI and parental education. Regarding vicinity' of schools, the prevalence of moderate/vigorous PA among boys, decreases as distances to OSS increases. For girls, the prevalence of sports decreases as distances to UGS increase. For boys, we found an association between moderate/vigorous PA and proximity to OSS in the vicinity of schools: considering ≤250 m as reference, the odds of moderate/vigorous PA is 0.20 (0.06-0.63) for >250 m to ≤500 m; 0.21 (0.07-0.61) for >500 m to ≤750 m and 0.19 (0.06-0.58) for >750 m. Vicinities of schools seem to influence teenagers to be more physically active and increase sports participation.

  3. Parental smoking in the vicinity of children and tobacco control policies in the European region.

    Science.gov (United States)

    Kovess, Viviane; Pilowsky, Daniel J; Boyd, Anders; Pez, Ondine; Bitfoi, Adina; Carta, Mauro; Eke, Ceyda; Golitz, Dietmar; Kuijpers, Rowella; Lesinskiene, Sigita; Mihova, Zlatka; Otten, Roy; Susser, Ezra

    2013-01-01

    To ascertain patterns of parental smoking in the vicinity of children in Eastern and Western Europe and their relation to Tobacco Control Scale (TCS) scores. Data on parental smoking patterns were obtained from the School Child Mental Health Europe (SCMHE), a 2010 cross-sectional survey of 5141 school children aged 6 to 11 years and their parents in six countries: Germany, Netherlands, Lithuania, Romania, Bulgaria and Turkey ranked by TCS into three level categories toward tobacco control policies. A slightly higher proportion of Eastern compared to Western European mothers (42.4 vs. 35.1%) were currently smoking in but the difference was not statistically significant after adjusting for maternal age and maternal educational attainment. About a fifth (19.3%) and a tenth (10.0%) of Eastern and Western European mothers, respectively, smoked in the vicinity of their children, and the difference was significant even after adjustment for potential confounders (pParents with the highest educational attainment were significantly less likely to smoke in the vicinity of their children than those with the lowest attainment. After control of these covariates lax tobacco control policies, compared to intermediate policies, were associated with a 50% increase in the likelihood of maternal smoking in the vicinity of children adjusted odds ratio (AOR) = 1.52 and 1.64. Among fathers, however, the relationship with paternal smoking and TCS seems more complex since strict policy increases the risk as well AOR = 1,40. Only one country, however belongs to the strict group. Tobacco control policies seem to have influenced maternal smoking behaviors overall to a limited degree and smoking in the vicinity of children to a much greater degree. Children living in European countries with lax tobacco control policies are more likely to be exposed to second hand smoking from maternal and paternal smoking.

  4. Parental smoking in the vicinity of children and tobacco control policies in the European region.

    Directory of Open Access Journals (Sweden)

    Viviane Kovess

    Full Text Available OBJECTIVE: To ascertain patterns of parental smoking in the vicinity of children in Eastern and Western Europe and their relation to Tobacco Control Scale (TCS scores. METHODS: Data on parental smoking patterns were obtained from the School Child Mental Health Europe (SCMHE, a 2010 cross-sectional survey of 5141 school children aged 6 to 11 years and their parents in six countries: Germany, Netherlands, Lithuania, Romania, Bulgaria and Turkey ranked by TCS into three level categories toward tobacco control policies. RESULTS: A slightly higher proportion of Eastern compared to Western European mothers (42.4 vs. 35.1% were currently smoking in but the difference was not statistically significant after adjusting for maternal age and maternal educational attainment. About a fifth (19.3% and a tenth (10.0% of Eastern and Western European mothers, respectively, smoked in the vicinity of their children, and the difference was significant even after adjustment for potential confounders (p<0.001. Parents with the highest educational attainment were significantly less likely to smoke in the vicinity of their children than those with the lowest attainment. After control of these covariates lax tobacco control policies, compared to intermediate policies, were associated with a 50% increase in the likelihood of maternal smoking in the vicinity of children adjusted odds ratio (AOR = 1.52 and 1.64. Among fathers, however, the relationship with paternal smoking and TCS seems more complex since strict policy increases the risk as well AOR = 1,40. Only one country, however belongs to the strict group. SIGNIFICANCE: Tobacco control policies seem to have influenced maternal smoking behaviors overall to a limited degree and smoking in the vicinity of children to a much greater degree. Children living in European countries with lax tobacco control policies are more likely to be exposed to second hand smoking from maternal and paternal smoking.

  5. Decreases in Human Semen Quality with Age Among Healthy Men

    Energy Technology Data Exchange (ETDEWEB)

    Eskenazi, B.; Wyrobek, A.J.; Kidd, S.A.; Moore, L.; Young, S.S.; Moore, D.

    2001-12-01

    The objective of this report is to characterize the associations between age and semen quality among healthy active men after controlling for identified covariates. Ninety-seven healthy, nonsmoking men between 22 and 80 years without known fertility problems who worked for or retired from a large research laboratory. There was a gradual decrease in all semen parameters from 22-80 years of age. After adjusting for covariates, volume decreased 0.03 ml per year (p = 0.001); sperm concentration decreased 2.5% per year (p = 0.005); total count decreased 3.6% per year of age (p < 0.001); motility decreased 0.7% per year (P < 0.001); progressive motility decreased 3.1% per year (p < 0.001); and total progressively motile sperm decreased 4.8% per year (p < 0.001). In a group of healthy active men, semen volume, sperm concentration, total sperm count, and sperm motility decrease continuously between 22-80 years of age, with no evidence of a threshold.

  6. Hydrogen isotopes of leaf lipids indicate gradual hydrologic transition at the end of the African Humid Period

    Science.gov (United States)

    Beckmann, Britta; Haese, Barbara; Werner, Martin; Schefuß, Enno

    2013-04-01

    The hydrologic evolution of the NW African monsoon system over the Holocene, in particular during abrupt climate changes like the end of the African Humid Period (AHP) is not yet fully understood. The dust record at ODP Site 658C (DeMenocal et al., 2000) for example suggests an abrupt end of the AHP with a sudden desertification in the mid-Holocene. Contrastingly, a gradual transition to drier conditions at the end of the AHP has been detected in pollen records from lake sedimentary archives from northern Chad (Kröpelin et al., 2008) and northeastern Nigeria (Salzmann et al., 2002). However, neither dust nor pollen data can serve as immediate proxy for aridity itself, but rather reflect responses to changes in the hydrological regime. To test the abruptness of the end of the AHP and unravel late Holocene hydrologic change, we combine compound-specific carbon and hydrogen isotope analyses (δ13C, δD) of plant lipids covering the past 14ka with simulations of water isotope composition in an Earth System Model. We extracted terrestrial biomarkers (long-chain n-alkanes) from the high resolution marine sedimentary core GeoB7920-2 taken in immediate proximity to ODP Site 658C off the Sahara-Sahel transition in NW Africa. Because plants use environmental water (in the Sahel mainly from precipitation) as hydrogen source, changes in the δD signature of the plant-derived biomarkers can be attributed to isotopic changes in rainfall and ultimately to changes in the hydrological cycle on the continent. The n-alkanes show typical terrestrial plant signatures; δ13C values indicate predominance (60-100%) of C4-type plants, i.e., warm-season grasses. δD values of the most abundant n-C31 alkane, vary between -140‰ and -165‰ VSMOW. Generally, the AHP is characterized by lower δD values, indicating more rainfall and humid conditions in NW Africa. Compound-specific plant-wax isotope data from GeoB 7920-2 suggest a gradual transition in continental hydrology at the end of the

  7. The effects of gradually induced backward movement of the mandible by a Twin Inclined Plane Device in rats.

    Science.gov (United States)

    Hua, Xianming; Xiong, Hui; Han, Guangli; Cheng, Xiangrong

    2012-09-01

    To develop a model of gradually induced backward movement of the mandible under normal masticatory action and to examine morphological changes in the mandible and condylar cartilage in rats. The newly developed Twin Inclined Plane Device (TIPD) was composed of upper and lower posterior metal crowns with a long inclined plane on both sides separately and was applied in experimental groups of 6-week-old male Wister rats. After 3, 14, 30, and 60 days, the rats were euthanatized and samples were collected. Various measurements and hematoxylin-and-eosin stains were performed. From day 30 on, the length of the condylar process was shorter in the TIPD groups than in the control groups (P mandibular plane was greater in the TIPD groups (P movement of the mandible under normal masticatory action. TIPD can cause region-specific changes in condylar cartilage and leads to a continuous remodeling.

  8. Bender-Gradual Scoring System (B-SPG: Analysis of the maturation of visual-motor perception of children

    Directory of Open Access Journals (Sweden)

    Lariana Paula Pinto

    2013-12-01

    Full Text Available This study aimed to investigate the maturational aspect of visual motor perception ability, assessed by Bender - Gradual Scoring System (B-SPG in relation to age and educational level. Analyses of variance were made between the total score and the punctuation received on each reproduction of the figures, being compared according to age and educational level. Participants were 361 students, of both genders, between 6 and 10 years, from 1st to 5th years of primary education from public and private schools. The total scores obtained in the test differed significantly in relation to age and educational level. Confirming the proposal of instrument, it became clear that the B-GSP proved to be sensitive to capture the maturational aspect of visual motor perception ability.

  9. 33 CFR 334.1120 - Pacific Ocean in the vicinity of Point Mugu, Calif.; naval small arms firing range.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pacific Ocean in the vicinity of Point Mugu, Calif.; naval small arms firing range. 334.1120 Section 334.1120 Navigation and Navigable... REGULATIONS § 334.1120 Pacific Ocean in the vicinity of Point Mugu, Calif.; naval small arms firing range. (a...

  10. 33 CFR 334.620 - Straits of Florida and Florida Bay in vicinity of Key West, Fla.; operational training area...

    Science.gov (United States)

    2010-07-01

    ... Bay in vicinity of Key West, Fla.; operational training area, aerial gunnery range, and bombing and strafing target areas, Naval Air Station, Key West, Fla. 334.620 Section 334.620 Navigation and Navigable... REGULATIONS § 334.620 Straits of Florida and Florida Bay in vicinity of Key West, Fla.; operational training...

  11. Gradual adaptation to salt and dissolved oxygen: Strategies to minimize adverse effect of salinity on aerobic granular sludge.

    Science.gov (United States)

    Wang, Zhongwei; van Loosdrecht, Mark C M; Saikaly, Pascal E

    2017-11-01

    Salinity can affect the performance of biological wastewater treatment in terms of nutrient removal. The effect of salt on aerobic granular sludge (AGS) process in terms of granulation and nutrient removal was examined in this study. Experiments were conducted to evaluate the effect of salt (15 g/L NaCl) on granule formation and nutrient removal in AGS system started with flocculent sludge and operated at DO of 2.5 mg/L (phase I). In addition, experiments were conducted to evaluate the effect of gradually increasing the salt concentration (2.5 g/L to 15 g/L NaCl) or increasing the DO level (2.5 mg/L to 8 mg/L) on nutrient removal in AGS system started with granular sludge (phase II) taken from an AGS reactor performing well in terms of N and P removal. Although the addition of salt in phase I did not affect the granulation process, it significantly affected nutrient removal due to inhibition of ammonia oxidizing bacteria (AOB) and phosphate accumulating organisms (PAOs). Increasing the DO to 8 mg/L or adapting granules by gradually increasing the salt concentration minimized the adverse effect of salt on nitrification (phase II). However, these strategies were not successful for mitigating the effect of salt on biological phosphorus removal. No nitrite accumulation occurred in all the reactors suggesting that inhibition of biological phosphorus removal was not due to the accumulation of nitrite as previously reported. Also, glycogen accumulating organisms were shown to be more tolerant to salt than PAO II, which was the dominant PAO clade detected in this study. Future studies comparing the salinity tolerance of different PAO clades are needed to further elucidate the effect of salt on PAOs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Gradual adaptation to salt and dissolved oxygen: Strategies to minimize adverse effect of salinity on aerobic granular sludge

    KAUST Repository

    Wang, Zhongwei

    2017-08-13

    Salinity can affect the performance of biological wastewater treatment in terms of nutrient removal. The effect of salt on aerobic granular sludge (AGS) process in terms of granulation and nutrient removal was examined in this study. Experiments were conducted to evaluate the effect of salt (15 g/L NaCl) on granule formation and nutrient removal in AGS system started with flocculent sludge and operated at DO of 2.5 mg/L (phase I). In addition, experiments were conducted to evaluate the effect of gradually increasing the salt concentration (2.5 g/L to 15 g/L NaCl) or increasing the DO level (2.5 mg/L to 8 mg/L) on nutrient removal in AGS system started with granular sludge (phase II) taken from an AGS reactor performing well in terms of N and P removal. Although the addition of salt in phase I did not affect the granulation process, it significantly affected nutrient removal due to inhibition of ammonia oxidizing bacteria (AOB) and phosphate accumulating organisms (PAOs). Increasing the DO to 8 mg/L or adapting granules by gradually increasing the salt concentration minimized the adverse effect of salt on nitrification (phase II). However, these strategies were not successful for mitigating the effect of salt on biological phosphorus removal. No nitrite accumulation occurred in all the reactors suggesting that inhibition of biological phosphorus removal was not due to the accumulation of nitrite as previously reported. Also, glycogen accumulating organisms were shown to be more tolerant to salt than PAO II, which was the dominant PAO clade detected in this study. Future studies comparing the salinity tolerance of different PAO clades are needed to further elucidate the effect of salt on PAOs.

  13. Harmonic hopping, and both punctuated and gradual evolution of acoustic characters in Selasphorus hummingbird tail-feathers.

    Directory of Open Access Journals (Sweden)

    Christopher James Clark

    Full Text Available Models of character evolution often assume a single mode of evolutionary change, such as continuous, or discrete. Here I provide an example in which a character exhibits both types of change. Hummingbirds in the genus Selasphorus produce sound with fluttering tail-feathers during courtship. The ancestral character state within Selasphorus is production of sound with an inner tail-feather, R2, in which the sound usually evolves gradually. Calliope and Allen's Hummingbirds have evolved autapomorphic acoustic mechanisms that involve feather-feather interactions. I develop a source-filter model of these interactions. The 'source' comprises feather(s that are both necessary and sufficient for sound production, and are aerodynamically coupled to neighboring feathers, which act as filters. Filters are unnecessary or insufficient for sound production, but may evolve to become sources. Allen's Hummingbird has evolved to produce sound with two sources, one with feather R3, another frequency-modulated sound with R4, and their interaction frequencies. Allen's R2 retains the ancestral character state, a ∼1 kHz "ghost" fundamental frequency masked by R3, which is revealed when R3 is experimentally removed. In the ancestor to Allen's Hummingbird, the dominant frequency has 'hopped' to the second harmonic without passing through intermediate frequencies. This demonstrates that although the fundamental frequency of a communication sound may usually evolve gradually, occasional jumps from one character state to another can occur in a discrete fashion. Accordingly, mapping acoustic characters on a phylogeny may produce misleading results if the physical mechanism of production is not known.

  14. Effect of gradual or abrupt cessation of milking at dry off on milk yield and somatic cell score in the subsequent lactation.

    Science.gov (United States)

    Gott, P N; Rajala-Schultz, P J; Schuenemann, G M; Proudfoot, K L; Hogan, J S

    2017-03-01

    The objective of this study was to assess the effect of milk cessation method (abrupt or gradual) at dry off on milk yield and somatic cell score (SCS) up to 120 d in milk during the subsequent lactation. Data from 428 cows from 8 dairy herds in Ohio were analyzed. Abrupt cessation cows kept the farm's regular milking schedule (2 or 3 times) through dry off and gradual cessation cows were milked once daily for the final week of lactation. Milk yield and SCS were collected using Dairy Herd Improvement Association test-day records. Aseptic quarter milk samples were collected approximately 1 wk before dry off, at dry off, and within 1 wk after calving for bacterial culture to determine the presence of intramammary infections. Overall, milk cessation method was not significantly associated with either milk yield or SCS in early lactation; however, interaction between the milk cessation method and herd was highly significant. Cows producing greater amounts of milk around dry off had significantly higher SCS in the following lactation. Shorter dry periods were significantly associated with decreased milk yield in the following lactation, especially among abruptly dried off cows. Additionally, as expected, several other factors, such as parity of cows and stage of lactation, were significantly associated with both outcomes. No interactions between the milk cessation method and the other explanatory variables in the final models were significant. The results of the current study suggest that higher milk yield at dry off was associated with higher SCS in the following lactation, even though milk cessation method at the end of lactation had a varying effect on test-day milk yield and SCS in different herds during the first 120 d in milk in the following lactation. The specific herd characteristics influencing this could not be identified within this study, warranting further research. The Authors. Published by the Federation of Animal Science Societies and Elsevier Inc. on

  15. Climatic extreme events combine with impacts of gradual climate change: recent evidence from the Andes and the Alps

    Science.gov (United States)

    Huggel, Christian; Giráldez, Claudia; Haeberli, Wilfried; Schneider, Demian; Frey, Holger; Schaub, Yvonne; Cochachin, Alejo; Portocarrero, Cesar; García, Javier; Guillén Ludeña, Sebastián; Rohrer, Mario; McArdell, Brian

    2013-04-01

    In high-mountain areas climatic extreme events can combine with effects of gradual climate change to form cascading processes, occasionally resulting in major disasters. Heavy precipitation events thereby evolve into mass movement processes such as landslides, avalanches and debris flows that can devastate urban areas at the foot of mountains. The transformation and interaction of processes are complex and often not sufficiently understood or difficult to predict, and thus more research is needed. Of particular concern are landslide impacts into existing or new glacier lakes from destabilized mountain flanks in relation with glacier retreat and permafrost degradation. Here we analyze a number of recent events in the Andes of Peru and compare them with observations in the Alps in Europe. In southern Peru debris flow events that were among the largest recent ones worldwide remained largely unstudied although they destroyed entire towns and important traffic and energy infrastructure. We used a combination of field work, satellite images, satellite rainfall data and available meteorological stations as well as numerical modeling to reconstruct origin, type and effect of these events. Large sediment deposits resulting from deglaciation processes represent a key factor, and were mobilized by heavy rainfall events. Tens of millions of m3 sediment were transported downstream in single events, with compound effects on downstream river systems causing destruction and inundation. Other recent events in Peru underline the importance of a cascade of process interaction, with ice avalanches impacting glacier lakes, triggering flood waves and debris flows that travel downstream and eventually impact urban areas. In the Alps recent observations indicate an increase of occurrence of complex compound processes with short-term climatic events overprinting on longer-term effects of gradual climate change (e.g. from glacier retreat and permafrost degradation). Especially important are

  16. Gradual reappearance of post-hibernation circadian rhythmicity correlates with numbers of vasopressin-containing neurons in the suprachiasmatic nuclei of European ground squirrels

    NARCIS (Netherlands)

    Hut, R.A; van der Zee, E.A; Jansen, K; Gerkema, M.P.; Daan, S.

    European ground squirrels (Spermophilus citellus) in outside enclosures show suppressed circadian rhythmicity in body temperature patterns during the first days of euthermia after hibernation. This may reflect either gradual reappearance of circadian rhythmicity following suppressed functioning of

  17. Characterisation of haematological profiles and whole blood relative gene expression levels in Holstein-Friesian and Jersey bull calves undergoing gradual weaning

    National Research Council Canada - National Science Library

    Johnston, D; Kenny, D A; Kelly, A K; McCabe, M S; McGee, M; Waters, S M; Earley, B

    2016-01-01

    .... The objectives of the study were to examine (i) the effect of breed and plane of nutrition, on haematological profiles of artificially reared Holstein-Friesian and Jersey bull calves in response to gradual weaning, and (ii...

  18. Electric and magnetic field testing in vicinity of 110/x kV substations

    Directory of Open Access Journals (Sweden)

    Grbić Maja

    2016-01-01

    Full Text Available The levels of non-ionizing radiation (electric and magnetic fields at power frequency, which occur near 110/x kV substations are analyzed in this paper. The results of electric field strength and magnetic flux density measurements in the vicinity of three typical substations of the aforementioned voltage level are shown. With the purpose of estimating the exposure of the population to these fields, the obtained results were compared to the reference maximum levels set for increased sensitivity areas, which amount to 2 kV/m for electric field and 40 μT for magnetic flux density. The objective of the conducted analysis is to reach general conclusions on the levels of electric and magnetic fields, which may occur in the vicinity of the substations mentioned above, and evaluate their compliance with the national regulations on the population protection from non-ionizing radiation.

  19. DFT Study of the Molybdenum-Catalyzed Deoxydehydration of Vicinal Diols

    DEFF Research Database (Denmark)

    Lupp, Daniel; Christensen, Niels Johan; Dethlefsen, Johannes Rytter

    2015-01-01

    The mechanism of the molybdenum-catalyzed deoxydehydration (DODH) of vicinal diols has been investigated using density functional theory. The proposed catalytic cycle involves condensation of the diol with an MoVI oxo complex, oxidative cleavage of the diol resulting in an MoIV complex, and extru......The mechanism of the molybdenum-catalyzed deoxydehydration (DODH) of vicinal diols has been investigated using density functional theory. The proposed catalytic cycle involves condensation of the diol with an MoVI oxo complex, oxidative cleavage of the diol resulting in an MoIV complex......, and extrusion of the alkene. We have compared the proposed pathway with several alternatives, and the results have been corroborated by comparison with the molybdenum- catalyzed sulfoxide reduction recently published by Sanz et al. and with experimental observations for the DODH itself. Improved understanding...

  20. Impact of nucleation on step-meandering instabilities during step-flow growth on vicinal surfaces.

    Science.gov (United States)

    Beausoleil, A; Desjardins, P; Rochefort, A

    2014-03-01

    Step-meandering instabilities can manifest during step-flow growth on vicinal surfaces [Bales and Zangwill, Phys. Rev. B 41, 5500 (1990); Pierre-Louis, D'Orsogna, and Einstein, Phys. Rev. Lett. 82, 3661 (1999)]. A phase diagram based on the various growth regimes of a vicinal surface allows us to study the impact of nucleation on these meanders and to predict a meandering instability caused by the nucleation and the coalescence of both islands and steps. Using an accelerated kinetic Monte Carlo method, we find that the coalescence of islands with steps produces large protrusions and deep ripples and that the resulting meandering instability is reinforced by the growth of the islands at almost the same positions from one monolayer to the other. A coarsening phenomenon occurs for the instability wavelength until mounds appear, favored by a large Ehrlich-Schwoebel barrier. Such a meandering instability could be exploited for periodic self-assembly.

  1. Electric and magnetic field testing in vicinity of 110/x kV substations

    OpenAIRE

    Grbić Maja; Pavlović Aleksandar; Hrvić Dejan; Vulević Branislav

    2016-01-01

    The levels of non-ionizing radiation (electric and magnetic fields) at power frequency, which occur near 110/x kV substations are analyzed in this paper. The results of electric field strength and magnetic flux density measurements in the vicinity of three typical substations of the aforementioned voltage level are shown. With the purpose of estimating the exposure of the population to these fields, the obtained results were compared to the reference maximum levels set for increased sensitivi...

  2. Turbulent flow in a ribbed channel: Flow structures in the vicinity of a rib

    DEFF Research Database (Denmark)

    Wang, Lei; Salewski, Mirko; Sundén, Bengt

    2010-01-01

    PIV measurements are performed in a channel with periodic ribs on one wall. The emphasis of this study is to investigate the flow structures in the vicinity of a rib in terms of mean velocities, Reynolds stresses, probability density functions (PDF), and two-point correlations. The PDF distribution......-based visualization is applied to the separation bubble upstream of the rib. Salient critical points and limit cycles are extracted, which gives clues to the physical processes occurring in the flow....

  3. Flow- topography Interactions in the Vicinity of a Deep Ocean Island and a Ridge

    Science.gov (United States)

    2015-09-30

    moored platforms. 2 WORK COMPLETED Attend the FLEAT planning meeting in June 2015 at Scripps Institute of Oceanography. Preliminary deep -mooring...1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Flow-topography Interactions in the Vicinity of a Deep ...located north of Palau covers the submarine ridge, while the second mooring-line coveres deep slopes and the shallow bank just north of Palau (Figure 1

  4. Evaluation of the force generated by gradual deflection of orthodontic wires in conventional metallic, esthetic, and self-ligating brackets

    Directory of Open Access Journals (Sweden)

    Manoela Fávaro Francisconi

    Full Text Available ABSTRACT Objective: The purpose of this study was to evaluate the deflection forces of Nitinol orthodontic wires placed in different types of brackets: metallic, reinforced polycarbonate with metallic slots, sapphire, passive and active self-ligating, by assessing strength values variation according to gradual increase in wire diameter and deflection and comparing different combinations in the different deflections. Material and Methods: Specimens were set in a clinical simulation model and evaluated in a Universal Testing Machine (INSTRON 3342, using the ISO 15841 protocol. Data were subjected to One-way ANOVA, followed by Tukey tests (p<0.05. Results: Self-ligating brackets presented the most similar behavior to each other. For conventional brackets there was no consistent behavior for any of the deflections studied. Conclusions: Self-ligating brackets presented the most consistent and predictable results while conventional brackets, as esthetic brackets, showed very different patterns of forces. Self-ligating brackets showed higher strength in all deflections when compared with the others, in 0.020-inch wires.

  5. Gradual assembly of avian body plan culminated in rapid rates of evolution across the dinosaur-bird transition.

    Science.gov (United States)

    Brusatte, Stephen L; Lloyd, Graeme T; Wang, Steve C; Norell, Mark A

    2014-10-20

    The evolution of birds from theropod dinosaurs was one of the great evolutionary transitions in the history of life. The macroevolutionary tempo and mode of this transition is poorly studied, which is surprising because it may offer key insight into major questions in evolutionary biology, particularly whether the origins of evolutionary novelties or new ecological opportunities are associated with unusually elevated "bursts" of evolution. We present a comprehensive phylogeny placing birds within the context of theropod evolution and quantify rates of morphological evolution and changes in overall morphological disparity across the dinosaur-bird transition. Birds evolved significantly faster than other theropods, but they are indistinguishable from their closest relatives in morphospace. Our results demonstrate that the rise of birds was a complex process: birds are a continuum of millions of years of theropod evolution, and there was no great jump between nonbirds and birds in morphospace, but once the avian body plan was gradually assembled, birds experienced an early burst of rapid anatomical evolution. This suggests that high rates of morphological evolution after the development of a novel body plan may be a common feature of macroevolution, as first hypothesized by G.G. Simpson more than 60 years ago. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. High-grade spondylolisthesis: gradual reduction using Magerl's external fixator followed by circumferential fusion technique and long-term results.

    Science.gov (United States)

    Karampalis, Christos; Grevitt, Michael; Shafafy, Masood; Webb, John

    2012-05-01

    To report the results of a cohort of patients treated with this technique high lighting radiological and functional outcomes, discussing also benefits arising from a gradual reduction procedure compared with other techniques. We evaluated nine patients who have undergone high-grade listhesis reduction and circumferential fusion at our institution from 1988 to 2006. Average length of follow-up was 11 years (5-19). Functional outcomes and radiological measurements were recorded and reported. Slip magnitude was reduced by an average of 2.9 grades (Meyerding classification). Slip angle improved by an average of 66% (p = 0.0001), lumbosacral angle by 47% (p = 0.0002), sacral rotation by 51% (p = 0.0068) and sacral inclination by 47% (p = 0.0055). At the latest follow-up 88.9% had achieved solid fusion. Post-operative 10-point Visual Analogue Score (VAS) for back pain had improved by 70% (p Average postoperative Oswestry Disability Index for all patients was 8% (range 0-16%) and that for Low Back Outcome Scores was 56.6 (range 44-70). All components of Short Form 36 Health Survey were greater than 80%. Overall patients' expectations were met in 100%. This is an effective and safe technique which addresses the lumbosacral kyphosis and cosmetic deformity without the neurological complications which accompany other reduction and fusion techniques for high-grade spondylolisthesis.

  7. Necessity, futility and the possibility of defining life are all embedded in its origin as a punctuated-gradualism.

    Science.gov (United States)

    Popa, Radu

    2010-04-01

    The criteria used for defining life are influenced by various philosophical visions about life, ranging from holism to reductionism and from mechanistic-reductionism to vitalism. Using different scenarios about the origin and evolution of life as well as properties of energy-dissipative systems, artificial life simulations and basic tenets of xenobiology, guidelines can be established for formulating a definition of life. A definition of life is proposed that is parametric, non-Earth-centric, quantitative and capable of discriminating 'living entities' from 'life'. Living entities are defined as self-maintained systems, capable of adaptive evolution individually, collectively or as a line of descend. Life is a broader concept indicating that the capacity to express these attributes is either virtual or actual. At least four major phase transitions can be recognized during the origin of life (reflexive activity; self-regulated homeostasis; the advent of informatons and the origin of adaptive evolution); these make the origin and evolution of early life an example of 'punctuated gradualism'. Such phase transitions can be used to identify a boundary in early evolution where life began. This contribution identifies the step in the evolution of a dynamic system when digital control of the system's state becomes dominant over analogical control, and genetic information is irreversibly used for adaptive evolution, as the boundary between non-living and living systems.

  8. Magnetostrictive hypersound generation by spiral magnets in the vicinity of magnetic field induced phase transition

    Energy Technology Data Exchange (ETDEWEB)

    Bychkov, Igor V. [Chelyabinsk State University, 129 Br. Kashirinykh Str., Chelyabinsk 454001 (Russian Federation); South Ural State University (National Research University), 76 Lenin Prospekt, Chelyabinsk 454080 (Russian Federation); Kuzmin, Dmitry A., E-mail: kuzminda@csu.ru [Chelyabinsk State University, 129 Br. Kashirinykh Str., Chelyabinsk 454001 (Russian Federation); South Ural State University (National Research University), 76 Lenin Prospekt, Chelyabinsk 454080 (Russian Federation); Kamantsev, Alexander P.; Koledov, Victor V.; Shavrov, Vladimir G. [Kotelnikov Institute of Radio-engineering and Electronics of RAS, Mokhovaya Street 11-7, Moscow 125009 (Russian Federation)

    2016-11-01

    In present work we have investigated magnetostrictive ultrasound generation by spiral magnets in the vicinity of magnetic field induced phase transition from spiral to collinear state. We found that such magnets may generate transverse sound waves with the wavelength equal to the spiral period. We have examined two types of spiral magnetic structures: with inhomogeneous exchange and Dzyaloshinskii–Moriya interactions. Frequency of the waves from exchange-caused spiral magnetic structure may reach some THz, while in case of Dzyaloshinskii–Moriya interaction-caused spiral it may reach some GHz. These waves will be emitted like a sound pulses. Amplitude of the waves is strictly depends on the phase transition speed. Some aspects of microwaves to hypersound transformation by spiral magnets in the vicinity of phase transition have been investigated as well. Results of the work may be interesting for investigation of phase transition kinetics as well, as for various hypersound applications. - Highlights: • Magnetostrictive ultrasound generation by spiral magnets at phase transition (PT) is studied. • Spiral magnets during PT may generate transverse sound with wavelength equal to spiral period. • Amplitude of the sound is strictly depends on the phase transition speed. • Microwave-to-sound transformation in the vicinity of PT is investigated as well.

  9. A laboratory-adapted HCV JFH-1 strain is sensitive to neutralization and can gradually escape under the selection pressure of neutralizing human plasma.

    Science.gov (United States)

    Song, Hongshuo; Ren, Furong; Li, Jin; Shi, Shuang; Yan, Ling; Gao, Feng; Li, Kui; Zhuang, Hui

    2012-10-01

    Viral replication and neutralization of hepatitis C viruses (HCV) have been studied using the infectious molecular clone JFH-1. By passaging JFH-1 in hepatoma cells in the absence or presence of HCV neutralizing antibodies (nAbs), we investigated the molecular mechanisms of cell-culture adaptation and sensitivity to nAbs. The cell culture-adapted JFH-1 virus (JFH-1-CA) became more sensitive to nAbs than its parental virus. Sequence analysis revealed that the predominant viruses in the JFH-1-CA population carried two mutations in their envelopes (I414T and V293A). Plasma that could neutralize JFH-1-CA was found in 2 of 7 HCV-infected individuals who have cleared the virus in blood. Plasma 226233 with a higher 50% neutralization titer was used for in vitro selection of neutralization resistant viruses. Under the increasing selection pressure of plasma 226233, the neutralizing sensitivity of JFH-1-CA decreased gradually. Two mutations (T414I and P500S) in envelope were found in all but one sequenced clones in the viral population after eight rounds of selection. Interestingly, the cell-culture adapted mutation I414T reverted back to the wild-type residue (I414) under the selection pressure. By introducing mutations at positions 414 and 500 into the JFH-1 clone, we confirmed that the T414I mutation alone can confer neutralization resistance. The results of this current study suggest that nAbs are present in a subset of HCV-infected individuals who have cleared the virus in blood. Our data also provide the first evidence that, the E2 residue P500, located within a previously identified highly conserved polyclonal epitope, may be a target for neutralizing antibodies present in individual who have spontaneously resolved the HCV infection. Published by Elsevier B.V.

  10. High Temperature Dynamic Response of a Ti-6Al-4V Alloy: A Modified Constitutive Model for Gradual Phase Transformation

    Science.gov (United States)

    Gangireddy, S.; Mates, S. P.

    2017-12-01

    Dynamic deformation behavior of a commercial Ti-6Al-4V alloy is measured between room temperature and beyond the β-transus temperature with high thermal resolution using a rapid-heating Kolsky bar technique. The high thermal resolution allows for a thorough investigation of the dynamic thermal softening behavior of this alloy including effects related to the transformation from the initial hcp α/bcc β dual phase structure to a full β structure for improved modeling of high temperature dynamic manufacturing processes such as high-speed machining. Data are obtained at an average strain rate of 1800 s-1 from room temperature to 1177 °C, with total heating times limited to 3.5 s for all tests. Short heating times prevent thermal distortion of the Kolsky bar loading waves and can allow an investigation of non-equilibrium mechanical behavior, although no such behavior was identified in this study. Between 800 °C and 1000 °C, a progressive change in the thermal softening rate was observed that corresponded well with the equilibrium phase diagram for this alloy. The dynamic thermal softening behavior in the transformation region is incorporated via a new modification of the Johnson-Cook (J-C) viscoplastic constitutive equation. Rate sensitivity is determined at room temperature by combining Kolsky bar data with quasi-static measurements at strain rates from 7.5 × 10-5 s-1 to 0.16 s-1 and the data are fit using multi-parameter optimization to arrive at a full modified J-C model for Ti-6Al-4V to nearly 1200 °C. In its generic form, the modification factor we propose, G( T), is applicable to any material system undergoing gradual phase transformation over a range of temperatures.

  11. Filmes ópticos poliméricos fluorados com índice de refração gradual

    Directory of Open Access Journals (Sweden)

    Bartoli Julio R.

    1999-01-01

    Full Text Available Filmes finos de PMMA foram preparados a partir de solução e expostos ao plasma de CF4+H2, visando mudar o Índice de Refração (I.R. da superficie do PMMA através da fluoração. Os filmes de PMMA expostos ao plasma, denominados de filmes ópticos, foram caracterizados usando as técnicas: ESCA, RBS, FTIR, gravimetria, ângulo de contato, refratometria e elipsometria. Os resultados revelaram que as superfícies de PMMA foram revestidas com uma fina camada de hidrofluorcarbono polimérico, com espessuras variando entre 0,43 e 0,49mim. A camada de hidrofluorcarbono polimérico na superfície do PMMA foi responsável pela significante redução do seu I.R. de 1,49 para 1,43. A concentração de flúor nessa camada aumentou gradualmente em função da profundidade, sendo menor na sua superficie. Como o átomo de flúor é responsável pela redução do I.R., concluiu-se que o I.R. no revestimento fluorado do filme óptico variou também de forma gradual. A técnica de polimerização por plasma de CF4+H2 mostrou-se útil para modificar in situ os I.R. da superfíces de guias de ondas e fibras ópticas poliméricas, visando reduzir as perdas e aumentar a velocidade de transmissão de dados.

  12. Short-term carbon cycling responses of a mature eucalypt woodland to gradual stepwise enrichment of atmospheric CO2 concentration.

    Science.gov (United States)

    Drake, John E; Macdonald, Catriona A; Tjoelker, Mark G; Crous, Kristine Y; Gimeno, Teresa E; Singh, Brajesh K; Reich, Peter B; Anderson, Ian C; Ellsworth, David S

    2016-01-01

    Projections of future climate are highly sensitive to uncertainties regarding carbon (C) uptake and storage by terrestrial ecosystems. The Eucalyptus Free-Air CO2 Enrichment (EucFACE) experiment was established to study the effects of elevated atmospheric CO2 concentrations (eCO2 ) on a native mature eucalypt woodland with low fertility soils in southeast Australia. In contrast to other FACE experiments, the concentration of CO2 at EucFACE was increased gradually in steps above ambient (+0, 30, 60, 90, 120, and 150 ppm CO2 above ambient of ~400 ppm), with each step lasting approximately 5 weeks. This provided a unique opportunity to study the short-term (weeks to months) response of C cycle flux components to eCO2 across a range of CO2 concentrations in an intact ecosystem. Soil CO2 efflux (i.e., soil respiration or Rsoil ) increased in response to initial enrichment (e.g., +30 and +60 ppm CO2 ) but did not continue to increase as the CO2 enrichment was stepped up to higher concentrations. Light-saturated photosynthesis of canopy leaves (Asat ) also showed similar stimulation by elevated CO2 at +60 ppm as at +150 ppm CO2 . The lack of significant effects of eCO2 on soil moisture, microbial biomass, or activity suggests that the increase in Rsoil likely reflected increased root and rhizosphere respiration rather than increased microbial decomposition of soil organic matter. This rapid increase in Rsoil suggests that under eCO2, additional photosynthate was produced, transported belowground, and respired. The consequences of this increased belowground activity and whether it is sustained through time in mature ecosystems under eCO2 are a priority for future research. © 2015 John Wiley & Sons Ltd.

  13. Gradual loss of genetic diversity of Ambrosia artemisiifolia L. populations in the invaded range of central Serbia

    Directory of Open Access Journals (Sweden)

    Kočiš-Tubić Nataša

    2014-01-01

    Full Text Available As an invasive allergenic weed, Ambrosia artemisiifolia L. causes serious public health and economic problems in invaded ranges of Europe. Over the last two decades, while expanding toward southern parts of Serbia, this common ragweed has become a very troublesome plant species in the whole country. Considering the importance of genetic studies in understanding of invasive species, our main objectives in this study were to analyze the genetic diversity and genetic structure of Ambrosia artemisiifolia populations from Central Serbia, a relatively recently invaded region. Comparing values of genetic measures obtained by microsatellite analyses, a number of differences were detected in genetic diversity between sampled populations. Allelic richness-r (ranged from 5.42 to 7.80, the mean number of alleles per locus-NA (5.8-8.4 and the mean number of rare alleles per locus-NR (2.8-5.8 have quite similar ranges across populations. We observed greater genetic variability in populations from the northern part of investigated area than in southern populations. Based on pairwise Fst values, AMOVA results and PCo Analysis, moderate differentiation among population was detected, while the STRUCTURE analysis clearly separated SR-Kru and SR-Les. Data obtained for analyses of differentiation and gradual losses of genetic diversity of sampled populations provides useful information about invasion dynamics of common ragweed in recently invaded region. [Projekat Ministarstva nauke Republike Srbije, br. 173002 and the Secretariat for Science and Tehnological Development, Province of Vojvodina (No. 114-457-2173/2011-01

  14. Digital Geologic Map of Congaree National Park and Vicinity, South Carolina (NPS, GRD, GRI, CONG, CONG digital map)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of Congaree National Park and Vicinity, South Carolina is composed of GIS data layers complete with ArcMap 9.3 layer (.LYR) files, two...

  15. Digital Geologic Map of Bryce Canyon National Park and Vicinity, Utah (NPS, GRD, GRI, BRCA, BRCA digital map)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of Bryce Canyon National Park and Vicinity, Utah is composed of GIS data layers complete with ArcMap 9.3 layer (.LYR) files, two ancillary...

  16. Digital Geologic Map of San Juan Island National Historical Park and vicinity, Washington (NPS, GRD, GRE, SAJH, SAJH digital map)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of San Juan Island National Historical Park and vicinity, Washington is composed of GIS data layers complete with ArcMap 9.2 layer (.LYR)...

  17. Digital Geologic Map of the American Camp Unit and vicinity, Washington (NPS, GRD, GRE, SAJH, SJIS digital map)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of the American Camp Unit and vicinity, Washington is composed of GIS data layers complete with ArcMap 9.2 layer (.LYR) files, two ancillary...

  18. Digital Geologic Map of Palo Alto Battlefield National Historic Site and vicinity, Texas (NPS, GRD, GRE, PAAL, PAAL digital map)

    Data.gov (United States)

    National Park Service, Department of the Interior — The Digital Geologic Map of Palo Alto Battlefield National Historic Site and vicinity, Texas is composed of GIS data layers complete with ArcMap 9.2 layer (.LYR)...

  19. Decreasing incidence rates of bacteremia

    DEFF Research Database (Denmark)

    Nielsen, Stig Lønberg; Pedersen, C; Jensen, T G

    2014-01-01

    ) and the incidence rate of nosocomial bacteremia decreased by 28.9% from 82.2 to 56.0 (4.2% annually, p Staphylococcus aureus (12.3%), coagulase-negative staphylococci (10.......0%) and Streptococcus pneumoniae (9.1%). Regardless of place of acquisition, the proportion of bacteremias caused by enterococci increased (p

  20. Two-dimensional, steady-state model of ground-water flow, Nevada Test Site and vicinity, Nevada-California

    Science.gov (United States)

    Waddell, R.K.

    1982-01-01

    A two-dimensional, steady-state model of ground-water flow beneath the Nevada Test Site and vicinity has been developed using inverse techniques. The area is underlain by clastic and carbonate rocks of Precambrian and Paleozoic age and by volcanic rocks and alluvium of Tertiary and Quaternary age that have been juxtaposed by normal and strike-slip faulting. Aquifers are composed of carbonate and volcanic rocks and alluvium. Characteristics of the flow system are determined by distribution of low-conductivity rocks (barriers); by recharge originating in the Spring Mountains, Pahranagat, Timpahute, and Sheep Ranges, and in Pahute Mesa; and by underflow beneath Pahute Mesa from Gold Flat and Kawich Valley. Discharge areas (Ash Meadows, Oasis Valley, Alkali Flat, and Furnace Creek Ranch) are upgradient from barriers. Sensitivities of simulated hydraulic heads and fluxes to variations in model parameters were calculated to guide field studies and to help estimate errors in predictions from transport modeling. Hydraulic heads and fluxes are very sensitive to variations in the greater magnitude recharge/discharge terms. Transmissivity at a location may not be the most important transmissivity for determining flux there. Transmissivities and geometries of large barriers that impede flow from Pahute Mesa have major effects on fluxes elsewhere; as their transmissivities are decreased, flux beneath western Jackass Flats and Yucca Mountains is increased as water is diverted around the barriers. Fortymile Canyon is underlain by highly transmissive rocks that cause potentiometric contours to vee upgradient; increasing their transmissivity increases flow through them, and decreases it beneath Yucca Mountain. (USGS)

  1. Surrogate Data Generation By Gradual Wavelet Reconstruction (GWR): A General Method with Applications to Simulation, Hypothesis Testing and Uncertainty Analysis

    Science.gov (United States)

    Keylock, C. J.

    2015-12-01

    This presentation will introduce the Gradual Wavelet Reconstruction (GWR) method and highlight the diversity of potential applications of the technique in hydrology, geophysics and beyond. The starting point for the method is the Iterated Amplitude Adjusted Fourier Transform (IAAFT) method introduced nearly twenty years ago by Schreiber and Schmitz (Physical Review Letters, 1996). Given a chosen significance level, α, and a γ = {1,2}-tailed statistical test, if (γ/α) -1 surrogate series have been generated with IAAFT, if the value for a metric of nonlinearity for the original data lies outside the range for the surrogates then a significant difference is deemed to exist (the data are assumed non-linear). GWR generalises this idea, by postulating a continuum from ρ = 0 (phase randomised data) to ρ = 1 (the original data). Thus, given rejection of the null hypothesis using IAAFT surrogates, the question of how nonlinear the data are may be answered for the first time by determining the critical value for ρ. This then opens up other research possibilities including: (1) A method for generating synthetic data with an appropriate degree of nonlinearity; (2) Novel approaches to confidence limits for extreme value problems based on the surrogates in (1); and, (3) The testing of the sensitivity of different metrics for nonlinearity. GWR surrogates are produced in the wavelet domain rather than the Fourier one. The parameter ρ is the total energy of the time series that is fixed in place and not randomised. That is, given a wavelet coefficient, wj,k at scale, j, and position, k, the total wavelet energy is the summation of w2j,k over all scales and positions, Σw2j,k. If all the w2j,k are placed in descending rank order, GWR fixes in place n wavelet coefficients such that the total energy of these coefficients is ρ×Σw2j,k. The other coefficients are randomised such that the fidelity of the wavelet filtering operation is preserved. Because it is a completely

  2. Calbindins decreased after space flight

    Science.gov (United States)

    Sergeev, I. N.; Rhoten, W. B.; Carney, M. D.

    1996-01-01

    Exposure of the body to microgravity during space flight causes a series of well-documented changes in Ca2+ metabolism, yet the cellular and molecular mechanisms leading to these changes are poorly understood. Calbindins, vitamin D-dependent Ca2+ binding proteins, are believed to have a significant role in maintaining cellular Ca2+ homeostasis. In this study, we used biochemical and immunocytochemical approaches to analyze the expression of calbindin-D28k and calbindin-D9k in kidneys, small intestine, and pancreas of rats flown for 9 d aboard the space shuttle. The effects of microgravity on calbindins in rats from space were compared with synchronous Animal Enclosure Module controls, modeled weightlessness animals (tail suspension), and their controls. Exposure to microgravity resulted in a significant and sustained decrease in calbindin-D28k content in the kidney and calbindin-D9k in the small intestine of flight animals, as measured by enzyme-linked immunosorbent assay (ELISA). Modeled weightlessness animals exhibited a similar decrease in calbindins by ELISA. Immunocytochemistry (ICC) in combination with quantitative computer image analysis was used to measure in situ the expression of calbindins in the kidney and the small intestine, and the expression of insulin in pancreas. There was a large decrease of immunoreactivity in renal distal tubular cell-associated calbindin-D28k and in intestinal absorptive cell-associated calbindin-D9k of space flight and modeled weightlessness animals compared with matched controls. No consistent difference in pancreatic insulin immunoreactivity between space flight, modeled weightlessness, and controls was observed. Regression analysis of results obtained by quantitative ICC and ELISA for space flight, modeled weightlessness animals, and their controls demonstrated a significant correlation. These findings after a short-term exposure to microgravity or modeled weightlessness suggest that a decreased expression of calbindins

  3. Concentration of NOX in the vicinity of the power plants Vojany EVO 1 and EVO 2

    Directory of Open Access Journals (Sweden)

    Ján Brehuv

    2006-12-01

    Full Text Available The paper presents a calculation of the maximal concentration of nitrogen oxides in the vicinity of point sources (main chimneys of power plants Vojany EVO1 and EVO2. The wind velocity u10,M (7, at which the concentration on a given place in the surrounding of the pollution source attains a maximal value, is calculated. The relation (8 for a calculation of the place with the maximal concentration for a given class of air stability (Table 1 and 2 and for a given wind velocity is derived. According to equation (3 and Table 3, a thermal capacity of EVO1 and EVO2 is calculated, considering a flat country in the vicinity of the sources (x3 = 0 in relation (1. Subsequently, it is also considered that the wind direction has the direction joining the source and the place of concentration calculation (x2 = 0. The calculations of concentration are performed for the 5th class of air stability. As to this class, favourable conditions for the pollutants dispersion are there. Thus, the maximum concentration is in a relatively small distance from the source with a sharp concentration maximum. As to other classes of the air stability (Table 1 and 2, the maximum concentration is located in larger distances from the source, i.e. about 10 km, as it is considered in Table 4 and 5. The theoretical calculation of NOX concentration in the vicinity of the sources, EVO1 and EVO2, shows (Table 4 and 5 that it does not exceed the allowable limit of 150 µg.m-3.

  4. Atmospheric BTEX concentrations in the vicinity of the crude oil refinery of the Baltic region.

    Science.gov (United States)

    Baltrėnas, Pranas; Baltrėnaitė, Edita; Serevičienė, Vaida; Pereira, Paulo

    2011-11-01

    Among chemical industries, petroleum refineries have been identified as large emitters of a wide variety of pollutants. Benzene, toluene, ethylbenzene, and xylene (BTEX) form an important group of aromatic volatile organic compounds (VOCs) because of their role in the troposphere chemistry and the risk posed to human health. A very large crude oil refinery of the Baltic States (200,000 bbl/day) is situated in the northern, rural part of Lithuania, 10 km from the town of Mažeikiai (Lithuania). The objectives of this study were: (1) to determine of atmospheric levels of BTEX in the region rural and urban parts at the vicinity of the crude oil refinery; and (2) to investigate the effect of meteorological parameters (wind speed, wind direction, temperature, pressure, humidity) on the concentrations measured. The averaged concentration of benzene varied from 2.12 ppbv in the rural areas to 2.75 ppbv in the urban areas where the traffic was determined to be a dominant source of BTEX emissions. Our study showed that concentration of benzene, as strictly regulated air pollutant by EU Directive 2008/50/EC, did not exceed the limit of 5 ppbv in the region in the vicinity of the crude oil refinery during the investigated period. No significant change in air quality in the vicinity of the oil refinery was discovered, however, an impact of the industry on the background air quality was detected. The T/B ratio (0.50-0.81) that was much lower than 2.0, identified other sources of pollution than traffic.

  5. Monitoring the ordering in biomolecular films on vicinal silicon surfaces by reflectance difference/anisotropy spectroscopy

    Science.gov (United States)

    Silaghi, Simona D.; Zahn, Dietrich R. T.

    2006-05-01

    DNA base molecules, adenine, thymine, guanine, and cytosine may be employed as charge transport molecules in biomolecular electronic devices. Their electronic properties are comparable with those of inorganic wide bandgap materials, e.g. GaN with the absorption onset in the near ultra-violet (UV) range. A recent field effect transistor study based on a modified DNA base revealed that the prototype bio-transistor gives rise to a better voltage gain compared to one based on carbon nanotubes (CNTs) [G. Mauricio, P. Visconti, V. Arima, S. D'Amico, A. Biasco, E. D'Amone, R. Cingolani, R. Rinaldi, Nanoletters 3 (2003) 479]. Here, in situ reflectance difference/anisotropy spectroscopy (RDS/RAS) is employed under ultra-high vacuum (UHV) conditions for monitoring the growth of DNA base molecules on vicinal hydrogen passivated Si(1 1 1) surfaces. Such vicinal substrates consisting of steps and terraces may serves as suitable templates for molecular ordering. Indeed, RDS/RAS measurements reveal information about molecular ordering of DNA bases induced by the density of steps on silicon surfaces. All four molecules, however, behave differently on the vicinal substrates. The first transition dipole moments corresponding to adenine and thymine molecules align mainly perpendicular to the step edge direction while for guanine and cytosine they align parallel to this direction, however, only in very thin layers. The RDS/RAS signal of the guanine and cytosine layers with thicknesses above 20 nm saturates due to a loss of ordering at higher coverages. Additionally, time-resolved RDS/RAS measurements at the silicon E 2 (4.25 eV) critical point (CP) demonstrate the sensitivity to the biomolecular/inorganic interface formation.

  6. Contribution to the knowledge of jumping spiders (Araneae: Salticidae from vicinity of Jagodina, Central Serbia

    Directory of Open Access Journals (Sweden)

    Stanković, B.

    2012-09-01

    Full Text Available During last 10 years, based on personal collectings, 21 species from 14 genera of Salticidae (Araneae are recorded from vicinity of Jagodina: Ballus chalybeius, Carrhotus xanthogramma, Evarcha arcuata, Evarcha falcata, Heliophanus auratus, Heliophanus cupreus, Heliophanus flavipes, Heliophanus kochii, Icius hamatus, Icius subinermis, Leptorchestes berolinensis, Macaroeris nidicolens, Marpissa muscosa, Marpissa nivoyi, Mendoza canestrinii, Pellenes tripunctatus, Phintella castriesiana, Phlegra fasciata, Pseudeuophrys erratica, Pseudeuophrys lanigera, Salticus scenicus. All those species are provided with habitat notes and global distribution. New records for the spider fauna of Serbia are Heliophanus kochii (Simon 1868, Icius subinermis (Simon, 1937, Marpissa nivoyi (Lucas, 1846 and Mendoza canestrinii (Ninni, 1868.

  7. Anisotropic Spin-Orbit Coupling and Magnetocrystalline Anisotropy in Vicinal Co Films

    Energy Technology Data Exchange (ETDEWEB)

    Dhesi, Sarnjeet S.; van der Laan, Gerrit; Dudzik, Esther; Shick, Alexander B.

    2001-08-06

    The anisotropy of the spin-orbit interaction, <<{lambda}{sub a}> , in vicinal Co films has been measured using x-ray magnetic linear dichroism (XMLD). A linear increase in <{lambda}{sub a}> with Co step density is found using a new sum rule and represents the first experimental confirmation that XMLD probes the magnetocrystalline anisotropy energy (MAE). X-ray magnetic circular dichroism is used to confirm that the XMLD arises from changes in the local step-edge electronic structure. The XMLD sum rule gives a larger MAE compared to macroscopic values and is discussed with respect to other local probes of the MAE.

  8. Investigation of the conductivity distribution in the vicinity of a cascade volcano

    Energy Technology Data Exchange (ETDEWEB)

    Mozley, E.C.

    1982-11-01

    Magnetotelluric and telluric data were acquired in the vicinity of Mount Hood Oregon as part of a multidisciplinary exploration program to evaluate the geothermal potential of this stratocone volcano. Eleven field components were acquired simultaneously over the frequency band of 50. to .001 hertz. These data consisted of one five component magnetotelluric base site, two sets of two component remote electric field measurements and one set of remote horizontal magnetic field measurements. The data were recorded digitally in the field and processed later using the remote electric and magnetic signals to obtain unbiased tensor impedance and geomagnetic transfer function (tipper) estimates.

  9. Current-phase relations in SIsFS junctions in the vicinity of 0-π transition

    Science.gov (United States)

    Bakurskiy, S. V.; Filippov, V. I.; Ruzhickiy, V. I.; Klenov, N. V.; Soloviev, I. I.; Kupriyanov, M. Yu.; Golubov, A. A.

    2017-03-01

    We consider the current-phase relation (CPR) in Josephson junctions with complex insulator-superconductor-ferromagnetic interlayers in the vicinity of the 0-π transition. We find a strong impact of the second harmonic on the CPR of the junctions. It is shown that the critical current can be kept constant in the region of 0-π transition, while the CPR transforms through multivalued hysteretic states depending on the relative values of tunnel transparency and magnetic thickness. Moreover, the CPR in the transition region has multiple branches with distinct ground states.

  10. Wave-induced nearshore flow patterns in the vicinity of Cochin harbour, India

    Digital Repository Service at National Institute of Oceanography (India)

    PrasannaKumar, S.; Vethamony, P.; Murty, C.S.

    , C. S. Murty Refraction function Wave length Wave period Wave orbital velocity 1 INTRODUCTION The dynamics of sediment movement in the littoral zone is governed primarily by wave-induced currents. Specific knowledge of these currents...) _\\] (2) The wave orbital velocities (Umax) at the lower boundary of the fluid Nearshore flow patterns in the vicinity of Cochin Harbour 115 75 ° &5' 7,6" 76~ 15' -- 10 ° i 15' 300 ec N I -10° :hin leltana ~ntnak~ ;Ranaz 30 Fig. 2. A typical...

  11. Electromagnetic fields in the vicinity of DECT cordless telephones and mobile phones

    Directory of Open Access Journals (Sweden)

    Paweł Mamrot

    2015-12-01

    Full Text Available Background: Mobile telephones belong to the most frequently used personal devices. In their surroundings they produce the electromagnetic field (EMF, in which exposure range there are not only users but also nearby bystanders. The aim of the investigations and EMF measurements in the vicinity of phones was to identify the electric field levels with regard to various working modes. Material and methods: Twelve sets of DECT (digital enhanced cordless telecommunications cordless phones (12 base units and 15 handsets, 21 mobile telephones produced by different manufactures, and 16 smartphones in various applications, (including multimedia in the conditions of daily use in living rooms were measured. Measurements were taken using the point method in predetermined distances of 0.05–1 m from the devices without the presence of users. Results: In the vicinity of DECT cordless phone handsets, electric field strength ranged from 0.26 to 2.30 V/m in the distance of 0.05 m – 0.18–0.26 V/m (1 m. In surroundings of DECT cordless telephones base units the values of EMF were from 1.78–5.44 V/m (0.05 m to 0.19– 0.41 V/m (1 m. In the vicinity of mobile phones working in GSM mode with voice transmission, the electric field strength ranged from 2.34–9.14 V/m (0.05 m to 0.18–0.47 V/m (1 m while in the vicinity of mobile phones working in WCDMA (Wideband Code Division Multiple Access mode the electric field strength ranged from 0.22–1.83 V/m (0.05 m to 0.18–0.20 V/m (1 m. Conclusions: The mean values of the electric field strength for each group of devices, mobile phones and DECT wireless phones sets do not exceed the reference value of 7 V/m, adopted as the limit for general public exposure. Med Pr 2015;66(6:803–814

  12. Relativistic theory for picosecond time transfer in the vicinity of Earth

    Science.gov (United States)

    Petit, G.; Wolf, P.

    1994-01-01

    The problem of light propagation is treated in a geocentric reference system with the goal of ensuring picosecond accuracy for time transfer techniques using electromagnetic signals in the vicinity of the Earth. We give an explicit formula for a one way time transfer, to be applied when the spatial coordinates of the time transfer stations are known in a geocentric reference system rotating with the Earth. This expression is extended, at the same accuracy level of one picosecond, to the special cases of two way and LASSO time transfers via geostationary satellites.

  13. Shell model calculation for Te and Sn isotopes in the vicinity of {sup 100}Sn

    Energy Technology Data Exchange (ETDEWEB)

    Yakhelef, A.; Bouldjedri, A. [Physics Department, Farhat abbas University, Setif (Algeria); Physics Department, Hadj Lakhdar University, Batna (Algeria)

    2012-06-27

    New Shell Model calculations for even-even isotopes {sup 104-108}Sn and {sup 106,108}Te, in the vicinity of {sup 100}Sn have been performed. The calculations have been carried out using the windows version of NuShell-MSU. The two body matrix elements TBMEs of the effective interaction between valence nucleons are obtained from the renormalized two body effective interaction based on G-matrix derived from the CD-bonn nucleon-nucleon potential. The single particle energies of the proton and neutron valence spaces orbitals are defined from the available spectra of lightest odd isotopes of Sb and Sn respectively.

  14. Decreasing Fires in Mediterranean Europe.

    Directory of Open Access Journals (Sweden)

    Marco Turco

    Full Text Available Forest fires are a serious environmental hazard in southern Europe. Quantitative assessment of recent trends in fire statistics is important for assessing the possible shifts induced by climate and other environmental/socioeconomic changes in this area. Here we analyse recent fire trends in Portugal, Spain, southern France, Italy and Greece, building on a homogenized fire database integrating official fire statistics provided by several national/EU agencies. During the period 1985-2011, the total annual burned area (BA displayed a general decreasing trend, with the exception of Portugal, where a heterogeneous signal was found. Considering all countries globally, we found that BA decreased by about 3020 km2 over the 27-year-long study period (i.e. about -66% of the mean historical value. These results are consistent with those obtained on longer time scales when data were available, also yielding predominantly negative trends in Spain and France (1974-2011 and a mixed trend in Portugal (1980-2011. Similar overall results were found for the annual number of fires (NF, which globally decreased by about 12600 in the study period (about -59%, except for Spain where, excluding the provinces along the Mediterranean coast, an upward trend was found for the longer period. We argue that the negative trends can be explained, at least in part, by an increased effort in fire management and prevention after the big fires of the 1980's, while positive trends may be related to recent socioeconomic transformations leading to more hazardous landscape configurations, as well as to the observed warming of recent decades. We stress the importance of fire data homogenization prior to analysis, in order to alleviate spurious effects associated with non-stationarities in the data due to temporal variations in fire detection efforts.

  15. Pb inventory in an ombrotrophic bog decreases over time

    Science.gov (United States)

    Baumann, E.; Jeremiason, J.; Sebestyen, S.

    2016-12-01

    Peat cores were collected from the S2 ombrotrophic bog at the Marcell Experimental Forest (MEF) to determine if the Pb inventory in the bog has decreased over time. Pb concentrations in the outflow of the bog measured from 2009-2016 indicated continued mobilization and export of Pb out of the bog despite dramatic decreases in atmospheric deposition. A seminal study conducted by Urban et al. (1990) from 1981-1983 calculated a mass balance of Pb in the S2 watershed which included a Pb inventory in peat based on the approximate time frame of 1930 to 1983. We collected peat cores in 2016 to compare peat inventories of Pb over the same time range. We found that Pb inventories in the peat have decreased over time, consistent with Pb being mobilized by dissolved organic carbon (DOC) and gradually flushed out of the bog. Since 1983, DOC levels may have increased leading to further Pb mobilization and transport from the bog, but this trend is unclear. In contrast to Pb concentrations in the outflow water, upland runoff and the surface sphagnum moss layer have dramatically lower Pb concentrations compared to 1980s levels indicating fast ecosystem responses to a decrease in Pb inputs in these compartments. However, the deeper peat layers near the water table are responding more slowly to the decrease in Pb inputs and historical Pb inputs continue to be mobilized and transported from the bog. Our results would be applicable to other trace metals, such as Hg, that bind strongly to DOC. For example, a dramatic decrease in Hg deposition would not result in near-term decreases in Hg out of the bog.

  16. A single-centre, randomised study on platelet reactivity after abrupt or gradual discontinuation of long-term clopidogrel therapy in patients after percutaneous coronary intervention.

    Science.gov (United States)

    Nadrowski, Paweł; Syzdół, Marcin; Wańha, Wojciech; Nabiałek, Edyta; Skrzypek, Michał; Góral, Joanna; Siewniak, Maria; Kozakiewicz, Krystyna; Ochała, Andrzej; Tendera, Michał; Wojakowski, Wojciech

    Clinical studies have suggested increased risk of thrombotic events after planned cessation of clopidogrel therapy, due to increased platelet reactivity (platelet rebound); however, in many studies platelet function was not assessed before introducing clopidogrel. Patients who are scheduled to stop clopidogrel therapy, do it abruptly, so a gradual drug cessation might provide a beneficial treatment strategy. To determine whether a clopidogrel discontinuation results in platelet rebound hyperaggregability with increased activity compared to pre-treatment values and to assess whether abrupt or tapering clopidogrel cessation may affect platelet reactivity. Patients with stable coronary artery disease (n = 49), on chronic acetylsalicylic acid treatment, who underwent coronary angiography, and were scheduled for elective percutaneous coronary intervention with stent implantation were en-rolled. Patients were randomised to either a tapering clopidogrel discontinuation during a two-week period (tapering group, n = 25) or abrupt drug cessation (abrupt group, n = 24). After 12 months of dual antiplatelet therapy with clopidogrel and acetylsalicylic acid, we performed three follow-up visits with blood sampling. Platelet aggregation was assessed using a mul-tiple electrode aggregometer at inclusion, at cessation day, and seven and 14 days after complete clopidogrel discontinuation. The primary endpoint was the level of adenosine-diphosphate (ADP)-induced platelet aggregation. We also analysed platelet function in the ASPI test and platelet count as secondary endpoints. In 36 patients included in the main analysis, we found significant differences between the two study groups in the levels of ADP-induced platelet aggregation at days seven and 14 after cessation of clopidogrel (p = 0.004 and p = 0.04, respectively). In the abrupt group, platelet aggregation returned to the values similar to baseline at day seven. There were no significant differences between baseline, seven

  17. Pulsed-laser deposition of vicinal and c-axis oriented high temperature superconducting thin films

    CERN Document Server

    Rössler, R

    2000-01-01

    respect to the temperature, oxygen pressure and laser fluence. (Re,Hg)Ba sub 2 Ca sub ( n-1)Cu sub n O sub x films are synthesized on (001) and vicinal SrTiO sub 3 substrates in a two step process employing pulsed-laser deposition of Hg-free precursor films and Hg-vapour annealing in a sealed quartz tube. The sealed quartz tube technique is described in detail and the thermodynamics and the phase formation are discussed. The influence of the Hg-vapour pressure and the annealing temperature on the film properties are investigated. The influence of Hg-vapour annealing on Bi sub 2 Sr sub 2 CaCu sub 2 O sub x films is described. YBa sub 2 Cu sub 3 O sub x films with thicknesses 20 to 480 nm are deposited on vicinal SrTiO sub 3 substrates (10 degrees tilt angle). Variation of the resistivities and changes in the film morphology depending on film thickness are described. The influence of post-annealing treatments on the film properties is discussed. Pulsed-laser deposition (PLD) of high temperature superconducting ...

  18. Chemistry of spring and well waters on Kilauea Volcano, Hawaii, and vicinity

    Energy Technology Data Exchange (ETDEWEB)

    Janik, C.J.; Nathenson, M.; Scholl, M.A.

    1994-12-31

    Published and new data for chemical and isotopic samples from wells and springs on Kilauea Volcano and vicinity are presented. These data are used to understand processes that determine the chemistry of dilute meteoric water, mixtures with sea water, and thermal water. Data for well and spring samples of non-thermal water indicate that mixing with sea water and dissolution of rock from weathering are the major processes that determine the composition of dissolved constituents in water. Data from coastal springs demonstrate that there is a large thermal system south of the lower east rift of Kilauea. Samples of thermal water from shallow wells in the lower east rift and vicinity have rather variable chemistry indicating that a number of processes operate in the near surface. Water sampled from the available deep wells is different in composition from the shallow thermal water, indicating that generally there is not a significant component of deep water in the shallow wells. Data for samples from available deep wells show significant gradients in chemistry and steam content of the reservoir fluid. These gradients are interpreted to indicate that the reservoir tapped by the existing wells is an evolving vapor-dominated system.

  19. Mapping human vulnerability to chemical accidents in the vicinity of chemical industry parks.

    Science.gov (United States)

    Li, Fengying; Bi, Jun; Huang, Lei; Qu, Changsheng; Yang, Jie; Bu, Quanmin

    2010-07-15

    China is suffering from severe pollution accidents which may have catastrophic impacts on the local population and environment. Some questions are unclear to local governments and industry operators like "who are vulnerable to the chemical risks?" and "what is the magnitude of vulnerability?". This paper concentrates on exploring the concepts of human vulnerability and the methodology of analyzing human vulnerability to chemical accidents in the vicinity of chemical industry parks. A conceptual model of human vulnerability to chemical accidents is developed, revealing the roots of human vulnerability and emphasizing its role in risk management. A geographical information system (GIS)-based methodology for mapping vulnerability is proposed and applied to the Nanjing Chemical Industry Park in China. By combining physical vulnerability and social vulnerability spatially, the total vulnerability is revealed to better respond to accidents. It is proposed to improve traffic lines and allocation of medical services, and include vulnerability assessment in land-use planning to reduce future risks. In other words, it seems feasible and effective to reveal physical, social and total vulnerability of residents in the vicinity of chemical risk sources. 2010 Elsevier B.V. All rights reserved.

  20. Neutron diffraction analysis of residual strain/stress distribution in the vicinity of high strength welds

    Directory of Open Access Journals (Sweden)

    Hamák I.

    2010-06-01

    Full Text Available Residual stresses resulting from non homogeneous heat distribution during welding process belong to most significant factor influencing behavior of welded structures. These stresses are responsible for defect occurrence during welding and they are also responsible for crack initiation and propagation at the either static or dynamic load. The significant effect of weld metal chemical composition as well as the effect of fatigue load and local plastic deformation on residual stress distribution and fatigue life have been recognized for high strength steels welds. The changes in residual stress distribution have then positive effect on cold cracking behavior and also on fatigue properties of the welds [1-3]. Several experimental methods, both destructive and non-destructive, such as hole drilling method, X-ray diffraction, neutron diffraction and others, have been used to examine residual stress distribution in all three significant orientations in the vicinity of the welds. The present contribution summarizes the results of neutron diffraction measurements of residual stress distribution in the vicinity of single-pass high-strength-steel welds having different chemical composition as well as the influence of fatigue load and local plastic deformation. It has been observed that the chemical composition of the weld metal has a significant influence on the stress distribution around the weld. Similarly, by aplying both cyclic load or pre-stress load on the specimens, stress relaxation was observed even in the region of approximately 40 mm far from the weld toe.

  1. Local temperature measurement in the vicinity of electromagnetically heated magnetite and gold nanoparticles

    Science.gov (United States)

    Gupta, Amit; Kane, Ravi S.; Borca-Tasciuc, Diana-Andra

    2010-09-01

    This paper describes a new technique employing fluorescent quantum dots as temperature probes for measuring the temperature rise in the proximity of nanoparticles heated by a radio frequency (rf) electromagnetic field. The remote heating of nanoparticles by an rf field is a promising approach to control biological transformations at the molecular level. In principle, the heat dissipated by each nanoparticle might produce a temperature increase in its proximity, facilitating a change in the molecules directly attached to it but not in the others. Although this method has been demonstrated to provide control over biological transformations, the proposed mechanism involves producing and maintaining large temperature differences across small distances, in the range of several degrees Celsius across tens of nanometers. Existing theories for heat generation and transfer in rf heated nanoparticle systems cannot account for these gradients. To better understand the limitations of local heating, the temperature in the vicinity of rf heated nanoparticles was measured. Dilute aqueous suspensions of gold and magnetite nanoparticles were remotely heated by an rf field between 600-800 kHz. Two systems were investigated: a control sample consisting of quantum dots mixed with nanoparticles and a solution of quantum dots covalently linked to nanoparticles. The temperature of the fluorescent probes represents the average temperature in the former and the local temperature in the later. For the experimental conditions employed in this study, the measured temperature rise in the vicinity of rf heated nanoparticles were similar to the average or "bulk" temperature, in agreement with theoretical predictions.

  2. Group V adsorbate structures on vicinal Ge(001) surfaces determined from the optical spectrum

    Science.gov (United States)

    Banerjee, S.; Patterson, C. H.; McGilp, J. F.

    2017-06-01

    Vicinal Ge(001) is the standard substrate for the fabrication of high-performance solar cells by metal-organic vapour phase epitaxy, where growth of the III-V material on single domain Ge surfaces, with a single dimer orientation, minimizes the formation of anti-phase domain defects. Reflectance anisotropy spectroscopy has proved to be a powerful and sensitive optical probe of such anisotropic surface structures, but moving beyond fingerprinting to atomic structure determination from the optical spectra has been held back by the high computational cost. It is shown that an empirical, local-orbital-based hybrid density functional theory approach produces very good agreement between the theory and the experiment for (2 × 1)-As and (2 × 1)-Sb structures grown on vicinal Ge(001). These results, when taken together with previous work on Si interfaces, show that this computationally efficient approach is likely to prove to be an important general technique for determining the structure of anisotropic semiconductor surfaces and interfaces by comparing the experimental and calculated optical spectrum.

  3. Nanoscale patterning, macroscopic reconstruction, and enhanced surface stress by organic adsorption on vicinal surfaces

    Science.gov (United States)

    Pollinger, Florian; Schmitt, Stefan; Sander, Dirk; Tian, Zhen; Kirschner, Jürgen; Vrdoljak, Pavo; Stadler, Christoph; Maier, Florian; Marchetto, Helder; Schmidt, Thomas; Schöll, Achim; Umbach, Eberhard

    2017-01-01

    Self-organization is a promising method within the framework of bottom-up architectures to generate nanostructures in an efficient way. The present work demonstrates that self-organization on the length scale of a few to several tens of nanometers can be achieved by a proper combination of a large (organic) molecule and a vicinal metal surface if the local bonding of the molecule on steps is significantly stronger than that on low-index surfaces. In this case thermal annealing may lead to large mass transport of the subjacent substrate atoms such that nanometer-wide and micrometer-long molecular stripes or other patterns are being formed on high-index planes. The formation of these patterns can be controlled by the initial surface orientation and adsorbate coverage. The patterns arrange self-organized in regular arrays by repulsive mechanical interactions over long distances accompanied by a significant enhancement of surface stress. We demonstrate this effect using the planar organic molecule PTCDA as adsorbate and Ag(10 8 7) and Ag(775) surfaces as substrate. The patterns are directly observed by STM, the formation of vicinal surfaces is monitored by high-resolution electron diffraction, the microscopic surface morphology changes are followed by spectro-microscopy, and the macroscopic changes of surface stress are measured by a cantilever bending method. The in situ combination of these complementary techniques provides compelling evidence for elastic interaction and a significant stress contribution to long-range order and nanopattern formation.

  4. Scanning Tunneling Microscopy Study of a Vicinal Anatase TiO2 Surface

    Science.gov (United States)

    Li, Shao-Chun; Dulub, Olga; Diebold, Ulrike

    2009-03-01

    Titanium dioxide finds versatile applications in various technical fields including gas sensing, coatings, pigments, heterogeneous catalysis, photocatalytic degradation of pollutants, and solar cells. TiO2 is found in three main crystallographic phases: rutile, anatase and brookite. Rutile is the thermodynamically most stable form and is considered a model system for basic research. However, anatase TiO2 is often considered to be catalytically more active than rutile for reasons not yet completely understood. In this work, using scanning tunneling microscopy (STM) and low energy electron diffraction (LEED), the structure of the anatase TiO2(5 14) surface, ˜10 vicinal to the -- lowest energy -- (101) plane, has been studied. The surface was found to facet into a structure composed of ridges with a uniform width of 5 lattice units. Based on atomically-resolved STM and electron counting rules, it is proposed that the sides of the ridges are parallel to (1 10) and (112) planes. These sides might be reconstructed to stabilize the microfaceted structure. Vapor-deposited gold shows pronounced clustering between the ridges, indicating a one-dimensional template effect of the vicinal surface, which supports denser and more uniformly sized Au clusters, as compared to the flat (101) surface.

  5. Localization of the electromagnetic field in the vicinity of gold nanoparticles: Surface modification of different substrates

    Energy Technology Data Exchange (ETDEWEB)

    Atanasov, Petar A. [Institute of Electronics, Bulgarian Academy of Sciences, Tzarigradsko Shousse 72, Sofia 1784 (Bulgaria)], E-mail: paatanas@ie.bas.bg; Nedyalkov, Nikolay N. [Department of Electronics and Electrical Engineering, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522 (Japan); Institute of Electronics, Bulgarian Academy of Sciences, Tzarigradsko Shousse 72, Sofia 1784 (Bulgaria); Sakai, Tetsuo; Obara, Minoru [Department of Electronics and Electrical Engineering, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522 (Japan)

    2007-12-15

    Theoretical predictions and experimental results for nanosized modification of metal (Au), semiconductor (Si), or dielectric (soda lime glass) substrates using near-electromagnetic field enhancement in the vicinity of gold nanoparticles are presented. The near field properties for the system consisting of an isolated gold nanoparticle or nanoparticle aggregate deposited on the substrates, which is irradiated by electromagnetic wave, are investigated using Finite Difference Time Domain Simulation technique. The influence of the substrate material on the near field distribution characteristics is predicted. The results reveal that the field on the substrate surface is enhanced in the three investigated cases, but its spatial distribution and magnitude depend on the substrate material. In the case of the metal and semiconductor substrate the enhanced near field is strongly localized in the vicinity of the contact point with the particle, in an area with diameter smaller than the particle's one. The intensity of the enhanced field on the glass is more than an order of magnitude lower than the case of using silicon substrate. The properties of the near field on the substrate surface also depend on the particle arrangement. For a two-dimensional gold nanoparticle array, when the particles are closely arrayed, the intensity of the enhanced field on the substrate surface is minimal. With the increase of the interparticle distance the near field intensity increases. The validity of the obtained theoretical results is confirmed experimentally.

  6. Hyperhomocysteinemia decreases bone blood flow

    Directory of Open Access Journals (Sweden)

    Neetu T

    2011-01-01

    Full Text Available Neetu Tyagi*, Thomas P Vacek*, John T Fleming, Jonathan C Vacek, Suresh C TyagiDepartment of Physiology and Biophysics, School of Medicine, University of Louisville, Louisville, KY, USA *These authors have equal authorshipAbstract: Elevated plasma levels of homocysteine (Hcy, known as hyperhomocysteinemia (HHcy, are associated with osteoporosis. A decrease in bone blood flow is a potential cause of compromised bone mechanical properties. Therefore, we hypothesized that HHcy decreases bone blood flow and biomechanical properties. To test this hypothesis, male Sprague–Dawley rats were treated with Hcy (0.67 g/L in drinking water for 8 weeks. Age-matched rats served as controls. At the end of the treatment period, the rats were anesthetized. Blood samples were collected from experimental or control rats. Biochemical turnover markers (body weight, Hcy, vitamin B12, and folate were measured. Systolic blood pressure was measured from the right carotid artery. Tibia blood flow was measured by laser Doppler flow probe. The results indicated that Hcy levels were significantly higher in the Hcy-treated group than in control rats, whereas vitamin B12 levels were lower in the Hcy-treated group compared with control rats. There was no significant difference in folate concentration and blood pressure in Hcy-treated versus control rats. The tibial blood flow index of the control group was significantly higher (0.78 ± 0.09 flow unit compared with the Hcy-treated group (0.51 ± 0.09. The tibial mass was 1.1 ± 0.1 g in the control group and 0.9 ± 0.1 in the Hcy-treated group. The tibia bone density was unchanged in Hcy-treated rats. These results suggest that Hcy causes a reduction in bone blood flow, which contributes to compromised bone biomechanical properties.Keywords: homocysteine, tibia, bone density

  7. Effects of long-term irrigation with treated wastewater on soil quality, soil-borne pathogens, and living organisms: case study of the vicinity of El Hajeb (Tunisia).

    Science.gov (United States)

    Hentati, Olfa; Chaker, Sana; Wali, Ahmed; Ayoub, Tarek; Ksibi, Mohamed

    2014-05-01

    Medium (i.e. 15 years) and long-term (i.e. 20 years) impact of irrigation using secondary-treated municipal wastewater (TWW) was assessed on two agricultural soil samples, denoted by E and G, respectively, in the vicinity of El Hajeb region (Southern Tunisia). Soil pH, electrical conductivity particle size grading, potential risk of salinity, water holding capacity and chemical composition, as well as organic matter content, pathogenic microorganisms and heavy metal concentrations in the TWW-irrigated (E and G) and rainwater-irrigated (T) soils at various depths, were monitored and compared during a 5-year experiment. Our study showed that bacterial abundance is higher in sandy-clayey soil, which has an enhanced ability to retain moisture and nutrients. The high level of bacterial flora in TWW-irrigated soils was significantly (p < 0.05) correlated (r = ~0.5) with the high level of OM. Avoidance assays have been used to assess toxic effects generated by hazards in soils. The earthworms gradually avoided the soils from the surface (20 cm) to the depth (60 cm) of the G transect and then the E transect, preferring the T transect. The same behaviour was observed for springtails, but they seem to be less sensitive to the living conditions in transects G and E than the earthworms. The avoidance response test of Eisenia andrei was statistically correlated with soil layers at the sampling sites. However, the avoidance response test of Folsomia candida was positively correlated with silt-clay content (+0.744*) and was negatively correlated with sand content (-0.744*).

  8. Assessment of the attenuation of an intra-abdominal vein by use of a silicone-polyacrylic acid gradual venous occlusion device in dogs and cats.

    Science.gov (United States)

    Wallace, Mandy L; Ellison, Gary W; Giglio, Robson F; Batich, Christopher D; Berry, Clifford R; Case, J Brad; Kim, Stanley E

    2016-06-01

    OBJECTIVE To evaluate the closure rate and completeness of closure for a silicone-polyacrylic acid gradual venous occlusion device placed around an intra-abdominal vein to simulate gradual occlusion of an extrahepatic portosystemic shunt. ANIMALS 3 purpose-bred cats and 2 purpose-bred dogs. PROCEDURES The device was surgically placed around an external (cats) or internal (dogs) iliac vein. Computed tomographic angiography was performed at the time of surgery and 2, 4, and 6 weeks after surgery. Ultrasonographic examinations of blood flow through the vein within the device were performed at the time of surgery and at weekly intervals thereafter. Dogs were euthanized 6 weeks after surgery, and the external iliac veins were harvested for histologic examination. RESULTS The prototype gradual venous occlusion device was successfully placed in all animals, and all animals recovered without complications following the placement procedure. The vessel was completely occluded in 2 cats by 6 weeks after surgery, as determined on the basis of results of CT and ultrasonography; there was incomplete occlusion with a luminal diameter of 1.5 mm in the other cat by 6 weeks after surgery. The vessel was completely occluded in both dogs by 6 weeks after surgery. Histologic examination of the external iliac veins obtained from the dogs revealed minimal inflammation of the vessel wall and no thrombus formation. CONCLUSIONS AND CLINICAL RELEVANCE The prototype device induced gradual attenuation of an intra-abdominal vessel over a 6-week period. This device may provide another option for gradual occlusion of extrahepatic portosystemic shunts.

  9. Lead and cadmium in mushrooms from the vicinity of two large emission sources in Slovenia

    Energy Technology Data Exchange (ETDEWEB)

    Petkovšek, Samar Al Sayegh, E-mail: samar.petkovsek@erico.si; Pokorny, Boštjan

    2013-01-15

    Cd and Pb contents were determined in 699 samples of fruiting bodies of 55 mushrooms species, collected in the period 2000–2007 in the vicinity of the largest Slovenian thermal power plant (the Šalek Valley) and near an abandoned lead smelter (the Upper Meža Valley). The present study is the first regarding lead and cadmium in mushrooms from those exposed areas. Therefore, there was a significant lack of prior data. Among 55 studied mushroom species 36 species are edible and important from an ecotoxicological perspective. However, the remaining non-edible species are important for bioindication and allowed us to compare our results with other studies carried out in other polluted areas in Europe. The highest contents of Cd were found in Agaricus arvensis Schff.: Fr. (117 mg/kg dw) and Agaricus silvicola L.: Fr. (67.9 mg/kg dw), while the highest contents of Pb were found in Macrolepiota procera (Scop.) Singer (53.8 mg/kg dw) and Lycoperdon perlatum Pers. (50 mg/kg dw), respectively. Considering the high contents of both metals in fruiting bodies of edible fungi, together with FAO/WHO directives on tolerable levels of weekly intake of Pb/Cd by humans, it is evident that consumption of some mushroom species originating from both study areas may pose a significant human health risk. A. arvensis Schff.: Fr., A. silvicola L.: Fr. and Cortinarius caperatus (Pers.) Fr. originating from the Šalek Valley, and Armillaria mellea Vahl. P. Kumm., Boletus edulis Bull., L. perlatum Pers., Leccinum versipelle (Fr. and Hök) Snell, and M. procera (Scop.) Singer originating from the Upper Meža Valley should not be consumed at all. Our findings are consistent with some other studies, which emphasized that mushrooms from heavily polluted areas, such as in the vicinity of smelters, accumulate extremely high amounts of metals, and should therefore be omitted from human consumption. - Highlights: ► The Pb contents were higher in saprophytic fungi in comparison with mycorrhizal

  10. EISCAT and Cluster observations in the vicinity of the dynamical polar cap boundary

    Directory of Open Access Journals (Sweden)

    A. T. Aikio

    2008-02-01

    Full Text Available The dynamics of the polar cap boundary and auroral oval in the nightside ionosphere are studied during late expansion and recovery of a substorm from the region between Tromsø (66.6° cgmLat and Longyearbyen (75.2° cgmLat on 27 February 2004 by using the coordinated EISCAT incoherent scatter radar, MIRACLE magnetometer and Cluster satellite measurements. During the late substorm expansion/early recovery phase, the polar cap boundary (PCB made zig-zag-type motion with amplitude of 2.5° cgmLat and period of about 30 min near magnetic midnight. We suggest that the poleward motions of the PCB were produced by bursts of enhanced reconnection at the near-Earth neutral line (NENL. The subsequent equatorward motions of the PCB would then represent the recovery of the merging line towards the equilibrium state (Cowley and Lockwood, 1992. The observed bursts of enhanced westward electrojet just equatorward of the polar cap boundary during poleward expansions were produced plausibly by particles accelerated in the vicinity of the neutral line and thus lend evidence to the Cowley-Lockwood paradigm. During the substorm recovery phase, the footpoints of the Cluster satellites at a geocentric distance of 4.4 RE mapped in the vicinity of EISCAT measurements. Cluster data indicate that outflow of H+ and O+ ions took place within the plasma sheet boundary layer (PSBL as noted in some earlier studies as well. We show that in this case the PSBL corresponded to a region of enhanced electron temperature in the ionospheric F region. It is suggested that the ion outflow originates from the F region as a result of increased ambipolar diffusion. At higher altitudes, the ions could be further energized by waves, which at Cluster altitudes were observed as BBELF (broad band extra low frequency fluctuations. The four-satellite configuration of Cluster revealed a sudden poleward expansion of the PSBL by 2° during ~5 min. The beginning of the poleward motion of the PCB

  11. EISCAT and Cluster observations in the vicinity of the dynamical polar cap boundary

    Directory of Open Access Journals (Sweden)

    A. T. Aikio

    2008-02-01

    Full Text Available The dynamics of the polar cap boundary and auroral oval in the nightside ionosphere are studied during late expansion and recovery of a substorm from the region between Tromsø (66.6° cgmLat and Longyearbyen (75.2° cgmLat on 27 February 2004 by using the coordinated EISCAT incoherent scatter radar, MIRACLE magnetometer and Cluster satellite measurements. During the late substorm expansion/early recovery phase, the polar cap boundary (PCB made zig-zag-type motion with amplitude of 2.5° cgmLat and period of about 30 min near magnetic midnight. We suggest that the poleward motions of the PCB were produced by bursts of enhanced reconnection at the near-Earth neutral line (NENL. The subsequent equatorward motions of the PCB would then represent the recovery of the merging line towards the equilibrium state (Cowley and Lockwood, 1992. The observed bursts of enhanced westward electrojet just equatorward of the polar cap boundary during poleward expansions were produced plausibly by particles accelerated in the vicinity of the neutral line and thus lend evidence to the Cowley-Lockwood paradigm.

    During the substorm recovery phase, the footpoints of the Cluster satellites at a geocentric distance of 4.4 RE mapped in the vicinity of EISCAT measurements. Cluster data indicate that outflow of H+ and O+ ions took place within the plasma sheet boundary layer (PSBL as noted in some earlier studies as well. We show that in this case the PSBL corresponded to a region of enhanced electron temperature in the ionospheric F region. It is suggested that the ion outflow originates from the F region as a result of increased ambipolar diffusion. At higher altitudes, the ions could be further energized by waves, which at Cluster altitudes were observed as BBELF (broad band extra low frequency fluctuations.

    The four-satellite configuration of Cluster revealed a sudden poleward expansion of the PSBL by 2° during

  12. Laboratory modelling of resonant wave-current interaction in the vicinity wind farm masts

    Science.gov (United States)

    Gunnoo, Hans; Abcha, Nizar; Garcia-Hermosa, Maria-Isabel; Ezersky, Alexander

    2015-04-01

    In the nearest future, by 2020, about 4% of electricity in Europe will be supplied by sea stations operating from renewable sources: ocean thermal energy, wave and tidal energy, wind farms. By now the wind stations located in the coastal zone, provide the most part of electricity in different European countries. Meanwhile, effects of wind farms on the environment are not sufficiently studied. We report results of laboratory simulations aimed at investigation of hydrodynamic fields arising in the vicinity of wind farm masts under the action of currents and surface waves. The main attention is paid to modeling the resonance effects when the amplitude of velocity pulsations in the vicinity of the masts under the joint action of currents and harmonic waves demonstrate significant growth. This resonance can lead to an increase in Reynolds stress on the bottom, intensification of sediment transport and sound generation. The experiments are performed in the 17 meters hydrodynamical channel of laboratory Morphodynamique Continentale et Côtière UMR CNRS 6143. Mast are modeled by vertical cylinder placed in a steady flow. Behind the cylinder turbulent Karman vortex street occurs. Results are obtained in interval of Reynolds numbers Re=103 - 104(Re=Ud/v, where U is the velocity of the flow, d is diameter of the cylinder, ν is cinematic viscosity). Harmonic surface waves of small amplitude propagating upstream are excited by computer controlled wave maker. In the absence of surface waves, turbulent Karman street with averaged frequency f is observed. It is revealed experimentally that harmonic surface waves with a frequencies closed to 2f can synchronize vortex shedding and increase the amplitude of velocity fluctuations in the wake of the cylinder. Map of regimes is found on the parameter plane amplitude of the surface wave - wave frequency. In order to distinguish the synchronization regimes, we defined phase of oscillations using the Hilbert transform technique. We

  13. Simulated effects of groundwater withdrawals from aquifers in Ocean County and vicinity, New Jersey

    Science.gov (United States)

    Cauller, Stephen J.; Voronin, Lois M.; Chepiga, Mary M.

    2016-10-21

    Rapid population growth since the 1930s in Ocean County and vicinity, New Jersey, has placed increasing demands upon the area’s freshwater resources. To examine effects of groundwater withdrawals, a three-dimensional groundwater-flow model was developed to simulate the groundwater-flow systems of five area aquifers: the unconfined Kirkwood-Cohansey aquifer system and Vincentown aquifer, and three confined aquifers— the Rio Grande water-bearing zone, the Atlantic City 800-foot sand, and the Piney Point aquifer. The influence of withdrawals is evaluated by using transient groundwater-flow model simulations that incorporate three withdrawal schemes. These are (1) no-withdrawal conditions; (2) 2000–03 withdrawal conditions, using reported monthly withdrawals at all production wells from January 2000 through December 2003; and (3) maximum-allocation withdrawal conditions using the maximum withdrawal allowed by New Jersey Department of Environmental Protection permits at each well. Particle tracking analysis, using results from model simulations, delineated particle flow paths from production wells to the point of recharge, and estimated particle travel times.Compared with no-withdrawal conditions, 2000–03 withdrawal conditions reduced the amount of groundwater flow out of the Kirkwood-Cohansey aquifer system into streams, increased the net flow of water into other layers, reduced net flow into or out of storage, and reduced flow from the Kirkwood-Cohansey aquifer system to constant head cells.Freshwater discharging to the Barnegat Bay-Little Egg Harbor estuary from streams and groundwater is essential to maintaining the ecology of the bay. Examination of selected stress periods indicates that simulated base flow in streams flowing into the Barnegat Bay-Little Egg Harbor estuary is reduced by as much as 49 cubic feet per second for 2000 to 2003 withdrawal conditions when compared with no-withdrawal conditions.In the three confined aquifers, water levels during

  14. Microphotoluminescence spectroscopy of CdSe quantum dots grown on vicinal-surface and exact-orientation substrates

    Energy Technology Data Exchange (ETDEWEB)

    Makino, T.; Andre, R.; Romestain, R.; Dang, Le Si [CEA-CNRS-UJF Joint Group Nanophysics and Semiconductors (France); Laboratoire de Spectrometrie Physique, CNRS UMR 5588, Universite J. Fourier-Grenoble 1, 38402 Saint-Martin-d' Heres (France); Gerard, J.M. [CEA-CNRS-UJF Joint Group Nanophysics and Semiconductors (France); CEA-Grenoble, Departement de Recherche Fondamentale sur la Matiere Condensee/SP2M, 17 avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Bartels, M.; Lischka, K.; Schikora, D. [Department of Physics, University of Paderborn, Warburger Strasse 100, 33098 Paderborn (Germany)

    2004-03-01

    We investigated the optical properties of CdSe quantum dots (QDs) grown by molecular-beam epitaxy on GaAs substrates using micro-photoluminescence spectroscopy. Comparison was made between the QDs grown on a substrate with a vicinal tilt of 2 in the [111] direction and those on an on-axis substrate. We have studied the evolution of lineshapes of QD photoluminescence spectra under the improved condition of spatial resolution. It was found that the use of a substrate with the vicinal surface leads to the suppression of excitonic PL emitted from a wetting layer. The PL studies revealed that the thermo-stability up to 150 K was obtained in the sample on the on-axis substrate, whereas rapid temperature-induced quenching starting from 6 K was observed in that grown on the vicinal substrate. (copyright 2004 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  15. Microphotoluminescence spectroscopy of CdSe quantum dots grown on vicinal-surface and exact-orientation substrates

    Science.gov (United States)

    Makino, T.; André, R.; Gérard, J. M.; Romestain, R.; Dang, Le Si; Bartels, M.; Lischka, K.; Schikora, D.

    2004-03-01

    We investigated the optical properties of CdSe quantum dots (QDs) grown by molecular-beam epitaxy on GaAs substrates using micro-photoluminescence spectroscopy. Comparison was made between the QDs grown on a substrate with a vicinal tilt of 2° in the [111] direction and those on an on-axis substrate. We have studied the evolution of lineshapes of QD photoluminescence spectra under the improved condition of spatial resolution. It was found that the use of a substrate with the vicinal surface leads to the suppression of excitonic PL emitted from a wetting layer. The PL studies revealed that the thermo-stability up to 150 K was obtained in the sample on the on-axis substrate, whereas rapid temperature-induced quenching starting from 6 K was observed in that grown on the vicinal substrate.

  16. Characteristics of ageostrophic flow in the vicinity of a severe weather outbreak - AVE-SESAME I

    Science.gov (United States)

    Arnold, J. E.

    1982-01-01

    GOES satellite data was used to examine the ageostrophic flow in the vicinity of severe weather outbreaks along the Red River between Texas and Oklahoma in April 1979. The observations were part of the NASA AVE-SESAME I data on atmospheric states close to severe weather conditions. The Barnes Objective Analysis Technique was employed to analyze the data on a 100 km grid. The ageostrophic wind was defined on a regional scale from satellite data on different levels of cloud wind vectors, with a height change signalling a short-wave system in a long-wave trough. The percentage of deviation of the subgeostrophic winds from the geostrophic wind was calculated, and maximum departure corresponded with the region of greatest storm development. Time cross sections of additions to the ageostrophic flow were made as a function of pressure at 100 mb intervals from 900-100 mb. The ageostrophic acceleration was consistently twice the geostrophic acceleration.

  17. New evidence for prehistoric copper metallurgy in the vicinity of Bor

    Directory of Open Access Journals (Sweden)

    Kapuran Aleksandar

    2016-01-01

    Full Text Available The last three years of archaeological investigations at the site Ru`ana in Banjsko Polje, in the immediate vicinity of Bor, have provided new evidence regarding the role of non-ferrous metallurgy in the economy of the prehistoric communities of north-eastern Serbia. The remains of metallurgical furnaces and a large amount of metallic slags at two neighbouring sites in the mentioned settlement reveal that locations with many installations for the thermal processing of copper ore existed in the Bronze Age. We believe, judging by the finds of material culture, that metallurgical activities in this area also continued into the Iron Age and, possibly, into the 4th century AD. [Projekat Ministarstva nauke Republike Srbije, br. 177020: Archaeology of Serbia: Cultural identity, integration factors, technological processes and the role of the central Balkans in the development of European prehistory

  18. Vibrational characterization of different benzene phases on flat and vicinal Si(100) surfaces.

    Science.gov (United States)

    Naydenov, Borislav; Widdra, Wolf

    2007-10-21

    Based on high-resolution electron energy loss spectroscopy and temperature-programmable desorption, benzene chemisorption on vicinal and nominally flat Si(100) surfaces has been studied for various adsorption, annealing, and site blocking treatments. Three different chemisorbed benzene (C6H6 and C6D6) phases with distinct thermal desorption characteristics and different vibrational spectra have been separated and characterized on both substrates. All three phases are identified as 1,4-cyclohexadiene-like structures with butterfly geometry. Whereas the dominant phase is di-sigma bonded to the two Si atoms of a single Si-Si dimer, the benzene orientation (double bond orientation) in the other phases is rotated. Di-sigma bonding to Si atoms of adjacent Si-Si dimer for the latter cases is most likely. Coverage and temperature dependent conversions between the different phases have been addressed by vibrational spectroscopy.

  19. The fauna of small mammals in the vicinity of Temerin, The Vojvodina providence

    Directory of Open Access Journals (Sweden)

    Popović Ester J.

    2006-01-01

    Full Text Available The samples collected by traps in the vicinity of Temerin and the analysis of pellets of the long-eared owl (Asia otus and the barn owl (Tyto alba served as a basis for the determination of 409 individuals of small mammals of the orders Insectivora and Rodentia. A total of 13 species from the families Soricidae (6, Muridae (4 and Arvi-colidae (3 was recorded. The representatives of the species Apodemus sylvaticus prevailed in the sample obtained by traps while the pellet analysis showed the domination of Micro-tus arvalis in the owl diet. The presence of five of the total of thirteen species found by the pellet analysis was confirmed by means of traps.

  20. A floristic survey of Yucca Mountain and vicinity, Nye County, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Niles, W.E.; Leary, P.J.; Holland, J.S.; Landau, F.H.

    1995-12-01

    A survey of the vascular flora of Yucca Mountain and vicinity, Nye County, Nevada, was conducted from March to June 1994, and from March to October 1995. An annotated checklist of recorded taxa was compiled. Voucher plant specimens were collected and accessioned into the Herbarium at the University of Nevada, Las Vegas. Collection data accompanying these specimens were entered into that herbarium`s electronic data base. Combined results from this survey and the works of other investigators reveal the presence of a total of 375 specific and intraspecific taxa within the area these allocated to 179 genera and 54 families. No taxon currently listed as threatened or endangered under the Endangered Species Act was encountered during this study. Several candidate species for listing under this Act were present, and distributional data for these were recorded. No change in the status of these candidate species is recommended as the result of this study.

  1. Monitoring of radionuclides in the vicinities of Finnish nuclear power plants in 1993 and 1994

    Energy Technology Data Exchange (ETDEWEB)

    Klemola, S.; Ilus, E.; Ikaeheimonen, T.K

    1998-08-01

    Monitoring of radioactive substances around Finnish nuclear power plants continued in 1993-1994 in accordance with the regular programmes. Some 1000 samples are analysed annually from the terrestrial and aquatic environments of the two power plant sites. Trace amounts of activation products originating from airborne releases from the local power plants were detected in several air, deposition and soil samples. Discharged nuclides were more abundant in the aquatic environment, especially in samples of indicator organisms, sinking matter and sediments. However, the concentrations were so low that they did not significantly increase the radiation burden in the environment. The dominant artificial radionuclides in the vicinity of the power plants remained the cesium isotopes, especially {sup 137}Cs but also {sup 134}Cs, originating from the Chernobyl accident. (orig.) 14 refs.

  2. Optical characterization of gold chains and steps on the vicinal Si(557) surface: Theory and experiment

    Energy Technology Data Exchange (ETDEWEB)

    Hogan, Conor [Consiglio Nazionale delle Ricerche, Istituto di Struttura della Materia, via Fosso del Cavaliere 100, 00133 Rome (Italy); Department of Physics and European Theoretical Spectroscopy Facility (ETSF), University of Rome ' ' Tor Vergata' ' , Via della Ricerca Scientifica 1, 00133 Rome (Italy); McAlinden, Niall; McGilp, John F. [School of Physics, Trinity College Dublin, Dublin 2 (Ireland)

    2012-06-15

    We present a joint experimental-theoretical study of the reflectance anisotropy of clean and gold-covered Si(557), a vicinal surface of Si(111) upon which gold forms quasi-one-dimensional (1D) chains parallel to the steps. By means of first-principles calculations, we analyse the close relationship between the various surface structural motifs and the optical properties. Good agreement is found between experimental and computed spectra of single-step models of both clean and Au-adsorbed surfaces. Spectral fingerprints of monoatomic gold chains and silicon step edges are identified. The role of spin-orbit coupling (SOC) on the surface optical properties is examined, and found to have little effect. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. Water quality in the vicinity of Fenton Hill: Progress report, 1983 and 1984

    Energy Technology Data Exchange (ETDEWEB)

    Purtymun, W.D.; Ferenbaugh, R.W.; Becker, N.M.; Williams, M.C.; Maes, M.

    1987-01-01

    Water quality data have been collected since 1974 from established surface and groundwater stations at and in the vicinity of Fenton Hill (Hot Dry Rock Geothermal Demonstration Site) located in the Jemez Mountains. This is part of a continued program of environmental studies. There has been a slight variation in chemical quality of water from the surface and groundwater stations; however, these variations are within normal seasonal fluctuations. Water supply at the site is pumped from the aquifer in the Abiquiu Tuff. Cumulative production from 1976 through 1984 has been 41.5 x 10/sup 6/ gal. The water level in the supply well declined from 365 ft in 1976 to 379 ft in 1984.

  4. DFT study of the molybdenum-catalyzed deoxydehydration of vicinal diols.

    Science.gov (United States)

    Lupp, Daniel; Christensen, Niels Johan; Dethlefsen, Johannes R; Fristrup, Peter

    2015-02-16

    The mechanism of the molybdenum-catalyzed deoxydehydration (DODH) of vicinal diols has been investigated using density functional theory. The proposed catalytic cycle involves condensation of the diol with an Mo(VI) oxo complex, oxidative cleavage of the diol resulting in an Mo(IV) complex, and extrusion of the alkene. We have compared the proposed pathway with several alternatives, and the results have been corroborated by comparison with the molybdenum-catalyzed sulfoxide reduction recently published by Sanz et al. and with experimental observations for the DODH itself. Improved understanding of the mechanism should expedite future optimization of molybdenum-catalyzed biomass transformations. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Surface-Step-Induced Double Magnetic Switching of Fe on Vicinal W(100)

    Energy Technology Data Exchange (ETDEWEB)

    Mireles, Hector C.; Erskine, J. L.

    2001-07-16

    Two-level magnetic switching of a bilayer epitaxial Fe film grown on a graded stepped W(100) surface is observed using the magneto-optic Kerr effect. Hysteresis loops produced by the film at a location on the curved W(100) surface corresponding to a vicinal angle of 6.4{sup o} exhibit two abrupt jumps in magnetization following spin orientation perpendicular to the steps resulting from surface-step-induced anisotropy. The two-step process can be understood in terms of abrupt depinning of spins in two inequivalent microdomains associated with the stepped surface. The results suggest a new realm of ultrathin film micromagnetics in which characteristic dimensions of 20--30{angstrom} can play a dominant role.

  6. Surface-step-induced double magnetic switching of Fe on vicinal W(100).

    Science.gov (United States)

    Mireles, H C; Erskine, J L

    2001-07-16

    Two-level magnetic switching of a bilayer epitaxial Fe film grown on a graded stepped W(100) surface is observed using the magneto-optic Kerr effect. Hysteresis loops produced by the film at a location on the curved W(100) surface corresponding to a vicinal angle of 6.4 degrees exhibit two abrupt jumps in magnetization following spin orientation perpendicular to the steps resulting from surface-step-induced anisotropy. The two-step process can be understood in terms of abrupt depinning of spins in two inequivalent microdomains associated with the stepped surface. The results suggest a new realm of ultrathin film micromagnetics in which characteristic dimensions of 20-30 A can play a dominant role.

  7. Indoor Rn-222 concentrations in the vicinity of a Turkish coal-fired power plant

    Energy Technology Data Exchange (ETDEWEB)

    Yaprak, G. [Ege University, Izmir (Turkey). Inst. of Nuclear Science

    1999-10-01

    Coal, like most materials found in nature, contains natural radionuclides and their products in small quantities. Therefore, depending on their concentration in the coal, a coal-fired power plant might potentially contaminate the environment. Indoor Rn-222 concentration in 100 houses located in the vicinity of Yatagan coal-fired power plant in the southwestern part of Turkey were measured using solid state nuclear track detectors. The time-integrated Rn-222 concentrations in the houses ranged from 10 to 120 Bq m{sup -3}. This corresponds to an annual effective dose equivalent ranging from 0.6 to 7/3 mSv. In 96% of the homes, an Rn-222 concentration of 100 Bq m{sup -3} (taken as the limit for future buildings, recommended by ICRP) was not exceeded.

  8. Surface plasmon resonance on vicinity of gold-coated fiber tip

    Energy Technology Data Exchange (ETDEWEB)

    Abrahamyan, T. [Department of Radio Physics, Yerevan State University (Armenia); Nerkararyan, Kh. [Department of Radio Physics, Yerevan State University (Armenia)]. E-mail: knerkar@ysu.am

    2007-05-14

    The possibility of excitation of Surface Plasmon Polaritons (SPP) in the vicinity of the tip of a gold covered optical fiber is investigated when the tip is in the medium with a certain dielectric permittivity. In the experiment the medium was a solution consisting of dimethyl sulfoxide and ethanol liquids in which, as a result of evaporation, a smooth changing of the dielectric permittivity of the solution was taking place. During the evaporation a peak of the power of output radiation was observed from the tip of the fiber, which is explained by the resonant excitation of SPP. This mechanism of SPP excitation in the region of the tip of the optical waveguide opens up new possibilities for increasing the resolution of the nanometric scanning optical microscope and for creation of a new type of optochemical fiber sensors.

  9. Spatial distribution of marine crenarchaeota group I in the vicinity of deep-sea hydrothermal systems.

    Science.gov (United States)

    Takai, Ken; Oida, Hanako; Suzuki, Yohey; Hirayama, Hisako; Nakagawa, Satoshi; Nunoura, Takuro; Inagaki, Fumio; Nealson, Kenneth H; Horikoshi, Koki

    2004-04-01

    Distribution profiles of marine crenarchaeota group I in the vicinity of deep-sea hydrothermal systems were mapped with culture-independent molecular techniques. Planktonic samples were obtained from the waters surrounding two geographically and geologically distinct hydrothermal systems, and the abundance of marine crenarchaeota group I was examined by 16S ribosomal DNA clone analysis, quantitative PCR, and whole-cell fluorescence in situ hybridization. A much higher proportion of marine crenarchaeota group I within the microbial community was detected in deep-sea hydrothermal environments than in normal deep and surface seawaters. The highest proportion was always obtained from the ambient seawater adjacent to hydrothermal emissions and chimneys but not from the hydrothermal plumes. These profiles were markedly different from the profiles of epsilon-Proteobacteria, which are abundant in the low temperatures of deep-sea hydrothermal environments.

  10. Vinča-Belo Brdo: Vernissages of eneolithic belgrade and its vicinity I

    Directory of Open Access Journals (Sweden)

    Spasić Miloš

    2009-01-01

    Full Text Available The following paper will discuss the problems of Eneolithic settlements of Baden and Kostolac culture at Vinča near Belgrade. Eneolithic horizons from Vinča site were scarcely published owing to the fact that both Baden and Kostolac layers are not well stratified because of heavy medieval devastations. In spite of all post-depositional destructions Eneolithic settlements at Vinča show enormous significance for understanding the life of the period, both on the micro and macro-regional scale. At the same time, this work is a sort of an insight into the results of ongoing analysis of material culture and socio-economic patterns of Eneolithic period settlements in Belgrade and its vicinity.

  11. Nanostructured sapphire vicinal surfaces as templates for the growth of self-organized oxide nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Thune, E., E-mail: elsa.thune@unilim.fr [Laboratoire Sciences des Procedes Ceramiques et de Traitements de Surface (SPCTS), UMR CNRS 6638, ENSCI, 47-73 Avenue Albert Thomas, F-87065 Limoges Cedex (France); Boulle, A. [Laboratoire Sciences des Procedes Ceramiques et de Traitements de Surface (SPCTS), UMR CNRS 6638, ENSCI, 47-73 Avenue Albert Thomas, F-87065 Limoges Cedex (France); Babonneau, D.; Pailloux, F. [Laboratoire de Physique des Materiaux (PHYMAT), UMR CNRS 6630, Universite de Poitiers, Boulevard Marie et Pierre Curie - Teleport 2, BP 30179, F-86962 Futuroscope - Chasseneuil Cedex (France); Hamd, W.; Guinebretiere, R. [Laboratoire Sciences des Procedes Ceramiques et de Traitements de Surface (SPCTS), UMR CNRS 6638, ENSCI, 47-73 Avenue Albert Thomas, F-87065 Limoges Cedex (France)

    2009-11-15

    Vicinal substrates of sapphire with miscut angle of 10 deg. from the (0 0 1) planes towards the [1 1 0] direction have been annealed in air in the range from 1000 to 1500 deg. C. The behaviour of these surfaces has been characterized as a function of the temperature and the thermal treatment time by Atomic Force Microscopy observations. A thermal treatment at 1250 deg. C allows to stabilize a surface made of periodically spaced nanosized step-bunches. Such stepped surfaces were used as template to grow self-patterned epitaxial oxide nanoparticles by thermal annealing of yttria-stabilized zirconia thin films produced by sol-gel dip-coating. Grazing Incidence Small Angle X-ray Scattering and High-Resolution Transmission Electron Microscopy were used to study the morphology of the nanoparticles and their epitaxial relationships with the substrate.

  12. Wavepacket dynamics in the scattering of hydrogen anions off vicinally nano-stepped metal surfaces

    Science.gov (United States)

    Shaw, John; Chakraborty, Himadri; Monismith, David

    2017-04-01

    We study the electron dynamics in monocrystalline Cu, Au and Pd surfaces with stepped vicinal structures modeled in a Kronig-Penney scheme. The unoccupied bands of the surface is resonantly excited via the charge transfer interaction of the surface with a moving hydrogen anion. The interaction dynamics are simulated in a quantum mechanical wavepacket propagation approach that used parallel computations. The survival probability of the interacting ion is calculated as well as the electron probability density at all times during the interaction. Animated videos are produced of the electron probability density which show that, when the electron is transferred to the metal, the first two image states are the most likely locations of the electron as it evolves through the superlattice. The survival probability shows peaks at those energies that produce standing waves between the steps on the surface when the electron is in the image state subbands. The work is supported by the XSEDE allocation Grant for high performance computation.

  13. Systematic Charge-to-Mass-Dependence of Heavy Ion Spectral Breaks in Large Gradual Solar Energetic Particle Events

    Science.gov (United States)

    Desai, Mihir; Mason, Glenn; McComas, David; Cohen, Christina; Smith, Charles; Ebert, Robert; Schwadron, Nathan; Li, Gang; Mewaldt, Richard; Dayeh, Maher A.

    2016-07-01

    We fit the ˜0.1-500 MeV/nucleon H-Fe spectra in 46 large SEP events surveyed by Desai et al. (2015) with the double power-law Band function to obtain a normalization constant, low- and high-energy Band parameters γ_a and γ_b; and spectral break energy E_B. We also calculate the low-energy power-law spectral slope γ_1. Our results are: 1) γ_a, γ_1, and γ_b are species-independent and the spectra steepen with increasing energy; 2) the low-energy power-law spectral slopes γ_1 are consistent with diffusive acceleration at shocks with compression ratios between ˜2-4 as predicted by Schwadron et al. (2015); 3) the spectral breaks E_B's are well ordered by Q/M ratio, and decrease systematically with decreasing Q/M, scaling as (Q/M)^α with α in most events varying between ˜0.2-2, as predicted by Li et al (2009); 4) α is well correlated with Fe/O at ˜0.16-0.23 MeV/nucleon, but not with the ˜15-21 MeV/nucleon Fe/O and the ˜0.5-2.0 MeV/nucleon ^3He/^4He ratios; 5) In most events: α3, and O E_B increases with γ_b - γ_a; and 6) Many extreme events (associated with faster CMEs and GLEs) are Fe-rich and ^3He-rich, have α≳1.4, flatter spectra at low and high energies with γ_b - γ_a <3, and E_B that anti-correlates with γ_b - γ_a. In most events, the Q/M-dependence of E_B is consistent with the equal diffusion coefficient condition, while the event-to-event variations in α may be driven by differences in the near-shock wave intensity spectra, which are flatter than the Kolmogorov turbulence spectrum but weaker when than extreme events. We interpret these results as being due to weaker turbulence that allows the SEPs to easily escape, resulting in weaker Q/M-dependence of E_B, lower α values, and spectral steepening at higher energies. In contrast for extreme events, the stronger Q/M-dependence of E_B, larger α values, and harder spectra at high and low energy occur because enhanced wave power enables faster CME shocks to accelerate flare suprathermals

  14. Characterization of geologic deposits in the vicinity of US Ecology, Amargosa Basin, southern Nevada

    Science.gov (United States)

    Taylor, Emily M.

    2010-01-01

    Multiple approaches have been applied to better understand the characteristics of geologic units exposed at the surface and buried at depth in the vicinity of US Ecology (USE), a low-level commercial waste site in the northern Amargosa Desert, Nevada. Techniques include surficial geologic mapping and interpretation of the subsurface using borehole data. Dated deposits at depth were used to estimate rates of sediment accumulation. The subsurface lithologies have been modeled in three dimensions. Lithologic cross sections have been created from the three-dimensional model and have been compared to resistivity data at the same location. Where deposits appear offset, a fault was suspected. Global Positioning System elevation transects were measured and trenches were excavated to locate a strand of the Carrara Fault. The presence of the fault helps to better understand the shape of the potentiometric surface. These data will be used to better understand the hydrologic parameters controlling the containment of the waste at US Ecology.Quaternary geologic units exposed at the surface, in the vicinity of US Ecology, are derived from the alluvium shed off the adjacent range front and the Amargosa River. These deposits vary from modern to early Pleistocene in age. At depth, heterogeneous sands and gravel occur. Observed in deep trenches and boreholes, the subsurface deposits are characterized as fining-upward sequence of sediment from 5- to 8-meters thick. No volcanic units or fine-grained playa deposits were described in the boreholes to a depth of 200 meters. Based on Infrared Stimulated Luminescence dated core samples, short-term rates of sediment accumulation (Ecology successfully exposed offset Quaternary deposits on a splay of the Carrara Fault. Holocene deposits do not appear to be faulted, however, a fault zone does intersect middle and late Pleistocene aged units.

  15. Paleohydrologic investigations in the vicinity of Yucca Mountain: Late Quaternary paleobotanical and polynological records

    Energy Technology Data Exchange (ETDEWEB)

    Spaulding, W.G.

    1994-10-05

    The primary objective of this research in the vicinity of the proposed Yucca Mountain Nuclear Waste Repository is the detection of episodes of increased runoff and groundwater discharge in this presently arid area. Ancient, inactive spring deposits in nearby valley bottoms (Haynes, 1967; Quade, 1986; Quade and Pratt, 1989), evidence for perennial water in presently dry canyons (Spaulding, 1992), and recent claims for extraordinary increases in precipitation during the last glacial age (Forester, 1994), provide good reason to further investigate both lowland spring-discharge habitats, and upland drainages. The ultimate purpose is to assess the long-term variability of the hydrologic system in the vicinity of Yucca Mountain in response to naturally occurring climatic changes. The data generated in the course of this study are derived from radiocarbon dated packrat (Neotoma) middens. This report presents the results of an initial assessment of the hydrologic stability of the candidate area based on a limited suite of middens from localities that, on geomorphic and hydrologic grounds, could have been close to ancient stream-side or spring environments. Paleoclimatic reconstructions are another means of studying the long-term climatic hydrologic stability of the Candidate Area include, and are also generated from packrat midden data. A different flora characterized the Candidate Area during the last glacial age in response to a cooler and wetter climate, and the plant species that comprised this flora can be used to reconstruct specific components of past climatic regimes. Thus, a secondary objective of this study is to compare the plant macrofossil data generated in this study to other records from the Candidate Area (Spaulding, 1985; Wigand, 1990) to determine if these new data are consistent with prior reconstructions. 66 refs., 4 figs., 13 tabs.

  16. Step density waves on growing vicinal crystal surfaces - Theory and experiment

    Science.gov (United States)

    Ranguelov, Bogdan; Müller, Pierre; Metois, Jean-Jacques; Stoyanov, Stoyan

    2017-01-01

    The Burton, Cabrera and Frank (BCF) theory plays a key conceptual role in understanding and modeling the crystal growth of vicinal surfaces. In BCF theory the adatom concentration on a vicinal surface obeys to a diffusion equation, generally solved within quasi-static approximation where the adatom concentration at a given distance x from a step has a steady state value n (x) . Recently, we show that going beyond this approximation (Ranguelov and Stoyanov, 2007) [6], for fast surface diffusion and slow attachment/detachment kinetics of adatoms at the steps, a train of fast-moving steps is unstable against the formation of steps density waves. More precisely, the step density waves are generated if the step velocity exceeds a critical value related to the strength of the step-step repulsion. This theoretical treatment corresponds to the case when the time to reach a steady state concentration of adatoms on a given terrace is comparable to the time for a non-negligible change of the step configuration leading to a terrace adatom concentration n (x , t) that depends not only on the terrace width, but also on its "past width". This formation of step density waves originates from the high velocity of step motion and has nothing to do with usual kinetic instabilities of step bunching induced by Ehrlich-Schwoebel effect, surface electromigration and/or the impact of impurities on the step rate. The so-predicted formation of step density waves is illustrated by numerical integration of the equations for step motion. In order to complete our previous theoretical treatment of the non-stationary BCF problem, we perform an in-situ reflection electron microscopy experiment at specific temperature interval and direction of the heating current, in which, for the first time, the step density waves instability is evidenced on Si(111) surface during highest possible Si adatoms deposition rates.

  17. A MULTISTAGE GRADUAL NITROGENREDUCTION STRATEGY FOR INCREASED LIPID PRODUCTIVITY AND NITROGEN REMOVAL IN WASTEWATER USING Chlorella vulgaris AND Scenedesmus obliquus

    Directory of Open Access Journals (Sweden)

    J. C. Robles-Heredia

    2015-06-01

    Full Text Available AbstractChlorella vulgaris and Scenedesmus obliquuswere grown in artificial-wastewater using a new nitrogen-limitation strategy aimed at increasing lipid productivity. This strategy consisted in a multi-stage process with sequential reduction of N-NH4 concentration (from 90 to 60, 40, and 20 mg.L-1 to promote a balance between cell growth and lipid accumulation. Lipid productivity was compared against a reference process consisting of nitrogen reduction in two stages, where the nitrogen concentration was suddenly reduced from 90 mg.L-1 to three different concentrations (10, 20, and 30 mg.L-1. In the multi-stage mode, only C. vulgaris exhibited a net lipid-productivity increase. Lipid content of S. obliquus did not present a significant increase, thus decreasing lipid productivity. The highest lipid productivities were observed in the two-stage mode for both S. obliquus and C. vulgaris (194.9 and 133.5 mg.L-1.d-1, respectively, and these values are among the highest reported in the literature to date.

  18. Visual impairment and blindness among the students of blind schools in Allahabad and its vicinity: A causal assessment

    OpenAIRE

    Sushank Ashok Bhalerao; Mahesh Tandon; Satyaprakash Singh; Shraddha Dwivedi; Santosh Kumar; Jagriti Rana

    2015-01-01

    Background/Aims: Information on eye diseases in blind school children in Allahabad is rare and sketchy. A cross-sectional study was performed to identify causes of blindness (BL) in blind school children with an aim to gather information on ocular morbidity in the blind schools in Allahabad and in its vicinity. Study Design and Setting: A cross-sectional study was carried out in all the four blind schools in Allahabad and its vicinity. Materials and Methods: The students in the blind schools ...

  19. Influence of vicinal sapphire substrate on the properties of N-polar GaN films grown by metal-organic chemical vapor deposition

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Zhiyu; Zhang, Jincheng, E-mail: jchzhang@xidian.edu.cn; Xu, Shengrui; Chen, Zhibin; Yang, Shuangyong; Tian, Kun; Hao, Yue [Key Lab of Wide Band-Gap Semiconductor Technology, School of Microelectronics, Xidian University, Xi' an, Shaanxi 710071 (China); Su, Xujun [Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, Jiangsu 215123 (China); Shi, Xuefang [School of Advanced Materials and Nanotechnology, Xidian University, Xi' an, Shaanxi 710071 (China)

    2014-08-25

    The influence of vicinal sapphire substrates on the growth of N-polar GaN films by metal-organic chemical vapor deposition is investigated. Smooth GaN films without hexagonal surface feature are obtained on vicinal substrate. Transmission electron microscope results reveal that basal-plane stacking faults are formed in GaN on vicinal substrate, leading to a reduction in threading dislocation density. Furthermore, it has been found that there is a weaker yellow luminescence in GaN on vicinal substrate than that on (0001) substrate, which might be explained by the different trends of the carbon impurity incorporation.

  20. Driving gradual endogenous c-myc overexpression by flow-sorting: intracellular signaling and tumor cell phenotype correlate with oncogene expression

    DEFF Research Database (Denmark)

    Knudsen, Kasper Jermiin; Holm, G.M.N.; Krabbe, J.S.

    2009-01-01

    Insulin-exposed rat mammary cancer cells were flow sorted based on a c-myc reporter plasmid encoding a destabilized green fluorescent protein. Sorted cells exhibited gradual increases in c-myc levels. Cells overexpressing c-myc by only 10% exhibited phenotypic changes attributable to c-myc overex...... an alternative modeling of the receptor-mediated carcinogenic process, compared to the currently used approaches of recombinant constitutive or conditional overexpression of oncogenic transmembrane receptor tyrosine kinases or oncogenic transcription factors....

  1. A unidirecionalidade e o caráter gradual do processo de mudança por gramaticalização

    Directory of Open Access Journals (Sweden)

    Jussara Abraçado

    2006-03-01

    Full Text Available As pesquisas sobre mudança lingüística, na perspectiva funcionalista, estão, de forma geral, associadas à teoria da gramaticalização. A gramaticalização, por sua vez, costuma ser entendida como um processo de mudança gradual e unidirecional. Entretanto, alguns estudos mais recentes têm posto em questão o caráter gradual e unidirecional da gramaticalização. O propósito deste ensaio, com base em resultados de pesquisa anterior sobre aquisição pela criança de elementos dêiticos de tempo e de espaço, é o de fornecer evidências que reforçam o postulado acerca da unidirecionalidade e do caráter gradual da mudança lingüística por gramaticalização.Palavras-chave: Mudança lingüística; Gramaticalização; Unidirecionalidade.

  2. The diatom flora in the vicinity of the Pretoria Salt Pan, Transvaal, Republic of South Africa. Part III (final)

    CSIR Research Space (South Africa)

    Schoeman, FR

    1984-03-12

    Full Text Available This is the third and final contribution on the diatom flora recorded in the vicinity of the pretoria salt pan. In the taxonomic section notes and illustrations (light and electron microscopy) are given for 19 of the 35 listed species....

  3. 76 FR 60733 - Safety Zone; Mississippi River, Mile Marker 230 to Mile Marker 234, in the Vicinity of Baton...

    Science.gov (United States)

    2011-09-30

    .... Basis and Purpose The Captain of the Port New Orleans has implemented a safety zone from mile marker 230... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Mississippi River, Mile Marker 230 to Mile Marker 234, in the Vicinity of Baton Rouge, LA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule...

  4. 78 FR 35567 - Safety Zone; Lower Mississippi River, Mile Marker 219 to Mile Marker 229, in the Vicinity of Port...

    Science.gov (United States)

    2013-06-13

    ... Captain of the Port, New Orleans has implemented a safety zone from mile marker 219 to mile marker 225... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Lower Mississippi River, Mile Marker 219 to Mile Marker 229, in the Vicinity of Port Allen Lock AGENCY: Coast Guard, DHS. ACTION: Temporary final...

  5. 33 CFR 334.210 - Chesapeake Bay, in vicinity of Tangier Island; naval guided missiles test operations area.

    Science.gov (United States)

    2010-07-01

    ... Tangier Island; naval guided missiles test operations area. 334.210 Section 334.210 Navigation and... RESTRICTED AREA REGULATIONS § 334.210 Chesapeake Bay, in vicinity of Tangier Island; naval guided missiles test operations area. (a) The danger zone—(1) Prohibited area. A circle 1,000 yards in radius with its...

  6. 29 CFR 1915.95 - Ship repairing and shipbuilding work on or in the vicinity of radar and radio.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Ship repairing and shipbuilding work on or in the vicinity... STANDARDS FOR SHIPYARD EMPLOYMENT General Working Conditions § 1915.95 Ship repairing and shipbuilding work... repairing and shipbuilding. (a) No employees other than radar or radio repairmen shall be permitted to work...

  7. 14 CFR Appendix to Subpart U of... - Special Flight Rules in the Vicinity of the Grand Canyon National Park, AZ

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Special Flight Rules in the Vicinity of the Grand Canyon National Park, AZ Appendix to Subpart U of Part 93 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Special Flight Rules i...

  8. 14 CFR Special Federal Aviation... - 2-Special Flight Rules in the Vicinity of the Grand Canyon National Park, AZ

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false 2-Special Flight Rules in the Vicinity of the Grand Canyon National Park, AZ Federal Special Federal Aviation Regulation No. 50 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES GENERAL OPERATING AND FLIGHT...

  9. 129I and 137Cs in groundwater in the vicinity of Fukushima Dai-ichi nuclear power plant

    DEFF Research Database (Denmark)

    Xu, Sheng; Zhang, Luyuan; Freeman, Stewart P.H.T.

    2016-01-01

    This paper reports iodine (127I and 129I) and cesium (137Cs) isotope concentrations in groundwater of confined and unconfined aquifers in the vicinity of the Fukushima Dai-ichi nuclear power plant (FDNPP). 127I and 129I concentrations range from 2–13 μg/L and 5 × 107–8 × 1010 atom/L respectively...

  10. Monitoring of Heavy Metals Spread in the Vicinity of Combined Heat and Power Plant-3, Using Indicator Plants

    Directory of Open Access Journals (Sweden)

    Manara A. Mukasheva

    2013-01-01

    Full Text Available Examination of heavy metals content in the vicinity of Combined Heat and Power Plant-3 in Karaganda showed that all the examined plants store the detectable chemical elements in concentrations, exceeding the background ones several times. The examined plants look more suppressed, have different distortions of morphological characteristics, if compared to the background ones

  11. Surveys of forest bird populations found in the vicinity of proposed geothermal project subzones in the district of Puna, Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Jacobi, J.D.; Reynolds, M.; Ritchotte, G.; Nielsen, B.; Viggiano, A.; Dwyer, J.

    1994-10-01

    This report presents data on the distribution and status of forest bird species found within the vicinity of proposed geothermal resource development on the Island of Hawaii. Potential impacts of the proposed development on the native bird populations found in the project are are addressed.

  12. Condition and Extent of the Natural Oyster Beds and Barren Bottoms in the Vicinity of Apalachicola, Fla.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A survey of oyster beds in the vicinity of Apalachicola, FL was conducted in 1915. The area of the oyster beds is 7,135 acres, or 11.1 square miles, of which...

  13. 75 FR 43821 - Safety Zone; DEEPWATER HORIZON Response Staging Area in the Vicinity of Shell Beach, Hopedale, LA

    Science.gov (United States)

    2010-07-27

    ... SECURITY Coast Guard 33 CFR Part 165 Safety Zone; DEEPWATER HORIZON Response Staging Area in the Vicinity... Hopedale, LA in response to the DEEPWATER HORIZON oil spill. Vessels must travel at a safe speed and... This response staging area is in support of the DEEPWATER HORIZON oil spill clean-up effort. This...

  14. Deposition and properties of Fe(Se,Te) thin films on vicinal CaF2 substrates

    Science.gov (United States)

    Bryja, Hagen; Hühne, Ruben; Iida, Kazumasa; Molatta, Sebastian; Sala, Alberto; Putti, Marina; Schultz, Ludwig; Nielsch, Kornelius; Hänisch, Jens

    2017-11-01

    We report on the growth of epitaxial Fe1+δ Se0.5Te0.5 thin films on 0°, 5°, 10°, 15° and 20° vicinal cut CaF2 single crystals by pulsed laser deposition. In situ electron and ex situ x-ray diffraction studies reveal a tilted growth of the Fe1+δ Se0.5Te0.5 films, whereby under optimized deposition conditions the c-axis alignment coincides with the substrate [001] tilted axis up to a vicinal angle of 10°. Atomic force microscopy shows a flat island growth for all films. From resistivity measurements in longitudinal and transversal directions, the ab- and c-axis components of resistivity are derived and the mass anisotropy parameter is determined. Analysis of the critical current density indicates that no effective c-axis correlated defects are generated by vicinal growth, and pinning by normal point core defects dominates. However, for H∣∣ab the effective pinning centers change from surface defects to point core defects near the superconducting transition due to the vicinal cut. Furthermore, we show in angular-dependent critical current density data a shift of the ab-planes maxima position with the magnetic field strength.

  15. Lidocaine decreases the xylazine-evoked contractility in pregnant cows.

    Science.gov (United States)

    Piccinno, M; Rizzo, A; Mutinati, M; D'Onghia, G; Sciorsci, R L

    2016-08-01

    The objective of this in vitro study was to evaluate and compare the effects of xylazine on basal uterine contractility of bovine pregnant uterine strips and that of lidocaine on xylazine-sensitized bovine pregnant uterine strips, at different stages of pregnancy. Basal contractility was evaluated in an isolated organ bath and the functionality of the strips throughout the experiment was evaluated using a dose of carbachol (10(-5)M). Uterine motility, expressed with amplitude, frequency of contractions as well as the area under the curve, was recorded in different stages of pregnancy and data were collected at 15-min intervals (5-min before and 5-min after xylazine administration and 5-min after lidocaine addition on the plateau contraction induced by xylazine). Uterine motility increased in all the stages of pregnancy after xylazine addition and gradually decreased after treatment with lidocaine. These data suggest that lidocaine might decrease the tonic effect induced by xylazine on bovine pregnant uteri. Copyright © 2016. Published by Elsevier Ltd.

  16. Hydrogeochemical Investigation of the Standard Mine Vicinity, Upper Elk Creek Basin, Colorado

    Science.gov (United States)

    Manning, Andrew H.; Verplanck, Philip L.; Mast, M. Alisa; Wanty, Richard B.

    2008-01-01

    Ground- and surface-water samples were collected in the vicinity of the Standard Mine in west-central Colorado in order to characterize the local ground-water flow system, determine metal concentrations in local ground water, and better understand factors controlling the discharge of metal-rich waters from the mine. The sampling program included a one-time sampling of springs, mine adits, and exploration pits in Elk Basin and Redwell Basin; repeated sampling throughout one year of Standard Mine Level 1 discharge and Elk Creek near its confluence with Coal Creek; and a one-time sampling of underground sites in Levels 3 and 5 of the Standard Mine. Samples were analyzed for major ions and trace elements, stable isotopes of hydrogen (2H/1H) and oxygen (18O/16O), strontium isotopes, and tritium and dissolved noble gases (including helium isotopes) for tritium/helium-3 age dating. No clear correlations were observed between natural ground-water discharge locations and map-scale faults and lithology. Surface observations and the location of ground-water discharge suggest that simple topography, rather than large-scale geologic features, primarily controls the occurrence and flow of shallow ground water in Elk Basin. Discrete inflows from cross faults or other features were not observed in Levels 3 and 5 of the Standard Mine. Instead, water entered the mine as relatively persistent dripping from gouge and breccia within the Standard fault, which both tunnels follow. Therefore, the Standard fault itself is probably the main pathway of ground-water flow from the shallow subsurface to the mine workings. Low pH (as low as 3.2) and elevated concentrations of zinc, lead, cadmium, copper, and manganese (commonly exceeding water-quality standards for Elk Creek) were measured in samples located within or immediately downgradient of areas where sulfides are abundant, including the Standard fault, the Elk Lode portal, and the breccia pipe in Redwell Basin. Concentrations of these

  17. Characterizing the air quality in the vicinity of a fast-growing Asian airport

    Science.gov (United States)

    Wang, C.; Juang, J.

    2010-12-01

    Many studies have shown that air quality in the vicinity of major airports could be directly influenced by aircraft emissions, airport activities, and other forms of intense transportation in proximity to airports. There are two types of pollutants emitted within the confines of airports: one is directly emitted from aircraft engines, and the other is from ground support equipment (GSE). Such pollutants include aromatic hydrocarbon, ultrafine particles (UFP) , black carbon (BC) , nitrogen oxides, carbon monoxides, and sulfides and could immiately impact the air quality in areas downwind. Although the impact of airport emissions on surrounding communities has been studied in some major airports in North America and Europe, scant attention has been paid to airport pollution issues in Asia despite the surging growth of air travel and of airports. Commercial air traffic in Taiwan has been dramatically growing in the last two decades because of rapid economic growth and is expected to continue surging into the next decades due to increasing trade and travel with China and other countries. In this study, the air quality in the vicinity of Taiwan’s Taoyuan International Airport (TPE Airport) is analyzed to further characterize air quality in the region of a fast-growing Asian airport. Monitoring data from the Taiwanese Environmental Protection Administration (EPA) is used in the study to investigate long-term trends in air quality. The first step of this research is to analyze the data from six stations close to TPE Airport during the last ten years and to filter the attributes (wind field, geography, and so on) which could impact that air quality. Second, we characterize the relationship between data from different monitoring stations by using cluster analysis and then use the air pollution model (Industrial Source Complex-ISC3 and Cal-Puff) to identify why serious pollution events occur. Finally, we use model binds with a GIS system containing population-activity and

  18. Seismic Structure in the Vicinity of the Inner Core Boundary beneath northeastern Asia

    Science.gov (United States)

    Ibourichene, A. S.; Romanowicz, B. A.

    2016-12-01

    The inner core boundary (ICB) separates the solid inner core from the liquid outer core. The crystallization of iron occurring at this limit induces the expulsion of lighter elements such as H, O, S, Si into the outer core, generating chemically-driven convection, which provides power for the geodynamo. Both the F layer, right above the ICB, and the uppermost inner core, are affected by this process so that their properties provide important constraints for a better understanding of core dynamics and, ultimately, the generation and sustained character of the earth's magnetic field. In this study, we investigate the evolution of model parameters (P-velocity, density and quality factor) with depth in the vicinity of the ICB. For this purpose, we combine observations of two body wave phases sensitive to this region: the PKP(DF) phase refracted in the inner core and the PKiKP reflected on the ICB. Variations in the PKP(DF)/PKiKP amplitude ratio and PKP(DF)-PKiKP differential travel times can be related to structure around the ICB. We use waveform data from earthquakes located in Sumatra and recorded by the dense USArray seismic network, which allows us to sample ICB structure beneath northeastern Asia. Observed waveforms are compared to synthetics computed using the DSM method (e.g., Geller et Takeuchi, 1995) in model AK135 (e.g., Montagner & Kennett, 1996) in order to measure amplitude and travel time anomalies. Previous studies (e.g., Tanaka, 1997 ; Cao and Romanowicz, 2004, Yu and Wen, 2006; Waszek and Deuss, 2011) have observed an hemispherical pattern in the vicinity of the ICB exhibiting a faster and more attenuated eastern hemisphere compared to the western hemisphere. The region studied is located in the eastern hemisphere. We find that, on average, travel time anomalies are consistent with previous studies of the eastern hemisphere, however, amplitude ratios are not. We conduct a parameter search for the 1D model that best fits our data. We also consider

  19. Characterization of geologic deposits in the vicinity of US Ecology, Amargosa Basin, southern Nevada

    Science.gov (United States)

    Taylor, Emily M.

    2010-01-01

    Multiple approaches have been applied to better understand the characteristics of geologic units exposed at the surface and buried at depth in the vicinity of US Ecology (USE), a low-level commercial waste site in the northern Amargosa Desert, Nevada. Techniques include surficial geologic mapping and interpretation of the subsurface using borehole data. Dated deposits at depth were used to estimate rates of sediment accumulation. The subsurface lithologies have been modeled in three dimensions. Lithologic cross sections have been created from the three-dimensional model and have been compared to resistivity data at the same location. Where deposits appear offset, a fault was suspected. Global Positioning System elevation transects were measured and trenches were excavated to locate a strand of the Carrara Fault. The presence of the fault helps to better understand the shape of the potentiometric surface. These data will be used to better understand the hydrologic parameters controlling the containment of the waste at US Ecology. Quaternary geologic units exposed at the surface, in the vicinity of US Ecology, are derived from the alluvium shed off the adjacent range front and the Amargosa River. These deposits vary from modern to early Pleistocene in age. At depth, heterogeneous sands and gravel occur. Observed in deep trenches and boreholes, the subsurface deposits are characterized as fining-upward sequence of sediment from 5- to 8-meters thick. No volcanic units or fine-grained playa deposits were described in the boreholes to a depth of 200 meters. Based on Infrared Stimulated Luminescence dated core samples, short-term rates of sediment accumulation (data, when compared to lithologic cross sections, generally are consistent with lithology grain size and probable soil carbonate accumulations. Surface resistivity displays a fining-upward sequence of sediments at the surface with a soil carbonate imprint. Finally, trenching north of US Ecology successfully exposed

  20. Lead and cadmium in mushrooms from the vicinity of two large emission sources in Slovenia.

    Science.gov (United States)

    Petkovšek, Samar Al Sayegh; Pokorny, Boštjan

    2013-01-15

    Cd and Pb contents were determined in 699 samples of fruiting bodies of 55 mushrooms species, collected in the period 2000-2007 in the vicinity of the largest Slovenian thermal power plant (the Šalek Valley) and near an abandoned lead smelter (the Upper Meža Valley). The present study is the first regarding lead and cadmium in mushrooms from those exposed areas. Therefore, there was a significant lack of prior data. Among 55 studied mushroom species 36 species are edible and important from an ecotoxicological perspective. However, the remaining non-edible species are important for bioindication and allowed us to compare our results with other studies carried out in other polluted areas in Europe. The highest contents of Cd were found in Agaricus arvensis Schff.: Fr. (117 mg/kg dw) and Agaricus silvicola L.: Fr. (67.9 mg/kg dw), while the highest contents of Pb were found in Macrolepiota procera (Scop.) Singer (53.8 mg/kg dw) and Lycoperdon perlatum Pers. (50 mg/kg dw), respectively. Considering the high contents of both metals in fruiting bodies of edible fungi, together with FAO/WHO directives on tolerable levels of weekly intake of Pb/Cd by humans, it is evident that consumption of some mushroom species originating from both study areas may pose a significant human health risk. A. arvensis Schff.: Fr., A. silvicola L.: Fr. and Cortinarius caperatus (Pers.) Fr. originating from the Šalek Valley, and Armillaria mellea Vahl. P. Kumm., Boletus edulis Bull., L. perlatum Pers., Leccinum versipelle (Fr. & Hök) Snell, and M. procera (Scop.) Singer originating from the Upper Meža Valley should not be consumed at all. Our findings are consistent with some other studies, which emphasized that mushrooms from heavily polluted areas, such as in the vicinity of smelters, accumulate extremely high amounts of metals, and should therefore be omitted from human consumption. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. Attenuation of electromagnetic waves at the frequency ~1.7 kHz in the upper ionosphere observed by the DEMETER satellite in the vicinity of earthquakes

    Directory of Open Access Journals (Sweden)

    Michel Parrot

    2012-04-01

    Full Text Available

    The DEMETER satellite was the first satellite specifically dedicated to the recording of electromagnetic phenomena connected with seismic activity. Almost 6.5 years of measurements provide good opportunities to analyze a unique dataset with global Earth coverage. We present the results of a statistical study of the intensity of very low frequency electromagnetic waves recorded in the upper ionosphere. Robust two-step data processing has been used. The expected unperturbed distribution of the power spectral densities of electromagnetic emissions was calculated first. Then, the power spectral densities measured in the vicinities of earthquakes are compared with the unperturbed distribution and are examined for the presence of uncommon effects related to seismic activity. The statistical significance of the observed effects is evaluated. We confirm the previously reported results of a very small, but statistically significant, decrease in wave intensities a few hours before times of main shocks using this much larger dataset. The wave intensity decrease at a frequency of about 1.7 kHz is observed only during the night and only for shallow earthquakes. This can potentially be explained by increases in the cut-off frequency of the Earth ionosphere waveguide caused by imminent earthquakes.

     

  2. Infrared spectroscopy of one-dimensional metallic nanostructures on silicon vicinal surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Hoang, Chung Vu

    2010-06-23

    Vicinal silicon(111) surfaces are used as templates for the growth of lead nanowires as well as gold and indium atom chains. The morphology of the Au atom chains was studied by use of Scanning Tunneling Microscopy (STM) and Reflection High Energy Electron Diffraction (RHEED). The In chains were investigated by infrared spectroscopy with the electrical field component of the IR light polarized either parallel or perpendicular to the wires. It is shown that at room temperature, In atom-chains display a plasmonic absorption feature along the chain but not in the perpendicular direction. Furthermore, upon cooling down to liquid nitrogen temperature, a metal to insulator transition is observed. A structural distortion is also confirmed by RHEED. As for the result of Pb nanowires, by means of infrared spectroscopy, it is now possible to control the average length of parallel nanowire arrays by monitoring four experimental parameters that influence on the nucleation density; namely: Pb coverage, evaporation rate, substrate temperature and the surface itself. The system shows an enhancement of the absorption at the antenna frequency in the low temperature regime. This scenario is assigned to the reduction of electron-phonon scattering due to low temperature. (orig.)

  3. Past pregnancy outcomes among women living in the vicinity of a lead smelter in Kosovo, Yugoslavia

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, M.J.; Graziano, J.H.; Popovac, D.; Kline, J.K.; Mehmeti, A.; Factor-Litvak, P.; Ahmedi, G.; Shrout, P.; Rajovic, B.; Nenezic, D.U.; (Columbia Univ., New York, NY (USA))

    1990-01-01

    This analysis compares the rates of spontaneous abortion among women living in the vicinity of a lead smelter with those of women living in a town where blood lead levels were low. Data derive from the obstetric histories of both groups of women obtained while seeking prenatal care for a later pregnancy. A total of 639 women (304 exposed, 335 unexposed) had at least one previous pregnancy and lived at the same address since their first pregnancy. The geometric mean blood lead concentrations in the sample at the time of the interviews were 0.77 mumol/L in the exposed town and 0.25 mumol/L in the unexposed town. The rates of spontaneous abortions in first pregnancies were similar, with 16.4 percent of women in the exposed town and 14.0 percent in the unexposed town reporting loss. The adjusted odds ratio relating town of residence to spontaneous abortion was 1.1 (95% CI = 0.9, 1.4). This analysis represents the first systematic attempt to seek an association between environmental lead exposure and spontaneous abortion. As such, the failure to find a positive association strongly suggests that at the levels of exposure represented in our sample, such an association does not exist.

  4. The Bolgary IX settlement – a site of the Ananyino finale in the vicinity of Perm

    Directory of Open Access Journals (Sweden)

    Vasilyeva Anastasia V.

    2015-06-01

    Full Text Available The article presents materials recovered from the Bolgary IX settlement, attributed to the late Ananyino group of sites, discovered in the vicinity of the city of Perm on the left bank of the Kama River. The structures thus found were interpreted by the authors as, presumably, a dwelling (? and a cult building. The pre-Ananyino cult buildings are well known by two hillforts – Zuevy Klychi-1 on the Lower Kama and Argyzh on the Vyatka River. Small clay figurines, arrow heads, spindle whorls, small oblational cups and household ceramics were found within the cult buildings. Household ceramics are represented by some typical late Ananyino vessel forms: mainly bowls with a closed throat, sometimes with profiled pronounced neck. Some vessels have a collar on the rim. Ornamentation of the vessels includes versatile corded, combed and recessed compositions. The Bolgary IX material culture is considered in complex with simultaneous Protasy burial ground, which is located on a nearby promontory and has similar ceramics among the grave goods. This complex of sites (the settlement and the burial ground is dated back to 3rd-2nd centuries BC and is related by the authors to the period of transition from the Ananyino to the Glyadenovo cultures in the Kama River region.

  5. On the equatorial confinement of thermal plasma generated in the vicinity of the rings of Saturn

    Science.gov (United States)

    Ip, W.-H.

    1984-01-01

    Consideration of the force balance of the ring plasma generated by meteoroid impact in the rotating ionosphere of Saturn is extended to include the magnetic mirroring effect. It is found that there are modifications to the so-called siphon flow limit derived for charged particles with zero magnetic moment if the ionospheric plasma has a thermal temperature exceeding a few electron volts. The nature of the force balance is such that, instead of a sharp division between complete loss and complete reabsorption, a transition zone of partial loss appears. If part of the ions near the rings are produced by ionization of the neutral atmosphere in the vicinity of the ring system (also generated by meteoroid impact vaporization), another theoretical limit dividing the upward flow from the equatorially confined motion is located near the observed boundary between the B ring and the C ring. This new limit is very sharp, as required to explain the B-C ring boundary, which has not yet been explained by gravitational theory.

  6. Localized surface plasmon mediated energy transfer in the vicinity of core-shell nanoparticle

    Energy Technology Data Exchange (ETDEWEB)

    Shishodia, Manmohan Singh, E-mail: manmohan@gbu.ac.in; Juneja, Soniya [Department of Applied Physics, School of Vocational Studies and Applied Sciences, Gautam Buddha University, Greater Noida 201308 (India)

    2016-05-28

    Multipole spectral expansion based theory of energy transfer interactions between a donor and an acceptor molecule in the vicinity of a core-shell (nanoshell or core@shell) based plasmonic nanostructure is developed. In view of the diverse applications and rich plasmonic features such as tuning capability of surface plasmon (SP) frequencies, greater sensitivity to the change of dielectric environment, controllable redirection of electromagnetic radiation, closed form expressions for Energy Transfer Rate Enhancement Factor (ETREF) near core-shell particle are reported. The dependence of ETREF on different parameters is established through fitting equations, perceived to be of key importance for developing appropriate designs. The theoretical approach developed in the present work is capable of treating higher order multipoles, which, in turn, are also shown to play a crucial role in the present context. Moreover, closed form expressions derived in the present work can directly be used as formula, e.g., for designing SP based biosensors and estimating energy exchange between proteins and excitonic interactions in quantum dots.

  7. "Killer" Microcapsules That Can Selectively Destroy Target Microparticles in Their Vicinity.

    Science.gov (United States)

    Arya, Chandamany; Oh, Hyuntaek; Raghavan, Srinivasa R

    2016-11-02

    We have developed microscale polymer capsules that are able to chemically degrade a certain type of polymeric microbead in their immediate vicinity. The inspiration here is from the body's immune system, where killer T cells selectively destroy cancerous cells or cells infected by pathogens while leaving healthy cells alone. The "killer" capsules are made from the cationic biopolymer chitosan by a combination of ionic cross-linking (using multivalent tripolyposphate anions) and subsequent covalent cross-linking (using glutaraldehyde). During capsule formation, the enzyme glucose oxidase (GOx) is encapsulated in these capsules. The target beads are made by ionic cross-linking of the biopolymer alginate using copper (Cu(2+)) cations. The killer capsules harvest glucose from their surroundings, which is then enzymatically converted by GOx into gluconate ions. These ions are known for their ability to chelate Cu(2+) cations. Thus, when a killer capsule is next to a target alginate bead, the gluconate ions diffuse into the bead and extract the Cu(2+) cross-links, causing the disintegration of the target bead. Such destruction is visualized in real-time using optical microscopy. The destruction is specific, i.e., other microparticles that do not contain Cu(2+) are left undisturbed. Moreover, the destruction is localized, i.e., the targets destroyed in the short term are the ones right next to the killer beads. The time scale for destruction depends on the concentration of encapsulated enzyme in the capsules.

  8. Variability of cohesive sediment transport in vicinity of Sihwa tidal power plant

    Science.gov (United States)

    Ha, H. K.; Kim, J. W.; Woo, S. B.

    2016-12-01

    To investigate the disturbance of sediment dynamics in the world's largest Sihwa tidal power plant (TPP), two mooring observations have been conducted. The mooring results show that the velocity and suspended sediment concentration (SSC) were significantly disturbed over the various time scales. For the short-term (flood vs. ebb) time scale, the resuspension of bottom sediment is mainly controlled by the strong jet-flow (>2 m s-1) and resultant anticlockwise rotating vortex associated with the artificial discharge. During ebb phase, the strong flow resulted in the suspension of high-concentration near-bed sediment, transporting the suspended sediment seaward. After turning into flood phase, the vortex produced the secondary peaks of the SSC, transporting the suspended sediment toward the Sihwa TPP. The most active suspension of bed sediment predominantly occurred during 1-2 hr immediately after the start of artificial discharge. For the fortnight (spring vs. neap) time scale, the SSC during spring tide was approximately 2-5 times higher than that during neap tide. During the combined period of ebb and spring tides, in particular, the periodic artificial discharge can enhance the responses of SSC in the vicinity of Sihwa TPP.

  9. Reconnaissance hydrogeologic investigation of the Defense Waste Processing Facility and Vicinity, Savannah River Plant, South Carolina

    Energy Technology Data Exchange (ETDEWEB)

    Dennehy, K.F.; Prowell, D.C.; McMahon, P.B.

    1989-01-01

    The purposes of this report are two-fold: (1) to define the hydrogeologic conditions in the vicinity of the defense waste processing facility (DWPF) and, (2) to evaluate the potential for movement of a concentrated salt-solution waste if released at or near the DWPF. These purposes were accomplished by assembling and evaluating existing hydrogeologic data; collecting additional geologic, hydrologic, and water-quality data; developing a local geologic framework; developing a conceptual model of the local ground-water flow system; and by performing laboratory experiments to determine the mobility of salt-solution waste in surface and near-surface sediments. Although the unconsolidated sediments are about 1000 ft thick in the study area, only the Tertiary age sediments, or upper 300 ft are discussed in this report. The top of the Ellenton Formation acts as the major confining unit between the overlying aquifers in Tertiary sediments and the underlying aquifers in Cretaceous sediments; therefore, the Ellenton Formation is the vertical limit of our hydrogeologic investigation. The majority of the hydrologic data for this study come from monitoring wells at the saltstone disposal site (SDS) in Z Area (fig. 3). No recent water-level data were collected in S Area owing to the removal of S Area monitoring wells prior to construction at the DWPF. 46 refs., 26 figs., 7 tabs.

  10. New 1-arc-minute Geoids for Alaska and its Vicinity

    Science.gov (United States)

    Li, X.; Roman, D. R.; Wang, Y. M.; Saleh, J.

    2009-05-01

    A new gravimetric geoid with 1 arc minute spatial resolution has been computed for Alaska and its vicinity, ranging from 49N to 72N in latitude and 172E to 234E in longitude. More than 3 million gravity data collected by NGS (National Geodetic Survey) and other agencies such as NGA (National Geospatial-Intelligence Agency), NRCan (Natural Resources Canada), and DNSC (Danish National Space Center) are gridded into 1'x1' mean gravity anomalies, which are combined with the EGM08 coefficient model, up-to degree and order 2160, by a modified Stokes's Kernel. In addition to the improvement on the spatial resolution, the new gravimetric geoid shows about 3cm precision improvement over EGM08, compared with the geoid heights at 199 GPS leveling benchmarks in this region. Finally, a better than 2cm accurate hybrid geoid model is generated by removing both the systematic errors and the correlated signals in the differences of the gravimetric geoid at these GPS leveling benchmarks, which are modeled by a linear system and a multi-matrix covariance (Roman et. al., 2004) function,respectively.

  11. California State Waters Map Series--Hueneme Canyon and vicinity, California

    Science.gov (United States)

    Johnson, Samuel Y.; Dartnell, Peter; Cochrane, Guy R.; Golden, Nadine E.; Phillips, Eleyne L.; Ritchie, Andrew C.; Kvitek, Rikk G.; Greene, H. Gary; Krigsman, Lisa M.; Endris, Charles A.; Clahan, Kevin B.; Sliter, Ray W.; Wong, Florence L.; Yoklavich, Mary M.; Normark, William R.

    2012-01-01

    In 2007, the California Ocean Protection Council initiated the California Seafloor Mapping Program (CSMP), designed to create a comprehensive seafloor map of high-resolution bathymetry, marine benthic habitats, and geology within the 3-nautical-mile limit of California's State Waters. The CSMP approach is to create highly detailed seafloor maps through collection, integration, interpretation, and visualization of swath sonar data, acoustic backscatter, seafloor video, seafloor photography, high-resolution seismic-reflection profiles, and bottom-sediment sampling data. The map products display seafloor morphology and character, identify potential marine benthic habitats, and illustrate both the surficial seafloor geology and shallow (to about 100 m) subsurface geology. The Hueneme Canyon and vicinity map area lies within the eastern Santa Barbara Channel region of the Southern California Bight. The area is part of the Western Transverse Ranges geologic province, which is north of the California Continental Borderland. Significant clockwise rotation - at least 90° - since the early Miocene has been proposed for the Western Transverse Ranges, and the region is presently undergoing north-south shortening. This geologically complex region forms a major biogeographic transition zone, separating the cold-temperate Oregonian province north of Point Conception from the warm-temperate California province to the south. The map area, which is offshore of the Oxnard plain and west of and along the trend of the south flank of the Santa Monica Mountains, lies at the east end of the Santa Barbara littoral cell, characterized by west-to-east littoral transport of sediment derived mainly from coastal watersheds. The Hueneme Canyon and vicinity map area in California's State Waters is characterized by two major physiographic features: (1) the nearshore continental shelf, and (2) the Hueneme and Mugu Submarine Canyon system, which, in the map area, includes Hueneme Canyon and parts

  12. Scenarios constructed for nominal flow in the presence of a repository at Yucca Mountain and vicinity

    Energy Technology Data Exchange (ETDEWEB)

    Barr, G.E.; Hunter, R.L.; Dunn, E. [Sandia National Labs., Albuquerque, NM (United States); Flint, A. [Geological Survey, Mercury, NV (United States)

    1995-03-01

    Scenario development for the system performance assessment of the Yucca Mountain Site Characterization Project defines a scenario as a well-posed problem connecting an initiating event with radionuclide release to the accessible environment by a logical and physically possible combination or sequence of features, events, and processes. Drawing on the advice and assistance of the Project`s principal investigators (PIs), a collection of release scenarios initiated by the nominal ground-water flow occurring in the vicinity of the potential Yucca Mountain high-level-waste repository is developed and described in pictorial form. This collection of scenarios is intended to provide a framework to assist PIs in recognizing essential field and calculational analyses, to assist performance assessment in providing guidance to site characterization, and to continue the effort to exhaustively identify all features, events, and processes important to releases. It represents a step in the iterative process of identifying what details of the potential site are important for safe disposal. 67 refs.

  13. Wall painting of Late Antique tombs in Sirmium and its Vicinity

    Directory of Open Access Journals (Sweden)

    Popović Ivana

    2011-01-01

    Full Text Available In the east and northwest necropoles of Sirmium were discovered painted tombs which were not published until now. Painting in them is from the 4th century. The grave next to the north-west wall of basilica of St. Iraeneus (east necropolis was painted with tied garlands and stem, and partly saved frescoes from the tomb around the basilica of St. Sineros (north-west necropolis point to the conclusion that this is a funeral procession, the scene which is represented in its entirety in the tomb in neighboring Beška. These three tombs belong to the pagan population of Sirmium and its vicinity. On the west wall of the tomb in Mike Antića Street (periphery of the east necropolis is represented the motif of scales with fillings, while on its south and north wall are represented the episodes from Jonah’s cycle. Painting in the tomb shows that the buried person was a Christian. Of Christian character is also the burial in the tomb from the village Čalma, not far from Sirmium. On its longitudinal walls is schematically represented the railing, made of parts between which there were the columns carrying the herms, and which has the symbolical meaning of the “railing of Paradise”. [Projekat Ministarstva nauke Republike Srbije, br. 177007: Romanization, urbanization and transformation of urban centres of civil, military and residential character in Roman provinces on territory of Serbia

  14. The Arctic soil bacterial communities in the vicinity of a little auk colony

    Directory of Open Access Journals (Sweden)

    Sylwia Zielinska

    2016-09-01

    Full Text Available Due to deposition of birds’ guano, eggshells or feathers, the vicinity of a large seabirds’ breeding colony is expected to have a substantial impact on the soil’s physicochemical features as well as on diversity of vegetation and the soil invertebrates. Consequently, due to changing physicochemical features the structure of bacterial communities might fluctuate in different soil environments. The aim of this study was to investigate the bacterial assemblages in the Arctic soil within the area of a birds’ colony and in a control sample from a topographically similar location but situated away from the colony’s impact area. A high number of OTUs found in both areas indicates a highly complex microbial populations structure. The most abundant phyla in both of the tested samples were: Proteobacteria, Acidobacteria, Actinobacteria and Chloroflexi, with different proportions in the total share. Despite differences in the physicochemical soil characteristics, the soil microbial community structures at the phylum level were similar to some extent in the two samples. The only share that was significantly higher in the control area when compared to the sample obtained within the birds’ colony, belonged to the Actinobacteria phylum. Moreover, when analyzing the class level for each phylum, several differences between the samples were observed. Furthermore, lower proportions of Proteobacteria and Acidobacteria were observed in the soil sample under the influence of the bird’s colony, which most probably could be linked to higher nitrogen concentrations in that sample.

  15. Speciation of Cr(VI) in environmental samples in the vicinity of the ferrochrome smelter

    Energy Technology Data Exchange (ETDEWEB)

    Sedumedi, Hilda N. [Department of Chemistry, Tshwane University of Technology, P.O. Box 56208, Arcadia, 0007, Pretoria (South Africa); Mandiwana, Khakhathi L., E-mail: MandiwanaKL@tut.ac.za [Department of Chemistry, Tshwane University of Technology, P.O. Box 56208, Arcadia, 0007, Pretoria (South Africa); Ngobeni, Prince; Panichev, Nikolay [Department of Chemistry, Tshwane University of Technology, P.O. Box 56208, Arcadia, 0007, Pretoria (South Africa)

    2009-12-30

    The impact of ferrochrome smelter on the contamination of its environment with toxic hexavalent chromium, Cr(VI), was assessed by analyzing smelter dusts, soil, grass and tree barks. For the separation of Cr(VI) from Cr(III), solid samples were treated with 0.1 M Na{sub 2}CO{sub 3} and filtered through hydrophilic PDVF 0.45 {mu}m filter prior to the determination of Cr(VI) by electrothermal atomic absorption spectrometry (ET-AAS). Ferrochrome smelter dust was found to contain significant levels of Cr(VI), viz. 43.5 {mu}g g{sup -1} (cyclone dust), 2710 {mu}g g{sup -1} (fine dust), and 7800 {mu}g g{sup -1} (slimes dust) which exceeded the maximum acceptable risk concentration (20 {mu}g g{sup -1}). The concentration of Cr(VI) in environmental samples of grass (3.4 {+-} 0.2), soil (7.7 {+-} 0.2), and tree bark (11.8 {+-} 1.2) collected in the vicinity of the chrome smelter were higher as compared with the same kind of samples collected from uncontaminated area. The results of the investigation show that ferrochrome smelter is a source of environmental pollution with contamination factors of Cr(VI) ranging between 10 and 50.

  16. A floristic survey of Yucca Mountain and vicinity, Nye County, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Niles, W.E.; Leary, P.J.; Holland, J.S.; Landau, F.H.

    1994-12-01

    A survey of the vascular flora of Yucca Mountain and vicinity, Nye County, Nevada, was conducted from March to June 1994. An annotated checklist of recorded taxa was compiled. Voucher plant specimens were collected and accessioned into the Herbarium at the University of Nevada, Las Vegas. Collection data accompanying these specimens were entered into that herbarium`s electronic data base. Combined results from this survey and the works of other investigators reveal the presence of a total of 325 specific and intraspecific taxa within the area, these allocated to 162 genera and 53 families. Owing to drought conditions prevalent throughout the area, the annual floristic component was largely absent during the period of study, and it is likely much under-represented in the tabulation of results. No taxon currently listed as threatened or endangered under the Endangered Species Act was encountered during this study. Several candidate species for listing under this Act were present, and distributional data for these were recorded. No change in the status of these candidate species is recommended as the result of this survey.

  17. Radionuclide Distribution in the Soil on the Stabatishkes Site in the Vicinity of the Ignalina NPP

    Directory of Open Access Journals (Sweden)

    Jevgenij Aliončik

    2011-02-01

    Full Text Available A near surface repository for low and intermediate-level short-lived radioactive waste will be built on the Stabatiškės site in the vicinity of Ignalina NPP during decommissioning works. The reservoir can also be used for the waste stored in the temporary repositories of the Ignalina NPP. Engineering and nature protective barriers are used in the repository for radioactive waste, however, radionuclides can spread into the environment, extend in the biosphere and cause (define the external power light exposure of the environment due to the natural and premature (prescheduled degradation of the engineering barriers of the repository. The properties of the soil (acidity, quantity of organic substances, humidity are being investigated for estimating the possible migration and dispersion of radionuclides. The activity of radionuclides in the soil is also estimated before building the repository. Natural and artificial radionuclides make the pollution of the soil, and therefore the accumulation and vertical migration of artificial (137Cs, 60Co and natural (226Ra, 232Th, 40K radionuclides are being researched in the soil on the Stabatiškės site.Article in Lithuanian

  18. The use of view analyses in shaping a forest landscape in the vicinity of water reservoirs

    Directory of Open Access Journals (Sweden)

    Janeczko Emilia

    2017-09-01

    Full Text Available An increasing importance of the social functions of the forest entails the necessity to modify forestry management in a way which would ensure its social acceptance. This mainly concerns those parts of the forest that are “most visible”, in the surroundings of roads, tourist trails, as well as water bodies. The article discusses the importance of view analyses in forest landscaping. On the basis of the adopted methodological assumptions, the assessment of landscape resources of the forest in the vicinity of a water reservoir in the Kielce Forest District (Radom Regional Forest Directorate has been made. Available ortophotomaps and aerial photographs taken by UAVs were used for view analyses together with elevation data collected through airborne laser scanning. The results obtained allow to make recommendations for the protection of the reservoir exposure as well as engineering forest management and silviculture. Consequently, the inclusion of visual analyses into the planning stage enables verification of the quality of forest management plans.

  19. Lunar Infrared Spectrometer to Characterize the Hydration of Regolith in the Vicinity of a Lander

    Science.gov (United States)

    Ivanov, Andrey; Fedorova, Anna; Korablev, Oleg; Mantsevich, Sergey; Stepanov, Alexander; Kalinnikov, Yury

    Lunar Infrared Spectrometer (LIS) is an experiment onboard Luna-Globe (Luna 25) and Luna-Resurce (Luna 27) Russian surface missions. It is a pencil-beam spectrometer to be pointed by a robotic arm of the landing module, and is intended for study of the lunar surface composition in the vicinity of the lander. The instrument’s field of view (FOV) of 1(°) is co-aligned with the FOV (45(°) ) of a stereo TV camera. The spectrometer will provide measurements of selected surface areas in the spectral range of 1.15-3.3 mum. The spectral selection is provided by acousto-optic tunable filter (AOTF), which scans the spectral range sequentially. Electrical command of the AOTF allows selecting the spectral sampling, and permits a random access if needed. The spectral resolution is better than 25 cm (-1) . The instrument’s mass is 1.3 kg. The primary goal of the experiment is to detect the regolith hydration at 3mum, identifying its form from the shape of the spectrum, and to follow its changes during the day/shadow pattern. Also, LIS will allow to study the mineralogical composition from mineral signatures within the spectral range, and will serve for selection of samples to be analyzed by other instruments.

  20. Land-use planning in the vicinity of major accident hazard installations in Greece.

    Science.gov (United States)

    Sebos, Ioannis; Progiou, Athena; Symeonidis, Panagiotis; Ziomas, Ioannis

    2010-07-15

    Land-use planning, as concerns the prevention and limitation of the consequences of possible major accidents from industrial installations, is an essential mechanism for dealing with actual or potential conflicts between sources of risk, such as potentially hazardous industrial developments, and surrounding land-uses. The objective of this paper is to present a decision making methodology that is suitable for assisting urban and spatial planning in the vicinity of hazardous installations and therefore covers the directions of Article 12 of the European Council Directive 96/82/EC (the so-called SEVESO II directive). The proposed methodology was designed to address the particularities of the Greek case, regarding the type and availability of risk and spatial data. It incorporates a broad set of multiple and conflicting criteria that arise in land-use planning decisions, through the application of a well known multi-criteria decision analysis method (ELECTRE TRI). Additionally, it is easy to use (comprised of simple steps) and can be readily incorporated into Geographical Information System based platforms. 2010 Elsevier B.V. All rights reserved.

  1. POLYCYCLIC AROMATIC HYDROCARBON CONTAMINATION LEVELS IN COLLECTED SAMPLES FROM VICINITY OF A HIGHWAY

    Directory of Open Access Journals (Sweden)

    S. V. Samimi ، R. Akbari Rad ، F. Ghanizadeh

    2009-01-01

    Full Text Available Tehran as the biggest city of Iran with a population of more than 10 millions has potentially high pollutant exposures of gas oil and gasoline combustion from vehicles that are commuting in the highways every day. The vehicle exhausts contain polycyclic aromatic hydrocarbons, which are produced by incomplete combustion and can be directly deposited in the environment. In the present study, the presence of polycyclic aromatic hydrocarbons contamination in the collected samples of a western highway in Tehran was investigated. The studied location was a busy highway in Tehran. High performance liquid chromatography equipped with florescence detector was used for determination of polycyclic aromatic hydrocarbons concentrations in the studied samples. Total concentration of the ten studied polycyclic aromatic hydrocarbons compounds ranged from 11107 to 24342 ng/g dry weight in the dust samples and increased from 164 to 2886 ng/g dry weight in the soil samples taken from 300 m and middle of the highway, respectively. Also the average of Σ PAHs was 1759 ng/L in the water samples of pools in parks near the highway. The obtained results indicated that polycyclic aromatic hydrocarbons contamination levels were very high in the vicinity of the highway.

  2. Measurement of barium ion density in the vicinity of fluorescent lamp electrodes

    Science.gov (United States)

    Bhattacharya, A. K.

    1989-06-01

    A laser-induced fluorescence technique for the detection and measurement of ionized barium atoms near the vicinity of an oxide-coated electrode in a low-pressure discharge lamp is presented. Ionized Ba atoms are produced by the ionization of neutral Ba atoms in the electrode fall region of the discharge. Radiation at 455.4 nm obtained from a pulsed dye laser was used to excite Ba ii from the ground state, 62S1/2, to the resonance level, 62P3/2, and the fluorescence radiation at 614.2 nm for the 62P3/2→52D5/2 transition was measured. The number density of Ba ii atoms as determined from the measured intensity of the fluorescence signal (614.2 nm) is dependent on the discharge current, and the polarity of the neighboring electrode. It is found to be larger when it is acting as an anode than when it is a cathode.

  3. Continued Geophysical Logging in the vicinity of the GMH Electronics Superfund Site near Roxboro, North Carolina

    Science.gov (United States)

    Antolino, Dominick J.; Chapman, Melinda J.

    2016-01-01

    The collection of borehole geophysical logs and images and continuous water-level data was conducted by the U.S. Geological Survey South Atlantic Water Science Center in the vicinity of the GMH Electronics Superfund site near Roxboro, North Carolina, during December 2012 through July 2015. The study purpose was part of a continued effort to assist the U.S. Environmental Protection Agency in the development of a conceptual groundwater model for the assessment of current contaminant distribution and future migration of contaminants. Previous work by the U.S. Geological Survey South Atlantic Water Science Center at the site involved similar data collection, in addition to surface geologic mapping and passive diffusion bag sampling within monitoring wells (Chapman and others, 2013). The continued data compilation efforts included the delineation of more than 900 subsurface features (primarily fracture orientations) in 10 open borehole wells. Geophysical logs, borehole imagery, pumping data, and heat-pulse flow measurements were collected and are presented within this data release.

  4. Energetic Electron Acceleration Observed by MMS in the Vicinity of an X-Line Crossing

    Science.gov (United States)

    Jaynes, A. N.; Turner, D. L.; Wilder, F. D.; Osmane, A.; Baker, D. N.; Blake, J. B.; Fennell, J. F.; Cohen, I. J.; Mauk, B. H.; Reeves, G. D.; hide

    2016-01-01

    During the first months of observations, the Magnetospheric Multiscale Fly's Eye Energetic Particle Spectrometer instrument has observed several instances of electron acceleration up to greater than 100 keV while in the vicinity of the dayside reconnection region. While particle acceleration associated with magnetic reconnection has been seen to occur up to these energies in the tail region, it had not yet been reported at the magnetopause. This study reports on observations of electron acceleration up to hundreds of keV that were recorded on 19 September 2015 around 1000 UT, in the midst of an X-line crossing. In the region surrounding the X-line, whistler-mode and broadband electrostatic waves were observed simultaneously with the appearance of highly energetic electrons which exhibited significant energization in the perpendicular direction. The mechanisms by which particles may be accelerated via reconnection-related processes are intrinsic to understanding particle dynamics among a wide range of spatial scales and plasma environments.

  5. Tritium levels in milk in the vicinity of chronic tritium releases.

    Science.gov (United States)

    Le Goff, P; Guétat, Ph; Vichot, L; Leconte, N; Badot, P M; Gaucheron, F; Fromm, M

    2016-01-01

    Tritium is the radioactive isotope of hydrogen. It can be integrated into most biological molecules. Even though its radiotoxicity is weak, the effects of tritium can be increased following concentration in critical compartments of living organisms. For a better understanding of tritium circulation in the environment and to highlight transfer constants between compartments, we studied the tritiation of different agricultural matrices chronically exposed to tritium. Milk is one of the most frequently monitored foodstuffs in the vicinity of points known for chronic release of radionuclides firstly because dairy products find their way into most homes but also because it integrates deposition over large areas at a local scale. It is a food which contains all the main nutrients, especially proteins, carbohydrates and lipids. We thus studied the tritium levels of milk in chronic exposure conditions by comparing the tritiation of the main hydrogenated components of milk, first, component by component, then, sample by sample. Significant correlations were found between the specific activities of drinking water and free water of milk as well as between the tritium levels of cattle feed dry matter and of the main organic components of milk. Our findings stress the importance of the metabolism on the distribution of tritium in the different compartments. Overall, dilution of hydrogen in the environmental compartments was found to play an important role dimming possible isotopic effects even in a food chain chronically exposed to tritium. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Model of spatial distribution of relativistic electron fluxes in vicinity of Jupiter's moon Europa

    Science.gov (United States)

    Podzolko, Mikhail; Veselovsky, Igor; Getselev, Igor; Gubar, Yury

    This research was made as a part of a project of future space mission to the system of Jupiter, being developed by Russian Federal Space Agency. Currently several mission strategies are being considered, including placing the spacecraft into the low-altitude orbit around Jupiter’s moon Europa and possibly landing on its surface. In the region of Europa’s orbit the spacecraft will be affected by very strong radiation from the Jupiter’s radiation belts. The absorbed dose during 2 months under shielding compared to that for “Galileo” spacecraft will amount to almost 1 megarad. The major contribution to the dose will originate from relativistic electrons. However, near Europa part of the charged particle flux will be shaded by the moon. This reduction of the fluxes is nonuniform, depends on the particle energy and pitch-angle and differs for the surface and the low-altitude orbit. It is caused by a number of factors: complexity of particle trajectories relative to Europa, the flux anisotropy, variations of Europa’s position relative to Jupiter’s magnetic equator plane, magnetic and electric field disturbance in vicinity of Europa, the tenuous atmosphere of the moon. In the current study modeling of relativistic electron flux spatial distribution near Europa and on its surface and computation of the radiation doses have been made, taking into account several of mentioned above factors.

  7. Groundwater vulnerability assessment in the vicinity of Ramtha wastewater treatment plant, North Jordan

    Science.gov (United States)

    Awawdeh, Muheeb; Obeidat, Mutewekil; Zaiter, Ghusun

    2015-12-01

    The main aim of this study was to evaluate the vulnerability of groundwater to contamination in the vicinity of Ramtha wastewater treatment plant using a modified DRASTIC method in a GIS environment. A groundwater pollution potential map was prepared using modified DRASTIC method by adding lineaments and land use/land cover parameters. The values of the modified DRASTIC index were classified into three categories: low, moderate and high. About 36.5 % of the study area is occupied by the high vulnerability class, 56.5 % is occupied by the moderate vulnerability class and 9 % is occupied by the low vulnerability class. Chemical analysis of the water samples collected from wells distributed in the study area and tapping Umm Rijam aquifer indicated that the nitrate concentration ranges from 20 to 193 mg/L with an average 65.5 mg/L. Nitrate exceeded the permissible limits of WHO and Jordanian standards in 69 and 54 % of the NO3 - samples, respectively. The modified DRASTIC model was validated using nitrate concentration. Results showed a good match between nitrate concentrations level and the groundwater vulnerability classes.

  8. Dispersion of inorganic contaminants in surface water in the vicinity of Potchefstroom

    Science.gov (United States)

    Manyatshe, A.; Fosso-Kankeu, E.; van der Berg, D.; Lemmer, N.; Waanders, F.; Tutu, H.

    2017-08-01

    Potchefstroom and the neighbouring cities rely mostly on the Mooi River and Vaal River for their water needs. These rivers flow through the gold mining areas and farms, and are therefore likely to be contaminated with substantial amounts of inorganic pollutants. Water was collected along the rivers network, streams, canals and dams in Potchefstroom and the vicinity. The samples were characterized for geochemical parameters, metals and anions concentrations. The results showed high concentrations of potentially toxic elements such as As (4.53 mg/L - 5.74 mg/L), Cd (0.25 mg/L - 0.7 mg/L), Pb (1.14 mg/L - 5.13 mg/L) and U (0.04 mg/L - 0.11 mg/L) which were predominantly found around the mining areas. Elevated concentrations of anions such SO42- and CN- were detected around mining areas while NO3- was dominant near farms. The relatively high levels of anions and metals in the surface water made it unfit for domestic or agricultural use. The study showed that contaminants in mining and agricultural facilities were potentially mobilised, thus impacting the nearby water systems.

  9. Electric field measurements in the vicinity of noctilucent clouds and PMSE

    Science.gov (United States)

    Zadorozhny, Alexander M.; Tyutin, Alexander A.; Witt, Georg; Wilhelm, Nathan; Walchli, Urs; Cho, John Y. N.; Swartz, Wesley E.

    1993-01-01

    We report mesospheric electronic field structure in the vicinity of noctilucent clouds (NLC) and polar mesospheric summer echoes (PMSEs) measured on the DECIMALS-B rocket payload launched during the international rocket-radar campaign NLC-91 from Esrange, Sweden on August 10, 1991. Unusually large vertical E- fields, E(sub Z), about 100-300 mV/m on ascent and greater than 1 V/m on descent were detected at 82.5-84.5 km. The region of the large E(sub Z) was clearly limited by the NLC layer on the bottom and by the distinctly separated PMSE layer on the top. A narrow negative peak in the E(sub Z) height profile observed on ascent in the lower part of the NLC layer was apparently caused by the interaction of the field mill with impacting NLC particles possibly carrying negative charge. If the impact signature is due to single particles, their size is estimated to at least 0.5 microns and their concentration about 10(exp -4)/cu cm locally. Based on the light-scattering properties of NLC such massive particles can only be a minor part of the NLC population.

  10. Radiological health assessment of natural radioactivity in the vicinity of Obajana cement factory, North Central Nigeria

    Directory of Open Access Journals (Sweden)

    Omoniyi Matthew Isinkaye

    2015-01-01

    Full Text Available Measurements of activity concentrations of natural radionuclides in and around Obajana cement factory, North Central Nigeria have been carried out in this study to determine the activity levels of natural radionuclides in different environmental matrices in order to assess the radiological health hazards associated with the use of these matrices by the local population. A low-background Pb-shielded gamma spectroscopic counting assembly utilizing NaI (Tl detector was employed for the measurements. The results show that sediment samples have the highest activity concentrations of all the radionuclides relative to soil, farmland soil, and rock samples. The radium equivalent activity and indoor gamma dose rates together with the corresponding annual effective indoor doses evaluated were found to be lower than their permissible limits. It suffices to say, that contrary to age-long fear of radiation risks to the population in the vicinity of the cement factory, no excessive radiological health hazards either indoors and/or outdoors is envisaged. Therefore, the environmental matrices around the factory could be used without any restrictions.

  11. Selective hydrodeoxygenation of cyclic vicinal diols to cyclic alcohols over tungsten oxide-palladium catalysts.

    Science.gov (United States)

    Amada, Yasushi; Ota, Nobuhiko; Tamura, Masazumi; Nakagawa, Yoshinao; Tomishige, Keiichi

    2014-08-01

    Hydrodeoxygenation of cyclic vicinal diols such as 1,4-anhydroerythritol was conducted over catalysts containing both a noble metal and a group 5-7 transition-metal oxide. The combination of Pd and WOx allowed the removal of one of the two OH groups selectively. 3-Hydroxytetrahydrofuran was obtained from 1,4-anhydroerythritol in 72 and 74% yield over WOx -Pd/C and WOx -Pd/ZrO2 , respectively. The WOx -Pd/ZrO2 catalyst was reusable without significant loss of activity if the catalyst was calcined as a method of regeneration. Characterization of WOx -Pd/C with temperature-programmed reduction, X-ray diffraction, and transmission electron microscopy/energy-dispersive X-ray spectroscopy suggested that Pd metal particles approximately 9 nm in size were formed on amorphous tungsten oxide particles. A reaction mechanism was proposed on the basis of kinetics, reaction results with tungsten oxides under an atmosphere of Ar, and density functional theory calculations. A tetravalent tungsten center (W(IV) ) was formed by reduction of WO3 with the Pd catalyst and H2 , and this center served as the reductant for partial hydrodeoxygenation. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Survey of pickup ion signatures in the vicinity of Titan using CAPS/IMS

    Science.gov (United States)

    Regoli, L. H.; Coates, A. J.; Thomsen, M. F.; Jones, G. H.; Roussos, E.; Waite, J. H.; Krupp, N.; Cox, G.

    2016-09-01

    Pickup ion detection at Titan is challenging because ion cyclotron waves are rarely detected in the vicinity of the moon. In this work, signatures left by freshly produced pickup heavy ions (m/q ˜ 16 to m/q ˜ 28) as detected in the plasma data by the Cassini Plasma Spectrometer/Ion Mass Spectrometer (CAPS/IMS) instrument on board Cassini are analyzed. In order to discern whether these correspond to ions of exospheric origin, one of the flybys during which the reported signatures were observed is investigated in detail. For this purpose, ion composition data from time-of-flight measurements and test particle simulations to constrain the ions' origin are used. After being validated, the detection method is applied to all the flybys for which the CAPS/IMS instrument gathered valid data, constraining the region around the moon where the signatures are observed. The results reveal an escape region located in the anti-Saturn direction as expected from the nominal corotation electric field direction. These findings provide new constraints for the area of freshly produced pickup ion escape, giving an approximate escape rate of 3.3-2+3×1023 ions· s-1.

  13. What is the Uncertainty in MODIS Aerosol Optical Depth in the Vicinity of Clouds?

    Science.gov (United States)

    Patadia, Falguni; Levy, Rob; Mattoo, Shana

    2017-01-01

    MODIS dark-target (DT) algorithm retrieves aerosol optical depth (AOD) using a Look Up Table (LUT) approach. Global comparison of AOD (Collection 6 ) with ground-based sun photometer gives an Estimated Error (EE) of +/-(0.04 + 10%) over ocean. However, EE does not represent per-retrieval uncertainty. For retrievals that are biased high compared to AERONET, here we aim to closely examine the contribution of biases due to presence of clouds and per-pixel retrieval uncertainty. We have characterized AOD uncertainty at 550 nm, due to standard deviation of reflectance in 10 km retrieval region, uncertainty related to gas (H2O, O3) absorption, surface albedo, and aerosol models. The uncertainty in retrieved AOD seems to lie within the estimated over ocean error envelope of +/-(0.03+10%). Regions between broken clouds tend to have higher uncertainty. Compared to C6 AOD, a retrieval omitting observations in the vicinity of clouds (< or = 1 km) is biased by about +/- 0.05. For homogeneous aerosol distribution, clear sky retrievals show near zero bias. Close look at per-pixel reflectance histograms suggests retrieval possibility using median reflectance values.

  14. A modeling study of the time-averaged electric currents in the vicinity of isolated thunderstorms

    Science.gov (United States)

    Driscoll, Kevin T.; Blakeslee, Richard J.; Baginski, Michael E.

    1992-01-01

    A thorough examination of the results of a time-dependent computer model of a dipole thunderstorm revealed that there are numerous similarities between the time-averaged electrical properties and the steady-state properties of an active thunderstorm. Thus, the electrical behavior of the atmosphere in the vicinity of a thunderstorm can be determined with a formulation similar to what was first described by Holzer and Saxon (1952). From the Maxwell continuity equation of electric current, a simple analytical equation was derived that expresses a thunderstorm's average current contribution to the global electric circuit in terms of the generator current within the thundercloud, the intracloud lightning current, the cloud-to-ground lightning current, the altitudes of the charge centers, and the conductivity profile of the atmosphere. This equation was found to be nearly as accurate as the more computationally expensive numerical model, even when it is applied to a thunderstorm with a reduced conductivity thundercloud, a time-varying generator current, a varying flash rate, and a changing lightning mix.

  15. Turbulent flow in the vicinity of the well during the recovery state

    Science.gov (United States)

    Dimitriadis, P.

    2009-04-01

    This paper investigates turbulent flow in the vicinity of the well and focuses on the recovery state. A finite difference solution is developed for transient radially convergent Forchheimer flow to a well based on {Journal of Hydraulic Engineering, 'Approximate Solutions for Forchheimer flow to a well', Mathias S. A., Butler P. A., Zhan H., Sep. 2008}. The implications of turbulence during the recovery state are investigated. Most of the numerical models assume that turbulent head losses dissipate immediately when pumping ends. This approach does not correspond to reality. During the recovery (after the ceasing of pumping) turbulent head losses still continue to exist and there are cases where they can not be assumed negligible. This behaviour can have an important effect to the estimation of the aquifer's parameters based on the analysis of the data during the recovery area. In this paper, the time needed to pass, after the termination of pumping, for the aquifer to reach laminar flow conditions is estimated away from the well-bore to avoid borehole storage effects, based on {'Turbulent Flow to Wells', Dimitriadis P., MSc 'Hydrology for Environmental Management' dissertation, Department of Civil and Environmental Engineering, Imperial College, London, supervisor Dr. A. P. Butler, 2007}. Moreover, a methodology for the estimation of the aquifer's parameters (such as transmissivity, storativity and effective radius) based only in the recovery area is presented for discussion and two step drawdown tests are analyzed and simulated.

  16. Breakdown of metastable step-flow growth on vicinal surfaces induced by nucleation

    Science.gov (United States)

    Vilone, Daniele; Castellano, Claudio; Politi, Paolo

    2005-12-01

    We consider the growth of a vicinal crystal surface in the presence of a step-edge barrier. For any value of the barrier strength, measured by the length ℓES , nucleation of islands on terraces is always able to destroy asymptotically step-flow growth. The breakdown of the metastable step-flow occurs through the formation of a mound of critical width proportional to Lc˜1/ℓES , the length associated to the linear instability of a high-symmetry surface. The time required for the destabilization grows exponentially with Lc . Thermal detachment from steps or islands, or a steeper slope increase the instability time but do not modify the above picture, nor change Lc significantly. Standard continuum theories cannot be used to evaluate the activation energy of the critical mound and the instability time. The dynamics of a mound can be described as a one dimensional random walk for its height k ; attaining the critical height (i.e., the critical size) means that the probability to grow (k→k+1) becomes larger than the probability for the mound to shrink (k→k-1) . Thermal detachment induces correlations in the random walk, otherwise absent.

  17. A search for pulsating blue stars in the vicinity of NGC 6791 using Kepler LC data

    Directory of Open Access Journals (Sweden)

    Sowicka Paulina

    2015-01-01

    Full Text Available There are 18 known pulsating subdwarf B stars in the field of view of the Kepler spacecraft during phase one. The majority of them were observed in the short cadence mode and have been successfully investigated via asteroseismic methods. Since these stars are important for the stellar evolution theory, we performed a search for blue stars in the vicinity of the open cluster NGC 6791, which was observed by the Kepler in the long cadence mode in the so-called super apertures. We used Q1-Q17 LC data and performed pixel analysis using PyKE and our customized scripts. We preliminary tagged 23 objects and we calculated amplitude spectra to look for periodic signal which exist in the data. We found four stars with significant signal in the amplitude spectra with none of them classified as gravity modes in pulsating hot subdwarfs. Likely, all four objects are binaries, though, spectroscopic observations are needed to sort out our hypothesis.

  18. EASTERN EUROPE, A REGION OF INSECURITY IN THE EUROPEAN UNION'S VICINITY

    Directory of Open Access Journals (Sweden)

    Bogdan – Lucian Cumpanasu

    2014-08-01

    Full Text Available During Cold War, the region of Eastern Europe was formed by European states that were behind the Iron Curtain.Once the communism has fallen and former Warsaw's Pact members have joined EU in 2004 and 2007 along with the Baltic republics, a New Eastern Europe comprising Ukraine, Republic of Moldova and the Caucasian Republics emerged at the border of EU. The north, west and south maritime frontiers of European Union are opposite with Eastern territorial one that are more difficult to control and defend against asymmetrical threats as: organized crime, drugs traffic, arms proliferation and illegal immigration. this paper aims to demonstrate that EU's policies initiated in the framework of Eastern Partnership (EaP that wanted to bring peace in the Eastern neighborhood did not succeed to fulfill the desired goals. One explanation is that EU did not take in consideration the Russian dream of redesigning its sphere of influence in Eastern Europe. Another one is that the cultural, political and social differences between EU and its EaP partners led to the failure of the project. Thus, European Union's actions toward Eastern vicinity led to a clash between two civilizations: East and West as well as to a geopolitical competition between Russian Federation and EU over their shared neighborhood.

  19. Archaeological survey of the McGee Ranch vicinity, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Gard, H.A.; Poet, R.M.

    1992-09-01

    In response to a request for a cultural resources review from Westinghouse Hanford Company for the Action Plan for Characterization of McGee Ranch Soil, Pacific Northwest Laboratory`s Hanford Cultural Resources Laboratory (HCRL) conducted an archaeological survey of the McGee Ranch vicinity, located in the northwest portion of the Hanford Site. Staff members covered 8.4 km{sup 2} and recorded 42 cultural resources; 22 sites, and 20 isolated artifacts. Only 2 sites and 3 isolates were attributed to a prehistoric Native American occupation. The historic sites date from the turn of the century to the 1940s and are representative of the settlement patterns that occurred throughout the Columbia Basin. In addition to an archaeological pedestrian survey of the project area, we conducted literature and records searches and examined available aerial photographs. Records kept at HCRL were reviewed to determine if any archaeological survey had been conducted previously within the project area. Although no survey had been conducted, portions of the area adjacent to project boundaries were surveyed in 1988 and 1990. During those surveys, historic and prehistoric cultural resources were observed, increasing the possibility that similar land usage had taken place within the current project boundaries. Literature searches established a general historical sequence for this area. Aerial photographs alerted researchers to homesteads and linear features, such as roads and irrigation ditches, that might not be apparent from ground level.

  20. Archaeological survey of the McGee Ranch vicinity, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Gard, H.A.; Poet, R.M.

    1992-09-01

    In response to a request for a cultural resources review from Westinghouse Hanford Company for the Action Plan for Characterization of McGee Ranch Soil, Pacific Northwest Laboratory's Hanford Cultural Resources Laboratory (HCRL) conducted an archaeological survey of the McGee Ranch vicinity, located in the northwest portion of the Hanford Site. Staff members covered 8.4 km{sup 2} and recorded 42 cultural resources; 22 sites, and 20 isolated artifacts. Only 2 sites and 3 isolates were attributed to a prehistoric Native American occupation. The historic sites date from the turn of the century to the 1940s and are representative of the settlement patterns that occurred throughout the Columbia Basin. In addition to an archaeological pedestrian survey of the project area, we conducted literature and records searches and examined available aerial photographs. Records kept at HCRL were reviewed to determine if any archaeological survey had been conducted previously within the project area. Although no survey had been conducted, portions of the area adjacent to project boundaries were surveyed in 1988 and 1990. During those surveys, historic and prehistoric cultural resources were observed, increasing the possibility that similar land usage had taken place within the current project boundaries. Literature searches established a general historical sequence for this area. Aerial photographs alerted researchers to homesteads and linear features, such as roads and irrigation ditches, that might not be apparent from ground level.

  1. Hydrologic data and groundwater flow simulations in the vicinity of Long Lake, Indiana Dunes National Lakeshore, near Gary, Indiana

    Science.gov (United States)

    Lampe, David C.; Bayless, E. Randall

    2013-01-01

    The U.S. Geological Survey (USGS) collected data and simulated groundwater flow to increase understanding of the hydrology and the effects of drainage alterations to the water table in the vicinity of Long Lake, near Gary, Indiana. East Long Lake and West Long Lake (collectively known as Long Lake) make up one of the largest interdunal lakes within the Indiana Dunes National Lakeshore. The National Park Service is tasked with preservation and restoration of wetlands in the Indiana Dunes National Lakeshore along the southern shoreline of Lake Michigan. Urban development and engineering have modified drainage and caused changes in the distribution of open water, streams and ditches, and groundwater abundance and flow paths. A better understanding of the effects these modifications have on the hydrologic system in the area will help the National Park Service, the Gary Sanitary District (GSD), and local stakeholders manage and protect the resources within the study area.This study used hydrologic data and steady-state groundwater simulations to estimate directions of groundwater flow and the effects of various engineering controls and climatic conditions on the hydrology near Long Lake. Periods of relatively high and low groundwater levels were examined and simulated by using MODFLOW and companion software. Simulated hydrologic modifications examined the effects of (1) removing the beaver dams in US-12 ditch, (2) discontinuing seepage of water from the filtration pond east of East Long Lake, (3) discontinuing discharge from US-12 ditch to the GSD sewer system, (4) decreasing discharge from US-12 ditch to the GSD sewer system, (5) connecting East Long Lake and West Long Lake, (6) deepening County Line Road ditch, and (7) raising and lowering the water level of Lake Michigan.Results from collected hydrologic data indicate that East Long Lake functioned as an area of groundwater recharge during October 2002 and a “flow-through” lake during March 2011, with the

  2. The Gradual Expansion Muscle Flap

    Science.gov (United States)

    2014-01-01

    struck an improvised explosive device, sustaining a III-B open tibia fracture with large anteromedial soft tissue defect and bone loss involving the...GEM flap technique. The average age was 26.0 years (range, 21–39 years), and all patients were male. Four patients had sustained their injuries as a...Biochem Cytol. 1961;9:493 495. 42. Sola OM, Christensen DL, Martin AW. Hypertrophy and hyperplasia of adult chicken anterior latissimus dorsi muscles

  3. Decrease of body temperature in armadillos experimentally covered by soil.

    Science.gov (United States)

    Casanave, E B; Affanni, J M

    1995-04-01

    The armadillo Chaetophractus villosus does not stop breathing when experimentally covered with soil. Under that condition, there is a gradual but considerable drop in deep rectal temperature (TB): after 90 minutes, mean +/- SD = 1.7 +/- 0.4 degrees C (n = 8). As soon as the soil is removed and the animal breathes open air, TB gradually increases.

  4. Treatment Choice for Advanced Non-small Cell Lung Cancer Patients Who Had Gradual Progression After EGFR-TKIs: 32 Cases Report

    Directory of Open Access Journals (Sweden)

    Lin LIN

    2013-10-01

    Full Text Available Background and objective The epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs have been widely used in the treatment of the advanced non-small cell lung cancer (NSCLC, especially in the adenocarcinoma patients with activating EGFR mutations. But there is no published overview of the following treatment. This report through observing the efficacy, toxicity and overall survival of different treatments to the advanced NSCLC patients who had gradual progression after EGFR-TKIs, evaluates the influence of the continued treatment and switching chemotherapy. Methods Retrospective review is conducted on 32 cases of advanced NSCLC patients who experienced treatment failure of EGFR-TKIs. One group accepted the continued treatment and the other group accepted the switching chemotherapy. Results The median overall survival of the continued treatment group is 36.0 months. The respose rate of the switching chemotherapy group is 43.75%, and clinical benefit rate (complete and partial response and stable disease is 87.5%. The median overall survival is 15.5 months. The main toxicities are nausea, vomiting and hematological toxicities. Conclusion For the advanced NSCLC patients who had gradual progression after EGFR-TKIs, the continued treatment is one of the acceptable choices.

  5. Medea de Eurípides: la “atétesis” de versos y la construcción gradual de la venganza

    Directory of Open Access Journals (Sweden)

    Pablo A. Cavallero

    2003-12-01

    Full Text Available The work proposes to reexamine the athetesis and the emendations which were applied to diverse passages of Euripides' Medea, asserting that many of these are not necessary, if one understands the revenge as a decision whose method is not established from the beginning, but it is constructed gradually. This gradation provokes apparent contradictions. They are considered the following controverted passages: 40-43, 87, 261-2, 361-2, 366-7, 468, 725-6, 782, 785-6, 923-4, 1056-1080, 1121, 1220-1, 1316, 1359, 1387; and also all the play development, in order to prove the effect of those in the gradual construction of the revenge; it is taken into account the vocabulary use in the inside of the play. In this process, the passages here analysed, and discussed by the critics about his authenticity, result defensible and necessary to establish the graduation, which is verified in the inside structure, in the images and in the construction of the crime.

  6. Ageing as a price of cooperation and complexity: self-organization of complex systems causes the gradual deterioration of constituent networks.

    Science.gov (United States)

    Kiss, Huba J M; Mihalik, Agoston; Nánási, Tibor; Ory, Bálint; Spiró, Zoltán; Soti, Csaba; Csermely, Peter

    2009-06-01

    The network concept is increasingly used for the description of complex systems. Here, we summarize key aspects of the evolvability and robustness of the hierarchical network set of macromolecules, cells, organisms and ecosystems. Listing the costs and benefits of cooperation as a necessary behaviour to build this network hierarchy, we outline the major hypothesis of the paper: the emergence of hierarchical complexity needs cooperation leading to the ageing (i.e. gradual deterioration) of the constituent networks. A stable environment develops cooperation leading to over-optimization, and forming an 'always-old' network, which accumulates damage, and dies in an apoptosis-like process. A rapidly changing environment develops competition forming a 'forever-young' network, which may suffer an occasional over-perturbation exhausting system resources, and causing death in a necrosis-like process. Giving a number of examples we demonstrate how cooperation evokes the gradual accumulation of damage typical to ageing. Finally, we show how various forms of cooperation and consequent ageing emerge as key elements in all major steps of evolution from the formation of protocells to the establishment of the globalized, modern human society.

  7. Bender Gestalt Visual-Motor test – Sistema de Pontuação Gradual (B-SPG: A study with different samples

    Directory of Open Access Journals (Sweden)

    Ana Paula Porto Noronha

    2013-05-01

    Full Text Available The aim in this study was to analyze differences between children’s performances on the Bender – Sistema de Pontuação Gradual (B-SPG [Gradual Scoring System] in the states of Minas Gerais and Paraíba, and to compare them with the results presented in the test manual. The participants were 511 children, both sexes, aged 6-10 years ( M = 8.21, SD = 1.33, and 50.7% male. The children were from two states, Minas Gerais ( n = 298, 58.3% and Paraiba ( n = 213, 41.7%. The SPG was administered collectively in classrooms. The mean B-SPG scores between the children from Minas Gerais and Paraiba were very similar and not statistically significant. Regarding the comparison between the two states and the normative sample, three results were significant, two of which favored the children from São Paulo and the other the children from Minas Gerais and Paraíba, showing little variation in the results of the B-SPG.

  8. Driving gradual endogenous c-myc overexpression by flow-sorting: intracellular signaling and tumor cell phenotype correlate with oncogene expression.

    Science.gov (United States)

    Knudsen, Kasper Jermiin; Nelander Holm, Gitte-Mai; Krabbe, Jonas S; Listov-Saabye, Nicolai; Kiehr, Benedicte; Dufva, Martin; Svendsen, Jette E; Oleksiewicz, Martin B

    2009-12-01

    Insulin-exposed rat mammary cancer cells were flow sorted based on a c-myc reporter plasmid encoding a destabilized green fluorescent protein. Sorted cells exhibited gradual increases in c-myc levels. Cells overexpressing c-myc by only 10% exhibited phenotypic changes attributable to c-myc overexpression, such as cell cycle disturbances, increased cell size, and overexpression of the S6 ribosomal protein. Cells overexpressing c-myc by 70% exhibited additional phenotypic changes typical of c-myc overexpression, such as increased histone H3 phosphorylation, and reduced adherence. Sorted cells also exhibited overexpression of the IGF-1R, and slightly elevated expression of the IR. Increased susceptibility to the mitogenic effect of insulin was seen in a small proportion of the sorted cells, and insulin was more effective in activating the p44/42 MAPK pathway, but not the PI3K pathway, in the sorted cells than in the nonsorted cell population. To our knowledge, this is the first in vitro system allowing functional coupling between mitogenic signaling by a well-defined growth factor and gradual overexpression of the normal, endogenous c-myc gene. Thus, our flow-sorting approach provides an alternative modeling of the receptor-mediated carcinogenic process, compared to the currently used approaches of recombinant constitutive or conditional overexpression of oncogenic transmembrane receptor tyrosine kinases or oncogenic transcription factors.

  9. Airborne immissions in the vicinity of the Munich Airport; Immissionsbelastungen im Umfeld des Flughafens Muenchen

    Energy Technology Data Exchange (ETDEWEB)

    Maguhn, J.; Wimschneider, A.; Freitag, D. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Oberschleissheim (Germany). Inst. fuer Oekologische Chemie; Brotsack, R.; Spitzauer, P. [Technische Univ. Muenchen, Freising (Germany). Lehrstuhl fuer Oekologische Chemie und Umweltanalytik; Kettrup, A. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Oberschleissheim (Germany). Inst. fuer Oekologische Chemie; Technische Univ. Muenchen, Freising (Germany). Lehrstuhl fuer Oekologische Chemie und Umweltanalytik

    2000-07-01

    The airborne immissions in the eastern surroundings to the new Munich airport have been investigated by means of different analytical methods between 1992 and 1995. For a detection of environmental impacts, bioindicators were applied to determine the pollution by PAH and to quantify the pollution by photooxidants. In addition, the PAH content in the upper soil layer was determined. During high pressure weather periods in summer the actual air pollution was invetigated in the course of seven measuring compaigns. The PAH pollution of the soil is typical for rural background sites with highest concentrations in the close vicinity of busy roads, and exhibits no temporary trend. The actual input of PAH does not differ from the typical situation of rural regions in Bavaria at any measuring sites at all. Road traffic can be identified as the main PAH source in summer, whereas the considerably higher pollution in winter can be related to domestic heating. The pollution by photooxidants was found to be rather homogeneous throughout the eastern surroundings to the airport, being lowest at the sites directly influenced by road traffic. The pollution by volatile hydrocarbons at a busy road junction in the city of Erding is considerably higher than in the rural vicinity of the airport. The concentrations exhibit distinct daily courses which, among other things, can be related to atmospheric photooxidation. The hydroperoxides as secondary air pollutants exhibit an inverse course similar to that of ozone, with maximum values in the afternoon. (orig.) [German] Die Immissionsbelastung im oestlichen Umland des neuen Muenchner Flughafens wurde im Zeitraum von 1992 bis 1995 mit Hilfe einer Reihe unterschiedlicher Messmethoden untersucht. Fuer die wirkungsbezogene Erfassung von Umwelteinfluessen wurden Bioindikatoren zur Bestimmung der PAK-Belastung und zur Quantifizierung der Photooxidantienbelastung eingesetzt. Darueber hinaus wurde der PAK-Gehalt des Oberbodens bestimmt. Die

  10. Geology and ground water of the Savannah River Plant and vicinity, South Carolina

    Science.gov (United States)

    Siple, George E.

    1967-01-01

    The area described in this report covers approximately 2,600 square miles in west-central South Carolina and includes the site of the Savannah River Plant, a major production facility of the U.S. Atomic Energy Commission. The climate, surface drainage, and land forms of the study area are typical of the southern part of the Atlantic Coastal Plain. Precipitation is normally abundant and fairly evenly distributed throughout the year, and the mean annual temperature is moderately warm (64?F). The major streams that drain the area (the Savannah, Salkehatchie, and Edisto Rivers) have low gradients and flow in a southeasterly direction toward the Atlantic Ocean. Surface features of the area include narrow, flat-bottomed, steep-sided valleys and broad gently rolling interfluvial areas. Those parts of the Coastal Plain included within the report area can be subdivided into the Aiken Plateau, the Congaree Sandhills, and the Coastal Terraces. The area is underlain by a sequence of unconsolidated and partly consolidated sediments of Late Cretaceous, Tertiary, and Quaternary age. The unconsolidated sediments were deposited unconformably on a basement of igneous and metamorphic rocks of Precambrian and Paleozoic age and sedimentary rocks of Triassic age. The basement rocks are similar to the granite-diorite complex of the Charlotte Belt, the metamorphosed rocks of the Carolina Slate Belt, and the consolidated sediments of the Newark Group. The unconsolidated sediments strike about N. 60 ? E. and dip 6-20 feet per mile to the southeast. They form a wedge-shaped mass that increases in thickness toward the southeast to slightly more than 1,200 feet in the vicinity of Allendale, S.C., on the southeast or downdip side of the study area. The oldest or lowermost unconsolidated sedimentary unit, the Tuscaloosa Formation of Late Cretaceous age, is overlain in the subsurface by beds that are also probably Late Cretaceous in age and that herein are named the Ellenton Formation. The Upper

  11. Analysis of Ground Water Flow and Deformation in the Vicinity of DUSEL Homestake

    Science.gov (United States)

    Murdoch, L. C.; Ebenhack, J.; Germanovich, L. N.; Wang, H. F.; Boutt, D. F.; Onstott, T. C.; Kieft, T.; Moser, D. P.; Elsworth, D.

    2010-12-01

    The Deep Underground Science and Engineering Laboratory (DUSEL) is an underground facility planned for the workings of the former Homestake gold mine in the northern Black Hills, South Dakota. The mine workings cover several km2 in plan and extend to a depth 2.4 km. The area is underlain by Proterozoic metamorphic rocks that were deformed into regional-scale folds whose axes plunge approximately 40o to the SSE. A conceptual model and preliminary numerical analysis of the hydrogeology of the area indicates that permeability depends on effective stress, with values ranging from 0.1 mD at a depth of 2 km to 100 mD at depths of 100m. A deep ground water flow system is contained within a surface-truncated ellipsoid roughly 8 km by 4 km in plan view and 5.5 km deep with its short-axis aligned to the strike of the workings. The deep flow system consists of a zone of relatively rapid flow from the ground surface to the workings overlying the southern part of the mine, and a much larger ellipsoidal zone extending up to several km from the workings where water has been removed from storage. Numerical analyses of the ground water flow and poroelastic deformation in the vicinity of Homestake DUSEL have been refined by sharpening the 3-D resolution of important features. Mine workings have been resolved into three to four major regions where relatively large densities of rock were removed. These mined regions are shaped roughly like plunging ellipsoids with minor axes of several hundred m and major axes up to more than 2 km. They are treated in the simulations as highly permeable regions with an average elastic modulus significantly less than the intact rock; e.g. like soft, permeable inclusions. Recent field investigations and evaluation of the mine database indicate the presence of a relatively large fault that strikes approximately N20W, roughly parallel to the mined out regions. The Homestake fault dips 60NE, cutting the top of one mined region and extending beneath and

  12. Can Diuretics Decrease Your Potassium Level?

    Science.gov (United States)

    Diseases and Conditions High blood pressure (hypertension) Can diuretics decrease your potassium level? Answers from Sheldon G. Sheps, M.D. Yes, some diuretics — also called water pills — decrease potassium in the ...

  13. The sedimentological characteristics of microbialites of the Cambrian in the vicinity of Beijing, China

    Directory of Open Access Journals (Sweden)

    Yin-Ye Wu

    2017-04-01

    Full Text Available With oil and gas exploration transferring to deeper and more ancient marine strata, more researches have been conducted about the Meso–Neoproterozoic and Cambrian microbial carbonate rocks by petroleum geologists. The Cambrian deposits experienced the first transgression of the Paleozoic, with shallow marine facies depositing in most areas, which are favorable for different kinds of biological reproduction. The Lower Cambrian in Beijing area is lithologically dominated by purple red shales interbedded with limestones, the Middle Cambrian is mainly composed of thick oolitic limestones, and the Upper Cambrian consists of thin limestones and flat-pebble conglomerates. Two beds of microbial carbonate rocks were discovered in the Cambrian outcrops in the vicinity of Beijing. One is from the Zhangxia Formation of Middle Cambrian, and the other is from the Gushan Formation of Upper Cambrian. The microbialites are characterized by combination of multiple stromatolites forming different bioherms. The bioherms are mostly in oval shape and with different sizes, which are 3–4 m long, and 1–3 m high. The surrounding strata beneath the bioherms are oolitic limestones. A central core of flat-pebble conglomerates occurred within each bioherm. Wavy or columnar stromatolites grow on the basis of flat-pebble conglomerates, with dentate erosional surfaces. The bioherm carbonate rocks are interpreted as products from a deep ramp sedimentary environment where potential oil and gas reservoirs can be found. The analysis of sedimentological characteristics of bioherm carbonate rocks and its lithofacies palaeogeography has significant implication for petroleum exploration. Research on geological record of microbialites is beneficial to investigating the Earth evolution, biodiversity, palaeoenvironment and palaeoclimate change, as well as biological extinction event during geological transitions. It also gives warning to human beings of modern biological crisis.

  14. Noninteracting, vicinal frustrated P/B-Lewis pair at the norbornane framework: synthesis, characterization, and reactions.

    Science.gov (United States)

    Sajid, Muhammad; Kehr, Gerald; Wiegand, Thomas; Eckert, Hellmut; Schwickert, Christian; Pöttgen, Rainer; Cardenas, Allan Jay P; Warren, Timothy H; Fröhlich, Roland; Daniliuc, Constantin G; Erker, Gerhard

    2013-06-19

    Hydroboration of dimesitylnorbornenylphosphane with Piers' borane [HB(C6F5)2] gave the frustrated Lewis pair (FLP) 4 in good yield. It has the -PMes2 Lewis base attached at the 2-endo position and the -B(C6F5)2 group 3-exo oriented at the norbornane framework. The vicinal FLP 4 was shown by X-ray diffraction and by spectroscopy to be a rare example of an intramolecular noninteracting pair of a Lewis acid and Lewis base functionality. The FLP 4 rapidly splits dihydrogen heterolytically at ambient temperature to yield the phosphonium/hydrido borate zwitterion 5. It adds to the carbonyl group of benzaldehyde and to carbon dioxide to yield the adducts 6 and 7, respectively. Compounds 5-7 were characterized by X-ray diffraction. Compound 4 adds to the S═O function of sulfur dioxide to give a pair of diastereomeric heterocyclic six-membered ring products due to the newly formed sulfur chirality center, annulated with the norbornane skeleton, which were investigated by (31)P/(11)B single and double resonance solid state NMR experiments. Compound 8 was also characterized by X-ray diffraction. The FLP 4 undergoes a clean N,N-addition to nitric oxide (NO) to give a norbornane annulated five-membered heterocyclic persistent FLP-NO aminoxyl radical 12 (characterized, e.g., by X-ray diffraction and EPR spectroscopy). Additionally, the FLP radical was characterized by (1)H solid state NMR spectroscopy. The radical 12 undergoes a H-atom abstraction reaction with 1,4-cyclohexadiene to yield the respective diamagnetic FLP-NOH product 13, which was also characterized by X-ray diffraction and solid state NMR spectroscopy.

  15. Metabolic profiling of residents in the vicinity of a petrochemical complex

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Tzu-Hsuen; Chung, Ming-Kei [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan (China); Lin, Ching-Yu [Institute of Environmental Health, College of Public Health, National Taiwan University, Taipei, Taiwan (China); Chen, Shu-Ting; Wu, Kuen-Yuh [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan (China); Chan, Chang-Chuan, E-mail: ccchan@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan (China)

    2016-04-01

    No previous studies have simultaneously measured the biomarkers of environmental exposure and metabolome perturbation in residents affected by industrial pollutants. This study aimed to investigate the metabolic effects of environmental pollutants such as vanadium and polycyclic aromatic hydrocarbons (PAHs) on residents in the vicinity of a petrochemical complex. The study subjects were 160 residents, including 80 high-exposure subjects exposed to high levels of vanadium and PAHs and 80 age- and gender-matched low-exposure subjects living within a 40-km radius of a petrochemical complex. The exposure biomarkers vanadium and 1-hydroxypyrene and four oxidative/nitrosative stress biomarkers were measured in these subjects. Plasma samples from the study subjects were also analyzed using {sup 1}H NMR spectroscopy for metabolic profiling. The results showed that the urinary levels of vanadium and 1-hydroxypyrene in the high-exposure subjects were 40- and 20-fold higher, respectively, than those in the low-exposure subjects. Higher urinary levels of stress biomarkers, including 8-OHdG, HNE-MA, 8-isoPF2α, and 8-NO{sub 2}Gua, were also observed among the high-exposure subjects compared with the low-exposure subjects. Partial least squares discriminant analysis of the plasma metabolome demonstrated a clear separation between the high- and low-exposure subjects; the intensities of amino acids and carbohydrate metabolites were lower in the high-exposure subjects compared with the low-exposure subjects. The exposure to vanadium and PAHs may cause a reduction in the levels of amino acids and carbohydrates by elevating PPAR and insulin signaling, as well as oxidative/nitrosative stress. - Highlights: • Metabolic effects when exposure to pollutants near a petrochemical complex • V and PAHs exposure associated with elevated oxidative/nitrosative stress responses • V and PAHs exposure related to reduced amino acid and carbohydrate levels • V and PAHs affect metabolic

  16. Chemical characterization of atmospheric particles and source apportionment in the vicinity of a steelmaking industry

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, S.M., E-mail: smarta@ctn.ist.utl.pt [Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 139.7 km, 2695-066 Bobadela LRS (Portugal); Lage, J. [Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 139.7 km, 2695-066 Bobadela LRS (Portugal); Fernández, B. [Global R& D, ArcelorMittal, Avilés (Spain); Garcia, S. [Instituto de Soldadura e Qualidade, Av. Prof. Dr. Cavaco Silva, 33, 2740-120 Porto Salvo (Portugal); Reis, M.A.; Chaves, P.C. [Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 139.7 km, 2695-066 Bobadela LRS (Portugal)

    2015-07-15

    The objective of this work was to provide a chemical characterization of atmospheric particles collected in the vicinity of a steelmaking industry and to identify the sources that affect PM{sub 10} levels. A total of 94 PM samples were collected in two sampling campaigns that occurred in February and June/July of 2011. PM{sub 2.5} and PM{sub 2.5–10} were analyzed for a total of 22 elements by Instrumental Neutron Activation Analysis and Particle Induced X-ray Emission. The concentrations of water soluble ions in PM{sub 10} were measured by Ion Chromatography and Indophenol-Blue Spectrophotometry. Positive Matrix Factorization receptor model was used to identify sources of particulate matter and to determine their mass contribution to PM{sub 10}. Seven main groups of sources were identified: marine aerosol identified by Na and Cl (22%), steelmaking and sinter plant represented by As, Cr, Cu, Fe, Ni, Mn, Pb, Sb and Zn (11%), sinter plant stack identified by NH{sub 4}{sup +}, K and Pb (12%), an unidentified Br source (1.8%), secondary aerosol from coke making and blast furnace (19%), fugitive emissions from the handling of raw material, sinter plant and vehicles dust resuspension identified by Al, Ca, La, Si, Ti and V (14%) and sinter plant and blast furnace associated essentially with Fe and Mn (21%). - Highlights: • Emissions from steelworks are very complex. • The larger steelworks contribution to PM{sub 10} was from blast furnace and sinter plant. • Sinter plant stack emissions contributed for 12% of the PM{sub 10} mass. • Secondary aerosol from coke making and blast furnace contributed for 19% of the PM{sub 10}. • Fugitive dust emissions highly contribute to PM{sub 10} mass.

  17. Anthropogenic influences on groundwater in the vicinity of a long-lived radioactive waste repository

    Science.gov (United States)

    Thomas, Matthew A.; Kuhlman, Kristopher L.; Ward, Anderson L.

    2017-07-01

    The groundwater flow system in the Culebra Dolomite Member (Culebra) of the Permian Rustler Formation is a potential radionuclide release pathway from the Waste Isolation Pilot Plant (WIPP), the only deep geological repository for transuranic waste in the United States. In early conceptual models of the Culebra, groundwater levels were not expected to fluctuate markedly, except in response to long-term climatic changes, with response times on the order of hundreds to thousands of years. Recent groundwater pressures measured in monitoring wells record more than 25 m of drawdown. The fluctuations are attributed to pumping activities at a privately-owned well that may be associated with the demand of the Permian Basin hydrocarbon industry for water. The unprecedented magnitude of drawdown provides an opportunity to quantitatively assess the influence of unplanned anthropogenic forcings near the WIPP. Spatially variable realizations of Culebra saturated hydraulic conductivity and storativity were used to develop groundwater flow models to estimate a pumping rate for the private well and investigate its effect on advective transport. Simulated drawdown shows reasonable agreement with observations (average Model Efficiency coefficient = 0.7). Steepened hydraulic gradients associated with the pumping reduce estimates of conservative particle travel times across the domain by one-half and shift the intersection of the average particle track with the compliance boundary by more than two kilometers. The value of the transient simulations conducted for this study lie in their ability to (i) improve understanding of the Culebra groundwater flow system and (ii) challenge the notion of time-invariant land use in the vicinity of the WIPP.

  18. Water quality in the vicinity of Fenton Hill, 1987 and 1988. [Fenton Hill site

    Energy Technology Data Exchange (ETDEWEB)

    Purtymun, W.D.; Ferenbaugh, R.W.; Maes, M.N.; Williams, M.C.

    1991-03-01

    Water-quality data have been collected since 1974 from established surface- and ground-water stations at, and in the vicinity of, Fenton Hill (site of the Laboratory's Hot Dry Rock Geothermal Project). The site is located on the southwest edge of the Valles Caldera in the Jemez Mountains. To determine the chemical quality of water, data were collected in 1987 and 1988 from 13 surface-water stations and 19 ground-water stations. The classification of the water quality is made on the basis of predominated ions and total dissolved solids. There are four classifications of surface water (sodium and chloride, calcium and bicarbonate, calcium and sulfate, and sodium and bicarbonate) and three classifications of ground water (sodium and chloride, calcium and bicarbonate, and sodium and bicarbonate). Variations in the chemical quality of the surface and ground water in 1987 and 1988 are apparent when data are compared with each other and with previous analyses. These variations are not considered significant, as they are in the range of normal seasonal changes. Cumulative production since 1976 from the supply well at Fenton Hill has been about 63 {times} 10{sup 6} gal, with a decline in the water level of the well of about 14 ft, or about 1.4 ft/yr. The aquifer penetrated by the well is still capable of reliable supply to the site for a number of years, based on past production. The quality of water from the well has deteriorated slightly; however, the water quality is in compliance with drinking water standards. The effects of discharge from the storage ponds into an adjacent canyon have been monitored by trace metal analyses of vegetation and soil. The study indicates minimal effects, which will be undetectable in a few years if there are no further releases of effluents into the canyon. 19 refs., 6 figs., 3 tabs.

  19. Characterizing the interior of 67P in the vicinity of Abydos

    Science.gov (United States)

    Ciarletti, V.; Lasue, J.; Lemonnier, F.; Herique, A.; Kofman, W. W.; Guiffaut, C.; Levasseur-Regourd, A. C.; Plettemeier, D.

    2016-12-01

    Since the arrival of Rosetta at comet 67P, numerous pictures have been delivered by the cameras onboard both the main spacecraft and the Philae lander. They revealed, at the nucleus' surface and inside the walls of the deep pits, few-meters scale repeating structures, thus providing hints about the internal structure of the nucleus, and suggesting that primordial 'cometesimals' may be objects around 3m in size. The CONSERT (Comet Nucleus Sounding Experiment by Radiowave Transmission) experiment is a radar that has been designed to specifically sound the interior of the nucleus and to provide information on the nucleus internal structure. The work presented here is based on the CONSERT data collected during the First Science Sequence (FSS) and marginally during Philae's Separation Descent and Landing (SDL) for comparison. During FFS, the smaller lobe of the nucleus in the vicinity of Abydos has been actually sounded by CONSERT's electromagnetic waves at 90 MHz with a spatial resolution around 10 m. The propagation delays measured during FSS are consistent with a very low bulk permittivity value for the investigated cometary material, which confirms the high porosity of the nucleus. The sharp shape of the received pulses indicates that the electromagnetic waves suffered weak scattering when propagating through the nucleus. This suggests that the sounded part nucleus is thus fairly homogeneous on a spatial scale of tens of meters. We will present further results on the variation of the CONSERT's pulse shape transmitted through the small lobe of the nucleus. For a more accurate analysis and interpretation of the data, we split the FSS data into two distinct sets corresponding to soundings performed West and East of Philae in order to investigate potential differences. Tentative interpretation in terms of nucleus internal structure based on propagation simulations performed in non-homogeneous nucleus numerical models will be presented.

  20. Sea-Floor Character and Sedimentary Processes in the Vicinity of Woods Hole, Massachusetts

    Science.gov (United States)

    Poppe, Lawrence J.; McMullen, Katherine Y.; Foster, David S.; Blackwood, Dann S.; Williams, S. Jeffress; Ackerman, Seth D.; Barnum, Steven R.; Brennan, Rick T.

    2008-01-01

    Continuous-coverage multibeam bathymetric models and sidescan-sonar imagery have been verified with high-resolution seismic-reflection profiles, sediment sampling, and bottom photography. Together these data layers provide detailed base maps that yield topographic, compositional, and environmental perspectives of the sea floor in the vicinity of Woods Hole, an important harbor and major passage between the Elizabeth Islands and Cape Cod, Massachusetts. Tidally dominated high-energy environments within Woods Hole have prevented deposition of Holocene marine sediments, exposed underlying glacial drift of the Buzzards Bay moraine, and winnowed finer grained sediments, leaving lag deposits of boulders and gravel. These conditions have also enlarged and preserved depressions in the moraine surface that were originally kettle holes and formed ebb-tidal deltas at the entrances to passages. Fields of transverse and barchanoid sand waves dominate across the southern part of the study area in Vineyard Sound, where benthic environments are characterized by processes associated with coarse-bedload transport. Transverse sand waves dominate near shoals where sediment supply is greater and have asymmetries that indicate that the shoals are shaped and maintained by clockwise gyres of net sediment transport. Barchanoid sand waves, which are most common where Holocene sediments are thinner, commonly align into elongate fields that have smaller isolated waves concentrated at the eastern ends and that progressively widen and have waveforms that increase in amplitude, wavelength, and complexity westward. The northern, protected parts of the Little and Inner Harbors are characterized by muddy sediment and processes associated with deposition. A pockmark field in Little Harbor and the muddy, organic-rich sediments that form a scarp along the edge of Parker Flat are evidence for the presence of submerged marsh deposits formed during the Holocene rise in sea level.

  1. Seafloor Character and Processes in the Vicinity of Woods Hole, Massachusetts

    Science.gov (United States)

    Poppe, L. J.; McMullen, K. Y.; Williams, S.; Barnum, S. R.; Brennan, R. T.

    2009-12-01

    Continuous-coverage multibeam bathymetry and sidescan-sonar imagery have been verified with high-resolution seismic-reflection profiles, sediment sampling, and bottom photography. Together these data provide detailed base maps that yield topographic, compositional, and environmental perspectives of the seafloor in the vicinity of Woods Hole, an important harbor and major passage between the Elizabeth Islands and Cape Cod, Massachusetts. Tidally-dominated high-energy environments within Woods Hole have prevented deposition of Holocene sediments, exposed underlying glacial drift of the Buzzards Bay moraine, and winnowed finer grained sediments leaving lag deposits of boulders and gravel. Tidal currents have also enlarged and preserved depressions in the moraine surface that were originally kettle holes and formed ebb-tidal deltas at the entrances to passages. Fields of transverse and barchanoid sand waves dominate across the southern part of the study area in Vineyard Sound where benthic environments are characterized by processes associated with coarse bedload transport. Transverse sand waves dominate near shoals where sediment is available and have asymmetries indicating the shoals are shaped and maintained by clockwise gyres. Barchanoid sand waves, which are most common where Holocene sediments are thinner, commonly occur in elongate fields that have small isolated waves concentrated at their eastern ends and that progressively widen and have waveforms that increase in amplitude, wavelength, and morphological complexity westward, indicating net westward transport. The northern, lower energy parts of the Little and Great Harbors are characterized by muddy sediment and processes associated with deposition. A pockmark field in Little Harbor and the muddy organic-rich sediments that form a scarp along the eastern edge of Great Harbor are evidence for the presence of buried marsh deposits submerged during the Holocene rise in sea level.

  2. Concept for the Emergency Protection in the Vicinity of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In 1991, the Swiss Federal Nuclear Safety Inspectorate (HSK) issued a concept of the regulations for the cloud phase 1 of an nuclear power plant accident in Switzerland valid at that time in co-operation with the Federal Commission for AC Protection (KOMAC) and the Swiss Federal Nuclear Safety Commission (KSA). This concept replaced the version of 1977, which then formed the basis for emergency preparedness in Switzerland. Legal changes, such as the civil protection legislation and the ordinance on the distribution of iodine tablets to the population, as well as experience gained from the emergency exercises necessitated a revision of the existing concept. The present concept is issued by the Federal Commission for AC Protection (KOMAC) and deals with all phases of an accident sequence in a Swiss nuclear power plant focussing on the pre- and cloud phase. It also gives an overview of responsibilities and alert procedures for accidents at foreign nuclear power plants and other nuclear installations, as well as of accidents in connection with transportation of radioactive materials. The concept is designed to help the federal and cantonal authorities in the vicinity of nuclear power plants in charge of emergency protection in preparing their emergency procedure specifications, and in the realisation of the readiness for emergencies. Furthermore, it shall serve the cantons as a guideline for the preparation of emergency specifications for the communities. The concept is based on the assumption that the executive bodies and emergency forces provided for the general civil protection are employed in case of an accident at a nuclear power plant. (authors)

  3. Controlled surface functionalization via self-selective metal adsorption and pattern transformation on the vicinal Si(111) surface

    Science.gov (United States)

    Chin, A. L.; Men, F. K.; Liu, Feng

    2010-11-01

    We demonstrate a self-selective metal adsorption and pattern transformation process on vicinal Si(111) surfaces. When Au atoms are deposited onto the self-organized periodic Si(111) surface patterns, the Au atoms self-select to adsorb predominantly onto one of the two distinct domains, the Si(111) terrace or the step-bunched facet at different Au coverage. This leads to a systematic transformation of the surface pattern, whose domain population changes while its periodicity remains intact with the increasing Au coverage. A stress-domain model is used to explain the observed phenomenon. Our findings suggest a unique method for controlled functionalization of surfaces at the nanoscale, as illustrated further by domain-selective self-assembly of uniform CoSi2 nanoclusters on the Au-functionalized vicinal Si(111) surface.

  4. Controlled Surface functionalization via self-selective metal adsorption and pattern transformation on vicinal Si(111) surface

    Science.gov (United States)

    Men, F. K.; Chin, A. L.; Liu, Feng

    2011-03-01

    We demonstrate a self-selective metal adsorption and pattern transformation process on vicinal Si(111) surfaces. When Au atoms are deposited onto the self-organized periodic Si(111) surface patterns, the Au atoms self-select to adsorb predominantly onto one of the two distinct domains, the Si(111) terrace or the step-bunched facet, at different Au coverage. This leads to a systematic transformation of the surface pattern, whose domain population changes while its periodicity remains intact with the increasing Au coverage. A stress-domain model is used to explain the observed phenomenon. Our findings suggest a unique method for controlled functionalization of surfaces at the nanoscale, as illustrated further by domain- selective self-assembly of uniform CoSi 2 nanoclusters on the Au-functionalized vicinal Si(111) surface. Work supported by NSC of Taiwan, ROC (Men) and NSF and DOE-BES of US (Liu).

  5. Amelanotic melanoma in the vicinity of acquired melanocytic nevi and not arising from agminated melanocytic nevi: Masquerading as pyogenic granuloma

    Directory of Open Access Journals (Sweden)

    Angoori Gnaneshwar Rao

    2016-01-01

    Full Text Available Amelanotic melanoma (AMM presenting as pyogenic granuloma and occurring in the vicinity of acquired melanocytic nevi is rare. Herein, we report such a manifestation in a 68-year-old male who presented with the painful red nodule and multiple pigmented patches involving the left great toe. Histopathological examination of skin biopsy taken from the nodule with an immunohistochemical study using HMB45 and S-100 confirmed the diagnosis of AMM. Biopsy from the pigmented patch near the nodule showed features of melanocytic nevus. Investigative work up revealed metastatic deposits in the left inguinal lymph node with no evidence of systemic involvement, placing him in malignant melanoma Stage IIIC of American Joint Committee on Cancer (AJCC tumor node metastasis system. The development of AMM in the vicinity of acquired melanocytic nevi and manifesting as granuloma pyogenicum is unique in this case.

  6. [Assessment of cyto- and genotoxicity of natural waters in the vicinity of radioactive waste storage facility using Allium-test].

    Science.gov (United States)

    Udalova, A A; Geras'kin, S A; Dikarev, V G; Dikareva, N S

    2014-01-01

    Efficacy of bioassays of "aberrant cells frequency" and "proliferative activity" in root meristem of Allium cepa L. is studied in the present work for a cyto- and genotoxicity assessment of natural waters contaminated with 90Sr and heavy metals in the vicinity of the radioactive waste storage facility in Obninsk, Kaluga region. The Allium-test is shown to be applicable for the diagnostics of environmental media at their combined pollution with chemical and radioactive substances. The analysis of aberration spectrum shows an important role of chemical toxicants in the mutagenic potential of waters collected in the vicinity of the radioactive waste storage facility. Biological effects are not always possible to explain from the knowledge on water contamination levels, which shows limitations of physical-chemical monitoring in providing the adequate risk assessment for human and biota from multicomponent environmental impacts.

  7. Determination of magnetic anisotropies and miscut angles in epitaxial thin films on vicinal (111) substrate by the ferromagnetic resonance

    Science.gov (United States)

    Belyaev, B. A.; Izotov, A. V.; Solovev, P. N.; Yakovlev, I. A.

    2017-10-01

    A method for determining magnetic anisotropy parameters of a thin single-crystal film on vicinal (111) substrate as well as substrate miscut angles from angular dependence of ferromagnetic resonance field has been proposed. The method is based on the following: (i) a new approach for the solution of the system of nonlinear equations for equilibrium and resonance conditions; (ii) a new expression of the objective function for the fitting problem. The study of the iron silicide films grown on vicinal Si(111) substrates with different miscut angles confirmed the efficiency of the method. The proposed method can be easily generalized to determine parameters of single-crystal films grown on substrates with an arbitrary cut.

  8. A new sub-band of the acetylene-ammonia complex in the vicinity of ν4 mode of ammonia

    Science.gov (United States)

    Liu, Xunchen; Xu, Yunjie

    2012-05-01

    High resolution ro-vibrational transitions of a new sub-band of the acetylene-ammonia complex in the vicinity of ν4 mode of ammonia at 6 μm were measured. It was assigned to the perpendicular K = 0 ← 1 sub-band. Combined with the previous high resolution infrared and microwave spectroscopic study [X. Liu, Y. Xu, Phys. Chem. Chem. Phys. 13 (2011) 14235], a global fit was performed to determine the ground and upper state spectroscopic constants.

  9. A Two-Region Diffusion Model for Current-Induced Instabilities of Step Patterns on Vicinal Si(111) Surfaces

    OpenAIRE

    Zhao, T.; Weeks, J.D.

    2004-01-01

    We study current-induced step bunching and wandering instabilities with subsequent pattern formations on vicinal surfaces. A novel two-region diffusion model is developed, where we assume that there are different diffusion rates on terraces and in a small region around a step, generally arising from local differences in surface reconstruction. We determine the steady state solutions for a uniform train of straight steps, from which step bunching and in-phase wandering instabilities are deduce...

  10. A Study Of Environmental Impacts On The Coral Resources In The Vicinity Of The Saint Martin Island Bangladesh

    OpenAIRE

    Shaikh Sayed Ahammed; M. Ali Hossain; Md. Zainal Abedin; Md Abdul Khaleque

    2015-01-01

    A study of the environmental impacts on the coral resources in the vicinity of the Saint Martin Island Bangladesh was conducted with a view to making an assessment of the current status of coral resources in the island and identifying major natural and anthropogenic environmental threats to the future sustainability of these resources. It is evident that the coral resources have been reduced significantly and currently only 41 coral species are available. The existing environmental condition...

  11. Characteristics of highly stacked InAs quantum-dot laser grown on vicinal (001)InP substrate

    Science.gov (United States)

    Akahane, Kouichi; Umezawa, Toshimasa; Matsumoto, Atsushi; Yamamoto, Naokatsu; Kawanishi, Tetsuya

    2016-04-01

    We fabricate broad-area laser diodes consisting of 30-layer stacks of InAs quantum dots by using a strain-compensation technique on a vicinal (001)InP substrate. These laser diodes exhibit ground-state lasing at 1576 nm in the pulsed mode with a high characteristic temperature of 111 K at around room temperature (20-80 °C).

  12. A multiwavelength study of star formation in the vicinity of Galactic HII region Sh2-100

    OpenAIRE

    Samal, M. R.; Pandey, A. K.; Ojha, D. K.; Ghosh, S.K.; Kulkarni, V. K.; Kusakabe, N.; Tamura, M; Bhatt, B. C.; Thompson, M.A.; Sagar, R

    2010-01-01

    We present multiwavelength investigation of morphology, physical-environment, stellar contents and star formation activity in the vicinity of star-forming region Sh 2-100. It is found that the Sh 2-100 region contains seven HII regions of ultracompact and compact nature. The present estimation of distance for three HII regions, along with the kinematic distance for others, suggests that all of them belong to the same molecular cloud complex. Using NIR photometry, we identified the most probab...

  13. The Impact of Tourism on the Socio-Cultural Environment in the Gorce National Park and its Vicinity

    OpenAIRE

    Luberda, Małgorzata

    2014-01-01

    The paper presents the problems of tourism in terms of its relationship with the social as well as cultural environment. The purpose of the article was to examine how tourism affects the socio-cultural environment in the Gorce National Park and its vicinity. I examined whether tourist traffic in the Park brings about more benefits or problems, and whether changes taking place in communities visited by tourists are positive or negative? The impact of tourism on the socio-cult...

  14. Study of e(+)e(-) -> p(p)over-bar pi(0) in the vicinity of the psi

    NARCIS (Netherlands)

    Ablikim, M.; Achasov, M. N.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; An, F. F.; An, Q.; Bai, J. Z.; Ferroli, R. Baldini; Ban, Y.; Bennett, J. V.; Bertani, M.; Bian, J. M.; Boger, E.; Bondarenko, O.; Boyko, I.; Braun, S.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Chu, Y. P.; Cronin-Hennessy, D.; Dai, H. L.; Dai, J. P.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; Ding, W. M.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Du, S. X.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, Y.; Fava, L.; Feng, C. Q.; Fu, C. D.; Fuks, O.; Gao, Q.; Gao, Y.; Geng, C.; Goetzen, K.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, T.; Guo, Y. P.; Han, Y. L.; Harris, F. A.; He, K. L.; He, M.; He, Z. Y.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Huang, G. M.; Huang, G. S.; Huang, H. P.; Huang, J. S.; Huang, L.; Huang, X. T.; Huang, Y.; Hussain, T.; Ji, C. S.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. L.; Jiang, L. W.; Jiang, X. S.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Kloss, B.; Kopf, B.; Kornicer, M.; Kuehn, W.; Kupsc, A.; Lai, W.; Lange, J. S.; Lara, M.; Larin, P.; Leyhe, M.; Li, C. H.; Li, Cheng; Li, Cui; Li, D.; Li, D. M.; Li, F.; Li, G.; Li, H. B.; Li, J. C.; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, Q. J.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Lin, D. X.; Liu, B. J.; Liu, C. L.; Liu, C. X.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. P.; Liu, K.; Liu, K. Y.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqiang; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, G. R.; Lu, H. J.; Lu, H. L.; Lu, J. G.; Lu, X. R.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lv, M.; Ma, F. C.; Ma, H. L.; Ma, Q. M.; Ma, S.; Ma, T.; Ma, X. Y.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Messchendorp, J. G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Moeini, H.; Morales, C. Morales; Moriya, K.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Ping, J. L.; Ping, R. G.; Poling, R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, X. S.; Qin, Y.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Ruan, X. D.; Sarantsev, A.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, X. Y.; Sheng, H. Y.; Shepherd, M. R.; Song, W. M.; Song, X. Y.; Spataro, S.; Spruck, B.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Toth, D.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, Q. J.; Wang, S. G.; Wang, W.; Wang, X. F.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Wei, D. H.; Wei, J. B.; Weidenkaff, P.; Wen, S. P.; Werner, M.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, N.; Wu, Z.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Xue, Z.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. X.; Yang, L.; Yang, Y.; Yang, Y. X.; Ye, H.; Ye, M.; Ye, M. H.; Yu, B. X.; Yu, C. X.; Yu, H. W.; Yu, J. S.; Yu, S. P.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zang, S. L.; Zeng, Y.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. B.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, S. H.; Zhang, X. J.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, X. H.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, Li; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zou, B. S.; Zou, J. H.

    2014-01-01

    The process e(+)e(-) -> p (p) over bar pi(0) has been studied by analyzing data collected at root s = 3.773 GeV, root s = 3.650 GeV, and during a psi(3770) line shape scan with the BESIII detector at the BEPCII collider. The Born cross section of p (p) over bar pi(0) in the vicinity of the psi(3770)

  15. Adding tsetse control to medical activities contributes to decreasing transmission of sleeping sickness in the Mandoul focus (Chad).

    Science.gov (United States)

    Mahamat, Mahamat Hissene; Peka, Mallaye; Rayaisse, Jean-Baptiste; Rock, Kat S; Toko, Mahamat Abdelrahim; Darnas, Justin; Brahim, Guihini Mollo; Alkatib, Ali Bachar; Yoni, Wilfrid; Tirados, Inaki; Courtin, Fabrice; Brand, Samuel P C; Nersy, Cyrus; Alfaroukh, Idriss Oumar; Torr, Steve J; Lehane, Mike J; Solano, Philippe

    2017-07-01

    Gambian sleeping sickness or HAT (human African trypanosomiasis) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by riverine species of tsetse. A global programme aims to eliminate the disease as a public health problem by 2020 and stop transmission by 2030. In the South of Chad, the Mandoul area is a persistent focus of Gambian sleeping sickness where around 100 HAT cases were still diagnosed and treated annually until 2013. Pre-2014, control of HAT relied solely on case detection and treatment, which lead to a gradual decrease in the number of cases of HAT due to annual screening of the population. Because of the persistence of transmission and detection of new cases, we assessed whether the addition of vector control to case detection and treatment could further reduce transmission and consequently, reduce annual incidence of HAT in Mandoul. In particular, we investigated the impact of deploying 'tiny targets' which attract and kill tsetse. Before tsetse control commenced, a census of the human population was conducted and their settlements mapped. A pre-intervention survey of tsetse distribution and abundance was implemented in November 2013 and 2600 targets were deployed in the riverine habitats of tsetse in early 2014, 2015 and 2016. Impact on tsetse and on the incidence of sleeping sickness was assessed through nine tsetse monitoring surveys and four medical surveys of the human population in 2014 and 2015. Mathematical modelling was used to assess the relative impact of tsetse control on incidence compared to active and passive screening. The census indicated that a population of 38674 inhabitants lived in the vicinity of the Mandoul focus. Within this focus in November 2013, the vector is Glossina fuscipes fuscipes and the mean catch of tsetse from traps was 0.7 flies/trap/day (range, 0-26). The catch of tsetse from 44 sentinel biconical traps declined after target deployment with only five tsetse being caught in nine

  16. Adding tsetse control to medical activities contributes to decreasing transmission of sleeping sickness in the Mandoul focus (Chad.

    Directory of Open Access Journals (Sweden)

    Mahamat Hissene Mahamat

    2017-07-01

    Full Text Available Gambian sleeping sickness or HAT (human African trypanosomiasis is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by riverine species of tsetse. A global programme aims to eliminate the disease as a public health problem by 2020 and stop transmission by 2030. In the South of Chad, the Mandoul area is a persistent focus of Gambian sleeping sickness where around 100 HAT cases were still diagnosed and treated annually until 2013. Pre-2014, control of HAT relied solely on case detection and treatment, which lead to a gradual decrease in the number of cases of HAT due to annual screening of the population.Because of the persistence of transmission and detection of new cases, we assessed whether the addition of vector control to case detection and treatment could further reduce transmission and consequently, reduce annual incidence of HAT in Mandoul. In particular, we investigated the impact of deploying 'tiny targets' which attract and kill tsetse. Before tsetse control commenced, a census of the human population was conducted and their settlements mapped. A pre-intervention survey of tsetse distribution and abundance was implemented in November 2013 and 2600 targets were deployed in the riverine habitats of tsetse in early 2014, 2015 and 2016. Impact on tsetse and on the incidence of sleeping sickness was assessed through nine tsetse monitoring surveys and four medical surveys of the human population in 2014 and 2015. Mathematical modelling was used to assess the relative impact of tsetse control on incidence compared to active and passive screening.The census indicated that a population of 38674 inhabitants lived in the vicinity of the Mandoul focus. Within this focus in November 2013, the vector is Glossina fuscipes fuscipes and the mean catch of tsetse from traps was 0.7 flies/trap/day (range, 0-26. The catch of tsetse from 44 sentinel biconical traps declined after target deployment with only five tsetse being

  17. Fine-Scale Ecological and Genetic Population Structure of Two Whitefish (Coregoninae) Species in the Vicinity of Industrial Thermal Emissions.

    Science.gov (United States)

    Graham, Carly F; Eberts, Rebecca L; Morgan, Thomas D; Boreham, Douglas R; Lance, Stacey L; Manzon, Richard G; Martino, Jessica A; Rogers, Sean M; Wilson, Joanna Y; Somers, Christopher M

    2016-01-01

    Thermal pollution from industrial processes can have negative impacts on the spawning and development of cold-water fish. Point sources of thermal effluent may need to be managed to avoid affecting discrete populations. Correspondingly, we examined fine-scale ecological and genetic population structure of two whitefish species (Coregonus clupeaformis and Prosopium cylindraceum) on Lake Huron, Canada, in the immediate vicinity of thermal effluent from nuclear power generation. Niche metrics using δ13C and δ15N stable isotopes showed high levels of overlap (48.6 to 94.5%) in resource use by adult fish captured in areas affected by thermal effluent compared to nearby reference locations. Isotopic niche size, a metric of resource use diversity, was 1.3- to 2.8-fold higher than reference values in some thermally affected areas, indicative of fish mixing. Microsatellite analyses of genetic population structure (Fst, STRUCTURE and DAPC) indicated that fish captured at all locations in the vicinity of the power plant were part of a larger population extending beyond the study area. In concert, ecological and genetic markers do not support the presence of an evolutionarily significant unit in the vicinity of the power plant. Thus, future research should focus on the potential impacts of thermal emissions on development and recruitment.

  18. [Social and economic consequences of night-time aircraft noise in the vicinity of Frankfurt/Main airport].

    Science.gov (United States)

    Greiser, E; Glaeske, G

    2013-03-01

    A prospective calculation of disease-related social and economic costs due to night-time aircraft noise in the vicinity of Frankfurt/Main airport was performed for the calendar years 2012-2021. It was based on risk estimates for a variety of diagnostic entities (cardiovascular disease, depression, psychosis, diabetes mellitus, dementia and Alzheimer's disease, all cancers except malignancies of the respiratory system) from a previous case-control study on more than 1 million persons enrolled in compulsory sickness funds in the vicinity of the Cologne-Bonn airport, on disease-related cost estimates performed by the German Federal Statistical Office for the calender years 2002-2008, and calculations of the population exposed to night-time aircraft noise in the vicinity of Frankfurt/Main airport (2005 aircraft routes and flight frequencies). Total estimated costs came to more than 1.5 billion € with an excess of 23 400 cases of diseases treated in hospitals and of 3 400 subsequent deaths. © Georg Thieme Verlag KG Stuttgart · New York.

  19. Decreased serum homocysteine levels after micronutrient supplementation in older people

    Directory of Open Access Journals (Sweden)

    Pusparini Pusparini

    2016-02-01

    Full Text Available Aging is associated with a gradual impairment in cognitive function. The elderly also show a high prevalence of undernutrition, whereas nutrition plays an important role in the metabolism of neuronal cells and enzymes. Homocysteine is an amino acid resulting from methionine metabolism and is dependent on intake of vitamin B12, vitamin B6 and folic acid. Homocysteine is said to play a role in cognitive function. The objective of this study was to evaluate the effect of micronutrient supplementation for 6 months on serum homocysteine levels and cognitive function in older people. This study was an experimental study of pre-post test design, carried out in Mampang subdistrict, South Jakarta. A total of 94 elderly people was recruited for this study, consisting of 44 females and 50 males. Serum homocysteine level was assessed by fluorescent polarization immunoassay and cognitive function by means of the mini mental state examination (MMSE before and after micronutrient supplementation. Mean serum homocysteine concentration after supplementation decreased significantly to 14.8 ± 5.8 mmol/L, compared with mean serum homocysteine level of 15.9 ± 5.9 mmol/L before supplementation (p=0.000. Multiple regression analysis indicated that the factors influencing post-supplementation MMSE scores were gender (â=-0.350; p=0.000, education (â=0.510; p=0.000 and post-supplementation homocysteine levels (â=-0.201; p=0.000, while age, pre-supplementation homocysteine levels and BMI did not affect MMSE scores. Homocysteine concentration decreased significantly after 6 months of supplementation. The factors affecting post-supplementation MMSE scores were gender, level of education, and post-supplementation homocysteine level.

  20. Decreased serum homocysteine levels after micronutrient supplementation in older people

    Directory of Open Access Journals (Sweden)

    Pusparini

    2010-12-01

    Full Text Available Aging is associated with a gradual impairment in cognitive function. The elderly also show a high prevalence of undernutrition, whereas nutrition plays an important role in the metabolism of neuronal cells and enzymes. Homocysteine is an amino acid resulting from methionine metabolism and is dependent on intake of vitamin B12, vitamin B6 and folic acid. Homocysteine is said to play a role in cognitive function. The objective of this study was to evaluate the effect of micronutrient supplementation for 6 months on serum homocysteine levels and cognitive function in older people. This study was an experimental study of pre-post test design, carried out in Mampang subdistrict, South Jakarta. A total of 94 elderly people was recruited for this study, consisting of 44 females and 50 males. Serum homocysteine level was assessed by fluorescent polarization immunoassay and cognitive function by means of the mini mental state examination (MMSE before and after micronutrient supplementation. Mean serum homocysteine concentration after supplementation decreased significantly to 14.8 ± 5.8 mmol/L, compared with mean serum homocysteine level of 15.9 ± 5.9 mmol/L before supplementation (p=0.000. Multiple regression analysis indicated that the factors influencing post-supplementation MMSE scores were gender (â=-0.350; p=0.000, education (â=0.510; p=0.000 and post-supplementation homocysteine levels (â=-0.201; p=0.000, while age, pre-supplementation homocysteine levels and BMI did not affect MMSE scores. Homocysteine concentration decreased significantly after 6 months of supplementation. The factors affecting post-supplementation MMSE scores were gender, level of education, and post-supplementation homocysteine level.

  1. Transmission electron microscopy and photoluminescence characterization of InGaAs strained quantum wires on GaAs vicinal (110) substrates

    CERN Document Server

    Shim, B R; Ota, T; Kobayashi, K; Maehashi, K; Nakashima, H; Lee, S Y

    1999-01-01

    We have used transmission electron microscopy (TEM) and photoluminescence (PL) to study InGaAs/AlGaAs strained quantum wires (QWRs) grown by molecular beam epitaxy (MBE) on GaAs vicinal (110) substrates. The cross-sectional TEM image reveals that InGaAs QWRs structures are naturally formed on AlGaAs giant steps. In the plan-view TEM images, the fringe pattern in the giant-step region is observed for In sub x Ga sub 1 sub - sub x As layers with x<= 0.4 We measured the separation of the fringe in the plan-view TEM images and compared the result with the calculated fringe separation. From this result, we conclude that the fringes observed in the plan-view TEM images are moire fringes. PL spectra of the InGaAs QWRs samples reveal 80-meV shifts to lower energy with respect to the spectrum of a quantum well (QWL) grown on a (001) substrate under the same conditions. We also measured the polarization anisotropy of the PL spectra from the QWRs. The PL peak shifts systematically toward higher energy with decreasing...

  2. Assessment of urinary thiodiglycolic acid exposure in school-aged children in the vicinity of a petrochemical complex in central Taiwan.

    Science.gov (United States)

    Huang, Po-Chin; Liu, Li-Hsuan; Shie, Ruei-Hao; Tsai, Chih-Hsin; Liang, Wei-Yen; Wang, Chih-Wen; Tsai, Cheng-Hsien; Chiang, Hung-Che; Chan, Chang-Chuan

    2016-10-01

    School-aged children living in the vicinity of vinyl chloride (VCM)/polyvinyl chloride (PVC) factories may have an increased risk of exposure to hazardous air pollutants. We aimed to evaluate the urinary thiodiglycolic acid (TDGA) level, as TDGA is a major metabolite of VCM, for students at elementary schools near a petrochemical complex in central Taiwan. We recruited 343 students from 5 elementary schools based on distance to the VCM/PVC factory. First-morning urine and blood samples were obtained from our subjects from October 2013 to September 2014. Urine samples were analyzed for urinary creatinine and TDGA using LC/MS-MS. Hepatitis virus infection were assessed using blood samples. We determined their vitamin consumption, resident location, parent's employment, and other demographic or lifestyle characteristics using a questionnaire. Median urinary TDGA levels for 316 students at 5 elementary schools from the closest (schools. Further, median urinary TDGA levels for students during school time were 4.1-fold higher than those during summer vacation. After adjusting for confounders, urinary TDGA levels for the school-aged children decreased with increasing distances between the elementary schools and the petrochemical complex. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Heavy metal contamination of soil and water in the vicinity of an abandoned e-waste recycling site: implications for dissemination of heavy metals.

    Science.gov (United States)

    Wu, Qihang; Leung, Jonathan Y S; Geng, Xinhua; Chen, Shejun; Huang, Xuexia; Li, Haiyan; Huang, Zhuying; Zhu, Libin; Chen, Jiahao; Lu, Yayin

    2015-02-15

    Illegal e-waste recycling activity has caused heavy metal pollution in many developing countries, including China. In recent years, the Chinese government has strengthened enforcement to impede such activity; however, the heavy metals remaining in the abandoned e-waste recycling site can still pose ecological risk. The present study aimed to investigate the concentrations of heavy metals in soil and water in the vicinity of an abandoned e-waste recycling site in Longtang, South China. Results showed that the surface soil of the former burning and acid-leaching sites was still heavily contaminated with Cd (>0.39 mg kg(-1)) and Cu (>1981 mg kg(-1)), which exceeded their respective guideline levels. The concentration of heavy metals generally decreased with depth in both burning site and paddy field, which is related to the elevated pH and reduced TOM along the depth gradient. The pond water was seriously acidified and contaminated with heavy metals, while the well water was slightly contaminated since heavy metals were mostly retained in the surface soil. The use of pond water for irrigation resulted in considerable heavy metal contamination in the paddy soil. Compared with previous studies, the reduced heavy metal concentrations in the surface soil imply that heavy metals were transported to the other areas, such as pond. Therefore, immediate remediation of the contaminated soil and water is necessary to prevent dissemination of heavy metals and potential ecological disaster. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Magnetization plateau as a result of the uniform and gradual electron doping in a coupled spin-electron double-tetrahedral chain

    Science.gov (United States)

    Gálisová, Lucia

    2017-11-01

    The double-tetrahedral chain in a longitudinal magnetic field, whose nodal lattice sites occupied by the localized Ising spins regularly alternate with triangular plaquettes with the dynamics described by the Hubbard model, is rigorously investigated. It is demonstrated that the uniform change of electron concentration controlled by the chemical potential in a combination with the competition between model parameters and the external magnetic field leads to the formation of one chiral and seven nonchiral phases at the absolute zero temperature. Rational plateaux at one-third and one-half of the saturation magnetization can also be identified in the low-temperature magnetization curves. On the other hand, the gradual electron doping results in 11 different ground-state regions that distinguish from each other by the evolution of the electron distribution during this process. Several doping-dependent magnetization plateaux are observed in the magnetization process as a result of the continuous change of electron content in the model.

  5. Determining the area of influence of depression cone in the vicinity of lignite mine by means of triangle method and LANDSAT TM/ETM+ satellite images.

    Science.gov (United States)

    Zawadzki, Jarosław; Przeździecki, Karol; Miatkowski, Zygmunt

    2016-01-15

    Problems with lowering of water table are common all over the world. Intensive pumping of water from aquifers for consumption, irrigation, industrial or mining purposes often causes groundwater depletion and results in the formation of cone of depression. This can severely decrease water pressure, even over vast areas, and can create severe problems such as degradation of agriculture or natural environment sometimes depriving people and animals of water supply. In this paper, the authors present a method for determining the area of influence of a groundwater depression cone resulting from prolonged drainage, by means of satellite images in optical, near infrared and thermal infrared bands from TM sensor (Thematic Mapper) and ETM+ sensor (Enhanced Thematic Mapper +) placed on Landsat 5 and Landsat 7 satellites. The research area was Szczercowska Valley (Pol. Kotlina Szczercowska), Central Poland, located within a range of influence of a groundwater drainage system of the lignite coal mine in Belchatow. It is the biggest lignite coal mine in Poland and one of the largest in Europe exerting an enormous impact on the environment. The main method of satellite data analysis for determining soil moisture, was the so-called triangle method. This method, based on TVDI (Temperature Vegetation Dryness Index) was supported by additional spatial analysis including ordinary kriging used in order to combine fragmentary information obtained from areas covered by meadows. The results obtained are encouraging and confirm the usefulness of the triangle method not only for soil moisture determination but also for assessment of the temporal and spatial changes in the area influenced by the groundwater depression cone. The range of impact of the groundwater depression cone determined by means of above-described remote sensing analysis shows good agreement with that determined by ground measurements. The developed satellite method is much faster and cheaper than in-situ measurements

  6. Gradual disordering of the native state on a slow two-state folding protein monitored by single-molecule fluorescence spectroscopy and NMR.

    Science.gov (United States)

    Campos, Luis A; Sadqi, Mourad; Liu, Jianwei; Wang, Xiang; English, Douglas S; Muñoz, Victor

    2013-10-24

    Theory predicts that folding free energy landscapes are intrinsically malleable and as such are expected to respond to perturbations in topographically complex ways. Structural changes upon perturbation have been observed experimentally for unfolded ensembles, folding transition states, and fast downhill folding proteins. However, the native state of proteins that fold in a two-state fashion is conventionally assumed to be structurally invariant during unfolding. Here we investigate how the native and unfolded states of the chicken α-spectrin SH3 domain (a well characterized slow two-state folder) change in response to chemical denaturants and/or temperature. We can resolve the individual properties of the two end-states across the chemical unfolding transition employing single-molecule fluorescence spectroscopy (SM-FRET) and across the thermal unfolding transition by NMR because SH3 folds-unfolds in the slow chemical exchange regime. Our results demonstrate that α-spectrin SH3 unfolds in a canonical way in the sense that it converts between the native state and an unfolded ensemble that expands in response to chemical denaturants. However, as conditions become increasingly destabilizing, the native state also expands gradually, and a large fraction of its native intramolecular hydrogen bonds break up. This gradual disordering of the native state takes place in times shorter than the 100 μs resolution of our SM-FRET experiments. α-Spectrin SH3 thus showcases the extreme plasticity of folding landscapes, which extends to the native state of slow two-state proteins. Our results point to the idea that folding mechanisms under physiological conditions might be quite different from those obtained by linear extrapolation from denaturing conditions. Furthermore, they highlight a pressing need for re-evaluating the conventional procedures for analyzing and interpreting folding experiments, which may be based on too-simplistic assumptions.

  7. Le profil SVP : sismique au voisinage du puits The Wvp (Well Vicinity Profiling Stack

    Directory of Open Access Journals (Sweden)

    Blondin E.

    2006-11-01

    Full Text Available L'augmentation de l'investigation latérale du PSV (profil sismique vertical et le calage de la sismique de surface au puits peuvent être améliorés en combinant un profil sismique réflexion de surface d'une mise en oeuvre particulière (à base réceptrice fixe appelé SVP (sismique au voisinage du puits et un profil sismique vertical. Dans cette mise en oeuvre combinée, la sonde n'est immobilisée que pour le temps d'acquisition du PSV. L'utilisation d'une base sismique réceptrice fixe rend la mise en oeuvre du profil SVP légère et peu onéreuse. Les résultats obtenus montrent que les résolutions verticales du profil SVP et du PSV sont équivalentes. L'investigation latérale de cette mise en oeuvre mixte est de plusieurs centaines de mètres quelle que soit la profondeur. Cette recherche méthodologique a été réalisée en collaboration avec Gaz de France. Increasing the lateral range of investigation of VSP (vertical seismic profiling and the calibration of surface seismic profiles with well geological horizons can be improved by combining a surface seismic profile having a specific implementation (with a fixed receiving base called WVP (well vicinity profiling and a vertical seismic profile. In this combined implementation, the drilling rig is immobilized only for the acquisition time of the VSP. The use of a fixed seismic receiving base makes the implementation of the WVP stack light and inexpensive. The results obtained show that the vertical resolutions of the WVP stack and of the VSP are the same. The lateral range of investigation of this mixed implementation is several hundred meters no matter what the depth may be. This methodological research was done in collaboration with Gaz de France.

  8. On the solar origin of interplanetary disturbances observed in the vicinity of the Earth

    Directory of Open Access Journals (Sweden)

    N. Vilmer

    Full Text Available The solar origin of 40 interplanetary disturbances observed in the vicinity of the Earth between January 1997 and June 1998 is investigated in this paper. Analysis starts with the establishment of a list of Interplanetary Mass Ejections or ICMEs (magnetic clouds, flux ropes and ejecta and of Interplanetary Shocks measured at WIND for the period for which we had previously investigated the coupling of the interplanetary medium with the terrestrial ionospheric response. A search for associated coronal mass ejections (CMEs observed by LASCO/SOHO is then performed, starting from an estimation of the transit time of the inter-planetary perturbation from the Sun to the Earth, assumed to be achieved at a constant speed (i.e. the speed measured at 1 AU. EIT/SOHO and Nançay Radioheliograph (NRH observations are also used as proxies in this identification for the cases when LASCO observations do not allow one to firmly establish the association. The last part of the analysis concerns the identification of the solar source of the CMEs, performed using a large set of solar observations from X-ray to radio wavelengths. In the present study, this association is based on a careful examination of many data sets (EIT, NRH and H images and not on the use of catalogs and of Solar Geophysical Data reports. An association between inter-planetary disturbances and LASCO/CMEs or proxies on the disk is found for 36 interplanetary events. For 32 events, the solar source of activity can also be identified. A large proportion of cases is found to be associated with a flare signature in an active region, not excluding of course the involvement of a filament. Conclusions are finally drawn on the propagation of the disturbances in the interplanetary medium, the preferential association of disturbances detected close to the Earth’s orbit with halos or wide CMEs and the location on the solar disk of solar sources of the interplanetary disturbances during that period

  9. Platinum and associated elements at the New Rambler mine and vicinity, Albany and Carbon Counties, Wyoming

    Science.gov (United States)

    Theobald, P.K.; Thompson, Charles Emmet

    1968-01-01

    Platinum-group metals in the Medicine Bow Mountains were first identified by W. C. Knight in 1901. In the Medicine Bow Mountains, these metals are commonly associated with copper, silver, or gold in shear zones that cut a series of mafic igneous and metamorphic rocks. At the New Rambler mine, where the initial discovery was made, about 50,000 tons of mine and mill waste contain an average of 0.3 percent copper, 7 ppm (parts per million) silver, 1 ppm platinum plus palladium, and 0.7 ppm gold. This material is believed to be from a low-grade envelope around the high-grade pod of complex ore that was mined selectively in the old workings. Soil samples in the vicinity of the New Rambler mine exhibit a wide range of content of several elements associated with the ore. Most of the variation can be attributed to contamination, from the mine workings. Even though soil samples identify a low-level copper anomaly that persists to the limit of the area sampled, soils do not offer a promising medium for tracing mineralization owing to the blanket of transported overburden. Stream sediments, if preconcentrated for analysis, do reveal anomalies not only in the contaminated stream below the New Rambler mine, but in adjacent drainage and on Dave Creek. Examination of a spectrum of elements in heavy-mineral concentrates from stream sediment may contribute to knowledge of the nature of the mineralization and of the basic geology of the environment. The sampling of bedrock exposures is not particularly fruitful because outcrops are sparse and the exposed rocks are the least altered and mineralized. Bedrock sampling does, however, provide information on the large size and provincial nature of the platinum-rich area. We feel that a properly integrated program of geological, geophysical, and geochemical exploration in the Medicine Bow Mountains and probably in the Sierra Madre to the west has a reasonable probability of successfully locating a complex ore body.

  10. Enantioselective Synthesis of Vicinal (R,R)-Diols by Saccharomyces cerevisiae Butanediol Dehydrogenase.

    Science.gov (United States)

    Calam, Eduard; González-Roca, Eva; Fernández, M Rosario; Dequin, Sylvie; Parés, Xavier; Virgili, Albert; Biosca, Josep A

    2016-01-04

    Butanediol dehydrogenase (Bdh1p) from Saccharomyces cerevisiae belongs to the superfamily of the medium-chain dehydrogenases and reductases and converts reversibly R-acetoin and S-acetoin to (2R,3R)-2,3-butanediol and meso-2,3-butanediol, respectively. It is specific for NAD(H) as a coenzyme, and it is the main enzyme involved in the last metabolic step leading to (2R,3R)-2,3-butanediol in yeast. In this study, we have used the activity of Bdh1p in different forms-purified enzyme, yeast extracts, permeabilized yeast cells, and as a fusion protein (with yeast formate dehydrogenase, Fdh1p)-to transform several vicinal diketones to the corresponding diols. We have also developed a new variant of the delitto perfetto methodology to place BDH1 under the control of the GAL1 promoter, resulting in a yeast strain that overexpresses butanediol dehydrogenase and formate dehydrogenase activities in the presence of galactose and regenerates NADH in the presence of formate. While the use of purified Bdh1p allows the synthesis of enantiopure (2R,3R)-2,3-butanediol, (2R,3R)-2,3-pentanediol, (2R,3R)-2,3-hexanediol, and (3R,4R)-3,4-hexanediol, the use of the engineered strain (as an extract or as permeabilized cells) yields mixtures of the diols. The production of pure diol stereoisomers has also been achieved by means of a chimeric fusion protein combining Fdh1p and Bdh1p. Finally, we have determined the selectivity of Bdh1p toward the oxidation/reduction of the hydroxyl/ketone groups from (2R,3R)-2,3-pentanediol/2,3-pentanedione and (2R,3R)-2,3-hexanediol/2,3-hexanedione. In conclusion, Bdh1p is an enzyme with biotechnological interest that can be used to synthesize chiral building blocks. A scheme of the favored pathway with the corresponding intermediates is proposed for the Bdh1p reaction. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  11. An unusually very bright dust light mass (?) observed in the vicinity (?) of á Lyrae

    Science.gov (United States)

    Stefanopoulos, G.

    2009-04-01

    directed to the astrophysics society to give a rational explanation of this unexplain to us phenomenon. What conditions and forces influence the liberation of such dust or possible charged aerosols? In our planet we have similar phenomena of aerosols liberation from earth mantel. As an explanation, the case of a comet or asteroid or satellite,is exluded. Are they finally a case of γ ray burst? Key point question remains, how to trap the portion of possible rotating dust in the vicinity of the star, in a conventional (in a ten minutes exposure) photogram. Would the scientist experts please reply to this question and clarify the reason.

  12. [Faunal characteristics and distribution pattern of crustaceans in the vicinity of Pearl River estuary].

    Science.gov (United States)

    Huang, Zi-Rong; Sun, Dian-Rong; Chen, Zuo-Zhi; Zhang, Han-Hua; Wang, Xue-Hui; Wang, Yue-Zhong; Fang, Hong-Da; Dong, Yan-Hong

    2009-10-01

    Based on the data of bottom trawl surveys in the vicinity of Pearl River estuary in August (summer), October (autumn), December (winter) 2006, and April (spring) 2007, the faunal characteristics and distribution pattern of crustaceans were analyzed. A total of 54 species belonging to 25 genera, 17 families, and 2 orders were collected, including 22 species of shrimps, 22 species of crabs, and 10 species of squills. Most of the crustaceans were tropical-subtropical warm-water species, a few of them were eurythermal species, and no warm-water and cold-water species occurred. Euryhaline species were most abundant, followed by halophile species, and the low-salinity species were the least. Most of the crustacean species belonged to the fauna of Indian Ocean-western Pacific Ocean. The faunal assemblages were closer to those of the East China Sea, Philippine Sea, Indonesia Sea, and the Japan Sea, and estranger with those of the Yellow Sea, Bohai Sea, and Korea Sea. The dominant species were Metapenaeus joyner, Oratosquilla oratoria, Charybdis miles, Portunus sanguinolentus, Harpiosquilla harpax, Charybdis feriatus, Charybdis japonica, Oratosquilla nepa, Solenocera crassicornis, Portunus trituberculatus, and Calappa philargius. The crustaceans had the largest species number (33) in autumn and the least one (26) in spring, and the highest stock density at the water depth of < 40 m, especially at 10-20 m. The average stock density of the crustaceans was estimated to be 99.60 kg x km(-2), with the highest (198.93 kg x km(-2)) in summer and the lowest (42.35 kg x km(-2)) in spring. Of the 3 species groups, crabs had the highest stock density (41.81 kg x km(-2)), followed by shrimps (38.91 kg x km(-2)), and squills (18.88 kg x km(-2)). The stock densities of the 3 species groups showed an obvious seasonal variation. Shrimps had the highest stock density (120.32 kg x km(-2)) in summer and the lowest density (0.67 kg x km(-2)) in spring, while crabs and squills had the highest

  13. Lead accumulation by some plant species cultivated in the vicinity of a lead factory in Sfax; Accumulation du plomb par quelques especes vegetales cultivees au voisinage d'une fonderie de plomb a Sfax

    Energy Technology Data Exchange (ETDEWEB)

    Elloumi, N.; Ben Abdallah, F.; Mezghani, I.; Boukhris, M. [Faculte des Sciences de Sfax, Lab. d' Ecologie Vegetale, Unite de Recherche Biologie de la Vegetation en Milieu Aride, Sfax (Tunisia)

    2003-06-01

    Atmospheric emissions, particularly the particles containing high concentrations of heavy metals, have harmful effects on the environment. The aim of this work is to evaluate the accumulation of a lead factory emissions, on the vegetation near the factory in function of time, distance and climatic factors. Analyses results have showed an important lead accumulation by vegetation located in the vicinity of the factory. Plant species studied here (olive trees, palm trees, almond trees, pomegranate trees and vine) have shown high and variable lead accumulation. Highest concentrations (over than 400 {mu}g/g) were recorded in non-washed leaves of olive trees surrounding the factory. Rapid and considerable decrease of lead content was, however, recorded for the same species situated at a distance bigger than 1 km from the source. Interaction effects study of several factors, such as climatic factors and diversity of plant species on lead accumulation by plants, have shown that the degree of lead accumulation was related to wind direction and distance from pollution source. Lead concentrations in species planted in the NW of the factory and exposed to SE wind direction were higher than that of ones exposed to any other direction. High lead concentrations in the vicinity of the factory seem to indicate that particles and gaseous pollutants fallout in the surrounding of the factory are as much important as the chimney height is reduced. (authors)

  14. Salt marshes of Port Valdez, Alaska, and vicinity: A baseline study: Final report to the United States Department of the Interior

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In 1974 and 1975, 62 baseline locations were selected for intensive study in the salt marshes of Port Valdez and vicinity. The sites are intended to reflect the...

  15. Community Structure of Fish and Macrobenthos at Selected Sites in the Vicinity of Mokapu Ocean Outfall, Oahu, Hawaii, 1998 (NODC Accession 0000173)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This report provides the results of the first quantitative survey of the coral reef communities in the vicinity of the Mokapu Ocean Outfall in Kailua Bay, Oahu,...

  16. Lagrangian Observations of Nonlinear Internal Waves and Turbulence Mixing in Luzon Strait and South China Sea and Internal Wave in the Vicinity of the Kuroshio Path

    National Research Council Canada - National Science Library

    Lien, Ren-Chieh; D'Asaro, Eric A

    2008-01-01

    ... mixing in the northern South China Sea. Results are reported. The second was to analyze observations of data taken in the vicinity of the Kuroshio path from Luzon Strait to the southern East China Sea...

  17. Fuzzy neuronal model of motor control inspired by cerebellar pathways to online and gradually learn inverse biomechanical functions in the presence of delay.

    Science.gov (United States)

    Salimi-Badr, Armin; Ebadzadeh, Mohammad Mehdi; Darlot, Christian

    2017-10-09

    Contrary to forward biomechanical functions, which are deterministic, inverse biomechanical functions are generally not. Calculating an inverse biomechanical function is an ill-posed problem, which has no unique solution for a manipulator with several degrees of freedom. Studies of the command and control of biological movements suggest that the cerebellum takes part in the computation of approximate inverse functions, and this ability can control fast movements by predicting the consequence of current motor command. Limb movements toward a goal are defined as fast if they last less than the total duration of the processing and transmission delays in the motor and sensory pathways. Because of these delays, fast movements cannot be continuously controlled in a closed loop by use of sensory signals. Thus, fast movements must be controlled by some open loop controller, of which cerebellar pathways constitute an important part. This article presents a system-level fuzzy neuronal motor control circuit, inspired by the cerebellar pathways. The cerebellar cortex (CC) is assumed to embed internal models of the biomechanical functions of the limb segments. Such neural models are able to predict the consequences of motor commands and issue predictive signals encoding movement variables, which are sent to the controller via internal feedback loops. Differences between desired and expected values of variables of movements are calculated in the deep cerebellar nuclei (DCN). After motor learning, the whole circuit can approximate the inverse function of the biomechanical function of a limb and acts as a controller. In this research, internal models of direct biomechanical functions are learned and embedded in the connectivity of the cerebellar pathways. Two fuzzy neural networks represent the two parts of the cerebellum, and an online gradual learning drives the acquisition of the internal models in CC and the controlling rules in DCN. As during real learning, exercise and

  18. Landsat with SRTM Shaded Relief, Los Angeles and Vicinity from Space

    Science.gov (United States)

    2002-01-01

    Los Angeles and vicinity seen from space, as viewed by the Landsat 7 satellite from an altitude of 437 miles on May 4, 2001. North is at the top. Topographic shading has been enhanced using an elevation data set acquired by the Space Shuttle Endeavour in February 2000. Downtown Los Angeles is just south of the image center, with L.A. and Long Beach harbors to the south, Santa Monica Bay to the west, San Fernando Valley to the northwest, San Gabriel Valley to the east, and Orange County to the southeast. The San Andreas fault forms the straight diagonal mountain front bordering the Mojave Desert at the top of the image. At full resolution, features on the ground as small as 15 meters (49 feet) across can be distinguished, including street patterns and large buildings, as well as boats and their wakes on the ocean. More than ten million people live within this scene.This image was generated by first geographically matching the Landsat scene to a Shuttle Radar Topography Mission (SRTM) elevation model. A measure of topographic slope along a southeast-northwest trend was then calculated, such that southeast facing slopes appear bright and northwest facing slopes appear dark. This slope image was then added to the enhanced Landsat scene in order to intensify the appearance of topography. Topographic shading was subtle in the original Landsat scene due to the fairly high sun angle (63 degrees above the horizon) during the satellite overflight in late morning of a mid-Spring day.Landsat has been providing visible and infrared views of the Earth since 1972. SRTM elevation data matches the 30-meter (98-foot) resolution of most Landsat images and helps in analyzing the large and growing Landsat image archive, managed by the U.S. Geological Survey (USGS).Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne

  19. Public health risk assessment with bioaccessibility considerations for soil PAHs at oil refinery vicinity areas in India.

    Science.gov (United States)

    Tarafdar, Abhrajyoti; Sinha, Alok

    2017-10-21

    Populations living in the vicinity of oil refinery sludge deposition sites may be at greater risk of potential exposure to polycyclic aromatic hydrocarbons (PAHs) through inhalation, ingestion, and direct contact with contaminated media. Three Indian oil refinery sludge deposition sites (at Haldia, Barauni and Guwahati) were chosen for study. Soil samples were collected from three different locations at each site. Mild solvent extraction by butanol and exhaustive extraction by acetone/hexane have been conducted to estimate the bioaccessible PAHs beside the total extractable PAHs content of the soil samples. Concentrations of 13 PAHs in the soils were found to be in a range of 67.02-95.21μg/g and bioaccessible PAHs were in a range of 19.296-36.657μg/g. A probabilistic health risk assessment with bioaccessibility considerations was carried out using Monte Carlo simulations for the estimation of the cancer risk exposed to the PAHs. The 90th percentiles cancer risks with bioaccessibility considerations of soil PAHs for children is 6.506E-05 and for the adults the risk is 6.609E-05. Risk assessments on extracted PAHs from exhaustive solvent extraction can overestimate the risk by 2.87-2.89 folds at 90% confidence level with respect to the biomimetic mild extraction procedure using butanol. According to USEPA above 1×10(-6) extra risk of cancer is an alarm towards management. So, public health issues due to PAHs is imminent in these oil refinery vicinity areas. Sensitivity analysis revealed exposure duration (ED) and relative skin adherence factor for soil (AF) as the most influential parameters of the assessment. The profiling and risk assessment study with bioaccessibility considerations of PAHs from soil indicates that high PAHs concentration can lead to higher cancer risk for the vicinity area residents and local government should take immediate management actions. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Visual impairment and blindness among the students of blind schools in Allahabad and its vicinity: A causal assessment

    Directory of Open Access Journals (Sweden)

    Sushank Ashok Bhalerao

    2015-01-01

    Full Text Available Background/Aims: Information on eye diseases in blind school children in Allahabad is rare and sketchy. A cross-sectional study was performed to identify causes of blindness (BL in blind school children with an aim to gather information on ocular morbidity in the blind schools in Allahabad and in its vicinity. Study Design and Setting: A cross-sectional study was carried out in all the four blind schools in Allahabad and its vicinity. Materials and Methods: The students in the blind schools visited were included in the study and informed consents from parents were obtained. Relevant ocular history and basic ocular examinations were carried out on the students of the blind schools. Results: A total of 90 students were examined in four schools of the blind in Allahabad and in the vicinity. The main causes of severe visual impairment and BL in the better eye of students were microphthalmos (34.44%, corneal scar (22.23%, anophthalmos (14.45%, pseudophakia (6.67%, optic nerve atrophy (6.67%, buphthalmos/glaucoma (3.33%, cryptophthalmos (2.22%, staphyloma (2.22%, cataract (2.22%, retinal dystrophy (2.22%, aphakia (1.11%, coloboma (1.11%, retinal detachment (1.11%, etc. Of these, 22 (24.44% students had preventable causes of BL and another 12 (13.33% students had treatable causes of BL. Conclusion: It was found that hereditary diseases, corneal scar, glaucoma and cataract were the prominent causes of BL among the students of blind schools. Almost 38% of the students had preventable or treatable causes, indicating the need of genetical counseling and focused intervention.

  1. Visual impairment and blindness among the students of blind schools in Allahabad and its vicinity: A causal assessment.

    Science.gov (United States)

    Bhalerao, Sushank Ashok; Tandon, Mahesh; Singh, Satyaprakash; Dwivedi, Shraddha; Kumar, Santosh; Rana, Jagriti

    2015-03-01

    Information on eye diseases in blind school children in Allahabad is rare and sketchy. A cross-sectional study was performed to identify causes of blindness (BL) in blind school children with an aim to gather information on ocular morbidity in the blind schools in Allahabad and in its vicinity. A cross-sectional study was carried out in all the four blind schools in Allahabad and its vicinity. The students in the blind schools visited were included in the study and informed consents from parents were obtained. Relevant ocular history and basic ocular examinations were carried out on the students of the blind schools. A total of 90 students were examined in four schools of the blind in Allahabad and in the vicinity. The main causes of severe visual impairment and BL in the better eye of students were microphthalmos (34.44%), corneal scar (22.23%), anophthalmos (14.45%), pseudophakia (6.67%), optic nerve atrophy (6.67%), buphthalmos/glaucoma (3.33%), cryptophthalmos (2.22%), staphyloma (2.22%), cataract (2.22%), retinal dystrophy (2.22%), aphakia (1.11%), coloboma (1.11%), retinal detachment (1.11%), etc. Of these, 22 (24.44%) students had preventable causes of BL and another 12 (13.33%) students had treatable causes of BL. It was found that hereditary diseases, corneal scar, glaucoma and cataract were the prominent causes of BL among the students of blind schools. Almost 38% of the students had preventable or treatable causes, indicating the need of genetical counseling and focused intervention.

  2. Single quantum dot spectroscopy of CdSe/ZnSe grown on vicinal GaAs substrates

    Science.gov (United States)

    Makino, T.; André, R.; Gérard, J.-M.; Romestain, R.; Dang, Le Si; Bartels, M.; Lischka, K.; Schikora, D.

    2003-04-01

    We investigated the optical properties of two monolayers of CdSe sandwiched by ZnSe layers grown by molecular-beam epitaxy on GaAs substrates with a vicinal tilt of 2° in the [111] direction. By varying the spatial resolution from 10 μm down to 500 nm, sharp photoluminescence lines due to the recombination of excitons confined into quantum dots could be observed at low temperature. The dot density could be as low as ≈109 dots/cm2, which is smaller than previously reported values by at least one order of magnitude.

  3. Geophysical studies in the vicinity of Blue Mountain and Pumpernickel Valley near Winnemucca, north-central Nevada

    Science.gov (United States)

    Ponce, David A.

    2012-01-01

    From May 2008 to September 2009, the U.S. Geological Survey (USGS) collected data from more than 660 gravity stations, 100 line-km of truck-towed magnetometer traverses, and 260 physical-property sites in the vicinity of Blue Mountain and Pumpernickel Valley, northern Nevada (fig. 1). Gravity, magnetic, and physical-property data were collected to study regional crustal structures as an aid to understanding the geologic framework of the Blue Mountain and Pumpernickel Valley areas, which in general, have implications for mineral- and geothermal-resource investigations throughout the Great Basin.

  4. Content of metals and metabolites in honey originated from the vicinity of industrial town Kosice (eastern Slovakia)

    OpenAIRE

    Kováčik, J.; Grúz, J. (Jiří); Bíba, O. (Ondřej); Hedbavny, J.

    2016-01-01

    Composition of three types of honey (mixed forest honey and monofloral-black locust and rapeseed honeys) originated from the vicinity of an industrial town (Kosice, Slovak Republic) was compared. Higher content of minerals including toxic metals in forest honey (1358.6 ng Ni/g, 85.6 ng Pb/g, and 52.4 ng Cd/g) than in rapeseed and black locust honeys confirmed that botanical origin rather than the distance for eventual source of pollution (steel factory) affects metal deposition. Benzoic acid ...

  5. Odd-parity superconductivity in the vicinity of inversion symmetry breaking in spin-orbit-coupled systems

    Science.gov (United States)

    Kozii, Vladyslav; Fu, Liang; Massachusetts institute of technology Team

    We study superconductivity in spin-orbit-coupled systems in the vicinity of inversion symmetry breaking. We find that due to the presence of spin-orbit coupling, fluctuations of the incipient parity-breaking order generate an attractive pairing interaction in an odd-parity pairing channel, which competes with the s-wave pairing. We show that Coulomb repulsion or an external Zeeman field suppresses the s-wave pairing and promotes the odd-parity superconducting state. Our work provides a new mechanism for odd-parity pairing and opens a route to novel topological superconductivity. This work is supported by the David and Lucile Packard foundation.

  6. Data on metals biomonitoring in the body of schoolchildren in the vicinity of a heavily industrialized site

    Directory of Open Access Journals (Sweden)

    Raheleh Kafaei

    2017-06-01

    Full Text Available This data is obtained from analyzing the concentration of metals include Al, Co, Cr, Cu, Fe, Mo, Pb, and Zn in the urine of schoolchildren in Asalouyeh city in vicinity to a heavily industrialized site and comparison with a reference city. The significance of sex groups on urine metal level was evaluated through this data. The urinary content of metals was measured by inductively coupled plasma atomic emission spectroscopy (ICP-OES. Statistical analyze of data were done by Mann–Whitney test. The herein presented date could beneficial for health assessment of gas and petrochemical companies.

  7. Longtime radionuclide monitoring in the vicinity of Salaspils nuclear reactor; Dauerhaftes Monitoring der Radionuklide in Umgebung von Salaspils Kernreaktor

    Energy Technology Data Exchange (ETDEWEB)

    Riekstina, D.; Berzins, J.; Krasta, T. [Latvia Univ. (Latvia). Inst. of Solid State Physics; Skrypnik, O.; Alksnis, J. [Latvia Univ. (Latvia). Inst. of Chemical Physics

    2016-07-01

    The research nuclear reactor in Salaspils was decommissioned in 1998. Now reactor is partially dismantled and its territory is used as a temporary storage of radioactivity contaminated materials and water. Environment radioactivity monitoring for presence of artificial radionuclides in the vicinity of Salaspils nuclear reactor is carried out since 1990. Data include Cs-137 concentration in soils, tritium concentration in ground water, as well as H-3, Cs-137, Co-60 concentration and gross beta-activity of reactors sewage and rainwater drainage. The systematic monitoring allowed to detect in December 2014 a leakage from the special wastewater basin and so to prevent a pollution of ground water outside reactors territory.

  8. Analytical results for 544 water samples collected in the Attean Quartz Monzonite in the vicinity of Jackman, Maine

    Science.gov (United States)

    Ficklin, W.H.; Nowlan, G.A.; Preston, D.J.

    1983-01-01

    Water samples were collected in the vicinity of Jackman, Maine as a part of the study of the relationship of dissolved constituents in water to the sediments subjacent to the water. Each sample was analyzed for specific conductance, alkalinity, acidity, pH, fluoride, chloride, sulfate, phosphate, nitrate, sodium, potassium, calcium, magnesium, and silica. Trace elements determined were copper, zinc, molybdenum, lead, iron, manganese, arsenic, cobalt, nickel, and strontium. The longitude and latitude of each sample location and a sample site map are included in the report as well as a table of the analytical results.

  9. Palladium-catalyzed vicinal amino alcohols synthesis from allyl amines by in situ tether formation and carboetherification.

    Science.gov (United States)

    Orcel, Ugo; Waser, Jerome

    2015-04-20

    Vicinal amino alcohols are important structural motifs of bioactive compounds. Reported herein is an efficient method for their synthesis based on the palladium-catalyzed oxy-alkynylation, oxy-arylation, or oxy-vinylation of allylic amines. High regio- and stereoselectivity were ensured through the in situ formation of a hemiaminal tether using the cheap commercially available trifluoroacetaldehyde in its hemiacetal form. The obtained compounds are important building blocks, which can be orthogonally deprotected to give either free alcohols, amines, or terminal alkynes. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Toward lifetime and g factor measurements of short-lived states in the vicinity of 208Pb

    Science.gov (United States)

    Ralet, D.; Georgiev, G.; E Stuchbery, A.; Clément, E.; Lemasson, A.; Michelagnoli, C.; Rejmund, M.; Atanasova, L.; Balabanski, D. L.; Bocchi, G.; Carroll, R.; Dewald, A.; Dudouet, J.; Fornal, B.; de France, G.; Franchoo, S.; Fransen, C.; Müller-Gatermann, C.; Goasduff, A.; Gadea, A.; Jacquot, B.; John, P. R.; Kocheva, D.; Konstantinopoulos, T.; Korichi, A.; Kusoglu, A.; Lenzi, S. M.; Leoni, S.; Ljungvall, J.; Lozeva, R.; Maj, A.; Navin, A.; Perez, R.; Pietralla, N.; Shand, C.; Stezowski, O.; Yordanov, D.

    2017-05-01

    The multi-nucleon transfer reaction mechanism was used to produce and study nuclei in the vicinity of 208Pb. This mass region is a test case for the nuclear shell model. The mass identification of the fragments was performed with the large acceptance magnetic spectrometer VAMOS++ coupled to the AGATA γ-tracking array. This experiment aimed to determine both lifetimes and gyromagnetic ratios of excited states with the Cologne plunger device. The analysis indicates promising results with the possibility to determine several new lifetimes in this region.

  11. Geomorphic processes in the vicinity of the Venkatapur river mouth, central west coast of India: Implications for estuarine sedimentation

    Digital Repository Service at National Institute of Oceanography (India)

    Nayak, S.R.; Hegde, V.S.; Shalini, G.; Rajawat, A.S.; Girish, K.H.; Jayakumar, S.; Suryanarayana, A.

    of the Venkatapur River mouth, central west coast of India: Implications for estuarine sedimentation. Journal of Coastal Research, 26(5), 925–934. West Palm Beach (Florida), ISSN 0749-0208. We discuss geomorphic processes in the vicinity of river mouths... loads of the rivers, along with the littoral drift due to wave action (Reddy, Hariharan, and Kurian, 1979). In New Mangalore port, it is mainly due to deposition of seabed material brought into suspension by the monsoon waves (Dattatri and Kamath, 1997...

  12. Water-level data from wells in the vicinity of the Waste Isolation Pilot Plant, southeastern New Mexico

    Science.gov (United States)

    Richey, S.F.

    1987-01-01

    The U.S. Geological Survey monitored water levels in wells in the vicinity of the Waste Isolation Pilot Plant, a storage facility constructed in bedded salts in which defense-associated transuranic wastes will be deposited, in southeastern New Mexico during 1977 to 1985. A variety of methods was used to measure water levels. The particular method utilized at a given time depended on several factors, including the amount of condensation in the well, well-head configuration, depth to water, rate of water level change, and availability of equipment. The five methods utilized were: air line, Lynes pressure sentry system, M-scope, steel tape, and winch. (Lantz-PTT)

  13. A contribution to the Encarsia and Eretmocerus (Hymenoptera: Aphelinidae species from the Arasbaran biosphere reserve and vicinity, northwestern Iran

    Directory of Open Access Journals (Sweden)

    Ghahari Hassan

    2011-01-01

    Full Text Available The fauna of the Encarsia and Eretmocerus species (Hymenoptera: Chalcidoidea: Aphelinidae from Arasbaran and its vicinity (Northwestern Iran is studied in this paper. A total of 16 Encarsia species, including E. acaudaleyrodis Hayat, E. aleurochitonis (Mercet, E. aurantii (Howard, E. azimi Hayat, E. berlesei (Howard, E. citrina (Craw, E. elegans (Masi, E. elongata (Dozier, E. fasciata (Malenotti, E. formosa Gahan, E. inaron (Walker, E. lounsburyi (Berlese and Paoli, E. lutea (Masi, E. luteola Howard, E. mineoi Viggiani, E. perniciosi (Tower, and 4 Eretmocerus species (Eretmocerus cadabae Viggiani, Eretmocerus mundus Mercet, Eretmocerus nikolskajae Myartseva, Eretmocerus serius Silvestre were collected.

  14. Decreased serum bilirubin is associated with arterial stiffness in men.

    Science.gov (United States)

    Li, Y; Meng, S-y; Meng, C-c; Yu, W-g; Wang, R-t

    2013-04-01

    The brachial-ankle pulse wave velocity (baPWV) is a marker for early atherosclerotic changes. Serum total bilirubin (TB) is an effective antioxidant and has been associated with carotid intima-media thickness, cardiovascular disease, stroke and peripheral arterial disease, all of which may be caused by arteriosclerosis. This study aimed to investigate the association of TB with arterial stiffness. In this cross-sectional study, we investigated the relationship between TB and baPWV in 2207 participants (1331 men, 876 women) in a general health examination. Different metabolic parameters were compared across TB quartiles. Age-adjusted mean values of baPWV gradually decreased with TB quartiles in men (Q1 = 1348, Q2 = 1266, Q3 = 1215, and Q4 = 1154 cm/s). However, the age-adjusted means of baPWV had no significance in women according to TB quartiles. Univariate analysis showed that age, smoking status, BMI, SBP, DBP, AST, ALT, GGT, TB, TG, and HDL-C were significantly associated with baPWV in men, whereas only age, BMI, SBP, DBP, TG and FPG were significantly associated with baPWV in women. In addition, BMI, SBP, TB, age, TG, and AST were significant factors in the multivariate model with baPWV in men; only BMI and FPG were significant factors with baPWV in women. The findings show that serum total bilirubin concentration is negatively correlated to arterial stiffness in Chinese men. Early detection of abnormal bilirubin levels could potentially serve as an early biomarker for arterial stiffness. Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.

  15. Enhanced microalgal biomass and lipid production from a consortium of indigenous microalgae and bacteria present in municipal wastewater under gradually mixotrophic culture conditions.

    Science.gov (United States)

    Cho, Hyun Uk; Kim, Young Mo; Park, Jong Moon

    2017-03-01

    The goal of this study was to investigate the influences of gradually mixotrophic culture conditions on microalgal biomass and lipid production by a consortium of indigenous microalgae and bacteria present in raw municipal wastewater. Lab-scale photobioreactors containing the consortium were operated in repeated batch mode. Initial cultivation (phase I) was performed using only the municipal wastewater, then 10% and 25% of the reactor volumes were replaced with the effluent from a sewage sludge fermentation system producing volatile fatty acids (SSFV) at the beginnings of phase II and phase III, respectively. The highest biomass productivity (117.1±2.7mg/L/d) was attained during phase II, but the lipid productivity (17.2±0.2mg/L/d) was attained during phase III. The increase in the effluent from the SSFV influenced microalgal diversity with a preference for Chlorella sp., but bacterial diversity increased significantly during phase III. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. From aquatic to terrestrial food webs: decrease of the docosahexaenoic acid/linoleic acid ratio.

    Science.gov (United States)

    Koussoroplis, Apostolos-Manuel; Lemarchand, Charles; Bec, Alexandre; Desvilettes, Christian; Amblard, Christian; Fournier, Christine; Berny, Philippe; Bourdier, Gilles

    2008-05-01

    Fatty acid composition of the adipose tissue of six carnivorous mammalian species (European otter Lutra lutra, American mink Mustela vison, European Mink Mustela lutreola, European polecat Mustela putorius, stone marten Martes foina and European wild cat Felis silvestris) was studied. These species forage to differing degrees in aquatic and terrestrial food webs. Fatty acid analysis revealed significant differences in polyunsaturated fatty acid composition between species. More specifically, our results underline a gradual significant decrease in the docosahexaenoic acid (DHA)/linoleic acid (LNA) ratio of carnivore species as their dependence on aquatic food webs decreases. In conclusion, the use of the DHA/LNA ratio in long-term studies is proposed as a potential proxy of changes in foraging behaviour of semi-aquatic mammals.

  17. Sudden collapse of vacuoles in Saintpaulia sp. palisade cells induced by a rapid temperature decrease.

    Science.gov (United States)

    Kadohama, Noriaki; Goh, Tatsuaki; Ohnishi, Miwa; Fukaki, Hidehiro; Mimura, Tetsuro; Suzuki, Yoshihiro

    2013-01-01

    It is well known that saintpaulia leaf is damaged by the rapid temperature decrease when cold water is irrigated onto the leaf surface. We investigated this temperature sensitivity and the mechanisms of leaf damage in saintpaulia (Saintpaulia sp. cv. 'Iceberg') and other Gesneriaceae plants. Saintpaulia leaves were damaged and discolored when subjected to a rapid decrease in temperature, but not when the temperature was decreased gradually. Sensitivity to rapid temperature decrease increased within 10 to 20 min during pre-incubation at higher temperature. Injury was restricted to the palisade mesophyll cells, where there was an obvious change in the color of the chloroplasts. During a rapid temperature decrease, chlorophyll fluorescence monitored by a pulse amplitude modulated fluorometer diminished and did not recover even after rewarming to the initial temperature. Isolated chloroplasts were not directly affected by the rapid temperature decrease. Intracellular pH was monitored with a pH-dependent fluorescent dye. In palisade mesophyll cells damaged by rapid temperature decrease, the cytosolic pH decreased and the vacuolar membrane collapsed soon after a temperature decrease. In isolated chloroplasts, chlorophyll fluorescence declined when the pH of the medium was lowered. These results suggest that a rapid temperature decrease directly or indirectly affects the vacuolar membrane, resulting in a pH change in the cytosol that subsequently affects the chloroplasts in palisade mesophyll cells. We further confirmed that the same physiological damage occurs in other Gesneriaceae plants. These results strongly suggested that the vacuoles of palisade mesophyll cells collapsed during the initial phase of leaf injury.

  18. Sudden collapse of vacuoles in Saintpaulia sp. palisade cells induced by a rapid temperature decrease.

    Directory of Open Access Journals (Sweden)

    Noriaki Kadohama

    Full Text Available It is well known that saintpaulia leaf is damaged by the rapid temperature decrease when cold water is irrigated onto the leaf surface. We investigated this temperature sensitivity and the mechanisms of leaf damage in saintpaulia (Saintpaulia sp. cv. 'Iceberg' and other Gesneriaceae plants. Saintpaulia leaves were damaged and discolored when subjected to a rapid decrease in temperature, but not when the temperature was decreased gradually. Sensitivity to rapid temperature decrease increased within 10 to 20 min during pre-incubation at higher temperature. Injury was restricted to the palisade mesophyll cells, where there was an obvious change in the color of the chloroplasts. During a rapid temperature decrease, chlorophyll fluorescence monitored by a pulse amplitude modulated fluorometer diminished and did not recover even after rewarming to the initial temperature. Isolated chloroplasts were not directly affected by the rapid temperature decrease. Intracellular pH was monitored with a pH-dependent fluorescent dye. In palisade mesophyll cells damaged by rapid temperature decrease, the cytosolic pH decreased and the vacuolar membrane collapsed soon after a temperature decrease. In isolated chloroplasts, chlorophyll fluorescence declined when the pH of the medium was lowered. These results suggest that a rapid temperature decrease directly or indirectly affects the vacuolar membrane, resulting in a pH change in the cytosol that subsequently affects the chloroplasts in palisade mesophyll cells. We further confirmed that the same physiological damage occurs in other Gesneriaceae plants. These results strongly suggested that the vacuoles of palisade mesophyll cells collapsed during the initial phase of leaf injury.

  19. Effects of trophic conditions on benthic macrofauna in the vicinity of the River Swina mouth (Pomeranian Bay; southern Baltic Sea

    Directory of Open Access Journals (Sweden)

    Jerzy Masłowski

    2003-03-01

    Full Text Available The export of phytal material from the eutrophic Szczecin Lagoon into the Pomeranian Bay creates excellent trophic conditions forthe local benthic fauna in the vicinity of the mouth of the river Swina, where the bottom macrofauna is abundant but highly variable.The changes in the bottom macrofauna biomass of selected taxa, chlorophyll a and nutrient concentrations were tested for associations. The biomasses of selected taxa varied in significant concordance, which suggests that these changes have common causes.Despite the importance of trophic enrichment to faunal abundance, no relationships between faunal biomass and chlorophyll a concentration changes were established. The presence of organic matter enables macrofauna to attain a high biomass, but populationfluctuations are controlled by numerous factors. The significant relationship between the changes in the annual averagephosphate levels and chlorophyll a concentrations in the Szczecin Lagoon indicates the importance of this nutrient to primaryproduction processes in the Lagoon and to the trophic conditions for benthic macrofauna in the vicinity of the Swina mouth.

  20. Sediment porewater toxicity assessment studies in the vicinity of offshore oil and gas production platforms in the Gulf of Mexico

    Science.gov (United States)

    Carr, R.S.; Chapman, D.C.; Presley, B.J.; Biedenbach, J.M.; Robertson, L.; Boothe, P.; Kilada, R.; Wade, T.; Montagna, P.

    1996-01-01

    As part of a multidisciplinary program to assess the potential long-term impacts of offshore oil and gas exploration and production activities in the Gulf of Mexico, sediment chemical analyses and porewater toxicity tests were conducted in the vicinity of five offshore platforms. Based on data from sea urchin fertilization and embryological development assays, toxicity was observed near four of the five platforms sampled; the majority of the toxic samples were collected within 150 m of a platform. There was excellent agreement among the results of porewater tests with three different species (sea urchin embryological development, polychaete reproduction, and copepod nauplii survival). The sediment concentrations of several metals were well in excess of sediment quality assessment guidelines at a number of stations, and good agreement was observed between predicted and observed toxicity. Porewater metal concentrations compared with EC50, LOEC, and NOEC values generated for water-only exposures indicated that the porewater concentrations for several metals were high enough to account for the observed toxicity. Results of these studies utilizing highly sensitive toxicity tests suggest that the contaminant-induced impacts from offshore platforms are limited to a localized area in the immediate vicinity of the platforms. 

  1. Solid-tumor mortality in the vicinity of uranium cycle facilities and nuclear power plants in Spain.

    Science.gov (United States)

    López-Abente, G; Aragonés, N; Pollán, M

    2001-07-01

    To ascertain solid tumor mortality in towns near Spain's four nuclear power plants and four nuclear fuel facilities from 1975 to 1993, we conducted a mortality study based on 12,245 cancer deaths in 283 towns situated within a 30-km radius of the above installations. As nonexposed areas, we used 275 towns lying within a 50- to 100-km radius of each installation, matched by population size and sociodemographic characteristics (income level, proportion of active population engaged in farming, proportion of unemployed, percentage of illiteracy, and province). Using log-linear models, we examined relative risk for each area and trends in risk with increasing proximity to an installation. The results reveal a pattern of solid-tumor mortality in the vicinity of uranium cycle facilities, basically characterized by excess lung [relative risk (RR) 1.12, 95% confidence interval (CI), 1.02-1.25] and renal cancer mortality (RR 1.37, 95% CI, 1.07-1.76). Besides the effects of natural radiation, these results could well be evincing the influence on public health exerted by the environmental impact of mining. No such well-defined pattern appeared in the vicinity of nuclear power plants. Monitoring of cancer incidence and mortality is recommended in areas surrounding nuclear fuel facilities and nuclear power plants, and more specific studies are called for in areas adjacent to installations that have been fully operational for longer periods. In this regard, it is important to use dosimetric information in all future studies.

  2. Analysis of snow-cap pollution for air quality assessment in the vicinity of an oil refinery.

    Science.gov (United States)

    Krastinyte, Viktorija; Baltrenaite, Edita; Lietuvninkas, Arvydas

    2013-01-01

    Snow-cap can be used as a simple and effective indicator of industrial air pollution. In this study snow-cap samples were collected from 11 sites located in the vicinity of an oil refinery in Mazeikiai, a region in the north-west of Lithuania, in the winter of 2011. Analysis of snowmelt water and snow-dust was used to determine anthropogenic pollutants such as: sulphates and chlorides, nitrites, nitrates, ammonium nitrogen, total carbon, total nitrogen; heavy metals: lead (Pb), copper (Cu), chromium (Cr), cadmium (Cd). Concentrations of heavy metals in snow-dust were detected thousands of times higher than those in the snowmelt water. In this study, analysis of heavy metal concentration was conducted considering different distances and the wind direction within the impact zone of the oil refinery. The sequence of heavy metals according to their mean concentrations in the snow-dust samples was the following: Pb > Cr > Cu > Cd. Heavy metals highly correlated among each other. The load of snow-dust was evaluated to determine the pollution level in the study area. The highest daily load of snow-dust was 45.81 +/- 12.35 mg/m2 in the north-western direction from the oil refinery. According to classification of the daily load of snow-dust a lower than medium-risk level of pollution was determined in the vicinity of the oil refinery.

  3. Digital Geologic Map of the Nevada Test Site and Vicinity, Nye, Lincoln, and Clark Counties, Nevada, and Inyo County, California

    Science.gov (United States)

    Slate, Janet L.; Berry, Margaret E.; Rowley, Peter D.; Fridrich, Christopher J.; Morgan, Karen S.; Workman, Jeremiah B.; Young, Owen D.; Dixon, Gary L.; Williams, Van S.; McKee, Edwin H.; Ponce, David A.; Hildenbrand, Thomas G.; Swadley, W.C.; Lundstrom, Scott C.; Ekren, E. Bartlett; Warren, Richard G.; Cole, James C.; Fleck, Robert J.; Lanphere, Marvin A.; Sawyer, David A.; Minor, Scott A.; Grunwald, Daniel J.; Laczniak, Randell J.; Menges, Christopher M.; Yount, James C.; Jayko, Angela S.

    1999-01-01

    This digital geologic map of the Nevada Test Site (NTS) and vicinity, as well as its accompanying digital geophysical maps, are compiled at 1:100,000 scale. The map compilation presents new polygon (geologic map unit contacts), line (fault, fold axis, metamorphic isograd, dike, and caldera wall) and point (structural attitude) vector data for the NTS and vicinity, Nye, Lincoln, and Clark Counties, Nevada, and Inyo County, California. The map area covers two 30 x 60-minute quadrangles-the Pahute Mesa quadrangle to the north and the Beatty quadrangle to the south-plus a strip of 7.5-minute quadrangles on the east side-72 quadrangles in all. In addition to the NTS, the map area includes the rest of the southwest Nevada volcanic field, part of the Walker Lane, most of the Amargosa Desert, part of the Funeral and Grapevine Mountains, some of Death Valley, and the northern Spring Mountains. This geologic map improves on previous geologic mapping of the same area (Wahl and others, 1997) by providing new and updated Quaternary and bedrock geology, new geophysical interpretations of faults beneath the basins, and improved GIS coverages. Concurrent publications to this one include a new isostatic gravity map (Ponce and others, 1999) and a new aeromagnetic map (Ponce, 1999).

  4. The Distribution and Health Risk Assessment of Metals in Soils in the Vicinity of Industrial Sites in Dongguan, China.

    Science.gov (United States)

    Liu, Chao; Lu, Liwen; Huang, Ting; Huang, Yalin; Ding, Lei; Zhao, Weituo

    2016-08-19

    Exponential industrialization and rapid urbanization have resulted in contamination of soil by metals from anthropogenic sources in Dongguan, China. The aims of this research were to determine the concentration and distribution of various metals (arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), nickel (Ni), lead (Pb) and zinc (Zn)) in soils and identify their potential health risks for local residents. A total of 106 soil samples were collected from the vicinity of industrial sites in Dongguan. Two types of samples were collected from each site: topsoil (0-20 cm, TS) and shallow soil (20-50 cm, SS). Results showed that the soils were contaminated by metals and pollution was mainly focused on TS. The geoaccumulation index (Igeo) and pollution indexes (PI) implied that there was a slight increase in the concentrations of Cd, Cu, Hg, Ni, and Pb, but the metal pollution caused by industrial activities was less severe, and elements of As and Cr exhibited non-pollution level. The risk assessment results suggested that there was a potential health risk associated with As and Cr exposure for residents because the carcinogenic risks of As and Cr via corresponding exposure pathways exceeded the safety limit of 10(-6) (the acceptable level of carcinogenic risk for humans). Furthermore, oral ingestion and inhalation of soil particles are the main exposure pathways for As and Cr to enter the human body. This study may provide basic information of metal pollution control and human health protection in the vicinity of industrial regions.

  5. Marketing System of Fresh Friut and Vegetable: The Role of Modern and Wholesale Market in Jakarta and the Vicinity

    Directory of Open Access Journals (Sweden)

    Togar A. Napitupulu

    2010-05-01

    Full Text Available Marketing system of fresh fruits and vegetable in the context of the rapidly growing dynamic markets in Jakarta and the vicinity was studied. Unstructured interviews and observations of key persons, and panels were conducted, primarily in three main wholesale markets in Jakarta and the vicinity and some supermarkets. It was found that the availability of management services and associated facilities are not yet fully compatible with modern markets. Their role, therefore, in catering to the supermarkets is limited, in particular for vegetables due to requirements on quality and delivery schedules. In general, supermarkets procure their supply directly from production centers through special/dedicated suppliers, which currently amounts to about 1% to 5% of total production from production centers. If policy and conducive economic incentive are available, wholesale markets are not only domain of public investment anymore, but also private investments alike. The newly established wholesale markets show that they now have a higher rate of utilization than in the years before. It is therefore for the local government and the central government to furthers devise conducive policy and regulatory measures, and for the private to take this opportunity in terms of investment in developing the economy of the region. 

  6. Streamflow Changes in the Vicinity of Seismogenic Fault After the 1999 Chi-Chi Earthquake

    Science.gov (United States)

    Liu, Ching-Yi; Chia, Yeeping; Chuang, Po-Yu; Wang, Chi-Yuen; Ge, Shemin; Teng, Mao-Hua

    2017-09-01

    Changes in streamflow have been observed at 23 stream gauges in central Taiwan after the 1999 M W 7.6 Chi-Chi earthquake. Post-earthquake increases, ranging from 58 to 833% in discharge, were recorded at 22 gauges on four rivers and their tributaries. The streamflow increase typically peaked in 2-3 days and followed by a slow decay for a month or more. An increased groundwater discharge to the river after the earthquake can be attributed to rock fracturing by seismic shaking as well as pore pressure rise due to compressive strain. A large decrease in discharge was recorded immediately after the earthquake at the gauge near the earthquake epicenter. Further analysis of long-term data indicates that the post-earthquake discharge at the gauge reduced to a level smaller than that at an upstream gauge for 8 months. Such a streamflow decrease might have been caused by a discharge to the streambed due to a co-seismic decrease in pore pressure induced by crustal extension during the rupture of the thrust fault.

  7. California State Waters Map Series—Monterey Canyon and vicinity, California

    Science.gov (United States)

    Dartnell, Peter; Maier, Katherine L.; Erdey, Mercedes D.; Dieter, Bryan E.; Golden, Nadine E.; Johnson, Samuel Y.; Hartwell, Stephen R.; Cochrane, Guy R.; Ritchie, Andrew C.; Finlayson, David P.; Kvitek, Rikk G.; Sliter, Ray W.; Greene, H. Gary; Davenport, Clifton W.; Endris, Charles A.; Krigsman, Lisa M.; Dartnell, Peter; Cochran, Susan A.

    2016-06-10

    IntroductionIn 2007, the California Ocean Protection Council initiated the California Seafloor Mapping Program (CSMP), designed to create a comprehensive seafloor map of high-resolution bathymetry, marine benthic habitats, and geology within the 3-nautical-mile limit of California’s State Waters. The CSMP approach is to create highly detailed seafloor maps through collection, integration, interpretation, and visualization of swath bathymetry data, acoustic backscatter, seafloor video, seafloor photography, high-resolution seismic-reflection profiles, and bottom-sediment sampling data. The map products display seafloor morphology and character, identify potential marine benthic habitats, and illustrate both the surficial seafloor geology and shallow subsurface geology.The Monterey Canyon and Vicinity map area lies within Monterey Bay in central California. Monterey Bay is one of the largest embayments along the west coast of the United States, spanning 36 km from its northern to southern tips (in Santa Cruz and Monterey, respectively) and 20 km along its central axis. Not only does it contain one of the broadest sections of continental shelf along California’s coast, it also contains Monterey Canyon, one of the largest and deepest submarine canyons in the world. Note that the California’s State Waters limit extends farther offshore between Santa Cruz and Monterey so that it encompasses all of Monterey Bay.The coastal area within the map area is lightly populated. The community of Moss Landing (population, 204) hosts the largest commercial fishing fleet in Monterey Bay in its harbor. The map area also includes parts of the cities of Marina (population, about 20,000) and Castroville (population, about 6,500). Fertile lowlands of the Salinas River and Pajaro River valleys largely occupy the inland part of the map area, and land use is primarily agricultural.The offshore part of the map area lies completely within the Monterey Bay National Marine Sanctuary. The

  8. Early Life Conditions and Physiological Stress following the Transition to Farming in Central/Southeast Europe: Skeletal Growth Impairment and 6000 Years of Gradual Recovery.

    Science.gov (United States)

    Macintosh, Alison A; Pinhasi, Ron; Stock, Jay T

    2016-01-01

    Early life conditions play an important role in determining adult body size. In particular, childhood malnutrition and disease can elicit growth delays and affect adult body size if severe or prolonged enough. In the earliest stages of farming, skeletal growth impairment and small adult body size are often documented relative to hunter-gatherer groups, though this pattern is regionally variable. In Central/Southeast Europe, it is unclear how early life stress, growth history, and adult body size were impacted by the introduction of agriculture and ensuing long-term demographic, social, and behavioral change. The current study assesses this impact through the reconstruction and analysis of mean stature, body mass, limb proportion indices, and sexual dimorphism among 407 skeletally mature men and women from foraging and farming populations spanning the Late Mesolithic through Early Medieval periods in Central/Southeast Europe (~7100 calBC to 850 AD). Results document significantly reduced mean stature, body mass, and crural index in Neolithic agriculturalists relative both to Late Mesolithic hunter-gatherer-fishers and to later farming populations. This indication of relative growth impairment in the Neolithic, particularly among women, is supported by existing evidence of high developmental stress, intensive physical activity, and variable access to animal protein in these early agricultural populations. Among subsequent agriculturalists, temporal increases in mean stature, body mass, and crural index were more pronounced among Central European women, driving declines in the magnitude of sexual dimorphism through time. Overall, results suggest that the transition to agriculture in Central/Southeast Europe was challenging for early farming populations, but was followed by gradual amelioration across thousands of years, particularly among Central European women. This sex difference may be indicative, in part, of greater temporal variation in the social status afforded

  9. Spontaneous gradual accumulation of hexagonally-aligned nano-silica on gold nanoparticles embedded in stabilized zirconia: a pathway from catalytic to NH3-sensing performance

    Science.gov (United States)

    Plashnitsa, Vladimir V.; Elumalai, Perumal; Fujio, Yuki; Kawaguchi, Toshikazu; Miura, Norio

    2011-05-01

    The present study highlights the influence of nano-impurities on the catalytic/sensing performance of nano-structured Au sensing-electrodes (SEs) housed in a quartz reactor and operated at high temperature over a long period of time. The planar sensor, made from a nano-structured Au-SE on a polished-polycrystalline (pp) yttria-stabilized zirconia (YSZ) substrate exhibited initially negligible electromotive force (emf) response to each of the examined gases (CO, CH4, C3H8, C3H6, NOx and NH3; 400 ppm each) at 700 °C in the presence of 5 vol.% oxygen and 5 vol.% water vapor. Such a poor emf response was attributed to the excellent gas-phase oxidation/reduction ability of Au nanoparticles embedded in the YSZ substrate at high temperature. The response of the planar sensor made up of nano-structured Au-SE was monitored for about 75 days at 700 °C. As a result of this long-term monitoring, we detected the appearance of highly sensitive and selective NH3 gas-sensing properties after 45-75 days of sensor operation. Detailed observation of the morphology and composition of the as-fabricated nano-structured Au-SE after 75 days operation at 700 °C revealed the gradual accumulation of hexagonally-aligned SiO2 nano-impurities on the surface of the Au nanoparticles. The NH3 sensing mechanism of the YSZ-based sensor using the spontaneously-formed composite (nano-Au + nano-SiO2)-SE is therefore proposed to be based on a strong acid-base interaction between gaseous NH3 and SiO2 nano-impurities, followed by spillover of adsorbed NH3 towards the nano-Au/pp-YSZ interface.

  10. Amplitude reduction and phase shifts of melatonin, cortisol and other circadian rhythms after a gradual advance of sleep and light exposure in humans.

    Science.gov (United States)

    Dijk, Derk-Jan; Duffy, Jeanne F; Silva, Edward J; Shanahan, Theresa L; Boivin, Diane B; Czeisler, Charles A

    2012-01-01

    The phase and amplitude of rhythms in physiology and behavior are generated by circadian oscillators and entrained to the 24-h day by exposure to the light-dark cycle and feedback from the sleep-wake cycle. The extent to which the phase and amplitude of multiple rhythms are similarly affected during altered timing of light exposure and the sleep-wake cycle has not been fully characterized. We assessed the phase and amplitude of the rhythms of melatonin, core body temperature, cortisol, alertness, performance and sleep after a perturbation of entrainment by a gradual advance of the sleep-wake schedule (10 h in 5 days) and associated light-dark cycle in 14 healthy men. The light-dark cycle consisted either of moderate intensity 'room' light (∼90-150 lux) or moderate light supplemented with bright light (∼10,000 lux) for 5 to 8 hours following sleep. After the advance of the sleep-wake schedule in moderate light, no significant advance of the melatonin rhythm was observed whereas, after bright light supplementation the phase advance was 8.1 h (SEM 0.7 h). Individual differences in phase shifts correlated across variables. The amplitude of the melatonin rhythm assessed under constant conditions was reduced after moderate light by 54% (17-94%) and after bright light by 52% (range 12-84%), as compared to the amplitude at baseline in the presence of a sleep-wake cycle. Individual differences in amplitude reduction of the melatonin rhythm correlated with the amplitude of body temperature, cortisol and alertness. Alterations in the timing of the sleep-wake cycle and associated bright or moderate light exposure can lead to changes in phase and reduction of circadian amplitude which are consistent across multiple variables but differ between individuals. These data have implications for our understanding of circadian organization and the negative health outcomes associated with shift-work, jet-lag and exposure to artificial light.

  11. YB-1 gene expression is kept constant during myocyte differentiation through replacement of different transcription factors and then falls gradually under the control of neural activity.

    Science.gov (United States)

    Kobayashi, Shunsuke; Tanaka, Toru; Moue, Masamitsu; Ohashi, Sachiyo; Nishikawa, Taishi

    2015-11-01

    We have previously reported that translation of acetylcholine receptor α-subunit (AChR α) mRNA in skeletal muscle cells is regulated by Y-box binding protein 1 (YB-1) in response to neural activity, and that in the postnatal mouse developmental changes in the amount of YB-1 mRNA are similar to those of AChR α mRNA, which is known to be regulated by myogenic transcription factors. Here, we examined transcriptional regulation of the YB-1 gene in mouse skeletal muscle and differentiating C2C12 myocytes. Although neither YB-1 nor AChR α was detected at either the mRNA or protein level in adult hind limb muscle, YB-1 expression was transiently activated in response to denervation of the sciatic nerve and completely paralleled that of AChR α, suggesting that these genes are regulated by the same transcription factors. However, during differentiation of C2C12 cells to myotubes, the level of YB-1 remained constant even though the level of AChR α increased markedly. Reporter gene, gel mobility shift and ChIP assays revealed that in the initial stage of myocyte differentiation, transcription of the YB-1 gene was regulated by E2F1 and Sp1, and was then gradually replaced under the control of both MyoD and myogenin through an E-box sequence in the proximal region of the YB-1 gene promoter. These results suggest that transcription factors for the YB-1 gene are exchanged during skeletal muscle cell differentiation, perhaps playing a role in translational control of mRNAs by YB-1 in both myotube formation and the response of skeletal muscle tissues to neural stimulation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Long-term outcome of gradual reduction using overhead traction for developmental dysplasia of the hip over 6 months of age.

    Science.gov (United States)

    Kaneko, Hiroshi; Kitoh, Hiroshi; Mishima, Kenichi; Matsushita, Masaki; Ishiguro, Naoki

    2013-09-01

    In children over 6 months of age with developmental dysplasia of the hip (DDH), achieving a concentrically reduced hip while avoiding avascular necrosis (AVN) is challenging. The utility of gradual reduction (GR) using traction has insufficient evidence. We therefore report the long-term outcome of GR using overhead traction (OHT). We retrospectively reviewed 67 patients with DDH (75 hips) treated with GR using OHT over 6 months of age. The age at reduction ranged from 7 months to 4 years. All patients were followed up until skeletal maturity with a mean duration of 15.6 years. Pelvic radiographs were used to assess AVN, acetabular development, and the Severin classification. We determined the factors affecting the outcome at skeletal maturity. Seventy-two hips (96%) were successfully reduced, 2 required subsequent closed reduction and 1 underwent open reduction. AVN occurred in 2 hips (2.7%). Among 48 hips (64%) with residual acetabular dysplasia, 31 were treated with Salter innominate osteotomy (SIO) between 5 and 6 years of age. Finally, 62 hips (82.7%) showed satisfactory outcome (56 in Severin class I and 6 in class II), whereas 13 showed unsatisfactory outcome (class III). Although we found no significant factors affecting the outcome, most of the hips treated with SIO were included in the satisfactory group. GR using OHT could effectively minimize the risk of developing AVN in patients with DDH over 6 months of age at presentation. SIO at preschool age may play a beneficial role in the long-term outcome of GR using OHT.

  13. Elevated NH 3 and NO 2 air concentrations and nitrogen deposition rates in the vicinity of a highway in Southern Bavaria

    Science.gov (United States)

    Kirchner, Manfred; Jakobi, Gert; Feicht, Ernst; Bernhardt, Markus; Fischer, Anton

    A transect study consisting of air concentration and deposition measurements of nitrogen compounds was performed to estimate the potential influence of car emissions on the nitrogen input to ecosystems. Therefore, two transects each consisting of 4 plots, the first in a coniferous forest and the second one in an extensively farmed grassland, were installed perpendicular to a highway south of Munich (Bavaria). Both profiles were influenced mainly by car emissions and showed only small local influences caused by agricultural activities. In the framework of a pilot study based upon denuder measurements we found a strong temporal dependency of both nitrogen dioxide (NO 2) and ammonia (NH 3) concentrations on traffic density. In the main study air concentrations of NO 2 and NH 3 were measured by passive samplers; they used as the basis for the estimation of dry deposition. These estimations have been compared with the results of analyses from simultaneously conducted canopy throughfall deposition and open air bulk measurements of nitrate (NO 3-) and ammonium (NH 4+). Additionally, within the forest transect the variety of different soil vegetation species was recorded and quantified. We obtained a strong gradient of gas concentrations along both profiles. Whereas the bulk deposition remained quite constant along the non-forested transect, the nitrogen throughfall deposition rate diminished substantially with the distance from the highway. The deposition rate at the forest edge was twice of that inside. The nitrogen load estimated for the examined forest in the vicinity of the highway was comparable to other forest ecosystems situated near diffuse emission sources from agriculture. It could be shown that changes in soil composition and soil vegetation along the forest transect are caused by decreasing nitrogen deposition with distance from the highway. The application of road salt in winter leads to further impacts.

  14. Rosa damascena decreased mortality in adult Drosophila.

    Science.gov (United States)

    Jafari, Mahtab; Zarban, Asghar; Pham, Steven; Wang, Thomas

    2008-03-01

    The effects of a rose-flower extract, Rosa damascena, on the mortality rate of Drosophila melanogaster was evaluated in this study. R. damascena is a potent antioxidant that has many therapeutic uses in addition to its perfuming effects. Supplementing Drosophila with this rose extract resulted in a statistically significant decrease in mortality rate in male and female flies. Moreover, the observed anti-aging effects were not associated with common confounds of anti-aging properties, such as a decrease in fecundity or metabolic rate.

  15. The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major modifications of the viral genome.

    Science.gov (United States)

    Krug, Peter W; Holinka, Lauren G; O'Donnell, Vivian; Reese, Bo; Sanford, Brenton; Fernandez-Sainz, Ignacio; Gladue, Douglas P; Arzt, Jonathan; Rodriguez, Luis; Risatti, Guillermo R; Borca, Manuel V

    2015-02-01

    African swine fever virus (ASFV) causes a contagious and often lethal disease of feral and domestic swine. Experimental vaccines derived from naturally occurring, genetically modified, or cell culture-adapted ASFV have been evaluated, but no commercial vaccine is available to control African swine fever (ASF). We report here the genotypic and phenotypic analysis of viruses obtained at different passages during the process of adaptation of a virulent ASFV field isolate from the Republic of Georgia (ASFV-G) to grow in cultured cell lines. ASFV-G was successively passaged 110 times in Vero cells. Viruses obtained at passages 30, 60, 80, and 110 were evaluated in vitro for the ability to replicate in Vero cells and primary swine macrophages cultures and in vivo for assessing virulence in swine. Replication of ASFV-G in Vero cells increased with successive passages, corresponding to a decreased replication in primary swine macrophages cultures. In vivo, progressive loss of virus virulence was observed with increased passages in Vero cells, and complete attenuation of ASFV-G was observed at passage 110. Infection of swine with the fully attenuated virus did not confer protection against challenge with virulent parental ASFV-G. Full-length sequence analysis of each of these viruses revealed significant deletions that gradually accumulated in specific areas at the right and left variable ends of the genome. Mutations that result in amino acid substitutions and frameshift mutations were also observed, though in a rather limited number of genes. The potential importance of these genetic changes in virus adaptation/attenuation is discussed. The main problem in controlling ASF is the lack of vaccines. Attempts to produce vaccines by adaptation of ASFV to cultured cell lines have been made. These attempts led to the production of attenuated viruses that conferred only homologous protection. Specifics regarding adaptation of these isolates to cell cultures have been

  16. Elevated plasma homocysteine in association with decreased ...

    African Journals Online (AJOL)

    Conclusion: This study showed a significant increase in plasma tHcy coexisting with a decrease in plasma vitamin B12 TC, LDLC and HDLC, in depressed patients. Increased plasma homocysteine could be a sensitive indicator of plasma B vitamin deficiency. Keywords: Cholesterol; Depression; Homocysteine; Tryptophan; ...

  17. Aggregate Unemployment Decreases Individual Returns to Education

    Science.gov (United States)

    Ammermueller, Andreas; Kuckulenz, Anja; Zwick, Thomas

    2009-01-01

    Aggregate unemployment may affect individual returns to education through qualification-specific responses in participation and wage bargaining. This paper shows that an increase in regional unemployment by 1% decreases returns to education by 0.005 percentage points. This implies that higher skilled employees are better sheltered from labour…

  18. Decreasing Smoking Behavior through Subliminal Stimulation Treatments.

    Science.gov (United States)

    Glover, Elbert D.

    1979-01-01

    Determines whether subliminal perception can be used as a means for altering cigarette smoking behavior. Smoking behavior was not altered through subliminal perception as carried out in this study. There was evidence that smoking behavior was altered, but it was an unpredicted change. Some subjects decreased smoking patterns. (Author)

  19. Autoimmune Response Confers Decreased Cardiac Function in ...

    African Journals Online (AJOL)

    Purpose: To explore the effect of autoimmune response on the decreased cardiac function in patients with rheumatic mitral lesion following valve replacement. Methods: In this case-controlled study, 29 patients who had undergone valve replacement as a result of mitral lesion were enrolled (mean age = 48.7 years). Twenty ...

  20. Elevated plasma homocysteine in association with decreased ...

    African Journals Online (AJOL)

    monoamine neurotransmitters and depression of mood.7 A. Elevated plasma homocysteine in association with decreased vitamin. B12, folate, serotonin, lipids and lipoproteins in depressed patients. MO Ebesunun1, HU Eruvulobi1, T Olagunju1, OA Owoeye2. 1Chemical Pathology, Obafemi Awolowo College of Health ...

  1. Decreasing prevalence of social drinkers in Australia.

    Science.gov (United States)

    Callinan, Sarah; Pennay, Amy; Livingston, Michael

    2017-04-01

    There has been a recent decrease in population level alcohol consumption in Australia, particularly in young people. Whether this is due to increasing abstinence or a shift in the way people think about alcohol is not known. The aim of this study is to investigate trends in self-identification of drinker types in Australia from 2001 to 2013 in light of shifting patterns of alcohol consumption in Australia. Five waves of the National Drug Strategy Household Survey from 2001 to 2013 (N=118,416) were used to assess trends in self-identification as a drinker type (non-, ex-, occasional, light, social, heavy and binge drinker). Consumption patterns and demographics of the self-identified groups were also examined. The pattern of self-identification has mostly remained steady over time. The two exceptions to this are a decrease in identification as a social drinker (28% to 22%) and a corresponding increase in identification as a non-drinker (from 19% to 27%). There are few changes over time in the demographic make-up of, or consumption patterns in, the social drinker category with the exception of those over 50, who continue to identify as social drinkers at the same rate. The recent increase in abstinence in Australia seems to be matched by a corresponding decrease in self-identified social drinkers, particularly among those under 50. This indicates that the decrease in consumption is not occurring in those most likely to experience harms. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Preavoidance hypercapnia and decreased hematocrit in micropigs.

    Science.gov (United States)

    Anderson, D E; Fedorova, O V; French, A W

    1996-01-01

    Previous studies found that regular confinement of dogs in an experimental environment preceding onset of an avoidance task was associated with increases in blood pressure and decreases in heart rate and respiration rate that were not prevented by adrenergic antagonists. The present study investigated a) whether divergent changes in blood pressure and heart rate also occur in micropigs preceding onset of an avoidance task, and b) the nature of changes in blood gases, plasma pH, plasma bicarbonate, hematocrit, and plasma electrolytes observed under these conditions. Blood pressure increased and heart rate decreased during 2-h preavoidance periods, whereas both blood pressure and heart rate were elevated during 20-min avoidance periods. During preavoidance periods, pO2, plasma pH, and plasma potassium pCO2 were decreased below home kennel levels during early preavoidance, whereas pCO2 and plasma bicarbonate were persistently increased and hematocrit was persistently decreased for the duration of the preavoidance periods. Each of these changes was reversed during the avoidance sessions. These findings suggest that behaviorally induced hypercapnia might participate in blood pressure regulation via increased renal sodium/hydrogen exchange and renal sodium retention.

  3. Changes in peak flow with decreased forestry practices: analysis using watershed runoff data.

    Science.gov (United States)

    Komatsu, Hikaru; Shinohara, Yoshinori; Kume, Tomonori; Otsuki, Kyoichi

    2011-06-01

    The prevalence of forestry practices such as thinning and pruning have gradually decreased since the 1980s. Researchers have noted an increased flood risk with decreased forestry practices for coniferous plantations in Japan on the basis of infiltration and overland flow measurements at a plot scale (typically several square meters). However, no studies have examined changes in peak flow with decreased forestry practices at a watershed scale (typically several tens or hundreds of square kilometers) even though flood disasters generally occur at this scale in Japan. We examined changes in frequency distributions of daily precipitation (P) and runoff (Q) during the period 1979-2007 at the Terauchi watershed, where forestry practices are known to have decreased. For this purpose, we divided P and Q data into 14 and 15 classes according to the magnitude, respectively, and examined changes in the frequency for each class during the period. We observed no significant increasing trend for any P or Q class. Even when taking into account the effect of interannual variations in precipitation on the frequency for each Q class, there was no significant increasing trend in the frequencies except for two Q classes with moderate Q values. These results suggest that the increase in flood risk due to decreased forestry practices might be less than expected. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Lift Force Acting on Body in Liquid in the Vicinity of Boundary Executing Tangential Oscillations

    Science.gov (United States)

    Ivanova, A. A.; Kozlov, V. G.

    2014-10-01

    The average force acting on a cylindrical or spherical body placed near the boundary of cylindrical cavity filled with liquid and executing rotational vibrations is experimentally studied. The repulsive lift force acting on solid is found and measured using the method of body suspension in the gravity field. In horizontal cavity the repulsive force provides steady state of light cylinder near the upper boundary at a distance comparable with the thickness of the Stokes layer. The heavy sphere which hangs on thread repulses from the wall of vertical cylindrical cavity under torsional vibration. The dependence of the average lift force on the amplitude and frequency of vibrations and on distance between the body and the boundary has been investigated. Results are presented on the plane of dimensionless parameters. In the examined frequency range the lift force acting on cylinder decreases exponentially with distance from the boundary. Lift force acting on sphere decreases with distance and strongly depends on dimensionless frequency of vibration. Conclusion that lift force is generated by body oscillations excited by its viscous interaction with the oscillating boundary is done. The found phenomenon is important for control of inclusions under microgravity conditions.

  5. Visual accommodation and target detection in the vicinity of a window post.

    Science.gov (United States)

    Chong, J; Triggs, T J

    1989-02-01

    The visual environment of a driver in a car or a pilot in an airplane has intervening objects from the vehicle such as A-pillar posts between the windscreen and the doors in the car or cockpit pillars in the airplane. The presence of such objects can bias the observer's visual accommodation response because of the Mandelbaum effect (e.g., Owens, 1979). When subjects were allowed to focus toward a distance by looking through a large aperture in an intervening post, the detection (monocular) of a briefly presented distant target was found to be significantly better than when no aperture was present. When the size of the aperture was decreased from 2.3 to 1.15 deg diameter, target detection performance was significantly decreased and remained constant as further reduction of foveal cues was made. Although the detection results were generally in agreement with the visual accommodation results, detection accuracy changed significantly only with marked changes in accommodation. In addition to an accommodation bias, interference to target detection was also observed for those targets occurring at a laterally proximal position to the intervening object.

  6. Kinetic study of CO oxidation on step decorated Pt(1 1 1) vicinal single crystal electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Chen Qingsong [Institute of Electrochemistry, University of Alicante, Apartado 99, E-03080 Alicante (Spain); State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005 (China); Feliu, Juan M., E-mail: juan.feliu@ua.es [Institute of Electrochemistry, University of Alicante, Apartado 99, E-03080 Alicante (Spain); Berna, Antonio; Climent, Victor [Institute of Electrochemistry, University of Alicante, Apartado 99, E-03080 Alicante (Spain); Sun Shigang, E-mail: sgsun@xmu.edu.cn [State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005 (China)

    2011-07-01

    Highlights: > Chronoamperometry has been used to study CO oxidation on Pt stepped surfaces. > Adatoms step decoration allows determination of the role of steps on CO oxidation. > Rate constant decreases after step decoration with adatoms. > Tafel slopes are around 60-90 mV/dec, suggesting a Langmuir-Hinshelwood mechanism. - Abstract: In this work, surface modification at atomic level was applied to study the reactivity of step sites on platinum single crystal surfaces. Stepped platinum single crystal electrodes with (1 1 1) terraces separated by monoatomic step sites with different symmetry were decorated with irreversibly adsorbed adatoms, without blocking the terrace sites, and characterized in 0.1 M HClO{sub 4} solution. The kinetics of CO oxidation on the different platinum single crystal planes as well as on the step decorated surfaces has been studied using chronoamperometry. The apparent rate constants, which were determined by fitting the experimental data to a mean-field model, decrease after the steps of platinum single crystal electrodes have been blocked by the adatoms. This behavior indicates that steps are active sites for CO oxidation. Tafel slopes measured from the potential dependence of the apparent rate constants of CO oxidation were similar in all cases. This result demonstrates that the electrochemical oxidation of the CO adlayer on all the surfaces follows the same Langmuir-Hinshelwood model, irrespectively of step modification.

  7. Amplitude reduction and phase shifts of melatonin, cortisol and other circadian rhythms after a gradual advance of sleep and light exposure in humans.

    Directory of Open Access Journals (Sweden)

    Derk-Jan Dijk

    Full Text Available BACKGROUND: The phase and amplitude of rhythms in physiology and behavior are generated by circadian oscillators and entrained to the 24-h day by exposure to the light-dark cycle and feedback from the sleep-wake cycle. The extent to which the phase and amplitude of multiple rhythms are similarly affected during altered timing of light exposure and the sleep-wake cycle has not been fully characterized. METHODOLOGY/PRINCIPAL FINDINGS: We assessed the phase and amplitude of the rhythms of melatonin, core body temperature, cortisol, alertness, performance and sleep after a perturbation of entrainment by a gradual advance of the sleep-wake schedule (10 h in 5 days and associated light-dark cycle in 14 healthy men. The light-dark cycle consisted either of moderate intensity 'room' light (∼90-150 lux or moderate light supplemented with bright light (∼10,000 lux for 5 to 8 hours following sleep. After the advance of the sleep-wake schedule in moderate light, no significant advance of the melatonin rhythm was observed whereas, after bright light supplementation the phase advance was 8.1 h (SEM 0.7 h. Individual differences in phase shifts correlated across variables. The amplitude of the melatonin rhythm assessed under constant conditions was reduced after moderate light by 54% (17-94% and after bright light by 52% (range 12-84%, as compared to the amplitude at baseline in the presence of a sleep-wake cycle. Individual differences in amplitude reduction of the melatonin rhythm correlated with the amplitude of body temperature, cortisol and alertness. CONCLUSIONS/SIGNIFICANCE: Alterations in the timing of the sleep-wake cycle and associated bright or moderate light exposure can lead to changes in phase and reduction of circadian amplitude which are consistent across multiple variables but differ between individuals. These data have implications for our understanding of circadian organization and the negative health outcomes associated with shift

  8. A cam deformity is gradually acquired during skeletal maturation in adolescent and young male soccer players: a prospective study with minimum 2-year follow-up.

    Science.gov (United States)

    Agricola, Rintje; Heijboer, Marinus P; Ginai, Abida Z; Roels, Pauline; Zadpoor, Amir A; Verhaar, Jan A N; Weinans, Harrie; Waarsing, Jan H

    2014-04-01

    could also significantly predict the formation of cam deformities (α angle >60°) at follow-up. In youth soccer players, cam deformities gradually develop during skeletal maturation and are probably stable from the time of growth plate closure. The formation of a cam deformity might be prevented by adjusting athletic activities during a small period of skeletal growth, which will have a major effect on the prevalence of hip osteoarthritis.

  9. Flowing equation gradually varied in rectangles channels on depth curve; Ecuacion del flujo gradualmente variado en canales rectangulares de fondo curvo

    Energy Technology Data Exchange (ETDEWEB)

    Sotelo-Avila, G.; Gallegos-Silva, J. [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)

    2002-03-01

    The study of channel flow usually have its basis in the hydrostatic distribution of pressure and the rectilinear flow hypotheses. It is from this hypothesis that the main flow equations are obtained. However, this is not applicable to a vertically curved flow that is present in a curved bed channel. This kind of channel is used to join two different slopes or in ski jumps. This kind of flow presents several changes from the rectilinear flow as in the velocity and pressure distributions and even in the energy loses. The authors of this article propose an equation of gradually varied flow for vertically-curved bed rectangular channels that adds a coefficient to modify the velocity in the calculus of the local friction gradient. With these results is possible now to analyze flow profiles in vertically-curved bed channels where before were used the methods for straight channels and therefore, increase accuracy. [Spanish] Las hipotesis del movimiento rectilineo y de distribucion hidrostatica de la presion son ciertamente las mas importantes en la hidraulica de canales, y de ellas se derivan los principales modelos de flujo que usualmente emplean. Sin embargo, no es valido aplicar la misma hipotesis y metodos de analisis al flujo curvilineo, que ocurre cuando el canal adopta curvaturas verticales en el fondo, las cuales inducen cambios importantes en la distribucion de la velocidad, presion y hasta en la perdida d energia. Tal es el caso de canales que contienen curvas verticales para unir tramos de distintas pendientes y producir el cambio en la direccion del flujo en cubetas deflectoras y vertedores en tunel. Los autores de este articulo proponen una ecuacion de flujo gradualmente variado en canales rectangulares de fondo curvo, esta es de gran utilidad en la determinacion del perfil del flujo con dichas caracteristicas, donde se plantea la adicion de un factor de amplificacion de la velocidad en el calculo del gradiente local de friccion, para tomar en cuenta el

  10. Atitude empreendedora: validação de um instrumento de medida com base no modelo de resposta gradual da teoria da resposta ao item.

    Directory of Open Access Journals (Sweden)

    Antônio Cezar Bornia

    2013-10-01

    Full Text Available A escala instrumento de medida de atitude empreendedora (Imae, desenvolvida por Souza e Lopes Jr. (2005, contém duas dimensões: prospecção e inovação, e gestão e persistência. Com a finalidade de verificar a validade e o intervalo em que propicia a medida de atitude empreendedora, além de investigar sua capacidade de discriminar a resposta que o indivíduo está apto a dar, o objetivo deste artigo é validar a escala Imae por meio do modelo de resposta gradual da teoria da resposta ao item (TRI, que revolucionou a teoria de medidas. A TRI, construtos da psicologia utilizados em estudos de discriminação de respostas, em especial em grandes amostras de respondentes a um determinado fenômeno, é constituída de modelos matemáticos que relacionam um ou mais traços latentes (não observados de um indivíduo com a probabilidade de este dar uma determinada resposta a um item. O ponto crucial da TRI é que ela leva em consideração o item particularmente, sem relevar os escores totais, portanto as conclusões não dependem apenas do teste ou questionário, mas de cada elemento que o compõe. Os principais resultados encontrados foram a identificação de dois níveis da escala, denominados âncoras, que permitem interpretar tendências de pessoas com atitude empreendedora e a constatação de que os itens da escala Imae apresentam boa capacidade de discriminar a resposta que o indivíduo está apto a dar, o que confere qualidade aos itens e, portanto, à escala. A importância deste estudo reside no papel fundamental que a atitude desempenha nas escolhas que as pessoas fazem em relação à própria vida, de modo a ajudá-las a determinar seus próprios atos.

  11. Construction Noise Decreases Reproductive Efficiency in Mice

    Science.gov (United States)

    Rasmussen, Skye; Glickman, Gary; Norinsky, Rada; Quimby, Fred W; Tolwani, Ravi J

    2009-01-01

    Excessive noise is well known to impair rodent health. To better understand the effect of construction noise and to establish effective noise limits during a planned expansion of our vivarium, we analyzed the effects of construction noise on mouse gestation and neonatal growth. Our hypothesis was that high levels of construction noise would reduce the number of live births and retard neonatal growth. Female Swiss Webster mice were individually implanted with 15 B6CBAF1/J embryos and then exposed to 70- and 90-dBA concrete saw cutting noise samples at defined time points during gestation. In addition, groups of mice with litters were exposed to noise at 70, 80, or 90 dBA for 1 h daily during the first week after parturition. Litter size, birth weight, incidence of stillborn pups, and rate of neonatal weight gain were analyzed. Noise decreased reproductive efficiency by decreasing live birth rates and increasing the number of stillborn pups. PMID:19653943

  12. Hemodilution causes decreased compliance in puppies.

    Science.gov (United States)

    Mavroudis, C; Ebert, P A

    1978-09-01

    Cardiopulmonary bypass and hemodilution in the newborn have been associated with increased myocardial edema, which may be due to immature connective tissue formation. Five adult and four puppy dogs were placed on bypass while compliance and ventricular function (intraventricular balloon) were measured during normohemoconcentration (NH) (hematocrit 45.1, osmolality 307) and hemodilution with normal saline (hematocrit 24.7, osmolality 307). Compared with NH, the adult group showed no change in compliance or function after 90 min of hemodilution. The puppy group showed a marked decrease in compliance with hemodilution compared to NH (P sensitive to edema formation than the adult during hemodilution and that filling pressures do not necessarily reflect ventricular performance during the early post-perfusion period when compliance is decreased.

  13. The decreasing cost of telemedicine and telehealth.

    Science.gov (United States)

    Doolittle, Gary C; Spaulding, Ashley O'Neal; Williams, Arthur R

    2011-11-01

    The teleoncology practice based at the University of Kansas Medical Center (KUMC) in Kansas City, Kansas, is one of the longest running practices of its kind worldwide. The practice began in 1995 and connected an oncologist at KUMC with a rural medical center in Hays, Kansas. Fifteen years later, the practice continues to thrive at Hays Medical Center and has also expanded to include two additional sites within the state-the Northeast Kansas Center for Health and Wellness in Horton and Goodland Regional Medical Center in Goodland-that offer regularly scheduled teleoncology clinics. While the KUMC practice has witnessed an expansion in service sites throughout its history, the practice has seen a significant decrease in the costs associated with providing such services since its inception. The cost decrease can, in part, be attributed to an increase in the number of teleoncology visits conducted through the practice since it began. In Fiscal Year 1995 (FY 1995), 103 teleoncology visits resulted in a cost per visit of $812. Five years later, the FY 2000 $410 per visit cost for 121 visits was almost half the cost identified in the initial cost analysis. The FY 2003 cost per visit for 219 visits saw another decrease to $401, and the most recent FY 2005 cost analysis yielded another decrease to $251 per visit for 235 visits. The data reported below are likely to be the best now available to track time trends in the cost of providing telemedicine or telehealth consultations. The Conclusion and Policy Recommendations at the end of this article will focus on both the cost-time profile and some other challenges and lessons learned.

  14. Decreased Fecundity and Sperm DNA Methylation Patterns

    Science.gov (United States)

    Jenkins, Timothy G.; Aston, Kenneth I.; Meyer, Tyson D.; Hotaling, James M.; Shamsi, Monis B.; Johnstone, Erica B.; Cox, Kyley J.; Stanford, Joseph B.; Porucznik, Christina A.; Carrell, Douglas T.

    2016-01-01

    Objective To evaluate the relationship between epigenetic patterns in sperm and fecundity. Design Prospective study of couples trying to conceive, utilizing semen samples collected through the HOPE study, at the University of Utah. Setting Academic Andrology and IVF Laboratory Patients DNA methylation alterations associated with fecundity were analyzed in 124 semen samples. 27 semen samples from couples who conceived within 2 months of attempting a pregnancy and a total of 29 semen samples from couples who were unable to achieve a pregnancy within 12 months were analyzed to identify regions of interest. Interventions None. Main Outcome Measures Genome-wide assessment of differential sperm DNA methylation and standard semen analysis. Results No differences in sperm count, sperm morphology, or semen volume were observed between the patients achieving a pregnancy within 2 months of study time and those not obtaining a pregnancy within 12 months. However, using data from the Human Methylation 450k array analysis we did identify 2 genomic regions with significantly decreased (FDR <0.01) methylation and 3 genomic regions with significantly increased methylation in the “failure-to-conceive” group. Interestingly, the only two sites where decreased methylation was associated with reduced fecundity are at closely related genes known to be expressed in sperm, HSPA1L and HSPA1B. Conclusions Our data suggest that there are genomic loci where DNA methylation alterations are associated with decreased fecundity. We have thus identified candidate loci for future study to verify these results and investigate the causative or contributory relationship between altered sperm methylation and decreased fecundity. PMID:26453269

  15. Accumulation of Aluminium and Physiological Status of Tree Foliage in the Vicinity of a Large Aluminium Smelter

    Science.gov (United States)

    Wannaz, E. D.; Rodriguez, J. H.; Wolfsberger, T.; Carreras, H. A.; Pignata, M. L.; Fangmeier, A.; Franzaring, J.

    2012-01-01

    A pollution gradient was observed in tree foliage sampled in the vicinity of a large aluminium production facility in Patagonia (Argentina). Leaves of Eucalyptus rostrata, and Populus hybridus and different needle ages of Pinus spec. were collected and concentrations of aluminium (Al) and sulphur (S) as well as physiological parameters (chlorophyll and lipid oxidation products) were analyzed. Al and S concentrations indicate a steep pollution gradient in the study showing a relationship with the physiological parameters in particular membrane lipid oxidation products. The present study confirms that aluminium smelting results in high Al and sulphur deposition in the study area, and therefore further studies should be carried out taking into account potentially adverse effects of these compounds on human and ecosystem health. PMID:22654642

  16. Statistical analysis of electromagnetic radiation measurements in the vicinity of GSM/UMTS base station antenna masts.

    Science.gov (United States)

    Koprivica, Mladen; Neskovic, Natasa; Neskovic, Aleksandar; Paunovic, George

    2014-01-01

    As a result of dense installations of public mobile base station, additional electromagnetic radiation occurs in the living environment. In order to determine the level of radio-frequency radiation generated by base stations, extensive electromagnetic field strength measurements were carried out for 664 base station locations. Base station locations were classified into three categories: indoor, masts and locations with installations on buildings. Having in mind the large percentage (47 %) of sites with antenna masts, a detailed analysis of this location category was performed, and the measurement results were presented. It was concluded that the total electric field strength in the vicinity of base station antenna masts in no case exceeded 10 V m(-1), which is quite below the International Commission on Non-Ionizing Radiation Protection reference levels. At horizontal distances >50 m from the mast bottom, the median and maximum values were <1 and 2 V m(-1), respectively.

  17. Production of neutron-rich nuclides in the vicinity of N = 126 shell closure in multinucleon transfer reactions

    Directory of Open Access Journals (Sweden)

    Karpov Alexander

    2017-01-01

    Full Text Available Multinucleon transfer in low-energy nucleus-nucleus collisions is widely discussed as a method of production of yet-unknown neutron-rich nuclei hardly accessible (or inaccessible by other methods. Modeling of complicated dynamics of nuclear reactions induced by heavy ions is done within a multidimensional dynamical model of nucleus-nucleus collisions based on the Langevin equations. The model gives a continuous description of the system evolution starting from the well-separated target and projectile in the entrance channel of the reaction up to the formation of final reaction products. In this paper, rather recent sets of experimental data for the 136Xe+198Pt,208Pb reactions are analyzed together with the production cross sections for neutron-rich nuclei in the vicinity of the N = 126 magic shell.

  18. Temperature Changes in the Vicinity of Thermally Loaded Structure Embedded in the Soil: Effect of Sand Content and Saturation Degree

    Science.gov (United States)

    Różański, Adrian

    2017-06-01

    Due to the rapid development of geothermal technologies, the problem of efficient and proper evaluation of soil thermal conductivity becomes extremely important. Factors mostly affecting the soil conductivity are the conductivity of solid phase and the degree of saturation. The former one is mainly affected by the mineral composition, in particular, by the content of quartz whose conductivity is the highest one among all the minerals forming soil skeleton. Organic matter, because of its relatively low conductivity, influences the solid conductivity as well. The problem addressed in the paper is the influence of mentioned factors on temperature changes in the vicinity of thermally loaded structure embedded in the soil medium. Numerical simulations are carried out for different values of soil thermal conductivity resulting from various quartz contents and degrees of saturation. In addition, a weak coupled - heat and water transport - problem is considered.

  19. Anomalous metallic state in the vicinity of metal to valence-bond solid insulator transition in LiVS2.

    Science.gov (United States)

    Katayama, N; Uchida, M; Hashizume, D; Niitaka, S; Matsuno, J; Matsumura, D; Nishihata, Y; Mizuki, J; Takeshita, N; Gauzzi, A; Nohara, M; Takagi, H

    2009-10-02

    We investigate LiVS2 and LiVSe2 with a triangular lattice as itinerant analogues of LiVO2 known for the formation of a valence-bond solid (VBS) state out of an S=1 frustrated magnet. LiVS2, which is located at the border between a metal and a correlated insulator, shows a first order transition from a paramagnetic metal to a VBS insulator at Tc approximately 305 K upon cooling. The presence of a VBS state in the close vicinity of insulator-metal transition may suggest the importance of itinerancy in the formation of a VBS state. We argue that the high temperature metallic phase of LiVS2 has a pseudogap, likely originating from the VBS fluctuation. LiVSe2 was found to be a paramagnetic metal down to 2 K.

  20. Influence of the Near Molecular Vicinity on the Temperature Regulated Fluorescence Response of Poly(N-vinylcaprolactam

    Directory of Open Access Journals (Sweden)

    Anne Enzenberg

    2016-03-01

    Full Text Available A series of new fluorescent dye bearing monomers, including glycomonomers, based on maleamide and maleic esteramide was synthesized. The dye monomers were incorporated by radical copolymerization into thermo-responsive poly(N‑vinyl-caprolactam that displays a lower critical solution temperature (LCST in aqueous solution. The effects of the local molecular environment on the polymers’ luminescence, in particular on the fluorescence intensity and the extent of solvatochromism, were investigated below as well as above the phase transition. By attaching substituents of varying size and polarity in the close vicinity of the fluorophore, and by varying the spacer groups connecting the dyes to the polymer backbone, we explored the underlying structure–property relationships, in order to establish rules for successful sensor designs, e.g., for molecular thermometers. Most importantly, spacer groups of sufficient length separating the fluorophore from the polymer backbone proved to be crucial for obtaining pronounced temperature regulated fluorescence responses.