Containment-emergency-sump performance. Technical findings related to Unresolved Safety Issue A-43

International Nuclear Information System (INIS)

1983-04-01

This report summarizes key technical findings related to the Unresolved Safety Issue A-43, Containment Emergency Sump Performance, and provides recommendations for resolution of attendant safety issues. The key safety questions relate to: (a) effects of insulation debris on sump performance; (b) sump hydraulic performance as determined by design features, submergence, and plant induced effects, and (c) recirculation pump performance wherein air and/or particulate ingestion can occur. The technical findings presented in this report provide information relevant to the design and performance evaluation of the containment emergency sump

Status of safety issues at licensed power plants: TMI Action Plan requirements; unresolved safety issues; generic safety issues; other multiplant action issues

International Nuclear Information System (INIS)

1993-12-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, the NRC established a program for publishing an annual report on the status of licensee implementation and NRC verification of safety issues in major NRC requirements areas. This information was initially compiled and reported in three NUREG-series volumes. Volume 1, published in March 1991, addressed the status of Three Mile Island (TMI) Action Plan Requirements. Volume 2, published in May 1991, addressed the status of unresolved safety issues (USIs). Volume 3, published in June 1991, addressed the implementation and verification status of generic safety issues (GSIs). The first annual supplement, which combined these volumes into a single report and presented updated information as of September 30, 1991, was published in December 1991. The second annual supplement, which provided updated information as of September 30, 1992, was published in December 1992. Supplement 2 also provided the status of licensee implementation and NRC verification of other multiplant action (MPA) issues not related to TMI Action Plan requirements, USIs, or GSIs. This third annual NUREG report, Supplement 3, presents updated information as of September 30, 1993. This report gives a comprehensive description of the implementation and verification status of TMI Action Plan requirements, safety issues designated as USIs, GSIs, and other MPAs that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. Additionally, this report serves as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

Unresolved Safety Issue A-46 - seismic qualification of equipment in operating plants

International Nuclear Information System (INIS)

Anderson, N.

1985-01-01

Seismic Qualification of Equipment in Operating Plants was designated as an Unresolved Safety Issue (USI) in December, 1980. The USI A-46 program was developed in early 1981 to investigate the adequacy of mechanical and electrical equipment in operating plants to withstand a safe shutdown earthquake. The approach taken was to develop viable, cost effective alternatives to current seismic qualification licensing requirements which could be applied to operating nuclear power plants. The tasks investigated include: (1) identification of seismic sensitive systems and equipment; (2) assessment of adequacy of existing seismic qualification methods; (3) development and assessment of in-situ test procedures to assist in qualification of equipment; (4) seismic qualification of equipment using seismic experience data; and (5) development of methods to generate generic floor response spectra. Progress to date and plans for completion of resolution are reported

Status of safety issues at licensed power plants: TMI Action Plan requirements, unresolved safety issues, generic safety issues, other multiplant action issues. Supplement 4

International Nuclear Information System (INIS)

1994-12-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, the NRC established a program for publishing an annual report on the status of licensee implementation and NRC verification of safety issues in major NRC requirements areas. This information was initially compiled and reported in three NUREG-series volumes. Volume 1, published in March 1991, addressed the status of Three Mile Island (TMI) Action Plan Requirements. Volume 2, published in May 1991, addressed the status of unresolved safety issues (USIs). Volume 3, published in June 1991, addressed the implementation and verification status of generic safety issues (GSIs). The first annual supplement, which combined these volumes into a single report and presented updated information as of September 30, 1991, was published in December 1991. The second annual supplement, which provided updated information as of September 30, 1992, was published in December 1992. Supplement 2 also provided the status of licensee implementation and NRC verification of other multiplant action (MPA) issues not related to TMI Action Plan requirements, USIs, or GSIs. Supplement 3 gives status as of September 30, 1993. This annual report, Supplement 4, presents updated information as of September 30, 1994. This report gives a comprehensive description of the implementation and verification status of TMI Action Plan requirements, safety issues designated as USIs, GSIs, and other MPAs that have been resolved and involve implementation of an action or actions by licensees. This report makes the information available to other interested parties, including the public. Additionally, this report serves as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues until requirements are approved for imposition at licensed plants or until the NRC issues a request for action by licensees

Quantum dots in nanomedicine: recent trends, advances and unresolved issues

International Nuclear Information System (INIS)

Volkov, Yuri

2015-01-01

The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including “classical” semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems. - Highlights: • New types of nanomaterials have been recently added to the category of QDs with a potential in nanomedicine. • Within the main nanomedicine domains, best progress has been achieved with QDs for diagnostic tools. • Further studies are required for the theranostic QDs-based leads to reach clinical translation.

Quantum dots in nanomedicine: recent trends, advances and unresolved issues

Energy Technology Data Exchange (ETDEWEB)

Volkov, Yuri, E-mail: yvolkov@tcd.ie

2015-12-18

The review addresses the current state of progress in the use of ultra-small nanoparticles from the category of quantum dots (QDs), which presently embraces a widening range of nanomaterials of different nature, including “classical” semiconductor groups III-V and II-VI nanocrystals, along with more recently emerged carbon, silicon, gold and other types of nanoparticles falling into this class of nanomaterials due to their similar physical characteristics such as small size and associated quantum confinement effects. A diverse range of QDs applications in nanomedicine has been extensively summarised previously in numerous publications. Therefore, this review is not intended to provide an all-embracing survey of the well documented QDs uses, but is rather focused on the most recent emerging developments, concepts and outstanding unresolved problematic and sometimes controversial issues. Over 125 publications are overviewed and discussed here in the context of major nanomedicine domains, i.e. medical imaging, diagnostics, therapeutic applications and combination of them in multifunctional theranostic systems. - Highlights: • New types of nanomaterials have been recently added to the category of QDs with a potential in nanomedicine. • Within the main nanomedicine domains, best progress has been achieved with QDs for diagnostic tools. • Further studies are required for the theranostic QDs-based leads to reach clinical translation.

Comment 4 - policy for sustainable development: Some unresolved issues

International Nuclear Information System (INIS)

Ruttan, V.W.

1992-01-01

We are now in the midst of the third wave of social concern since World War II about the implications of natural resource availability and environmental change for the sustainability of improvements in human well-being. The first wave of concern in the late 1940s and early 1950s focused primarily on the quantitative relationship between resource availability and economic growth. The response to this first wave of concern was technical change in raw material production. The second wave of concern, in the late 1960s and early 1970s, focused on the rising demand for assimilation by the environment of residuals derived from growth in commodity production and consumption - primarily at the local and regional level. Since the mid 1980s, these two early concerns have been supplemented by a third. This more recent concern centers around the implications for environmental quality, food production, and human health of a series of environmental changes such as global warming, ozone depletion, acid rain, and others that are occurring on a transnational scale. Before actions to resolve these more recent challenges to sustainable economic growth are taken, a number of unresolved issues must be confronted to allow a commitment to this resolution to be translated into an internally coherent reform agenda. In this note, he discuss three of these issues

Regulatory analysis for the resolution of Unresolved Safety Issue A-44, Station Blackout. Draft report

International Nuclear Information System (INIS)

Rubin, A.M.

1986-01-01

''Station Blackout'' is the complete loss of alternating current (ac) electric power to the essential and nonessential buses in a nuclear power plant; it results when both offsite power and the onsite emergency ac power systems are unavailable. Because many safety systems required for reactor core decay heat removal and containment heat removal depend on ac power, the consequences of a station blackout could be severe. Because of the concern about the frequency of loss of offsite power, the number of failures of emergency diesel generators, and the potentially severe consequences of a loss of all ac power, ''Station Blackout'' was designated as Unresolved Safety Issue (USI) A-44. This report presents the regulatory analysis for USI A-44. It includes: (1) a summary of the issue, (2) the proposed technical resolution, (3) alternative resolutions considered by the Nuclear Regulatory Commission (NRC) staff, (4) an assessment of the benefits and costs of the recommended resolution, (5) the decision rationale, and (6) the relationship between USI A-44 and other NRC programs and requirements

Identification of new unresolved safety issues relating to nuclear power plants - special report to Congress. Congressional report

International Nuclear Information System (INIS)

1981-03-01

As a result of NRC staff review and extended collegial consultations and investigations within the NRC, the Commission has designated four new Unresolved Safety Issues (USIs). This report describes the process used to evaluate the large number of concerns and recommendations which resulted from the major investigations of the Three Mile Island-2 accident as well as other events and investigations of the past year, and the report identifies the four new USIs selected as follows: (1) Shutdown decay heat removal requirements (Task A-45); (2) Seismic qualification of equipment in operating plants (Task A-46); (3) Safety implications of control systems (Task A-47); and (4) Hydrogen control measures and effects of hydrogen burns on safety equipment (Task A-48). Appendix A of the report presents an expanded discussion of each new USI including issue definition, a preliminary discussion of the action plan and a basis for continued plant operations and licensing. Appendix B of the report provides a brief discussion of each of the candidate safety issues not designated as an USI

Progress Towards an LES Wall Model Including Unresolved Roughness

Science.gov (United States)

Craft, Kyle; Redman, Andrew; Aikens, Kurt

2015-11-01

Wall models used in large eddy simulations (LES) are often based on theories for hydraulically smooth walls. While this is reasonable for many applications, there are also many where the impact of surface roughness is important. A previously developed wall model has been used primarily for jet engine aeroacoustics. However, jet simulations have not accurately captured thick initial shear layers found in some experimental data. This may partly be due to nozzle wall roughness used in the experiments to promote turbulent boundary layers. As a result, the wall model is extended to include the effects of unresolved wall roughness through appropriate alterations to the log-law. The methodology is tested for incompressible flat plate boundary layers with different surface roughness. Correct trends are noted for the impact of surface roughness on the velocity profile. However, velocity deficit profiles and the Reynolds stresses do not collapse as well as expected. Possible reasons for the discrepancies as well as future work will be presented. This work used the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by National Science Foundation grant number ACI-1053575. Computational resources on TACC Stampede were provided under XSEDE allocation ENG150001.

Evaluation of water-hammer experience in nuclear power plants. Technical findings relevant to Unresolved Safety Issue A-1

International Nuclear Information System (INIS)

Serkiz, A.W.

1983-05-01

This report summarizes key technical findings relevant to the Unresolved Safety Issue A-1, Water Hammer. These findings were derived from studies of reported water hammer occurrences and underlying causes and provide key insights into means to minimize or eliminate further water hammer occurrences. It should also be noted that this report does not represent a substitute for current rules and regulations

Chalk Catchment Transit Time: Unresolved Issues

Energy Technology Data Exchange (ETDEWEB)

Darling, W. G.; Gooddy, D. C. [British Geological Survey, Crowmarsh Gifford, Wallingford, Oxfordshire (United Kingdom); Barker, J. A. [School of Civil Engineering and the Environment, University of Southampton, Southampton (United Kingdom); Robinson, M. [Centre for Ecology and Hydrology, Crowmarsh Gifford, Wallingford, Oxfordshire (United Kingdom)

2013-07-15

The mean transit time (MTT) of a catchment is the average residence time of water from rainfall to river outflow at the foot of the catchment. As such, MTT has important water quality as well as resource implications. Many catchments worldwide have been measured for MTT using environmental isotopes, yet the Chalk, an important aquifer in NW Europe, has received little attention in this regard. The catchment of the River Lambourn in southern England has been intermittently studied since the 1960s using isotopic methods. A tritium peak measured in the river during the 1970s indicates an apparent MTT of {approx}15 years, but the thick unsaturated zone (average {approx}50 m) of the catchment suggests that the MTT should be much greater because of the average downward movement through the Chalk of {approx}1 m/a consistently indicated by tritium and other tracers. Recent work in the catchment using SF{sub 6} as a residence time indicator has given groundwater ages in the narrow range 11-18 yrs, apparently supporting the river tritium data but in conflict with the unsaturated zone data even allowing for a moderate proportion of rapid bypass flow. The MTT of the catchment remains unresolved for the time being. (author)

Regulatory analysis for resolution of Unresolved Safety Issue A-46, seismic qualification of equipment in operating plants

International Nuclear Information System (INIS)

Chang, T.Y.; Anderson, N.R.

1987-02-01

The margin of safety provided in existing nuclear power plant equipment to resist seismically induced loads and perform required safety functions may vary considerably, because of significant changes in design criteria and methods for the seismic qualification of equipment over the years. Therefore, the seismic qualification of equipment in operating plants must be reassessed to determine whether requalification is necessary. The objective of technical studies performed under Task Action Plan A-46 was to establish an explicit set of guidelines and acceptance criteria to judge the adequacy of equipment under seismic loading at all operating plants, in lieu of requiring these plants to meet the criteria that are applied to new plants. This report presents the regulatory analysis for Unresolved Safety Issue (USI) A-46. It includes: Statement of the Problem; the Objective of USI A-46; a Summary of A-46 Tasks; a Proposed Implementation Procedure; a Value-Impact Analysis; Application of the Backfit Rule; 10 CFR 50.109; Implementation; and Operating Plants To Be Reviewed to USI A-46 Requirements

Evaluation of Station Blackout accidents at nuclear power plants. Technical findings related to Unresolved Safety Issue A-44. Draft report for comment

International Nuclear Information System (INIS)

Baranowsky, P.W.

1985-05-01

''Station Blackout,'' which is the complete loss of alternating current (ac) electrical power in a nuclear power plant, has been designated as Unresolved Safety Issue A-44. Because many safety systems required for reactor core decay heat removal and containment heat removal depend on ac power, the consequences of a station blackout could be severe. This report documents the findings of technical studies performed as part of the program to resolve this issue. The important factors analyzed include: the frequency of loss of offsite power; the probability that emergency or onsite ac power supplies would be unavailable; the capability and reliability of decay heat removal systems independent of ac power; and the likelihood that offsite power would be restored before systems that cannot operate for extended periods without ac power fail, thus resulting in core damage. This report also addresses effects of different designs, locations, and operational features on the estimated frequency of core damage resulting from station blackout events

Oxidative stress and life histories: unresolved issues and current needs.

Science.gov (United States)

Speakman, John R; Blount, Jonathan D; Bronikowski, Anne M; Buffenstein, Rochelle; Isaksson, Caroline; Kirkwood, Tom B L; Monaghan, Pat; Ozanne, Susan E; Beaulieu, Michaël; Briga, Michael; Carr, Sarah K; Christensen, Louise L; Cochemé, Helena M; Cram, Dominic L; Dantzer, Ben; Harper, Jim M; Jurk, Diana; King, Annette; Noguera, Jose C; Salin, Karine; Sild, Elin; Simons, Mirre J P; Smith, Shona; Stier, Antoine; Tobler, Michael; Vitikainen, Emma; Peaker, Malcolm; Selman, Colin

2015-12-01

Life-history theory concerns the trade-offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life-history trade-offs, but the details remain obscure. As life-history theory concerns aspects of investment in the soma that influence survival, understanding the physiological basis of life histories is related, but not identical, to understanding the process of aging. One idea from the field of aging that has gained considerable traction in the area of life histories is that life-history trade-offs may be mediated by free radical production and oxidative stress. We outline here developments in this field and summarize a number of important unresolved issues that may guide future research efforts. The issues are as follows. First, different tissues and macromolecular targets of oxidative stress respond differently during reproduction. The functional significance of these changes, however, remains uncertain. Consequently there is a need for studies that link oxidative stress measurements to functional outcomes, such as survival. Second, measurements of oxidative stress are often highly invasive or terminal. Terminal studies of oxidative stress in wild animals, where detailed life-history information is available, cannot generally be performed without compromising the aims of the studies that generated the life-history data. There is a need therefore for novel non-invasive measurements of multi-tissue oxidative stress. Third, laboratory studies provide unrivaled opportunities for experimental manipulation but may fail to expose the physiology underpinning life-history effects, because of the benign laboratory environment. Fourth, the idea that oxidative stress might underlie life-history trade-offs does not make specific enough predictions that are amenable to testing. Moreover, there is a paucity of good alternative theoretical models on which contrasting

Resolution of Unresolved Safety Issue A-48, ''Hydrogen control measures and effects of hydrogen burns on safety equipment''

International Nuclear Information System (INIS)

Ferrell, C.M.; Soffer, L.

1989-09-01

Unresolved Safety Issue (USI) A-48 arose as a result of the large amount of hydrogen generated and burned within containment during the Three Mile Island accident. This issue covers hydrogen control measures for recoverable degraded-core accidents for all boiling-water reactors (BWRs) and those pressurized-water reactors (PWRs) with ice-condenser containments. The Commission and the nuclear industry have sponsored extensive research in this area, which has led to significant revision of the Commission's hydrogen control regulations, given in Title 10, Code of Federal Regulations, Part 50 (10 CFR 50), Section 50.44. BWRs having Mark I and II containments are presently required to operate with inerted containment atmospheres that effectively prevent hydrogen combustion. BWRs with Mark III containments and PWRs with ice-condenser containments are now required to be equipped with hydrogen control systems to protect containment integrity and safety systems inside containment. Industry has chosen to use hydrogen igniter systems to burn hydrogen produced in a controlled fashion to prevent damage. An independent review by a Committee of the National Research Council concluded that, for most accident scenarios, current regulatory requirements make it highly unlikely that hydrogen detonation would be the cause of containment failure. On the basis of the extensive research effort conducted and current regulatory requirements, including their implementation, the staff concludes that no new regulatory guidance on hydrogen control for recoverable degraded-core accidents for these types of plants is necessary and that USI A-48 is resolved

Sexual Harassment: A problem unresolved!

Directory of Open Access Journals (Sweden)

N Vanishree

2013-01-01

Full Text Available Sexual harassment is a highly prevalent form of gender-based discrimination and sexual exploitation in the workplace and academic environment. In the dental field, there are a few studies regarding sexual harassment among the patients, professors and claims of their students. There is a silence of consent surrounding sexual harassment. It is clearly an issue about which the practicing dentists need to be informed in order to provide knowledgeable assessment and treatment for all patients. Dentists also have a role in advocacy, expert consultation or testimony, research and prevention through education and training. It is a fact that sexual harassment is very commonly encountered by almost everyone especially women. It is the most unresolved and under recognized problem of today especially when professionals are concerned. Preventing sexual harassment requires a considerable investment of time and personnel. This paper reviews the topic of sexual harassment as a problem from its legal aspects and recommendations for further steps to resolve this issue in dentistry.

Containment Emergency Sump Performance. Technical findings related to Unresolved Safety Issue A-43. Revision 1

International Nuclear Information System (INIS)

1985-10-01

This report summarizes key technical findings related to Unresolved Safety Issue (USI) A-43, Containment Emergency Sump Performance. Both BWRs and PWRs are considered in this report. Emergency core cooling systems require a clean, reliable water source to maintain long-term recirculation following a loss-of-coolant accident (LOCA). PWRs rely on the containment emergency sump to provide such a water supply to residual heat removal pumps and containment spray pumps. BWRs rely on pump suction intakes in the suppression pool or wet well to provide water to residual heat removal and core spray systems. Thus, the technical findings in this report provide information on post-LOCA recirculation. These findings have been derived from extensive experimental studies, generic plant studies, and assessments of sumps used for long-term cooling. Results of hydraulic tests have shown that the potential for air ingestion is less severe than previously hypothesized. The effects of debris blockage on NPSH margin must be dealt with on a plant-specific basis. These findings have been used to develop revisions to Regulatory Guide 1.82 and Standard Review Plan Section 6.2.2 (NUREG-0800)

Unresolved mourning, supernatural beliefs and dissociation: a mediation analysis.

Science.gov (United States)

Thomson, Paula; Jaque, S Victoria

2014-01-01

Unresolved mourning is marked by disorganized behavior and states of mind. In this study, we speculated that pathological dissociation would mediate the effects of unresolved mourning on supernatural beliefs. This hypothesis was determined based on findings that indicate an association between higher levels of dissociation, stronger beliefs in the supernatural and unresolved mourning. We examined two groups of participants, one classified as non-unresolved (non-U) (n = 56) and the other as unresolved (n = 26) (U) with respect to past loss/trauma as measured by the Adult Attachment Interview (AAI). Two self-report instruments were administered to measure supernatural beliefs and dissociation. As hypothesized, the multivariate analysis of variance indicated mean differences between the two groups. The unresolved group had greater belief in the supernatural and more pathological dissociative processes. The mediation analysis demonstrated that pathological dissociation fully mediated the effects of unresolved mourning on supernatural beliefs.

Detecting unresolved binary stars in Euclid VIS images

Science.gov (United States)

Kuntzer, T.; Courbin, F.

2017-10-01

Measuring a weak gravitational lensing signal to the level required by the next generation of space-based surveys demands exquisite reconstruction of the point-spread function (PSF). However, unresolved binary stars can significantly distort the PSF shape. In an effort to mitigate this bias, we aim at detecting unresolved binaries in realistic Euclid stellar populations. We tested methods in numerical experiments where (I) the PSF shape is known to Euclid requirements across the field of view; and (II) the PSF shape is unknown. We drew simulated catalogues of PSF shapes for this proof-of-concept paper. Following the Euclid survey plan, the objects were observed four times. We propose three methods to detect unresolved binary stars. The detection is based on the systematic and correlated biases between exposures of the same object. One method is a simple correlation analysis, while the two others use supervised machine-learning algorithms (random forest and artificial neural network). In both experiments, we demonstrate the ability of our methods to detect unresolved binary stars in simulated catalogues. The performance depends on the level of prior knowledge of the PSF shape and the shape measurement errors. Good detection performances are observed in both experiments. Full complexity, in terms of the images and the survey design, is not included, but key aspects of a more mature pipeline are discussed. Finding unresolved binaries in objects used for PSF reconstruction increases the quality of the PSF determination at arbitrary positions. We show, using different approaches, that we are able to detect at least binary stars that are most damaging for the PSF reconstruction process. The code corresponding to the algorithms used in this work and all scripts to reproduce the results are publicly available from a GitHub repository accessible via http://lastro.epfl.ch/software

Self-shielding effect in unresolved resonance data in JENDL-4.0

International Nuclear Information System (INIS)

Konno, Chikara; Takakura, Kosuke; Ochiai, Kentaro; Sato, Satoshi; Kato, Yoshinari

2012-01-01

At International Conference on Nuclear Data for Science and Technology in 2007 we pointed out that most of unresolved resonance data in JENDL-3.3 have a problem related to self-shielding correction. Here with a simple calculation model we have investigated whether the latest JENDL, JENDL-4.0, was improved for the problem or not. The results suggest that unresolved resonance data in JENDL-4.0 have no problem, but it seems that self-shielding effects for the unresolved resonance data in JENDL-4.0 are too large. New benchmark experiments for unresolved resonance data are strongly recommended in order to verify unresolved resonance data. (author)

Error due to unresolved scales in estimation problems for atmospheric data assimilation

Science.gov (United States)

Janjic, Tijana

The error arising due to unresolved scales in data assimilation procedures is examined. The problem of estimating the projection of the state of a passive scalar undergoing advection at a sequence of times is considered. The projection belongs to a finite- dimensional function space and is defined on the continuum. Using the continuum projection of the state of a passive scalar, a mathematical definition is obtained for the error arising due to the presence, in the continuum system, of scales unresolved by the discrete dynamical model. This error affects the estimation procedure through point observations that include the unresolved scales. In this work, two approximate methods for taking into account the error due to unresolved scales and the resulting correlations are developed and employed in the estimation procedure. The resulting formulas resemble the Schmidt-Kalman filter and the usual discrete Kalman filter, respectively. For this reason, the newly developed filters are called the Schmidt-Kalman filter and the traditional filter. In order to test the assimilation methods, a two- dimensional advection model with nonstationary spectrum was developed for passive scalar transport in the atmosphere. An analytical solution on the sphere was found depicting the model dynamics evolution. Using this analytical solution the model error is avoided, and the error due to unresolved scales is the only error left in the estimation problem. It is demonstrated that the traditional and the Schmidt- Kalman filter work well provided the exact covariance function of the unresolved scales is known. However, this requirement is not satisfied in practice, and the covariance function must be modeled. The Schmidt-Kalman filter cannot be computed in practice without further approximations. Therefore, the traditional filter is better suited for practical use. Also, the traditional filter does not require modeling of the full covariance function of the unresolved scales, but only

NRC integrated program for the resolution of Unresolved Safety Issues A-3, A-4 and A-5 regarding steam generator tube integrity: Final report

International Nuclear Information System (INIS)

1988-09-01

This report presents the results of the NRC integrated program for the resolution of Unresolved Safety Issues (USIs) A-3, A-4, and A-5 regarding steam generator tube integrity. A generic risk assessment is provided and indicates that risk from steam generator tube rupture (SGTR) events is not a significant contributor to total risk at a given site, nor to the total risk to which the general public is routinely exposed. This finding is considered to be indicative of the effectiveness of licensee programs and regulatory requirements for ensuring steam generator tube integrity in accordance with 10 CFR 50, Appendices A and B. This report also identifies a number of staff-recommended actions that the staff finds can further improve the effectiveness of licensee programs in ensuring the integrity of steam generator tubes and in mitigating the consequences of an SGTR. As part of the integrated program, the staff issued Generic Letter 85-02 encouraging licensees of pressurized water reactors (PWRs) to upgrade their programs, as necessary, to meet the intent of the staff-recommended actions; however, such actions do not constitute NRC requirements. In addition, this report describes a number of ongoing staff actions and studies involving steam generator issues which are being pursued to provide added assurance that risk from SGTR events will continue to be small. 146 refs., 5 figs., 11 tabs

Unresolved issues for the disposal of remote-handled transuranic waste in the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

Silva, M.K.; Neill, R.H.

1994-09-01

The purpose of the Waste Isolation Pilot Plant (WIPP) is to dispose of 176,000 cubic meters of transuranic (TRU) waste generated by the defense activities of the US Government. The envisioned inventory contains approximately 6 million cubic feet of contact-handled transuranic (CH TRU) waste and 250,000 cubic feet of remote handled transuranic (RH TRU) waste. CH TRU emits less than 0.2 rem/hr at the container surface. Of the 250,000 cubic feet of RH TRU waste, 5% by volume can emit up to 1,000 rem/hr at the container surface. The remainder of RH TRU waste must emit less than 100 rem/hr. These are major unresolved problems with the intended disposal of RH TRU waste in the WIPP. (1) The WIPP design requires the canisters of RH TRU waste to be emplaced in the walls (ribs) of each repository room. Each room will then be filled with drums of CH TRU waste. However, the RH TRU waste will not be available for shipment and disposal until after several rooms have already been filled with drums of CH TRU waste. RH TRU disposal capacity will be loss for each room that is first filled with CH TRU waste. (2) Complete RH TRU waste characterization data will not be available for performance assessment because the facilities needed for waste handling, waste treatment, waste packaging, and waste characterization do not yet exist. (3) The DOE does not have a transportation cask for RH TRU waste certified by the US Nuclear Regulatory Commission (NRC). These issues are discussed along with possible solutions and consequences from these solutions. 46 refs

Prioritization of generic safety issues

International Nuclear Information System (INIS)

Emrit, R.; Minners, W.; VanderMolen, H.

1983-12-01

This report presents the priority rankings for generic safety issues related to nuclear power plants. The purpose of these rankings is to assist in the timely and efficient allocation of NRC resources for the resolution of those safety issues that have a significant potential for reducing risk. The report focuses on the prioritization of generic safety issues. Issues primarily concerned with the licensing process or environmental protection and not directly related to safety have been excluded from prioritization. The prioritized issues include: TMI Action Plan items under development; previously proposed issues covered by Task Action Plans, except issues designated at Unresolved Safety Issues (USIs) which had already been assigned high priority; and newly-proposed issues. Future supplements to this report will include the prioritization of additional issues. The safety priority rankings are HIGH, MEDIUM, LOW, and DROP and have been assigned on the basis of risk significance estimates, the ratio of risk to costs and other impacts estimated to result if resolutions of the safety issues were implemented, and the consideration of uncertainties and other quantitative or qualitative factors. To the extent practical, estimates are quantitative

URR-PACK: Calculating Self-Shielding in the Unresolved Resonance Energy Range

International Nuclear Information System (INIS)

Cullen, Dermott E.; Trkov, Andrej

2016-07-01

This report describes HOW to calculate self-shielding in the unresolved resonance region (URR), in terms of the computer codes we provide to allow a user to do these calculations himself. Here we only describe HOW to calculate; a longer companion report describes in detail WHY it is necessary to include URR self-shielding.

Final disposal of spent nuclear fuel in Sweden. Some unresolved issues and challenges in the design and implementation of the forthcoming planning and EIA processes

International Nuclear Information System (INIS)

Bjarnadottir, H.; Hilding-Rydevik, T.

2001-06-01

The aim of the study is to highlight some unresolved and challenging issues in the forthcoming approximately six year long Environmental Impact Assessment (EIA) and planning process of the long-term disposal of spent nuclear fuel in Sweden. Different international and Nordic experiences of the processes for final disposal as well as from other development of similar scope, where experiences assumed to be of importance for final disposal of nuclear waste, have been described. Furthermore, issues relating to 'good EIA practice' as well as certain aspects of planning theory have also been presented. The current Swedish situation for the planning and EIA process of the final disposal of spent nuclear fuel was also been summarized. These different 'knowledge areas' have been compared and measured against our perception of the expectations towards the forthcoming process, put forward by different Swedish actors in the field. The result is a presentation of a number of questions and identification issues that the authors consider need special attention in the design and conduction of the planning and EIA process. The study has been realized through a literature survey and followed by reading and analysis of the written material. The main focus of the literature search was on material describing planning processes, actor perspectives and EIA. Material and literature on the technical and scientific aspects of spent nuclear fuel disposal was however deliberately avoided. There is a wealth of international and Swedish literature concerning final disposal of spent nuclear fuel - concerning both technical issues and issues concerning for example public participation and risk perception. But material of a more systematic and comparative nature (relating to both empirical and theoretical issues, and to practical experiences) in relation to EIA processes and communicative planning for final disposal of spent nuclear fuel seems to be more sparsely represented. Our perception of

A prioritization of generic safety issues

International Nuclear Information System (INIS)

Emrit, R.; Riggs, R.; Milstead, W.; Pittman, J.

1991-07-01

This report presents the priority rankings for generic safety issues and related to nuclear power plants. The purpose of these rankings is to assist in the timely and efficient allocation of NRC resources for the resolution of those safety issues that have a significant potential for reducing risk. The report focuses on the prioritization of generic safety issues. Issues primarily concerned with the licensing process or environmental protection and not directly related to safety have been excluded from prioritization. The prioritized issues include: TMI Action Plan items under development; previously proposed issues covered by Task Action Plans, except issues designated as Un-resolved Safety Issues (USIs) which had already been assigned high priority; and newly-proposed issues. Future supplements to this report will include the prioritization of additional issues. The safety priority rankings are High, Medium, Low, and Drop and have been assigned on the basis of risk significance estimates, the ratio of risk to costs and other impacts estimated to result if resolutions of the safety issues were implemented, and the consideration of uncertainties and other quantitative or qualitative factors. To the extent practical, estimates are quantitative. 1310 refs

Can temporal fine structure represent the fundamental frequency of unresolved harmonics?

Science.gov (United States)

Oxenham, Andrew J; Micheyl, Christophe; Keebler, Michael V

2009-04-01

At least two modes of pitch perception exist: in one, the fundamental frequency (F0) of harmonic complex tones is estimated using the temporal fine structure (TFS) of individual low-order resolved harmonics; in the other, F0 is derived from the temporal envelope of high-order unresolved harmonics that interact in the auditory periphery. Pitch is typically more accurate in the former than in the latter mode. Another possibility is that pitch can sometimes be coded via the TFS from unresolved harmonics. A recent study supporting this third possibility [Moore et al. (2006a). J. Acoust. Soc. Am. 119, 480-490] based its conclusion on a condition where phase interaction effects (implying unresolved harmonics) accompanied accurate F0 discrimination (implying TFS processing). The present study tests whether these results were influenced by audible distortion products. Experiment 1 replicated the original results, obtained using a low-level background noise. However, experiments 2-4 found no evidence for the use of TFS cues with unresolved harmonics when the background noise level was raised, or the stimulus level was lowered, to render distortion inaudible. Experiment 5 measured the presence and phase dependence of audible distortion products. The results provide no evidence that TFS cues are used to code the F0 of unresolved harmonics.

A Structural Approach to Unresolved Mourning in Single Parent Family Systems.

Science.gov (United States)

Fulmer, Richard H.

1983-01-01

Considers the mother's depression as a special problem in therapy of single-parent families, resulting from unresolved mourning maintained by the family system. Offers reasons why the single-parent family's structure seems inherently vulnerable to unresolved mourning. Suggests techniques of Structural Family Therapy to facilitate mourning in such…

Unresolved trauma in mothers: intergenerational effects and the role of reorganization

Science.gov (United States)

Iyengar, Udita; Kim, Sohye; Martinez, Sheila; Fonagy, Peter; Strathearn, Lane

2014-01-01

A mother's unresolved trauma may interfere with her ability to sensitively respond to her infant, thus affecting the development of attachment in her own child, and potentially contributing to the intergenerational transmission of trauma. One novel construct within the Dynamic Maturational Model of Attachment and Adaptation (DMM) coding of the Adult Attachment Interview (AAI) is “reorganization,” a process whereby speakers are actively changing their understanding of past and present experiences and moving toward attachment security. We conducted a study of mothers with unresolved trauma, exploring their own attachment classification, attachment outcomes of their children, and the potential effects of reorganization on child attachment. Forty-seven first-time mothers participated in the AAI during pregnancy, and returned with their child at 11 months to assess child attachment using the Strange Situation Procedure. Mothers with and without unresolved trauma were compared. We found that mothers with unresolved trauma had insecure attachment themselves and were more likely to have infants with insecure attachment. However, the one exception was that all of the mothers with unresolved trauma who were reorganizing toward secure attachment had infants with secure attachment. These preliminary findings suggest that mothers who are reorganizing may be able to more sensitively respond to their child's cues, contributing to the development of secure attachment. While our results need to be replicated in a larger cohort, this study is the first to explore the construct of reorganization and its potential relationship with child attachment. If confirmed in future studies, it may provide clinical insight into the intergenerational transmission of insecure attachment within the context of unresolved trauma. PMID:25225490

Emotion theory and research: highlights, unanswered questions, and emerging issues.

Science.gov (United States)

Izard, Carroll E

2009-01-01

Emotion feeling is a phase of neurobiological activity, the key component of emotions and emotion-cognition interactions. Emotion schemas, the most frequently occurring emotion experiences, are dynamic emotion-cognition interactions that may consist of momentary/situational responding or enduring traits of personality that emerge over developmental time. Emotions play a critical role in the evolution of consciousness and the operations of all mental processes. Types of emotion relate differentially to types or levels of consciousness. Unbridled imagination and the ability for sympathetic regulation of empathy may represent both potential gains and losses from the evolution and ontogeny of emotion processes and consciousness. Unresolved issues include psychology's neglect of levels of consciousness that are distinct from access or reflective consciousness and use of the term "unconscious mind" as a dumpster for all mental processes that are considered unreportable. The relation of memes and the mirror neuron system to empathy, sympathy, and cultural influences on the development of socioemotional skills are unresolved issues destined to attract future research.

Materials and design bases issues in ASME Code Case N-47

International Nuclear Information System (INIS)

Huddleston, R.L.; Swindeman, R.W.

1993-04-01

A preliminary evaluation of the design bases (principally ASME Code Case N-47) was conducted for design and operation of reactors at elevated temperatures where the time-dependent effects of creep, creep-fatigue, and creep ratcheting are significant. Areas where Code rules or regulatory guides may be lacking or inadequate to ensure the operation over the expected life cycles for the next-generation advanced high-temperature reactor systems, with designs to be certified by the US Nuclear Regulatory Commission, have been identified as unresolved issues. Twenty-two unresolved issues were identified and brief scoping plans developed for resolving these issues

A Review: Passive System Reliability Analysis – Accomplishments and Unresolved Issues

Energy Technology Data Exchange (ETDEWEB)

Nayak, Arun Kumar, E-mail: arunths@barc.gov.in [Reactor Engineering Division, Reactor Design and Development Group, Bhabha Atomic Research Centre, Mumbai (India); Chandrakar, Amit [Homi Bhabha National Institute, Mumbai (India); Vinod, Gopika [Reactor Safety Division, Reactor Design and Development Group, Bhabha Atomic Research Centre, Mumbai (India)

2014-10-10

Reliability assessment of passive safety systems is one of the important issues, since safety of advanced nuclear reactors rely on several passive features. In this context, a few methodologies such as reliability evaluation of passive safety system (REPAS), reliability methods for passive safety functions (RMPS), and analysis of passive systems reliability (APSRA) have been developed in the past. These methodologies have been used to assess reliability of various passive safety systems. While these methodologies have certain features in common, but they differ in considering certain issues; for example, treatment of model uncertainties, deviation of geometric, and process parameters from their nominal values. This paper presents the state of the art on passive system reliability assessment methodologies, the accomplishments, and remaining issues. In this review, three critical issues pertaining to passive systems performance and reliability have been identified. The first issue is applicability of best estimate codes and model uncertainty. The best estimate codes based phenomenological simulations of natural convection passive systems could have significant amount of uncertainties, these uncertainties must be incorporated in appropriate manner in the performance and reliability analysis of such systems. The second issue is the treatment of dynamic failure characteristics of components of passive systems. REPAS, RMPS, and APSRA methodologies do not consider dynamic failures of components or process, which may have strong influence on the failure of passive systems. The influence of dynamic failure characteristics of components on system failure probability is presented with the help of a dynamic reliability methodology based on Monte Carlo simulation. The analysis of a benchmark problem of Hold-up tank shows the error in failure probability estimation by not considering the dynamism of components. It is thus suggested that dynamic reliability methodologies must be

Thyrotropin receptor mutations and thyroid hyperfunctioning adenomas ten years after their first discovery: unresolved questions.

Science.gov (United States)

Arturi, F; Scarpelli, D; Coco, A; Sacco, R; Bruno, R; Filetti, S; Russo, D

2003-04-01

Ten years after the first description of activating mutations in the thyroid stimulating hormone receptor (TSHR) gene in sporadic autonomous hyperfunctioning thyroid adenomas, there is general agreement in assigning a major pathogenic role of this genetic abnormality, acting via the constitutive activation of the cAMP pathway, in both the growth and functional characteristic of these tumours. From the beginning, however, the pathophysiological and clinical relevance of somatic TSHR mutations has been debated and some arguments still exist against a fully causative role of these mutations and the practical value of detecting these mutations for the diagnosis, treatment and prognosis of thyroid hot nodules. Some major issues will be examined herein, including (a) the frequency of TSHR alterations in various reports showing that the genetic abnormality underlying the pathogenesis of a substantial subset of thyroid tumours has yet to be identified; (b) the limitations of the present experimental models, which suggest greater caution in the interpretation of in vitro results; (c) the still unresolved question of absence of genotype-phenotype correlation. Clarification of these issues may hopefully provide new and useful tools for improving the clinical management of this disease.

Social Capital in Organizations - Perspectives and Unresolved Issues

DEFF Research Database (Denmark)

Waldstrøm, Christian

a consistent, bridging theory. Finally, there is a lack of understanding on how social capital develops over time and the potential benefits of taking a life-cycle view of social capital. In conclusion, the field of social capital in organizations still needs a consistent and coordinated research effort......The importance and usefulness of social capital as a concept in the study of organizations have been established by a large body of research. The aim of this paper is to review the concept of social capital in an organizational context, and identifying five main issues that need to be addressed....... Secondly, it is necessary to determine whether social capital can or should be measured. Thirdly, the negative aspects of social capital should be explored and integrated into the existing research. Fourthly, the field between social capital of the individual and organizational social capital lacks...

A Short History of ENDF/B Unresolved Resonance Parameters

Energy Technology Data Exchange (ETDEWEB)

Cullen, Dermott E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2010-10-31

This paper is designed to address two topics relating to ENDF/B data in the unresolved resonance region, Part 1: For years code users have pointed out and complained that various ENDF data processing codes, in particular PREPRO and NJOY, produce different answers from one another for the cross sections in unresolved resonance region. First I assure code users that NJOY has now been updated to agree with PREPRO, so that this problem has now been solved. Part 2: Next, this paper documents why we saw these differences; the emphasis here is on explaining what my own codes do, but I will also try to briefly outline what other codes do, so the reader can understand why we were producing different answers. The first topic should be of general interest to all readers, particularly users of our codes, whereas the second topic will be of more limited interest only to those readers who are interested in the details of our calculations in the unresolved resonance region. Now that our PREPRO and NJOY results agree we consider this problem solved and no further action is necessary.

Interactions among resonances in the unresolved region

International Nuclear Information System (INIS)

Queiroz Bogado Leite, S. de.

1982-11-01

The theory on resonance absorption in the unresolved region is reviewed and a subroutine is presented, optional to UNRES in MC 2 code. Comparisons with the isolated resonance model suggest the necessity, in some cases, of considering interference and overlapping effects among resonances of the system. (Author) [pt

Impact of MCNP unresolved resonance probability-table treatment on uranium and plutonium benchmarks

International Nuclear Information System (INIS)

Mosteller, R.D.; Little, R.C.

1998-01-01

Versions of MCNP up through and including 4B have not accurately modeled neutron self-shielding effects in the unresolved resonance energy region. Recently, a probability-table treatment has been incorporated into a developmental version of MCNP. This paper presents MCNP results for a variety of uranium and plutonium critical benchmarks, calculated with and without the probability-table treatment

Biodiversity and systematics in cephalopods: Unresolved problems ...

African Journals Online (AJOL)

Some problems of cephalopod biodiversity are discussed. Many squid species are represented by 2–4 intraspecies groupings that may be wholly or partly sympatric, but differ in spawning season and size at maturity. They may be genetically distinct stock units, but their taxonomic status remains unresolved. Discovery of a ...

Eating disorders in adolescence: attachment issues from a developmental perspective

Directory of Open Access Journals (Sweden)

Manuela eGander

2015-08-01

Full Text Available In the present article we review findings from an emerging body of research on attachment issues in adolescents with eating disorders from a developmental perspective. First, we will outline the crucial developmental changes in the attachment system and discuss how they might be related to the early onset of the disease. Then we will report on the major results from attachment studies using self-report and narrative instruments in that age group. Studies with a developmental approach on attachment will be analyzed in more detail. The high incidence of the unresolved attachment pattern in eating disorder samples is striking, especially for patients with anorexia nervosa. Interestingly, this predominance of the unresolved category was also found in their mothers. To date, these transgenerational aspects are still poorly understood and therefore represent an exciting research frontier. Future studies that include larger adolescent samples and provide a more detailed description including symptom severity and comorbidity would contribute to a better understanding of this complex and painful condition.

Stochasticity effects on derivation of physical parameters of unresolved star clusters

OpenAIRE

de Meulenaer, Philippe; Narbutis, Donatas; Mineikis, Tadas; Vansevičius, Vladas

2013-01-01

We developed a method for a fast modeling of broad-band UBVRI integrated magnitudes of unresolved star clusters and used it to derive their physical parameters (age, mass, and extinction). The method was applied on M33 galaxy cluster sample and consistency of ages and masses derived from unresolved observations with the values derived from resolved stellar photometry was demonstrated. We found that interstellar extinction causes minor age-extinction degeneracy for the studied sample due to a ...

Major unresolved issues preventing a timely resolution to radioactive waste disposal

International Nuclear Information System (INIS)

1978-01-01

GAO surveyed a portion of the literature on radioactive waste management and identified those major issues which could impede the timely and comprehensive removal of obstacles to demonstrating a national radioactive waste disposal program. Presently, U.S. radioactive waste policy goals are unclear in that there is no clear differentiation of management, regulation (licensing), and research, development, and demonstration functions. Decisions on such important issues as regulatory responsibility over radioactive wastes, criteria for radioactive waste form and performance, method of final disposition, and repository site locations must be made, and made soon, in order to assure public health and safety and adequate management of these potentially hazardous materials

The Nature of the Unresolved Extragalactic Cosmic Soft X-Ray Background

Science.gov (United States)

Cappelluti, N.; Ranalli, P.; Roncarelli, M.; Arevalo, P.; Zamorani, G.; Comastri, A.; Gilli, R.; Rovilos, E.; Vignali, C.; Allevato, V.;

Final disposal of spent nuclear fuel in Sweden. Some unresolved issues and challenges in the design and implementation of the forthcoming planning and EIA processes

Energy Technology Data Exchange (ETDEWEB)

Bjarnadottir, H.; Hilding-Rydevik, T. [Nordregio, Stockholm (Sweden)

2001-06-01

The aim of the study is to highlight some unresolved and challenging issues in the forthcoming approximately six year long Environmental Impact Assessment (EIA) and planning process of the long-term disposal of spent nuclear fuel in Sweden. Different international and Nordic experiences of the processes for final disposal as well as from other development of similar scope, where experiences assumed to be of importance for final disposal of nuclear waste, have been described. Furthermore, issues relating to 'good EIA practice' as well as certain aspects of planning theory have also been presented. The current Swedish situation for the planning and EIA process of the final disposal of spent nuclear fuel was also been summarized. These different 'knowledge areas' have been compared and measured against our perception of the expectations towards the forthcoming process, put forward by different Swedish actors in the field. The result is a presentation of a number of questions and identification issues that the authors consider need special attention in the design and conduction of the planning and EIA process. The study has been realized through a literature survey and followed by reading and analysis of the written material. The main focus of the literature search was on material describing planning processes, actor perspectives and EIA. Material and literature on the technical and scientific aspects of spent nuclear fuel disposal was however deliberately avoided. There is a wealth of international and Swedish literature concerning final disposal of spent nuclear fuel - concerning both technical issues and issues concerning for example public participation and risk perception. But material of a more systematic and comparative nature (relating to both empirical and theoretical issues, and to practical experiences) in relation to EIA processes and communicative planning for final disposal of spent nuclear fuel seems to be more sparsely represented

On the use of risk-informed regulation including organizational factors

International Nuclear Information System (INIS)

Gibelli, S.M.O.; Alvarenga, M.A.B.

1998-01-01

Risk-Informed Regulation (RIR) can be applied by using Probabilistic Safety Assessment (PSA) as a basic tool. Traditionally, PSA methodology encompasses the calculation of failure probabilities of Structures, Systems and Components (SSCs) and direct associated human errors. However, there are indirect causes related to human failures, associated with Organizational Factors, which are normally not included in fault trees, that may influence plant risk evaluation. This paper discusses on possible applications of RIR and on Organizational Factors. It also presents a classification of Angra-1 NPP unresolved issues, aiming a future inclusion of these factors into a PSA calculation. (author)

Assessment method to predict the rate of unresolved false alarms

International Nuclear Information System (INIS)

Reardon, P.T.; Eggers, R.F.; Heaberlin, S.W.

1982-06-01

A method has been developed to predict the rate of unresolved false alarms of material loss in a nuclear facility. The computer program DETRES-1 was developed. The program first assigns the true values of control unit components receipts, shipments, beginning and ending inventories. A normal random number generator is used to generate measured values of each component. A loss estimator is calculated from the control unit's measured values. If the loss estimator triggers a detection alarm, a response is simulated. The response simulation is divided into two phases. The first phase is to simulate remeasurement of the components of the detection loss estimator using the same or better measurement methods or inferences from surrounding control units. If this phase of response continues to indicate a material loss, phase of response simulating a production shutdown and comprehensive cleanout is initiated. A new loss estimator is found, and tested against the alarm thresholds. If the estimator value is below the threshold, the original detection alarm is considered resolved; if above the threshold, an unresolved alarm has occurred. A tally is kept of valid alarms, unresolved false alarms, and failure to alarm upon a true loss

Perception of the pitch of unresolved harmonics by 3- and 7-month-old human infants.

Science.gov (United States)

Lau, Bonnie K; Werner, Lynne A

2014-08-01

Three-month-olds discriminate resolved harmonic complexes on the basis of missing fundamental (MF) pitch. In view of reported difficulty in discriminating unresolved complexes at 7 months and striking changes in the organization of the auditory system during early infancy, infants' ability to discriminate unresolved complexes is of some interest. This study investigated the ability of 3-month-olds, 7-month-olds, and adults to discriminate the pitch of unresolved harmonic complexes using an observer-based method. Stimuli were MF complexes bandpass filtered with a -12 dB/octave slope, combined in random phase, presented at 70 dB sound pressure level (SPL) for 650 ms with a 50 ms rise/fall with a pink noise at 65 dB SPL. The conditions were (1) "LOW" unresolved harmonics (2500-4500 Hz) based on MFs of 160 and 200 Hz and (2) "HIGH" unresolved harmonics (4000-6000 Hz) based on MFs of 190 and 200 Hz. To demonstrate MF discrimination, participants had to ignore spectral changes in complexes with the same fundamental and respond only when the fundamental changed. Nearly all infants tested categorized complexes by MF pitch suggesting discrimination of pitch extracted from unresolved harmonics by 3 months. Adults also categorized the complexes by MF pitch, although musically trained adults were more successful than musically untrained adults.

Technical issues for WIPP

International Nuclear Information System (INIS)

Hunter, T.O.

1979-01-01

Emplacement of wastes in the WIPP will include experiments on various waste types which will provide essential data on waste-rock interaction and repository response. These experiments will include evolution of the synergistic effects of both heat production, radiation, and actual waste forms. While these studies will provide essential data on the validity of waste isolation in bedded salt, they will be preceded by a broad-based experimental program which will resolve many of the current technical issues providing not only an assessment of the safety of performing such experiments but also the technical basis for assurance that the appropriate experiments are performed. Data and predictive modeling techniques, which are currently available, can bound the consequences associated with these technical issues. Predictions of the impact on public safety based on these analyses indicate that safe waste disposal in WIPP salt beds is achievable; however, a major use of WIPP will be to conduct realistic experiments with HLW forms to address some of the unresolved details of these waste/salt interactions

Efficacy of Artemether in Unresolving Plasmodium Falciparum Malaria

African Journals Online (AJOL)

The emergence of possible resistant Plasmodium falciparum malaria to artemisinin known for its immense benefit in malaria chemotherapy is worrisome. We report a case of unresolving Plasmodium falciparum malaria to Artesunate treatment in a 29- year old man in Enugu Nigeria. Plasmodium falciparum count of Giemsa ...

The American Indian Holocaust: Healing Historical Unresolved Grief.

Science.gov (United States)

Brave Heart, Maria Yellow Horse; DeBruyn, Lemyra M.

1998-01-01

Argues for the existence of historical unresolved grief among American Indians. Outlines the historical legacy of war, genocide, and boarding schools resulting in intergenerational trauma and a host of associated social problems. Suggests healing strategies that integrate modern and traditional approaches to healing at the individual, family, and…

Unresolved resonance range cross section, probability tables and self shielding factor

International Nuclear Information System (INIS)

Sublet, J.Ch.; Blomquist, R.N.; Goluoglu, S.; Mac Farlane, R.E.

2009-07-01

The performance and methodology of 4 processing codes have been compared in the unresolved resonance range of a selected set of isotopes. Those isotopes have been chosen to encompass most cases encountered in the unresolved energy range contained in major libraries like Endf/B-7 or Jeff-3.1.1. The code results comparison is accompanied by data format and formalism examinations and processing code fine-interpretation study. After some improvements, the results showed generally good agreement, although not perfect with infinite dilute cross-sections. However, much larger differences occur when shelf-shielded effective cross-sections are compared. The infinitely dilute cross-section are often plot checked but it is the probability table derived and shelf-shielded cross sections that are used and interpreted in criticality and transport calculations. This suggests that the current evaluation data format and formalism, in the unresolved resonance range should be tightened up, ambiguities removed. In addition production of the shelf shielded cross-sections should be converged to a much greater accuracy. (author)

Regulatory and institutional issues for development of remedial action strategies at ORNL

International Nuclear Information System (INIS)

Kocher, D.C.

1988-01-01

This paper discusses a number of unresolved regulatory and institutional issues of fundamental importance to the development of strategies for cleanup of sites contaminated by the radioactive materials at Oak Ridge National Laboratory. These issues include the development of criteria for limiting radiation exposures of the public from remedial action sites, the time period to be assumed for active institutional controls over contaminated sites and the location at which such controls will be maintained, and the applicability of current standards for radioactivity in drinking water to surface waters and ground waters on the Oak Ridge Reservation. Proposals for resolution of these issues emphasize the need to protect public health, but in a cost-effective manner. 21 refs

Unresolved pain in children: a relational ethics perspective.

Science.gov (United States)

Olmstead, Deborah L; Scott, Shannon D; Austin, Wendy J

2010-11-01

It is considered the right of children to have their pain managed effectively. Yet, despite extensive research findings, policy guidelines and practice standard recommendations for the optimal management of paediatric pain, clinical practices remain inadequate. Empirical evidence definitively shows that unrelieved pain in children has only harmful consequences, with no benefits. Contributing factors identified in this undermanaged pain include the significant role of nurses. Nursing attitudes and beliefs about children's pain experiences, the relationships nurses share with children who are suffering, and knowledge deficits in pain management practices are all shown to impact unresolved pain in children. In this article, a relational ethics perspective is used to explore the need for nurses to engage in authentic relationships with children who are experiencing pain, and to use evidence-based practices to manage that pain in order for this indefensible suffering of children to end.

Characterisation of unresolved complex mixtures of hydrocarbons

OpenAIRE

Gough, Mark Adrian

1989-01-01

Metadata merged with duplicate record (http://hdl.handle.net/10026.1/666) on 20.12.2016 by CS (TIS). This is a digitised version of a thesis that was deposited in the University Library. If you are the author please contact PEARL Admin () to discuss options. The hydrocarbons of Recent Polluted.., sediments, in-reservoir and laboratory biodegraded crude oils, and certain petroleum products (e. g. lubricating oils) often display "humps" or Unresolved Complex...

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

OpenAIRE

Hu, H.; Haas, S.A.; Chelly, J.; Van Esch, H.; Raynaud, M.; de Brouwer, A.P.M.; Weinert, S.; Froyen, G.; Frints, S.G.M.; Laumonnier, F.; Zemojtel, T.; Love, M.I.; Richard, H.; Emde, A.K.; Bienek, M.

2016-01-01

X-linked intellectual disability (XLID) is a clinically and genetically heterogeneous disorder. During the past two decades in excess of 100 X-chromosome ID genes have been identified. Yet, a large number of families mapping to the X-chromosome remained unresolved suggesting that more XLID genes or loci are yet to be identified. Here, we have investigated 405 unresolved families with XLID. We employed massively parallel sequencing of all X-chromosome exons in the index males. The majority of ...

Ethics issues in retrievability

International Nuclear Information System (INIS)

Jensen, M.; Larsson, C.M.; Norden, M.

2000-01-01

We can isolate some issues, which should not be unresolved for a longer period of time. Disputes over well-defined waste management options fall in this category. The concept of retrievability has a possibility to invoke a series of questions in the minds of both specialists and non-specialists. It is intrinsically vague, in that it may refer to different phases in the repository's life, and to both open and closed repositories in the long time frame. Requirements for retrievability opens a series of issues, including open-ended philosophical question, which may give the impressions that things are not properly taken care of, since the experts differ in opinion. If such disputes cannot be resolved by consulting the existing legal framework, efforts should be made to put them to trial in the proper forum, i.e. parliament and national or local government or authorities, depending on the problem. In contrast, the value of institutional controls can easily be seen as an ethical value, whether included in the regulation of not. It has the potential to deter human intrusion and to allow remedial action by carrying information about a repository. (author)

Spatially unresolved SED fitting can underestimate galaxy masses: a solution to the missing mass problem

Science.gov (United States)

Sorba, Robert; Sawicki, Marcin

2018-05-01

We perform spatially resolved, pixel-by-pixel Spectral Energy Distribution (SED) fitting on galaxies up to z ˜ 2.5 in the Hubble eXtreme Deep Field (XDF). Comparing stellar mass estimates from spatially resolved and spatially unresolved photometry we find that unresolved masses can be systematically underestimated by factors of up to 5. The ratio of the unresolved to resolved mass measurement depends on the galaxy's specific star formation rate (sSFR): at low sSFRs the bias is small, but above sSFR ˜ 10-9.5 yr-1 the discrepancy increases rapidly such that galaxies with sSFRs ˜ 10-8 yr-1 have unresolved mass estimates of only one-half to one-fifth of the resolved value. This result indicates that stellar masses estimated from spatially unresolved data sets need to be systematically corrected, in some cases by large amounts, and we provide an analytic prescription for applying this correction. We show that correcting stellar mass measurements for this bias changes the normalization and slope of the star-forming main sequence and reduces its intrinsic width; most dramatically, correcting for the mass bias increases the stellar mass density of the Universe at high redshift and can resolve the long-standing discrepancy between the directly measured cosmic SFR density at z ≳ 1 and that inferred from stellar mass densities (`the missing mass problem').

Androgyny as Trait and as Role: Unresolved Issues.

Science.gov (United States)

Spence, Janet T.

In the late 1970's androgyny as a concept gained respectability, accompanied, however, by a backlash. Debate centered primarily on scientific grounds and both sides failed to define the concepts of masculinity, femininity and androgyny, including possible cultural relativity. Most empirical research on androgyny uses either the BSRI or the PAQ…

Neutron cross sections in the unresolved resonance region

International Nuclear Information System (INIS)

Janeva, N.; Lukyanov, A.; Koyumdjieva, N.; Volev, K.

2005-01-01

In this work a development of the characteristic function model, created to reveal the resonance cross section structure in the unresolved resonance region is presented. The main advantage of this model is the calculation of resonance averaged self-shielding factors analytically. To determine average values of the cross sections and their functionals the function of joint statistical distribution of the R-matrix real and imaginary parts should be used. The characteristic function of such distribution is determined and the resonance ladder for the unresolved region is optimized to calculate the group averaged functionals in the same way as it is in the resolved resonance region. The main advantage of this model is the calculation of resonance averaged self-shielding factors analytically. The neutron width energy dependence leads to some deformation in the shape of resonances. This deformation is most apparent near the inelastic scattering threshold. For the case when the inelastic channel momentum is zero we present the formula for level shape bellow and over the inelastic threshold and the calculated resonance deformation in dependence of the position of the resonance in respect to the threshold. (authors)

Unresolved Subclinical Hypothyroidism is Independently Associated with Progression of Chronic Kidney Disease

Science.gov (United States)

Kim, Eun Oh; Lee, Ihn Suk; Choi, Yoo A; Lee, Sang Ju; Chang, Yoon Kyung; Yoon, Hye Eun; Jang, Yi Sun; Lee, Jong Min; Kim, Hye Soo; Yang, Chul Woo; Kim, Suk Young; Hwang, Hyeon Seok

2014-01-01

Background and Aim: Patients with chronic kidney disease (CKD) often have subclinical hypothyroidism. However, few reports have investigated changes in the status of subclinical hypothyroidism in CKD patients and its clinical significance in CKD progression. Methods: We included 168 patients with nondialysis-dependent CKD stages 2-4. The normalization of subclinical hypothyroidism during follow-up was assessed, and the association between transitions in subclinical hypothyroid status and the rate of decline of the estimated glomerular filtration rate (eGFR) was investigated. Results: At baseline, 127 patients were euthyroid and 41 (24.4%) patients were diagnosed with subclinical hypothyroidism. Of these 41 patients, 21 (51.2%) spontaneously resolved to euthyroid during follow-up. The rate of eGFR decline of patients with resolved subclinical hypothyroidism was similar to that of euthyroid patients. The patients with unresolved subclinical hypothyroidism showed a steeper renal function decline than patients with euthyroidism or resolved subclinical hypothyroidism (all p hypothyroidism than in those who were euthyroid (p = 0.006). In multivariate linear regression for rate of eGFR decrease, unresolved subclinical hypothyroidism (β = -5.77, p = 0.001), baseline renal function (β = -0.12, p hypothyroidism did not resolve to euthyroidism, and this lack of resolution was independently associated with rapid renal function decline. PMID:24396286

Status of safety issues at licensed power plants

International Nuclear Information System (INIS)

1991-05-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, a program has been established whereby an annual NUREG report will be published on the status of licensee implementation and NRC verification of safety issues in major NRC requirement areas. This report, the second volume of a three-volume series, addresses the status of unresolved safety issues (USIs) at licensed plants. The data contained in these NUREG reports are a product of the NRC's Safety Issues Management System (SIMS) database, which is maintained by the Project Management Staff in the Office of Nuclear Reactor Regulation and by NRC regional personnel. The purpose of this report is to provide a comprehensive description of the status of implementation and verification of the 27 safety issues designated as USIs and to make this information available to other interested parties, including the public. A corollary purpose of this NUREG report is to serve as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues up until requirements are approved for imposition at licensed plants. 3 figs., 4 tabs

Congenital Adrenal Hyperplasia: Unresolved Issues.

Science.gov (United States)

Yau, Mabel; Khattab, Ahmed; Poppas, Dix; Ghizzoni, Lucia; New, Maria

2016-01-01

Congenital adrenal hyperplasia (CAH) describes a family of disorders that comes from enzymatic deficiencies in cortisol production, with 21-hydroxylase deficiency causing ∼90% of cases. Distinction is made between the severe classical form and milder nonclassical form of CAH. Molecular genetic analysis is used to confirm the hormonal diagnosis. A high rate of genotype-phenotype disconcordance has been found in 21-hydroxylase deficiency. The goal of treatment is to replace with synthetic glucocorticoids and mineralocorticoids and suppress adrenal androgen production. The treatment of patients affected with nonclassical CAH, particularly males, remains controversial. Variable synthetic glucocorticoids are used and new modes of glucocorticoid delivery are under investigation. To improve height, growth hormone and other adjuvant therapies are employed. Long-term outcomes of genital surgery using modern techniques in females affected with classical CAH continue to be investigated. Prenatal treatment with dexamethasone is available to avoid ambiguous genitalia in these females. Although studies have shown its safety to mother and fetus, prenatal treatment is still regarded as experimental. Currently, prenatal diagnosis of CAH can only be obtained through invasive methods. Recently, the detection of cell-free fetal DNA in maternal plasma has made it possible to make this diagnosis earlier and noninvasively. © 2016 S. Karger AG, Basel.

Representation of the neutron cross sections in the unresolved resonance region

International Nuclear Information System (INIS)

de Saussure, G.; Perez, R.B.

1975-01-01

Some limitations of the statistical approach to the representation of cross sections in the unresolved region are discussed and it is suggested that the actual Doppler-broadened cross sections should be used instead. 5 figures

Effects of cochlear compression and frequency selectivity on pitch discrimination of complex tones with unresolved harmonics

DEFF Research Database (Denmark)

Bianchi, Federica; Fereczkowski, Michal; Zaar, Johannes

2015-01-01

Physiological studies have shown that noise-induced sensorineural hearing loss (SNHL) enhances the amplitude of envelope coding in auditory-nerve fibers. As pitch coding of unresolved complex tones is assumed to rely on temporal envelope coding mechanisms, this study investigated...... for the RP condition. Overall, these findings suggest that both reduced cochlear compression and auditory filter broadening alter the envelope representation of unresolved complex tones, leading to changes in pitch-discrimination performance....... pitchdiscrimination performance in listeners with SNHL. Pitch-discrimination thresholds were obtained in 14 normal-hearing (NH) and 10 hearingimpaired (HI) listeners for sine-phase (SP) and random-phase (RP) unresolved complex tones. The HI listeners performed, on average, similarly as the NH listeners in the SP...

Guaranteed Unresolved Point Source Emission and the Gamma-ray Background

International Nuclear Information System (INIS)

Pavlidou, Vasiliki; Siegal-Gaskins, Jennifer M.; Brown, Carolyn; Fields, Brian D.; Olinto, Angela V.

2007-01-01

The large majority of EGRET point sources remain without an identified low-energy counterpart, and a large fraction of these sources are most likely extragalactic. Whatever the nature of the extragalactic EGRET unidentified sources, faint unresolved objects of the same class must have a contribution to the diffuse extragalactic gamma-ray background (EGRB). Understanding this component of the EGRB, along with other guaranteed contributions from known sources (blazars and normal galaxies), is essential if we are to use this emission to constrain exotic high-energy physics. Here, we follow an empirical approach to estimate whether the contribution of unresolved unidentified sources to the EGRB is likely to be important. Additionally, we discuss how upcoming GLAST observations of EGRET unidentified sources, their fainter counterparts, and the Galactic and extragalactic diffuse backgrounds, will shed light on the nature of the EGRET unidentified sources even without any positional association of such sources with low-energy counterparts

Outstanding environmental issues. A review of the EU's environmental agenda

NARCIS (Netherlands)

Netherlands Environmental Assessment Agency =; Netherlands Environmental; European Environmental Agency EEA

2004-01-01

EU environmental policy has led to economic investments that have clearly benefited the health of people and ecosystems. But there are still important unresolved environmental issues in Europe, in particular climate change, loss of biodiversity and air pollution in urban areas. Appropriate

37 CFR 1.18 - Patent post allowance (including issue) fees.

Science.gov (United States)

2010-07-01

... entity $1,190.00 (d) Publication fee $300.00. (e) For filing an application for patent term adjustment... (including issue) fees. 1.18 Section 1.18 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions Fees...

Unresolved gamma rays from high-spin states

International Nuclear Information System (INIS)

Stephens, F.S.

1985-08-01

The γ-rays which are emitted from the highest spin states in nuclei cannot be resolved using present techniques. Nevertheless, methods are being developed to study nuclear structures in this spin range. For example, coincidence data has been used in the study of superdeformations and moments of inertia. While the general properties of these correlation plots are in accord with present expectations, there are several puzzling features of the data which require more study. One unresolved aspect concerns γ-ray energy spreads in a given decay pathway. In addition, higher-order correlation methods are in various stages of inception. 15 refs., 16 figs

UNR. A code for processing unresolved resonance data for MCNP

International Nuclear Information System (INIS)

Hogenbirk, A.

1994-09-01

In neutron transport problems the correct treatment of self-shielding is important for those nuclei present in large concentrations. Monte Carlo calculations using continuous-energy cross section data, such as calculations with the code MCNP, offer the advantage that neutron transport is calculated in a very accurate way. Self-shielding in the resolved resonance region is taken into account exactly in MCNP. However, self-shielding in the unresolved resonance region can not be taken into account by MCNP, although the effect of it may be important in many applications. In this report a description is given of the computer code UNR. With this code problem-dependent cross section libraries can be produced for MCNP. In these libraries self-shielded cross section data in the unresolved resonance range are given, which are produced by NJOY-module UNRESR. It is noted, that the treatment for resonance self-shielding presented in this report is approximate. However, the current version of MCNP does not allow the use of probability tables, which would be a general solution. (orig.)

Answering unresolved questions about the relationship between cognitive ability and prejudice

NARCIS (Netherlands)

Brandt, M.J.; Crawford, Jarret T

2016-01-01

Previous research finds that lower cognitive ability predicts greater prejudice. We test two unresolved questions about this association using a heterogeneous set of target groups and data from a representative sample of the United States (N = 5,914). First, we test “who are the targets of

Security issues in mobile NFC devices

CERN Document Server

Roland, Michael

2015-01-01

This work provides an assessment of the current state of near field communication (NFC) security, it reports on new attack scenarios, and offers concepts and solutions to overcome any unresolved issues. The work describes application-specific security aspects of NFC based on exemplary use-case scenarios and uses these to focus on the interaction with NFC tags and on card emulation. The current security architectures of NFC-enabled cellular phones are evaluated with regard to the identified security aspects.

TUZ, Resonance Integrals in Unresolved Region, Various Temperature, From Porter-Thomas Distribution

International Nuclear Information System (INIS)

Kuncir, G.F.

1969-01-01

1 - Nature of physical problem solved: TUZ computes resonance integrals for a wide variety of temperatures, compositions, and geometries for the unresolved resonances. 2 - Method of solution: The resonances are considered to be defined by an average over the Porter-Thomas distribution of neutron widths

New Theoretical Estimates of the Contribution of Unresolved Star-Forming Galaxies to the Extragalactic Gamma-Ray Background (EGB) as Measured by EGRET and the Fermi-LAT

Science.gov (United States)

Venters, Tonia M.

2011-01-01

We present new theoretical estimates of the contribution of unresolved star-forming galaxies to the extragalactic gamma-ray background (EGB) as measured by EGRET and the Fermi-LAT. We employ several methods for determining the star-forming galaxy contribution the the EGB, including a method positing a correlation between the gamma-ray luminosity of a galaxy and its rate of star formation as calculated from the total infrared luminosity, and a method that makes use of a model of the evolution of the galaxy gas mass with cosmic time. We find that depending on the model, unresolved star-forming galaxies could contribute significantly to the EGB as measured by the Fermi-LAT at energies between approx. 300 MeV and approx. few GeV. However, the overall spectrum of unresolved star-forming galaxies can explain neither the EGRET EGB spectrum at energies between 50 and 200 MeV nor the Fermi-LAT EGB spectrum at energies above approx. few GeV.

A SUB-GRID VOLUME-OF-FLUIDS (VOF) MODEL FOR MIXING IN RESOLVED SCALE AND IN UNRESOLVED SCALE COMPUTATIONS

International Nuclear Information System (INIS)

Vold, Erik L.; Scannapieco, Tony J.

2007-01-01

A sub-grid mix model based on a volume-of-fluids (VOF) representation is described for computational simulations of the transient mixing between reactive fluids, in which the atomically mixed components enter into the reactivity. The multi-fluid model allows each fluid species to have independent values for density, energy, pressure and temperature, as well as independent velocities and volume fractions. Fluid volume fractions are further divided into mix components to represent their 'mixedness' for more accurate prediction of reactivity. Time dependent conversion from unmixed volume fractions (denoted cf) to atomically mixed (af) fluids by diffusive processes is represented in resolved scale simulations with the volume fractions (cf, af mix). In unresolved scale simulations, the transition to atomically mixed materials begins with a conversion from unmixed material to a sub-grid volume fraction (pf). This fraction represents the unresolved small scales in the fluids, heterogeneously mixed by turbulent or multi-phase mixing processes, and this fraction then proceeds in a second step to the atomically mixed fraction by diffusion (cf, pf, af mix). Species velocities are evaluated with a species drift flux, ρ i u di = ρ i (u i -u), used to describe the fluid mixing sources in several closure options. A simple example of mixing fluids during 'interfacial deceleration mixing with a small amount of diffusion illustrates the generation of atomically mixed fluids in two cases, for resolved scale simulations and for unresolved scale simulations. Application to reactive mixing, including Inertial Confinement Fusion (ICF), is planned for future work.

Distribution of unresolvable anisotropic microstructures revealed in visibility-contrast images using x-ray Talbot interferometry

International Nuclear Information System (INIS)

Yashiro, Wataru; Harasse, Sebastien; Kawabata, Katsuyuki; Kuwabara, Hiroaki; Yamazaki, Takashi; Momose, Atsushi

2011-01-01

X-ray Talbot interferometry has been widely used as a technique for x-ray phase imaging and tomography. We propose a method using this interferometry for mapping distribution of parameters characterizing anisotropic microstructures, which are typically of the order of μm in size and cannot be resolved by the imaging system, in a sample. The method uses reduction in fringe visibility, which is caused by such unresolvable microstructures, in moire images obtained using an interferometer. We applied the method to a chloroprene rubber sponge sample, which exhibited uniaxial anisotropy of reduced visibility. We measured the dependencies of reduced visibility on both the Talbot order and the orientation of the sample and obtained maps of three parameters and their anisotropies that characterize the unresolvable anisotropic microstructures in the sample. The maps indicated that the anisotropy of the sample's visibility contrast mainly originated from the anisotropy of the microstructure elements' average size. Our method directly provides structural information on unresolvable microstructures in real space, which is only accessible through the ultra-small-angle x-ray scattering measurements in reciprocal space, and is expected to be broadly applied to material, biological, and medical sciences.

An overview of the BWR ECCS strainer blockage issues

International Nuclear Information System (INIS)

Serkiz, A.W.; Marshall, M.L. Jr.; Elliott, R.

1996-01-01

This Paper provides a brief overview of actions taken in the mid 1980s to resolve Unresolved Safety Issue (USI) A-43, open-quotes Containment Emergency Sump Performance,close quotes and their relationship to the BWR strainer blockage issue; the importance of insights gained from the Barseback-2 (a Swedish BWR) incident in 1992 and from ECCS strainer testing and inspections at the Perry nuclear power plant in 1992 and 1993; an analysis of an US BWR/4 with a Mark I containment; an international community sharing of knowledge relevant to ECCS strainer blockage, additional experimental programs; and identification of actions needed to resolve the strainer blockage issue and the status of such efforts

Simulated cosmic microwave background maps at 0.5 deg resolution: Unresolved features

Science.gov (United States)

Kogut, A.; Hinshaw, G.; Bennett, C. L.

1995-01-01

High-contrast peaks in the cosmic microwave background (CMB) anisotropy can appear as unresolved sources to observers. We fit simluated CMB maps generated with a cold dark matter model to a set of unresolved features at instrumental resolution 0.5 deg-1.5 deg to derive the integral number density per steradian n (greater than absolute value of T) of features brighter than threshold temperature absolute value of T and compare the results to recent experiments. A typical medium-scale experiment observing 0.001 sr at 0.5 deg resolution would expect to observe one feature brighter than 85 micro-K after convolution with the beam profile, with less than 5% probability to observe a source brighter than 150 micro-K. Increasing the power-law index of primordial density perturbations n from 1 to 1.5 raises these temperature limits absolute value of T by a factor of 2. The MSAM features are in agreement with standard cold dark matter models and are not necessarily evidence for processes beyond the standard model.

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

NARCIS (Netherlands)

Hu, H; Haas, S.A.; Chelly, J.; Esch, H. Van; Raynaud, M.; Brouwer, A.P. de; Weinert, S.; Froyen, G.; Frints, S.G.; Laumonnier, F.; Zemojtel, T.; Love, M.I.; Richard, H.; Emde, A.K.; Bienek, M.; Jensen, C.; Hambrock, M.; Fischer, U.; Langnick, C.; Feldkamp, M.; Wissink-Lindhout, W.; Lebrun, N.; Castelnau, L.; Rucci, J.; Montjean, R.; Dorseuil, O.; Billuart, P.; Stuhlmann, T.; Shaw, M.; Corbett, M.A.; Gardner, A.; Willis-Owen, S.; Tan, C.; Friend, K.L.; Belet, S.; Roozendaal, K.E. van; Jimenez-Pocquet, M.; Moizard, M.P.; Ronce, N.; Sun, R.; O'Keeffe, S.; Chenna, R.; Bommel, A. van; Goke, J.; Hackett, A.; Field, M.; Christie, L.; Boyle, J.; Haan, E.; Nelson, J.; Turner, G.; Baynam, G.; Gillessen-Kaesbach, G.; Muller, U.; Steinberger, D.; Budny, B.; Badura-Stronka, M.; Latos-Bielenska, A.; Ousager, L.B.; Wieacker, P.; Rodriguez Criado, G.; Bondeson, M.L.; Anneren, G.; Dufke, A.; Cohen, M.; Maldergem, L. Van; Vincent-Delorme, C.; Echenne, B.; Simon-Bouy, B.; Kleefstra, T.; Willemsen, M.H.; Fryns, J.P.; Devriendt, K.; Ullmann, R.; Vingron, M.; Wrogemann, K.; Wienker, T.F.; Tzschach, A.; Bokhoven, H. van; Gecz, J.; Jentsch, T.J.; Chen, W.; Ropers, H.H.; Kalscheuer, V.M.

2016-01-01

X-linked intellectual disability (XLID) is a clinically and genetically heterogeneous disorder. During the past two decades in excess of 100 X-chromosome ID genes have been identified. Yet, a large number of families mapping to the X-chromosome remained unresolved suggesting that more XLID genes or

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

DEFF Research Database (Denmark)

Hu, H; Haas, S A; Chelly, J

2016-01-01

X-linked intellectual disability (XLID) is a clinically and genetically heterogeneous disorder. During the past two decades in excess of 100 X-chromosome ID genes have been identified. Yet, a large number of families mapping to the X-chromosome remained unresolved suggesting that more XLID genes...

Parameterizing unresolved obstacles with source terms in wave modeling: A real-world application

Science.gov (United States)

Mentaschi, Lorenzo; Kakoulaki, Georgia; Vousdoukas, Michalis; Voukouvalas, Evangelos; Feyen, Luc; Besio, Giovanni

2018-06-01

Parameterizing the dissipative effects of small, unresolved coastal features, is fundamental to improve the skills of wave models. The established technique to deal with this problem consists in reducing the amount of energy advected within the propagation scheme, and is currently available only for regular grids. To find a more general approach, Mentaschi et al., 2015b formulated a technique based on source terms, and validated it on synthetic case studies. This technique separates the parameterization of the unresolved features from the energy advection, and can therefore be applied to any numerical scheme and to any type of mesh. Here we developed an open-source library for the estimation of the transparency coefficients needed by this approach, from bathymetric data and for any type of mesh. The spectral wave model WAVEWATCH III was used to show that in a real-world domain, such as the Caribbean Sea, the proposed approach has skills comparable and sometimes better than the established propagation-based technique.

Introduction to theory and analysis of resolved (and unresolved) neutron resonances via SAMMY

Energy Technology Data Exchange (ETDEWEB)

Larson, N.M.

1998-07-01

Neutron cross-section data are important for two distinct purposes: first, they provide insight into the nature of matter, thus assisting in the understanding of fundamental physics; second, they are needed for practical applications (e.g., for calculating when and how a reactor will become critical, or how much shielding is needed for storage of nuclear materials, and for medical applications). Neutron cross section data in the resolved-resonance region are generally obtained by time-of-flight experiments, which must be carefully analyzed if they are to be properly understood and utilized. In this paper, important features of the analysis process are discussed, with emphasis on the particular technique used in the analysis code SAMMY. Other features of the code are also described; these include such topics as calculation of group cross sections (including covariance matrices), generation and fitting of integral quantities, and extensions into the unresolved-resonance region and higher-energy regions.

Assessing 1D Atmospheric Solar Radiative Transfer Models: Interpretation and Handling of Unresolved Clouds.

Science.gov (United States)

Barker, H. W.; Stephens, G. L.; Partain, P. T.; Bergman, J. W.; Bonnel, B.; Campana, K.; Clothiaux, E. E.; Clough, S.; Cusack, S.; Delamere, J.; Edwards, J.; Evans, K. F.; Fouquart, Y.; Freidenreich, S.; Galin, V.; Hou, Y.; Kato, S.; Li, J.;  Mlawer, E.;  Morcrette, J.-J.;  O'Hirok, W.;  Räisänen, P.;  Ramaswamy, V.;  Ritter, B.;  Rozanov, E.;  Schlesinger, M.;  Shibata, K.;  Sporyshev, P.;  Sun, Z.;  Wendisch, M.;  Wood, N.;  Yang, F.

2003-08-01

The primary purpose of this study is to assess the performance of 1D solar radiative transfer codes that are used currently both for research and in weather and climate models. Emphasis is on interpretation and handling of unresolved clouds. Answers are sought to the following questions: (i) How well do 1D solar codes interpret and handle columns of information pertaining to partly cloudy atmospheres? (ii) Regardless of the adequacy of their assumptions about unresolved clouds, do 1D solar codes perform as intended?One clear-sky and two plane-parallel, homogeneous (PPH) overcast cloud cases serve to elucidate 1D model differences due to varying treatments of gaseous transmittances, cloud optical properties, and basic radiative transfer. The remaining four cases involve 3D distributions of cloud water and water vapor as simulated by cloud-resolving models. Results for 25 1D codes, which included two line-by-line (LBL) models (clear and overcast only) and four 3D Monte Carlo (MC) photon transport algorithms, were submitted by 22 groups. Benchmark, domain-averaged irradiance profiles were computed by the MC codes. For the clear and overcast cases, all MC estimates of top-of-atmosphere albedo, atmospheric absorptance, and surface absorptance agree with one of the LBL codes to within ±2%. Most 1D codes underestimate atmospheric absorptance by typically 15-25 W m-2 at overhead sun for the standard tropical atmosphere regardless of clouds.Depending on assumptions about unresolved clouds, the 1D codes were partitioned into four genres: (i) horizontal variability, (ii) exact overlap of PPH clouds, (iii) maximum/random overlap of PPH clouds, and (iv) random overlap of PPH clouds. A single MC code was used to establish conditional benchmarks applicable to each genre, and all MC codes were used to establish the full 3D benchmarks. There is a tendency for 1D codes to cluster near their respective conditional benchmarks, though intragenre variances typically exceed those for

A CATALOG OF NEAR-IR SOURCES FOUND TO BE UNRESOLVED WITH MILLIARCSECOND RESOLUTION

Energy Technology Data Exchange (ETDEWEB)

Richichi, A. [National Astronomical Research Institute of Thailand, 191 Siriphanich Bldg., Huay Kaew Rd., Suthep, Muang, Chiang Mai 50200 (Thailand); Fors, O. [Departament Astronomia i Meteorologia and Institut de Ciencies del Cosmos (ICC), Universitat de Barcelona (UB/IEEC), Marti i Franques 1, E-08028 Barcelona (Spain); Cusano, F. [INAF-Osservatorio Astronomico di Bologna, Via Ranzani 1, I-40127 Bologna (Italy); Moerchen, M., E-mail: andrea@narit.or.th [European Southern Observatory, Casilla 19001, Santiago 19 (Chile)

2012-12-15

Calibration is one of the long-standing problems in optical interferometric measurements, particularly with long baselines which demand stars with angular sizes on the milliarcsecond scale and no detectable companions. While systems of calibrators have been generally established for the near-infrared in the bright source regime (K {approx}< 3 mag), modern large interferometers are sensitive to significantly fainter magnitudes. We aim to provide a list of sources found to be unresolved from direct observations with high angular resolution and dynamic range, which can be used to choose interferometric calibrators. To this purpose, we have used a large number of lunar occultations recorded with the ISAAC instrument at the Very Large Telescope to select sources found to be unresolved and without close companions. An algorithm has been used to determine the limiting angular resolution achieved for each source, taking into account a noise model built from occulted and unocculted portions of the light curves. We have obtained upper limits on the angular sizes of 556 sources, with magnitudes ranging from K{sub s} Almost-Equal-To 4 to 10, with a median of 7.2 mag. The upper limits on possible undetected companions (within Almost-Equal-To 0.''5) range from K{sub s} Almost-Equal-To 8 to 13, with a median of 11.5 mag. One-third of the sources have angular sizes {<=}1 mas, and two-thirds have sizes {<=}2 mas. This list of unresolved sources matches well the capabilities of current large interferometric facilities. We also provide available cross-identifications, magnitudes, spectral types, and other auxiliary information. A fraction of the sources are found to be potentially variable. The list covers parts of the Galactic Bulge and in particular the vicinity of the Galactic Center, where extinction is very significant and traditional lists of calibrators are often insufficient.

Unresolved Issues for Utilization of Atypical Antipsychotics in Schizophrenia: Antipsychotic Polypharmacy and Metabolic Syndrome

Directory of Open Access Journals (Sweden)

Sang Won Jeon

2017-10-01

Full Text Available Atypical antipsychotics (AAP are the prevailing form of schizophrenia treatment today due to their low side effects and superior efficacy. Nevertheless, some issues still need to be addressed. First, there are still a large number of patients with treatment-resistant schizophrenia (TRS, which has led to a growing trend to resort to AAP polypharmacy with few side effects. Most clinical treatment guidelines recommend clozapine monotherapy in TRS, but around one third of schizophrenic patients fail to respond to clozapine. For these patients, with clozapine-resistant schizophrenia AAP polypharmacy is a common strategy with a continually growing evidence base. Second, AAP generally have great risks for developing metabolic syndrome, such as weight gain, abnormality in glucose, and lipid metabolism. These metabolic side effects have become huge stumbling blocks in today’s schizophrenia treatment that aims to improve patients’ quality of life as well as symptoms. The exact reasons why this particular syndrome occurs in patients treated with AAP is as yet unclear though factors such as interaction of AAP with neurotransmitter receptors, genetic pholymorphisms, type of AAPs, length of AAP use, and life style of schizophrenic patients that may contribute to its development. The present article aimed to review the evidence underlying these key issues and provide the most reasonable interpretations to expand the overall scope of antipsychotics usage.

Proceedings of the Hydrokinetic and Wave Energy Technologies Technical and Environmental Issues Workshop

Energy Technology Data Exchange (ETDEWEB)

None

2006-03-01

Renewable energy technologies offer the promise of non-polluting alternatives to fossil and nuclear-fueled power plants to meet growing demand for electrical energy. Two emerging categories of renewable energy technologies, hydrokinetic and wave energy conversion devices, offer ways to tap the energy of moving water without impoundment (dams) or diversion required by many conventional hydroelectric facilities. These technologies include devices designed for deployment in natural streams, tidal estuaries, ocean currents, and constructed waterways, as well as devices designed to capture the energy of ocean waves. On October 26-28, 2005, 54 representatives from government, non-governmental organizations, and private business met to (1) identify the varieties of hydrokinetic energy and wave technology devices, their stages of development, and the projected cost to bring each to market; (2) identify where these technologies can best operate; (3) identify the potential environmental issues associated with these technologies and possible mitigation measures; (4) develop a list of research needs and/or practical solutions to address unresolved environmental issues. These workshop proceedings include detailed summaries of the 24 presentations made and the discussions that followed.

Absorption and emission profiles of unresolved arrays near local thermodynamic equilibrium

Energy Technology Data Exchange (ETDEWEB)

Busquet, M.; Klapisch, M. E-mail: klapisch@this.nrl.navy.mil; Bar-Shalom, A

2003-11-01

The absorption and emission arrays in the unresolved transition array (UTA) and super transition array (STA) models are usually assumed to have the same Gaussian spectral shape. It is shown, starting from a Boltzmann population distribution, that the assumption of profile identity for both absorption and emission is inconsistent with Kirchhoff's law. A correcting formula is established. It is extended to the cases where one or two effective population temperatures are involved. Examples are shown where the effect is noticeable.

Absorption and emission profiles of unresolved arrays near local thermodynamic equilibrium

International Nuclear Information System (INIS)

Busquet, M.; Klapisch, M.; Bar-Shalom, A.

2003-01-01

The absorption and emission arrays in the unresolved transition array (UTA) and super transition array (STA) models are usually assumed to have the same Gaussian spectral shape. It is shown, starting from a Boltzmann population distribution, that the assumption of profile identity for both absorption and emission is inconsistent with Kirchhoff's law. A correcting formula is established. It is extended to the cases where one or two effective population temperatures are involved. Examples are shown where the effect is noticeable

Testing of cross-section functionals in the unresolved resonance region

International Nuclear Information System (INIS)

Koshcheev, V.N.; Krivtsov, A.S.; Sinitsa, V.V.; Ukraintsev, V.F.

1994-01-01

The results of a comparison of the GRUCON, MMK and NJOY data processing codes in the treatment of evaluated neutron data in the unresolved resonance region are presented. The sets of average resonance parameters of 238 U and 239 Pu isotopes, which have been published by Munos-Cobos et al., and Ribon et al., were used in this exercise. Average cross-sections, self-shielding factors and Doppler broadening self-shielding factors are compared with the original results presented by the above-mentioned authors. Conclusions regarding the reliability of the neutron data processing codes are made. (author). 6 refs, 7 tabs

Brainstem auditory responses to resolved and unresolved harmonics of a synthetic vowel in quiet and noise.

Science.gov (United States)

Laroche, Marilyn; Dajani, Hilmi R; Prévost, François; Marcoux, André M

2013-01-01

This study investigated speech auditory brainstem responses (speech ABR) with variants of a synthetic vowel in quiet and in background noise. Its objectives were to study the noise robustness of the brainstem response at the fundamental frequency F0 and at the first formant F1, evaluate how the resolved/unresolved harmonics regions in speech contribute to the response at F0, and investigate the origin of the response at F0 to resolved and unresolved harmonics in speech. In total, 18 normal-hearing subjects (11 women, aged 18-33 years) participated in this study. Speech ABRs were recorded using variants of a 300 msec formant-synthesized /a/ vowel in quiet and in white noise. The first experiment employed three variants containing the first three formants F1 to F3, F1 only, and F2 and F3 only with relative formant levels following those reported in the literature. The second experiment employed three variants containing F1 only, F2 only, and F3 only, with the formants equalized to the same level and the signal-to-noise ratio (SNR) maintained at -5 dB. Overall response latency was estimated, and the amplitude and local SNR of the envelope following response at F0 and of the frequency following response at F1 were compared for the different stimulus variants in quiet and in noise. The response at F0 was more robust to noise than that at F1. There were no statistically significant differences in the response at F0 caused by the three stimulus variants in both experiments in quiet. However, the response at F0 with the variant dominated by resolved harmonics was more robust to noise than the response at F0 with the stimulus variants dominated by unresolved harmonics. The latencies of the responses in all cases were very similar in quiet, but the responses at F0 due to resolved and unresolved harmonics combined nonlinearly when both were present in the stimulus. Speech ABR has been suggested as a marker of central auditory processing. The results of this study support

Accounting for model error due to unresolved scales within ensemble Kalman filtering

OpenAIRE

Mitchell, Lewis; Carrassi, Alberto

2014-01-01

We propose a method to account for model error due to unresolved scales in the context of the ensemble transform Kalman filter (ETKF). The approach extends to this class of algorithms the deterministic model error formulation recently explored for variational schemes and extended Kalman filter. The model error statistic required in the analysis update is estimated using historical reanalysis increments and a suitable model error evolution law. Two different versions of the method are describe...

Matching of singly- and doubly-unresolved limits of tree-level QCD squared matrix elements

Energy Technology Data Exchange (ETDEWEB)

Somogyi, Gabor [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary); Trocsanyi, Zoltan [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary); Duca, Vittorio Del [Istituto Nazionale di Fisica Nucleare, Sez. di Torino, via P. Giuria, 1 - 10125 Torino (Italy)

2005-06-01

We describe how to disentangle the singly- and doubly-unresolved (soft and/or collinear) limits of tree-level QCD squared matrix elements. Using the factorization formulae presented in this paper, we outline a viable general subtraction scheme for computing next-to-next-to-leading order corrections for electron-positron annihilation into jets.

Integration of collinear-type doubly unresolved counterterms in NNLO jet cross sections

Science.gov (United States)

Del Duca, Vittorio; Somogyi, Gábor; Trócsányi, Zoltán

2013-06-01

In the context of a subtraction method for jet cross sections at NNLO accuracy in the strong coupling, we perform the integration over the two-particle factorised phase space of the collinear-type contributions to the doubly unresolved counterterms. We present the final result as a convolution in colour space of the Born cross section and of an insertion operator, which is written in terms of master integrals that we expand in the dimensional regularisation parameter.

Integration of collinear-type doubly unresolved counterterms in NNLO jet cross sections

CERN Document Server

Del Duca, Vittorio; Trocsanyi, Zoltan

2013-01-01

In the context of a subtraction method for jet cross sections at NNLO accuracy in the strong coupling, we perform the integration over the two-particle factorised phase space of the collinear-type contributions to the doubly unresolved counterterms. We present the final result as a convolution in colour space of the Born cross section and of an insertion operator, which is written in terms of master integrals that we expand in the dimensional regularisation parameter.

Assessment of the Unresolved Resonance Treatment for Cross-section and Covariance Representation. A report by the Working Party on International Evaluation Co-operation of the NEA Nuclear Science Committee

International Nuclear Information System (INIS)

Leal, L.; Shibata, K.; Iwamoto, O.; Chiba, G.; Noguere, G.; Saint Jean, C. de; Sirakov, I.; Capote, R.; Sublet, J.C.; Coste-Delclaux, M.; Jouanne, C.; MacFarlane, R.E.; Kahler, A.C. Jr.; Lubitz, C.R.; Cullen, D.; Herman, M.; Ribon, P.

2011-01-01

This report summarises the work performed under WPEC Subgroup 32 (SG32) on issues pertinent to the methodology used in the unresolved resonance region (URR). The main purpose of SG32 was to verify the validity of the Single-level Breit-Wigner (SLBW) cross-section representation in the URR for self-shielding calculations. While SG32 work was under way, several other developments related to the URR on this subject came into play that had a direct impact on the results of calculations. The work described in this report focuses on: - testing of the SLBW formalism in the URR for fissile and fertile isotopes; - URR covariance representation; - interpolation issue with a URR resonance parameter for the infinitely dilute cross-section calculations; - ENDF URR parameter representation based on the LSSF = 0 or LSSF = 1 option

A subtraction scheme for computing QCD jet cross sections at NNLO. Integrating the iterated singly-unresolved subtraction terms

Energy Technology Data Exchange (ETDEWEB)

Bolzoni, Paolo [Hamburg Univ. (Germany). II. Inst. fuer Theoretische Physik; Somogyi, Gabor [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Trocsanyi, Zoltan [Debrecen Univ. (Hungary); Hungarian Academy of Sciences, Debrecen (Hungary). Inst. of Nuclear Research

2010-11-15

We perform the integration of all iterated singly-unresolved subtraction terms over the two-particle factorized phase space. We also sum over the unresolved parton flavours. The final result can be written as a convolution (in colour space) of the Born cross section and an insertion operator. We spell out the insertion operator in terms of 24 basic integrals that are defined explicitly. We compute the coefficients of the Laurent-expansion of these integrals in two different ways, with the method of Mellin-Barnes representations and sector decomposition. Finally, we present the Laurentexpansion of the full insertion operator for the specific examples of electron-positron annihilation into two and three jets. (orig.)

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the iterated singly-unresolved subtraction terms

Science.gov (United States)

Bolzoni, Paolo; Somogyi, Gábor; Trócsányi, Zoltán

2011-01-01

We perform the integration of all iterated singly-unresolved subtraction terms, as defined in ref. [1], over the two-particle factorized phase space. We also sum over the unresolved parton flavours. The final result can be written as a convolution (in colour space) of the Born cross section and an insertion operator. We spell out the insertion operator in terms of 24 basic integrals that are defined explicitly. We compute the coefficients of the Laurent expansion of these integrals in two different ways, with the method of Mellin-Barnes representations and sector decomposition. Finally, we present the Laurent-expansion of the full insertion operator for the specific examples of electron-positron annihilation into two and three jets.

Auxiliary-cavity-assisted ground-state cooling of an optically levitated nanosphere in the unresolved-sideband regime

Science.gov (United States)

Feng, Jin-Shan; Tan, Lei; Gu, Huai-Qiang; Liu, Wu-Ming

2017-12-01

We theoretically analyze the ground-state cooling of an optically levitated nanosphere in the unresolved-sideband regime by introducing a coupled high-quality-factor cavity. On account of the quantum interference stemming from the presence of the coupled cavity, the spectral density of the optical force exerting on the nanosphere gets changed and then the symmetry between the heating and the cooling processes is broken. Through adjusting the detuning of a strong-dissipative cavity mode, one obtains an enhanced net cooling rate for the nanosphere. It is illustrated that the ground-state cooling can be realized in the unresolved sideband regime even if the effective optomechanical coupling is weaker than the frequency of the nanosphere, which can be understood by the picture that the effective interplay of the nanosphere and the auxiliary cavity mode brings the system back to an effective resolved regime. Besides, the coupled cavity refines the dynamical stability of the system.

The effect of the 238U neutron strength function uncertainty on resonance structure calculations in unresolved regions

International Nuclear Information System (INIS)

Koshcheev, V.N.; Manturov, G.N.; Sinitsa, V.V.

1991-01-01

The effects of the neutron strength function uncertainties on the calculated values of the self-shielding factors and energy dependence of the total and capture 238 U cross-sections in the unresolved resonance region are investigated. (author). 26 refs, 5 figs

Assessing stakeholder's experience and sensitivity on key issues for the economic growth of organic aquaculture production

DEFF Research Database (Denmark)

Lembo, Giuseppe; Jokumsen, Alfred; Spedicato, Maria Teresa

2018-01-01

expressed by the participants revealed both competence and awareness, despite the complexity of the subject. Several ideas and useful suggestions emerged regarding unresolved technical issues. In addition, the need for a targeted communication strategy on the quality of organic aquaculture products...... and the necessity of fostering European/national programs to support the production and marketing of organic aquaculture products were highlighted...

Report on the Workshop Resolved and Unresolved Stellar PopUlaTIoNs (RASPUTIN)

Science.gov (United States)

Bono, G.; Valenti, E.

2014-12-01

The workshop aimed at sharing and discussing observations and diagnostics, together with models and simulations, of the resolved and unresolved stellar populations in galaxies from the Milky Way to the distant Universe. Special attention was paid to recent results concerning galaxy formation and evolution, fostering the exchange of ideas and techniques in dealing with nearby stellar populations. There will be no published proceedings, but presentations are available for download from the workshop web page (www.eso.org/sci/meetings/2014/rasputin2014).

[Materiality Analysis of Health Plans Based on Stakeholder Engagement and the Issues Included at ISO 26000:2010].

Science.gov (United States)

Moyano Santiago, Miguel Angel; Rivera Lirio, Juana María

2017-01-18

Health plans of the Spanish autonomous communities can incorporate sustainable development criteria in its development. There have been no analysis or proposals about development and indicators. The goal is to add a contribution to help build better health plans aimed at sustainable development and help to manage economic, social and environmental impacts of health systems criteria. We used a variation of the RAND/UCLA or modified Delphi technique method. The process consisted of a bibliographical and context matters and issues related to health and social responsibility analysis based on ISO 26000: 2010. A survey by deliberately to a selection of 70 expert members of the identified stakeholders was carried out and a discussion group was held to determine the consensus on the issues addressed in the survey sample. The research was conducted in 2015. From the literature review 33 health issues included in ISO 26000:2010 were obtained. 7 survey proved relevant high consensus, 8 relevance and average consensus and 18 with less relevance and high level of dissent. The expert group excluded 4 of the 18 subjects with less consensus. 29 issues included 33 at work, divided into 7 subjects contained in the guide ISO 26000 of social responsibility, were relevant stakeholders regarding possible inclusion in health plans. Considering the direct relationship published by ISO (International Organization for Standardization) among the issues ISO 26000 and the economic, social and environmental indicators in GRI (Global Reporting Initiative) in its G4 version, a panel with monitoring indicators related to relevant issues were elaborated.

Astrophysical interpretation of the anisotropies in the unresolved gamma-ray background

Science.gov (United States)

Ando, Shin'ichiro; Fornasa, Mattia; Fornengo, Nicolao; Regis, Marco; Zechlin, Hannes-S.

2017-06-01

Recently, a new measurement of the auto- and cross-correlation angular power spectrum (APS) of the isotropic gamma-ray background was performed, based on 81 months of data of the Fermi Large-Area Telescope (LAT). Here, we fit, for the first time, the new APS data with a model describing the emission of unresolved blazars. These sources are expected to dominate the anisotropy signal. The model we employ in our analysis reproduces well the blazars resolved by Fermi LAT. When considering the APS obtained by masking the sources listed in the 3FGL catalog, we find that unresolved blazars underproduce the measured APS below ˜1 GeV . Contrary to past results, this suggests the presence of a new contribution to the low-energy APS, with a significance of, at least, 5 σ . The excess can be ascribed to a new class of faint gamma-ray emitters. If we consider the APS obtained by masking the sources in the 2FGL catalog, there is no underproduction of the APS below 1 GeV, but the new source class is still preferred over the blazars-only scenario (with a significance larger than 10 σ ). The properties of the new source class and the level of anisotropies induced in the isotropic gamma-ray background are the same, independent of the APS data used. In particular, the new gamma-ray emitters must have a soft energy spectrum, with a spectral index ranging, approximately, from 2.7 to 3.2. This complicates their interpretation in terms of known sources, since, normally, star-forming and radio galaxies are observed with a harder spectrum. The new source class identified here is also expected to contribute significantly to the intensity of the isotropic gamma-ray background.

A high-significance measurement of correlation between unresolved IRAS sources and optically-selected galaxy clusters

Energy Technology Data Exchange (ETDEWEB)

Hincks, Adam D.; Hajian, Amir [Canadian Institute for Theoretical Astrophysics, University of Toronto, Toronto, ON M5S 3H8 (Canada); Addison, Graeme E., E-mail: hincks@cita.utoronto.ca, E-mail: ahajian@cita.utoronto.ca, E-mail: gaddison@phas.ubc.ca [Department of Physics and Astronomy, University of British Columbia, Vancouver, BC V6T 1Z4 (Canada)

2013-05-01

We cross-correlate the 100 μm Improved Reprocessing of the IRAS Survey (IRIS) map and galaxy clusters at 0.1 < z < 0.3 in the maxBCG catalogue taken from the Sloan Digital Sky Survey, measuring an angular cross-power spectrum over multipole moments 150 < l < 3000 at a total significance of over 40σ. The cross-spectrum, which arises from the spatial correlation between unresolved dusty galaxies that make up the cosmic infrared background (CIB) in the IRIS map and the galaxy clusters, is well-fit by a single power law with an index of −1.28±0.12, similar to the clustering of unresolved galaxies from cross-correlating far-infrared and submillimetre maps at longer wavelengths. Using a recent, phenomenological model for the spectral and clustering properties of the IRIS galaxies, we constrain the large-scale bias of the maxBCG clusters to be 2.6±1.4, consistent with existing analyses of the real-space cluster correlation function. The success of our method suggests that future CIB-optical cross-correlations using Planck and Herschel data will significantly improve our understanding of the clustering and redshift distribution of the faint CIB sources.

Status of safety issues at licensed power plants

International Nuclear Information System (INIS)

1991-06-01

As part of ongoing US Nuclear Regulatory Commission (NRC) efforts to ensure the quality and accountability of safety issue information, a program has been established whereby an annual NUREG report will be published on the status of licensee implementation and NRC verification of safety issues in major NRC requirement areas. This report, the third volume of a three-volume series, addresses the status of generic safety issues (GSIs) at licensed plants. Volume 1 addressed the status of Three Mile Island Action Plan requirements and was published in March 1991. Volume 2 addressed the status of implementation and verification of unresolved safety issues and was published in May 1991. The annual NUREG report will combine these three areas in a single volume to be published in late 1991. The data contained in these NUREG reports are a product of the NRC's Safety Issues Management System (SIMS) database, which is maintained by the Project Management Staff in the Office of Nuclear Reactor Regulation and by NRC regional personnel. The purpose of this report is to provide a comprehensive description of the status of implementation and verification of the 34 GSIs and sub-issues that have been resolved by the NRC and involve implementation of an action or actions by licensees. This NUREG report also serves as a follow-on to NUREG-0933, ''A Prioritization of Generic Safety Issues,'' which tracks safety issues up until a request for action by licensees is issued by NRC. 3 figs., 6 tabs

Unresolved issues in theories of autoimmune disease using myocarditis as a framework

OpenAIRE

Root-Bernstein, Robert; Fairweather, DeLisa

2014-01-01

Many theories of autoimmune disease have been proposed since the discovery that the immune system can attack the body. These theories include the hidden or cryptic antigen theory, modified antigen theory, T cell bypass, T cell-B cell mismatch, epitope spread or drift, the bystander effect, molecular mimicry, anti-idiotype theory, antigenic complementarity, and dual-affinity T cell receptors. We critically review these theories and relevant mathematical models as they apply to autoimmune myoca...

Ebola epidemic of 2014-2015: unresolved ethical issues.

Science.gov (United States)

Garbuglia, Anna Rosa

2016-01-01

Some ethical aspects of the management of the Ebola epidemic in Guinea, Liberia and Sierra Leone which started in January 2014, have been questionable. First, as regards the prevention of the spread of the virus, the necessary epidemiological investigations on the origin of the infection were not carried out adequately and this did not help to curb the spread of the disease. A disparity has been observed between the western and African countries' access to the treatment of patients; this infringes on the principle of equality. This paper also focuses on how the Global Public Goods for Health principle was not fully respected in the management of the epidemic.

Sensitization to fungal allergens: Resolved and unresolved issues

Directory of Open Access Journals (Sweden)

Yuma Fukutomi

2015-10-01

Despite its importance in the management of allergic diseases, precise recognition of species-specific IgE sensitization to fungal allergens is often challenging because the majority of fungal extracts exhibit broad cross-reactivity with taxonomically unrelated fungi. Recent progress in gene technology has contributed to the identification of specific and cross-reactive allergen components from different fungal sources. However, data demonstrating the clinical relevance of IgE reactivity to these allergen components are still insufficient.

Interim staff position on environmental qualification of safety-related electrical equipment: including staff responses to public comments. Regulatory report

International Nuclear Information System (INIS)

Szukiewicz, A.J.

1981-07-01

This document provides the NRC staff positions regarding selected areas of environmental qualification of safety-related electrical equipment, in the resolution of Unresolved Safety Issue A-24, 'Qualification of Class IE Safety-Related Equipment.' The positions herein are applicable to plants that are or will be in the construction permit (CP) or operating license (OL) review process and that are required to satisfy the requirements set forth in either the 1971 or the 1974 version of IEEE-323 standard

KBS Annual Report 1983. Including summaries of technical reports issued during 1983

International Nuclear Information System (INIS)

1984-06-01

The purpose of the KBS Annual Report is to inform interested organizations and individuals of the research and development work performed by the division KBS within the Swedish Nuclear Fuel Supply Co (SKBF) on the handling, treatment and final storage of nuclear wastes in Sweden. The Annual Report normally contains a presentation of the legal and organizational situation followed by an account of the progress within different areas of the R and D-work. This account also includes indications of the activities planned for the future. At the end of the report the summaries of 76 technical reports and other publications issued during the year are listed in special appendices. (K.A.E.)

Unresolved resonance self shielding calculation: causes and importance of discrepancies

International Nuclear Information System (INIS)

Ribon, P.; Tellier, H.

1986-01-01

To compute the self shielding coefficient, it is necessary to know the point-wise cross-sections. In the unresolved resonance region, the parameters of each level are not known; only the average parameters. Therefore the authors simulate the point-wise cross-section by random sampling of the energy levels and resonance parameters with respect to the Wigner law and the x 2 distributions, and by computing the cross-section in the same way as in the resolved regions. The result of this statistical calculation obviously depends on the initial parameters but also on the method of sampling, on the formalism which is used to compute the cross-section or on the weighting neutron flux. In this paper, the authors survey the main phenomena which can induce discrepancies in self shielding computations. Results are given for typical dilutions which occur in nuclear reactors

Contribution to the study of the unresolved resonance range of the neutrons cross sections

International Nuclear Information System (INIS)

Noguere, Gilles

2014-01-01

This document presents the statistical description of neutron cross sections in the unresolved resonance range. The modeling of the total cross section and of the 'shape - elastic' cross section is based on the 'average R-Matrix' formalism. The partial cross sections describing the radiative capture, elastic scattering, inelastic scattering and fission process are calculated using the Hauser-Feshbach formalism with width fluctuation corrections. In the unresolved resonance range, these models depend on the average resonance parameters (neutron strength function Sc, mean level spacing D c , average partial reaction widths Γ c , channel radius a c , effective radius R' and distant level parameter R-bar c ∞ ). The codes (NJOY, CALENDF...) dedicated to the processing of nuclear data libraries (JEFF, ENDF/B, JENDL, CENDL, BROND... ) use the average parameters to take into account the self-shielding phenomenon for the simulation of the neutron transport in Monte-Carlo (MCNP, TRIPOLI... ) and deterministic (APOLLO, ERANOS...) codes. The evaluation work consists in establishing a consistent set of average parameters as a function of the total angular momentum J of the system and of the orbital moment of the incident neutron l. The work presented in this paper aims to describe the links between the S-Matrix and the 'average R-Matrix' formalism for the calculation of Sc, R-bar c ∞ , ac and R'. (author) [fr

Unresolved tensions in consumer engagement in CER: a US research perspective.

Science.gov (United States)

Workman, Thomas; Maurer, Maureen; Carman, Kristin

2013-03-01

Efforts to engage patients and consumers in comparative effectiveness research (CER) in the USA are still in the early stages, and the outcomes of these partnerships have yet to be fully understood or realized. Our work assisting federal agencies and national organizations who engage patients and consumers in CER reveal three unresolved tensions around the representation of the patient experience in the research process, the culture of research and capacity to partner with patients and consumers, and the conflict between the methodological approaches to CER and the outcomes of interest to patients and caregivers. Several approaches to address these tensions have emerged, yet resolving these tensions will require addressing many system-level challenges and building an evidence base for consumer engagement in CER.

Validation of the XLACS code related to contribution of resolved and unresolved resonances and background cross sections

International Nuclear Information System (INIS)

Anaf, J.; Chalhoub, E.S.

1990-01-01

The procedures for calculating contributions of resolved and unresolved resonances and background cross sections, in XLACS code, were revised. Constant weighting function and zero Kelvin temperature were considered. Discrepancies found were corrected and now the validated XLACS code generates results that are correct and in accordance with its originally established procedures. (author)

In-stack condensible particulate matter measurement and permitting issues

International Nuclear Information System (INIS)

Corio, L.A.; Sherwell, J.

1997-01-01

Based on the results of recent epidemiological studies and assessments of the causes of visibility degradation, EPA is proposing to regulate PM2.5 emissions. PM can be classified as either filterable or condensible PM. Condensible PM includes sulfates, such as sulfuric acid. Sulfates typically account for at least half of the total dry fine PM mass in the atmosphere. Power plant SO x -based emissions make a significant contribution to ambient fine PM levels in the eastern US. Although much of this mass is derived from secondary chemical reactions in the atmosphere, a portion of this sulfate is emitted directly from stacks as condensible PM. The potential condensible PM fraction associated with coal-burning boiler emissions is somewhat uncertain. The characterization of PM emissions from these sources has been, until recently, based on in-stack filterable PM measurements only. To determine the relative magnitude of condensible PM emissions and better understand condensible PM measurement issues, a review and analysis of actual EPA Method 202 results and state-developed hybrid condensible PM methods were conducted. A review of available Method 202 results for several coal-burning boilers showed that the condensible PM, on average, comprises 60% of the total PM10. A review of recent results for state-developed measurement methods for condensible PM for numerous coal-burning boilers indicated that condensible PM accounted for, on average, approximately 49% of total PM. Caution should be exercised in the use of these results because of the seemingly unresolved issue of artifact formation, which may bias the Method 202 and state-developed methods results on the high side. Condensible PM10 measurement results and issues, and potential ramifications of including condensible PM10 emissions in the PSD permit review process are discussed. Selected power plants in Maryland are discussed as examples

Unresolved resonance self shielding calculation: causes and importance of discrepancies

International Nuclear Information System (INIS)

Ribon, P.; Tellier, H.

1986-09-01

To compute the self shielding coefficient, it is necessary to know the point-wise cross-sections. In the unresolved resonance region, we do not know the parameters of each level but only the average parameters. Therefore we simulate the point-wise cross-section by random sampling of the energy levels and resonance parameters with respect to the Wigner law and the X 2 distributions, and by computing the cross-section in the same way as in the resolved regions. The result of this statistical calculation obviously depends on the initial parameters but also on the method of sampling, on the formalism which is used to compute the cross-section or on the weighting neutron flux. In this paper, we will survey the main phenomena which can induce discrepancies in self shielding computations. Results are given for typical dilutions which occur in nuclear reactors. 8 refs

Status of thermalhydraulic modelling and assessment: Open issues

Energy Technology Data Exchange (ETDEWEB)

Bestion, D.; Barre, F. [CEA, Grenoble (France)

1997-07-01

This paper presents the status of the physical modelling in present codes used for Nuclear Reactor Thermalhydraulics (TRAC, RELAP 5, CATHARE, ATHLET,...) and attempts to list the unresolved or partially resolved issues. First, the capabilities and limitations of present codes are presented. They are mainly known from a synthesis of the assessment calculations performed for both separate effect tests and integral effect tests. It is also interesting to list all the assumptions and simplifications which were made in the establishment of the system of equations and of the constitutive relations. Many of the present limitations are associated to physical situations where these assumptions are not valid. Then, recommendations are proposed to extend the capabilities of these codes.

Status of thermalhydraulic modelling and assessment: Open issues

International Nuclear Information System (INIS)

Bestion, D.; Barre, F.

1997-01-01

This paper presents the status of the physical modelling in present codes used for Nuclear Reactor Thermalhydraulics (TRAC, RELAP 5, CATHARE, ATHLET,...) and attempts to list the unresolved or partially resolved issues. First, the capabilities and limitations of present codes are presented. They are mainly known from a synthesis of the assessment calculations performed for both separate effect tests and integral effect tests. It is also interesting to list all the assumptions and simplifications which were made in the establishment of the system of equations and of the constitutive relations. Many of the present limitations are associated to physical situations where these assumptions are not valid. Then, recommendations are proposed to extend the capabilities of these codes

Current issues relating to psychosocial job strain and cardiovascular disease research.

Science.gov (United States)

Theorell, T; Karasek, R A

1996-01-01

The authors comment on recent reviews of cardiovascular job strain research by P. L. Schnall and P. A. Landsbergis (1994), and by T. S. Kristensen (1995), which conclude that job strain as defined by the demand-control model (the combination of contributions of low job decision latitudes and high psychological job demands) is confirmed as a risk factor for cardiovascular mortality in a large majority of studies. Lack of social support at work appears to further increase risk. Several still-unresolved research questions are examined in light of recent studies: (a) methodological issues related to use of occupational aggregate estimations and occupational career aggregate assessments, use of standard scales for job analysis and recall bias issues in self-reporting; (b) confounding factors and differential strengths of association by subgroups in job strain-cardiovascular disease analyses with respect to social class, gender, and working hours; and (c) review of results of monitoring job strain-blood pressure associations and associated methodological issues.

Team Dynamics. Essays in the Sociology and Social Psychology of Sport Including Methodological and Epistemological Issues.

Science.gov (United States)

Lenk, Hans

This document contains nine essays on the sociology and social psychology of team dynamics, including methodological and epistemological issues involved in such study. Essay titles are: (1) Conflict and Achievement in Top Athletic Teams--Sociometric Structures of Racing Eight Oar Crews; (2) Top Performance Despite Internal Conflict--An Antithesis…

Optical model calculation for the unresolved/resolved resonance region of Fe-56

Energy Technology Data Exchange (ETDEWEB)

Kawano, Toshihiko [Kyushu Univ., Fukuoka (Japan); Froehner, F.H.

1997-03-01

We have studied optical model fits to total neutron cross sections of structural materials using the accurate data base for {sup 56}Fe existing in the resolved and unresolved resonance region. Averages over resolved resonances were calculated with Lorentzian weighting in Reich-Moore (reduced R matrix) approximation. Starting from the best available optical potentials we found that adjustment of the real and imaginary well depths does not work satisfactorily with the conventional weak linear energy dependence of the well depths. If, however, the linear dependences are modified towards low energies, the average total cross sections can be fitted quite well, from the resolved resonance region up to 20 MeV and higher. (author)

Present situation and problems of nuclear-security-related legislation in Japan

International Nuclear Information System (INIS)

Irie, Kazutomo

2013-01-01

This paper shows surveys of current Japanese regulations relevant to nuclear security, including regulations for nuclear damage compensation. It also shows the regulatory issues still left unresolved, particularly the question of whether existing laws are broad enough, or whether new legislation will be needed. The largest unresolved issue is how to establish a system of physical protection of nuclear materials for broader nuclear security purposes within a system that was originally introduced only to control nuclear proliferation. Such a system will necessitate a radical revision of the relevant law. Moreover, the current regulations have left unresolved the physical protection of radioactive materials used in research, medical, and non-nuclear-power-related industrial operations. Japanese legislation has already authorized an integrated Nuclear Regulatory Commission. Its mandate should include introduction of a physical protection system for currently unregulated radioactive materials. This will also necessitate a radical revision of the relevant law. Comprehensive consideration should also be given to transportation of nuclear materials away from the site of nuclear material processing businesses. Current regulation also leaves this issue unresolved. There is a possibility that consistent protective measures may not be possible across transportation modes even under the recent legislation that authorized reorganization of nuclear regulatory authorities. (author)

JOICFP included in GII mission to Ghana. Global Issues Initiative.

Science.gov (United States)

1996-03-01

Among countries in West Africa, Ghana is the main focus of the Global Issues Initiative (GII) on Population and AIDS and one of twelve priority countries selected for official development assistance (ODA) under the program. A ten-member project formulation mission sent to Ghana by the Ministry of Foreign Affairs (MOFA) of Japan was in the country during January 10-18. This mission was the first of its kind to be sent to Africa. It was led by the director of the Third Project Formulation Study Division, Project Formulation Study Department, Japan International Cooperation Agency (JICA), and included representatives of MOFA, JICA, and the Ministry of Health and Welfare, and an observer from UNAIDS. The mission's chief objective was to explore possibilities for Japanese cooperation in the areas of population, child health, and HIV/AIDS in line with the Mid-Term Health Strategy (MTHS) formulated in 1995 by the government of Ghana. The mission also explored the possibility of collaboration with major donors, international organizations, international agencies, and NGOs. The mission met with representatives of NGOs from population, women, AIDS, and health-related areas on January 13, who were then briefed upon Japan's Grant Assistance for Grassroots Project for local NGOs. Views were exchanged upon NGO activities.

The essence of turbulence as a physical phenomenon with emphasis on issues of paradigmatic nature

CERN Document Server

Tsinober, Arkady

2014-01-01

This book critically reexamines what turbulence really is, from a fundamental point of view and based on observations from nature, laboratories, and direct numerical simulations. It includes critical assessments and a comparative analysis of the key developments, their evolution and failures, along with key misconceptions and outdated paradigms. The main emphasis is on conceptual and problematic aspects, physical phenomena, observations, misconceptions and unresolved issues rather than on conventional formalistic aspects, models, etc. Apart from the obvious fundamental importance of turbulent flows, this emphasis stems from the basic premise that without corresponding progress in fundamental aspects there is little chance for progress in applications such as drag reduction, mixing, control and modeling of turbulence. More generally, there is also a desperate need to grasp the physical fundamentals of the technological processes in which turbulence plays a central role.

Regulatory Safety Issues in the Structural Design Criteria of ASME Section III Subsection NH and for Very High Temperatures for VHTR & GEN IV

Energy Technology Data Exchange (ETDEWEB)

William J. O’Donnell; Donald S. Griffin

2007-05-07

The objective of this task is to identify issues relevant to ASME Section III, Subsection NH [1], and related Code Cases that must be resolved for licensing purposes for VHTGRs (Very High Temperature Gas Reactor concepts such as those of PBMR, Areva, and GA); and to identify the material models, design criteria, and analysis methods that need to be added to the ASME Code to cover the unresolved safety issues. Subsection NH was originally developed to provide structural design criteria and limits for elevated-temperature design of Liquid Metal Fast Breeder Reactor (LMFBR) systems and some gas-cooled systems. The U.S. Nuclear Regulatory Commission (NRC) and its Advisory Committee for Reactor Safeguards (ACRS) reviewed the design limits and procedures in the process of reviewing the Clinch River Breeder Reactor (CRBR) for a construction permit in the late 1970s and early 1980s, and identified issues that needed resolution. In the years since then, the NRC and various contractors have evaluated the applicability of the ASME Code and Code Cases to high-temperature reactor designs such as the VHTGRs, and identified issues that need to be resolved to provide a regulatory basis for licensing. This Report describes: (1) NRC and ACRS safety concerns raised during the licensing process of CRBR , (2) how some of these issues are addressed by the current Subsection NH of the ASME Code; and (3) the material models, design criteria, and analysis methods that need to be added to the ASME Code and Code Cases to cover unresolved regulatory issues for very high temperature service.

Multiple system responses program: Identification of concerns related to a number of specific regulatory issues

International Nuclear Information System (INIS)

Murphy, G.A.; Casada, M.L.; Palko, L.E.; Roberts, M.W.

1989-10-01

This document describes the activities and results of the Multiple System Responses (MSR) program conducted by the Nuclear Operations Analysis Center (NOAC) at Oak Ridge National Laboratory (ORNL). The objective of the MSR program was to gather and review documentation for several unresolved safety issues and related programs of interest, and from that documentation, describe any additional potential safety concerns. The MSR program provides information that will aid the NRC staff in making an assessment of the relative safety significance of the concerns through the established prioritization process. Judgments were not made regarding the validity of the concerns expressed by others. Rather, the concerns were documented and potential safety issues were developed and defined as specifically as possible. Twenty-one potential safety issues were developed from the documented concerns. Additional information was gathered to support the NRC efforts in reviewing these issues for prioritization. 73 refs., 2 tabs

Regulatory Safety Issues in the Structural Design Criteria of ASME Section III Subsection NH and for Very High Temperatures for VHTR and GEN IV

International Nuclear Information System (INIS)

O'Donnell, William J.; Griffin, Donald S.

2007-01-01

The objective of this task is to identify issues relevant to ASME Section III, Subsection NH [1], and related Code Cases that must be resolved for licensing purposes for VHTGRs (Very High Temperature Gas Reactor concepts such as those of PBMR, Areva, and GA); and to identify the material models, design criteria, and analysis methods that need to be added to the ASME Code to cover the unresolved safety issues. Subsection NH was originally developed to provide structural design criteria and limits for elevated-temperature design of Liquid Metal Fast Breeder Reactor (LMFBR) systems and some gas-cooled systems. The U.S. Nuclear Regulatory Commission (NRC) and its Advisory Committee for Reactor Safeguards (ACRS) reviewed the design limits and procedures in the process of reviewing the Clinch River Breeder Reactor (CRBR) for a construction permit in the late 1970s and early 1980s, and identified issues that needed resolution. In the years since then, the NRC and various contractors have evaluated the applicability of the ASME Code and Code Cases to high-temperature reactor designs such as the VHTGRs, and identified issues that need to be resolved to provide a regulatory basis for licensing. This Report describes: (1) NRC and ACRS safety concerns raised during the licensing process of CRBR , (2) how some of these issues are addressed by the current Subsection NH of the ASME Code; and (3) the material models, design criteria, and analysis methods that need to be added to the ASME Code and Code Cases to cover unresolved regulatory issues for very high temperature service.

Are CSF Biomarkers Useful as Prognostic Indicators in Diagnostically Unresolved Cognitively Impaired Patients in a Normal Clinical Setting

DEFF Research Database (Denmark)

Nielsen, Malene Schjønning; Simonsen, Anja Hviid; Siersma, Volkert

2016-01-01

in diagnostically unresolved patients. METHODS: Data on 348 patients were retrospectively evaluated. All participants had a standardized diagnostic workup and follow-up in a memory clinic. RESULTS: Aβ42 levels and Aβ42/p-tau ratios were reduced and levels of t-tau and p-tau as well as the t-tau × p-tau/Aβ42 ratio...

On uncertainties and fluctuations of averaged neutron cross sections in unresolved resonance energy region for 235U, 238U, 239Pu

International Nuclear Information System (INIS)

Van'kov, A.A.; Blokhin, A.I.; Manokhin, V.N.; Kravchenko, I.V.

1985-01-01

This paper analyses the reasons for the differences which exist between group-averaged evaluated cross-section data from different evaluated data files for U235, U238 and Pu239 in the unresolved resonance energy region. (author)

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes.

Science.gov (United States)

Hu, H; Haas, S A; Chelly, J; Van Esch, H; Raynaud, M; de Brouwer, A P M; Weinert, S; Froyen, G; Frints, S G M; Laumonnier, F; Zemojtel, T; Love, M I; Richard, H; Emde, A-K; Bienek, M; Jensen, C; Hambrock, M; Fischer, U; Langnick, C; Feldkamp, M; Wissink-Lindhout, W; Lebrun, N; Castelnau, L; Rucci, J; Montjean, R; Dorseuil, O; Billuart, P; Stuhlmann, T; Shaw, M; Corbett, M A; Gardner, A; Willis-Owen, S; Tan, C; Friend, K L; Belet, S; van Roozendaal, K E P; Jimenez-Pocquet, M; Moizard, M-P; Ronce, N; Sun, R; O'Keeffe, S; Chenna, R; van Bömmel, A; Göke, J; Hackett, A; Field, M; Christie, L; Boyle, J; Haan, E; Nelson, J; Turner, G; Baynam, G; Gillessen-Kaesbach, G; Müller, U; Steinberger, D; Budny, B; Badura-Stronka, M; Latos-Bieleńska, A; Ousager, L B; Wieacker, P; Rodríguez Criado, G; Bondeson, M-L; Annerén, G; Dufke, A; Cohen, M; Van Maldergem, L; Vincent-Delorme, C; Echenne, B; Simon-Bouy, B; Kleefstra, T; Willemsen, M; Fryns, J-P; Devriendt, K; Ullmann, R; Vingron, M; Wrogemann, K; Wienker, T F; Tzschach, A; van Bokhoven, H; Gecz, J; Jentsch, T J; Chen, W; Ropers, H-H; Kalscheuer, V M

2016-01-01

X-linked intellectual disability (XLID) is a clinically and genetically heterogeneous disorder. During the past two decades in excess of 100 X-chromosome ID genes have been identified. Yet, a large number of families mapping to the X-chromosome remained unresolved suggesting that more XLID genes or loci are yet to be identified. Here, we have investigated 405 unresolved families with XLID. We employed massively parallel sequencing of all X-chromosome exons in the index males. The majority of these males were previously tested negative for copy number variations and for mutations in a subset of known XLID genes by Sanger sequencing. In total, 745 X-chromosomal genes were screened. After stringent filtering, a total of 1297 non-recurrent exonic variants remained for prioritization. Co-segregation analysis of potential clinically relevant changes revealed that 80 families (20%) carried pathogenic variants in established XLID genes. In 19 families, we detected likely causative protein truncating and missense variants in 7 novel and validated XLID genes (CLCN4, CNKSR2, FRMPD4, KLHL15, LAS1L, RLIM and USP27X) and potentially deleterious variants in 2 novel candidate XLID genes (CDK16 and TAF1). We show that the CLCN4 and CNKSR2 variants impair protein functions as indicated by electrophysiological studies and altered differentiation of cultured primary neurons from Clcn4(-/-) mice or after mRNA knock-down. The newly identified and candidate XLID proteins belong to pathways and networks with established roles in cognitive function and intellectual disability in particular. We suggest that systematic sequencing of all X-chromosomal genes in a cohort of patients with genetic evidence for X-chromosome locus involvement may resolve up to 58% of Fragile X-negative cases.

Gas kinematics in FIRE simulated galaxies compared to spatially unresolved H I observations

Science.gov (United States)

El-Badry, Kareem; Bradford, Jeremy; Quataert, Eliot; Geha, Marla; Boylan-Kolchin, Michael; Weisz, Daniel R.; Wetzel, Andrew; Hopkins, Philip F.; Chan, T. K.; Fitts, Alex; Kereš, Dušan; Faucher-Giguère, Claude-André

2018-06-01

The shape of a galaxy's spatially unresolved, globally integrated 21-cm emission line depends on its internal gas kinematics: galaxies with rotationally supported gas discs produce double-horned profiles with steep wings, while galaxies with dispersion-supported gas produce Gaussian-like profiles with sloped wings. Using mock observations of simulated galaxies from the FIRE project, we show that one can therefore constrain a galaxy's gas kinematics from its unresolved 21-cm line profile. In particular, we find that the kurtosis of the 21-cm line increases with decreasing V/σ and that this trend is robust across a wide range of masses, signal-to-noise ratios, and inclinations. We then quantify the shapes of 21-cm line profiles from a morphologically unbiased sample of ˜2000 low-redshift, H I-detected galaxies with Mstar = 107-11 M⊙ and compare to the simulated galaxies. At Mstar ≳ 1010 M⊙, both the observed and simulated galaxies produce double-horned profiles with low kurtosis and steep wings, consistent with rotationally supported discs. Both the observed and simulated line profiles become more Gaussian like (higher kurtosis and less-steep wings) at lower masses, indicating increased dispersion support. However, the simulated galaxies transition from rotational to dispersion support more strongly: at Mstar = 108-10 M⊙, most of the simulations produce more Gaussian-like profiles than typical observed galaxies with similar mass, indicating that gas in the low-mass simulated galaxies is, on average, overly dispersion supported. Most of the lower-mass-simulated galaxies also have somewhat lower gas fractions than the median of the observed population. The simulations nevertheless reproduce the observed line-width baryonic Tully-Fisher relation, which is insensitive to rotational versus dispersion support.

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the doubly unresolved subtraction terms

CERN Document Server

Somogyi, Gabor

2013-01-01

We finish the definition of a subtraction scheme for computing NNLO corrections to QCD jet cross sections. In particular, we perform the integration of the soft-type contributions to the doubly unresolved counterterms via the method of Mellin-Barnes representations. With these final ingredients in place, the definition of the scheme is complete and the computation of the regularised doubly virtual contribution to the NNLO cross section becomes feasible.

Issues concerning scientific production of including people with disabilities at work.

Science.gov (United States)

Guimarães, B M; Martins, L B; Barkokébas Junior, B

2012-01-01

This article presents the results of a survey carried out on leading periodicals in the areas of Ergonomics, Physiotherapy and Occupational Therapy, the aim of which was to identify scientific publications on the inclusion at work of people with disabilities. The survey of articles published on this topic in the following journals was conducted in December 2010: Applied Ergonomics, Ergonomics, the International Journal of Industrial Ergonomics, Disability and Rehabilitation, and the Journal of Occupational Rehabilitation. The survey covered issues published between 2000 and 2010 and was conducted electronically using the CAPES Periodicals Portal. To collect the articles, it was necessary to check the articles published in each of the issues of each volume of these periodicals. This is how the articles on the topic in question were found. There were 27 articles on the topic of inclusion at work of people with disabilities, of which 13 were published in the Journal of Occupational Rehabilitation and 12 in Disability and Rehabilitation. Thus, it is clear that the issue in question is still a subject that is seldom dealt with in these publications and it is noted that only two articles were published in Ergonomics journals in this period, thus confirming the paucity of scientific publications on this subject.

Simulation analysis of photometric data for attitude estimation of unresolved space objects

Science.gov (United States)

Du, Xiaoping; Gou, Ruixin; Liu, Hao; Hu, Heng; Wang, Yang

2017-10-01

The attitude information acquisition of unresolved space objects, such as micro-nano satellites and GEO objects under the way of ground-based optical observations, is a challenge to space surveillance. In this paper, a useful method is proposed to estimate the SO attitude state according to the simulation analysis of photometric data in different attitude states. The object shape model was established and the parameters of the BRDF model were determined, then the space object photometric model was established. Furthermore, the photometric data of space objects in different states are analyzed by simulation and the regular characteristics of the photometric curves are summarized. The simulation results show that the photometric characteristics are useful for attitude inversion in a unique way. Thus, a new idea is provided for space object identification in this paper.

Chromospheric counterparts of solar transition region unresolved fine structure loops

Science.gov (United States)

Pereira, Tiago M. D.; Rouppe van der Voort, Luc; Hansteen, Viggo H.; De Pontieu, Bart

2018-04-01

Low-lying loops have been discovered at the solar limb in transition region temperatures by the Interface Region Imaging Spectrograph (IRIS). They do not appear to reach coronal temperatures, and it has been suggested that they are the long-predicted unresolved fine structures (UFS). These loops are dynamic and believed to be visible during both heating and cooling phases. Making use of coordinated observations between IRIS and the Swedish 1-m Solar Telescope, we study how these loops impact the solar chromosphere. We show for the first time that there is indeed a chromospheric signal of these loops, seen mostly in the form of strong Doppler shifts and a conspicuous lack of chromospheric heating. In addition, we find that several instances have a inverse Y-shaped jet just above the loop, suggesting that magnetic reconnection is driving these events. Our observations add several puzzling details to the current knowledge of these newly discovered structures; this new information must be considered in theoretical models. Two movies associated to Fig. 1 are available at http://https://www.aanda.org

Causal Indicator Models: Unresolved Issues of Construction and Evaluation

Science.gov (United States)

West, Stephen G.; Grimm, Kevin J.

2014-01-01

These authors agree with Bainter and Bollen that causal effects represents a useful measurement structure in some applications. The structure of the science of the measurement problem should determine the model; the measurement model should not determine the science. They also applaud Bainter and Bollen's important reminder that the full…

Weight change and incident diabetes: addressing an unresolved issue

NARCIS (Netherlands)

Jacobs-van der Bruggen, M.A.M.; Spijkerman, A.M.W.; Baal, van P.H.M.; Baan, C.A.; Feskens, E.J.M.; Picavet, H.S.J.; A, van der A.D.; Verschuren, W.M.M.

2010-01-01

The impact of weight change on diabetes incidence remains unclear. To clarify the role of weight change as a risk factor for diabetes, the authors assessed the association between weight change and diabetes incidence conditional upon either initial or attained body mass index (BMI). They used 7,837

Enhancing regulatory effectiveness by improving the process for identifying and resolving generic issues

International Nuclear Information System (INIS)

Vander Molen, Harold J.

2001-01-01

The Generic Issues Program first began formally in response to a Commission directive in October of 1976. In 1983, it became one of the first programs to make successful use of probabilistic risk information to aid in regulatory decision-making. In the 16 years since the program became quantitative, 836 issues have been processed. Of these, 106 reactor safety issues were prioritized as requiring further evaluation to determine the final resolution. Approximately a dozen generic issues remain unresolved. Although there is far less reactor licensing activity than in the 1970s, new issues continue to be identified from research and operational experience. These issues often involve complex and controversial questions of safety and regulation, and an efficient and effective means of addressing these issues is essential for regulatory effectiveness. Issues that involve a significant safety question require swift, effective, enforceable, and cost-effective regulatory actions. Issues that are of little safety significance must be quickly shown to be so and dismissed in an expeditious manner so as to avoid unnecessary expenditure of limited resources and to reduce regulatory uncertainty. Additionally, in the time since the generic issue program began, probabilistic risk assessment techniques have advanced significantly while agency resources have continued to diminish. Accordingly, the paper discusses the steps that have been taken to enhance the effectiveness and efficiency of the generic issue resolution process. Additionally, four resolved issues are discussed, along with key elements of a proposed new procedure for resolving potential generic issues

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the doubly unresolved subtraction terms

Science.gov (United States)

Somogyi, Gábor

2013-04-01

We finish the definition of a subtraction scheme for computing NNLO corrections to QCD jet cross sections. In particular, we perform the integration of the soft-type contributions to the doubly unresolved counterterms via the method of Mellin-Barnes representations. With these final ingredients in place, the definition of the scheme is complete and the computation of fully differential rates for electron-positron annihilation into two and three jets at NNLO accuracy becomes feasible.

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the doubly unresolved subtraction terms

OpenAIRE

Somogyi, Gabor

2013-01-01

We finish the definition of a subtraction scheme for computing NNLO corrections to QCD jet cross sections. In particular, we perform the integration of the soft-type contributions to the doubly unresolved counterterms via the method of Mellin-Barnes representations. With these final ingredients in place, the definition of the scheme is complete and the computation of fully differential rates for electron-positron annihilation into two and three jets at NNLO accuracy becomes feasible.

Contribution of resolved and unresolved harmonic regions to brainstem speech-evoked responses in quiet and in background noise

Directory of Open Access Journals (Sweden)

M. Laroche

2011-03-01

Full Text Available Speech auditory brainstem responses (speech ABR reflect activity that is phase-locked to the harmonics of the fundamental frequency (F0 up to at least the first formant (F1. Recent evidence suggests that responses at F0 in the presence of noise are more robust than responses at F1, and are also dissociated in some learning-impaired children. Peripheral auditory processing can be broadly divided into resolved and unresolved harmonic regions. This study investigates the contribution of these two regions to the speech ABR, and their susceptibility to noise. We recorded, in quiet and in background white noise, evoked responses in twelve normal hearing adults in response to three variants of a synthetic vowel: i Allformants, which contains all first three formants, ii F1Only, which is dominated by resolved harmonics, and iii F2&F3Only, which is dominated by unresolved harmonics. There were no statistically significant differences in the response at F0 due to the three variants of the stimulus in quiet, nor did the noise affect this response with the Allformants and F1Only variants. On the other hand, the response at F0 with the F2&F3Only variant was significantly weaker in noise than with the two other variants (p<0.001. With the response at F1, there was no difference with the Allformants and F1Only variants in quiet, but was expectedly weaker with the F2&F3Only variant (p<0.01. The addition of noise significantly weakened the response at F1 with the F1Only variant (p<0.05, but this weakening only tended towards significance with the Allformants variant (p=0.07. The results of this study indicate that resolved and unresolved harmonics are processed in different but interacting pathways that converge in the upper brainstem. The results also support earlier work on the differential susceptibility of responses at F0 and F1 to added noise.

Unresolved issues in theories of autoimmune disease using myocarditis as a framework.

Science.gov (United States)

Root-Bernstein, Robert; Fairweather, DeLisa

2015-06-21

Many theories of autoimmune disease have been proposed since the discovery that the immune system can attack the body. These theories include the hidden or cryptic antigen theory, modified antigen theory, T cell bypass, T cell-B cell mismatch, epitope spread or drift, the bystander effect, molecular mimicry, anti-idiotype theory, antigenic complementarity, and dual-affinity T cell receptors. We critically review these theories and relevant mathematical models as they apply to autoimmune myocarditis. All theories share the common assumption that autoimmune diseases are triggered by environmental factors such as infections or chemical exposure. Most, but not all, theories and mathematical models are unifactorial assuming single-agent causation of disease. Experimental and clinical evidence and mathematical models exist to support some aspects of most theories, but evidence/models that support one theory almost invariably supports other theories as well. More importantly, every theory (and every model) lacks the ability to account for some key autoimmune disease phenomena such as the fundamental roles of innate immunity, sex differences in disease susceptibility, the necessity for adjuvants in experimental animal models, and the often paradoxical effect of exposure timing and dose on disease induction. We argue that a more comprehensive and integrated theory of autoimmunity associated with new mathematical models is needed and suggest specific experimental and clinical tests for each major theory that might help to clarify how they relate to clinical disease and reveal how theories are related. Copyright © 2014 Elsevier Ltd. All rights reserved.

Unresolved issues in theories of autoimmune disease using myocarditis as a framework

Science.gov (United States)

Root-Bernstein, Robert; Fairweather, DeLisa

2014-01-01

Many theories of autoimmune disease have been proposed since the discovery that the immune system can attack the body. These theories include the hidden or cryptic antigen theory, modified antigen theory, T cell bypass, T cell-B cell mismatch, epitope spread or drift, the bystander effect, molecular mimicry, anti-idiotype theory, antigenic complementarity, and dual-affinity T cell receptors. We critically review these theories and relevant mathematical models as they apply to autoimmune myocarditis. All theories share the common assumption that autoimmune diseases are triggered by environmental factors such as infections or chemical exposure. Most, but not all, theories and mathematical models are unifactorial assuming single-agent causation of disease. Experimental and clinical evidence and mathematical models exist to support some aspects of most theories, but evidence/models that support one theory almost invariably supports other theories as well. More importantly, every theory (and every model) lacks the ability to account for some key autoimmune disease phenomena such as the fundamental roles of innate immunity, sex differences in disease susceptibility, the necessity for adjuvants in experimental animal models, and the often paradoxical effect of exposure timing and dose on disease induction. We argue that a more comprehensive and integrated theory of autoimmunity associated with new mathematical models is needed and suggest specific experimental and clinical tests for each major theory that might help to clarify how they relate to clinical disease and reveal how theories are related. PMID:25484004

End of FY2014 Report - Filter Measurement System for Nuclear Material Storage Canisters (Including Altitude Correction for Filter Pressure Drop)

Energy Technology Data Exchange (ETDEWEB)

Moore, Murray E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reeves, Kirk Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-02-24

Two LANL FTS (Filter Test System ) devices for nuclear material storage canisters are fully operational. One is located in PF-4 ( i.e. the TA-55 FTS) while the other is located at the Radiation Protection Division’s Aerosol Engineering Facility ( i.e. the TA-3 FTS). The systems are functionally equivalent , with the TA-3 FTS being the test-bed for new additions and for resolving any issues found in the TA-55 FTS. There is currently one unresolved issue regarding the TA-55 FTS device. The canister lid clamp does not give a leak tight seal when testing the 1 QT (quart) or 2 QT SAVY lids. An adapter plate is being developed that will ensure a correct test configuration when the 1 or 2 QT SAVY lid s are being tested .

Towards an Effective Management Strategy for Passive RFID Implementation

National Research Council Canada - National Science Library

Fisch, John N; Koch, David M

2004-01-01

.... However, many issues central to passive RFID implementation remain unresolved. First and foremost, a comprehensive management strategy, including a complete redesign of business practices, must be developed...

Physician Perspectives on Unresolved Issues in the Management of Ulcerative Colitis: The UC Horizons Project.

Science.gov (United States)

Gisbert, Javier P; Barreiro-de Acosta, Manuel; Esteve, María; García-Sánchez, Valle; Gomollón, Fernando; Guardiola, Jordi; Hinojosa, Joaquin; Martín Arranz, Maria-Dolores; Minguez, Miguel; Taxonera, Carlos; Vera, Isabel

2016-03-01

There is still uncertainty about what constitutes the best therapeutic practice in ulcerative colitis (UC). The purpose of the "UC Horizons Project" was to raise a series of questions regarding the management of UC to provide responses based on the best scientific evidence available. The 11 members of the scientific committee prepared draft answers to the 10 questions from available evidence after a literature search. A total of 48 Spanish gastroenterology specialists nationwide participated in the project. The national meeting discussed the 10 issues in working groups and reached consensus regarding the recommendations by anonymous, interactive vote following the Delphi methodology. Final answers were developed, based on evidence and clinical experience of the participants. All the recommendations achieved a high level of agreement in the plenary vote, although the quality of the evidence was markedly heterogeneous. The lowest percentage of agreement corresponded to the questions with the weakest level of evidence, highlighting the necessity of conducting further studies in these areas. The recommendations focused on (1) aminosalicylates therapy (regarding dose and appropriateness of coadministration with thiopurines), (2) corticosteroid therapy (regarding dose and route of administration), (3) thiopurine treatment (regarding indications and possibility of withdrawal), (4) anti-tumor necrosis factor therapy (regarding appropriateness of combination with thiopurines, intensification, or discontinuation of treatment), and (5) colorectal cancer (regarding risk and time trends). The UC Horizons Project raised a series of eminently practical questions about the management of UC and provided responses based on the best scientific evidence available.

A case of woman abuse: gender ideologies, power paradoxes, and unresolved conflict.

Science.gov (United States)

Rosen, K H; Bird, K

1996-09-01

This paper describes some of the complex individual and relationship processes that occurred in an intimate relationship where love and violence coexisted. It presents a longitudinal, qualitative study of a premarital relationship in which the man had been repeatedly violent towards his female partner. It describes how gender role ideologies, the distribution of power between partners, and unresolved conflict are related to each other and to the emergence of violence and maintenance of couple bonds. A grounded theory approach was used to collect and analyze data for this single case and qualitative study in which both partners were interviewed several times each over the course of 1.5 years. Overall, it was found that intimate relationships that become contexts for expressions of love and violence are indeed complex, and the flexibility to consider the complexities that are involved provide a context for developing creative solutions.

Position statement--altitude training for improving team-sport players' performance: current knowledge and unresolved issues.

Science.gov (United States)

Girard, Olivier; Amann, Markus; Aughey, Robert; Billaut, François; Bishop, David J; Bourdon, Pitre; Buchheit, Martin; Chapman, Robert; D'Hooghe, Michel; Garvican-Lewis, Laura A; Gore, Christopher J; Millet, Grégoire P; Roach, Gregory D; Sargent, Charli; Saunders, Philo U; Schmidt, Walter; Schumacher, Yorck O

2013-12-01

Despite the limited research on the effects of altitude (or hypoxic) training interventions on team-sport performance, players from all around the world engaged in these sports are now using altitude training more than ever before. In March 2013, an Altitude Training and Team Sports conference was held in Doha, Qatar, to establish a forum of research and practical insights into this rapidly growing field. A round-table meeting in which the panellists engaged in focused discussions concluded this conference. This has resulted in the present position statement, designed to highlight some key issues raised during the debates and to integrate the ideas into a shared conceptual framework. The present signposting document has been developed for use by support teams (coaches, performance scientists, physicians, strength and conditioning staff) and other professionals who have an interest in the practical application of altitude training for team sports. After more than four decades of research, there is still no consensus on the optimal strategies to elicit the best results from altitude training in a team-sport population. However, there are some recommended strategies discussed in this position statement to adopt for improving the acclimatisation process when training/competing at altitude and for potentially enhancing sea-level performance. It is our hope that this information will be intriguing, balanced and, more importantly, stimulating to the point that it promotes constructive discussion and serves as a guide for future research aimed at advancing the bourgeoning body of knowledge in the area of altitude training for team sports.

Position statement—altitude training for improving team-sport players’ performance: current knowledge and unresolved issues

Science.gov (United States)

Girard, Olivier; Amann, Markus; Aughey, Robert; Billaut, François; Bishop, David J; Bourdon, Pitre; Buchheit, Martin; Chapman, Robert; D'Hooghe, Michel; Garvican-Lewis, Laura A; Gore, Christopher J; Millet, Grégoire P; Roach, Gregory D; Sargent, Charli; Saunders, Philo U; Schmidt, Walter; Schumacher, Yorck O

2013-01-01

Despite the limited research on the effects of altitude (or hypoxic) training interventions on team-sport performance, players from all around the world engaged in these sports are now using altitude training more than ever before. In March 2013, an Altitude Training and Team Sports conference was held in Doha, Qatar, to establish a forum of research and practical insights into this rapidly growing field. A round-table meeting in which the panellists engaged in focused discussions concluded this conference. This has resulted in the present position statement, designed to highlight some key issues raised during the debates and to integrate the ideas into a shared conceptual framework. The present signposting document has been developed for use by support teams (coaches, performance scientists, physicians, strength and conditioning staff) and other professionals who have an interest in the practical application of altitude training for team sports. After more than four decades of research, there is still no consensus on the optimal strategies to elicit the best results from altitude training in a team-sport population. However, there are some recommended strategies discussed in this position statement to adopt for improving the acclimatisation process when training/competing at altitude and for potentially enhancing sea-level performance. It is our hope that this information will be intriguing, balanced and, more importantly, stimulating to the point that it promotes constructive discussion and serves as a guide for future research aimed at advancing the bourgeoning body of knowledge in the area of altitude training for team sports. PMID:24282213

Recommendations for resolution of public comments on USI [Unresolved Safety Issues] A-40, ''Seismic Design Criteria''

International Nuclear Information System (INIS)

Philippacopoulos, A.J.

1989-06-01

In June 1988 the Nuclear Regulatory Commission (NRC) issued for public comment the proposed Revision 2 of the Standard Review Plan (SRP) Sections 2.5.2, 3.7.1, 3.7.2. and 3.7.3. Comments were received from six organizations. Brookhaven National Laboratory (BNL) was requested by NRC to provide expert consultation in the seismic and soil-structure interaction areas for the review and resolution of these comments. For this purpose, a panel of consultants was established to assist BNL with the review and evaluation of the public comments. This review was carried out during the period of October 1988 through January 1989. Many of the suggestions given in the public comments were found to be significant and a number of modifications to appropriate SRP sections are recommended. Other public comments were found to have no impact on the proposed Revision 2 of the SRP. Major changes are recommended to the SRP sections dealing with (a) Power Spectral Density (PSD) and ground motion requirements and (b) soil-structure interaction requirements. This report contains specific recommendations to NRC for resolution of the public comments made on the proposed Revision 2 of the SRP

Results of arthroscopic treatment in unresolved Osgood-Schlatter disease in athletes.

Science.gov (United States)

Circi, Esra; Beyzadeoglu, Tahsin

2017-02-01

In this study we aimed to determine outcomes following arthroscopic ossicle excision in athletes with unresolved Osgood-Schlatter disease (OSD). Arthroscopy was performed on 11 patients (11 knees) with OSD between September 2008 and November 2014. Surgical treatment inclusion criteria were determined as: failure of conservative treatment; isolated pain over the tibial tubercle and distal patellar tendon; pain limiting sporting performance at a competitive level. All patients had a documented history of OSD; the mean duration of persistent pain over the tibial tubercle was 15.5 months. The mean age was 23 years. The mean follow-up period was 66.1 months. The mean latency in returning to sports related training activities after the surgery was 6.7 weeks. The mean Kujala patello-femoral score improved from 82.9 points pre-operatively, to 98.5 points at the final follow-up (p operative period, increasing to a score of 96.9 points at final follow-up (p operative period, increasing to 8.5 post-operatively (p advantage of faster recovery and avoiding damage to the patellar tendon.

Optimisation of chromatographic resolution using objective functions including both time and spectral information.

Science.gov (United States)

Torres-Lapasió, J R; Pous-Torres, S; Ortiz-Bolsico, C; García-Alvarez-Coque, M C

2015-01-16

The optimisation of the resolution in high-performance liquid chromatography is traditionally performed attending only to the time information. However, even in the optimal conditions, some peak pairs may remain unresolved. Such incomplete resolution can be still accomplished by deconvolution, which can be carried out with more guarantees of success by including spectral information. In this work, two-way chromatographic objective functions (COFs) that incorporate both time and spectral information were tested, based on the peak purity (analyte peak fraction free of overlapping) and the multivariate selectivity (figure of merit derived from the net analyte signal) concepts. These COFs are sensitive to situations where the components that coelute in a mixture show some spectral differences. Therefore, they are useful to find out experimental conditions where the spectrochromatograms can be recovered by deconvolution. Two-way multivariate selectivity yielded the best performance and was applied to the separation using diode-array detection of a mixture of 25 phenolic compounds, which remained unresolved in the chromatographic order using linear and multi-linear gradients of acetonitrile-water. Peak deconvolution was carried out using the combination of orthogonal projection approach and alternating least squares. Copyright © 2014 Elsevier B.V. All rights reserved.

Multiple Personalities: Childhood Unresolved Conflicts and Trauma In Clark’s All Around The Town

Directory of Open Access Journals (Sweden)

Fatma Hetami

2011-06-01

Full Text Available This paper is aimed at describing how multiple personalities as the unresolved childhood conflict and trauma are revealed in Clark’s All Around the Town. The novel is analyzed by using psychological approach. It is based on the assumption that any work of literature always deals with human life in terms of his personality structure and psychological condition. The results indicate that as a character, Laurie Kenyon is around and developing. It can be seen from her various traits. In one, she is smart and sweet. But on the other hand, she is anxious and gets afraid easily. As an individual, Laurie’s Id is weak. Her Super-ego, which appears as forms of traumatic experience and unresolved childhood conflict, are embedded strongly in Laurie’s personality. Therefore, she tries to create her ego in the form of multiple personalities to help her out of her problems. Abstrak: Tulisan ini merupakan hasil penelitian yang bertujuan untuk mendeskripsikan bagaimana kepribadian ganda sebagai akibat trauma dan konflik masa kecil yang tidak teratasi muncul pada novel All Around the Town Karya Marry Higgins Clark. Novel ini dianalisis dengan menggunakan pendekatan psikologi sastra. Hal tersebut didasarkan pada asumsi bahwa semua karya sastra selalu berhubungan dengan kehidupan manusia khususnya kepribadian dan kondisi psikologis. Hasil analisis menunjukkan bahwa sebagai tokoh, Laurie Kenyon memiliki karakter bulat dan dinamis. Hal ini bisa dilihat dari sifat-sifat yang dimilikinya serta bagaimana kepribadian Laurie berubah dari awal sampai akhir cerita. Di satu sisi Laurie merupakan gadis yang cerdas dan manis. Namun di lain sisi, ia juga pencemas dan penakut. Sebagai individu, Laurie memiliki id yang lemah. Super ego berupa pengalaman trauma dan konflik yang tidak teratasi semasa kecil terlalu kuat tertanam dalam diri Laurie, sehingga ia berusaha menciptak an ego dalam bentuk kepribadian ganda untuk membantunya lepas dari masalah yang dihadapinya. Kata

Unmasking the hidden NGTS-3Ab: a hot Jupiter in an unresolved binary system

Science.gov (United States)

Günther, Maximilian N.; Queloz, Didier; Gillen, Edward; Delrez, Laetitia; Bouchy, François; McCormac, James; Smalley, Barry; Almleaky, Yaseen; Armstrong, David J.; Bayliss, Daniel; Burdanov, Artem; Burleigh, Matthew; Cabrera, Juan; Casewell, Sarah L.; Cooke, Benjamin F.; Csizmadia, Szilárd; Ducrot, Elsa; Eigmüller, Philipp; Erikson, Anders; Gänsicke, Boris T.; Gibson, Neale P.; Gillon, Michaël; Goad, Michael R.; Jehin, Emmanuël; Jenkins, James S.; Louden, Tom; Moyano, Maximiliano; Murray, Catriona; Pollacco, Don; Poppenhaeger, Katja; Rauer, Heike; Raynard, Liam; Smith, Alexis M. S.; Sohy, Sandrine; Thompson, Samantha J.; Udry, Stéphane; Watson, Christopher A.; West, Richard G.; Wheatley, Peter J.

2018-05-01

We present the discovery of NGTS-3Ab, a hot Jupiter found transiting the primary star of an unresolved binary system. We develop a joint analysis of multi-colour photometry, centroids, radial velocity (RV) cross-correlation function (CCF) profiles and their bisector inverse slopes (BIS) to disentangle this three-body system. Data from the Next Generation Transit Survey (NGTS), SPECULOOS and HARPS are analysed and modelled with our new BLENDFITTER software. We find that the binary consists of NGTS-3A (G6V-dwarf) and NGTS-3B (K1V-dwarf) at 5") and are prone to contamination by blended objects. With TESS on the horizon, it is pivotal for the candidate vetting to incorporate all available follow-up information from multi-colour photometry and RV CCF profiles.

Sexual Harassment: A problem unresolved!

OpenAIRE

N Vanishree; V Chaithra; Amandeep Pabbla

2013-01-01

Sexual harassment is a highly prevalent form of gender-based discrimination and sexual exploitation in the workplace and academic environment. In the dental field, there are a few studies regarding sexual harassment among the patients, professors and claims of their students. There is a silence of consent surrounding sexual harassment. It is clearly an issue about which the practicing dentists need to be informed in order to provide knowledgeable assessment and treatment for all patients. Den...

Oxidative stress and life histories : Unresolved issues and current needs

NARCIS (Netherlands)

Speakman, John R.; Blount, Jonathan D.; Bronikowski, Anne M.; Buffenstein, Rochelle; Isaksson, Caroline; Kirkwood, Tom B. L.; Monaghan, Pat; Ozanne, Susan E.; Beaulieu, Michael; Briga, Michael; Carr, Sarah K.; Christensen, Louise L.; Cocheme, Helena M.; Cram, Dominic L.; Dantzer, Ben; Harper, Jim M.; Jurk, Diana; King, Annette; Noguera, Jose C.; Salin, Karine; Sild, Elin; Simons, Mirre J. P.; Smith, Shona; Stier, Antoine; Tobler, Michael; Vitikainen, Emma; Peaker, Malcolm; Selman, Colin

2015-01-01

Life-history theory concerns the trade-offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life-history trade-offs, but the details remain obscure. As life-history theory concerns

Oxidative stress and life histories: unresolved issues and current needs

OpenAIRE

Speakman, John R.; Blount, Jonathan D.; Bronikowski, Anne M.; Buffenstein, Rochelle; Isaksson, Caroline; Kirkwood, Tom B. L.; Monaghan, Pat; Ozanne, Susan E.; Beaulieu, Micha?l; Briga, Michael; Carr, Sarah K.; Christensen, Louise L.; Cochem?, Helena M.; Cram, Dominic L.; Dantzer, Ben

2015-01-01

Abstract Life?history theory concerns the trade?offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life?history trade?offs, but the details remain obscure. As life?history theory concerns aspects of investment in the soma that influence survival, understanding the physiological basis of life histories is related, but not identical, to understanding the process of aging. One i...

[Bioethics in end-of-life decisions in neonatology: Unresolved issues].

Science.gov (United States)

Arnaez, Juan; Tejedor, Juan Carlos; Caserío, Sonia; Montes, María Teresa; Moral, María Teresa; González de Dios, Javier; García-Alix, Alfredo

2017-12-01

This document is the result of previous work carried out by different expert groups and submitted to multidisciplinary debate at a Conference about controversial, deficient, or new aspects in the field of neonatal palliative care, such as: 1) the deliberative decision-making process, 2) hospital and domiciliary palliative care, 3) donation after controlled cardiac death, and 4) moral stress in professionals. The most relevant conclusions were: the need to instruct professionals in bioethics and in the deliberative method to facilitate thorough and reasonable decision-making; the lack of development in the field of perinatal palliative care and domiciliary palliative care in hospitals that attend newborns; the need to provide neonatal units with resources that help train professionals in communication skills and in the management of moral distress, as well as delineate operational procedure and guidelines for neonatal organ donation. Copyright © 2017 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

A review on the current issues and barriers of Industrialised Building System (IBS) adoption in Malaysia’s construction industry

Science.gov (United States)

Amin, M. A. Mohd; Abas, N. H.; Shahidan, S.; Rahmat, M. H.; Suhaini, N. A.; Nagapan, S.; Rahim, R. Abdul

2017-11-01

Malaysia considers the construction industry as one of the main contributors to its Gross Domestic Product (GDP). However, there are some unresolved issues arising from the ongoing and widespread adoption of the conventional method of construction such as the resultant fragmentation of the industry itself; delays in production and delivery time of unnecessary wastages and lack of sustainability practice. Malaysian Government has been continuously encouraging the industry to use, partly or if not wholly, the Industrialized Building System (IBS), which is considered to be an important part of sustainable construction initiative. IBS was introduced to Malaysia as the solution to issues related to dependencies of foreign workers, raising demand for affordable accommodations and improving image, quality and productivity of construction industry. However, the IBS adoption in Malaysia remains low. This paper presents the review of the current issues and barriers of IBS adoption in Malaysian construction industry.

A decade of e-cigarettes: Limited research & unresolved safety concerns.

Science.gov (United States)

Kaisar, Mohammad Abul; Prasad, Shikha; Liles, Tylor; Cucullo, Luca

2016-07-15

It is well known that tobacco consumption is a leading cause of preventable deaths worldwide and has been linked to major diseases ranging from cancer to chronic obstructive pulmonary disease, atherosclerosis, stroke and a host of neurological/neurodegenerative disorders. In the past decade a number of alternative vaping products have hit the market, rapidly gaining consumers especially among the younger population. Electronic nicotine delivery systems or e-cigarettes have become the sought-after product due to the belief that they are much safer than traditional cigarettes. However, inadequate research and lack of regulatory guidelines for both the manufacturing process and the content of the vaping solution of the e-cigarette has become a major concern. Highly debated and unresolved questions such as whether e-cigarettes may help smokers quit and whether e-cigarettes will promote the use of nicotine among non-smokers add to the confusion of the safety of e-cigarettes. In this review article, we summarize the current understanding (and lack thereof) of the potential health impacts of e-cigarettes. We will also highlight the most recent studies (in vivo/in vitro) which seem to conflict with the broad safety claims put forward by the manufacturers. Finally, we provide potential solutions to overcome the research gap of the short and long-term health impact of e-cigarettes. Published by Elsevier Ireland Ltd.

A decade of e-cigarettes: Limited research & unresolved safety concerns

International Nuclear Information System (INIS)

Kaisar, Mohammad Abul; Prasad, Shikha; Liles, Tylor; Cucullo, Luca

2016-01-01

It is well known that tobacco consumption is a leading cause of preventable deaths worldwide and has been linked to major diseases ranging from cancer to chronic obstructive pulmonary disease, atherosclerosis, stroke and a host of neurological/neurodegenerative disorders. In the past decade a number of alternative vaping products have hit the market, rapidly gaining consumers especially among the younger population. Electronic nicotine delivery systems or e-cigarettes have become the sought-after product due to the belief that they are much safer than traditional cigarettes. However, inadequate research and lack of regulatory guidelines for both the manufacturing process and the content of the vaping solution of the e-cigarette has become a major concern. Highly debated and unresolved questions such as whether e-cigarettes may help smokers quit and whether e-cigarettes will promote the use of nicotine among non-smokers add to the confusion of the safety of e-cigarettes. In this review article, we summarize the current understanding (and lack thereof) of the potential health impacts of e-cigarettes. We will also highlight the most recent studies (in vivo/in vitro) which seem to conflict with the broad safety claims put forward by the manufacturers. Finally, we provide potential solutions to overcome the research gap of the short and long-term health impact of e-cigarettes.

A Decade of e-Cigarettes: Limited Research & Unresolved Safety Concerns

Science.gov (United States)

Kaisar, Mohammad Abul; Prasad, Shikha; Liles, Tylor; Cucullo, Luca

2016-01-01

It is well known that tobacco consumption is a leading cause of preventable deaths worldwide and has been linked to major diseases ranging from cancer to chronic obstructive pulmonary disease, atherosclerosis, stroke and a host of neurological/neurodegenerative disorders. In the past decade a number of alternative vaping products have hit the market, rapidly gaining consumers especially among the younger population. Electronic nicotine delivery systems or e-cigarettes have become the sought-after product due to the belief that they are much safer than traditional cigarettes. However, inadequate research and lack of regulatory guidelines for both the manufacturing process and the content of the vaping solution of the e-cigarette has become a major concern. Highly debated and unresolved questions such as whether e-cigarettes may help smokers quit and whether e-cigarettes will promote the use of nicotine among non-smokers add to the confusion of the safety of e-cigarettes. In this review article, we summarize the current understanding (and lack thereof) of the potential health impacts of e-cigarettes. We will also highlight the most recent studies (in vivo/in vitro) which seem to conflict with the broad safety claims put forward by the manufacturers. Finally, we provide potential solutions to overcome the research gap of the short and long-term health impact of e-cigarettes. PMID:27477296

Unresolved spectral structures emitted from heavy atom plasmas produced by short pulse laser

International Nuclear Information System (INIS)

Fraenkel, M.; Zigler, A.

1999-01-01

Spectra of rare earth elements emitted from ultra short pulse laser produced plasma were recorded using simultaneously high and low resolution, spectrometers. A study of the broad band emission of the Δn = 1 transitions in highly ionized Ba and Sm plasma showed that this band is completely unresolved. The spectra were analyzed using the LTE based on super-transition array (STA) model. The theory reconstructs the entire Ba spectrum using a single temperature and density, whereas for Sm the discrepancies between the theory and experiment are not reconcilable. The agreement in the Ba case is attributed to the fact that BaF 2 target is transparent to the laser's prepulse effects, producing a homogeneous dense plasma, whereas for Sm the dilute plasma created by the prepulse is far from LTE. The obtained results posses a significant implication to the applicability of the STA model, in particular for calculations of opacities and conversion of laser light to X-rays. (orig.)

Unresolved spectral structures emitted from heavy atom plasmas produced by short pulse laser

Energy Technology Data Exchange (ETDEWEB)

Fraenkel, M.; Zigler, A. [Hebrew Univ., Jerusalem (Israel). Racah Inst. of Physics; Bar-Shalom, A.; Oreg, J. [Israel Atomic Energy Commission, Beersheba (Israel). Nuclear Research Center-Negev; Faenov, A.Ya.; Pikuz, T.A. [Multicharged Ions Spectra Data Center of VNIIFTRI, Russian Committee of Standards Moscow region (Russian Federation)

1999-09-01

Spectra of rare earth elements emitted from ultra short pulse laser produced plasma were recorded using simultaneously high and low resolution, spectrometers. A study of the broad band emission of the {delta}n = 1 transitions in highly ionized Ba and Sm plasma showed that this band is completely unresolved. The spectra were analyzed using the LTE based on super-transition array (STA) model. The theory reconstructs the entire Ba spectrum using a single temperature and density, whereas for Sm the discrepancies between the theory and experiment are not reconcilable. The agreement in the Ba case is attributed to the fact that BaF{sub 2} target is transparent to the laser's prepulse effects, producing a homogeneous dense plasma, whereas for Sm the dilute plasma created by the prepulse is far from LTE. The obtained results posses a significant implication to the applicability of the STA model, in particular for calculations of opacities and conversion of laser light to X-rays. (orig.)

Calculation of self-shielding factors for cross-sections in the unresolved resonance region using the GRUCON applied program package

International Nuclear Information System (INIS)

Sinitsa, V.V.

1984-11-01

The author gives a scheme for the calculation of the self-shielding factors in the unresolved resonance region using the GRUCON applied program package. This package is especially created to be used in the conversion of evaluated neutron cross-section data, as available in existing data libraries, into multigroup microscopic constants. A detailed description of the formulae and algorithms used in the programs is given. Some typical examples of calculation are considered and the results are compared with those of other authors. The calculation accuracy is better than 2%

Brain Networks for Working Memory and Factors of Intelligence Assessed in Males and Females with fMRI and DTI

Science.gov (United States)

Tang, C. Y.; Eaves, E. L.; Ng, J. C.; Carpenter, D. M.; Mai, X.; Schroeder, D. H.; Condon, C. A.; Colom, R.; Haier, R. J.

2010-01-01

Neuro-imaging studies of intelligence implicate the importance of a parietal-frontal network. One unresolved issue is whether this network underlies a general factor of intelligence ("g") or other specific cognitive factors. A second unresolved issue is whether males and females use different parts of this network. Here we obtained intelligence…

Survey on Security Issues in Cloud Computing and Associated Mitigation Techniques

Science.gov (United States)

Bhadauria, Rohit; Sanyal, Sugata

2012-06-01

Cloud Computing holds the potential to eliminate the requirements for setting up of high-cost computing infrastructure for IT-based solutions and services that the industry uses. It promises to provide a flexible IT architecture, accessible through internet for lightweight portable devices. This would allow multi-fold increase in the capacity or capabilities of the existing and new software. In a cloud computing environment, the entire data reside over a set of networked resources, enabling the data to be accessed through virtual machines. Since these data-centers may lie in any corner of the world beyond the reach and control of users, there are multifarious security and privacy challenges that need to be understood and taken care of. Also, one can never deny the possibility of a server breakdown that has been witnessed, rather quite often in the recent times. There are various issues that need to be dealt with respect to security and privacy in a cloud computing scenario. This extensive survey paper aims to elaborate and analyze the numerous unresolved issues threatening the cloud computing adoption and diffusion affecting the various stake-holders linked to it.

THE SPITZER INFRARED SPECTROGRAPH DEBRIS DISK CATALOG. I. CONTINUUM ANALYSIS OF UNRESOLVED TARGETS

Energy Technology Data Exchange (ETDEWEB)

Chen, Christine H. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Mittal, Tushar [Department of Earth and Planetary Science, University of California Berkeley, Berkeley, CA 94720-4767 (United States); Kuchner, Marc [NASA Goddard Space Flight Center, Exoplanets and Stellar Astrophysics Laboratory, Code 667, Greenbelt, MD 20771 (United States); Forrest, William J.; Watson, Dan M. [Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627 (United States); Lisse, Carey M. [Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723 (United States); Manoj, P. [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005 (India); Sargent, Benjamin A., E-mail: cchen@stsci.edu [Center for Imaging Science and Laboratory for Multiwavelength Astrophysics, Rochester Institute of Technology, 54 Lomb Memorial Drive, Rochester, NY 14623 (United States)

2014-04-01

During the Spitzer Space Telescope cryogenic mission, Guaranteed Time Observers, Legacy Teams, and General Observers obtained Infrared Spectrograph (IRS) observations of hundreds of debris disk candidates. We calibrated the spectra of 571 candidates, including 64 new IRAS and Multiband Imaging Photometer for Spitzer (MIPS) debris disks candidates, modeled their stellar photospheres, and produced a catalog of excess spectra for unresolved debris disks. For 499 targets with IRS excess but without strong spectral features (and a subset of 420 targets with additional MIPS 70 μm observations), we modeled the IRS (and MIPS data) assuming that the dust thermal emission was well-described using either a one- or two-temperature blackbody model. We calculated the probability for each model and computed the average probability to select among models. We found that the spectral energy distributions for the majority of objects (∼66%) were better described using a two-temperature model with warm (T {sub gr} ∼ 100-500 K) and cold (T {sub gr} ∼ 50-150 K) dust populations analogous to zodiacal and Kuiper Belt dust, suggesting that planetary systems are common in debris disks and zodiacal dust is common around host stars with ages up to ∼1 Gyr. We found that younger stars generally have disks with larger fractional infrared luminosities and higher grain temperatures and that higher-mass stars have disks with higher grain temperatures. We show that the increasing distance of dust around debris disks is inconsistent with self-stirred disk models, expected if these systems possess planets at 30-150 AU. Finally, we illustrate how observations of debris disks may be used to constrain the radial dependence of material in the minimum mass solar nebula.

Effects of mixing on resolved and unresolved scales on stratospheric age of air

Directory of Open Access Journals (Sweden)

S. Dietmüller

2017-06-01

Full Text Available Mean age of air (AoA is a widely used metric to describe the transport along the Brewer–Dobson circulation. We seek to untangle the effects of different processes on the simulation of AoA, using the chemistry–climate model EMAC (ECHAM/MESSy Atmospheric Chemistry and the Chemical Lagrangian Model of the Stratosphere (CLaMS. Here, the effects of residual transport and two-way mixing on AoA are calculated. To do so, we calculate the residual circulation transit time (RCTT. The difference of AoA and RCTT is defined as aging by mixing. However, as diffusion is also included in this difference, we further use a method to directly calculate aging by mixing on resolved scales. Comparing these two methods of calculating aging by mixing allows for separating the effect of unresolved aging by mixing (which we term aging by diffusion in the following in EMAC and CLaMS. We find that diffusion impacts AoA by making air older, but its contribution plays a minor role (order of 10 % in all simulations. However, due to the different advection schemes of the two models, aging by diffusion has a larger effect on AoA and mixing efficiency in EMAC, compared to CLaMS. Regarding the trends in AoA, in CLaMS the AoA trend is negative throughout the stratosphere except in the Northern Hemisphere middle stratosphere, consistent with observations. This slight positive trend is neither reproduced in a free-running nor in a nudged simulation with EMAC – in both simulations the AoA trend is negative throughout the stratosphere. Trends in AoA are mainly driven by the contributions of RCTT and aging by mixing, whereas the contribution of aging by diffusion plays a minor role.

An analytic approach to probability tables for the unresolved resonance region

Science.gov (United States)

Brown, David; Kawano, Toshihiko

2017-09-01

The Unresolved Resonance Region (URR) connects the fast neutron region with the Resolved Resonance Region (RRR). The URR is problematic since resonances are not resolvable experimentally yet the fluctuations in the neutron cross sections play a discernible and technologically important role: the URR in a typical nucleus is in the 100 keV - 2 MeV window where the typical fission spectrum peaks. The URR also represents the transition between R-matrix theory used to described isolated resonances and Hauser-Feshbach theory which accurately describes the average cross sections. In practice, only average or systematic features of the resonances in the URR are known and are tabulated in evaluations in a nuclear data library such as ENDF/B-VII.1. Codes such as AMPX and NJOY can compute the probability distribution of the cross section in the URR under some assumptions using Monte Carlo realizations of sets of resonances. These probability distributions are stored in the so-called PURR tables. In our work, we begin to develop a scheme for computing the covariance of the cross section probability distribution analytically. Our approach offers the possibility of defining the limits of applicability of Hauser-Feshbach theory and suggests a way to calculate PURR tables directly from systematics for nuclei whose RRR is unknown, provided one makes appropriate assumptions about the shape of the cross section probability distribution.

A precision medicine approach to a patient with unresolved pain following orthopedic surgery: a case report.

Science.gov (United States)

Gazzaniga, David; Brenton, Ashley; Meshkin, Brian

2017-02-24

Precision medicine is a promising technology in patient care that combines genetic analysis with clinical data, such as health, behavioral, functional, environment, and lifestyle information. Here we present the case of a 54-year old woman who, following an accident, had uncontrolled chronic pain and was subsequently labeled a drug seeker. A 54-year-old white woman who was experiencing severe calf pain was referred for treatment. Her pain was insufficiently controlled immediately following knee arthroplasty with multiple opioid medications, as well as non-opioids. Precision medicine testing was ordered for her so that we could assess her pain sensitivity objectively to determine if the pill seeker designation was correct and to determine the best medications for her. Based on the Proove profiles, we determined that she had moderately low pain sensitivity, which means that clinically she may underreport pain and may have decreased medication needs. This result suggested that her continued reporting of unresolved pain was probably due to a condition unresolved by her right knee arthroplasty. In addition, she was found to be at low risk of opioid addiction, based on the Proove Opioid Risk Profile. Taken together, along with the high levels of pain she described, we determined that her pain was not properly controlled and that the designation of pill seeker was incorrect. The next step was to determine which medications and which doses would result in the most favorable outcomes for our patient. To determine this, we used the results of the Proove Opioid Response, Proove Drug Metabolism, and Proove Non-Opioid Profiles to guide her treatment. We reduced her pain medications to a single opioid, Vicodin (acetaminophen and hydrocodone), which also eliminated the adverse side effects she experienced. Precision medicine offers an important health care decision tool which can reduce emotional and physical costs to patients and may reduce the economic health care burden of

Do we have to Include HCI Issues in Clinical Trials of Medical Devices?

DEFF Research Database (Denmark)

Nielsen, Lene; Christensen, Lars Rune; Sabers, Anne

2017-01-01

Digital devices play an important role in medical treatment and will in the future play a larger role in connection to cures of health-related issues. Traditionally medicine has been tested by clinical double blind, randomized trials to document the efficacy and safety profile. When it comes to t...

Legal issues relating to the feed-in of biogas under the Gas Network Access Ordinance; Rechtsfragen der Biogaseinspeisung nach der GasNZV

Energy Technology Data Exchange (ETDEWEB)

Stappert, Holger; Johannsen, Sven Leif Erik [Luther Rechtsanwaltsgesellschaft mbH, Duesseldorf (Germany)

2012-07-01

In the authors' view, the legislature has set itself ambitious goals in regulating the feed-in of biogas into the natural gas grid. Aside from the economic considerations that are leading investors to prefer other investment opportunities there are also a number of unresolved technical issues relating to the feed-in of biogas. Furthermore, network operators find themselves confronted with considerable legal uncertainty as they process grid connection applications, i.e. in the time interval from application submission until contract conclusion. In spite of being allowed only 3 months for processing connection applications, grid operators are required to bind themselves to a high degree in approving an application. This is a particular cause of difficulty given the as yet unresolved technical problems and is accordingly subject to controversy. In those difficult cases where it not possible to guarantee year-round feed-in of biogas into the grid because of unavailability of deodorant plants that would be needed for the ability to backfeed biogas into upstream grids, resolution would often nevertheless be possible if it was clearly indicated that use of a ''bypass solution'' as a means of ensuring overall cost-effectiveness would be accepted as a capacity-enhancing measure for purposes of cost allocation. This would provide grid operators a way of reliably circumventing the technical difficulties associated with deodorisation, enabling them to connect biogas production plants to the grid without having to deal with these technical issues which still await their final resolution. Under the law currently in force there is no legal impediment, subject to the specifics of the individual case, to accepting a bypass solution as a capacity enhancing measure. It would help grid operators in obtaining legal certainty, and ultimately promote investment in biogas projects, if the legislature were to clarify these issues in the Gas Network Access Ordinance.

Mean propagation kernels for transport in correlated stochastic media at unresolved scales, illustration with a problem in atmospheric radiation

International Nuclear Information System (INIS)

Davis, A. B.

2007-01-01

A simple and effective framework is presented for modeling transport processes unfolding at computationally and/or observationally unresolved scales in scattering, absorbing and emitting media. The new approach acts directly on the spatial (i.e., propagation) part of the kernel in the integral formulation of the generic linear transport equation framed for stochastic media with a wide variety of spatial correlations, going far beyond the Markov-Poisson class used in the classic Pomraning-Levermore model. This statistical look at the extinction of un-collided particle beams takes us away from the standard exponential law of transmission. New transmission laws arise that are generally not exponential, often not even for asymptotically large jumps. This means that, from this perspective on random spatial variability, there is no 'effective medium' per se nor homogenization technique that can be used to describe the effects of unresolved fluctuations of the collision coefficient. However, one can still rewrite the transport equation, at least in its integral form, in a manner that looks like its counterpart for uniform media, but with a modified propagation kernel. Implementation in a Monte Carlo scheme is trivially simple and numerical results are presented that illustrate the bulk effect of the new parameterization for plane-parallel geometry. We survey time-domain diagnostics of solar radiative transfer in the Earth's cloudy atmosphere obtained recently from high-resolution ground-based spectroscopy, and it is shown that they are explained comprehensively by the new model. Finally, we discuss possible applications of this modeling framework in nuclear engineering. (authors)

Temporal behavior of unresolved transition array emission in water window soft x-ray spectral region from multiply charged ions

Energy Technology Data Exchange (ETDEWEB)

Dinh, Thanh-Hung, E-mail: dinh@cc.utsunomiya-u.ac.jp; Suzuki, Yuhei; Arai, Goki; Higashiguchi, Takeshi, E-mail: higashi@cc.utsunomiya-u.ac.jp [Department of Electrical and Electronic Engineering, Faculty of Engineering and Center for Optical Research and Education (CORE), Utsunomiya University, Yoto 7-1-2, Utsunomiya, Tochigi 321-8585 (Japan); Li, Bowen [School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000 (China); Dunne, Padraig; O' Sullivan, Gerry [School of Physics, University College Dublin, Belfield, Dublin 4 (Ireland); Fujioka, Shinsuke [Institute of Laser Engineering, Osaka University, 2-6 Yamada-oka, Suita, Osaka 565-0871 (Japan); Hasegawa, Noboru; Kawachi, Tetsuya; Nishikino, Masaharu [Quantum Beam Science Center, Japan Atomic Energy Agency, 8-1-7 Umemidai, Kizugawa, Kyoto 619-0215 (Japan)

2015-09-21

We have characterized the spectral structure and the temporal history of the laser-produced high-Z multi-charged ion plasmas for the efficient water window soft x-ray sources. Strong unresolved transition array emission was observed due to 4d–4f and 4f–5g transitions from Au, Pb, and Bi plasmas in the 280–700 eV photon energy region. The temporal behavior of the emission was essentially similar of that of the laser pulse with a slight delay between different transitions. These results provide feedback for accurate modeling of the atomic processes with the radiative hydrodynamic simulations.

Expanding Horizons and Unresolved Conundrums: Language Testing and Assessment

Science.gov (United States)

Leung, Constant; Lewkowicz, Jo

2006-01-01

Since the last "TESOL Quarterly" commemorative issue 15 years ago, there have been too many important developments in language testing and assessment for all of them to be discussed in a single article. Therefore, this article focuses on issues that we believe are integrally linked to pedagogic and curriculum concerns of English language teaching.…

Widening Access to Scottish Higher Education: Unresolved Issues and Future Challenges

Science.gov (United States)

Riddell, Sheila

2016-01-01

Despite the Scottish Government's frequent affirmation of its commitment to social justice principles, there has of late been a recognition of the need for firmer action to tackle the social class gap in higher education participation, reflecting wider social inequalities in Scotland. In a recent policy statement, Angela Constance, Cabinet…

Fire Risk Scoping Study: Investigation of nuclear power plant fire risk, including previously unaddressed issues

International Nuclear Information System (INIS)

Lambright, J.A.; Nowlen, S.P.; Nicolette, V.F.; Bohn, M.P.

1989-01-01

An investigation of nuclear power plant fire risk issues raised as a result of the USNRC sponsored Fire Protection Research Program at Sandia National Laboratories has been performed. The specific objectives of this study were (1) to review and requantify fire risk scenarios from four fire probabilistic risk assessments (PRAs) in light of updated data bases made available as a result of USNRC sponsored Fire Protection Research Program and updated computer fire modeling capabilities, (2) to identify potentially significant fire risk issues that have not been previously addressed in a fire risk context and to quantify the potential impact of those identified fire risk issues where possible, and (3) to review current fire regulations and plant implementation practices for relevance to the identified unaddressed fire risk issues. In performance of the fire risk scenario requantifications several important insights were gained. It was found that utilization of a more extensive operational experience base resulted in both fire occurrence frequencies and fire duration times (i.e., time required for fire suppression) increasing significantly over those assumed in the original works. Additionally, some thermal damage threshold limits assumed in the original works were identified as being nonconservative based on more recent experimental data. Finally, application of the COMPBRN III fire growth model resulted in calculation of considerably longer fire damage times than those calculated in the original works using COMPBRN I. 14 refs., 2 figs., 16 tabs

Resolution of the reactor vessel materials toughness safety issue; Task Action Plan A-11; Appendices C-K

International Nuclear Information System (INIS)

Johnson, R.E.

1981-09-01

The central problem in the Unresolved Safety Issue A-11, 'Reactor Vessel Materials Toughness,' was to provide guidance in performing analyses for reactor pressure vessels (RPVs) which fail to meet the toughness requirements during service life as a result of neutron radiation embrittlement. A technical team of recognized experts was organized to assist the NRC staff in addressing the problem. Using the foundation of the tearing modulus concept, which has been developed under earlier NRC sponsorship, relationships were obtained which provided approximate solutions to the RPV fracture problem with assumed beltline region flaws. Volume I of this report is a brief presentation of the problem and the results; Volume II provides the detailed technical foundations

Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions

Science.gov (United States)

Clemente, Maria Grazia; Mandato, Claudia; Poeta, Marco; Vajro, Pietro

2016-01-01

Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A “multiple-hit” pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stress due to genetic/epigenetic background, unfavorable lifestyles, gut microbiota and gut-liver axis dysfunction, and perturbations of trace element homeostasis have been shown to be critical for disease progression and the development of more severe inflammatory and fibrotic stages [non-alcoholic steatohepatitis (NASH)]. Simple clinical and laboratory parameters, such as age, history, anthropometrical data (BMI and waist circumference percentiles), blood pressure, surrogate clinical markers of IR (acanthosis nigricans), abdominal ultrasounds, and serum transaminases, lipids and glucose/insulin profiles, allow a clinician to identify children with obesity and obesity-related conditions, including NAFLD and cardiovascular and metabolic risks. A liver biopsy (the “imperfect” gold standard) is required for a definitive NAFLD/NASH diagnosis, particularly to exclude other treatable conditions or when advanced liver disease is expected on clinical and laboratory grounds and preferably prior to any controlled trial of pharmacological/surgical treatments. However, a biopsy clearly cannot represent a screening procedure. Advancements in diagnostic serum and imaging tools, especially for the non-invasive differentiation between NAFLD and NASH, have shown promising results, e.g., magnetic resonance elastography. Weight loss and physical activity should be the first option of intervention. Effective pharmacological treatments are still under development; however, drugs targeting IR, oxidative stress, proinflammatory pathways, dyslipidemia, gut microbiota and gut liver axis dysfunction are an option for patients who are unable to comply with the recommended

Identification of unresolved complex mixtures (UCMs) of hydrocarbons in commercial fish oil supplements.

Science.gov (United States)

Reid, Anna-Jean M; Budge, Suzanne M

2015-01-01

Heightened awareness of the health benefits of fish oil consumption has led to a great increase in the number of fish oil supplements available to the consumer. Therefore manufacturers are continually looking for ways to distinguish their products from those of competitors. Minimally refined or virgin fish oils provide a unique feature; however, petroleum hydrocarbon contamination from oil spills is a reality in the world's oceans. The question arises whether oil produced from fish species caught in these polluted areas is free of petroleum hydrocarbons, with particular interest in unresolved complex mixtures (UCMs). This study investigates the presence of UCMs in commercially available fish oil supplements advertised as being virgin, as well as refined. Weathered petroleum hydrocarbons in the form of a UCM were found at 523 µg g(-1) in a virgin Alaskan salmon oil supplement. Supplements that were refined were free of this contamination. Fish used in the production of fish oil supplements appear to have accumulated petrogenic hydrocarbons in their tissues which were not removed by minimal oil refining. Further study is required to determine if there are any health implications associated with long-term consumption of these contaminated supplements. © 2014 Society of Chemical Industry.

An analytic approach to probability tables for the unresolved resonance region

Directory of Open Access Journals (Sweden)

Brown David

2017-01-01

Full Text Available The Unresolved Resonance Region (URR connects the fast neutron region with the Resolved Resonance Region (RRR. The URR is problematic since resonances are not resolvable experimentally yet the fluctuations in the neutron cross sections play a discernible and technologically important role: the URR in a typical nucleus is in the 100 keV – 2 MeV window where the typical fission spectrum peaks. The URR also represents the transition between R-matrix theory used to described isolated resonances and Hauser-Feshbach theory which accurately describes the average cross sections. In practice, only average or systematic features of the resonances in the URR are known and are tabulated in evaluations in a nuclear data library such as ENDF/B-VII.1. Codes such as AMPX and NJOY can compute the probability distribution of the cross section in the URR under some assumptions using Monte Carlo realizations of sets of resonances. These probability distributions are stored in the so-called PURR tables. In our work, we begin to develop a scheme for computing the covariance of the cross section probability distribution analytically. Our approach offers the possibility of defining the limits of applicability of Hauser-Feshbach theory and suggests a way to calculate PURR tables directly from systematics for nuclei whose RRR is unknown, provided one makes appropriate assumptions about the shape of the cross section probability distribution.

Means-end chains and laddering: An inventory of problems and an agenda for research

DEFF Research Database (Denmark)

Grunert, Klaus G.; Beckmann, Suzanne C.; Sørensen, Elin

2001-01-01

and unconscious (or, at least, semiconscious) factors. It is intuitively appealing to the practitioner but has, likewise, attracted academic research. Increased acceptance and use of a new approach inevitably leads to the detection of unresolved issues and problems. Many of these unresolved issues are related...... to the collection and analysis of laddering data. However, many of these also point at problems of a more theoretical nature. In this chapter presented are some of the issues regarded as unresolved and suggested research that could help in solving these problems. The mayor part of this chapter deals...... with methodological problems of the interview technique called laddering, og coding laddering data, and of analysing the coded data. However, also shown, methodological and theoretical issues are partly interlinked: resolutions of methodological problems may require theoretical progress or at least a clarification...

When Others' Performance Just Isn't Good Enough: Educational Leaders' Framing of Concerns in Private and Public

Science.gov (United States)

Sinnema, Claire E. L.; Le Fevre, Deidre; Robinson, Viviane M. J.; Pope, Denyse

2013-01-01

Effective instructional leadership demands that leaders address the inevitable problems and concerns that exist in any educational organization. Unfortunately, much evidence suggests that many important concerns, including teacher performance issues, continue to be unaddressed and unresolved. This article portrays the nature of concerns facing 77…

Deaf murderers: clinical and forensic issues.

Science.gov (United States)

Vernon, M; Steinberg, A G; Montoya, L A

1999-01-01

Data are reported on 28 deaf individuals who were convicted, pled guilty, or have been charged and awaiting trial for murder. The unique forensic issues raised by these cases are discussed, and their clinical picture presented. A significant percentage of these deaf murderers and defendants had such severely limited communication skills in both English and American Sign Language that they lacked the linguistic ability to understand the charges against them and/or to participate in their own defense. As such, they were incompetent to stand trial, due not to mental illness or mental retardation, but to linguistic deficits. This form of incompetence poses a dilemma to the courts that remains unresolved. This same linguistic disability makes it impossible for some deaf suspects to be administered Miranda Warnings in a way comprehensible to them. This paper identifies the reasons for the communication problems many deaf persons face in court and offers remedial steps to help assure fair trials and police interrogations for deaf defendants. The roles and responsibilities of psychiatric and psychological experts in these cases are discussed. Data are provided on the etiology of the 28 individuals' hearing losses, psychiatric/psychological histories, IQs, communication characteristics, educational levels, and victim characteristics. Copyright 1999 John Wiley & Sons, Ltd.

SKB annual report 1993. Including summaries of technical reports issued during 1993

International Nuclear Information System (INIS)

1994-05-01

This is the annual report on the activities of the Swedish Nuclear and Waste Management Co., SKB. It contains in part I an overview of SKB activities in different fields. Part II gives a description of the research and development work on nuclear waste disposal performed during 1993. Lectures and publications during 1993 as well as reports issued in the SKB technical series are listed in part III. Part IV contains the summaries of all technical reports issued during 1993. SKB is the owner of CLAB, the Central Facility for Interim Storage of Spent Nuclear Fuel, located at Oskarshamn. CLAB was taken into operation in July 1985 and to the end of 1993 in total 1 885 tonnes of spent fuel (measured as uranium) have been received. Transportation from the nuclear sites to CLAB is made by a special ship, M/S Sigyn. At Forsmark the final repository for Radioactive Waste - SFR - was taken into operation in April 1988. The repository is situated in crystalline rock under the Baltic Sea. At the end of 1993 a total of 13 000 m 3 of waste have been deposited in SFR. SKB is in charge of a comprehensive research and development programme on geological disposal of nuclear waste. Some of the main areas for SKB research are: Groundwater movements; Bedrock stability; Groundwater chemistry and nuclide migration; Methods and instruments for in situ characterization of crystalline bedrock; Characterization and leaching of spent nuclear fuel; Properties of bentonite for buffer, backfilling and sealing; Radionuclide transport in biosphere and dose evaluations; Development of performance and safety assessment methodology and assessment models; Construction of an underground research laboratory

Wellhead and tree standards updated

International Nuclear Information System (INIS)

Dach, A.J. Jr.; Haeberle, T.

1996-01-01

Revisions in the API 6A, 17th Edition, have resolved a number of long-term problems and expanded its scope and coverage of wellhead and christmas tree equipment. The 17th Edition, Feb. 1, 1996, represents the state-of-the-art in international requirements for wellhead and christmas tree equipment. The design, materials, and quality control aspects of API 6A have all been improved with an emphasis on making the document more acceptable around the world. However, there are unresolved issues that raise many questions about the future direction of efforts aimed at international standardization of wellhead and christmas tree equipment. Unfortunately, these unresolved issues confuse both manufacturers and companies purchasing this equipment. This ultimately increases wellhead and christmas tree costs, so it is to everyone's advantage to resolve these issues. This article describes the significant revisions that are included in API 6A, 17th Edition. Also discussed are the regulatory, standardization, and customer acceptance issues that cloud the future of API 6A, 17th Edition

Issues in energy finance

Science.gov (United States)

Khokher, Zeigham Islam

As opposed to the well developed and understood equity markets, the energy markets are still in their infancy. The explosion of contracts, of both the primary and derivative types, are testament both to the existing size and the untapped growth potential of this exciting industry. However, because of its relative youth many basic issues in the energy markets remain unresolved. This thesis introduces some interesting questions and provides insights into these issues. Thematically, the chapters of this thesis are linked by an emphasis on valuation and risk management decisions. A contribution of this thesis is to show that subtle differences between the endogenous price process in our general equilibrium setting and the exogenous processes considered in earlier papers can generate significant differences in both financial and real option values. In addition to these valuation concerns there has been much debate about the corporate risk management function. Finance theory suggests that a value maximizing corporation should either be indifferent to hedging or, in the presence of certain imperfections, it should completely hedge all exposures. Both these extremes contradict empirical evidence. We show that existing corporate hedging behaviour is best explained in light of both physical market imperfections and directional predictions on future prices. While these speculative motives may arise from corporate hubris or genuine informational advantages, we argue that it would be difficult to implement private information in the absence of noise traders. Related to the risk management decision is the existence of futures risk premia. These premia have been thought to be cause by covariance with priced factors or due to the hedging demands of consumers and producers. This thesis argues that inventories serve as a signal of available quantity, which coupled with consumers fears regarding stockouts can induce a positive relationship between premia and inventories. In

The unresolved issue of oxygen therapy in lung fibrosis: Some clues from a Spanish cohort

Directory of Open Access Journals (Sweden)

Irene Martin-Robles

2014-01-01

Full Text Available Indication of oxygen therapy in fibrotic interstitial lung diseases is not standardized and its specific requirements are not well defined. The objective of this study was to evaluate ambulatory oxygen therapy features in lung fibrotic patients. Clinical and exploratory　data, including 6-minute walking test and pulmonary hypertension, from one hundred and seven patients with fibrotic interstitial lung disease that received ambulatory oxygen treatment were studied. In up to 40% of cases the prescription of oxygen therapy was made after performing a 6-minute walking test. Patients who required ambulatory oxygen only during exercise presented a mild to moderate reduction of the predicted % FVC (62.1 ± 19 and DLCO (49 ± 14.4 while patients who had respiratory failure at rest (mean PaO2 51.9 ± 6.7 presented a moderate reduction of %FVC (56.8 ± 15.6 but a severe decrease of %DLCO (31.67 ± 12. Pulmonary hypertension (PH was evaluated in 47.7% of patients and occurred in 60.8% of them. In conclusion, there is no pulmonary functional predictor of oxyhaemoglobin desaturation during exercise. PH is frequently associated with interstitial lung diseases, mainly when respiratory failure at rest appears. The heterogeneity of the patients and limitation of retrospective studies could be the cause of the tributes for potential benefits of oxygen treatment in interstitial lung diseases.

Liquid lithium loop system to solve challenging technology issues for fusion power plant

Science.gov (United States)

Ono, M.; Majeski, R.; Jaworski, M. A.; Hirooka, Y.; Kaita, R.; Gray, T. K.; Maingi, R.; Skinner, C. H.; Christenson, M.; Ruzic, D. N.

2017-11-01

Steady-state fusion power plant designs present major divertor technology challenges, including high divertor heat flux both in steady-state and during transients. In addition to these concerns, there are the unresolved technology issues of long term dust accumulation and associated tritium inventory and safety issues. It has been suggested that radiation-based liquid lithium (LL) divertor concepts with a modest lithium-loop could provide a possible solution for these outstanding fusion reactor technology issues, while potentially improving reactor plasma performance. The application of lithium (Li) in NSTX resulted in improved H-mode confinement, H-mode power threshold reduction, and reduction in the divertor peak heat flux while maintaining essentially Li-free core plasma operation even during H-modes. These promising results in NSTX and related modeling calculations motivated the radiative liquid lithium divertor concept and its variant, the active liquid lithium divertor concept, taking advantage of the enhanced or non-coronal Li radiation in relatively poorly confined divertor plasmas. To maintain the LL purity in a 1 GW-electric class fusion power plant, a closed LL loop system with a modest circulating capacity of ~1 l s-1 is envisioned. We examined two key technology issues: (1) dust or solid particle removal and (2) real time recovery of tritium from LL while keeping the tritium inventory level to an acceptable level. By running the LL-loop continuously, it can carry the dust particles and impurities generated in the vacuum vessel to the outside where the dust/impurities can be removed by relatively simple dust filter, cold trap and/or centrifugal separation systems. With ~1 l s-1 LL flow, even a small 0.1% dust content by weight (or 0.5 g s-1) suggests that the LL-loop could carry away nearly 16 tons of dust per year. In a 1 GW-electric (or ~3 GW fusion power) fusion power plant, about 0.5 g s-1 of tritium is needed to maintain the fusion fuel cycle

Unresolved transition array based water window soft x-ray source by laser-produced high-Z plasma

International Nuclear Information System (INIS)

Higashiguchi, Takeshi; Dunne, Padraig; O'Sullivan, Gerry

2013-01-01

We demonstrate a table-top broadband emission water window source based on laser-produced high-Z plasmas. resonance emission from multiply charged ions merges to produce intense unresolved transition arrays (UTAs) in the 2 to 4 nm region, extending below the carbon K edge (4.37 nm). Arrays resulting from n=4-n=4 transitions are overlaid with n=4-n=5 emission and shift to shorter wavelength with increasing atomic number. An outline of a microscope design for single-shot live cell imaging is proposed based on a bismuth plasma UTA source, coupled to multilayer mirror optics. At power densities available from 'table-top' solid-state lasers, comparison of emission from a number of targets has shown that 3d-4f UTA in zirconium plasmas have highest overall brightness and in an imaging system based on reflective multilayer mirrors, may, depending on bandwidth, have superior performance than either line or broader-band sources. (author)

Space Station Engineering Design Issues

Science.gov (United States)

Mcruer, Duane T.; Boehm, Barry W.; Debra, Daniel B.; Green, C. Cordell; Henry, Richard C.; Maycock, Paul D.; Mcelroy, John H.; Pierce, Chester M.; Stafford, Thomas P.; Young, Laurence R.

1989-01-01

Space Station Freedom topics addressed include: general design issues; issues related to utilization and operations; issues related to systems requirements and design; and management issues relevant to design.

Resolution of thermal-hydraulic safety and licensing issues for the system 80+trademark design

International Nuclear Information System (INIS)

Carpentino, S.E.; Ritterbusch, S.E.; Schneider, R.E.

1995-01-01

The System 80+ trademark Standard Design is an evolutionary Advanced Light Water Reactor (ALWR) with a generating capacity of 3931 MWt (1350 MWe). The Final Design Approval (FDA) for this design was issued by the Nuclear Regulatory Commission (NRC) in July 1994. The design certification by the NRC is anticipated by the end of 1995 or early 1996. NRC review of the System 80+ design has involved several new safety issues never before addressed in a regulatory atmosphere. In addition, conformance with the Electric Power Research Institute (EPRI) ALWR Utility Requirements Document (URD) required that the System 80+ plant address nuclear industry concerns with regard to design, construction, operation and maintenance of nuclear power plants. A large number of these issues/concerns deals with previously unresolved generic thermal-hydraulic safety issues and severe accident prevention and mitigation. This paper discusses the thermal-hydraulic analyses and evaluations performed for the System 80+ design to resolve safety and licensing issues relevant to both the Nuclear Stream Supply System (NSSS) and containment designs. For the NSSS design, the Safety Depressurization System mitigation capability and resolution of the boron dilution concern are described. Examples of containment design issues dealing with containment shell strength, robustness of the reactor cavity walls and hydrogen mixing under severe accident conditions are also provided. Finally, the overall approach used in the application of NRC's new (NUREG-1465) radiological source term for System 80+ evaluation is described. The robustness of the System 80+ containment design to withstand severe accident consequences was demonstrated through detailed thermal-hydraulic analyses and evaluations. This advanced design to shown to meet NRC severe accident policy goals and ALWR URD requirements without any special design features and unnecessary costs

Global Issues

Energy Technology Data Exchange (ETDEWEB)

Seitz, J.L.

2001-10-15

Global Issues is an introduction to the nature and background of some of the central issues - economic, social, political, environmental - of modern times. This new edition of this text has been fully updated throughout and features expanded sections on issues such as global warming, biotechnology, and energy. Fully updated throughout and features expanded sections on issues such as global warming, biotechnology, and energy. An introduction to the nature and background of some of the central issues - economic, social, political, environmental - of modern times. Covers a range of perspectives on a variety of societies, developed and developing. Extensively illustrated with diagrams and photographs, contains guides to further reading, media, and internet resources, and includes suggestions for discussion and studying the material. (author)

Could a Change in Diet Revitalize Children Who Suffer from Unresolved Fatigue?

Directory of Open Access Journals (Sweden)

Tessa Gerjanne Steenbruggen

2015-03-01

Full Text Available Many children deal with fatigue for which no proper treatment can be given. A possible explanation for their fatigue is a micro deficiency of minerals and vitamins. In this non-randomized controlled trial, we clinically evaluated symptoms of fatigue in children for whom a nutrient-rich diet was advised. A group of 98 children (2–18 years old with unexplained symptoms of fatigue was examined. The dietary modifications consisted of green vegetables, beef, whole milk and full-fat butter. Children in the intervention group were asked to follow the diet for three months, whereas the control-group followed their normal diet. The primary outcome was symptoms of fatigue, as determined by a PedsQL Multidimensional Fatigue Scale, and secondary outcomes were compliance with the diet and BMI. Children, who followed the diet showed a significant decrease in the need to sleep (CI 0.83; 14.86, p = 0.03. They slept better through the night and took fewer naps. When analyzing components of the advised diet separately, a significant larger decrease in cognitive fatigue symptoms was seen for eating green vegetables according to the diet guidelines (CI 2.27; 30.63, p = 0.024. Furthermore, a lower need to sleep was seen when whole milk was consumed almost daily (CI 0.02; 14.62, p = 0.049. Our study showed that nutritional advice is an elegant, and effective method for decreasing some symptoms of medically unresolved fatigue in children.

Review on the NEI Methodology of Debris Transport Analysis in Sump Blockage Issue for APR1400

International Nuclear Information System (INIS)

Kim, Jong Uk; Lee, Jeong Ik; Hong, Soon Joon; Lee, Byung Chul; Bang, Young Seok

2007-01-01

Since USNRC (United State Nuclear Regulatory Committee) initially addressed post-accident sump performance under Unresolved Safety Issue USI A-43, sump blockage issue has gone through GSI-191, Regulation Guide 1.82, Rev. 3 (RG. 1.82 Rev.3), and generic Letter 2004-02 for PWRs (Pressurized Water Reactors). As a response of these USNRC's activities, NEI 04-07 was issued in order to evaluate the post-accident performance of a plant's recirculation sump. The baseline methodology of NEI 04-07 is composed of break selection, debris generation, latent debris, debris transport, and head loss. In analytical refinement of NEI 04-07, computational fluid dynamic (CFD) is suggested for the evaluation of debris transport in emergency core cooling (ECC) recirculation mode as guided by RG. 1.82 Rev.3. In Korea nuclear industry also keeps step with international activities of this safety issue, with Kori 1 plant as a pioneering edge. Korean nuclear industry has been also pursuing development of an advanced PWR of APR1400, which incorporates several improved safety features. One of the key features, considering sump blockage issue, is the adoption of IRWST (In-containment Refueling Water Storage Tank). This device, as the acronym implies, changes the emergency core cooling water injection pattern. This fact makes us to review the applicability of NEI 04-07's methodology. In this paper we discuss the applicability of NEI 04- 07's methodology, and more over, new methodology is proposed. And finally the preliminary debris transport is analyzed

Shutdown decay heat removal analysis: Plant case studies and special issues: Summary report

International Nuclear Information System (INIS)

Ericson, D.M. Jr.; Cramond, W.R.; Sanders, G.A.; Hatch, S.W.

1989-04-01

Shutdown Decay Heat Removal Requirements has been designated as Unresolved Safety Issue (USI) A-45. The overall objectives of the USI A-45 program were to evaluate the safety adequacy of decay heat removal (DHR) systems in existing light water reactor nuclear power plants and to assess the value and impact (benefit-cost) of alternative measures for improving the overall reliability of the DHR function. To provide the technical data required to meet these objectives a program was developed that examined the state of DHR system reliability in a sample of existing plants. This program identified potential vulnerabilities and identified and established the feasibility of potential measures to improve the reliability of the DHR function. A value/impact (V/I) analysis of the more promising of such measures was conducted and documented. This report summarizes those studies. In addition, because of the evolving nature of V/I analyses in support of regulation, a number of supporting studies related to appropriate procedures and measures for the V/I analyses were also conducted. These studies are also summarized herein. This report only summarizes findings of technical studies performed by Sandia National Laboratories as part of the program to resolve this issue. 46 refs., 7 figs., 124 tabs

The Dutch Lifelong Learning scene : Continuing unresolved issues and two alternative perspectives

NARCIS (Netherlands)

van Dellen, Teije

2015-01-01

Lifelong learning (LLL) in the Netherlands is under debate in this article. The article shows the state of the art of the Dutch lifelong learning education, and training and development field. In particular the unfulfilled expectations of the field are shown in a polemic manner by discussing the

Dorsal-ventral patterning in amphioxus: current understanding, unresolved issues, and future directions

Czech Academy of Sciences Publication Activity Database

Kozmiková, Iryna; Yu, J.K.

2017-01-01

Roč. 61, č. 10-12 (2017), s. 601-610 ISSN 0214-6282 R&D Projects: GA ČR GC15-21285J Institutional support: RVO:68378050 Keywords : dorsal-ventral patterning * organizer * signaling pathway * chordate * evolution Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology Impact factor: 1.981, year: 2016

Special Education History, Current Status and Future: India

Science.gov (United States)

Antony, Pavan John

2013-01-01

Education of all children in public schools, including those with disabilities, continues to be an unresolved issue in many countries around the globe. While education of all children is mandated by law and considered a basic human right in many countries, the current status of implementation varies. India, for example, is an ancient country that…

Resolution of thermal-hydraulic safety and licensing issues for the system 80+{sup {trademark}} design

Energy Technology Data Exchange (ETDEWEB)

Carpentino, S.E.; Ritterbusch, S.E.; Schneider, R.E. [ABB-Combustion Engineering, Windsor, CT (United States)] [and others

1995-09-01

The System 80+{sup {trademark}} Standard Design is an evolutionary Advanced Light Water Reactor (ALWR) with a generating capacity of 3931 MWt (1350 MWe). The Final Design Approval (FDA) for this design was issued by the Nuclear Regulatory Commission (NRC) in July 1994. The design certification by the NRC is anticipated by the end of 1995 or early 1996. NRC review of the System 80+ design has involved several new safety issues never before addressed in a regulatory atmosphere. In addition, conformance with the Electric Power Research Institute (EPRI) ALWR Utility Requirements Document (URD) required that the System 80+ plant address nuclear industry concerns with regard to design, construction, operation and maintenance of nuclear power plants. A large number of these issues/concerns deals with previously unresolved generic thermal-hydraulic safety issues and severe accident prevention and mitigation. This paper discusses the thermal-hydraulic analyses and evaluations performed for the System 80+ design to resolve safety and licensing issues relevant to both the Nuclear Stream Supply System (NSSS) and containment designs. For the NSSS design, the Safety Depressurization System mitigation capability and resolution of the boron dilution concern are described. Examples of containment design issues dealing with containment shell strength, robustness of the reactor cavity walls and hydrogen mixing under severe accident conditions are also provided. Finally, the overall approach used in the application of NRC`s new (NUREG-1465) radiological source term for System 80+ evaluation is described. The robustness of the System 80+ containment design to withstand severe accident consequences was demonstrated through detailed thermal-hydraulic analyses and evaluations. This advanced design to shown to meet NRC severe accident policy goals and ALWR URD requirements without any special design features and unnecessary costs.

Safeguarding patient privacy in electronic healthcare in the USA: the legal view.

Science.gov (United States)

Walsh, Diana; Passerini, Katia; Varshney, Upkar; Fjermestad, Jerry

2008-01-01

The conflict between the sweeping power of technology to access and assemble personal information and the ongoing concern about our privacy and security is ever increasing. While we gradually need higher electronic access to medical information, issues relating to patient privacy and reducing vulnerability to security breaches surmount. In this paper, we take a legal perspective and examine the existing patchwork of laws and obligations governing health information in the USA. The study finds that as Electronic Medical Records (EMRs) increase in scope and dissemination, privacy protections gradually decrease due to the shortcomings in the legal system. The contributions of this paper are (1) an overview of the legal EMR issues in the USA, and (2) the identification of the unresolved legal issues and how these will escalate when health information is transmitted over wireless networks. More specifically, the paper discusses federal and state government regulations such as the Electronic Communications Privacy Act, the Health Insurance Portability and Accountability Act (HIPAA) and judicial intervention. Based on the legal overview, the unresolved challenges are identified and suggestions for future research are included.

Physician-Assisted Suicide and Euthanasia in the Intensive Care Unit: A Dialogue on Core Ethical Issues

Science.gov (United States)

Goligher, Ewan C.; Ely, E. Wesley; Sulmasy, Daniel P.; Bakker, Jan; Raphael, John; Volandes, Angelo E.; Patel, Bhavesh M.; Payne, Kate; Hosie, Annmarie; Churchill, Larry; White, Douglas B.; Downar, James

2016-01-01

Objective Many patients are admitted to the intensive care unit at or near the end of their lives. Consequently, the increasingly common debate regarding physician-assisted suicide and euthanasia (PAS/E) holds implications for the practice of critical care medicine. The objective of this manuscript is to explore core ethical issues related to PAS/E from the perspective of healthcare professionals and ethicists on both sides of the debate. Synthesis We identified four issues highlighting the key areas of ethical tension central to evaluating PAS/E in medical practice: (1) the benefit or harm of death itself, (2) the relationship between PAS/E and withholding or withdrawing life support, (3) the morality of a physician deliberately causing death, and (4) the management of conscientious objection related to PAS/E in the critical care setting. We present areas of common ground as well as important unresolved differences. Conclusions We reached differing positions on the first three core ethical questions and achieved significant agreement on how critical care clinicians should manage conscientious objections related to PAS/E. The alternative positions presented in this paper may serve to promote open and informed dialogue within the critical care community. PMID:28098622

Unresolved legal questions in cross-border health care in Europe: liability and data protection.

Science.gov (United States)

van der Molen, I N; Commers, M J

2013-11-01

Directive 2011/24/EU was designed to clarify the rights of EU citizens in evaluating, accessing and obtaining reimbursement for cross-border care. Based on three regional case studies, the authors attempted to assess the added value of the Directive in helping clarify issues in to two key areas that have been identified as barriers to cross-border care: liability and data protection. Qualitative case study employing secondary data sources including research of jurisprudence, that set up a Legal framework as a base to investigate liability and data protection in the context of cross-border projects. By means of three case studies that have tackled liability and data protection hurdles in cross-border care implementation, this article attempts to provide insight into legal certainty and uncertainty regarding cross-border care in Europe. The case studies reveal that the Directive has not resolved core uncertainties related to liability and data protection issues within cross-border health care. Some issues related to the practice of cross-border health care in Europe have been further clarified by the Directive and some direction has been given to possible solutions for issues connected to liability and data protection. Directive 2011/24/EU is clearly a transposition of existing regulations on data protection and ECJ case law, plus a set of additional, mostly, voluntary rules that might enhance regional border cooperation. Therefore, as shown in the case studies, a practical and case by case approach is still necessary in designing and providing cross-border care. © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Physician-Assisted Suicide and Euthanasia in the ICU: A Dialogue on Core Ethical Issues.

Science.gov (United States)

Goligher, Ewan C; Ely, E Wesley; Sulmasy, Daniel P; Bakker, Jan; Raphael, John; Volandes, Angelo E; Patel, Bhavesh M; Payne, Kate; Hosie, Annmarie; Churchill, Larry; White, Douglas B; Downar, James

2017-02-01

Many patients are admitted to the ICU at or near the end of their lives. Consequently, the increasingly common debate regarding physician-assisted suicide and euthanasia holds implications for the practice of critical care medicine. The objective of this article is to explore core ethical issues related to physician-assisted suicide and euthanasia from the perspective of healthcare professionals and ethicists on both sides of the debate. We identified four issues highlighting the key areas of ethical tension central to evaluating physician-assisted suicide and euthanasia in medical practice: 1) the benefit or harm of death itself, 2) the relationship between physician-assisted suicide and euthanasia and withholding or withdrawing life support, 3) the morality of a physician deliberately causing death, and 4) the management of conscientious objection related to physician-assisted suicide and euthanasia in the critical care setting. We present areas of common ground and important unresolved differences. We reached differing positions on the first three core ethical questions and achieved unanimity on how critical care clinicians should manage conscientious objections related to physician-assisted suicide and euthanasia. The alternative positions presented in this article may serve to promote open and informed dialogue within the critical care community.

PROPERTIES AND MODELING OF UNRESOLVED FINE STRUCTURE LOOPS OBSERVED IN THE SOLAR TRANSITION REGION BY IRIS

Energy Technology Data Exchange (ETDEWEB)

Brooks, David H. [College of Science, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States); Reep, Jeffrey W.; Warren, Harry P. [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States)

2016-08-01

Recent observations from the Interface Region Imaging Spectrograph ( IRIS ) have discovered a new class of numerous low-lying dynamic loop structures, and it has been argued that they are the long-postulated unresolved fine structures (UFSs) that dominate the emission of the solar transition region. In this letter, we combine IRIS measurements of the properties of a sample of 108 UFSs (intensities, lengths, widths, lifetimes) with one-dimensional non-equilibrium ionization simulations, using the HYDRAD hydrodynamic model to examine whether the UFSs are now truly spatially resolved in the sense of being individual structures rather than being composed of multiple magnetic threads. We find that a simulation of an impulsively heated single strand can reproduce most of the observed properties, suggesting that the UFSs may be resolved, and the distribution of UFS widths implies that they are structured on a spatial scale of 133 km on average. Spatial scales of a few hundred kilometers appear to be typical for a range of chromospheric and coronal structures, and we conjecture that this could be an important clue for understanding the coronal heating process.

Radiation Safety Issues in High Altitude Commercial Aircraft

Science.gov (United States)

Wilson, John W.; Cucinotta, Francis A.; Shinn, Judy L.

1995-01-01

The development of a global economy makes the outlook for high speed commercial intercontinental flight feasible, and the development of various configurations operating from 20 to 30 km have been proposed. In addition to the still unresolved issues relating to current commercial operations (12-16 km), the higher dose rates associated with the higher operating altitudes makes il imperative that the uncertainties in the atmospheric radiation environment and the associated health risks be re-examined. Atmospheric radiation associated with the galactic cosmic rays forms a background level which may, under some circumstances, exceed newly recommended allowable exposure limits proposed on the basis of recent evaluations of the A -bomb survivor data (due to increased risk coefficients). These larger risk coefficients, within the context of the methodology for estimating exposure limits, are resulting in exceedingly low estimated allowable exposure limits which may impact even present day flight operations and was the reason for the CEC workshop in Luxembourg (1990). At higher operating altitudes, solar particles events can produce exposures many orders of magnitude above background levels and pose significant health risks to the most sensitive individuals (such as during pregnancy). In this case the appropriate quality factors are undefined, and some evidence exists which indicates that the quality factor for stochastic effects is a substantial underestimate.

Issues in environmental survey design

International Nuclear Information System (INIS)

Iachan, R.

1989-01-01

Several environmental survey design issues are discussed and illustrated with surveys designed by Research Triangle Institute statisticians. Issues related to sampling and nonsampling errors are illustrated for indoor air quality surveys, radon surveys, pesticide surveys, and occupational and personal exposure surveys. Sample design issues include the use of auxiliary information (e.g. for stratification), and sampling in time. We also discuss the reduction and estimation of nonsampling errors, including nonresponse and measurement bias

Heart Failure: From Research to Clinical Practice.

Science.gov (United States)

Islam, Md Shahidul

2018-01-01

"Heart failure: from research to clinical practice", a collection of selected reviews, which comes out also as a book, covers essentially all important aspects of heart failure, including the pathogenesis, clinical features, biomarkers, imaging techniques, medical treatment and surgical treatments, use of pacemakers and implantable cardioverter defibrillators, and palliative care. The reviews include essential background information, state of the art, critical and in-depth analysis, and directions for future researches for elucidation of the unresolved issues. Everyone interested in heart failure is expected to find this compilation helpful for a deeper understanding of some of the complex issues.

The transportation issue management system: A tool for issue resolution

International Nuclear Information System (INIS)

Branch, K.M.; Boryczka, M.K.

1987-01-01

During the last decade, issue management programs have been developed and used by a number of large corporations in the United States. These systems have generally been designed to help senior program managers identify issues, develop strategic plans, and resolve issues. These systems involve scanning and abstracting literature to create a database that is then used for 1) issue identification, 2) issue analysis, 3) priority assessment, 4) development of corporate position/strategic options, and 5) action planning and implementation. Most of the existing systems rely on staff to identify trends in the computerized output, analyze the importance of the issue to the company, and assist in developing corporate responses. The Department of Energy has recently developed an issue management system for the Office of Civilian Radioactive Waste Management's (OCRWM) transportation program. This system is designed to help DOE identify institutional issues related to radioactive waste transportation, analyze the issues, and resolve them in a manner that is responsive to interested parties. The system will contain pertinent information from DOE technical reports, other federal documents, correspondence, professional journals, popular literature, newsclips, legislation and testimony. The program is designed around a number of institutional issues including: prenotification, physical protection procedures; highway, rail, and barge routing; inspections and enforcement of shipments; emergency response; liability, cask design and testing; overweight trucks; rail service; modal mix; infrastructure improvements; training standards, and operational procedures

Allergen-specific immunotherapy and risk of autoimmune disease

DEFF Research Database (Denmark)

Linneberg, Allan; Madsen, Flemming; Skaaby, Tea

2012-01-01

After 100 years of experience with allergen-specific immunotherapy (SIT), an issue that is still unresolved is whether SIT can act as a trigger of, or as a risk factor for, autoimmune disease. We searched the literature for evidence on this topic.......After 100 years of experience with allergen-specific immunotherapy (SIT), an issue that is still unresolved is whether SIT can act as a trigger of, or as a risk factor for, autoimmune disease. We searched the literature for evidence on this topic....

26 CFR 1.1273-2 - Determination of issue price and issue date.

Science.gov (United States)

2010-04-01

... (a), money includes functional currency and, in certain circumstances, nonfunctional currency. See § 1.988-2(b)(2) for circumstances when nonfunctional currency is treated as money rather than as... debt instruments in the issue is sold for money. (b) Publicly traded debt instruments issued for...

Future accelerators: physics issues

International Nuclear Information System (INIS)

Bjorken, J.D.

1977-11-01

High energy physics of the future using future accelerators is discussed. The proposed machines and instruments, physics issues and opportunities including brief sketches of outstanding recent results, and the way the proposed machines address these issues are considered. 42 references

Integration of generic issues

International Nuclear Information System (INIS)

Thatcher, D.

1989-01-01

The NRC has recognized the need to integrate generic issues (GIs). The GI process includes a number of phases, all of which should recognize the potential for overlap and conflict among related issues. In addition to the issues themselves, other related NRC and industry programs and activities need to be factored into the GI process. Integration has taken place, or is taking place, for a number of GIs. Each case of integration involves a specific set of circumstances and, as a result, the way in which integration proceeds can vary. This paper discusses the integration of issues in the generic issue process and provides a number of examples

Top-Ten IT Issues: 2009

Science.gov (United States)

Agee, Anne Scrivener; Yang, Catherine

2009-01-01

This article presents the top-ten IT-related issues in terms of strategic importance to the institution, as revealed by the tenth annual EDUCAUSE Current Issues Survey. These IT-related issues include: (1) Funding IT; (2) Administrative/ERP Information Systems; (3) Security; (4) Infrastructure/Cyberinfrastructure; (5) Teaching and Learning with…

Open Praxis vol. 8 issue 4

Directory of Open Access Journals (Sweden)

Inés Gil-Jaurena (ed., Various authors

2016-12-01

Full Text Available This last Open Praxis issue in 2016 is an open issue that includes four research papers, two innovative practice papers and two book reviews. It also includes the list of reviewers that have collaborated in volume 8.

Miscellaneous issues

International Nuclear Information System (INIS)

2002-01-01

The New Brunswick Market Design Committee has examined several issues regarding the restructuring of the province's electricity sector. This report presents issues that require guidance for implementation, with particular focus on options available for their resolutions. The issues include: (1) rate principles for stranded offer service (SOS) supply, (2) the ability of contestable customers to return to SOS after having left it, (3) whether loads embedded in distribution systems are eligible to participate in the bilateral contract market, (4) whether generators or suppliers can offer capacity and energy to SOS suppliers in competition with the SOS supplier, and (5) details for the balancing market, including pricing, bidding protocols, settlements and how intermittent power sources can participate in the market. A section on pricing for SOS explains pricing principles, the use of export profits, pricing for SOS capacity, and time of use pricing. The Committee has made recommendations for the electricity system in the province to have an energy imbalance service that can move towards a market in order to develop an efficient and effective service. This report also explains pricing in the balancing market, penalties, and settlements. 7 refs

Relationship between regulatory issues and probabilistic risk assessments

International Nuclear Information System (INIS)

Ilberg, D.; Papazoglou, I.

1985-01-01

The objective of this study was to obtain some perspective on the characteristics and the relative number of regulatory issues that are PRA related, i.e., can be effectively addressed by plant specific PRA studies. It was also aimed at developing approaches to resolution of regulatory issues as part of plant specific PRAs. Several ongoing NRC programs include a number of safety-related issues which are applicable to operating plants. A number of these issues include aspects that strongly interact with items addressed in PRA studies. The resolution of several generic issues using PRA studies has already started. A review of over 335 issues included in three NRC programs was conducted: Generic Issue Program (GI); Systematic Evaluation Program (SEP); and TMI Action Plan (TMI). The review identifid 240 items related to PRA, 120 of which were judged to have significant effect on core damage frequency. It is believed that these items can be effectively treated in a PRA study that includes internal and external events

Issues in waste combustion

Energy Technology Data Exchange (ETDEWEB)

Gustavsson, Lennart; Robertson, Kerstin; Tullin, Claes [Swedish National Testing and Research Inst., Boraas (Sweden); Sundquist, Lena; Wrangensten, Lars [AaF-Energikonsult AB, Stockholm (Sweden); Blom, Elisabet [AaF-Processdesign AB, Stockholm (Sweden)

2003-05-01

The main purpose of this review is to provide an overview of the state-of-the-art on research and development issues related to waste combustion with relevance for Swedish conditions. The review focuses on co-combustion in grate and fluidised bed furnaces. It is primarily literature searches in relevant databases of scientific publications with to material published after 1995. As a complement, findings published in different report series, have also been included. Since the area covered by this report is very wide, we do not claim to cover the issues included completely and it has not been possitile to evaluate the referred studies in depth. Basic knowledge about combustion issues is not included since such information can be found elsewhere in the literature. Rather, this review should be viewed as an overview of research and development in the waste-to-energy area and as such we hope that it will inspire scientists and others to further work in relevant areas.

A CROSS-MATCH OF 2MASS AND SDSS. II. PECULIAR L DWARFS, UNRESOLVED BINARIES, AND THE SPACE DENSITY OF T DWARF SECONDARIES

International Nuclear Information System (INIS)

Geissler, Kerstin; Metchev, Stanimir; Kirkpatrick, J. Davy; Berriman, G. Bruce; Looper, Dagny

2011-01-01

We present the completion of a program to cross-correlate the Sloan Digital Sky Survey Data Release 1 (SDSS DR1) and Two-Micron All-Sky Survey (2MASS) Point Source Catalog in search for extremely red L and T dwarfs. The program was initiated by Metchev and collaborators, who presented the findings on all newly identified T dwarfs in SDSS DR1 and estimated the space density of isolated T0-T8 dwarfs in the solar neighborhood. In the current work, we present most of the L dwarf discoveries. Our red-sensitive (z - J ≥ 2.75 mag) cross-match proves to be efficient in detecting peculiarly red L dwarfs, adding two new ones, including one of the reddest known L dwarfs. Our search also nets a new peculiarly blue L7 dwarf and, surprisingly, two M8 dwarfs. We further broaden our analysis to detect unresolved binary L or T dwarfs through spectral template fitting to all L and T dwarfs presented here and in the earlier work by Metchev and collaborators. We identify nine probable binaries, six of which are new and eight harbor likely T dwarf secondaries. We combine this result with current knowledge of the mass ratio distribution and frequency of substellar companions to estimate an overall space density of 0.005-0.05 pc -3 for individual T0-T8 dwarfs.

Hunger and Development [Issue Packet].

Science.gov (United States)

American Freedom from Hunger Foundation, Washington, DC.

A variety of informational materials is compiled in this issue packet concentrating on hunger and development. They have been assembled to understand the issues associated with the facts of world hunger and to try to invent new forms of action and thought necessary to find the possibilities hidden in the hunger issue. Items include: (1) a fact and…

Comparison of seismic margin assessment and probabilistic risk assessment in seismic IPE

International Nuclear Information System (INIS)

Reed, J.W.; Kassawara, R.P.

1993-01-01

A comparison of technical requirements and managerial issues between seismic margin assessment (SMA) and seismic probabilistic risk assessment (SPRA) in a seismic Individual Plant Examination (IPE) is presented and related to requirements for an Unresolved Safety Issue (USI) A-46 review which is required for older nuclear power plants. Advantages and disadvantages are discussed for each approach. Technical requirements reviewed for a seismic IPE include: scope of plants covered, seismic input, scope of review, selection of equipment, required experience and training of engineers, walkdown procedure, evaluation of components, relay review, containment review, quality assurance, products, documentation requirements, and closure procedure. Managerial issues discussed include regulatory acceptability, compatibility with seismic IPE, compliance with seismic IPE requirements, ease of use by utilities, and relative cost

Trends In U. S. Nuclear Plant Capacity Factor

Energy Technology Data Exchange (ETDEWEB)

Ross, D. F. [U. S. NRC Research, Washington (United States)

1986-04-15

Steam generator tube degradation in pressurized water reactors continues to be a matter of concern. The proposed resolution for this problem was discussed with the commission in September 1984. A letter was issued to PWR licensees in 1985, requesting that the industry describe their overall program for assuring steam generator tube integrity, in order to allow the staff to compare their actions with staff recommendations. The staff report, NUREG-0844, 'NRC Integrated Program for the Resolution of Unresolved Safety Issues A-3, A-4, and A-5 Regarding Steam Generator Tube Integrity,' was issued for public comment. The responses to these items are currently under review by the staff. Three reports on investigations of systems interaction search methods were issued by 1985. These studies complete technical work on the systems interactions issue. The proposed resolution of this Unresolved Safety Issue is under internal review.

Trends In U. S. Nuclear Plant Capacity Factor

International Nuclear Information System (INIS)

Ross, D. F.

1986-01-01

Steam generator tube degradation in pressurized water reactors continues to be a matter of concern. The proposed resolution for this problem was discussed with the commission in September 1984. A letter was issued to PWR licensees in 1985, requesting that the industry describe their overall program for assuring steam generator tube integrity, in order to allow the staff to compare their actions with staff recommendations. The staff report, NUREG-0844, 'NRC Integrated Program for the Resolution of Unresolved Safety Issues A-3, A-4, and A-5 Regarding Steam Generator Tube Integrity,' was issued for public comment. The responses to these items are currently under review by the staff. Three reports on investigations of systems interaction search methods were issued by 1985. These studies complete technical work on the systems interactions issue. The proposed resolution of this Unresolved Safety Issue is under internal review

Identification and communication of uncertainties of phenomenological models in PSA

International Nuclear Information System (INIS)

Pulkkinen, U.; Simola, K.

2001-11-01

This report aims at presenting a view upon uncertainty analysis of phenomenological models with an emphasis on the identification and documentation of various types of uncertainties and assumptions in the modelling of the phenomena. In an uncertainty analysis, it is essential to include and document all unclear issues, in order to obtain a maximal coverage of unresolved issues. This holds independently on their nature or type of the issues. The classification of uncertainties is needed in the decomposition of the problem and it helps in the identification of means for uncertainty reduction. Further, an enhanced documentation serves to evaluate the applicability of the results to various risk-informed applications. (au)

U.S.-China Relations: Policy Issues

Science.gov (United States)

2011-01-12

global issues on which the Obama Administration has sought to work with China are the international financial crisis, climate change, and nuclear non-proliferation. In remarks in July 2009, President Obama declared that partnership between the United States and China was a prerequisite for progress on many of the most pressing global challenges. Continuing major bilateral issues in the relationship include trade and...into the Obama Administration, U.S. officials point to some successes in their efforts to work with China on global issues , including

Glenohumeral abduction contracture in children with unresolved neonatal brachial plexus palsy.

Science.gov (United States)

Eismann, Emily A; Little, Kevin J; Laor, Tal; Cornwall, Roger

2015-01-21

Following neonatal brachial plexus palsy, the Putti sign-obligatory tilt of the scapula with brachiothoracic adduction-suggests the presence of glenohumeral abduction contracture. In the present study, we utilized magnetic resonance imaging (MRI) to quantify this glenohumeral abduction contracture and evaluate its relationship to shoulder joint deformity, muscle atrophy, and function. We retrospectively reviewed MRIs of the thorax and shoulders obtained before and after shoulder rebalancing surgery (internal rotation contracture release and external rotation tendon transfer) for twenty-eight children with unresolved neonatal brachial plexus palsy. Two raters measured the coronal positions of the scapula, thoracic spine, and humeral shaft bilaterally on coronal images, correcting trigonometrically for scapular protraction on axial images. Supraspinatus, deltoid, and latissimus dorsi muscle atrophy was assessed, blinded to other measures. Correlations between glenohumeral abduction contracture and glenoid version, humeral head subluxation, passive external rotation, and Mallet shoulder function before and after surgery were performed. MRI measurements were highly reliable between raters. Glenohumeral abduction contractures were present in twenty-five of twenty-eight patients, averaging 33° (range, 10° to 65°). Among those patients, abductor atrophy was present in twenty-three of twenty-five, with adductor atrophy in twelve of twenty-five. Preoperatively, greater abduction contracture severity correlated with greater Mallet global abduction and hand-to-neck function. Abduction contracture severity did not correlate preoperatively with axial measurements of glenohumeral dysplasia, but greater glenoid retroversion was associated with worse abduction contractures postoperatively. Surgery improved passive external rotation, active abduction, and hand-to-neck function, but did not change the abduction contracture. A majority of patients with persistent shoulder weakness

Forensic, Cultural, and Systems Issues in Child Sexual Abuse Cases--Part 2: Research and Practitioner Issues

Science.gov (United States)

Tishelman, Amy C.; Geffner, Robert

2010-01-01

This article introduces the second issue of the special double issue focusing on forensic, cultural, and systems issues in child sexual abuse cases. We briefly review the articles, which include a discussion of child sexual abuse myths, an empirical analysis of extended child sexual abuse evaluations, an article on the role of the medical provider…

Unresolved Ethnic Conflict and Religious Revival in Russia: The Chechen Element

National Research Council Canada - National Science Library

Mitchell, Shenequa L

2007-01-01

As social, cultural and political issues have resurfaced between contemporary ethnic Russians and members of the Northern Caucasus-Chechen minority group, this centuries-old-ethnic-conflict continues...

The Effect of the Global Financial Crisis and the Sovereign Debt Crisis on Public Sector Accounting: A Contextual Analysis

OpenAIRE

Emmanuel Igbawase Abanyam; Paul Aondona Angahar

2015-01-01

This paper examines the effect of global financial crisis and the sovereign debt crisis on public sector accounting. The global financial crisis and sovereign debt crisis were contextually analysed bringing out clearly its effect on public sector accounting which include accounting issues related to public sector intervention, accounting for recapitalization of investment, accounting for fiscal support, accounting for financial guarantees. The paper found out that, the unresolved fiscal and d...

Molecular phylogeny of Subtribe Artemisiinae (Asteraceae), including Artemisia and its allied and segregate genera

Science.gov (United States)

Watson, Linda E; Bates, Paul L; Evans, Timothy M; Unwin, Matthew M; Estes, James R

2002-01-01

Background Subtribe Artemisiinae of Tribe Anthemideae (Asteraceae) is composed of 18 largely Asian genera that include the sagebrushes and mugworts. The subtribe includes the large cosmopolitan, wind-pollinated genus Artemisia, as well as several smaller genera and Seriphidium, that altogether comprise the Artemisia-group. Circumscription and taxonomic boundaries of Artemisia and the placements of these small segregate genera is currently unresolved. Results We constructed a molecular phylogeny for the subtribe using the internal transcribed spacers (ITS) of nuclear ribosomal DNA analyzed with parsimony, likelihood, and Bayesian criteria. The resulting tree is comprised of three major clades that correspond to the radiate genera (e.g., Arctanthemum and Dendranthema), and two clades of Artemisia species. All three clades have allied and segregate genera embedded within each. Conclusions The data support a broad concept of Artemisia s.l. that includes Neopallasia, Crossostephium, Filifolium, Seriphidium, and Sphaeromeria. However, the phylogeny excludes Elachanthemum, Kaschgaria, and Stilnolepis from the Artemisia-group. Additionally, the monophyly of the four subgenera of Artemisia is also not supported, with the exception of subg. Dracunculus. Homogamous, discoid capitula appear to have arisen in parallel four to seven times, with the loss of ray florets. Thus capitular morphology is not a reliable taxonomic character, which traditionally has been one of the defining characters. PMID:12350234

Cross-section fluctuations and self-shielding effects in the unresolved resonance region - International Evaluation Co-operation volume 15

International Nuclear Information System (INIS)

Froehner, F.H.; Larson, Duane C.; Tagesen, Siegfried; Petrizzi, Luigi; Hasegawa, Akira; Nakagawa, Tsuneo; Hogenbirk, Alfred; Weigmann, H.

1995-01-01

A Working Party on International Evaluation Co-operation was established under the sponsorship of the OECD/NEA Nuclear Science Committee (NSC) to promote the exchange of information on nuclear data evaluations, validation, and related topics. Its aim is also to provide a framework for co-operative activities between members of the major nuclear data evaluation projects. This includes the possible exchange of scientists in order to encourage co-operation. Requirements for experimental data resulting from this activity are compiled. The Working Party determines common criteria for evaluated nuclear data files with a view to assessing and improving the quality and completeness of evaluated data. The Parties to the project are: ENDF (United States), JEFF/EFF (NEA Data Bank Member countries), and JENDL (Japan). Co-operation with evaluation projects of non-OECD countries are organised through the Nuclear Data Section of the International Atomic Energy Agency (IAEA). NEA/NSC Subgroup 15 has had the task to assess self-shielding effects in the unresolved resonance range of structural materials, in particular their importance at various energies, and possible ways to deal with them in shielding and activation work. The principal results achieved are summarised briefly, in particular: - New data base consisting of high-resolution transmission data measured at Oak Ridge and Geel; - Improved theoretical understanding of cross-section fluctuations, including their prediction, that has been derived from the Hauser-Feshbach theory; - Benchmark results on the importance of self-shielding in iron at various energies; - Consequences for information storage in evaluated nuclear data files; - Practical utilisation of self-shielding information from evaluated files. Benchmark results as well as the Hauser-Feshbach theory show that self-shielding effects are important up to a 4-or 5-MeV neutron energy. Fluctuation factors extracted from high-resolution total cross-section data can be

Radical SAM, A Novel Protein Superfamily Linking Unresolved Steps in Familiar Biosynthetic Pathways with Radical Mechanisms: Functional Characterization Using New Analysis and Information Visualization Methods

Energy Technology Data Exchange (ETDEWEB)

Sofia, Heidi J.; Chen, Guang; Hetzler, Elizabeth G.; Reyes Spindola, Jorge F.; Miller, Nancy E.

2001-03-01

A large protein superfamily with over 500 members has been discovered and analyzed using powerful new bioinformatics and information visualization methods. Evidence exists that these proteins generate a 5?-deoxyadenosyl radical by reductive cleavage of S-adenosylmethionine (SAM) through an unusual Fe-S center. Radical SAM superfamily proteins function in DNA precursor, vitamin, cofactor, antibiotic, and herbicide biosynthesis in a collection of basic and familiar pathways. One of the members is interferon-inducible and is considered a candidate drug target for osteoporosis. The identification of this superfamily suggests that radical-based catalysis is important in a number of previously well-studied but unresolved biochemical pathways.

Sanskrit Issue.

Science.gov (United States)

Miller, Barbara Stoler, Ed.

1971-01-01

This issue of "Mahfil" is devoted to Sanskrit literature and contains a note on Sanskrit pronunciation and selections of Sanskrit literature. It also contains articles analyzing and discussing various aspects of the literature, including "Sanskrit Rhetoric and Poetic,""The Creative Role of the Goddess Vac in the…

A first course in topos quantum theory

International Nuclear Information System (INIS)

Flori, Cecilia

2013-01-01

Written by a leading researcher in the field. Concise course-tested textbook. Includes worked-out problems In the last five decades various attempts to formulate theories of quantum gravity have been made, but none has fully succeeded in becoming the quantum theory of gravity. One possible explanation for this failure might be the unresolved fundamental issues in quantum theory as it stands now. Indeed, most approaches to quantum gravity adopt standard quantum theory as their starting point, with the hope that the theory's unresolved issues will get solved along the way. However, these fundamental issues may need to be solved before attempting to define a quantum theory of gravity. The present text adopts this point of view, addressing the following basic questions: What are the main conceptual issues in quantum theory? How can these issues be solved within a new theoretical framework of quantum theory? A possible way to overcome critical issues in present-day quantum physics - such as a priori assumptions about space and time that are not compatible with a theory of quantum gravity, and the impossibility of talking about systems without reference to an external observer - is through a reformulation of quantum theory in terms of a different mathematical framework called topos theory. This course-tested primer sets out to explain to graduate students and newcomers to the field alike, the reasons for choosing topos theory to resolve the above-mentioned issues and how it brings quantum physics back to looking more like a ''neo-realist'' classical physics theory again.

Male Fertility Issues

Science.gov (United States)

Fertility issues are common in boys and men getting cancer treatment. Fertility preservation options include sperm banking, testicular shielding, testicular sperm extraction (TESE), and testicular tissue freezing. Support and clinical trials are listed.

Cross-cultural Manifestations of Gender Conflict: The African ...

African Journals Online (AJOL)

In both national and international fora, gender issues have generated the most heated and controversial debates, yet, the issue of gender conflict still remains largely unresolved. Existing alternatives reflect unending debates that provide answers to the vexed issue of gender misunderstanding. At the heart of the matter is ...

An Overview of Residential Ventilation Activities in the Building America Program (Phase I)

Energy Technology Data Exchange (ETDEWEB)

Barley, D.

2001-05-21

This report provides an overview of issues involved in residential ventilation; provides an overview of the various ventilation strategies being evaluated by the five teams, or consortia, currently involved in the Building America Program; and identifies unresolved technical issues.

Essential 'ways-of-working' features of 'configuration management for new-build 2011' and 'issue-resolved replication'

International Nuclear Information System (INIS)

Schneider, B.

2011-01-01

The 'Ways-of-Working Foundation' of the Competencies most vital to 'New-Build' are provided. Examples are provided of local CM disasters and I-R.R success stories from else-where. [Configuration Management for New-Build 2011 - State-of-Art Specifications at Every Level - driven by Best-Available OpEx - based on SofA Expertise - subjected to Transparent, Independent Review]. It is the position of CMC2011 that weak CM is at the root of much 'less-than-adequate performance' (especially refurb programs - since ∼1986). For New-Build, the 'Foundation' of Configuration-Management is 'State-of-Art Specifications for All Systems, Equipment, Materials, and Processes' - supported by 'State-of-Art Service-Provider Expertise' - and Audit-able via 'Transparent, Third-Party, Issue-Review-and-Resolution Programs'. CM must be executed by the Architecture-Service-Providers - but it must be demanded by the Utility-Owners. [Issue-Resolved, Configuration-Managed, Replication - Rigorous, Configuration-Managed Replication for the Capture of the 85% that is Proven - plus - Parallel, Transparent, Separately-Managed, Contractually-Facilitated, Side-Stream Programs for the Identification and Resolution of the highly-troublesome 15% that remains Un-Resolved]. For New-Build in 2011, as well as for Refurb and Ops/Outage Support at any time, the last thing the Owner-Utilities want is innovation - or invention - or anything else for which substantial operating-experience and reliability-verification cannot be provided. I-R.R is discussed as - i) 'Rigorous Replication' and ii) 'Issue-Identification and Resolution'. What we refer to as 'Side-Stream, Independently-Driven, Issue-Identification and Resolution' is already practiced by utility 'SIR Teams' - i.e. - 'go-anywhere, do-anything, flying-squads' - for whom the watch-word is 'expect the un-anticipated'. Issue-Resolution must be provided as part of every project. It must be demanded (and contractually-facilitated) up-front by the Utility

Year 2000 commercial issues

International Nuclear Information System (INIS)

Kratz, M.P.J.; Booth, R.T.

1998-01-01

This presentation focused on commercial aspects of the Y2K including: (1) special communication issues, (2) outsourcing transactions, (3) joint ventures and the significance for the oil and gas industry, and (4) contingency planning. Communication issues involve interaction with suppliers and vendors of critical systems, liability for Y2K communications (misrepresentation, defamation, promissory estoppel, statutory liability), securities disclosure (Canadian and US SEC requirements), protected communications, protection for Year 2000 statements. Outsourcing problems highlighted include resistance of suppliers to assume responsibility for Y2K problem remediation, factors which support and negate supplier responsibility, scope of suppliers' obligation, and warranties in respect of third party software. Regarding joint ventures, questions concerning limitations on liability, supply warranties, stand-by arrangements, stockpiling inventory, indemnities, confidentiality, operator compensation versus operator risk, and insurance were raised and addressed. Among contingency planning issues the questions of Y2K legal audit, and disclosure aspects of contingency planning were the featured concerns. figs

Year 2000 commercial issues

Energy Technology Data Exchange (ETDEWEB)

Kratz, M.P.J.; Booth, R.T. [Bennett Jones, Calgary, AB (Canada)

1998-12-31

This presentation focused on commercial aspects of the Y2K including: (1) special communication issues, (2) outsourcing transactions, (3) joint ventures and the significance for the oil and gas industry, and (4) contingency planning. Communication issues involve interaction with suppliers and vendors of critical systems, liability for Y2K communications (misrepresentation, defamation, promissory estoppel, statutory liability), securities disclosure (Canadian and US SEC requirements), protected communications, protection for Year 2000 statements. Outsourcing problems highlighted include resistance of suppliers to assume responsibility for Y2K problem remediation, factors which support and negate supplier responsibility, scope of suppliers` obligation, and warranties in respect of third party software. Regarding joint ventures, questions concerning limitations on liability, supply warranties, stand-by arrangements, stockpiling inventory, indemnities, confidentiality, operator compensation versus operator risk, and insurance were raised and addressed. Among contingency planning issues the questions of Y2K legal audit, and disclosure aspects of contingency planning were the featured concerns. figs.

Beyond discovery: A review of the critique of the discovery view of opportunities

DEFF Research Database (Denmark)

Korsgaard, Steffen T.

This paper systematically reviews and synthesises the critique since 2000 of the discovery view's interpretation of entrepreneurial opportunities. The review shows that the framing of the debate as polarised between two oppositions, the discovery view versus the creation view, is oversimplified....... The issue of whether opportunities are discovered or created is simply one of several key issues in play in the debate. These key issues include questions concerning agency, process, and the role of subjectivity, creativity and interpretation. Propositions for future research are developed from the critique......, emphasising distributed agency, non-linear processes, opportunities as formed, and the role of creativity. However, the paper also points to unresolved issues in relation to all four propositions that require further empirical and conceptual work....

DNA Sequence Analyses Reveal Abundant Diversity, Endemism and Evidence for Asian Origin of the Porcini Mushrooms

OpenAIRE

Feng, Bang; Xu, Jianping; Wu, Gang; Zeng, Nian-Kai; Li, Yan-Chun; Tolgor, Bau; Kost, Gerhard W.; Yang, Zhu L.

2012-01-01

The wild gourmet mushroom Boletus edulis and its close allies are of significant ecological and economic importance. They are found throughout the Northern Hemisphere, but despite their ubiquity there are still many unresolved issues with regard to the taxonomy, systematics and biogeography of this group of mushrooms. Most phylogenetic studies of Boletus so far have characterized samples from North America and Europe and little information is available on samples from other areas, including t...

Autosomal-dominant GTPCH1-deficient DRD: clinical characteristics and long-term outcome of 34 patients

OpenAIRE

Trender-Gerhard , Iris; Sweeney , Mary G; Schwingenschuh , Petra; Mir , Pablo; Edwards , Mark J; Gerhard , Alexander; Polke , James M; Hanna , Mike G; Davis , Mary B; Wood , Nick W; Bhatia , Kailash P

2009-01-01

Abstract An autosomal dominantly inherited defect in the GCH1 gene that encodes guanosine triphosphate cyclohydrolase 1 (GTPCH1) is the most common cause of dopa-responsive dystonia (DRD). A classic phenotype of young-onset lower limb dystonia, diurnal fluctuations, and excellent response to levodopa has been well recognized in association with GCH1 mutations, and rare atypical presentations have been reported. However, a number of clinical issues remain unresolved including phenot...

The ethnic composition of the neighbourhood and ethnic minorities' social contacts: three unresolved issues

OpenAIRE

Flap, H.D.; Dagevos, J.J.; Vervoort, M.

2010-01-01

It is frequently supposed that the ethnic composition of a neighbourhood affects ethnic minorities’ social contacts with natives, co-ethnics and other ethnic minorities. Research to date, however, falls short in several ways. First of all, previous studies often did not consider social contacts with co-ethnics and other ethnic minorities. Second, although different mechanisms (i.e. meeting opportunities, ethnic competition theory, ‘third parties’ and constrict theory) point to different dimen...

The ethnic composition of the neighbourhood and ethnic minorities' social contacts : three unresolved issues

NARCIS (Netherlands)

Flap, H.D.; Dagevos, J.J.; Vervoort, M.

2010-01-01

It is frequently supposed that the ethnic composition of a neighbourhood affects ethnic minorities’ social contacts with natives, co-ethnics and other ethnic minorities. Research to date, however, falls short in several ways. First of all, previous studies often did not consider social contacts with

Family Interaction in the Newborn Period: Some Findings, Some Observations, and Some Unresolved Issues.

Science.gov (United States)

Parke, Ross D.

This paper presents two studies which explored the manner in which the father interacts with his newborn infant and compared paternal and maternal interaction patterns. In contrast to earlier studies, a direct observational approach was employed that permitted a detailed specification of father behaviors in the presence of the newborn. In the…

Seismic qualification of equipment in operating nuclear power plants: Unresolved Safety Issue A-46

International Nuclear Information System (INIS)

Chang, T.Y.

1987-02-01

The margin of safety provided in existing nuclear power plant equipment to resist seismically induced loads and perform their intended safety functions may vary considerably, because of significant changes in design criteria and methods for the seismic qualification of equipment over the years. Therefore, the seismic qualification of equipment in operating plants must be reassessed to determine whether requalification is necessary. The objective of technical studies performed under the Task Action Plan A-46 was to establish an explicit set of guidelines and acceptance criteria to judge the adequacy of equipment under seismic loading at all operating plants, in lieu of requiring qualification to the current criteria that are applied to new plants. This report summarizes the work accomplished on USI A-46. In addition, the collection and review of seismic experience data and existing seismic test data are presented. Staff assessment of work accomplished under USI A-46 leads to the conclusion that the use of seismic experience data provides the most reasonable alternative to current qualification criteria. Consideration of seismic qualification by use of experience data was a specific task in USI A-46. Several other A-46 tasks serve to support the use of an experienced data base. The principal technical finding of USI A-46 is that seismic experience data, supplemented by existing seismic test data, applied in accordance with the guidelines developed, can be used to verify the seismic adequacy of mechanical and electrical equipment in operating nuclear plants. Explicit seismic qualification should be required only if seismic experience data or existing test data on similar components cannot be shown to apply

Editorial Volume 4 Issue 3

Directory of Open Access Journals (Sweden)

Ciorstan J. Smark

2010-09-01

Full Text Available This issue of AABFJ presents papers from a range of approaches and research topics in keeping with thejournal’s broad focus on accounting, finance and business. This issue includes the examination of microstructurefinance in the context of real estate pricing and an analysis straddling financial analysis and the roleof accounting standards in decision-making. The policing paper in accounting employs a socialconstructionist approach to the study of the New Zealand public sector. Business education is represented ina study of students undertaking internships as part of their university degree in commerce. In the last issue,the editors flagged the move to broaden the scope of the journal to include shorter articles and book reviews.This issue presents the first book review. Readers will no doubt notice that the printable Research Onlineformat has returned to A4. In an environment of resource constraints, both financially and environmentally,the editors decided that the revised format is more appropriate. As usual, electronic media is the mostprevalent mode of delivery.This

Public Energy Education: Issues for Discussion. Draft.

Science.gov (United States)

Public Energy Education Task Force.

This paper was intended to stimulate discussion of energy education issues at a conference on energy issues. The discussion ranges through numerous topics at issue in energy education including public energy awareness, definition of public education, the distinction between public education and public relations, and the presentation of a model…

Fusion Canada issue 15

International Nuclear Information System (INIS)

1991-10-01

A short bulletin from the National Fusion Program. Included in this issue is a report on the 1996 IAEA Fusion Conference site, operations at the Tokamak de Varennes including divertor pumping of impurities and pumping of carbon monoxide and methane, a discussion of the CFFTP and it's role. 1 fig

Fusion Canada issue 15

Energy Technology Data Exchange (ETDEWEB)

NONE

1991-10-01

A short bulletin from the National Fusion Program. Included in this issue is a report on the 1996 IAEA Fusion Conference site, operations at the Tokamak de Varennes including divertor pumping of impurities and pumping of carbon monoxide and methane, a discussion of the CFFTP and it`s role. 1 fig.

Robustness-related issues in speaker recognition

CERN Document Server

Zheng, Thomas Fang

2017-01-01

This book presents an overview of speaker recognition technologies with an emphasis on dealing with robustness issues. Firstly, the book gives an overview of speaker recognition, such as the basic system framework, categories under different criteria, performance evaluation and its development history. Secondly, with regard to robustness issues, the book presents three categories, including environment-related issues, speaker-related issues and application-oriented issues. For each category, the book describes the current hot topics, existing technologies, and potential research focuses in the future. The book is a useful reference book and self-learning guide for early researchers working in the field of robust speech recognition.

Chronic toxicity of unresolved complex mixtures (UCM) of hydrocarbons in marine sediments

Energy Technology Data Exchange (ETDEWEB)

Scarlett, A.; Galloway, T.S. [Plymouth Univ., Drake Circus (United Kingdom). School of Biological Sciences; Rowland, S.J. [Plymouth Univ., Drake Circus (United Kingdom). School of Earth, Ocean and Environmental Sciences

2007-08-15

Background, Aim and Scope: Unresolved complex mixtures (UCM) of hydrocarbons, containing many thousands of compounds which cannot be resolved by conventional gas chromatography (GC), are common contaminants of sediments but little is known of their potential to affect sediment-dwelling organisms. Evidence exists for reduced health status in mussels, arising from aqueous exposure to aromatic UCM components acting through a narcotic mode of action. However, UCM contaminants in sediments may not be sufficiently bioavailable to elicit toxic effects. The aim of our study was therefore to measure the sublethal effects of chronic exposure to model UCM-dominated oils at environmentally realistic concentrations and compare this to effects produced by a UCM containing weathered crude oil. A further aim was to determine which, if any, fractions of the oils were responsible for any observed toxicity. Materials and Methods: Whole oils were spiked into estuarine sediment to give nominal concentrations of 500 {mu}g g-1 dry weight. Juveniles of the estuarine amphipod Corophium volutator were exposed to the contaminated sediment for 35 days and their survival, growth rate and reproductive success quantified. Using an effect-directed fractionation approach, the oils were fractionated into aliphatic and two aromatic fractions by open column chromatography and their toxicity assessed by further chronic exposures using juvenile C. volutator. Results: The growth rates of amphipods were reduced following exposure to the oils although this was only statistically significant for the weathered oil; reproductive success was reduced by all oil exposures. Sediment spiked with UCM fractions also caused reduced growth and reproduction but no particular fraction was found to be responsible for the observed toxicity. Survivorship was not affected by any oil or fraction. Discussion: The study showed that chronic exposure to sediments contaminated by UCM-dominated oils could have population level

Perspectives: Using Historical Documents To Think about NIF Issues.

Science.gov (United States)

National Archives and Records Service (GSA), Washington, DC.

The purpose of using historical documents in the classroom is to generate and enhance discussion by providing a historical perspective for issues. Five documents are included in this packet and are to be used as a supplemental material for the National Issues Forum (NIF) topics. Issues raised include (1) an analysis of the documents and (2)…

Strategic Issues for Training.

Science.gov (United States)

Pollitt, David, Ed.

1999-01-01

Contains precis of 18 articles on strategic management issues, including management development, on-the-job training, corporate scholarship, educational technology, coaching, investing in intellectual capital, and knowledge management. (SK)

Current and emerging occupational safety and health (OSH) issues in the healthcare sector, including home and community care

NARCIS (Netherlands)

Jong, T. de; Bos, E.; Pawlowska-Cyprysiak, K.; Hildt-Ciupinska, K.; Malinska, M.; Nicolescu, G.; Trifu, A.

2014-01-01

This report gives an overview of the current and emerging OSH issues for health- and social care workers and how these affect their safety and health at work and influence the quality of care they provide. It combines a literature review and the responses received to a questionnaire sent to OSH

Nuclear power plant safety related pump issues

Energy Technology Data Exchange (ETDEWEB)

Colaccino, J.

1996-12-01

This paper summarizes of a number of pump issues raised since the Third NRC/ASME Symposium on Valve and Pump Testing in 1994. General issues discussed include revision of NRC Inspection Procedure 73756, issuance of NRC Information Notice 95-08 on ultrasonic flow meter uncertainties, relief requests for tests that are determined by the licensee to be impractical, and items in the ASME OM-1995 Code, Subsection ISTB, for pumps. The paper also discusses current pump vibration issues encountered in relief requests and plant inspections - which include smooth running pumps, absolute vibration limits, and vertical centrifugal pump vibration measurement requirements. Two pump scope issues involving boiling water reactor waterlog and reactor core isolation cooling pumps are also discussed. Where appropriate, NRC guidance is discussed.

Nuclear power plant safety related pump issues

International Nuclear Information System (INIS)

Colaccino, J.

1996-01-01

This paper summarizes of a number of pump issues raised since the Third NRC/ASME Symposium on Valve and Pump Testing in 1994. General issues discussed include revision of NRC Inspection Procedure 73756, issuance of NRC Information Notice 95-08 on ultrasonic flow meter uncertainties, relief requests for tests that are determined by the licensee to be impractical, and items in the ASME OM-1995 Code, Subsection ISTB, for pumps. The paper also discusses current pump vibration issues encountered in relief requests and plant inspections - which include smooth running pumps, absolute vibration limits, and vertical centrifugal pump vibration measurement requirements. Two pump scope issues involving boiling water reactor waterlog and reactor core isolation cooling pumps are also discussed. Where appropriate, NRC guidance is discussed

Development of a comprehensive survey of sexuality issues including a self-report version of the International Spinal Cord Injury sexual function basic data sets.

Science.gov (United States)

New, P W; Currie, K E

2016-08-01

Questionnaire development, validation and completion. Develop comprehensive survey of sexuality issues including validated self-report versions of the International Spinal Cord Injury male sexual function and female sexual and reproductive function basic data sets (SR-iSCI-sexual function). People with spinal cord damage (SCD) living in the community, Australia from August 2013 to June 2014. An iterative process involving rehabilitation medicine clinicians, a nurse specialising in sexuality issues in SCD and people with SCD who developed a comprehensive survey that included the SR-iSCI-sexual function. Participants recruitment through spinal rehabilitation review clinic and community organisations that support people with SCD. Surveys completed by 154 people. Most were male (n=101, 65.6%). Respondents' median age was 50 years (interquartile range (IQR) 38-58), and they were a median of 10 years (IQR 4-20) after the onset of SCD. Sexual problems unrelated to SCD were reported by 12 (8%) respondents, and 114 (n=75.5%) reported sexual problems because of SCD. Orgasms were much less likely (χ(2)=13.1, P=0.006) to be normal in males (n=5, 5%) compared with females (n=11, 22%). Males had significantly worse (χ(2)=26.0, P=0.001) psychogenic genital functioning (normal n=9, 9%) than females (normal n=13, 26%) and worse (χ(2)=10.8, P=0.013) reflex genital functioning. Normal ejaculation was reported in only three (3%) men. Most (n=26, 52%) women reported reduced or absent menstruation pattern since SCD. The SR-iSCI-sexual function provides a useful tool for researchers and clinicians to collect information regarding patient-reported sexual functioning after SCD and to facilitate comparative studies.

Interactions of relativistic heavy ions in thick heavy element targets and some unresolved problems

International Nuclear Information System (INIS)

Brandt, R.; Ditlov, V.A.; Pozharova, E.A.; Smirnitskij, V.A.

2005-01-01

Interactions of relativistic heavy ions with total energies above 30 GeV in thick Cu and Pb targets (≥2 cm) have been studied with various techniques. Radiochemical irradiation experiments using thick Cu targets, both in a compact form or as diluted '2π-Cu targets' have been carried out with several relativistic heavy ions, such as 44 GeV 12 C (JINR, Dubna) and 72 GeV 40 Ar (LBL, Berkeley, USA). Neutron measuring experiments using thick targets irradiated with various relativistic heavy ions up to 44 GeV 12 C have been performed at JINR. In addition, the number of 'black prongs' in nuclear interactions (due to protons with energies less than 30 MeV and emitted from the target-like interaction partner at rest) produced with 72 GeV 22 Ne ions in nuclear emulsion plates has been measured in the first nuclear interaction of the primary 22 Ne ion and in the following second nuclear interaction of the secondary heavy (Z>1) ion. Some essential results have been obtained. 1) Spallation products produced by relativistic secondary fragments in interactions ([44 GeV 12 C or 72 GeV 40 Ar]+Cu) within thick copper yield less products close to the target and much more products far away from the target as compared to primary beam interactions. This applies also to secondary particles emitted into large angles (Θ>10deg). 2) The neutron production of 44 GeV 12 C within thick Cu and Pb targets is beyond the estimated yield as based on experiments with 12 GeV 12 C. These rather independent experimental results cannot be understood with well-accepted nuclear reaction models. They appear to present unresolved problems

Fusion Canada issue 4

International Nuclear Information System (INIS)

1988-05-01

A short bulletin from the National Fusion Program. Included in this issue is a technical update on Tokamak de Varennes, a report on the Beatrix II Breeding Materials Test Program, the Tritium glovebox system for UPM, Saudi Arabia, a broad update of the Canadian Fusion Fuels Technology Project is also included. 1 fig

Fusion Canada issue 4

Energy Technology Data Exchange (ETDEWEB)

NONE

1988-05-01

A short bulletin from the National Fusion Program. Included in this issue is a technical update on Tokamak de Varennes, a report on the Beatrix II Breeding Materials Test Program, the Tritium glovebox system for UPM, Saudi Arabia, a broad update of the Canadian Fusion Fuels Technology Project is also included. 1 fig.

Special Issue: Candida and Candidiasis

Directory of Open Access Journals (Sweden)

Jeniel E. Nett

2018-06-01

Full Text Available This special issue highlights emerging topics related to Candida, the most prevalent fungal pathogen in the hospital setting. The advantages and limitations of new, non-culture based diagnostic techniques are discussed. The issue reviews mammalian and non-mammalian infection models. The manuscripts present updates on several molecular mechanisms of pathogenicity, including filamentation, biofilm formation, and phospholipid production.

Chemical countermeasures: Dispersants overview of dispersant use (including application) and research issues

International Nuclear Information System (INIS)

Butler, J.N.

1992-01-01

I will attempt in twenty minutes to summarize the state of research on oil spill dispersants as I perceive it. The expertise I bring to this task includes 20 years of experience with the fate and effects of petroleum in the marine environment, including participation in the 1973 and 1981 NRC studies and three years as chairman of the NRC committee on oil spill dispersants. I More recently I served on a committee of the International Maritime Organization which reviewed the open-quotes Impact of oil and related chemicals and wastes on the marine environment.close quotes That report will be published this year. However, my statements in this paper are not made as a representative of either NRC or IMO. They are my own interpretation of scientific literature cited in the above reviews. Dispersants are chemical formulations, which include surface active agents, designed to decrease the interfacial tension between oil and water. Because the first attempts to disperse oil on a large scale, at the Torrey Canyon spill of 1967, used highly toxic degreasing agents, dispersants have an undeserved reputation for toxicity. In fact, for twenty years dispersant formulations have been developed with an emphasis on reducing their toxicity to marine life. The dispersal of oil in water has been documented in the laboratory by dozens of papers (see references in NRC 1989, pp 70-79), and in the field by dozens of studies (NRC 1989, pp 165- 193). The toxicity of commercial dispersant formulations (NRC 1989, pp 81-123) and dispersed oil (NRC 1989, pp 123-147) has been tested on a wide variety of marine organisms ranging from algae to salmonid fishes. The NRC review has been updated by the IMO/GESAMP (1992) study, but the conclusions remain unchanged

Integrative therapies for low back pain that include complementary and alternative medicine care: a systematic review.

Science.gov (United States)

Kizhakkeveettil, Anupama; Rose, Kevin; Kadar, Gena E

2014-09-01

Systematic review of the literature. To evaluate whether an integrated approach that includes different Complementary and Alternative Medicine (CAM) therapies combined or CAM therapies combined with conventional medical care is more effective for the management of low back pain (LBP) than single modalities alone. LBP is one of the leading causes of disability worldwide, yet its optimal management is still unresolved. The PRISMA Statement guidelines were followed. The Cochrane Back Review Group scale was used to rate the quality of the studies found. Twenty-one studies were found that met the inclusion criteria. The CAM modalities used in the studies included spinal manipulative therapy, acupuncture, exercise therapy, physiotherapy, massage therapy, and a topical ointment. Twenty studies included acupuncture and/or spinal manipulative therapy. Nine high quality studies showed that integrative care was clinically effective for the management of LBP. Spinal manipulative therapy combined with exercise therapy and acupuncture combined with conventional medical care or with exercise therapy appears to be promising approaches to the management of chronic cases of LBP. There is support in the literature for integrated CAM and conventional medical therapy for the management of chronic LBP. Further research into the integrated management of LBP is clearly needed to provide better guidance for patients and clinicians.

Export market potential for Alaskan and Western US coals

International Nuclear Information System (INIS)

Sims, J.

1992-01-01

Major utilization trends may create opportunity for dramatic expansion of Alaska's coal exports from a huge ultra-low sulfur coal resource base. Markets are expected to open up in the Pacific Basin for sub-bituminous and bituminous steam coals from Alaska to include not only run-of-mine coals but also product streams from beneficiation technologies. Market considerations aside, deficiencies in physical infrastructure and an unresolved resource ownership issue are the principal impediments at this time to property development

Kohlberg and Gilligan: Duet or Duel?

Science.gov (United States)

Jorgensen, Gunnar

2006-01-01

Most moral psychologists have come to accept two types of moral reasoning: Kohlberg's "justice" and Gilligan's "care", but there still seem to be some unresolved issues. By analysing and comparing Kohlberg's statement on some theoretical issues with some of Gilligan's statements in an interview in April 2003, I will look at some key issues in the…

Family Issues in Multigenerational Households.

Science.gov (United States)

Feinauer, Leslie L; And Others

1987-01-01

Studied issues faced by multigenerational families and their implications for family therapy. Major factors in multigenerational households included dependency, sibling relationships, depression, and demanding and egocentric behavior. Factors to consider during family therapy include respite care, age, interdependence, dignity, provision of care,…

Resolution of the Task A-11 reactor-vessel materials-toughness safety issue. Appendices C-K

International Nuclear Information System (INIS)

1982-10-01

The central problem in the unresolved safety issue A-11, Reactor Vessel Materials Toughness, was to provide guidance in performing analyses required by 10 CFR Part 50, Appendix G, Section V.C. for reactor pressure vessels (RPVs) which fail to meet the toughness requirement during service life as a result of neutron radiation embrittlement. Although the methods of linear-elastic fracture mechanics (LEFM) were adequate for low-temperature RPV problems, they were inapplicable under operating conditions because vessel steels, even those which exhibit less than 50 ft-lb of C/sub v/ energy, were relatively tough at temperatures where the impact energy reached its upper shelf values. A technical team of recognized experts was organized to assist the NRC staff in addressing the problem. Using the foundation of the tearing modulus concept, which had been developed under earlier NRC sponsorship, relationships were obtained which provided approximate solutions to the problem of RPV fracture with assumed beltline region flaws. The first paper of this report is a summary of the problem, the solutions, and the results of verification analyses. The details are provided in a series of appendices in Volumes I and II

Special issue on network coding

Science.gov (United States)

Monteiro, Francisco A.; Burr, Alister; Chatzigeorgiou, Ioannis; Hollanti, Camilla; Krikidis, Ioannis; Seferoglu, Hulya; Skachek, Vitaly

2017-12-01

Future networks are expected to depart from traditional routing schemes in order to embrace network coding (NC)-based schemes. These have created a lot of interest both in academia and industry in recent years. Under the NC paradigm, symbols are transported through the network by combining several information streams originating from the same or different sources. This special issue contains thirteen papers, some dealing with design aspects of NC and related concepts (e.g., fountain codes) and some showcasing the application of NC to new services and technologies, such as data multi-view streaming of video or underwater sensor networks. One can find papers that show how NC turns data transmission more robust to packet losses, faster to decode, and more resilient to network changes, such as dynamic topologies and different user options, and how NC can improve the overall throughput. This issue also includes papers showing that NC principles can be used at different layers of the networks (including the physical layer) and how the same fundamental principles can lead to new distributed storage systems. Some of the papers in this issue have a theoretical nature, including code design, while others describe hardware testbeds and prototypes.

The future of nuclear power after Sizewell B. 3 v.: v. 1 Economic issues; v. 2 Environmental and safety issues; v. 3 Public perception issues

International Nuclear Information System (INIS)

1987-01-01

The three days of conference proceedings are published in three separate volumes. The first includes 7 papers relating to economic issues - those presented at the Sizewell-B public inquiry and the changes in the economic situation since the inquiry ended. The electricity demand, how this demand is to be met by nuclear and other fuel sources and how energy conservation might be an economic alternative to simply building more generating capacity are all issues discussed. The possible privatisation of the industry is also touched on. Volume two has 8 papers concerned with environmental and safety issues. These include the influence of the Sizewell-B decision on nuclear licensing and reactor safety, the technical and safety aspects of pressurized water reactors (PWR), the roles of British Nuclear Fuels and the United Kingdom Atomic Energy Authority, and radiation protection and effluent discharge control. The six papers in volume 3 look at public perception issues - not only towards nuclear power but towards the public inquiry process. The local authority view, the Friends of the Earth case against the PWR, and technical expertise in the decision process are also topics covered. All the papers are indexed separately. (UK)

URR [Unresolved Resonance Region] computer code: A code to calculate resonance neutron cross-section probability tables, Bondarenko self-shielding factors, and self-indication ratios for fissile and fertile nuclides

International Nuclear Information System (INIS)

Leal, L.C.; de Saussure, G.; Perez, R.B.

1990-01-01

The URR computer code has been developed to calculate cross-section probability tables, Bondarenko self-shielding factors, and self-indication ratios for fertile and fissile isotopes in the unresolved resonance region. Monte Carlo methods are utilized to select appropriate resonance parameters and to compute the cross sections at the desired reference energy. The neutron cross sections are calculated by the single-level Breit-Wigner formalism with s-, p-, and d-wave contributions. The cross-section probability tables are constructed by sampling by Doppler broadened cross-sections. The various self-shielding factors are computer numerically as Lebesgue integrals over the cross-section probability tables

Issues in Electronic Publishing.

Science.gov (United States)

Meadow, Charles T.

1997-01-01

Discusses issues related to electronic publishing. Topics include writing; reading; production, distribution, and commerce; copyright and ownership of intellectual property; archival storage; technical obsolescence; control of content; equality of access; and cultural changes. (Author/LRW)

Fusion Canada issue 20

International Nuclear Information System (INIS)

1993-03-01

Fusion Canada's publication of the National Fusion Program. Included in this issue is the CFFTP Industrial Impact Study, CCFM/TdeV Update:helium pumping, research funds, and deuterium in beryllium - high temperature behaviour. 3 figs

Fusion Canada issue 11

Energy Technology Data Exchange (ETDEWEB)

NONE

1990-06-01

A short bulletin from the National Fusion Program. Included in this issue is a report on operation at Tokamak de Varennes, CRITIC irradiations at AECL, Tritium systems at TFTR, physics contribution at ITER. 4 figs.

Fusion Canada issue 10

International Nuclear Information System (INIS)

1990-02-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Fusion Materials Research, ITER physics research, fusion performance record at JET, and design options for reactor building. 4 figs

Including Children Dependent on Ventilators in School.

Science.gov (United States)

Levine, Jack M.

1996-01-01

Guidelines for including ventilator-dependent children in school are offered, based on experience with six such students at a New York State school. Guidelines stress adherence to the medical management plan, the school-family partnership, roles of the social worker and psychologist, orientation, transportation, classroom issues, and steps toward…

PAPER ON MISCELLANEOUS ISSUES, INCLUDING WORKPLACE PRIVACY

OpenAIRE

Richards, G. W.

2014-01-01

EU directives give member states a certain period – say 2 or 3 years – to implement rules at national level. In fact the DPA 1998 replaces earlier UK legislation, the Data Protection Act 1984, so it does more than simply reproduce the directive. Other examples of subjects covered by directives are redundancy information/ consultation, equal treatment, insolvency protection, pregnancy protection, European and domestic works councils and agency work

Ethical issues in neurogenetics.

Science.gov (United States)

Uhlmann, Wendy R; Roberts, J Scott

2018-01-01

Many neurogenetic conditions are inherited and therefore diagnosis of a patient will have implications for the patient's relatives and can raise ethical issues. Predictive genetic testing offers asymptomatic relatives the opportunity to determine their risk status for a neurogenetic condition, and professional guidelines emphasize patients' autonomy and informed, voluntary decision making. Beneficence and nonmaleficence both need to be considered when making decisions about disclosure and nondisclosure of genetic information and test results. There can be disclosure concerns and challenges in determining whose autonomy to prioritize when a patient makes a genetic testing decision that can reveal the genetic status of a relative (e.g., testing an adult child when the at-risk parent has not been tested). Ethical issues are prominent when genetic testing for neurogenetic conditions is requested prenatally, on minors, adoptees, adult children at 25% risk, and for individuals with psychiatric issues or cognitive impairment. Neurogenetic conditions can result in cognitive decline which can affect decisional capacity and lead to ethical challenges with decision making, informed consent, and determining the patient's ability to comprehend test results. The ethical implications of genetic testing and emerging issues, including direct-to-consumer genetic testing, disclosure of secondary findings from genomic sequencing, and use of apolipoprotein E testing in clinical and research settings, are also discussed. Resources for information about genetic testing practice guidelines, insurance laws, and directories of genetics clinics are included. Copyright © 2018 Elsevier B.V. All rights reserved.

Matrix Diffusion for Performance Assessment - Experimental Evidence, Modelling Assumptions and Open Issues

Energy Technology Data Exchange (ETDEWEB)

Jakob, A

2004-07-01

In this report a comprehensive overview on the matrix diffusion of solutes in fractured crystalline rocks is presented. Some examples from observations in crystalline bedrock are used to illustrate that matrix diffusion indeed acts on various length scales. Fickian diffusion is discussed in detail followed by some considerations on rock porosity. Due to the fact that the dual-porosity medium model is a very common and versatile method for describing solute transport in fractured porous media, the transport equations and the fundamental assumptions, approximations and simplifications are discussed in detail. There is a variety of geometrical aspects, processes and events which could influence matrix diffusion. The most important of these, such as, e.g., the effect of the flow-wetted fracture surface, channelling and the limited extent of the porous rock for matrix diffusion etc., are addressed. In a further section open issues and unresolved problems related to matrix diffusion are mentioned. Since matrix diffusion is one of the key retarding processes in geosphere transport of dissolved radionuclide species, matrix diffusion was consequently taken into account in past performance assessments of radioactive waste repositories in crystalline host rocks. Some issues regarding matrix diffusion are site-specific while others are independent of the specific situation of a planned repository for radioactive wastes. Eight different performance assessments from Finland, Sweden and Switzerland were considered with the aim of finding out how matrix diffusion was addressed, and whether a consistent picture emerges regarding the varying methodology of the different radioactive waste organisations. In the final section of the report some conclusions are drawn and an outlook is given. An extensive bibliography provides the reader with the key papers and reports related to matrix diffusion. (author)

Issues Raised in Relation to Radioactive Waste Management

International Nuclear Information System (INIS)

Atherton, Elizabeth

2003-01-01

Nirex has undertaken various consultations with different stakeholders to identify their issues and concerns about radioactive waste management in general and specific aspects of Nirex's work. This paper will outline what dialogue techniques Nirex has undertaken and the issues and concerns that people have raised during the events. It will outline some of the work that Nirex is undertaking to address stakeholders' issues and concerns. Nirex has used a variety of dialogue techniques co-ordinated under the Nirex Involvement Programme to engage with stakeholders about the work we undertake. We are now trying to address the issues, concerns, scenarios and questions raised in our work programme. Key lessons that we have learned in undertaking the dialogues include: The importance of appropriate facilitation and organisation of meetings; The need for a clear purpose for meetings; Being flexible to the needs of the attendees and the issues they raise; Providing feedback to those who participate and following up issues. Through engaging with the public Nirex has learned that: Radioactive waste is not an everyday concern for people; The public can, will and want to engage with the issue of radioactive waste management. This includes engaging with the ethical debate. To facilitate this Nirex and others need to: Provide information in a neutral form outlining the pros and cons and including various people's opinions; Use proactive techniques to allow access and space for people to discuss the issues; Demonstrate how people's opinions have been taken into account. People understand the issues very differently to the way institutions understand them. There is a need for institutions to learn to understand public concerns and the ways in which the public understand issues, as well as for the public to understand the institutional positions better. We are using these insights to develop our future work in this area

Methodological Issues and Practices in Qualitative Research.

Science.gov (United States)

Bradley, Jana

1993-01-01

Discusses methodological issues concerning qualitative research and describes research practices that qualitative researchers use to address these methodological issues. Topics discussed include the researcher as interpreter, the emergent nature of qualitative research, understanding the experience of others, trustworthiness in qualitative…

Not all IGHV3-21 chronic lymphocytic leukemias are equal

DEFF Research Database (Denmark)

Baliakas, Panagiotis; Agathangelidis, Andreas; Hadzidimitriou, Anastasia

2015-01-01

An unresolved issue in chronic lymphocytic leukemia (CLL) is whether IGHV3-21 gene usage, in general, or the expression of stereotyped B-cell receptor immunoglobulin defining subset #2 (IGHV3-21/IGLV3-21), in particular, determines outcome for IGHV3-21-utilizing cases. We reappraised this issue...

Fix my child: The importance of including siblings in clinical assessments.

Science.gov (United States)

Farnfield, Steve

2017-07-01

This study examined concordance in the attachment strategies of school-aged siblings with reference to environmental risk in terms of poverty and maltreatment. It also investigated the effect of child maltreatment and maternal mental illness on children's psychosocial functioning in terms of the Dynamic-Maturational Model of Attachment and Adaptation (DMM) including unresolved trauma and the DMM Depressed modifier. The attachment strategies of 30 sibling pairs, aged 5-14 years, were assessed using the School-age Assessment of Attachment (SAA). Unlike most previous studies, this study included siblings from large families of two to six children. The main finding was that as environmental risk increases, the diversity of sibling attachment strategies decreases with greater recourse to the DMM Type A3-6 and A/C strategies. Unlike previous studies, the highest level of concordance was found in sibling pairs with the opposite gender. Boys whose mothers had a history of mental illness were significantly more likely than girls to be assessed with the DMM-depression modifier. As danger increases, children in the same family experience more of the same childhood. Further research should focus on single case, intra-familial studies to build a systemic model of the shared environment. Research should also evaluate the effects of environmental risk compared with size of the sibling group on children's attachment strategies. The clinical implications point to the importance of assessing all children in the family using a model built around functional formulation rather than diagnosing the symptoms of a particular child.

Is the Current US Navy Pacific Basing Structure Adequate for the Twenty-First Century?

National Research Council Canada - National Science Library

Alinio, Domingo B

2006-01-01

.... Despite its unresolved issues with Taiwan, territorial disputes in the South and East China Seas, and its ambiguous reaction to North Korea, China continues with its significant naval modernization...

Fusion Canada issue 6

International Nuclear Information System (INIS)

1989-02-01

A short bulletin from the National Fusion Program. Included in this issue is a funding report for CFFTP, a technical update for Tokamak de Varennes and a network for university research by the National Fusion Program. 4 figs

A brief exegesis of End Triassic Extinction issues

Science.gov (United States)

Whiteside, J. H.; Grice, K.; Fox, C.; Kent, D. V.; Olsen, P. E.; Irmis, R. B.

2017-12-01

Recent reports of environmental proxy records through the end-Triassic extinction (ETE), in some cases coupled with high-resolution geochronologic data, provide new insights into cause and effect. For example, the emplacement of vast volumes of basalt in the Central Atlantic Magmatic Province (CAMP) are temporally associated with carbon isotopic excursions (CIEs), indications of widespread oceanic euxinia, distinct regional and perhaps very abrupt global sea level change, massive changes in atmospheric CO2, and the proliferation of "disaster" species, both on land and ocean. In the least, these indicate major disruptions in how the Earth works. However some striking and critical issues remain unresolved at a very basic level. Most important are the uncertainties in the stratigraphic relationships of marine extinctions to the various environmental proxy sections, particularly the GSSP for the base Hettangian in Austria, and the UK sections (notably St. Audrie's Bay). Here, the sequence of sporomorph and marine "invertebrate" turnover occurs in different order relative to the proxy record and lithostratigraphy. Thus the sequence of environmental events are, at present, of uncertain relationship to the extinction. Second, it is unclear what processes the various CIEs reflect in different environments; the canonical initial isotopic excursion in the UK, demonstrably correlatable over a huge area, was recorded in a lake in a restricted basin, unlike the isotopic data from surrounding marine strata. Could some CIEs in non-marine basins be diagenetic in nature, caused by the contact effects of overlying basalts? Finally, how does the clear and dramatic tropical non-marine record of the ETE, precisely located relative to the CAMP, relate to the marine record of the ETE, particularly at higher latitudes, where continental biotic turnover is not nearly as dramatic? Do these records correlate in a sufficiently tight temporal interval such that causation can be inferred? These

Measurements in Accounting: Issues and Choices Determinants ...

African Journals Online (AJOL)

This paper examines the common measurements in accounting, addressing the issues in general terms, including the circumstances and situations that determine each accounting measurement choice .To drive these issues, references were made to extant literature on common measurement bases and while each ...

Australian uranium - the environmental issues

International Nuclear Information System (INIS)

Saddler, H.

1980-01-01

The principal theme of this paper is the changing pattern of issues which have dominated the environmental debate over uranium mining in Australia. These issues include the safeguards policy, a domestic energy policy, nuclear waste, economic development, particular environmental problems of the Alligator Rivers region and the social impact of uranium mining on the Aborigines. The special administrative arrangements which the Government has established for environmental protection in the Alligator Rivers region are outlined

Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition

Directory of Open Access Journals (Sweden)

Satoshi Nori

2015-03-01

Full Text Available Previously, we described the safety and therapeutic potential of neurospheres (NSs derived from a human induced pluripotent stem cell (iPSC clone, 201B7, in a spinal cord injury (SCI mouse model. However, several safety issues concerning iPSC-based cell therapy remain unresolved. Here, we investigated another iPSC clone, 253G1, that we established by transducing OCT4, SOX2, and KLF4 into adult human dermal fibroblasts collected from the same donor who provided the 201B7 clone. The grafted 253G1-NSs survived, differentiated into three neural lineages, and promoted functional recovery accompanied by stimulated synapse formation 47 days after transplantation. However, long-term observation (for up to 103 days revealed deteriorated motor function accompanied by tumor formation. The tumors consisted of Nestin+ undifferentiated neural cells and exhibited activation of the OCT4 transgene. Transcriptome analysis revealed that a heightened mesenchymal transition may have contributed to the progression of tumors derived from grafted cells.

Preface to the April 2018 Issue including selected works from CIbSE 2017 and LACLO 2016

Directory of Open Access Journals (Sweden)

Héctor Cancela

2018-04-01

Full Text Available This issue of the CLEIej consists of three main parts: i a review paper on the state of the art of how contextual information extracted from a user task can help to improve searches for contents relevant to this task; ii extended and revised versions of Selected Papers (which correspond to the second and third best paper from each track presented at the XX Ibero-American Conference on Software Engineering (CIbSE 2017, which took place in Buenos Aires, Argentina, in May 2017; and, iii extended and revised versions of selected papers from LACLO 2016, the XI Latin American Conference on Learning Objects and Technology, which took place in San José, Costa Rica, in October 2016.

Inclusion of ethical issues in dementia guidelines: a thematic text analysis.

Science.gov (United States)

Knüppel, Hannes; Mertz, Marcel; Schmidhuber, Martina; Neitzke, Gerald; Strech, Daniel

2013-08-01

Clinical practice guidelines (CPGs) aim to improve professionalism in health care. However, current CPG development manuals fail to address how to include ethical issues in a systematic and transparent manner. The objective of this study was to assess the representation of ethical issues in general CPGs on dementia care. To identify national CPGs on dementia care, five databases of guidelines were searched and national psychiatric associations were contacted in August 2011 and in June 2013. A framework for the assessment of the identified CPGs' ethical content was developed on the basis of a prior systematic review of ethical issues in dementia care. Thematic text analysis and a 4-point rating score were employed to assess how ethical issues were addressed in the identified CPGs. Twelve national CPGs were included. Thirty-one ethical issues in dementia care were identified by the prior systematic review. The proportion of these 31 ethical issues that were explicitly addressed by each CPG ranged from 22% to 77%, with a median of 49.5%. National guidelines differed substantially with respect to (a) which ethical issues were represented, (b) whether ethical recommendations were included, (c) whether justifications or citations were provided to support recommendations, and (d) to what extent the ethical issues were explained. Ethical issues were inconsistently addressed in national dementia guidelines, with some guidelines including most and some including few ethical issues. Guidelines should address ethical issues and how to deal with them to help the medical profession understand how to approach care of patients with dementia, and for patients, their relatives, and the general public, all of whom might seek information and advice in national guidelines. There is a need for further research to specify how detailed ethical issues and their respective recommendations can and should be addressed in dementia guidelines. Please see later in the article for the Editors

MCNP/X TRANSPORT IN THE TABULAR REGIME

Energy Technology Data Exchange (ETDEWEB)

HUGHES, H. GRADY [Los Alamos National Laboratory

2007-01-08

The authors review the transport capabilities of the MCNP and MCNPX Monte Carlo codes in the energy regimes in which tabular transport data are available. Giving special attention to neutron tables, they emphasize the measures taken to improve the treatment of a variety of difficult aspects of the transport problem, including unresolved resonances, thermal issues, and the availability of suitable cross sections sets. They also briefly touch on the current situation in regard to photon, electron, and proton transport tables.

Discussion: How different can perspectives on L2 development be?

NARCIS (Netherlands)

Hulstijn, J.H.

2015-01-01

In this article I discuss the contributions to this special issue of Language Learning on orders and sequences in second language (L2) development. Using a list of questions, I attempt to characterize what I see as the strengths, limitations, and unresolved issues in the approaches to L2 development

Dialogue on Solutions to the Palestinian Refugee Problem | CRDI ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Palestinian refugee issue remains a key component of any just and lasting resolution to the Palestinian Israeli conflict. How the subject is addressed will shape the future of the Middle East; unresolved refugee issues will prevent a durable peace between Israelis and Palestinians. This project will enhance the capacity ...

The Alsos library for nuclear issues

International Nuclear Information System (INIS)

Settle, F.A.; Whaley, T.; Blackmer, E.

2005-01-01

Full text: This presentation will describe the content and features of the Alsos Digital Library for Nuclear Issues (http://alsos.wlu.edu). The library, funded by the U.S. National Science Foundation, provides a broad, balanced collection of indexed, annotated references for the study of nuclear issues ranging from nuclear reactors to Japanese poetry. All annotations have been reviewed by members of the library's prestigious National Advisory Board. The searchable collection includes books, articles, films, CD-ROMs, and websites. It currently contains approximately 1600 references and receives over 15000 visits per month. The mission of the library is to make the history and current status of nuclear issues more accessible and comprehensible to the general public as well as to students, educators, and other professionals in the many fields influenced by the forces of the nuclear age. References may be accessed by conventional keyword, creator, and title searches or by browsing topics under one of five categories; issues, warfare, science, people, and places. Of particular interest to conference participants are topics in the issues category that include nuclear power, terrorism, and nuclear waste. The library can also provide bibliographies for specific topics which can be embedded as hyperlinks on other websites which address of nuclear issues. Finally the Alsos Library is the bibliographical component of Nuclear Pathways (nuclearpathways.org), a composite site which is attempting to integrate websites dedicated to nuclear issues. The initial partner sites are: Atomic Archive (http://atomicarchive.com), Nuclear Chemistry in the Community (http://www.chemcases.com/2003version/nuclear/index2.htm), and Nuclear Files (http://nuclearfiles.org). (author)

Electric Power Monthly, August 1990. [Glossary included

Energy Technology Data Exchange (ETDEWEB)

1990-11-29

The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national, Census division, and State level. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data includes generation by energy source (coal, oil, gas, hydroelectric, and nuclear); generation by region; consumption of fossil fuels for power generation; sales of electric power, cost data; and unusual occurrences. A glossary is included.

Bioremediation: is it the solution to reclamation of heavy oil contaminated soils in the Canadian climate?

International Nuclear Information System (INIS)

Goodman, R.; Nicholson, P.; Varga, M.; Boadi, D.; Yang, A.

1997-01-01

The issue of bioremediation of heavy oil contaminated soils in cold climates was discussed. No model of the bioremediation system for cold climates exists. Environmental groups use three environmental concepts as the basis to evaluate petroleum activities: (1) cradle to grave responsibility, (2) the precautionary principle, and (3) sustainable development. The reclamation of an abandoned petroleum production facility must meet stringent standards. Most sites are contaminated with weathered hydrocarbons, brine and other chemicals that have been used at the location. Bioremediation, either in-situ or ex-situ, is one of the lowest cost remediation techniques available and has been used extensively by the downstream petroleum industry in warm climates. However, there are many unresolved issues with the use of bioremediation in cold climates, for heavy or weathered crude oil products and in areas of clay or other low permeability. Some of these unresolved issues are highlighted

URR [Unresolved Resonance Region] computer code: A code to calculate resonance neutron cross-section probability tables, Bondarenko self-shielding factors, and self-indication ratios for fissile and fertile nuclides

International Nuclear Information System (INIS)

Leal, L.C.; de Saussure, G.; Perez, R.B.

1989-01-01

The URR computer code has been developed to calculate cross-section probability tables, Bondarenko self-shielding factors, and self- indication ratios for fertile and fissile isotopes in the unresolved resonance region. Monte Carlo methods are utilized to select appropriate resonance parameters and to compute the cross sections at the desired reference energy. The neutron cross sections are calculated by the single-level Breit-Wigner formalism with s-, p-, and d-wave contributions. The cross-section probability tables are constructed by sampling the Doppler broadened cross-section. The various shelf-shielded factors are computed numerically as Lebesgue integrals over the cross-section probability tables. 6 refs

Fusion Canada issue 12

International Nuclear Information System (INIS)

1990-10-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Darlington's Tritium Removal Facility, work at universities on Deuterium Diffusivity in Beryllium, Fusion Studies, confinement research and the operation of divertors at Tokamak de Varennes. 5 figs

ADA members weigh in on critical issues.

Science.gov (United States)

Burgess, Karen; Ruesch, Jon D; Mikkelsen, Matthew C; Wagner, Karen Schaid

2003-01-01

Science, new technology, patient care, dental reimbursement and government regulations all affect today's dental practitioners. To find out more about how such challenges may affect current private practitioners, the American Dental Association conducted the 2000 Membership Needs and Opinions Survey. A questionnaire was sent to 6,310 ADA members in January 2000 with follow-up mailings in February, March and April 2000. Data collection was completed in July 2000. The survey included questions on critical professional issues, and on perceptions of the ADA and ADA priorities. A total of 3,558 completed surveys were received for an adjusted response rate of 59.5 percent. Members rated the identified issues' level of importance to them. The top three issues included "maintaining my ability to recommend the treatment option I feel is most appropriate for my patients," "receiving fair reimbursement for the dental services I provide," and "protecting myself, my staff and my patients from communicable diseases." New dentists found other items to be more significant to them compared with members overall. Although ADA members as a whole had similar views on critical issues facing dentistry and ADA priorities, there were significant differences regarding some issues. New dentists were far more concerned about securing funds for their practice and paying off debt than were all ADA members. Minority dentists expressed greater levels of concern about certain issues than did all ADA members. When planning and implementing ADA activities, the Association should continue to take into account members' relative rankings of professional issues and note issues of special interest to selected membership subgroups.

Strategic issues for the oil majors - 1992

Energy Technology Data Exchange (ETDEWEB)

Oppenheimer, P M [Oxford Univ. (United Kingdom)

1992-01-01

Strategic issues facing major oil producers in the 1990s are very diffuse - in contrast with both the 1970s (when strategy meant the response to high oil prices) and the 1980s (when it meant anticipating and exploiting a drop in prices). Mainly upstream issues include the future of price management by OPEC or a successor, the speed of development of new markets for natural gas in power generation and the role of Russia in world energy markets. Other issues include the impact of environmental regulations and taxes on the product mix and on marketing. Human-resource management will continue to face the task of reconciling career opportunities with static or declining manpower requirements; and corporate cash mountains may periodically recur. (Author).

Strategic issues for the oil majors - 1992

International Nuclear Information System (INIS)

Oppenheimer, P.M.

1992-01-01

Strategic issues facing major oil producers in the 1990s are very diffuse - in contrast with both the 1970s (when strategy meant the response to high oil prices) and the 1980s (when it meant anticipating and exploiting a drop in prices). Mainly upstream issues include the future of price management by OPEC or a successor, the speed of development of new markets for natural gas in power generation and the role of Russia in world energy markets. Other issues include the impact of environmental regulations and taxes on the product mix and on marketing. Human-resource management will continue to face the task of reconciling career opportunities with static or declining manpower requirements; and corporate cash mountains may periodically recur. (Author)

Fusion Canada issue 7

International Nuclear Information System (INIS)

1989-05-01

A short bulletin from the National Fusion Program. Included in this issue are CFFTP highlights on the Karlsruhe Isotope Separation System, a report on ITER tritium process systems, an experimental update on Tokamak de Varennes and Canada-U.S. bilateral technical collaboration topics. 2 figs

Fusion Canada issue 7

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-05-01

A short bulletin from the National Fusion Program. Included in this issue are CFFTP highlights on the Karlsruhe Isotope Separation System, a report on ITER tritium process systems, an experimental update on Tokamak de Varennes and Canada-U.S. bilateral technical collaboration topics. 2 figs.

Fusion Canada issue 12

Energy Technology Data Exchange (ETDEWEB)

NONE

1990-10-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Darlington`s Tritium Removal Facility, work at universities on Deuterium Diffusivity in Beryllium, Fusion Studies, confinement research and the operation of divertors at Tokamak de Varennes. 5 figs.

Intermittent fasting and cardiovascular disease: current evidence and unresolved questions.

Science.gov (United States)

Tinsley, Grant M; Horne, Benjamin D

2018-01-01

Intermittent fasting has produced a variety of beneficial health effects in animal models, although high-quality research in humans has been limited. This special report examines current evidences for intermittent fasting in humans, discusses issues that require further examination, and recommends new research that can improve the knowledge base in this emerging research area. While potentially useful for health improvement, intermittent fasting requires further study prior to widespread implementation for health purposes. Randomized, longer-term studies are needed to determine whether using intermittent fasting as a lifestyle rather than a diet is feasible and beneficial for the health of some members of the human population.

Natural gas 1998: Issues and trends

International Nuclear Information System (INIS)

1999-06-01

Natural Gas 1998: Issues and Trends provides a summary of the latest data and information relating to the US natural gas industry, including prices, production, transmission, consumption, and the financial and environmental aspects of the industry. The report consists of seven chapters and five appendices. Chapter 1 presents a summary of various data trends and key issues in today's natural gas industry and examines some of the emerging trends. Chapters 2 through 7 focus on specific areas or segments of the industry, highlighting some of the issues associated with the impact of natural gas operations on the environment. 57 figs., 18 tabs

Natural gas 1998: Issues and trends

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-06-01

Natural Gas 1998: Issues and Trends provides a summary of the latest data and information relating to the US natural gas industry, including prices, production, transmission, consumption, and the financial and environmental aspects of the industry. The report consists of seven chapters and five appendices. Chapter 1 presents a summary of various data trends and key issues in today`s natural gas industry and examines some of the emerging trends. Chapters 2 through 7 focus on specific areas or segments of the industry, highlighting some of the issues associated with the impact of natural gas operations on the environment. 57 figs., 18 tabs.

The nuclear controversy-what are the issues

International Nuclear Information System (INIS)

Wyatt, A.

1976-01-01

The various issues raised by anti-nuclear groups are outlined and rebutted. Issues are grouped under four headingss - Economic; Technical; Social/Ethical/Moral; Political. Issues debated under economic aspects include conservation, unemployment resulting from energy use, use of alternative enrgy sources, high capital cost of nuclear power, high energy consumption in construction of plants, performance unreliability, depletion of uranium and excessive cost of decommissioning. Technically related issues, reactor safety, possibility of nuclear power plant explosion, waste managment, toxicity of plutonium, emission of radioactive material, thermal pollution and environmental effect of heavy water production are also discussed. Social/ethical/moral issues rebutted include radiation effects on health and genetic effects, deaths among uranium miners, morality of long-term waste storage, lack of faith in technical solutions and technical people, opposition to current life style, secrecy of information, nuclear proliferation and unsuitability of nuclear technology to the needs of developing countries. Political issues discussed are sabotage/terrorism possibilites, police state tactics in protection of nuclear facilities, misuse of technolgy by society, high energy society is capitalist and low energy society is Marxist, centralization of power, need for a great nuclear debate and the question of who pays for safety. Scientists and technical people are called upon to debate in their areas of specialty and are cautioned to be aware of tactics involved in meeting challengers head-on. (J.T.A.)

Smart-Glasses: Exposing and Elucidating the Ethical Issues.

Science.gov (United States)

Hofmann, Bjørn; Haustein, Dušan; Landeweerd, Laurens

2017-06-01

The objective of this study is to provide an overview over the ethical issues relevant to the assessment, implementation, and use of smart-glasses. The purpose of the overview is to facilitate deliberation, decision making, and the formation of knowledge and norms for this emerging technology. An axiological question-based method for human cognitive enhancement including an extensive literature search on smart-glasses is used to identify relevant ethical issues. The search is supplemented with relevant ethical issues identified in the literature on human cognitive enhancement (in general) and in the study of the technical aspects of smart-glasses. Identified papers were subject to traditional content analysis: 739 references were identified of which 247 were regarded as relevant for full text examinations, and 155 were included in the study. A wide variety of ethical issues with smart-glasses have been identified, such as issues related to privacy, safety, justice, change in human agency, accountability, responsibility, social interaction, power and ideology. Smart-glasses are envisioned to change individual human identity and behavior as well as social interaction. Taking these issues into account appears to be relevant when developing, deliberating, deciding on, implementing, and using smart-glasses.

Fusion Canada issue 8

International Nuclear Information System (INIS)

1989-08-01

A short bulletin from the National Fusion Program. Included in this issue are Canada-ITER contributions, NET Fuel Processing Loop, Bilateral Meeting for Canada-Europe, report from Tokamak de Varennes and a report from the University of Toronto on materials research for Fusion Reactors. 3 figs

Fusion Canada issue 8

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-08-01

A short bulletin from the National Fusion Program. Included in this issue are Canada-ITER contributions, NET Fuel Processing Loop, Bilateral Meeting for Canada-Europe, report from Tokamak de Varennes and a report from the University of Toronto on materials research for Fusion Reactors. 3 figs.

Issues and trends in radioactive waste management in Turkey

International Nuclear Information System (INIS)

Osmanlioglu, A.E.

2002-01-01

This paper focuses on issues associated with the waste management aspects of Turkey. Predisposal management of radioactive wastes covers a broad range of activities. This also includes waste identification, characterization and conditioning. Experience gained over years shows that current predisposal waste management practices are well advanced. The paper concludes these activities based on experience gained by CWPSF (CNAEM Waste Processing and Storage Facility) and includes issues and trends in radioactive waste management. In addition general information is presented on ongoing national projects and IAEA research projects on various issues of waste management. (author)

Implementation Issues for Departure Planning Systems

Science.gov (United States)

Hansman, R. John; Feron, Eric; Clarke, John-Paul; Odoni, Amedeo

1999-01-01

The objective of the proposed effort is to investigate issues associated with the design and implementation of decision aiding tools to assist in improving the departure process at congested airports. This effort follows a preliminary investigation of potential Departure Planning approaches and strategies, which identified potential benefits in departure efficiency, and also in reducing the environmental impact of aircraft in the departure queue. The preliminary study bas based, in large part, on observations and analysis of departure processes at Boston, Logan airport. The objective of this follow-on effort is to address key implementation issues and to expand the observational base to include airports with different constraints and traffic demand. Specifically, the objectives of this research are to: (1) Expand the observational base to include airports with different underlying operational dynamics. (2) Develop prototype decision aiding algorithms/approaches and assess potential benefits. and (3) Investigate Human Machine Integration (HMI) issues associated with decision aids in tower environments.

Ethical issues in publishing in predatory journals.

Science.gov (United States)

Ferris, Lorraine E; Winker, Margaret A

2017-06-15

Predatory journals, or journals that charge an article processing charge (APC) to authors, yet do not have the hallmarks of legitimate scholarly journals such as peer review and editing, Editorial Boards, editorial offices, and other editorial standards, pose a number of new ethical issues in journal publishing. This paper discusses ethical issues around predatory journals and publishing in them. These issues include misrepresentation; lack of editorial and publishing standards and practices; academic deception; research and funding wasted; lack of archived content; and undermining confidence in research literature. It is important that the scholarly community, including authors, institutions, editors, and publishers, support the legitimate scholarly research enterprise, and avoid supporting predatory journals by not publishing in them, serving as their editors or on the Editorial Boards, or permitting faculty to knowingly publish in them without consequences.

Animal Experimentation: Issues for the 1980s.

Science.gov (United States)

Zola, Judith C.; And Others

1984-01-01

Examines the extent to which issues related to animal experimentation are in conflict and proposes choices that might least comprise them. These issues include animal well-being, human well-being, self-interest of science, scientific validity and responsibility, progress in biomedical and behavioral science, and the future quality of medical care.…

Beyond the standard model

International Nuclear Information System (INIS)

Gaillard, M.K.

1990-04-01

The unresolved issues of the standard model are reviewed, with emphasis on the gauge hierarchy problem. A possible mechanism for generating a hierarchy in the context of superstring theory is described. 24 refs

Strategy and issues for the LHC upgrades and fair, including longer-term prospects

CERN Document Server

Zimmermann, F

2013-01-01

This report discusses the time line, goals and key ingredients for the next ten years of LHC operation, including injector upgrade, for the following High Luminosity LHC (HL-LHC), and for the FAIR project. Results from pertinent EuCARD-WP4 workshops on optics, space charge, crab cavities, crystal collimation, and electron cloud are summarized in this context. A Large Hadron electron Collider, LHeC, would be an additional upgrade, further expanding the physics scope of the LHC, to eventually include both ep and γγ Higgs factories (LHeC-HF and SAPPHiRE). Results from relevant topical WP4 workshops are highlighted. The development of magnet and cable technology based on Nb$_{3}$Sn, and HTS, for the HL-LHC prepares the ground for a future higher-energy hadron collider, either in the LHC tunnel, “HELHC” (33 TeV c.m.), or in a new 80- or 100-km tunnel, “VHE-LHC” (100 TeV c.m.). A large new tunnel could also host an ultimate highest-precision e+e- Higgs factory collider, “TLEP,” exhibiting many synergi...

Environmental issues: I - Energy utilization

International Nuclear Information System (INIS)

Dincer, I.

2001-01-01

In this article, energy utilization and its major environmental impacts are discussed from the standpoint of sustainable development, including anticipated patterns of future energy use and consequent environmental issues and policies. Overall, the paper also examines several issues related to energy utilization, environment, sustainable development from both current and future perspectives, and energy use and its environmental impacts in the transportation sector. Finally, the conclusions and recommendations are presented in the form to be beneficial to energy scientists, engineers and energy policy makers. (author)

UK energy issues 1987-1992

Energy Technology Data Exchange (ETDEWEB)

Stern, P J

1987-01-01

This paper describes and analyses the energy issues and options which the British Government will either choose, or be required, to address over the next five years. After considering the domestic and international environment, the paper looks at the future for: electricity generation, and the coal industry in the light of the decision to privatise the Electricity Supply Industry; the oil and gas sector; research and development; demand and conservation including fuel poverty; energy pricing; international energy issues; and attitudes to energy policy making. 80 refs.

SAT project introduction: management issues

International Nuclear Information System (INIS)

Kazennov, A.Yu.

1998-01-01

Management issues of introducing SAT Project include main objectives and expectations; SAT goal and management; major phases of SAT implementation; project quality assurance; SAT based training system and procedures; role of the project team qualifications

Management issues in automated audit analysis

Energy Technology Data Exchange (ETDEWEB)

Jackson, K.A.; Hochberg, J.G.; Wilhelmy, S.K.; McClary, J.F.; Christoph, G.G.

1994-03-01

This paper discusses management issues associated with the design and implementation of an automated audit analysis system that we use to detect security events. It gives the viewpoint of a team directly responsible for developing and managing such a system. We use Los Alamos National Laboratory`s Network Anomaly Detection and Intrusion Reporter (NADIR) as a case in point. We examine issues encountered at Los Alamos, detail our solutions to them, and where appropriate suggest general solutions. After providing an introduction to NADIR, we explore four general management issues: cost-benefit questions, privacy considerations, legal issues, and system integrity. Our experiences are of general interest both to security professionals and to anyone who may wish to implement a similar system. While NADIR investigates security events, the methods used and the management issues are potentially applicable to a broad range of complex systems. These include those used to audit credit card transactions, medical care payments, and procurement systems.

Environmental licensing issues for cogeneration plants

International Nuclear Information System (INIS)

Lipka, G.S.; Bibbo, R.V.

1990-01-01

The siting and licensing of cogeneration and independent power production (IPP) facilities is a complex process involving a number of interrelated engineering, economic, and environmental impact considerations. Important considerations for the siting and licensing of such facilities include air quality control and air quality impacts, water supply and wastewater disposal, and applicable noise criteria and noise impact considerations. Air quality control and air quality impact considerations for power generation facilities are commonly reviewed in the public forum, and most project developers are generally aware of the key air quality licensing issues. These issues include Best Available Control Technology (BACT) demonstration requirements, and air quality modeling requirements. BACT is a case-by-case determination, which causes uncertainty, in that developers have difficulty in projecting the cost of required control systems. Continuing developments in control technology may cause this problem to continue in the 1990's. Air quality modeling can be a problem in hilly terrain or within or near an urban environment, which could delay or preclude permitting of a new cogeneration or IPP facility in such locations. This paper discusses several environmental issues which are less frequently addressed than air quality issues, namely water/wastewater and noise. The design features of typical cogeneration and IPP facilities that affect water supply requirements, wastewater volumes, and noise emissions are discussed. Then, the site selection and impact review process are examined to identify typical constraints and trade-offs that can develop relative to water, wastewater, and noise issues. Trends in permit review requirements for water, wastewater, and noise are examined. Finally, innovative approaches that can be used to resolve potential development constraints for water, wastewater, and noise issues are discussed

Calcium in the prevention of postmenopausal osteoporosis: EMAS clinical guide.

Science.gov (United States)

Cano, Antonio; Chedraui, Peter; Goulis, Dimitrios G; Lopes, Patrice; Mishra, Gita; Mueck, Alfred; Senturk, Levent M; Simoncini, Tommaso; Stevenson, John C; Stute, Petra; Tuomikoski, Pauliina; Rees, Margaret; Lambrinoudaki, Irene

2018-01-01

Postmenopausal osteoporosis is a highly prevalent disease. Prevention through lifestyle measures includes an adequate calcium intake. Despite the guidance provided by scientific societies and governmental bodies worldwide, many issues remain unresolved. To provide evidence regarding the impact of calcium intake on the prevention of postmenopausal osteoporosis and critically appraise current guidelines. Literature review and consensus of expert opinion. The recommended daily intake of calcium varies between 700 and 1200mg of elemental calcium, depending on the endorsing source. Although calcium can be derived either from the diet or supplements, the former source is preferred. Intake below the recommended amount may increase fragility fracture risk; however, there is no consistent evidence that calcium supplementation at, or above, recommended levels reduces risk. The addition of vitamin D may minimally reduce fractures, mainly among institutionalised people. Excessive intake of calcium, defined as higher than 2000mg/day, can be potentially harmful. Some studies demonstrated harm even at lower dosages. An increased risk for cardiovascular events, urolithiasis and even fractures has been found in association with excessive calcium intake, but this issue remains unresolved. In conclusion, an adequate intake of calcium is recommended for general bone health. Excessive calcium intake seems of no benefit, and could possibly be harmful. Copyright © 2017 Elsevier B.V. All rights reserved.

China-U.S. Trade Issues

National Research Council Canada - National Science Library

Morrison, Wayne M

2005-01-01

.... With a huge population and a rapidly expanding economy, China is becoming a large market for U.S. exporters. Yet, U.S.-China commercial ties have been strained by a number of issues, including a surging...

Professional Issues In Software Engineering

CERN Document Server

Bott, Frank; Eaton, Jack; Rowland, Diane

2000-01-01

An comprehensive text covering all the issues that software engineers now have to take into account apart from the technical side of things. Includes information on the legal, professional and commercial context in which they work.

Physics issues in mirror and tandem mirror systems

International Nuclear Information System (INIS)

Post, R.F.

1984-01-01

Over the years the study of the confinement of high temperature plasma in magnetic mirror systems has presented researchers with many unusual physics problems. Many of these issues are by now understood theoretically and documented experimentally. With the advent of the tandem mirror idea, some new issues have emerged and are now under intensive study. These include: (1) the generation and control of ambipolar confining potentials and their effect on axial confinement and, (2) the combined influence of nonaxisymmetric magnetic fields (used to ensure MHD stability) and electric magnetic particle drifts on radial transport. Physics considerations associated with these two categories of issues will be reviewed, including concepts for the control of radial transport, under study or proposed

PFP issues/assumptions development and management planning guide

International Nuclear Information System (INIS)

SINCLAIR, J.C.

1999-01-01

The PFP Issues/Assumptions Development and Management Planning Guide presents the strategy and process used for the identification, allocation, and maintenance of an Issues/Assumptions Management List for the Plutonium Finishing Plant (PFP) integrated project baseline. Revisions to this document will include, as attachments, the most recent version of the Issues/Assumptions Management List, both open and current issues/assumptions (Appendix A), and closed or historical issues/assumptions (Appendix B). This document is intended be a Project-owned management tool. As such, this document will periodically require revisions resulting from improvements of the information, processes, and techniques as now described. Revisions that suggest improved processes will only require PFP management approval

Liquid lithium applications for solving challenging fusion reactor issues and NSTX-U contributions

Energy Technology Data Exchange (ETDEWEB)

Ono, M., E-mail: mono@pppl.gov [Princeton Plasma Physics Laboratory, PO Box 451, Princeton, NJ 08543 (United States); Jaworski, M.A.; Kaita, R. [Princeton Plasma Physics Laboratory, PO Box 451, Princeton, NJ 08543 (United States); Hirooka, Y. [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Gray, T.K. [Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, TN 37831 (United States)

2017-04-15

Steady-state fusion reactor operation presents major divertor technology challenges, including high divertor heat flux both steady-state and transients. In addition, there are unresolved issues of long term dust accumulation and associated tritium inventory and safety concerns (Federici et al., 2001) . It has been suggested that radiative liquid lithium divertor concepts with a modest lithium-loop could provide a possible solution for these outstanding fusion reactor technology issues, while potentially improving reactor plasma performance (Ono et al., 2013, 2014) . The application of lithium (Li) in NSTX resulted in improved H-mode confinement, H-mode power threshold reduction, and reduction in the divertor peak heat flux while maintaining essentially Li-free core plasma operation even during H-modes. These promising results in NSTX and related modeling calculations motivated the radiative liquid lithium (LL) divertor (RLLD) concept (Ono et al., 2013) and its variant, the active liquid lithium divertor concept (ARLLD) (Ono et al., 2014) , taking advantage of the enhanced non-coronal Li radiation in relatively poorly confined divertor plasmas. It was estimated that only a few moles/s of lithium injection would be needed to significantly reduce the divertor heat flux in a tokamak fusion power plant. By operating at lower temperatures ≤450 °C than the first wall ∼600–700 °C, the LL-covered divertor chamber wall surfaces can serve as an effective particle pump, as impurities generally migrate toward lower temperature LL divertor surfaces. To maintain the LL purity, a closed LL loop system with a modest circulating capacity of ∼1 l/s (l/s) is envisioned to sustain the steady-state operation of a 1 GW-electric class fusion power plant. By running the Li loop continuously, it can carry the dust particles and impurities generated in the vacuum vessel to outside where the dust/impurities are removed by relatively simple filter and cold/hot trap systems. Using a

Deriving the true mass of an unresolved Brown Dwarf companion to an M-Dwarf with AO aided astrometry*

Directory of Open Access Journals (Sweden)

Kürster M.

2011-07-01

Full Text Available From radial velocity (RV detections alone one does not get all orbital parameters needed to derive the true mass of a non-transiting, unresolved substellar companion to a star. Additional astrometric measurements are needed to calculate the inclination and the longitude of the ascending node. Until today only few true substellar companion masses have been determined by this method with the HST fine guidance sensor [1, 2]. We aim to derive the true mass of a brown dwarf candidate companion to an early M 2.5V dwarf with groundbased high-resolution astrometry aided by adaptive optics. We found this unique brown dwarf desert object, whose distance to the host star is only 0.42 AU, in our UVES precision RV survey of M dwarfs, inferring a minimum companion mass of 27 Jupiter masses [3]. Combining the data with HIPPARCOS astrometry, we found a probability of only 2.9% that the companion is stellar. We therefore observed the host star together with a reference star within a monitoring program with VLT/NACO to derive the true mass of the companion and establish its nature (brown dwarf vs. star. Simultaneous observations of a reference field in a globular cluster are performed to determine the stability of the adaptive optics (AO plus detector system and check its suitability for such high-precision astrometric measurements over several epochs which are needed to find and analyse extrasolar planet systems.

Personal Health, Person-centred Health and Personalised Medicine - Concepts, Consumers, Confusion and Challenges in the Informatics World.

Science.gov (United States)

Rigby, M

2012-01-01

To define and assess 'Consumer Health Informatics' and related emergent issues in an era of new media and of personalisation of care, and from this to define what actions need to be taken to optimise benefits and address risks. Definition of key concepts; review of health personalisation, emergent health information and communication technologies and knowledge sources available to citizens and social media; and identification of unresolved issues threatening optimal use of each. A structured review supported by citations and examples. Several new aspects of consumer health informatics are emerging, including new knowledge sources, feedback on treatments and care providers, on-line videos, and a new generation of patient experience sites including those which are for profit and seek to influence treatment paradigms. Not just the information usage, but also the potential social challenges and malicious abuses, are global issues, and also transcend the traditional health community and thus should be addressed in partnership with other global agencies.

Reproductive issues in anorexia nervosa

Science.gov (United States)

Hoffman, Elizabeth R; Zerwas, Stephanie C; Bulik, Cynthia M

2011-01-01

Despite a high prevalence of menstrual irregularities, women with anorexia nervosa are becoming pregnant. The physical and psychological demands of pregnancy and motherhood can represent an immense challenge for women already struggling with the medical and psychological stress of an eating disorder. This article summarizes key issues related to reproduction in women with anorexia nervosa, highlighting the importance of preconception counseling, adequate gestational weight gain, and sufficient pre- and post-natal nutrition. Postpartum issues including eating disorder symptom relapse, weight loss, breastfeeding, and risk of perinatal depression and anxiety are also discussed. PMID:22003362

SKB annual report 1991. Including summaries of technical reports issued during 1991

International Nuclear Information System (INIS)

1992-05-01

This is the annual report on the activities of the Swedish Nuclear Fuel and Waste Management Co., SKB. SKB is the owner of CLAB, the central facility for interim storage of spent nuclear fuel, located at Oskarshamn. CLAB was taken into operation in July 1985 and to the end of 1991 in total 1514 tonnes of spent fuel (measured as uranium) have been received. Transportation from the nuclear sites to CLAB is made by a special ship, M/S Sigyn. At Forsmark the final repository for Radioactive Waste (SFR) was taken into operation in April 1988. The repository is situated in crystalline rock under the Baltic Sea. The first construction phase includes rock caverns for 60000 m 3 of waste. A second phase for additional 30000 m 3 is planned to be built and commissioned around the year 2000. At the end of 1991 a total of 7900 m 3 of waste have been deposited in SFR. SKB is in charge of a comprehensive research and development programme on geological disposal of nuclear waste. The total cost for R and D during 1991 was 182.7 MSEK of which 15.9 MSEK came from participants outside Sweden. Geological site-investigations are a substantial part of the programme. SKB is also the managing participant of the international Stripa-project under OECD/NEA. Cost calculations for the total nuclear waste management system, including decommissioning of all reactors, are updated annually. The total cost is estimated to 55 billion SEK. SKB also handles matters pertaining to prospecting and enrichment as well as stockpiling of uranium as strategic reserves for the Swedish nuclear power industry. Consulting service from SKB and associated expert groups are available on a commercial basis. Information activities are an integrated and important part of the Swedish radioactive waste management system. During 1991 successful public information activities have been carried out using mobile exhibitions in a tailor-made trailer and on the SKB ship M/S Sigyn. (au)

Characterizing Sleep Issues Using Twitter.

Science.gov (United States)

McIver, David J; Hawkins, Jared B; Chunara, Rumi; Chatterjee, Arnaub K; Bhandari, Aman; Fitzgerald, Timothy P; Jain, Sachin H; Brownstein, John S

2015-06-08

Sleep issues such as insomnia affect over 50 million Americans and can lead to serious health problems, including depression and obesity, and can increase risk of injury. Social media platforms such as Twitter offer exciting potential for their use in studying and identifying both diseases and social phenomenon. Our aim was to determine whether social media can be used as a method to conduct research focusing on sleep issues. Twitter posts were collected and curated to determine whether a user exhibited signs of sleep issues based on the presence of several keywords in tweets such as insomnia, "can't sleep", Ambien, and others. Users whose tweets contain any of the keywords were designated as having self-identified sleep issues (sleep group). Users who did not have self-identified sleep issues (non-sleep group) were selected from tweets that did not contain pre-defined words or phrases used as a proxy for sleep issues. User data such as number of tweets, friends, followers, and location were collected, as well as the time and date of tweets. Additionally, the sentiment of each tweet and average sentiment of each user were determined to investigate differences between non-sleep and sleep groups. It was found that sleep group users were significantly less active on Twitter (P=.04), had fewer friends (Pcost-effective, and customizable data to be gathered.

Ethical issues faced by clinician/managers in resource-allocation decisions.

Science.gov (United States)

Lemieux-Charles, L; Meslin, E M; Aird, C; Baker, R; Leatt, P

1993-01-01

This article explores the ethical issues faced by clinicians with management responsibilities (clinician/managers) when making decisions related to resource allocation and utilization at a Canadian teaching hospital. Using a focus group method, 28 individuals participated in four homogeneous groups that included nurse managers, managers from other professional groups, and physician managers. Ethical issues that recurred throughout the discussions included fairness, concern with preventing harm, consumer/patient choice, balancing needs of different groups of patients, conflict between financial incentives and patient needs, and professional autonomy. The particular issue of conflict is analyzed from two perspectives--a theory of professional-bureaucratic roles and of obligation--that illustrate how both management and philosophical issues are related. The findings suggest that decentralizing resource allocation and utilization decisions does raise ethical issues for clinician/managers and that a better understanding of these issues can be obtained using an interdisciplinary perspective.

Regulatory analysis for USI A-1, Water Hammer

International Nuclear Information System (INIS)

Serkiz, A.W.

1984-03-01

This is the staff's regulatory analysis dealing with the resolution of the Unresolved Safety Issue A-1, Water Hammer. This report contains the value-impact analysis for this issue, public comments received, and staff response, or action taken, in response to those comments. The staff's technical findings regarding water hammer in nuclear power plants are contained in NUREG-0927

Students' Rights in Mississippi on Matters of Dress and Grooming.

Science.gov (United States)

Robbins, Jerry H.

In the past few years numerous cases have appeared before the courts concerning the dress and grooming of students. In many of these cases, the issue has been related to male students' hair length. Throughout the nation, conflicting trends have emerged from a legal point of view, and the issues remain largely unresolved. This paper discusses the…

Workplace Demographics and Technology: Challenges and Opportunities to the Campus Mission Including the Top Facilities Issues. APPA Thought Leaders 2011

Science.gov (United States)

APPA: Association of Higher Education Facilities Officers, 2011

2011-01-01

It is not unusual in higher education circles to talk about issues affecting the campus. Experts might write about how shifting demographics are changing the campus, or say technology is becoming more pervasive on campus. The campus itself evolves alongside pedagogical practices, technological innovations, student needs, and the mission of the…

What Counts as a 'Social and Ethical Issue' in Nanotechnology?

OpenAIRE

Bruce V. Lewenstein

2005-01-01

As 'social and ethical issues' becomes a recurring phrase in the community paying attention to nanotechnology research, a crucial question becomes: what counts as a social and ethical issue? A typical list includes privacy, environmental health and safety, media hype, and other apparently unrelated issues. This article surveys those issues and suggests that concerns about fundamental concepts of ethics, such as fairness, justice, equity, and especially power, unite the various issues identifi...

Fusion Canada issue 9

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-11-01

A short bulletin from the National Fusion Program. Included in this issue is a report on availability of Canadian Tritium, an ITER update, a CCFM update on Tokamak and the new team organization, an international report on Fusion in Canada and a Laser Fusion Project at the University of Toronto. 3 figs.

Fusion Canada issue 17

International Nuclear Information System (INIS)

1992-05-01

A short bulletin from the National Fusion Program. Included in this issue is a report on increased funding for the Canadian Fusion Program, news of the compact Toroid fuelling gun, an update on Tokamak de Varennes, the Canada - U.S. fusion meeting, measurements of plasma flow velocity, and replaceable Tokamak divertors. 4 figs

Fusion Canada issue 17

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-05-01

A short bulletin from the National Fusion Program. Included in this issue is a report on increased funding for the Canadian Fusion Program, news of the compact Toroid fuelling gun, an update on Tokamak de Varennes, the Canada - U.S. fusion meeting, measurements of plasma flow velocity, and replaceable Tokamak divertors. 4 figs.

Fusion Canada issue 9

International Nuclear Information System (INIS)

1989-11-01

A short bulletin from the National Fusion Program. Included in this issue is a report on availability of Canadian Tritium, an ITER update, a CCFM update on Tokamak and the new team organization, an international report on Fusion in Canada and a Laser Fusion Project at the University of Toronto. 3 figs

Liability Issues

International Nuclear Information System (INIS)

O’Donoghue, K.

2016-01-01

Nuclear liability conventions try to provide a set of rules to govern third party liability. Not all States are parties to one of the existing liability conventions. There are a number of reasons why individual States may choose not to join one of the existing conventions. These include limits of compensation, jurisdiction issues, complexity, cost and definition of damage among others. This paper looks at the existing conventions and identifies some of the main issues in the existing conventions which prevent some States from signing them. The paper attempts to tease out some of the perceived gaps in the existing conventions and give a brief description of the reasons why non-Contracting Parties have difficulty with the provisions of the conventions. The paper recognizes that there has been work done in this area previously by the International Expert Group on Nuclear Liability (INLEX) and others to try to develop the existing frameworks to enhance global adherence by nuclear and non-nuclear States to an effective nuclear liability regime. (author)

Personalized medicine and the role of health economics and outcomes research: issues, applications, emerging trends, and future research.

Science.gov (United States)

O'Donnell, John C

2013-01-01

The decade since the completion of the sequencing of the human genome has witnessed significant advances in the incorporation of genomic information in diagnostic, treatment, and reimbursement practices. Indeed, as case in point, there are now several dozen commercially available genomic tests routinely applied across a wide range of disease states in predictive or prognostic applications. Moreover, many involved in the advancement of personalized medicine would view emerging approaches to stratify patients in meaningful ways beyond genomic information as a signal of the progress made. Yet despite these advances, there remains a general sense of dissatisfaction about the progress of personalized medicine in terms of its contribution to the drug development process, to the efficiency and effectiveness of health care delivery, and ultimately to the provision of the right treatment to the right patient at the right time. Academicians, payers, and manufacturers alike are struggling not only with how to embed the new insights that personalized medicine promises but also with the fundamental issues of application in early drug development, implications for health technology assessment, new demands on traditional health economic and outcomes research methods, and implications for reimbursement and access. In fact, seemingly prosaic issues such as the definition and composition of the term "personalized medicine" are still unresolved. Regardless of these issues, practitioners are increasingly compelled to find practical solutions to the challenges and opportunities presented by the evolving face of personalized medicine today. Accordingly, the articles comprising this Special Issue offer applied perspectives geared toward professionals and policymakers in the field grappling with developing, assessing, implementing, and reimbursing personalized medicine approaches. Starting with a framework with which to characterize personalized medicine, this Special Issue proceeds to

Fusion Canada issue 14

International Nuclear Information System (INIS)

1991-05-01

A short bulletin from the National Fusion Program. Included in this issue is a report on a fusion cooperation agreement between Japan and Canada, an update at Tokamak de Varennes on plasma biasing experiments and boronization tests and a collaboration between Canada and the U.S. on a compact toroid fuelling gun. 4 figs

Challenges and prospects of using information technologies in higher education

Directory of Open Access Journals (Sweden)

Frolov Alexander

2016-01-01

Full Text Available The considerable attention is paid to information technologies in system of the higher education now. Using the latest technology, software and hardware in the learning process allows achieving high outcomes quality of study. The article deals with modern teaching technologies, including distance learning technology, case-technology, which is already used in practice in higher education. There remain unresolved issues of effective use of new learning technologies, the quality of the used software and hardware. The perspective directions of development of informatization of education are defined.

Development of Readout Interconnections for the Si-W Calorimeter of SiD

Energy Technology Data Exchange (ETDEWEB)

Woods, M.; Fields, R.G.; Holbrook, B.; Lander, R.L.; Moskaleva, A.; Neher, C.; Pasner, J.; Tripathi, M.; /UC, Davis; Brau, J.E.; Frey, R.E.; Strom, D.; /Oregon U.; Breidenbach, M.; Freytag, D.; Haller, G.; Herbst, R.; Nelson, T.; /SLAC; Schier, S.; Schumm, B.; /UC, Santa Cruz

2012-09-14

The SiD collaboration is developing a Si-W sampling electromagnetic calorimeter, with anticipated application for the International Linear Collider. Assembling the modules for such a detector will involve special bonding technologies for the interconnections, especially for attaching a silicon detector wafer to a flex cable readout bus. We review the interconnect technologies involved, including oxidation removal processes, pad surface preparation, solder ball selection and placement, and bond quality assurance. Our results show that solder ball bonding is a promising technique for the Si-W ECAL, and unresolved issues are being addressed.

Confinement and heating of high beta plasma with emphasis on compact toroids. Compact toroid research

International Nuclear Information System (INIS)

Vlases, G.C.; Pietrzyk, Z.A.

1984-11-01

Two older projects associated with very high energy density plasmas, specifically the High Density Field Reversed Configuration and the Liner Plasma Compression Experiment, have been completed. Attention has been turned to compact toroid experiments of more conventional density, and three experiments have been initiated. These include the Coaxial Slow Source Experiment, the Variable Length FRC Experiment, and Variable Angle CthetaP Experiment. In each case, the project was begun in order to provide basic plasma physics information on specific unresolved issues of progammatic importance to the national CT Program

10 CFR 905.11 - What must an IRP include?

Science.gov (United States)

2010-01-01

..., energy conservation and efficiency, cogeneration and district heating and cooling applications, and..., consumer preferences, environmental impacts, demand or energy impacts, implementation issues, revenue... 10 Energy 4 2010-01-01 2010-01-01 false What must an IRP include? 905.11 Section 905.11 Energy...

A comparison of ethical issues in nursing practice across nursing units.

Science.gov (United States)

Park, Mihyun; Jeon, Sang Hee; Hong, Hyun-Ja; Cho, Sung-Hyun

2014-08-01

The complexity and variety of ethical issues in nursing is always increasing, and those issues lead to special concerns for nurses because they have critical impacts on nursing practice. The purpose of this study was to gather comprehensive information about ethical issues in nursing practice, comparing the issues in different types of nursing units including general units, oncology units, intensive care units, operating rooms, and outpatient departments. The study used a descriptive research design. Ethics/human rights issues encountered by nurses in their daily nursing practice were identified by using the Ethical Issues Scale. The study sample included 993 staff nurses working in a university hospital in South Korea. This study was approved by the University Institutional Review Board. Completed questionnaires were returned sealed with signed informed consent. The most frequently and disturbingly encountered issues across nursing units were "conflicts in the nurse-physician relationship," "providing care with a possible risk to your health," and "staffing patterns that limit patient access to nursing care." The findings of this study showed that nurses from different nursing units experienced differences in the types or frequency of ethical issues. In particular, intensive care units had the greatest means of all the units in all three component scales including end-of-life treatment issues, patient care issues, and human rights issues. Nurses experienced various ethical challenges in their daily practice. Of the ethical issues, some were distinctively and frequently experienced by nurses in a specific unit. This study suggested that identifying and understanding specific ethical issues faced by nurses in their own areas may be an effective educational approach to motivate nurses and to facilitate nurses' reflection on their experiences. © The Author(s) 2014.

State of the Art, Unresolved Issues, and Future Research Directions in the Fight against Hepatitis C Virus: Perspectives for Screening, Diagnostics of Resistances, and Immunization

Directory of Open Access Journals (Sweden)

Cecilia Trucchi

2016-01-01

Full Text Available Hepatitis C virus (HCV still represents a major public health threat, with a dramatic burden from both epidemiological and clinical points of view. New generation of direct-acting antiviral agents (DAAs has been recently introduced in clinical practice promising to cure HCV and to overcome the issues related to the interferon-based therapies. However, the emergence of drug resistance and the suboptimal activity of DAAs therapies against diverse HCV genotypes have been observed, determining treatment failure and hampering an effective control of HCV spread worldwide. Moreover, these treatments remain poorly accessible, particularly in low-income countries. Finally, effective screening strategy is crucial to early identifying and treating all HCV chronically infected patients. For all these reasons, even though new drugs may contribute to impacting HCV spread worldwide a preventive HCV vaccine remains a cornerstone in the road to significantly reduce the HCV spread globally, with the ultimate goal of its eradication. Advances in molecular vaccinology, together with a strong financial, political, and societal support, will enable reaching this fundamental success in the coming years. In this comprehensive review, the state of the art about these major topics in the fight against HCV and the future of research in these fields are discussed.

Access control issues and solutions for large sites

International Nuclear Information System (INIS)

Warren, F.E.

1992-07-01

The Lawrence Livermore National Laboratory (LLNL) operates an automated access control system consisting of more than 100 portals. We have gained considerable practical experience in the issues involved in operating this large system, and have identified the central issues to include system reliability, the large user population, the need for central control, constant change, high visibility and the budget. This paper outlines these issues and draws from our experience to discuss some fruitful ways of addressing them

U.S. NRC's generic issues program

International Nuclear Information System (INIS)

Kauffman, J.V.; Foster, J.W.

2008-01-01

The United States Nuclear Regulatory Commission (NRC) has a Generic Issues Program (GIP) to address Generic Issues (GI). A GI is defined as 'a regulatory matter involving the design, construction, operation, or decommissioning of several, or a class of, NRC licensees or certificate holders that is not sufficiently addressed by existing rules, guidance, or programs'. This rather legalistic definition has several practical corollaries: First, a GI must involve safety. Second, the issue must involve at least two plants, or it would be a plant-specific issue rather than a GI. Third, the potential safety question must not be covered by existing regulations and guidance (compliance). Thus, the effect of a GI is to potentially change the body of regulations and associated guidance (e.g., regulatory guides). The GIP was started in 1976, thus it is a relatively mature program. Approximately 850 issues have been processed by the program to date. More importantly, even after 30 years, new GIs continue to be proposed. The entire set of Generic Issues (GIs) is updated annually in NUREG-0933, 'A Prioritization of Generic Safety Issues'. GIs normally involve complex questions of safety and regulation. Efficient and effective means of addressing these issues are very important for regulatory effectiveness. If an issue proves to pose a genuine, significant safety question, then swift, effective, enforceable, and cost-effective action needs to be taken. Conversely, if an issue is of little safety significance, the issue should be dismissed in an expeditious manner, avoiding unnecessary expenditure of resources and regulatory burden or uncertainty. This paper provides a summary of the 5-stage program, from identification through the regulatory assessment stage. The paper also includes a discussion of the program's seven criteria, sources of proposed GIs, recent improvements, publicly available information, historical performance, and status of current GIs. (authors)

Gynaecological issues affecting the obese adolescent.

Science.gov (United States)

Wood, Paul L; Bauman, Dvora

2015-05-01

The implications of obesity in childhood and adolescence resonate into adulthood and have implications at different levels that include psychosocial and health issues that impact beyond reproductive performance. This chapter explores the various facets and consequences on gynaecological issues of increased Body Mass Index in childhood, including the link with puberty, pubertal menorrhagia (also affecting children with complex needs) and the all too common problems surrounding hyperandrogenism, insulin resistance and the polycystic ovarian syndrome in particular which need to be seen in the specific context of the adolescent years. The wider ramifications of obesity on the psychosocial welfare of adolescents merits special attention. Finally management strategies are considered in the context of the needs of adolescents. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

Intellectual Property and Copyright Issues in Online Learning Environments.

Science.gov (United States)

Szanto, Edit

2001-01-01

Provides an overview of intellectual property and copyright issues as they relate to online learning environments. Includes a historical perspective; laws and regulations; liability; Web-related issues; higher education; distance learning; compliance strategies; and policy recommendations. (Author/LRW)

Towards assessing the social sustainability performance of the petroleum industry in the Niger Delta Region of Nigeria

CSIR Research Space (South Africa)

Bubou, GM

2009-05-01

Full Text Available Unresolved social issues between the local community and the petroleum industry plague the Niger Delta Region of Nigeria. These concerns are addressed by introducing a social sustainability assessment framework for the petroleum industry. Key...

CRISPR and the Rebirth of Synthetic Biology

NARCIS (Netherlands)

Heidari, Raheleh; Shaw, David Martin; Elger, Bernice Simone

Emergence of novel genome engineering technologies such as clustered regularly interspaced short palindromic repeat (CRISPR) has refocused attention on unresolved ethical complications of synthetic biology. Biosecurity concerns, deontological issues and human right aspects of genome editing have

Fusion Canada issue 16

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-01-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Ontario Hydro`s contract for tritium supply from Germany, a CCFM update on plasma biasing, divertor operation, radiofrequency plasma current drive and the plasma heating system for the Tokamak de Varennes, and an agreement for ITER engineering design activities. 5 figs.

Fusion Canada issue 18

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-08-01

A short bulletin from the National Fusion Program. Included in this issue is a report on the ITER agreement signed with the EDA, the robotic maintenance for NET, the CFFTP Fusion Pilot Study, the new IEA joint programs on environment, safety and economic aspects of fusion power, and a review by the CCFM advisory committee. 3 figs.

Fusion Canada issue 18

International Nuclear Information System (INIS)

1992-08-01

A short bulletin from the National Fusion Program. Included in this issue is a report on the ITER agreement signed with the EDA, the robotic maintenance for NET, the CFFTP Fusion Pilot Study, the new IEA joint programs on environment, safety and economic aspects of fusion power, and a review by the CCFM advisory committee. 3 figs

Fusion Canada issue 19

International Nuclear Information System (INIS)

1992-12-01

A short bulletin from the National Fusion Program. Included in this issue is a report on the IAEA Plasma Biasing Meeting, the new IEA program -Nuclear Technology of Fusion reactors, TFTR tritium purification system, an update by CCFM on machine additions and modifications, and news of a new compact Toroid injector at the University of Saskatchewan. 1 fig

Fusion Canada issue 16

International Nuclear Information System (INIS)

1992-01-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Ontario Hydro's contract for tritium supply from Germany, a CCFM update on plasma biasing, divertor operation, radiofrequency plasma current drive and the plasma heating system for the Tokamak de Varennes, and an agreement for ITER engineering design activities. 5 figs

Editorial: AABFJ Volume 9, Issue 1, 2015

Directory of Open Access Journals (Sweden)

Monir Mir

2015-03-01

Full Text Available There are six excellent and diversified papers published in this edition of the Australasian Accounting, Business and Finance Journal. As highlighted below, these papers’ contributions range from issues relating to accounting standard setting process to the efficient market hypothesis including a paper based on alternative accounting research methodology that explores the issues of career choices by women in a developing economy.

Systematic evaluation program. Status report and initial evaluation

International Nuclear Information System (INIS)

1983-06-01

The MHB Ongoing Systematic Evaluation Program (SEP) Assessment Study was initiated by the Swedish Nuclear Power Inspectorate (SKI) in 1980. This MHB report is a status report and initial evaluation of SEP. The methodology and results of SEP are disscused with particular emphasis on the first two SEP plant reviews - the Palisades and R.E. Ginna nuclear power plants. The comments of cognizant persons in the NRC and the ACRS, as well as private consultants, are included herein. MHBs major findings are as follows: The SEP plant review methodology was acceptable to the NRC Commissioners, the ACRS, and the NRC Staffs consultants who evaluated the first two SEP plant reviews. A concern raised by all who commented on SEP was the absence of Three Mile Island Action Plan Items and Unresolved Safety Issues from current SEP reviews. The SEP reviews of the Palisades and R.E. Ginna plants concluded that the two plant designs were adequate with respect to a majority of safety topics. Several topics remain unresolved in both the Palisades and R.E. Ginna SEP reviews. In the case of the Ginna plant, several related topics have been grouped together in a major structural reevaluation study. In general, due to the number of unresolved and excluded topics, SEP has not at this time produced a plant safety evaluation which can be considered complete and integrated. (author)

Socioeconomic and political issues in radiology

International Nuclear Information System (INIS)

Stiles, R.G.; Belt, H.C.

1990-01-01

This paper compares editorials on socioeconomic and political issues published in the radiologic literature during 1920-1940 with those published during 1970-1990. Radiologists literature indexes were searched for editorials on socioeconomic and political issues published during two 20-year periods: 1920-1940 and 1970- 1990. One hundred editorials from each period were chosen from two major journals. The editorials were organized into 20 categories including turf, subspecialization, radiologist as physician, public relations, governmental intervention (socialized medicine), future of radiology, overuse of studies

Venturing into cyberspace - some legal issues

International Nuclear Information System (INIS)

Gahtan, A.M.

1999-01-01

Issues regarding the use of the world-wide web by oil and gas companies were discussed. A series of overhead viewgraphs were used to illustrate general advertising and promotion issues including liability for links and frames, web site development agreements, and web site hosting agreements. The meaning of industry or product-specific advertising, trade mark infringement implications, the significance of foreign jurisdictions in operating a website, other significant website concepts, and the general principles of website development and attendant legal implications are explored

40 CFR 1502.14 - Alternatives including the proposed action.

Science.gov (United States)

2010-07-01

... impacts of the proposal and the alternatives in comparative form, thus sharply defining the issues and... action so that reviewers may evaluate their comparative merits. (c) Include reasonable alternatives not... identify such alternative in the final statement unless another law prohibits the expression of such a...

War in former Yugoslavia: Coping with Nutritional Issues

DEFF Research Database (Denmark)

Robertson, Aileen; James, W. Philip. T.

1998-01-01

of food supply; anthropometric measures; in search of the most vulnerable; assessing food security; assessing nutritional deficiencies-protein and micronutrient issues; public health issues in former Yugoslavia-infant feeding practices, developing nutrition expertise in modern public health......This chapter in the text book "Essentials of Human Nutrition" published by OUP explores war in former Yugoslavia and the accompanying nutritional issues. Areas of focus include: emergency food aid; how much energy?; nutritional surveillance-a re-evaluation of its role in wartime; the quality...

Introduction to Open Praxis volume 8 issue 3

Directory of Open Access Journals (Sweden)

Inés Gil-Jaurena

2016-08-01

Full Text Available This third Open Praxis issue in 2016 is an open issue that includes six research papers and one book review. If this introduction I would like to deepen in the role of the Editorial team and present our Editorial Board past and current members, partially renewed in July 2016.

Ethical issues experienced by healthcare workers in nursing homes: Literature review.

Science.gov (United States)

Preshaw, Deborah Hl; Brazil, Kevin; McLaughlin, Dorry; Frolic, Andrea

2016-08-01

Ethical issues are increasingly being reported by care-providers; however, little is known about the nature of these issues within the nursing home. Ethical issues are unavoidable in healthcare and can result in opportunities for improving work and care conditions; however, they are also associated with detrimental outcomes including staff burnout and moral distress. The purpose of this review was to identify prior research which focuses on ethical issues in the nursing home and to explore staffs' experiences of ethical issues. Using a systematic approach based on Aveyard (2014), a literature review was conducted which focused on ethical and moral issues, nurses and nursing assistants, and the nursing home. The most salient themes identified in the review included clashing ethical principles, issues related to communication, lack of resources and quality of care provision. The review also identified solutions for overcoming the ethical issues that were identified and revealed the definitional challenges that permeate this area of work. The review highlighted a need for improved ethics education for care-providers. © The Author(s) 2015.

Summary of papers included within this commemorative issue

Czech Academy of Sciences Publication Activity Database

Roček, Zbyněk

2016-01-01

Roč. 72, 1/2 (2016), s. 15-16 ISSN 2533-4050 Institutional support: RVO:67985831 Keywords : paleontology * summmary Subject RIV: DB - Geology ; Mineralogy http://www.nm.cz/publikace/archiv-en.php?id=4&rok=72&kcislu=1-2&f_=Show

BWR feedwater nozzle and control-rod-drive return line nozzle cracking

International Nuclear Information System (INIS)

Anon.

1981-01-01

In its 1978 Annual Report to Congress, the Nuclear Regulatory Commission identified as an unresolved safety issue the appearance of cracks in feedwater nozzles at boiling-water reactors (BWRs). Later similar cracking, detected in return water lines for control-rod-drive systems at BWRs, was designated Part II of the issue. This article outlines the resolution of these cracking problems

Sustainable energy issues in developing countries

Energy Technology Data Exchange (ETDEWEB)

Munasinghe, M [Environmental Policy Division, The World Bank, Washington D.C. (US)

1991-07-01

Increased energy use is a vital pre-requisite for economic development, and less developing countries (LDCs) are struggeling to meet energy needs at acceptable costs. LDC decision-makers share the worldwide environmental concerns, but also face other urgent issues like poverty. The industrialised countries can afford to substitute environmental protection for further material growth, but the LDCs will need concessional funding to participate in addressing global environmental problems. Global financing issues may be analysed and resolved through tradeoffs among several criteria including affordability/additionality, fairness/equity, and economic efficiency. The short-term LDC response to sustainable energy issues will be limited mainly to conventional technologies in efficiency improvements, conservation and resource development. The industrialised nations should provide financial resources to LDCs and develop the technology to be used in the 21st century. Pilot international funds like the Global Environmental Facility and the Ozone Fund will help LDCs participate in the effort to solve global environmental issues. (author) 16 refs.

Long-Range Research Plan, FY 1985-FY 1989

International Nuclear Information System (INIS)

1984-09-01

The Long-Range Research Plan (LRRP) was prepared by the Office of Nuclear Regulatory Research (RES) to assist the NRC in coordinating its long-range research planning with the short-range budget cycles. The LRRP lays out programmatic approaches for research to help resolve regulatory issues. The plan will be updated annually. This document is divided into the following sections: operating reactor inspection, maintenance, and repair; equipment qualification; seismic research; reactor operations and risk; thermal-hydraulic transients; severe accidents; advanced concepts; radiation protection and health effects; and waste management. The following are also listed as appendices: unresolved safety issues and TMI action plan items, priorities for research program, research program outline, and research utilization report. A glossary of acronyms is included

Research Collaboration in a Communication Rights Campaign: Lessons Learned.

Science.gov (United States)

Ryan, Charlotte

2018-01-01

In building public support for social change, activists in communities of color routinely approach broader audiences via news media. Communities of color, however, routinely face disparities that limit their access to media including local news media outlets. This lack of access mirrors inequalities in political, social, and economic arenas and can slow public awareness campaigns to address disparities in health, environmental, and other quality-of-life issues. I describe two community-based collaborative action research studies that documented and challenged how local television newscasts underrepresented and misrepresented three communities of color in Boston. The linkage between communication rights and campaigns to address quality-of-life issues is presented, as well as unresolved challenges in the collaborative research process. The study has implications for environmental health campaigns.

USSR Space Life Sciences Digest, issue 29

Science.gov (United States)

Stone, Lydia Razran (Editor); Teeter, Ronald (Editor); Rowe, Joseph (Editor)

1991-01-01

This is the twenty-ninth issue of NASA's Space Life Sciences Digest. It is a double issue covering two issues of the Soviet Space Biology and Aerospace Medicine Journal. Issue 29 contains abstracts of 60 journal papers or book chapters published in Russian and of three Soviet monographs. Selected abstracts are illustrated with figures and tables from the original. A review of a book on environmental hygiene and a list of papers presented at a Soviet conference on space biology and medicine are also included. The materials in this issue were identified as relevant to 28 areas of space biology and medicine. The areas are: adaptation, aviation medicine, biological rhythms, body fluids, botany, cardiovascular and respiratory systems, developmental biology, digestive system, endocrinology, equipment and instrumentation, genetics, habitability and environment effects, hematology, human performance, immunology, life support systems, mathematical modeling, metabolism, musculoskeletal system, neurophysiology, nutrition, personnel selection, psychology, radiobiology, reproductive system, space biology and medicine, and the economics of space flight.

Special issue on the spectroscopy of transient plasmas

Science.gov (United States)

Bailey, James; Hoarty, David; Mancini, Roberto; Yoneda, Hitoki

2015-01-01

Experimental and theoretical papers are invited for a special issue of Journal of Physics B: Atomic, Molecular and Optical Physics on Spectroscopy of Transient Plasmas, covering plasma conditions produced by pulsed laboratory sources including for example, short and long pulse lasers; pulsed power devices; FELs; XFELs and ion beams. The full range of plasma spectroscopy from the optical range up to high energy bremsstrahlung radiation will be covered. The deadline for submitting to this special issue is 1 March 2015. (Expected web publication: autumn 2015). Late submissions will be considered for the journal, but may not be included in the special issue. All submitted articles will be fully refereed to the journal's usual high standards. Upon publication, the issue will be widely promoted to the atomic, molecular and optical physics community, ensuring that your work receives maximum visibility. Articles should be submitted at http://mc04.manuscriptcentral.com/jphysb-iop. Should you have any questions regarding the preparation of manuscripts or the suitability of your work for this Issue, please do not hesitate to contact the J. Phys. B: At. Mol. Opt. Editorial team (jphysb@iop.org). We look forward to hearing from you and hope that we can welcome you as a contributing author.

P270: Factors associated with fall rate in psychogeriatric residents

NARCIS (Netherlands)

Kosse, N.M.; de Groot, Maartje H; Hortobágyi, T.; Lamoth, C.J.C.

2014-01-01

Introduction: Falls in psychogeriatric residents represent a costly but unresolved safety issue. Identifying fall risk factors and their inter-relationship may help to individualize prevention programs and increase the effectiveness. Therefore, we aimed to examine the relationship between patient

Census 2001: issues and perspectives.

Science.gov (United States)

1998-01-01

This article discusses the Census of India for 2001 and gender issues such as the sex ratio, undercounts of girls, tribe and scheduled caste data, and the data users' conference. The April 1998 conference was attended by representatives of government planning and development departments, research institutions, and statisticians and researchers. Under consideration was a government Ministry of Welfare proposal to reintroduce, after a 60-year hiatus, data by scheduled caste and tribe. This issue is complicated by criteria that vary by state and includability. Quotas for backward classes in educational institutions, government jobs, and in decision-making bodies are the reason for designations by caste. Some groups are distressed because of lack of inclusion as backward classes. M.N. Srinivas strongly advises that counting by caste will create problems for enumerators and will result in lawsuits and violent disturbances. G. Shah argues that caste counts will not weaken the caste system nor expand their political power, but will intensify internal conflicts between the Dalit and Bahujan movements. One other issue is the reintroduction of the 1961 Household schedule which provides family composition by landholding size and household enterprise. Krishnaji advises that this data would help analyze sex ratio imbalances. In 1997, the Core Group examined gender equity issues and operational issues about increasing the scope without increasing costs. The Core Group recommended caste data at the district and sub-district level. Undercounting of the female work force is a continuing issue from the 1991 Census. Suggestions by the Core Group are indicated in brief.

Electric power monthly, September 1990. [Glossary included

Energy Technology Data Exchange (ETDEWEB)

1990-12-17

The purpose of this report is to provide energy decision makers with accurate and timely information that may be used in forming various perspectives on electric issues. The power plants considered include coal, petroleum, natural gas, hydroelectric, and nuclear power plants. Data are presented for power generation, fuel consumption, fuel receipts and cost, sales of electricity, and unusual occurrences at power plants. Data are compared at the national, Census division, and state levels. 4 figs., 52 tabs. (CK)

Unresolved Issues and New Challenges in Teaching English to Young Learners: The Case of South Korea

Science.gov (United States)

Garton, Sue

2014-01-01

The introduction of languages, especially English, into the primary curriculum around the world has been one of the major language-in-education policy developments in recent years. In countries where English has been compulsory for a number of years, the question arises as to what extent the numerous and well-documented challenges faced by the…

An Overview of School Dropout in Central America: Unresolved Issues and New Challenges for Education Progress

Science.gov (United States)

Adelman, Melissa A.; Székely, Miguel

2017-01-01

School dropout is a growing concern in Central America, and in Latin America as a whole, because of its consequences for economic productivity, the inclusiveness of growth, social cohesion, and increasing youth risks. This paper utilizes more than two decades of household survey data to construct a systematic overview of school dropout at the…

Intellectual property issues in holography and high tech

Science.gov (United States)

Reingand, Nadya

2004-06-01

The author with technical education background (Ph.D. in holography) shares her 3+ years of experience working on intellectual property (IP) issues that includes patents, trademarks, and copyrights. A special attention is paid to the patent issues: the application procedure, the patent requirements, the databases for prior art search, how to make the cost efficient filing.

Legal issues in cash balance pension plan conversions.

Science.gov (United States)

Forman, J B

2001-01-01

Replacing a traditional pension with a cash balance plan raises a number of complicated and unsettled legal issues, including the protection of accrued benefits, the rate of benefit accrual, age discrimination and notice requirements. This article discusses those issues and concludes that routine conversions to cash balance plans appear to be legal both currently and into the foreseeable future.

Legal Issues in Educational Technology: Implications for School Leaders.

Science.gov (United States)

Quinn, David M.

2003-01-01

Discusses several legal issues involving the use of educational technology: Freedom of speech, regulation of Internet material harmful to minors, student-developed Web pages, harassment and hostile work environment, staff and student privacy, special education, plagiarism, and copyright issues. Includes recommendations for addressing technology…

Unpacking the burden: gender issues in anaesthesia.

Science.gov (United States)

Strange Khursandi, D C

1998-02-01

A survey carried out by the Australian Society of Anaesthetists explored gender issues in the personal and professional lives of anaesthetists. Issues highlighted include training and career paths, combining anaesthetic training with domestic responsibilities, personal relationships, pregnancy and childrearing, private practice, part-time work, parental leave, the single anaesthetist, doctor spouses, sexual harassment, and negative attitudes in colleagues. Particular problems were identified in the training years, in part-time work, in private practice, and in combining parental and domestic responsibilities with a career in anaesthesia. Strategies to address relevant issues are discussed, with reference to the increasing proportion of women in medicine and anaesthesia.

Transmission issues in Alberta

International Nuclear Information System (INIS)

Levson, D.

2002-01-01

This paper outlined the major issues and concerns facing users of the transmission system in Alberta. They include congestion management issues that make investors uncertain about power generation. It is necessary to know the difference between which transmission price signals will be faced by low cost cogeneration at Fort McMurray and Cold Lake coal-fired generation near Edmonton compared to combined cycle gas generation near Calgary. Import and export policy tariffs are another concern. Most new generation opportunities in Alberta require access to export markets, but transmission facilities for export need policy support and appropriate tariffs. It was noted that the past actions of Alberta's Transmission Administrator and balancing pool may be distorting market signals for ancillary service markets, and that loss studies and calculations need upgrading

Malaysian Serials: Issues and Problems.

Science.gov (United States)

Bahri, Che Norma

This paper analyzes the issues and problems while looking at the trends and developments of serials publishing in Malaysia. The first section provides background; topics addressed include the country and people of Malaysia, the history of serials publishing in Malaysia, categories and formats of serials publishing, academic publications,…

Response to Key Issues Raised in the Post-14 Mathematics Inquiry

Science.gov (United States)

Burghes, David; Hindle, Mike

2004-01-01

This article is a detailed response to the issues raised by the Post-14 Mathematics Inquiry in the UK. It aims to debate some of the central issues in mathematics teaching in the UK, including recruitment and retention of mathematics teachers, the curriculum content, national assessment, teaching resources (including ICT) and national strategies…

Ethical Issues in Sports Medicine

OpenAIRE

Greenfield, Bruce H.; West, Charles Robert

2012-01-01

Ethical issues present a challenge for health care professionals working with athletes of sports teams. Health care professionals?including the team physician, the physical therapist, and the athletic trainer?are faced with the challenge of returning an athlete to competition as quickly as possible but as safely as possible. Conflicts of interest arise due to conflicting obligations of the team physician to the athlete and other members of the sports organization, including coaches and the te...

Moving from deterministic towards probabilistic coastal hazard and risk assessment: Development of a modelling framework and application to Narrabeen Beach, New South Wales, Australia, doi: 10.1016/j.coastaleng.2014.11.009

NARCIS (Netherlands)

Wainwright, D.J.; Ranasinghe, Ranasinghe W M R J B; Callaghan, D.P.; Woodroffe, C.D.; Jongejan, R.; Dougherty, A.J.; Rogers, K.; Cowell, P.J.

2015-01-01

Traditional methods for assessing coastal hazards have not typically incorporated a rigorous treatment of uncertainty. Such treatment is necessary to enable risk assessments which are now required by emerging risk based coastal zone management/planning frameworks. While unresolved issues remain,

Editorial of the Special Issue Antimicrobial Polymers

Directory of Open Access Journals (Sweden)

Iolanda Francolini

2013-09-01

Full Text Available The special issue “Antimicrobial Polymers” includes research and review papers concerning the recent advances on preparation of antimicrobial polymers and their relevance to industrial settings and biomedical field. Antimicrobial polymers have recently emerged as promising candidates to fight microbial contamination onto surfaces thanks to their interesting properties. In this special issue, the main strategies pursued for developing antimicrobial polymers, including polymer impregnation with antimicrobial agents or synthesis of polymers bearing antimicrobial moieties, were discussed. The future application of these polymers either in industrial or healthcare settings could result in an extremely positive impact not only at the economic level but also for the improvement of quality of life.

Open Issues in Object-Oriented Programming

DEFF Research Database (Denmark)

Madsen, Ole Lehrmann

1995-01-01

We discuss a number of open issues within object-oriented programming. The central mechanisms of object-oriented programming appeared with Simula, developed more than 30 years ago; these include class, subclass, virtual function, active object and the first application framework, Class Simulation....... The core parts of object-oriented programming should be well understood, but there are still a large number of issues where there is no consensus. The term object-orientation has been applied to many subjects, such as analysis, design implementation, data modeling in databases, and distribution...

State regulatory issues in acid rain compliance

International Nuclear Information System (INIS)

Solomon, B.D.; Brick, S.

1992-01-01

This article discusses the results of a US EPA workshop for state regulators and commission staff on acid rain compliance concerns. The topics of the article include the results of market-based emissions control, how emissions trading is expected to reduce emissions, public utility commissions approval of compliance plans, the purposes of the workshop, market information, accounting issues, regulatory process and utility planning, multi-state compliance planning, and relationship to other compliance issues

Product Category Management Issues

OpenAIRE

Żukowska, Joanna

2011-01-01

The purpose of the paper is to present the issues related to category management. It includes the overview of category management definitions and the correct process of exercising it. Moreover, attention is paid to the advantages of brand management, the benefits the supplier and retailer may obtain in this way. The risk element related to this topics is also presented herein. Joanna Żukowska

Issues of Financial Assurance of Economy Greening in the Regions

Science.gov (United States)

Shekhova, Natalia V.; Kireeva, Ekaterina E.; Nazarov, Michael A.; Peskova, Dinara R.; Gusakova, Elena P.; Dorozhkin, Vladimir E.

2016-01-01

The relevance of the analyzed issue is caused by the need to internalize environmental externalities in the modern world. The purpose of the article is to examine the issue of financial support of the green economy using the example of the regions included in the Volga Federal District (VFD). The leading methods to the study of this issue is a…

Internet-Mediated Learning in Public Affairs Programs: Issues and Implications.

Science.gov (United States)

Rahm, Dianne; Reed, B. J.; Rydl, Teri L.

1999-01-01

An overview of Internet-mediated learning in public affairs programs identifies issues for faculty, students, and administrators, including intellectual property rights, instructional issues, learning approaches, student expectations, logistics and support, complexity of coordination, and organizational control. (DB)

Workplace bullying: an emergent issue.

Science.gov (United States)

Essen, S Donovan; Esquivel, Cynthia; Jha, Pankaj

2014-09-01

All companies, including dentists, rely on their staff to represent their firms in the most positive and effective manner. Today's managers face a multitude of issues, and as such, they must walk a fine line of fostering a productive, harmonious and safe working environment for their employees. Over the last several decades it is apparent that on the- job sexual harassment is no longer the leading issue of employee complaints. Rather, the organization issue which was investigated is workplace bullying, also commonly referred to as employee harassment. Risk management is no longer limited to avoiding malpractice issues but also preventing litigation created by poor organizational behavior. The primary purpose of this paper is to explore the background of workplace bullying and how it affects today's managers and their employees, customers and suppliers. In other words, the scope of this paper will feature research on past studies, results and conclusions. Since workplace bullying affects all levels of a corporation, it must be stated that the concern and focus of this paper is for today's manager to understand the background and history of workplace bullying, and what they can do to foster a safe working environment and prevent the bully from creating mental and physical harm to their employees. This paper details the history of workplace bullying and how management, employees and suppliers deal with and address the issue. Lastly, this treatise looks at risk management from a manger/dentist's perspective, the assessment/conclusion summarizes the implications for managers regarding how they must handle the issue or risk harm to the employee and/or serious legal ramifications.

The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas

Directory of Open Access Journals (Sweden)

London Leslie

2010-08-01

Full Text Available Abstract The controversy about the use of data from human volunteer studies involving experimental exposure to pesticides as part of regulatory risk assessment has been widely discussed, but the complex and interrelated scientific and ethical issues remain largely unresolved. This discussion paper, generated by authors who comprised a workgroup of the ICOH Scientific Committee on Rural Health, reviews the use of human experimental studies in regulatory risk assessment for pesticides with a view to advancing the debate as to when, if ever, such studies might be ethically justifiable. The discussion is based on three elements: (a a review of discussion papers on the topic of human testing of pesticides and the positions adopted by regulatory agencies in developed countries; (b an analysis of published and unpublished studies involving human testing with pesticides, both in the peer-reviewed literature and in the JMPR database; and (c application of an ethical analysis to the problem. The paper identifies areas of agreement which include general principles that may provide a starting point on which to base criteria for judgements as to the ethical acceptability of such studies. However, the paper also highlights ongoing unresolved differences of opinion inherent in ethical analysis of contentious issues, which we propose should form a starting point for further debate and the development of guidelines to achieve better resolution of this matter.

The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas.

Science.gov (United States)

London, Leslie; Coggon, David; Moretto, Angelo; Westerholm, Peter; Wilks, Martin F; Colosio, Claudio

2010-08-18

The controversy about the use of data from human volunteer studies involving experimental exposure to pesticides as part of regulatory risk assessment has been widely discussed, but the complex and interrelated scientific and ethical issues remain largely unresolved. This discussion paper, generated by authors who comprised a workgroup of the ICOH Scientific Committee on Rural Health, reviews the use of human experimental studies in regulatory risk assessment for pesticides with a view to advancing the debate as to when, if ever, such studies might be ethically justifiable. The discussion is based on three elements: (a) a review of discussion papers on the topic of human testing of pesticides and the positions adopted by regulatory agencies in developed countries; (b) an analysis of published and unpublished studies involving human testing with pesticides, both in the peer-reviewed literature and in the JMPR database; and (c) application of an ethical analysis to the problem. The paper identifies areas of agreement which include general principles that may provide a starting point on which to base criteria for judgements as to the ethical acceptability of such studies. However, the paper also highlights ongoing unresolved differences of opinion inherent in ethical analysis of contentious issues, which we propose should form a starting point for further debate and the development of guidelines to achieve better resolution of this matter.

The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas

Science.gov (United States)

2010-01-01

The controversy about the use of data from human volunteer studies involving experimental exposure to pesticides as part of regulatory risk assessment has been widely discussed, but the complex and interrelated scientific and ethical issues remain largely unresolved. This discussion paper, generated by authors who comprised a workgroup of the ICOH Scientific Committee on Rural Health, reviews the use of human experimental studies in regulatory risk assessment for pesticides with a view to advancing the debate as to when, if ever, such studies might be ethically justifiable. The discussion is based on three elements: (a) a review of discussion papers on the topic of human testing of pesticides and the positions adopted by regulatory agencies in developed countries; (b) an analysis of published and unpublished studies involving human testing with pesticides, both in the peer-reviewed literature and in the JMPR database; and (c) application of an ethical analysis to the problem. The paper identifies areas of agreement which include general principles that may provide a starting point on which to base criteria for judgements as to the ethical acceptability of such studies. However, the paper also highlights ongoing unresolved differences of opinion inherent in ethical analysis of contentious issues, which we propose should form a starting point for further debate and the development of guidelines to achieve better resolution of this matter. PMID:20718963

Functions of the cask maintenance facility: A white paper

International Nuclear Information System (INIS)

1987-01-01

The shipping cask systems are the mobile components of the transportation system, designed to safely transport spent nuclear fuel between different facilities under both normal and accident conditions. The cask system will consist of the heavily shielded cask, the cask transport vehicle (truck trailer or railcar), and any associated ancillary equipment (covers, impact limiters, lifting devices, etc.). The cask and certain parts of the cask system must be operated within the limits imposed by a certificate of compliance (COC) granted by the Nuclear Regulatory Commission (NRC). Each cask system must transport spent fuel safely during the life of the system. To maintain the operational effectiveness and safety of the cask systems, a cask maintenance facility (CMF) will be included as an integral part of the transportation system. The planning activity of the transportation system and the design effort of the CMF require that the functions to be performed by the CMF be explicitly defined. The purpose of this paper is to (1) define the potential transportation system functions to be performed at the CMF; (2) examine the impact of this functional definition on the overall transportation system; (3) identify any unresolved issues concerning the interaction of the CMF with other elements of the transportation system; and (4) make recommendations to resolve any unresolved issues so that decisions can be made early in the transportation system planning process

Authors of the Mind

Directory of Open Access Journals (Sweden)

Marcus Dahl

2016-03-01

Full Text Available The article is a brief examination of certain issues affecting the allocation of authorship in early modern plays. Such things as spelling variation, transmission and editorial intervention by hands other than the named ‘author’ could potentially alter the text in ways which are undetectable, thus leaving authorship studies with a number of unresolvable issues as regards its relationship to objective verification.

Thermal reactor safety

International Nuclear Information System (INIS)

1980-06-01

Information is presented concerning new trends in licensing; seismic considerations and system structural behavior; TMI-2 risk assessment and thermal hydraulics; statistical assessment of potential accidents and verification of computational methods; issues with respect to improved safety; human factors in nuclear power plant operation; diagnostics and activities in support of recovery; LOCA transient analysis; unresolved safety issues and other safety considerations; and fission product transport

Thermal reactor safety

Energy Technology Data Exchange (ETDEWEB)

1980-06-01

Information is presented concerning new trends in licensing; seismic considerations and system structural behavior; TMI-2 risk assessment and thermal hydraulics; statistical assessment of potential accidents and verification of computational methods; issues with respect to improved safety; human factors in nuclear power plant operation; diagnostics and activities in support of recovery; LOCA transient analysis; unresolved safety issues and other safety considerations; and fission product transport.

New insight into the unresolved HPLC broad peak of Cabernet Sauvignon grape seed polymeric tannins by combining CPC and Q-ToF approaches.

Science.gov (United States)

Ma, Wen; Waffo-Téguo, Pierre; Alessandra Paissoni, Maria; Jourdes, Michäel; Teissedre, Pierre-Louis

2018-05-30

Polymeric tannins from grapes have always been reported as an unresolved broad peak in HPLC chromatograms, and this has severely limited their identification to date. This study aimed to disassemble this broad peak and explore the polymeric tannin molecules inside. By applying centrifugal partition chromatography (CPC), an efficient separation approach was developed to split the broad peak of grape seed tannins into fractions. Then, the fractions were analyzed by Q-ToF (quadrupole time-of-flight mass spectrometry) to determine the corresponding structures of the tannins. The results suggest that grape seed polymeric tannins were eluted consecutively according to their degree of polymerization (DP). Condensed tannins identified in wine grape seed have a range of DP and degree of galloylation (DG) up to 20 and 11, respectively. The molecular mass of the largest molecule detected was 6067. To our knowledge, this is the first report to offer an insight into the broad peak of polymeric tannins found with HPLC and to characterize the tannins with a DP up to 20 as shown by HRMS and MS/MS data. Copyright © 2018 Elsevier Ltd. All rights reserved.

IJIMAI Editors Note - Vol. 4 Issue 3

Directory of Open Access Journals (Sweden)

Vicente García-Díaz

2017-03-01

This Special Issue tries to show some of the latest researches related to IoT with special emphasis on the basic components of IoT, some of the major applications in which researchers and practitioners are working and especially in aspects related to security, one of the main areas of research related to IoT, with a special emphasis on cloud-based systems. Next, I present a summary of the works that are included in this special issue.

Climate change – a critical emerging issue

CSIR Research Space (South Africa)

Archer van Garderen, Emma RM

2010-01-01

Full Text Available amount of what are termed 'greenhouse gases', including carbon dioxide (CO2) (the best known); but also water vapour and methane (amongst others). Without the presence of greenhouse gases in the atmosphere, the planet would be unable to sustain life... critical emerging issue 1 Climate Change ? a critical emerging issue 1. Introduction We inhabit a dynamic and changing planet, and a changing climate is, clearly, nothing new. In fact, the earth has undergone significant climatic change...

Can the EVIDEM Framework Tackle Issues Raised by Evaluating Treatments for Rare Diseases: Analysis of Issues and Policies, and Context-Specific Adaptation.

Science.gov (United States)

Wagner, Monika; Khoury, Hanane; Willet, Jacob; Rindress, Donna; Goetghebeur, Mireille

2016-03-01

The multiplicity of issues, including uncertainty and ethical dilemmas, and policies involved in appraising interventions for rare diseases suggests that multicriteria decision analysis (MCDA) based on a holistic definition of value is uniquely suited for this purpose. The objective of this study was to analyze and further develop a comprehensive MCDA framework (EVIDEM) to address rare disease issues and policies, while maintaining its applicability across disease areas. Specific issues and policies for rare diseases were identified through literature review. Ethical and methodological foundations of the EVIDEM framework v3.0 were systematically analyzed from the perspective of these issues, and policies and modifications of the framework were performed accordingly to ensure their integration. Analysis showed that the framework integrates ethical dilemmas and issues inherent to appraising interventions for rare diseases but required further integration of specific aspects. Modification thus included the addition of subcriteria to further differentiate disease severity, disease-specific treatment outcomes, and economic consequences of interventions for rare diseases. Scoring scales were further developed to include negative scales for all comparative criteria. A methodology was established to incorporate context-specific population priorities and policies, such as those for rare diseases, into the quantitative part of the framework. This design allows making more explicit trade-offs between competing ethical positions of fairness (prioritization of those who are worst off), the goal of benefiting as many people as possible, the imperative to help, and wise use of knowledge and resources. It also allows addressing variability in institutional policies regarding prioritization of specific disease areas, in addition to existing uncertainty analysis available from EVIDEM. The adapted framework measures value in its widest sense, while being responsive to rare disease

Issues for the 1990s.

Science.gov (United States)

Weiner, Edith; Brown, Arnold

1986-01-01

Discussed are the issues now emerging that seem likely to dominate thinking, planning, and decision-making in the United States and elsewhere during the next decade. These include campus unrest, China as a world economic force, controlling health-care, birth defects, role of the computer in education, and human language/computer language. (RM)

Current Issues and Distributive Justice.

Science.gov (United States)

Rosal, Lorenca Consuelo

1992-01-01

Provides a lesson plan on the issue of distributive justice, or fairness in the ways things are distributed among individuals and groups. Includes a student reading concerning a proposed guaranteed standard of living. Proposes an activity that calls for student discussion of a constitutional amendment that would offer such a guarantee. (SG)

Classroom Implementation. Issues in Assessment.

Science.gov (United States)

Malinowski, Patricia A., Ed.

This booklet, second in a series on issues in assessment, seeks to describe an initiative supported by Finger Lakes Community College (New York) to use classroom assessment techniques (CATs) in different academic areas and to present an overview of some assessment approaches that have been used in the classroom. Papers include: (1) "Enhancing…

Special Issue on Creativity at Work.

Science.gov (United States)

Donnelly, Brian; And Others

1994-01-01

Special issue includes "Creativity at the Workplace" (Donnelly); "Creativity Revisited" (Iandoli); interviews with 16 people who work in or teach industrial engineering, software, and graphic design; "On Creativity and Schooling" (Coppola, Iandoli); and "End Notes: What I Learned" (Iandoli). (SK)

Turbine Replacement Issue

Science.gov (United States)

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

PENGARUH RIGHT ISSUE TERHADAP KINERJA KEUANGAN PERUSAHAAN

Directory of Open Access Journals (Sweden)

Ibnu Khajar

2010-03-01

Full Text Available Penelitian ini menyelidiki pengaruh right issue terhadap kinerja keuangan perusahaan yang go public di Bursa Efek Indonesia. Sampel meliputi dua puluh satu perusahaan yang melakukan right issue dari tahun 2003-2006. Variabel penelitian adalah kinerja keuangan yang diukur dengan rasio likuiditas, leverage, profitabilitas, aktivitas, dan rasio pasar. Paired t-test dan uji Wilcoxon digunakan untuk menentukan perbedaan kinerja keuangan sebelum dan sesudah right issue. Dari rasio kinerja likuiditas, leverage, profitabilitas, aktivitas, dan rasio pasar (Rasio Lancar, Hutang Jumlah Untuk Jumlah Aktiva, Net Profit Margin, Asset Turn Over dan Rasio Price Earning pada dua tahun sebelum dan dua tahun setelah right issue, hanya dua rasio-Harga Earning ratio dan Current Ratio secara signifikan berbeda pada sebelum dan sesudah right issue. Kedua rasio ini meningkat secara signifikan. This study investigated the effect of right issue on the financial performance of companies that go public on the Indonesian Stock Exchange. The sample included twenty-one company that does the right issue from the years 2003-2006. Research variable is financial performance as measured by the liquidity ratio, leverage, profitability, activity, and the ratio of the market. Paired t-test and Wilcoxon test used to determine differences in financial performance before and after the rights issue. From the performance ratios of liquidity, leverage, profitability, activity, and the market ratio (Current Ratio, Total Debt To Total Assets, Net Profit Margin, Asset Turn Over and Price Earning Ratio at two years before and two years after the right issue, only two ratio--Price Earning Ratio and Current Ratio are significantly different at the before and after the rights issue. Both these ratios increased significantly.

Technical issues in licensing low-level radioactive waste facilities

Energy Technology Data Exchange (ETDEWEB)

Junkert, R. [California Dept. of Health Services, CA (United States)

1993-03-01

The California Department of Health Service spent two years in the review of an application for a low-level radioactive waste disposal facility in California. During this review period a variety of technical issues had to be evaluated and resolved. One of the first issues was the applicability and use of NRC guidance documents for the development of LLW disposal facilities. Other technical issues that required intensive evaluations included surface water hydrology, seismic investigation, field and numerical analysis of the unsaturated zone, including a water infiltration test. Source term verification became an issue because of one specific isotope that comprised more than 90% of the curies projected for disposal during the operational period. The use of trench liners and the proposed monitoring of the unsaturated zone were reviewed by a highly select panel of experts to provide guidance on the need for liners and to ensure that the monitoring system was capable of monitoring sufficient representative areas for radionuclides in the soil, soil gas, and soil moisture. Finally, concerns about the quality of the preoperational environmental monitoring program, including data, sample collection procedures, laboratory analysis, data review and interpretation and duration of monitoring caused a significant delay in completing the licensing review.

Research projects lead by the USDA Cranberry Entomology Laboratory (CEL)

Science.gov (United States)

1. Newly discovered native nematode species represent bio-insecticides (grad student project) a. Problems being addressed: Issues over flea beetle control; unresolved questions over pesticide use during bloom. b. Discoveries: at least two native nematodes species new to science have been discovered ...

Merits and challenges of career adaptability as a tool towards sustainable careers

NARCIS (Netherlands)

Buyken, M.B.W.; Klehe, U.-C.; Zikic, J.; van Vianen, A.E.M.; de Vos, A.; van der Heijden, B.I.J.M.

2015-01-01

The chapter discusses how career adaptability can be valuable in constructing sustainable careers. Still, the concept faces a number of challenges and unresolved issues. First, we address the conceptualization of career adaptability as a composite construct and argue in particular that the component

Consensus strategies for the nonoperative management of patients with blunt splenic injury: A Delphi study

NARCIS (Netherlands)

Olthof, Dominique C.; van der Vlies, Cornelius H.; Joosse, Pieter; van Delden, Otto M.; Jurkovich, Gregory J.; Goslings, J. C.; Angle, J. F.; Chakraverty, S.; Coimbra, R.; Demetriades, D.; Denys, A.; Duchesne, J. C.; Fabian, T. C.; Feliciano, D. V.; Fingerhut, A.; Gaarder, C.; Haan, J. M.; Hanks, S. E.; Hauser, C. J.; Heuer, M.; Hoffer, E. K.; Hoyt, D. B.; Ivatury, R. R.; Jurkovich, G. J.; Leenen, L. P.; Leppaniemi, A.; Maegele, M.; Michel, L. A.; Moore, E. E.; Peitzman, A. B.; Reekers, J. A.; Scalea, T. M.; Velmahos, G. C.; de Waele, J. J.; Wisner, D. H.

2013-01-01

BACKGROUND: Nonoperative management is the standard of care in hemodynamically stable patients with blunt splenic injury. However, a number of issues regarding the management of these patients are still unresolved. The aim of this study was to reach consensus among experts concerning optimal

A research view of supply chain management: Developments and ...

African Journals Online (AJOL)

SCM) since its inception in the early-1980s. However, there are still some basic issues of SCM that remain unresolved. Much of the research that has been conducted takes one or more of the following three perspectives: (1) development of ...

Axon Guidance of Sympathetic Neurons to Cardiomyocytes by Glial Cell Line-Derived Neurotrophic Factor (GDNF)

NARCIS (Netherlands)

Miwa, Keiko; Lee, Jong-Kook; Takagishi, Yoshiko; Opthof, Tobias; Fu, Xianming; Hirabayashi, Masumi; Watabe, Kazuhiko; Jimbo, Yasuhiko; Kodama, Itsuo; Komuro, Issei

2013-01-01

Molecular signaling of cardiac autonomic innervation is an unresolved issue. Here, we show that glial cell line-derived neurotrophic factor (GDNF) promotes cardiac sympathetic innervation in vitro and in vivo. In vitro, ventricular myocytes (VMs) and sympathetic neurons (SNs) isolated from neonatal

Social Media Channels in Health Care Research and Rising Ethical Issues.

Science.gov (United States)

Azer, Samy A

2017-11-01

Social media channels such as Twitter, Facebook, and LinkedIn have been used as tools in health care research, opening new horizons for research on health-related topics (e.g., the use of mobile social networking in weight loss programs). While there have been efforts to develop ethical guidelines for internet-related research, researchers still face unresolved ethical challenges. This article investigates some of the risks inherent in social media research and discusses how researchers should handle challenges related to confidentiality, privacy, and consent when social media tools are used in health-related research. © 2017 American Medical Association. All Rights Reserved.

Unresolved theoretical problems

International Nuclear Information System (INIS)

Vogt, E.

1983-03-01

A summary is given of nuclear physics ideas which form the perspective within which the spin excitations in nuclei should be considered. Past work on the nuclear shell model, nuclear collective motion, cluster degrees of freedom and isobaric analogic resonances is reviewed. Indications of the future directions physicists should be taking are discussed. The importance of joining quantum chromodynamics with study of atomic nuclei, and in particular the GT resonance, is highlighted

Supply chain strategies, issues and models

CERN Document Server

Ramanathan, Ramakrishnan

2014-01-01

In the 21st century, supply chain operations and relationships among supply chain partners have become highly challenging, necessitating new approaches, e.g., the development of new models. Supply Chain Strategies, Issues and Models discusses supply chain issues and models with examples from actual industrial cases. Expert authors with a wide spectrum of knowledge working in various areas of supply chain management from various geographical locations offer refreshing, novel and insightful ideas and address possible solutions using established theories and models. Supply Chain Strategies, Issues and Models features studies that have used mathematical modeling, statistical analyses and also descriptive qualitative studies. The chapters cover many relevant themes related to supply chains and logistics including supply chain complexity, information sharing, quality (six sigma), electronic Kanbans, inventory models, scheduling, purchasing and contracts. To facilitate easy reading, the chapters that deal with suppl...

Cultural and Gender Issues in Long-Duration Flights

Science.gov (United States)

1997-01-01

Session TA5 includes short reports concerning: (1) Psychological Issues During Long-Duration International Space Missions; (2) Psychosocial Issues in Crew Selection: Finding the Right Mix of the Right Stuff; (3) Culture, Gender and Mission Accomplishment: Operational Experience; (4) Interpersonal Tension in Multicultural Crews; (5) Personality and Coping in Extreme Environments; and (6) Application of Expedition and Polar Work Group Findings for Enhancing Performance in Space.

Topical issues in nuclear, radiation and radioactive waste safety. Contributed papers

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-08-01

The IAEA International Conference on Topical Issues in Nuclear, Radiation and Radioactive Waste Safety was held in Vienna, Austria, 30 August - 4 September 1998 with the objective to foster the exchange of information on topical issues in nuclear, radiation and radioactive waste safety, with the aim of consolidating an international consensus on: the present status of these issues; priorities for future work; and needs for strengthening international co-operation, including recommendations for the IAEA`s future activities. The document includes 43 papers presented at the Conference dealing with the following topical issues: Safety Management; Backfitting, Upgrading and Modernization of NPPs; Regulatory Strategies; Occupational Radiation Protection: Trends and Developments; Situations of Chronic Exposure to Residual Radioactive Materials: Decommissioning and Rehabilitation and Reclamation of Land; Radiation Safety in the Far Future: The Issue of Long Term Waste Disposal. A separate abstract and indexing were provided for each paper. Refs, figs, tabs

Topical issues in nuclear, radiation and radioactive waste safety. Contributed papers

International Nuclear Information System (INIS)

1998-08-01

The IAEA International Conference on Topical Issues in Nuclear, Radiation and Radioactive Waste Safety was held in Vienna, Austria, 30 August - 4 September 1998 with the objective to foster the exchange of information on topical issues in nuclear, radiation and radioactive waste safety, with the aim of consolidating an international consensus on: the present status of these issues; priorities for future work; and needs for strengthening international co-operation, including recommendations for the IAEA's future activities. The document includes 43 papers presented at the Conference dealing with the following topical issues: Safety Management; Backfitting, Upgrading and Modernization of NPPs; Regulatory Strategies; Occupational Radiation Protection: Trends and Developments; Situations of Chronic Exposure to Residual Radioactive Materials: Decommissioning and Rehabilitation and Reclamation of Land; Radiation Safety in the Far Future: The Issue of Long Term Waste Disposal. A separate abstract and indexing were provided for each paper

New Brunswick Market Design Committee : Congestion management issues

International Nuclear Information System (INIS)

2001-01-01

The restructuring of the New Brunswick wholesale power market comprises a number of issues that need to be resolved concerning transmission system related policy decisions and detailed design issues. The wholesale market structure, ownership structure, and means of preventing market power abuses all have an impact on the resolution of many of those issues. Some transmission related decisions regarding congestion management must be made, and they are examined in this document. The report includes a discussion of the issues related to congestion on the transmission system, a review of the decisions that remain to be made while proposing a number of alternatives, reviews decisions that other jurisdictions have made in somewhat similar circumstances. Finally, the advantages and disadvantages of each alternative are identified. Several high level transmission tariff design issues requiring to be addressed later in greater detail are listed in this document. 1 tab

Confronting uncomfortable truths: receptivity and resistance to Aboriginal content in midwifery education.

Science.gov (United States)

Thackrah, Rosalie D; Thompson, Sandra C

2013-12-01

The emotional responses of students undertaking a new, compulsory unit on Indigenous cultures and health were investigated as part of a broader study looking at culturally secure practice in midwifery education and service provision for Aboriginal women. Classroom observations were conducted on a first year midwifery cohort from July to October 2012 and students completed 'before and after' questionnaires. A spectrum of emotional responses was identified and found to be consistent with studies of medical student exposure to Aboriginal content. While stereotypes were challenged and perceptions altered as a result of the content, issues surrounding racism remained unresolved, with some students expressing dismay at the attitudes of their peers. This study confirmed the need for content on Aboriginal health and cultures to extend beyond one unit in a course. Learning and knowledge must be carefully integrated and developed to maximise understanding and ensure that unresolved issues are addressed.

Psychosocial issues in long-term space flight: overview

Science.gov (United States)

Palinkas, L. A.

2001-01-01

Anecdotal evidence of the individual and interpersonal problems that occurred during the Shuttle-Mir Space Program (SMSP) and other long-duration Russian/Soviet missions, and studies of personnel in other isolated and confined extreme (ICE) environments suggest that psychosocial elements of behavior and performance are likely to have a significant impact on the outcome of long-duration missions in space. This impact may range from individual decrements in performance, health and well being, to catastrophic mission failure. This paper reviews our current understanding of the psychosocial issues related to long duration space missions according to three different domains of behavior: the individual domain, the interpersonal domain and the organizational domain. Individual issues include: personality characteristics that predict successful performance, stress due to isolation and confinement and its effect on emotions and cognitive performance, adaptive and maladaptive coping styles and strategies, and requirements for the psychological support of astronauts and their families during the mission. Interpersonal issues include: impact of crew diversity and leadership styles on small group dynamics, adaptive and maladaptive features of ground-crew interactions, and processes of crew cohesion, tension and conflict. Organizational issues include: the influence of organizational culture and mission duration on individual and group performance, and managerial requirements for long duration missions. Improved screening and selection of astronaut candidates, leadership, coping and interpersonal skills training of personnel, and organizational change are key elements in the prevention of performance decrements on long-duration missions.

Addressing Transgender Issues in Schools

Science.gov (United States)

Cavanagh, Marian

2016-01-01

As mainstream media focus more attention on transgender issues, and as anti-discrimination laws evolve, a shift is taking place on campuses. Many schools now include gender identity and expression in their inclusivity work and seek to establish policies and procedures to support transgender students and their families. It's not an easy task. In…

Introducing to the first issue

Directory of Open Access Journals (Sweden)

Cesar Acleto

2014-06-01

Full Text Available The presentation of the first issue of the REVISTA PERUANA DE BIOLOGíA, as official organ of dissemination of ASOCIACION DE BIOLOGOS DE LA UNIVERSIDAD DE SAN MARCOS, the reverse of the COVER is included with editorial information and BACK COVER with guidelines for authors and the reverse table with the CONTENS.

Estimating the environmental costs of electricity: an overview and review of the issues

International Nuclear Information System (INIS)

Freeman, A.M. III

1996-01-01

This paper provides an overview of the issues associated with environmental costing and the specific questions raised by the effort to measure the environmental costs of electricity. It focuses on three sets of issues. The first set is several conceptual issues in the valuation of environmental impacts in general. These issues are not unique to valuing the environmental impacts of electricity generation. However each of these issues has been highlighted in one way or another by the studies being discussed here. The second set of issues are specific to the design of studies of environmental effects of generating electricity. These issues are the selection of externalities for inclusion in the analysis, and whether and to what extent to include so called upstream and downstream impacts. The third set of issues involves policy implications of the results of the work that has been done to date. Factors considered include health effects of air emissions, damage to ecosystems, damage by CO 2 . 31 refs

Ca2+ signaling in taste bud cells and spontaneous preference for fat: unresolved roles of CD36 and GPR120.

Science.gov (United States)

Abdoul-Azize, Souleymane; Selvakumar, Subramaniam; Sadou, Hassimi; Besnard, Philippe; Khan, Naim Akhtar

2014-01-01

Recent compelling evidences from rodent and human studies raise the possibility for an additional sixth taste modality devoted to oro-gustatory perception of dietary lipids. Understanding the mechanisms underlying oro-gustatory detection of dietary fat is critical for the prevention and treatment of obesity. A number of studies have suggested that lingual CD36, a glycoprotein, highly expressed by circumvallate papillae of the tongue, is implicated in the perception of dietary fat taste. G protein-coupled receptors (GPCRs) are important signaling molecules for many aspects of cellular functions. It has been shown that these receptors, particularly GPR120, are also involved in lipid taste perception. We have shown that dietary long-chain fatty acids (LCFAs), in CD36-positive taste bud cells (TBC), induce increases in free intracellular Ca(2+) concentrations, [Ca(2+)]i, by recruiting Ca(2+) from endoplasmic reticulum (ER) pool via inositol 1,4,5-triphosphate production, followed by Ca(2+) influx via opening of store-operated Ca(2+) (SOC) channels. GPR120 is also coupled to increases in [Ca(2+)]i by dietary fatty acids. We observed that stromal interaction molecule 1 (STIM1), a sensor of Ca(2+) depletion in the ER, mediated fatty acid-induced Ca(2+) signaling and spontaneous preference for fat in the mouse. In this review article, we discuss the recent advances and unresolved roles of CD36 and GPR120 in lipid taste signaling in taste bud cells. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Ethical issues across different fields of forensic science.

Science.gov (United States)

Yadav, Praveen Kumar

2017-01-01

Many commentators have acknowledged the fact that the usual courtroom maxim to "tell the truth, the whole truth, and nothing but the truth" is not so easy to apply in practicality. In any given situation, what does the whole truth include? In case, the whole truth includes all the possible alternatives for a given situation, what should a forensic expert witness do when an important question is not asked by the prosecutor? Does the obligation to tell the whole truth mean that all possible, all probable, all reasonably probable, all highly probable, or only the most probable alternatives must be given in response to a question? In this paper, an attempt has been made to review the various ethical issues in different fields of forensic science, forensic psychology, and forensic DNA databases. Some of the ethical issues are common to all fields whereas some are field specific. These ethical issues are mandatory for ensuring high levels of reliability and credibility of forensic scientists.

Data management issues in mobile ad hoc networks.

Science.gov (United States)

Hara, Takahiro

2017-01-01

Research on mobile ad hoc networks (MANETs) has become a hot research topic since the middle 1990's. Over the first decade, most research focused on networking techniques, ignoring data management issues. We, however, realized early the importance of data management in MANETs, and have been conducting studies in this area for 15 years. In this review, we summarize some key technical issues related to data management in MANETs, and the studies we have done in addressing these issues, which include placement of data replicas, update management, and query processing with security management. The techniques proposed in our studies have been designed with deep considerations of MANET features including network partitioning, node participation/disappearance, limited network bandwidth, and energy efficiency. Our studies published in early 2000's have developed a new research field as data management in MANETs. Also, our recent studies are expected to be significant guidelines of new research directions. We conclude the review by discussing some future directions for research.

About vectors

CERN Document Server

Hoffmann, Banesh

1975-01-01

From his unusual beginning in ""Defining a vector"" to his final comments on ""What then is a vector?"" author Banesh Hoffmann has written a book that is provocative and unconventional. In his emphasis on the unresolved issue of defining a vector, Hoffmann mixes pure and applied mathematics without using calculus. The result is a treatment that can serve as a supplement and corrective to textbooks, as well as collateral reading in all courses that deal with vectors. Major topics include vectors and the parallelogram law; algebraic notation and basic ideas; vector algebra; scalars and scalar p

Steam generator operating experience update, 1982-1983

International Nuclear Information System (INIS)

Frank, L.

1984-06-01

This report is a continuation of earlier reports by the staff addressing pressurized water reactor steam generator operating experience. NUREG-0886, Steam Generator Tube Experience, published in February 1982 summarized experience in domestic and foreign plants through December 1981. This report summarizes steam generator operating experience in domestic plants for the years 1982 and 1983. Included are new problems encountered with secondary-side loose parts, sulfur-induced stress-assisted corrosion cracking, and flow-induced vibrational wear in the new preheater design steam generators. The status of Unresolved Safety Issues A3, A4, and A5 is also discussed

The money issue.

Science.gov (United States)

Carpenter, Dave; Haugh, Richard

2003-06-01

Volume is rising at a healthy pact. Technology is improving patient care. Many organizations have, out of necessity, strengthened business fundamentals, controlled costs and refined their focus. Yet not-for-profit hospitals are squeezed by a cash crunch that has balance sheets under pressure and credit downgrades outpacing upgrades--the result of shrinking investment income, rising pension obligations, low government reimbursement and other threats to operational stability. N&HN looks at the challenges, including recent fallout from the most pressing issues, how some systems have responded, and the pros and cons of borrowing now.

Mobility in Higher Education: Cross-Cultural Communication Issues.

Science.gov (United States)

Baumgratz, Gisela

1993-01-01

A study of the role of foreign languages in European higher education focused on the influence of institutional culture, including that of the discipline, on quality of professional communication. Findings are discussed, and related issues are examined, including student/professional mobility, interinstitutional cooperation, standards for…

Ethical and Professional Issues in Computer-Assisted Therapy.

Science.gov (United States)

Ford, B. Douglas

1993-01-01

Discusses ethical and professional issues in psychology regarding computer-assisted therapy (CAT). Topics addressed include an explanation of CAT; whether CAT is psychotherapy; software, including independent use, validation of effectiveness, and restricted access; clinician resistance; client acceptance; the impact on ethical standards; and a…

Ecuador's Presidential Election: Background on Economic Issues

OpenAIRE

Mark Weisbrot; Luis Sandoval; Belén Cadena

2006-01-01

This paper looks at the biggest economic challenges that Ecuador's new president will need to address, and examines its recent economic history, including the issues of growth, dollarization, and international trade and finance.

The language barrier education in Africa: The challenge of learning ...

African Journals Online (AJOL)

The issues relating to language of instruction, mathematical language and interaction with mathematics education have remained unresolved. The interaction between these variables have attracted research understandings in recent years. This paper reports a study of the level of understanding of mathematical terms and ...

Novel concepts for preparation of reference materials as whole water samples for priority substances at nanogram-per-liter level using model suspended particulate matter and humic acids

NARCIS (Netherlands)

Elordui-Zapatarietxe, S.; Fettig, I.; Philipp, R.; Gantois, F.; Lalère, B.; Swart, C.; Petrov, P.; Goenaga-Infante, H.; Vanermen, G.; Boom, G.; Emteborg, H.

2015-01-01

One of the unresolved issues of the European Water Framework Directive is the unavailability of realistic water reference materials for the organic priority pollutants at low nanogram-per-liter concentrations. In the present study, three different types of ready-to-use water test materials were

An astronomically-tuned climate framework for hominins in the Turkana Basin

NARCIS (Netherlands)

Joordens, J.C.A.; Vonhof, H.B.; Feibel, C.S.; Lourens, L.J.; Dupont-Nivet, G.; Lubbe, J.H.J.L. van der; Sier, M.J.; Davies, G.R.; Kroon, D.

2011-01-01

Understanding the influence of orbital climate cycles on hominin evolution remains a key challenge in paleoanthropology. The two major unresolved issues are: the absence of a climate proxy yielding high-resolution (< 20 kyr) terrestrial climate records, and the lack of age control on hominin fossil

Factors related to the high fall rate in long-term care residents with dementia

NARCIS (Netherlands)

Kosse, Nienke M.; de Groot, Maartje H.; Vuillerme, Nicolas; Hortobagyi, Tibor; Lamoth, Claudine J. C.

Background: Falls in long-term care residents with dementia represent a costly but unresolved safety issue. The aim of the present study was to (1) determine the incidence of falls, fall-related injuries and fall circumstances, and (2) identify the relationship between patient characteristics and

Critical notes on microbiological risk assessment of food

NARCIS (Netherlands)

Reij, M.W.; Schothorst, van M.

2000-01-01

Although numerous papers on Microbiological Risk Assessment (MRA) of food products have been published, a number of issues related to it remain unresolved. This paper explains the role of Microbiological Risk Assessment in the context of Risk Analysis as outlined by Codex Alimentarius. It reviews

Facilitation between bovids and equids on an African savanna

NARCIS (Netherlands)

Odadi, W.O.; Jain, M.; Wieren, van S.E.; Prins, H.H.T.; Rubenstein, D.I.

2011-01-01

Background: Equids, especially zebras and donkeys, and cattle (bovids) share habitats in many savanna ecosystems in Africa. The issue of competition for food between these ungulate guilds remains largely unresolved. Resolving it will provide insights into how wild zebra are likely to interact with

Microbes are trophic analogues of arthropods, mammals, and fish: Isotopic fingerprinting unites ‘green’ and ‘brown’ food webs

Science.gov (United States)

This work addresses a cross-cutting issue within the field of food-web ecology—the integration of the microbiome into trophic hierarchies. The nature and degree to which microbes may reconfigure the trophic identities of carnivore and omnivore groups have remained surprisingly unresolved. This means...

Regional Economic Integration and the Governance Challenge in ...

African Journals Online (AJOL)

There exists a growing consensus among scholars and observers that critical issues on governance and development in Africa, which have remained unresolved, continue to pose obstacles to Africa's economic integration efforts. Although the continent has witnessed different stages in the evolution of regional economic ...

The patient who believes and the analyst who does not (1).

Science.gov (United States)

Lijtmaer, Ruth M

2009-01-01

A patient's religious beliefs and practices challenge the clinical experience and self-knowledge of the analyst owing to a great complexity of factors, and often take the form of the analyst's resistances and countertransference reactions to spiritual and religious issues. The analyst's feelings about the patient's encounters with religion and other forms of healing experiences may result in impasses and communication breakdown for a variety of reasons. These reasons include the analyst's own unresolved issues around her role as a psychoanalyst-which incorporates in some way psychoanalysis's views of religious belief-and these old conflicts may be irritated by the religious themes expressed by the patient. Vignettes from the treatments of two patients provide examples of the analyst's countertransference conflicts, particularly envy in the case of a therapist who is an atheist.

Potential effects of gallium on cladding materials

International Nuclear Information System (INIS)

Wilson, D.F.; Beahm, E.C.; Besmann, T.M.; DeVan, J.H.; DiStefano, J.R.; Gat, U.; Greene, S.R.; Rittenhouse, P.L.; Worley, B.A.

1997-10-01

This paper identifies and examines issues concerning the incorporation of gallium in weapons derived plutonium in light water reactor (LWR) MOX fuels. Particular attention is given to the more likely effects of the gallium on the behavior of the cladding material. The chemistry of weapons grade (WG) MOX, including possible consequences of gallium within plutonium agglomerates, was assessed. Based on the calculated oxidation potentials of MOX fuel, the effect that gallium may have on reactions involving fission products and possible impact on cladding performance were postulated. Gallium transport mechanisms are discussed. With an understanding of oxidation potentials and assumptions of mechanisms for gallium transport, possible effects of gallium on corrosion of cladding were evaluated. Potential and unresolved issues and suggested research and development (R and D) required to provide missing information are presented

Mathematical and physical theory of turbulence

CERN Document Server

Cannon, John

2006-01-01

Although the current dynamical system approach offers several important insights into the turbulence problem, issues still remain that present challenges to conventional methodologies and concepts. These challenges call for the advancement and application of new physical concepts, mathematical modeling, and analysis techniques. Bringing together experts from physics, applied mathematics, and engineering, Mathematical and Physical Theory of Turbulence discusses recent progress and some of the major unresolved issues in two- and three-dimensional turbulence as well as scalar compressible turbulence. Containing introductory overviews as well as more specialized sections, this book examines a variety of turbulence-related topics. The authors concentrate on theory, experiments, computational, and mathematical aspects of Navier-Stokes turbulence; geophysical flows; modeling; laboratory experiments; and compressible/magnetohydrodynamic effects. The topics discussed in these areas include finite-time singularities a...

Steam generator issues in the United States

International Nuclear Information System (INIS)

Strosnider, J.R.

1997-01-01

Alloy 600 steam generator tubes in the US have exhibited degradation mechanisms similar to those observed in other countries. Effective programs have been implemented to address several degradation mechanisms including: wastage; mechanical wear; pitting; and fatigue. These degradation mechanisms are fairly well understood as indicated by the ability to effectively mitigate/manage them. Stress corrosion cracking (SCC) is the dominant degradation mechanism in the US. SCC poses significant inspection and management challenges to the industry and the regulators. The paper also addresses issues of research into SCC, inspection programs, plugging, repair strategies, water chemistry, and regulatory control. Emerging issues in the US include: parent tube cracking at sleeve joints; detection and repair of circumferential cracks; free span cracking; inspection and cracking of dented regions; and severe accident analysis

Ethical issues with colorectal cancer screening-a systematic review.

Science.gov (United States)

Hofmann, Bjørn

2017-06-01

Colorectal cancer (CRC) screening is widely recommended and implemented. However, sometimes CRC screening is not implemented despite good evidence, and some types of CRC screening are implemented despite lack of evidence. The objective of this article is to expose and elucidate relevant ethical issues in the literature on CRC screening that are important for open and transparent deliberation on CRC screening. An axiological question-based method is used for exposing and elucidating ethical issues relevant in HTA. A literature search in MEDLINE, Embase, PsycINFO, PubMed Bioethics subset, ISI Web of Knowledge, Bioethics Literature Database (BELIT), Ethics in Medicine (ETHMED), SIBIL Base dati di bioetica, LEWI Bibliographic Database on Ethics in the Sciences and Humanities, and EUROETHICS identified 870 references of which 114 were found relevant according to title and abstract. The content of the included papers were subject to ethical analysis to highlight the ethical issues, concerns, and arguments. A wide range of important ethical issues were identified. The main benefits are reduced relative CRC mortality rate, and potentially incidence rate, but there is no evidence of reduced absolute mortality rate. Potential harms are bleeding, perforation, false test results, overdetection, overdiagnosis, overtreatment (including unnecessary removal of polyps), and (rarely) death. Other important issues are related to autonomy and informed choice equity, justice, medicalization, and expanding disease. A series of important ethical issues have been identified and need to be addressed in open and transparent deliberation on CRC screening. © 2016 John Wiley & Sons, Ltd.

Resolution of Generic Safety Issue 29: Bolting degradation or failure in nuclear power plants

International Nuclear Information System (INIS)

Johnson, R.E.

1990-06-01

This report describes the US Nuclear Regulatory Commission's (NRC's) Generic Safety Issue 29, ''Bolting Degradation or Failure in Nuclear Power Plants,'' including the bases for establishing the issue and its historical highlights. The report also describes the activities of the Atomic Industrial Forum (AIF) relevant to this issue, including its cooperation with the Materials Properties Council (MPC) to organize a task group to help resolve the issue. The Electric Power Research Institute, supported by the AIF/MPC task group, prepared and issued a two-volume document that provides, in part, the technical basis for resolving Generic Safety Issue 29. This report presents the NRC's review and evaluation of the two-volume document and NRC's conclusion that this document, in conjunction with other information from both industry and NRC, provides the bases for resolving this issue

Problems and prospects for nuclear waste disposal policy

International Nuclear Information System (INIS)

Herzik, E.B.; Mushkatel, A.H.

1996-01-01

This book is a collection of articles examining legal, organizational, and public-interest issues involving the transportation, storage, treatment, and disposal of radioactive wastes. The introductions examines the unresolved issues of nuclear-waste policy-making in the USA and then presents essays covering the disposal of commercial power plant fuel, low level radioactive wastes, the by-products of nuclear weapons production, and the challenges of transporting radiological materials

Security For Wireless Sensor Network

OpenAIRE

Saurabh Singh,; Dr. Harsh Kumar Verma

2011-01-01

Wireless sensor network is highly vulnerable to attacks because it consists of various resourceconstrained devices with their low battery power, less memory, and associated low energy. Sensor nodescommunicate among themselves via wireless links. However, there are still a lot of unresolved issues in wireless sensor networks of which security is one of the hottest research issues. Sensor networks aredeployed in hostile environments. Environmental conditions along with resource-constraints give...

77 FR 38631 - Request for Comments on Ethical Issues Associated with the Development of Medical Countermeasures...

Science.gov (United States)

2012-06-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Request for Comments on Ethical Issues Associated with the... ethical issues associated with the development of medical countermeasures for children, including ethical... issues associated with the development of medical countermeasures for children, including ethical...

Public Policy Issues on the Horizon.

Science.gov (United States)

Business Officer, 1997

1997-01-01

The National Association of College and University Business Officers (NACUBO) has identified public policy issues of interest to its membership in 1997, including those in budget and appropriations, college costs and pricing, distance learning and technology, environmental health and safety, federal audit and accounting standards, Higher Education…

Electronic Publishing: Introduction to This Issue.

Science.gov (United States)

Siegel, Martin A.

1994-01-01

Provides an overview of this special issue that addresses the possibilities and implications of electronic publishing and information dissemination as key components of effective education. Highlights include the theory and framework of electronic publishing; differences between electronic text and print; development of new educational materials;…

Issues in midterm analysis and forecasting 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

Issues in Midterm Analysis and Forecasting 1998 (Issues) presents a series of nine papers covering topics in analysis and modeling that underlie the Annual Energy Outlook 1998 (AEO98), as well as other significant issues in midterm energy markets. AEO98, DOE/EIA-0383(98), published in December 1997, presents national forecasts of energy production, demand, imports, and prices through the year 2020 for five cases -- a reference case and four additional cases that assume higher and lower economic growth and higher and lower world oil prices than in the reference case. The forecasts were prepared by the Energy Information Administration (EIA), using EIA`s National Energy Modeling System (NEMS). The papers included in Issues describe underlying analyses for the projections in AEO98 and the forthcoming Annual Energy Outlook 1999 and for other products of EIA`s Office of Integrated Analysis and Forecasting. Their purpose is to provide public access to analytical work done in preparation for the midterm projections and other unpublished analyses. Specific topics were chosen for their relevance to current energy issues or to highlight modeling activities in NEMS. 59 figs., 44 tabs.

Issues in protection of human subjects in internet research.

Science.gov (United States)

Im, Eun-Ok; Chee, Wonshik

2002-01-01

Despite the increasing use of the Internet among nurses, the use of the Internet in nursing research has been rarely discussed and critiqued in terms of issues in protection of human subjects. In this article, issues in protection of human subjects in Internet research are explored by analyzing an Internet study to propose directions for human protection in Internet research. Issues raised through the study include those related to (a) anonymity and confidentiality, (b) security, (c) self-determination and authenticity, (d) full disclosure, and (e) fair treatment. Based on discussion of the five issues, development of standardized guidelines, investigator triangulation, and information sharing are proposed as directions for protection of human subjects in Internet research.

Perspectives and reconciliation of viewpoints on risk assessment issues

International Nuclear Information System (INIS)

Smith, C.F.; Cohen, J.J.

1980-01-01

It is important to recognize the distinction between risk assessment and its components which include risk analysis, perspectives study, and decision analysis. Divergence of opinion within the scientific community as well as the public at large is a characteristic of issues related to nuclear power. The divergent opinions can largely be characterized as either optimistic or pessimistic in nature. Reconciliation of divergent viewpoints presents some difficult challenges. It is doubtful that issues which have an emotional or philosophical basis can be resolved through technical efforts. Public education on the technical issues might prove helpful

Chronical Illness and the Issue of Context in Dietary Counselling

DEFF Research Database (Denmark)

Kristensen, Søren Tange

food and eating issues are taken into account in dietary counselling and how this reflects broader epistemological and political issues related to the prevention and management of chronic illness. A concluding statement from the study is that in order to empower clients, the complexity and contextual......In dietary counselling contextual food and eating issues are increasingly considered important when trying to promote dietary change. Besides transferring knowledge on healthy eating based on an assessment of the nutritional adequacy of clients diet priority is given to obtain the full dietary...... story including contextual issues concerning relationships, family values, culture, finances, and personal beliefs. The focus on contextual issues seems to reflect a holistic and empowering approach to the promotion of health. Also, the consideration of contextual issues can be seen as essential...

A review of ethical issues in dementia.

Science.gov (United States)

Johnson, Rebecca A; Karlawish, Jason

2015-10-01

Dementia raises many ethical issues. The present review, taking note of the fact that the stages of dementia raise distinct ethical issues, focuses on three issues associated with stages of dementia's progression: (1) how the emergence of preclinical and asymptomatic but at-risk categories for dementia creates complex questions about preventive measures, risk disclosure, and protection from stigma and discrimination; (2) how despite efforts at dementia prevention, important research continues to investigate ways to alleviate clinical dementia's symptoms, and requires additional human subjects protections to ethically enroll persons with dementia; and (3) how in spite of research and prevention efforts, persons continue to need to live with dementia. This review highlights two major themes. First is how expanding the boundaries of dementias such as Alzheimer's to include asymptomatic but at-risk persons generate new ethical questions. One promising way to address these questions is to take an integrated approach to dementia ethics, which can include incorporating ethics-related data collection into the design of a dementia research study itself. Second is the interdisciplinary nature of ethical questions related to dementia, from health policy questions about insurance coverage for long-term care to political questions about voting, driving, and other civic rights and privileges to economic questions about balancing an employer's right to a safe and productive workforce with an employee's rights to avoid discrimination on the basis of their dementia risk. The review highlights these themes and emerging ethical issues in dementia.

XFEL OSCILLATOR SIMULATION INCLUDING ANGLE-DEPENDENT CRYSTAL REFLECTIVITY

International Nuclear Information System (INIS)

Fawley, William; Lindberg, Ryan; Kim, K.-J.; Shvyd'ko, Yuri

2010-01-01

The oscillator package within the GINGER FEL simulation code has now been extended to include angle-dependent reflectivity properties of Bragg crystals. Previously, the package was modified to include frequencydependent reflectivity in order to model x-ray FEL oscillators from start-up from shot noise through to saturation. We present a summary of the algorithms used for modeling the crystal reflectivity and radiation propagation outside the undulator, discussing various numerical issues relevant to the domain of high Fresnel number and efficient Hankel transforms. We give some sample XFEL-O simulation results obtained with the angle-dependent reflectivity model, with particular attention directed to the longitudinal and transverse coherence of the radiation output.

Nursing students' experiences of ethical issues in clinical practice: A New Zealand study.

Science.gov (United States)

Sinclair, J; Papps, E; Marshall, B

2016-03-01

Nursing students experience ethical problems in clinical practice in a different way from registered nurses. In order to develop ethical reasoning and competence in nursing students, nurse educators must recognise the unique issues students face. This research described the occurrence of ethical issues in clinical practice for 373 undergraduate nursing students who responded to a national questionnaire investigating the frequency of pre-determined ethical issues and the corresponding level of distress. Over two thirds of respondents experienced breaches of a patient's right to confidentiality, privacy, dignity or respect and 87% experienced unsafe working conditions. The most distressing issues were those that compromised patient safety, including unsafe healthcare practices, working conditions and suspected abuse or neglect. Themes that emerged from an open-ended question included lack of support and supervision, bullying and end of life issues. This research found the frequency at which ethical issues are experienced was highest in year three participants. However, the overall distress levels were lower for the majority of issues for those participants in the later part of their degree. Recommendations from this research include developing ethics education around the main concerns that students face in order to enhance students' understanding, resilience and ability to respond appropriately. Copyright © 2016 Elsevier Ltd. All rights reserved.

NST Quarterly - issue October 2001

International Nuclear Information System (INIS)

2001-01-01

NST Quarterly reports current development in Nuclear Science and Technology in Malaysia. In this issue it reviews GM technology and GMOs - genetically modified organisms. The topics discussed includes the implication of GM in practice, the controversy and the prospect of GM technology. Radioactive pig - something like a ball or plug which cleanses the inner walls of the pipeline, also briefly presented

Legal issues relating to the Ontario FIT contract - An update

International Nuclear Information System (INIS)

Weizman, Michael

2011-01-01

The paper discusses the legal issues related to the Ontario FIT contract, which includes the FIT waiver agreement, WTO challenge, FIT extension, political risk assessment and issues related to unforeseen events beyond human control (force majeure). The risk of termination of the FIT waiver is omitted for convenience by OPA but timing implications relating to the FIT waiver are included. The binding agreement for supply of generating equipment is also presented and the term sheet for turbine equipment and bill of purchase being understood as binding agreements is questioned. Political risks relate to existing contracts, lawsuit risks and changes to the REA process. Change in government and the implications of minority government can be added to the political risks. A successful WTO challenge has been assumed and the possible implications are discussed. Some of them include risk to FIT contracts already issued; changes in DC requirements and in FIT contract pricing and re-pricing of construction and turbine equipment supply contracts if DC requirements are relaxed.

Organization, activities, and issues with particular emphasis on coal

International Nuclear Information System (INIS)

Cole, D.R.

1992-01-01

The paper discusses Colorado's coal industry; the Colorado Mining Association; lobbying and legislative actions; industry networking, information, and communications; coal issues and activities; and Colorado issues and activities. Some of the latter include: land reclamation of mined lands; oil and gas drilling and coal mine conflicts; wild and scenic river designations; general permitting of coal mining discharges; and coal mine land reclamation awards

Fusion Canada issue 13

International Nuclear Information System (INIS)

1991-01-01

A short bulletin from the National Fusion Program. Included in this issue is a report on Canada's plans to participate in the Engineering Design Activities (EDA), bilateral meetings with Canada and the U.S., committee meeting with Canada-Europe, an update at Tokamak de Varennes on Plasma Biasing experiments and boronized graphite tests, fusion materials research at the University of Toronto using a dual beam accelerator and a review of the CFFTP and the CCFM. 2 figs

EFRT M-12 Issue Resolution: Solids Washing

Energy Technology Data Exchange (ETDEWEB)

Baldwin, David L.; Schonewill, Philip P.; Toth, James J.; Huckaby, James L.; Eslinger, Paul W.; Hanson, Brady D.; Kurath, Dean E.; Minette, Michael J.

2010-01-01

Pacific Northwest National Laboratory (PNNL) was tasked by Bechtel National Inc. (BNI) on the River Protection Project-Hanford Tank Waste Treatment and Immobilization Plant (RPP-WTP) project to perform research and development activities to resolve technical issues identified for the Pretreatment Facility (PTF). The Pretreatment Engineering Platform (PEP) was designed, constructed, and operated as part of a plan to respond to issue M12, “Undemonstrated Leaching Processes” of the External Flowsheet Review Team (EFRT) issue response plan.( ) The PEP is a 1/4.5-scale test platform designed to simulate the WTP pretreatment caustic leaching, oxidative leaching, ultrafiltration solids concentration, and slurry washing processes. The PEP replicates the WTP leaching processes using prototypic equipment and control strategies. The PEP also includes non-prototypic ancillary equipment to support the core processing.

Evaluation on safety issues of SMART

International Nuclear Information System (INIS)

Kim, W. S.; Seol, K. W.; Yoon, Y. K.; Lee, J. H.

2001-01-01

Safety issues on the SMART were evaluated in the light of the compliance with the Ministerial Ordinance of Technical Requirements applying to Nuclear Installations, which was recently revised. Evaluation concludes that regulatory requirements associated with following items have to be developed as the licensing criteria for the SMART: (1) proving the safety of design or materials different form existing reactors; (2) coping with beyond design basis accidents; (3) rulemaking on the safety of reactor safeguard vessel ; (4) ensuring integrity of steam generator tubes; and (5) classifying equipment based on their safety significance. Appropriate actions including implementation of new requirements under development should be taken for safety issues such as diversity of reactivity control and in-service inspection of steam generator tubes that are not complied with the current Technical Requirements. Safety level of the SMART design will be evaluated further by the more detailed assessment according to the Technical Requirements, and additional safety issues will be identified and resolved, if it necessary

Cyber security issues in online games

Science.gov (United States)

Zhao, Chen

2018-04-01

With the rapid development of the Internet, online gaming has become a way of entertainment for many young people in the modern era. However, in recent years, cyber security issues in online games have emerged in an endless stream, which have also caused great attention of many game operators. Common cyber security problems in the game include information disclosure and cyber-attacks. These problems will directly or indirectly cause economic losses to gamers. Many gaming companies are enhancing the stability and security of their network or gaming systems in order to enhance the gaming user experience. This article has carried out the research of the cyber security issues in online games by introducing the background and some common cyber security threats, and by proposing the latent solution. Finally, it speculates the future research direction of the cyber security issues of online games in the hope of providing feasible solution and useful information for game operators.

Advances in molecular-based diagnostics in meeting crop biosecurity and phytosanitary issues.

Science.gov (United States)

Schaad, Norman W; Frederick, Reid D; Shaw, Joe; Schneider, William L; Hickson, Robert; Petrillo, Michael D; Luster, Douglas G

2003-01-01

Awareness of crop biosecurity and phytosanitation has been heightened since 9/11 and the unresolved anthrax releases in October 2001. Crops are highly vulnerable to accidental or deliberate introductions of crop pathogens from outside U.S. borders. Strategic thinking about protection against deliberate or accidental release of a plant pathogen is an urgent priority. Rapid detection will be the key to success. This review summarizes recent progress in the development of rapid real-time PCR protocols and evaluates their effectiveness in a proposed nationwide network of diagnostic laboratories that will facilitate rapid diagnostics and improved communication.

'In situ simulation' versus 'off site simulation' in obstetric emergencies and their effect on knowledge, safety attitudes, team performance, stress, and motivation

DEFF Research Database (Denmark)

Sørensen, Jette Led; Van der Vleuten, Cees; Lindschou, Jane

2013-01-01

learner outcomes. However, many questions on how SBME can be optimized remain unanswered. One unresolved issue is how 'in situ simulation' (ISS) versus 'off site simulation' (OSS) impact learning. ISS means simulation-based training in the actual patient care unit (in other words, the labor room...