WorldWideScience

Sample records for viable commercial applications

  1. Rapid assessment of viable but non-culturable Bacillus coagulans MTCC 5856 in commercial formulations using Flow cytometry

    Science.gov (United States)

    Majeed, Muhammed; Majeed, Shaheen; Nagabhushanam, Kalyanam; Punnapuzha, Ardra; Philip, Sheena

    2018-01-01

    Accurate enumeration of bacterial count in probiotic formulation is imperative to ensure that the product adheres to regulatory standards and citation in consumer product label. Standard methods like plate count, can enumerate only replicating bacterial population under selected culture conditions. Viable but non culturable bacteria (VBNC) retain characteristics of living cells and can regain cultivability by a process known as resuscitation. This is a protective mechanism adapted by bacteria to evade stressful environmental conditions. B. coagulans MTCC 5856(LactoSpore®) is a probiotic endospore which can survive for decades in hostile environments without dividing. In the present study, we explored the use of flow cytometry to enumerate the viable count of B. coagulans MTCC 5856 under acidic and alkaline conditions, high temperature and in commercial formulations like compressed tablets and capsules. Flow cytometry (FCM) was comparable to plate count method when the spores were counted at physiological conditions. We show that VBNC state is induced in B. coagulans MTCC 5856by high temperature and acidic pH. The cells get resuscitated under physiological conditions and FCM was sensitive to detect the VBNC spores. Flow cytometry showed excellent ability to assess the viable spore count in commercial probiotic formulations of B. coagulans MTCC 5856. The results establish Flow cytometry as a reliable method to count viable bacteria in commercial probiotic preparations. Sporulation as well as existence as VBNC could contribute to the extreme stability of B. coagulans MTCC 5856. PMID:29474436

  2. Rapid assessment of viable but non-culturable Bacillus coagulans MTCC 5856 in commercial formulations using Flow cytometry.

    Directory of Open Access Journals (Sweden)

    Muhammed Majeed

    Full Text Available Accurate enumeration of bacterial count in probiotic formulation is imperative to ensure that the product adheres to regulatory standards and citation in consumer product label. Standard methods like plate count, can enumerate only replicating bacterial population under selected culture conditions. Viable but non culturable bacteria (VBNC retain characteristics of living cells and can regain cultivability by a process known as resuscitation. This is a protective mechanism adapted by bacteria to evade stressful environmental conditions. B. coagulans MTCC 5856(LactoSpore® is a probiotic endospore which can survive for decades in hostile environments without dividing. In the present study, we explored the use of flow cytometry to enumerate the viable count of B. coagulans MTCC 5856 under acidic and alkaline conditions, high temperature and in commercial formulations like compressed tablets and capsules. Flow cytometry (FCM was comparable to plate count method when the spores were counted at physiological conditions. We show that VBNC state is induced in B. coagulans MTCC 5856by high temperature and acidic pH. The cells get resuscitated under physiological conditions and FCM was sensitive to detect the VBNC spores. Flow cytometry showed excellent ability to assess the viable spore count in commercial probiotic formulations of B. coagulans MTCC 5856. The results establish Flow cytometry as a reliable method to count viable bacteria in commercial probiotic preparations. Sporulation as well as existence as VBNC could contribute to the extreme stability of B. coagulans MTCC 5856.

  3. Rapid assessment of viable but non-culturable Bacillus coagulans MTCC 5856 in commercial formulations using Flow cytometry.

    Science.gov (United States)

    Majeed, Muhammed; Majeed, Shaheen; Nagabhushanam, Kalyanam; Punnapuzha, Ardra; Philip, Sheena; Mundkur, Lakshmi

    2018-01-01

    Accurate enumeration of bacterial count in probiotic formulation is imperative to ensure that the product adheres to regulatory standards and citation in consumer product label. Standard methods like plate count, can enumerate only replicating bacterial population under selected culture conditions. Viable but non culturable bacteria (VBNC) retain characteristics of living cells and can regain cultivability by a process known as resuscitation. This is a protective mechanism adapted by bacteria to evade stressful environmental conditions. B. coagulans MTCC 5856(LactoSpore®) is a probiotic endospore which can survive for decades in hostile environments without dividing. In the present study, we explored the use of flow cytometry to enumerate the viable count of B. coagulans MTCC 5856 under acidic and alkaline conditions, high temperature and in commercial formulations like compressed tablets and capsules. Flow cytometry (FCM) was comparable to plate count method when the spores were counted at physiological conditions. We show that VBNC state is induced in B. coagulans MTCC 5856by high temperature and acidic pH. The cells get resuscitated under physiological conditions and FCM was sensitive to detect the VBNC spores. Flow cytometry showed excellent ability to assess the viable spore count in commercial probiotic formulations of B. coagulans MTCC 5856. The results establish Flow cytometry as a reliable method to count viable bacteria in commercial probiotic preparations. Sporulation as well as existence as VBNC could contribute to the extreme stability of B. coagulans MTCC 5856.

  4. Physiology limits commercially viable photoautotrophic production of microalgal biofuels.

    Science.gov (United States)

    Kenny, Philip; Flynn, Kevin J

    2017-01-01

    Algal biofuels have been offered as an alternative to fossil fuels, based on claims that microalgae can provide a highly productive source of compounds as feedstocks for sustainable transport fuels. Life cycle analyses identify algal productivity as a critical factor affecting commercial and environmental viability. Here, we use mechanistic modelling of the biological processes driving microalgal growth to explore optimal production scenarios in an industrial setting, enabling us to quantify limits to algal biofuels potential. We demonstrate how physiological and operational trade-offs combine to restrict the potential for solar-powered algal-biodiesel production in open ponds to a ceiling of ca. 8000 L ha -1 year -1 . For industrial-scale operations, practical considerations limit production to ca. 6000 L ha -1 year -1 . According to published economic models and life cycle analyses, such production rates cannot support long-term viable commercialisation of solar-powered cultivation of natural microalgae strains exclusively as feedstock for biofuels. The commercial viability of microalgal biofuels depends critically upon limitations in microalgal physiology (primarily in rates of C-fixation); we discuss the scope for addressing this bottleneck concluding that even deployment of genetically modified microalgae with radically enhanced characteristics would leave a very significant logistical if not financial burden.

  5. Quantitative assessment of viable Cryptosporidium parvum load in commercial oysters (Crassostrea virginica) in the Chesapeake Bay.

    Science.gov (United States)

    Graczyk, Thaddeus K; Lewis, Earl J; Glass, Gregory; Dasilva, Alexandre J; Tamang, Leena; Girouard, Autumn S; Curriero, Frank C

    2007-01-01

    The epidemiological importance of increasing reports worldwide on Cryptosporidium contamination of oysters remains unknown in relation to foodborne cryptosporidiosis. Thirty market-size oysters (Crassostrea virginica), collected from each of 53 commercial harvesting sites in Chesapeake Bay, MD, were quantitatively tested in groups of six for Cryptosporidium sp. oocysts by immunofluorescent antibody (IFA). After IFA analysis, the samples were retrospectively retested for viable Cryptosporidium parvum oocysts by combined fluorescent in situ hybridization (FISH) and IFA. The mean cumulative numbers of Cryptosporidium sp. oocysts in six oysters (overall, 42.1+/-4.1) were significantly higher than in the numbers of viable C. parvum oocysts (overall, 28.0+/-2.9). Of 265 oyster groups, 221 (83.4%) contained viable C. parvum oocysts, and overall, from 10-32% (mean, 23%) of the total viable oocysts were identified in the hemolymph as distinct from gill washings. The amount of viable C. parvum oocysts was not related to oyster size or to the level of fecal coliforms at the sampling site. This study demonstrated that, although oysters are frequently contaminated with oocysts, the levels of viable oocysts may be too low to cause infection in healthy individuals. FISH assay for identification can be retrospectively applied to properly stored samples.

  6. How Close We Are to Achieving Commercially Viable Large-Scale Photobiological Hydrogen Production by Cyanobacteria: A Review of the Biological Aspects

    Science.gov (United States)

    Sakurai, Hidehiro; Masukawa, Hajime; Kitashima, Masaharu; Inoue, Kazuhito

    2015-01-01

    Photobiological production of H2 by cyanobacteria is considered to be an ideal source of renewable energy because the inputs, water and sunlight, are abundant. The products of photobiological systems are H2 and O2; the H2 can be used as the energy source of fuel cells, etc., which generate electricity at high efficiencies and minimal pollution, as the waste product is H2O. Overall, production of commercially viable algal fuels in any form, including biomass and biodiesel, is challenging, and the very few systems that are operational have yet to be evaluated. In this paper we will: briefly review some of the necessary conditions for economical production, summarize the reports of photobiological H2 production by cyanobacteria, present our schemes for future production, and discuss the necessity for further progress in the research needed to achieve commercially viable large-scale H2 production. PMID:25793279

  7. On-Chip Dielectrophoretic Separation and Concentration of Viable, Non-Viable and Viable but Not Culturable (VBNC) Escherichia coli

    Energy Technology Data Exchange (ETDEWEB)

    Packard, M M; Shusteff, M; Alocilja, E C

    2012-04-12

    Although bacterial culture remains the gold standard for detection of viable bacteria in environmental specimens, the typical time requirement of twenty-four hours can delay and even jeopardize appropriate public health intervention. In addition, culture is incapable of detecting viable but not culturable (VBNC) species. Conversely, nucleic acid and antibody-based methods greatly decrease time to detection but rarely characterize viability of the bacteria detected. Through selection by membrane permeability, the method described in this work employs positive dielectrophoresis (pDEP) for separation and purification of viable and VBNC species from water and allows concentration of bacteria for downstream applications.

  8. Commercializing Biorefinery Technology: A Case for the Multi-Product Pathway to a Viable Biorefinery

    Directory of Open Access Journals (Sweden)

    Shijie Liu

    2011-11-01

    Full Text Available While there may be many reasons why very interesting science ideas never reach commercial practice, one of the more prevalent is that the reaction or process, which is scientifically possible, cannot be made efficient enough to achieve economic viability. One pathway to economic viability for many business sectors is the multi-product portfolio. Research, development, and deployment of viable biorefinery technology must meld sound science with engineering and business economics. It is virtually axiomatic that increased value can be generated by isolating relatively pure substances from heterogeneous raw materials. Woody biomass is a heterogeneous raw material consisting of the major structural components, cellulose, lignin, and hemicelluloses, as well as minor components, such as extractives and ash. Cellulose is a linear homopolymer of D-glucopyrano-units with β-D(1®4 connections and is the wood component most resistant to chemical and biological degradation. Lignin is a macromolecule of phenylpropanoid units, second to cellulose in bio-resistance, and is the key component that is sought for removal from woody biomass in chemical pulping. Hemicelluloses are a collection of heteropolysaccharides, comprised mainly of 5- and 6-carbon sugars. Extractives, some of which have high commercial value, are a collection of low molecular weight organic and inorganic woody materials that can be removed, to some extent, under mild conditions. Applied Biorefinery Sciences, LLC (a private, New York, USA based company is commercializing a value-optimization pathway (the ABS Process™ for generating a multi-product portfolio by isolating and recovering homogeneous substances from each of the above mentioned major and minor woody biomass components. The ABS Process™ incorporates the patent pending, core biorefinery technology, “hot water extraction”, as developed at the State University of New York College of Environmental Science and Forestry (SUNY

  9. Polymerase chain reaction-based discrimination of viable from non-viable Mycoplasma gallisepticum

    Directory of Open Access Journals (Sweden)

    Ching Giap Tan

    2014-09-01

    Full Text Available The present study was based on the reverse transcription polymerase chain reaction (RT-PCR of the 16S ribosomal nucleic acid (rRNA of Mycoplasma for detection of viable Mycoplasma gallisepticum. To determine the stability of M. gallisepticum 16S rRNA in vitro, three inactivation methods were used and the suspensions were stored at different temperatures. The 16S rRNA of M. gallisepticum was detected up to approximately 20–25 h at 37 °C, 22–25 h at 16 °C, and 23–27 h at 4 °C. The test, therefore, could detect viable or recently dead M. gallisepticum (< 20 h. The RT-PCR method was applied during an in vivo study of drug efficacy under experimental conditions, where commercial broiler-breeder eggs were inoculated with M. gallisepticum into the yolk. Hatched chicks that had been inoculated in ovo were treated with Macrolide 1. The method was then applied in a flock of day 0 chicks with naturally acquired vertical transmission of M. gallisepticum, treated with Macrolide 2. Swabs of the respiratory tract were obtained for PCR and RT-PCR evaluations to determine the viability of M. gallisepticum. This study proved that the combination of both PCR and RT-PCR enables detection and differentiation of viable from non-viable M. gallisepticum.

  10. From the lab to commercial reality with biobased adhesives for wood

    Science.gov (United States)

    Charles R. Frihart; Michael J. Birkeland

    2016-01-01

    Many technologies can be demonstrated in the laboratory to give products that meet performance standards, but there are many hurdles to overcome before these products are commercially viable. Demonstrating performance under simulated commercial processes conditions is the first key step to be accomplished through using appropriate adhesive application, furnish...

  11. Planning and Operation of Commercial Application Center

    International Nuclear Information System (INIS)

    Kim, Jun Yeon; Kim, Kye Ryung; Lee, Tae Joon; Lee, Jae Hyeong; Park, Je Won; Lee, Jae Sang

    2003-06-01

    The objectives of this R and D project are as follows : First, transferring developed technologies to outside companies and operating technology market to vitalize technology transactions, Second, developing commercial application projects to transfer technologies for commercial purposes and to solve interface problems in commercial applications, Third, enhancing commercial utilizations of developed accelerator and beam utilization technologies, Finally. preparing infra-structures for the development of over 30 venture- businesses based on achieved technologies through the Proton Engineering Frontier Project

  12. Planning and Operation of Commercial Application Center

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jun Yeon; Kim, Kye Ryung; Lee, Tae Joon; Lee, Jae Hyeong; Park, Je Won; Lee, Jae Sang

    2003-06-15

    The objectives of this R and D project are as follows : First, transferring developed technologies to outside companies and operating technology market to vitalize technology transactions, Second, developing commercial application projects to transfer technologies for commercial purposes and to solve interface problems in commercial applications, Third, enhancing commercial utilizations of developed accelerator and beam utilization technologies, Finally. preparing infra-structures for the development of over 30 venture- businesses based on achieved technologies through the Proton Engineering Frontier Project.

  13. Commercial application of fault tree analysis

    International Nuclear Information System (INIS)

    Crosetti, P.A.; Bruce, R.A.

    1970-01-01

    The potential for general application of Fault Tree Analysis to commercial products appears attractive based not only on the successful extension from the aerospace safety technology to the nuclear reactor reliability and availability technology, but also because combinatorial hazards are common to commercial operations and therefore lend themselves readily to evaluation by Fault Tree Analysis. It appears reasonable to conclude that the technique has application within the commercial industrial community where the occurrence of a specified consequence or final event would be of sufficient concern to management to justify such a rigorous analysis as an aid to decision making. (U.S.)

  14. Commercial-grade motors in safety-related applications: Final report

    International Nuclear Information System (INIS)

    Holzman, P.M.

    1988-04-01

    The objective of this project was to discuss the process necessary to utilize commercial grade equipment in safety related applications and to provide utilities with guidance for accepting commercial grade motors for safety-related applications. The generic commercial-grade concepts presented in this report can be successfully applied to motors. Commercial grade item utilization has the greatest applicability to motors in ''mild'' environments, because these motors are essentially similar to commercial grade motors in materials, construction methods, and capabilities. The acceptance process is less applicable to motors that are subject to ''harsh'' environments during postulated accidents, because of the unique design features and testing required to qualify these motors

  15. Sycamore produces viable seed after six years

    Science.gov (United States)

    A. F. Ike

    1966-01-01

    In the early stages of any tree improvement program it is desirable to know how soon progenies of selected parents can themselves be included in a breeding program. How soon will they produce viable pollen and seed? In the case of sycamore (Platanus occidentalis L.), the information is meager: the Woody- Plant Seed Manual lists the minimum commercial seedbearing age...

  16. Non-viable antagonist cells are associated with reduced biocontrol performance by viable cells of the yeast Papiliotrema flavescens against Fusarium head blight of wheat.

    Science.gov (United States)

    Microbially-based plant disease control products have achieved commercial market success, but the efficacy of such biocontrol products is sometimes deemed inconsistent. Improper processing of harvested microbial biomass or long-term storage can reduce the proportion of viable cells and necessitate t...

  17. Commercial applications of inertial confinement fusion

    International Nuclear Information System (INIS)

    Booth, L.A.; Frank, T.G.

    1977-05-01

    This report describes the fundamentals of inertial-confinement fusion, some laser-fusion reactor (LFR) concepts, and attendant means of utilizing the thermonuclear energy for commercial electric power generation. In addition, other commercial energy-related applications, such as the production of fissionable fuels, of synthetic hydrocarbon-based fuels, and of process heat for a variety of uses, as well as the environmental and safety aspects of fusion energy, are discussed. Finally, the requirements for commercialization of laser fusion technologies are described

  18. Routes to a commercially viable PEM fuel cell stack

    Energy Technology Data Exchange (ETDEWEB)

    Newton, J.; Foster, S.E.; Hodgson, D.; Marrett, A.

    2002-07-01

    This report describes the results of a project to design and build a 10 kW{sub e} proton exchange membrane fuel cell (PEMFC) stack, including membrane electrode assemblies (MEAs), bipolar plates and stack hardware. The aim was to prove the design concept and to demonstrate functionality by operating the stack at >1 kW{sub e}/L and 500 W/kg for 200 hours operation. The project was extended to include the assembly and testing of two additional 1 kW{sub e} PEMFC stacks based on coated metal components. Low equivalent weight perfluorinated ionomer ion exchange membranes were prepared and were found to give a superior electrochemical performance to commercial materials. A technique to etch various stainless steel grades and control processes was successfully developed and optimised. Coatings for stainless steel and titanium were successfully developed and met the required performance criteria. All PEMFC stack components were selected and designed to enable subsequent commercial manufacture.

  19. Optical intersatellite links - Application to commercial satellite communications

    Science.gov (United States)

    Paul, D.; Faris, F.; Garlow, R.; Inukai, T.; Pontano, B.; Razdan, R.; Ganz, Aura; Caudill, L.

    1992-01-01

    Application of optical intersatellite links for commercial satellite communications services is addressed in this paper. The feasibility of commercialization centers around basic issues such as the need and derived benefits, implementation complexity and overall cost. In this paper, commercialization of optical ISLs is assessed in terms of the services provided, systems requirements and feasibility of appropriate technology. Both long- and short-range ISLs for GEO-GEO, GEO-LEO and LEO applications are considered. Impact of systems requirements on the payload design and use of advanced technology in reducing its mass, power, and volume requirements are discussed.

  20. Dye Sensitized Solar Cells for Economically Viable Photovoltaic Systems.

    Science.gov (United States)

    Jung, Hyun Suk; Lee, Jung-Kun

    2013-05-16

    TiO2 nanoparticle-based dye sensitized solar cells (DSSCs) have attracted a significant level of scientific and technological interest for their potential as economically viable photovoltaic devices. While DSSCs have multiple benefits such as material abundance, a short energy payback period, constant power output, and compatibility with flexible applications, there are still several challenges that hold back large scale commercialization. Critical factors determining the future of DSSCs involve energy conversion efficiency, long-term stability, and production cost. Continuous advancement of their long-term stability suggests that state-of-the-art DSSCs will operate for over 20 years without a significant decrease in performance. Nevertheless, key questions remain in regards to energy conversion efficiency improvements and material cost reduction. In this Perspective, the present state of the field and the ongoing efforts to address the requirements of DSSCs are summarized with views on the future of DSSCs.

  1. 40 CFR 171.3 - Categorization of commercial applicators of pesticides.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Categorization of commercial applicators of pesticides. 171.3 Section 171.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS CERTIFICATION OF PESTICIDE APPLICATORS § 171.3 Categorization of commercial...

  2. Layered Thermal Insulation Systems for Industrial and Commercial Applications

    Science.gov (United States)

    Fesmire, James E.

    2015-01-01

    From the high performance arena of cryogenic equipment, several different layered thermal insulation systems have been developed for industrial and commercial applications. In addition to the proven areas in cold-work applications for piping and tanks, the new Layered Composite Insulation for Extreme Environments (LCX) has potential for broader industrial use as well as for commercial applications. The LCX technology provides a unique combination of thermal, mechanical, and weathering performance capability that is both cost-effective and enabling. Industry applications may include, for example, liquid nitrogen (LN2) systems for food processing, liquefied natural gas (LNG) systems for transportation or power, and chilled water cooling facilities. Example commercial applications may include commercial residential building construction, hot water piping, HVAC systems, refrigerated trucks, cold chain shipping containers, and a various consumer products. The LCX system is highly tailorable to the end-use application and can be pre-fabricated or field assembled as needed. Product forms of LCX include rigid sheets, semi-flexible sheets, cylindrical clam-shells, removable covers, or flexible strips for wrapping. With increasing system control and reliability requirements as well as demands for higher energy efficiencies, thermal insulation in harsh environments is a growing challenge. The LCX technology grew out of solving problems in the insulation of mechanically complex cryogenic systems that must operate in outdoor, humid conditions. Insulation for cold work includes equipment for everything from liquid helium to chilled water. And in the middle are systems for LNG, LN2, liquid oxygen (LO2), liquid hydrogen (LH2) that must operate in the ambient environment. Different LCX systems have been demonstrated for sub-ambient conditions but are capable of moderately high temperature applications as well.

  3. Theoretical and Practical Aspects Regarding the Nulity of Commercial Companies

    Directory of Open Access Journals (Sweden)

    Cornelia Lefter

    2009-11-01

    Full Text Available The absence of a Romanian legal definition of the concept of nullity of commercial companies arouses a lot of questions. The delimitation of this concept is very important for a correct establishment of its field of application. In other words, are the cases of nullity of commercial companies regulated only by Law no. 31/1990 or by the provisions of common law as well?Started from the fact that the nullity is not considered by the legislator a simple sanction applicable to the juridical acts but it affects directly the existence of the company and becomes a means to sanction the creation of a legal person by disregarding the imperative legal provisions, we analyzed firstly the Romanian (II and the EU legal provisions regarding the nullity of commercial companies. The elements of this analyze helped us to qualify the nullity of commercial companies and its effect (III. Finally, through the conclusion formulated we hope to call the attention on the fact that a company, even created through the non-observance of the legal rules, can be viable from economic point of view and it is senseless to make it disappearance.

  4. Nuclear Analytical Techniques for Commercial Applications in China

    International Nuclear Information System (INIS)

    Chai, Z.; Zhang, Z.; Feng, S.; Yang, J.; Ouyang, H.; Feng, X.; Mao, X.

    2013-01-01

    Since the establishment of the first Chinese nuclear reactor and accelerator in 1958, the nuclear analytical techniques (NATs) in China have dramatically developed in past half century. Nowadays 10 research nuclear reactors and over 100 small accelerators are available in China. Roughly, about 50 % of the machine time is applied for commercial purpose at the moment. The versatile nuclear analytical methods, mainly NAA, PIXE, XRF, etc., in China have been and are being applied widely and extensively in the following three fields: scientific, training, and commercial. This paper will briefly describe the past experience and present status about NATs for commercial applications. Some practical examples to demonstrate the role of NATs in this aspect will be given as well. Basically, the NATs used for the commercial applications in China can be divided into two types, i.e. off-line and on-line. The former mainly includes instrumental neutron activation analysis (INAA) for compositional determination, particle induced X-ray emission (PIXE) also for compositional analysis, accelerator-based mass-spectrometry (AMS) for analysis of C-14, Be-7, Cl-36 and other long-lived radioactive nuclides, solid state nuclear track detector

  5. Apply Pesticides Correctly: A Guide for Commercial Applicators.

    Science.gov (United States)

    Environmental Protection Agency, Washington, DC.

    This document provides practical information needed by commercial pesticide applicators to meet the minimum Federal regulation requirements for the use of various pesticides. The text and accompanying illustrations cover the seven major topics of pests, pest control, pesticides, labels and labeling, using pesticides safely, application equipment,…

  6. Minimum Viable Product and the Importance of Experimentation in Technology Startups

    Directory of Open Access Journals (Sweden)

    Dobrila Rancic Moogk

    2012-03-01

    Full Text Available Entrepreneurs are often faced with limited resources in their quest to commercialize new technology. This article presents the model of a lean startup, which can be applied to an organization regardless of its size or environment. It also emphasizes the conditions of extreme uncertainty under which the commercialization of new technology is carried out. The lean startup philosophy advocates efficient use of resources by introducing a minimum viable product to the market as soon as possible in order to test its value and the entrepreneur’s growth projections. This testing is done by running experiments that examine the metrics relevant to three distinct types of the growth. These experiments bring about accelerated learning to help reduce the uncertainty that accompanies commercialization projects, thereby bringing the resulting new technology to market faster.

  7. Power system requirements and concepts for a commercially viable lunar base architecture

    Science.gov (United States)

    Lenard, Roger X.; Binder, Alan B.

    1999-01-01

    Historically, space exploration has been the province of governments and major agencies within those governmental entities. Recent advances in the state-of-the-art in many subsystem technology areas and the revealed inadequacies of governments to singlehandedly underwrite major exploration ventures present the potential to expand the venue of space exploration to the commercial sector. Further, major international projects such as the International Space Station have revealed weaknesses in both international financing and management of such projects. Cost overruns are the rule and significant schedule slips and/or failures to deliver have resulted in an enormously costly and delayed program. The exorbitant costs have stymied exploration ventures beyond Earth orbit. There are many potential advantages to a commercial operation including cost, schedule and a distinct customer orientation to services. The objective of this paper is to describe the first phase of a phased strawman commercial lunar base concept which operates as a user facility for governmental entities, corporations and companies. The paper will discuss the power system options and conditions under which such a base can be made to become profitable.

  8. Breaking down the barriers to commercialization of fuel cells in transportation through Government - industry R&D programs

    Energy Technology Data Exchange (ETDEWEB)

    Chalk, S.G. [Dept. of Energy, Washington, DC (United States); Venkateswaran, S.R. [Energetics, Inc., Columbia, MD (United States)

    1996-12-31

    PEM fuel cell technology is rapidly emerging as a viable propulsion alternative to the internal combustion engine. Fuel cells offer the advantages of low emissions, high efficiency, fuel flexibility, quiet and continuous operation, and modularity. Over the last decade, dramatic advances have been achieved in the performance and cost of PEM fuel cell technologies for automotive applications. However, significant technical barriers remain to making fuel cell propulsion systems viable alternatives to the internal combustion engine. This paper focuses on the progress achieved and remaining technical barriers while highlighting Government-industry R&D efforts that are accelerating fuel cell technology toward commercialization.

  9. Commercial grade item (CGI) dedication of generators for nuclear safety related applications

    International Nuclear Information System (INIS)

    Das, R.K.; Hajos, L.G.

    1993-01-01

    The number of nuclear safety related equipment suppliers and the availability of spare and replacement parts designed specifically for nuclear safety related application are shrinking rapidly. These have made it necessary for utilities to apply commercial grade spare and replacement parts in nuclear safety related applications after implementing proper acceptance and dedication process to verify that such items conform with the requirements of their use in nuclear safety related application. The general guidelines for the commercial grade item (CGI) acceptance and dedication are provided in US Nuclear Regulatory Commission (NRC) Generic Letters and Electric Power Research Institute (EPRI) Report NP-5652, Guideline for the Utilization of Commercial Grade Items in Nuclear Safety Related Applications. This paper presents an application of these generic guidelines for procurement, acceptance, and dedication of a commercial grade generator for use as a standby generator at Salem Generating Station Units 1 and 2. The paper identifies the critical characteristics of the generator which once verified, will provide reasonable assurance that the generator will perform its intended safety function. The paper also delineates the method of verification of the critical characteristics through tests and provide acceptance criteria for the test results. The methodology presented in this paper may be used as specific guidelines for reliable and cost effective procurement and dedication of commercial grade generators for use as standby generators at nuclear power plants

  10. 77 FR 30021 - Agency Information Collection Activities: Application To Use the Automated Commercial Environment...

    Science.gov (United States)

    2012-05-21

    ... Activities: Application To Use the Automated Commercial Environment (ACE) AGENCY: U.S. Customs and Border...: Application to Use the Automated Commercial Environment (ACE). This is a proposed extension of an information... Environment (ACE) is a trade processing system that will eventually replace the Automated Commercial System...

  11. A global reference database from very high resolution commercial satellite data and methodology for application to Landsat derived 30 m continuous field tree cover data

    Science.gov (United States)

    Pengra, Bruce; Long, Jordan; Dahal, Devendra; Stehman, Stephen V.; Loveland, Thomas R.

    2015-01-01

    The methodology for selection, creation, and application of a global remote sensing validation dataset using high resolution commercial satellite data is presented. High resolution data are obtained for a stratified random sample of 500 primary sampling units (5 km  ×  5 km sample blocks), where the stratification based on Köppen climate classes is used to distribute the sample globally among biomes. The high resolution data are classified to categorical land cover maps using an analyst mediated classification workflow. Our initial application of these data is to evaluate a global 30 m Landsat-derived, continuous field tree cover product. For this application, the categorical reference classification produced at 2 m resolution is converted to percent tree cover per 30 m pixel (secondary sampling unit)for comparison to Landsat-derived estimates of tree cover. We provide example results (based on a subsample of 25 sample blocks in South America) illustrating basic analyses of agreement that can be produced from these reference data. Commercial high resolution data availability and data quality are shown to provide a viable means of validating continuous field tree cover. When completed, the reference classifications for the full sample of 500 blocks will be released for public use.

  12. Commercializing fuel cells: managing risks

    Science.gov (United States)

    Bos, Peter B.

    Commercialization of fuel cells, like any other product, entails both financial and technical risks. Most of the fuel cell literature has focussed upon technical risks, however, the most significant risks during commercialization may well be associated with the financial funding requirements of this process. Successful commercialization requires an integrated management of these risks. Like any developing technology, fuel cells face the typical 'Catch-22' of commercialization: "to enter the market, the production costs must come down, however, to lower these costs, the cumulative production must be greatly increased, i.e. significant market penetration must occur". Unless explicit steps are taken to address this dilemma, fuel cell commercialization will remain slow and require large subsidies for market entry. To successfully address this commercialization dilemma, it is necessary to follow a market-driven commercialization strategy that identifies high-value entry markets while minimizing the financial and technical risks of market entry. The financial and technical risks of fuel cell commercialization are minimized, both for vendors and end-users, with the initial market entry of small-scale systems into high-value stationary applications. Small-scale systems, in the order of 1-40 kW, benefit from economies of production — as opposed to economies to scale — to attain rapid cost reductions from production learning and continuous technological innovation. These capital costs reductions will accelerate their commercialization through market pull as the fuel cell systems become progressively more viable, starting with various high-value stationary and, eventually, for high-volume mobile applications. To facilitate market penetration via market pull, fuel cell systems must meet market-derived economic and technical specifications and be compatible with existing market and fuels infrastructures. Compatibility with the fuels infrastructure is facilitated by a

  13. Next-generation batteries and fuel cells for commercial, military, and space applications

    CERN Document Server

    Jha, A R

    2012-01-01

    Distilling complex theoretical physical concepts into an understandable technical framework, Next-Generation Batteries and Fuel Cells for Commercial, Military, and Space Applications describes primary and secondary (rechargeable) batteries for various commercial, military, spacecraft, and satellite applications for covert communications, surveillance, and reconnaissance missions. It emphasizes the cost, reliability, longevity, and safety of the next generation of high-capacity batteries for applications where high energy density, minimum weight and size, and reliability in harsh conditions are

  14. Commercial Off-The-Shelf (COTS) Electronics Reliability for Space Applications

    Science.gov (United States)

    Pellish, Jonathan

    2018-01-01

    This presentation describes the accelerating use of Commercial off the Shelf (COTS) parts in space applications. Component reliability and threats in the context of the mission, environment, application, and lifetime. Provides overview of traditional approaches applied to COTS parts in flight applications, and shows challenges and potential paths forward for COTS systems in flight applications it's all about data!

  15. Commercial applications of perfluorocarbon tracer (PFT) technology

    International Nuclear Information System (INIS)

    Dietz, R.N.

    1991-06-01

    Tracer technology can be successfully applied to many leak-checking and monitoring evaluations of operating systems (e.g., building HVACs), manufacturing processes and products (e.g., air conditioners), and subsurface components and systems (e.g., underground storage tanks). Perfluorocarbon tracer (PFT) technology is the most sensitive of all tracer technologies because the ambient background levels of the five (5) routinely-used PFTs are in the range of parts per 10 15 parts of air (i.e., parts per quadrillion-ppq) and this technology's instrumentation can measure down to those levels. The effectiveness of this technology is achieved both in terms of cost (very little PFT need to be used) and detectability; for example, very small leaks can be rapidly detected. The PFT compounds, which are environmentally and biologically safe to use, are commercially available as are the sampling and analysis instrumentation. This presentation concerns (1) the steps being taken to commercialize this technology, (2) new applications of processes currently under study, and (3) applications in areas of use that will be particularly beneficial to the environment. 21 refs., 2 figs., 2 tabs

  16. Separation of viable and non-viable tomato (Solanum lycopersicum L.) seeds using single seed near-infrared spectroscopy

    DEFF Research Database (Denmark)

    Shrestha, Santosh; Deleuran, Lise Christina; Gislum, René

    2017-01-01

    Single seed near-infrared (NIR) spectroscopy is a non-destructive technology commonly used for predicting lipids, proteins, carbohydrates and water content of agricultural products. The aim of the current study is to investigate the prospects of NIR spectroscopy in classifying viable and non...... identified as important for classification of viable and non-viable tomato seeds by iPLS-DA. The sensitivity i.e. ability to correctly identify the positive samples and specificity i.e. ability to reject the negative samples of the (iPLS-DA) model on identified spectral regions for prediction of viable......-viable tomato seeds of two cultivars using chemometrics. The data exploration were performed by principal component analysis (PCA). Subsequently, viable and non-viable seeds were classified by partial least squares-discriminant analysis (PLS-DA) and interval PLS-DA (iPLS-DA). The indication of clustering...

  17. 48 CFR 212.504 - Applicability of certain laws to subcontracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to subcontracts for the acquisition of commercial items. 212.504 Section 212.504 Federal... PLANNING ACQUISITION OF COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items 212.504 Applicability of certain laws to subcontracts for the acquisition of commercial items. (a...

  18. Application of adaptive antenna techniques to future commercial satellite communication

    Science.gov (United States)

    Ersoy, L.; Lee, E. A.; Matthews, E. W.

    1987-01-01

    The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further sub-divided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

  19. 48 CFR 12.504 - Applicability of certain laws to subcontracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to subcontracts for the acquisition of commercial items. 12.504 Section 12.504 Federal Acquisition... Applicability of Certain Laws to the Acquisition of Commercial Items and Commercially Available Off-The-Shelf Items 12.504 Applicability of certain laws to subcontracts for the acquisition of commercial items. (a...

  20. Trends in genetic patent applications: The commercialization of academic intellectual property

    NARCIS (Netherlands)

    Kers, J.G.; van Burg, J.C.; Stoop, T.; Cornel, M.C.

    2014-01-01

    We studied trends in genetic patent applications in order to identify the trends in the commercialization of research findings in genetics. To define genetic patent applications, the European version (ECLA) of the International Patent Classification (IPC) codes was used. Genetic patent applications

  1. ERAST: Scientific Applications and Technology Commercialization

    Science.gov (United States)

    Hunley, John D. (Compiler); Kellogg, Yvonne (Compiler)

    2000-01-01

    This is a conference publication for an event designed to inform potential contractors and appropriate personnel in various scientific disciplines that the ERAST (Environmental Research Aircraft and Sensor Technology) vehicles have reached a certain level of maturity and are available to perform a variety of missions ranging from data gathering to telecommunications. There are multiple applications of the technology and a great many potential commercial and governmental markets. As high altitude platforms, the ERAST vehicles can gather data at higher resolution than satellites and can do so continuously, whereas satellites pass over a particular area only once each orbit. Formal addresses are given by Rich Christiansen, (Director of Programs, NASA Aerospace Technology Ent.), Larry Roeder, (Senior Policy Advisor, U.S. Dept. of State), and Dr. Marianne McCarthy, (DFRC Education Dept.). The Commercialization Workshop is chaired by Dale Tietz (President, New Vista International) and the Science Workshop is chaired by Steve Wegener, (Deputy Manager of NASA ERAST, NASA Ames Research Center.

  2. NASA Technology Applications Team: Commercial applications of aerospace technology

    Science.gov (United States)

    1994-01-01

    The Research Triangle Institute (RTI) Team has maintained its focus on helping NASA establish partnerships with U.S. industry for dual use development and technology commercialization. Our emphasis has been on outcomes, such as licenses, industry partnerships and commercialization of technologies, that are important to NASA in its mission of contributing to the improved competitive position of U.S. industry. The RTI Team has been successful in the development of NASA/industry partnerships and commercialization of NASA technologies. RTI ongoing commitment to quality and customer responsiveness has driven our staff to continuously improve our technology transfer methodologies to meet NASA's requirements. For example, RTI has emphasized the following areas: (1) Methodology For Technology Assessment and Marketing: RTI has developed and implemented effective processes for assessing the commercial potential of NASA technologies. These processes resulted from an RTI study of best practices, hands-on experience, and extensive interaction with the NASA Field Centers to adapt to their specific needs. (2) Effective Marketing Strategies: RTI surveyed industry technology managers to determine effective marketing tools and strategies. The Technology Opportunity Announcement format and content were developed as a result of this industry input. For technologies with a dynamic visual impact, RTI has developed a stand-alone demonstration diskette that was successful in developing industry interest in licensing the technology. And (3) Responsiveness to NASA Requirements: RTI listened to our customer (NASA) and designed our processes to conform with the internal procedures and resources at each NASA Field Center and the direction provided by NASA's Agenda for Change. This report covers the activities of the Research Triangle Institute Technology Applications Team for the period 1 October 1993 through 31 December 1994.

  3. Prototype to product—developing a commercially viable neural prosthesis

    Science.gov (United States)

    Seligman, Peter

    2009-12-01

    The Cochlear implant or 'Bionic ear' is a device that enables people who do not get sufficient benefit from a hearing aid to communicate with the hearing world. The Cochlear implant is not an amplifier, but a device that electrically stimulates the auditory nerve in a way that crudely mimics normal hearing, thus providing a hearing percept. Many recipients are able to understand running speech without the help of lipreading. Cochlear implants have reached a stage of maturity where there are now 170 000 recipients implanted worldwide. The commercial development of these devices has occurred over the last 30 years. This development has been multidisciplinary, including audiologists, engineers, both mechanical and electrical, histologists, materials scientists, physiologists, surgeons and speech pathologists. This paper will trace the development of the device we have today, from the engineering perspective. The special challenges of designing an active device that will work in the human body for a lifetime will be outlined. These challenges include biocompatibility, extreme reliability, safety, patient fitting and surgical issues. It is emphasized that the successful development of a neural prosthesis requires the partnership of academia and industry.

  4. Commercial application of bacterial heap leaching in Ganzhou uranium mine

    International Nuclear Information System (INIS)

    Liu Jian; Fan Baotuan; Meng Yunsheng; Xiao Jinfeng; Chen Sencai; Wu Jinjing; Liu Chengwu; Wu Yichang; Zeng Ruilong

    2003-01-01

    In this paper the situation of commercial application on bacterial heap leaching in Ganzhou Uranium Mine is introduced, and the construction of biomembrane oxidizing tank, regeneration and recycled utilization of barren solution are summarized. Total five heaps, 18436 t, uranium ore are leached by bacteria during the half of a year. The result is consistent with that of commercial experiment. The technology of bacterial heap leaching is more perfected

  5. The commercialization of natural gas for vehicles

    International Nuclear Information System (INIS)

    Wray, P.

    1997-01-01

    A successful NGV industry depends upon the skilled use of prime geographic and economic drivers. But a vital ingredient to a sustained and profitable industry is the pioneering example of the gas suppliers and the combined commercial skills of fleet operators equipment suppliers and government. The use of natural gas for vehicles must be long-term commercially viable both for the vehicles whole life cost and the refuelling stations capital investment. (au)

  6. Building Viable and Sustainable Regional Netchains: Case Studies of Regional Pork Netchains in Spain, Germany, and The Netherlands

    Directory of Open Access Journals (Sweden)

    Rannia Nijhoff‐Savvaki

    2012-06-01

    Full Text Available The present paper aims to give insight into critical issues contributing to the successful building of viable and sustainable regional netchains, focussing on chain governance mechanisms (coordination mechanisms, quality management systems, information systems and social embedding. It uses three representative case studies from the regional pork sector in Spain, Germany, and The Netherlands, illustrating different trajectories to commercially viable and sustainable regional netchains. By analysing the cases on each critical aspect, the present paper describes important issues and proposes specific elements of further research, including on the roles for(nongovernmental organisations.

  7. The Conceptual Mechanism for Viable Organizational Learning Based on Complex System Theory and the Viable System Model

    Science.gov (United States)

    Sung, Dia; You, Yeongmahn; Song, Ji Hoon

    2008-01-01

    The purpose of this research is to explore the possibility of viable learning organizations based on identifying viable organizational learning mechanisms. Two theoretical foundations, complex system theory and viable system theory, have been integrated to provide the rationale for building the sustainable organizational learning mechanism. The…

  8. Controlling active cabin suspensions in commercial vehicles

    NARCIS (Netherlands)

    Evers, W.J.E.; Besselink, I.J.M.; Teerhuis, A.P.; Knaap, van der A.C.M.; Nijmeijer, H.

    2009-01-01

    The field of automotive suspensions is changing. Semi-active and active suspensions are starting to become viable options for vehicle designers. Suspension design for commercial vehicles is especially interesting given its potential. An active cabin suspension for a heavy-duty truck is considered,

  9. Fuel cells are a commercially viable alternative for the production of "clean" energy.

    Science.gov (United States)

    Niakolas, Dimitris K; Daletou, Maria; Neophytides, Stylianos G; Vayenas, Constantinos G

    2016-01-01

    Fuel cells present a highly efficient and environmentally friendly alternative technology for decentralized energy production. The scope of the present study is to provide an overview of the technological and commercialization readiness level of fuel cells. Specifically, there is a brief description of their general advantages and weaknesses in correlation with various technological actions and political strategies, which are adopted towards their proper positioning in the global market. Some of the most important key performance indicators are also discussed, alongside with a few examples of broad commercialization. It is concluded that the increasing number of companies which utilize and invest on this technology, in combination with the supply chain improvements and the concomitant technological maturity and recognition, reinforce the fuel cell industry so as to become well-aligned for global success.

  10. 48 CFR 12.503 - Applicability of certain laws to Executive agency contracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to Executive agency contracts for the acquisition of commercial items. 12.503 Section 12.503... COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items and Commercially... acquisition of commercial items. (a) The following laws are not applicable to Executive agency contracts for...

  11. A hybrid life cycle assessment of the vehicle-to-grid application in light duty commercial fleet

    International Nuclear Information System (INIS)

    Zhao, Yang; Tatari, Omer

    2015-01-01

    The vehicle-to-grid system is an approach utilizing the idle battery capacity of electric vehicles while they are parked to provide supplementary energy to the power grid. As electrification continues in light duty vehicle fleets, the application of vehicle-to-grid systems for commercial delivery truck fleets can provide extra revenue for fleet owners, and also has significant potential for reducing greenhouse gas emissions from the electricity generation sector. In this study, an economic input–output based hybrid life cycle assessment is conducted to analyze the potential greenhouse gas emissions emission savings from the use of the vehicle-to-grid system, as well as the possible emission impacts caused by battery degradation. A Monte Carlo simulation was performed to address the uncertainties that lie in the electricity exchange amount of the vehicle-to-grid service as well as the battery life of the electric vehicles. The results of this study showed that extended range electric vehicles and battery electric vehicles are both viable regulation service providers for saving greenhouse gas emissions from electricity generation if the battery wear-out from regulation services is assumed to be minimal, but the vehicle-to-grid system becomes less attractive at higher battery degradation levels. - Highlights: • The commercial delivery trucks are studied as vehicle-to-grid service providers. • Hybrid life cycle assessment is conducted to evaluate emission mitigation. • Battery degradation level and corresponding emissions and cost are evaluated. • Vehicle-to-grid service is shown to have significant emission saving effect.

  12. Application of the iron-enriched basalt waste form for immobilizing commercial transuranic waste

    International Nuclear Information System (INIS)

    Owen, D.E.

    1981-08-01

    The principal sources of commercial transuranic (TRU) waste in the United States are identified. The physical and chemical nature of the wastes from these sources are discussed. The fabrication technique and properties of iron-enriched basalt, a rock-like waste form developed for immobilizing defense TRU wastes, are discussed. The application of iron-enriched basalt to commercial TRU wastes is discussed. Review of commercial TRU wastes from mixed-oxide fuel fabrication, light water reactor fuel reprocessing, and miscellaneous medical, research, and industrial sources, indicates that iron-enriched basalt is suitable for most types of commercial TRU wastes. Noncombustible TRU wastes are dissolved in the high temperature, oxidizing iron-enriched basalt melt. Combustible TRU wastes are immobilized in iron-enriched basalt by incinerating the wastes and adding the TRU-bearing ash to the melt. Casting and controlled cooling of the melt produces a devitrified, rock-like iron-enriched basalt monolith. Recommendations are given for testing the applicability of iron-enriched basalt to commercial TRU wastes

  13. Bioreactors in tissue engineering - principles, applications and commercial constraints.

    Science.gov (United States)

    Hansmann, Jan; Groeber, Florian; Kahlig, Alexander; Kleinhans, Claudia; Walles, Heike

    2013-03-01

    Bioreactor technology is vital for tissue engineering. Usually, bioreactors are used to provide a tissue-specific physiological in vitro environment during tissue maturation. In addition to this most obvious application, bioreactors have the potential to improve the efficiency of the overall tissue-engineering concept. To date, a variety of bioreactor systems for tissue-specific applications have been developed. Of these, some systems are already commercially available. With bioreactor technology, various functional tissues of different types were generated and cultured in vitro. Nevertheless, these efforts and achievements alone have not yet led to many clinically successful tissue-engineered implants. We review possible applications for bioreactor systems within a tissue-engineering process and present basic principles and requirements for bioreactor development. Moreover, the use of bioreactor systems for the expansion of clinically relevant cell types is addressed. In contrast to cell expansion, for the generation of functional three-dimensional tissue equivalents, additional physical cues must be provided. Therefore, bioreactors for musculoskeletal tissue engineering are discussed. Finally, bioreactor technology is reviewed in the context of commercial constraints. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. 48 CFR 212.570 - Applicability of certain laws to contracts and subcontracts for the acquisition of commercially...

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items 212.570 Applicability of certain laws to contracts and... laws to contracts and subcontracts for the acquisition of commercially available off-the-shelf items...

  15. 77 FR 14535 - Agency Information Collection Activities: Application To Use the Automated Commercial Environment...

    Science.gov (United States)

    2012-03-12

    ... Activities: Application To Use the Automated Commercial Environment (ACE) AGENCY: U.S. Customs and Border... Commercial Environment (ACE). This request for comment is being made pursuant to the Paperwork Reduction Act... Number: None. Abstract: The Automated Commercial Environment (ACE) is a trade processing system that will...

  16. Commercial Application of In-Space Assembly

    Science.gov (United States)

    Lymer, John; Hanson, Mark; Tadros, Al; Boccio, Joel; Hollenstein, Bruno; Emerick, Ken; Doughtery, Sean; Doggett, Bill; Dorsey, John T.; King, Bruce D.; hide

    2016-01-01

    In-Space assembly (ISA) expands the opportunities for cost effective emplacement of systems in space. Currently, spacecraft are launched into space and deploy into their operational configuration through a carefully choreographed sequence of operations. The deployment operation dictates the arrangement of the primary systems on the spacecraft, limiting the ability to take full advantage of launch vehicles volume and mass capability. ISA enables vastly different spacecraft architectures and emplacement scenarios to be achieved, including optimal launch configurations ranging from single launch and assembly to on-orbit aggregation of multiple launches at different orbital locations and times. The spacecraft can be visited at different orbital locations and times to effect expansion and maintenance of an operational capability. To date, the primary application of ISA has been in large programs funded by government organizations, such as the International Space Station. Recently, Space Systems Loral (SSL) led a study funded by the Defense Advanced Research Projects Agency (DARPA), called Dragonfly, to investigate the commercial applicability and economic advantages of ISA. In the study, it was shown that ISA enables SSL to double the capability of a commercial satellite system by taking advantage of alternate packaging approaches for the reflectors. The study included an ultra-light-weight robotic system, derived from Mars manipulator designs, to complete assembly of portions of the antenna system using a tool derived from DARPA orbital express and National Aeronautics and Space Administration (NASA) automated structural assembly experience. The mechanical connector that enables robotic ISA takes advantage of decades of development by NASA from the 1970's to 1980's during the Space Station Freedom program, the precursor to the ISS. The mechanical connector was originally designed for rapid astronaut assembly while also providing a high quality structural connection

  17. The status of commercial and developmental HTS wires

    Energy Technology Data Exchange (ETDEWEB)

    Masur, L.J.; Buczek, D.; Harley, E.; Kodenkandath, T.; Li, X.; Lynch, J.; Nguyen, N.; Rupich, M.; Schoop, U.; Scudiere, J.; Siegal, E.; Thieme, C.; Verebelyi, D.; Zhang, W.; Kellers, J

    2003-10-15

    This paper provides an update on the development, performance and application of first and second generation high temperature superconductor (HTS) wires fabricated at American Superconductor (AMSC). First generation, multifilamentary composite wire is available commercially today in different viable product forms. This conductor carries 140 x the current of copper of the same cross-section, and is robust enough to stand tough industrial requirements. Second generation HTS wires, having a coated conductor composite architecture, are under development today and achieved substantial progress recently. AMSC's first generation wire will continue as the workhorse of the industry for the next 3-4 years while AMSC's second generation coated conductor wire is on track to be reproducible, uniform, scalable, and low cost. This paper provides a product differentiation with a view on the application of HTS wire in the electric power sector. Basic engineering data is reviewed that shall aid the engineer in the selection of the HTS wire product.

  18. New developments in nickel-hydrogen cell and battery design for commercial applications

    Energy Technology Data Exchange (ETDEWEB)

    Caldwell, D.B.; Fox, C.L.; Miller, L.E. [Eagle-Picher Industries, Inc., Joplin, MO (United States)

    1997-12-31

    Nickel-hydrogen (NiH{sub 2}) battery systems were first developed for space applications more than 20 years ago. Currently, they are being manufactured for commercial, terrestrial applications. The battery is ideal for commercial terrestrial energy storage applications because it offers a better potential cycle life than any other battery system and is maintenance free. A selection of low-cost components, electrodes, cell designs and battery designs are being tested to determine their feasibility for commercial applications. The dependent pressure vessel (DPV) design, developed by Eagle-Picher Industries, is the newest step in the continued development and evolution of the NiH{sub 2} system. The unique feature of the DPV cell design is the prismatic electrode stack which is more efficient than the cylindrical electrode stack. The electrode stack is the electrochemically active part of the cell. It contains nickel and hydrogen electrodes interspersed with an absorbent separator. DPV cells of two sizes, 40 and 60 Ah cells, have been developed. The DPV cell offers high specific energy at a reduced cost. The advanced DPV design also offers an efficient mechanical, electrical and thermal configuration and a reduced parts count. The design promotes compact, minimum volume packaging and weight efficiency. 8 refs., 7 figs.

  19. Cummins L10G in Kenworth truck 'viable today'

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    As the culmination of five years of developmental work by Cummins Engines, BC Research Inc., and BC Gas Utility Ltd., a T800 Kenworth truck was outfitted with a new Cummins L10G natural gas engine, and two lightweight fully -wrapped Dynetek cylinders; it was pronounced to be 'a viable clean truck today'. The L10G spark-ignited engine operates at a relatively high peak efficiency of 37 per cent and is commercially available to meet the current California Air Resources Board heavy duty vehicle emission standards without the use of a catalytic converter. The L10G engine produces no particulate emissions, a very significant advantage, in view of the fact that particulate emissions have been identified as major contributors to respiratory ailments

  20. Non-commercial vs. commercial clinical trials: a retrospective study of the applications submitted to a research ethics committee.

    Science.gov (United States)

    Fuentes Camps, Inmaculada; Rodríguez, Alexis; Agustí, Antonia

    2018-02-15

    There are many difficulties in undertaking independent clinical research without support from the pharmaceutical industry. In this retrospective observational study, some design characteristics, the clinical trial public register and the publication rate of noncommercial clinical trials were compared to those of commercial clinical trials. A total of 809 applications of drug-evaluation clinical trials were submitted from May 2004 to May 2009 to the research ethics committee of a tertiary hospital, and 16.3% of trials were noncommercial. They were mainly phase IV, multicentre national, and unmasked controlled trials, compared to the commercial trials that were mainly phase II or III, multicentre international, and double-blind masked trials. The commercial trials were registered and published more often than noncommercial trials. More funding for noncommercial research is still needed. The results of the research, commercial or noncommercial, should be disseminated in order not to compromise either its scientific or its social value. © 2018 The British Pharmacological Society.

  1. Application of IC Card License for Road Transportation in Commercial Vehicles Supervision and Service

    Directory of Open Access Journals (Sweden)

    Li Weiwei

    2016-01-01

    Full Text Available IC card electronic license for road transport includes the IC card commercial vehicle’s certificate and IC card practitioner’s qualification certificate. In China, the IC card electronic license for road transport is the electronic ID card which must be carried by each commercial vehicles and practitioners. This paper briefly introduces the basic situation, data format and security keys architecture of IC card electronic license for road transportation of China. In order to strengthen the supervision and service of commercial vehicles, this paper puts forward the overall application framework of IC card electronic license for road transport. The application examples of IC card license in the supervision of passenger station, dangerous goods transport management, governance overload and logistics park and port area management are discussed. The practical application results show that the application of IC card electronic license for road transport is an important technical means to improve the supervision ability and service quality of the road transportation industry.

  2. Technology requirements for commercial applications of inertial confinement fusion

    International Nuclear Information System (INIS)

    Frank, T.G.; Rossi, C.E.

    1981-01-01

    Current inertial confinement fusion (ICF) research is directed primarily at physics experiments intended to provide confidence in the scientific feasibility of the basic concept. In conjunction with these experiments, a variety of laser and particle beam drivers having potential for eventual use in fusion power plants is being developed. Expectations are that the scientific feasibility of ICF will be demonstrated in the latter part of the 1980s. At that time, the emphasis of the program will shift to engineering, economic, environmental, and licensing issues with the necessary technology development effort continuing into the early part of the next century. This paper discusses the technology requirements for the successive phases of engineering development leading to commercial application of ICF. The engineering areas requiring significant effort for ICF application include high average power driver development; pulsed high-energy power supply development; reactor cavity and heat transport system design; tritium extraction and control; commercial pellet development; pellet injection, tracking, and targeting systems design; materials radiation, fatigue, and corrosion behavior; and reactor plant systems integration and demonstration

  3. Technology leadership : a road map to commercially viable PEMFC stack technology

    Energy Technology Data Exchange (ETDEWEB)

    Stone, C. [Ballard Power Systems, Burnaby, BC (Canada)

    2005-07-01

    This abstract discussed recent advances in stack technology by Ballard Power Systems. The technology department of this Canadian-owned company exhibited the capability of a single proton exchange membrane fuel cell (PEMFC) stack design to demonstrate that cost reduction, freeze start capability from -20 degrees C and durability under an automotive dynamic operating cycle are comparable to that experienced by a fuel cell stack in an actual vehicle. A technology road map has been developed by the company to define a path to the commercial viability of the PEMFC stack by 2010. Key target parameters for cost reduction, durability, freeze start and stack power density were described in detail along with demonstrated historical capability and details of how the company will achieve its required targets. refs., tabs., figs.

  4. 48 CFR 212.503 - Applicability of certain laws to executive agency contracts for the acquisition of commercial items.

    Science.gov (United States)

    2010-10-01

    ... laws to executive agency contracts for the acquisition of commercial items. 212.503 Section 212.503... ACQUISITION PLANNING ACQUISITION OF COMMERCIAL ITEMS Applicability of Certain Laws to the Acquisition of Commercial Items 212.503 Applicability of certain laws to executive agency contracts for the acquisition of...

  5. Commercial Manure Applicators

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — This layer represents the office location for Commercial Manure Services (CMS). They transport, handle, store or apply manure for a fee. The company must be licensed...

  6. Limitations of Commercializing Fuel Cell Technologies

    Science.gov (United States)

    Nordin, Normayati

    2010-06-01

    Fuel cell is the technology that, nowadays, is deemed having a great potential to be used in supplying energy. Basically, fuel cells can be categorized particularly by the kind of employed electrolyte. Several fuel cells types which are currently identified having huge potential to be utilized, namely, Solid Oxide Fuel Cells (SOFC), Molten Carbonate Fuel Cells (MCFC), Alkaline Fuel Cells (AFC), Phosphoric Acid Fuel Cells (PAFC), Polymer Electron Membrane Fuel Cell (PEMFC), Direct Methanol Fuel Cells (DMFC) and Regenerative Fuel Cells (RFC). In general, each of these fuel cells types has their own characteristics and specifications which assign the capability and suitability of them to be utilized for any particular applications. Stationary power generations and transport applications are the two most significant applications currently aimed for the fuel cell market. It is generally accepted that there are lots of advantages if fuel cells can be excessively commercialized primarily in context of environmental concerns and energy security. Nevertheless, this is a demanding task to be accomplished, as there is some gap in fuel cells technology itself which needs a major enhancement. It can be concluded, from the previous study, cost, durability and performance are identified as the main limitations to be firstly overcome in enabling fuel cells technology become viable for the market.

  7. Viable Mycobacterium avium ssp. paratuberculosis isolated from calf milk replacer.

    Science.gov (United States)

    Grant, Irene R; Foddai, Antonio C G; Tarrant, James C; Kunkel, Brenna; Hartmann, Faye A; McGuirk, Sheila; Hansen, Chungyi; Talaat, Adel M; Collins, Michael T

    2017-12-01

    When advising farmers on how to control Johne's disease in an infected herd, one of the main recommendations is to avoid feeding waste milk to calves and instead feed calf milk replacer (CMR). This advice is based on the assumption that CMR is free of viable Mycobacterium avium ssp. paratuberculosis (MAP) cells, an assumption that has not previously been challenged. We tested commercial CMR products (n = 83) obtained from dairy farms around the United States by the peptide-mediated magnetic separation (PMS)-phage assay, PMS followed by liquid culture (PMS-culture), and direct IS900 quantitative PCR (qPCR). Conventional microbiological analyses for total mesophilic bacterial counts, coliforms, Salmonella, coagulase-negative staphylococci, streptococci, nonhemolytic Corynebacterium spp., and Bacillus spp. were also performed to assess the overall microbiological quality of the CMR. Twenty-six (31.3%) of the 83 CMR samples showed evidence of the presence of MAP. Seventeen (20.5%) tested positive for viable MAP by the PMS-phage assay, with plaque counts ranging from 6 to 1,212 pfu/50 mL of reconstituted CMR (average 248.5 pfu/50 mL). Twelve (14.5%) CMR samples tested positive for viable MAP by PMS-culture; isolates from all 12 of these samples were subsequently confirmed by whole-genome sequencing to be different cattle strains of MAP. Seven (8.4%) CMR samples tested positive for MAP DNA by IS900 qPCR. Four CMR samples tested positive by both PMS-based tests and 5 CMR samples tested positive by IS900 qPCR plus one or other of the PMS-based tests, but only one CMR sample tested positive by all 3 MAP detection tests applied. All conventional microbiology results were within current standards for whole milk powders. A significant association existed between higher total bacterial counts and presence of viable MAP indicated by either of the PMS-based assays. This represents the first published report of the isolation of viable MAP from CMR. Our findings raise concerns

  8. Review of Compact Commercial Accelerator Products and Applications.

    Science.gov (United States)

    Jongen, Y.

    1997-05-01

    Historically, particle accelerators were developed initially for nuclear, then for particle physics research. From this research resulted applications of accelerators in the field of medicine and industry. These application-oriented accelerators are generally built commercially, and they often emphasize other qualities than the accelerators for research. The research applications frequently require energies or beam qualities at the limit of the existing technologies. They offer the largest flexibility in term of particles and beam properties, but are more complex, more expensive and often require large and highly qualified staff to operate and maintain them. In contrast, most applications are done with low to moderate energy protons or electrons, but often with large average beam power. The accelerators are generally specialized for a specific application, and are therefore very simple and inexpensive to operate. The author will review some applications in the field of medicine, such as the production of radio-isotopes for medical diagnostic or the production of electrons, protons or fast neutron beams for cancer therapy. In the industrial field, high power electron beam are used for sterilization and for the modification of materials. Log No. 1001

  9. PMA-PhyloChip DNA Microarray to Elucidate Viable Microbial Community Structure

    Science.gov (United States)

    Venkateswaran, Kasthuri J.; Stam, Christina N.; Andersen, Gary L.; DeSantis, Todd

    2011-01-01

    Since the Viking missions in the mid-1970s, traditional culture-based methods have been used for microbial enumeration by various NASA programs. Viable microbes are of particular concern for spacecraft cleanliness, for forward contamination of extraterrestrial bodies (proliferation of microbes), and for crew health/safety (viable pathogenic microbes). However, a "true" estimation of viable microbial population and differentiation from their dead cells using the most sensitive molecular methods is a challenge, because of the stability of DNA from dead cells. The goal of this research is to evaluate a rapid and sensitive microbial detection concept that will selectively estimate viable microbes. Nucleic acid amplification approaches such as the polymerase chain reaction (PCR) have shown promise for reducing time to detection for a wide range of applications. The proposed method is based on the use of a fluorescent DNA intercalating agent, propidium monoazide (PMA), which can only penetrate the membrane of dead cells. The PMA-quenched reaction mixtures can be screened, where only the DNA from live cells will be available for subsequent PCR reaction and microarray detection, and be identified as part of the viable microbial community. An additional advantage of the proposed rapid method is that it will detect viable microbes and differentiate from dead cells in only a few hours, as opposed to less comprehensive culture-based assays, which take days to complete. This novel combination approach is called the PMA-Microarray method. DNA intercalating agents such as PMA have previously been used to selectively distinguish between viable and dead bacterial cells. Once in the cell, the dye intercalates with the DNA and, upon photolysis under visible light, produces stable DNA adducts. DNA cross-linked in this way is unavailable for PCR. Environmental samples suspected of containing a mixture of live and dead microbial cells/spores will be treated with PMA, and then incubated

  10. Evaluation of commercial and sulfated ZrO_2 aiming application catalysis

    International Nuclear Information System (INIS)

    Silva, F.N.; Dantas, J.; Costa, A.C.F.M.; Pallone, E.M.J.A.; Dutra, R.C.L.

    2014-01-01

    This study evaluates the performance of commercial and sulfated ZrO_2 for future application in catalysis. Commercial ZrO_2 was provided by the company Saint-Gobain Zirpro. The sulfation occurred with SO_4"-"2 ion content of 30% compared to the mass of ZrO_2. The samples were characterized by XRD, FTIR, EDX and GD. The results revealed the formation of a monoclinic phase for the commercial sample, and a monoclinic major phase with tetragonal traces for the sulfated sample. The commercial ZrO_2 showed a narrow, bimodal and asymmetric agglomerates distribution, while the sulfated sample showed a narrow, tetramodal and asymmetric agglomerates distribution. The presence of traces of the tetragonal phase in the SO_4"-"2/ZrO_2 XRD, and the presence of SO_3 in the EDX were good indicators for future use in catalysis to provide ester. (author)

  11. MAIT application to the analysis of commercial power plants

    International Nuclear Information System (INIS)

    Goldman, L.A.; McDaniel, T.L.; Chapman, L.D.; Stack, D.

    1981-01-01

    This paper discusses a study which was conducted for the U.S. Nuclear Regulatory Commission (NRC) to determine the applicability of the Matrix Analysis of the Insider Threat (MAIT) code to the analysis of sabotage vulnerabilities of commercial power reactors. The sabotage of concern was the initiation of a release of radioactivity in excess of 10 CFR 100 guidelines. 5 refs

  12. Developing Viable Financing Models for Space Tourism

    Science.gov (United States)

    Eilingsfeld, F.; Schaetzler, D.

    2002-01-01

    Increasing commercialization of space services and the impending release of government's control of space access promise to make space ventures more attractive. Still, many investors shy away from going into the space tourism market as long as they do not feel secure that their return expectations will be met. First and foremost, attracting investors from the capital markets requires qualifying financing models. Based on earlier research on the cost of capital for space tourism, this paper gives a brief run-through of commercial, technical and financial due diligence aspects. After that, a closer look is taken at different valuation techniques as well as alternative ways of streamlining financials. Experience from earlier ventures has shown that the high cost of capital represents a significant challenge. Thus, the sophistication and professionalism of business plans and financial models needs to be very high. Special emphasis is given to the optimization of the debt-to-equity ratio over time. The different roles of equity and debt over a venture's life cycle are explained. Based on the latter, guidelines for the design of an optimized loan structure are given. These are then applied to simulating the financial performance of a typical space tourism venture over time, including the calculation of Weighted Average Cost of Capital (WACC) and Net Present Value (NPV). Based on a concluding sensitivity analysis, the lessons learned are presented. If applied properly, these will help to make space tourism economically viable.

  13. The science, development, and commercialization of postharvest biocontrol products

    Science.gov (United States)

    Postharvest biological control agents as a viable alternative to the use of synthetic chemicals have been the focus of considerable research for the last 30 years by many scientists and several commercial companies worldwide. Several antagonists of postharvest pathogens have been identified and tes...

  14. Mobile clinical decision support systems and applications: a literature and commercial review.

    Science.gov (United States)

    Martínez-Pérez, Borja; de la Torre-Díez, Isabel; López-Coronado, Miguel; Sainz-de-Abajo, Beatriz; Robles, Montserrat; García-Gómez, Juan Miguel

    2014-01-01

    The latest advances in eHealth and mHealth have propitiated the rapidly creation and expansion of mobile applications for health care. One of these types of applications are the clinical decision support systems, which nowadays are being implemented in mobile apps to facilitate the access to health care professionals in their daily clinical decisions. The aim of this paper is twofold. Firstly, to make a review of the current systems available in the literature and in commercial stores. Secondly, to analyze a sample of applications in order to obtain some conclusions and recommendations. Two reviews have been done: a literature review on Scopus, IEEE Xplore, Web of Knowledge and PubMed and a commercial review on Google play and the App Store. Five applications from each review have been selected to develop an in-depth analysis and to obtain more information about the mobile clinical decision support systems. Ninety-two relevant papers and 192 commercial apps were found. Forty-four papers were focused only on mobile clinical decision support systems. One hundred seventy-one apps were available on Google play and 21 on the App Store. The apps are designed for general medicine and 37 different specialties, with some features common in all of them despite of the different medical fields objective. The number of mobile clinical decision support applications and their inclusion in clinical practices has risen in the last years. However, developers must be careful with their interface or the easiness of use, which can impoverish the experience of the users.

  15. Technical meeting on commercial applications of nuclear analytical techniques. Meeting report

    International Nuclear Information System (INIS)

    2004-01-01

    This report summarizes the findings of the Technical Meeting on the Commercial Applications of Nuclear Analytical Techniques held in Vienna on 23-26 November 2004, where an assessment was initiated of the world capacity and market potentials for neutron activation analysis and nuclear spectroscopy, including an estimation of economic revenues. Industry and governmental agencies were identified as stakeholders for these laboratories. Examples are given of potential benefits of these techniques to the stakeholders. The potentials for commercial applications of neutron activation analysis and nuclear spectroscopy (measurement of alpha, beta and gamma ray emitting radionuclides) are addressed. First estimates are given of the worldwide capacity of these laboratories, suggestions and examples are given for potential markets and the typical organizational and technical constraints are discussed. Two case studies of commercial neutron activation analysis laboratories at a small and a medium-size reactor are given in the 'individual contributions' section of this document. An assessment of other nuclear analytical techniques such as X ray Fluorescence Spectrometry, Particle Induced X ray Emission Spectrometry or Ion Beam Analysis Spectrometry has been completed after a comprehensive collection of background information

  16. Technical meeting on commercial applications of nuclear analytical techniques. Meeting report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This report summarizes the findings of the Technical Meeting on the Commercial Applications of Nuclear Analytical Techniques held in Vienna on 23-26 November 2004, where an assessment was initiated of the world capacity and market potentials for neutron activation analysis and nuclear spectroscopy, including an estimation of economic revenues. Industry and governmental agencies were identified as stakeholders for these laboratories. Examples are given of potential benefits of these techniques to the stakeholders. The potentials for commercial applications of neutron activation analysis and nuclear spectroscopy (measurement of alpha, beta and gamma ray emitting radionuclides) are addressed. First estimates are given of the worldwide capacity of these laboratories, suggestions and examples are given for potential markets and the typical organizational and technical constraints are discussed. Two case studies of commercial neutron activation analysis laboratories at a small and a medium-size reactor are given in the 'individual contributions' section of this document. An assessment of other nuclear analytical techniques such as X ray Fluorescence Spectrometry, Particle Induced X ray Emission Spectrometry or Ion Beam Analysis Spectrometry has been completed after a comprehensive collection of background information.

  17. Development of a commercially viable piezoelectric force sensor system for static force measurement

    Science.gov (United States)

    Liu, Jun; Luo, Xinwei; Liu, Jingcheng; Li, Min; Qin, Lan

    2017-09-01

    A compensation method for measuring static force with a commercial piezoelectric force sensor is proposed to disprove the theory that piezoelectric sensors and generators can only operate under dynamic force. After studying the model of the piezoelectric force sensor measurement system, the principle of static force measurement using a piezoelectric material or piezoelectric force sensor is analyzed. Then, the distribution law of the decay time constant of the measurement system and the variation law of the measurement system’s output are studied, and a compensation method based on the time interval threshold Δ t and attenuation threshold Δ {{u}th} is proposed. By calibrating the system and considering the influences of the environment and the hardware, a suitable Δ {{u}th} value is determined, and the system’s output attenuation is compensated based on the Δ {{u}th} value to realize the measurement. Finally, a static force measurement system with a piezoelectric force sensor is developed based on the compensation method. The experimental results confirm the successful development of a simple compensation method for static force measurement with a commercial piezoelectric force sensor. In addition, it is established that, contrary to the current perception, a piezoelectric force sensor system can be used to measure static force through further calibration.

  18. The use of flow cytometry to accurately ascertain total and viable counts of Lactobacillus rhamnosus in chocolate.

    Science.gov (United States)

    Raymond, Yves; Champagne, Claude P

    2015-04-01

    The goals of this study were to evaluate the precision and accuracy of flow cytometry (FC) methodologies in the evaluation of populations of probiotic bacteria (Lactobacillus rhamnosus R0011) in two commercial dried forms, and ascertain the challenges in enumerating them in a chocolate matrix. FC analyses of total (FC(T)) and viable (FC(V)) counts in liquid or dried cultures were almost two times more precise (reproducible) than traditional direct microscopic counts (DCM) or colony forming units (CFU). With FC, it was possible to ascertain low levels of dead cells (FC(D)) in fresh cultures, which is not possible with traditional CFU and DMC methodologies. There was no interference of chocolate solids on FC counts of probiotics when inoculation was above 10(7) bacteria per g. Addition of probiotics in chocolate at 40 °C resulted in a 37% loss in viable cells. Blending of the probiotic powder into chocolate was not uniform which raised a concern that the precision of viable counts could suffer. FCT data can serve to identify the correct inoculation level of a sample, and viable counts (FCV or CFU) can subsequently be better interpreted. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  19. Potential commercial applications of centrifuge technology

    International Nuclear Information System (INIS)

    1985-08-01

    As part of an effort to prevent the loss of and maximize the use of unique developments of the centrifuge program, this document identifies and briefly describes unclassified technologies potentially available for transfer. In addition, this document presents a preliminary plan for action needed to carry out the transfer activity. Continuing efforts will provide additional descriptions of technologies which have applications that are not as apparent or as obvious as those presented here. Declassification of some of the program information, now classified as restricted data, would permit the descriptions of additional technologies which have significant commercial potential. The following are major areas of technology where transfer opportunities exist: biomedical; separation; motors and control systems; materials; vacuum; dynamics and balancing; and diagnostics and instrumentation

  20. Usage of Commercial Grade Programmable Digital Systems in Safety Related Applications

    International Nuclear Information System (INIS)

    Mandic, D.

    2006-01-01

    This paper explains methods and conditions, which if completely and correctly fulfilled, enable an operating NPP (Nuclear Power Plant) licensed and operating in accordance with the US codes and US regulatory requirements to use a commercial grade programmable digital device (PLC - Programmable Digital Controller, digital controller, digital computer or process computer) in a safety related application in a NPP. In mid 80's, when an intensive construction cycle of the new NPPs in the U.S.A. was completed, many equipment manufacturers either disappeared from the market or they abandoned their product lines that were designed and manufactured under 10 CFR Part 50 Appendix B quality assurance program. The quality assurance as defined by 10 CFR Part 50 Appendix B comprises all those planned and systematic actions necessary to provide adequate confidence that a Structure, System or Component (SSC) will perform satisfactorily in service . The operating NPPs faced the problem related to the availability of qualified equipment, components and spare parts. The US NRC (Nuclear Regulatory Commission) recognized that problem timely (Oct. 1978 revision of 10CFR21) and required a commercial grade item to be dedicated before it could be used as a basic component. A special process named Dedication of CGI - Commercial Grade Items if conducted properly, provides reasonable assurance that a commercial grade item to be used as a basic component will perform its intended safety related function and, in this respect, is deemed equivalent to an item designed and manufactured under 10 CFR Part 50 Appendix B. After that, the Dedication of CGI has been widely used mostly for relatively simple mechanical, electrical, and IandC components and spare parts. In order to provide guidance to the dedication process, EPRI has issued two documents (EPRI NP-5652 and Supplemental Guidance for EPRI NP-5652). All nuclear power plants, which comply with the US nuclear regulatory requirements, hindered as

  1. Commercial Optimization of a 100 kg/day PEM based Hydrogen Generator For Energy and Industrial Applications

    International Nuclear Information System (INIS)

    Moulthrop, L.; Anderson, E.; Chow, O.; Friedland, R.; Maloney, T.; Schiller, M.

    2006-01-01

    Commercial hydrogen generators using PEM water electrolysis are well proven, serving industrial applications worldwide in over 50 countries. Now, market and environmental requirements are converging to demand larger on-site hydrogen generators. North American liquid H 2 shortages, increasing trucking costs, developing economies with no liquid infrastructure, utilities, and forklift fuel cell fueling applications are all working to increase market demand for commercial on-site H 2 generation. These commercial applications may be satisfied by a 100 kg H 2 /day module; this platform can be the pathway towards a 500 kg H 2 /day generator desired for small fore-court hydrogen vehicle fueling stations. This paper discusses the steps necessary and activities already underway to develop a 100 to 500 kg H 2 /day PEM hydrogen generator platform to meet commercial market cost targets and approach US DoE transportation fueling cost targets. (authors)

  2. Campylobacter jejuni in commercial eggs.

    Science.gov (United States)

    Fonseca, Belchiolina Beatriz; Beletti, Marcelo Emílio; de Melo, Roberta Torres; Mendonça, Eliane Pereira; Coelho, Letícia Ríspoli; Nalevaiko, Priscila Christen; Rossi, Daise Aparecida

    2014-01-01

    This study evaluated the ability of Campylobacter jejuni to penetrate through the pores of the shells of commercial eggs and colonize the interior of these eggs, which may become a risk factor for human infection. Furthermore, this study assessed the survival and viability of the bacteria in commercial eggs. The eggs were placed in contact with wood shavings infected with C. jejuni to check the passage of the bacteria. In parallel, the bacteria were inoculated directly into the air chamber to assess the viability in the egg yolk. To determine whether the albumen and egg fertility interferes with the entry and survival of bacteria, we used varying concentrations of albumen and SPF and commercial eggs. C. jejuni was recovered in SPF eggs (fertile) after three hours in contact with contaminated wood shavings but not in infertile commercial eggs. The colonies isolated in the SPF eggs were identified by multiplex PCR and the similarity between strains verified by RAPD-PCR. The bacteria grew in different concentrations of albumen in commercial and SPF eggs. We did not find C. jejuni in commercial eggs inoculated directly into the air chamber, but the bacteria were viable during all periods tested in the wood shavings. This study shows that consumption of commercial eggs infected with C. jejuni does not represent a potential risk to human health.

  3. Guideline on evaluation and acceptance of commercial grade digital equipment for nuclear safety applications

    International Nuclear Information System (INIS)

    1996-10-01

    Nuclear power plants are increasingly upgrading their instrumentation and control (I ampersand C) systems with commercial digital equipment, which allows them to continue meeting safety and reliability requirements while controlling operating costs. However, the use of commercial software-based devices for safety related applications has raised new issues that impact design, procurement, and licensing activities. This guideline describes a consistent, comprehensive approach for the evaluation and acceptance of commercial digital equipment for nuclear safety systems

  4. Application of narrow-band television to industrial and commercial communications

    Science.gov (United States)

    Embrey, B. C., Jr.; Southworth, G. R.

    1974-01-01

    The development of narrow-band systems for use in space systems is presented. Applications of the technology to future spacecraft requirements are discussed along with narrow-band television's influence in stimulating development within the industry. The transferral of the technology into industrial and commercial communications is described. Major areas included are: (1) medicine; (2) education; (3) remote sensing for traffic control; and (5) weather observation. Applications in data processing, image enhancement, and information retrieval are provided by the combination of the TV camera and the computer.

  5. COTS low-cost 622-Mb/s free-space laser communications link for short-distance commercial applications

    Science.gov (United States)

    Morrison, Kenneth A.

    2000-05-01

    The results from a low cost 622 Mb/s, free-space laser communication link operating at 850 nm for short distance commercial applications is presented. The test results demonstrate the use of a free-space laser communications transceiver for building to building applications such as LAN, WAN and ATM operations, etc. This illustrates the potential for wide-use commercial computer network applications. The transceiver is constructed of commercial off-the-shelf materials for the development of a low-cost laser communications data link. The test system configuration utilizes standard Personal Computers with network cards and signal conversion cards for the copper to optical medical conversion. These tests precede the development of an increased data rate device operating at 2.5 Gb/s.

  6. Managing Viable Knowledge

    NARCIS (Netherlands)

    Achterbergh, J.M.I.M.; Vriens, D.J.

    2002-01-01

    In this paper, Beer's Viable System Model (VSM) is applied to knowledge management. Based on the VSM, domains of knowledge are identified that an organization should possess to maintain its viability. The logic of the VSM is also used to support the diagnosis, design and implementation of the

  7. High-energy radiation and polymers: A review of commercial processes and emerging applications

    International Nuclear Information System (INIS)

    Clough, R.L.

    2001-01-01

    Ionizing radiation has been found to be widely applicable in modifying the structure and properties of polymers, and can be used to tailor the performance of either bulk materials or surfaces. Fifty years of research in polymer radiation chemistry has led to numerous applications of commercial and economic importance, and work remains active in the application of radiation to practical uses involving polymeric materials. This paper provides a survey of radiation-processing methods of industrial interest, ranging from technologies already commercially well established, through innovations in the active R and D stage which show exceptional promise for future commercial use. Radiation-processing technologies are discussed under the following categories: cross-linking of plastics and rubbers, curing of coatings and inks, heat-shrink products, fiber-matrix composites, chain-scission for processing control, surface modification, grafting, hydrogels, sterilization, natural product enhancement, plastics recycling, ceramic precursors, electronic property materials, ion-track membranes and lithography for microdevice production. In addition to new technological innovations utilizing conventional gamma and e-beam sources, a number of promising new applications make use of novel radiation types which include ion beams (heavy ions, light ions, highly focused microscopic beams and high-intensity pulses), soft X-rays which are focused, coherent X-rays (from a synchrotron) and e-beams which undergo scattering to generate patterns

  8. Selective detection of viable seed-borne Acidovorax citrulli by real-time PCR with propidium monoazide.

    Science.gov (United States)

    Tian, Qian; Feng, Jian-Jun; Hu, Jie; Zhao, Wen-Jun

    2016-10-14

    In recent years, use of the DNA-intercalating dye propidium monoazide (PMA) in real-time PCR has been reported as a novel method to detect viable bacteria in different types of samples, such as food, environmental, and microbiological samples. In this study, viable cells of Acidovorax citrulli, the causal agent of bacterial seedling blight and fruit blotch, were selectively detected and differentiated from dead cells by real-time fluorescent polymerase chain reaction amplification after the bacterial solution was treated with the DNA-binding dye PMA. The primers and TaqMan probe were based on the A. citrulli genome (Aave_1909, Gene ID: 4669443) and were highly specific for A. citrulli. The detection threshold of this assay was 10 3 colony-forming units per mL (CFU/mL) in pure cell suspensions containing viable and dead cells and infected watermelon seeds. Application of this assay enables the selective detection of viable cells of A. citrulli and facilitates monitoring of the pathogen in watermelon and melon seeds.

  9. Axenic isolation of viable Giardia muris trophozoites.

    Science.gov (United States)

    Tillotson, K D; Buret, A; Olson, M E

    1991-06-01

    Large numbers of viable Giardia muris trophozoites were isolated from the duodenum of experimentally infected mice 6 days after inoculation with 1,000 G. muris cysts. A series of shaking, incubation, and washing steps in the presence of the broad-spectrum antibiotic piperacillin readily provided 4.9 +/- 1.5 x 10(5) G. muris trophozoites per mouse, free of detectable contaminant organisms. Anaerobic and microaerophilic culturing and scanning electron microscopy demonstrated axenic status and high purity of the isolates. The viability of trophozoites was 98 +/- 2%. Application of this technique should permit novel immunological and epidemiological analyses of G. muris infection and biochemical investigations of this protozoan parasite.

  10. Film forming microbial biopolymers for commercial applications--a review.

    Science.gov (United States)

    Vijayendra, S V N; Shamala, T R

    2014-12-01

    Microorganisms synthesize intracellular, structural and extracellular polymers also referred to as biopolymers for their function and survival. These biopolymers play specific roles as energy reserve materials, protective agents, aid in cell functioning, the establishment of symbiosis, osmotic adaptation and support the microbial genera to function, adapt, multiply and survive efficiently under changing environmental conditions. Viscosifying, gelling and film forming properties of these have been exploited for specific significant applications in food and allied industries. Intensive research activities and recent achievements in relevant and important research fields of global interest regarding film forming microbial biopolymers is the subject of this review. Microbial polymers such as pullulan, kefiran, bacterial cellulose (BC), gellan and levan are placed under the category of exopolysaccharides (EPS) and have several other functional properties including film formation, which can be used for various applications in food and allied industries. In addition to EPS, innumerable bacterial genera are found to synthesis carbon energy reserves in their cells known as polyhydroxyalkanoates (PHAs), microbial polyesters, which can be extruded into films with excellent moisture and oxygen barrier properties. Blow moldable biopolymers like PHA along with polylactic acid (PLA) synthesized chemically in vitro using lactic acid (LA), which is produced by LA bacteria through fermentation, are projected as biodegradable polymers of the future for packaging applications. Designing and creating of new property based on requirements through controlled synthesis can lead to improvement in properties of existing polysaccharides and create novel biopolymers of great commercial interest and value for wider applications. Incorporation of antimicrobials such as bacteriocins or silver and copper nanoparticles can enhance the functionality of polymer films especially in food packaging

  11. Commercial applications of large-scale Research and Development computer simulation technologies

    International Nuclear Information System (INIS)

    Kuok Mee Ling; Pascal Chen; Wen Ho Lee

    1998-01-01

    The potential commercial applications of two large-scale R and D computer simulation technologies are presented. One such technology is based on the numerical solution of the hydrodynamics equations, and is embodied in the two-dimensional Eulerian code EULE2D, which solves the hydrodynamic equations with various models for the equation of state (EOS), constitutive relations and fracture mechanics. EULE2D is an R and D code originally developed to design and analyze conventional munitions for anti-armor penetrations such as shaped charges, explosive formed projectiles, and kinetic energy rods. Simulated results agree very well with actual experiments. A commercial application presented here is the design and simulation of shaped charges for oil and gas well bore perforation. The other R and D simulation technology is based on the numerical solution of Maxwell's partial differential equations of electromagnetics in space and time, and is implemented in the three-dimensional code FDTD-SPICE, which solves Maxwell's equations in the time domain with finite-differences in the three spatial dimensions and calls SPICE for information when nonlinear active devices are involved. The FDTD method has been used in the radar cross-section modeling of military aircrafts and many other electromagnetic phenomena. The coupling of FDTD method with SPICE, a popular circuit and device simulation program, provides a powerful tool for the simulation and design of microwave and millimeter-wave circuits containing nonlinear active semiconductor devices. A commercial application of FDTD-SPICE presented here is the simulation of a two-element active antenna system. The simulation results and the experimental measurements are in excellent agreement. (Author)

  12. Current state of commercial radiation detection equipment for homeland security applications

    International Nuclear Information System (INIS)

    Klann, R.T.; Shergur, J.; Mattesich, G.

    2009-01-01

    With the creation of the U.S. Department of Homeland Security (DHS) came the increased concern that terrorist groups would attempt to manufacture and use an improvised nuclear device or radiological dispersal device. As such, a primary mission of DHS is to protect the public against the use of these devices and to assist state and local responders in finding, locating, and identifying these types of devices and materials used to manufacture these devices. This assistance from DHS to state and local responders comes in the form of grant money to procure radiation detection equipment. In addition to this grant program, DHS has supported the development of American National Standards Institute standards for radiation detection equipment and has conducted testing of commercially available instruments. This paper identifies the types and kinds of commercially available equipment that can be used to detect and identify radiological material - for use in traditional search applications as well as primary and secondary screening of personnel, vehicles, and cargo containers. In doing so, key considerations for the conduct of operations are described as well as critical features of the instruments for specific applications. The current state of commercial instruments is described for different categories of detection equipment including personal radiation detectors, radioisotope identifiers, man-portable detection equipment, and radiation portal monitors. In addition, emerging technologies are also discussed, such as spectroscopic detectors and advanced spectroscopic portal monitors

  13. CO2 electric discharge lasers - Present status and future applications

    International Nuclear Information System (INIS)

    Reilly, J.P.

    1979-01-01

    CO 2 electric discharge lasers (EDLs) have proven themselves to be efficient sources of high-power high-quality laser energy. The paper outlines applications of high-power CO 2 EDLs, applications which are now becoming commercially viable, as well as those which are still being investigated in research laboratories. Applications of CO 2 lasers are discussed relative to industrial applications (laser welding, laser surface hardening, heat treatment, and surface chemistry modification by laser alloying and laser glazing), laser radar applications, laser-induced fusion, and laser propulsion. Attention is given to requirements of applications versus status of technology. Examples are given of the engineering solutions used to address the technology issues identified by particular laser applications

  14. Enumeration of viable and non-viable larvated Ascaris eggs with quantitative PCR

    Science.gov (United States)

    Aims: The goal of the study was to further develop an incubation-qPCR method for quantifying viable Ascaris eggs. The specific objectives were to characterize the detection limit and number of template copies per egg, determine the specificity of the method, and test the method w...

  15. Viable Syntax: Rethinking Minimalist Architecture

    Directory of Open Access Journals (Sweden)

    Ken Safir

    2010-03-01

    Full Text Available Hauser et al. (2002 suggest that the human language faculty emerged as a genetic innovation in the form of what is called here a ‘keystone factor’—a single, simple, formal mental capability that, interacting with the pre-existing faculties of hominid ancestors, caused a cascade of effects resulting in the language faculty in modern humans. They take Merge to be the keystone factor, but instead it is posited here that Merge is the pre-existing mechanism of thought made viable by a principle that permits relations interpretable at the interfaces to be mapped onto c-command. The simplified minimalist architecture proposed here respects the keystone factor as closely as possible, but is justified on the basis of linguistic analyses it makes available, including a relativized intervention theory applicable across Case, scope, agreement, selection and linearization, a derivation of the A/A’-distinction from Case theory, and predictions such as why in situ wh-interpretation is island-insensitive, but susceptible to intervention effects.

  16. Application of secondary ion mass spectrometry for the characterization of commercial high performance materials

    International Nuclear Information System (INIS)

    Gritsch, M.

    2000-09-01

    The industry today offers an uncounted number of high performance materials, that have to meet highest standards. Commercial high performance materials, though often sold in large quantities, still require ongoing research and development to keep up to date with increasing needs and decreasing tolerances. Furthermore, a variety of materials is on the market that are not fully understood in their microstructure, in the way they react under application conditions, and in which mechanisms are responsible for their degradation. Secondary Ion Mass Spectrometry (SIMS) is an analytical method that is now in commercial use for over 30 years. Its main advantages are the very high detection sensitivity (down to ppb), the ability to measure all elements with isotopic sensitivity, the ability of gaining laterally resolved images, and the inherent capability of depth-profiling. These features make it an ideal tool for a wide field of applications within advanced material science. The present work gives an introduction into the principles of SIMS and shows the successful application for the characterization of commercially used high performance materials. Finally, a selected collection of my publications in reviewed journals will illustrate the state of the art in applied materials research and development with dynamic SIMS. All publications focus on the application of dynamic SIMS to analytical questions that stem from questions arising during the production and improvement of high-performance materials. (author)

  17. CASH 2021: Commercial access and space habitation

    Science.gov (United States)

    Aldrin, Andrew; Amara, Adam; Aris, Lodewijk; Baierl, Nida; Beatty, Patrick; Beaulieu, Catherine; Behnke, Torsten; Castegini, Roberta; Chauhan, Amitabh; Cojanis, Philip; Dayawansa, Pelawa; Diop, Marie; Eito, Kinya; Engle, Steve; Ferretti, Stefano; Gassama, Hamet; Genova, Bojana; Goulding, Colin; Janjua, Jameel; Jansaeng, Thidarat; Jousset, Frédéric; Kopik, Anatoly; Laurin, Catherine; Leggatt, Jason; Li, Hengnian; Mezzadri, Monica; Miura, Amane; Nolet, Simon; Ogami, Satoshi; Patry, Johanne; Patten, Laryssa; Payerne, Cyril; Peer, Guy; Prampolini, Marco; Rheaume, Caroline; Saary, Joan; Spehar, Daniela; Sufi, Atiya; Sun, Baosheng; Thompson, J. Barry; Thomson, Ward; Trautner, Roland; Tursunmuratov, Murat; Venet, Vrata; Wilems, Elizabeth; Wilson, Helen; Wittwer, Karl; Wokke, Frank; Wu, Yansheng; Zhou, Shaobin; Zilioli, Ilaria

    2002-07-01

    Issues about commercialization of space have been a growing concern in the past decade for the space community. This paper focuses on the work from a team of 51 students attending the Summer Session Program of the International Space University in Bremen, Germany. CASH 2021 (Commercial Access and Space Habitation) documents a plan that identifies commercial opportunities for space utilization that will extend human presence in space, and will chart the way forward for the next 20 years. The group selected four commercial sectors that show the most promise for the future: tourism, entertainment, space system service, assembly and debris removal, and research and development/production. The content of this document presents the results of their research. Historical activities in each of the commercial sectors are reviewed along with the current market situation. To provide a coherent background for future commercialization possibilities a scenario has been developed. This scenario includes a postulated upon ideal future and includes social, political and economic factors that may affect the space industry over the timeline of the study. The study also presents a roadmap, within the limited optimistic scenario developed, for the successful commercialization of space leading to future human presence in space. A broad range of commercially viable opportunities, not only within the current limits of the International Space Station, but also among the many new developments that are expected by 2021 are discussed.

  18. Advanced LWR technology for commercial application

    International Nuclear Information System (INIS)

    Redding, J.R.

    1993-01-01

    Advanced Light Water Reactors (ALWRs) are now being deployed and commercialized around the world. In Japan, the Tokyo Electric Power Company (TEPCO) is building the world's first ALWRs, two 1300 MWe Advanced BWRs (ABWRs). In the United States, the Department of Energy, utilities and suppliers are undertaking a cooperative program called First of a Kind Engineering (FOAKE). The purpose of FOAKE is to perform the detailed engineering of ALWRs to that they will be commercially available to U.S. utilities in the mid-1990s. The U.S. industry is in the second year of its strategic plan to have an ALWR in commercial operation by the year 2000. Elsewhere, the Taiwan Power Company has issued a Request for Proposal for two ALWRs so be built at its Lungmen site, with commercial operation of the first unit to be in the year 2000. Korea is formulating plans for an ALWR and other countries, such as Indonesia and Mexico, are looking into the feasibility of building ALWRs

  19. Neuroscience: viable applications in education?

    Science.gov (United States)

    Devonshire, Ian M; Dommett, Eleanor J

    2010-08-01

    As a relatively young science, neuroscience is still finding its feet in potential collaborations with other disciplines. One such discipline is education, with the field of neuroeducation being on the horizon since the 1960s. However, although its achievements are now growing, the partnership has not been as successful as first hopes suggested it should be. Here the authors discuss the theoretical barriers and potential solutions to this, which have been suggested previously, with particular focus on levels of research in neuroscience and their applicability to education. Moreover, they propose that these theoretical barriers are driven and maintained by practical barriers surrounding common language and research literacy. They propose that by overcoming these practical barriers through appropriate training and shared experience, neuroeducation can reach its full potential.

  20. Commercial gasifier for IGCC applications study report

    Energy Technology Data Exchange (ETDEWEB)

    Notestein, J.E.

    1990-06-01

    This was a scoping-level study to identify and characterize the design features of fixed-bed gasifiers appearing most important for a gasifier that was to be (1) potentially commercially attractive, and (2) specifically intended for us in integrated coal gasification/combined-cycle (IGCC) applications. It also performed comparative analyses on the impact or value of these design features and on performance characteristics options of the whole IGCC system since cost, efficiency, environmental traits, and operability -- on a system basis -- are what is really important. The study also reviewed and evaluated existing gasifier designs, produced a conceptual-level gasifier design, and generated a moderately advanced system configuration that was utilized as the reference framework for the comparative analyses. In addition, technical issues and knowledge gaps were defined. 70 figs., 31 tabs.

  1. A combination of direct viable count and fluorescence in situ hybridization for specific enumeration of viable Lactobacillus delbrueckii subsp.bulgaricus and Streptococcus thermophilus.

    Science.gov (United States)

    García-Hernández, J; Moreno, Y; Amorocho, C M; Hernández, M

    2012-03-01

    We have developed a direct viable count (DVC)-FISH procedure for quickly and easily discriminating between viable and nonviable cells of Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus strains, the traditional yogurt bacteria. direct viable count method has been modified and adapted for Lact. delbrueckii subsp. bulgaricus and Strep. thermophilus analysis by testing different times of incubation and concentrations of DNA-gyrase inhibitors. DVC procedure has been combined with fluorescent in situ hybridization (FISH) for the specific detection of viable cells of both bacteria with specific rRNA oligonucleotide probes (DVC-FISH). Of the four antibiotics tested (novobiocin, nalidixic acid, pipemidic acid and ciprofloxacin), novobiocin was the most effective for DVC method and the optimum incubation time was 7 h for both bacteria. The number of viable cells was obtained by the enumeration of specific hybridized cells that were elongated at least twice their original length for Lactobacillus and twice their original size for Streptococcus. This technique was successfully applied to detect viable cells in inoculated faeces. Results showed that this DVC-FISH procedure is a quick and culture-independent useful method to specifically detect viable Lact. delbrueckii subsp. bulgaricus and Strep. thermophilus in different samples, being applied for the first time to lactic acid bacteria. © 2011 The Authors. Letters in Applied Microbiology © 2011 The Society for Applied Microbiology.

  2. Commercial grade item (CGI) dedication of MDR relays for nuclear safety related applications

    Science.gov (United States)

    Das, Ranjit K.; Julka, Anil; Modi, Govind

    1994-08-01

    MDR relays manufactured by Potter & Brumfield (P&B) have been used in various safety related applications in commercial nuclear power plants. These include emergency safety features (ESF) actuation systems, emergency core cooling systems (ECCS) actuation, and reactor protection systems. The MDR relays manufactured prior to May 1990 showed signs of generic failure due to corrosion and outgassing of coil varnish. P&B has made design changes to correct these problems in relays manufactured after May 1990. However, P&B does not manufacture the relays under any 10CFR50 Appendix B quality assurance (QA) program. They manufacture the relays under their commercial QA program and supply these as commercial grade items. This necessitates CGI Dedication of these relays for use in nuclear-safety-related applications. This paper presents a CGI dedication program that has been used to dedicate the MDR relays manufactured after been used to dedicate the MDR relays manufactured after May 1990. The program is in compliance with current Nuclear Regulatory Commission (NRC) and Electric Power Research Institute (EPRI) guidelines and applicable industry standards; it specifies the critical characteristics of the relays, provides the tests and analysis required to verify the critical characteristics, the acceptance criteria for the test results, performs source verification to quality P&B for its control of the critical characteristics, and provides documentation. The program provides reasonable assurance that the new MDR relays will perform their intended safety functions.

  3. Integrated vehicle control and guidance systems in unmanned ground vehicles for commercial applications

    Science.gov (United States)

    Kenyon, Chase H.

    1995-01-01

    While there is a lot of recent development in the entire IVHS field, very few have had the opportunity to combine the many areas of development into a single integrated `intelligent' unmanned vehicle. One of our systems was developed specifically to serve a major automobile manufacturer's need for an automated vehicle chassis durability test facility. Due to the severity of the road surface human drivers could not be used. A totally automated robotic vehicle driver and guidance system was necessary. In order to deliver fixed price commercial projects now, it was apparent system and component costs were of paramount importance. Cyplex has developed a robust, cost effective single wire guidance system. This system has inherent advantages in system simplicity. Multi-signal (per vehicle lane) systems complicate path planning and layout when multiple lanes and lane changes are required, as on actual highways. The system has demonstrated high enough immunity to rain and light snow cover that normal safety reductions in speed are adequate to stay within the required system performance envelope. This system and it's antenna interface have shown the ability to guide the vehicle at slow speeds (10 MPH) with a tracking repeatability of plus or minus 1/8 of an inch. The basic guide and antenna system has been tested at speeds up to 80 mph. The system has inherently superior abilities for lane changes and precision vehicle placement. The operation of this system will be described and the impact of a system that is commercially viable now for highway and off road use will be discussed.

  4. Two applications of direct digital down converters in beam diagnostics

    International Nuclear Information System (INIS)

    Powers, Tom; Flood, Roger; Hovater, Curt; Musson, John

    2000-01-01

    The technologies of direct digital down converters, digital frequency synthesis, and digital signal processing are being used in many commercial applications. Because of this commercialization, the component costs are being reduced to the point where they are economically viable for large scale accelerator applications. This paper will discuss two applications of these technologies to beam diagnostics. In the first application the combination of direct digital frequency synthesis and direct digital down converters are coupled with digital signal processor technology in order to maintain the stable gain environment required for a multi-electrode beam position monitoring system. This is done by injecting a CW reference signal into the electronics as part of the front-end circuitry. In the second application direct digital down converters are used to provide a novel approach to the measurement of beam intensity using cavity current monitors. In this system a pair of reference signals are injected into the cavity through an auxiliary port. The beam current is then calculated as the ratio of the beam signal divided by the average of the magnitude of the two reference signals

  5. Preliminary Evaluation Of Commercial Supercapacitors For Space Applications

    Science.gov (United States)

    Gineste, Valery; Loup, Didier; Mattesco, Patrick; Neugnot, Nicolas

    2011-10-01

    Supercapacitors are identified since years as a new technology enabling energy storage together with high power delivery capability to the system. A recent ESA study [1] led by Astrium has demonstrated the interest of these devices for space application, providing that reliability and end of life performances are demonstrated. A realistic commercial on the shelf (COTS) approach (or with limited design modification approved by potential suppliers) has been favoured (as for batteries). This paper presents preliminary test results done by Astrium on COTS supercapacitors: accelerated life tests, calendar life tests, technology analyses. Based on these results, assessment and lessons learnt are drawn in view of future exhaustive supercapacitor validation and future qualification.

  6. Predictors of viable germ cell tumor in postchemotherapeutic residual retroperitoneal masses

    Directory of Open Access Journals (Sweden)

    Khalid Al Othman

    2014-01-01

    Full Text Available Objective: The aim of this study was to identify predictors of viable germ cell tumor (GCT in postchemotherapeutic residual retroperitoneal masses. Materials and Methods: The pertinent clinical and pathologic data of 16 male patients who underwent postchemotherapeutic retroperitoneal lymph node dissection (PC-RPLND at King Faisal Specialist Hospital and Research Centre between 1994 and 2005 were reviewed retrospectively. It was found that all patients received cisplatin-based chemotherapy for advanced testicular GCT. Results: Out of the 16 male patients, 2 (13%, 8 (50%, and 6 (37% had viable GCT, fibrosis, and teratoma, respectively. Ten (10 of the patients with prechemotherapeutic S1 tumor markers did not have viable GCT, and two of the six patients who had prechemotherapeutic S2 tumor markers have viable GCT. All tumor marker levels normalized after chemotherapy even in patients with viable GCT. Four patients had vascular invasion without viable GCT. Furthermore, four patients had more than 60% embryonal elements in the original pathology, but only 1 had viable GCT at PC-RPLND. Four of the five patients with immature teratoma had teratoma at PC-RPLND but no viable GCT; however, out of the four patients with mature teratoma, one had viable GCT and two had teratoma at PC-RPLND. Of the two patients with viable GCT, one had 100% embryonal cancer in the original pathology, prechemotherapeutic S2 tumor markers, history of orchiopexy, and no vascular invasion; the other patient had yolk sac tumor with 25% embryonal elements and 40% teratoma in the original pathology, and prechemotherapeutic S2 tumor markers. Conclusion: None of the clinical or pathological parameters showed a strong correlation with the presence of viable GCT in PC-RPLND. However, patients with ≥S2 may be at higher risk to have viable GCT. Further studies are needed to clarify this.

  7. Economically Viable Components from Jerusalem Artichoke (Helianthus tuberosus L.) in a Biorefinery Concept

    DEFF Research Database (Denmark)

    Johansson, Eva; Prade, Thomas; Angelidaki, Irini

    2015-01-01

    Biorefinery applications are receiving growing interest due to climatic and waste disposal issues and lack of petroleum resources. Jerusalem artichoke (Helianthus tuberosus L.) is suitable for biorefinery applications due to high biomass production and limited cultivation requirements. This paper...... focuses on the potential of Jerusalem artichoke as a biorefinery crop and the most viable products in such a case. The carbohydrates in the tubers were found to have potential for production of platform chemicals, e.g., succinic acid. However, economic analysis showed that production of platform chemicals...

  8. Marine Carotenoids: Biological Functions and Commercial Applications

    Science.gov (United States)

    Vílchez, Carlos; Forján, Eduardo; Cuaresma, María; Bédmar, Francisco; Garbayo, Inés; Vega, José M.

    2011-01-01

    Carotenoids are the most common pigments in nature and are synthesized by all photosynthetic organisms and fungi. Carotenoids are considered key molecules for life. Light capture, photosynthesis photoprotection, excess light dissipation and quenching of singlet oxygen are among key biological functions of carotenoids relevant for life on earth. Biological properties of carotenoids allow for a wide range of commercial applications. Indeed, recent interest in the carotenoids has been mainly for their nutraceutical properties. A large number of scientific studies have confirmed the benefits of carotenoids to health and their use for this purpose is growing rapidly. In addition, carotenoids have traditionally been used in food and animal feed for their color properties. Carotenoids are also known to improve consumer perception of quality; an example is the addition of carotenoids to fish feed to impart color to farmed salmon. PMID:21556162

  9. Performance measures in the earth observations commercialization applications program

    Science.gov (United States)

    Macauley, Molly K.

    1996-03-01

    Performance measures in the Earth Observations Commercialization Application Program (EOCAP) are key to its success and include net profitability; enhancements to industry productivity through generic innovations in industry practices, standards, and protocols; and documented contributions to public policy governing the newly developing remote sensing industry. Because EOCAP requires company co-funding, both parties to the agreement (the government and the corporate partner) have incentives to pursue these goals. Further strengthening progress towards these goals are requirements for business plans in the company's EOCAP proposal, detailed scrutiny given these plans during proposal selection, and regularly documented progress reports during project implementation.

  10. Commercial launch systems: A risky investment?

    Science.gov (United States)

    Dupnick, Edwin; Skratt, John

    1996-03-01

    A myriad of evolutionary paths connect the current state of government-dominated space launch operations to true commercial access to space. Every potential path requires the investment of private capital sufficient to fund the commercial venture with a perceived risk/return ratio acceptable to the investors. What is the private sector willing to invest? Does government participation reduce financial risk? How viable is a commercial launch system without government participation and support? We examine the interplay between various forms of government participation in commercial launch system development, alternative launch system designs, life cycle cost estimates, and typical industry risk aversion levels. The boundaries of this n-dimensional envelope are examined with an ECON-developed business financial model which provides for the parametric assessment and interaction of SSTO design variables (including various operational scenarios with financial variables including debt/equity assumptions, and commercial enterprise burden rates on various functions. We overlay this structure with observations from previous ECON research which characterize financial risk aversion levels for selected industrial sectors in terms of acceptable initial lump-sum investments, cumulative investments, probability of failure, payback periods, and ROI. The financial model allows the construction of parametric tradeoffs based on ranges of variables which can be said to actually encompass the ``true'' cost of operations and determine what level of ``true'' costs can be tolerated by private capitalization.

  11. Commercial applications of neutron scattering

    International Nuclear Information System (INIS)

    Hutchings, M.T.

    1993-01-01

    The fact that industry is now willing to pay the full commercial cost for certain neutron scattering experiments aimed at solving its urgent materials - related problems is a true testimony to the usefulness of neutrons as microscopic probes. This paper gives examples of such use of three techniques drawn mainly from our experience at AEA Technology Harwell Laboratory. These are diffraction to measure residual stress, small angle neutron scattering to examine hardening precipitates in ferritic steels brought about by irradiation, and reflectivity to study amorphous diamond layers deposited on silicon. In most cases it is the penetrative power of the neutron which proves to be its best asset for commercial industrial applicaitons. (author)

  12. Gas-cooled reactor commercialization study: introduction scenario and commercialization analyses for process heat applications. Final report, July 8, 1977--November 30, 1977

    International Nuclear Information System (INIS)

    1977-12-01

    This report identifies and presents an introduction scenario which can lead to the operation of High Temperature Gas Cooled Reactor demonstration plants for combined process heat and electric power generation applications, and presents a commercialization analysis relevant to the organizational and management plans which could implement a development program

  13. Gas-cooled reactor commercialization study: introduction scenario and commercialization analyses for process heat applications. Final report, July 8, 1977--November 30, 1977

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-01

    This report identifies and presents an introduction scenario which can lead to the operation of High Temperature Gas Cooled Reactor demonstration plants for combined process heat and electric power generation applications, and presents a commercialization analysis relevant to the organizational and management plans which could implement a development program.

  14. 76 FR 126 - Requirement for Commercial Users To Use Commercial Public Key Information (PKI) Certificate

    Science.gov (United States)

    2011-01-03

    ... DEPARTMENT OF DEFENSE Department of the Army Requirement for Commercial Users To Use Commercial..., SDDC will require all commercial accounts accessing transportation systems and applications to use a commercial PKI certificate or Transportation Workers Identification Credential (TWIC). This requirement will...

  15. Commercial Radio as Communication.

    Science.gov (United States)

    Rothenbuhler, Eric W.

    1996-01-01

    Compares the day-to-day work routines of commercial radio with the principles of a theoretical communication model. Illuminates peculiarities of the conduct of communication by commercial radio. Discusses the application of theoretical models to the evaluation of practicing institutions. Offers assessments of commercial radio deriving from…

  16. Deploying a Route Optimization EFB Application for Commercial Airline Operational Trials

    Science.gov (United States)

    Roscoe, David A.; Vivona, Robert A.; Woods, Sharon E.; Karr, David A.; Wing, David J.

    2016-01-01

    The Traffic Aware Planner (TAP), developed for NASA Langley Research Center to support the Traffic Aware Strategic Aircrew Requests (TASAR) project, is a flight-efficiency software application developed for an Electronic Flight Bag (EFB). Tested in two flight trials and planned for operational testing by two commercial airlines, TAP is a real-time trajectory optimization application that leverages connectivity with onboard avionics and broadband Internet sources to compute and recommend route modifications to flight crews to improve fuel and time performance. The application utilizes a wide range of data, including Automatic Dependent Surveillance Broadcast (ADS-B) traffic, Flight Management System (FMS) guidance and intent, on-board sensors, published winds and weather, and Special Use Airspace (SUA) schedules. This paper discusses the challenges of developing and deploying TAP to various EFB platforms, our solutions to some of these challenges, and lessons learned, to assist commercial software developers and hardware manufacturers in their efforts to implement and extend TAP functionality in their environments. EFB applications (such as TAP) typically access avionics data via an ARINC 834 Simple Text Avionics Protocol (STAP) server hosted by an Aircraft Interface Device (AID) or other installed hardware. While the protocol is standardized, the data sources, content, and transmission rates can vary from aircraft to aircraft. Additionally, the method of communicating with the AID may vary depending on EFB hardware and/or the availability of onboard networking services, such as Ethernet, WIFI, Bluetooth, or other mechanisms. EFBs with portable and installed components can be implemented using a variety of operating systems, and cockpits are increasingly incorporating tablet-based technologies, further expanding the number of platforms the application may need to support. Supporting multiple EFB platforms, AIDs, avionics datasets, and user interfaces presents a

  17. Modelling streamflow reductions resulting from commercial afforestation in South Africa: From research to application

    CSIR Research Space (South Africa)

    Gush, Mark B

    2006-08-01

    Full Text Available , in 1972, of legislation that required timber growers to apply for permits to establish commercial plantations. Applications to establish forestry plantations became mandatory, and were rejected if it was deemed that the afforestation would use...

  18. Trends in genetic patent applications: the commercialization of academic intellectual property.

    Science.gov (United States)

    Kers, Jannigje G; Van Burg, Elco; Stoop, Tom; Cornel, Martina C

    2014-10-01

    We studied trends in genetic patent applications in order to identify the trends in the commercialization of research findings in genetics. To define genetic patent applications, the European version (ECLA) of the International Patent Classification (IPC) codes was used. Genetic patent applications data from the PATSTAT database from 1990 until 2009 were analyzed for time trends and regional distribution. Overall, the number of patent applications has been growing. In 2009, 152 000 patent applications were submitted under the Patent Cooperation Treaty (PCT) and within the EP (European Patent) system of the European Patent Office (EPO). The number of genetic patent applications increased until a peak was reached in the year 2000, with >8000 applications, after which it declined by almost 50%. Continents show different patterns over time, with the global peak in 2000 mainly explained by the USA and Europe, while Asia shows a stable number of >1000 per year. Nine countries together account for 98.9% of the total number of genetic patent applications. In The Netherlands, 26.7% of the genetic patent applications originate from public research institutions. After the year 2000, the number of genetic patent applications dropped significantly. Academic leadership and policy as well as patent regulations seem to have an important role in the trend differences. The ongoing investment in genetic research in the past decade is not reflected by an increase of patent applications.

  19. Grazing of particle-associated bacteria-an elimination of the non-viable fraction.

    Science.gov (United States)

    Gonsalves, Maria-Judith; Fernandes, Sheryl Oliveira; Priya, Madasamy Lakshmi; LokaBharathi, Ponnapakkam Adikesavan

    Quantification of bacteria being grazed by microzooplankton is gaining importance since they serve as energy subsidies for higher trophic levels which consequently influence fish production. Hence, grazing pressure on viable and non-viable fraction of free and particle-associated bacteria in a tropical estuary controlled mainly by protist grazers was estimated using the seawater dilution technique. In vitro incubations over a period of 42h showed that at the end of 24h, growth coefficient (k) of particle-associated bacteria was 9 times higher at 0.546 than that of free forms. Further, 'k' value of viable cells on particles was double that of free forms at 0.016 and 0.007, respectively. While bacteria associated with particles were grazed (coefficient of removal (g)=0.564), the free forms were relatively less grazed indicating that particle-associated bacteria were exposed to grazers in these waters. Among the viable and non-viable forms, 'g' of non-viable fraction (particle-associated bacteria=0.615, Free=0.0086) was much greater than the viable fraction (particle-associated bacteria=0.056, Free=0.068). Thus, grazing on viable cells was relatively low in both the free and attached states. These observations suggest that non-viable forms of particle-associated bacteria were more prone to grazing and were weeded out leaving the viable cells to replenish the bacterial standing stock. Particle colonization could thus be a temporary refuge for the "persistent variants" where the viable fraction multiply and release their progeny. Copyright © 2016 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

  20. Grazing of particle-associated bacteria-an elimination of the non-viable fraction

    Directory of Open Access Journals (Sweden)

    Maria-Judith Gonsalves

    Full Text Available Abstract Quantification of bacteria being grazed by microzooplankton is gaining importance since they serve as energy subsidies for higher trophic levels which consequently influence fish production. Hence, grazing pressure on viable and non-viable fraction of free and particle-associated bacteria in a tropical estuary controlled mainly by protist grazers was estimated using the seawater dilution technique. In vitro incubations over a period of 42 h showed that at the end of 24 h, growth coefficient (k of particle-associated bacteria was 9 times higher at 0.546 than that of free forms. Further, ‘k’ value of viable cells on particles was double that of free forms at 0.016 and 0.007, respectively. While bacteria associated with particles were grazed (coefficient of removal (g = 0.564, the free forms were relatively less grazed indicating that particle-associated bacteria were exposed to grazers in these waters. Among the viable and non-viable forms, ‘g’ of non-viable fraction (particle-associated bacteria = 0.615, Free = 0.0086 was much greater than the viable fraction (particle-associated bacteria = 0.056, Free = 0.068. Thus, grazing on viable cells was relatively low in both the free and attached states. These observations suggest that non-viable forms of particle-associated bacteria were more prone to grazing and were weeded out leaving the viable cells to replenish the bacterial standing stock. Particle colonization could thus be a temporary refuge for the “persistent variants” where the viable fraction multiply and release their progeny.

  1. Time for commercializing non-food biofuel in China

    International Nuclear Information System (INIS)

    Wang, Qiang

    2011-01-01

    The booming automobile in China has added additional pressure on the country that needs to import almost 50% of its oil. Non-food-based biofuel is a viable fuel alternative for cars. China already has the required-foundation to commercialize non-food-based biofuel. Chinese crop straw and stock, energy crop, and woody biomass that could potentially be converted into energy are projected to be 700 million toe (ton of oil equivalent) in the near future. Meanwhile, Chinese food-based ethanol fuel industry ranks as the world's third after United States and Brazil. Several non-food-based ethanol plants are constructed or under constructed, one of which has been licensed. However, more efforts should be directed to commercializing non-food-based biofuel, including industrialized feedstock, strengthening key technology research, supporting private enterprise, and E10 upgrading to E20. The enormous increase in private ownership of car must compel China to commercialize biofuel. (author)

  2. Technology Implementation Plan. Fully Ceramic Microencapsulated Fuel for Commercial Light Water Reactor Application

    International Nuclear Information System (INIS)

    Snead, Lance Lewis; Terrani, Kurt A.; Powers, Jeffrey J.; Worrall, Andrew; Robb, Kevin R.; Snead, Mary A.

    2015-01-01

    This report is an overview of the implementation plan for ORNL's fully ceramic microencapsulated (FCM) light water reactor fuel. The fully ceramic microencapsulated fuel consists of tristructural isotropic (TRISO) particles embedded inside a fully dense SiC matrix and is intended for utilization in commercial light water reactor application.

  3. Technology Implementation Plan. Fully Ceramic Microencapsulated Fuel for Commercial Light Water Reactor Application

    Energy Technology Data Exchange (ETDEWEB)

    Snead, Lance Lewis [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrani, Kurt A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, Jeffrey J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Worrall, Andrew [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robb, Kevin R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Snead, Mary A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-04-01

    This report is an overview of the implementation plan for ORNL's fully ceramic microencapsulated (FCM) light water reactor fuel. The fully ceramic microencapsulated fuel consists of tristructural isotropic (TRISO) particles embedded inside a fully dense SiC matrix and is intended for utilization in commercial light water reactor application.

  4. Regulation of Viable and Optimal Cohorts

    Energy Technology Data Exchange (ETDEWEB)

    Aubin, Jean-Pierre, E-mail: aubin.jp@gmail.com [VIMADES (Viabilité, Marchés, Automatique, Décisions) (France)

    2015-10-15

    This study deals with the evolution of (scalar) attributes (resources or income in evolutionary demography or economics, position in traffic management, etc.) of a population of “mobiles” (economic agents, vehicles, etc.). The set of mobiles sharing the same attributes is regarded as an instantaneous cohort described by the number of its elements. The union of instantaneous cohorts during a mobile window between two attributes is a cohort. Given a measure defining the number of instantaneous cohorts, the accumulation of the mobile attributes on a evolving mobile window is the measure of the cohort on this temporal mobile window. Imposing accumulation constraints and departure conditions, this study is devoted to the regulation of the evolutions of the attributes which are1.viable in the sense that the accumulations constraints are satisfied at each instant;2.and, among them, optimal, in the sense that both the duration of the temporal mobile window is maximum and that the accumulation on this temporal mobile window is the largest viable one. This value is the “accumulation valuation” function. Viable and optimal evolutions under accumulation constraints are regulated by an “implicit Volterra integro-differential inclusion” built from the accumulation valuation function, solution to an Hamilton–Jacobi–Bellman partial differential equation under constraints which is constructed for this purpose.

  5. Development of Commercial Applications of a FAPY Alloy; TOPICAL

    International Nuclear Information System (INIS)

    Sikka, VK

    2001-01-01

    The Fe-16 at. (8.5 wt)% Al alloy, known as FAPY, has been identified as a superior material for heating element applications. However, while the 15-lb heats melted at the Oak Ridge National Laboratory (ORNL) could be processed into wire, the large heat melted at Hoskins Manufacturing Company (Hoskins) could not be processed under commercial processing conditions. The primary objective of the Cooperative Research and Development Agreement (CRADA) was to demonstrate that wire of the FAPY alloy could be produced under commercial conditions from air-induction-melted (AIM) heats. The specific aspects of this CRADA included: (1) Melting 15-lb heats by AIM or vacuum-induction melting (VIM) at ORNL. (2) Development of detailed processing steps including warm drawing and annealing temperature and time during cold-drawing steps. (3) Melting of 1400-lb heats at Hoskins by the Exo-Melt(trademark) process and their chemical analysis and microstructural characterization. (4) Development of tensile properties of sections of ingots from the large heats in the as-cast, hot-worked, and hot- and cold-worked conditions. (5) Microstructural characterization of cast and wrought structures and the fractured specimens. (6) Successful demonstration of processing of AIM heats at Hoskins to heating element wire. The aspects of this CRADA listed above have demonstrated that the FAPY alloy of the desired composition can be commercially produced by AIM by the use of the Exo-Melt(trademark) process. Furthermore, it also demonstrated that the wire processing steps developed for 15-lb heats at ORNL can be successfully applied to the production of wire from the large AIM heats

  6. Space Commercialization

    Science.gov (United States)

    Martin, Gary L.

    2011-01-01

    A robust and competitive commercial space sector is vital to continued progress in space. The United States is committed to encouraging and facilitating the growth of a U.S. commercial space sector that supports U.S. needs, is globally competitive, and advances U.S. leadership in the generation of new markets and innovation-driven entrepreneurship. Energize competitive domestic industries to participate in global markets and advance the development of: satellite manufacturing; satellite-based services; space launch; terrestrial applications; and increased entrepreneurship. Purchase and use commercial space capabilities and services to the maximum practical extent Actively explore the use of inventive, nontraditional arrangements for acquiring commercial space goods and services to meet United States Government requirements, including measures such as public-private partnerships, . Refrain from conducting United States Government space activities that preclude, discourage, or compete with U.S. commercial space activities. Pursue potential opportunities for transferring routine, operational space functions to the commercial space sector where beneficial and cost-effective.

  7. Quantification of viable bacteria in wastewater treatment plants by using propidium monoazide combined with quantitative PCR (PMA-qPCR).

    Science.gov (United States)

    Li, Dan; Tong, Tiezheng; Zeng, Siyu; Lin, Yiwen; Wu, Shuxu; He, Miao

    2014-02-01

    The detection of viable bacteria in wastewater treatment plants (WWTPs) is very important for public health, as WWTPs are a medium with a high potential for waterborne disease transmission. The aim of this study was to use propidium monoazide (PMA) combined with the quantitative polymerase chain reaction (PMA-qPCR) to selectively detect and quantify viable bacteria cells in full-scale WWTPs in China. PMA was added to the concentrated WWTP samples at a final concentration of 100 micromol/L and the samples were incubated in the dark for 5 min, and then lighted for 4 min prior to DNA extraction and qPCR with specific primers for Escherichia coli and Enterococci, respectively. The results showed that PMA treatment removed more than 99% of DNA from non-viable cells in all the WWTP samples, while matrices in sludge samples markedly reduced the effectiveness of PMA treatment. Compared to qPCR, PMA-qPCR results were similar and highly linearly correlated to those obtained by culture assay, indicating that DNA from non-viable cells present in WWTP samples can be eliminated by PMA treatment, and that PMA-qPCR is a reliable method for detection of viable bacteria in environmental samples. This study demonstrated that PMA-qPCR is a rapid and selective detection method for viable bacteria in WWTP samples, and that WWTPs have an obvious function in removing both viable and non-viable bacteria. The results proved that PMA-qPCR is a promising detection method that has a high potential for application as a complementary method to the standard culture-based method in the future.

  8. Characterization of the Viable but Nonculturable (VBNC State in Saccharomyces cerevisiae.

    Directory of Open Access Journals (Sweden)

    Mohammad Salma

    Full Text Available The Viable But Non Culturable (VBNC state has been thoroughly studied in bacteria. In contrast, it has received much less attention in other microorganisms. However, it has been suggested that various yeast species occurring in wine may enter in VBNC following sulfite stress.In order to provide conclusive evidences for the existence of a VBNC state in yeast, the ability of Saccharomyces cerevisiae to enter into a VBNC state by applying sulfite stress was investigated. Viable populations were monitored by flow cytometry while culturable populations were followed by plating on culture medium. Twenty-four hours after the application of the stress, the comparison between the culturable population and the viable population demonstrated the presence of viable cells that were non culturable. In addition, removal of the stress by increasing the pH of the medium at different time intervals into the VBNC state allowed the VBNC S. cerevisiae cells to "resuscitate". The similarity between the cell cycle profiles of VBNC cells and cells exiting the VBNC state together with the generation rate of cells exiting VBNC state demonstrated the absence of cellular multiplication during the exit from the VBNC state. This provides evidence of a true VBNC state. To get further insight into the molecular mechanism pertaining to the VBNC state, we studied the involvement of the SSU1 gene, encoding a sulfite pump in S. cerevisiae. The physiological behavior of wild-type S. cerevisiae was compared to those of a recombinant strain overexpressing SSU1 and null Δssu1 mutant. Our results demonstrated that the SSU1 gene is only implicated in the first stages of sulfite resistance but not per se in the VBNC phenotype. Our study clearly demonstrated the existence of an SO2-induced VBNC state in S. cerevisiae and that the stress removal allows the "resuscitation" of VBNC cells during the VBNC state.

  9. Transferring diffractive optics from research to commercial applications: Part II - size estimations for selected markets

    Science.gov (United States)

    Brunner, Robert

    2014-04-01

    In a series of two contributions, decisive business-related aspects of the current process status to transfer research results on diffractive optical elements (DOEs) into commercial solutions are discussed. In part I, the focus was on the patent landscape. Here, in part II, market estimations concerning DOEs for selected applications are presented, comprising classical spectroscopic gratings, security features on banknotes, DOEs for high-end applications, e.g., for the semiconductor manufacturing market and diffractive intra-ocular lenses. The derived market sizes are referred to the optical elements, itself, rather than to the enabled instruments. The estimated market volumes are mainly addressed to scientifically and technologically oriented optical engineers to serve as a rough classification of the commercial dimensions of DOEs in the different market segments and do not claim to be exhaustive.

  10. Commercial applications

    Science.gov (United States)

    The near term (one to five year) needs of domestic and foreign commercial suppliers of radiochemicals and radiopharmaceuticals for electromagnetically separated stable isotopes are assessed. Only isotopes purchased to make products for sale and profit are considered. Radiopharmaceuticals produced from enriched stable isotopes supplied by the Calutron facility at ORNL are used in about 600,000 medical procedures each year in the United States. A temporary or permanent disruption of the supply of stable isotopes to the domestic radiopharmaceutical industry could curtail, if not eliminate, the use of such diagnostic procedures as the thallium heart scan, the gallium cancer scan, the gallium abscess scan, and the low radiation dose thyroid scan. An alternative source of enriched stable isotopes exist in the USSR. Alternative starting materials could, in theory, eventually be developed for both the thallium and gallium scans. The development of a new technology for these purposes, however, would take at least five years and would be expensive. Hence, any disruption of the supply of enriched isotopes from ORNL and the resulting unavailability of critical nuclear medicine procedures would have a dramatic negative effect on the level of health care in the United States.

  11. SP-100 nuclear space power systems with application to space commercialization

    International Nuclear Information System (INIS)

    Smith, J.M.

    1988-01-01

    The purpose of this paper is to familiarize the Space Commercialization Community with the status and characteristics of the SP-100 space nuclear power system. The program is a joint undertaking by the Department of Defense, the Department of Energy and NASA. The goal of the program is to develop, validate, and demonstrate the technology for space nuclear power systems in the range of 10 to 1000 kWe electric for use in the future civilian and military space missions. Also discussed are mission applications which are enhanced and/or enabled by SP-100 technology and how this technology compares to that of more familiar solar power systems. The mission applications include earth orbiting platforms and lunar/Mars surface power

  12. Fuel cell power plants for automotive applications

    Science.gov (United States)

    McElroy, J. F.

    1983-02-01

    While the Solid Polymer Electrolyte (SPE) fuel cell has until recently not been considered competitive with such commercial and industrial energy systems as gas turbine generators and internal combustion engines, electrical current density improvements have markedly improved the capital cost/kW output rating performance of SPE systems. Recent studies of SPE fuel cell applicability to vehicular propulsion have indicated that with adequate development, a powerplant may be produced which will satisfy the performance, size and weight objectives required for viable electric vehicles, and that the cost for such a system would be competitive with alternative advanced power systems.

  13. Economically Viable Components from Jerusalem Artichoke (Helianthus tuberosus L.) in a Biorefinery Concept

    Science.gov (United States)

    Johansson, Eva; Prade, Thomas; Angelidaki, Irini; Svensson, Sven-Erik; Newson, William R.; Gunnarsson, Ingólfur Bragi; Persson Hovmalm, Helena

    2015-01-01

    Biorefinery applications are receiving growing interest due to climatic and waste disposal issues and lack of petroleum resources. Jerusalem artichoke (Helianthus tuberosus L.) is suitable for biorefinery applications due to high biomass production and limited cultivation requirements. This paper focuses on the potential of Jerusalem artichoke as a biorefinery crop and the most viable products in such a case. The carbohydrates in the tubers were found to have potential for production of platform chemicals, e.g., succinic acid. However, economic analysis showed that production of platform chemicals as a single product was too expensive to be competitive with petrochemically produced sugars. Therefore, production of several products from the same crop is a must. Additional products are protein based ones from tubers and leaves and biogas from residues, although both are of low value and amount. High bioactive activity was found in the young leaves of the crop, and the sesquiterpene lactones are of specific interest, as other compounds from this group have shown inhibitory effects on several human diseases. Thus, future focus should be on understanding the usefulness of small molecules, to develop methods for their extraction and purification and to further develop sustainable and viable methods for the production of platform chemicals. PMID:25913379

  14. Extended Evaluations of the Commercial Spectrometer Systems for Safeguards Applications

    Energy Technology Data Exchange (ETDEWEB)

    Duc T. Vo

    1999-08-01

    Safeguards applications require the best of the spectrometer system with excellent resolution, stability, and throughput. Instruments must perform well in all situations and environments. Data communication to the computer should be convenient, fast, and reliable. The software should have all the necessary tools and be easy to use. Portable systems should be small in size, lightweight, and have a long battery life. Nine commercially available spectrometer systems are tested with five different germanium detectors. Considering the performance of the Digital Signal Processors (DSP), digital-based spectroscope y may become the way of future gamma-ray spectroscopy.

  15. Economically viable large-scale hydrogen liquefaction

    Science.gov (United States)

    Cardella, U.; Decker, L.; Klein, H.

    2017-02-01

    The liquid hydrogen demand, particularly driven by clean energy applications, will rise in the near future. As industrial large scale liquefiers will play a major role within the hydrogen supply chain, production capacity will have to increase by a multiple of today’s typical sizes. The main goal is to reduce the total cost of ownership for these plants by increasing energy efficiency with innovative and simple process designs, optimized in capital expenditure. New concepts must ensure a manageable plant complexity and flexible operability. In the phase of process development and selection, a dimensioning of key equipment for large scale liquefiers, such as turbines and compressors as well as heat exchangers, must be performed iteratively to ensure technological feasibility and maturity. Further critical aspects related to hydrogen liquefaction, e.g. fluid properties, ortho-para hydrogen conversion, and coldbox configuration, must be analysed in detail. This paper provides an overview on the approach, challenges and preliminary results in the development of efficient as well as economically viable concepts for large-scale hydrogen liquefaction.

  16. Commercial applications of solar total energy systems. Third quarterly progress report, November 1, 1976--January 31, 1977

    Energy Technology Data Exchange (ETDEWEB)

    1977-09-01

    The application of Solar Total Energy System (STES) to the commercial sector (e.g., office buildings, shopping centers, retail stores, etc.) in the United States is investigated. Candidate solar-thermal and solar-photovoltaic concepts are considered for providing on-site electrical power generation as well as thermal energy for both heating and cooling applications. The solar-thermal concepts include the use of solar concentrators (distributed or central-receiver) for collection of the thermal energy for conversion to electricity by means of a Rankine-cycle or Brayton-cycle power-conversion system. Recoverable waste heat from the power-generation process is utilized to help meet the building thermal-energy demand. Evaluation methodology is identified to allow ranking and/or selection of the most cost-effective concept for commercial-building applications.

  17. Grain Refinement of Commercial EC Grade 1070 Aluminium Alloy for Electrical Application

    OpenAIRE

    Hassanabadi, Massoud

    2015-01-01

    The aluminium alloys for electrical conductivity applications are generally not grain refinedsince the addition of grain refiners drops the electrical conductivity by introducing impuritiesinto the melt. Non-grain refined aluminium may lead to bar fracture and cracks during themetalworking process. The present study focuses to find an optimum balance between the grain refiner addition andthe electrical conductivity of commercial EC grade 1070 aluminium alloy for electricalapplication. In orde...

  18. Asouzu's Complementary Ontology as a Foundation for a Viable ...

    African Journals Online (AJOL)

    This paper on “Asouzu's Complementary Ontology as a foundation for a viable Ethic of the Environment”, posits that an ethic of the environment can be seen as viable if it considers the whole of reality as ontologically relevant. This point of view would free environmental ethics of anthropocentric bias and its attendant ...

  19. PMA-Linked Fluorescence for Rapid Detection of Viable Bacterial Endospores

    Science.gov (United States)

    LaDuc, Myron T.; Venkateswaran, Kasthuri; Mohapatra, Bidyut

    2012-01-01

    The most common approach for assessing the abundance of viable bacterial endospores is the culture-based plating method. However, culture-based approaches are heavily biased and oftentimes incompatible with upstream sample processing strategies, which make viable cells/spores uncultivable. This shortcoming highlights the need for rapid molecular diagnostic tools to assess more accurately the abundance of viable spacecraft-associated microbiota, perhaps most importantly bacterial endospores. Propidium monoazide (PMA) has received a great deal of attention due to its ability to differentiate live, viable bacterial cells from dead ones. PMA gains access to the DNA of dead cells through compromised membranes. Once inside the cell, it intercalates and eventually covalently bonds with the double-helix structures upon photoactivation with visible light. The covalently bound DNA is significantly altered, and unavailable to downstream molecular-based manipulations and analyses. Microbiological samples can be treated with appropriate concentrations of PMA and exposed to visible light prior to undergoing total genomic DNA extraction, resulting in an extract comprised solely of DNA arising from viable cells. This ability to extract DNA selectively from living cells is extremely powerful, and bears great relevance to many microbiological arenas.

  20. On the trace-free Einstein equations as a viable alternative to general relativity

    International Nuclear Information System (INIS)

    Ellis, George F R; Van Elst, Henk; Murugan, Jeff; Uzan, Jean-Philippe

    2011-01-01

    The quantum field theoretical prediction for the vacuum energy density leads to a value for the effective cosmological constant that is incorrect by between 60 and 120 orders of magnitude. We review an old proposal of replacing Einstein's field equations by their trace-free part (the trace-free Einstein equations), together with an independent assumption of energy-momentum conservation by matter fields. While this does not solve the fundamental issue of why the cosmological constant has the value that is observed cosmologically, it is indeed a viable theory that resolves the problem of the discrepancy between the vacuum energy density and the observed value of the cosmological constant. However, one has to check that, as well as preserving the standard cosmological equations, this does not destroy other predictions, such as the junction conditions that underlie the use of standard stellar models. We confirm that no problems arise here: hence, the trace-free Einstein equations are indeed viable for cosmological and astrophysical applications. (papers)

  1. Semi-commercialization of PVP-carrageenan hydrogel

    International Nuclear Information System (INIS)

    Relleve, Lorna S.; Abad, Lucille V.; Aranilla, Charito T.; Dela Rosa, A.M.

    2008-01-01

    The Philippine Nuclear Research Institute (PNRI) has developed the PVP-Carrageenan hydrogel wound dressing by radiation processing. The PVP-Carrageenan hydrogel has undergone clinical testing for burn and bedsores. It has already a pending patent application (No. 1-2000-02471) at the Philippine Patent Office. The techno-economic feasibility study has also been completed. In order to commercialize this product, a project on semi-commercialization in partnership with the investor was proposed to Technology Incubation for Commercialization (TECHNICOM), a technology transfer program of the Department of Science and Technology (DOST). TECHNICOM was established in 2003 under the National Science and Technology Plan (2002-2020) as a strategic technology transfer program. The program aims to identify key technological breakthroughs especially those generated by R and D institutes. It can intervene through the following: technology assessment/commercial prototype development; business plan/feasibility study preparation; intellectual property rights protection; technology valuation negotiation and licensing; semi-commercial production assistance and training/consultancy services. High technology applications with commercial potentials are given priority. Under semi-commercialization stage, government funds will be provided to match private sector investment in the commercial application of a particular technology innovation. This will lessen the risk of commercialization and ensure commitment from the investors. Commercial success in the shortest time is ensured since scientist can then work closely with the private sector at the production floor while testing the gaps in the technology. (author)

  2. Commercial applications

    International Nuclear Information System (INIS)

    Anon.

    1982-01-01

    The objective of this paper is to assess the near term (one-to-five-year) needs of domestic and foreign commercial suppliers of radiochemicals and radiopharmaceuticals for electromagnetically separated stable isotopes. Only isotopes purchased to make products for sale and profit are considered in this assessment. Radiopharmaceuticals produced from enriched stable isotopes supplied by the Calutron facility at ORNL are used in about 600,000 medical procedures each year in the United States. A temporary or permanent disruption of the supply of stable isotopes to the domestic radiopharmaceutical industry could curtail, if not eliminate, the use of such diagnostic procedures as the thallium heart scan, the gallium cancer scan, the gallium abscess scan, and the low-radiation-dose thyroid scan. The word could in the preceding sentence is underlined because an alternative source of enriched stable isotopes does exist in the USSR. Alternative starting materials could, in theory, eventually be developed for both the thallium and gallium scans. The development of a new technology for these purposes, however, would take at least five years and would be expensive. Hence, any disruption of the supply of enriched isotopes from ORNL and the resulting unavailability of critical nuclear medicine procedures would have a dramatic negative effect on the level of health care in the United States

  3. A benchmark study of commercially available copper nanoparticle inks for application in organic electronic devices

    NARCIS (Netherlands)

    Polino, G.; Abbel, R.; Shanmugam, S.; Bex, G.J.P.; Hendriks, R.; Brunetti, F.; Di Carlo, A.; Andriessen, R.; Galagan, Y.

    2016-01-01

    A set of three commercial copper nanoparticle based inkjet inks has been benchmarked with respect to their potential to form conducting printed structures for future applications in organic electronic devices. Significant differences were observed in terms of jetting properties, spreading behaviour

  4. Generation of viable progeny from dead brooders of endangered catfish Clarias magur (Hamilton, 1822

    Directory of Open Access Journals (Sweden)

    Sullip Kumar Majhi

    2017-10-01

    Full Text Available The obligatory air-breathing catfish Clarias magur is a prime candidate for aquaculture owing to its unique taste, high growth rate, and hardy nature. However, recently the IUCN has listed the species under the endangered category because the population has critically declined in the wild. The sexually mature C. magur brooders are often collected from their natural habitats for seed production in captivity. In many cases, the brooder dies due to handling injuries or confinement stress. In this study, we demonstrated that viable progeny could be generated from freshly dead sexually mature C. magur. Three hours after death, the gonads were excised, macroscopically examined and gamete viability was evaluated. Artificial fertilization was performed by mixing the sperm suspension with the eggs. Water was added after 1 min of mixing to activate the fertilization process. We observed 85%-93% fertilization success from gametes derived from dead donors as opposed to 90%-95% from those derived from live control donors. The embryos showed normal development and resulted in the generation of 88%-92% viable progeny, which was similar to the progeny derived from control donors (92%-93%. The results obtained in this study will have profound implications in enhancing the seed production of endangered C. magur and could potentially be applied to other key commercially or endangered fish species. Keywords: Biological sciences, Developmental biology, Zoology

  5. Biocatalytically active silCoat-composites entrapping viable Escherichia coli.

    Science.gov (United States)

    Findeisen, A; Thum, O; Ansorge-Schumacher, M B

    2014-02-01

    Application of whole cells in industrial processes requires high catalytic activity, manageability, and viability under technical conditions, which can in principle be accomplished by appropriate immobilization. Here, we report the identification of carrier material allowing exceptionally efficient adsorptive binding of Escherichia coli whole cells hosting catalytically active carbonyl reductase from Candida parapsilosis (CPCR2). With the immobilizates, composite formation with both hydrophobic and hydrophilized silicone was achieved, yielding advanced silCoat-material and HYsilCoat-material, respectively. HYsilCoat-whole cells were viable preparations with a cell loading up to 400 mg(E. coli) · g(-1)(carrier) and considerably lower leaching than native immobilizates. SilCoat-whole cells performed particularly well in neat substrate exhibiting distinctly increased catalytic activity.

  6. Economic benefits of commercial space activities

    Science.gov (United States)

    Stone, Barbara A.

    Space is not only an endless frontier for exploration, but also a potentially rich arena for profitable commerce to benefit all mankind. Access to the unique environment of space provides opportunities for unprecedented kinds of research to develop new products and services. This research can lead to commercially viable enterprises, which will become permanent businesses, which will provide good jobs for workers, pay taxes to their governments, and return dividends to their investors. Seeking superior products and processes is vital if the economy is to grow and prosper. This paper discusses the current and potential impact on the economy of selected private sector space activities.

  7. Commercial viability of CNS drugs: balancing the risk/reward profile.

    Science.gov (United States)

    Johnson, Ginger S

    2014-01-01

    CNS has historically been a formidable therapeutic area in which to innovate owing to biological (e.g., complex neurobiology, difficulty reaching the target), as well as clinical (e.g., subjective clinical endpoints, high placebo response, lack of biomarkers) challenges. In the current market where many of the larger diseases are dominated by a generic standard of care, commercial challenges now make the triple threat of scientific-clinical-commercial risk too much for many players to tackle. However, opportunities do exist for smaller biotech companies to concentrate on narrowly focused patient populations associated with high unmet need for which risk can be tightly defined. In CNS, there are two major areas to balance the risk/reward profile and create commercially viable opportunities: To realize value, all companies (start-ups and big players) must define, measure and quantify clear and meaningful value to all stakeholders: physicians, patients, caregivers and payers. © 2013.

  8. Commercializing research: the leadership challenges for the 21st century

    International Nuclear Information System (INIS)

    Gardner, P.L.; Verma, V.

    2000-06-01

    R and D today is a large industry that consumes vast amounts of public and private funds in most countries. It is becoming increasingly evident that technology transfer and the commercialization of research done at universities and government funded research laboratories must be a key element of their comprehensive strategic plan. It involves using a verified and organized knowledge and research to develop commercially viable products. It requires a visionary leader with effective project management skills to manage and motivate a team of scientists and engineers, otherwise even a top rated researcher will enervate and wither within the walls of research laboratories. This paper will highlight the importance, challenges and techniques of commercializing technology from accelerator research laboratories. It will provide an overview of the requirements of scientific leadership for both commercialization of research and technology, together with some case studies based on the experience at TRIUMF - Canada's national sub-atomic research facility in Vancouver. TRIUMF's experience with both research and commercial developments involving innovative technologies, along with some of the important leadership and management factors that lead to successful projects will be described. (author)

  9. Commercializing research: the leadership challenges for the 21st century

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, P.L.; Verma, V

    2000-06-01

    R and D today is a large industry that consumes vast amounts of public and private funds in most countries. It is becoming increasingly evident that technology transfer and the commercialization of research done at universities and government funded research laboratories must be a key element of their comprehensive strategic plan. It involves using a verified and organized knowledge and research to develop commercially viable products. It requires a visionary leader with effective project management skills to manage and motivate a team of scientists and engineers, otherwise even a top rated researcher will enervate and wither within the walls of research laboratories. This paper will highlight the importance, challenges and techniques of commercializing technology from accelerator research laboratories. It will provide an overview of the requirements of scientific leadership for both commercialization of research and technology, together with some case studies based on the experience at TRIUMF - Canada's national sub-atomic research facility in Vancouver. TRIUMF's experience with both research and commercial developments involving innovative technologies, along with some of the important leadership and management factors that lead to successful projects will be described. (author)

  10. KrF laser cost/performance model for ICF commercial applications

    International Nuclear Information System (INIS)

    Harris, D.B.; Pendergrass, J.H.

    1985-01-01

    Simple expressions suitable for use in commercial-applications plant parameter studies for the direct capital cost plus indirect field costs and for the efficiency as a function of repetition rate were developed for pure-optical-compression KrF laser fusion drivers. These simple expressions summarize estimates obtained from detailed cost-performance studies incorporating recent results of ongoing physics, design, and cost studies. Contributions of KrF laser capital charges and D and M costs to total levelized constant-dollar (1984) unit ICF power generation cost are estimated as a function of plant size and driver pulse energy using a published gain for short-wavelength lasers and representative values of plant parameters

  11. Commercialization of terrestrial applications of aerospace power technology

    International Nuclear Information System (INIS)

    Landsberg, D.R.

    1992-01-01

    The potential for commercialization of terrestrial energy systems based upon aerospace power technology's explored. Threats to the aerospace power technology industry, caused by the end of the cold war and weak world economy are described. There are also new opportunities caused by increasing terrestrial energy needs and world-wide concern for the environment. In this paper, the strengths and weaknesses of the aerospace power industry in commercializing terrestrial energy technologies are reviewed. Finally, actions which will enable the aerospace power technology industry to commercialize products into terrestrial energy markets are described

  12. Commercial Smartphone-Based Devices and Smart Applications for Personalized Healthcare Monitoring and Management.

    Science.gov (United States)

    Vashist, Sandeep Kumar; Schneider, E Marion; Luong, John H T

    2014-08-18

    Smartphone-based devices and applications (SBDAs) with cost effectiveness and remote sensing are the most promising and effective means of delivering mobile healthcare (mHealthcare). Several SBDAs have been commercialized for the personalized monitoring and/or management of basic physiological parameters, such as blood pressure, weight, body analysis, pulse rate, electrocardiograph, blood glucose, blood glucose saturation, sleeping and physical activity. With advances in Bluetooth technology, software, cloud computing and remote sensing, SBDAs provide real-time on-site analysis and telemedicine opportunities in remote areas. This scenario is of utmost importance for developing countries, where the number of smartphone users is about 70% of 6.8 billion cell phone subscribers worldwide with limited access to basic healthcare service. The technology platform facilitates patient-doctor communication and the patients to effectively manage and keep track of their medical conditions. Besides tremendous healthcare cost savings, SBDAs are very critical for the monitoring and effective management of emerging epidemics and food contamination outbreaks. The next decade will witness pioneering advances and increasing applications of SBDAs in this exponentially growing field of mHealthcare. This article provides a critical review of commercial SBDAs that are being widely used for personalized healthcare monitoring and management.

  13. Mapping the value of commercial PV applications in the US -- Accounting for externalities

    International Nuclear Information System (INIS)

    Perez, R.; Kmiecik, M.; Herig, C.; Wenger, H.

    1999-01-01

    In previous publications, the authors reported on the geographical distribution of the economic feasibility of customer-owned commercial PV systems in the US. The results showed that several regions in the country were near or above economic breakeven. However, the authors noted that these results only reflected business as usual assumptions. They did not account for existing or prospective external value elements that could, depending on the application, considerably increase PV's feasibility threshold. In this paper, the authors look at the individual and combined impact of the following value elements: (1) Replacement Value, (2) enhanced load management value, (3) emergency value and (4) environmental value. They show that accounting for these elements could significantly increase the size of cost-effective niche markets for customer-owned commercial PV installation

  14. Industrial and commercial applications for a Triga reactor

    International Nuclear Information System (INIS)

    Green, D.

    1986-01-01

    The Physics and Radioisotope Services Group of ICI operates a Triga Reactor in support of a commercial, Industrial Radioisotope Technology Service. The technical and commercial development of this business is discussed in the context of operating a Triga Reactor in an Industrial Environment. (author)

  15. Optimization of self-consumption and techno-economic analysis of PV-battery systems in commercial applications

    International Nuclear Information System (INIS)

    Merei, Ghada; Moshövel, Janina; Magnor, Dirk; Sauer, Dirk Uwe

    2016-01-01

    Highlights: • Optimization of self-consumption and the degree of self-sufficiency in commercial applications. • Technical and economic analyses for a PV-battery system. • Sensitivity analysis considering different sizes and prices of PV and battery systems. • Investigation of batteries to increase self-consumption today is not economic in the considered applications. - Abstract: Increasing costs of electricity supply from the local grid, the decreasing photovoltaic (PV) technology costs and the decreasing PV feed-in-tariff according to the current German Renewable Energy Sources Act (EEG) will in the future raise the monetary incentives to increase the self-consumption of PV energy. This is of great interest in commercial buildings as there mostly is sufficient place to install high capacities of photovoltaic panels on their own roofs. Furthermore, the electricity purchase price from the local grid for commercial consumers nowadays is about 20 €ct/kW h, which is higher than the cost of generation of electricity from solar panels (about 8–12 €ct/kW h). Additionally, the load profiles in commercial applications have a high correlation with the generated solar energy. Hence, there is a great opportunity for economic savings. This paper presents optimization results with respect to self-consumption and degree of self-sufficiency for a supermarket in Aachen, Germany. The optimization is achieved using real measurement data of load profile and solar radiation. Besides, techno-economic analyses and sensitivity analyses have been carried out to demonstrate the influence of different PV system sizes, PV system costs and interest rates. Moreover, to raise self-consumption different battery sizes with different battery system costs have been investigated and analysed for 2015 and 2025 scenarios as well. The results show that the installation of a PV system can reduce the electricity costs through self-consumption of self-generated PV energy. Also, applying

  16. Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting The Business Operating Model and How-To Manual for 450 Specific Applications

    CERN Document Server

    Maasberg, Wolfgang

    2012-01-01

    Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting is the first proprietary manual for cleaning and rehabilitation through pressure-washing, hydro-blasting and ultra high pressure water jetting (UHP).   It examines the cleaning, restoration and rehabilitation of statuary and historical structures; manufacturing hardware; and application technologies for residential, commercial and industrial areas, structures and buildings. Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting contains over 450 applications from agricultural, marine, municipal, food processing, paper-pulp, pharmaceutical and cosmetic, industrial and power generating maintenance areas. It includes gear lists to help readers easily identify the appropriate tooling and equipment for each specific application and industry.   Commercial-Industrial Cleaning, by Pressure-Washing, Hydro-Blasting and UHP-Jetting supplies readers with the tools to create a successful business model for re...

  17. Commercialization of fuel-cells

    Energy Technology Data Exchange (ETDEWEB)

    Penner, S.S.; Appleby, A.J.; Baker, B.S.; Bates, J.L.; Buss, L.B.; Dollard, W.J.; Farris, P.J.; Gillis, E.A.; Gunsher, J.A.; Khandkar, A.; Krumpelt, M.; O' Sullivan, J.B.; Runte, G.; Savinell, R.F.; Selman, J.R.; Shores, D.A.; Tarman, P.

    1995-03-01

    This report is an abbreviated version of the ''Report of the DOE Advanced Fuel Cell Commercialization Working Group (AFC2WG),'' released January 1995. We describe fuel-cell commercialization for stationary power applications of phosphoric acid, molten carbonate, solid oxide, and polymer electrolyte membrane fuel cells.

  18. Distributed photovoltaic generation in Brazil: An economic viability analysis of small-scale photovoltaic systems in the residential and commercial sectors

    International Nuclear Information System (INIS)

    Holdermann, Claudius; Kissel, Johannes; Beigel, Jürgen

    2014-01-01

    This paper examines the economic viability of small-scale, grid-connected photovoltaics in the Brazilian residential and commercial sectors after the introduction of the net metering regulation in April 2012. This study uses the discounted cash flow method to calculate the specific investment costs that are necessary for photovoltaic systems to be economically viable for each of the 63 distribution networks in Brazil. We compare these values to the system costs that are estimated in the comprehensive study on photovoltaics that was developed by the Brazilian Association of Electric and Electronic Industries (ABINEE). In our calculation, we utilize the current electricity tariffs, including fees and taxes, which we obtained through telephone interviews and publicly available information. We obtained a second important parameter by simulating PV-systems with the program PV ⁎ Sol at the distribution company headquarters' locations. In our base case scenario that reflects the current situation, in none of the distribution networks photovoltaics is economically viable in either the commercial or residential sectors. We improved the environment for grid-connected photovoltaics in our scenarios by assuming both lower PV-system costs and a lower discount rate to determine the effect on photovoltaics viability. - Highlights: • We calculate the economic viability of photovoltaics in the residential and commercial sectors in Brazil. • The PV ⁎ Sol simulations are carried out at the headquarter locations for the 63 distribution companies. • Currently in none of the distribution networks, photovoltaics is economically viable in either the commercial or residential sectors. • We analyze how the variation of the specific investment costs and of the discount rate affects the economic viability

  19. Coke gasification costs, economics, and commercial applications

    International Nuclear Information System (INIS)

    Jahnke, F.C.; Falsetti, J.S.; Wilson, R.F.

    1996-01-01

    The disposition of petroleum coke remains a problem for modern high conversion refineries. Market uncertainty and the price for coke can prevent the implementation of otherwise attractive projects. The commercially proven Texaco Gasification Process remains an excellent option for clean, cost effective coke disposition as demonstrated by the new coke gasification units coming on-line and under design. Previous papers, have discussed the coke market and general economics of coke gasification. This paper updates the current market situation and economics, and provide more details on cost and performance based on recent studies for commercial plants

  20. Microalgae bulk growth model with application to industrial scale systems

    NARCIS (Netherlands)

    Quinn, J.; Winter, de L.; Bradley, T.

    2011-01-01

    The scalability of microalgae growth systems is a primary research topic in anticipation of the commercialization of microalgae-based biofuels. To date, there is little published data on the productivity of microalgae in growth systems that are scalable to commercially viable footprints. To inform

  1. Commercial Smartphone-Based Devices and Smart Applications for Personalized Healthcare Monitoring and Management

    Directory of Open Access Journals (Sweden)

    Sandeep Kumar Vashist

    2014-08-01

    Full Text Available Smartphone-based devices and applications (SBDAs with cost effectiveness and remote sensing are the most promising and effective means of delivering mobile healthcare (mHealthcare. Several SBDAs have been commercialized for the personalized monitoring and/or management of basic physiological parameters, such as blood pressure, weight, body analysis, pulse rate, electrocardiograph, blood glucose, blood glucose saturation, sleeping and physical activity. With advances in Bluetooth technology, software, cloud computing and remote sensing, SBDAs provide real-time on-site analysis and telemedicine opportunities in remote areas. This scenario is of utmost importance for developing countries, where the number of smartphone users is about 70% of 6.8 billion cell phone subscribers worldwide with limited access to basic healthcare service. The technology platform facilitates patient-doctor communication and the patients to effectively manage and keep track of their medical conditions. Besides tremendous healthcare cost savings, SBDAs are very critical for the monitoring and effective management of emerging epidemics and food contamination outbreaks. The next decade will witness pioneering advances and increasing applications of SBDAs in this exponentially growing field of mHealthcare. This article provides a critical review of commercial SBDAs that are being widely used for personalized healthcare monitoring and management.

  2. Computers for Manned Space Applications Base on Commercial Off-the-Shelf Components

    Science.gov (United States)

    Vogel, T.; Gronowski, M.

    2009-05-01

    Similar to the consumer markets there has been an ever increasing demand in processing power, signal processing capabilities and memory space also for computers used for science data processing in space. An important driver of this development have been the payload developers for the International Space Station, requesting high-speed data acquisition and fast control loops in increasingly complex systems. Current experiments now even perform video processing and compression with their payload controllers. Nowadays the requirements for a space qualified computer are often far beyond the capabilities of, for example, the classic SPARC architecture that is found in ERC32 or LEON CPUs. An increase in performance usually demands costly and power consuming application specific solutions. Continuous developments over the last few years have now led to an alternative approach that is based on complete electronics modules manufactured for commercial and industrial customers. Computer modules used in industrial environments with a high demand for reliability under harsh environmental conditions like chemical reactors, electrical power plants or on manufacturing lines are entered into a selection procedure. Promising candidates then undergo a detailed characterisation process developed by Astrium Space Transportation. After thorough analysis and some modifications, these modules can replace fully qualified custom built electronics in specific, although not safety critical applications in manned space. This paper focuses on the benefits of COTS1 based electronics modules and the necessary analyses and modifications for their utilisation in manned space applications on the ISS. Some considerations regarding overall systems architecture will also be included. Furthermore this paper will also pinpoint issues that render such modules unsuitable for specific tasks, and justify the reasons. Finally, the conclusion of this paper will advocate the implementation of COTS based

  3. Design and Development of a 100 MVA HTS Generator for Commercial Entry

    Energy Technology Data Exchange (ETDEWEB)

    None

    2007-06-07

    In 2002, General Electric and the US Department of Energy (DOE) entered into a cooperative agreement for the development of a commercialized 100 MVA generator using high temperature superconductors (HTS) in the field winding. The intent of the program was to: (1) identify and develop technologies that would be needed for such a generator; (2) develop conceptual designs for generators with ratings of 100 MVA and higher using HTS technology; (3) perform proof of concept tests at the 1.5 MW level for GE's proprietary warm iron rotor HTS generator concept; and (4) design, build, and test a prototype of a commercially viable 100 MVA generator that could be placed on the power grid. This report summarizes work performed during the program and is provided as one of the final program deliverables. The design for the HTS generator was based on GE's warm iron rotor concept in which a cold HTS coil is wound around a warm magnetic iron pole. This approach for rotating HTS electrical machinery provides the efficiency benefits of the HTS technology while addressing the two most important considerations for power generators in utility applications: cost and reliability. The warm iron rotor concept uses the least amount of expensive HTS wire compared to competing concepts and builds on the very high reliability of conventional iron core stators and armature windings.

  4. Coal liquefaction becomes viable

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-11-15

    In 2003 the May/June issue of CoalTrans International speculated that coal liquefaction would become viable due to falling coal prices. This has not proved the case but the sustained high oil price is sparking new interest. A survey by Energy Intelligence and Marketing Research during November 2005 revealed a growth in the number of projects under development or at the feasibility stage. The article reports projects in China, the USA, Australia, New Zealand, the Philippines and India. China is commissioning the first wave of large liquefaction plants. The key question is whether other countries, particularly the USA, will follow.

  5. Development of ZIF-8 membranes: opportunities and challenges for commercial applications

    KAUST Repository

    Lai, Zhiping

    2018-03-24

    Metal organic framework (MOF) membranes have attracted significant attentions in recent years because of their potentials in gas and liquid separations and other applications such as catalysis and chemical sensors, etc. More than half of the MOF membrane publications up to date are related to ZIF-8 system, because of its easy synthesis, relatively high stability, and excellent gas separation performance, which allows many novel ideas to be easily implemented. Extensive studies have shown that ZIF-8 membranes hold great potentials in gas separations, but may face great challenges in liquid separations mainly because of their poor stability. This is also a common observation for other MOF membranes. As such, in this article we use ZIF-8 membrane as a prototype and focus on its development in gas separations for the discussions of the most concerned issues related to membrane commercialization including membrane synthesis, separation performance, stability, process reproducibility, and finally on the opportunities and challenges that MOF membranes may face in industrial applications.

  6. Development of ZIF-8 membranes: opportunities and challenges for commercial applications

    KAUST Repository

    Lai, Zhiping

    2018-01-01

    Metal organic framework (MOF) membranes have attracted significant attentions in recent years because of their potentials in gas and liquid separations and other applications such as catalysis and chemical sensors, etc. More than half of the MOF membrane publications up to date are related to ZIF-8 system, because of its easy synthesis, relatively high stability, and excellent gas separation performance, which allows many novel ideas to be easily implemented. Extensive studies have shown that ZIF-8 membranes hold great potentials in gas separations, but may face great challenges in liquid separations mainly because of their poor stability. This is also a common observation for other MOF membranes. As such, in this article we use ZIF-8 membrane as a prototype and focus on its development in gas separations for the discussions of the most concerned issues related to membrane commercialization including membrane synthesis, separation performance, stability, process reproducibility, and finally on the opportunities and challenges that MOF membranes may face in industrial applications.

  7. An application of commercial data averaging techniques in pulsed photothermal experiments

    International Nuclear Information System (INIS)

    Grozescu, I.V.; Moksin, M.M.; Wahab, Z.A.; Yunus, W.M.M.

    1997-01-01

    We present an application of data averaging technique commonly implemented in many commercial digital oscilloscopes or waveform digitizers. The technique was used for transient data averaging in the pulsed photothermal radiometry experiments. Photothermal signals are surrounded by an important amount of noise which affect the precision of the measurements. The effect of the noise level on photothermal signal parameters in our particular case, fitted decay time, is shown. The results of the analysis can be used in choosing the most effective averaging technique and estimating the averaging parameter values. This would help to reduce the data acquisition time while improving the signal-to-noise ratio

  8. Strengthening Agricultural Research Capacity for Viable Extension ...

    African Journals Online (AJOL)

    Strengthening Agricultural Research Capacity for Viable Extension Policies in Nigeria: An Exploration of Ricoeur's Hermeneutic Theory for Analysing Extension Research. ... Progressively more, researchers use hermeneutic philosophy to inform the conduct of interpretive research. Analogy between the philosophical ...

  9. Compositional characteristics of commercial yoghurt based on quantitative determination of viable lactic acid bacteria

    Directory of Open Access Journals (Sweden)

    Niketić Gordana B.

    2009-01-01

    Full Text Available Yoghurt quality is particularly difficult to standardize because of the many forms, varieties, manufacturing methods, ingredients and consumer preferences that exist. Since these factors will always play an important role, it is unlikely that a uniform yoghurt quality concept will ever emerge, such as has been developed for other dairy products. There are a number of common denominators, however that have bearing on yoghurt quality. Since a number of producers are recognized within the broad category entitled yoghurt. This situation makes yoghurt an interesting, challenging, but also a confusing area to work in. The present investigation was undertaken to isolate from commercial yoghurt the strains involved in its manufacture and determine the characteristics of Streptococcus thermophilus and Lactobacillus delbrueckii subsp.bulgaricus. This study is concerned with the lactic acid bacteria (L.delbrueckii subsp. bulgaricus and S. thermophilus growth in yoghurt from involving different procedures and with the determination of the number of lactic acid bacteria in dependence of the temperature and acidity in the period of storage. Predominant samples of yoghurt were with 11-107/ml lactic acid lactococci (44.28%.

  10. Tokamaks with high-performance resistive magnets: advanced test reactors and prospects for commercial applications

    International Nuclear Information System (INIS)

    Bromberg, L.; Cohn, D.R.; Williams, J.E.C.; Becker, H.; Leclaire, R.; Yang, T.

    1981-10-01

    Scoping studies have been made of tokamak reactors with high performance resistive magnets which maximize advantages gained from high field operation and reduced shielding requirements, and minimize resistive power requirements. High field operation can provide very high values of fusion power density and n tau/sub e/ while the resistive power losses can be kept relatively small. Relatively high values of Q' = Fusion Power/Magnet Resistive Power can be obtained. The use of high field also facilitates operation in the DD-DT advanced fuel mode. The general engineering and operational features of machines with high performance magnets are discussed. Illustrative parameters are given for advanced test reactors and for possible commercial reactors. Commercial applications that are discussed are the production of fissile fuel, electricity generation with and without fissioning blankets and synthetic fuel production

  11. A Rapid Method for Quantifying Viable Mycobacterium avium subsp. paratuberculosis in Cellular Infection Assays

    Science.gov (United States)

    Pooley, Hannah B.; de Silva, Kumudika; Purdie, Auriol C.; Begg, Douglas J.; Whittington, Richard J.

    2016-01-01

    ABSTRACT Determining the viability of bacteria is a key outcome of in vitro cellular infection assays. Currently, this is done by culture, which is problematic for fastidious slow-growing bacteria such as Mycobacterium avium subsp. paratuberculosis, where it can take up to 4 months to confirm growth. This study aimed to identify an assay that can rapidly quantify the number of viable M. avium subsp. paratuberculosis cells in a cellular sample. Three commercially available bacterial viability assays along with a modified liquid culture method coupled with high-throughput quantitative PCR growth detection were assessed. Criteria for assessment included the ability of each assay to differentiate live and dead M. avium subsp. paratuberculosis organisms and their accuracy at low bacterial concentrations. Using the culture-based method, M. avium subsp. paratuberculosis growth was reliably detected and quantified within 2 weeks. There was a strong linear association between the 2-week growth rate and the initial inoculum concentration. The number of viable M. avium subsp. paratuberculosis cells in an unknown sample was quantified based on the growth rate, by using growth standards. In contrast, none of the commercially available viability assays were suitable for use with samples from in vitro cellular infection assays. IMPORTANCE Rapid quantification of the viability of Mycobacterium avium subsp. paratuberculosis in samples from in vitro cellular infection assays is important, as it allows these assays to be carried out on a large scale. In vitro cellular infection assays can function as a preliminary screening tool, for vaccine development or antimicrobial screening, and also to extend findings derived from experimental animal trials. Currently, by using culture, it takes up to 4 months to obtain quantifiable results regarding M. avium subsp. paratuberculosis viability after an in vitro infection assay; however, with the quantitative PCR and liquid culture method

  12. Commercialization in Innovation Management

    DEFF Research Database (Denmark)

    Sløk-Madsen, Stefan Kirkegaard; Ritter, Thomas; Sornn-Friese, Henrik

    For any firm, the ultimate purpose of new product development is the commercialization of the new offerings. Despite its regular use in the product innovation and general management science literature, commercialization is only loosely defined and applied. This lack of conceptual clarity about...... the processes at the interface between product development and customer application is noteworthy as it hinders the theoretical development of the field. In this paper, we explore how research has advanced our understanding of commercialization in product innovation over a 30 year period by mapping different...

  13. Large-scale commercial applications of the in situ vitrification remediation technology

    International Nuclear Information System (INIS)

    Campbell, B.E.; Hansen, J.E.; McElroy, J.L.; Thompson, L.E.; Timmerman, C.L.

    1994-01-01

    The first large-scale commercial application of the innovative In Situ Vitrification (ISV) remediation technology was completed at the Parsons Chemical/ETM Enterprises Superfund site in Michigan State midyear 1994. This project involved treating 4,800 tons of pesticide and mercury-contaminated soil. The project also involved performance of the USEPA SITE Program demonstration test for the ISV technology. The Parsons project involved consolidation and staging of contaminated soil from widespread locations on and nearby the site. This paper presents a brief description of the ISV technology along with case-study type information on these two sites and the performance of the ISV technology on them. The paper also reviews other remediation projects where ISV has been identified as the/a preferred remedy, and where ISV is currently planned for use. These sites include soils contaminated with pesticides, dioxin, PCP, paint wastes, and a variety of heavy metals. This review of additional sites also includes a description of a planned radioactive mixed waste remediation project in Australia that contains large amounts of plutonium, uranium, lead, beryllium, and metallic and other debris buried in limestone and dolomitic soil burial pits. Initial test work has been completed on this application, and preparations are now underway for pilot testing in Australia. This project will demonstrate the applicability of the ISV technology to the challenging application of buried mixed wastes

  14. Center for commercial applications of combustion in space (CCACS); A partnership for space commercialization at the Colorado School of Mines

    Science.gov (United States)

    Schowengerdt, F. D.; Kee, Bob; Linne, Mark; McKinnon, Tom; Moore, John; Parker, Terry; Readey, Dennis; Tilton, John E.; Helble, Joe

    1997-01-01

    The Center for Commercial Applications of Combustion in Space (CCACS) is a NASA/Industry/University consortium at the Colorado School of Mines (CSM). The mission of the Center is to assist industry in developing commercial products by conducting combustion research which takes advantage of the unique properties of space. By conducting experiments in near-zero gravity, convection and buoyancy effects can be minimized and new fundamental design-related knowledge can be gained which can be used to improve combustion-related products and processes on earth. Companies, government laboratories and universities most actively involved in CCACS at present include ABB Combustion, ADA Technologies, Advanced Refractory Technologies, Golden Technologies, Lockheed-Martin, Southwest Sciences, Space Systems/Lora, NASA-Lewis, JPL, the Baylor Dental School and the University of Connecticut. Products and processes of interest to the Center participants include industrial process combustors; catalytic combustion; Halon replacements; ceramic powders, whiskers and fibers; metal-matrix composites; NiTi for bone replacement; diamond coatings for oil-well drill bits; zeolites; imaging sensor arrays and other instrumentation for flame and particulate diagnostics. The center also assists member companies in marketing the resulting products and processes.

  15. Bioactivity evaluation of commercial calcium phosphate-based bioceramics for bone regeneration

    Energy Technology Data Exchange (ETDEWEB)

    Borrós, S.; Mas, A.

    2016-11-01

    Calcium phosphate-based bioceramics constitute a great promise for bone tissue engineering as they chemically resemble to mammalian bone and teeth. Their use is a viable alternative for bone regeneration as it avoids the use of autografts and allografts, which usually involves immunogenic reactions and patient’s discomfort. This work evolves around the study of the bioactivity potential of different commercially available bone substitutes based in calcium phosphate through the characterization of their ionic exchangeability when immersed in simulated body fluid (SBF). (Author)

  16. Investigation of Removal Capacities of Biofilters for Airborne Viable Micro-Organisms

    Science.gov (United States)

    Soret, Rémi; Fanlo, Jean-Louis; Malhautier, Luc; Geiger, Philippe; Bayle, Sandrine

    2018-01-01

    New emerging issues appears regarding the possible aerosolization of micro-organisms from biofilters to the ambient air. Traditional bioaerosol sampling and cultural methods used in literature offer relative efficiencies. In this study, a new method revolving around a particle counter capable of detecting total and viable particles in real time was used. This counter (BioTrak 9510-BD) uses laser-induced fluorescence (LIF) technology to determine the biological nature of the particle. The concentration of viable particles was measured on two semi-industrial pilot scale biofilters in order to estimate the Removal Efficiency in viable particles (REvp) in stable conditions and to examine the influence of pollutant feeding and relative humidification of the gaseous effluent on the REvp. The REvp of biofilters reached near 80% and highlighted both the stability of that removal and the statistical equivalence between two identical biofilters. Pollutant deprivation periods of 12 h, 48 h and 30 days were shown to have no influence on the biofilters’ removal capacity, demonstrating the robustness and adaptation capacities of the flora. In contrast, a 90-day famine period turned the biofilters into emitters of viable particles. Finally, the humidification of the effluent was shown to negatively influence the removal capacity for viable particles, as drying off the air was shown to increase the REvp from 60 to 85%. PMID:29562709

  17. Cost reductions of fuel cells for transport applications: fuel processing options

    Energy Technology Data Exchange (ETDEWEB)

    Teagan, W P; Bentley, J; Barnett, B [Arthur D. Little, Inc., Cambridge, MA (United States)

    1998-03-15

    The highly favorable efficiency/environmental characteristics of fuel cell technologies have now been verified by virtue of recent and ongoing field experience. The key issue regarding the timing and extent of fuel cell commercialization is the ability to reduce costs to acceptable levels in both stationary and transport applications. It is increasingly recognized that the fuel processing subsystem can have a major impact on overall system costs, particularly as ongoing R and D efforts result in reduction of the basic cost structure of stacks which currently dominate system costs. The fuel processing subsystem for polymer electrolyte membrane fuel cell (PEMFC) technology, which is the focus of transport applications, includes the reformer, shift reactors, and means for CO reduction. In addition to low cost, transport applications require a fuel processor that is compact and can start rapidly. This paper describes the impact of factors such as fuel choice operating temperature, material selection, catalyst requirements, and controls on the cost of fuel processing systems. There are fuel processor technology paths which manufacturing cost analyses indicate are consistent with fuel processor subsystem costs of under $150/kW in stationary applications and $30/kW in transport applications. As such, the costs of mature fuel processing subsystem technologies should be consistent with their use in commercially viable fuel cell systems in both application categories. (orig.)

  18. Proteolytic and ACE-inhibitory activities of probiotic yogurt containing non-viable bacteria as affected by different levels of fat, inulin and starter culture

    OpenAIRE

    Shakerian, Mansour; Razavi, Seyed Hadi; Ziai, Seyed Ali; Khodaiyan, Faramarz; Yarmand, Mohammad Saeid; Moayedi, Ali

    2013-01-01

    In this study, the effects of fat (0.5 %, 3.2 % and 5.0 %), inulin (0.0 and 1.0 %) and starter culture (0.0 %, 0.5 %, 1.0 % and 1.5 %) on the angiotensin converting enzyme (ACE)-inhibitory activity of probiotic yogurt containing non-viable bacteria were assessed. Proteolytic activities of bacteria were also investigated. Yogurts were prepared either using a sole yogurt commercial culture including Streptococcus thermophilus and Lactobacillus delbrueckii subs. bulgaricus or bifidobacterium ani...

  19. Modular Platform for Commercial Mobile Robots

    DEFF Research Database (Denmark)

    Kjærgaard, Morten

    , and not on putting the robots on the commercial market. At the time when this research project was started in May 2010, the amount of successful commercial applications based on mobile robots was very limited. The most known applications were vacuum cleaners, lawn mowers, and few examples of specialized transport...... by the individual groups and perhaps a few close industrial partners. This research project addresses the problem of increasing the potential for more commercial applications based on mobile wheeled robots. Therefore the main focus is not on inventing new ground-breaking robotics technology, but instead...... period, a signicant research community was created around one specific robot control framework called ROS. From the very beginning,this research project acknowledged the value of such a community, and put a significant eort into in uencing the ROS framework to become usable also for industry...

  20. Commercial and industrial applications of color ink jet: a technological perspective

    Science.gov (United States)

    Dunand, Alain

    1996-03-01

    In just 5 years, color ink-jet has become the dominant technology for printing color images and graphics in the office and home markets. In commercial printing, the traditional printing processes are being influenced by new digital techniques. Color ink-jet proofing, and concepts such as computer to film/plate or digital processes are contributing to the evolution of the industry. In industrial color printing, the penetration of digital techniques is just beginning. All widely used conventional contact printing technologies involve mechanical printing forms including plates, screens or engraved cylinders. Such forms, which need to be newly created and set up for each job, increase costs. In our era of fast changing customer demands, growing needs for customization, and increasing use of digital exchange of information, the commercial and industrial printing markets represent an enormous potential for digital printing technologies. The adoption characteristics for the use of color ink-jet in these industries are discussed. Examples of color ink-jet applications in the fields of billboard printing, floor/wall covering decoration, and textile printing are described. The requirements on print quality, productivity, reliability, substrate compatibility, and color lead to the consideration of various types of ink-jet technologies. Key technical enabling factors and directions for future improvements are presented.

  1. In situ vitrification: Demonstrated capabilities and potential applications

    International Nuclear Information System (INIS)

    Luey, J.K.

    1993-01-01

    A large-scale demonstration of the in situ vitrification (ISV) process was performed in April 1990 on the 116-B-6A Crib in the 100 Area of the Hanford Site in southeastern Washington. The 116-B-6A Crib is a radioactive mixed waste site and was selected to demonstrate the applicability of ISV to soils contaminated with mixed wastes common to many US Department of Energy (DOE) sites. Results from the demonstration show that the ISV process is a viable remediation technology for contaminated soils. The demonstration of the ISV process on an actual contaminated soil site followed research and development efforts by the Pacific Northwest Laboratory (PNL) over the last 10 years. PNL's research has led to the development of the ISV process as a viable remediation technology for contaminated soils and the creation of a commercial supplier of ISV services, Geosafe Corporation. Development efforts for ISV applications other than treatment of contaminated soils, by PNL and in collaboration with Oak Ridge National Laboratory (ORNL) and Idaho National Engineering Laboratory (INEL), show the ISV process has potential applicability for remediating buried waste sites, remediating underground storage tanks, and enabling the placement of subsurface vitrified barriers and engineered structures. This paper discusses the results from the April 1990 large-scale demonstration and provides a general overview of the current capabilities of the ISV process for contaminated soils. In addition, this paper outlines some of the technical issues associated with other ISV applications and provides a qualitative discussion of the level of effort needed to resolve these technical issues

  2. Intersatellite Link (ISL) application to commercial communications satellites. Volume 1: Executive summary

    Science.gov (United States)

    Young, S. Lee

    1987-01-01

    Based on a comprehensive evaluation of the fundamental Intersatellite Link (ISL) systems characteristics, potential applications of ISLs to domestic, regional, and global commercial satellite communications were identified, and their cost-effectiveness and other systems benefits quantified wherever possible. Implementation scenarios for the cost-effective communications satellite systems employing ISLs were developed for the first launch in 1993 to 1994 and widespread use of ISLs in the early 2000's. Critical technology requirements for both the microwave (60 GHz) and optical (0.85 micron) ISL implementations were identified, and their technology development programs, including schedule and cost estimates, were derived.

  3. Spatiotemporal Dynamics of Total Viable Vibrio spp. in a NW Mediterranean Coastal Area.

    Science.gov (United States)

    Girard, Léa; Peuchet, Sébastien; Servais, Pierre; Henry, Annabelle; Charni-Ben-Tabassi, Nadine; Baudart, Julia

    2017-09-27

    A cellular approach combining Direct Viable Counting and Fluorescent In Situ Hybridization using a one-step multiple-probe technique and Solid Phase Cytometry (DVC-FISH-SPC) was developed to monitor total viable vibrios and cover the detection of a large diversity of vibrios. FISH combined three probes in the same assay and targeted sequences located at different positions on the 16S rRNA of Vibrio and Aliivibrio members. We performed a 10-month in situ study to investigate the weekly dynamics of viable vibrios relative to culturable counts at two northwestern Mediterranean coastal sites, and identified the key physicochemical factors for their occurrence in water using a multivariate analysis. Total viable and culturable cell counts showed the same temporal pattern during the warmer season, whereas the ratios between both methods were inverted during the colder seasons (<15°C), indicating that some of the vibrio community had entered into a viable but non-culturable (VBNC) state. We confirmed that Seawater Surface Temperature explained 51-62% of the total variance in culturable counts, and also showed that the occurrence of viable vibrios is controlled by two variables, pheopigment (15%) and phosphate (12%) concentrations, suggesting that other unidentified factors play a role in maintaining viability.

  4. Droplet digital PCR improves absolute quantification of viable lactic acid bacteria in faecal samples.

    Science.gov (United States)

    Gobert, Guillaume; Cotillard, Aurélie; Fourmestraux, Candice; Pruvost, Laurence; Miguet, Jean; Boyer, Mickaël

    2018-03-14

    Analysing correlations between the observed health effects of ingested probiotics and their survival in digestive tract allows adapting their preparations for food. Tracking ingested probiotic in faecal samples requires accurate and specific tools to quantify live vs dead cells at strain level. Traditional culture-based methods are simpler to use but they do not allow quantifying viable but non-cultivable (VBNC) cells and they are poorly discriminant below the species level. We have set up a viable PCR (vPCR) assay combining propidium monoazide (PMA) treatment and either real time quantitative PCR (qPCR) or droplet digital PCR (ddPCR) to quantify a Lactobacillus rhamnosus and two Lactobacillus paracasei subsp. paracasei strains in piglet faeces. Adjustments of the PMA treatment conditions and reduction of the faecal sample size were necessary to obtain accurate discrimination between dead and live cells. The study also revealed differences of PMA efficiency among the two L. paracasei strains. Both PCR methods were able to specifically quantify each strain and provided comparable total bacterial counts. However, quantification of lower numbers of viable cells was best achieved with ddPCR, which was characterized by a reduced lower limit of quantification (improvement of up to 1.76 log 10 compared to qPCR). All three strains were able to survive in the piglets' gut with viability losses between 0.78 and 1.59 log 10 /g faeces. This study shows the applicability of PMA-ddPCR to specific quantification of small numbers of viable bacterial cells in the presence of an important background of unwanted microorganisms, and without the need to set up standard curves. It also illustrates the need to adapt PMA protocols according to the final matrix and target strain, even for closely related strains. The PMA-ddPCR approach provides a new tool to quantify bacterial survival in faecal samples from a preclinical and clinical trial. Copyright © 2018 The Authors. Published by

  5. 9 CFR 113.26 - Detection of viable bacteria and fungi except in live vaccine.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Detection of viable bacteria and fungi... VECTORS STANDARD REQUIREMENTS Standard Procedures § 113.26 Detection of viable bacteria and fungi except... required to be free of viable bacteria and fungi, they shall also be tested as prescribed in this section...

  6. Commercialization of nuclear power plant decommissioning technology

    International Nuclear Information System (INIS)

    Williams, D.H.

    1983-01-01

    The commercialization of nuclear power plant decommissioning is presented as a step in the commercialization of nuclear energy. Opportunities for technology application advances are identified. Utility planning needs are presented

  7. Can Malin's gravitational-field equations be modified to obtain a viable theory of gravity to obtain a viable theory of gravity to obtain a viable theory of gravity

    International Nuclear Information System (INIS)

    Smalley, L.L.; Prestage, J.

    1976-01-01

    Malin's gravitational theory, which was recently shown by Lindblom and Nester to be incorrect, is modified by means of a recently proposed method for obtaining viable gravitational theories. The resulting self-consistent theory, which is in effect a Rastall-type modification of the Einstein theory, exhibits nonconservation of momentum, yet agrees with all experimental limits known to date within the PPN framework

  8. Monotone viable trajectories for functional differential inclusions

    Science.gov (United States)

    Haddad, Georges

    This paper is a study on functional differential inclusions with memory which represent the multivalued version of retarded functional differential equations. The main result gives a necessary and sufficient equations. The main result gives a necessary and sufficient condition ensuring the existence of viable trajectories; that means trajectories remaining in a given nonempty closed convex set defined by given constraints the system must satisfy to be viable. Some motivations for this paper can be found in control theory where F( t, φ) = { f( t, φ, u)} uɛU is the set of possible velocities of the system at time t, depending on the past history represented by the function φ and on a control u ranging over a set U of controls. Other motivations can be found in planning procedures in microeconomics and in biological evolutions where problems with memory do effectively appear in a multivalued version. All these models require viability constraints represented by a closed convex set.

  9. Technology leadership: a road map to commercially viable PEMFC stack technology. Paper no. IGEC-1-008

    International Nuclear Information System (INIS)

    Stone, C.

    2005-01-01

    'Full text:' In February 2005, Ballard announced its most recent advances in PEMFC stack technology. This technology development exhibited, we believe, for the first time the capability of a single PEMFC stack design to demonstrate combined excellence in cost reduction, freeze start capability from -20 C and durability under an automotive OEM defined dynamic operating cycle, comparable to that experienced by a fuel cell stack in an actual vehicle. One month later, building on the above technology leadership demonstration, Ballard announced a technology ' oad map' that defined a path to commercially viability for a PEMFC stack by 2010. The key target parameters for cost reduction, durability, freeze start and stack power density are described in detail along with demonstrated historical capability and a clear path as to how Ballard will achieve the required targets. (author)

  10. The commercial potential of Nova Scotian natural gas

    International Nuclear Information System (INIS)

    Power, M.; Jewkes, E.

    1992-01-01

    The Scotian Shelf has estimated potential natural gas reserves of 18 trillion ft 3 . A project cash flow analysis of the development and production from Nova Scotia's discovered natural gas pools is presented to determine the commercial potential of these resources. The modelling framework proposed by Power and Jewkes (1990) is used in the analysis. This framework consists of three sub-models: a drilling model, a pool-cost model, and a filtration model. The model was run 84 times, once for each combination of the 21 price levels and 4 discount rates used in the study. It was assumed that exploration and delineation drilling, project construction, and operation were completed in 35 years. The sensitivity of commercial declarations to the discount rate is most clearly seen in the measure of commercially recoverable volumes calculated by the model. Gas prices below $1.80 per thousand ft 3 (MCF) do not result in any of the significant discoveries being declared as commercially viable. As prices rise above this level, a 6% discount rate results in the largest of the discovered pools being assessed as commercial. When prices have risen sufficiently to offset the discount rate effect, the differences in commercial declarations fall progressively as prices continue to rise. The financial variables (profit and fiscal take) both exhibit increasing sensitivity to the discount rate. The results suggest a limited role for Scotian Shelf gas in Canada's energy future. Landed prices must be in the range of $2.80-$4.00/MCF before sufficient quantities of gas are made available. It is likely that the market for such gas will be small and limited primarily to an interfuel substitution role. 16 refs., 4 figs., 3 tabs

  11. A ternary phase-field model incorporating commercial CALPHAD software and its application to precipitation in superalloys

    International Nuclear Information System (INIS)

    Wen, Y.H.; Lill, J.V.; Chen, S.L.; Simmons, J.P.

    2010-01-01

    A ternary phase-field model was developed that is linked directly to commercial CALPHAD software to provide quantitative thermodynamic driving forces. A recently available diffusion mobility database for ordered phases is also implemented to give a better description of the diffusion behavior in alloys. Because the targeted application of this model is the study of precipitation in Ni-based superalloys, a Ni-Al-Cr model alloy was constructed. A detailed description of this model is given in the paper. We have considered the misfit effects of the partitioning of the two solute elements. Transformation rules of the dual representation of the γ+γ ' microstructure by CALPHAD and by the phase field are established and the link with commercial CALPHAD software is described. Proof-of-concept tests were performed to evaluate the model and the results demonstrate that the model can qualitatively reproduce observed γ ' precipitation behavior. Uphill diffusion of Al is observed in a few diffusion couples, showing the significant influence of Cr on the chemical potential of Al. Possible applications of this model are discussed.

  12. Commercial application of laser fusion

    International Nuclear Information System (INIS)

    Booth, L.A.

    1976-01-01

    The fundamentals of laser-induced fusion, some laser-fusion reactor concepts, and attendant means of utilizing the thermonuclear energy for commercial electric power generation are discussed. Theoretical fusion-pellet microexplosion energy release characteristics are described and the effects of pellet design options on pellet-microexplosion characteristics are discussed. The results of analyses to assess the engineering feasibility of reactor cavities for which protection of cavity components is provided either by suitable ablative materials or by diversion of plasmas by magnetic fields are presented. Two conceptual laser-fusion electric generating stations, based on different laser-fusion reactor concepts, are described

  13. A spreadsheet-based microcomputer application for determining cost-effectiveness of commercial lighting retrofit opportunities

    International Nuclear Information System (INIS)

    Spain, T.K.

    1992-01-01

    Lighting accounts for 20-25% of electricity use in the United States. With estimates of 50-70% potential reductions being made by energy engineers, lighting is a promising area for cost-effective energy conservation projects in commercial buildings. With an extensive array of alternatives available to replace or modify existing lighting systems, simple but effective calculation tools are needed to help energy auditors evaluate lighting retrofits. This paper describes a spreadsheet-based microcomputer application for determining the cost-effectiveness of commercial lighting retrofits. Developed to support walk-through energy audits conducted by the Industrial Energy Advisory Service (IdEAS), the spreadsheet provides essential comparative data for evaluating the payback of alternatives. The impact of alternatives on environmental emissions is calculated to help communicate external costs and sell the project, if appropriate. The methodology and calculations are fully documented to allow the user to duplicate the spreadsheet and modify it as needed

  14. Small-wind-systems application analysis. Technical report and executive summary

    Science.gov (United States)

    1981-06-01

    A small wind energy conversion systems (SWECS) analysis was conducted to estimate the potential market for SWEC, or wind machines smaller than 100 kW for five selected applications. The goals were to aid manufacturers in attaining financing by convincing venture capital investors of the potential of SWECS and to aid government planners in allocating R and D expenditures that will effectively advance SWECS commercialization. Based on these goals, the study: (1) provides a basis for assisting the DOE in planning R and D programs that will advance the state of SWECS industry; (2) quantifies estimates of market size vs. installed system cost to enable industry to plan expansion of capacity and product lines; (3) identifies marketing strategies for industry to use in attaining financing from investors and in achieving sales goals; and (4) provides DOE with data that will assist in determining actions, incentives, and/or legislation required to achieve a commercially viable SWECS industry. The five applications were selected through an initial screening and priority-ranking analysis. The year of analysis was 1985, but all dollar amounts, such as fuel costs, are expressed in 1980 dollars. The five SWECS applications investigated were farm residences, non-farm residences, rural electric cooperatives, feed grinders, and remote communities.

  15. Viable Techniques, Leontief’s Closed Model, and Sraffa’s Subsistence Economies

    Directory of Open Access Journals (Sweden)

    Alberto Benítez

    2014-11-01

    Full Text Available This paper studies the production techniques employed in economies that reproduce themselves. Special attention is paid to the distinction usually made between those that do not produce a surplus and those that do, which are referred to as first and second class economies, respectively. Based on this, we present a new definition of viable economies and show that every viable economy of the second class can be represented as a viable economy of the first class under two different forms, Leontief‘s closed model and Sraffa’s subsistence economies. This allows us to present some remarks concerning the economic interpretation of the two models. On the one hand, we argue that the participation of each good in the production of every good can be considered as a normal characteristic of the first model and, on the other hand, we provide a justification for the same condition to be considered a characteristic of the second model. Furthermore, we discuss three definitions of viable techniques advanced by other authors and show that they differ from ours because they admit economies that do not reproduce themselves completely.

  16. Can surveillance systems identify and avert adverse drug events? A prospective evaluation of a commercial application.

    Science.gov (United States)

    Jha, Ashish K; Laguette, Julia; Seger, Andrew; Bates, David W

    2008-01-01

    Computerized monitors can effectively detect and potentially prevent adverse drug events (ADEs). Most monitors have been developed in large academic hospitals and are not readily usable in other settings. We assessed the ability of a commercial program to identify and prevent ADEs in a community hospital. and Measurement We prospectively evaluated the commercial application in a community-based hospital. We examined the frequency and types of alerts produced, how often they were associated with ADEs and potential ADEs, and the potential financial impact of monitoring for ADEs. Among 2,407 patients screened, the application generated 516 high priority alerts. We were able to review 266 alerts at the time they were generated and among these, 30 (11.3%) were considered substantially important to warrant contacting the physician caring for the patient. These 30 alerts were associated with 4 ADEs and 11 potential ADEs. In all 15 cases, the responsible physician was unaware of the event, leading to a change in clinical care in 14 cases. Overall, 23% of high priority alerts were associated with an ADE (95% confidence interval [CI] 12% to 34%) and another 15% were associated with a potential ADE (95% CI 6% to 24%). Active surveillance used approximately 1.5 hours of pharmacist time daily. A commercially available, computer-based ADE detection tool was effective at identifying ADEs. When used as part of an active surveillance program, it can have an impact on preventing or ameliorating ADEs.

  17. Using Pesticides: Commercial Applicator Manual, Texas. Agricultural Pest Control - Field Crop Pest Control, Fruit and Vegetable Pest Control, Weed and Brush Control.

    Science.gov (United States)

    Texas A and M Univ., College Station. Texas Agricultural Extension Service.

    This document is designed to provide commercial pesticide applicators with practical information and regulations required by the Texas Department of Agriculture. The manual includes two major sections. The first section discusses labels and labeling, pesticides, aerial application, ground application, pesticide safety, pests and pest damage,…

  18. Commercial NAA — Is It a Success? Evaluation of a Twenty Year Experiment

    International Nuclear Information System (INIS)

    Parry, S.

    2013-01-01

    The commercial service at Imperial College was maintained for twenty years by juggling staff, equipment and irradiation facilities, building when required and downsizing when necessary. At no point was the service entirely self-sufficient since staff had more than one role and participated in teaching and research as well as the analytical service. The balance was of benefit everyone concerned, including students who have studied with us and gained experience of working within a well maintained and quality assured laboratory. The benefits of collaborating with industry cannot be overestimated, with the secondary effects for research and teaching identified previously. A key change took place in the early 2000s, which can be seen in Figure 5 by the fall in income from 2002. The author’s academic department became a separate cost centre to the Reactor Centre, and irradiations were charged at a more realistic price. Once the true costs were built in, including space, overheads and irradiation charges, it was not possible to maintain a viable business plan without reducing staff to a non-viable number. As a result, in 2003 the analytical service was handed to the Reactor Centre, in which the business could remain viable because the irradiation charge became income not expenditure. Without the continued interactions that academic research generated, the NAA service has diminished with very few customers in the past few years. Staff are occupied with internal work for the reactor such as routine monitoring using gamma spectrometry. In summary the introduction and operation of a commercial service is to be recommended, particularly in those situations where it can complement other parts of the organisation such other analytical or academic activities. It is not practical to fund reactor operations entirely on commercial activities, but it can result in a number of spin-offs that can increase other income streams such as teaching and research projects. Over the past 28

  19. Commercial speech in crisis: Crisis Pregnancy Center regulations and definitions of commercial speech.

    Science.gov (United States)

    Gilbert, Kathryn E

    2013-02-01

    Recent attempts to regulate Crisis Pregnancy Centers, pseudoclinics that surreptitiously aim to dissuade pregnant women from choosing abortion, have confronted the thorny problem of how to define commercial speech. The Supreme Court has offered three potential answers to this definitional quandary. This Note uses the Crisis Pregnancy Center cases to demonstrate that courts should use one of these solutions, the factor-based approach of Bolger v. Youngs Drugs Products Corp., to define commercial speech in the Crisis Pregnancy Center cases and elsewhere. In principle and in application, the Bolger factor-based approach succeeds in structuring commercial speech analysis at the margins of the doctrine.

  20. Technology leadership: a road map to commercially viable PEMFC stack technology. Paper no. IGEC-1-008

    Energy Technology Data Exchange (ETDEWEB)

    Stone, C. [Ballard Power Systems, Burnaby, British Columbia (Canada)

    2005-07-01

    'Full text:' In February 2005, Ballard announced its most recent advances in PEMFC stack technology. This technology development exhibited, we believe, for the first time the capability of a single PEMFC stack design to demonstrate combined excellence in cost reduction, freeze start capability from -20 C and durability under an automotive OEM defined dynamic operating cycle, comparable to that experienced by a fuel cell stack in an actual vehicle. One month later, building on the above technology leadership demonstration, Ballard announced a technology {sup '}oad map' that defined a path to commercially viability for a PEMFC stack by 2010. The key target parameters for cost reduction, durability, freeze start and stack power density are described in detail along with demonstrated historical capability and a clear path as to how Ballard will achieve the required targets. (author)

  1. Technology data characterizing refrigeration in commercial buildings: Application to end-use forecasting with COMMEND 4.0

    Energy Technology Data Exchange (ETDEWEB)

    Sezgen, O.; Koomey, J.G.

    1995-12-01

    In the United States, energy consumption is increasing most rapidly in the commercial sector. Consequently, the commercial sector is becoming an increasingly important target for state and federal energy policies and also for utility-sponsored demand side management (DSM) programs. The rapid growth in commercial-sector energy consumption also makes it important for analysts working on energy policy and DSM issues to have access to energy end-use forecasting models that include more detailed representations of energy-using technologies in the commercial sector. These new forecasting models disaggregate energy consumption not only by fuel type, end use, and building type, but also by specific technology. The disaggregation of the refrigeration end use in terms of specific technologies, however, is complicated by several factors. First, the number of configurations of refrigeration cases and systems is quite large. Also, energy use is a complex function of the refrigeration-case properties and the refrigeration-system properties. The Electric Power Research Institute`s (EPRI`s) Commercial End-Use Planning System (COMMEND 4.0) and the associated data development presented in this report attempt to address the above complications and create a consistent forecasting framework. Expanding end-use forecasting models so that they address individual technology options requires characterization of the present floorstock in terms of service requirements, energy technologies used, and cost-efficiency attributes of the energy technologies that consumers may choose for new buildings and retrofits. This report describes the process by which we collected refrigeration technology data. The data were generated for COMMEND 4.0 but are also generally applicable to other end-use forecasting frameworks for the commercial sector.

  2. Range of Applicability and Bias Determination for Postclosure Criticality of Commercial Spent Nuclear Fuel

    International Nuclear Information System (INIS)

    Radulescu, Georgeta; Mueller, Don; Goluoglu, Sedat; Hollenbach, Daniel F; Fox, Patricia B

    2007-01-01

    The purpose of this calculation report, Range of Applicability and Bias Determination for Postclosure Criticality of Commercial Spent Nuclear Fuel, is to validate the computational method used to perform postclosure criticality calculations. The validation process applies the criticality analysis methodology approach documented in Section 3.5 of the Disposal Criticality Analysis Methodology Topical Report. The application systems for this validation consist of waste packages containing transport, aging, and disposal canisters (TAD) loaded with commercial spent nuclear fuel (CSNF) of varying assembly types, initial enrichments, and burnup values that are expected from the waste stream and of varying degree of internal component degradation that may occur over the 10,000-year regulatory time period. The criticality computational tool being evaluated is the general-purpose Monte Carlo N-Particle (MCNP) transport code. The nuclear cross-section data distributed with MCNP 5.1.40 and used to model the various physical processes are based primarily on the Evaluated Nuclear Data File/B Version VI (ENDF/B-VI) library. Criticality calculation bias and bias uncertainty and lower bound tolerance limit (LBTL) functions for CSNF waste packages are determined based on the guidance in ANSI/ANS 8.1-1998 (Ref. 4) and ANSI/ANS 8.17-2004 (Ref. 5), as described in Section 3.5.3 of Ref. 1. The development of this report is consistent with Test Plan for: Range of Applicability and Bias Determination for Postclosure Criticality. This calculation report has been developed in support of licensing activities for the proposed repository at Yucca Mountain, Nevada, and the results of the calculation may be used in the criticality evaluation for CSNF waste packages based on a conceptual TAD canister.

  3. Requirements for a commercial-scale domestic Mo-99 supply

    International Nuclear Information System (INIS)

    Coats, R.

    2009-01-01

    This presentation describes the requirements for commercial-scale domestic Molybdenum-99 supply for the United States. It outlines the USA demand for Molybdenum-99 and the supply situation in the USA. Domestic supply ceased in the late 80s. The basic supply issues for USA are quantity, product quality, process control and logistics. It is proposed that the most viable solution to the chronic radionuclide supply problem faced by the USA medical community is the development of a domestic and dedicated single-purpose LEU- based reactor, collocated with a separation processing facility, and capable supplying 100-200% of U.S. demand for the principle clinical radionuclide, Molybdenum-99.

  4. Methodology for validating technical tools to assess customer Demand Response: Application to a commercial customer

    International Nuclear Information System (INIS)

    Alcazar-Ortega, Manuel; Escriva-Escriva, Guillermo; Segura-Heras, Isidoro

    2011-01-01

    The authors present a methodology, which is demonstrated with some applications to the commercial sector, in order to validate a Demand Response (DR) evaluation method previously developed and applied to a wide range of industrial and commercial segments, whose flexibility was evaluated by modeling. DR is playing a more and more important role in the framework of electricity systems management for the effective integration of other distributed energy resources. Consequently, customers must identify what they are using the energy for in order to use their flexible loads for management purposes. Modeling tools are used to predict the impact of flexibility on the behavior of customers, but this result needs to be validated since both customers and grid operators have to be confident in these flexibility predictions. An easy-to-use two-steps method to achieve this goal is presented in this paper.

  5. Commercial incineration demonstration

    International Nuclear Information System (INIS)

    Vavruska, J.S.; Borduin, L.C.

    1982-01-01

    Low-level radioactive wastes (LLW) generated by nuclear utilities presently are shipped to commercial burial grounds for disposal. Increasing transportation and disposal costs have caused industry to consider incineration as a cost-effective means of volume reduction of combustible LLW. Repeated inquiries from the nuclear industry regarding the applicability of the Los Alamos controlled air incineration (CAI) design led the DOE to initiate a commercial demonstration program in FY-1980. Development studies and results in support of this program involving ion exchange resin incineration and fission/activation product distributions within the Los Alamos CAI are described

  6. 40 CFR 171.7 - Submission and approval of State plans for certification of commercial and private applicators of...

    Science.gov (United States)

    2010-07-01

    ... authorities are pending enactment and/or promulgation, the Governor (or Chief Executive) may request that a...) Any changes in commercial applicator subcategories. (iii) A summary of enforcement activities related... contents of examinations (e.g., multiple choice, true-false) and submission of sample examination questions...

  7. Commercial Applications of X Ray Spectrometric Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Wegrzynek, D., E-mail: D.Wedgrznek@iaea.org [International Atomic Energy Agency, The IAEA Laboratories, Seibersdorf, Vienna (Austria)

    2013-07-15

    In the 21st century, the X-ray fluorescence (XRF) technique is widely used in process control, industrial applications and for routine elemental analysis. The technique has a multielement capability capable of detecting elements with Z {>=} 10, with a few instruments capable of detecting also elements with Z {>=} 5. It is characterized by a non-destructive analysis process and relatively good detection limits, typically one part per million, for a wide range of elements. The first commercial XRF instruments were introduced to the market about 50 years ago. They were the wavelength dispersive X ray fluorescence (WDXRF) spectrometers utilizing Bragg's law and reflection on crystal lattices for sequential elemental analysis of sample composition. The advances made in radiation detector technology, especially the introduction of semiconductor detectors, improvements in signal processing electronics, availability and exponential growth of personal computer market led to invention of energy dispersive X ray fluorescence (EDXRF) technique. The EDXRF is more cost effective as compared to WDXRF. It also allows for designing compact instruments. Such instruments can be easily tailored to the needs of different customers, integrated with industrial installations, and also miniaturized for the purpose of in-situ applications. The versatility of the technique has been confirmed in a spectacular way by using the XRF and X-ray spectrometric techniques, among few others, during the NASA and ESA missions in search for the evidence of life and presence of water on the surface of Mars. The XRF technique has achieved its strong position within the atomic spectroscopy group of analytical techniques not only due to its versatility but also due to relatively low running costs, as compared to the commonly used methods, e.g., atomic absorption spectrometry (AAS) or inductively coupled plasma atomic emission/mass spectrometry (ICP-AES/MS). Presently, the XRF technique together with X ray

  8. Evaluations of the commercial spectrometer systems for safeguards applications using the germanium detectors

    International Nuclear Information System (INIS)

    Vo, D.T.

    1998-01-01

    Safeguards applications require the best spectrometer systems with excellent resolution, stability, and throughput. Instruments must perform well in all the situations and environments. Data communication to the computer should be convenient, fast, and reliable. The software should have all the necessary tools and be ease to use. Portable systems should be small in size, lightweight, and have a long battery life. Nine commercially available spectrometer systems are tested with both the planar and coaxial germanium detectors. Considering the performance of the Digital Signal Processors (DSP), digital-based spectroscopy may be the future of gamma-ray spectroscopy

  9. Commercialization of an S-band standing-wave electron accelerator for industrial applications

    Science.gov (United States)

    Moon, Jin-Hyeok; Kwak, Gyeong-Il; Han, Jae-Ik; Lee, Gyu-Baek; Jeon, Seong-Hwan; Kim, Jae-Young; Hwang, Cheol-Bin; Lee, Gi-Yong; Kim, Young-Man; Park, Sung-Ju

    2016-09-01

    An electron accelerator system has been developed for use in industrial, as well as possible medical, applications. Based on our experiences achieved during prototype system development and various electron beam acceleration tests, we have built a stable and compact system for sales purposes. We have integrated a self-developed accelerating cavity, an E-gun pulse driver, a radio-frequency (RF) power system, a vacuum system, a cooling system, etc. into a frame with a size of 1800 × 1000 × 1500 mm3. The accelerating structure is a side-coupled standing-wave type operating in the π/2 mode (tuned to~3 GHz). The RF power is provided by using a magnetron driven by a solid-state modulator. The electron gun is a triode type with a dispenser cathode (diameter of 11 mm). The system is capable of delivering a maximum 900-W average electron beam power with tight focusing at the target. Until now, we have performed various electron beam tests and X-ray beam tests after having built the system, have completed the beam assessment for commercializations, and have been preparing full-fledged sales activity. This article reports on our system development processes and on some of our early test results for commercializations.

  10. Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology.

    Science.gov (United States)

    Pentek, Tyler; Newenhouse, Eric; O'Brien, Brennin; Chauhan, Abhay Singh

    2017-01-14

    Resveratrol (RSV) is well known for its anti-oxidant and anti-aging properties. However, resveratrol is insoluble in water and has stability issues. Recently, efforts were placed to prepare a resveratrol-based advanced anti-aging topical product but it contains harsh organic solvents and oils that could be harmful to the human body and the environment. Hence, we propose the use of a multifunctional dendrimer to solve the solubility and stability issues of resveratrol. A dendrimer-resveratrol complex was prepared, optimized and tested for solubility enhancement, stability in solution and cream dosage forms. We have also developed a high performance liquid chromatography method to measure the resveratrol within the final product. PAMAM dendrimers increased the solubility and stability of resveratrol in water and semisolid dosage forms. Therefore, this product would be water based 'green' formulation devoid of harsh organic solvents and oils and can be safely applied to the skin. Additionally, we have shown that the dendrimer helped to increase overall RSV loading and skin penetration of resveratrol. The dendrimer-RSV formulation was successfully scaled up towards commercialization. Dendrimer with RSV has led to an innovation in anti-aging cream and solutions that could be commercially marketed. Dendrimer-RSV complex could also be added to other product forms for additional purposes and applications.

  11. A Statistical Analysis of the Economic Drivers of Battery Energy Storage in Commercial Buildings: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Long, Matthew; Simpkins, Travis; Cutler, Dylan; Anderson, Katie

    2016-11-01

    There is significant interest in using battery energy storage systems (BESS) to reduce peak demand charges, and therefore the life cycle cost of electricity, in commercial buildings. This paper explores the drivers of economic viability of BESS in commercial buildings through statistical analysis. A sample population of buildings was generated, a techno-economic optimization model was used to size and dispatch the BESS, and the resulting optimal BESS sizes were analyzed for relevant predictor variables. Explanatory regression analyses were used to demonstrate that peak demand charges are the most significant predictor of an economically viable battery, and that the shape of the load profile is the most significant predictor of the size of the battery.

  12. Modification of polysaccharides: Pharmaceutical and tissue engineering applications with commercial utility (patents)

    Energy Technology Data Exchange (ETDEWEB)

    Malviya, Rishabha, E-mail: rishabhamalviya19@gmail.com [Polymer Science Laboratory, Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greator Noida, UP (India); Department of Pharmacy, Uttarkhand Technical University, Dehradun, Uttarkhand (India); Sharma, Pramod Kumar [Polymer Science Laboratory, Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Greator Noida, UP (India); Dubey, Susheel Kumar [Siddarth Institute of Pharmacy, Dehradun, Uttarkhand (India)

    2016-11-01

    Polymer modifications open new era for the development of polymers with requisite properties. Use of modified polymers is practically boundless. Different studies focus on biomedical applications of chemically modified polysaccharides. Development and utilization of modified polysaccharides get attention to be used as carrier for pharmaceutical drug delivery as well as tissue engineering scaffolds. Grafted polymer shows better cellular regeneration, signal transmission, diagnostic and imaging material than putative form. This review article aims to discuss various approaches to modify naturally derived polymer and their applications as pharmaceutical drug carrier and as a material for wound dressing and artificial cartilage due to better biophysical cues. Manuscript included various patents based on the applications of modified polymers and techniques used to modify polymers. - Highlights: • Properties of natural polysaccharides can be modulated by modification in their basic backbone. • Polysaccharides can be easily modified using microwave irradiation as compared to conventional closed vessel modification. • Biodegradable and biocompatible nature of modified polymer promotes their use in targeted cellular delivery of pharmaceuticals. • Studies show strong support that biodegradable polymers have ability to modulate cell signaling, cellular attachment, migration, proliferation and differentiation. • Manuscript reveals the fact that various commercial patents have been granted for the use of modified polymer.

  13. APPLICATION OF FORMS AND METHODS OF COMMERCIALIZATION OF INNOVATIONS THROUGH THE INTERACTION OF UNIVERSITIES AND ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Svetlana E. Sitnikova

    2018-03-01

    Full Text Available In the conditions of formation of economy based on knowledge, a key condition for successful development is the effective integration of science, education and business. Currently, the commercialization of innovation becomes a necessary factor for sustainable development of universities, one of their main tools to increase its competitiveness in the market of educational services and products. The efficiency of the process of innovation commercialization is conditioned by the rational choice of forms and methods of implementing this process. The interaction of universities and enterprises in the innovative clusters provides benefits such as effective dissemination of information about the creation of innovations, the relevant areas of research, the granting of preferences to cluster participants. The creation of technoparks suggests the presence of a specially allocated site, which houses many new businesses, so that existing institutions can only be partners of the technopark. From the point of view of commercialization of University innovation, the cluster seems to be a more attractive method compared with the creation of technology parks, but its application is necessary to adjust the approach to conducting the state policy in the field of innovation management. The interaction of universities and enterprises via an intermediary – the chamber of commerce and industry – can be described as an obstacle to the commercialization of university innovations. On the contrary, technological innovation center protects the interests of universities, rather than enterprises, as it is created to facilitate the commercialization of university innovation. Direct interaction of universities and enterprises becomes possible with the help of methods of a single transaction, a regular cooperation and a contract for the supply of innovation. The choice of methods of commercialization of innovations should be made on the basis of existing university

  14. 75 FR 32983 - Commercial Driver's License (CDL) Standards: Exemption

    Science.gov (United States)

    2010-06-10

    ...-28480] Commercial Driver's License (CDL) Standards: Exemption AGENCY: Federal Motor Carrier Safety... commercial driver's license (CDL) as required by current regulations. FMCSA reviewed NAAA's application for... demonstrate alternatives its members would employ to ensure that their commercial motor vehicle (CMV) drivers...

  15. Satellite Communications Using Commercial Protocols

    Science.gov (United States)

    Ivancic, William D.; Griner, James H.; Dimond, Robert; Frantz, Brian D.; Kachmar, Brian; Shell, Dan

    2000-01-01

    NASA Glenn Research Center has been working with industry, academia, and other government agencies in assessing commercial communications protocols for satellite and space-based applications. In addition, NASA Glenn has been developing and advocating new satellite-friendly modifications to existing communications protocol standards. This paper summarizes recent research into the applicability of various commercial standard protocols for use over satellite and space- based communications networks as well as expectations for future protocol development. It serves as a reference point from which the detailed work can be readily accessed. Areas that will be addressed include asynchronous-transfer-mode quality of service; completed and ongoing work of the Internet Engineering Task Force; data-link-layer protocol development for unidirectional link routing; and protocols for aeronautical applications, including mobile Internet protocol routing for wireless/mobile hosts and the aeronautical telecommunications network protocol.

  16. Personalized skincare: from molecular basis to clinical and commercial applications

    Directory of Open Access Journals (Sweden)

    Markiewicz E

    2018-04-01

    Full Text Available Ewa Markiewicz, Olusola Clement Idowu Research & Development, Hexis Lab, Science Central, The Core, Bath Lane, Newcastle upon Tyne, UK Abstract: Individual responses of human skin to the environmental stress are determined by differences in the anatomy and physiology that are closely linked to the genetic characteristics such as pigmentation. Ethnic skin phenotypes can be distinguished based on defined genotypic traits, structural organization and compartmentalized sensitivity to distinct extrinsic aging factors. These differences are not only responsible for the variation in skin performance after exposure to damaging conditions, but can also affect the mechanisms of drug absorption, sensitization and other longer term effects. The unique characteristics of the individual skin function and, particularly, of the ethnic skin type are currently considered to shape the future of clinical and pharmacologic interventions as a basis for personalized skincare. Individual approaches to skincare render a novel and actively growing area with a range of biomedical and commercial applications within cosmetics industry. In this review, we summarize the aspects of the molecular and clinical manifestations of the environmental stress on human skin and proposed protective mechanisms that are linked to ethnic differences and pathophysiology of extrinsic skin aging. We subsequently discuss the possible applications and translation of this knowledge into personalized skincare. Keywords: pigmentation, gene polymorphism, photodamage, environmental stress, cosmetics

  17. Application of text mining for customer evaluations in commercial banking

    Science.gov (United States)

    Tan, Jing; Du, Xiaojiang; Hao, Pengpeng; Wang, Yanbo J.

    2015-07-01

    Nowadays customer attrition is increasingly serious in commercial banks. To combat this problem roundly, mining customer evaluation texts is as important as mining customer structured data. In order to extract hidden information from customer evaluations, Textual Feature Selection, Classification and Association Rule Mining are necessary techniques. This paper presents all three techniques by using Chinese Word Segmentation, C5.0 and Apriori, and a set of experiments were run based on a collection of real textual data that includes 823 customer evaluations taken from a Chinese commercial bank. Results, consequent solutions, some advice for the commercial bank are given in this paper.

  18. Association of viable Mycobacterium leprae with Type 1 reaction in leprosy.

    Science.gov (United States)

    Save, Mrudula Prakash; Dighe, Anju Rajaram; Natrajan, Mohan; Shetty, Vanaja Prabhakaran

    2016-03-01

    The working hypothesis is that, viable Mycobacterium leprae (M. leprae) play a crucial role in the precipitation of Type 1 reaction (T1R) in leprosy. A total of 165 new multibacillary patients were studied. To demonstrate presence of viable M. leprae in reactional lesion (T1R+), three tests were used concurrently viz. growth in the mouse foot pad (MFP), immunohistochemical detection of M. leprae secretory protein Ag85, and 16s rRNA--using in situ RT-PCR. Mirror biopsies and non reactional lesions served as controls (T1R-). A significantly higher proportion of lesion biopsy homogenates obtained at onset, from T1R(+) cases have shown unequivocal growth in MFP, proving the presence of viable bacteria, as compared to T1R(-) (P leprae is a component/prerequisite and the secretory protein Ag 85, might be the trigger for precipitation of T1R.

  19. Radiation disinfestation: A viable technology for developing countries

    International Nuclear Information System (INIS)

    Loaharanu, P.

    1985-01-01

    Increasing food production in many countries is often offset by spoilage losses that occur at different stages after harvesting, slaughtering, or catching. The situation becomes critical in developing countries as more food is needed to feed the ever-increasing population. One of the major problems of losses of food and agricultural products during storage is insect infestation. This paper reviews some insect infestation problems of valuable crops in developing countries such as cereals, pulses, dried fish and meat, fresh and dried fruits, coffee and cocoa beans, spices, and cured tobacco leaves. Present practices of chemical fumigation to eliminate insect problems in these crops give rise to concern from the points of view of both public health and occupational safety. Irradiation technology has been shown to be as effective as other insect disinfestation methods and could provide a viable alternative for this purpose. Insects do not develop resistance to physical techniques such as heat or irradiation as they do to chemical treatments. Applications of radiation for disinfestation of food and agricultural products of importance to developing countries are discussed. The economics of radiation disinfestation of cereals and pulses, dried fish, and fresh fruits are also discussed

  20. Viable adhered Staphylococcus aureus highly reduced on novel antimicrobial sutures using chlorhexidine and octenidine to avoid surgical site infection (SSI)

    Science.gov (United States)

    Schneider, Jochen; Harrasser, Norbert; Tübel, Jutta; Mühlhofer, Heinrich; Pförringer, Dominik; von Deimling, Constantin; Foehr, Peter; Kiefel, Barbara; Krämer, Christina; Stemberger, Axel; Schieker, Matthias

    2018-01-01

    Background Surgical sutures can promote migration of bacteria and thus start infections. Antiseptic coating of sutures may inhibit proliferation of adhered bacteria and avoid such complications. Objectives This study investigated the inhibition of viable adhering bacteria on novel antimicrobially coated surgical sutures using chlorhexidine or octenidine, a critical factor for proliferation at the onset of local infections. The medical need, a rapid eradication of bacteria in wounds, can be fulfilled by a high antimicrobial efficacy during the first days after wound closure. Methods As a pretesting on antibacterial efficacy against relevant bacterial pathogens a zone of inhibition assay was conducted with middle ranged concentrated suture coatings (22 μg/cm). For further investigation of adhering bacteria in detail the most clinically relevant Staphylococcus aureus (ATCC®49230™) was used. Absorbable braided sutures were coated with chlorhexidine-laurate, chlorhexidine-palmitate, octenidine-laurate, and octenidine-palmitate. Each coating type resulted in 11, 22, or 33 μg/cm drug content on sutures. Scanning electron microscopy (SEM) was performed once to inspect the coating quality and twice to investigate if bacteria have colonized on sutures. Adhesion experiments were assessed by exposing coated sutures to S. aureus suspensions for 3 h at 37°C. Subsequently, sutures were sonicated and the number of viable bacteria released from the suture surface was determined. Furthermore, the number of viable planktonic bacteria was measured in suspensions containing antimicrobial sutures. Commercially available sutures without drugs (Vicryl®, PGA Resorba®, and Gunze PGA), as well as triclosan-containing Vicryl® Plus were used as control groups. Results Zone of inhibition assay documented a multispecies efficacy of novel coated sutures against tested bacterial strains, comparable to most relevant S. aureus over 48 hours. SEM pictures demonstrated uniform layers on

  1. Residential-commercial energy input estimation based on genetic algorithm (GA) approaches: an application of Turkey

    International Nuclear Information System (INIS)

    Ozturk, H.K.; Canyurt, O.E.; Hepbasli, A.; Utlu, Z.

    2004-01-01

    The main objective of the present study is to develop the energy input estimation equations for the residential-commercial sector (RCS) in order to estimate the future projections based on genetic algorithm (GA) notion and to examine the effect of the design parameters on the energy input of the sector. For this purpose, the Turkish RCS is given as an example. The GA Energy Input Estimation Model (GAEIEM) is used to estimate Turkey's future residential-commercial energy input demand based on gross domestic product (GDP), population, import, export, house production, cement production and basic house appliances consumption figures. It may be concluded that the three various forms of models proposed here can be used as an alternative solution and estimation techniques to available estimation techniques. It is also expected that this study will be helpful in developing highly applicable and productive planning for energy policies. (author)

  2. Issues of organizational cybernetics and viability beyond Beer's viable systems model

    Science.gov (United States)

    Nechansky, Helmut

    2013-11-01

    The paper starts summarizing the claims of Beer's viable systems model to identify five issues any viable organizations has to deal with in an unequivocal hierarchical structure of five interrelated systems. Then the evidence is introduced for additional issues and related viable structures of organizations, which deviate from Beer's model. These issues are: (1) the establishment and (2) evolution of an organization; (3) systems for independent top-down control (like "Six Sigma"); (4) systems for independent bottom-up correction of performance problems (like "Kaizen"), both working outside a hierarchical structure; (5) pull production systems ("Just in Time") and (6) systems for checks and balances of top-level power (like boards and shareholder meetings). Based on that an evolutionary approach to organizational cybernetics is outlined, addressing the establishment of organizations and possible courses of developments, including recent developments in quality and production engineering, as well as problems of setting and changing goal values determining organizational policies.

  3. Formas cocoides de Helicobacter pylori: viables o degenerativas

    Directory of Open Access Journals (Sweden)

    Felipe Cava

    2003-06-01

    Full Text Available De los trabajos presentados acerca de las formas cocoides de Helicobacter pylori se deduce una controversia mucho mayor que la resultante del mero estudio clínico de este microorganismo. Parece claro que existe una conversión tanto in vivo como in vitro de las formas espirales a las formas cocoides inducida por varios motivos, como cultivos prolongados, estrés físico y químico, y agentes antimicrobianos. En esta revisión repasamos los puntos de vista que han dividido a investigadores de esta área en dos grupos bien definidos: Los que consideran a estas formas cocoides como un producto no viable de degeneración celular y los que piensan que estas formas son estructuras viables,durmientes o de resistencia frente a condiciones ambientales adversas. Esta discrepancia conlleva a que interrogantes sobre la relación entre la transmisión de la enfermedad y estas formas cocoides permanezcan sin respuesta todavía.

  4. Accelerating the commercialization of biomass energy generation within New York State

    Energy Technology Data Exchange (ETDEWEB)

    Proakis, G.J. [New York State Technology Enterprise Corp., Rome, NY (United States); Vasselli, J.J. [Syracuse Research Corp., North Syracuse, NY (United States); Neuhauser, E. [Niagara Mohawk Power Corp., Syracuse, NY (United States); Volk, T.A. [State University of New York, Syracuse, NY (United States)

    1999-07-01

    A significant obstacle to establishing a commercially viable, self-sustaining willow biomass industry is the initial capital investment required to establish the crop. One approach to overcoming this challenge is an incentive program to reduce the initial capital investment costs for landowners. This study quantifies the start-up investment costs, economic development impact, and environmental pollution reduction benefits associated with the creation of a biomass energy industry in New York State. The study recommends the creation of a state-sponsored revolving loan fund that would be used by landowners to finance the cost of establishing willow biomass crops. (author)

  5. Commercial Spacewalking: Designing an EVA Qualification Program for Space Tourism

    Science.gov (United States)

    Gast, Matthew A.

    2010-01-01

    In the near future, accessibility to space will be opened to anyone with the means and the desire to experience the weightlessness of microgravity, and to look out upon both the curvature of the Earth and the blackness of space, from the protected, shirt-sleeved environment of a commercial spacecraft. Initial forays will be short-duration, suborbital flights, but the experience and expertise of half a century of spaceflight will soon produce commercial vehicles capable of achieving low Earth orbit. Even with the commercial space industry still in its infancy, and manned orbital flight a number of years away, there is little doubt that there will one day be a feasible and viable market for those courageous enough to venture outside the vehicle and into the void, wearing nothing but a spacesuit, armed with nothing but preflight training. What that Extravehicular Activity (EVA) preflight training entails, however, is something that has yet to be defined. A number of significant factors will influence the composition of a commercial EVA training program, but a fundamental question remains: 'what minimum training guidelines must be met to ensure a safe and successful commercial spacewalk?' Utilizing the experience gained through the development of NASA's Skills program - designed to qualify NASA and International Partner astronauts for EVA aboard the International Space Station - this paper identifies the attributes and training objectives essential to the safe conduct of an EVA, and attempts to conceptually design a comprehensive training methodology meant to represent an acceptable qualification standard.

  6. Bulk-Heterojunction Organic Solar Cells: Five Core Technologies for Their Commercialization.

    Science.gov (United States)

    Kang, Hongkyu; Kim, Geunjin; Kim, Junghwan; Kwon, Sooncheol; Kim, Heejoo; Lee, Kwanghee

    2016-09-01

    The past two decades of vigorous interdisciplinary approaches has seen tremendous breakthroughs in both scientific and technological developments of bulk-heterojunction organic solar cells (OSCs) based on nanocomposites of π-conjugated organic semiconductors. Because of their unique functionalities, the OSC field is expected to enable innovative photovoltaic applications that can be difficult to achieve using traditional inorganic solar cells: OSCs are printable, portable, wearable, disposable, biocompatible, and attachable to curved surfaces. The ultimate objective of this field is to develop cost-effective, stable, and high-performance photovoltaic modules fabricated on large-area flexible plastic substrates via high-volume/throughput roll-to-roll printing processing and thus achieve the practical implementation of OSCs. Recently, intensive research efforts into the development of organic materials, processing techniques, interface engineering, and device architectures have led to a remarkable improvement in power conversion efficiencies, exceeding 11%, which has finally brought OSCs close to commercialization. Current research interests are expanding from academic to industrial viewpoints to improve device stability and compatibility with large-scale printing processes, which must be addressed to realize viable applications. Here, both academic and industrial issues are reviewed by highlighting historically monumental research results and recent state-of-the-art progress in OSCs. Moreover, perspectives on five core technologies that affect the realization of the practical use of OSCs are presented, including device efficiency, device stability, flexible and transparent electrodes, module designs, and printing techniques. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Use of advanced commercial ICs (COTS) for space application

    International Nuclear Information System (INIS)

    Strobel, D.J.; Czajkowski, D.R.; Layton, P.; Shanken, S.

    1999-01-01

    A product line of space-qualified radiation-tolerant ICs based on a high-volume commercial-off-the-shelf (COTS) silicon has been developed. The basic results from over 300 lots of COTS silicon, assembled and screened to Class B and Class S requirements will be presented. Intelligent use of commercial ICs engineered to improve radiation performance, is effective in introducing advanced technology to new satellite systems. Space Electronics has introduced over 125 space-qualified microelectronics standard products, that are used on over 90 space projects. (authors)

  8. Future trends in commercial and military systems

    Science.gov (United States)

    Bond, F. E.

    Commercial and military satellite communication systems are addressed, with a review of current applications and typical communication characteristics of the space and earth segments. Drivers for the development of future commercial systems include: the pervasion of digital techniques and services, growing orbit and frequency congestion, demand for more entertainment, and the large potential market for commercial 'roof-top' service. For military systems, survivability, improved flexibility, and the need for service to small mobile terminals are the principal factors involved. Technical trends include the use of higher frequency bands, multibeam antennas and a significant increase in the application of onboard processing. Military systems will employ a variety of techniques to counter both physical and electronic threats. The use of redundant transmission paths is a particularly effective approach. Successful implementation requires transmission standards to achieve the required interoperability among the pertinent networks. For both the military and commercial sectors, the trend toward larger numbers of terminals and more complex spacecraft is still persisting.

  9. Magnetic giant magnetoresistance commercial off the shelf for space applications

    DEFF Research Database (Denmark)

    Michelena, M.D.; Oelschlägel, Wulf; Arruego, I.

    2008-01-01

    The increase of complexity and miniaturizing level of Aerospace platforms make use of commercial off the shelf (COTS) components constitute a plausible alternative to the use of military or rad-tolerant components. In this work, giant magnetoresistance commercial sensors are studied to be used as......-375 mu T biasing field. (c) 2008 American Institute of Physics....

  10. Commercial Applications of X Ray Spectrometric Techniques

    International Nuclear Information System (INIS)

    Wegrzynek, D.

    2013-01-01

    In the 21st century, the X-ray fluorescence (XRF) technique is widely used in process control, industrial applications and for routine elemental analysis. The technique has a multielement capability capable of detecting elements with Z ≥ 10, with a few instruments capable of detecting also elements with Z ≥ 5. It is characterized by a non-destructive analysis process and relatively good detection limits, typically one part per million, for a wide range of elements. The first commercial XRF instruments were introduced to the market about 50 years ago. They were the wavelength dispersive X ray fluorescence (WDXRF) spectrometers utilizing Bragg’s law and reflection on crystal lattices for sequential elemental analysis of sample composition. The advances made in radiation detector technology, especially the introduction of semiconductor detectors, improvements in signal processing electronics, availability and exponential growth of personal computer market led to invention of energy dispersive X ray fluorescence (EDXRF) technique. The EDXRF is more cost effective as compared to WDXRF. It also allows for designing compact instruments. Such instruments can be easily tailored to the needs of different customers, integrated with industrial installations, and also miniaturized for the purpose of in-situ applications. The versatility of the technique has been confirmed in a spectacular way by using the XRF and X-ray spectrometric techniques, among few others, during the NASA and ESA missions in search for the evidence of life and presence of water on the surface of Mars. The XRF technique has achieved its strong position within the atomic spectroscopy group of analytical techniques not only due to its versatility but also due to relatively low running costs, as compared to the commonly used methods, e.g., atomic absorption spectrometry (AAS) or inductively coupled plasma atomic emission/mass spectrometry (ICP-AES/MS). Presently, the XRF technique together with X ray

  11. Advances in commercial application of gamma radiation in tropical fruits at Brazil

    Science.gov (United States)

    Sabato, S. F.; Silva, J. M.; Cruz, J. N.; Broisler, P. O.; Rela, P. R.; Salmieri, S.; Lacroix, M.

    2009-07-01

    All regions of Brazil are potential areas for growing tropical fruits. As this country is already a great producer and exporter of tropical fruits, ionizing radiation has been the subject of studies in many commodities. An important project has been carried out to increase the commercial use of gamma radiation in our country. Instituto de Pesquisas Energeticas e Nucleares (IPEN)-CNEN/SP together with field producers in northeast region and partners like International Atomic Energy Agency (IAEA), CIC, Empresa Brasileira Pesquisa na Agricultura (EMBRAPA) joined to demonstrate this technology, its application and commercial feasibility. The objective of this study is to show advances in feasibility demonstrate the quality of the irradiated fruits in an international consignment from Brazil to Canada. In this work, Tommy Atkins mangoes harvested in northeast region of Brazil were sent to Canada. The fruits were treated in a gamma irradiation facility at doses 0.4 and 1.0 kGy. The control group was submitted to hydrothermal treatment (46 °C for 110 min). The fruits were stored at 11 °C for 10 days until the international transportation and kept at an environmental condition (22 °C) for 12 days, where their physical-chemical and sensorial properties were evaluated. The financial part of the feasibility study covers the scope of the investment, including the net working capital and production costs.

  12. Advances in commercial application of gamma radiation in tropical fruits at Brazil

    International Nuclear Information System (INIS)

    Sabato, S.F.; Silva, J.M.; Cruz, J.N.; Broisler, P.O.; Rela, P.R.; Salmieri, S.; Lacroix, M.

    2009-01-01

    All regions of Brazil are potential areas for growing tropical fruits. As this country is already a great producer and exporter of tropical fruits, ionizing radiation has been the subject of studies in many commodities. An important project has been carried out to increase the commercial use of gamma radiation in our country. Instituto de Pesquisas Energeticas e Nucleares (IPEN)-CNEN/SP together with field producers in northeast region and partners like International Atomic Energy Agency (IAEA), CIC, Empresa Brasileira Pesquisa na Agricultura (EMBRAPA) joined to demonstrate this technology, its application and commercial feasibility. The objective of this study is to show advances in feasibility demonstrate the quality of the irradiated fruits in an international consignment from Brazil to Canada. In this work, Tommy Atkins mangoes harvested in northeast region of Brazil were sent to Canada. The fruits were treated in a gamma irradiation facility at doses 0.4 and 1.0 kGy. The control group was submitted to hydrothermal treatment (46 o C for 110 min). The fruits were stored at 11 o C for 10 days until the international transportation and kept at an environmental condition (22 o C) for 12 days, where their physical-chemical and sensorial properties were evaluated. The financial part of the feasibility study covers the scope of the investment, including the net working capital and production costs.

  13. The Rise and Demise of Commercial Geography.

    Science.gov (United States)

    Handley, Lawrence R.

    1982-01-01

    Commercial geography, originally taught in 18th-century trading schools, reached its zenith in the mid-1920s because it was stimulated by the development of the British Empire, noted for its commercial applications, and popularized through information disseminated by geographical societies. Demise factors include America's isolationist attitudes,…

  14. Commercial technologies from the SP-100 program

    International Nuclear Information System (INIS)

    Truscello, V.C.; Fujita, T.; Mondt, J.F.

    1995-01-01

    For more than a decade, Jet Propulsion Labortory and Los Alamos have managed a multi-agency funded effort to develop a space reactor power system. This SP-100 Program has developed technologies required for space power systems that can be implemented in the industrial and commercial sectors to improve competitiveness in the global economy. Initial steps taken to transfer this technology from the laboratories to industrial and commercial entities within United States include: (1) identifying specific technologies having commercial potential; (2) distributing information describing the identified technologies and interacting with interested commercial and industrial entities to develop application-specific details and requirements; and (3) providing a technological data base that leads to transfer of technology or the forming of teaming arrangements to accomplish the transfer by tailoring the technology to meet application-specific requirements. SP-100 technologies having commercial potential encompass fabrication processes, devices, and components. Examples: a process for bonding refractory metals to graphite, a device to sense the position of an actuator and a component to enable rotating machines to operate without supplying lubrication (self-lubricating ball bearing). Shortly after the NASA Regional Technology Transfer Centers widely disseminated information covering SP-100 technologies, over one hundred expressions of interest were received, which indicate that there is a large potential benefit in transferring SP-100 technology. Interactions with industrial and commercial entities have identified a substantial need for creating teaming arrangements involving the interested entity and personnel from laboratories and their contractors, who have the knowledge and ability to tailor the technology to meet application-specific requirements. copyright 1995 American Institute of Physics

  15. Applications of Radiation Processing in Industry

    International Nuclear Information System (INIS)

    Abad, Lucille V.

    2015-01-01

    Radiation processing has long been known as commercially viable technology that can be beneficially used to enhance the characteristics of many materials. Several gamma irradiators and electron beam accelerators are operating worldwide which are utilized for various established industrial applications. These could be used for the following processes: a) radiation crosslinking e.g. crosslinking of wires and cables, heat shrinkable film and tube productions, manufacture of plastic bags and tubings for medical products, pre-curing of automobile tire components, curing of polymeric coatings, etc. b) radiation degradation e.g. Scrap Teflon (Polytetraflouroethylene) to form powders, disinfestations and pasteurization of agricultural products, sterilization of medical products, etc.; and c) radiation grafting e.g. grafted non-woven fabrics for metal adsorbent. Emerging applications for radiation processing include grafted membranes for fuel cell, electrodes, cell sheet for tissue engineering, nanoparticle production, polymer composite synthesis, and fibrous catalyst for biodiesel production. Current researches at the Philippine Nuclear Research Institute consist of crosslinking of natural and synthetic polymers for medical application e.g. wound dressing, hemostats, and bioimplants for vesicouretal reflux (VUR); grafting of natural and synthetic fabrics for metal adsorbents; and radiation degradation of carrageenan as plant growth promoter. (author)

  16. Commercial future: making remote sensing a media event

    Science.gov (United States)

    Lurie, Ian

    1999-12-01

    The rapid growth of commercial remote sensing has made high quality digital sensing data widely available -- now, remote sensing must become and remain a strong, commercially viable industry. However, this new industry cannot survive without an educated consumer base. To access markets, remote sensing providers must make their product more accessible, both literally and figuratively: Potential customers must be able to find the data they require, when they require it, and they must understand the utility of the information available to them. The Internet and the World Wide Web offer the perfect medium to educate potential customers and to sell remote sensing data to those customers. A well-designed web presence can provide both an information center and a market place for companies offering their data for sale. A very high potential web-based market for remote sensing lies in media. News agencies, web sites, and a host of other visual media services can use remote sensing data to provide current, relevant information regarding news around the world. This paper will provide a model for promotion and sale of remote sensing data via the Internet.

  17. Applications of commercial biosensors in clinical, food, environmental, and biothreat/biowarfare analyses.

    Science.gov (United States)

    Bahadır, Elif Burcu; Sezgintürk, Mustafa Kemal

    2015-06-01

    The lack of specific, low-cost, rapid, sensitive, and easy detection of biomolecules has resulted in the development of biosensor technology. Innovations in biosensor technology have enabled many biosensors to be commercialized and have enabled biomolecules to be detected onsite. Moreover, the emerging technologies of lab-on-a-chip microdevices and nanosensors offer opportunities for the development of new biosensors with much better performance. Biosensors were first introduced into the laboratory by Clark and Lyons. They developed the first glucose biosensor for laboratory conditions. Then in 1973, a glucose biosensor was commercialized by Yellow Springs Instruments. The commercial biosensors have small size and simple construction and they are ideal for point-of-care biosensing. In addition to glucose, a wide variety of metabolites such as lactate, cholesterol, and creatinine can be detected by using commercial biosensors. Like the glucose biosensors (tests) other commercial tests such as for pregnancy (hCG), Escherichia coli O157, influenza A and B viruses, Helicobacter pylori, human immunodeficiency virus, tuberculosis, and malaria have achieved success. Apart from their use in clinical analysis, commercial tests are also used in environmental (such as biochemical oxygen demand, nitrate, pesticide), food (such as glutamate, glutamine, sucrose, lactose, alcohol, ascorbic acid), and biothreat/biowarfare (Bacillus anthracis, Salmonella, Botulinum toxin) analysis. In this review, commercial biosensors in clinical, environmental, food, and biowarfare analysis are summarized and the commercial biosensors are compared in terms of their important characteristics. This is the first review in which all the commercially available tests are compiled together. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Models for residential- and commercial-sector energy-conservation analysis: applications, limitations, and future potential. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Cole, Henry E.; Fullen, Robert E.

    1980-09-01

    This report reviews four of the major models used by the Department of Energy (DOE) for energy conservation analyses in the residential- and commercial-building sectors. The objective is to provide a critical analysis of how these models can serve as tools for DOE and its Conservation Policy Office in evaluating and quantifying their policy and program requirements. For this, the study brings together information on the models' analytical structure and their strengths and limitations in policy applications these are then employed to assess the most-effective role for each model in addressing future issues of buildings energy-conservation policy and analysis. The four models covered are: Oak Ridge Residential Energy Model; Micro Analysis of Transfers to Households/Comprehensive Human Resources Data System (MATH/CHRDS) Model; Oak Ridge Commercial Energy Model; and Brookhaven Buildings Energy Conservation Optimization Model (BECOM).

  19. Membrane Lipids as Indicators for Viable Bacterial Communities Inhabiting Petroleum Systems.

    Science.gov (United States)

    Gruner, Andrea; Mangelsdorf, Kai; Vieth-Hillebrand, Andrea; Horsfield, Brian; van der Kraan, Geert M; Köhler, Thomas; Janka, Christoph; Morris, Brandon E L; Wilkes, Heinz

    2017-08-01

    Microbial activity in petroleum reservoirs has been implicated in a suite of detrimental effects including deterioration of petroleum quality, increases in oil sulfur content, biofouling of steel pipelines and other infrastructures, and well plugging. Here, we present a biogeochemical approach, using phospholipid fatty acids (PLFAs), for detecting viable bacteria in petroleum systems. Variations within the bacterial community along water flow paths (producing well, topside facilities, and injection well) can be elucidated in the field using the same technique, as shown here within oil production plants in the Molasse Basin of Upper Austria. The abundance of PLFAs is compared to total cellular numbers, as detected by qPCR of the 16S rDNA gene, to give an overall comparison between the resolutions of both methods in a true field setting. Additionally, the influence of biocide applications on lipid- and DNA-based quantification was investigated. The first oil field, Trattnach, showed significant PLFA abundances and cell numbers within the reservoir and topside facilities. In contrast, the second field (Engenfeld) showed very low PLFA levels overall, likely due to continuous treatment of the topside facilities with a glutaraldehyde-based antimicrobial. In comparison, Trattnach is dosed once per week in a batch fashion. Changes within PLFA compositions across the flow path, throughout the petroleum production plants, point to cellular adaptation within the system and may be linked to shifts in the dominance of certain bacterial types in oil reservoirs versus topside facilities. Overall, PLFA-based monitoring provides a useful tool to assess the abundance and high-level taxonomic diversity of viable microbial populations in oil production wells, topside infrastructure, pipelines, and other related facilities.

  20. Regional vegetation management standards for commercial pine ...

    African Journals Online (AJOL)

    Although the understanding gained from these trials allowed for the development of vegetation management standards, their operational and economic viability need to be tested on a commercial basis. Four pine trials were thus initiated to test the applicability of these standards when utilised on a commercial scale. Two of ...

  1. Intitutional constraints to fusion commercialization

    International Nuclear Information System (INIS)

    1979-10-01

    The major thrust of this report is that the long time frame associated with the development of commercial fusion systems in the context of the commercialization and institutional history of an allied technology, fission-power, suggests that fusion commercialization will not occur without active and broad-based support on the part of the Nation's political leaders. Its key recommendation is that DOE fusion planners devote considerable resources to analytical efforts aimed at determining the need for fusion and the timing of that need, in order to convince policymakers that they need do more than preserve fusion as an option for application at some indefinite point in the future. It is the thesis of the report that, in fact, an act of political vision on the part of the Nation's leaders will be required to accomplish fusion commercialization

  2. A viable dipole magnet concept with REBCO CORC® wires and further development needs for high-field magnet applications

    Science.gov (United States)

    Wang, Xiaorong; Caspi, Shlomo; Dietderich, Daniel R.; Ghiorso, William B.; Gourlay, Stephen A.; Higley, Hugh C.; Lin, Andy; Prestemon, Soren O.; van der Laan, Danko; Weiss, Jeremy D.

    2018-04-01

    REBCO coated conductors maintain a high engineering current density above 16 T at 4.2 K. That fact will significantly impact markets of various magnet applications including high-field magnets for high-energy physics and fusion reactors. One of the main challenges for the high-field accelerator magnet is the use of multi-tape REBCO cables with high engineering current density in magnet development. Several approaches developing high-field accelerator magnets using REBCO cables are demonstrated. In this paper, we introduce an alternative concept based on the canted cos θ (CCT) magnet design using conductor on round core (CORC®) wires that are wound from multiple REBCO tapes with a Cu core. We report the development and test of double-layer three-turn CCT dipole magnets using CORC® wires at 77 and 4.2 K. The scalability of the CCT design allowed us to effectively develop and demonstrate important magnet technology features such as coil design, winding, joints and testing with minimum conductor lengths. The test results showed that the CCT dipole magnet using CORC® wires was a viable option in developing a REBCO accelerator magnet. One of the critical development needs is to increase the engineering current density of the 3.7 mm diameter CORC® wire to 540 A mm-2 at 21 T, 4.2 K and to reduce the bending radius to 15 mm. This would enable a compact REBCO dipole insert magnet to generate a 5 T field in a background field of 16 T at 4.2 K.

  3. A Comprehensive Assessment of Biologicals Contained Within Commercial Airliner Cabin Air

    Science.gov (United States)

    LaDuc, Myron T.; Osman, Shariff; Dekas, Anne; Stuecker, Tara; Newcombe, Dave; Piceno, Yvette; Fuhrman, J.; Andersen, Gary; Venkateswaran, Kasthuri; Bearman, Greg

    2006-01-01

    Both culture-based and culture-independent, biomarker-targeted microbial enumeration and identification technologies were employed to estimate total microbial and viral burden and diversity within the cabin air of commercial airliners. Samples from each of twenty flights spanning three commercial carriers were collected via air-impingement. When the total viable microbial population was estimated by assaying relative concentrations of the universal energy carrier ATP, values ranged from below detection limits (BDL) to 4.1 x 106 cells/cubic m of air. The total viable microbial population was extremely low in both of Airline A (approximately 10% samples) and C (approximately 18% samples) compared to the samples collected aboard flights on Airline A and B (approximately 70% samples). When samples were collected as a function of time over the course of flights, a gradual accumulation of microbes was observed from the time of passenger boarding through mid-flight, followed by a sharp decline in microbial abundance and viability from the initiation of descent through landing. It is concluded in this study that only 10% of the viable microbes of the cabin air were cultivable and suggested a need to employ state-of-the art molecular assay that measures both cultivable and viable-but-non-cultivable microbes. Among the cultivable bacteria, colonies of Acinetobacter sp. were by far the most profuse in Phase I, and Gram-positive bacteria of the genera Staphylococcus and Bacillus were the most abundant during Phase II. The isolation of the human pathogens Acinetobacter johnsonii, A. calcoaceticus, Janibacter melonis, Microbacterium trichotecenolyticum, Massilia timonae, Staphylococcus saprophyticus, Corynebacterium lipophiloflavum is concerning, as these bacteria can cause meningitis, septicemia, and a handful of sometimes fatal diseases and infections. Molecular microbial community analyses exhibited presence of the alpha-, beta-, gamma-, and delta- proteobacteria, as well as

  4. Commercial incineration demonstration

    International Nuclear Information System (INIS)

    Borduin, L.C.; Neuls, A.S.

    1981-01-01

    Low-level radioactive wastes (LLW) generated by nuclear utilities presently are shipped to commercial burial grounds for disposal. Substantially increasing shipping and disposal charges have sparked renewed industry interest in incineration and other advanced volume reduction techniques as potential cost-saving measures. Repeated inquiries from industry sources regarding LLW applicability of the Los Alamos controlled-air incineration (CAI) design led DOE to initiate this commercial demonstration program in FY-1980. The selected program approach to achieving CAI demonstration at a utility site is a DOE sponsored joint effort involving Los Alamos, a nuclear utility, and a liaison subcontractor. Required development tasks and responsibilities of the particpants are described. Target date for project completion is the end of FY-1985

  5. Research achievements and commercial interaction

    International Nuclear Information System (INIS)

    Garnett, H.M.

    2001-01-01

    ANSTO, in partnership with Australian and overseas organisations, continues to make significant contributions to selected fields of research and development. Major revenue for ANSTO is generated through sales of radiopharmaceuticals and radioisotopes for medical, industrial, environmental and research purposes and through neutron irradiation services. Further, ANSTO is actively trying to generate maximum value from its knowledge and know-how through protection and exploitation of its intellectual property. Strategic alliances have been developed to further the commercial utilisation of ANSTO know-how in, for example, delivery systems for tumour treatments, commercial waste remediation and applications of plasma implantation. The 2000-2001 financial year saw the establishment of an ANSTO business unit called Sulfide Solutions targeted at better management of environmental issues arising from mining operations. Overall, ANSTO's capacity to generate value from the application of its knowledge and know-how is being increasingly acknowledged, the organisation attaining credibility as an international leader in the application of nuclear science and technology in targeted areas

  6. Commercialization of nanotechnology.

    Science.gov (United States)

    Hobson, David W

    2009-01-01

    The emerging and potential commercial applications of nanotechnologies clearly have great potential to significantly advance and even potentially revolutionize various aspects of medical practice and medical product development. Nanotechnology is already touching upon many aspects of medicine, including drug delivery, diagnostic imaging, clinical diagnostics, nanomedicines, and the use of nanomaterials in medical devices. This technology is already having an impact; many products are on the market and a growing number is in the pipeline. Momentum is steadily building for the successful development of additional nanotech products to diagnose and treat disease; the most active areas of product development are drug delivery and in vivo imaging. Nanotechnology is also addressing many unmet needs in the pharmaceutical industry, including the reformulation of drugs to improve their bioavailability or toxicity profiles. The advancement of medical nanotechnology is expected to advance over at least three different generations or phases, beginning with the introduction of simple nanoparticulate and nanostructural improvements to current product and process types, then eventually moving on to nanoproducts and nanodevices that are limited only by the imagination and limits of the technology itself. This review looks at some recent developments in the commercialization of nanotechnology for various medical applications as well as general trends in the industry, and explores the nanotechnology industry that is involved in developing medical products and procedures with a view toward technology commercialization. (c) 2009 John Wiley & Sons, Inc.

  7. Transitioning glass-ceramic scintillators for diagnostic x-ray imaging from the laboratory to commercial scale

    Science.gov (United States)

    Beckert, M. Brooke; Gallego, Sabrina; Elder, Eric; Nadler, Jason

    2016-10-01

    This study sought to mitigate risk in transitioning newly developed glass-ceramic scintillator technology from a laboratory concept to commercial product by identifying the most significant hurdles to increased scale. These included selection of cost effective raw material sources, investigation of process parameters with the most significant impact on performance, and synthesis steps that could see the greatest benefit from participation of an industry partner that specializes in glass or optical component manufacturing. Efforts focused on enhancing the performance of glass-ceramic nanocomposite scintillators developed specifically for medical imaging via composition and process modifications that ensured efficient capture of incident X-ray energy and emission of scintillation light. The use of cost effective raw materials and existing manufacturing methods demonstrated proof-of-concept for economical viable alternatives to existing benchmark materials, as well as possible disruptive applications afforded by novel geometries and comparatively lower cost per volume. The authors now seek the expertise of industry to effectively navigate the transition from laboratory demonstrations to pilot scale production and testing to evince the industry of the viability and usefulness of composite-based scintillators.

  8. Principles and application of high pressure-based technologies in the food industry.

    Science.gov (United States)

    Balasubramaniam, V M Bala; Martínez-Monteagudo, Sergio I; Gupta, Rockendra

    2015-01-01

    High pressure processing (HPP) has emerged as a commercially viable food manufacturing tool that satisfies consumers' demand for mildly processed, convenient, fresh-tasting foods with minimal to no preservatives. Pressure treatment, with or without heat, inactivates pathogenic and spoilage bacteria, yeast, mold, viruses, and also spores and extends shelf life. Pressure treatment at ambient or chilled temperatures has minimal impact on product chemistry. The product quality and shelf life are often influenced more by storage conditions and packaging material barrier properties than the treatment itself. Application of pressure reduces the thermal exposure of the food during processing, thereby protecting a variety of bioactive compounds. This review discusses recent scientific advances of high pressure technology for food processing and preservation applications such as pasteurization, sterilization, blanching, freezing, and thawing. We highlight the importance of in situ engineering and thermodynamic properties of food and packaging materials in process design. Current and potential future promising applications of pressure technology are summarized.

  9. A proposed acceptance process for commercial off-the-shelf (COTS) software in reactor applications

    International Nuclear Information System (INIS)

    Preckshot, G.G.; Scott, J.A.

    1996-03-01

    This paper proposes a process for acceptance of commercial off-the-shelf (COTS) software products for use in reactor systems important to safety. An initial set of four criteria establishes COTS software product identification and its safety category. Based on safety category, three sets of additional criteria, graded in rigor, are applied to approve/disapprove the product. These criteria fall roughly into three areas: product assurance, verification of safety function and safety impact, and examination of usage experience of the COTS product in circumstances similar to the proposed application. A report addressing the testing of existing software is included as an appendix

  10. Commercial applications for COIL

    Science.gov (United States)

    Solomon, Wayne C.; Carroll, David L.; King, D. M.; Fockler, L. A.; Stromberg, D. S.; Sexauer, M.; Milmoe, A.; Sentman, Lee H.

    2000-01-01

    The chemical oxygen-iodine laser (COIL) is a high power, fiber deliverable tool, which can be used for a number of different industrial applications. COIL is of particular interest because of its short fiber deliverable wavelength, high scaleable continuous wave power, and excellent material interaction properties. In past research the University of Illinois at Urbana-Champaign identified and decommissioning and decontamination (DD) of nuclear facilities as a primary focus for COIL technology. DD will be a major challenge in the coming decades. The use of a robotically driven fiber delivered cutting/ablation tool in contaminated areas promises to lower risks to workers for the DD mission. Further, the high cutting speed of COIL will significantly reduce the time required to cut contaminated equipment, reducing costs. The high power of COIL will permit the dismantling of thick stacks of piping and equipment as well as reactor vessels. COIL is very promising for the removal of material from contaminated surfaces, perhaps to depths thicker than an inch. Laser cutting and ablation minimizes dust and fumes, which reduces the required number of high efficiency particulate accumulator filters, thus reducing costly waste disposal. Other potential industrial applications for COIL are shipbuilding, automotive manufacturing, heavy machinery manufacturing, tasks requiring underwater cutting or welding, and there appear to be very promising applications for high powers lasers in the oil industry.

  11. Expression of proposed implantation marker genes CDX2 and HOXB7 in the blastocyst does not distinguish viable from non-viable human embryos

    DEFF Research Database (Denmark)

    Kirkegaard, Kirstine; Hindkjær, Johnny Juhl; Ingerslev, Hans Jakob

    2012-01-01

    expression differs between viable and non-viable embryos in both human and non-humans, suggesting transcriptome analysis of trophectoderm (TE) as a novel method of improving embryo selection. Potential candidate marker genes have been identified with array studies on animal blastocysts. The aim of this study...... was to investigate the expression of selected genes in human blastocysts in relation to the outcome of implantation. Materials and methods: Embryos from 10 oatients undergoing in vitro fertilization treatment were included in the project. A single blastocyst was chosen for biopsy on the morning of day 5 after oocyte...... of 15 key genes associated with developmental competence in animals were evaluated in high quality human embryos with monogenic or chromosomal disorders from a pre-implantation genetic disorder program. Triplicate cDNA amplifications for quantitative (q) RT-PCR were performed using pre-designed gene...

  12. Performance of commercial off-the-shelf microelectromechanical systems sensors in a pulsed reactor environment

    Energy Technology Data Exchange (ETDEWEB)

    Hobert, Keith Edwin [Los Alamos National Laboratory; Heger, Arlen S [Los Alamos National Laboratory; Mccready, Steven S [Los Alamos National Laboratory

    2010-07-15

    Prompted by the unexpected failure of piezoresistive sensors in both an elevated gamma-ray environment and reactor core pulse tests, we initiated radiation testing of several MEMS piezoresistive accelerometers and pressure transducers to ascertain their radiation hardness. Some commercial off-the-shelf sensors are found to be viable options for use in a high-energy pulsed reactor, but others suffer severe degradation and even catastrophic failure. Although researchers are promoting the use of MEMS devices in radiation-harsh environment, we nevertheless find assurance testing necessary.

  13. Development of economically viable, highly integrated, highly modular SEGIS architecture.

    Energy Technology Data Exchange (ETDEWEB)

    Enslin, Johan (Petra Solar, Inc., South Plainfield, NJ); Hamaoui, Ronald (Petra Solar, Inc., South Plainfield, NJ); Gonzalez, Sigifredo; Haddad, Ghaith (Petra Solar, Inc., South Plainfield, NJ); Rustom, Khalid (Petra Solar, Inc., South Plainfield, NJ); Stuby, Rick (Petra Solar, Inc., South Plainfield, NJ); Kuran, Mohammad (Petra Solar, Inc., South Plainfield, NJ); Mark, Evlyn (Petra Solar, Inc., South Plainfield, NJ); Amarin, Ruba (Petra Solar, Inc., South Plainfield, NJ); Alatrash, Hussam (Petra Solar, Inc., South Plainfield, NJ); Bower, Ward Isaac; Kuszmaul, Scott S.; Sena-Henderson, Lisa; David, Carolyn; Akhil, Abbas Ali

    2012-03-01

    Initiated in 2008, the SEGIS initiative is a partnership involving the U.S. DOE, Sandia National Laboratories, private sector companies, electric utilities, and universities. Projects supported under the initiative have focused on the complete-system development of solar technologies, with the dual goal of expanding renewable PV applications and addressing new challenges of connecting large-scale solar installations in higher penetrations to the electric grid. Petra Solar, Inc., a New Jersey-based company, received SEGIS funds to develop solutions to two of these key challenges: integrating increasing quantities of solar resources into the grid without compromising (and likely improving) power quality and reliability, and moving the design from a concept of intelligent system controls to successful commercialization. The resulting state-of-the art technology now includes a distributed photovoltaic (PV) architecture comprising AC modules that not only feed directly into the electrical grid at distribution levels but are equipped with new functions that improve voltage stability and thus enhance overall grid stability. This integrated PV system technology, known as SunWave, has applications for 'Power on a Pole,' and comes with a suite of technical capabilities, including advanced inverter and system controls, micro-inverters (capable of operating at both the 120V and 240V levels), communication system, network management system, and semiconductor integration. Collectively, these components are poised to reduce total system cost, increase the system's overall value and help mitigate the challenges of solar intermittency. Designed to be strategically located near point of load, the new SunWave technology is suitable for integration directly into the electrical grid but is also suitable for emerging microgrid applications. SunWave was showcased as part of a SEGIS Demonstration Conference at Pepco Holdings, Inc., on September 29, 2011, and is presently

  14. Assessment of the Energy Impacts of Outside Air in the Commercial Sector

    Energy Technology Data Exchange (ETDEWEB)

    Benne, K.; Griffith, B.; Long, N.; Torcellini, P.; Crawley, D.; Logee, T.

    2009-04-01

    The enormous quantity of energy consumed by U.S. commercial buildings places a significant burden on the energy supply and is a potential source of economic strain. To address this, the DOE Building Technologies Program has established the goal of developing market-viable zero energy buildings by 2025. This study focuses on the effects of outside air, and considers various outside air sources, types of building construction, building subsectors, and climates. Based on the information about energy consumption attributed to outside air, it identifies topics for further research that have the greatest potential to achieve energy savings.

  15. Commercialization of Plasma-Assisted Technologies: The Indian Experience

    Science.gov (United States)

    John, P. I.

    The paper describes an initiative by the Institute for Plasma Research (IPR), India in establishing links with the Indian industry for developing and commercialising advanced plasma-based industrial technologies. This has culminated in the creation of a self-financing technology development, incubation, demonstration and delivery facility. A business plan for converting the knowledge base to commercially viable technologies conceived technology as a product and the industry as the market and addressed issues like resistance to new technologies, the key role of entrepreneur, thrust areas and the necessity of technology incubation and delivery. Success of this strategy is discussed in a few case studies. We conclude by identifying the cost, environmental, strategic and techno-economic aspects, which would be the prime drivers for plasma-assisted manufacturing technology in India.

  16. Introducing Commercial Finance into the Water Sector in Developing Countries

    OpenAIRE

    Bender, Kevin

    2017-01-01

    This guidance note provides an introduction to the role of commercial finance in the water and sanitation sector. Its aim is to help readers (development specialists) explore applications in their own countries. The note focuses primarily on commercial bank loans, and throughout the document the term commercial finance refers to commercial loans from domestic banks. However, much of the gu...

  17. Bioethanol from poplar: a commercially viable alternative to fossil fuel in the European Union.

    Science.gov (United States)

    Littlewood, Jade; Guo, Miao; Boerjan, Wout; Murphy, Richard J

    2014-01-01

    The European Union has made it a strategic objective to develop its biofuels market in order to minimize greenhouse gas (GHG) emissions, to help mitigate climate change and to address energy insecurity within the transport sector. Despite targets set at national and supranational levels, lignocellulosic bioethanol production has yet to be widely commercialized in the European Union. Here, we use techno-economic modeling to compare the price of bioethanol produced from short rotation coppice (SRC) poplar feedstocks under two leading processing technologies in five European countries. Our evaluation shows that the type of processing technology and varying national costs between countries results in a wide range of bioethanol production prices (€0.275 to 0.727/l). The lowest production prices for bioethanol were found in countries that had cheap feedstock costs and high prices for renewable electricity. Taxes and other costs had a significant influence on fuel prices at the petrol station, and therefore the presence and amount of government support for bioethanol was a major factor determining the competitiveness of bioethanol with conventional fuel. In a forward-looking scenario, genetically engineering poplar with a reduced lignin content showed potential to enhance the competitiveness of bioethanol with conventional fuel by reducing overall costs by approximately 41% in four out of the five countries modeled. However, the possible wider phenotypic traits of advanced poplars needs to be fully investigated to ensure that these do not unintentionally negate the cost savings indicated. Through these evaluations, we highlight the key bottlenecks within the bioethanol supply chain from the standpoint of various stakeholders. For producers, technologies that are best suited to the specific feedstock composition and national policies should be optimized. For policymakers, support schemes that benefit emerging bioethanol producers and allow renewable fuel to be

  18. Image Analysis via Soft Computing: Prototype Applications at NASA KSC and Product Commercialization

    Science.gov (United States)

    Dominguez, Jesus A.; Klinko, Steve

    2011-01-01

    This slide presentation reviews the use of "soft computing" which differs from "hard computing" in that it is more tolerant of imprecision, partial truth, uncertainty, and approximation and its use in image analysis. Soft computing provides flexible information processing to handle real life ambiguous situations and achieve tractability, robustness low solution cost, and a closer resemblance to human decision making. Several systems are or have been developed: Fuzzy Reasoning Edge Detection (FRED), Fuzzy Reasoning Adaptive Thresholding (FRAT), Image enhancement techniques, and visual/pattern recognition. These systems are compared with examples that show the effectiveness of each. NASA applications that are reviewed are: Real-Time (RT) Anomaly Detection, Real-Time (RT) Moving Debris Detection and the Columbia Investigation. The RT anomaly detection reviewed the case of a damaged cable for the emergency egress system. The use of these techniques is further illustrated in the Columbia investigation with the location and detection of Foam debris. There are several applications in commercial usage: image enhancement, human screening and privacy protection, visual inspection, 3D heart visualization, tumor detections and x ray image enhancement.

  19. Catalog of Realizations for DXCCII using Commercially Available ICs and Applications

    Directory of Open Access Journals (Sweden)

    S. Maheshwari

    2012-04-01

    Full Text Available This paper presents fifteen distinct practical realizations for dual-X second generation current conveyor (DXCCII using commercially available integrated circuits. Detailed comparisons and results are presented to verify the utility of proposed realizations. The catalog of proposed realizations is a first attempt and is expected to be useful for testing newly developed circuits based on dual-X second generation current conveyor. Each of the first fourteen proposed realizations uses four ICs. One three IC based implementation is further given making the total count fifteen. Some additional features are also explored which further enhance the versatility of DXCCII. The paper further presents a novel and compact quadrature oscillator to verify the applicability of the proposed realizations. Single resistance control of the frequency of oscillation is also demonstrated by employing the new gain-variable DXCCII. Experimental results are also included along with simulation results to validate the proposed theory and its practical significance.

  20. Skills training workshops as a viable strategy for improving ...

    African Journals Online (AJOL)

    Skills training workshops as a viable strategy for improving smallholder and cooperative agribusiness management: A case study of Vhembe District, Limpopo Province, South Africa. ... South African Journal of Agricultural Extension ... Empirical evidence from this study shows that six months after attending the workshops, ...

  1. Keeping checkpoint/restart viable for exascale systems.

    Energy Technology Data Exchange (ETDEWEB)

    Riesen, Rolf E.; Bridges, Patrick G. (IBM Research, Ireland, Mulhuddart, Dublin); Stearley, Jon R.; Laros, James H., III; Oldfield, Ron A.; Arnold, Dorian (University of New Mexico, Albuquerque, NM); Pedretti, Kevin Thomas Tauke; Ferreira, Kurt Brian; Brightwell, Ronald Brian

    2011-09-01

    Next-generation exascale systems, those capable of performing a quintillion (10{sup 18}) operations per second, are expected to be delivered in the next 8-10 years. These systems, which will be 1,000 times faster than current systems, will be of unprecedented scale. As these systems continue to grow in size, faults will become increasingly common, even over the course of small calculations. Therefore, issues such as fault tolerance and reliability will limit application scalability. Current techniques to ensure progress across faults like checkpoint/restart, the dominant fault tolerance mechanism for the last 25 years, are increasingly problematic at the scales of future systems due to their excessive overheads. In this work, we evaluate a number of techniques to decrease the overhead of checkpoint/restart and keep this method viable for future exascale systems. More specifically, this work evaluates state-machine replication to dramatically increase the checkpoint interval (the time between successive checkpoint) and hash-based, probabilistic incremental checkpointing using graphics processing units to decrease the checkpoint commit time (the time to save one checkpoint). Using a combination of empirical analysis, modeling, and simulation, we study the costs and benefits of these approaches on a wide range of parameters. These results, which cover of number of high-performance computing capability workloads, different failure distributions, hardware mean time to failures, and I/O bandwidths, show the potential benefits of these techniques for meeting the reliability demands of future exascale platforms.

  2. Commercial application of rainfall simulation

    Science.gov (United States)

    Loch, Rob J.

    2010-05-01

    Landloch Pty Ltd is a commercial consulting firm, providing advice on a range of land management issues to the mining and construction industries in Australia. As part of the company's day-to-day operations, rainfall simulation is used to assess material erodibility and to investigate a range of site attributes. (Landloch does carry out research projects, though such are not its core business.) When treated as an everyday working tool, several aspects of rainfall simulation practice are distinctively modified. Firstly, the equipment used is regularly maintained, and regularly upgraded with a primary focus on ease, safety, and efficiency of use and on reliability of function. As well, trained and experienced technical support is considered essential. Landloch's chief technician has over 10 years experience in running rainfall simulators at locations across Australia and in Africa and the Pacific. Secondly, the specific experimental conditions established for each set of rainfall simulator runs are carefully considered to ensure that they accurately represent the field conditions to which the data will be subsequently applied. Considerations here include: • wetting and drying cycles to ensure material consolidation and/or cementation if appropriate; • careful attention to water quality if dealing with clay soils or with amendments such as gypsum; • strong focus on ensuring that the erosion processes considered are those of greatest importance to the field situation of concern; and • detailed description of both material and plot properties, to increase the potential for data to be applicable to a wider range of projects and investigations. Other important company procedures include: • For each project, the scientist or engineer responsible for analysing and reporting rainfall simulator data is present during the running of all field plots, as it is essential that they be aware of any specific conditions that may have developed when the plots were subjected

  3. Talons and beaks are viable but underutilized samples for detecting ...

    African Journals Online (AJOL)

    Talons and beaks are viable but underutilized samples for detecting organophosphorus and carbamate pesticide poisoning in raptors. Ngaio Richards, Irene Zorrilla, Joseph Lalah, Peter Otieno, Isabel Fernandez, Monica Calvino, Joaquin Garcia ...

  4. Commercial transport aircraft composite structures

    Science.gov (United States)

    Mccarty, J. E.

    1983-01-01

    The role that analysis plays in the development, production, and substantiation of aircraft structures is discussed. The types, elements, and applications of failure that are used and needed; the current application of analysis methods to commercial aircraft advanced composite structures, along with a projection of future needs; and some personal thoughts on analysis development goals and the elements of an approach to analysis development are discussed.

  5. Adaptation of commercial microscopes for advanced imaging applications

    Science.gov (United States)

    Brideau, Craig; Poon, Kelvin; Stys, Peter

    2015-03-01

    Today's commercially available microscopes offer a wide array of options to accommodate common imaging experiments. Occasionally, an experimental goal will require an unusual light source, filter, or even irregular sample that is not compatible with existing equipment. In these situations the ability to modify an existing microscopy platform with custom accessories can greatly extend its utility and allow for experiments not possible with stock equipment. Light source conditioning/manipulation such as polarization, beam diameter or even custom source filtering can easily be added with bulk components. Custom and after-market detectors can be added to external ports using optical construction hardware and adapters. This paper will present various examples of modifications carried out on commercial microscopes to address both atypical imaging modalities and research needs. Violet and near-ultraviolet source adaptation, custom detection filtering, and laser beam conditioning and control modifications will be demonstrated. The availability of basic `building block' parts will be discussed with respect to user safety, construction strategies, and ease of use.

  6. Technical and economic feasibility of thermal energy storage. Thermal energy storage application to the brick/ceramic industry. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Glenn, D.R.

    1976-10-01

    An initial project to study the technical and economic feasibility of thermal energy storage (TES) in the three major consumer markets, namely, the residential, commercial and industrial sectors is described. A major objective of the study was to identify viable TES applications from which a more concise study could be launched, leading to a conceptual design and in-depth validation of the TES energy impacts. This report documents one such program. The brick/ceramic industries commonly use periodic kilns which by their operating cycle require time-variant energy supply and consequently variable heat rejection. This application was one of the numerous TES opportunities that emerged from the first study, now available from the ERDA Technical Information Center, Oak Ridge, Tennessee, identified as Report No. COO-2558-1.

  7. Industrial Applications of High Average Power FELS

    CERN Document Server

    Shinn, Michelle D

    2005-01-01

    The use of lasers for material processing continues to expand, and the annual sales of such lasers exceeds $1 B (US). Large scale (many m2) processing of materials require the economical production of laser powers of the tens of kilowatts, and therefore are not yet commercial processes, although they have been demonstrated. The development of FELs based on superconducting RF (SRF) linac technology provides a scaleable path to laser outputs above 50 kW in the IR, rendering these applications economically viable, since the cost/photon drops as the output power increases. This approach also enables high average power ~ 1 kW output in the UV spectrum. Such FELs will provide quasi-cw (PRFs in the tens of MHz), of ultrafast (pulsewidth ~ 1 ps) output with very high beam quality. This talk will provide an overview of applications tests by our facility's users such as pulsed laser deposition, laser ablation, and laser surface modification, as well as present plans that will be tested with our upgraded FELs. These upg...

  8. Photovoltaic technologies for commercial power generation

    International Nuclear Information System (INIS)

    Carlson, D.E.

    1990-01-01

    Photovoltaic power generation is an attractive source of energy since it involves the direct conversion of sunlight into electricity with no moving parts and no pollution. Following the demonstration of the first solar cell 35 years ago at Bell Laboratories, a steady stream of scientific and commercial progress has led to a rapid increase in applications in recent years. The first commercial application of solar cells occurred more than 20 years ago when they were used to supply power for space satellites, and even today photovoltaic arrays are used to supply electricity for most satellites and space probes. This paper reviews the status of the various photovoltaic technologies as well as present applications. The prospects for both distributed and central station grid-connected systems are discussed. The paper concludes with a discussion of the institutional and political factors that will affect the introduction of grid-connected photovoltaic power systems

  9. Commercial and Industrial Wiring.

    Science.gov (United States)

    Kaltwasser, Stan; Flowers, Gary

    This module is the third in a series of three wiring publications, includes additional technical knowledge and applications required for job entry in the commercial and industrial wiring trade. The module contains 15 instructional units that cover the following topics: blueprint reading and load calculations; tools and equipment; service;…

  10. Gas-cooled reactor commercialization study. Interim report

    International Nuclear Information System (INIS)

    1977-01-01

    This report of the gas-cooled reactor commercialization study completes the technical and cost evaluation portions of this study contract. A final report in December will update the status of the incentive analyses and the issues of commercialization. This study was designed to bring together potential industry participants (utilities and suppliers) to evaluate the commercial potential of the HTGR-SC and to build channels of communication among the participating organizations at the same time that technical, economic and institutional issues were being evaluated. RAMCO, Inc., in suggesting and using this study approach, believes its application extends to any commercialization problem involving multi-party involvement in high capital, intensive, high risk energy technologies

  11. Accelerating the commercialization of university technologies for military healthcare applications: the role of the proof of concept process

    Science.gov (United States)

    Ochoa, Rosibel; DeLong, Hal; Kenyon, Jessica; Wilson, Eli

    2011-06-01

    The von Liebig Center for Entrepreneurism and Technology Advancement at UC San Diego (vonliebig.ucsd.edu) is focused on accelerating technology transfer and commercialization through programs and education on entrepreneurism. Technology Acceleration Projects (TAPs) that offer pre-venture grants and extensive mentoring on technology commercialization are a key component of its model which has been developed over the past ten years with the support of a grant from the von Liebig Foundation. In 2010, the von Liebig Entrepreneurism Center partnered with the U.S. Army Telemedicine and Advanced Technology Research Center (TATRC), to develop a regional model of Technology Acceleration Program initially focused on military research to be deployed across the nation to increase awareness of military medical needs and to accelerate the commercialization of novel technologies to treat the patient. Participants to these challenges are multi-disciplinary teams of graduate students and faculty in engineering, medicine and business representing universities and research institutes in a region, selected via a competitive process, who receive commercialization assistance and funding grants to support translation of their research discoveries into products or services. To validate this model, a pilot program focused on commercialization of wireless healthcare technologies targeting campuses in Southern California has been conducted with the additional support of Qualcomm, Inc. Three projects representing three different universities in Southern California were selected out of forty five applications from ten different universities and research institutes. Over the next twelve months, these teams will conduct proof of concept studies, technology development and preliminary market research to determine the commercial feasibility of their technologies. This first regional program will help build the needed tools and processes to adapt and replicate this model across other regions in the

  12. EVALUATION OF STATE-OF-THE-ART MANIPULATORS AND REQUIREMENTS FOR DOE ROBOTICS APPLICATIONS

    Energy Technology Data Exchange (ETDEWEB)

    BLACK, DEREK; GRUPINSKI, STEPHEN

    1998-10-08

    This report provides an overview of applications within the DOE complex which could benefit from the use of modular robotics technology during remediation operations. Each application area contains one or more specific tasks which are presently conducted by humans under hazardous conditions or which are deemed highly impractical, or are altogether impossible without automation. Five major areas were investigated for specific needs with respect to automation. Information was collected on Mixed Waste Operations, Contaminant Automated Analysis, Tanks, Decontamination and Dismantlement and Automated Plutonium Processing. During this investigation, information was gathered from available literature, telephone interviews with informed personnel and on-site visits. This data serves to provide design requirements and guidelines for the design of a family of modular actuators, which will be used to construct manipulators suited to each task. In addition, a survey of existing modular manipulator designs is presented. This survey addresses modular manipulators developed inside government labs and in universities for such applications as space exploration or controls research. It also addresses efforts at commercially viable industrial manipulators which have been built. This survey of robotic systems provides the reader with a glimpse into what technology currently exists in the way of modular manipulator automation and, to a degree, where this technology may be applicable or, more often, where these systems are unsuited to EM applications. From the information gathered during this study, it is possible to sufficiently define the requirements of one manipulator system which can be used to conduct automated transfer operations within Plutonium gloveboxes. This manipulator will be constructed from ARM Automation actuator modules and will provide this application with a viable option for automation within these gloveboxes. The design issues surrounding this manipulator and its

  13. Storage mite contamination of commercial dry dog food in south-eastern Australia.

    Science.gov (United States)

    Hibberson, C E; Vogelnest, L J

    2014-06-01

    To evaluate contamination of unopened and opened stored sources of commercial dry dog food by viable storage mites. Prospective laboratory and field study. Samples were collected from nine brands of previously unopened bags (new bags) of dry food and 20 field sources of stored dry food in homes in Sydney and Canberra, Australia. All samples were initially examined for the presence of mites using a stereo-binocular microscope and then placed in separate filter-paper-sealed containers. Field samples were incubated at an average temperature of 29°C and 78% relative humidity (RH) for 5 weeks and then at average 26°C/83% RH for 8 weeks. Paired new-bag samples were stored under room conditions (average 23°C/47% RH) and controlled incubator conditions (average 26°C/80% RH) for 6 weeks. All samples were thoroughly examined for mites, mite eggs and visible mould once weekly using a stereo-binocular microscope. Storage mites were not visualised in any of the field samples or in new-bag samples stored at room temperature. Storage mites, identified as Tyrophagus putrescentiae, were visualised in increasing numbers in seven of nine new-bag samples after incubation, with first mites and then eggs evident after 3 weeks of incubation. We confirmed the presence of viable storage mites in a range of previously unopened commercial dry dog foods in Australia and confirmed the possibility of heavy storage mite contamination for dry food stored under conditions of moderate temperature and high humidity. These findings have relevance to storage mite and/or dust mite sensitivity in canine atopic dermatitis. © 2014 Australian Veterinary Association.

  14. Generic requirements specification for qualifying a commercially available PLC for safety-related applications in nuclear power plants. Final report

    International Nuclear Information System (INIS)

    Ostenso, A.; May, R.

    1996-12-01

    This is a specification for qualifying a commercially available PLC for application to safety systems in nuclear power plants. The specifications are suitable for evaluating a particular PLC product line as a platform for safety-related applications, establishing a suitable qualification test program, and confirming that the manufacturer has a quality assurance program that is adequate for safety-related applications or is sufficiently complete that, with a reasonable set of compensatory actions, it can be brought into conformance. The specification includes requirements for: (1) quality assurance measures applied to the qualification activities, (2) documentation to support the qualification, and (3) documentation to provide the information needed for applying the qualified PLC platform to a specific application. The specifications are designed to encompass a broad range of safety applications; however, qualifying a particular platform for a different range of applications can be accomplished by appropriate adjustments to the requirements

  15. Solar System constraints on a cosmologically viable f(R) theory

    Energy Technology Data Exchange (ETDEWEB)

    Bisabr, Yousef, E-mail: y-bisabr@srttu.ed [Department of Physics, Shahid Rajaee Teacher Training University, Lavizan, Tehran 16788 (Iran, Islamic Republic of)

    2010-01-18

    Recently, a model f(R) theory is proposed (Miranda et al. (2009)) which is cosmologically viable and distinguishable from LAMBDACDM. We use chameleon mechanism to investigate viability of the model in terms of Solar System experiments.

  16. Evaluation of Commercial Agrochemicals as New Tools for Malaria Vector Control.

    Science.gov (United States)

    Hoppé, Mark; Hueter, Ottmar F; Bywater, Andy; Wege, Philip; Maienfisch, Peter

    2016-10-01

    Malaria is a vector-borne and life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. The vector control insecticide market represents a small fraction of the crop protection market and is estimated to be valued at up to $500 million at the active ingredient level. Insecticide resistance towards the current WHOPES-approved products urgently requires the development of new tools to protect communities against the transmission of malaria. The evaluation of commercial products for malaria vector control is a viable and cost effective strategy to identify new malaria vector control products. Several examples of such spin-offs from crop protection insecticides are already evidencing the success of this strategy, namely pirimiphos-methyl for indoor residual sprays and spinosad, diflubenzuron, novaluron, and pyriproxifen for mosquito larvae control, a supplementary technology for control of malaria vectors. In our study the adulticidal activities of 81 insecticides representing 23 insecticidal modes of action classes, 34 fungicides from 6 fungicidal mode of action classes and 15 herbicides from 2 herbicidal modes of action classes were tested in a newly developed screening system. WHOPES approved insecticides for malaria vector control consistently caused 80-100% mortality of adult Anopheles stephensi at application rates between 0.2 and 20 mg active ingradient (AI) litre -1 . Chlorfenapyr, fipronil, carbosulfan and endosulfan showed the expected good activity. Four new insecticides and three fungicides with promising activity against adult mosquitoes were identified, namely the insecticides acetamiprid, thiamethoxam, thiocyclam and metaflumizone and the fungicides diflumetorin, picoxystrobin, and fluazinam. Some of these compounds certainly deserve to be further evaluated for malaria vector control. This is the first report describing good activity of commercial fungicides against malaria

  17. Total dose hardness of a commercial SiGe BiCMOS technology

    International Nuclear Information System (INIS)

    Van Vonno, N.; Lucas, R.; Thornberry, D.

    1999-01-01

    Over the past decade SiGe HBT technology has progress from the laboratory to actual commercial applications. When integrated into a BiMOS process, this technology has applications in low-cost space systems. In this paper, we report results of total dose testing of a SiGe/CMOS process accessible through a commercial foundry. (authors)

  18. Solar System constraints on a cosmologically viable f(R) theory

    International Nuclear Information System (INIS)

    Bisabr, Yousef

    2010-01-01

    Recently, a model f(R) theory is proposed (Miranda et al. (2009)) which is cosmologically viable and distinguishable from ΛCDM. We use chameleon mechanism to investigate viability of the model in terms of Solar System experiments.

  19. 48 CFR 1852.227-86 - Commercial computer software-Licensing.

    Science.gov (United States)

    2010-10-01

    .../contractor proposes its standard commercial software license, those applicable portions thereof consistent... its standard commercial software license until after this purchase order/contract has been issued, or at or after the time the computer software is delivered, such license shall nevertheless be deemed...

  20. 46 CFR 105.05-1 - Commercial fishing vessels dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Commercial fishing vessels dispensing petroleum products... MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Application § 105.05-1 Commercial fishing vessels dispensing petroleum products. (a) The provisions of this part, with the exception of...

  1. Study on commercial FBR concepts by combining innovative technologies

    International Nuclear Information System (INIS)

    Miura, M.; Inagaki, T.; Kuroha, M.; Hida, T.

    1992-01-01

    A study was conducted on future prospects of FBR commercialization. Targets of further improving safety and economy were set to make commercial power plants that would be superior to future LWRs. Promising innovative technologies studied domestically and overseas were extracted by evaluating prospects for commercialization, effect, and plant applicability. Several commercial plants were conceptualized by introducing such technology to large-scale and oxide-fuel reactors. Estimates of construction cost, etc., proved that the targets could be achieved. A concept of long-term technological development was synthesized. (author)

  2. Technology data characterizing water heating in commercial buildings: Application to end-use forecasting

    Energy Technology Data Exchange (ETDEWEB)

    Sezgen, O.; Koomey, J.G.

    1995-12-01

    Commercial-sector conservation analyses have traditionally focused on lighting and space conditioning because of their relatively-large shares of electricity and fuel consumption in commercial buildings. In this report we focus on water heating, which is one of the neglected end uses in the commercial sector. The share of the water-heating end use in commercial-sector electricity consumption is 3%, which corresponds to 0.3 quadrillion Btu (quads) of primary energy consumption. Water heating accounts for 15% of commercial-sector fuel use, which corresponds to 1.6 quads of primary energy consumption. Although smaller in absolute size than the savings associated with lighting and space conditioning, the potential cost-effective energy savings from water heaters are large enough in percentage terms to warrant closer attention. In addition, water heating is much more important in particular building types than in the commercial sector as a whole. Fuel consumption for water heating is highest in lodging establishments, hospitals, and restaurants (0.27, 0.22, and 0.19 quads, respectively); water heating`s share of fuel consumption for these building types is 35%, 18% and 32%, respectively. At the Lawrence Berkeley National Laboratory, we have developed and refined a base-year data set characterizing water heating technologies in commercial buildings as well as a modeling framework. We present the data and modeling framework in this report. The present commercial floorstock is characterized in terms of water heating requirements and technology saturations. Cost-efficiency data for water heating technologies are also developed. These data are intended to support models used for forecasting energy use of water heating in the commercial sector.

  3. A viable real estate economy with disruption and blockchain

    NARCIS (Netherlands)

    Veuger, Jan

    2017-01-01

    Two titles in one cover. On page 56-112 there's the English version of the book: 'A viable real estate economy with disruption and blockchain. Does real estate still have the value that it had, or is the valuation of real estate going to change due to surprising products and services, innovative

  4. Promoting Women Participation in Aquaculture as a Viable Tool for ...

    African Journals Online (AJOL)

    Promoting Women Participation in Aquaculture as a Viable Tool for Poverty Alleviation in the Rural Areas of Nigeria. ... Open Access DOWNLOAD FULL TEXT ... a source of income, also the paper focus on the roles of women in aquaculture, ...

  5. Performance evaluation of a commercially available heat flow calorimeter and applicability assessment for safeguarding special nuclear materials

    International Nuclear Information System (INIS)

    Bracken, D.S.; Biddle, R.; Rudy, C.

    1998-01-01

    The performance characteristics of a commercially available heat-flow calorimeter will be presented. The heat-flow sensors within the calorimeter are based on thermopile technology with a vendor-quoted sensitivity of 150 microV/mW. The calorimeter is a full-twin design to compensate for ambient temperature fluctuations. The efficacy of temperature fluctuation compensations will also be detailed. Finally, an assessment of design applicability to special nuclear materials control and accountability and safeguarding will be presented

  6. Business analysis: The commercial mission of the International Asteroid Mission

    Science.gov (United States)

    The mission of the International Asteroid Mission (IAM) is providing asteroidal resources to support activities in space. The short term goal is to initiate IAM by mining a near-Earth, hydrous carbonaceous chondrite asteroid to service the nearer-term market of providing cryogenic rocket fuel in low lunar orbit (LLO). The IAM will develop and contract for the building of the transportation vehicles and equipment necessary for this undertaking. The long-term goal is to expand operations by exploiting asteroids in other manners, as these options become commercially viable. The primary business issues are what revenue can be generated from the baseline mission, how much will the mission cost, and how funding for this mission can be raised. These issues are addressed.

  7. Development of a commercial enzymes system for lignocellulosic biomass saccharification

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Manoj

    2012-12-20

    DSM Innovation Inc., in its four year effort was able to evaluate and develop its in-house DSM fungal cellulolytic enzymes system to reach enzyme efficiency mandates set by DoE Biomass program MYPP goals. DSM enzyme cocktail is uniquely active at high temperature and acidic pH, offering many benefits and product differentiation in 2G bioethanol production. Under this project, strain and process development, ratio optimization of enzymes, protein and genetic engineering has led to multitudes of improvement in productivity and efficiency making development of a commercial enzyme system for lignocellulosic biomass saccharification viable. DSM is continuing further improvement by additional biodiversity screening, protein engineering and overexpression of enzymes to continue to further lower the cost of enzymes for saccharification of biomass.

  8. Thermal comfort in commercial kitchens (RP-1469)

    DEFF Research Database (Denmark)

    Simone, Angela; Olesen, Bjarne W.; Stoops, John L.

    2013-01-01

    The indoor climate in commercial kitchens is often unsatisfactory, and working conditions can have a significant effect on employees’ comfort and productivity. The type of establishment (fast food, casual, etc.) and climatic zone can influence thermal conditions in the kitchens. Moreover, the size...... and arrangement of the kitchen zones, appliances, etc., further complicate an evaluation of the indoor thermal environment in commercial kitchens. In general, comfort criteria are stipulated in international standards (e.g., ASHRAE 55 or ISO EN 7730), but are these standardized methods applicable...... dissatisfied (PMV/PPD) index is not directly appropriate for all thermal conditions in commercial kitchens....

  9. Entry of Vibrio harveyi and Vibrio fischeri into the viable but nonculturable state.

    Science.gov (United States)

    Ramaiah, N; Ravel, J; Straube, W L; Hill, R T; Colwell, R R

    2002-01-01

    Physiological responses of marine luminous bacteria, Vibrio harveyi (ATCC 14216) and V. fischeri (UM1373) to nutrient-limited normal strength (35 ppt iso-osmolarity) and low (10 ppt hypo-osmolarity) salinity conditions were determined. Plate counts, direct viable counts, actively respiring cell counts, nucleoid-containing cell counts, and total counts were determined. Vibrio harveyi incubated at 22 degrees C in nutrient-limited artificial seawater (ASW) became nonculturable after approximately 62 and 45 d in microcosms of 35 ppt and 10 ppt ASW, respectively. In contrast, V. fischeri became nonculturable at approximately 55 and 31 d in similar microcosms. Recovery of both culturability and luminescence of cells in the viable but nonculturable state was achieved by addition of nutrient broth or nutrient broth supplemented with a carbon source, including luminescence-stimulating compounds. Temperature upshift from 22 degrees C to 30 degrees C or 37 degrees C did not result in recovery from nonculturability. The study confirms entry of V. harveyi and V. fischeri into the viable but nonculturable state under low-nutrient conditions and demonstrates nutrient-dependent resuscitation from this state. This study confirms loss of luminescence of V. harveyi and V. fischeri on entry into the viable but nonculturable state and suggests that enumeration of luminescent cells in water samples may be a rapid method to deduce the nutrient status of a water sample.

  10. Progress report of the Radiation Technology and Industrial Applications Section, Isotope Group for the period ending August 1977

    International Nuclear Information System (INIS)

    Naik, A.D.; Roy, A.N.; Majali, A.B.

    1977-01-01

    The activities of the Radiation Technology and Industrial Applications Section of the Bhabha Atomic Research Centre, Bombay, for the period ending August 1977 are reported. Major highlights are: (1) completion of studies and design engineering for an economic scale cobalt-60 based irradiator for the radiation sterilisation of medical products, (2) taking up the work of setting up the cobalt-60 irradiation facilities for sources up to 300,000 Ci level, (3) development of radiation processed wood-polymer composite and practical demonstration of its superiority for application in industries - a cobalt-60 facility specifically for this purpose is being installed, (4) development of a commercially viable design of a smoke alarm system based on radioisotopes and (5) production and supply of irradiation units such as gamma chambers, radiography cameras, etc. (M.G.B.)

  11. University of Utah, Energy Commercialization Center

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, James [Univ. of Utah, Salt Lake City, UT (United States)

    2014-01-17

    During the Energy Commercialization Center’s (ECC) three years in operation, the only thing constant was change. The world of commercialization and cleantech evolved significantly during the time the ECC was formed and operating, including: the availability of cleantech funding lessoned, the growth of incubators and accelerators skyrocketed, the State of Utah created an office dedicated to energy development, the University of Utah was both praised and criticized for its success in commercialization, and the Federal government temporarily shut down. During the three-year grant there were three principle investigators on the grant, as well as three directors for the University’s Commercialization Office. Change can be hard for an organization,but as we instruct the companies we support, “Fail fast and fail often, because it is the fastest path to success.” Although there were some unanticipated challenges along the way, the local ecosystem is stronger because of the ECC’s efforts. Perhaps the greatest lesson learned was the importance of aligned incentives between key stakeholders in the commercialization process and the need for resources at the company and individual entrepreneur levels. The universities have systems and incentives to commercialize technologies, but creating value and companies generally rest with the individuals and entrepreneurs. Unfortunately the ECC was unable to create a viable mechanism to transfer the commercialization process that successfully aligned incentives and achieve a more effective ecosystem within the Rocky Mountain West. However, the ECC was successful in adding value to the individual ecosystems, and connecting national resources to regional and local needs. Regarding the ECC’s effectiveness in developing a cleantech commercialization ecosystem, initial inroads and relationships were established with key stakeholders. However, incentives, perceived or real competition, differences in commercialization processes, and

  12. Commercialization scenarios of polymer electrolyte membrane fuel cell applications for stationary power generation in the United States by the year 2015

    Science.gov (United States)

    Millett, Stephen; Mahadevan, Kathya

    Battelle is identifying the most likely markets and economic impacts of stationary polymer electrolyte membrane (PEM) fuel cells in the range of 1-250 kW in the U.S. by the year 2015. For this task, Battelle is using the Interactive Future Simulations (IFS™), an analytical modeling and forecasting tool that uses expert judgment, trend analysis, and cross-impact analysis methods to generate most likely future conditions for PEM fuel cell applications, market acceptance, commercial viability, and economic impacts. The cross-impact model contains 28 descriptors including commercial and technological advances in both polymer electrolyte membrane (PEM) fuel cells and fossil fuel technologies, sources of hydrogen, investments, public policy, environmental regulation, value to consumers, commercialization leadership, modes of generation, and the reliability and prices of grid electricity. One likely scenario to the year 2015 is that the PEM fuel cells will be limited to commercial and industrial customers in the range of 50-200 kW with a market size less than US$ 5 billion a year.

  13. Cybernetically sound organizational structures II: Relating de Sitter's design theory to Beer's viable system model

    NARCIS (Netherlands)

    Achterbergh, J.M.I.M.; Vriens, D.J.

    2011-01-01

    - Purpose – The purpose of this paper is to show how the viable system model (VSM) and de Sitter's design theory can complement each other in the context of the diagnosis and design of viable organizations. - Design/methodology/approach – Key concepts from Beer's model and de Sitter's design theory

  14. Commercial Security on the Internet.

    Science.gov (United States)

    Liddy, Carrie

    1996-01-01

    Discusses commercial security on the Internet and explains public key technology as successfully melding the conflicting requirements of openness for practical business applications and isolation and confidentiality for protection of data. Examples of public key value-added products are described, including encryption, digital signature and…

  15. Introduce of Viable But Nonculturable Bacteria

    Directory of Open Access Journals (Sweden)

    Mehdi Hassanshahian

    2008-03-01

    Full Text Available Viable-But-Nonculturable-State (VBNC is the condition in which bacteria fail to grow on their routine bacteriological media where they would normally grow and develop into colonies, but are still alive and capable of renewed metabolic activity. VBNC state is useful for evaluating public health and for ascertaining the sterility of drinking water, pharmaceuticals, and foodstuff. A number of bacteria, mostly pathogenic to humans, have been proved to enter into this state in response to natural stresses such as starvation, incubation out of optimum growth temperature, increased osmotic pressure, etc. Once in the VBNC state, they undergo various physiological, structural, and genetic alterations. These alterations result in reduced cell size, conversion from bacilli to coccid, thickened cell walls, and peptidoglycan gaining many cross links. Metabolic changes also occur that include reductions in growth, nutrient transport, and respiratory rate; biosynthesis of new protein, and ATP remaining at a constant level. It has been shown that in the VBNC state, some pathogens conserve their virulence properties. Gene expression continues in the VBNC cell. Nucleic acids remain intact in the early VBNC phase but they gradually undergo degradation with prolonged VBNC. Cytological methods such as direct viable count and reduction of tetrazolium salts, and molecular methods such as reverse transcription polymerase chain reaction and green fluorescent protein have been used for the study of VBNC. Resuscitation from VBNC state starts when the inducing factor(s is/are lifted. Factors that help the resuscitation of VBNC bacteria include addition of certain nutrients and chemicals, introduction of a few culturable cells into the VBNC cell population, and passage through the animal host. As virulence properties are sustained during the VBNC phase, special care must be paid when evaluating sterility of drinking water.

  16. Early high-Tc commercial activity

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    The high temperature superconductors have already begun to generate the first stirrings of commercial activity. Companies that supply instruments and chemicals to researchers have enjoyed increased business. At least one company has begun to supply educational materials. Venture capital firms have invested about $15 million in startups to capitalize on developments in high-field applications, superconducting electronics, and magnetic shielding. Consulting firms are gathering and selling market research information. And the federal government is studying the question of how to cooperate with American companies to commercialize the research taking place in the national laboratories. This article discusses these issues

  17. Private Astronaut Training Prepares Commercial Crews of Tomorrow

    Science.gov (United States)

    2015-01-01

    A new company that includes a handful of former NASA personnel is already taking applications for the first comprehensive commercial astronaut training approved by the Federal Aviation Administration. Waypoint 2 Space, located at Johnson Space Center, hopes to draw space tourists and enthusiasts and future commercial crewmembers with first-hand NASA know-how, as well as agency training technology.

  18. NRC research on the application of advanced I and C technology to commercial nuclear power plants

    International Nuclear Information System (INIS)

    Gollei, K.R.; Hon, A.L.

    1983-01-01

    The operational safety and efficiency of commercial nuclear power plants (NPP's) could possibly be enhanced by utilizing advanced instrumentation and control technology developed by other industries. The NRC is interested in learning about new I and C technology that probably will or could be applied to new or existing plants. This would enable the NRC to be better prepared to evaluate the application without undue delays. It would also help identify any appropriate changes in NRC regulations or guidance necessary to facilitate the application of advanced IandC technology to NPP's. The NRC has initiated a project to work cooperatively with the advanced technology industry, power industry, EPRI, and technical organizations such as ISA toward this goal. This paper describes the objectives and plans of this cooperative effort. It summarizes the highlights of some of the advanced technology already being evaluated by NRC such as microprocessor applications, instruments to detect inadequate core cooling and other two-phase flow measurements, reactor noise surveillance and diagnostic techniques. This paper also suggests potential candidates for consideration such as utilization of advanced instruments for LOCA experiments. It also identifies some of the potential challenges facing the application of advanced technology to NPP's. It concludes that close cooperation between NRC and industry is essential for the success of such applications

  19. C in CS1: Snags and Viable Solution

    Directory of Open Access Journals (Sweden)

    Shumail Naveed

    2018-01-01

    Full Text Available Programming is one of the career rewarding skills; however, learning programming skill is extremely hard and arduous as supported by several studies. The first programming language has an everlasting impact on the programmer’s program’s development abilities. In most of the universities the imperative paradigm is used for introductory programming courses and generally C language is used as a base language of a first programming course. The C language is a leading programming language and extensively utilized for commercial applications. The majority of the programming languages are highly motivated from the C language, yet its intrinsic complexities and non-pedagogic origin evidently makes it hard and a complex choice for a first programming course. This paper proposed a rational and realizable solution that can make a C language a suitable choice for a first the course of programming.

  20. C in CS1: Snags and viable solution

    International Nuclear Information System (INIS)

    Naveed, S.; Sarim, M.; Nadeem, A.

    2018-01-01

    Programming is one of the career rewarding skills; however, learning programming skill is extremely hard and arduous as supported by several studies. The first programming language has an everlasting impact on the programmer’s program’s development abilities. In most of the universities the imperative paradigm is used for introductory programming courses and generally C language is used as a base language of a first programming course. The C language is a leading programming language and extensively utilized for commercial applications. The majority of the programming languages are highly motivated from the C language, yet its intrinsic complexities and non-pedagogic origin evidently makes it hard and a complex choice for a first programming course. This paper proposed a rational and realizable solution that can make a C language a suitable choice for a first the course of programming. (author)

  1. Separation of viable lactic acid bacteria from fermented milk

    Directory of Open Access Journals (Sweden)

    Tomohiko Nishino

    2018-04-01

    Full Text Available Probiotics are live microorganisms that provide health benefits to humans. Some lactic acid bacteria (LAB are probiotic organisms used in the production of fermented foods, such as yogurt, cheese, and pickles. Given their widespread consumption, it is important to understand the physiological state of LAB in foods such as yogurt. However, this analysis is complicated, as it is difficult to separate the LAB from milk components such as solid curds, which prevent cell separation by dilution or centrifugation. In this study, we successfully separated viable LAB from yogurt by density gradient centrifugation. The recovery rate was >90 %, and separation was performed until the stationary phase. Recovered cells were observable by microscopy, meaning that morphological changes and cell viability could be directly detected at the single-cell level. The results indicate that viable LAB can be easily purified from fermented milk. We expect that this method will be a useful tool for the analysis of various aspects of probiotic cells, including their enzyme activity and protein expression. Keywords: Food analysis, Microbiology

  2. Thermal energy storage for cooling of commercial buildings

    Energy Technology Data Exchange (ETDEWEB)

    Akbari, H. (Lawrence Berkeley Lab., CA (USA)); Mertol, A. (Science Applications International Corp., Los Altos, CA (USA))

    1988-07-01

    The storage of coolness'' has been in use in limited applications for more than a half century. Recently, because of high electricity costs during utilities' peak power periods, thermal storage for cooling has become a prime target for load management strategies. Systems with cool storage shift all or part of the electricity requirement from peak to off-peak hours to take advantage of reduced demand charges and/or off-peak rates. Thermal storage technology applies equally to industrial, commercial, and residential sectors. In the industrial sector, because of the lack of economic incentives and the custom design required for each application, the penetration of this technology has been limited to a few industries. The penetration rate in the residential sector has been also very limited due to the absence of economic incentives, sizing problems, and the lack of compact packaged systems. To date, the most promising applications of these systems, therefore, appear to be for commercial cooling. In this report, the current and potential use of thermal energy storage systems for cooling commercial buildings is investigated. In addition, a general overview of the technology is presented and the applicability and cost-effectiveness of this technology for developed and developing countries are discussed. 28 refs., 12 figs., 1 tab.

  3. Preliminary applied study of assessment ischemic/viable myocardium by 99Tcm-HL91

    International Nuclear Information System (INIS)

    Liu Gang; Wu Hua

    2004-01-01

    Objective: To investigate the representation of 99 Tc m -HL91 in the ischemic myocardium, evaluate the diagnosis value of 99 Tc m -HL91 on hypoxic but viable myocardium. Methods: Six patients with cardiac infarction all underwent 99 Tc m -MIBI SPECT and 99 Tc m -HL91 SPECT. Average radioactivity of ischemic area and normal area were respectively obtained by ROI (2 x 2 pixels) on heart minor axis of images, And the radioactivity ratios of target (ischemic area)-to-non target(normal area)were calculated. Results: In image of 99 Tc m -HL91 SPECT, two patients who's radioactivity coloboma of 99 Tc m -MIBI image could be filled with 99 Tc m -HL91, four patients were not caught sight of obvious filling up. Conclusion 99 Tc m -HL91 can be selectively uptaken by ischemic and hypoxic but viable myocardium. it combination of 99 Tc m -MIBI SPECT may be good for accurate diagnosis and differentiation of viable myocardium. (authors)

  4. Studies on the comparison of pollen morphology and viability of four naturally distributed and commercial varieties of anemone coronaria L

    International Nuclear Information System (INIS)

    Candan, F.

    2015-01-01

    The present study presents a comparison of the pollen morphology and viability of naturally distributed four varieties of Anemone coronaria L. These are A. coronaria var. coccinea (Jord.) Burn, A. coronaria var. rosea (Hanry) Batt, A. coronaria var. cyanea, A. coronaria var. alba Goaty and Pens) and its commercial cultivars. The four varieties were collected from areas near the road side along the Kirkagac-Soma highway in the State of Manisa. The commercial cultivars were obtained from the commercial flower growers in the Urla region of zmir. Pollen viability levels decreased in all commercial cultivars of A. coronaria. The highest reduction in pollen viability was recorded in A. coronaria pink cultivars of de Caen group. The general pollen type is prolate spheroidal in all pure forms, but there are some pollen morphological features which were not observed in the natural ones, although encountered in all commercial cultivars. On the other hand, various non-viable pollen types like wrinkled pollens, with abnormally shaped pollens or pollinia were found in the commercial cultivars. It was concluded that pesticides used to produce more flowers with rapid growth are the major cause for his reduction. Another reason could be the use of tetraploid F1 hybrids of A. coronaria cultivars of de Caen group as commercial samples. (author)

  5. Detection of viable but non-culturable Escherichia coli O157:H7 by PCR in combination with propidium monoazide.

    Science.gov (United States)

    Zhong, Junliang; Zhao, Xihong

    2018-01-01

    The aim of this study was to evaluate the applicability of the conventional PCR detection method combined with propidium monoazide (PMA) treatment for the detection of viable but non-culturable (VBNC) state Escherichia coli O157:H7 in ground beef meatballs. Under low temperature, E. coli O157:H7 cells were induced into the VBNC state in ground beef meatballs at - 20 °C after 152 days. The optimal PMA concentration of 5 µg/mL was obtained in beef meatball samples, which could completely inhibit the DNA amplification on dead cells (10 6  cells/mL) but with no inhibition on viable cells. The established PMA-PCR assay revealed that the VBNC counts exceeded 10 7  CFU/mL in artificial contamination beef samples, which could be used for semi-quantitative detection of VBNC cells in beef meatball samples. This study indicated that the PMA-PCR assay might be a potential method for detection of VBNC state E . coli O157:H7 cells in food products.

  6. Commercial Application of a Photovoltaic Concentrator system. Phase I. Final report, 1 June 1978-28 February 1979

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, D.J.; Anderson, E.R.; Bardwell, K.M.

    1980-04-01

    This report documents the design and analysis of the BDM CAPVC (Commercial Application of a Photovoltaic Concentrator) system. The preliminary design, prototype test and evaluation, system analysis, and final design of a large-scale concentrating photovoltaic system are described. The application is on an attractive new office building which represents a large potential market. The photovoltaic concentrating array is a roof-mounted, single-axis linear parabolic trough, using single crystalline silicon photovoltaic cells. A total of 6720 square feet of aperture is focussed on 13,944 PV cells. The photovoltaic system operates in parallel with the local utility in an augmentary loadsharing operating mode. The array is actively cooled and the thermal energy utilized for building heat during winter months. (WHK)

  7. New Digital Metal-Oxide (MOx Sensor Platform

    Directory of Open Access Journals (Sweden)

    Daniel Rüffer

    2018-03-01

    Full Text Available The application of metal oxide gas sensors in Internet of Things (IoT devices and mobile platforms like wearables and mobile phones offers new opportunities for sensing applications. Metal-oxide (MOx sensors are promising candidates for such applications, thanks to the scientific progresses achieved in recent years. For the widespread application of MOx sensors, viable commercial offerings are required. In this publication, the authors show that with the new Sensirion Gas Platform (SGP a milestone in the commercial application of MOx technology has been reached. The architecture of the new platform and its performance in selected applications are presented.

  8. Benchmarking Commercial Conformer Ensemble Generators.

    Science.gov (United States)

    Friedrich, Nils-Ole; de Bruyn Kops, Christina; Flachsenberg, Florian; Sommer, Kai; Rarey, Matthias; Kirchmair, Johannes

    2017-11-27

    We assess and compare the performance of eight commercial conformer ensemble generators (ConfGen, ConfGenX, cxcalc, iCon, MOE LowModeMD, MOE Stochastic, MOE Conformation Import, and OMEGA) and one leading free algorithm, the distance geometry algorithm implemented in RDKit. The comparative study is based on a new version of the Platinum Diverse Dataset, a high-quality benchmarking dataset of 2859 protein-bound ligand conformations extracted from the PDB. Differences in the performance of commercial algorithms are much smaller than those observed for free algorithms in our previous study (J. Chem. Inf. 2017, 57, 529-539). For commercial algorithms, the median minimum root-mean-square deviations measured between protein-bound ligand conformations and ensembles of a maximum of 250 conformers are between 0.46 and 0.61 Å. Commercial conformer ensemble generators are characterized by their high robustness, with at least 99% of all input molecules successfully processed and few or even no substantial geometrical errors detectable in their output conformations. The RDKit distance geometry algorithm (with minimization enabled) appears to be a good free alternative since its performance is comparable to that of the midranked commercial algorithms. Based on a statistical analysis, we elaborate on which algorithms to use and how to parametrize them for best performance in different application scenarios.

  9. Weldability, machinability and surfacing of commercial duplex stainless steel AISI2205 for marine applications - A recent review.

    Science.gov (United States)

    Vinoth Jebaraj, A; Ajaykumar, L; Deepak, C R; Aditya, K V V

    2017-05-01

    In the present review, attempts have been made to analyze the metallurgical, mechanical, and corrosion properties of commercial marine alloy duplex stainless steel AISI 2205 with special reference to its weldability, machinability, and surfacing. In the first part, effects of various fusion and solid-state welding processes on joining DSS 2205 with similar and dissimilar metals are addressed. Microstructural changes during the weld cooling cycle such as austenite reformation, partitioning of alloying elements, HAZ transformations, and the intermetallic precipitations are analyzed and compared with the different welding techniques. In the second part, machinability of DSS 2205 is compared with the commercial ASS grades in order to justify the quality of machining. In the third part, the importance of surface quality in a marine exposure is emphasized and the enhancement of surface properties through peening techniques is highlighted. The research gaps and inferences highlighted in this review will be more useful for the fabrications involved in the marine applications.

  10. Succinic Acid: Technology Development and Commercialization

    Directory of Open Access Journals (Sweden)

    Nhuan P. Nghiem

    2017-06-01

    Full Text Available Succinic acid is a precursor of many important, large-volume industrial chemicals and consumer products. It was once common knowledge that many ruminant microorganisms accumulated succinic acid under anaerobic conditions. However, it was not until the discovery of Anaerobiospirillum succiniciproducens at the Michigan Biotechnology Institute (MBI, which was capable of producing succinic acid up to about 50 g/L under optimum conditions, that the commercial feasibility of producing the compound by biological processes was realized. Other microbial strains capable of producing succinic acid to high final concentrations subsequently were isolated and engineered, followed by development of fermentation processes for their uses. Processes for recovery and purification of succinic acid from fermentation broths were simultaneously established along with new applications of succinic acid, e.g., production of biodegradable deicing compounds and solvents. Several technologies for the fermentation-based production of succinic acid and the subsequent conversion to useful products are currently commercialized. This review gives a summary of the development of microbial strains, their fermentation, and the importance of the down-stream recovery and purification efforts to suit various applications in the context of their current commercialization status for biologically derived succinic acid.

  11. Studies on chlorophyll and viable mutations in green gram (Vigna radiata L. Wilczek) II: Response to mutagen

    Energy Technology Data Exchange (ETDEWEB)

    Krishnaswami, S; Rathinam, M [Tamil Nadu Agricultural Univ., Coimbatore (India). Dept. of Agricultural Botany

    1980-09-01

    The frequency and spectrum of chlorophyll and viable mutations in relation to type and dose of mutagen and cluster progenies were studied in four green gram cultivars viz., Kopergaon, Pusa Baisakhi, L. 24/2 and Sel. 122 subjected to two levels of EMS and gamma irradiation, severally and in conjunction. While chlorophyll mutations did not vary with the mutagen dose, viable mutations exhibited a direct relationship. Combinations of the mutagens were more effective in mutation induction. While no difference was manifested between the cluster families in respect of chlorophyll mutations, progenies of the second cluster recorded less viable mutations than either the first or the third. Viridis and xanthoviridis among chlorophyll mutations, and those affecting plant duration and stature among viable were more predominant.

  12. Commercialization of the polyethylene macroencapsulation process

    International Nuclear Information System (INIS)

    Lageraaen, P.R.; Kalb, P.D.; Hellstrom, G.W.; Vance, J.K.

    1998-01-01

    With support from the US Department of Energy Office of Science and Technology (DOE OST) and assistance from Brookhaven National Laboratory (BNL), Envirocare of Utah, Inc. (Envirocare) is commercializing the polyethylene macroencapsulation process. Envirocare, currently the only commercially licensed mixed waste disposal facility in the US, will initially demonstrate the process by treating and disposing up to 227,000 kg (500,000 lbs) of radioactively contaminated lead. This waste, considered mixed due to both radioactive and hazardous constituents, is currently being stored at various sites throughout the DOE complex. Following this initial work for DOE, the process will be available for the treatment of other applicable wastes. Throughout commercialization of this process, BNL has provided Envirocare with technical support for engineering and permitting

  13. Note: Commercial SQUID magnetometer-compatible NMR probe and its application for studying a quantum magnet.

    Science.gov (United States)

    Vennemann, T; Jeong, M; Yoon, D; Magrez, A; Berger, H; Yang, L; Živković, I; Babkevich, P; Rønnow, H M

    2018-04-01

    We present a compact nuclear magnetic resonance (NMR) probe which is compatible with a magnet of a commercial superconducting quantum interference device magnetometer and demonstrate its application to the study of a quantum magnet. We employ trimmer chip capacitors to construct an NMR tank circuit for low temperature measurements. Using a magnetic insulator MoOPO 4 with S = 1/2 (Mo 5+ ) as an example, we show that the T-dependence of the circuit is weak enough to allow the ligand-ion NMR study of magnetic systems. Our 31 P NMR results are compatible with previous bulk susceptibility and neutron scattering experiments and furthermore reveal unconventional spin dynamics.

  14. Radiation tolerance study of a commercial 65 nm CMOS technology for high energy physics applications

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Lili, E-mail: lili03.ding@gmail.com [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); State Key Laboratory of Pulsed Radiation Simulation and Effect, Northwest Institute of Nuclear Technology, Xi' an (China); Gerardin, Simone [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); Bagatin, Marta [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); Bisello, Dario [Department of Physics and Astronomy, Padova University, Via Marzolo 8, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); Mattiazzo, Serena [Department of Physics and Astronomy, Padova University, Via Marzolo 8, 35131 Padova (Italy); Paccagnella, Alessandro [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy)

    2016-09-21

    This paper reports the radiation tolerance study of a commercial 65 nm technology, which is a strong candidate for the Large Hadron Collider applications. After exposure to 3 MeV protons till 1 Grad dose, the 65 nm CMOS transistors, especially the pMOSFETs, showed severe long-term degradation mainly in the saturation drain currents. There were some differences between the degradation levels in the nMOSFETs and the pMOSFETs, which were likely attributed to the positive charges trapped in the gate spacers. After exposure to heavy ions till multiple strikes, the pMOSFETs did not show any sudden loss of drain currents, the degradations in the characteristics were negligible.

  15. Note: Commercial SQUID magnetometer-compatible NMR probe and its application for studying a quantum magnet

    Science.gov (United States)

    Vennemann, T.; Jeong, M.; Yoon, D.; Magrez, A.; Berger, H.; Yang, L.; Živković, I.; Babkevich, P.; Rønnow, H. M.

    2018-04-01

    We present a compact nuclear magnetic resonance (NMR) probe which is compatible with a magnet of a commercial superconducting quantum interference device magnetometer and demonstrate its application to the study of a quantum magnet. We employ trimmer chip capacitors to construct an NMR tank circuit for low temperature measurements. Using a magnetic insulator MoOPO4 with S = 1/2 (Mo5+) as an example, we show that the T-dependence of the circuit is weak enough to allow the ligand-ion NMR study of magnetic systems. Our 31P NMR results are compatible with previous bulk susceptibility and neutron scattering experiments and furthermore reveal unconventional spin dynamics.

  16. Economic costs and benefits of commercial food irradiation

    International Nuclear Information System (INIS)

    Wills, P. A; Freeman, D. J.

    1985-01-01

    Decisions about commercialization of potential food irradiation applications usually involve pre-feasibility and feasibility studies to assess the expected return on investment. In this paper treatment costa/charges in theory and practice, investment philosophy, and the role of the multi-purpose plant in food irradiation are discussed. Other countries benefit commercially from the irradiation of a limited range of foods, including spices and frozen shrimps, exported from Southeast Asia. Some aspects of the feasibility of commercially irradiating these products, as well as mangoes and grains, in ASEAN countries and Australia are examined

  17. Evaluation of PCR and DNA hybridization protocols for detection of viable enterotoxigenic Clostridium perfringens in irradiated beef

    International Nuclear Information System (INIS)

    Baez, L.A.; Juneja, V.K.; Thayer, D.W.; Sackitey, S.

    1997-01-01

    The sensitivity of DNA hybridization and polymerase chain reaction (PCR), was evaluated in irradiated cooked and raw beef samples. A membrane-based colony hybridization assay and a PCR protocol, both with specificity for the enterotoxin A gene of Clostridium perfringens, were compared with viable plate counts. The results of the colony hybridization procedure were in agreement with viable plate counts for detection and enumeration of enterotoxigenic C. perfringens. The PCR procedure combined a 4 h enrichment followed by a nucleic acid extraction step and assessed the amplification of 183 and 750 base pair enterotoxin gene targets. Detection of C. perfringens by PCR did not show a reliable correlation with viable plate counts or the colony hybridization assay. C. perfringens killed by irradiation were not detected by the plate count or colony hybridization methods; however, killed cells were detected with the PCR technique. By relying on the growth of viable cells for detection and/or enumeration, the colony hybridization and plate count methods provided a direct correlation with the presence of viable bacteria

  18. Molecular bacterial diversity and bioburden of commercial airliner cabin air

    Energy Technology Data Exchange (ETDEWEB)

    La Duc, M.T.; Stuecker, T.; Venkateswaran, K. [California Inst. of Technology, Pasadena, CA (United States). Jet Propulsion Laboratory, Biotechnology and Planetary Protection Group

    2007-11-15

    Microorganisms that exist in aircraft air systems are considered to be the primary source of microbial contamination that can lead to illness shortly after flying. More than 600 million passengers board commercial airline flights annually in the United States alone. In this study, culture-independent, biomarker-targeted bacterial enumeration and identification strategies were used to estimate total bacterial burden and diversity within the cabin air of commercial airliners. Air-impingement was used to collect samples of microorganisms from 4 flights on 2 commercial carriers. The total viable microbial population ranged from below detection limits to 4.1 x 10{sup 6} cells/m{sup 3} of air. Microbes were found to gradually accumulate from the time of passenger boarding through mid-flight. A sharp decline in bacterial abundance was then observed. Representatives of the {alpha}, {beta} and {gamma} Proteobacteria, as well as Gram-positive bacteria, were isolated in varying abundance. Airline A had large abundances of Neisseria meningitidis rRNA gene sequences and Streptococcus oralis/mitis sequences. Airline B was dominated by pseudomonas synxantha sequences as well as N. meningitidis and S. oralis/mitis. The cabin air samples housed low bacterial diversity and were typically dominated by a particular subset of bacteria, notably opportunistic pathogenic inhabitants of the human respiratory tract and oral cavity. The microbes were found largely around the ventilation ducts and gasper conduits that supply cabin air. 45 refs., 4 tabs., 3 figs.

  19. Survey VS audit by using method 2 to dedicate commercial grade services

    International Nuclear Information System (INIS)

    Martinez ayucar, F. J.

    2014-01-01

    Since the start of the commercial grade dedications, both 10CFR21 and EPRI documents, plus the dedication of commercial grade components, and the stage of commercial grade dedication of the services contemplated. And recently the NRC through various communications and answers trafficking among other issues the commercial grade dedication service. The NRC has detected repeatedly incorrect application of the survey as a method of commercial grade dedication and instead has done an audit of the program elements of commercial quality. (Author)

  20. Acupuntura un tratamiento viable para las adicciones en Colombia

    Directory of Open Access Journals (Sweden)

    Hernán López Seuscún

    2013-07-01

    Los tratamientos con auriculoterapia, como el protocolo NADA (National Acupuncture Detoxification Association, son los métodos más usados para las adicciones en el mundo, y aunque no se ha logrado evidenciar su efectividad, por su costo, facilidad y el poco riesgo de efectos adversos se hace viable en un país con pocos recursos económicos como Colombia.

  1. On the use of the serial dilution culture method to enumerate viable phytoplankton in natural communities of plankton subjected to ballast water treatment.

    Science.gov (United States)

    Cullen, John J; MacIntyre, Hugh L

    2016-01-01

    Discharge standards for ballast water treatment (BWT) systems are based on concentrations of living cells, for example, as determined with vital stains. Ultraviolet radiation (UV) stops the reproduction of microorganisms without killing them outright; they are living, but not viable, and ecologically as good as dead. Consequently, UV-treated discharge can be compliant with the intent of regulation while failing a live/dead test. An alternative evaluation of BWT can be proposed based on the assessment of viable, rather than living, cells in discharge water. In principle, the serial dilution culture-most probable number (SDC-MPN) method provides the appropriate measure for phytoplankton. But, the method has been criticized, particularly because it is thought that many phytoplankton species cannot be cultured. A review of the literature shows that although SDC-MPN has been used for more than 50 years-generally to identify and count phytoplankton species that cannot be preserved-its application to enumerate total viable phytoplankton seems to be new, putting past criticisms of the method in a different light. Importantly, viable cells need to grow only enough to be detected, not to be brought into sustained culture, and competition between species in a dilution tube is irrelevant as long as the winner is detectable. Thorough consideration of sources of error leads to recommendations for minimizing and quantifying uncertainties by optimizing growth conditions and conducting systematic comparisons. We conclude that with careful evaluation, SDC-MPN is potentially an effective method for assessing the viability of phytoplankton after BWT.

  2. Comparison of mechanical compressive properties of commercial and autologous fibrin glues for tissue engineering applications.

    Science.gov (United States)

    Cravens, Matthew G; Behn, Anthony W; Dragoo, Jason L

    2017-11-01

    Fibrin glues are widely used in orthopedic surgery as adhesives and hemostatic agents. We evaluated the compressive properties of selected fibrin glues in order to identify which are appropriate for tissue regeneration applications subject to compression. Uniaxial unconfined compression tests were performed on fibrin gels prepared from commercial and autologous products: (1) Evicel (Ethicon), (2) Tisseel (Baxter), (3) Angel (Arthrex), and (4) ProPlaz (Biorich). Cyclic loads were applied from 0 to 30% strain for 100cycles at 0.5Hz. Following cyclic testing, specimens were subjected to ramp displacement of 1% strain per second to 80% strain. Throughout cyclic loading, Evicel and Tisseel deformed (shortened) less than Angel at all but one time point, and deformed less than ProPlaz at cycles 10 and 20. The dynamic moduli, peak stress, and strain energy were significantly greater in Tisseel than all other groups. Evicel displayed significantly greater dynamic moduli, peak stress, and strain energy than Angel and ProPlaz. Following cyclic testing, Tisseel and Evicel were significantly less deformed than Angel. No specimens exhibited gross failure during ramp loading to 80% strain. Ramp loading trends mirrored those of cyclic loading. The tested commercial glues were significantly more resistant to compression than the autologous products. The compressive properties of Tisseel were approximately twice those of Evicel. All preparations displayed moduli multiple orders of magnitude less than that of native articular cartilage. We conclude that in knee surgeries requiring fibrin glue to undergo compression of daily activity, commercial products are preferable to autologous preparations from platelet-poor plasma, though both will deform significantly. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Gel-sphere-pac reactor fuel fabrication and its application to a variety of fuels

    International Nuclear Information System (INIS)

    Olsen, A.R.; Judkins, R.R.

    1979-12-01

    The gel-sphere-pac fuel fabrication option was evaluated for its possible application to commercial scale fuel fabrication for 19 fuel element designs that use oxide fuel in metal clad rods. The dry gel spheres are prepared at the reprocessing plant and are then calcined, sintered, inspected, and loaded into fuel rods and packed by low-energy vibration. A fuel smear density of 83 to 88% theoretical can be obtained. All fuel fabrication process steps were defined and evaluated from fuel receiving to finished fuel element shipping. The evaluation also covers the feasibility of the process, the current status of technology, estimates of the required time and cost to develop the technology to commercial status, and the safety and licensability of commercial scale plants. The primary evaluation was for a Light-Water Reactor fuel element containing (U,Pu)O 2 fuel. The other 18 fuel element types - 3 for Light-Water Reactors, 1 for a Heavy-Water Reactor, 1 for a Gas-Cooled Fast Reactor, 7 for Liquid-Metal-Cooled Fast Breeder Reactors, and 3 pairs for Light-Water Prebreeder and Breeder Reactors - were compared with the Light-Water Reactor. The gel-sphere-pac option was found applicable to 17 of the 19 element types; the characteristics of a commercial scale plant were defined for these for making cost estimates for such plants. The evaluation clearly shows the gel-sphere-pac process to be a viable fuel fabrication option. Estimates indicate a significant potential fabrication cost advantage for the gel-sphere-pac process if a remotely operated and remotely maintained fuel fabrication plant is required

  4. Decommissioning commercial nuclear facilities: a review and analysis of current regulations

    International Nuclear Information System (INIS)

    Schilling, A.H.; Lippek, H.E.; Tegeler, P.D.; Easterling, J.D.

    1979-08-01

    This report describes and analyzes the regulatory requirements and guidelines applicable to the decommissioning of commercial light water reactors, other commercial nuclear fuel cycle facilities, and byproduct utilization facilities, as contained principally in the United States Code, the United States Code of Federal Regulations, and the United States Nuclear Regulatory Commission's Regulatory Guides. State requirements are discussed where appropriate. The report provides general background informaion to license applicants and to other interested parties. Included is an outline of procedural steps required of an applicant to comply with decommissioning regulatory requiremets

  5. The search for viable local government system in Nigeria: an ...

    African Journals Online (AJOL)

    The history of the Nigerian local government system has been one long episode of trails and errors aimed at achieving viable local government institution without much success. Local government in the country began its long series of reforms from the colonial period when the colonial government attempted to ...

  6. The application of irradiation techniques for food preservation and process improvement -Studies on application of radiation and radioisotopes-

    International Nuclear Information System (INIS)

    Byeon, Myeong Uh; Cho, Han Ok; Yang, Jae Seung; Cho, Seong Ki; Kang, Il Joon

    1994-07-01

    With the increased consumption of processed food, quality control techniques are inevitably required in the food industry for its mass production and distribution. Recently, there has been a growing interest in the use of irradiation for solving the infrastructural problems in the food industry by developing viable alternatives to conventional technology and by improving the quality of processed foods. Even though food irradiation technology has been commercialized in 25 countries, and 18 items of irradiated foods have been approved for human consumption domestically, infrastructural studies are needed for the practical application of this technology. In order to enlarge the utilization of irradiation technology in solving the infrastructural problems of the food industry, this project was designed to investigate the efficacy of gamma irradiation for improving the process and physical properties of dried foods (corn and soybean), for preserving the reserved foods for emergency (red pepper) and for producing natural products (red polyketied pigment) using microbial immobilization with radiation-induced polymer

  7. Commercial objectives, technology transfer, and systems analysis for fusion power development

    Science.gov (United States)

    Dean, Stephen O.

    1988-09-01

    Fusion is an inexhaustible source of energy that has the potential for economic commercial applications with excellent safety and environmental characteristics. The primary focus for the fusion energy development program is the generation of central station electricity. Fusion has the potential, however, for many other applications. The fact that a large fraction of the energy released in a DT fusion reaction is carried by high energy neutrons suggests potentially unique applications. In addition, fusion R and D will lead to new products and new markets. Each fusion application must meet certain standards of economic and safety and environmental attractiveness. For this reason, economics on the one hand, and safety and environment and licensing on the other, are the two primary criteria for setting long range commercial fusion objectives. A major function of systems analysis is to evaluate the potential of fusion against these objectives and to help guide the fusion R and D program toward practical applications. The transfer of fusion technology and skills from the national labs and universities to industry is the key to achieving the long range objective of commercial fusion applications.

  8. NASA's commercial research plans and opportunities

    Science.gov (United States)

    Arnold, Ray J.

    One of the primary goals of the National Aeronautics and Space Administration's (NASA) commercial space development plan is to encourage the development of space-based products and markets, along with the infrastructure and transportation that will support those products and markets. A three phased program has been instituted to carry out this program. The first phase utilizes government grants through the Centers for the Commercial Development of Space (CCDS) for space-related, industry driven research; the development of a technology data base; and the development of commercial space transportation and infrastructure. The second phase includes the development of these technologies by industry for new commercial markets, and features unique industry/government collaborations such as Joint Endeavor Agreements. The final phase will feature technical applications actually brought to the marketplace. The government's role will be to support industry required infrastructure to encourage start-up markets and industries through follow-on development agreements such as the Space Systems Development Agreement. The Office of Commercial Programs has an aggressive flight program underway on the Space Shuttle, suborbital rockets, orbital expendable launch vehicles, and the Commercial Middeck Accommodation Module with SPACEHAB Inc. The Office of Commercial Program's has been allocated 35 percent of the U.S. share of the Space Station Freedom resources for 1997 utilization. A utilization plan has been developed with the Centers for the Commercial Development of Space and has identified eleven materials processing and biotechnology payloads occupying 5 double racks in the pressurized module as well as two payloads external to the module in materials exposure and environment monitoring. The Office of Commercial Programs will rely on the Space Station Freedom to provide the long duration laboratory component for space-based commercial research.

  9. Surveillance of bulk raw and commercially pasteurized cows' milk from approved Irish liquid-milk pasteurization plants to determine the incidence of Mycobacterium paratuberculosis.

    Science.gov (United States)

    O'Reilly, Ciara E; O'Connor, Lisa; Anderson, Wayne; Harvey, Peter; Grant, Irene R; Donaghy, John; Rowe, Michael; O'Mahony, Pat

    2004-09-01

    Over the 13-month period from October 2000 to November 2001 (inclusive), the Food Safety Authority of Ireland (FSAI) carried out surveillance of Irish bulk raw (n = 389) and commercially pasteurized (n = 357) liquid-milk supplies to determine the incidence of Mycobacterium paratuberculosis. The pasteurization time-temperature conditions were recorded for all pasteurized samples. Overall, 56% of whole-milk pasteurized samples had been heat treated at or above a time-temperature combination of 75 degrees C for 25 s. All analyses were undertaken at the Department of Food Science (Food Microbiology) laboratory at Queen's University Belfast. Each milk sample was subjected to two tests for M. paratuberculosis: immunomagnetic separation-PCR (IMS-PCR; to detect the presence of M. paratuberculosis cells, live or dead) and chemical decontamination and culture (to confirm the presence of viable M. paratuberculosis). Overall, M. paratuberculosis DNA was detected by IMS-PCR in 50 (12.9%; 95% confidence interval, 9.9 to 16.5%) raw-milk samples and 35 (9.8%; 95% confidence interval, 7.1 to 13.3%) pasteurized-milk samples. Confirmed M. paratuberculosis was cultured from one raw-milk sample and no pasteurized-milk samples. It is concluded that M. paratuberculosis DNA is occasionally present at low levels in both raw and commercially pasteurized cows' milk. However, since no viable M. paratuberculosis was isolated from commercially pasteurized cows' milk on retail sale in the Republic of Ireland, current pasteurization procedures are considered to be effective.

  10. Tropical Fruit Irradiation-From Research to Commercial Application

    International Nuclear Information System (INIS)

    Moy, James H.

    2005-09-01

    Food irradiation is an emerging technology for the 21st century. Extensive research and development worldwide in the past 40 years have proved the versatility and efficacy. With low, medium to high dose, and using either a gamma, electrons, or x-ray source, radiation can: 1) disinfest plant products and spices; 2) extend shelf life of tubers, bulbs, and selected tropical fruits; 3) decontaminate meats and seafood; 4) sterilize spices and special meals; and 5) improve product utilization. Criteria for testing its efficacy include effectiveness, efficiency, and the ability to retain product quality. The use of irradiation as a quarantine treatment of tropical fruits is potentially attractive to countries growing these fruits. A two-prong research plan should aim at proving radiation's effectiveness in preventing emergence of all insect pests that might be on a fruit, and determining that all quality attributes of a host fruit are retained after irradiation, subsequent storage and shipment. ommercial application involves conducting an economical feasibility study; market research and testing; selection of radiation source and irradiator type; training of personnel for plant operations, radiation safety and dosimetry monitoring; designing of packages and choosing the most cost-effective means of transporting treated fruits to market destinations. When all of hese are achieved, it should lead to a continuous and profitable operation. Researchers at the University of Hawaii using a gamma irradiator from the mid-1960s to early 2000s had amassed a volume of data to prove the efficacy of radiation disinfestations. And installation of a commercial x-ray irradiator in 2000 on the Island of Hawaii has enabled fruit farmers and packers to use this technology for exporting tropical fruits to distant markets

  11. Thermal Environment evaluation in Commercial kitchens

    DEFF Research Database (Denmark)

    Simone, Angela; Olesen, Bjarne W.

    2012-01-01

    as commercial kitchens? There is therefore a need to study the indoor environment in commercial kitchens and to establish standardized methods and procedures for setting criteria that have to be met for the design and operation of kitchens. The present paper introduces a data collection protocol based......The indoor climate in commercial kitchens is often unsatisfactory and the working conditions can have a significant effect on employees’ comfort and productivity. The type (fast food, casual, etc.) and climatic zone can influence the thermal conditions in the kitchens. Moreover, size...... and arrangement of the kitchen zones, appliances, etc., complicate further an evaluation of the indoor thermal environment in kitchens. In general, comfort criteria are expressed in international standards such as ASHRAE 55 or ISO EN7730. But are these standardised methods applicable for such environments...

  12. Assessments of Total and Viable Escherichia coli O157:H7 on Field and Laboratory Grown Lettuce

    Science.gov (United States)

    Moyne, Anne-Laure; Harris, Linda J.; Marco, Maria L.

    2013-01-01

    Leafy green produce has been associated with numerous outbreaks of foodborne illness caused by strains of Escherichia coli O157:H7. While the amounts of culturable E. coli O157:H7 rapidly decline after introduction onto lettuce in the field, it remains to be determined whether the reduction in cell numbers is due to losses in cell viability, cell injury and a subsequent inability to be detected by standard laboratory culturing methods, or a lack of adherence and hence rapid removal of the organism from the plants during application. To assess which of these options is most relevant for E. coli O157:H7 on leafy green produce, we developed and applied a propidium monoazide (PMA) real-time PCR assay to quantify viable (with PMA) and total (without PMA) E. coli O157:H7 cells on growth chamber and field-grown lettuce. E. coli O157:H7, suspended in 0.1% peptone, was inoculated onto 4-week-old lettuce plants at a level of approximately 106 CFU/plant. In the growth chamber at low relative humidity (30%), culturable amounts of the nontoxigenic E. coli O157:H7 strain ATCC 700728 and the virulent strain EC4045 declined 100 to 1000-fold in 24 h. Fewer E. coli O157:H7 cells survived when applied onto plants in droplets with a pipette compared with a fine spray inoculation. Total cells for both strains were equivalent to inoculum levels for 7 days after application, and viable cell quantities determined by PMA real-time PCR were approximately 104 greater than found by colony enumeration. Within 2 h after application onto plants in the field, the number of culturable E. coli ATCC 700728 was reduced by up to 1000-fold, whereas PCR-based assessments showed that total cell amounts were equivalent to inoculum levels. These findings show that shortly after inoculation onto plants, the majority of E. coli O157:H7 cells either die or are no longer culturable. PMID:23936235

  13. Continuous country-wide rainfall observation using a large network of commercial microwave links: Challenges, solutions and applications

    Science.gov (United States)

    Chwala, Christian; Boose, Yvonne; Smiatek, Gerhard; Kunstmann, Harald

    2017-04-01

    Commercial microwave link (CML) networks have proven to be a valuable source for rainfall information over the last years. However, up to now, analysis of CML data was always limited to certain snapshots of data for historic periods due to limited data access. With the real-time availability of CML data in Germany (Chwala et al. 2016) this situation has improved significantly. We are continuously acquiring and processing data from 3000 CMLs in Germany in near real-time with one minute temporal resolution. Currently the data acquisition system is extended to 10000 CMLs so that the whole of Germany is covered and a continuous country-wide rainfall product can be provided. In this contribution we will elaborate on the challenges and solutions regarding data acquisition, data management and robust processing. We will present the details of our data acquisition system that we run operationally at the network of the CML operator Ericsson Germany to solve the problem of limited data availability. Furthermore we will explain the implementation of our data base, its web-frontend for easy data access and present our data processing algorithms. Finally we will showcase an application of our data in hydrological modeling and its potential usage to improve radar QPE. Bibliography: Chwala, C., Keis, F., and Kunstmann, H.: Real-time data acquisition of commercial microwave link networks for hydrometeorological applications, Atmos. Meas. Tech., 9, 991-999, doi:10.5194/amt-9-991-2016, 2016

  14. Solid-state graft copolymer electrolytes for lithium battery applications.

    Science.gov (United States)

    Hu, Qichao; Caputo, Antonio; Sadoway, Donald R

    2013-08-12

    Battery safety has been a very important research area over the past decade. Commercially available lithium ion batteries employ low flash point (battery costs and can malfunction which can lead to battery malfunction and explosions, thus endangering human life. Increases in petroleum prices lead to a huge demand for safe, electric hybrid vehicles that are more economically viable to operate as oil prices continue to rise. Existing organic based electrolytes used in lithium ion batteries are not applicable to high temperature automotive applications. A safer alternative to organic electrolytes is solid polymer electrolytes. This work will highlight the synthesis for a graft copolymer electrolyte (GCE) poly(oxyethylene) methacrylate (POEM) to a block with a lower glass transition temperature (Tg) poly(oxyethylene) acrylate (POEA). The conduction mechanism has been discussed and it has been demonstrated the relationship between polymer segmental motion and ionic conductivity indeed has a Vogel-Tammann-Fulcher (VTF) dependence. Batteries containing commercially available LP30 organic (LiPF6 in ethylene carbonate (EC):dimethyl carbonate (DMC) at a 1:1 ratio) and GCE were cycled at ambient temperature. It was found that at ambient temperature, the batteries containing GCE showed a greater overpotential when compared to LP30 electrolyte. However at temperatures greater than 60 °C, the GCE cell exhibited much lower overpotential due to fast polymer electrolyte conductivity and nearly the full theoretical specific capacity of 170 mAh/g was accessed.

  15. New materials for next-generation commercial transports

    National Research Council Canada - National Science Library

    Committee on New Materials for Advanced Civil Aircraft, Commission on Engineering and Technical Systems, National Research Council

    ... civil aircraft throughout their service life. The committee investigated the new materials and structural concepts that are likely to be incorporated into next generation commercial aircraft and the factors influencing application decisions...

  16. Deep Ultra-Violet (DUV) Light Emitting Diodes

    National Research Council Canada - National Science Library

    Singh, Deepika

    2003-01-01

    Problems to Overcome: The main problem to overcome is to develop a commercially and economically viable method to synthesize and process high crystalline quality diamond films for applications such as DUV LEDs and solar-blind detectors...

  17. History and current status of commercial pulsed laser deposition equipment

    International Nuclear Information System (INIS)

    Greer, James A

    2014-01-01

    This paper will review the history of the scale-up of the pulsed laser deposition (PLD) process from small areas ∼1 cm 2 up to 10 m 2 starting in about 1987. It also documents the history of commercialization of PLD as various companies become involved in selling fully integrated laser deposition tools starting in 1989. The paper will highlight the current state of the art of commercial PLD equipment for R and D that is available on the market today from mainstream vendors as well as production-oriented applications directed at piezo-electric materials for microelectromechanical systems and high-temperature superconductors for coated-conductor applications. The paper clearly demonstrates that considerable improvements have been made to scaling this unique physical vapour deposition process to useful substrate sizes, and that commercial deposition equipment is readily available from a variety of vendors to address a wide variety of technologically important thin-film applications. (paper)

  18. Glioma Surgical Aspirate: A Viable Source of Tumor Tissue for Experimental Research

    International Nuclear Information System (INIS)

    Day, Bryan W.; Stringer, Brett W.; Wilson, John; Jeffree, Rosalind L.; Jamieson, Paul R.

    2013-01-01

    Brain cancer research has been hampered by a paucity of viable clinical tissue of sufficient quality and quantity for experimental research. This has driven researchers to rely heavily on long term cultured cells which no longer represent the cancers from which they were derived. Resection of brain tumors, particularly at the interface between normal and tumorigenic tissue, can be carried out using an ultrasonic surgical aspirator (CUSA) that deposits liquid (blood and irrigation fluid) and resected tissue into a sterile bottle for disposal. To determine the utility of CUSA-derived glioma tissue for experimental research, we collected 48 CUSA specimen bottles from glioma patients and analyzed both the solid tissue fragments and dissociated tumor cells suspended in the liquid waste fraction. We investigated if these fractions would be useful for analyzing tumor heterogeneity, using IHC and multi-parameter flow cytometry; we also assessed culture generation and orthotopic xenograft potential. Both cell sources proved to be an abundant, highly viable source of live tumor cells for cytometric analysis, animal studies and in-vitro studies. Our findings demonstrate that CUSA tissue represents an abundant viable source to conduct experimental research and to carry out diagnostic analyses by flow cytometry or other molecular diagnostic procedures

  19. Commercial products and services of research reactors. Proceedings of a technical meeting

    International Nuclear Information System (INIS)

    2013-07-01

    enhance the utilization of research reactors and their sustainability through financially viable services and international cooperation. In this report, reference is also made to a similar IAEA technical meeting on “Commercial Applications of Nuclear Analytical Techniques”, held in Vienna, Austria, from 23 to 26 November 2004, and a few recently updated papers from that meeting have been included here. This publication summarizes the individual reports presented during the above meetings, and details the overall findings and conclusions jointly identified and agreed upon by the meeting participants. This publication summarizes the individual reports presented during the above meetings and details the overall findings and conclusions jointly identified and agreed upon by the meeting participants. The individual papers are available via the drop-down menus on the left menu

  20. El modelo de sistema viable: un instrumento para la organización efectiva

    Directory of Open Access Journals (Sweden)

    Norlando Sánchez Rueda

    2015-05-01

    Full Text Available RESUMEN En este ensayo se presenta una interpretación teórica del denominado Modelo de Sistema Viable (MSV, de Stafford Beer y su Potencial Aplicación en Tareas de Diagnóstico  y diseño empresarial, al igual que para Mejorar las capacidades Organizacionales de Auto- Regulación  y Auto- Organización. Se explica como el Modelo del Sistema Viable permite conocer e interpretar  los mecanismos de estabilidad y adaptabilidad de las organizaciones, pilares para el crecimiento de una verdadera organización Efectiva.

  1. Ionizing radiation quarantine treatments

    OpenAIRE

    Hallman, Guy J.

    1998-01-01

    Irradiation is a viable quarantine disinfestation treatment which has been studied for 40 years although it has received very little commercial use. Two principal obstacles to commercial application, 1) the fact that insects are not killed immediately, and 2) consumer opposition to irradiation, have been allayed to some extent, but the remaining impediment to large-scale commercial use is development of approved protocols by government regulatory agencies in importing countries. The United St...

  2. Formulation of a Commercial Biosurfactant for Application as a Dispersant of Petroleum and By-products Spilled in Oceans

    Directory of Open Access Journals (Sweden)

    Bruno Galdino Freitas

    2016-10-01

    Full Text Available Oil spills in oceans cause irreparable damage to marine life and harm the coastal populations of affected areas. It is therefore fundamental to develop treatment strategies for such spills. Currently, chemical dispersants have been used during oil spills, although these agents have been increasingly restricted due to their toxic potential. Thus, the aim of the present study was to formulate a biodegradable commercial biosurfactant for application as a dispersant. Biosurfactants are scientifically known biomolecules produced by microorganisms capable of allowing water-oil interaction. Thus, a biosurfactant was produced by the yeast Candida bombicola URM 3718 cultivated in industrial waste and formulated with the addition of a potassium sorbate preservative for fractionated sterilisation (tyndallisation and the combination of fluent vaporisation with the preservative. After formulation, samples were stored for 120 days, followed by surface tension, emulsification and oil dispersant tests in sea water. The results were promising for the biosurfactant formulated with the preservative, which demonstrated stability and an absence of toxicity in experiments with a marine indicator. The commercial biosurfactant was tested at different pH values, temperatures and in the presence of salt, demonstrating potential industrial application at a cost compatible with the environmental field. The formulation process developed in this research was patented in the Brazilian National Intellectual Property Institute (patent number BR1020140179631.

  3. Dendritic cells for active immunotherapy: optimizing design and manufacture in order to develop commercially and clinically viable products.

    Science.gov (United States)

    Nicolette, C A; Healey, D; Tcherepanova, I; Whelton, P; Monesmith, T; Coombs, L; Finke, L H; Whiteside, T; Miesowicz, F

    2007-09-27

    Dendritic cell (DC) active immunotherapy is potentially efficacious in a broad array of malignant disease settings. However, challenges remain in optimizing DC-based therapy for maximum clinical efficacy within manufacturing processes that permit quality control and scale-up of consistent products. In this review we discuss the critical issues that must be addressed in order to optimize DC-based product design and manufacture, and highlight the DC based platforms currently addressing these issues. Variables in DC-based product design include the type of antigenic payload used, DC maturation steps and activation processes, and functional assays. Issues to consider in development include: (a) minimizing the invasiveness of patient biological material collection; (b) minimizing handling and manipulations of tissue at the clinical site; (c) centralized product manufacturing and standardized processing and capacity for commercial-scale production; (d) rapid product release turnaround time; (e) the ability to manufacture sufficient product from limited starting material; and (f) standardized release criteria for DC phenotype and function. Improvements in the design and manufacture of DC products have resulted in a handful of promising leads currently in clinical development.

  4. Facility overview for commercial application of selected Rocky Flats facilities

    International Nuclear Information System (INIS)

    1996-11-01

    The purpose of this Facility Overview is to support the Rocky Flats Local Impacts Initiative's Request for Interest, to solicit interest from commercial corporations for utilizing buildings 865 and 883, and the equipment contained within each building, for a commercial venture. In the following sections, this document describes the Rocky Flats Site, the buildings available for lease, the equipment within these buildings, the site services available to a tenant, the human resources available to support operations in buildings 865 and 883, and the environmental condition of the buildings and property. In addition, a brief description is provided of the work performed to date to explore the potential products that might be manufactured in Buildings 865 and 883, and the markets for these products

  5. Digimarc MediaBridge: the birth of a consumer product from concept to commercial application

    Science.gov (United States)

    Perry, Burt; MacIntosh, Brian; Cushman, David

    2002-04-01

    This paper examines the issues encountered in the development and commercial deployment of a system based on digital watermarking technology. The paper provides an overview of the development of digital watermarking technology and the first applications to use the technology. It also looks at how we took the concept of digital watermarking as a communications channel within a digital environment and applied it to the physical print world to produce the Digimarc MediaBridge product. We describe the engineering tradeoffs that were made to balance competing requirements of watermark robustness, image quality, embedding process, detection speed and end user ease of use. Today, the Digimarc MediaBridge product links printed materials to auxiliary information about the content, via the Internet, to provide enhanced informational marketing, promotion, advertising and commerce opportunities.

  6. Comparison of culture-based, vital stain and PMA-qPCR methods for the quantitative detection of viable hookworm ova.

    Science.gov (United States)

    Gyawali, P; Sidhu, J P S; Ahmed, W; Jagals, P; Toze, S

    2017-06-01

    Accurate quantitative measurement of viable hookworm ova from environmental samples is the key to controlling hookworm re-infections in the endemic regions. In this study, the accuracy of three quantitative detection methods [culture-based, vital stain and propidium monoazide-quantitative polymerase chain reaction (PMA-qPCR)] was evaluated by enumerating 1,000 ± 50 Ancylostoma caninum ova in the laboratory. The culture-based method was able to quantify an average of 397 ± 59 viable hookworm ova. Similarly, vital stain and PMA-qPCR methods quantified 644 ± 87 and 587 ± 91 viable ova, respectively. The numbers of viable ova estimated by the culture-based method were significantly (P methods. Therefore, both PMA-qPCR and vital stain methods appear to be suitable for the quantitative detection of viable hookworm ova. However, PMA-qPCR would be preferable over the vital stain method in scenarios where ova speciation is needed.

  7. Energy conservation and the residential and commercial sector

    Science.gov (United States)

    1975-01-01

    A detailed analysis of energy conservation actions relevant to the residential and commercial sector has led to the conclusion that the potential for savings is great. The task will not be easy, however, since many of the actions require significant life style changes that are difficult to accomplish. Furthermore, many of the conservation actions cited as instant solutions to the energy crisis are those with only mid to long term potential, such as solar energy or heat pumps. Three significant conservation approaches are viable: adjusting price structure, mandating actions, and educating consumers. The first two appear to be the most feasible. But they are not without a price. Higher utility bills adversely affect the poor and the elderly on fixed incomes. Likewise, strict mandatory measures can be quite distasteful. But the effect of alternatives, such as voluntary savings accomplished through education processes, is minimal in a nation without a true conservation ethic.

  8. Weldability, machinability and surfacing of commercial duplex stainless steel AISI2205 for marine applications – A recent review

    Directory of Open Access Journals (Sweden)

    A. Vinoth Jebaraj

    2017-05-01

    Full Text Available In the present review, attempts have been made to analyze the metallurgical, mechanical, and corrosion properties of commercial marine alloy duplex stainless steel AISI 2205 with special reference to its weldability, machinability, and surfacing. In the first part, effects of various fusion and solid-state welding processes on joining DSS 2205 with similar and dissimilar metals are addressed. Microstructural changes during the weld cooling cycle such as austenite reformation, partitioning of alloying elements, HAZ transformations, and the intermetallic precipitations are analyzed and compared with the different welding techniques. In the second part, machinability of DSS 2205 is compared with the commercial ASS grades in order to justify the quality of machining. In the third part, the importance of surface quality in a marine exposure is emphasized and the enhancement of surface properties through peening techniques is highlighted. The research gaps and inferences highlighted in this review will be more useful for the fabrications involved in the marine applications.

  9. Development of wall thinning screening system and its application to a commercial nuclear power plant

    International Nuclear Information System (INIS)

    Ryu, Kyung Ha; Hwang, Il Soon; Kim, Ji Hyun

    2013-01-01

    Highlights: • Wall loss screening system (WalSS) has been developed based on ES-DCPD method. • Screening criteria was established based on the thinning of the actual shape that occur in the power plant. • With the criteria, the WalSS gives priority of the need for inspection. • This technique was successfully applied to commercial nuclear power plant. - Abstract: A new non-destructive evaluation (NDE) method has been developed for metal pipes for the detection wall thinning. The method has been showed to be suitable for applications to electric power generation plants where flow accelerated corrosion (FAC) of carbon steel piping is a significant cause of increased maintenance and plant personnel casualty. The wall thinning screening system (WalSS) was developed in two major phases. In the first phase, the equipotential switching direct current potential drop (ES-DCPD) method was developed for piping wall (Ryu et al., 2008a, 2010). In the second phase, in this paper, a quantitative detection criteria was developed. The relative ES-DCPD change of 3.8% has been defined as the screening criteria for wall thinning schematization. This criteria means that the component with measured ES-DCPD change greater than 3.8% is called for a more comprehensive examination. In the criteria development, all variables were taken into consideration based on commercial plant piping inspection data such as initial thickness distributions, wall thinning shape and nominal thickness. The developed WalSS based on ES-DCPD was applied to a moisture separator reheater (MSR) drain line of a commercial nuclear power plant (NPP) during a scheduled overhaul. The measured ES-DCPD change was 2.16%, which is lower than the ES-DCPD criteria, identifying the pipe having adequate wall thickness. This is confirmed by site thickness inspection using ultrasonic technique (UT)

  10. Microstructure and Mechanical Property of ODS Ferritic Steels Using Commercial Alloy Powders for High Temperature Service Applications

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Sanghoon; Choi, Byoung-Kwon; Kang, Suk Hoon; Kim, Tae Kyu [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Oxide dispersion strengthening (ODS) is one of the promising ways to improve the mechanical property at high temperatures. This is mainly attributed to uniformly distributed nano-oxide particle with a high density, which is extremely stable at the high temperature and acts as effective obstacles when the dislocations are moving. In this study, as a preliminary examination to develop the advanced structural materials for high temperature service applications, ODS ferritic steels were fabricated using commercial alloy powders and their microstructural and mechanical properties were investigated. In this study, ODS ferritic steels were fabricated using commercial stainless steel 430L powder and their microstructures and mechanical properties were investigated. Morphology of micro-grains and oxide particles were significantly changed by the addition of minor alloying elements such as Ti, Zr, and Hf. The ODS ferritic steel with Zr and Hf additions showed ultra-fine grains with fine complex oxide particles. The oxide particles were uniformly located in grains and on the grain boundaries. This led to higher hardness than ODS ferritic steel with Ti addition.

  11. Characterization of commercial supercapacitors for low temperature applications

    OpenAIRE

    Iwama, Etsuro; Taberna, Pierre-Louis; Azais, Philippe; Brégeon, Laurent; Simon, Patrice

    2012-01-01

    International audience; Electrochemical characterizations at low temperature and floating tests have been performed on 600F commercial supercapacitor (SC) for acetonitrile (AN)-based and AN + methyl acetate (MA) mixed electrolytes. From −40 to +20 °C, AN electrolyte showed slightly higher capacitance than those of AN + MA mixed electrolytes (25 and 33 vol.% of MA). At −55 °C, however, AN electrolyte did not cycle at all, while MA mixed electrolyte normally cycled with a slight decrease in the...

  12. Economic feasibility of copepod production for commercial use

    DEFF Research Database (Denmark)

    Gedefaw Abate, Tenaw; Nielsen, Rasmus; Nielsen, Max

    2015-01-01

    of producing copepods for commercial application. This is the first empirical study to investigate the economic feasibility of copepod production for commercial use. To this end, a standard cost-benefit analysis based on a prototype production facility of Acartia tonsa (Dana) eggs at Roskilde University...... condition, reduces mal-pigmentation and allows breeding of ‘new’ marine finfish species. However, copepods are not yet commercially produced and therefore not widely used in the aquaculture industry. One of the bottlenecks for large-scale production has been lack of economic knowledge on the feasibility......, Denmark, is employed. The result reveals that commercial production of copepods is economically feasible considering the existing market prices on both copepods and competing live feed items such as rotifers. The study provides valuable information for businesses who consider investing in live feed...

  13. Design and dosimetry characteristics of a commercial applicator system for intra-operative electron beam therapy utilizing ELEKTA Precise accelerator.

    Science.gov (United States)

    Nevelsky, Alexander; Bernstein, Zvi; Bar-Deroma, Raquel; Kuten, Abraham; Orion, Itzhak

    2010-07-19

    The design concept and dosimetric characteristics of a new applicator system for intraoperative radiation therapy (IORT) are presented in this work. A new hard-docking commercial system includes polymethylmethacrylate (PMMA) applicators with different diameters and applicator end angles and a set of secondary lead collimators. A telescopic device allows changing of source-to-surface distance (SSD). All measurements were performed for 6, 9, 12 and 18 MeV electron energies. Output factors and percentage depth doses (PDD) were measured in a water phantom using a plane-parallel ion chamber. Isodose contours and radiation leakage were measured using a solid water phantom and radiographic films. The dependence of PDD on SSD was checked for the applicators with the smallest and the biggest diameters. SSD dependence of the output factors was measured. Hardcopies of PDD and isodose contours were prepared to help the team during the procedure on deciding applicator size and energy to be chosen. Applicator output factors are a function of energy, applicator size and applicator type. Dependence of SSD correction factors on applicator size and applicator type was found to be weak. The same SSD correction will be applied for all applicators in use for each energy. The radiation leakage through the applicators is clinically acceptable. The applicator system enables effective collimation of electron beams for IORT. The data presented are sufficient for applicator, energy and monitor unit selection for IORT treatment of a patient.

  14. TechTracS: NASA's commercial technology management system

    Science.gov (United States)

    Barquinero, Kevin; Cannon, Douglas

    1996-03-01

    The Commercial Technology Mission is a primary NASA mission, comparable in importance to those in aeronautics and space. This paper will discuss TechTracS, NASA Commercial Technology Management System that has been put into place in FY 1995 to implement this mission. This system is designed to identify and capture the NASA technologies which have commercial potential into an off-the-shelf database application, and then track the technologies' progress in realizing the commercial potential through collaborations with industry. The management system consists of four stages. The first is to develop an inventory database of the agency's entire technology portfolio and assess it for relevance to the commercial marketplace. Those technologies that are identified as having commercial potential will then be actively marketed to appropriate industries—this is the second stage. The third stage is when a NASA-industry partnership is entered into for the purposes of commercializing the technology. The final stage is to track the technology's success or failure in the marketplace. The collection of this information in TechTracS enables metrics evaluation and can accelerate the establishment on direct contacts between and NASA technologist and an industry technologist. This connection is the beginning of the technology commercialization process.

  15. On the Ambiguity of Commercial Open Source

    Directory of Open Access Journals (Sweden)

    Lucian Luca

    2006-01-01

    Full Text Available . Open source and commercial applications used to be two separate worlds. The former was the work of amateurs who had little interest in making a profit, while the latter was only profit oriented and was produced by big companies. Nowadays open source is a threat and an opportunity to serious businesses of all kinds, generating good profits while delivering low costs products to customers. The competition between commercial and open source software has impacted the industry and the society as a whole. But in the last years, the markets for commercial and open source software are converging rapidly and it is interesting to resume and discuss the implications of this new paradigm, taking into account arguments pro and against it.

  16. Computer Based Asset Management System For Commercial Banks

    Directory of Open Access Journals (Sweden)

    Amanze

    2015-08-01

    Full Text Available ABSTRACT The Computer-based Asset Management System is a web-based system. It allows commercial banks to keep track of their assets. The most advantages of this system are the effective management of asset by keeping records of the asset and retrieval of information. In this research I gather the information to define the requirements of the new application and look at factors how commercial banks managed their asset.

  17. Contracting of energy services: often a viable alternative

    International Nuclear Information System (INIS)

    Milic, M.; Bruendler, M.

    2001-01-01

    This article discusses the outsourcing of energy services as a viable alternative to the operation of own energy facilities. The advantages of contracting for enterprises wanting to focus on their core competencies and have their energy infrastructure financed, built, maintained and operated by a third party are discussed. Financial aspects are looked at and examples in connection with the calculation of actual energy costs are given. The article is concluded with tips on the evaluation of offers for contracting services and on the definition of ownership aspects and property boundaries

  18. Design of high entropy alloys based on the experience from commercial superalloys

    Science.gov (United States)

    Wang, Z.; Huang, Y.; Wang, J.; Liu, C. T.

    2015-01-01

    High entropy alloys (HEAs) have been drawing increasing attention recently and gratifying results have been obtained. However, the existing metallurgic rules of HEAs could not provide specific information of selecting candidate alloys for structural applications. Our brief survey reveals that many commercial superalloys have medium and even to high configurational entropies. The experience of commercial superalloys provides a clue for helping us in the development of HEAs for structural applications.

  19. Application of NAA and BA in chemical thinning of some commercial apple cultivars

    Directory of Open Access Journals (Sweden)

    Šebek Gordana

    2015-01-01

    Full Text Available This paper presents the fruit thinning response of some commercial apple cultivars to NAA and BA plant regulators. The experiment was designed to evaluate NAA applied separately at three concentrations - 13.2 ppm, 17.82 ppm and 26.73 ppm, and BA + NAA combinations (BA - 60 ppm, 100 ppm, 120 ppm or 140 ppm + NAA 4.29 ppm for thinning the assessed apple cultivars. All treatments with NAA and BA + NAA adequately thinned 'McIntosh' and 'Jonathan', whereas the application of NAA 17.82 ppm and 26.73 ppm and the combined treatment BA 140 ppm+ NAA 4.29 ppm were effective fruit thinners for 'Prima'. In terms of the average fruit weight, number of fruits categorized as large (> 75 mm or > 65 mm, and number of fruit per trunk cross-sectional area, the treatment BA 140 ppm + NAA 4.29 ppm was most effective on 'McIntosh' and 'Prima', whereas BA 100 ppm + NAA 4.29 ppm had the best effect on 'Jonathan'.

  20. Conceptual design of a hybrid KrF laser system for ICF commercial applications

    International Nuclear Information System (INIS)

    Harris, D.B.; Lowenthal, D.D.

    1986-01-01

    KrF lasers appear to be the most efficient lasers operating near the optimal wavelength for laser fusion. Most high-efficiency, low-cost KrF laser designs use large electron-beam driven amplifiers and use pure angular multiplexing for the required pulse compression. A recent study carried out by Los Alamos and Spectra Technology has defined a high-efficiency hybrid KrF laser system architecture that uses both angular multiplexing and Raman beam combination. The high overall system efficiency of this hybrid design, approximately 12%, is achieved primarily through the use of e-beam sustained discharge lasers (EBSDL), and by using the efficient forward rotational Raman process in hydrogen. The new system appears attractive as a commercial-applications driver because the calculated efficiency is higher than the usual large e-beam pumped (EBP) KrF laser/pure angular multiplexing approach. In this paper, the hybrid system architecture is described, and the tradeoffs with respect to the large EBP amplifier/angular multiplexed system are discussed

  1. Severe Plastic Deformation of Commercial Pure Titanium (CP-Ti) for Biomedical Applications: A Brief Review

    Science.gov (United States)

    Mahmoodian, Reza; Annuar, N. Syahira M.; Faraji, Ghader; Bahar, Nadia Dayana; Razak, Bushroa Abd; Sparham, Mahdi

    2017-11-01

    This paper reviews severe plastic deformation (SPD) techniques for producing ultrafine-grained (UFG) and nanostructured commercial pure titanium (CP-Ti) for biomedical applications as the best alternative to titanium alloys. SPD processes, effective parameters, and advantages of nanostructured CP-Ti over coarse-grained (CG) material and Ti alloys are briefly reviewed. It is reported that nanostructured CP-Ti processed via SPD exhibits higher mechanical strength comparable to Ti alloys but better biological response and superior biocompatibility. Also, different surface modification techniques offer different results on UFG and CG CP-Ti, leading to nanoscale surface topography in UFG samples. Overall, it is reported that nanostructured CP-Ti processed by SPD could be considered to be the best candidate for biomedical implants.

  2. European Perspectives on International Commercial Arbitration

    DEFF Research Database (Denmark)

    Hauberg Wilhelmsen, Louise

    2014-01-01

    of a uniform rule on the law applicable to the existence and validity of an arbitration agreement. This article examines these issues in order to find out whether they are only European or also inherent in the international regulation of international commercial arbitration. The article examines to which...

  3. The Commercial Energy Consumer: About Whom Are We Speaking?

    Energy Technology Data Exchange (ETDEWEB)

    Payne, Christopher

    2006-05-12

    Who are commercial sector customers, and how do they make decisions about energy consumption and energy efficiency investment? The energy policy field has not done a thorough job of describing energy consumption in the commercial sector. First, the discussion of the commercial sector itself is dominated by discussion of large businesses/buildings. Second, discussion of this portion of the commercial sectors consumption behavior is driven primarily by theory, with very little field data collected on the way commercial sector decision-makers describe their own options, choices, and reasons for taking action. These limitations artificially constrain energy policy options. This paper reviews the extant literature on commercial sector energy consumption behavior and identifies gaps in our knowledge. In particular, it argues that the primary energy policy model of commercial sector energy consumption is a top-down model that uses macro-level investment data to make conclusions about commercial behavior. Missing from the discussion is a model of consumption behavior that builds up to a theoretical framework informed by the micro-level data provided by commercial decision-makers themselves. Such a bottom-up model could enhance the effectiveness of commercial sector energy policy. In particular, translation of some behavioral models from the residential sector to the commercial sector may offer new opportunities for policies to change commercial energy consumption behavior. Utility bill consumption feedback is considered as one example of a policy option that may be applicable to both the residential and small commercial sector.

  4. Strategies for improving production performance of probiotic Pediococcus acidilactici viable cell by overcoming lactic acid inhibition.

    Science.gov (United States)

    Othman, Majdiah; Ariff, Arbakariya B; Wasoh, Helmi; Kapri, Mohd Rizal; Halim, Murni

    2017-11-27

    Lactic acid bacteria are industrially important microorganisms recognized for fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications. Fermentation conditions such as concentration of initial glucose in the culture, concentration of lactic acid accumulated in the culture, types of pH control strategy, types of aeration mode and different agitation speed had influenced the cultivation performance of batch fermentation of Pediococcus acidilactici. The maximum viable cell concentration obtained in constant fed-batch fermentation at a feeding rate of 0.015 L/h was 6.1 times higher with 1.6 times reduction in lactic acid accumulation compared to batch fermentation. Anion exchange resin, IRA 67 was found to have the highest selectivity towards lactic acid compared to other components studied. Fed-batch fermentation of P. acidilactici coupled with lactic acid removal system using IRA 67 resin showed 55.5 and 9.1 times of improvement in maximum viable cell concentration compared to fermentation without resin for batch and fed-batch mode respectively. The improvement of the P. acidilactici growth in the constant fed-batch fermentation indicated the use of minimal and simple process control equipment is an effective approach for reducing by-product inhibition. Further improvement in the cultivation performance of P. acidilactici in fed-bath fermentation with in situ addition of anion-exchange resin significantly helped to enhance the growth of P. acidilactici by reducing the inhibitory effect of lactic acid and thus increasing probiotic production.

  5. A multicenter study of viable PCR using propidium monoazide to detect Legionella in water samples.

    Science.gov (United States)

    Scaturro, Maria; Fontana, Stefano; Dell'eva, Italo; Helfer, Fabrizia; Marchio, Michele; Stefanetti, Maria Vittoria; Cavallaro, Mario; Miglietta, Marilena; Montagna, Maria Teresa; De Giglio, Osvalda; Cuna, Teresa; Chetti, Leonarda; Sabattini, Maria Antonietta Bucci; Carlotti, Michela; Viggiani, Mariagabriella; Stenico, Alberta; Romanin, Elisa; Bonanni, Emma; Ottaviano, Claudio; Franzin, Laura; Avanzini, Claudio; Demarie, Valerio; Corbella, Marta; Cambieri, Patrizia; Marone, Piero; Rota, Maria Cristina; Bella, Antonino; Ricci, Maria Luisa

    2016-07-01

    Legionella quantification in environmental samples is overestimated by qPCR. Combination with a viable dye, such as Propidium monoazide (PMA), could make qPCR (named then vPCR) very reliable. In this multicentre study 717 artificial water samples, spiked with fixed concentrations of Legionella and interfering bacterial flora, were analysed by qPCR, vPCR and culture and data were compared by statistical analysis. A heat-treatment at 55 °C for 10 minutes was also performed to obtain viable and not-viable bacteria. When data of vPCR were compared with those of culture and qPCR, statistical analysis showed significant differences (P 0.05). Overall this study provided a good experimental reproducibility of vPCR but also highlighted limits of PMA in the discriminating capability of dead and live bacteria, making vPCR not completely reliable. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Nuclear power technologies for application in developing countries

    International Nuclear Information System (INIS)

    Zrodnikov, A.V.

    2000-01-01

    The tremendous social and political changes which have occurred during the recent decade in the former USSR made it possible to launch the process of commercialization of defense-related technologies in Russia. The so-called dual-use technologies are meant to be initially developed by the state for defense needs, but having a high commercial potential as well. To date, the process of such technology transfer from the state sector to a private one has been limited primarily by insufficient progress of the national private sector. Essentially, the main economic problem still remains the attraction of private capital for the promotion of dual-use technologies to the point at where they acquire commercially viable. A large number of advanced technologies are waiting to be commercialized. The report presented considers the prospects of civil use of some technologies related to the nuclear power area: space nuclear power systems, nuclear powered submarines and rector-pumped lasers. (author)

  7. Commercial low-level radioactive waste management

    International Nuclear Information System (INIS)

    Coleman, J.A.

    1982-01-01

    The goals, objectives and activities of the Department of Energy's Low-Level Radioactive Waste Management program are reviewed. The goal of the overall Program is to support development of an acceptable, nationwide, near surface waste disposal system by 1986. The commercial LLW program has two major functions: (1) application of the technology improvements for waste handling, treatment and disposal, and (2) assistance to states as they carry out their responsibilities under the Low-Level Radioactive Waste Policy Act of 1980. The priorities for the commercial side of the Low-Level Waste Management Program have been established to meet one goal: to support development of an effective commercial management system by 1986. The first priority is being given to supporting state efforts in forming the institutional structures needed to manage the system. The second priority is the state and industry role in transferring and demonstrating treatment and disposal technologies

  8. Lithium-polymer batteries for EV applications. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, J.O. [Uppsala Univ. (Sweden). Dept. of Inorganic Chemistry

    2000-05-01

    The project initially held a strong 'battery materials' profile, but has moved in its final year into more 'battery engineering' aspects; the performances of a range of potential materials have been screened, and candidates have emerged. It is noteworthy that these same materials have also now become 'best-choice' materials in commercial Japanese Li-ion batteries for mobile-phone, lap-top and, more recently, even electric-vehicle (EV) applications. It is now clear that the Li-ion (polymer) battery offers a genuinely viable option in electric and electric-hybrid vehicle concepts. Specifically, our work has involved synthetic, structural, morphological and electrochemical studies of lithium insertion mechanisms in TMO-based cathodes (LiMn{sub 2}O{sub 4}, V{sub 6}O{sub 13}, LiCoO{sub 2}, LiFePO{sub 4}, etc) and graphitic carbon anodes. Performance has been optimised from cell capacity, power, shelf-life and safety viewpoints. Cost has also emerged as a critical variable. Novel methods have been developed within the project for elevated-temperature battery studies (up to 80 deg C); they have become widely applied internationally. The electrode materials which have been developed have subsequently been incorporated into laboratory-scale lithium-ion battery prototypes, whose performance has then been evaluated. The final phase of the project has focussed on a new cathode material (LiFePO{sub 4}) not in current commercial use and yet ideally suited to EV application by virtue of its cheapness, high capacity (ca 170 mAh/g), high voltage vs. Li (3.5V), and extremely flat discharge curve. This could well prove to be the 'best compromise' Li-ion battery cathode for EV applications in the future.

  9. Organizational, interface, and financial barriers to the commercial development of community energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Schladale, R.; Ritschard, R.

    1979-12-01

    The scope of this analysis was limited to systems producing electricity - the output of a community energy system typically falling in the range 10 kW to 150 MW. The purpose of this study was to identify the barriers that groups and individuals will face when attempting to commercialize community energy systems. Three particular classes of barriers were investigated: those within the organization attempting the commercialization, those that arise from attempts to link the community system with an electric utility, and those that impede the flow of investment capital into community energy systems. In summary, three general observations regarding community energy systems may be distilled from this study. First, although many barriers exist to the commercialization of the systems, few if any appear unresolvable. Perhaps most challenginng will be the problem of expanding the use of cogeneration and municipal sold waste while at the same time maintaining or improving ambient air quality. Second, the financial subsidies required to make community systems competitive are not extraordinary. Indeed, with the exception of photovoltaics they should not amount to more than about 10% of capital cost of the new systems, and mass production may eliminate the need for subsidies altogether at some point in the future. Third, the administrative and regulatory procedures required to make community energy systems viable appear to be taking shape in a positive and timely fashion.

  10. The criminal act of commercial surrogacy in Australia: a call for review.

    Science.gov (United States)

    Stuhmcke, Anita

    2011-03-01

    Australian surrogacy legislation punishes the pursuit of a commercial surrogacy arrangement as a criminal offence. Such legislation was first introduced in Victoria in 1986 and has since been applied in every Australian jurisdiction except for the Northern Territory. The current application of criminal law is based upon this 1980s policy which has never been subject to public debate. This article argues that the continued application of criminal penalties to commercial surrogacy requires review.

  11. Progress in gamma processing of commercial products

    International Nuclear Information System (INIS)

    Fraser, F.M.

    1988-01-01

    In this paper the global outlook for gamma radiation processing of commercial products is discussed. Canada's contribution to the development of the industry is presented. New developments in the applications of the process and its marketing are discussed. (U.K.)

  12. Commercial Bank Efficiency Evaluation in Consideration of the Undesirable Output and Its Link with Stakeholders Relationship: An Application of China’s Commercial Banks

    Directory of Open Access Journals (Sweden)

    Jianyue Ji

    2014-01-01

    Full Text Available Based on the modern contract theory, expectancy theory, and stakeholder theory, this paper analyzes how stakeholders relationship influences the efficiency of commercial banks and finds that the efficiency is a function of stakeholders relationship. A DEA model with Seiford's linear transformation function is developed to evaluate the efficiency in consideration of the undesirable output. The panel Tobit model is established to conduct empirical research with data of 14 Chinese commercial banks from 2004 to 2012. The study finds that except for business customer relation, stakeholder relationship is the key variable that influences comprehensive efficiency of commercial banks.

  13. Commercially developed mixed-signal CMOS process features for application in advanced ROICs in 0.18μm technology node

    Science.gov (United States)

    Kar-Roy, Arjun; Hurwitz, Paul; Mann, Richard; Qamar, Yasir; Chaudhry, Samir; Zwingman, Robert; Howard, David; Racanelli, Marco

    2012-06-01

    Increasingly complex specifications for next-generation focal plane arrays (FPAs) require smaller pixels, larger array sizes, reduced power consumption and lower cost. We have previously reported on the favorable features available in the commercially available TowerJazz CA18 0.18μm mixed-signal CMOS technology platform for advanced read-out integrated circuit (ROIC) applications. In his paper, new devices in development for commercial purposes and which may have applications in advanced ROICs are reported. First, results of buried-channel 3.3V field effect transistors (FETs) are detailed. The buried-channel pFETs show flicker (1/f) noise reductions of ~5X in comparison to surface-channel pFETs along with a significant reduction of the body constant parameter. The buried-channel nFETs show ~2X reduction of 1/f noise versus surface-channel nFETs. Additional reduced threshold voltage nFETs and pFETs are also described. Second, a high-density capacitor solution with a four-stacked linear (metal-insulator-metal) MIM capacitor having capacitance density of 8fF/μm2 is reported. Additional stacking with MOS capacitor in a 5V tolerant process results in >50fC/μm2 charge density. Finally, one-time programmable (OTP) and multi-time programmable (MTP) non-volatile memory options in the CA18 technology platform are outlined.

  14. Integrating commercial software in accelerator control- case study

    International Nuclear Information System (INIS)

    Pace, Alberto

    1994-01-01

    Using existing commercial software is the dream of any control system engineer for the development cost reduction that can reach one order of magnitude. This dream often vanishes when appears the requirement to have a uniform and consistent architecture through a wide number of components and applications. This makes it difficult to integrate several commercial packages that often impose different user interface and communication standards. This paper will describe the approach and standards that have been chosen for the CERN ISOLDE control system that have allowed several commercial packages to be integrated in the system as-they-are permitting the software development cost to be reduced to a minimum. (author). 10 refs., 2 tabs., 9 figs

  15. Commercial objectives, technology transfer, and systems analysis for fusion power development

    Science.gov (United States)

    Dean, Stephen O.

    1988-03-01

    Fusion is an essentially inexhaustible source of energy that has the potential for economically attractive commercial applications with excellent safety and environmental characteristics. The primary focus for the fusion-energy development program is the generation of centralstation electricity. Fusion has the potential, however, for many other applications. The fact that a large fraction of the energy released in a DT fusion reaction is carried by high-energy neutrons suggests potentially unique applications. These include breeding of fissile fuels, production of hydrogen and other chemical products, transmutation or “burning” of various nuclear or chemical wastes, radiation processing of materials, production of radioisotopes, food preservation, medical diagnosis and medical treatment, and space power and space propulsion. In addition, fusion R&D will lead to new products and new markets. Each fusion application must meet certain standards of economic and safety and environmental attractiveness. For this reason, economics on the one hand, and safety and environment and licensing on the other hand, are the two primary criteria for setting long-range commercial fusion objectives. A major function of systems analysis is to evaluate the potential of fusion against these objectives and to help guide the fusion R&D program toward practical applications. The transfer of fusion technology and skills from the national laboratories and universities to industry is the key to achieving the long-range objective of commercial fusion applications.

  16. Collateral circulation as a marker of the presence of viable myocardium in patients with recent myocardial infarction

    International Nuclear Information System (INIS)

    Fujita, M.; Ohno, A.; Wada, O.; Miwa, K.; Nozawa, T.; Yamanishi, K.; Sasayama, S.

    1991-01-01

    The relationship between the presence of viable myocardium and the extent of coronary collateral circulation to the infarct area was evaluated in 20 patients with a recent anterior myocardial infarction who had complete obstruction of the left anterior descending coronary artery. The viability of myocardial tissue was assessed by exercise thallium-201 myocardial scintigraphy, and the collateral circulation was angiographically evaluated by means of a collateral index ranging from 0 to 3. Patients were divided into two groups according to the presence (group 1, n = 10) or absence (group 2, n = 10) of viable myocardium in the perfusion territory of the infarct-related artery. The collateral index in group 1 was 2.5 ± 0.5 (SD), which was significantly higher than the 0.7 ± 0.8 in group 2. These findings indicate that the presence of ischemic but viable myocardium is intimately related to the development of collateral circulation in patients with myocardial infarction, and the existence of well-developed collateral channels predicts the presence of viable myocardium in the infarct area

  17. Evaluation of commercial and sulfated ZrO{sub 2} aiming application catalysis; Avaliacao de ZrO{sub 2} comercial e sulfatada visando aplicacao em catalise

    Energy Technology Data Exchange (ETDEWEB)

    Silva, F.N.; Dantas, J.; Costa, A.C.F.M., E-mail: nilson.s@hotmail.com [Universidade Federal de Campina Grande (UFCG), PB (Brazil). Pos-Graduacao em Engenharia de Materiais; Pallone, E.M.J.A. [Universidade de Sao Paulo (USP), Pirassununga, SP (Brazil). Departamento de Ciencias Basicas; Dutra, R.C.L. [Instituto de Aeronautica e Espaco (AQI/IAE), Sao Jose dos Campos, SP (Brazil). Divisao de Quimica

    2014-07-01

    This study evaluates the performance of commercial and sulfated ZrO{sub 2} for future application in catalysis. Commercial ZrO{sub 2} was provided by the company Saint-Gobain Zirpro. The sulfation occurred with SO{sub 4}{sup -2} ion content of 30% compared to the mass of ZrO{sub 2}. The samples were characterized by XRD, FTIR, EDX and GD. The results revealed the formation of a monoclinic phase for the commercial sample, and a monoclinic major phase with tetragonal traces for the sulfated sample. The commercial ZrO{sub 2} showed a narrow, bimodal and asymmetric agglomerates distribution, while the sulfated sample showed a narrow, tetramodal and asymmetric agglomerates distribution. The presence of traces of the tetragonal phase in the SO{sub 4}{sup -2}/ZrO{sub 2} XRD, and the presence of SO{sub 3} in the EDX were good indicators for future use in catalysis to provide ester. (author)

  18. Fate of viable but non-culturable Listeria monocytogenes in pig manure microcosms

    Directory of Open Access Journals (Sweden)

    Jeremy eDesneux

    2016-03-01

    Full Text Available The fate of two strains of L. monocytogenes and their ability to become viable but non-culturable (VBNC was investigated in microcosms containing piggery effluents (two raw manures and two biologically treated manures stored for two months at 8°C and 20°C. Levels of L. monocytogenes were estimated using the culture method, qPCR, and propidium monoazide treatment combined with qPCR (qPCRPMA. The chemical composition and the microbial community structure of the manures were also analysed. The strains showed similar decline rates and persisted up to 63 days. At day zero, the percentage of VBNC cells among viable cells was higher in raw manures (81.5-94.8% than in treated manures (67.8-79.2%. The changes in their proportion over time depended on the temperature and on the type of effluent: the biggest increase was observed in treated manures at 20°C and the smallest increase in raw manures at 8°C. The chemical parameters had no influence on the behaviour of the strains, but decrease of the persistence of viable cells was associated with an increase in the microbial richness of the manures. This study demonstrated that storing manure altered the culturability of L. monocytogenes, which rapidly entered the VBNC state, and underlines the importance of including VBNC cells when estimating the persistence of the pathogens in farm effluents.

  19. Monitoring of viable airborne SARS virus in ambient air

    Science.gov (United States)

    Agranovski, Igor E.; Safatov, Alexander S.; Pyankov, Oleg V.; Sergeev, Alexander N.; Agafonov, Alexander P.; Ignatiev, Georgy M.; Ryabchikova, Elena I.; Borodulin, Alexander I.; Sergeev, Artemii A.; Doerr, Hans W.; Rabenau, Holger F.; Agranovski, Victoria

    Due to recent SARS related issues (Science 300 (5624) 1394; Nature 423 (2003) 240; Science 300 (5627) 1966), the development of reliable airborne virus monitoring procedures has become galvanized by an exceptional sense of urgency and is presently in a high demand (In: Cox, C.S., Wathers, C.M. (Eds.), Bioaerosols Handbook, Lewis Publishers, Boca Raton, FL, 1995, pp. 247-267). Based on engineering control method (Aerosol Science and Technology 31 (1999) 249; 35 (2001) 852), which was previously applied to the removal of particles from gas carriers, a new personal bioaerosol sampler has been developed. Contaminated air is bubbled through porous medium submerged into liquid and subsequently split into multitude of very small bubbles. The particulates are scavenged by these bubbles, and, thus, effectively removed. The current study explores its feasibility for monitoring of viable airborne SARS virus. It was found that the natural decay of such virus in the collection fluid was around 0.75 and 1.76 lg during 2 and 4 h of continuous operation, respectively. Theoretical microbial recovery rates of higher than 55 and 19% were calculated for 1 and 2 h of operation, respectively. Thus, the new sampling method of direct non-violent collection of viable airborne SARS virus into the appropriate liquid environment was found suitable for monitoring of such stress sensitive virus.

  20. Dynamic partnership: A new approach to EM technology commercialization and deployment

    International Nuclear Information System (INIS)

    Daly, D.J.; Erickson, T.A.; Groenewold, G.H.

    1996-01-01

    The task of restoring nuclear defense complex sites under the U.S. Department of Energy (DOE) Environmental Management (EM) Program presents an unprecedented challenge to the environmental restoration community. Effective and efficient cleanup requires the timely development or modification of novel cleanup technologies applicable to radioactive wastes. Fostering the commercialization of these innovative technologies is the mission of EM-50, the EM Program Office of Science and Technology. However, efforts are often arrested at the open-quotes valley of death,close quotes the general term for barriers to demonstration, commercialization, and deployment. The Energy ampersand Environmental Research Center (EERC), a not-for-profit, contract-supported organization focused on research, development, demonstration, and commercialization (RDD ampersand C) of energy and environmental technologies, is in the second year of a cooperative agreement with the U.S. Department of Energy (DOE) Morgantown Energy Technology Center (METC) designed to deliver EM technologies into the commercial marketplace through a unique combination of technical support, real-world demonstration, and brokering. This paper profiles this novel approach, termed open-quotes Dynamic Partnership,close quotes and reviews the application of this concept to the ongoing commercialization and deployment of four innovative cleanup technologies. 2 tabs

  1. Risk mitigation process for utilization of commercial off-the-shelf (COTS) parts in CCD camera for military applications

    Science.gov (United States)

    Ahmad, Anees; Batcheldor, Scott; Cannon, Steven C.; Roberts, Thomas E.

    2002-09-01

    This paper presents the lessons learned during the design and development of a high performance cooled CCD camera for military applications utilizing common commercial off the shelf (COTS) parts. Our experience showed that concurrent evaluation and testing of high risk COTS must be performed to assess their performance over the required temperature range and other special product requirements such as fuel vapor compatibility, EMI and shock susceptibility, etc. Technical, cost and schedule risks for COTS parts must also be carefully evaluated. The customer must be involved in the selection and evaluation of such parts so that the performance limitations of the selected parts are clearly understood. It is equally important to check with vendors on the availability and obsolescence of the COTS parts being considered since the electronic components are often replaced by newer, better and cheaper models in a couple of years. In summary, this paper addresses the major benefits and risks associated with using commercial and industrial parts in military products, and suggests a risk mitigation approach to ensure a smooth development phase, and predictable performance from the end product.

  2. The commercial application prospect of HTGR plant in China

    International Nuclear Information System (INIS)

    Wang Yingsu

    2008-01-01

    With an introduction of the features and current situation of the HTGR power generation as well as the development of HTGR demonstration project in China, the article analyzes the necessity of developing HTGR power plants. The article proposes to exercise the advantages of HTGR to full extent so as to further develop HTGR power plants. It is believed that HTGR is of great commercial promotion value under appropriate circumstances. (authors)

  3. Roots of success: cultivating viable community forestry

    Energy Technology Data Exchange (ETDEWEB)

    MacQueen, Duncan

    2009-05-15

    Is community forestry emerging from the shadows? The evidence shows that locally controlled enterprises can be economically viable, and often build on stronger social and environmental foundations than the big private-sector players. Certainly this is an industry in need of a shakeup. Many forests have become flashpoints where agro-industry, large-scale logging concerns and conservation interests clash, while forest-dependent communities are left out in the cold. Meanwhile, governments – driven by concerns over the climate impacts of deforestation – are having to gear up for legal, sustainable forestry production. Community forestry could be crucial to solving many of these challenges. By building on local core capabilities and developing strategic partnerships, they are forging key new business models that could transform the sector.

  4. Application of geographical information systems for the optimal location of a commercial network

    Directory of Open Access Journals (Sweden)

    Vicente Rodríguez

    2017-07-01

    Full Text Available Purpose - The purpose of this paper is to study the optimization of the geographical location of a network of points of sale, so that each retailer can have access to a potential geographic market. In addition, the authors study the importance of the distance variable in the commercial viability of a point of sale and a network of points of sale, analysing if the best location for each point (local optimum is always the best location for the whole (global optimum. Design/methodology/approach - Location-allocation models are applied using p-median algorithms and spatial competition maximization to analyse the actual journeys of 64,740 car buyers in 1240 postal codes using a geographic information system (GIS and geomarketing techniques. Findings - The models show that the pursuit of individual objectives by each concessionaire over the collective provides poorer results for the whole network of points of sale when compared to coordinated competition. The solutions provided by the models considering geographic and marketing criteria permit a reduction in the length of journeys made by the buyers. GIS allows the optimal control of market demand coverage through the collaborative strategies of the supplying retailers, in this case, car dealerships. Originality/value - The paper contributes to the joint research of geography and marketing from a theoretical and practical point of view. The main contribution is the use of information on actual buyer journeys for the optimal location of a network of points of sale. This research also contributes to the analysis of the correlation between the optimum local and optimum global locations of a commercial network and is a pioneering work in the application of these models to the automotive sector in the territorial area of the study.

  5. Density functional studies of functionalized graphitic materials with late transition metals for oxygen reduction reactions

    DEFF Research Database (Denmark)

    Vallejo, Federico Calle; Martinez, Jose Ignacio; Rossmeisl, Jan

    2011-01-01

    Low-temperature fuel cells are appealing alternatives to the conventional internal combustion engines for transportation applications. However, in order for them to be commercially viable, effective, stable and low-cost electrocatalysts are needed for the Oxygen Reduction Reaction (ORR) at the ca...

  6. Development of a low commercial value fish-sausage from the fish trawling “mix” category

    Directory of Open Access Journals (Sweden)

    Juliana de Lima Brandão GUIMARÃES

    2018-05-01

    Full Text Available Abstract The decreasing stock of the main species consumed in Brazil has stimulated studies regarding the use and development of products using low commercial value species. The shrimp trawling modality produces a large volume of a “mix” category comprising low commercial value fish. However, it is necessary to develop products with greater practicality to meet the current demands of the Brazilian consumer. The aim of the present study was to develop a sausage using a low commercial value fish, the Brazilian flathead (Percophis brasiliensis , caught in the fish trawling “mix” category landed in Niterói/RJ, and perform physico-chemical, microbiological, toxicological and sensorial analyses. The centesimal composition of the analyzed fish were as follows: humidity 73.78%, proteins 16.17%, carbohydrates 3.75%, total lipids 4.41% and ash 1.78%. The microbiological and toxicological results were within the legislation standards. Twenty varieties of fatty acids (AG were detected, with the most frequent being palmitic acid (22.81%. Among the omega-3 series, the most frequent were eicosapentaenoic acid (5.36% and docosahexaenoic acid (15.95%. Regarding minerals, the most noteworthy were sodium, calcium and iron (1114.24 mg, 112.32 mg and 1.73 mg respectively. The sausage showed 87.30% acceptability. The results demonstrate that the low commercial value fish Brazilian flathead resulted in a viable product for use in fish technology, with excellent nutritional results.

  7. Commercial management and competition relationship in industrial and agroindustrial SMEs in Tundama, Colombia

    Directory of Open Access Journals (Sweden)

    Luis Felipe Rodríguez C

    2012-08-01

    Full Text Available The process of freeing trade that has been occurring in the country since the late twentieth century has uncovered a number of weaknesses and threats facing our business organizations these days, in particular for small and medium enterprises (SME. The overall objective of this research is to analyze the relationship between the Commercial Management system and competitiveness of industrial and agroindustrial SM Es in Tundama, Colombia, in order to generate viable recommendations to give these business organizations competitive advantages; the methodology used was based on a descriptive non-experimental methodology design. Notably, the business organizations studied in this research have high transaction costs when accessing input markets and services, which constitute a major obstacle to advancing technology adoption

  8. Application of Best Industry Practices to the Design of Commercial Refrigerators

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-06-30

    The substantial efficiency improvements which have been realized in residential refrigerators over the last twenty years due to implementation of the National Appliance Energy Conservation Act and changing consumer reactions to energy savings give an indication of the potential for improvement in the commercial sector, where few such efficiency improvements have been made to date. The purchase decision for commercial refrigerators is still focused primarily on first cost and product performance issues such as maximizing storage capacity, quick pulldown, durability, and reliability. The project applied techniques used extensively to reduce energy use in residential refrigeration to a commercial reach-in refrigerator. The results will also be applicable to other commercial refrigeration equipment, such as refrigerated vending machines, reach-in freezers, beverage merchandisers, etc. The project described in this paper was a collaboration involving the Appliance and Building Technology Sector of TIAX, the Delfield Company, and the U. S. Department of Energy's Office of Building Technologies. Funding was provided by DOE through Cooperative Agreement No. DE-FC26-00NT41000. The program plan and schedule were structured to assure successful integration of the TIAX work on development of efficient design concepts into Delfield's simultaneous development of the Vantage product line. The energy-saving design options evaluated as part of the development included brushless DC and PSC fan motors, high-efficiency compressors, variable-speed compressor technology, cabinet thermal improvement (particularly in the face frame area), increased insulation thickness, a trap for the condensate line, improved insulation, reduced-wattage antisweat heaters, non-electric antisweat heating, off-cycle defrost termination, rifled heat exchanger tubing, and system optimization (selection of heat exchangers, fans, and subcooling, superheat, and suction temperatures for efficient

  9. Mapping In Vivo Tumor Oxygenation within Viable Tumor by 19F-MRI and Multispectral Analysis

    Directory of Open Access Journals (Sweden)

    Yunzhou Shi

    2013-11-01

    Full Text Available Quantifying oxygenation in viable tumor remains a major obstacle toward a better understanding of the tumor microenvironment and improving treatment strategies. Current techniques are often complicated by tumor heterogeneity. Herein, a novel in vivo approach that combines 19F magnetic resonance imaging (19F-MRIR1 mapping with diffusionbased multispectral (MS analysis is introduced. This approach restricts the partial pressure of oxygen (pO2 measurements to viable tumor, the tissue of therapeutic interest. The technique exhibited sufficient sensitivity to detect a breathing gas challenge in a xenograft tumor model, and the hypoxic region measured by MS 19F-MRI was strongly correlated with histologic estimates of hypoxia. This approach was then applied to address the effects of antivascular agents on tumor oxygenation, which is a research question that is still under debate. The technique was used to monitor longitudinal pO2 changes in response to an antibody to vascular endothelial growth factor (B20.4.1.1 and a selective dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor (GDC-0980. GDC-0980 reduced viable tumor pO2 during a 3-day treatment period, and a significant reduction was also produced by B20.4.1.1. Overall, this method provides an unprecedented view of viable tumor pO2 and contributes to a greater understanding of the effects of antivascular therapies on the tumor's microenvironment.

  10. Study of the effects of proline, phenylalanine, and urea foliar application to Tempranillo vineyards on grape amino acid content. Comparison with commercial nitrogen fertilisers.

    Science.gov (United States)

    Garde-Cerdán, T; López, R; Portu, J; González-Arenzana, L; López-Alfaro, I; Santamaría, P

    2014-11-15

    The aim of this work was to study the influence of foliar application of different nitrogen sources on grape amino acid content. The nitrogen sources applied to Tempranillo grapevines were proline, phenylalanine, urea, and two commercial nitrogen fertilisers, both without and with amino acids in their formulations. All treatments were applied at veraison and one week later. Proline treatment did not affect the must nitrogen composition. However, phenylalanine and urea foliar application enhanced the plants' synthesis of most of the amino acids, producing similar effects. In addition, the spray of commercial nitrogen fertilisers over leaves also induced a rise in grape amino acid concentrations regardless of the presence or absence of amino acids in their formulation. The most effective treatments were phenylalanine and urea followed by nitrogen fertilisers. This finding is of oenological interest for improved must nitrogen composition, ensuring better fermentation kinetics and most likely enhancing wine quality. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. 2010 Hydrogen and Fuel Cell Global Commercialization & Development Update

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2010-11-01

    This report offers examples of real-world applications and technical progress of hydrogen and fuel cell technologies, including policies adopted by countries to increase technology development and commercialization.

  12. Emergency lighting for industrial, commercial and residential premises

    CERN Document Server

    Lyons, X

    2013-01-01

    Emergency Lighting: For Industrial, Commercial and Residential Premises concerns itself with the provision of emergency lighting to facilitate exit routes for people in industrial, commercial, and residential areas. The book covers important topics such as the objectives of emergency lighting systems; the identification of safe routes under low lighting in different areas; and related devices such as luminaires, emergency signs, and way-guidance. Also discussed are the applications of emergency lighting; factors to consider in the design of emergency lighting; electrical installations; and tes

  13. Viable group A streptococci in macrophages during acute soft tissue infection.

    Directory of Open Access Journals (Sweden)

    Pontus Thulin

    2006-03-01

    Full Text Available Group A streptococcal severe soft tissue infections, such as necrotizing fasciitis, are rapidly progressive infections associated with high mortality. Group A streptococcus is typically considered an extracellular pathogen, but has been shown to reside intracellularly in host cells.We characterized in vivo interactions between group A streptococci (GAS and cells involved in innate immune responses, using human biopsies (n = 70 collected from 17 patients with soft tissue infections. Immunostaining and in situ image analysis revealed high amounts of bacteria in the biopsies, even in those collected after prolonged antibiotic therapy. Viability of the streptococci was assessed by use of a bacterial viability stain, which demonstrated viable bacteria in 74% of the biopsies. GAS were present both extracellularly and intracellularly within phagocytic cells, primarily within macrophages. Intracellular GAS were predominantly noted in biopsies from newly involved tissue characterized by lower inflammation and bacterial load, whereas purely extracellular GAS or a combination of intra- and extracellular GAS dominated in severely inflamed tissue. The latter tissue was also associated with a significantly increased amount of the cysteine protease streptococcal pyrogenic exotoxin SpeB. In vitro studies confirmed that macrophages serve as reservoirs for viable GAS, and infection with a speB-deletion mutant produced significantly lower frequencies of cells with viable GAS following infection as compared to the wild-type bacteria.This is the first study to demonstrate that GAS survive intracellularly in macrophages during acute invasive infections. This intracellular presence may have evolved as a mechanism to avoid antibiotic eradication, which may explain our finding that high bacterial load is present even in tissue collected after prolonged intravenous antibiotic therapy. This new insight into the pathogenesis of streptococcal soft tissue infections

  14. Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection.

    Directory of Open Access Journals (Sweden)

    2006-01-01

    Full Text Available BACKGROUND: Group A streptococcal severe soft tissue infections, such as necrotizing fasciitis, are rapidly progressive infections associated with high mortality. Group A streptococcus is typically considered an extracellular pathogen, but has been shown to reside intracellularly in host cells. METHODS AND FINDINGS: We characterized in vivo interactions between group A streptococci (GAS and cells involved in innate immune responses, using human biopsies (n = 70 collected from 17 patients with soft tissue infections. Immunostaining and in situ image analysis revealed high amounts of bacteria in the biopsies, even in those collected after prolonged antibiotic therapy. Viability of the streptococci was assessed by use of a bacterial viability stain, which demonstrated viable bacteria in 74% of the biopsies. GAS were present both extracellularly and intracellularly within phagocytic cells, primarily within macrophages. Intracellular GAS were predominantly noted in biopsies from newly involved tissue characterized by lower inflammation and bacterial load, whereas purely extracellular GAS or a combination of intra- and extracellular GAS dominated in severely inflamed tissue. The latter tissue was also associated with a significantly increased amount of the cysteine protease streptococcal pyrogenic exotoxin SpeB. In vitro studies confirmed that macrophages serve as reservoirs for viable GAS, and infection with a speB-deletion mutant produced significantly lower frequencies of cells with viable GAS following infection as compared to the wild-type bacteria. CONCLUSIONS: This is the first study to demonstrate that GAS survive intracellularly in macrophages during acute invasive infections. This intracellular presence may have evolved as a mechanism to avoid antibiotic eradication, which may explain our finding that high bacterial load is present even in tissue collected after prolonged intravenous antibiotic therapy. This new insight into the pathogenesis

  15. Commercial integration and partnering at Savannah River Site

    Energy Technology Data Exchange (ETDEWEB)

    Steele, J.R. [Westinghouse Savannah River Co., Aiken, SC (United States); Babione, R.A.; Shikashio, L.A.; Wacaster, A.J.; Paterson, A.D. [SCIENTECH, Inc., Idaho Falls, ID (United States)

    1994-06-01

    Savannah River Site (SRS), particularly the Savannah River Technology Center (SRTC) with the experience from the first successful Integrated Technology Demonstration, can provide an excellent foundation for meeting DOE-EM`s objectives with the new DOE-EM five focus area approach. With this in mind, SRTC established an activity to pursue full commercialization of environmental technologies. This report is an assessment of the status of commercialization at SRS and provides recommendations for enhancement as well as some tools critical to implementation. A review was made of the current situation at SRS with regards to taking technology development to commercial fruition. This was done from the perspective of comparing it to known commercialization models and processes. It was found that SRTC already works through many of the steps in these processes. With integration and action-oriented efforts of the inclusion of business and market factors, SRTC could become an aggressive, successful developer of commercialized technologies. Commercial success criteria tools were developed with regards to integrating them with SRTC selection criteria to ensure that all critical factors are covered in technology commercialization project evaluations. Private investors are very clear that their interest lies in funding commercial enterprises, not merely technologies. Mobilizing private capital is critical to real job growth and long-term economic development. Also, potential industry partners were identified that are willing to be involved with SRS` technology applications and regional development efforts. As another important component to success, regional support organizations were reviewed and evaluated.

  16. Commercial lumber

    Science.gov (United States)

    Kent A. McDonald; David E. Kretschmann

    1999-01-01

    In a broad sense, commercial lumber is any lumber that is bought or sold in the normal channels of commerce. Commercial lumber may be found in a variety of forms, species, and types, and in various commercial establishments, both wholesale and retail. Most commercial lumber is graded by standardized rules that make purchasing more or less uniform throughout the country...

  17. Conceptual design of a hybrid KrF laser system for ICF commercial applications

    International Nuclear Information System (INIS)

    Harris, D.B.; Lowenthal, D.D.

    1986-01-01

    KrF lasers appear to be the most efficient lasers operating near the optimal wavelength for laser fusion. Most high-efficiency, low-cost KrF laser designs use large electron-beam-driven amplifiers and use pure angular multiplexing for the required pulse compression. A recent study carried out by Los Alamos National Lab. and Spectra Technology has defied a high-efficiency hybrid KrF laser system architecture that uses both angular multiplexing and Raman beam combination. The high overall system efficiency of this hybrid design, ∼ 12%, is achieved primarily through the use of electron-beam sustained discharge lasers (EBSDL), and by using the efficient forward rotational Raman process in hydrogen. The new system appears attractive as a commercial-applications driver because the calculated efficiency is higher than the usual large electron-beam-pumped (EBP) KrF laser/pure angular multiplexing approach. In this paper, the hybrid system architecture will be described, and the trade-offs with respect to the large EBP amplifier/angular multiplexed system will be discussed

  18. 19 CFR 113.67 - Commercial gauger and commercial laboratory bond conditions.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Commercial gauger and commercial laboratory bond... SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Customs Bond Conditions § 113.67 Commercial gauger and commercial laboratory bond conditions. Commercial Gauger Bond Conditions (a) Commercial gauger bond...

  19. Biocatalytic Synthesis of the Rare Sugar Kojibiose: Process Scale-Up and Application Testing.

    Science.gov (United States)

    Beerens, Koen; De Winter, Karel; Van de Walle, Davy; Grootaert, Charlotte; Kamiloglu, Senem; Miclotte, Lisa; Van de Wiele, Tom; Van Camp, John; Dewettinck, Koen; Desmet, Tom

    2017-07-26

    Cost-efficient (bio)chemical production processes are essential to evaluate the commercial and industrial applications of promising carbohydrates and also are essential to ensure economically viable production processes. Here, the synthesis of the naturally occurring disaccharide kojibiose (2-O-α-d-glucopyranosyl-d-glucopyranoside) was evaluated using different Bifidobacterium adolescentis sucrose phosphorylase variants. Variant L341I_Q345S was found to efficiently synthesize kojibiose while remaining fully active after 1 week of incubation at 55 °C. Process optimization allowed kojibiose production at the kilogram scale, and simple but efficient downstream processing, using a yeast treatment and crystallization, resulted in more than 3 kg of highly pure crystalline kojibiose (99.8%). These amounts allowed a deeper characterization of its potential in food applications. It was found to have possible beneficial health effects, including delayed glucose release and potential to trigger SCFA production. Finally, we compared the bulk functionality of highly pure kojibiose to that of sucrose, hereby mapping its potential as a new sweetener in confectionery products.

  20. Maize Residue as a Viable Substrate for Farm Scale Cultivation of Oyster Mushroom (Pleurotus ostreatus

    Directory of Open Access Journals (Sweden)

    Abena O. Adjapong

    2015-01-01

    Full Text Available In the search for alternatives to sawdust as growing media in commercial mushroom cultivation, three organic substrates obtainable as crop residue, maize husk, maize cob, and maize stalk, with each being supplemented with rice bran, were evaluated as growth media for the oyster mushroom, Pleurotus ostreatus (Kummer. For the tested alternatives to sawdust, the harvested weight of fruiting bodies that sprouted on a kilogram maize husk media per crop (32.99 g was the highest. Sawdust media supported significantly (P<0.001 heavier fruiting bodies (42.18 than the maize residues. The peak mushroom harvests for the various substrates were obtained between the first and seventh fruiting body flushes. The biological efficiency of the substrates, which measured usable nutrients indicated that maize stalk supplemented with rice bran, was 39% compared to that of the sawdust media (60%. The maize husk media and the maize cob media had biological efficiencies of 32% and 9.5%, respectively. These results indicate that two of the tested growing media (maize stalk or husk produced mushrooms with yield characteristics that were comparable to the well-used sawdust in the cultivation of oyster mushrooms. The environmental and economic parameters involved in the use and carting of sawdust make these on-farm crop residues a viable alternative for mushroom cultivation in especially nonforest zones of Ghana.

  1. Open Search Environments: The Free Alternative to Commercial Search Services

    Directory of Open Access Journals (Sweden)

    Adrian O'Riordan

    2014-06-01

    Full Text Available Open search systems present a free and less restricted alternative to commercial search services. This paper explores the space of open search technology looking in particular at the issue of interoperability. A description of current protocols and formats for engineering open search applications is presented. The suitability of these technologies and issues around their adoption and operation are discussed. This open search approach is especially proving a fitting choice in applications involving the harvesting of resources and information integration. Principal among the technological solutions are OpenSearch and SRU. OpenSearch and SRU implement a federated model to enable existing and new search engines and search clients communicate. Applications and instances where Opensearch and SRU can be combined are presented. Other relevant technologies such as OpenURL, Apache Solr, and OAI-PMH are also discussed. The deployment of these freely licensed open standards in digital library applications is now a genuine alternative to commercial or proprietary systems.

  2. Hardness variability in commercial technologies

    International Nuclear Information System (INIS)

    Shaneyfelt, M.R.; Winokur, P.S.; Meisenheimer, T.L.; Sexton, F.W.; Roeske, S.B.; Knoll, M.G.

    1994-01-01

    The radiation hardness of commercial Floating Gate 256K E 2 PROMs from a single diffusion lot was observed to vary between 5 to 25 krad(Si) when irradiated at a low dose rate of 64 mrad(Si)/s. Additional variations in E 2 PROM hardness were found to depend on bias condition and failure mode (i.e., inability to read or write the memory), as well as the foundry at which the part was manufactured. This variability is related to system requirements, and it is shown that hardness level and variability affect the allowable mode of operation for E 2 PROMs in space applications. The radiation hardness of commercial 1-Mbit CMOS SRAMs from Micron, Hitachi, and Sony irradiated at 147 rad(Si)/s was approximately 12, 13, and 19 krad(Si), respectively. These failure levels appear to be related to increases in leakage current during irradiation. Hardness of SRAMs from each manufacturer varied by less than 20%, but differences between manufacturers are significant. The Qualified Manufacturer's List approach to radiation hardness assurance is suggested as a way to reduce variability and to improve the hardness level of commercial technologies

  3. The Potential Uses of Commercial Satellite Imagery in the Middle East

    Energy Technology Data Exchange (ETDEWEB)

    Vannoni, M.G.

    1999-06-08

    It became clear during the workshop that the applicability of commercial satellite imagery to the verification of future regional arms control agreements is limited at this time. Non-traditional security topics such as environmental protection, natural resource management, and the development of infrastructure offer the more promising applications for commercial satellite imagery in the short-term. Many problems and opportunities in these topics are regional, or at least multilateral, in nature. A further advantage is that, unlike arms control and nonproliferation applications, cooperative use of imagery in these topics can be done independently of the formal Middle East Peace Process. The value of commercial satellite imagery to regional arms control and nonproliferation, however, will increase during the next three years as new, more capable satellite systems are launched. Aerial imagery, such as that used in the Open Skies Treaty, can also make significant contributions to both traditional and non-traditional security applications but has the disadvantage of requiring access to national airspace and potentially higher cost. There was general consensus that commercial satellite imagery is under-utilized in the Middle East and resources for remote sensing, both human and institutional, are limited. This relative scarcity, however, provides a natural motivation for collaboration in non-traditional security topics. Collaborations between scientists, businesses, universities, and non-governmental organizations can work at the grass-roots level and yield contributions to confidence building as well as scientific and economic results. Joint analysis projects would benefit the region as well as establish precedents for cooperation.

  4. Commercial nuclear power: Assuring safety for the future

    International Nuclear Information System (INIS)

    Ramsey, C.B.; Modarres, M.

    1998-03-01

    This timely book offers insights into the benefits of nuclear power as well as the technological and environmental challenges facing the nuclear industry. Containing the results of worldwide scientific studies and industrial site visits, the book represents a timely focus on the applications of commercial nuclear power, the potential benefits to be gained from contained nuclear use, the environmental risks of nuclear power, and the prevention of nuclear accidents.This timely book offers insights into the benefits of nuclear power as well as the technological and environmental challenges facing the nuclear industry. Containing the results of worldwide scientific studies and industrial site visits, the book represents a timely focus on the applications of commercial nuclear power, the potential benefits to be gained from contained nuclear use, the environmental risks of nuclear power, and the prevention of nuclear accidents

  5. Advanced Analysis to Distinguish between Physical Decrease and Inactivation of Viable Phages in Aerosol by Quantitating Phage-Specific Particles.

    Science.gov (United States)

    Shimasaki, Noriko; Nojima, Yasuhiro; Sakakibara, Masaya; Kikuno, Ritsuko; Iizuka, Chiori; Okaue, Akira; Okuda, Shunji; Shinohara, Katsuaki

    2018-01-01

     Recent studies have investigated the efficacy of air-cleaning products against pathogens in the air. A standard method to evaluate the reduction in airborne viruses caused by an air cleaner has been established using a safe bacteriophage instead of pathogenic viruses; the reduction in airborne viruses is determined by counting the number of viable airborne phages by culture, after operating the air cleaner. The reduction in the number of viable airborne phages could be because of "physical decrease" or "inactivation". Therefore, to understand the mechanism of reduction correctly, an analysis is required to distinguish between physical decrease and inactivation. The purpose of this study was to design an analysis to distinguish between the physical decrease and inactivation of viable phi-X174 phages in aerosols. We established a suitable polymerase chain reaction (PCR) system by selecting an appropriate primer-probe set for PCR and validating the sensitivity, linearity, and specificity of the primer-probe set to robustly quantify phi-X174-specific airborne particles. Using this quantitative PCR system and culture assay, we performed a behavior analysis of the phage aerosol in a small chamber (1 m 3 ) at different levels of humidity, as humidity is known to affect the number of viable airborne phages. The results revealed that the reduction in the number of viable airborne phages was caused not only by physical decrease but also by inactivation under particular levels of humidity. Our study could provide an advanced analysis to differentiate between the physical decrease and inactivation of viable airborne phages.

  6. Estimating commercial property prices: an application of cokriging with housing prices as ancillary information

    Science.gov (United States)

    Montero-Lorenzo, José-María; Larraz-Iribas, Beatriz; Páez, Antonio

    2009-12-01

    A vast majority of the recent literature on spatial hedonic analysis has been concerned with residential property values, with only very few examples of studies focused on commercial property prices. The dearth of studies can be attributed to some of the challenges faced in the analysis of commercial properties, in particular the scarcity of information compared to residential transactions. In order to address this issue, in this paper we propose the use of cokriging and housing prices as ancillary information to estimate commercial property prices. Cokriging takes into account the spatial autocorrelation structure of property prices, and the use of more abundant information on housing prices helps to improve the accuracy of property value estimates. A case study of Toledo in Spain, a city for which commercial activity stemming from tourism is one of the key elements of the economy in the city, demonstrates that substantial accuracy and precision gains can be obtained from the use of cokriging.

  7. Reduced infectivity of waterborne viable but nonculturable Helicobacter pylori strain SS1 in mice.

    Science.gov (United States)

    Boehnke, Kevin F; Eaton, Kathryn A; Fontaine, Clinton; Brewster, Rebecca; Wu, Jianfeng; Eisenberg, Joseph N S; Valdivieso, Manuel; Baker, Laurence H; Xi, Chuanwu

    2017-08-01

    Helicobacter pylori infection has been consistently associated with lack of access to clean water and proper sanitation, but no studies have demonstrated that the transmission of viable but nonculturable (VBNC) H. pylori can occur from drinking contaminated water. In this study, we used a laboratory mouse model to test whether waterborne VBNCH. pylori could cause gastric infection. We performed five mouse experiments to assess the infectivity of VBNCH. pylori in various exposure scenarios. VBNC viability was examined using Live/Dead staining and Biolog phenotype metabolism arrays. High doses of VBNCH. pylori in water were chosen to test the "worst-case" scenario for different periods of time. One experiment also investigated the infectious capabilities of VBNC SS1 using gavage. Further, immunocompromised mice were exposed to examine infectivity among potentially vulnerable groups. After exposure, mice were euthanized and their stomachs were examined for H. pylori infection using culture and PCR methodology. VBNC cells were membrane intact and retained metabolic activity. Mice exposed to VBNCH. pylori via drinking water and gavage were not infected, despite the various exposure scenarios (immunocompromised, high doses) that might have permitted infection with VBNCH. pylori. The positive controls exposed to viable, culturable H. pylori did become infected. While other studies that have used viable, culturable SS1 via gavage or drinking water exposures to successfully infect mice, in our study, waterborne VBNC SS1 failed to colonize mice under all test conditions. Future studies could examine different H. pylori strains in similar exposure scenarios to compare the relative infectivity of the VBNC vs the viable, culturable state, which would help inform future risk assessments of H. pylori in water. © 2017 The Authors. Helicobacter Published by John Wiley & Sons Ltd.

  8. Use of commercial grade item dedication to reduce procurement costs

    International Nuclear Information System (INIS)

    Rosch, F.

    1995-01-01

    In the mid-1980s, the Nuclear Regulatory Industry (NRC) began inspecting utility practices of procuring and dedicating commercial grade items intended for plant safety-related applications. As a result of the industry efforts to address NRC concerns, nuclear utilities have enhanced existing programs and procedures for dedication of commercial grade items. Though these programs were originally enhanced to meet NRC concerns, utilities have discovered that the dedication of commercial grade items can also reduce overall procurement costs. This paper will discuss the enhancement of utility dedication programs and demonstrates how utilities have utilized them to reduce procurement costs

  9. Application of commercial RIA kit in investigating milk contamination with M1 aflatoxin

    International Nuclear Information System (INIS)

    Fukal, L.

    1988-01-01

    Measured were samples of commercially sold milk produced by two Czech dairies and samples of unprocessed cow's milk from three farms. The determination of aflatoxin M 1 in liquid milk was carried out with a RIA-test-aflatoxin M 1 B 1 kit. The range of the calibration curve of the kit is 0.06 to 2.0 μg/l. In samples of commercially sold milk a higher share of aflatoxin M 1 free samples was found (93%) and 7% samples contained 0.050 to 0.1 μg aflatoxin/l. The dilution effect was manifest in commercially sold milk. On the other hand in 7% samples of raw milk aflatoxin concentration exceeded the limits set by hygiene inspection bodies for consumption by infants. The detected aflatoxin concentrations are compared with data from abroad. (E.S.). 2 tabs., 13 refs

  10. Wood energy-commercial applications

    Science.gov (United States)

    Kennel, R. P.

    1978-01-01

    Wood energy is being widely investigated in many areas of the country because of the many obvious benefits of wood fuel such as the low price per million Btus relative to coal, oil, and gas; the wide availability of noncommercial wood and the proven ability to harvest it; established technology which is reliable and free of pollution; renewable resources; better conservation for harvested land; and the potential for jobs creation. The Southeastern United States has a specific leadership role in wood energy based on its established forest products industry experience and the potential application of wood energy to other industries and institutions. Significant questions about the widespread usage of wood energy are being answered in demonstrations around the country as well as the Southeast in areas of wood storage and bulk handling; high capitalization costs for harvesting and combustion equipment; long term supply and demand contracts; and the economic feasibility of wood energy outside the forest products industry.

  11. Entry of Vibrio harveyi and Vibrio fischeri into the viable but nonculturable state

    Digital Repository Service at National Institute of Oceanography (India)

    Ramaiah, Neelam; Ravel, J.; Straube, W.L.; Hill, R.T.; Colwell, R.R.

    , direct viable counts, actively respiring cell counts, nucleoid-containing cell counts, and total counts were determined. V. harveyi incubated at 22 degrees C nutrient-limited artificial seawater (ASW) became nonculturable after approximately 62 and 45 d...

  12. Improved identification of viable myocardium using second harmonic imaging during dobutamine stress echocardiography

    NARCIS (Netherlands)

    F. Sozzi (Fabiola); D. Poldermans (Don); J.J. Bax (Jeroen); A. Elhendy (Abdou); E.C. Vourvouri (Eleni); R. Valkema (Roelf); J. de Sutter; A.F.L. Schinkel (Arend); A. Borghetti; J.R.T.C. Roelandt (Jos)

    2001-01-01

    textabstractOBJECTIVE: To determine whether, compared with fundamental imaging, second harmonic imaging can improve the accuracy of dobutamine stress echocardiography for identifying viable myocardium, using nuclear imaging as a reference. PATIENTS: 30 patients with chronic left

  13. Changes in total viable count and TVB-N content in marinated chicken breast fillets during storage

    Science.gov (United States)

    Baltić, T.; Ćirić, J.; Velebit, B.; Petronijević, R.; Lakićević, B.; Đorđević, V.; Janković, V.

    2017-09-01

    Marination is a popular technique for enhancing meat properties. Depending on the marinade type and ingredients added, marination can improve sensory, chemical and microbiological quality of meat products. In this study, the total viable count and total volatile basic nitrogen (TVB-N) content in marinated chicken breast fillets were investigated. The possible correlation between bacterial growth and formation of TVB-N was also tested. Chicken breast fillets were immersed in a solution of table salt (as a control) orthree different marinades,which consisted of table salt, sodium tripolyphosphate and/or sodium citrate, and stored in air for nine days at 4±1°C. Analyses of the total viable count and TVB-N were performed on days0, 3, 6 and 9 day of storage. The total viable count gradually increased in all examined groups, and statistically significant differences (pchicken were significantly higher (pchicken marinated with sodium citrate was established (pchicken marinated with sodium tripolyphosphate.

  14. PossybliCom, a Commercially Viable Personal Navigator for Blind People

    Science.gov (United States)

    Bavaro, M.; Citterico, D.; Dionisio, C.; van Eijck, D.

    2007-08-01

    Disaps vof is a Dutch start-up Company which is born as spin-off from the Italian company Intecs S.p.A.. Disaps is working on a project called PossybliCom, which is the acronym of Positioning System for Blind, and it is developing wearable navigation equipment for visually impaired or in general people withself- localization problems. Other secondary markets could be thought of as well, such as peoplesuffering from Alzheimer or having temporary memory or consciousness losses. Even peoplehaving experienced problems like TIA (Transient Ischemic Attacks) or faints would need a highlyaccessible device knowing always the way home. PossybliCom is a contribution to further enhance these users' confidence in independent travelling by providing them with a more precise description of the surroundings they are in. A business feasibility study demonstrated how, under certain key restrictions on the system architecture,the product has a high potential for disabled people as well as for the others when specialenvironmental conditions apply. Main issues could be easily identified as accessibility, portability, ease of use, fast learning curve. The European Space Agency's business incubation facility ESI in Noordwijk is supporting the start-up project with physical incubation, which includes office space and shared facilities as well as access to services and the know-how of ESA staff. Once part of the business incubation programme, for aperiod of 6 months the company shall demonstrate the market feasibility and produce a detailed workplan for prototyping.

  15. Market potential for solar thermal energy supply systems in the United States industrial and commercial sectors: 1990--2030

    International Nuclear Information System (INIS)

    1991-12-01

    This report revises and extends previous work sponsored by the US DOE on the potential industrial market in the United States for solar thermal energy systems and presents a new analysis of the commercial sector market potential. Current and future industrial process heat demand and commercial water heating, space heating and space cooling end-use demands are estimated. The PC Industrial Model (PCIM) and the commercial modules of the Building Energy End-Use Model (BEEM) used by the DOE's Energy Information Administration (EIA) to support the recent National Energy Strategy (NES) analysis are used to forecast industrial and commercial end-use energy demand respectively. Energy demand is disaggregated by US Census region to account for geographic variation in solar insolation and regional variation in cost of alternative natural gas-fired energy sources. The industrial sector analysis also disaggregates demand by heat medium and temperature range to facilitate process end-use matching with appropriate solar thermal energy supply technologies. The commercial sector analysis disaggregates energy demand by three end uses: water heating, space heating, and space cooling. Generic conceptual designs are created for both industrial and commercial applications. Levelized energy costs (LEC) are calculated for industrial sector applications employing low temperature flat plate collectors for process water preheat; parabolic troughs for intermediate temperature process steam and direct heat industrial application; and parabolic dish technologies for high temperature, direct heat industrial applications. LEC are calculated for commercial sector applications employing parabolic trough technologies for low temperature water and space heating. Cost comparisons are made with natural gas-fired sources for both the industrial market and the commercial market assuming fuel price escalation consistent with NES reference case scenarios for industrial and commercial sector gas markets

  16. Large-scale distribution of tritium in a commercial product

    International Nuclear Information System (INIS)

    Combs, F.; Doda, R.J.

    1979-01-01

    Tritium enters the environment from various sources including nuclear reactor operations, weapons testing, natural production, and from the manufacture, use and ultimate disposal of commercial products containing tritium. A recent commercial application of tritium in the United States of America involves the backlighting of liquid crystal displays (LCD) in digital electronic watches. These watches are distributed through normal commercial channels to the general public. One million curies (MCi) of tritium were distributed in 1977 in this product. This is a significant quantity of tritium compared with power reactor-produced tritium (3MCi yearly) or with naturally produced tritium (6MCi yearly). This is the single largest commercial application involving tritium to date. The final disposition of tritium from large quantities of this product, after its useful life, must be estimated by considering the means of disposal and the possibility of dispersal of tritium concurrent with disposal. The most likely method of final disposition of this product will be disposal in solid refuse; this includes burial in land fills and incineration. Burial in land fills will probably contain the tritium for its effective lifetime, whereas incineration will release all the tritium gas (as the oxide) to the atmosphere. The use and disposal of this product will be studied as part of an environmental study that is at present being prepared for the U.S. Nuclear Regulatory Commission. (author)

  17. Fundamentals and commercial aspects of nanobiosensors in point-of-care clinical diagnostics.

    Science.gov (United States)

    Mahato, Kuldeep; Maurya, Pawan Kumar; Chandra, Pranjal

    2018-03-01

    Among various problems faced by mankind, health-related concerns are prevailing since long which are commonly found in the form of infectious diseases and different metabolic disorders. The clinical cure and management of such abnormalities are greatly dependent on the availability of their diagnoses. The conventional diagnostics used for such purposes are extremely powerful; however, most of these are limited by time-consuming protocols and require higher volume of test sample, etc. A new evolving technology called "biosensor" in this context shows an enormous potential for an alternative diagnostic device, which constantly compliments the conventional diagnoses. In this review, we have summarized different kinds of biosensors and their fundamental understanding with various state-of-the-art examples. A critical examination of different types of biosensing mechanisms is also reported highlighting the advantages of electrochemical biosensors for its great potentials in next-generation commercially viable modules. In recent years, a number of nanomaterials are extensively used to enhance not only the performance of biosensing mechanism, but also obtain robust, cheap, and fabrication-friendly durable mechanism. Herein, we have summarized the importance of nanomaterials in biosensing mechanism, their syntheses as well as characterization techniques. Subsequently, we have discussed the probe fabrication processes along with various techniques for assessing its analytical performances and potentials for commercial viability.

  18. Energy consumption and commercial applications of liquid foam insulation technology for greenhouses

    Energy Technology Data Exchange (ETDEWEB)

    Villeneuve, J. [Environnement-MJ, Quebec City, PQ (Canada); De Halleux, D. [Laval Univ., Quebec City, PQ (Canada). Dept. des Sols et de Genie Agroalimentaire; Aberkani, K. [Laval Univ., Quebec City, PQ (Canada). Centre de Recherche en Horticulture; Vineberg, S. [Sunarc of Canada, Montreal, PQ (Canada)

    2010-07-01

    Sunarc of Canada has developed an energy saving system for commercial greenhouse growers. Large amounts of energy are needed to operate commercial greenhouses in northern latitudes, and as energy prices fluctuate, it is important to enable growers to control their microclimate. Sunarc's liquid foam insulating system was installed in 2007 at 2 sites in Ontario. The first site had an area of 14,700 ft{sup 2} while the other site had an area of 43,000 ft{sup 2}. Both facilities were monitored for energy use during the winter period. Night-time energy savings ranged from above 60 per cent to below 10 per cent depending on outdoor temperatures. The greater savings occurred during colder outdoor temperatures. Monthly average night-time energy savings from February, March and April were 46.6, 42, and 32.3 per cent respectively. After initial commercial testing, the liquid foam system was re-engineered to optimize operations, reduce fill time, and improve liquid foam formulas. The new system was installed at a third site in Quebec as a demonstration unit. The company is currently negotiating international distribution rights with several partners.

  19. Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae.

    Science.gov (United States)

    Arraes, Maria Luisa Bezerra de Macedo; Holanda, Maísa Viana de; Lima, Luana Nepomuceno Gondim Costa; Sabadia, José Antônio Beltrão; Duarte, Cynthia Romariz; Almeida, Rosa Livia Freitas; Kendall, Carl; Kerr, Ligia Regina Sansigolo; Frota, Cristiane Cunha

    2017-12-01

    The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local population in five municipalities in the state of Ceará, northeastern Brazil. Samples were collected from 30 different sources. Viable bacilli were identified by reverse transcriptase polymerase chain reaction (PCR) of the M. leprae gyrA gene and sequencing of the PCR products. Physicochemical properties of each water source were also assessed. M. leprae gyrA mRNA was found in 23 (76.7%) of the water sources. No association was found between depth of the water and sample positivity, nor was there any association between the type of water used by the population and sample positivity. An association between viable M. leprae and temperature and pH was found. Georeferencing showed a relation between the residences of leprosy cases and water source containing the bacterium. The finding of viable M. leprae in natural water sources associated with human contact suggests that the environment plays an important role in maintaining endemic leprosy in the study region.

  20. 78 FR 773 - Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS...

    Science.gov (United States)

    2013-01-04

    ... Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial... Assistance (TAA) applicable to workers and former workers of Hartford Financial Services Group, Inc., Commercial/ Actuarial/Information Delivery Services (IDS)/Corporate & Financial Reporting group, Hartford...

  1. Delayed uptake and washout of contrast in non-viable infarcted myocardium shown with dynamic computed tomography

    DEFF Research Database (Denmark)

    Udholm, Sebastian; Laugesen, Sofie; Agger, Peter

    2014-01-01

    BACKGROUND: Assessment of ischemic but potentially viable myocardium plays an important role in the planning of coronary revascularization. Until now SPECT, PET, and MRI have been used to identify viable myocardium. Computed tomography (CT) is increasingly used to diagnose coronary atherosclerosis...... descending artery, followed by removal of the balloon and reperfusion. Four pigs died due to refractory ventricular fibrillation. After 6 weeks, dynamic cardiac CT was performed assessing both wall motion and contrast attenuation. Measurements of attenuation values in Hounsfield units (HU) in the infarct...

  2. The road to commercialization in Africa: lessons from developing the sickle-cell drug Niprisan.

    Science.gov (United States)

    Perampaladas, Kumar; Masum, Hassan; Kapoor, Andrew; Shah, Ronak; Daar, Abdallah S; Singer, Peter A

    2010-12-13

    Developing novel drugs from traditional medicinal knowledge can serve as a means to improve public health. Yet countries in sub-Saharan Africa face barriers in translating traditional medicinal knowledge into commercially viable health products. Barriers in moving along the road towards making a new drug available include insufficient manufacturing capacity; knowledge sharing between scientists and medical healers; regulatory hurdles; quality control issues; pricing and distribution; and lack of financing. The case study method was used to illustrate efforts to overcome these barriers during the development in Nigeria of Niprisan - a novel drug for the treatment of sickle cell anemia, a chronic blood disorder with few effective therapies. Building on the knowledge of a traditional medicine practitioner, Nigeria's National Institute for Pharmaceutical Research and Development (NIPRD) developed the traditional herbal medicine Niprisan. The commercialization of Niprisan reached a number of commercial milestones, including regulatory approval in Nigeria; securing US-based commercial partner XeChem; demonstrating clinical efficacy and safety; being awarded orphan drug status by the US Food and Drug Administration; and striking important relationships with domestic and international groups. Despite these successes, however, XeChem did not achieve mainstream success for Niprisan in Nigeria or in the United States. A number of reasons, including inconsistent funding and manufacturing and management challenges, have been put forth to explain Niprisan's commercial demise. As of this writing, NIPRD is considering options for another commercial partner to take the drug forward. Evidence from the Niprisan experience suggests that establishing benefit-sharing agreements, fostering partnerships with established research institutions, improving standardization and quality control, ensuring financial and managerial due diligence, and recruiting entrepreneurial leaders capable of

  3. The road to commercialization in Africa: lessons from developing the sickle-cell drug Niprisan

    Directory of Open Access Journals (Sweden)

    Daar Abdallah S

    2010-12-01

    Full Text Available Abstract Background Developing novel drugs from traditional medicinal knowledge can serve as a means to improve public health. Yet countries in sub-Saharan Africa face barriers in translating traditional medicinal knowledge into commercially viable health products. Barriers in moving along the road towards making a new drug available include insufficient manufacturing capacity; knowledge sharing between scientists and medical healers; regulatory hurdles; quality control issues; pricing and distribution; and lack of financing. The case study method was used to illustrate efforts to overcome these barriers during the development in Nigeria of Niprisan – a novel drug for the treatment of sickle cell anemia, a chronic blood disorder with few effective therapies. Discussion Building on the knowledge of a traditional medicine practitioner, Nigeria’s National Institute for Pharmaceutical Research and Development (NIPRD developed the traditional herbal medicine Niprisan. The commercialization of Niprisan reached a number of commercial milestones, including regulatory approval in Nigeria; securing US-based commercial partner XeChem; demonstrating clinical efficacy and safety; being awarded orphan drug status by the US Food and Drug Administration; and striking important relationships with domestic and international groups. Despite these successes, however, XeChem did not achieve mainstream success for Niprisan in Nigeria or in the United States. A number of reasons, including inconsistent funding and manufacturing and management challenges, have been put forth to explain Niprisan’s commercial demise. As of this writing, NIPRD is considering options for another commercial partner to take the drug forward. Summary Evidence from the Niprisan experience suggests that establishing benefit-sharing agreements, fostering partnerships with established research institutions, improving standardization and quality control, ensuring financial and managerial due

  4. Evaluation of respiratory route as a viable portal of entry for Salmonella in poultry

    Directory of Open Access Journals (Sweden)

    Kallapura G

    2014-08-01

    Full Text Available Gopala Kallapura,1 Xochitl Hernandez-Velasco,2 Neil R Pumford,1 Lisa R Bielke,1 Billy M Hargis,1 Guillermo Tellez1 1Department of Poultry Science, University of Arkansas, Fayetteville, AR, USA; 2College of Veterinary Medicine and Animal Husbandry, The National Autonomous University of Mexico, Mexico Abstract: With increasing reports of Salmonella infection, we are forced to question whether the fecal–oral route is the major route of infection and consider the possibility that airborne Salmonella infections might have a major unappreciated role. Today's large-scale poultry production, with densely stocked and enclosed production buildings, is often accompanied by very high concentrations of airborne microorganisms. Considering that the upper and lower respiratory lymphoid tissue requires up to 6 weeks to be fully developed, these immune structures seem to have a very minor role in preventing pathogen infection. In addition, the avian respiratory system in commercial poultry has anatomic and physiologic properties that present no challenge to the highly adapted Salmonella. The present review evaluates the hypothesis that transmission by the fecal–respiratory route may theoretically be a viable portal of entry for Salmonella in poultry. First, we update the current knowledge on generation of Salmonella bioaerosols, and the transport and fate of Salmonella at various stages of commercial poultry production. Further, emphasis is placed on survivability of Salmonella in these bioaerosols, as a means to assess the transport and subsequent risk of exposure and infection of poultry. Additionally, the main anatomic structures, physiologic functions, and immunologic defense in the avian respiratory system are discussed to understand the potential entry points inherent in each component that could potentially lead to infection and subsequent systemic infection of poultry by Salmonella. In this context, we also evaluate the role of the mucosal immune

  5. Senior health clinics: are they financially viable?

    Science.gov (United States)

    McAtee, Robin E; Crandall, Debra; Wright, Larry D; Beverly, Claudia J

    2009-07-01

    Are hospital-based outpatient interdisciplinary clinics a financially viable alternative for caring for our burgeoning population of older adults in America? Although highly popular, with high patient satisfaction rates among older adults and their families, senior health clinics (SHCs) can be expensive to operate, with limited quantifiable health outcomes. This study analyzed three geriatric hospital-based interdisciplinary clinics in rural Arkansas by examining their patient profiles, revenues, and expenses. It closely examined the effects of the downstream revenue using the multiplier effect and acknowledged other factors that weigh heavily on the success of SHCs and the care of older adults. The findings highlight the similarities and differences in the three clinics' operating and financial structures in addition to the clinics' and providers' productivity. The analysis presents an evidence-based illustration that SHCs can break even or lose large amounts of money.

  6. Health Information Technologies-Academic and Commercial Evaluation (HIT-ACE) methodology: description and application to clinical feedback systems.

    Science.gov (United States)

    Lyon, Aaron R; Lewis, Cara C; Melvin, Abigail; Boyd, Meredith; Nicodimos, Semret; Liu, Freda F; Jungbluth, Nathaniel

    2016-09-22

    Health information technologies (HIT) have become nearly ubiquitous in the contemporary healthcare landscape, but information about HIT development, functionality, and implementation readiness is frequently siloed. Theory-driven methods of compiling, evaluating, and integrating information from the academic and commercial sectors are necessary to guide stakeholder decision-making surrounding HIT adoption and to develop pragmatic HIT research agendas. This article presents the Health Information Technologies-Academic and Commercial Evaluation (HIT-ACE) methodology, a structured, theory-driven method for compiling and evaluating information from multiple sectors. As an example demonstration of the methodology, we apply HIT-ACE to mental and behavioral health measurement feedback systems (MFS). MFS are a specific class of HIT that support the implementation of routine outcome monitoring, an evidence-based practice. HIT-ACE is guided by theories and frameworks related to user-centered design and implementation science. The methodology involves four phases: (1) coding academic and commercial materials, (2) developer/purveyor interviews, (3) linking putative implementation mechanisms to hit capabilities, and (4) experimental testing of capabilities and mechanisms. In the current demonstration, phase 1 included a systematic process to identify MFS in mental and behavioral health using academic literature and commercial websites. Using user-centered design, implementation science, and feedback frameworks, the HIT-ACE coding system was developed, piloted, and used to review each identified system for the presence of 38 capabilities and 18 additional characteristics via a consensus coding process. Bibliometic data were also collected to examine the representation of the systems in the scientific literature. As an example, results are presented for the application of HIT-ACE phase 1 to MFS wherein 49 separate MFS were identified, reflecting a diverse array of characteristics

  7. Comparing different commercial zero valent iron nanoparticles to immobilize As and Hg in brownfield soil.

    Science.gov (United States)

    Gil-Díaz, M; Alonso, J; Rodríguez-Valdés, E; Gallego, J R; Lobo, M C

    2017-04-15

    Nanoscale zero valent iron (nZVI) particles obtained by different methods differ in their structure, which lead to different reactivity, and therefore a likely difference in the remediation efficiency. The present study compares the effectiveness of three commercial ZVI nanoparticles to immobilize As and Hg in two soils (A and B) collected from a brownfield highly contaminated by mining and metallurgy activities. Scarce data are available on the effectiveness of nZVI for Hg immobilization in soil. Two commercial nZVI slurries from Toda (RNIP and RNIP-D) and one from Nano Iron (25S) were used at different doses (1, 5 and 10%). The metal(loid) availability and mobility was evaluated with the TCLP test and Tessier extraction procedure. The influence of nZVI application on As and Hg speciation was also evaluated as well as its impact on soil pH, electrical conductivity and soil phytotoxicity to vetch germination. The three commercial nZVI particles significantly reduced As and Hg availability in the two soils studied, which led to a decrease in soil phytotoxicity. At the dose of 5% of nZVI a decrease of exchangeable-As higher than 70% was observed for both soils, whereas in the case of Hg, a higher dose of nZVI (10%) was necessary to achieve reductions of exchangeable-Hg between 63 and 90% depending on the type of nZVI and soil. No impact on soil pH and electrical conductivity was observed. The effectiveness of metal(loid) immobilization depended on type of nZVI, soil properties and metal(loid) characteristics. Nanoparticles from Nano Iron showed better results for As immobilization whereas RNIP nanoparticles were more effective for Hg. Overall, 25S at the dose of 5% resulted more effective than RNIP nanoparticles for the reduction of exchangeable-As (in the range of 6-14%), whereas RNIP and RNIP-D were 10 and 13% more effective, respectively, for the reduction of exchangeable-Hg at the dose of 10% in soil B. Thus, nZVI can be used for the remediation of highly As and

  8. Soft Robotics Commercialization: Jamming Grippers from Research to Product

    Science.gov (United States)

    Cheng, Nadia; Fakhouri, Sami; Culley, Bill

    2016-01-01

    Abstract Recent work in the growing field of soft robotics has demonstrated a number of very promising technologies. However, to make a significant impact in real-world applications, these new technologies must first transition out of the laboratory through successful commercialization. Commercialization is perhaps the most critical future milestone facing the field of soft robotics today, and this process will reveal whether the apparent impact we now perceive has been appropriately estimated. Since 2012, Empire Robotics has been one of the first companies to attempt to reach this milestone through our efforts to commercialize jamming-based robotic gripper technology in a product called VERSABALL®. However, in spring 2016 we are closing our doors, having not been able to develop a sustainable business around this technology. This article presents some of the key takeaways from the technical side of the commercialization process and lessons learned that may be valuable to others. We hope that sharing this information will provide a frame of reference for technology commercialization that can help others motivate research directions and maximize research impact. PMID:28078197

  9. Mathematical modelling of the viable epidermis: impact of cell shape and vertical arrangement

    KAUST Repository

    Wittum, Rebecca; Naegel, Arne; Heisig, Michael; Wittum, Gabriel

    2017-01-01

    In-silico methods are valuable tools for understanding the barrier function of the skin. The key benefit is that mathematical modelling allows the interplay between cell shape and function to be elucidated. This study focuses on the viable (living

  10. 75 FR 14609 - Commercial Fishing Industry Vessel Safety Advisory Committee; Vacancies

    Science.gov (United States)

    2010-03-26

    ... which Chapter 45 of Title 46, U.S.C. applies and persons representing the marine insurance industry... Industry Vessel Safety Advisory Committee; Vacancies AGENCY: Coast Guard, DHS. ACTION: Request for applications. SUMMARY: The Coast Guard seeks applications for membership on the Commercial Fishing Industry...

  11. Commercialization plan laser-based decoating systems

    International Nuclear Information System (INIS)

    Freiwald, J.; Freiwald, D.A.

    1998-01-01

    F2 Associates Inc. (F2) is a small, high-technology firm focused on developing and commercializing environmentally friendly laser ablation systems for industrial-rate removal of surface coatings from metals, concrete, and delicate substrates such as composites. F2 has a contract with the US Department of Energy Federal Energy Technology Center (FETC) to develop and test a laser-based technology for removing contaminated paint and other contaminants from concrete and metal surfaces. Task 4.1 in Phase 2 of the Statement of Work for this DOE contract requires that F2 ''document its plans for commercializing and marketing the stationary laser ablation system. This document shall include a discussion of prospects for commercial customers and partners and may require periodic update to reflect changing strategy. This document shall be submitted to the DOE for review.'' This report is being prepared and submitted in fulfillment of that requirement. This report describes the laser-based technology for cleaning and coatings removal, the types of laser-based systems that have been developed by F2 based on this technology, and the various markets that are emerging for this technology. F2's commercialization and marketing plans are described, including how F2's organization is structured to meet the needs of technology commercialization, F2's strategy and marketing approach, and the necessary steps to receive certification for removing paint from aircraft and DOE certification for D and D applications. The future use of the equipment built for the DOE contract is also discussed

  12. Using commercial amateur astronomical spectrographs

    CERN Document Server

    Hopkins, Jeffrey L

    2014-01-01

    Amateur astronomers interested in learning more about astronomical spectroscopy now have the guide they need. It provides detailed information about how to get started inexpensively with low-resolution spectroscopy, and then how to move on to more advanced  high-resolution spectroscopy. Uniquely, the instructions concentrate very much on the practical aspects of using commercially-available spectroscopes, rather than simply explaining how spectroscopes work. The book includes a clear explanation of the laboratory theory behind astronomical spectrographs, and goes on to extensively cover the practical application of astronomical spectroscopy in detail. Four popular and reasonably-priced commercially available diffraction grating spectrographs are used as examples. The first is a low-resolution transmission diffraction grating, the Star Analyser spectrograph. The second is an inexpensive fiber optic coupled bench spectrograph that can be used to learn more about spectroscopy. The third is a newcomer, the ALPY ...

  13. Economically viable biochemical processes for the advanced rural biorefinery and downstream recovery operations

    Science.gov (United States)

    Rural biorefineries offer an alternative to traditional ethanol production by providing the opportunity to produce fuel on site to reduce costs associated with biomass transportation thus making the fuel economically viable. Widespread installation of rural biorefineries could lead to increased upt...

  14. Protein Engineering: Case Studies of Commercialized Engineered Products

    Science.gov (United States)

    Walsh, Gary

    2007-01-01

    Programs in biochemistry invariably encompass the principles of protein engineering. Students often display increased understanding and enthusiasm when theoretical concepts are underpinned by practical example. Herein are presented five case studies, each focusing upon a commercial protein product engineered to enhance its application-relevant…

  15. Moving research to patient applications through commercialization: understanding and evaluating the role of intellectual property.

    Science.gov (United States)

    Patino, Robert M

    2010-03-01

    The advancement of research from discovery to the delivery of medical care can be limited without the support of industry to sponsor its continued development. Federal government financial support is generally crucial in early-stage development through funding from the NIH, National Science Foundation, and other federal agencies; however, government support generally stops shortly after basic research discoveries have been reported. Much of the cessation of financial support derives from the government's regulatory responsibilities, as sponsoring the commercialization of a product conflicts with regulation of the approval for clinical use of a drug or device. Furthermore, differences in goals, resources, and flexibility render government, as compared with private industry, inefficient and less responsive to market demands with regard to stream-lining the development of and enhancing the quality of products and services offered. Thus, industry and private investment provide the bridge that converts new discoveries into healthcare products that are available to consumers and patients. This conversion occurs through commercialization, which involves both high risks and high rewards. Taking advantage of the commercialization option for research development requires an understanding of the technology transfer process. This article reviews 5 topics: 1) industry motivation to invest in academic research; 2) institutional considerations in partnering with industry; 3) academia's interactions with inventors in the commercialization process; 4) the research institution's route to commercialization, and 5) the role of intellectual property and commercialization in the advancement of healthcare.

  16. Immunization against chlamydial genital infection in guinea pigs with UV-inactivated and viable chlamydiae administered by different routes

    International Nuclear Information System (INIS)

    Rank, R.G.; Batteiger, B.E.; Soderberg, L.S.

    1990-01-01

    Female guinea pigs were immunized with viable or UV light-inactivated chlamydiae, belonging to the species Chlamydia psittaci, by intravenous, subcutaneous, oral, or ocular routes. All animals were then inoculated vaginally with viable chlamydiae to determine the extent of protection against challenge infection induced by the various regimens. The course of genital infection was significantly reduced in intensity in all groups of animals except the unimmunized controls and those animals immunized orally with inactivated antigen. Guinea pigs immunized with viable antigen were more likely to develop resistance to challenge infection and, in general, had a significantly greater degree of protection than animals immunized with inactivated antigen. No one route seemed superior in producing a protective response. Animals in all groups demonstrating protection developed serum and secretion immunoglobulin G antibody responses to chlamydiae. Lymphocyte proliferative reactions to chlamydial antigen were variable among groups. Immunoblot analysis of serum and secretions indicated a wide range of antibody specificities, but most protected animals produced antibodies to the major outer membrane protein, lipopolysaccharide, and the 61-kilodalton protein. No definitive associations could be made between the increased ability of immunization with viable organisms to produce resistance to challenge infection and a particular immune parameter. These data indicate that viable chlamydiae given by various routes are able to induce a strong immune response which can provide resistance against reinfection in some cases or at least reduce the degree of infection to a greater degree than inactivated antigen. However, complete resistance to genital tract infection may be difficult to obtain and alternate immunizations strategies may have to be developed

  17. Space Station Workshop: Commercial Missions and User Requirements

    Science.gov (United States)

    1988-01-01

    The topics of discussion addressed during a three day workshop on commercial application in space are presented. Approximately half of the program was directed towards an overview and orientation to the Space Station Project; the technical attributes of space; and present and future potential commercial opportunities. The remaining time was spent addressing technological issues presented by previously-formed industry working groups, who attempted to identify the technology needs, problems or issues faced and/or anticipated by the following industries: extraction (mining, agriculture, petroleum, fishing, etc.); fabrication (manufacturing, automotive, aircraft, chemical, pharmaceutical and electronics); and services (communications, transportation and retail robotics). After the industry groups presented their technology issues, the workshop divided into smaller discussion groups composed of: space experts from NASA; academia; industry experts in the appropriate disciplines; and other workshop participants. The needs identified by the industry working groups, space station technical requirements, proposed commercial ventures and other issues related to space commercialization were discussed. The material summarized and reported are the consensus from the discussion groups.

  18. How Industry 4.0 Changes Business : A Commercial Perspective

    Directory of Open Access Journals (Sweden)

    Ayşe Göksu Özüdoğru

    2018-05-01

    Full Text Available Industry is the part of an economy that manufacture components and goods which are highly automatized. This paper presents a general understanding about the Fourth Industry Revolution- Industry 4.0 approach from a commercial point of view. Firstly, the history of Industrial Revolution is explained and the roadmap to Industry 4.0 is shown. Industry components and the main understanding of Industry 4.0 is explained through the previous studies. Secondly, the most common usage, implementation areas and the challenging points are demonstrated. Commercial and industrial application examples of Industry 4.0 in different sectors and the possible implementation areas are defined based on countries and sectors. Finally, the commercial impacts of this new business model is given from the industrial and human perspectives.

  19. 7 CFR 1942.111 - Applicant eligibility.

    Science.gov (United States)

    2010-01-01

    ... applicant apply to commercial sources for financing. To provide a basis for referral of only those applicants who may be able to finance projects through commercial sources, approval officials should maintain... must determine whether financing from commercial sources at reasonable rates and terms is available. If...

  20. Golden Genesis and the Teotonio Vilela Foundation: commercializing PV residential electrification with a not-for-profit partner

    Energy Technology Data Exchange (ETDEWEB)

    D' Addario, P.J. [International Fund for Renewable Energy and Energy Efficiency, New York, NY (United States)

    2000-11-01

    This article presents a case study of a project which provides photovoltaic-based rural electrification in the state of Alagoas in northeastern Brazil. The project, the Luz do Sol Programme (LdS), was initiated in mid-1996 by the Golden Genesis Company (Golden) and the Fundacao Teotonio Vilela (FTV). The article emphasizes some noteworthy characteristics of the project: the partnership between US commercial and Brazilian philanthropic interests; the financial aspect, a dedicated line of credit requiring only the equipment itself as security; and the local ownership and management of system operations, collections, and routine maintenance. In 1996, the Golden Genesis Company had developed a central battery charging system to bring the price of electrification within the range of the rural poor; it financed the US content of the systems, with the Bank of the Northeast of Brazil (BN) financing the Brazilian content. The article traces the long and arduous path to establish the programme, including both bureaucratic and technical challenges. These difficulties brought the project to an impasse in August of 1998, and Golden withdrew. FTV then re-negotiated the agreement with BN, changing the technical approach to individual solar home systems. This improved the situation, and the project has since enjoyed 100% loan repayment rates from the entrepreneurs. In June 1999, BP/Solarex became FTV's new commercial partner. The project currently shows promise of becoming the commercially viable programme originally envisaged by Golden, with commercial and technical decision-making at the local level. (author)

  1. Enabling Sustainable Exploration through the Commercial Development of Space

    Science.gov (United States)

    Nall, Mark; Casas, Joseph

    2003-01-01

    The commercial development of space offers enabling benefits to space exploration. This paper examines how those benefits can be realized, and how the Space Product Development Office of the National Aeronautics and Space Administration is taking the first steps towards opening the space frontier through vital and sustainable industrial development. The Space Product Development Office manages 15 Commercial Space Centers that partner with US industry to develop opportunities for commerce in space. This partnership directly benefits NASA exploration in four primary ways. First, by actively involving traditional and non-traditional companies in commercial space activities, it seeks and encourages to the maximum extent possible the fullest commercial use of space, as directed by NASA's charter. Second, the commercial research and technologies pursued and developed in the program often have direct applicability to NASA priority mission areas. This dual use strategy for research and technology has the potential to greatly expand what the NASA scientific community can do. Third, the commercial experiment hardware developed by the Commercial Space Centers and their industrial partners is available for use by NASA researchers in support of priority NASA research. By utilizing low cost and existing commercial hardware, essential NASA research can be more readily accomplished. Fourth, by assisting industry in understanding the use of the environment of space and in helping industry enhance the tools and technologies for NASA and commercial space systems, the market for commercial space utilization and the capability for meeting the future growing market needs is being developed. These two activities taken together form the beginning of a new space economy that will enable sustainable NASA exploration of the universe.

  2. Manipulating the percolation threshold of carbon nanotubes in polymeric composites

    NARCIS (Netherlands)

    Hermant, M.C.

    2009-01-01

    The latex-based technique to introduce carbon nanotubes (CNTs) into polymers has shown to be highly versatile and to produce conductive composites with low loadings of CNTs (<1wt%). For certain applications, these loadings are still too high to be commercially viable. In this work we have examined

  3. In search of viable business models for development: sustainable energy in developing countries

    NARCIS (Netherlands)

    Kolk, A.; van den Buuse, D.

    2012-01-01

    Purpose - Although the crucial role of business, and of business-based approaches, in development is increasingly emphasised by academics and practitioners, insight is lacking into the "whether and how" of viable business models, in environmental, social and economical terms. This article analyses

  4. Credit risk assessment model for Jordanian commercial banks: Neural scoring approach

    Directory of Open Access Journals (Sweden)

    Hussain Ali Bekhet

    2014-01-01

    Full Text Available Despite the increase in the number of non-performing loans and competition in the banking market, most of the Jordanian commercial banks are reluctant to use data mining tools to support credit decisions. Artificial neural networks represent a new family of statistical techniques and promising data mining tools that have been used successfully in classification problems in many domains. This paper proposes two credit scoring models using data mining techniques to support loan decisions for the Jordanian commercial banks. Loan application evaluation would improve credit decision effectiveness and control loan office tasks, as well as save analysis time and cost. Both accepted and rejected loan applications, from different Jordanian commercial banks, were used to build the credit scoring models. The results indicate that the logistic regression model performed slightly better than the radial basis function model in terms of the overall accuracy rate. However, the radial basis function was superior in identifying those customers who may default.

  5. Enterocolic lymphocytic phlebitis: statistical analysis of histology features in viable and ischemic bowel.

    Science.gov (United States)

    Medlicott, Shaun A C; Guggisberg, Kelly A; DesCôteaux, Jean-Gaston; Beck, Paul

    2006-07-01

    Enterocolic lymphocytic phlebitis is a rare cause of segmental ischemic enterocolitis. This artery-sparing transmural vasculitis is classically a circumferential phlebitis with perivenular lymphocyte cuffing and thrombi in the absence of systemic manifestations. Myointimal hyperplasia may represent a chronic phase of enterocolic lymphocytic phlebitis. Subclinical or early stage enterocolic lymphocytic phlebitis is not well delineated. We analyzed 600 submucosal and subserosal veins from both ischemic and intact bowel segments to discern if vascular morphology varied between sites. Crescentic and circumferential lymphocytic phlebitis is more common in viable bowel than in the ischemic segment. A nonsignificant trend was found for increased crescentic morphology between intact bowel remote from the ischemic focus compared with that adjacent to the ischemic focus. Hallmarks of ischemic bowel are necrotizing phlebitis and thrombi formation. Thrombophlebitis morphology is distinctly different in viable and ischemic bowel, changing from the classic lymphocytic to necrotizing lesions respectively.

  6. Blood flow, flow reserve, and glucose utilization in viable and nonviable myocardium in patients with ischemic cardiomyopathy.

    Science.gov (United States)

    Zhang, Xiaoli; Schindler, Thomas H; Prior, John O; Sayre, James; Dahlbom, Magnus; Huang, Sung-Cheng; Schelbert, Heinrich R

    2013-04-01

    The aim of the study was to determine whether glucose uptake in viable myocardium of ischemic cardiomyopathy patients depends on rest myocardial blood flow (MBF) and the residual myocardial flow reserve (MFR). Thirty-six patients with ischemic cardiomyopathy (left ventricular ejection fraction 25 ± 10 %) were studied with (13)N-ammonia and (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET). Twenty age-matched normals served as controls. Regional MBF was determined at rest and during dipyridamole hyperemia and regional FDG extraction was estimated from regional FDG to (13)N-ammonia activity ratios. Rest MBF was reduced in viable (0.42 ± 0.18 ml/min per g) and nonviable regions (0.32 ± 0.09 ml/min per g) relative to remote regions (0.68 ± 0.23 ml/min per g, p MFRs did not differ significantly (p > 0.05). Compared to MFR in remote myocardium, MFRs in viable regions were similar (1.39 ± 0.56 vs 1.70 ± 0.45, p > 0.05) but were significantly lower in nonviable regions (1.23 ± 0.43, p MFRs (r =-0.424, p MFRs in viable myocardium are associated with increasing glucose extraction that likely reflects a metabolic adaptation of remodeling hibernating myocytes.

  7. The New Anechoic Shielded Chambers Designed for Space and Commercial Applications at LIT

    Science.gov (United States)

    da Silva, Benjamim; Galvao, M. C.; Pereira, Clovis Solano

    2008-01-01

    The main objective of this paper is to present the capabilities of the new anechoic shielded rooms designed for space and commercial applications as part of the Integration and Testing Laboratory (LIT, Laboratorio de Integracao e Testes) in Brazil. A new anechoic shielded room named CBA2 has been in full operation since March 2007 and a remodeled chamber CBA1 is planned to be ready by the end of 2008, replacing an old facility which was in operation for the last 18 years. The Brazilian Space Program started with very small and simple satellites and the old CBA1 chamber was conceived in 1987 to accomplish the EMI/EMC tests not requiring significant volumes. Since the very beginning this facility was also used by the private sector for other applications mainly due to the absorption of digital electronics in all kind of products. The intense use of this facility during the last years, operating three shifts a day, caused a normal degradation and imposed several limitations. Therefore, a new totally remodeled chamber was designed considering the state of the art in terms of absorbers and associated instrumentation. On the other hand the facility CBA2 was conceived, designed and implemented to test large satellites taking into account the advance of the technology in terms of RF frequencies, power level, testing methodologies and several other factors. A very interesting and unique aspect of this project was the partnership between the private sector and governmental institution. As a result, the total investment was shared between several companies and consequently a time-sharing use of the facility as well.

  8. Finding viable models in SUSY parameter spaces with signal specific discovery potential

    Science.gov (United States)

    Burgess, Thomas; Lindroos, Jan Øye; Lipniacka, Anna; Sandaker, Heidi

    2013-08-01

    Recent results from ATLAS giving a Higgs mass of 125.5 GeV, further constrain already highly constrained supersymmetric models such as pMSSM or CMSSM/mSUGRA. As a consequence, finding potentially discoverable and non-excluded regions of model parameter space is becoming increasingly difficult. Several groups have invested large effort in studying the consequences of Higgs mass bounds, upper limits on rare B-meson decays, and limits on relic dark matter density on constrained models, aiming at predicting superpartner masses, and establishing likelihood of SUSY models compared to that of the Standard Model vis-á-vis experimental data. In this paper a framework for efficient search for discoverable, non-excluded regions of different SUSY spaces giving specific experimental signature of interest is presented. The method employs an improved Markov Chain Monte Carlo (MCMC) scheme exploiting an iteratively updated likelihood function to guide search for viable models. Existing experimental and theoretical bounds as well as the LHC discovery potential are taken into account. This includes recent bounds on relic dark matter density, the Higgs sector and rare B-mesons decays. A clustering algorithm is applied to classify selected models according to expected phenomenology enabling automated choice of experimental benchmarks and regions to be used for optimizing searches. The aim is to provide experimentalist with a viable tool helping to target experimental signatures to search for, once a class of models of interest is established. As an example a search for viable CMSSM models with τ-lepton signatures observable with the 2012 LHC data set is presented. In the search 105209 unique models were probed. From these, ten reference benchmark points covering different ranges of phenomenological observables at the LHC were selected.

  9. Direct analysis in real time-Mass spectrometry (DART-MS) in forensic and security applications.

    Science.gov (United States)

    Pavlovich, Matthew J; Musselman, Brian; Hall, Adam B

    2018-03-01

    Over the last decade, direct analysis in real time (DART) has emerged as a viable method for fast, easy, and reliable "ambient ionization" for forensic analysis. The ability of DART to generate ions from chemicals that might be present at the scene of a criminal activity, whether they are in the gas, liquid, or solid phase, with limited sample preparation has made the technology a useful analytical tool in numerous forensic applications. This review paper summarizes many of those applications, ranging from the analysis of trace evidence to security applications, with a focus on providing the forensic scientist with a resource for developing their own applications. The most common uses for DART in forensics are in studying seized drugs, drugs of abuse and their metabolites, bulk and detonated explosives, toxic chemicals, chemical warfare agents, inks and dyes, and commercial plant and animal products that have been adulterated for economic gain. This review is meant to complement recent reviews that have described the fundamentals of the ionization mechanism and the general use of DART. We describe a wide range of forensic applications beyond the field of analyzing drugs of abuse, which dominates the literature, including common experimental and data analysis methods. © 2016 Wiley Periodicals, Inc. Mass Spec Rev 37:171-187, 2018. © 2016 Wiley Periodicals, Inc.

  10. 77 FR 30919 - Commercial Driver's License Testing and Commercial Learner's Permit Standards

    Science.gov (United States)

    2012-05-24

    ..., and 385 [Docket No. FMCSA-2007-27659] Commercial Driver's License Testing and Commercial Learner's... published a final rule titled ``Commercial Driver's License Testing and Commercial Learner's Permit... additional drivers, primarily those transporting certain tanks temporarily attached to the commercial motor...

  11. Commercial cyclotrons. Part I: Commercial cyclotrons in the energy range 10 30 MeV for isotope production

    Science.gov (United States)

    Papash, A. I.; Alenitsky, Yu. G.

    2008-07-01

    A survey of commercial cyclotrons for production of medical and industrial isotopes is presented. Compact isochronous cyclotrons which accelerate negative hydrogen ions in the energy range 10 30 MeV have been widely used over the last 25 years for production of medical isotopes and other applications. Different cyclotron models for the energy range 10 12 MeV with moderate beam intensity are used for production of 11C, 13N, 15O, and 18F isotopes widely applied in positron emission tomography. Commercial cyclotrons with high beam intensity are available on the market for production of most medical and industrial isotopes. In this work, the physical and technical parameters of different models are compared. Possibilities of improving performance and increasing intensity of H- beams up to 2 3 mA are discussed.

  12. Real-time monitoring of non-viable airborne particles correlates with airborne colonies and represents an acceptable surrogate for daily assessment of cell-processing cleanroom performance.

    Science.gov (United States)

    Raval, Jay S; Koch, Eileen; Donnenberg, Albert D

    2012-10-01

    Airborne particulate monitoring is mandated as a component of good manufacturing practice. We present a procedure developed to monitor and interpret airborne particulates in an International Organization for Standardization (ISO) class 7 cleanroom used for the cell processing of Section 351 and Section 361 products. We collected paired viable and non-viable airborne particle data over a period of 1 year in locations chosen to provide a range of air quality. We used receiver operator characteristic (ROC) analysis to determine empirically the relationship between non-viable and viable airborne particle counts. Viable and non-viable particles were well-correlated (r(2) = 0.78), with outlier observations at the low end of the scale (non-viable particles without detectable airborne colonies). ROC analysis predicted viable counts ≥ 0.5/feet(3) (a limit set by the United States Pharmacopeia) at an action limit of ≥ 32 000 particles (≥ 0.5 µ)/feet(3), with 95.6% sensitivity and 50% specificity. This limit was exceeded 2.6 times during 18 months of retrospective daily cleanroom data (an expected false alarm rate of 1.3 times/year). After implementing this action limit, we were alerted in real time to an air-handling failure undetected by our hospital facilities management. A rational action limit for non-viable particles was determined based on the correlation with airborne colonies. Reaching or exceeding the action limit of 32 000 non-viable particles/feet(3) triggers suspension of cleanroom cell-processing activities, deep cleaning, investigation of air handling, and a deviation management process. Our full procedure for particle monitoring is available as an online supplement.

  13. The ghost of extinction: Preservation values and minimum viable population in wildlife models

    NARCIS (Netherlands)

    Eiswerth, M.E.; Kooten, van G.C.

    2009-01-01

    The inclusion of a minimum viable population in bioeconomic modeling creates at least two complications that are not resolved by using a modified logistic growth function. The first complication can be dealt with by choosing a different depensational growth function. The second complication relates

  14. 10 MMBt/Hr AFBC Commercial Demonstration Cedar Lane Farms

    Energy Technology Data Exchange (ETDEWEB)

    Harold M. Keener; Mary H. Wicks; Tom Machamer; Dave Hoecke; Don Bonk; Bob Brown

    2005-10-31

    The objective of this project was to demonstrate and promote the commercialization of coal-fired atmospheric fluidized bed combustion (AFBC) systems, with limestone addition for SO2 emissions control and a baghouse for particulate emissions control. This AFBC system was targeted for small scale industrial-commercial-institutional space and process heat applications in the 4-40 MMBtu/hr size range. A cost effective and environmentally acceptable AFBC technology in this size range could displace a considerable amount of heating gas and oil with coal, while resulting in significant total cost savings to the owner/operators.

  15. Viable Bacteria Associated with Red Blood Cells and Plasma in Freshly Drawn Blood Donations

    DEFF Research Database (Denmark)

    Damgaard, Christian; Magnussen, Karin; Enevold, Christian

    2015-01-01

    ) or blue lactose plates. For identification colony PCR was performed using primers targeting 16S rDNA. SETTING: Blood donors attending Capital Region Blood Bank, Copenhagen University Hospital, Rigshospitalet, Hvidovre, Denmark, October 29th to December 10th 2013. PARTICIPANTS: 60 donors (≥50 years old....... CONCLUSIONS: Viable bacteria are present in blood from donors self-reported as medically healthy, indicating that conventional test systems employed by blood banks insufficiently detect bacteria in plasma. Further investigation is needed to determine whether routine testing for anaerobic bacteria and testing......OBJECTIVES: Infection remains a leading cause of post-transfusion mortality and morbidity. Bacterial contamination is, however, detected in less than 0.1% of blood units tested. The aim of the study was to identify viable bacteria in standard blood-pack units, with particular focus on bacteria from...

  16. Defined Combinations of Cryomedia and Thawing Extenders Influence the Viable X-Y Boar Sperm Ratio in Vitro.

    Science.gov (United States)

    Korchunjit, W; Kaeoket, K; Kitiyanant, Y; Taylor, J; Wongtawan, T

    It is believed that plasma membrane X- and Y-chromosome bearing sperm are different; therefore the freezing and thawing process may affect X- and Y-sperm differently. The objective of this study was to investigate the effect of cryomedia and thawing extenders on the survival of X and Y-sperm. Three different cryomedia and thawing extenders were compared. Viable motile sperm were separated using a swim-up technique. Real-time PCR was used to identify the sperm type. Using CryoA for freezing and Beltsville-Thawing-Solution (BTS) as the thawing extender yielded significantly higher numbers of viable motile Y sperm (64 percent) than control (48 percent) (P semen freezing with CryoC and thawing with Androstar Plus gave a significantly lower number of viable motile Y sperm (32 percent) than control (51 percent). Our results revealed that defined combinations of cryomedia and thawing extenders significantly altered the survival ratio of frozen-thawed X-Y sperm in vitro, which has potential implications for artificial insemination.

  17. Robust Clamping Force Control of an Electro-Mechanical Brake System for Application to Commercial City Buses

    Directory of Open Access Journals (Sweden)

    Sangjune Eum

    2017-02-01

    Full Text Available This paper proposes a sensor-less robust force control method for improving the control performance of an electro-mechanical brake (EMB which is applicable to commercial city buses. The EMB generates the accurate clamping force commanded by a driver through an independent motor control at each wheel instead of using existing mechanical components. In general, an EMB undergoes parameter variation and a backdrivability problem. For this reason, the cascade control strategy (e.g., force-position cascade control structure is proposed and the disturbance observer is employed to enhance control robustness against model variations. Additionally, this paper proposed the clamping force estimation method for a sensor-less control, i.e., the clamping force observer (CFO. Finally, in order to confirm the performance and effectiveness of a proposed robust control method, several experiments are performed and analyzed.

  18. Technical and economic assessments commercial success for IGCC technology in China

    International Nuclear Information System (INIS)

    Xiong, T.

    1998-01-01

    The experiences gained from several Integrated Gasification Combined Cycle (IGCC) demonstration plants operating in the US and Europe facilitate commercial success of this advanced coal-based power generation technology. However, commercialization of coal-based IGCC technology in the West, particularly in the US, is restricted due to the low price of natural gas. On the contrary, in China--the largest coal producer and consumer in the world--a lack of natural gas supply, strong demand for air pollution control and relatively low costs of manufacturing and construction provide tremendous opportunities for IGCC applications. The first Chinese IGCC demonstration project was initiated in 1994, and other potential IGCC projects are in planning. IGCC applications in re-powering, fuel switching and multi-generation also show a great market potential in China. However, questions for IGCC development in China remain; where are realistic opportunities for IGCC projects and how can these opportunities be converted into commercial success? The answers to these questions should focus on the Chinese market needs and emphasize economic benefits, not just clean, or power. High price of imported equipment, high financing costs, and the technical risk of first-of-a-kind installation barricade IGCC development in China. This paper presents preliminary technical and economic assessments for four typical IGCC applications in the Chinese marketplace: central power station, fuel switching, re-powering, and multi-generation. The major factors affecting project economics--such as plant cost, financing, prices of fuel and electricity and operating capacity factor--are analyzed. The results indicate that well-proven technology for versatile applications, preferred financing, reduction of the plant cost, environmental superiority and appropriate project structure are the key for commercial success of IGCC in China

  19. Automatic dosimeter for kerma measurement based on commercial PIN photo diodes

    International Nuclear Information System (INIS)

    Kushpil, V.; Kushpil, S.; Huna, Z.

    2011-01-01

    A new automatic dosimeter for measurement of radiation dose from neutron and ionization radiation is presented. The dosimeter (kerma meter) uses commercial PIN diodes with long base as its active element. Later it provides a maximal dependence of the minority carriers life time versus absorbed dose. The characteristics of the dosimeter were measured for several types of commercial diodes. Device can be useful in many environmental or industrial applications. (authors)

  20. Estimating the energy-saving benefit of reduced-flow and/or multi-speed commercial kitchen ventilation systems

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.; Schmid, F.; Spata, A.J.

    1999-07-01

    Kitchen exhaust ventilation systems are recognized as a major energy user within commercial food service facilities and restaurants. Minimizing the design ventilation rate of an appliance/hood system by optimizing hood performance in the laboratory is a viable strategy for reducing the makeup air heating and cooling loads as well as the exhaust and supply fan energy. Cutting back the exhaust flow under conditions of noncooking (appliance idle) can further reduce the energy load associated with a kitchen ventilation system. An optimized, two-speed exhaust system was installed within the scope of an energy-efficient, quick service restaurant (QSR) design and demonstration project. This paper evaluates the energy benefit of this variable-flow strategy as well as the savings associated with reducing the design ventilation rate (compared to an off-the-shelf exhaust hood). The paper describes a new public-domain software tool for estimating heating and cooling loads associated with the makeup air requirements of commercial kitchens. This bin-based software provides ASHRAE engineers with an alternative to hand calculations or more sophisticated hour-by-hour simulation. The dramatic impact that both makeup air set point and geographic location have on the outdoor air load is illustrated. The paper concludes with an industry-wide projection of energy savings associated with optimizing the design and operation of commercial kitchen ventilation (CKV) systems.

  1. Establishment of a Viable Population of Red-Cockaded Woodpeckers at the Savannah River Site

    International Nuclear Information System (INIS)

    Johnston, P.A.

    2002-01-01

    Report on program's objective to restore viable population of Red-cockaded woodpecker at SRS. Several management strategies were used to promote population expansion of Red-cockaded woodpecker and reduction of interspecific competition with Red-Cockaded woodpecker

  2. Application of commercial sensor manufacturing methods for NOx/NH3 mixed potential sensors for emissions control

    Energy Technology Data Exchange (ETDEWEB)

    Brosha, Eric L [Los Alamos National Laboratory; Mukundan, Rangachary [Los Alamos National Laboratory; Nelson, Mark A [Los Alamos National Laboratory; Sekhar, Praveen [Los Alamos National Laboratory; Williamson, Todd [Los Alamos National Laboratory; Garzon, Fernando H [Los Alamos National Laboratory

    2009-01-01

    The purpose of this research effort is to develop a low cost on-board Nitrogen Oxide (NO{sub x})/Ammonia (NH{sub 3}) sensor that can not only be used for emissions control but has the potential to improve efficiency through better monitoring of the combustion process and feedback control in both vehicle and stationary systems. Over the past decade, Los AJamos National Laboratory (LANL) has developed a unique class of electrochemical gas sensors for the detection of carbon monoxide, hydrocarbons, hydrogen and nitrogen oxides. These sensors are based on the mixed-potential phenomenon and are a modification of the existing automotive lambda (oxygen) sensor and have the potential to meet the stringent sensitivity, selectivity and stability requirements of an on-board emissions/engine control sensor system. The current state of the art LANL technology is based on the stabilization of the electrochemical interfaces and relies on an externally heated, hand-made, tape cast device. We are now poised to apply our patented sensing principles in a mass production sensor platform that is more suitable for real world engine-out testing such as on dynamometers for vehicle applications and for exhaust-out testing in heavy boilers/SCR systems in power plants. In this present work, our goal is to advance towards commercialization of this technology by packaging the unique LANL sensor design in a standard automotive sensor-type platform. This work is being performed with the help of a leading US technical ceramics firm, utilizing commercial manufacturing techniques. Initial tape cast platforms with screen printed metal oxide and Pt sensor electrodes have shown promising results but also clearly show the need for us to optimize the electrode and electrolyte compositions/morphologies and interfaces of these devices in order to demonstrate a sensitive, selective, and stable NO{sub x} sensor. Our previous methods and routes to preparing stable and reproducible mixed potential sensors

  3. Value of Information Web Application

    Science.gov (United States)

    2015-04-01

    their understanding of VoI attributes (source reliable, information content, and latency). The VoI web application emulates many features of a...only when using the Firefox web browser on those computers (Internet Explorer was not viable due to unchangeable user settings). During testing, the

  4. Thermal spray for commercial shipbuilding

    Science.gov (United States)

    Rogers, F. S.

    1997-09-01

    Thermal spraying of steel with aluminum to protect it from corrosion is a technology that has been proven to work in the marine environment. The thermal spray coating system includes a paint sealer that is applied over the thermally sprayed aluminum. This extends the service life of the coating and provides color to the end product. The thermal spray system protects steel both through the principle of isolation (as in painting) and galvanizing. With this dual protection mechanism, steel is protected from corrosion even when the coating is damaged. The thermal- sprayed aluminum coating system has proved the most cost- effective corrosion protection system for the marine environment. Until recently, however, the initial cost of application has limited its use for general application. Arc spray technology has reduced the application cost of thermal spraying of aluminum to below that of painting. Commercial shipbuilders could use this technology to enhance their market position in the marine industry.

  5. Current Perspectives on Viable but Non-culturable State in Foodborne Pathogens

    OpenAIRE

    Zhao, Xihong; Zhong, Junliang; Wei, Caijiao; Lin, Chii-Wann; Ding, Tian

    2017-01-01

    The viable but non-culturable (VBNC) state, a unique state in which a number of bacteria respond to adverse circumstances, was first discovered in 1982. Unfortunately, it has been reported that many foodborne pathogens can be induced to enter the VBNC state by the limiting environmental conditions during food processing and preservation, such as extreme temperatures, drying, irradiation, pulsed electric field, and high pressure stress, as well as the addition of preservatives and disinfectant...

  6. IMS applications analysis

    Energy Technology Data Exchange (ETDEWEB)

    RODACY,PHILIP J.; REBER,STEPHEN D.; SIMONSON,ROBERT J.; HANCE,BRADLEY G.

    2000-03-01

    This report examines the market potential of a miniature, hand-held Ion Mobility Spectrometer. Military and civilian markets are discussed, as well as applications in a variety of diverse fields. The strengths and weaknesses of competing technologies are discussed. An extensive Ion Mobility Spectrometry (IMS) bibliography is included. The conclusions drawn from this study are: (1) There are a number of competing technologies that are capable of detecting explosives, drugs, biological, or chemical agents. The IMS system currently represents the best available compromise regarding sensitivity, specificity, and portability. (2) The military market is not as large as the commercial market, but the military services are more likely to invest R and D funds in the system. (3) Military applications should be addressed before commercial applications are addressed. (4) There is potentially a large commercial market for rugged, hand-held Ion Mobility Spectrometer systems. Commercial users typically do not invest R and D funds in this type of equipment rather, they wait for off-the-shelf availability.

  7. Organophilization and characterization of commercial bentonite clays

    International Nuclear Information System (INIS)

    Cunha, B.B. da; Lima, J.C.C.; Alves, A.M.; Araujo, E.M.; Melo, T.J.A. de

    2012-01-01

    Bentonite clay is a plastic changes resulting from volcanic ash, consisting mostly of montmorillonite. The state of Paraiba is a major source of bentonite clay from Brazil, where the main oil fields are located in Boa Vista and represents the largest national production of raw and beneficiated bentonite. Aimed at the commercial value of this type of clay and its high applicability in the polls, this article aims to make a comparison between two kinds of clay, a national (Brasgel) and other imported (Cloisite) from organophilization of two commercial bentonite, ionic surfactant with Praepagem WB, and characterize them by XRD, FTIR and TG / DTG. We observe that despite getting inferior properties, the clay presents national values very similar to those presented by imported clay. (author)

  8. Commercial-vehicle enforcement: a guide for law-enforcement managers

    International Nuclear Information System (INIS)

    1987-01-01

    The purpose of the document is to provide a resource for law enforcement agencies to evaluate their programs, and to promote the uniform application of concepts already shown to be effective in other jurisdictions, which identify and address commercial-vehicle traffic safety needs

  9. Market Assessment and Demonstration of Lignite FBC Ash Flowable Fill Applications

    International Nuclear Information System (INIS)

    Alan E. Bland

    2003-01-01

    Montana-Dakota Utilities (MDU) and Western Research Institute (WRI) have been developing flowable fill materials formulated using ash from the Montana-Dakota Utilities R. M. Heskett Station in Mandan, North Dakota. MDU and WRI have partnered with the U.S. Department of Energy (DOE) and the North Dakota Industrial Commission (NDIC) to further the development of these materials for lignite-fired fluidized-bed combustion (FBC) facilities. The MDU controlled density fill (CDF) appears to be a viable engineering material and environmentally safe. WRI is pursuing the commercialization of the technology under the trademark Ready-Fill(trademark). The project objectives were to: (1) assess the market in the Bismarck-Mandan area; (2) evaluate the geotechnical properties and environmental compatibility; and (3) construct and monitor demonstrations of the various grades of flowable fill products in full-scale demonstrations. The scope of initial phase of work entailed the following: Task I--Assess Market for MDU Flowable Fill Products; Task II--Assess Geotechnical and Environmental Properties of MDU Flowable Fill Products; and Task III--Demonstrate and Monitor MDU Flowable Fill Products in Field-Scale Demonstrations. The results of these testing and demonstration activities proved the following: (1) The market assessment indicated that a market exists in the Bismarck-Mandan area for structural construction applications, such as sub-bases for residential and commercial businesses, and excavatable fill applications, such as gas line and utility trench filling. (2) The cost of the MDU flowable fill product must be lower than the current $35-$45/cubic yard price if it is to become a common construction material. Formulations using MDU ash and lower-cost sand alternatives offer that opportunity. An estimated market of 10,000 cubic yards of MDU flowable fill products could be realized if prices could be made competitive. (3) The geotechnical properties of the MDU ash-based flowable

  10. Market Assessment and Demonstration of Lignite FBC Ash Flowable Fill Applications

    Energy Technology Data Exchange (ETDEWEB)

    Alan E. Bland

    2003-09-30

    Montana-Dakota Utilities (MDU) and Western Research Institute (WRI) have been developing flowable fill materials formulated using ash from the Montana-Dakota Utilities R. M. Heskett Station in Mandan, North Dakota. MDU and WRI have partnered with the U.S. Department of Energy (DOE) and the North Dakota Industrial Commission (NDIC) to further the development of these materials for lignite-fired fluidized-bed combustion (FBC) facilities. The MDU controlled density fill (CDF) appears to be a viable engineering material and environmentally safe. WRI is pursuing the commercialization of the technology under the trademark Ready-Fill{trademark}. The project objectives were to: (1) assess the market in the Bismarck-Mandan area; (2) evaluate the geotechnical properties and environmental compatibility; and (3) construct and monitor demonstrations of the various grades of flowable fill products in full-scale demonstrations. The scope of initial phase of work entailed the following: Task I--Assess Market for MDU Flowable Fill Products; Task II--Assess Geotechnical and Environmental Properties of MDU Flowable Fill Products; and Task III--Demonstrate and Monitor MDU Flowable Fill Products in Field-Scale Demonstrations. The results of these testing and demonstration activities proved the following: (1) The market assessment indicated that a market exists in the Bismarck-Mandan area for structural construction applications, such as sub-bases for residential and commercial businesses, and excavatable fill applications, such as gas line and utility trench filling. (2) The cost of the MDU flowable fill product must be lower than the current $35-$45/cubic yard price if it is to become a common construction material. Formulations using MDU ash and lower-cost sand alternatives offer that opportunity. An estimated market of 10,000 cubic yards of MDU flowable fill products could be realized if prices could be made competitive. (3) The geotechnical properties of the MDU ash-based flowable

  11. Immediate natural tooth pontic: A viable yet temporary prosthetic solution: A patient reported outcome

    Directory of Open Access Journals (Sweden)

    Sudhir Bhandari

    2012-01-01

    Conclusion: The concept of immediate pontic placement is surely a viable treatment option and promises an excellent transient esthetic solution for a lost tooth as well as enables good preparation of the extraction site for future prosthetic replacement.

  12. Exploring the potential of commercial polyethylene membranes for desalination by membrane distillation

    KAUST Repository

    Zuo, Jian; Bonyadi, Sina; Chung, Neal Tai-Shung

    2015-01-01

    The potential of utilizing polyethylene (PE) membranes in membrane distillation (MD) for sea water desalination has been explored in this study. The advantages of using PE membranes are (1) their intrinsic hydrophobicity with low surface energy of 28-33×10N/m, (2) good chemical stability and low thermal conductivity and (3) their commercial availability that may expedite the MD commercialization process. Several commercial PE membranes with different physicochemical properties are employed to study the capability and feasibility of PE membrane application in an MD process. The effect of membrane pore size, porosity, thickness and wetting resistance on MD performance and energy efficiency have been investigated. The PE membranes demonstrate impressive separation performance with permeation fluxes reaching 123.0L/mh for a 3.5wt% sodium chloride (NaCl) feed solution at 80°C. This superior performance surpasses most of the prior commercial and lab-made flat sheet and hollow fiber membranes. A long term MD testing of 100h is also performed to evaluate the durability of PE membranes, and a relatively stable performance is observed during the entire experiment. This long term stability signifies the suitability of PE membranes for MD applications.

  13. Exploring the potential of commercial polyethylene membranes for desalination by membrane distillation

    KAUST Repository

    Zuo, Jian

    2015-09-26

    The potential of utilizing polyethylene (PE) membranes in membrane distillation (MD) for sea water desalination has been explored in this study. The advantages of using PE membranes are (1) their intrinsic hydrophobicity with low surface energy of 28-33×10N/m, (2) good chemical stability and low thermal conductivity and (3) their commercial availability that may expedite the MD commercialization process. Several commercial PE membranes with different physicochemical properties are employed to study the capability and feasibility of PE membrane application in an MD process. The effect of membrane pore size, porosity, thickness and wetting resistance on MD performance and energy efficiency have been investigated. The PE membranes demonstrate impressive separation performance with permeation fluxes reaching 123.0L/mh for a 3.5wt% sodium chloride (NaCl) feed solution at 80°C. This superior performance surpasses most of the prior commercial and lab-made flat sheet and hollow fiber membranes. A long term MD testing of 100h is also performed to evaluate the durability of PE membranes, and a relatively stable performance is observed during the entire experiment. This long term stability signifies the suitability of PE membranes for MD applications.

  14. Experimental performance evaluation for a carbon dioxide light commercial cooling application under transcritical and subcritical conditions

    International Nuclear Information System (INIS)

    Boccardi, G.; Calabrese, N.; Celata, G.P.; Mastrullo, R.; Mauro, A.W.; Perrone, A.; Trinchieri, R.

    2013-01-01

    CO 2 is one of the most interesting non toxic, nor flammable, low GWP natural fluid to be used in applications with a large direct contribution to global warming, such as vending machines. In this paper the results of an experimental investigation on a small capacity, air-forced refrigerating plant working with CO 2 are presented. The air inlet temperatures at gas cooler and evaporator were varied between 16 °C and 31 °C and between −25 °C and 25 °C, respectively, to cover the range of temperatures under conditions typical of commercial refrigeration, during quasi-steady operation. The thermodynamic analysis of the system performance was carried on varying independently the pressure at the gas cooler, by overfeeding the liquid receiver to point out the effect of refrigerant charge. The results allow to describe the performance of the system in a map varying the boundary conditions; at the same time the corresponding variations of the thermodynamic cycle, the COP and the mass flow rate are reported. -- Highlights: ► A light commercial refrigerating plant working with CO 2 was tested in order to evaluate its performance. ► 71 experimental points were collected varying the flow rates, the temperatures of air sources and the refrigerant charge. ► Mass flow rate, cooling capacity, electrical power and COP were evaluated as a function of pressures and superheating. ► The segregate influence of each operating parameter on each performance indicator was calculated. ► A map of plant performance as a function of air source temperatures is reported

  15. Biogas upgrading - Review of commercial technologies; Biogasuppgradering - Granskning av kommersiella tekniker

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Fredric; Hulteberg, Christian; Persson, Tobias; Tamm, Daniel

    2013-04-01

    Biogas production is growing and there is an increasing demand for upgraded biogas, to be used as vehicle fuel or injected to the natural gas grid. To enable the efficient use of biogas in these applications the gas must be upgraded, i.e. the carbon dioxide, which constitutes a large part of the raw biogas from the digester, must be separated from the methane. This report aims to evaluate the biogas upgrading technologies that are commercially available and in operation today: amine scrubbers, water scrubbers, PSA units, organic scrubbers and membrane units. The technologies are described in detail by presenting the theory behind the separation mechanism, the upgrading process as a complete system, operational issues and how these are solved, and finally the most important financial data. Furthermore, the best developed cryogenic technologies, which today are being used to purify landfill gas and biogas from some specific components and to liquefy biogas, are presented. Cryogenic upgrading is an interesting possibility, but as this report shows, the technology still has some important operational issues to resolve. Technologies which are especially focused on small-scale applications are finally presented, however not in as much detail as the other, more common technologies. The report shows that for mid-scale applications, the most common options are all viable. The scrubbing technologies all perform well and have similar costs of investment and operation. The simplicity and reliability of the water scrubber has made this the preferred choice in many applications, but the high purity and very low methane slip from amine scrubbers are important characteristics. Regarding PSA and membrane units, the investment cost for these are about the same as for scrubbers. Furthermore, recent developments of the membrane units have also made it possible to reach low methane slips with this technology. Biogas production is increasing, in Sweden and globally, and the interest for

  16. Radiation Characterization of Commercial GaN Devices

    Science.gov (United States)

    Harris, Richard D.; Scheick, Leif Z.; Hoffman, James P.; Thrivikraman, Tushar; Jenabi, Masud; Gim, Yonggyu; Miyahira, Tetsuo

    2011-01-01

    Radiative feedback from primordial protostars and final mass of the first star Commercially available devices fabricated from GaN are beginning to appear from a number of different suppliers. Based on previous materials and prototype device studies, it is expected that these commercial devices will be quite tolerant to the types of radiation encountered in space. This expectation needs to be verified and the study described herein was undertaken for that purpose. All of the parts discussed in this report are readily available commercially. The parts chosen for study are all targeted for RF applications. Three different studies were performed: 1) a preliminary DDD/TID test of a variety of part types was performed by irradiating with 50 MeV protons, 2) a detailed DDD/TID study of one particular part type was performed by irradiating with 50 MeV protons, and 3) a SEB/SEGR test was performed on a variety of part types by irradiating with heavy ions. No significant degradation was observed in the tests performed in this study.

  17. Profile of Clean Technology Commercialization in the U.S.

    Science.gov (United States)

    Mehta, Manish

    2010-04-01

    In 2009, the National Center for Manufacturing Sciences (NCMS) performed it third successive study of the growth and transition of nanotechnology into commercial products, under award from the National Science Foundation (NSF). Nanotechnology is a recently recognized cross-disciplinary field of a variety of potentially disruptive technologies that involves the creation and operation of objects at the nanoscale, up to 100 nanometers in size. Nanomanufacturing is the large-scale manipulation of matter at the nanoscale, to produce value-added components. Because of the economically significant new markets and breadth of applications that can benefit from the exploitation of these size-driven aspects, much international research and commercial effort is being expended to create revolutionary value-added products using the many capabilities and tools enabled by nanotechnology. In the context of Michigan and many other US states, startup and commercialization activity is especially important in market diversification and job growth initiatives. This trend has accelerated new applications of nanotechnology in industrial and consumer markets related to energy efficiency and environmentally conscious manufacturing, known as ``cleantech." Dr. Mehta’s presentation will illustrate the industry’s major trends, concerns and barriers across key strategic indicators, as well as highlight the characteristics of startup businesses and established players in this important field.

  18. Commercial Research and Development: Power to Explore, Opportunities from Discovery

    Science.gov (United States)

    Casas, Joseph C.; Nall, Mark; Powers, C. Blake; Henderson, Robin N. (Technical Monitor)

    2002-01-01

    The technical and economic goals of commercial use of space are laudable, and are addressed as a high priority by almost every national space program and most major aerospace companies the world over. Yet, the focus of most organizational agendas and discussions tends to focus on one or two very narrow enabling aspects of this potentially large technological and economic opportunity. While government sponsored commercial launch activities and private space platforms are an integral part of efforts to leverage the commercial use of space, these activities are possibly one of the smallest parts of creating, a viable and sustainable market for the commercial use of space. Most of the current programs usually do not appropriately address some of the critical issues of the current, already interested, potential space user communities. Current programs place the focus of the majority of the user requirements on the vehicle payload weight and mass performance considerations as the primary payload economical factor in providing a commercial market with a stimulating price for gaining access to the space environment. The larger user challenges of transformation from Earth-based research and development approaches to space environment approaches are not addressed early enough in programs to impact the new business considerations of potential users. Currently, space-based research and development user activities require a large user investment in time, in development of new areas of support expertise, in development of new systems, in risk of schedule to completion, and in long term capital positioning. The larger opportunities for stimulating a strong market driven interest in commercial use of space that could result from the development of vehicle payload "leap ahead technologies" for users are being missed, and there is a real risk of limiting the potentially broader market base to support a more technologically advanced and economically lucrative outcome. A major driving

  19. Development of active, nanoparticle, antimicrobial technologies for muscle-based packaging applications.

    Science.gov (United States)

    Morris, Michael A; Padmanabhan, Sibu C; Cruz-Romero, Malco C; Cummins, Enda; Kerry, Joseph P

    2017-10-01

    Fresh and processed muscle-based foods are highly perishable food products and packaging plays a crucial role in providing containment so that the full effect of preservation can be achieved through the provision of shelf-life extension. Conventional packaging materials and systems have served the industry well, however, greater demands are being placed upon industrial packaging formats owing to the movement of muscle-based products to increasingly distant markets, as well as increased customer demands for longer product shelf-life and storage capability. Consequently, conventional packaging materials and systems will have to evolve to meet these challenges. This review presents some of the new strategies that have been developed by employing novel nanotechnological concepts which have demonstrated some promise in significantly extending the shelf-life of muscle-based foods by providing commercially-applicable, antimicrobially-active, smart packaging solutions. The primary focus of this paper is applied to subject aspects, such as; material chemistries employed, forming methods utilised, interactions of the packaging functionalities including nanomaterials employed with polymer substrates and how such materials ultimately affect microbes. In order that such materials become industrially feasible, it is important that safe, stable and commercially-viable packaging materials are shown to be producible and effective in order to gain public acceptance, legislative approval and industrial adoption. Copyright © 2017. Published by Elsevier Ltd.

  20. Technical-financial evaluation of rainwater harvesting systems in commercial buildings-case ase studies from Sonae Sierra in Portugal and Brazil.

    Science.gov (United States)

    Sousa, Vitor; Silva, Cristina Matos; Meireles, Inês C

    2017-11-10

    Water is an essential and increasingly scarce resource that should be preserved. The evolution of the human population and communities has contributed to the global decrease of potable water availability and the reduction of its consumption is now compulsory. Rainwater harvesting systems (RWHS) are emerging as a viable alternative source for water consumption in non-potable uses. The present study aims to contribute to the promotion of water efficiency, focusing on the application of rainwater harvesting systems in commercial buildings, and comprises four stages: (i) development of a technical evaluation tool to aid the design of RWHS and support their financial evaluation; (ii) validation of the tool using operational data from an existing RWHS installed at Colombo Shopping Center, in Lisbon, Portugal; (iii) assessment of the sensibility of the technical evaluation tool results to the variation of the inputs, namely the precipitation and consumption, through a parametric analysis for the Colombo Shopping Center; and (iv) comparison of the performance and financial feasibility of hypothetical RWHS in two existing commercial buildings. The technical tool was applied to two Sonae Sierra's shopping centers, one in Portugal and one in Brazil. The installation of a 200-m 3 tank is advised for the first case study, allowing non-potable water savings of 60% but a payback period of about 19 years. In the Brazilian shopping, the implementation of a tank with a capacity ranging from 100 to 400 m 3 leads to non-potable savings between 20 and 50%, but with smaller payback period, under 2 years, due to the relatively lower investment costs and higher water fees.

  1. Commercial Buildings Characteristics, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-29

    Commercial Buildings Characteristics 1992 presents statistics about the number, type, and size of commercial buildings in the United States as well as their energy-related characteristics. These data are collected in the Commercial Buildings Energy Consumption Survey (CBECS), a national survey of buildings in the commercial sector. The 1992 CBECS is the fifth in a series conducted since 1979 by the Energy Information Administration. Approximately 6,600 commercial buildings were surveyed, representing the characteristics and energy consumption of 4.8 million commercial buildings and 67.9 billion square feet of commercial floorspace nationwide. Overall, the amount of commercial floorspace in the United States increased an average of 2.4 percent annually between 1989 and 1992, while the number of commercial buildings increased an average of 2.0 percent annually.

  2. Application of reactors for testing neutron-induced upsets in commercial SRAMs

    International Nuclear Information System (INIS)

    Griffin, P.J.; Luera, T.F.; Sexton, F.W.; Cooper, P.J.; Karr, S.G.; Hash, G.L.; Fuller, E.

    1997-01-01

    Reactor neutron environments can be used to test/screen the sensitivity of unhardened commercial SRAMs to low-LET neutron-induced upset. Tests indicate both thermal/epithermal (< 1 keV) and fast neutrons can cause upsets in unhardened parts. Measured upset rates in reactor environments can be used to model the upset rate for arbitrary neutron spectra

  3. Techno-commercial aspects of food irradiation in India

    International Nuclear Information System (INIS)

    Sharma, Arun; Madhusoodanan, P.

    2012-01-01

    Research and development work has been carried out at Food Technology Division of Bhabha Atomic Research Center for more than past fifty years. After establishing potential commercial applications, a lot of time and efforts were spent on proving the wholesomeness and nutritional adequacy of irradiated foods. The first approval from health authorities came in 1994 for processing potato, onion and spices. Additional commodities were approved in 1998 and 2001, bringing the list of commodities to more than 20. Two technology demonstration plants were set up by the government, one for high dose applications like microbial decontamination of spices and dry vegetables in 2000, and another for low dose applications, like sprout inhibition and insect disinfestation, in 2003. In 2004, irradiation was approved as a quarantine measure. This enabled export of mango to USA after a gap of 18 years in 2007. More than a dozen plants have now been set up by private entrepreneurs in the country. - Highlights: ► The paper reports historical developments and current status of food irradiation in India. ► Some R and D and techno-commercial aspects are highlighted. ► The paper is based on an invited talk delivered during IMRP-2011 in Food Irradiation-Phytosan II Session.

  4. Application of quality risk management to set viable environmental monitoring frequencies in biotechnology processing and support areas.

    Science.gov (United States)

    Sandle, Tim

    2012-01-01

    Environmental monitoring programs are essential for pharmaceutical facilities in order to assess the level of environmental control. For biotechnology facilities there is little advice as to the frequency at which viable environmental monitoring should be conducted. This paper outlines an approach, based on the principles of quality risk management, for the development of a framework from which monitoring frequencies can be determined. This involved the identification of common hazards and the evaluation those hazards in terms of the severity of contamination and the probability of contamination occurring. These elements of risk were evaluated for different cleanrooms and the relative risks ranked. Once the risk scores were calculated, the methods for detecting risks within the cleanrooms were assessed. Risk filtering was then used to group different cleanrooms based on their relative risks and detection methods against predetermined monitoring frequencies. Through use of case study examples, the paper presents the model and describes how appropriate frequencies for the environmental monitoring of cleanrooms can be set. Cleanrooms in which biotechnology pharmaceutical processing takes place are subject to environmental monitoring. The frequency at which such monitoring should be performed can be difficult to determine. This paper uses quality risk assessment methods to construct a framework for determining monitoring frequencies and illustrates the suitability of the framework through a case study.

  5. Use of Commercial I and C in the Next Generation of Nuclear Power

    International Nuclear Information System (INIS)

    Johnson, G. L.

    2006-01-01

    The powerpoint presentation highlighted the following points: we should position ourselves to take better advantage of commercial equipment; the industry is taking certification for safety application seriously; we need ways to take advantage of these certifications rather than starting from zero; there will be gaps; and bridging these gaps will bring commercial technology to our market more quickly

  6. 16 CFR 1034.102 - Application.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Application. 1034.102 Section 1034.102 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS... Application. This part applies to all programs or activities conducted by the agency. ...

  7. Commercial products and services of research reactors. Proceedings of a technical meeting held in Vienna 28 June - 2 July 2010

    International Nuclear Information System (INIS)

    2013-07-01

    the utilization of research reactors and their sustainability through financially viable services and international cooperation. In this report, reference is also made to a similar IAEA technical meeting on 'Commercial Applications of Nuclear Analytical Techniques', held in Vienna, Austria, from 23 to 26 November 2004, and a few recently updated papers from that meeting have been included here. This publication summarizes the individual reports presented during the above meetings, and details the overall findings and conclusions jointly identified and agreed upon by the meeting participants. The individual papers are available on the CD-ROM attached to this publication

  8. Energy analysis of fuel cell system for commercial greenhouse application – A feasibility study

    International Nuclear Information System (INIS)

    Vadiee, Amir; Yaghoubi, Mahmoud; Sardella, Marco; Farjam, Pardis

    2015-01-01

    Highlights: • Feasibility study of integrating a PEMFC with a commercial greenhouse. • An energy analysis has been performed in order to evaluate the energetic performance of the system. • A sensitivity analysis on the main influencing operating parameters for optimization. - Abstract: The purpose of this paper is to investigate the feasibility of integrating a proton exchange membrane fuel cell (PEMFC) system with a commercial greenhouse and assess the mutual benefits of such integration. The main objective is to recover the low quality waste heat of the PEMFC system in order to meet the thermal energy demand of a commercial greenhouse. In addition the PEMFC covers the some part of the greenhouse electrical demand. In this study an energy analysis has been performed in order to evaluate the energetic performance of the system. To achieve these aims, first, a system model has been developed using TRNSYS. Afterwards, a sensitivity analysis has been carried out varying the main influencing operating parameters in order to evaluate an optimal configuration of the system. In particular the influences of temperature and air stoichiometry have been investigated. The results show that a 3 kW fuel cell system is capable to cover approximately the 25% and 10% of the usual electricity and heat demands of a 1000 m 2 commercial greenhouse during a year, respectively

  9. Progress in R and D radiation processing of natural polymers in the Philippines

    International Nuclear Information System (INIS)

    Dela Rosa, A.; Abad, L.; Relleve, L.; Aranilla, C.; Cabalfin, E.; Bisnar, C.

    2007-01-01

    Radiation technology has emerged as an environment-friendly, commercially viable technology with broad applications that can essentially contribute to achieve the goal of sustainable development. Natural polymers are good raw materials since they are biodegradable, readily available in large quantity and at low cost. Radiation processing of natural polymers is a potential area to widen the prospect of industrial scale application of radiation technology in the Philippines. (author)

  10. Development of a coppice planting machine to commercial standards

    Energy Technology Data Exchange (ETDEWEB)

    Turton, J.S.

    2000-07-01

    This report gives details of the development work carried out on the Turton Engineering Coppice Planting machine in order to commercially market it. The background to the machine which plants single rows of cuttings from rods is traced,, and previous development work, design work, production of sub-assemblies and the assembly of modules, inspection and assembly, static trials, and commercial planting are examined. Further machine developments, proving trials, and recommendations for further work are discussed. Appendices address relationships applicable to vertical planting, the Turton short rotation cultivation machine rod format, estimated prices and charges, and a list of main suppliers. (UK)

  11. Understanding the impact of TV commercials: electrical neuroimaging.

    Science.gov (United States)

    Vecchiato, Giovanni; Kong, Wanzeng; Maglione, Anton Giulio; Wei, Daming

    2012-01-01

    Today, there is a greater interest in the marketing world in using neuroimaging tools to evaluate the efficacy of TV commercials. This field of research is known as neuromarketing. In this article, we illustrate some applications of electrical neuroimaging, a discipline that uses electroencephalography (EEG) and intensive signal processing techniques for the evaluation of marketing stimuli. We also show how the proper usage of these methodologies can provide information related to memorization and attention while people are watching marketing-relevant stimuli. We note that temporal and frequency patterns of EEG signals are able to provide possible descriptors that convey information about the cognitive process in subjects observing commercial advertisements (ads). Such information could be unobtainable through common tools used in standard marketing research. Evidence of this research shows how EEG methodologies could be employed to better design new products that marketers are going to promote and to analyze the global impact of video commercials already broadcast on TV.

  12. Commercial/industrial photovoltaic module and array requirement study. Low-cost solar array project engineering area

    Science.gov (United States)

    1981-01-01

    Design requirements for photovoltaic modules and arrays used in commercial and industrial applications were identified. Building codes and referenced standards were reviewed for their applicability to commercial and industrial photovoltaic array installation. Four general installation types were identified - integral (replaces roofing), direct (mounted on top of roofing), stand-off (mounted away from roofing), and rack (for flat or low slope roofs, or ground mounted). Each of the generic mounting types can be used in vertical wall mounting systems. This implies eight mounting types exist in the commercial/industrial sector. Installation costs were developed for these mounting types as a function of panel/module size. Cost drivers were identified. Studies were performed to identify optimum module shapes and sizes and operating voltage cost drivers. The general conclusion is that there are no perceived major obstacles to the use of photovoltaic modules in commercial/industrial arrays.

  13. Comparison of the applicability of commercial computer programs to study the thermodynamic stability of metal oxides

    International Nuclear Information System (INIS)

    Koukkari, P.; Olin, M.; Laitinen, T.; Sippola, H.

    1999-04-01

    The oxide films formed on primary circuit surfaces incorporate radioactive species from the coolant and influence different corrosion phenomena in nuclear power plants. One approach to improve the understanding on the formation and properties of these oxide films is to evaluate their thermodynamic stability. The aim of this work was to compare and demonstrate the applicability of different commercial thermodynamic computer programs to model the deposition of oxides containing iron, chromium and/or nickel in various nuclear power plant environments. The programs considered in this evaluation comprised the EQ3/6 program and a product group including such products as ChemSage, HSC (including SOLGASMIX and GIBBS), H+PLUS and ChemSheet. In the group the transfer of data between different products is relatively easy. The goal was to find out which programs can be applied to evaluate the stability of oxide films, but not to assess the absolute accuracy of the calculations. The evaluation was done by means of applying the programs to calculate the stability of pure and mixed oxides of iron, nickel and chromium on stainless steel both in WWER and BWR conditions at different temperatures and coolant compositions. The comparison showed that EQ3/6 is suitable for most thermodynamic calculations. EQ3/6 can be characterised as a professional tool, for which no commercial training is available. ChemSage is a versatile and reliable program, which can be well used together with HSC and H+PLUS. ChemSage is mainly a professional tool, while HSC is easier to operate by an occasional user. Commercial training and support is available for both ChemSage and HSC. ChemSheet has been designed to utilise the properties of ChemSage in a user-friendly spreadsheet environment. All the products tested calculate thermodynamic equilibrium. Thus they are suitable to characterise such conditions in which the formation of a certain phase is or becomes possible. On the other hand, the modelling of the

  14. Thermal Environment Evaluation in Commercial Kitchens of United States

    DEFF Research Database (Denmark)

    Simone, Angela; Olesen, Bjarne W.

    The indoor climate in commercial kitchens is often unsatisfactory and the working conditions can have a significant effect on employees’ comfort and productivity. The differences between type (fast food, dining, etc.) and climatic zone can have an influence on the environment conditions and on th......The indoor climate in commercial kitchens is often unsatisfactory and the working conditions can have a significant effect on employees’ comfort and productivity. The differences between type (fast food, dining, etc.) and climatic zone can have an influence on the environment conditions...... of defining the values of thermal comfort parameters in kitchens. It can also help to evaluate if the standardized methods are applicable for such non-uniform environment, like commercial kitchens. By using an established method and procedure for evaluating the indoor thermal comfort in commercial kitchens...... more than 100 kitchens environments in the United States were investigated in summer and winter. Results show the influence due to type of kitchen (fast food, casual, etc.) and climatic region. Physical measurement confirmed that communally the workers are exposed to a warm or hot environment...

  15. 78 FR 17875 - Commercial Driver's License Testing and Commercial Learner's Permit Standards

    Science.gov (United States)

    2013-03-25

    ... [Docket No. FMCSA-2007-27659] RIN 2126-AB59 Commercial Driver's License Testing and Commercial Learner's.... The 2011 final rule amended the commercial driver's license (CDL) knowledge and skills testing standards and established new minimum Federal standards for States to issue the commercial learner's permit...

  16. Nonlinear excitation fluorescence microscopy: source considerations for biological applications

    Science.gov (United States)

    Wokosin, David L.

    2008-02-01

    Ultra-short-pulse solid-state laser sources have improved contrast within fluorescence imaging and also opened new windows of investigation in biological imaging applications. Additionally, the pulsed illumination enables harmonic scattering microscopy which yields intrinsic structure, symmetry and contrast from viable embryos, cells and tissues. Numerous human diseases are being investigated by the combination of (more) intact dynamic tissue imaging of cellular function with gene-targeted specificity and electrophysiology context. The major limitation to more widespread use of multi-photon microscopy has been the complete system cost and added complexity above and beyond commercial camera and confocal systems. The current status of all-solid-state ultrafast lasers as excitation sources will be reviewed since these lasers offer tremendous potential for affordable, reliable, "turnkey" multiphoton imaging systems. This effort highlights the single box laser systems currently commercially available, with defined suggestions for the ranges for individual laser parameters as derived from a biological and fluorophore limited perspective. The standard two-photon dose is defined by 800nm, 10mW, 200fs, and 80Mhz - at the sample plane for tissue culture cells, i.e. after the full scanning microscope system. Selected application-derived excitation wavelengths are well represented by 700nm, 780nm, ~830nm, ~960nm, 1050nm, and 1250nm. Many of the one-box lasers have fixed or very limited excitation wavelengths available, so the lasers will be lumped near 780nm, 800nm, 900nm, 1050nm, and 1250nm. The following laser parameter ranges are discussed: average power from 200mW to 2W, pulse duration from 70fs to 700fs, pulse repetition rate from 20MHz to 200MHz, with the laser output linearly polarized with an extinction ratio at least 100:1.

  17. 77 FR 26989 - Commercial Driver's License Testing and Commercial Learner's Permit Standards

    Science.gov (United States)

    2012-05-08

    ... [Docket No. FMCSA-2007-27659] RIN 2126-AB02 Commercial Driver's License Testing and Commercial Learner's... effective on July 8, 2011. That final rule amended the commercial driver's license (CDL) knowledge and skills testing standards and established new minimum Federal standards for States to issue the commercial...

  18. Modelling the number of viable vegetative cells of Bacillus cereus passing through the stomach

    NARCIS (Netherlands)

    Wijnands, L.M.; Pielaat, A.; Dufrenne, J.B.; Zwietering, M.H.; Leusden, van F.M.

    2009-01-01

    Aims: Model the number of viable vegetative cells of B. cereus surviving the gastric passage after experiments in simulated gastric conditions. Materials and Methods: The inactivation of stationary and exponential phase vegetative cells of twelve different strains of Bacillus cereus, both mesophilic

  19. STRUCTURE OF MODELS FOR AGGREGATE ASSESSMENT OF FINANCIAL RISK COMMERCIAL BANKS

    OpenAIRE

    G. Kryshtal

    2016-01-01

    Conceptual approaches use a structural model for assessment of financial risk commercial banks, namely the risk measurement in combination: a comparison of its capital, calculated based on the standard approach of Basel II advanced approaches of Basel II and the structural model. Analysis of the application of the model in a economics crisis situation, such as the capital adequacy of the commercial banks. Deals with a unified approach to the choice of measure and its risk parameters to measur...

  20. Space commercialization: Launch vehicles and programs; Symposium on Space Commercialization: Roles of Developing Countries, Nashville, TN, Mar. 5-10, 1989, Technical Papers

    International Nuclear Information System (INIS)

    Shahrokhi, F.; Greenberg, J.S.; Al-saud, Turki.

    1990-01-01

    The present volume on progress in astronautics and aeronautics discusses the advent of commercial space, broad-based space education as a prerequisite for space commercialization, and obstacles to space commercialization in the developing world. Attention is given to NASA directions in space propulsion for the year 2000 and beyond, possible uses of the external tank in orbit, power from the space shuttle and from space for use on earth, Long-March Launch Vehicles in the 1990s, the establishment of a center for advanced space propulsion, Pegasus as a key to low-cost space applications, legal problems of developing countries' access to space launch vehicles, and international law of responsibility for remote sensing. Also discussed are low-cost satellites and satellite launch vehicles, satellite launch systems of China; Raumkurier, the German recovery program; and the Ariane transfer vehicle as logistic support to Space Station Freedom