Aslanian, Daniel; Moulin, Maryline
P>Torsvik et al. recently presented a revised model for the opening of the South Atlantic Ocean. According to these authors, this new plate tectonic model is internally consistent and consistent with globally balanced plate motion solutions and takes into account realistic intraplate deformation. However, this model shows a number of kinematic and geological problems that we underline here, together with some comparisons with the new kinematic model recently proposed by Moulin et al.
Näitus "Inimene ja maastik". Eksponeeritud trükitehnikas graafika ja fotod, valik ühest kunstikogust. Kunstnikest nimetatud Günther Uecker ja Heinz Stein (Saksamaa), Trond-Ivar Bergsmo, Nils Skare (Norra), Gunars Binde (Läti)
Reinfjell, Trude; Jozefiak, Thomas
Livskvalitetsmålet PedsQLTM ble utviklet av James W. Varni, og første gang publisert på engelsk i 1999. Trude Reinfjell og Trond H. Diseth står bak den norske oversettelsen med publisering i 2006. Oversettelsen ble gjennomført etter internasjonale retningslinjer og godkjent av originalforfatteren. Målgruppen er barn i førskole- og skolealder, samt ungdom og unge voksne. PedsQLTM foreligger i fem versjoner tilpasset alder og informant (barneversjonen for 5-7 år, tenåringsversjonen for 8-12 år,...
Adela Sanz Cañibano; María Goretti Morón Nozaleda; Francisco Chicharro Lezcano; Iñaki Markez; Eudoxia Gay Pamos; Fernando Mansilla Izquiedo; Mauricio Jalón; Alicia Merisi; Andrea Rubín; Juan Medrano
VV AA. La histeria antes de Freud. (Laura Martín López-Andrade) José Luis Peset. Las melancolías de Sancho. Humores y pasiones entre Huarte y Pinel. (Alicia Merisi) David Simón Lorda. Médicos Ourensanos Represaliados en la Guerra Civil y en la Posguerra. Historias de la “Longa Noite de Pedra” (Alexandre García Caballero) Ángel Cagigas. Arte Demente. (Ana Hernández) Salomon Resnik. Tiempos de glaciaciones. Viaje al mundo de la locura. (Reda Rhamani) Gerd-Ragna Bloch Thorsen, Trond Gronnestad, ...
Akça, Gökçen; Yerdelen, Deniz; Balcı, Mustafa Kemal; Uysal, Hilmi
We aimed to explore axonal excitability parameters in patients with diabetes mellitus (DM) and polyneuropathy (PNP) as well as those without PNP. We used the short TROND protocol by QTRAC to measure axonal excitability parameters (strength-duration time constant (SDTC), rheobase, etc.) in 12 healthy subjects and 14 DM patients with PNP and 10 DM patients without PNP. The short TROND protocol was performed before and after 20min of deep hyperventilation in healthy subjects and patients with DM. Also, venous blood pH and partial pressure of O2 and CO2 were recorded before hyperventilation (HPV) and after 20min of HPV. A "hyperventilation score" was evaluated before and after HPV. When the values of DM with PNP group and control group before HPV were compared, SDTC and latency were statistically significant. Comparing the values of the excitability parameters after HPV showed statistically significant changes in the SDTC, rheobase, and refractoriness at 2.5ms in controls and DM patients without PNP. HPV resulted in no changes in SDTC in DM patients with PNP. The results of this study suggest that patients with DM and healthy subjects have different responses to HPV, and pH changes have different effects on diabetic PNP compared with healthy controls and DM patients without PNP. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Casanova, I; Diaz, A; Pinto, S; de Carvalho, M
The technique of threshold tracking to test axonal excitability gives information about nodal and internodal ion channel function. We aimed to investigate variability of the motor excitability measurements in healthy controls, taking into account age, gender, body mass index (BMI) and small changes in skin temperature. We examined the left median nerve of 47 healthy controls using the automated threshold-tacking program, QTRAC. Statistical multiple regression analysis was applied to test relationship between nerve excitability measurements and subject variables. Comparisons between genders did not find any significant difference (P>0.2 for all comparisons). Multiple regression analysis showed that motor amplitude decreases with age and temperature, stimulus-response slope decreases with age and BMI, and that accommodation half-time decrease with age and temperature. The changes related to demographic features on TRONDE protocol parameters are small and less important than in conventional nerve conduction studies. Nonetheless, our results underscore the relevance of careful temperature control, and indicate that interpretation of stimulus-response slope and accommodation half-time should take into account age and BMI. In contrast, gender is not of major relevance to axonal threshold findings in motor nerves. Copyright © 2014 Elsevier Masson SAS. All rights reserved.
Gueguen, Antoine; Jardel, Claude; Polivka, Marc; Tan, S Veronica; Gray, Françoise; Vignal, Catherine; Lombès, Anne; Gout, Olivier; Bostock, Hugh
To explore potential spreading to peripheral nerves of the mitochondrial dysfunction in chronic progressive external ophthalmoplegia (CPEO) by assessing axonal excitability. CPEO patients (n=13) with large size deletion of mitochondrial DNA and matching healthy controls (n=22) were included in a case-control study. Muscle strength was quantified using MRC sum-score and used to define two groups of patients: CPEO-weak and CPEO-normal (normal strength). Nerve excitability properties of median motor axons were assessed with the TROND protocol and changes interpreted with the aid of a model. Alterations of nerve excitability strongly correlated with scores of muscle strength. CPEO-weak displayed abnormal nerve excitability compared to CPEO-normal and healthy controls, with increased superexcitability and responses to hyperpolarizing current. Modeling indicated that the CPEO-weak recordings were best explained by an increase in the 'Barrett-Barrett' conductance across the myelin sheath. CPEO patients with skeletal weakness presented sub-clinical nerve excitability changes, which were not consistent with axonal membrane depolarization, but suggested Schwann cell involvement. This study provides new insights into the spreading of large size deletion of mitochondrial DNA to Schwann cells in CPEO patients. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.
Full Text Available Yngvar Nilssen,1 Trond-Eirik Strand,1 Robert Wiik,2 Inger Johanne Bakken,3 Xue Qin Yu,4,5 Dianne L O'Connell,4–7 Bjørn Møller1 1Department of Registration, Cancer Registry of Norway, Oslo, 2Norwegian Patient Register Department, Norwegian Directorate of Health, Trondheim, 3Norwegian Institute of Public Health, Oslo, Norway; 4Cancer Research Division, Cancer Council NSW, 5School of Public Health, University of Sydney, 6School of Public Health and Community Medicine, University of New South Wales, Sydney, 7School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia Objective: To construct an updated comorbidity index (Patient Register Index [PRI] using national data collections from Norway and compare its predictive ability of 1-year mortality with the Charlson Comorbidity Index (CCI. Materials and methods: Data regarding over 1.11 million patients registered in the Norwegian Patient Register in 2010 and 2011 were used to construct the PRI. The PRI was evaluated by comparing its model fit and discrimination with the CCI. Results: Compared with the CCI, the PRI weights decreased for six, increased for four, and were unchanged for seven diseases. When the PRI was added to the model including age and sex, the age effects were reduced by up to 38% for patients older than 50 years. All measures of model fit improved for the PRI model. Conclusion: Adjustment for comorbidity is especially important for patients 50 years of age or older, and its effect on 1-year mortality is almost comparable to the age effect. The PRI is based on more recent data than the CCI, and is more representative of the general population due to its construction. Keywords: comorbidity, National Patient Register, Charlson Comorbidity Index, predictive ability, patient-register index, prognostic value
Full Text Available Knut A Hestad,1–3 Siri Weider,3,4 Kristian Bernhard Nilsen,5–7 Marit Sæbø Indredavik,8,9 Trond Sand7,10 1Department of Research, Innlandet Hospital Trust, Brumunddal, Norway; 2Department of Public Health, Hedmark University of Applied Sciences, Elverum, Norway; 3Department of Psychology, Faculty of Social Sciences and Technology Management, Norwegian University of Science and Technology (NTNU, Trondheim, Norway; 4Department of Psychiatry, Specialised Unit for Eating Disorder Patients, Levanger Hospital, Health Trust Nord-Trøndelag, Levanger, Norway; 5Department of Neuroscience, Norwegian University of Science and Technology (NTNU, Trondheim, Norway; 6Department of Work Psychology and Physiology, National Institute of Occupational Health, Oslo, Norway; 7Department of Neurology, Section for Clinical Neurophysiology, Oslo University Hospital, Ullevål, Oslo, Norway; 8Regional Centre for Child and Youth Mental Health and Child Welfare, Faculty of Medicine, Norwegian University of Science and Technology (NTNU, Trondheim, Norway; 9Department of Child and Adolescent Psychiatry, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; 10Department of Neurology and Clinical Neurophysiology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway Objective: To conduct a blind study of quantitative electroencephalogram-band amplitudes in patients with anorexia nervosa (AN and healthy controls.Methods: Twenty-one patients with AN and 24 controls were examined with eyes-closed 16-channel electroencephalogram. Main variables were absolute alpha, theta, and delta amplitudes in frontal, temporal, and posterior regions.Results: There were no significant differences between the AN patients and controls regarding absolute regional band amplitudes in µV. Borderline significance was found for anterior theta (P=0.051. Significantly increased left and right frontal electrode theta amplitude was found in AN patients (F3, P=0.014; F4, P