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Sample records for unit evaluation form

  1. Patterns in Nature Forming Patterns in Minds: An Evaluation of an Introductory Physics Unit

    Science.gov (United States)

    Sheaffer, Christopher Ryan

    Educators are increasingly focused on the process over the content. In science especially, teachers want students to understand the nature of science and investigation. The emergence of scientific inquiry and engineering design teaching methods have led to the development of new teaching and evaluation methods that concentrate on steps in a process rather than facts in a topic. Research supports the notion that an explicit focus on the scientific process can lead to student science knowledge gains. In response to new research and standards many teachers have been developing teaching methods that seem to work well in their classrooms, but lack the time and resources to test them in other classroom environments. A high school Physics teacher (Bradford Hill) has developed a unit called Patterns in Nature (PIN) with objectives relating mathematical modeling to the scientific process. Designed for use in his large public school classroom, the unit was taken and used in a charter school with small classes. This study looks at specifically whether or not the PIN unit effectively teaches students how to graph the data they gather and fit an appropriate mathematical pattern, using that model to predict future measurements. Additionally, the study looks at the students' knowledge and views about the nature of science and the process of scientific investigation as it is affected by the PIN unit. Findings show that students are able to identify and apply patterns to data, but have difficulties explaining the meaning of the math. Students' show increases in their knowledge of the process of science, and the majority develop positive views about science in general. A major goal of this study is to place this unit in the cyclical process of Design-Based Research and allow for Pattern in Nature's continuous improvement, development and evaluation. Design-Based Research (DBR) is an approach that can be applied to the implementation and evaluation of classroom materials. This method

  2. Careers (A Course of Study). Unit V: Forms, Forms, Forms.

    Science.gov (United States)

    Turley, Kay

    Designed to enable special needs students to understand and complete various job-related forms, this set of activities devoted to forms encountered before and after one obtains a job is the fifth in a nine-unit secondary level careers course intended to provide handicapped students with the knowledge and tools necessary to succeed in the world of…

  3. [PIC Program Evaluation Forms.

    Science.gov (United States)

    Short, N. J.

    These 4 questionnaires are designed to elicit teacher and parent evaluations of the Prescriptive Instruction Center (PIC) program. Included are Teacher Evaluation of Program Effectiveness (14 items), M & M Evaluation of Program Implementation (methods and materials specialists; 11 items), Teacher Evaluation of Program Effectiveness--Case Study…

  4. In vitro and in vivo evaluation of single-unit commercial conventional tablet and sustained-release capsules compared with multiple-unit polystyrene microparticle dosage forms of Ibuprofen.

    Science.gov (United States)

    Tamilvanan, Shunmugaperumal; Sa, Biswanath

    2006-09-01

    The major aims of the present study were (1) to select a multiple-unit formulation that matched the in vitro dissolution profile of single-unit sustained-release commercial capsules, (2) to compare the sustaining/controlling efficacy of the selected multiple-unit formulation with that of the single-unit commercial conventional tablet and sustained-release capsules, and (3) to determine whether an in vitro-in vivo correlation exists for single- and multiple-unit formulations. Ibuprofen (20%-60% wt/wt)-loaded multiple-unit polystyrene microparticles were prepared by an emulsion-solvent evaporation method from an aqueous system. The in vitro release profiles obtained in phosphate buffer of pH 6.8 for drug-loaded polystyrene microparticles and for commercial sustained-release capsules (Fenlong-SR, 400 mg) were compared. Since the microparticles with 30% ibuprofen load showed a release profile comparable to that of the Fenlong-SR release profile, the microparticles with this drug load were considered to be the optimized/selected formulation and, therefore, were subjected to stability study and in vivo study in human volunteers. A single-dose oral bioavailability study revealed significant differences in C(max), T(max), t(1/2a), t(1/2e), K(a), K(e), and AUC between the conventional tablet and optimized or Fenlong-SR capsule dosage forms. However, all the parameters, with the exception of K(a) along with relative bioavailability (F) and retard quotient (R(Delta)), obtained from the optimized ibuprofen-loaded microparticles were lower than that obtained from the commercial Fenlong-SR formulation. Furthermore, linear relationship obtained between the percentages dissolved and absorbed suggests a means to predict in vivo absorption by measuring in vitro dissolution.

  5. Terrestrial Ecosystems - Land Surface Forms of the Conterminous United States

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The U.S. Geological Survey (USGS) has generated land surface form classes for the contiguous United States. These land surface form classes were created as part of...

  6. In vitro and in vivo evaluation of single-unit commercial conventional tablet and sustained-release capsules compared with multiple-unit polystyrene microparticle dosage forms of ibuprofen

    OpenAIRE

    Tamilvanan, Shunmugaperumal; Sa, Biswanath

    2006-01-01

    The major aims of the present study were (1) to select a multiple-unit formulation that matched the in vitro dissolution profile of single-unit sustained-release commercial capsules, (2) to compare the sustaining/controlling efficacy of the selected multiple-unit formulation with that of the single-unit commercial conventional tablet and sustained-release capsules, and (3) to determine whether an in vitro-in vivo correlation exists for single- and multiple-unit formulations. Ibuprofen (20%–60...

  7. Classes of land-surface form in the United States

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This digital dataset describes classes of land-surface form in the conterminous United States. The source of the data is the map of land-surface form in the 1970...

  8. Mobile based optical form evaluation system

    Directory of Open Access Journals (Sweden)

    Asım Sinan YÜKSEL

    2016-05-01

    Full Text Available Optical forms that contain multiple-choice answers are widely used both for electing students and evaluating student achievements in education systems in our country and worldwide. Optical forms are evaluated by employing optical mark recognition techniques through optical readers. High cost of these machines, limited access to them, long waiting time for evaluation results make the process hard for educationists working in cities or countries. In this study, a mobile application was developed for the educationists who own mobile phones or tablets for the purpose of evaluating students' answer sheets quickly and independent of location and optical readers. Optical form recognition, reading and evaluation processes are done on the image of student's answer sheet that is taken with the mobile phone or tablet of educationist. The Android based mobile application that we developed has a user-friendly interface, high success rate and is the first of our knowledge application that operates on mobile platforms in this field.

  9. A simple and fast method for determining colony forming units

    NARCIS (Netherlands)

    Sieuwerts, S.; Bok, de F.A.M.; Mols, E.; Vos, de W.M.; Hylckama Vlieg, van J.E.T.

    2008-01-01

    Aims: To develop a flexible and fast colony forming unit quantification method that can be operated in a standard microbiology laboratory. Methods and Results: A miniaturized plating method is reported where droplets of bacterial cultures are spotted on agar plates. Subsequently, minicolony spots ar

  10. Fast free-form deformation using graphics processing units.

    Science.gov (United States)

    Modat, Marc; Ridgway, Gerard R; Taylor, Zeike A; Lehmann, Manja; Barnes, Josephine; Hawkes, David J; Fox, Nick C; Ourselin, Sébastien

    2010-06-01

    A large number of algorithms have been developed to perform non-rigid registration and it is a tool commonly used in medical image analysis. The free-form deformation algorithm is a well-established technique, but is extremely time consuming. In this paper we present a parallel-friendly formulation of the algorithm suitable for graphics processing unit execution. Using our approach we perform registration of T1-weighted MR images in less than 1 min and show the same level of accuracy as a classical serial implementation when performing segmentation propagation. This technology could be of significant utility in time-critical applications such as image-guided interventions, or in the processing of large data sets. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

  11. Evaluation of control strategies in forming processes

    Directory of Open Access Journals (Sweden)

    Calmano Stefan

    2015-01-01

    Full Text Available Products of forming processes are subject to quality fluctuations due to uncertainty in semi-finished part properties as well as process conditions and environment. An approach to cope with these uncertainties is the implementation of a closed-loop control taking into account the actual product properties measured by sensors or estimated by a mathematical process model. Both methods of uncertainty control trade off with a financial effort. In case of sensor integration the effort is the cost of the sensor including signal processing as well as the design and manufacturing effort for integration. In case of an estimation model the effort is mainly determined by the time and knowledge needed to derive the model, identify the parameters and implement the model into the PLC. The risk of mismatch between model and reality as well as the risk of wrong parameter identification can be assumed as additional uncertainty (model uncertainty. This paper evaluates controlled and additional uncertainty by taking into account process boundary conditions like the degree of fluctuations in semi-finished part properties. The proposed evaluation is demonstrated by the analysis of exemplary processes.

  12. Organizational evaluation of an interprofessional study unit

    DEFF Research Database (Denmark)

    Jensen, Didde Cramer; Nørgaard, Birgitte; Draborg, Eva;

    2012-01-01

    This article presents results from an organizational evaluation of an interprofessional clinical study unit (ICS) in Denmark. The aim of this study was to test whether the ICS was based on a durable organizational concept and to identify the prerequisites for the unit to be successful....... The evaluation framework was "theory-based evaluation". A program theory was developed based on the concepts and expectations of the steering committee which initiated and designed the ICS. The program theory was tested for conflicts of interest among the stakeholders related to the ICS regarding prerequisites...

  13. Evaluation of new indomethacin dosage forms.

    Science.gov (United States)

    Waller, E S

    1983-01-01

    Indomethacin, an indole derivative nonsteroidal anti-inflammatory drug, has been available since the early 1960s in gelatin capsules. In 1982, a sustained release product, Indocin SR, was marketed. Awaiting marketing approval is a unique controlled release form of indomethacin, Indos. The disposition of indomethacin includes enterohepatic cycling and extensive metabolism to inactive metabolites. Enterohepatic cycling makes interpretation of bioavailability estimates of indomethacin dosage forms difficult. The relationship of indomethacin plasma concentration to therapeutic effects and side effects is inconclusive. It appears in vivo prostaglandin inhibition occurs at very low plasma concentrations that are achievable with all available dosage forms. Indocin SR is a sustained release capsule of indomethacin designed to deliver 25 mg of drug immediately and 50 mg gradually. Absolute bioavailability of the product is 80%. The plasma concentration-time curves do not show good sustained release characteristics; after four hours plasma concentrations resemble those seen with a single dose of regular capsule. The cost compared with Indocin is competitive. Indos is a zero-order release form of indomethacin. It is a unique drug delivery system that shows good controlled release characteristics. Bioavailability is 85%. Both Indocin SR and Indos are apparently therapeutically equivalent to indomethacin capsules. In elderly patients, Indos has been shown to be associated with fewer side effects than Indocin. Both Indocin SR and Indos have the advantage of once or twice daily dosing.

  14. Human Resource Evaluation in Hotel Units

    Directory of Open Access Journals (Sweden)

    George Aspridis

    2012-03-01

    Full Text Available This paper aims at presenting and analysing the performance appraisalsystems and the human potential development in hotelunits. It aims at integrating and updating many aspects of performanceappraisal while concentrating on the hotel units systemto prove the importance of human resource evaluation in hotelunits and the procedure that is to be followed by the enterprisefor further development of hotel employees. HR evaluation analysisis presented through relevant theoretical background on theevaluation method and the presentation of the practical problematicalissues in order to create an image for a whole evaluationsystem of HR in Greek hotel enterprises.

  15. A short form of the neonatal intensive care unit family needs inventory

    Directory of Open Access Journals (Sweden)

    Elisabete Alves

    2016-02-01

    Full Text Available ABSTRACT OBJECTIVE: The identification of parental needs in Neonatal Intensive Care Units is essential to design and implement family-centered care. This article aims to validate the Neonatal Intensive Care Units Family Needs Inventory for the Portuguese population, and to propose a Short Form. METHODS: A linguistic adaptation of the Neonatal Intensive Care Units Family Needs Inventory, a self-report scale with 56-items, was performed. The instrument was administered to 211 parents of infants hospitalized in all level III Neonatal Intensive Care Units in the North of Portugal, 15-22 days after admission (July of 2013-June of 2014. The number of items needed to achieve reliability close to 0.8 was calculated using by the Spearman-Brown formula. The global goodness of fit of the scale was evaluated using the comparative fit index. Construct validity was assessed through association of each dimension score with socio-demographic and obstetric characteristics. RESULTS: Exploratory factor analysis revealed two dimensions, one focused on parents' needs and another on the infant's needs. To compose the Short Form Inventory, items with ceiling effect were eliminated and 22 items were submitted to confirmatory analysis, which supported the existence of two dimensions (CFI = 0.925. The Short Form showed a high degree of reliability (alpha ≥ 0.76. Less educated and older parents more frequently attributed a significantly higher importance to parent-centered needs, while parents of multiples revealed a tendency to value infant-centered needs. CONCLUSIONS: The Short Form of the Neonatal Intensive Care Units Family Needs Inventory is a brief, simple, and valid instrument with a high degree of reliability. Further studies are needed to explore associations with practices of family-centered care.

  16. Effect of bionic coupling units' forms on wear resistance of gray cast iron under dry linear reciprocating sliding condition

    Science.gov (United States)

    Pang, Zuobo; Zhou, Hong; Xie, Guofeng; Cong, Dalong; Meng, Chao; Ren, Luquan

    2015-07-01

    In order to get close to the wear form of guide rails, the homemade linear reciprocating wear testing machine was used for the wear test. In order to improve the wear-resistance of gray cast iron guide rail, bionic coupling units of different forms were manufactured by a laser. Wear behavior of gray-cast-iron with bionic-coupling units has been studied under dry sliding condition at room temperature using the wear testing machine. The wear resistance was evaluated by means of weight loss measurement and wear morphology. The results indicated that bionic coupling unit could improve the wear resistance of gray cast iron. The wear resistance of gray cast iron with reticulation bionic coupling unit is the best. When the load and speed changed, reticulation bionic coupling unit still has excellent performance in improving the wear resistance of gray cast iron.

  17. Evaluation and selection of candidate high-level waste forms

    Energy Technology Data Exchange (ETDEWEB)

    Bernadzikowski, T. A.; Allender, J. S.; Butler, J. L.; Gordon, D. E.; Gould, Jr., T. H.; Stone, J. A.

    1982-03-01

    Seven candidate waste forms being developed under the direction of the Department of Energy's National High-Level Waste (HLW) Technology Program, were evaluated as potential media for the immobilization and geologic disposal of high-level nuclear wastes. The evaluation combined preliminary waste form evaluations conducted at DOE defense waste-sites and independent laboratories, peer review assessments, a product performance evaluation, and a processability analysis. Based on the combined results of these four inputs, two of the seven forms, borosilicate glass and a titanate based ceramic, SYNROC, were selected as the reference and alternative forms for continued development and evaluation in the National HLW Program. Both the glass and ceramic forms are viable candidates for use at each of the DOE defense waste-sites; they are also potential candidates for immobilization of commercial reprocessing wastes. This report describes the waste form screening process, and discusses each of the four major inputs considered in the selection of the two forms.

  18. Cerebral vascular accident: some characteristics of occupational therapy evaluation forms.

    Science.gov (United States)

    Ottenbacher, K

    1980-04-01

    To determine areas most commonly evaluated by occupational therapists and to ascertain methods in which evaluative information is gathered, 35 evaluation forms currently employed by occupational therapists to assess dysfunction in patients with cerebral vascular accident were collected. Five general areas including motor function, sensory deficit, hadn function, activities of daily living, and visual perception were found to be most frequently listed on the forms. These areas were divided into sub areas to operationally define the information collected. Analysis revealed that the level of measurement most frequently employed by therapists to record evaluate findings was the descriptive level. There was a tendency to collect data at "higher" or more sophisticated levels of measurement in those areas evaluated most frequently. The findings are discussed in relation to professional competency concerns and the need to develop unique occupational therapy evaluative instruments for areas of practice such as cerebral vascular accident.

  19. Analytical evaluation of atomic form factors: application to Rayleigh scattering

    CERN Document Server

    Safari, L; Amaro, P; Jänkälä, K; Fratini, F

    2014-01-01

    Atomic form factors are widely used for the characterization of targets and specimens, from crystallography to biology. By using recent mathematical results, here we derive an analytical expression for the atomic form factor within the independent particle model constructed from nonrelativistic screened hydrogenic wavefunctions. The range of validity of this analytical expression is checked by comparing the analytically obtained form factors with the ones obtained within the Hartee-Fock method. As an example, we apply our analytical expression for the atomic form factor to evaluate the differential cross section for Rayleigh scattering off neutral atoms.

  20. Review of the Educational Software Evaluation Forms and Scales

    Directory of Open Access Journals (Sweden)

    Ahmet ARSLAN

    2016-12-01

    Full Text Available The main purpose of this study is to review existing evaluation forms and scales that have been prepared for educational software evaluation. In addition to this purpose, the study aims to provide insight and guidance for future studies in this context. In total, forty-two studies that including evaluation forms and scales have been taken into consideration. “Educational software evaluation”, “Software evaluation”, “Educational software evaluation forms/scales” were searched as keywords in the: “Education Resources Information Centre (ERIC”, “Marmara University e-Library”, “National Thesis Center” and “Science Direct” databases. Twenty-nine of them have met the review selection criteria and been evaluated. There is an increase in the number of evaluation tools between 2006 – 2010. However, it was noticed that there is no sufficient number of evaluation tools targeting “educational games”. It was concluded that reliability and validity studies are very important part of developing educational software evaluation tools and this is a matter that should be considered in future studies.

  1. Cross-platform digital assessment forms for evaluating surgical skills

    Directory of Open Access Journals (Sweden)

    Steven Arild Wuyts Andersen

    2015-04-01

    Full Text Available A variety of structured assessment tools for use in surgical training have been reported, but extant assessment tools often employ paper-based rating forms. Digital assessment forms for evaluating surgical skills could potentially offer advantages over paper-based forms, especially in complex assessment situations. In this paper, we report on the development of cross-platform digital assessment forms for use with multiple raters in order to facilitate the automatic processing of surgical skills assessments that include structured ratings. The FileMaker 13 platform was used to create a database containing the digital assessment forms, because this software has cross-platform functionality on both desktop computers and handheld devices. The database is hosted online, and the rating forms can therefore also be accessed through most modern web browsers. Cross-platform digital assessment forms were developed for the rating of surgical skills. The database platform used in this study was reasonably priced, intuitive for the user, and flexible. The forms have been provided online as free downloads that may serve as the basis for further development or as inspiration for future efforts. In conclusion, digital assessment forms can be used for the structured rating of surgical skills and have the potential to be especially useful in complex assessment situations with multiple raters, repeated assessments in various times and locations, and situations requiring substantial subsequent data processing or complex score calculations.

  2. Cross-platform digital assessment forms for evaluating surgical skills.

    Science.gov (United States)

    Andersen, Steven Arild Wuyts

    2015-01-01

    A variety of structured assessment tools for use in surgical training have been reported, but extant assessment tools often employ paper-based rating forms. Digital assessment forms for evaluating surgical skills could potentially offer advantages over paper-based forms, especially in complex assessment situations. In this paper, we report on the development of cross-platform digital assessment forms for use with multiple raters in order to facilitate the automatic processing of surgical skills assessments that include structured ratings. The FileMaker 13 platform was used to create a database containing the digital assessment forms, because this software has cross-platform functionality on both desktop computers and handheld devices. The database is hosted online, and the rating forms can therefore also be accessed through most modern web browsers. Cross-platform digital assessment forms were developed for the rating of surgical skills. The database platform used in this study was reasonably priced, intuitive for the user, and flexible. The forms have been provided online as free downloads that may serve as the basis for further development or as inspiration for future efforts. In conclusion, digital assessment forms can be used for the structured rating of surgical skills and have the potential to be especially useful in complex assessment situations with multiple raters, repeated assessments in various times and locations, and situations requiring substantial subsequent data processing or complex score calculations.

  3. Redox Biology Course Evaluation Form | Center for Cancer Research

    Science.gov (United States)

    To improve the Redox Biology (RB) course in future years, we would appreciate your feedback by completing this course evaluation. Please score the course elements as poor, fair, average, good or excellent. Please type any comments that you have in response to the questions at the bottom of the form. Remember to include your name as you wish it to appear on the certificate. Thank you for your feedback.

  4. Evaluating pharmaceutical waste disposal in pediatric units.

    Science.gov (United States)

    Almeida, Maria Angélica Randoli de; Wilson, Ana Maria Miranda Martins; Peterlini, Maria Angélica Sorgini

    2016-01-01

    To verify the disposal of pharmaceutical waste performed in pediatric units. A descriptive and observational study conducted in a university hospital. The convenience sample consisted of pharmaceuticals discarded during the study period. Handling and disposal during preparation and administration were observed. Data collection took place at pre-established times and was performed using a pre-validated instrument. 356 drugs disposals were identified (35.1% in the clinic, 31.8% in the intensive care unit, 23.8% in the surgical unit and 9.3% in the infectious diseases unit). The most discarded pharmacological classes were: 22.7% antimicrobials, 14.8% electrolytes, 14.6% analgesics/pain killers, 9.5% diuretics and 6.7% antiulcer agents. The most used means for disposal were: sharps' disposable box with a yellow bag (30.8%), sink drain (28.9%), sharps' box with orange bag (14.3%), and infectious waste/bin with a white bag (10.1%). No disposal was identified after drug administration. A discussion of measures that can contribute to reducing (healthcare) waste volume with the intention of engaging reflective team performance and proper disposal is necessary. Verificar o descarte dos resíduos de medicamentos realizado em unidades pediátricas. Estudo descritivo e observacional, realizado em um hospital universitário. A amostra de conveniência foi constituída pelos medicamentos descartados durante o período de estudo. Observaram-se a manipulação e o descarte durante o preparo e a administração. A coleta dos dados ocorreu em horários preestabelecidos e realizada por meio de instrumento pré-validado. Identificaram-se 356 descartes de medicamentos (35,1% na clínica, 31,8% na unidade de cuidados intensivos, 23,8% na cirúrgica e 9,3% na infectologia). As classes farmacológicas mais descartadas foram: 22,7% antimicrobianos, 14,8% eletrólitos, 14,6% analgésicos, 9,5% diuréticos e 6,7% antiulcerosos. Vias mais utilizadas: caixa descartável para perfurocortante com

  5. INTELLIGENT SYSTEM TO EVALUATE THE NEIGHBORHOOD UNIT CRITERIA

    Directory of Open Access Journals (Sweden)

    Suha A. Abdulrahman

    2013-05-01

    Full Text Available The modern idea of town planning is to plan it under the hierarchic design of service centers levels begin from neighborhood unit level to residential district. It's done by using indicator numbers and areas, that the urban designer returned to them in the planning .this research aims to recognize the neighborhood units slandered by using the intelligent programs system to evaluated three plans of neighborhood unit designed by the researchers to make them in the right design . 

  6. New Hydrogen Bonded Supramolecular Hydrogels Formed through Gelating Two Isomeric Building Units Simultaneously

    Institute of Scientific and Technical Information of China (English)

    Ji Wei WU; Li Ming TANG; Kai CHEN; Liang YAN; Yu Jiang WANG

    2006-01-01

    New hydrogen bonded supramolecular hydrogels were formed through simultaneously gelating two isomeric building units, 4-oxo-4-(2-pyridinylamino)butanoic acid (G1) and 4-oxo-4-(3-pyridinylamino)butanoic acid (G2) at various molar ratios in water.

  7. 75 FR 39950 - Proposed Collection; Comment Request; Cancer Trials Support Unit (CTSU) Public Use Forms and...

    Science.gov (United States)

    2010-07-13

    ... Unit (CTSU) Public Use Forms and Customer Satisfaction Surveys (NCI) SUMMARY: In compliance with the... and Use of Information Collection: CTSU collects annual surveys of customer satisfaction for clinical...: 2 CTSU Web Site Customer 250 10-15 0.2500 1.00 63 Satisfaction Survey. 3 CTSU Helpdesk Customer 300...

  8. Development, evaluation, and utility of a peer evaluation form for online teaching.

    Science.gov (United States)

    Gaskamp, Carol D; Kintner, Eileen

    2014-01-01

    Formative assessment of teaching by peers is an important component of quality improvement for educators. Teaching portfolios submitted for promotion and tenure are expected to include peer evaluations. Faculty resources designed for peer evaluation of classroom teaching are often inadequate for evaluating online teaching. The authors describe development, evaluation, and utility of a new peer evaluation form for formative assessment of online teaching deemed relevant, sound, feasible, and beneficial.

  9. Effect of Fluoride Mouthrinse and Toothpaste on Number of Streptococcal Colony Forming Units of Dental Plaque

    Directory of Open Access Journals (Sweden)

    SE Jabbarifar

    2005-11-01

    Full Text Available Background: Frequent topical fluoride therapy through toothpaste, mouthrinse, professional gels and solutions causes decrease in incidence, pause and repair of dental caries in the enamel. These mechanisms are done through penetration of fluoride ions (F- and their replacement with hydroxyl ions (OH- of hydroxyappatite of enamel, interfere with microbial metabolism of dental plaque and bacteriostatic effect on some cariogenic bacterial strains such as streptococci. The aim of this study was to examine the effect of fluoride mouthrinse and toothpaste on the number of streptococcal colony forming units of dental plaque. Methods: 62 children with 6-7 years old were put in two groups. Samples of dental plaque from each group were collected both before and after use of the fluoride mouthrinse and or toothpaste. The samples were cultured on blood agar to find the number of streptococcal colony forming units (CFU. The mean colony forming unit was compared inter and intra groups before and after application of Fluoride products. Results: The streptococcal CFU of dental plaque before and after use of the mouthrinse and toothpaste respectively was (1240±1367, 1253±1341.5 and (551±716, 898±1151. Statistically, the streptococcal CFU in each group before and after use of the toothpaste and mouthrinse was significantly different. Conclusion: The findings of this study indicated that the fluoride toothpaste and mouthrinse reduce number of streptococcal colony forming units of dental plaque. Also this reduction was not depended on level of (F- Ions, sort of vehicle of fluoride and frequent application of the fluoride mouthrinse and toothpaste. Keywords: fluoride mouthrinse, fluoride toothpaste, colony forming unit (CFU, streptococcus

  10. A Novel Octanuclear Molecular Loop Formed by Linkage of Oxo-centered Triruthenium Cluster Units

    Institute of Scientific and Technical Information of China (English)

    Jing Lin CHEN; Li Yi ZHANG; Zhong Ning CHEN

    2005-01-01

    A novel dimeric complex [Ru3Ⅲ,Ⅲ,Ⅱ(μ3-O)(μ-CH3COO)(CO)]2(μ-dppf)(μ-odppf) (dppf =1, l′-bis(diphenylphosphio)ferrocene, odppf = 1, 1′-bis(oxodiphenylphosphoranyl)ferrocene) (1) of oxo-centered triruthenium-aectate cluster units was synthesized and characterized by X-ray crystallography. Compound 1 exhibits a cyclic structure formed by linkages of two triruthenium cluster units Ru3Ⅲ,Ⅲ, Ⅱ (μ3-O)(μ-CH3COO)6(CO) through dppf and odppf ligands, respectively. The diameter of the molecular loop is ca. 1.0 nm.

  11. United Parcel Service Evaluates Hybrid Electric Delivery Vans (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2010-02-01

    This fact sheet describes how the National Renewable Energy Laboratory's Fleet Test and Evaluation team evaluated the 12-month, in-service performance of six Class 4 hybrid electric delivery vans - fueled by regular diesel - and six comparable conventional diesel vans operated by the United Parcel Service.

  12. Multibarrier waste forms. Part II. Characterization and evaluation.

    Energy Technology Data Exchange (ETDEWEB)

    Rusin, J.M.; Gray, W.J.; Wald, J.W.

    1979-08-01

    The multibarrier concept for the storage of radioactive waste is to use up to three barriers to isolate radionuclides from the environment: a solidified waste inner core, an impervious coating, and a metal matrix. The four multibarrier waste forms were evaluated for thermal stability (volatility), mechanical strength (impact resistance), and leach resistance. This report discusses the characterization of the multibarrier waste forms and compares them to reference calcine and glass waste forms. The weight loss of supercalcine-ceramics after 4 h in dry air ranges between 0.01 and 1.6 wt % from 1000 to 1200/sup 0/C and is dependent upon composition. Glass marbles in a cast lead alloy offer approximately an order of magnitude decease in the wt % fines < 37 ..mu..m released after impact as compared to a glass monolith. CVD-coated supercalcine in a sintered 410 SS matrix offers up to two orders of magnitude decrease. Hot-pressed supercalcine ceramics may offer no increase in impact resistance or leach resistance over that of a glass monolith. Supercalcine may offer no advantage over waste glasses in leach resistance. Glass and PyC/Al/sub 2/O/sub 3/ coatings provide effective inert leaching barriers.

  13. Evaluating the MBTI® Form M in a South African context

    Directory of Open Access Journals (Sweden)

    Casper J.J. van Zyl

    2012-09-01

    Full Text Available Orientation: Psychological instruments require continued refinement, updating andevaluation.Research purpose: To investigate the reliability, validity and differential item functioning ofthe MBTI® Form M across groups in South Africa using Classical Test Theory (CTT and ItemResponse Theory (IRT methods.Motivation for the study: To add to the continual research and improvement of the MBTI®Form M through the investigation of its psychometric properties across groups in South Africa.Research design, approach and method: This study falls within the quantitative researchparadigm. Classical test theory methods and Rasch analysis were used to evaluate thefunctioning of the MBTI Form M across gender and ethnic groups. A cross-sectional study wascompleted consisting of 10 705 South African respondents.Main findings: Excellent reliability was found for the instrument across groups in thesample. Good evidence for construct validity was found using exploratory factor analysis andconfirmatory factor analysis. Some evidence for uniform bias was found across ethnic andgender groups and a few items reflected non-uniform DIF across gender groups only. Theeffect of uniform and non-uniform DIF did not appear to have major practical implications forthe interpretation of the scales.Practical/managerial implications: The results provided evidence that supports thepsychometric validity of the MBTI instrument in the South African context.Contribution/value-add: This study is the largest study to date regarding the psychometricfunctioning of the MBTI instrument in South Africa. It contributes to the evolution of theinstrument in line

  14. Response of colony-forming units-spleen to heavy charged particles.

    Science.gov (United States)

    Ainsworth, E J; Kelly, L S; Mahlmann, L J; Schooley, J C; Thomas, R H; Howard, J; Alpen, E L

    1983-10-01

    Survival of colony-forming units-spleen (CFU-S) was measured after single doses of photons or heavy charged particles from the BEVALAC. The purposes were to define the radiosensitivity to heavy ions used medically and to evaluate relationships between relative biological effectiveness (RBE) and dose-averaged linear energy transfer (LET infinity). In in vitro irradiation experiments. CFU-S suspensions were exposed to 220 kVp X rays or to 20Ne (372 MeV/micron) or 40Ar (447 MeV/micron) particles in the plateau portion of the Bragg curve. In in vivo irradiation experiments, donor mice from which CFU-S were harvested were exposed to 12C (400 MeV/micron). 20Ne (400 or 670 MeV/micron), or 40Ar (570 MeV/micron) particles in Bragg peaks spread to 4 or 10 cm by spiral ridge filters. Based on RBE at 10 survival, the maximum RBE of 2.1 was observed for 40Ar particles characterized by an LET infinity of approximately 100 keV/micron. Lower RBEs were determined at lower or higher estimated values of LET infinity and ranged from 1.1 for low energy 40Ar particles to 1.5-1.6 for low energy 12C and 20Ne. The responses of CFU-S are compared with responses of other model systems to heavy charged particles and with the reported sensitivity of CFU-S to neutrons of various energies. The maximum RBE reported here, 2.1 for high energy 40Ar particles, is somewhat lower than values reported for fission-spectrum neutrons, and is appreciably lower than values for monoenergetic 0.43-1.8 MeV neutrons. Low energy 12C and 20Ne particles have RBEs in the range of values reported for 14.7 MeV neutrons.

  15. Biocompatibility evaluation of magnetosomes formed by Acidithiobacillus ferrooxidans

    Energy Technology Data Exchange (ETDEWEB)

    Yan Lei [Institute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, 730000 (China); College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, 163319 (China); Yue Xiaoxuan [Institute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, 730000 (China); Zhang Shuang [College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, 163319 (China); Chen Peng [Institute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, 730000 (China); GIBT, Gansu Institute of Business and Technology, Yannan Road 18, Lanzhou, 730010 (China); Xu Zhiliang; Li Yang [Institute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, 730000 (China); Li Hongyu, E-mail: hekouyanlei@gmail.com [Institute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, 730000 (China)

    2012-10-01

    Magnetite nanocrystal has been extensively used in biomedical field. Currently, an interesting alternative to synthetic magnetic Fe{sub 3}O{sub 4} nanoparticles, called magnetosome, has been found in magnetotactic bacteria. It has been reported that Acidithiobacillus ferrooxidans (At. ferrooxidans) has a potential to synthesize magnetosome. In this study, transmission electron microscope (TEM) was used to analyze the magnetite particles in At. ferrooxidans BY-3. The magnetosomes formed by this bacterium were isolated by a method combining ultracentrifugation and magnetic separation. Crystalline phase and surface functional group of the magnetosomes were investigated by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR), respectively. Biocompatibility of the magnetosomes was systematically evaluated at various concentrations (0.5, 1.0, 2.0 and 4.0 mg/ml). MTT test, hemolysis assay and Micronucleus Test were carried out to evaluate in vitro cytotoxicity, blood toxicity and genotoxicity of magnetosomes, respectively. Under these conditions, magnetosomes showed no cytotoxic, genotoxic and hemolytic effects up to 4.0 mg/ml indicating good biocompatibility of these biological nanoparticles. These revealed that the magnetosomes might have a potential for biotechnological and biomedical applications in the future. - Highlights: Black-Right-Pointing-Pointer The production of magnetosomes from At. ferrooxidans has been easily available. Black-Right-Pointing-Pointer Several techniques are used to characterize properties of the magnetosomes. Black-Right-Pointing-Pointer The magnetosomes have no cytotoxicity, no hemolysis activity and no genotoxicity.

  16. Designing usable web forms- Empirical evaluation of web form improvement guidelines

    DEFF Research Database (Denmark)

    Seckler, Mirjam; Heinz, Silvia; Bargas-Avila, Javier A.

    2014-01-01

    This study reports a controlled eye tracking experiment (N = 65) that shows the combined effectiveness of 20 guidelines to improve interactive online forms when applied to forms found on real company websites. Results indicate that improved web forms lead to faster completion times, fewer form su...... submission trials, and fewer eye movements. Data from subjective questionnaires and interviews further show increased user satisfaction. Overall, our findings highlight the importance for web designers to improve their web forms using UX guidelines.......This study reports a controlled eye tracking experiment (N = 65) that shows the combined effectiveness of 20 guidelines to improve interactive online forms when applied to forms found on real company websites. Results indicate that improved web forms lead to faster completion times, fewer form...

  17. Preliminary evaluation of alternative forms for immobilization of Savannah River Plant high-level waste. [Eleven alternative solid forms

    Energy Technology Data Exchange (ETDEWEB)

    Stone, J.A.; Goforth, S.T. Jr.; Smith, P.K.

    1979-12-01

    An evaluation of available information on eleven alternative solid forms for immobilization of SRP high-level waste has been completed. Based on the assessment of both product and process characteristics, four forms were selected for more detailed evaluation: (1) borosilicate glass made in the reference process, (2) a high-silica glass made from a porous glass matrix, (3) crystalline ceramics such as supercalcine or SYNROC, and (4) ceramics coated with an impervious barrier. The assessment includes a discussion of product and process characteristics for each of the eleven forms, a cross comparison of these characteristics for the forms, and the bases for selecting the most promising forms for further study.

  18. Evaluation of seasonal exergy efficiency of air handing unit

    Directory of Open Access Journals (Sweden)

    Kęstutis Genys

    2015-10-01

    Full Text Available The article deals with the air handling unit seasonal exergy efficiency. TRNSYS simulation tool is used to evaluate it. The object of research is air treatment device used to treat an air for the ventilation of laboratory. The mathematical model of air handling unit using TRNSYS simulation tool was developed when the technical parameters of air handling unit and energy exchange in it were analysed. The developed model according to the made observations during the warm and cold periods was tested and validation of elements was performed. The simulation of air handling unit operation after the verification of reliability and permitted tolerances was performed. The control mechanisim which allows simulating the operation of air handling unit during cold and warm periods of the year was made. The mathematical algorithm for calculation of air handling unit exergy efficiency coefficient applying the principles of exergy analysis was developed. The seasonal exergy efficiency of air handling unit equal to 3.94 percent during the simulation was obtained.

  19. Extreme Response Predictions for Jack-up Units in Second Order Stochastic Waves by FORM

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Capul, Julien

    2006-01-01

    An efficient procedure for derivation of mean outcrossing rates for non-linear wave-induced responses in stationary sea states is presented and applied to an analysis of the horizontal deck sway of a jack-up unit. The procedure is based on the theory of random vibrations and uses the first order...... reliability method (FORM) to estimate the most probable set of wave components in the ocean wave system that will lead to exceedance of a specific response level together with the associated mean outcrossing rate. The procedure bears some resemblance to the Constrained NewWave methodology, but is conceptually......-tic waves, not previously included in the analysis of jack-up units in stochastic seaways....

  20. Performance Evaluation of a Modular Detector Unit for X-Ray Computed Tomography

    Directory of Open Access Journals (Sweden)

    Guangshu Hu

    2013-04-01

    Full Text Available A research prototype CT scanner is currently under development in our lab. One of the key components in this project is the CT detector. This paper describes the design and performance evaluation of the modular CT detector unit for our proposed scanner. It consists of a Photodiode Array Assembly which captures irradiating X-ray photons and converts the energy into electrical current, and a mini Data Acquisition System which performs current integration and converts the analog signal into digital samples. The detector unit can be easily tiled together to form a CT detector. Experiments were conducted to characterize the detector performance both at the single unit level and system level. The noise level, linearity and uniformity of the proposed detector unit were reported and initial imaging studies were also presented which demonstrated the potential application of the proposed detector unit in actual CT scanners.

  1. 17 CFR 274.11d - Form N-6, registration statement of separate accounts organized as unit investment trusts that...

    Science.gov (United States)

    2010-04-01

    ... variable life insurance policies. Form N-6 shall be used as the registration statement to be filed pursuant... statement of separate accounts organized as unit investment trusts that offer variable life insurance... insurance policies to register as unit investment trusts. This form shall also be used for...

  2. Comparative evaluation of adverse drug reaction reporting forms for introduction of a spontaneous generic ADR form

    Directory of Open Access Journals (Sweden)

    Anshi Singh

    2012-01-01

    Full Text Available Despite comprehensive and stringent phases of clinical trials and surveillance efforts, unexpected and serious adverse drug reactions (ADRs repeatedly occur after the drug is marketed. ADR reporting is an important aspect of an efficient and effective pharmacovigilance program. Although Medwatch, Yellow Card, CDSCO form, etc. are the protocol forms of ADR collection and reports, a number of countries design and use their respective ADR forms. This review compares similarities and dissimilarities of 13 ADR forms of countries representing their geographical location. This study extracted 73 data elements mentioned in 13 different ADR forms. Only 13 elements were common. An ADR form of Malaysia and Canada covers the highest number of data 43, while Brazil falls to the opposite end with a number of 17 data elements in lieu with the Generic ADR Form. The result of this review highlights 58 data elements of the proposed generic ADR form which ensures that requisite reporting information essential for correct causality assessment of ADRs are included. The proposed "Generic ADR form" could be adopted worldwide mandatorily for reporting any/all ADRs associated with marketed drugs.

  3. Petroleum Refinery Hydrogen Production Unit: Exergy and Production Cost Evaluation

    Directory of Open Access Journals (Sweden)

    Silvio de Oliveira Júnior

    2008-12-01

    Full Text Available Some specific processes are required to obtain pure hydrogen and the most usual one is natural gas reforming, where natural gas reacts with superheated steam producing H2, CO, CO2 and H2O. This paper presents the exergy and production costs evaluation of a complete hydrogen production unit of a petroleum refinery. The hydrogen production unit analysed in this paper has to supply 550,000 Nm3 of hydrogen per day to purify diesel oil. Based on a synthesis plant of the hydrogen production unit, the exergy efficiency of each component and of the overall plant are calculated. The hydrogen production cost is determined by means of a thermoeconomic analysis in which the equality cost partition method is employed, including capital and operational costs, in order to determine the production cost of hydrogen and other products of the plant.

  4. Effectiveness of the United States Marine Corps Tiered Evaluation System

    Science.gov (United States)

    2015-03-01

    effectiveness. 14. SUBJECT TERl’\\IS Tiered Evaluation System, First Tenn Alignment Program, Quality, Retention 15. NUMBER OF PAGES 17. SECURITY...Crider Approved by: Jeremy A. Arkes Thesis Advisor Chad W. Seagren Co-Advisor William Gates Dean, Graduate School of Business...Lastly, first- tenn Marine re-enlistees must possess a high school diploma or altemate credential (Headquatiers, United States Marine C01ps, 2010

  5. Short-Form Philadelphia Naming Test: Rationale and Empirical Evaluation

    Science.gov (United States)

    Walker, Grant M.; Schwartz, Myrna F.

    2012-01-01

    Purpose: To create two matched short forms of the Philadelphia Naming Test (PNT; Roach, Schwartz, Martin, Grewal, & Brecher, 1996) that yield similar results to the PNT for measuring anomia. Method: In Study 1, archived naming data from 94 individuals with aphasia were used to identify which PNT items should be included in the short forms. The 2…

  6. Cross-platform digital assessment forms for evaluating surgical skills

    DEFF Research Database (Denmark)

    Andersen, Steven Arild Wuyts

    2015-01-01

    containing the digital assessment forms, because this software has cross-platform functionality on both desktop computers and handheld devices. The database is hosted online, and the rating forms can therefore also be accessed through most modern web browsers. Cross-platform digital assessment forms were...... developed for the rating of surgical skills. The database platform used in this study was reasonably priced, intuitive for the user, and flexible. The forms have been provided online as free downloads that may serve as the basis for further development or as inspiration for future efforts. In conclusion...... assessment situations. In this paper, we report on the development of cross-platform digital assessment forms for use with multiple raters in order to facilitate the automatic processing of surgical skills assessments that include structured ratings. The FileMaker 13 platform was used to create a database...

  7. Objective evaluation of oral presentation skills using Inertial Measurement Units.

    Science.gov (United States)

    Sessa, Salvatore; Kong, Weisheng; Zhang, Di; Cosentino, Sarah; Manawadu, Udara; Kawasaki, Motoji; Thomas, George Thuruthel; Suzuki, Tomohiro; Tsumura, Ryosuke; Takanishi, Atsuo

    2015-01-01

    Oral presentation is considered as one of the most sought after skills by companies and professional organizations and program accreditation agencies. However, both learning process and evaluation of this skill are time demanding and complex tasks that need dedication and experience. Furthermore, the role of the instructor is fundamental during the presentation assessment. The instructor needs to consider several verbal and nonverbal communications cues sent in parallel and this kind of evaluation is often subjective. Even if there are oral presentation rubrics that try to standardize the evaluation, they are not an optimal solution because they do not provide the presenter a real-time feedback. In this paper, we describe a system for behavioral monitoring during presentations. We propose an ecological measurement system based on Inertial Measurement Units to evaluate objectively the presenter's posture through objective parameters. The system can be used to provide a real-time feedback to the presenters unobtrusively.

  8. The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat.

    Science.gov (United States)

    Suzuki, Hiroshi; Ito, Yasuyuki; Yamazaki, Yuji; Mineta, Katsuhiko; Uji, Masami; Abe, Kazuhiro; Tani, Kazutoshi; Fujiyoshi, Yoshinori; Tsukita, Sachiko

    2013-01-01

    Euglenoid flagellates have striped surface structures comprising pellicles, which allow the cell shape to vary from rigid to flexible during the characteristic movement of the flagellates. In Euglena gracilis, the pellicular strip membranes are covered with paracrystalline arrays of a major integral membrane protein, IP39, a putative four-membrane-spanning protein with the conserved sequence motif of the PMP-22/EMP/MP20/Claudin superfamily. Here we report the three-dimensional structure of Euglena IP39 determined by electron crystallography. Two-dimensional crystals of IP39 appear to form a striated pattern of antiparallel double-rows in which trimeric IP39 units are longitudinally polymerised, resulting in continuously extending zigzag-shaped lines. Structural analysis revealed an asymmetric molecular arrangement in the trimer, and suggested that at least four different interactions between neighbouring protomers are involved. A combination of such multiple interactions would be important for linear strand formation of membrane proteins in a lipid bilayer.

  9. 78 FR 56908 - 30-Day Notice of Proposed Information Collection: Training Evaluation Form

    Science.gov (United States)

    2013-09-16

    ... URBAN DEVELOPMENT 30-Day Notice of Proposed Information Collection: Training Evaluation Form AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice. SUMMARY: HUD has submitted the proposed... Information Collection Title of Information Collection: Training Evaluation Form. OMB Approval Number:...

  10. QUALITY EVALUATION OF THE TPP POWER GENERATING UNITS WEAR RECONDITIONING

    Directory of Open Access Journals (Sweden)

    E. M. Farhadzadeh

    2016-01-01

    Full Text Available Reconditioning of the power generating unit worn equipment and devices is conducted during the scheduled repair period. Quality of wear reconditioning is evaluated by technical state and repair work implementation. Quality of the repair work execution characterizes logistical activities of the power station and the repair services and is rated by a five-grade scale. There are three technical conditions: adequate, subject to reservations, falling short of the technical standard documentation requirements. In practical work these constraints give place to essential ambiguity of the decision. Further to regulating techniques by way of informational support, the authors propose conducting the wear-reconditioning quality evaluation (repair quality accordingly the technical-and-economic indexes pattern of change. The paper recommends applying similarly the fivegrade system in evaluating the power generating unit technical state and distinguishes intolerable, dissatisfactory, fair, good and model estimates. The study demonstrates the assessment criteria dependence on the character of reliability and economical efficiency of performance variation after the repair with increase or decrease of the technical-and-economic indexes in reference to their mean, minimum and maximum values before the repair. The cases ascribed to intolerable quality of the wear reconditioning are those with one or more technical-and-economic indexes that not only failed to improve their values but deteriorated, and at that they became the worst amongst observable values. The model quality estimate of the wear reconditioning is allotted under condition that the power unit technical-and-economic index valuations after the repair not merely improved but also exceeded the best among those under observation. The developed method and algorithm for quality evaluation of the scheduled repair implementation contribute to practical realization of the independent monitoring. This monitoring

  11. Rat granulocyte colony-forming unit (CFU-G) assay for the assessment of drug-induced hematotoxicity.

    Science.gov (United States)

    Matsumura-Takeda, K; Kotosai, K; Ozaki, A; Hara, H; Yamashita, S

    2002-06-01

    To assess the drug-induced hematotoxicity to granulocyte progenitors, we established a modified colony-forming assay using rat bone marrow cells (BMCs). In the presence of various colony-stimulating factors (CSFs), rat BMCs were disseminated on methylcellulose at a concentration of 1.3 x 10(4) cells/cm(2) (5 x 10(4) cells/0.5 ml/well in a 12-well plate). Mouse granulocyte-macrophage colony-stimulating factor (mGM-CSF) stimulated the formation of almost all macrophage colonies. Human granulocyte colony-stimulating factor (hG-CSF) alone or in combination with mouse interleukin-3 (mIL-3) did not significantly effect on the number of rat colony-forming units in culture (CFU-C). When BMCs were seeded at 5.2 x 10(4) cells/cm(2) (5 x 10(5) cells/1 ml/dish in a 35-mm dish), hG-CSF increased the number of the colonies in a dose-dependent manner, and resulted in about 50 colonies at 50 ng/ml. The constituent cells of the colonies were identified as neutrophils. Under these conditions, the effects of 5-fluorouracil (5-FU) on granulocyte colony-forming units (CFU-G) were examined in rats and mice. The inhibitory effect of 5-FU on rat CFU-G was similar to the effect on mouse CFU-G. These results indicate that the rat CFU-G induced by hG-CSF is capable of being used for the evaluation of drug-induced hematotoxicity.

  12. Evaluation of hot forming effects mapping for CAE analyses

    Science.gov (United States)

    Knoerr, L.; Faath, T.; Dykeman, J.; Malcolm, S.

    2016-08-01

    Hot forming has grown significantly in the manufacturing of structural components within the vehicle Body-In-White construction. The superior strength of press hardened steels not only guarantee high resistance to deformation, it also brings a significant weight saving compared to conventional cold formed products. However, the benefit of achieving ultrahigh strength with hot stamping, comes with a reduction in ductility of the press hardened part. This will require advanced material modeling to capture the predicted performances accurately. A technique to optically measure and map the thinning distribution after hot stamping has shown to improve numerical analysis for fracture prediction. The proposed method to determine the forming effects and mapping to CAE models can be integrated into the Vehicle Development Process to shorten the time to production.

  13. Comprehensive life extension evaluated for three-unit station

    Energy Technology Data Exchange (ETDEWEB)

    Morris, C.; Field, J.R.; Wittig, S.

    1988-01-01

    This is an account of a project carried out at the Independence City Power and Light's Blue Valley Station, Missouri, USA. The purpose of this project was to assess the condition of each of the three generating units, to investigate the feasibility and cost of a life extension and turbine capacity improvement program, and to make recommendation for life extension measures. The effort was prompted by deteriorating performance and availability of the units. Also considered were plant modifications to meet anticipated stricter environmental regulations such as acid rain legislation. This project has demonstrated the benefits of a comprehensive program that evaluates the entire plant condition rather than simply reacting to problems as they occur. 2 figs., 5 tabs.

  14. Preliminary evaluation of alternative waste form solidification processes. Volume II. Evaluation of the processes

    Energy Technology Data Exchange (ETDEWEB)

    1980-08-01

    This Volume II presents engineering feasibility evaluations of the eleven processes for solidification of nuclear high-level liquid wastes (HHLW) described in Volume I of this report. Each evaluation was based in a systematic assessment of the process in respect to six principal evaluation criteria: complexity of process; state of development; safety; process requirements; development work required; and facility requirements. The principal criteria were further subdivided into a total of 22 subcriteria, each of which was assigned a weight. Each process was then assigned a figure of merit, on a scale of 1 to 10, for each of the subcriteria. A total rating was obtained for each process by summing the products of the subcriteria ratings and the subcriteria weights. The evaluations were based on the process descriptions presented in Volume I of this report, supplemented by information obtained from the literature, including publications by the originators of the various processes. Waste form properties were, in general, not evaluated. This document describes the approach which was taken, the developent and application of the rating criteria and subcriteria, and the evaluation results. A series of appendices set forth summary descriptions of the processes and the ratings, together with the complete numerical ratings assigned; two appendices present further technical details on the rating process.

  15. Evaluation of metrology technologies for free form surfaces

    DEFF Research Database (Denmark)

    Arámbula, K.; Siller, H.R.; De Chiffre, Leonardo

    2012-01-01

    This research work describes a novel approach for comparing different technologies for free form surface metrology: computerized tomography (CT), photogrammetry and coordinate measuring machines (CMM). The comparison has the aim of providing relevant information for the selection of metrology...... also deals with costs issues, required standards, and necessary additional information when selecting inspection equipment....

  16. Evaluation of metrology technologies for free form surfaces

    DEFF Research Database (Denmark)

    Arámbula, K.; Siller, H.R.; De Chiffre, Leonardo

    2012-01-01

    This research work describes a novel approach for comparing different technologies for free form surface metrology: computerized tomography (CT), photogrammetry and coordinate measuring machines (CMM). The comparison has the aim of providing relevant information for the selection of metrology...... also deals with costs issues, required standards, and necessary additional information when selecting inspection equipment....

  17. The Analysis, Evaluation and Adaptation of Unit 6 When was it invented?%The Analysis,Evaluation and Adaptation of Unit 6 When was it invented?

    Institute of Scientific and Technical Information of China (English)

    张蕊

    2016-01-01

    Materials play a significant role in English teachingand learning. This thesis evaluates Unit 6 When was it invented?by internal evaluation and external evaluation and puts forward some specific adaptation.

  18. Aeromonas spp.: evaluation of genomic diversity and biofilm forming ability

    OpenAIRE

    Craveiro, Sara Sofia Pereira, 1986-

    2013-01-01

    Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2013 Aeromonas spp. are ubiquitous bacteria widely distributed among aquatic environments. Their persistence in water distribution systems is related to their ability to form biofilms, even in the presence of residual chlorine. Once in distribution water systems, aeromonads can contaminate drinking water, food processing facilities and food products. Moreover, members of this genus are known...

  19. PROCESS SIMULATION AND QUALITY EVALUATION IN INCREMENTAL SHEET FORMING

    Directory of Open Access Journals (Sweden)

    Meftah Hrairi

    2011-12-01

    Full Text Available Single Point Incremental Forming (SPIF is a promising sheet-metal-forming process that permits the manufacturing of small to medium-sized batches of complex parts at low cost. It allows metal forming to work in the critical ‘necking-to-tearing' zone which results in a strong thinning before failure if the process is well designed. Moreover, the process is complex due to the number of variables involved. Thus, it is not possible to consider that the process has been well assessed; several remaining aspects need to be clarified. The objective of the present paper is to study some of these aspects, namely, the phenomenon of the wall thickness overstretch along depth and the effect of the tool path on the distribution of the wall thickness using finite element simulations.Abstrak: Pembentukan Tokokan Mata Tunggal (Single Point Incremental Forming (SPIF merupakan satu proses pembentukan kepingan logam yang membolehkan pembuatan dalam jumlah yang kecil hingga sederhana, bahagian-bahagian yang kompleks pada kos yang rendah. Jika proses ini direka dengan baik, kaedah ini membolehkan pembentukan logam yang baik terhasil. Jika tidak, semasa peringkat zon kritikal ‘perleheran-ke-pengoyakan' menyebabkan penipisan keterlaluan yang boleh menyebabkan logam tersebut rosak. Tambahan pula, proses ini agak kompleks, kerana ia melibatkan beberapa pemboleh ubah. Maka, walaupun proses ini telah dinilaikan seeloknya; masih terdapat beberapa aspek lain yang perlu diperjelaskan. Objektif kertas ini dibentangkan adalah untuk mengkaji beberapa aspek tertentu, seperti, ketebalan dinding regangan berlebihan di sepanjang kedalaman dan kesan tool path (beberapa siri posisi koordinat untuk menentukan pergerakan alatan memotong ketika operasi memesin terhadap pengagihan ketebalan dinding menggunakan simulasi unsur terhingga.

  20. 28 CFR 1100.35 - Authority to permit continued presence in the United States for victims of severe forms of...

    Science.gov (United States)

    2010-07-01

    ... encounter alien victims of severe forms of trafficking in persons who are potential witnesses to that... the United States for victims of severe forms of trafficking in persons. 1100.35 Section 1100.35 Judicial Administration DEPARTMENT OF JUSTICE AND DEPARTMENT OF STATE TRAFFICKING IN PERSONS Victims of...

  1. 75 FR 55586 - Submission for OMB Review; Comment Request Cancer Trials Support Unit (CTSU) Public Use Forms and...

    Science.gov (United States)

    2010-09-13

    ... Support Unit (CTSU) Public Use Forms and Customer Satisfaction Surveys (NCI) SUMMARY: Under the provisions... Forms 2 CTSU Web Site Customer 250 10-15 0.2500 1.00 63 Satisfaction Survey. 3 CTSU Helpdesk Customer... of customer satisfaction for clinical site staff using the CTSU Help Desk and the CTSU Web site. An...

  2. Constitution of the forest road evaluation form for Turkish forestry

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-19

    Oct 19, 2009 ... wild habitats 5.63%; eligibility for forestry works 2.64% and eligibility for utilization for security 6.45%. The evaluation ... establishment and maintenance of forest road networks. However ..... J. Civil Eng. 33: 58-68. Forman EH ...

  3. Leasing versus Borrowing: Evaluating Alternative Forms of Consumer Credit.

    Science.gov (United States)

    Nunnally, Bennie H., Jr.; Plath, D. Anthony

    1989-01-01

    Presents a straightforward method for evaluating lease versus borrow (buy) decisions illustrated with actual financing cost data reported to new car purchasers. States that individuals should consider after-tax cash flows associated with alternative arrangements, time in which cash flow occurs, and opportunity cost of capital to identify the least…

  4. Channel Networks on Large Fans: Refining Analogs for the Ridge-forming Unit, Sinus Meridiani

    Science.gov (United States)

    Wilkinson, Justin

    2009-01-01

    Stream channels are generally thought of as forming within confined valley settings, separated by interfluves. Sinuous ridges on Mars and Earth are often interpreted as stream channels inverted by subsequent erosion of valley sides. In the case of the ridge-forming unit (RFU), this interpretation fails to explain the (i) close spacing of the ridges, which are (ii) organized in networks, and which (iii) cover large areas (approximately 175,000 km (exp 2)). Channel networks on terrestrial fans develop unconfined by valley slopes. Large fans (100s km long) are low-angle, fluvial features, documented worldwide, with characteristics that address these aspects of the RFU. Ridge patterns Channels on large fans provide an analog for the sinuous and elongated morphology of RFU ridges, but more especially for other patterns such as subparallel, branching and crossing networks. Branches are related to splays (delta-like distributaries are rare), whose channels can rejoin the main channel. Crossing patterns can be caused by even slight sinuosity splay-related side channels often intersect. An avulsion node distant from the fan apex, gives rise to channels with slightly different, and hence intersecting, orientations. Channels on neighboring fans intersect along the common fan margin. 2. Network density Channels are the dominant feature on large terrestrial fans (lakes and dune fields are minor). Inverted landscapes on subsequently eroded fans thus display indurated channels as networks of significantly close-spaced ridges. 3. Channel networks covering large areas Areas of individual large terrestrial fans can reach >200,000 km 2 (105-6 km 2 with nested fans), providing an analog for the wide area distribution of the RFU.

  5. Elimination of 5S DNA unit classes in newly formed allopolyploids of the genera Aegilops and Triticum.

    Science.gov (United States)

    Baum, B R; Feldman, M

    2010-06-01

    Two classes of 5S DNA units, namely the short (containing units of 410 bp) and the long (containing units of 500 bp), are recognized in species of the wheat (the genera Aegilops and Triticum) group. While every diploid species of this group contains 2 unit classes, the short and the long, every allopolyploid species contains a smaller number of unit classes than the sum of the unit classes of its parental species. The aim of this study was to determine whether the reduction in these unit classes is due to the process of allopolyploidization, that is, interspecific or intergeneric hybridization followed by chromosome doubling, and whether it occurs during or soon after the formation of the allopolyploids. To study this, the number and types of unit classes were determined in several newly formed allotetraploids, allohexaploids, and an allooctoploid of Aegilops and Triticum. It was found that elimination of unit classes of 5S DNA occurred soon (in the first 3 generations) after the formation of the allopolyploids. This elimination was reproducible, that is, the same unit classes were eliminated in natural and synthetic allopolyploids having the same genomic combinations. No further elimination occurred in the unit classes of the 5S DNA during the life of the allopolyploid. The genetic and evolutionary significance of this elimination as well as the difference in response to allopolyploidization of 5S DNA and rDNA are discussed.

  6. Improving emergency department flow through Rapid Medical Evaluation unit.

    Science.gov (United States)

    Chartier, Lucas; Josephson, Timothy; Bates, Kathy; Kuipers, Meredith

    2015-01-01

    The Toronto Western Hospital is an academic hospital in Toronto, Canada, with an annual Emergency Department (ED) volume of 64,000 patients. Despite increases in patient volumes of almost six percent per annum over the last decade, there have been no commensurate increases in resources, infrastructure, and staffing. This has led to substantial increase in patient wait times, most specifically for those patients with lower acuity presentations. Despite requiring only minimal care, these patients contribute disproportionately to ED congestion, which can adversely impact resource utilization and quality of care for all patients. We undertook a retrospective evaluation of a quality improvement initiative aimed at improving wait times experienced by patients with lower acuity presentations. A rapid improvement event was organized by frontline workers to rapidly overhaul processes of care, leading to the creation of the Rapid Medical Evaluation (RME) unit - a new pathway of care for patients with lower acuity presentations. The RME unit was designed by re-purposing existing resources and re-assigning one physician and one nurse towards the specific care of these patients. We evaluated the performance of the RME unit through measurement of physician initial assessment (PIA) times and total length of stay (LOS) times for multiple groups of patients assigned to various ED care pathways, during three periods lasting three months each. Weekly measurements of mean and 90th percentile of PIA and LOS times showed special cause variation in all targeted patient groups. Of note, the patients seen in the RME unit saw their median PIA and LOS times decrease from 98min to 70min and from 165min to 130min, respectively, from baseline. Despite ever-growing numbers of patient visits, wait times for all patients with lower acuity presentations remained low, and wait times of patients with higher acuity presentations assigned to other ED care pathways were not adversely affected. By

  7. 75 FR 66767 - Submission for OMB Review; Comment Request; Cancer Trials Support Unit (CTSU) Public Use Forms...

    Science.gov (United States)

    2010-10-29

    ... Support Unit (CTSU) Public Use Forms and Customer Satisfaction Surveys (NCI) SUMMARY: Under the provisions....00 1000.00 Form. Surveys/Web Forms 2 CTSU Web Site Customer 250 10-15 0.2500 1.00 63 Satisfaction Survey. 3 CTSU Helpdesk Customer 300 10-15 0.2500 1.00 75 Satisfaction Survey. 4 CTSU OPEN Survey 120 10...

  8. Evaluation of phase separator number in hydrodesulfurization (HDS) unit

    Science.gov (United States)

    Jayanti, A. D.; Indarto, A.

    2016-11-01

    The removal process of acid gases such as H2S in natural gas processing industry is required in order to meet sales gas specification. Hydrodesulfurization (HDS)is one of the processes in the refinery that is dedicated to reduce sulphur.InHDS unit, phase separator plays important role to remove H2S from hydrocarbons, operated at a certain pressure and temperature. Optimization of the number of separator performed on the system is then evaluated to understand the performance and economics. From the evaluation, it shows that all systems were able to meet the specifications of H2S in the desired product. However, one separator system resulted the highest capital and operational costs. The process of H2S removal with two separator systems showed the best performance in terms of both energy efficiency with the lowest capital and operating cost. The two separator system is then recommended as a reference in the HDS unit to process the removal of H2S from natural gas.

  9. 48 CFR 247.372 - DD Form 1654, Evaluation of Transportation Cost Factors.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1654, Evaluation... Transportation in Supply Contracts 247.372 DD Form 1654, Evaluation of Transportation Cost Factors. Contracting personnel may use the DD Form 1654 to furnish information to the transportation office for development...

  10. Evaluation of the film-forming property of hydrogenated rosin.

    Science.gov (United States)

    Satturwar, P M; Fulzele, S V; Joshi, S B; Dorle, A K

    2003-09-01

    The film-forming and coating properties of a new biomaterial, hydrogenated rosin (HR), is investigated in the present communication. Films produced by casting method are studied for mechanical, (tensile strength, elongation, and Young's modulus), water vapor transmission, and moisture absorption characteristics. Type of plasticizer and its concentration were observed to play an important role in modifying the film characteristics. Dibutyl sebacate (DBS), a hydrophobic plasticizer, was found to be suitable for development of flexible and smooth films. Film formulations plasticized with DBS were investigated for coating the drug layered nonpareil seeds where plasticization facilitated development of smooth and uniformly coated pellets. The increase in coat buildup, however, did not sustain the drug release significantly. The studies conclude that HR films promise utility as moisture-protective hydrophobic, film-coating materials.

  11. Subjective Evaluation of Forms in an Immersive Environment

    CERN Document Server

    Petiot, Jean-François

    2003-01-01

    User's perception of product, by essence subjective, is a major topic in marketing and industrial design. Many methods, based on users' tests, are used so as to characterise this perception. We are interested in three main methods: multidimensional scaling, semantic differential method, and preference mapping. These methods are used to built a perceptual space, in order to position the new product, to specify requirements by the study of user's preferences, to evaluate some product attributes, related in particular to style (aesthetic). These early stages of the design are primordial for a good orientation of the project. In parallel, virtual reality tools and interfaces are more and more efficient for suggesting to the user complex feelings, and creating in this way various levels of perceptions. In this article, we present on an example the use of multidimensional scaling, semantic differential method and preference mapping for the subjective assessment of virtual products. These products, which geometrical...

  12. Formulation and evaluation of gastroretentive dosage forms of Clarithromycin.

    Science.gov (United States)

    Nama, Muralidhar; Gonugunta, Chandra Sekhar Rao; Reddy Veerareddy, Prabhakar

    2008-01-01

    The purpose of this research was to develop the hydrodynamically balanced delivery system of Clarithromycin (CLA) which, after oral administration should have the ability to prolong gastric residence time with the desired in vitro release profile for the localized action in the stomach, in the treatment of Helicobacter pylori (H.pylori) mediated peptic ulcer. By applying wet granulation technique floating tablets of Clarithromycin were prepared. The proportion of sodium bicarbonate was varied to get the least possible lag time, also the polymer part varied to get the desired release. In vivo radiographic studies were performed with Barium sulphate loaded formulation to justify the increased gastric residence time of the dosage form in the stomach, based on the floating principle. The formulation developed using 66.2% Clarithromycin, 12% HPMC K4M polymer, 8% sodium bicarbonate gave floating lag time less than 3 min with a floating time of 12 h, and an in vitro release profile very near to the desired release. X-ray studies showed the enhanced gastric residence time of the tablet to 220 +/- 30 min. The mechanism of release of Clarithromycin from the floating tablets is anomalous diffusion transport and follows zero order kinetics. In vivo radiographic studies suggest that the tablet has increased gastric residence time for the effective localized action of the antibiotic (Clarithromycin) in the treatment of H.pylori mediated peptic ulcer.

  13. Least squares evaluations for form and profile errors of ellipse using coordinate data

    Science.gov (United States)

    Liu, Fei; Xu, Guanghua; Liang, Lin; Zhang, Qing; Liu, Dan

    2016-09-01

    To improve the measurement and evaluation of form error of an elliptic section, an evaluation method based on least squares fitting is investigated to analyze the form and profile errors of an ellipse using coordinate data. Two error indicators for defining ellipticity are discussed, namely the form error and the profile error, and the difference between both is considered as the main parameter for evaluating machining quality of surface and profile. Because the form error and the profile error rely on different evaluation benchmarks, the major axis and the foci rather than the centre of an ellipse are used as the evaluation benchmarks and can accurately evaluate a tolerance range with the separated form error and profile error of workpiece. Additionally, an evaluation program based on the LS model is developed to extract the form error and the profile error of the elliptic section, which is well suited for separating the two errors by a standard program. Finally, the evaluation method about the form and profile errors of the ellipse is applied to the measurement of skirt line of the piston, and results indicate the effectiveness of the evaluation. This approach provides the new evaluation indicators for the measurement of form and profile errors of ellipse, which is found to have better accuracy and can thus be used to solve the difficult of the measurement and evaluation of the piston in industrial production.

  14. The inductive form of preaching (F.B. Craddock – an exploration and evaluation

    Directory of Open Access Journals (Sweden)

    C. J.H Venter

    2005-07-01

    Full Text Available Within the wider field of research in homiletics special emphasis has been placed on investigation dealing with hermeneutical homiletics. In Europe Dingemans initiated research focused on this specific field of homiletics in 1991. In South Africa the research and findings of Pieterse and Vos on hermeneutical homiletics are prominent at this stage. The emphasis in research on this aspect of homiletics has, however, in a sense been preceded by the work of Fred Craddock – work that has till date not been highlighted and evaluated sufficiently by South African theologians. Craddock’s work in this field may be regarded as transitional in nature. In Craddock’s approach the focus has shifted from research dealing mainly with the formal aspects of preaching to research bringing into perspective, among others, an inductive form of preaching. In applying the inductive form of preaching the function of the hearer as interpreter is utilised. The power and generative use of language in a sermon is also brought to the fore in this form of preaching. Craddock has indeed brought to light core elements in homiletical research – elements still serving as a stimulus for research on hermeneutical homiletics. Craddock’s approach to preaching – the inductive method – directs the attention to the structure of the sermon, as well as the “movements” and the development of the train of thought within the sermon as essential elements of inductive preaching. Furthermore, the aim of uniting the different elements of the sermon and the use of imaginative language in a sermon is also stressed by Craddock’s method. In conclusion this article attempts an evaluation of some of Craddock’s viewpoints on preaching.

  15. [Evaluation of the welcoming strategies in the Intensive Care Unit].

    Science.gov (United States)

    Maestri, Eleine; do Nascimento, Eliane Regina Pereira; Bertoncello, Kátia Cilene Godinho; de Jesus Martins, Josiane

    2012-02-01

    This qualitative study was performed at the adult Intensive Care Unit (ICU) of a public hospital in Southern Brazil with the objective to evaluate the implemented welcoming strategies. Participants included 13 patients and 23 relatives. Data collection was performed from July to October 2008, utilizing semi-structured interviews. All interviews were recorded. Data analysis was performed using the Collective Subject Discourse. The collected information yielded two discourses: the family recognized the welcoming strategies and the patients found the ICU team to be considerate. By including the family as a client of nursing care, relatives felt safe and confident. Results show that by committing to the responsibility of making changes in heath care practices, nurses experience a novel outlook towards ICU care, focused on human beings and associating the welcoming to the health care model that promotes the objectivity of care.

  16. Evaluation of New Schemes Efficacy for Blatta Orientalis and Blattella Germanica Control in Food Units with HACCP Implementation

    Directory of Open Access Journals (Sweden)

    VINELA REFUGJATI

    2015-12-01

    Full Text Available Blatta orientalis and Blattella germanica are the most common pests in the food industry. The aim of this study is the evaluation of new treatment schemes effectiveness as well as the monetary cost, humans and environment toxicity against Blatta orientalis and Blattella germanica. The study was carried out in 28 food units infested with Blattella germanica and Blatta orientalis in Tirana. The duration of the study was 24 months. The treatment efficacy of 2.15% imidacloprid (in gel form is tested for 12 months, in thirteen units meanwhile one unit served as a control unit. The monetary cost of insecticide mentioned was calculated using the quantity and treatment duration of insecticide applied. For this reason, we calculated the quantity of gel baits used in seven food units as well as the quantity of insecticide in spray form used in seven others food units for a period of 12 months. Technical and safety data sheets were used to assess human and environment safety. Insect elimination was achieved by the end of the ninth week. This study found that in the units which used imidacloprid the short term cost was 21 Euro / unit, while in other units which used the classic method the cost was 8.3 Euro / unit. Our study identified that at the units which used imidacloprid the annual cost was 68 Euro while in the other category the cost was 78 Euro.Technical and safety data sheets detected that insecticides in gel form are safer for human and environment. As in analog studies conducted by foreign researchers, we found that the use of insecticides in gel form is the right choice for Blatta orientalis and Blattella germanica control.

  17. Evaluating Mobile Graphics Processing Units (GPUs) for Real-Time Resource Constrained Applications

    Energy Technology Data Exchange (ETDEWEB)

    Meredith, J; Conger, J; Liu, Y; Johnson, J

    2005-11-11

    Modern graphics processing units (GPUs) can provide tremendous performance boosts for some applications beyond what a single CPU can accomplish, and their performance is growing at a rate faster than CPUs as well. Mobile GPUs available for laptops have the small form factor and low power requirements suitable for use in embedded processing. We evaluated several desktop and mobile GPUs and CPUs on traditional and non-traditional graphics tasks, as well as on the most time consuming pieces of a full hyperspectral imaging application. Accuracy remained high despite small differences in arithmetic operations like rounding. Performance improvements are summarized here relative to a desktop Pentium 4 CPU.

  18. An impact evaluation of a newly developed pediatric cardiac intensive care unit.

    Science.gov (United States)

    Welander, Michelle Hanna; Keller, Sheila D; Northington, LaDonna

    2015-01-01

    The highly complex pediatric patients with congenital heart disease require interprofessional teamwork and collaboration to ensure high-quality outcomes with low mortality and morbidity (Congenit Heart Dis. 2013;8:3-19). The purpose of this study was to conduct an impact evaluation for a newly formed pediatric cardiac intensive care unit (PCICU) and to answer: Is there a difference between the pediatric intensive care unit and the PCICU on clinical outcome measures of pediatric cardiac postoperative patients and nursing resources? A retrospective pretest/posttest design was used with the independent variables being type of intensive care unit. The confounding variables included demographic data, clinical outcome data, registered nurse (RN) staffing data, and RN turnover data. The setting was a large, level I pediatric medical and surgical intensive care unit (ICU) located at a children's hospital within an academic medical center. The population was pediatric cardiac postoperative patients. Patients excluded were those older than 18 years or cases without a Society of Thoracic Surgeons and European Association for Cardiothoracic Surgery Congenital Heart Surgery Mortality Category score of 1 through 5. Owen's impact evaluation method and descriptive statistical measures, t test and Pearson χ test, were used for analysis. Demographic data were comparable between the pediatric intensive care unit (n = 296) and PCICU (n = 333). No statistical differences were found in several of the clinical outcome measures. Statistically significant differences were found in surgeon (P = .00) and RN nursing hours per patient day for all cardiac patients (P = .01). The PCICU time frame had a higher RN turnover rate. The majority of quality measures were not statistically different between the 2 ICUs. Even though statistical significance was not reached, the clinical impact of the PCICU's reduction in patient infections, mortality, and ICU length of stay was noted. This evaluation has

  19. Baseline correlation and comparative kinetics of cerebrospinal fluid colony-forming unit counts and antigen titers in cryptococcal meningitis.

    NARCIS (Netherlands)

    Brouwer, A.E.; Teparrukkul, P.; Pinpraphaporn, S.; Larsen, R.A.; Chierakul, W.; Peacock, S.; Day, N.; White, N.J.; Harrison, T.S.

    2005-01-01

    Cerebrospinal fluid (CSF) cryptococcal colony-forming unit counts and CSF cryptococcal antigen titers serve as alternative measures of organism load in cryptococcal meningitis. For these measures, we correlated baseline values and rates of decline during the first 2 weeks of therapy in 68 human immu

  20. Evaluation of an Observer Form of the Coping Inventory for Stressful Situations

    Science.gov (United States)

    Han, Kyunghee; Burns, Gary N.; Weed, Nathan C.; Hatchett, Gregory T.; Kurokawa, Nancy K. S.

    2009-01-01

    The present study evaluates a prospective observer form of the Coping Inventory for Stressful Situations (CISS) by comparing the two forms in terms of factor structure, mean differences, reliability, and examining correlations between self-report and peer ratings. A total of 163 pairs of friends complete the CISS and an observer form of the CISS.…

  1. Evaluation of retention protocols among members of the American Association of Orthodontists in the United States

    Science.gov (United States)

    Pratt, Michael C.; Kluemper, George Thomas; Hartsfield, James K.; Fardo, David; Nash, David A.

    2016-01-01

    Introduction Little research has been conducted to evaluate protocols and trends in orthodontic retention. The purpose of this study was to identify the general retention protocols used by orthodontists in the United States. Additionally, our goal was to identify trends in these orthodontic retention protocols by evaluating how they have changed over the past 5 years and how they might continue to change in the next 5 years. Methods The study was conducted via a 36-question electronic survey (REDCap, Nashville, Tenn) with branching logic on certain questions. The survey was sent to all 9143 practicing members of the American Association of Orthodontists in the United States, and 1632 (18%) responded. Results and Conclusions Mean retention protocols of the surveyed population showed predominant use of Hawley or vacuum-formed retainers in the maxillary arch and fixed retention in the mandibular arch. For both arches, there is a current shift away from Hawley retainers and toward vacuum-formed retainers and fixed retention. Respondents who extract fewer teeth reported increased use of fixed retention in the maxillary (P = 0.041) and mandibular (P = 0.003) arches. Respondents who extract fewer teeth and use removable retainers were more likely to tell their patients to wear their retainers at night for the rest of their lives (P = 1.63 × 10−6). PMID:21967939

  2. A Form Evaluation System and Its Data Structure for Brosh—Written Chinese Characters

    Institute of Scientific and Technical Information of China (English)

    曾建超; HidehikoSanada; 等

    1995-01-01

    A form evaluation system for brush-written Chinese characters is developed.Calligraphic knowledge used in the system is represented in the form of rules with the help of a data structure proposed in this paper.Reflecting the specific hierarchical relations among radicals and strokes of Chinese characters,the proposed data structure is based upon a character model that can generate brush-written Chinese characters on a computer.Through evaluation experiments using the developed system,it is shown that representation of calligraphic knowledge and form evaluation of Chinese characters can be smoothly realized if the data structure is utilized.

  3. Respiratory Distress in Neonatal Intensive Care Unit: A Retrospective Evaluation

    Directory of Open Access Journals (Sweden)

    Ali Annagur

    2012-04-01

    Full Text Available Purpose: To determine the demographic characteristics of the newborns with respiratory difficulties, frequency of neonatal disease, analyze of the prognostic factors and effectiveness of treatment who were hospitalized in neonatal intensive care unit (NICU. Methods: In this study, file records of the newborns who were hospitalized in NICU of Meram Medical School were analyzed retrospectively. Results: Of the 771 newborns, 225 who admitted due to respiratory distress in 2008 and of the 692 newborns, 282 who admitted due to respiratory distress in 2009. Mean birth weight was 1954±972 gr in 2008, and 2140±1009 gr in 2009. Mean pregnancy weeks were 32,4±5,0 in 2008 and 33,4±4,9 in 2009. Diagnosis of patients were sepsis (77,8%, respiratory distress syndrome (RDS (40,4%, pneumothorax (20,9%, patent ductus arteriosus (PDA (12,4%, meconium aspiration syndrome (MAS (6,2%, intraventricular hemorrhage (IVH (5,3%, pneumonia (3,6%, retinopathy of prematurely (ROP (3,1%, bronchopulmonary dysplasia (BPD (2,7% and transient tachypne of newborn (TTN (2,2% in 2008. In 2009, percentage of the diagnosis was 69,5% sepsis, 33,3% RDS, 17,0% PDA, 16,0% pneumothorax, 10,3% pneumonia, 8,2% IVH, 6% TTN, 5,3% BPD, 3,2% MAS and 3,2% ROP. 33.7% of the patients were died in 2009 and 43,6% of them in 2008. Conclusion: The newborns with respiratory distress who admitted to the hospital must be evaluated according to the pregnancy week, way of birth and accompanying problems during first examination and convenient transportation of the ones who need to be cared in advanced center where an intensive care support can be applied to decrease mortality and morbidity of newborns distress. [Cukurova Med J 2012; 37(2.000: 90-97

  4. Evaluation of a compact portable DEXA unit for wrist densitometry

    Energy Technology Data Exchange (ETDEWEB)

    Mares, T.; Bonovas, G.; Larcos, G. [Westmead Hospital, Sydney, NSW (Australia). Department of Nuclear Medicine

    1998-06-01

    Full text: Recently, a number of manufacturers have introduced compact, portable DEXA units in order to facilitate osteoporosis screening in remote communities and on an in-office basis. The purposes of this study were to evaluate the accuracy and reproducibility of the Norland-Stratec (pDEXA) compared to measurements obtained using a conventional densitometer (Norland XR-36). We recruited 61 adults (3 men, 58 women) with mean age 54 years (range: 19-76) referred for clinical assessment of BMD. Most patients had medications (n=39; 64%) or disorders (n=48;79%) known to interfere with bone mineral metabolism. Subjects underwent bone densitometry of the lumbar spine, (AP; L2-4) femoral neck and distal radius/ulna of the nondominant forearm using the Norland XR-36, with the wrist subsequently re-scanned on pDEXA. Four subjects also underwent 5 scans each on the pDEXA. Mean BMD for the distal radius/ulna was 0.30g/cm2 (range: 0.17 - 0.539/cm2; XR-36) vs 0.319/cm2 (range: 0.18-0.56 g/cm2; pDEXA), r = 0.98 (SEE = 0.07). Mean BMC for the distal radius/ulna was 1.229 (range: 0.67-2.59; XR-36) vs 1.289 (range:0.74-2.69; pDEXA), r = 0.97 (SEE= 0.08). The CV for pDEXA was 0.8% (BMD) and 2.5% (BMC). Thus, we conclude that pDEXA has excellent in-vivo reproducibility, with good correlation of BMD and BMC with standard densitometers

  5. The feasibility, reliability, and validity of a post-encounter form for evaluating clinical reasoning.

    NARCIS (Netherlands)

    Durning, S.J.; Artino, A.; Boulet, J.; Rochelle, J. La; Vleuten, C.P.M. van der; Arze, B.; Schuwirth, L.

    2012-01-01

    BACKGROUND: Developing feasible, reliable and valid methods for the evaluation of clinical reasoning is challenging. AIM: To explore feasibility, reliability, and validity evidence for a post-encounter form assessing clinical reasoning. METHOD: A free-text, post-encounter form was used in an Objecti

  6. Evaluation of Suppression of Hydroprocessed Renewable Jet (HRJ) Fuel Fires with Aqueous Film Forming Foam (AFFF)

    Science.gov (United States)

    2011-07-01

    AFRL-RX-TY-TR-2011-0101 EVALUATION OF SUPPRESSION OF HYDROPROCESSED RENEWABLE JET (HRJ) FUEL FIRES WITH AQUEOUS FILM FORMING FOAM ( AFFF ...Forming Foam ( AFFF ) has the capability of extinguishing HRJ fuel fires and HRJ/JP-8 blended fuel fires . The assessment included extinguishment...whether existing aqueous film- forming foam ( AFFF ) firefighting agents and equipment are capable of extinguishing alternative- fuel fires or

  7. Do different populations of Aphanius dispar in Southern Iran form Operational Taxonomic Units (OUTs?

    Directory of Open Access Journals (Sweden)

    Azad Teimori

    2015-10-01

    Full Text Available Deciphering the exact fundamental relations of morphological differentiation among isolated populations of animal species is generally difficult. Usually changes in morphology are resulted from adaptation to different environmental conditions (ecoplasticity or represent an expression of genetic differences and/or gene pool pauperization, and in most instances, however, changes in morphology are the result of the interplay between environmental factors and genetic plasticity. In this study, the morphology and molecular phylogenies of common tooth-carp populations (Aphanius dispar were studied in three basins in Southern part of Iran to discuss an important aspect relate to the question whether morphologically differentiated populations of a single species function as Operational Taxonomic Units. All morphological analyses were revealed significant and strong morphological differentiation between the populations that corresponds well with their zoogeography and their molecular phylogeny in geographically isolated basins. Therefore, it can be concluded that when the interaction between gene flow among populations and natural selection is resulted owing to a long evolutionary history, then the observed morphological differences can be functioned as different Operational Taxonomic Units (OTUs in subspecies or even species levels. In addition, biological characteristics of the A. dispar, its high tolerance, geological and ecological conditions in Southern Iran are the main factors that increase chance of reproductive isolation and genetic diversity in this region.

  8. Breastfeeding Evaluation Indicators System is a Promising Evaluation Tool for Preterm Infants in Neonatal Intensive Care Units (NICU).

    Science.gov (United States)

    Yu, Xiurong; Sun, Hongying; Lin, Xiangyun; Liu, Xiuxiang

    2016-10-26

    BACKGROUND Breast feeding can enhance preterm infants' neurodevelopmental outcome, regulate immune function development. This study aims to develop breastfeeding evaluation indicators system in neonatal intensive care units (NICU) and to provide theoretical basis for all-round evaluation of breast feeding quality for hospitalized preterm infants. MATERIAL AND METHODS This study was performed based on Avedis Donabedian's theory of medical care quality. Preterm infant breast feeding evaluation indicators system frame was initially formed by using literature review, clinical on-spot observation and expert consultation methods. By using specialists meeting method and Delphi method, evaluation indicators system for preterm infants breastfeeding was verified and established. Breastfeeding evaluation indicators system were performed in NICU of hospitals in Binzhou and Shanghai. Feasibility and usability of indicators system were examined. RESULTS Breastfeeding evaluation indicators system for preterm infants comprise 3 levels, including level 1 (3 indicators), level 2 (7 indicators), and level 3 (18 indicators). Recognition rates of importance for level 2 and 3 range from 94.4% to 100.0% and 80.6% to 100.0%, respectively. Mean of Likert rating for level 2 and 3 range from 3.31 to 3.89 and 3.03 to 3.97, which are all higher than the average value of 2.50. Kendall's coefficient and its significance test showed that consistency of experts' opinion for indicators' importance is high (Pquality in NICUs. CONCLUSIONS Indicators system is feasible and is a promising evaluation tool for continuously improving breastfeeding quality for preterm infants in NICUs.

  9. The Components of Smile Design: New York University Smile Evaluation Form Revisited, Update 2015.

    Science.gov (United States)

    Calamia, John R; Wolff, Mark S

    2015-07-01

    This article updates a simple checklist of foundational knowledge in aesthetic dental concepts that allows clinicians to organize their thoughts, to record the concerns of the patient, and to map out those improvements that must be addressed. This adjunct is called a Smile Evaluation Form. Along with other adjuncts such as radiographs, study casts, and diagnostic wax-ups, the Smile Evaluation Form allows clinicians to form a conceptual visualization of the expected end point. It provides a checklist for discussions with other disciplines in the team, to provide a logical sequence of treatment with a mutually agreed-on end point.

  10. A device for forming an assignment for a pressure regulator in a power producing unit

    Energy Technology Data Exchange (ETDEWEB)

    Turchaninov, B.V.; German, V.S.; Yurov, A.I.

    1982-01-01

    The assigned value of the steam pressure in front of a turbine is the sum of a correcting signal based on the position of the turbine valves and the loading signal which is sequentially transformed in two nonlinear elements and an integral and differential link. The second nonlinear element forms limitations on the minimal and maximal assigned values. The imbalance of the input and output signals of this element is fed to the input of the valve position corrector and makes it possible to switch this regulator into a constant pressure mode.

  11. Thea 'tricks': forms of resistance in the 1968 United States and after

    OpenAIRE

    Chazalon, Elodie

    2015-01-01

    The year 1968 seems to be the climax of the counterculture, as manifold forms of resistance emerged and multiple claims were asserted by various social groups. Such a polyphony may appear as a hodgepodge of uncoordinated elements, all the more so as 1968 seems to be the year of rifts and dissensions between “movement cultures,” radical politicized groups, and the more hedonistic and apolitical hippies. In order to show that 1968 is both a puzzle and a puzzling year which prepared the ground f...

  12. Combat Modeling Evaluation at the United States Military Academy.

    Science.gov (United States)

    1985-06-01

    ULOC)).PRCNT(ILOC) 0238 DO 110 ISUPSI,12 0239 SUPPLY(IFILE(ILOC), ISUP ).IFORCE(ILOC, ISUP ) 0240 110 CONTINUE 0241 DO 120 IWE~ul,? 0242 NUNDERVEAPONS...IWEP) 0226 70 CONTINUE 0227 DO S0 ISUP01,12 0228 IFORCE(ILOC, ISUP )mSUPPLY(LOC.ISUP) 0229 80 CONTINUE 0230 90 CONTINUE 0231 DO 290 IRONw1,IREPT 0232...EACH TYPE BY UNIT IN FILE INPUT.DAT NITCL ARRAY OF UNIT COLORS IN FILE INPUT.DAT ISUP SUPPLY CATEGORY • e IFORCE ARRAY TO STORE SUPPLIES ON HAND IN

  13. Lunar-Forming Giant Impact Model Utilizing Modern Graphics Processing Units

    Indian Academy of Sciences (India)

    J. C. Eiland; T. C. Salzillo; B. H. Hokr; J. L. Highland; W. D. Mayfield; B. M. Wyatt

    2014-12-01

    Recent giant impact models focus on producing a circumplanetary disk of the proper composition around the Earth and defer to earlier works for the accretion of this disk into the Moon. The discontinuity between creating the circumplanetary disk and accretion of the Moon is unnatural and lacks simplicity. In addition, current giant impact theories are being questioned due to their inability to find conditions that will produce a system with both the proper angular momentum and a resultant Moon that is isotopically similar to the Earth. Here we return to first principles and produce a continuous model that can be used to rapidly search the vast impact parameter space to identify plausible initial conditions. This is accomplished by focusing on the three major components of planetary collisions: constant gravitational attraction, short range repulsion and energy transfer. The structure of this model makes it easily parallelizable and well-suited to harness the power of modern Graphics Processing Units (GPUs). The model makes clear the physically relevant processes, and allows a physical picture to naturally develop. We conclude by demonstrating how the model readily produces stable Earth–Moon systems from a single, continuous simulation. The resultant systems possess many desired characteristics such as an iron-deficient, heterogeneously-mixed Moon and accurate axial tilt of the Earth.

  14. Emergy Evaluation of Educational Attainment in the United States

    Science.gov (United States)

    The emergy of educational attainment in the United States was quantified over the period for which the necessary data were available, i.e., 1948 to 2006. We propose that the portion of the knowledge in educational attainment delivered by the active workforce be considered as part...

  15. Occupational Therapy Evaluation for Stroke Adults in the United States

    Institute of Scientific and Technical Information of China (English)

    YANG Shan-li

    2010-01-01

    @@ Of the 700,000 people in the United States who experience a new or recurrent stroke each year, more than 500,000 survive(American Stroke Association, 2007)[1]. Occupational therapy practitioners are critical rehabilitation professionals for stroke survivors.

  16. Student Perceptions of Inclusion in Unit/Course Evaluations

    Science.gov (United States)

    Santhanam, Elizabeth; Hicks, Owen

    2004-01-01

    Good teaching should be inclusive of all students. There are very strong arguments for making courses/units/modules as inclusive as possible, based on issues of equity and access. Inclusive teaching has been a catch cry in recent times and most universities have policies related to this issue. However, research into the effectiveness of measures…

  17. Evaluation of four tax reforms in the United States

    DEFF Research Database (Denmark)

    Eissa, Nada; Kleven, Henrik Jacobsen; Kreiner, Claus Thustrup

    2008-01-01

    framework. We apply the framework to examine the welfare effects on single mothers in the United States following four tax acts passed in 1986, 1990, 1993, and 2001. We propose a simulation method combining features of fully structural microsimulation studies and simple deadweight loss calculations. Our...

  18. An Evaluation of United States Government Immigration Education Materials [and] Investigation of United States Immigration Education Correspondence Courses.

    Science.gov (United States)

    Nielson, Lynn E.

    An analysis of eight current government publications on citizenship for immigrants to the United States and results of a survey investigating immigration education correspondence courses are provided. In the first part, subjective evaluations of eight textbooks, based on seven designated criteria (copyright, readability, subject matter,…

  19. A new state evaluation method of oil pump unit based on AHP and FCE

    Science.gov (United States)

    Lin, Yang; Liang, Wei; Qiu, Zeyang; Zhang, Meng; Lu, Wenqing

    2017-05-01

    In order to make an accurate state evaluation of oil pump unit, a comprehensive evaluation index should be established. A multi-parameters state evaluation method of oil pump unit is proposed in this paper. The oil pump unit is analyzed by Failure Mode and Effect Analysis (FMEA), so evaluation index can be obtained based on FMEA conclusions. The weights of different parameters in evaluation index are discussed using Analytic Hierarchy Process (AHP) with expert experience. According to the evaluation index and the weight of each parameter, the state evaluation is carried out by Fuzzy Comprehensive Evaluation (FCE) and the state is divided into five levels depending on status value, which is inspired by human body health. In order to verify the effectiveness and feasibility of the proposed method, a state evaluation of oil pump used in a pump station is taken as an example.

  20. Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E).

    Science.gov (United States)

    Terszowski, Grzegorz; Waskow, Claudia; Conradt, Peter; Lenze, Dido; Koenigsmann, Jessica; Carstanjen, Dirk; Horak, Ivan; Rodewald, Hans-Reimer

    2005-03-01

    The erythrocyte colony-forming unit (CFU-E) is a rare bone marrow (BM) progenitor that generates erythrocyte colonies in 48 hours. The existence of CFU-Es is based on these colonies, but CFU-Es have not been purified prospectively by phenotype. We have separated the "nonstem," "nonlymphoid" compartment (lineage marker [lin]-c-Kit+Sca-1-IL-7Ralpha-) into interleukin 3 receptor alpha negative (IL-3Ralpha-) and IL-3Ralpha+ subsets. Within IL-3Ralpha- but not IL-3Ralpha+ cells we have identified TER119-CD41-CD71+ erythrocyte-committed progenitors (EPs). EPs generate CFU-E colonies at about 70% efficiency and generate reticulocytes in vivo. Depletion of EPs from BM strongly reduces CFU-E frequencies. EPs lack potential for erythrocyte burst-forming unit, megakaryocyte, granulocyte (G), and monocyte (M) colonies, and for spleen colony-forming units. Chronically suppressed erythropoiesis in interferon consensus sequence-binding protein (ICSBP)-deficient BM is associated with reduced frequencies of both the EP population and CFU-E colonies. During phenylhydrazine-induced acute anemia, numbers of both the EP population and CFU-E colonies increase. Collectively, EPs (lin-c-Kit+Sca-1-IL-7Ralpha-IL-3Ralpha-CD41-CD71+) account for most, if not all, CFU-E activity in BM. As a first molecular characterization, we have compared global gene expression in EPs and nonerythroid GM progenitors. These analyses define an erythroid progenitor-specific gene expression pattern. The prospective isolation of EPs is an important step to analyze physiologic and pathologic erythropoiesis.

  1. ON IDEAL CLASS GROUPS AND UNITS IN TERMS OF THE QUADRATIC FORM x2 + 32y2

    Institute of Scientific and Technical Information of China (English)

    JURGEN HURRELBRINK; YUE QIN

    2005-01-01

    For quadratic number fields F = Q(√2pl … pt-1 ) with primes pj ≡ 1 mod 8, the authors study the class number and the norm of the fundamental unit of F. The results generalize nicely what has been familiar for the fields Q(√2p) with a prime p ≡ 1 mod 8, including density statements. And the results are stated in terms of the quadratic form x2 + 32y2 and illustrated in terms of graphs.

  2. Total elbow arthroplasty in the United States: evaluation of cost, patient demographics, and complication rates

    Directory of Open Access Journals (Sweden)

    Hanbing Zhou

    2016-03-01

    Full Text Available Total elbow arthroplasty (TEA is utilized in the treatment of rheumatoid and post-traumatic elbow arthritis. TEA is a relatively low volume surgery in comparison to other types of arthroplasty and therefore little is known about current surgical utilization, patient demographics and complication rates in the United States. The purpose of our study is to evaluate the current practice trends and associated inpatient complications of TEA at academic centers in the United States. We queried the University Health Systems Consortium administrative database from 2007 to 2011 for patients who underwent an elective TEA. A descriptive analysis of demographics was performed which included patient age, sex, race, and insurance status. We also evaluated the following patient clinical benchmarks: hospital length of stay (LOS, hospital direct cost, inhospital mortality, complications, and 30-day readmission rates. Our cohort consisted of 3146 adult patients (36.5% male and 63.5% female with an average age of 58 years who underwent a total elbow arthroplasty (159 academic medical centers in the United States. The racial demographics included 2334 (74% Caucasian, 285 (9% black, 236 (7.5% Hispanic, 16 (0.5% Asian, and 283 (9% other patients. The mean LOS was 4.2±5 days and the mean total direct cost for the hospital was 16,300±4000 US Dollars per case. The overall inpatient complication rate was 3.1% and included mortality <1%, DVT (0.8%, re-operation (0.5%, and infection (0.4%. The 30-day readmission rate was 4.4%. TEA is a relatively uncommon surgery in comparison to other forms of arthroplasty but is associated with low in-patient and 30-day perioperative complication rate. Additionally, the 30-day readmission rate and overall hospital costs are comparable to the traditional total hip and knee arthroplasty surgeries.

  3. Evaluation of 3 dental unit waterline contamination testing methods

    OpenAIRE

    Porteous, Nuala; Sun, Yuyu; Schoolfield, John

    2015-01-01

    Previous studies have found inconsistent results from testing methods used to measure heterotrophic plate count (HPC) bacteria in dental unit waterline (DUWL) samples. This study used 63 samples to compare the results obtained from an in-office chairside method and 2 currently used commercial laboratory HPC methods (Standard Methods 9215C and 9215E). The results suggest that the Standard Method 9215E is not suitable for application to DUWL quality monitoring, due to the detection of limited n...

  4. Teaching Materials Evaluation and Adaptation of a Unit

    Institute of Scientific and Technical Information of China (English)

    沈化

    2014-01-01

    Teaching materials are quite important for teachers and students. Students only pay attention to interesting materials which can be counted good. Teachers should adapt the materials if they want to make the learning really take place and make their teaching more effective. The teaching materials in Unit 7 Weather in 21st Century Practical College English Viewing, Listen-ing&Speaking I can be counted good. But it is not good enough and needs adapting to make it better.

  5. Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients

    Directory of Open Access Journals (Sweden)

    Miguel Angel Arrabal-Polo

    Full Text Available ABSTRACT Introduction: The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness. Materials and Methods: This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed from June 2014 to May 2015. The patients were divided into two groups: Group 1 (single episode included 43 patients, and Group 2 (recurrent episodes included 36 patients. The density of six renal papillae (3 per kidney was measured, and the means obtained were compared between Groups 1 and 2. Statistical analysis was performed using SPSS 20.0. Results: The mean papillary density in Group 1 was 32.26 (SD 4.07 HU compared to 42.36 (SD 8.03 HU in Group 2 (P=00001. A ROC curve was constructed, obtaining an optimal cut-off point of 36.8HU [area under the curve, 0.881 (95% CI; 0.804-0.958; P=0001], with a sensitivity of 80% and a specificity of 90%. The relative risk was estimated at 40.3 (95% CI; 10.8-151.1, meaning that a patient with a mean papillary density greater than 36.8HU would have a 40 times greater risk of having recurrent renal stones. The positive predictive value (PPV was 81% and the negative predictive value (NPV was 90%. Conclusion: The measurement of renal papillary density could be useful in predicting recurrent stone-formers. These results need to be confirmed in future studies with a greater number of patients and a longer follow-up.

  6. Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients

    Science.gov (United States)

    Arrabal-Polo, Miguel Angel; Cano-Garcia, Maria del Carmen; Huerta-Brunel, Juan Esteban; Hidalgo-Agullo, Guillermo; Roletto-Salmo, Luis; Arrabal-Martín, Miguel

    2016-01-01

    ABSTRACT Introduction: The aim of this work is to study the density of the renal papillae in stone-forming patients and to determine its usefulness. Materials and Methods: This study included a total of 79 patients diagnosed with renal stones and on whom a computed tomography without contrast was performed from June 2014 to May 2015. The patients were divided into two groups: Group 1 (single episode) included 43 patients, and Group 2 (recurrent episodes) included 36 patients. The density of six renal papillae (3 per kidney) was measured, and the means obtained were compared between Groups 1 and 2. Statistical analysis was performed using SPSS 20.0. Results: The mean papillary density in Group 1 was 32.26 (SD 4.07) HU compared to 42.36 (SD 8.03) HU in Group 2 (P=00001). A ROC curve was constructed, obtaining an optimal cut-off point of 36.8HU [area under the curve, 0.881 (95% CI; 0.804-0.958); P=0001], with a sensitivity of 80% and a specificity of 90%. The relative risk was estimated at 40.3 (95% CI; 10.8-151.1), meaning that a patient with a mean papillary density greater than 36.8HU would have a 40 times greater risk of having recurrent renal stones. The positive predictive value (PPV) was 81% and the negative predictive value (NPV) was 90%. Conclusion: The measurement of renal papillary density could be useful in predicting recurrent stone-formers. These results need to be confirmed in future studies with a greater number of patients and a longer follow-up. PMID:27622277

  7. Activity of MKT 077, a rhodacyanine dye, against human tumor colony-forming units.

    Science.gov (United States)

    Petit, T; Izbicka, E; Lawrence, R A; Nalin, C; Weitman, S D; Von Hoff, D D

    1999-03-01

    MKT 077 is related to rhodamine 123 dye and demonstrates preferential accumulation in the mitochondria of cancer cells compared to normal cells. This difference in retention between cancer and normal cells led to the finding that MKT 077 selectively inhibits the growth of cancer cells in vitro. To define the preclinical activity profile of MKT 077, the compound was tested in vivo against a large variety of human tumors utilizing the human tumor-cloning assay. MKT 077 was studied using a sequential 2 h exposure separated by 24 h (2-24-2 h) and a 24 h exposure at final concentrations of 0.1, 0.2, 1.0, 2.0, 10.0 and 20.0 microg/ml. MKT 077 was also studied using continuous exposure at final concentrations of 0.1, 1.0 and 10 microg/ml. A decrease in tumor colony formation was considered significant if survival of colonies treated with MKT 077 was 50% or less compared to untreated controls. A total of 149 specimens was treated with MKT 077 with 51, 58 and 34 evaluable specimens with the 2-24-2 h, the 24 h and the continuous exposure, respectively. The results of the present study suggest a positive relationship between concentration and response. No relationship between exposure schedule and activity was observed. Inhibitory effects were obtained against multiple tumor types. High cytotoxic activity was obtained against breast, ovary, endometrial, colon and non-small cell lung cancer with concentrations of 2 microg/ml or above. In conclusion, the broad spectrum of cytotoxicity of MKT 077 in the human tumor-cloning assay and the unique mechanism of action of MKT 077 encourage additional preclinical and clinical studies with this compound and other rhodacyanine dyes.

  8. Organizational Analysis of the United States Army Evaluation Center

    Science.gov (United States)

    2014-12-01

    Separation Incentive Program (VSIP) as it appears as if all individuals on the same PD have the same exact skill mix .. The commodities that AEC evaluates...There is a varying mix of civilian and military personnel in all types of positions at AEC. Both types of personnel bring different but important...Report  OMAR  20  Safety Confirmation  SC  132  Safety Confirmation Recommendation  SCR   21  System Evaluation Plan  SEP  4  System Evaluation Plan

  9. Infertility Evaluation and Treatment among Women in the United States

    Science.gov (United States)

    Kessler, Lawrence M.; Craig, Benjamin M.; Plosker, Shayne M.; Reed, Damon R.; Quinn, Gwendolyn P.

    2013-01-01

    Objective To examine the characteristics of women seeking infertility evaluation and treatment. Design Cross-sectional survey based on in-person interviews, followed by two-step hurdle analysis. Participants 4,558 married or cohabitating women ages 25–44 Setting U.S. household population of women based on the 2006–2010 National Survey of Family Growth Intervention None Main Outcome Measure(s) Likelihood of seeking preliminary infertility evaluation. Likelihood of seeking infertility treatment once evaluated. Treatment type provided. Results 623 women (13.7%) reported seeking infertility evaluation, of which 328 reported undergoing subsequent infertility treatment. Age at marriage, marital status, education, health insurance status, race/ethnicity, and religion were associated with the likelihood of seeking infertility evaluation. For example, the predicted probability that a non-White woman who married at 25 will seek evaluation was 12%. This probability increased to 34% for White women with a graduate degree who married at age 30. Among women who are evaluated, income, employment status, and ethnicity correlated strongly with the likelihood of seeking infertility treatment. Infertility drug therapy was the most frequent treatment used. Reproductive surgery and in vitro fertilization (IVF) were used the least. Conclusions The use of infertility services is not random and understanding the socio-demographic factors correlated with use may assist new couples with family planning. Roughly 50% of the women evaluated for infertility progressed to treatment, and only a small proportion were treated with more advanced assisted reproductive technologies (ARTs) such as IVF therapy. Future research aimed at improving access to effective healthcare treatments within the boundaries of affordability is warranted. PMID:23849845

  10. An Evaluation of a Language for Paper-based Form Sketching

    DEFF Research Database (Denmark)

    Farruglia, Phillip; Borg, Johnathan; Camilleri, K.P.

    2006-01-01

    between paper-based form sketching and CAGM systems. Evaluation results revealed that whilst PSL is easy-to-learn, yet it requires improvements. Such a sketching language contributes a step towards simulating early form design solutions by the combined use of paper-based sketches and 3D models....... form idea. The research disclosed in this paper is aimed at combining the benefits of paper-based freehand sketches with those of three-dimensional (3D) models. More specifically, this paper reports the on-going development of a prescribed sketching language (PSL) required to create a seamless link...

  11. 76 FR 14678 - Communications Unit Leader Prerequisite and Evaluation

    Science.gov (United States)

    2011-03-17

    ... the entire collection increasing from the initial reported cost of $48,840 to $49,084. Analysis Agency... Burden Cost (operating/maintaining): $18,315. COML Train the Trainer Prerequisites Verification Frequency..., or other technological collection techniques or other forms of information technology, e.g...

  12. A copula-based closed-form binary logit choice model for accommodating spatial correlation across observational units

    Science.gov (United States)

    Bhat, Chandra R.; Sener, Ipek N.

    2009-09-01

    This study focuses on accommodating spatial dependency in data indexed by geographic location. In particular, the emphasis is on accommodating spatial error correlation across observational units in binary discrete choice models. We propose a copula-based approach to spatial dependence modeling based on a spatial logit structure rather than a spatial probit structure. In this approach, the dependence between the logistic error terms of different observational units is directly accommodated using a multivariate logistic distribution based on the Farlie-Gumbel-Morgenstein (FGM) copula. The approach represents a simple and powerful technique that results in a closed-form analytic expression for the joint probability of choice across observational units, and is straightforward to apply using a standard and direct maximum likelihood inference procedure. There is no simulation machinery involved, leading to substantial computation gains relative to current methods to address spatial correlation. The approach is applied to teenagers’ physical activity participation levels, a subject of considerable interest in the public health, transportation, sociology, and adolescence development fields. The results indicate that failing to accommodate heteroscedasticity and spatial correlation can lead to inconsistent and inefficient parameter estimates, as well as incorrect conclusions regarding the elasticity effects of exogenous variables.

  13. Evaluation of in-office dental unit waterline testing.

    Science.gov (United States)

    Momeni, Stephanie S; Tomline, Nancy; Ruby, John D; Dasanayake, Ananda P

    2012-01-01

    In-office dental unit waterline (DUWL) testing systems are commercially available for monitoring DUWL bacteria. The current study compared Aquasafe, Petrifilm, and Heterotrophic Plate Count Sampler (HPCS) with R2A plating methodology, considered the gold standard for enumerating heterotrophic bacteria in potable water. Samples were collected from 20 dental units. Heterotrophic bacterial counts of ≤500 CFUs/mL were used as the cut-off for assessing in-office testing compared to R2A laboratory plating. Validity was assessed using sensitivity and specificity, along with positive and negative predictive values. Results were also compared using concordance and kappa statistics. All in-office tests demonstrated 100% specificity and positive predictive values, while sensitivity and negative predictive values were low (Petrifilm, 57%/50%; HPCS, 50%/46%; Aquasafe, 21%/35%). Concordance and kappa values for agreement with R2A plating were as follows: Petrifilm 70% (κ = 0.44), HPCS 65% (κ = 0.38), and Aquasafe 45% (κ = 0.14). In-office DUWL testing with Aquasafe, Petrifilm, and HPCS agreed poorly with R2A plating methodology and is not valid or reliable as a means of accurately monitoring bacterial density in DUWL. These in-office test systems should not be used for assessing compliance with the ADA and CDC standard for acceptable heterotrophic bacterial counts in DUWLs (≤500 CFUs/mL).

  14. Evaluation of 3 dental unit waterline contamination testing methods.

    Science.gov (United States)

    Porteous, Nuala; Sun, Yuyu; Schoolfield, John

    2015-01-01

    Previous studies have found inconsistent results from testing methods used to measure heterotrophic plate count (HPC) bacteria in dental unit waterline (DUWL) samples. This study used 63 samples to compare the results obtained from an in-office chairside method and 2 currently used commercial laboratory HPC methods (Standard Methods 9215C and 9215E). The results suggest that the Standard Method 9215E is not suitable for application to DUWL quality monitoring, due to the detection of limited numbers of heterotrophic organisms at the required 35°C incubation temperature. The results also confirm that while the in-office chairside method is useful for DUWL quality monitoring, the Standard Method 9215C provided the most accurate results.

  15. Second law evaluation of a lightweight cooling unit

    Directory of Open Access Journals (Sweden)

    Guilherme B. Ribeiro

    2016-03-01

    Full Text Available The analysis based on the second law of thermodynamics of a lightweight vapor compression refrigeration system is presented. A small-scale linear compressor was applied in a DC-powered portable cooler for vehicles and for the medical field, using finned-tube heat exchangers and R600-a (Isobutane as the working fluid. The cooler was tested in an environmental chamber (with controlled temperature and humidity under three different ambient temperatures (21, 25 and 32 °C in order to measure key parameters of the system, such as cooling capacity, power consumption and internal air temperature. For the comparison of thermodynamic irreversibilities, a conventional vapor compression refrigerating system was also tested under the same ambient conditions. Results indicated that the system with the proposed lightweight system kept the lowest internal air temperature with higher coefficients of performance, showing how a lightweight cooling unit can enlarge the use of refrigerating systems due to its attributes.

  16. 78 FR 40760 - 60-Day Notice of Proposed Information Collection: Training Evaluation Form

    Science.gov (United States)

    2013-07-08

    ... URBAN DEVELOPMENT 60-Day Notice of Proposed Information Collection: Training Evaluation Form AGENCY... seeking approval from the Office of Management and Budget (OMB) for the information collection described... parties on the proposed collection of information. The purpose of this notice is to allow for 60 days...

  17. Syndrome dimensions of the Child Behavior Checklist and the Teacher Report Form : a critical empirical evaluation

    NARCIS (Netherlands)

    Hartman, CA; Hox, J; Auerbach, J; Erol, N; Fonseca, AC; Mellenbergh, GJ; Novik, TS; Oosterlaan, J; Roussos, AC; Shalev, RS; Zilber, N; Sergeant, JA

    1999-01-01

    The construct representation of the cross-informant model of the Child Behavior Checklist (CBCL) and the Teacher Report Form (TRF) was evaluated using confirmatory factor analysis. Samples were collected in seven different countries. The results are based on 13,226 parent ratings and 8893 teacher

  18. Syndrome dimensions of the Child Behavior Checklist and the Teacher Report Form : a critical empirical evaluation

    NARCIS (Netherlands)

    Hartman, CA; Hox, J; Auerbach, J; Erol, N; Fonseca, AC; Mellenbergh, GJ; Novik, TS; Oosterlaan, J; Roussos, AC; Shalev, RS; Zilber, N; Sergeant, JA

    1999-01-01

    The construct representation of the cross-informant model of the Child Behavior Checklist (CBCL) and the Teacher Report Form (TRF) was evaluated using confirmatory factor analysis. Samples were collected in seven different countries. The results are based on 13,226 parent ratings and 8893 teacher ra

  19. An Improved "Form of Our Own": A 21st Century Approach to School Librarian Evaluation

    Science.gov (United States)

    Owen, Patricia L.

    2011-01-01

    School librarians need evaluation forms that fit their unique roles and responsibilities and acknowledge both the similarities and differences between classroom teachers and school librarians. The incorporation of American Association of School Librarians' (AASL's) "Empowering Learners: Guidelines for School Library Programs"--a resource that sets…

  20. Criteria for Evaluating United States Marine Corps Installation Strategic Management

    Science.gov (United States)

    2001-12-01

    business success for the organization. The scoring weights emphasize those items identified in Marine Corps strategic documents as being of...should use this or a similar process to evaluate themselves. This system helps installations focus on keys to business success . If the Marine

  1. Quality evaluation of the Finasteride polymorphic forms I and II in capsules.

    Science.gov (United States)

    da Silva, Lucélia Magalhães; Montanari, Cristina Martiniano; Santos, Olimpia Maria Martins; Cazedey, Edith Cristina Laignier; Ângelo, Marilene Lopes; de Araújo, Magali Benjamin

    2015-02-01

    Finasteride (FNS) is a specific competitive inhibitor of steroid type-II 5α-reductase and is widely used for the treatment of benign prostatic hyperplasia, prostate cancer, and androgenetic alopecia. FNS has two polymorphic forms identified as Form I and Form II. It is known that polymorphism can cause significant differences in the physicochemical properties of a compound such as melting point, density, morphology, solubility, and color. Thus, proper qualitative and quantitative monitoring of the solid-state forms is crucial to ensure high-quality products. There are no published papers studying the influence of the FNS polymorphs on the physicochemical quality of capsules. Furthermore, the available analytical methods are time-consuming, expensive, use buffer or do not demonstrate stability-indicating capacity. The aim of this work was to validate a rapid high-performance liquid chromatography (HPLC) method to evaluate FNS in capsules and to study the physicochemical properties of polymorphic forms, evaluating their possible influence in the dissolution profile and stability of FNS in capsules. Capsules containing Forms I and II of FNS were prepared and subjected to quality control studies, dissolution profiles and a stability study at 50°C. A significant effect of polymorphism on the FNS solubility and dissolution properties was observed. These results suggest that changes in the effects of FNS can occur if a suitable control study is not performed on the raw material used to produce the capsules. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Perception Differences in Ambiguous Forms of Workplace Sexual Harassment: A Comparison between the United States and Turkey.

    Science.gov (United States)

    Toker, Yonca

    2016-07-03

    Certain social-sexual behaviors that could be potentially encountered in workplaces are ambiguous in nature and perceiving them as sexual harassment can depend on the culture. With an aim to delineate the overlap and distinctions of sexual harassment perceptions of such behaviors across samples of women university students from Turkey (TR, N = 215) and the United States (US, N = 209), measurement invariance and latent mean differences in perceiving three ambiguous forms; sexist hostility, sexual hostility, and insinuation-of-interest, were examined. It was hypothesized that the US sample would perceive sexist hostility more sexually harassing as sexist workplace discriminatory practices are emphasized as a form of sexual harassment, and that the TR sample would perceive sexual hostility and insinuation-of-interest as more sexually harassing as women in TR operate in a conservative context. Despite similarities in rank ordering, US participants perceived sexist hostility more sexually harassing; insinuation-of-interest and sexual hostility less sexually harassing than Turkish participants, supporting all three hypotheses. There are implications of differing perceptions across cultures for organizations in terms of disseminating awareness via training programs about the forms of sexual harassment (SH) in a local context and for taking account of local findings in shaping the labor code of countries in relation to SH.

  3. Thermal Environment Evaluation in Commercial Kitchens of United States

    DEFF Research Database (Denmark)

    Simone, Angela; Olesen, Bjarne W.

    The indoor climate in commercial kitchens is often unsatisfactory and the working conditions can have a significant effect on employees’ comfort and productivity. The differences between type (fast food, dining, etc.) and climatic zone can have an influence on the environment conditions and on th......The indoor climate in commercial kitchens is often unsatisfactory and the working conditions can have a significant effect on employees’ comfort and productivity. The differences between type (fast food, dining, etc.) and climatic zone can have an influence on the environment conditions...... and on the employees´ perception of kitchens thermal conditions. Moreover, size and arrangement of the kitchen zones, appliances, etc., complicate further an evaluation of the indoor thermal environment in kitchens. The on field physical measurements together with the occupants´ feedback is the effective way...... of defining the values of thermal comfort parameters in kitchens. It can also help to evaluate if the standardized methods are applicable for such non-uniform environment, like commercial kitchens. By using an established method and procedure for evaluating the indoor thermal comfort in commercial kitchens...

  4. A three-axis flight simulator. [for testing and evaluating inertial measuring units, and flight platforms

    Science.gov (United States)

    Mason, M. G.

    1975-01-01

    A simulator is described, which was designed for testing and evaluating inertial measuring units, and flight platforms. Mechanical and electrical specifications for the outer, middle, and inner axis are presented. Test results are included.

  5. Physical Unclonable Function with Multiplexing Units and its Evaluation

    Science.gov (United States)

    Yoshikawa, Masaya; Asai, Toshiya; Shiozaki, Mitsuru; Fujino, Takeshi

    Recently, semiconductor counterfeiting has become an increasingly serious problem. Therefore, techniques to prevent the counterfeit by using random characteristic patterns that are difficult to control artificially have attracted attention. The physical unclonable function (PUF) is one of the techniques. It is a method to derive ID information peculiar to a device by detecting random physical features that cannot be controlled during the device's manufacture. Because information such as the ID information is difficult to replicate, PUF is used as a technique to prevent counterfeiting. Several studies have been reported on PUF. Arbiter PUF, which utilizes the difference in signal propagation delay between selectors, is the typical method of composing PUF using delay characteristics. This paper proposed a new PUF which is based on the arbiter PUF. The proposed PUF introduces new multiplexing selector units. It attempts to generate an effective response using the orders of three signal arrivals. Experiments using FPGAs verify the validity of the proposed PUF. Although Uniqueness is deteriorated, Correctness, Steadiness, Randomness and Resistance against the machine learning attacks are improved in comparison with conventional one.

  6. 48 CFR 1553.209-70 - EPA Form 1900-26, Contracting Officer's Evaluation of Contractor Performance.

    Science.gov (United States)

    2010-10-01

    ..., Contracting Officer's Evaluation of Contractor Performance. 1553.209-70 Section 1553.209-70 Federal... 1553.209-70 EPA Form 1900-26, Contracting Officer's Evaluation of Contractor Performance. As prescribed... evaluation of Contractor performance....

  7. Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi

    Directory of Open Access Journals (Sweden)

    Sapi E

    2011-05-01

    Full Text Available Eva Sapi1, Navroop Kaur1, Samuel Anyanwu1, David F Luecke1, Akshita Datar1, Seema Patel1, Michael Rossi1, Raphael B Stricker21Lyme Disease Research Group, Department of Biology and Environmental Sciences, University of New Haven, New Haven, CT, USA; 2International Lyme and Associated Diseases Society, Bethesda, MD, USABackground: Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi. Although antibiotic therapy is usually effective early in the disease, relapse may occur when administration of antibiotics is discontinued. Studies have suggested that resistance and recurrence of Lyme disease might be due to formation of different morphological forms of B. burgdorferi, namely round bodies (cysts and biofilm-like colonies. Better understanding of the effect of antibiotics on all morphological forms of B. burgdorferi is therefore crucial to provide effective therapy for Lyme disease.Methods: Three morphological forms of B. burgdorferi (spirochetes, round bodies, and biofilm-like colonies were generated using novel culture methods. Minimum inhibitory concentration and minimum bactericidal concentration of five antimicrobial agents (doxycycline, amoxicillin, tigecycline, metronidazole, and tinidazole against spirochetal forms of B. burgdorferi were evaluated using the standard published microdilution technique. The susceptibility of spirochetal and round body forms to the antibiotics was then tested using fluorescent microscopy (BacLight™ viability staining and dark field microscopy (direct cell counting, and these results were compared with the microdilution technique. Qualitative and quantitative effects of the antibiotics against biofilm-like colonies were assessed using fluorescent microscopy and dark field microscopy, respectively.Results: Doxycycline reduced spirochetal structures ~90% but increased the number of round body forms about twofold. Amoxicillin reduced spirochetal forms by ~85%–90% and round body

  8. Evaluating flood potential with GRACE in the United States

    Science.gov (United States)

    Molodtsova, Tatiana; Molodtsov, Sergey; Kirilenko, Andrei; Zhang, Xiaodong; VanLooy, Jeffrey

    2016-04-01

    Reager and Famiglietti (2009) proposed an index, Reager's Flood Potential Index (RFPI), for early large-scale flood risk monitoring using the Terrestrial Water Storage Anomaly (TWSA) product derived from the Gravity Recovery and Climate Experiment (GRACE). We evaluated the efficacy of the RFPI for flood risk assessment over the continental USA using multi-year flood observation data from 2003 to 2012 by the US Geological Survey and Dartmouth Flood Observatory. In general, we found a good agreement between the RFPI flood risks and the observed floods on regional and even local scales. RFPI demonstrated skill in predicting the large-area, long-duration floods, especially during the summer season.

  9. Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species

    Science.gov (United States)

    Subburaj, Yamunadevi; Cosentino, Katia; Axmann, Markus; Pedrueza-Villalmanzo, Esteban; Hermann, Eduard; Bleicken, Stephanie; Spatz, Joachim; García-Sáez, Ana J.

    2015-08-01

    Bax is a key regulator of apoptosis that mediates the release of cytochrome c to the cytosol via oligomerization in the outer mitochondrial membrane before pore formation. However, the molecular mechanism of Bax assembly and regulation by other Bcl-2 members remains obscure. Here, by analysing the stoichiometry of Bax oligomers at the single-molecule level, we find that Bax binds to the membrane in a monomeric state and then self-assembles in Bax does not exist in a unique oligomeric state, but as several different species based on dimer units. Moreover, we show that cBid activates Bax without affecting its assembly, while Bcl-xL induces the dissociation of Bax oligomers. On the basis of our experimental data and theoretical modelling, we propose a new mechanism for the molecular pathway of Bax assembly to form the apoptotic pore.

  10. Evaluation of pentavalent rotavirus vaccination in neonatal intensive care units.

    Science.gov (United States)

    Thrall, Samuel; Doll, Margaret K; Nhan, Charles; Gonzales, Milagros; Perreault, Thérèse; Lamer, Philippe; Quach, Caroline

    2015-09-22

    Preterm infants are at highest risk for severe rotavirus gastroenteritis. While rotavirus vaccination is recommended for age-eligible, clinically stable preterm infants, controversy exists regarding vaccination of these infants during hospitalization. The objectives of this study were to examine tolerance of pentavalent rotavirus vaccination (RV5) among hospitalized infants and nosocomial rotavirus transmission in the neonatal intensive care units (NICU) at two urban hospitals. A retrospective, medical chart review of patients receiving RV5 vaccine was conducted to examine clinical histories of vaccine recipients. Average risk differences of gastrointestinal complications were estimated between the three days prior and up to four weeks following RV5 vaccination. A generalized linear regression model was used to examine the association between days since RV5 administration and daily feeding totals, using fixed effects to account for individual-level clustering. Rates of nosocomial rotavirus from active surveillance were compared between pre- and post-NICU-based vaccination periods. From July 1, 2011 to March 30, 2013, RV5 vaccination was initiated for 102 NICU patients. No changes in the average risk of gastrointestinal complications or daily feeding among participants overall were detected following RV5 administration. Rates of nosocomial rotavirus were similar during the periods before and after NICU-based vaccination. On average, RV5 appeared to be well tolerated among vaccine recipients, with no increase in nosocomial rotavirus transmission observed following NICU-based rotavirus vaccination. While the benefits of a RV5 NICU-based vaccination program for otherwise eligible preterm infants seem to outweigh the possible risk of vaccine virus transmission, further studies are needed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Evaluation of resistance form of different preparation features on mandibular molars

    Directory of Open Access Journals (Sweden)

    Bajoghli Farshad

    2013-01-01

    Full Text Available Aims: Resistance form of full metal-ceramic crown is an important feature that determines longevity of these restorations. This study evaluated the resistance form of full metal-ceramic prepared with four different design features. Materials and Methods: An acrylic tooth was prepared with 20° total occlusal convergence (TOC angle, 2.5 mm of occlusocervical dimension and a shoulder finishing line. This design lacked resistance form. The crown preparation was subsequently modified by preparing Mesial Occlusal Distal isthmus, placing occlusal inclined plane, and reducing TOC. Four metal dies from these designs were constructed by lathe machine and then 10 metal copings were fabricated for each preparation. Metal coping were cemented on metal dies with temp-bond cement. Force was applied at 45° from lingual to buccal direction with universal testing machine. Statistical analysis used: The data were evaluated by Kruskal-Wallis and non-parametric Mann-Whitney test. Results: All features increased resistance form when compare to control group. However, reduce TOC group showed greatest value of resistance. Conclusion: Within the limitation of this study, reducing the tapering of occlusocervival dimension is the most effective way in increasing resistance form, although, other features were also effective.

  12. An evaluation of teamwork within a specialist palliative care unit.

    Science.gov (United States)

    Donaghy, Kevin; Devlin, Breige

    2002-11-01

    This small-scale 10-month study evaluated teamworking within a specialist palliative care team. The study aims were to: collect, analyse and summarize information on how team members perceive teamworking; compare team members' perceptions after a teambuilding workshop; and to evaluate the longer term effect of this training on the team. A group of practitioners from a local Marie Curie Cancer Care Centre was selected and included members from all available disciplines. A piloted questionnaire was used to obtain qualitative and quantitative input. The team as a whole scored themselves above average on almost all counts. Following the teambuilding workshop significant improvement was seen in areas such as role appreciation and communication but not all improvements were long lasting. A perception of understaffing was noted as being one of the largest negative influences on teamwork whereas the setting and maintaining of agreed team objectives and having sufficient education opportunity were positive influences. Although teambuilding sessions appear to have the potential to produce the desired benefits, they should not be initiated at a time when staff already feel anxiety over their workload.

  13. ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.

    Science.gov (United States)

    Zhang, Lingbo; Prak, Lina; Rayon-Estrada, Violeta; Thiru, Prathapan; Flygare, Johan; Lim, Bing; Lodish, Harvey F

    2013-07-04

    Stem cells and progenitors in many lineages undergo self-renewing divisions, but the extracellular and intracellular proteins that regulate this process are largely unknown. Glucocorticoids stimulate red blood cell formation by promoting self-renewal of early burst-forming unit-erythroid (BFU-E) progenitors. Here we show that the RNA-binding protein ZFP36L2 is a transcriptional target of the glucocorticoid receptor (GR) in BFU-Es and is required for BFU-E self-renewal. ZFP36L2 is normally downregulated during erythroid differentiation from the BFU-E stage, but its expression is maintained by all tested GR agonists that stimulate BFU-E self-renewal, and the GR binds to several potential enhancer regions of ZFP36L2. Knockdown of ZFP36L2 in cultured BFU-E cells did not affect the rate of cell division but disrupted glucocorticoid-induced BFU-E self-renewal, and knockdown of ZFP36L2 in transplanted erythroid progenitors prevented expansion of erythroid lineage progenitors normally seen following induction of anaemia by phenylhydrazine treatment. ZFP36L2 preferentially binds to messenger RNAs that are induced or maintained at high expression levels during terminal erythroid differentiation and negatively regulates their expression levels. ZFP36L2 therefore functions as part of a molecular switch promoting BFU-E self-renewal and a subsequent increase in the total numbers of colony-forming unit-erythroid (CFU-E) progenitors and erythroid cells that are generated.

  14. Smile design and treatment planning with the help of a comprehensive esthetic evaluation form.

    Science.gov (United States)

    Calamia, John R; Levine, Jonathan B; Lipp, Mitchell; Cisneros, George; Wolff, Mark S

    2011-04-01

    Even if a clinician possesses basic knowledge in esthetic dentistry and clinical skills, many cases presenting in modern dental practices simply cannot be restored to both the clinician's and the patient's expectations without incorporating the perspectives and assistance of several dental disciplines. Besides listening carefully to chief complaints, clinicians must also be able to evaluate the patient's physical, biologic, and esthetic needs. This article demonstrates the use of a smile evaluation form designed at New York University that assists in developing esthetic treatment plans that might incorporate any and all dental specialties in a simple and organized fashion.

  15. Antioxidant activity evaluation of new dosage forms as vehicles for dehydrated vegetables.

    Science.gov (United States)

    Romero-de Soto, María Dolores; García-Salas, Patricia; Fernández-Arroyo, Salvador; Segura-Carretero, Antonio; Fernández-Campos, Francisco; Clares-Naveros, Beatriz

    2013-06-01

    A dehydrated vegetables mixture loaded in four pharmaceutical dosage forms as powder, effervescent granulate, sugar granulate and gumdrops were investigated for their antioxidant capacity using 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging capacity assay, oxygen radical absorbance capacity assay and ferric reducing antioxidant potential assay. Total phenolic content of dehydrated vegetables powder mixture was also measured by the Folin-Ciocalteu method, so as to evaluate its contribution to their total antioxidant function. The effect of different temperatures on stability of these systems after 90 days storage was also evaluated. These formulations presented strong antioxidant properties and high phenolic content (279 mg gallic acid equivalent/g of sample) and thus could be potential rich sources of natural antioxidants. Antioxidant properties differed significantly among selected formulations (p dosage forms are new and innovative approach for vegetable intakes in population with special requirements providing an improvement in the administration of vegetables and fruits.

  16. Research Note--Should Consumers Use the Halo to Form Product Evaluations?

    OpenAIRE

    Peter Boatwright; Ajay Kalra; Wei Zhang

    2008-01-01

    In purchase situations where attribute information is either missing or difficult to judge, a well-known heuristic that consumers use to form evaluations is the halo effect. The psychology literature has widely considered the halo a reflection of consumers' inability to discriminate between different attributes and have therefore labeled it the "halo error" or the "logical error." The objective of this paper is to offer a rationale for the halo effect. We use a decision-theory framework to sh...

  17. Evaluating the performance of university course units using data envelopment analysis

    Directory of Open Access Journals (Sweden)

    Sami El-Mahgary

    2014-12-01

    Full Text Available The technique of data envelopment analysis (DEA for measuring the relative efficiency has been widely used in the higher education sector. However, measuring the performance of a set of course units or modules that are part of a university curriculum has received little attention. In this article, DEA was used in a visual way to measure the performance of 12 course units that are part of a Photogrammetry curriculum taught at Aalto University. The results pinpointed the weakest performing units, i.e. units where the provided teaching efforts might not be adequately reflected in the students’ marks in the unit. Based on the results, a single unit was considered to offer poor performance with respect to its teaching resources and was selected as a candidate for revision of its contents. Financial resources were not used as such; instead, the performance of students in previous pre-requisite units was used as the inputs. For clarity, a single output covering the overall student performance in the examined unit was used. The technique should be widely applicable assuming the grade point averages of the students who took the course unit are available along with the marks obtained in the evaluated units and their pre-requisites.

  18. University-Based Evaluation Training Programs in the United States 1980-2008: An Empirical Examination

    Science.gov (United States)

    LaVelle, John M.; Donaldson, Stewart I.

    2010-01-01

    Evaluation practice has grown in leaps and bounds in recent years. In contrast, the most recent survey data suggest that there has been a sharp decline in the number and strength of preservice evaluation training programs in the United States. In an effort to further understand this curious trend, an alternative methodology was used to examine the…

  19. An Analysis of Grades, Class Level and Faculty Evaluation Scores in the United Arab Emirates

    Science.gov (United States)

    Waller, Lee

    2016-01-01

    This study examined the results of a student evaluation of faculty against the grades awarded and the level of the course for a higher education institution in the United Arab Emirates. The purpose of the study was to determine if the grades awarded in the course and/or level of the course impacted the evaluation scores awarded to the faculty…

  20. 48 CFR 1553.209-71 - EPA Form 1900-27, Project Officer's Evaluation of Contractor Performance.

    Science.gov (United States)

    2010-10-01

    ... Officer's Evaluation of Contractor Performance. 1553.209-71 Section 1553.209-71 Federal Acquisition... EPA Form 1900-27, Project Officer's Evaluation of Contractor Performance. As prescribed in 1509.170-4(a), EPA Form 1900-27 shall be used by the Project Officer to record his/her evaluation of...

  1. Pressurized thermal shock evaluation of the Calvert Cliffs Unit 1 Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, L [ed.

    1985-09-01

    An evaluation of the risk to the Calvert Cliffs Unit 1 nuclear power plant due to pressurized thermal shock (PTS) has been completed by Oak Ridge National Laboratory (ORNL) with the assistance of several other organizations. This evaluation was part of a Nuclear Regulatory Commission program designed to study the PTS risk to three nuclear plants, the other two plants being Oconee Unit 1 and H.B. Robinson Unit 2. The specific objectives of the program were to (1) provide a best estimate of the frequency of a through-the-wall crack in the pressure vessel at each of the three plants, together with the uncertainty in the estimated frequency and its sensitivity to the variables used in the evaluation; (2) determine the dominant overcooling sequences contributing to the estimated frequency and the associated failures in the plant systems or in operator actions; and (3) evaluate the effectiveness of potential corrective measures.

  2. Evaluation of the pneumatic tube system for transportation of packed red cell units

    Directory of Open Access Journals (Sweden)

    Supriya Dhar

    2015-01-01

    Full Text Available Background: Pneumatic tube system (PTS is commonly used in hospital settings to transport blood samples to diagnostic laboratories. At our blood center, we receive blood requisitions via the PTS, but units are carried to the ward by human courier. Recently we considered using the PTS for transporting blood units. Since, there are reports of hemolysis in blood samples sent through the PTS, we evaluated this system for transporting red cell units. Aims: The aim was to assess the effect of PTS transport on the quality of packed red cell units. Materials and Methods: A total of 50 red blood cells units (RBC, (25 non-irradiated and 25 irradiated were subjected to transportation through the PTS. The control arm in the study was age-matched RBC units not subjected to PTS transport. Each RBC unit was evaluated for hemoglobin (Hb, lactate dehydrogenase, potassium and plasma hemoglobin (Hb. The paired t-test was used to compare these parameters, and the P value was calculated. Results and Conclusion: The percentage of hemolysis after transportation through PTS was below the recommended guidelines. Delivery of the blood unit to the wrong station, bags lying unattended at the destination were few of the problems that had to be addressed. To conclude, though the PTS is a safe means of transporting blood products with reduction in the turn-around-time, it must be validated before use.

  3. Evaluation of Trapa bispinosa Roxb. starch as pharmaceutical binder in solid dosage form

    Institute of Scientific and Technical Information of China (English)

    Akhilesh V Singh; Anudwipa Singh; Lila K Nath; Nihar R Pani

    2011-01-01

    Objective: To evaluate binding efficiency of Trapa bispinosa Roxb. starch (TBS) in diclofenac sodium tablets. Methods: Diclofenac sodium tablets were prepared using wet granulation method. The starch paste in different concentrations (5%-15% w/w) was evaluated for optimized binder concentration. Preformulation study of the drug with TBS and different excipients were also analyzed using fourier transform infrared spectroscopy (FTIR) and isothermal stress testing (IST). Results: Preformulation study of the drug, water chestnut starch and different excipients showed no interaction or, drug degradation in FTIR and IST, respectively. The tablets were evaluated for hardness, friability, drug content, disintegration and dissolution studies, and all the parameters were found within the official specifications. Conclusions: The results reveal that this starch has potential to be used as binder at industrial scale in pharmaceutical solid dosage form development.

  4. Evaluation of forming limit in viscous pressure forming of automotive aluminum alloy 6k21-T4 sheet

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A ductile fracture criterion is introduced into numerical simulation to predict viscous pressure forming limit of the automotive body aluminum alloy 6k21-T4. The material constant in the ductile fracture criterion is determined by the combination of the viscous pressure bulging (VPB) test with numerical simulation. VPB tests of the aluminum alloy sheet are carried out by using various elliptical dies with different ratios of major axis to minor axis(β), and the bugling processes are simulated by the aid of the finite element method software LS-DYNA3D. On the basis of the stress and strain calculated from numerical simulations, the forming limits of bulging specimens obtained are predicted by the ductile fracture criterion, and compared with experimental results.The fracture initiation site and the minimal thickness predicted by the ductile fracture criterion are in good agreement with the experimental results.

  5. Carbon steel flanges and welds evaluation on HF-alkylation unit

    Energy Technology Data Exchange (ETDEWEB)

    Peiiuela, L.; Chirinos, J. [PDVSA Manufacture y Mercadeo, Judibana (Venezuela). Centro de Refinacion Paraguana

    1999-11-01

    In 1995, there were two failures in the 20,000 BPD HF Alky unit at the Amuay Refinery causing a shutdown of the unit. The failures occurred in one flange and one weld in the depropanizer charge carbon steel pipe, containing propane, isobutane and anhydrous hydrofluoric acid at 190 F (88 C) and 321psig (22.5 Kg/cm{sup 2}). Examination showed severe uniform corrosion at the inside surface of the flange while the adjacent elbow showed minimal corrosion loss. The other failure showed preferential attack in the weld without corrosion loss in the pipe components. A complete evaluation of the Alky plant was necessary to identify other lines in similar conditions that could cause future emergency shutdown of the unit. An extensive on stream inspection program was performed on critical lines of the unit. This paper summarizes the results and conclusions of this evaluation.

  6. Evaluating formability of LCP plate for sacral fractures with one step inverse forming finite element analysis.

    Science.gov (United States)

    Li, Xiaoda; Zhang, Xiangkui; Hu, Ping; Liu, Weijie; Shen, Guozhe; Zhan, Xianghui

    2015-01-01

    The locking compression plate fixation treatment for the unstable sacral fractures is simple and effective, with less trauma and complications. Some locking compression plate parts have been made of high-strength Plate manufactured by hot stamping process since the demand for lightweight biomedical materials. Finite Element (FE) method of One-Step inverse forming based on deformation theory is the tool to evaluate the formability of locking compression plate panel quickly in initial design for reducing costs and development cycle of Plate. But current one-step inverse forming methods are all suitable for cold stamping, not hot-stamping. This paper proposed one-step inverse forming method and workflow for hot-stamping of locking compression Plate. And the B pillar of a sacral bone was simulated and its computing result was compared with experimental value. The result shows that the proposed method in this paper can quickly evaluate high temperature formability of high-strength Plate. And the method is proposed to be used in initial design.

  7. Modeling the relationship between most probable number (MPN) and colony-forming unit (CFU) estimates of fecal coliform concentration.

    Science.gov (United States)

    Gronewold, Andrew D; Wolpert, Robert L

    2008-07-01

    Most probable number (MPN) and colony-forming-unit (CFU) estimates of fecal coliform bacteria concentration are common measures of water quality in coastal shellfish harvesting and recreational waters. Estimating procedures for MPN and CFU have intrinsic variability and are subject to additional uncertainty arising from minor variations in experimental protocol. It has been observed empirically that the standard multiple-tube fermentation (MTF) decimal dilution analysis MPN procedure is more variable than the membrane filtration CFU procedure, and that MTF-derived MPN estimates are somewhat higher on average than CFU estimates, on split samples from the same water bodies. We construct a probabilistic model that provides a clear theoretical explanation for the variability in, and discrepancy between, MPN and CFU measurements. We then compare our model to water quality samples analyzed using both MPN and CFU procedures, and find that the (often large) observed differences between MPN and CFU values for the same water body are well within the ranges predicted by our probabilistic model. Our results indicate that MPN and CFU intra-sample variability does not stem from human error or laboratory procedure variability, but is instead a simple consequence of the probabilistic basis for calculating the MPN. These results demonstrate how probabilistic models can be used to compare samples from different analytical procedures, and to determine whether transitions from one procedure to another are likely to cause a change in quality-based management decisions.

  8. Evaluation of heat stress in dry cleaner units:A case study in Qom, Iran

    Directory of Open Access Journals (Sweden)

    Javad Malakouti

    2016-04-01

    Full Text Available Background & Aims of the Study: Nowadays, heat stress is one of the most harmful physical agents in workplaces. According to the consequences of heat stress and have no information about it in Qom dry cleaner units, Iran, this study have been designed to evaluate the heat stress among workers of dry cleaner units in Qom province of Iran, in Jul-Aug 2011. Materials & Methods: This cross-sectional study was conducted in 113 units of active dry cleaner units. WBGT (Wet Bulb Globe Temperature index was selected for heat stress evaluation. In order to measure the requisite parameters, WBGT meter made of Casella Company had been used according to ISO 7243. Data had been analyzed according to Occupational Exposure Limits (OELs with SPSS V.16, using analysis of variance, independent T and LSD tests. Results: The average of WBGT index in Qom dry cleaner units of Iran were 28.98±1.64 °C. The average of WBGT index in 66.4% of units was up to 28°C. The average of relative humidity was 42.86%, the average of wet bulb temperature and globe temperature were 25.56°C and 36.72°C, respectively. The findings showed a significant correlation between the average of WBGT index and the standard recommendation level (p<0.0001. In dry cleaner units with less than 10 m2 area, heat stress was higher than other units  significantly (p<0.05. Conclusions: Heat stress in many dry cleaner units in Qom, Iran, was more than recommended OELs. Because of wet bulb and globe temperature in units were high value, the most important measures to heat controls, are technical engineering controls such as  radiation shield, insulation on boilers and modify the cooling systems.

  9. Artificial Neural Networks in Evaluation and Optimization of Modified Release Solid Dosage Forms

    Directory of Open Access Journals (Sweden)

    Zorica Djurić

    2012-10-01

    Full Text Available Implementation of the Quality by Design (QbD approach in pharmaceutical development has compelled researchers in the pharmaceutical industry to employ Design of Experiments (DoE as a statistical tool, in product development. Among all DoE techniques, response surface methodology (RSM is the one most frequently used. Progress of computer science has had an impact on pharmaceutical development as well. Simultaneous with the implementation of statistical methods, machine learning tools took an important place in drug formulation. Twenty years ago, the first papers describing application of artificial neural networks in optimization of modified release products appeared. Since then, a lot of work has been done towards implementation of new techniques, especially Artificial Neural Networks (ANN in modeling of production, drug release and drug stability of modified release solid dosage forms. The aim of this paper is to review artificial neural networks in evaluation and optimization of modified release solid dosage forms.

  10. Artificial neural networks in evaluation and optimization of modified release solid dosage forms.

    Science.gov (United States)

    Ibrić, Svetlana; Djuriš, Jelena; Parojčić, Jelena; Djurić, Zorica

    2012-10-18

    Implementation of the Quality by Design (QbD) approach in pharmaceutical development has compelled researchers in the pharmaceutical industry to employ Design of Experiments (DoE) as a statistical tool, in product development. Among all DoE techniques, response surface methodology (RSM) is the one most frequently used. Progress of computer science has had an impact on pharmaceutical development as well. Simultaneous with the implementation of statistical methods, machine learning tools took an important place in drug formulation. Twenty years ago, the first papers describing application of artificial neural networks in optimization of modified release products appeared. Since then, a lot of work has been done towards implementation of new techniques, especially Artificial Neural Networks (ANN) in modeling of production, drug release and drug stability of modified release solid dosage forms. The aim of this paper is to review artificial neural networks in evaluation and optimization of modified release solid dosage forms.

  11. Psychometric validation of the Brief Pain Inventory-Short Form in patients with systemic lupus erythematosus in the United States.

    Science.gov (United States)

    Naegeli, A N; Tomaszewski, E L; Al Sawah, S

    2015-11-01

    This study evaluated the Brief Pain Inventory-Short Form (BPI-SF) in patients with moderate-to-severe systemic lupus erythematosus (SLE). Patients ≥18 years old who self-reported a physician diagnosis of SLE (confirmed by medical record review) and active SLE (Systemic Lupus Activity Questionnaire (SLAQ) score of ≥11) were included. The BPI-SF and Short Form Health Survey version 2 (SF-36v2) were administered electronically at baseline, week 2 and week 12. Psychometric properties of the BPI-SF were evaluated. Cronbach alphas were >0.9 for all BPI-SF items, domains and total score. Test-retest reliability correlations for responses between baseline and week 2 of the BPI-SF had intraclass correlation coefficients (ICCs) ≥0.5. The BPI-SF domains and total score were moderately positively correlated to the SLAQ score (r ≥ 0.4), but negatively correlated to the SF-36v2 bodily pain domain (r ≤ -0.6). The BPI-SF domains and total score were moderately negatively correlated to the SF-36v2 physical functioning domain and physical component summary (r ≤ -0.4), with low correlations between the BPI-SF severity domain and SF-36v2 mental component summary (r = -0.16). Assessment of pain, as measured by the BPI-SF, demonstrated validity and reliability in a sample of patients with moderate-to-severe SLE. © The Author(s) 2015.

  12. Identifying and assessing strategies for evaluating the impact of mobile eye health units on health outcomes.

    Science.gov (United States)

    Fu, Shiwan; Turner, Angus; Tan, Irene; Muir, Josephine

    2017-08-14

    To identify and assess strategies for evaluating the impact of mobile eye health units on health outcomes. Systematic literature review. Worldwide. Peer-reviewed journal articles that included the use of a mobile eye health unit. Journal articles were included if outcome measures reflected an assessment of the impact of a mobile eye health unit on health outcomes. Six studies were identified with mobile services offering diabetic retinopathy screening (three studies), optometric services (two studies) and orthoptic services (one study). This review identified and assessed strategies in existing literature used to evaluate the impact of mobile eye health units on health outcomes. Studies included in this review used patient outcomes (i.e. disease detection, vision impairment, treatment compliance) and/or service delivery outcomes (i.e. cost per attendance, hospital transport use, inappropriate referrals, time from diabetic retinopathy photography to treatment) to evaluate the impact of mobile eye health units. Limitations include difficulty proving causation of specific outcome measures and the overall shortage of impact evaluation studies. Variation in geographical location, service population and nature of eye care providers limits broad application. © 2017 National Rural Health Alliance Inc.

  13. Evaluation of three percent Aqueous Film Forming Foam (AFFF) concentrates as fire fighting agents

    Science.gov (United States)

    Jablonski, E. J.

    1981-04-01

    A large-scale fire test program involving 20,000-square foot JP-4 fuel fires was conducted to evaluate the fire suppression effectiveness and compatibility of 3 percent Aqueous Film Forming Foam (AFFF) agents in Air Force fire fighting vehicles. Three commercially available 3 percent AFFF concentrates were tested in accordance with military specification MIL-F-24385B. Test results are summarized in Appendix A. As a result of these tests, an updated Revision C to this MIL SPEC has been accomplished with new requirements for both 3 percent and 6 percent AFFF extinguishing agents.

  14. Glass Forming Ability of Metallic Glasses Evaluated by a New Criterion

    Institute of Scientific and Technical Information of China (English)

    CAO Qing-Ping; LI Jin-Fu; ZHOU Yao-He

    2008-01-01

    The glass-forming ability (GFA) of Cu-Zr binary alloys is evaluated using the existing criteria based on calorimetric parameters, and poor relations are found. Therefore, another parameter Trk defined as Tk/Tl, in which Tk is the Kauzmann temperature and Tl the equilibrium liquidus temperature, is proposed. It exhibits good agreements with the experimental data of the Cu-Zr system and other representative bulk metallic glass formers so long as classifying them into strong or fragile category. It is suggested that kinetic effects are irrelevantly incorporated in the GFA analysis in the previous work.

  15. Risk assessment of human myelotoxicity of anticancer drugs: a predictive model and the in vitro colony forming unit granulocyte/macrophage (CFU-GM) assay.

    Science.gov (United States)

    Masubuchi, N

    2006-02-01

    Myelotoxicity is one of the major limitations to the use of anticancer drugs. It is desirable to evaluate human myelotoxicity before a Phase I study, however, this is difficult because of the differences in susceptibility between humans and animals. The purpose of this study was to establish a reliable method to predict the human maximum tolerated dose (MTD) of five camptothecin derivatives: SN-38, DX-8951f, topotecan (TPT), 9-aminocamptothecin (9-AC), and camptothecin (CAM). The myelotoxicity of camptothecin derivatives was evaluated on bone marrow from mice, dogs, and humans using a 14-day colony-forming unit-granulocyte/macrophage (CFU-GM) assay to determine the 50%, 75%, and 90% inhibitory concentration values (IC50, IC75, and IC90, respectively). Then, using human and murine IC90 values for myelotoxicity of these compounds, in vivo toxicological data, and pharmacokinetic parameters (data referred to the literature), human MTDs were predicted retrospectively. The mechanism-based prediction model which is proposed uses the in vitro CFU-GM assay and in vivo parameters on the basis of free fraction of area under the concentration-curve (AUC) at the MTD (r2 = 0.887) and suggests that the human MTDs were well predicted for the five camptothecin derivatives by this model rather than by other models. The application of this model for in vitro hematotoxicology could be very useful in the development of new anticancer agents.

  16. Social and Emotional Competencies Evaluation Questionnaire-Teacher's Version: Validation of a Short Form.

    Science.gov (United States)

    Coelho, Vitor A; Sousa, Vanda; Marchante, Marta

    2016-08-01

    The Social and Emotional Competencies Evaluation Questionnaire-Teacher's version, Short Form (QACSE-P-SF) allows teachers to assess their students' social and emotional competencies, having been designed for program evaluation. Thirty-nine teachers completed the QACSE-P-SF, regarding 657 students (fourth to ninth grades). Factor analyses supported a six-factor structure with acceptable internal consistency. Sex differences were found with teachers reporting girls as having higher scores on Self-Control, Social Awareness, Relationship Skills, and Responsible Decision Making. Developmental differences were also found with fourth-grade students presenting higher levels of Social Awareness and Relationship Skills than older students. The final version of the QACSE-P-SF is composed by 30 items, organized into six scales and less time consuming than the previous version for teachers who need to assess full classes.

  17. Psychometric evaluation and short form development of The Balanced Inventory of Desirable Responding (BIDR-6

    Directory of Open Access Journals (Sweden)

    Subotić Siniša

    2016-01-01

    Full Text Available The goals of this research were to evaluate the Bosnian-Croatian-Serbian (BCS translation of the BIDR-6 scale, develop its short form, and to present its initial convergent/discriminative validation. The sample included 827 participants. MIRT CFA analysis revealed that fourfactor model (containing 32/40 items fits the data best, with Self-Deceptive Enhancement (SDE and Impression Management (IM both splitting into the denial (SD-D and IM-D and enhancement (SD-E and IM-E factors. Fit and item properties were generally mediocre. SD-D and IM-E subscales were the strongest sources of misfit, thus SD-E and IM-D subscales were retained in the short form, which had good fit and replicated almost all main patterns of associations with other variables of interest (e.g., HEXACO personality traits typically reported for the full SDE and IM scales in other research. Thus, 17-item BIDR-6 short form, containing only SD-E and IM-D subscales, is recommended for use in the BCS speaking area.

  18. Evaluation of light curing units used for polymerization of orthodontic bonding agents.

    Science.gov (United States)

    Oyama, Nanako; Komori, Akira; Nakahara, Rizako

    2004-12-01

    This study evaluated the light intensity of various light curing units, the effect of distance of the light guide, and the validity of a tapered light guide. Light curing units tested included (1) four blue light-emitting diode curing units, Lux-O-Max, LEDemetronl, Ortholux LED, and The Cure; (2) two tungsten-quartz halogen curing units, Optilux 501 and Co-bee; and (3) one plasma arc curing unit, Apollo95E. The Optilux 501 was also evaluated for combinations of normal mode and boost mode and Standard tip and Turbo tip light guide. The spectral output of each unit was measured from 300 to 600 nm with a spectroradiometer. The light intensities at distances of zero, five, 10, 15, and 20 mm were determined with the radiometer. The peak value of Ortholux LED and The Cure surpassed that of Apollo95E. The light intensity significantly decreased with distance. Although The Cure showed a higher light intensity than the LEDemetron1 at zero-mm distance, the light intensity of the LEDemetron1 was higher than that of The Cure at five to 20 mm, resulting in no significant difference. The boost mode increased light intensity at any distance. Although the Turbo tip enhanced light intensity at zero-mm distance, reduction of light intensity by Turbo tip was demonstrated at five- to 20-mm distance.

  19. The reliability and validity of the American Board of Internal Medicine Monthly Evaluation Form.

    Science.gov (United States)

    Durning, Steven J; Cation, Lannie J; Jackson, Jeffrey L

    2003-11-01

    To report indicators of reliability and validity of the American Board of Internal Medicine Evaluation Form (ABIM-MEF) at one institution (Wright-Patterson Medical Center). Completed ABIM-MEFs from 1990-1999 were reviewed. Reliability measures included Cronbach alpha, interrater reliability, and rating consistency between different types of staff and rotations. Construct validity was investigated by tracking ABIM-MEF scores over time and with factor analysis. Predictive validity was assessed by correlating ABIM-MEF scores with the In-training Examination and ABIM Certifying Examination results The 71 residents averaged 12 ABIM-MEFs per year. The forms had a Cronbach alpha of 0.96 and high interrater reliability (intraclass correlation coefficients > 0.80). Ratings did not differ by type of attending or rotation, except that noninternists rated residents lower on procedural skills. ABIM-MEF questions about judgment, knowledge, and clinical skills showed significant improvement from month to month during each academic year as well as year to year. In contrast, questions on professional attitudes, humanism, and procedural skills sections improved between postgraduate year 1 and postgraduate year 2 only. ABIM-MEF questions collapsed into two domains in factor analysis: judgment-knowledge-skills and attitude-humanism. ABIM-MEF questions from judgment and knowledge sections modestly predicted In-training Examination and ABIM Certifying Examination results. In contrast, professional attitude, humanism, and clinical as well as procedural skill questions had little discriminative ability. The ABIM-MEF appears to be reliable and valid. Further, factor analysis results support the ABIM's movement to simplify the monthly evaluation form to the new Accreditation Council for Graduate Medical Education core competencies.

  20. Using rapid assessment to evaluate noise on an in-patient unit.

    Science.gov (United States)

    Deitrick, Lynn M; Kennedy, Paulette; Cyriax, Carol; Davies-Hathen, Nancy

    2009-01-01

    Rapid assessment was used to evaluate a noise problem on a busy, high-traffic, high-acuity medical/surgical telemetry unit over a 4-week period. Six sources of environmental noise were identified including conversational noise, noise from doors, noise from housekeeping activities, noise from the pneumatic message tube station, hallway noise, and miscellaneous noise. Our study also demonstrates the value of rapid-assessment methodology for the evaluation of clinical problems such as noise.

  1. Development and Test Evaluations for Ni-DOBDC Metal Organic Framework (MOF) Engineered Forms

    Energy Technology Data Exchange (ETDEWEB)

    Troy G. Garn; Mitchell Greenhalgh

    2013-07-01

    A joint effort to prepare engineered forms of a Ni-DOBDC metal organic framework (MOF) was completed with contributions from PNNL, SNL and the INL. Two independent methods were used at INL and SNL to prepare engineered form (EF) sorbents from Ni-DOBDC MOF powder developed and prepared at PNNL. Xe and Kr capacity test evaluations were performed at ambient temperature with the cryostat experimental setup at INL. The initial INL EF MOF test results indicated a Xe capacity of 1.6 mmol/kg sorbent and no Kr capacity. A large loss of surface area also occurred during minimal testing rendering the INL EF MOF unusable. Four capacity tests were completed using the SNL EF MOF at ambient temperature and resulted in Xe capacities of 1.4, 4.2, 5.0 and 3.8 mmol/kg sorbent with no Kr capacity observed in any ambient temperature tests. Two additional capacity tests were performed at 240 K to further evaluate SNL EF MOF performance. Xe capacities of 50.7 and 49.3 mmol/kg of sorbent and Kr capacities of 0.77 and 0.69 mmol/kg of sorbent were obtained, respectively. Following the adsorption evaluations, the SNL EF MOF material had lost about 40 % of the initial mass and 40 % of the initial surface area. In general, the Xe capacity results at ambient temperature for the INL and SNL EF Ni-DOBDC MOF’s were lower than 9.8 mmol Xe/kg sorbent test results reported by INL in FY-12 using PNNL’s inital EF supplied material.

  2. Evaluation of final waste forms and recommendations for baseline alternatives to group and glass

    Energy Technology Data Exchange (ETDEWEB)

    Bleier, A.

    1997-09-01

    An assessment of final waste forms was made as part of the Federal Facilities Compliance Agreement/Development, Demonstration, Testing, and Evaluation (FFCA/DDT&E) Program because supplemental waste-form technologies are needed for the hazardous, radioactive, and mixed wastes of concern to the Department of Energy and the problematic wastes on the Oak Ridge Reservation. The principal objective was to identify a primary waste-form candidate as an alternative to grout (cement) and glass. The effort principally comprised a literature search, the goal of which was to establish a knowledge base regarding four areas: (1) the waste-form technologies based on grout and glass, (2) candidate alternatives, (3) the wastes that need to be immobilized, and (4) the technical and regulatory constraints on the waste-from technologies. This report serves, in part, to meet this goal. Six families of materials emerged as relevant; inorganic, organic, vitrified, devitrified, ceramic, and metallic matrices. Multiple members of each family were assessed, emphasizing the materials-oriented factors and accounting for the fact that the two most prevalent types of wastes for the FFCA/DDT&E Program are aqueous liquids and inorganic sludges and solids. Presently, no individual matrix is sufficiently developed to permit its immediate implementation as a baseline alternative. Three thermoplastic materials, sulfur-polymer cement (inorganic), bitumen (organic), and polyethylene (organic), are the most technologically developed candidates. Each warrants further study, emphasizing the engineering and economic factors, but each also has limitations that regulate it to a status of short-term alternative. The crystallinity and flexible processing of sulfur provide sulfur-polymer cement with the highest potential for short-term success via encapsulation. Long-term immobilization demands chemical stabilization, which the thermoplastic matrices do not offer. Among the properties of the remaining

  3. Evaluation of the european heart failure self-care behaviour scale in a united kingdom population

    NARCIS (Netherlands)

    Shuldham, Caroline; Theaker, Chris; Jaarsma, Tiny; Cowie, Martin R.

    2007-01-01

    Title. Evaluation of the European Heart Failure Self-care Behaviour Scale in a United Kingdom population Aim. This paper is a report of a study to test the internal consistency, reliability and validity of the 12-item European Heart Failure Self-care Behaviour Scale in an English-speaking sample in

  4. Emergy Evaluation of Formal Education in the United States: 1870 to 2011

    Science.gov (United States)

    We evaluated the education system of the United States from 1870 to 2011 using emergy methods. The system was partitioned into three subsystems (elementary, secondary and college education) and the emergy inputs required to support each subsystem were determined for every year ov...

  5. Similar Demands, Different Responses: Teacher Evaluation in the United Kingdom and Singapore

    Science.gov (United States)

    Weinstein, Tracey L.; Struthers, Kathryn S.

    2012-01-01

    Using a conceptual framework grounded in globalization and the knowledge economy, this paper addresses teacher evaluation policy reform in the United Kingdom*** and Singapore. Specifically, the authors discuss similar demands faced by both countries: maintaining economic competitiveness in a globalized society, preparing citizens to participate in…

  6. Evaluation of the european heart failure self-care behaviour scale in a united kingdom population

    NARCIS (Netherlands)

    Shuldham, Caroline; Theaker, Chris; Jaarsma, Tiny; Cowie, Martin R.

    2007-01-01

    Title. Evaluation of the European Heart Failure Self-care Behaviour Scale in a United Kingdom population Aim. This paper is a report of a study to test the internal consistency, reliability and validity of the 12-item European Heart Failure Self-care Behaviour Scale in an English-speaking sample in

  7. Structural Evaluation of the Second Oldest Glued-Laminated Structure in the United States

    Science.gov (United States)

    Douglas R. Rammer; Jorge de Melo Moura

    2013-01-01

    The second glued-laminated structure built in the United States was constructed at the USDA Forest Products Laboratory (FPL) in 1934 to demonstrate the performance of wooden arch buildings. After decades of use the structure was decommissioned in 2010. Shortly after construction, researchers structurally evaluated the glued-laminated arch structure for uniform loading...

  8. The Development and Evaluation of the Multi-Unit Elementary School. Maxi II Practicum Report.

    Science.gov (United States)

    Durham, Joe D.

    The purpose of this practicum was to show the development and evaluation of a multi-unit elementary school (MUS-E) using Individually Guided Education. As an organizational structure capable of permitting planned change. MUS-E provides for the growth of its students on an individual basis, provides in-service for its teachers, involves the public…

  9. Ammonia concentration and bacterial evaluation of feline whole blood and packed red blood cell units stored for transfusion

    OpenAIRE

    Eva Spada; Daniela Proverbio; Piera Anna Martino; Luciana Baggiani; Roberta Perego; Nora Roggero

    2014-01-01

    Ammonia concentrations increase in human, canine and equine WB and PRBC units during storage. The aim of this study was to determine the effect of storage on ammonia concentration in feline WB and PRBC units stored in a veterinary blood bank and to evaluate possible correlations with bacterial contamination. Ammonia concentration was evaluated in 15 WB units and 2 PRBC units on day 1 and at the end of storage after 35 and 42 days, respectively. In an additional 5 WB units and 4 PRBC units amm...

  10. 75 FR 65700 - 60-Day Notice of Proposed Information Collection: R/PPR Evaluation and Measurement Unit...

    Science.gov (United States)

    2010-10-26

    ... Notice of Proposed Information Collection: R/PPR Evaluation and Measurement Unit, Evaluation Survey... of Information Collection: R/PPR Evaluation and Measurement Unit Survey Question Bank. OMB Control... Office of Management and Budget (OMB) approval for the information collection described below....

  11. Evaluation of electronic databases used to identify solid oral dosage forms.

    Science.gov (United States)

    Raschke, Carol G; Hatton, Randy C; Weaver, S Jay; Belgado, Bernadette S

    2003-09-01

    The ability of electronic drug identification databases to identify solid oral dosage forms by their imprint codes was studied. The following seven commercially available electronic drug identification databases were selected to identify 500 solid oral dosage forms by their imprint codes: Clinical Pharmacology (Gold Standard Media, Tampa, FL), eFacts (Facts and Comparison, St. Louis, MO), Ident-A-Drug (Therapeutic Research, Stockton, CA), Identidex (Micromedex, Greenwood Village, CO), Clinical Reference Library (Lexi-Comp, Hudson, OH), Physicians' Desk Reference (PDR) Electronic Library (Medical Economics, Montvale, NJ), and RxList (RxList LLC, San Francisco, CA), Chi-square test was used to compare the percentages of medications identified by each of the seven electronic references. The ability of the databases to identify medication by specific characteristics, such as brand name versus generic, prescription versus nonprescription, commercially available for more than one year versus less than one year, colored versus white drug products, and controlled versus noncontrolled substances was evaluated. A logistic regression model was used to determine the probability of a drug product being identified by one of the electronic references based on these characteristics. All seven electronic databases combined identified 95.6% of the unknown medications by imprint code, color, shape, and scoring. Ident-A-Drug and Identidex identified the most drugs. The PDR Electronic Library and Facts and Comparisons Identified the least number of drugs. Solid oral dosage forms more likely to be identified were those that were on the market for more than a year, brand-name products, and prescription medications. Generic products on the market for less than a year and nonprescription products were particularly difficult to identify. A combination of electronic drug identification databases provides the best method of drug identification in an institutional setting.

  12. Evaluation of medical devices in thoracic radiograms in intensive care unit - time to pay attention!

    Science.gov (United States)

    Moreira, Ana Sofia Linhares; Afonso, Maria da Graça Alves; Dinis, Mónica Ribeiro dos Santos Alves; dos Santos, Maria Cristina Granja Teixeira

    2016-01-01

    Objective To identify and evaluate the correct positioning of the most commonly used medical devices as visualized in thoracic radiograms of patients in the intensive care unit of our center. Methods A literature search was conducted for the criteria used to evaluate the correct positioning of medical devices on thoracic radiograms. All the thoracic radiograms performed in the intensive care unit of our center over an 18-month period were analyzed. All admissions in which at least one thoracic radiogram was performed in the intensive care unit and in which at least one medical device was identifiable in the thoracic radiogram were included. One radiogram per admission was selected for analysis. The radiograms were evaluated by an independent observer. Results Out of the 2,312 thoracic radiograms analyzed, 568 were included in this study. Several medical devices were identified, including monitoring leads, endotracheal and tracheostomy tubes, central venous catheters, pacemakers and prosthetic cardiac valves. Of the central venous catheters that were identified, 33.6% of the subclavian and 23.8% of the jugular were malpositioned. Of the endotracheal tubes, 19.9% were malpositioned, while all the tracheostomy tubes were correctly positioned. Conclusion Malpositioning of central venous catheters and endotracheal tubes is frequently identified in radiograms of patients in an intensive care unit. This is relevant because malpositioned devices may be related to adverse events. In future studies, an association between malpositioning and adverse events should be investigated. PMID:27737432

  13. Evaluation of fast neutron fluence for Kori Unit 2 pressure vessel

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Young Kyou; Lim, Mi Joung; Kim, Byoung Chul; Kim, Kyung Sik [Korea Reactor Integrity Surveillance Technology, Daejeon (Korea, Republic of)

    2011-10-15

    Unit 2 at Kori reactor has been put into operation in 1983. During 24 cycle operation, five surveillance capsules at inner vessel and three ex-vessel dosimeter at cavity both are taken out for evaluation to neutron fluence. The evaluations following the surveillance program of Kori 2 unit which are required detect and prevent degradation of safety-related structures and components of the vessel. The fast (E > 1.0 MeV) neutron fluencies are necessary to estimate the fracture toughness of the pressure vessel materials. The determination of the pressure vessel neutron fluence is based on both calculations and measurements. The fluence prediction is made with a calculation, and the measurements are used to qualify the calculational methodology. Measurement-to-calculation comparisons are used to identify biases in the calculations and to provide reliable estimates of the fluence uncertainties As shown in Fig. 1, the Kori unit 2 reactor vessel surveillance programs includes the analysis of flux dosimeters contained in capsules located on the inner vessel wall at the Beltline region (0., 15., 30. and 40. Azimuth) and Ex vessel dosimeter capsules located on the cavity at connected bid chain. In this paper, the methodologies used to perform neutron transport calculations and dosimetry evaluations are described, the results of the plant specific transport calculations are given for the beltline region of Kori Unit 2 pressure vessel and the comparisons of calculations and measurements are discussed

  14. Evaluation of syngas production unit cost of bio-gasification facility using regression analysis techniques

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Yangyang; Parajuli, Prem B.

    2011-08-10

    Evaluation of economic feasibility of a bio-gasification facility needs understanding of its unit cost under different production capacities. The objective of this study was to evaluate the unit cost of syngas production at capacities from 60 through 1800Nm 3/h using an economic model with three regression analysis techniques (simple regression, reciprocal regression, and log-log regression). The preliminary result of this study showed that reciprocal regression analysis technique had the best fit curve between per unit cost and production capacity, with sum of error squares (SES) lower than 0.001 and coefficient of determination of (R 2) 0.996. The regression analysis techniques determined the minimum unit cost of syngas production for micro-scale bio-gasification facilities of $0.052/Nm 3, under the capacity of 2,880 Nm 3/h. The results of this study suggest that to reduce cost, facilities should run at a high production capacity. In addition, the contribution of this technique could be the new categorical criterion to evaluate micro-scale bio-gasification facility from the perspective of economic analysis.

  15. Evaluation of vitamin D level in patients from neurosurgical intensive care unit

    Institute of Scientific and Technical Information of China (English)

    Ho Jun Yi; Je Hoon Jeong; Eun-Sun Jin; Il Young Shin; Hyung Sik Hwang; Seung-Myung Moon

    2013-01-01

    Vitamin D plays an important role in maintaining normal bone metabolism. Recent studies have suggested that vitamin D influences many other physiological processes, including muscle function, cardiovascular homeostasis, nerve function, and immune response. Furthermore, accumulated evidence suggests that vitamin D also mediates the immune system response to infection. Critical neurosurgical patients have higher infection and mortality rates. To correlate vitamin D deficiency to the immunological status of neurosurgical intensive care unit patients, we detected serum vitamin D level in 15 patients with clinically suspected infection and 10 patients with confirmed infection. Serum level of 25-hydroxyvitamin D, the primary circulating form of vitamin D, was significantly decreased in patients with suspected or confirmed infection after a 2-week neurosurgical intensive care unit hospitalization, while serum level of 1,25-dihydroxyvitamin D, the active form of vitamin D, was significantly decreased in patients after a 4-week neurosurgical intensive care unit hospitalization. These findings suggest that vitamin D deficiency is linked to the immunological status of neurosurgical intensive care unit patients and vitamin D supplementation can improve patient's immunological status.

  16. Self-Expanded Clustering Algorithm Based on Density Units with Evaluation Feedback Section

    Institute of Scientific and Technical Information of China (English)

    YU Yongqian; ZHAO Xiangguo; CHEN Hengyue; WANG Bin; YU Ge; WANG Guoren

    2006-01-01

    This paper presents an effective clustering mode and a novel clustering result evaluating mode. Clustering mode has two limited integral parameters. Evaluating mode evaluates clustering results and gives each a mark. The higher mark the clustering result gains, the higher quality it has. By organizing two modes in different ways, we can build two clustering algorithms: SECDU(Self-Expanded Clustering Algorithm based on Density Units) and SECDUF(Self-Expanded Clustering Algorithm Based on Density Units with Evaluation Feedback Section). SECDU enumerates all value pairs of two parameters of clustering mode to process data set repeatedly and evaluates every clustering result by evaluating mode. Then SECDU output the clustering result that has the highest evaluating mark among all the ones. By applying "hill-climbing algorithm", SECDUF improves clustering efficiency greatly. Data sets that have different distribution features can be well adapted to both algorithms. SECDU and SECDUF can output high-quality clustering results. SECDUF tunes parameters of clustering mode automatically and no man's action involves through the whole process. In addition, SECDUF has a high clustering performance.

  17. FORMULATION DEVELOPMENT AND EVALUATION OF CLARITHROMYCIN ORAL DOSAGE FORM AGAINST HELICOBACTER PYLORI INFECTION

    Directory of Open Access Journals (Sweden)

    Singh Pranjal Kumar

    2012-04-01

    Full Text Available There is keen interest in developing improved drug delivery systems to gastro intestinal tract for treatment of H. pylori induced peptic and duodenal ulcers, in the present study an attempt has been made to develop and evaluate gastroretentive matrix tablets of clarithromycin which were prepared by using Hydroxypropyl Methylcellulose K4M (HPMC K4M, Hydroxy Propyl Methyl Cellulose K15M (HPMC K15M and Hydroxypropyl Methylcellulose K100M (HPMC K100M with NaHCO3 as gas forming agent. Tablets were prepared by direct compression using directly compressible polymers such as HPMC K4M, HPMC K15M and HPMC K100M and were evaluated for drug - excipient compatibility, buoyancy test, tablet density, drug content and in-vitro release profile. Sodium bicarbonate was used for producing effervescent base for buoyancy of tablets. The release rate determined in 0.1 N HCL (pH 1.2 showed controlled release of drug following non-Fickian mechanism.

  18. FORMULATION AND EVALUATION OF ORAL CONTROLLED RELEASE DOSAGE FORM OF ANTI-HYPERTENSIVE AGENT

    Directory of Open Access Journals (Sweden)

    Lakshmi Parvathi A

    2012-12-01

    Full Text Available The aim of present investigation is preparation, characterization and evaluation of oral controlled release matrix tablets of Propranolol HCl in order to improve efficacy and to reduce the side effects. Tablets were prepared by direct compression method using different polymers like Guar gum, HPMC K4M, PVP and MCC used as the directly compressible vehicle. The granules were evaluated for pre-formulation characteristics and the tablets were subjected to post compression parameters, drug content and in-vitro dissolution release studies. In-vitro dissolution studies were carried out for 12 hrs and the results showed that among the nine formulations F8 and F9 showed good dissolution profile to control the drug release respectively. The drug release follows first order kinetics and the mechanism was found to be diffusion controlled for all the formulations (except F-9. The mechanism of drug release from F-9 was diffusion coupled with erosion. The Stability studies were carried out according to ICH guideline which indicates that the selected formulations (F8 and F9 were stable. In conclusion the results suggest that the developed matrix tablets of Propranolol HCl could perform therapeutically better than conventional dosage form, leading to improved efficacy and better patient compliance.

  19. Formulation and in vitro evaluation of sustained release dosage form with taste masking of metformin hydrochloride

    Directory of Open Access Journals (Sweden)

    Bhoyar P

    2010-01-01

    Full Text Available An attempt was made to sustain the release of metformin HCl as well as to mask the bitter taste by complexation technique using strong cation-exchange resins, indion 244 and indion 264. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, mode of mixing, ratio of drug:resin and temperature. The resinate was evaluated for micromeritic properties, taste masking and characterized using XRPD and IR. Using resinate sustained release tablets were formulated using hydoxypropylmethylcellulose K100M.The tablets were evaluated for hardness, thickness, friability, drug content, weight variation and in vitro drug release. Tablets thus formulated (Batch B-6 provided sustained release of drug over a period of 10 h with first order kinetics. The release of metformin HCl from resinate controls the diffusion of drug molecules through the polymeric material into aqueous medium. Results showed that metformin HCl was successfully taste masked and formulated into a sustained dosage form as an alternative to the conventional tablet.

  20. Wear rate evaluation of a novel polycarbonate-urethane cushion form bearing for artificial hip joints.

    Science.gov (United States)

    Elsner, Jonathan J; Mezape, Yoav; Hakshur, Keren; Shemesh, Maoz; Linder-Ganz, Eran; Shterling, Avi; Eliaz, Noam

    2010-12-01

    There is growing interest in the use of compliant materials as an alternative to hard bearing materials such as polyethylene, metal and ceramics in artificial joints. Cushion form bearings based on polycarbonate-urethane (PCU) mimic the natural synovial joint more closely by promoting fluid-film lubrication. In the current study, we used a physiological simulator to evaluate the wear characteristics of a compliant PCU acetabular buffer, coupled against a cobalt-chrome femoral head. The wear rate was evaluated over 8 million cycles gravimetrically, as well as by wear particle isolation using filtration and bio-ferrography (BF). The gravimetric and BF methods showed a wear rate of 9.9-12.5mg per million cycles, whereas filtration resulted in a lower wear rate of 5.8mg per million cycles. Bio-ferrography was proven to be an effective method for the determination of wear characteristics of the PCU acetabular buffer. Specifically, it was found to be more sensitive towards the detection of wear particles compared to the conventional filtration method, and less prone to environmental fluctuations than the gravimetric method. PCU demonstrated a low particle generation rate (1-5×10⁶ particles per million cycles), with the majority (96.6%) of wear particle mass lying above the biologically active range, 0.2-10μm. Thus, PCU offers a substantial advantage over traditional bearing materials, not only in its low wear rate, but also in its osteolytic potential.

  1. Formulation, development and evaluation of patient friendly dosage forms of metformin, Part-II: Oral soft gel

    Directory of Open Access Journals (Sweden)

    Mohapatra Ashutosh

    2008-01-01

    Full Text Available Dionvenience of administration and patient compliance are gaining significant importance in the design of dosage forms. Metformin hydrochloride is an orally administered antihyperglycemic agent, used in the management of non-insulin-dependant (type-2 diabetes mellitus. Difficulty in swallowing (dysphagia is common among all age groups, especially in elderly and pediatrics. Unfortunately, a high percentage of patients suffering from type-2 diabetes are elderly people showing dysphagia. Persons suffering from dysphagia may get choked when they consume liquid formulation, thus to alleviate such problem liquid formulation of high viscosity was prepared. Formulation of oral soft gel batches of metformin was carried out using hydrophilic polymer gellan gum at concentrations ranging from 0.2-0.4% w/v and sodium citrate at two different concentrations (0.3% and 0.5%. The prepared batches were evaluated for appearance, viscosity, pH, drug content, syneresis, in vitro drug release, and taste masking. The batch with 0.4% w/v gellan gum and 0.5% sodium citrate not only showed 85% drug release at 15 min, but all the desired organoleptic properties. The taste masking was carried out using nonnutritive sugar and flavors. The optimized batch showed substantial stability when subjected to short term stability study (0-8°C and Room temperature. The problem of dose measurement by patients was outweighed as oral medicated gels are to be packed in unit dose container.

  2. Residual stress evaluation and curvature behavior of aluminium 7050 peen forming processed; Avaliacao da tensao residual em aluminio 7050 conformado pelo processo peen forming

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, R.R. de; Lima, N.B., E-mail: rolivier@ipen.b, E-mail: nblima@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Braga, A.P.V.; Goncalves, M., E-mail: anapaola@ipt.b, E-mail: mgoncalves@ipt.b [Instituto de Pesquisas Tecnologicas (IPT), Sao Paulo, SP (Brazil)

    2010-07-01

    Shot peening is a superficial cold work process used to increase the fatigue life evaluated by residual stress measurements. The peen forming process is a variant of the shot peening process, where a curvature in the plate is obtained by the compression of the grains near to the surface. In this paper, the influence of the parameters such as: pressure of shot, ball shot size and thickness of aluminum 7050 samples with respect to residual stress profile and resulting arc height was studied. The evaluation of the residual stress profile was obtained by sin{sup 2} {Psi} method. (author)

  3. Evaluation of an interprofessional practice placement in a UK in-patient palliative care unit.

    Science.gov (United States)

    Dando, Nicholas; d'Avray, Lynda; Colman, Jane; Hoy, Andrew; Todd, Jennifer

    2012-03-01

    This paper reports on undergraduate students' evaluation of a new hospice-based interprofessional practice placement (IPP) that took place in the voluntary sector from 2008 to 2009. Ward-based interprofessional training has been successfully demonstrated in a range of clinical environments. However, the multidisciplinary setting within a hospice in-patient unit offered a new opportunity for interprofessional learning. The development and delivery of the IPP initiative is described, whereby multidisciplinary groups of 12 students provided hands-on care for a selected group of patients, under the supervision of trained health care professionals. The placement was positively evaluated and students reported an increased understanding of both their own role and that of other professionals in the team. The evaluation also suggests that additional learning opportunities were provided by the in-patient palliative care unit. The results of this evaluation suggest that the in-patient unit of a hospice caring for patients with life-limiting illness provides a suitable environment to demonstrate and learn about interprofessional practice.

  4. Evaluation of datum unit for diagnostics of journal-bearing systems

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Byung Chul; Jung, Joon Ha; Youn, Byeng Doog [Dept. of Mechanical and Aerospace Engineering, Seoul National University, Seoul (Korea, Republic of); Kim, Yeon Whan; Bae, Yong Chae [Power Generation Laboratory, KEPCO Research Institute, Daejeon (Korea, Republic of)

    2015-08-15

    Journal bearings support rotors using fluid film between the rotor and the stator. Generally, journal bearings are used in large rotor systems such as turbines in a power plant, because even in high-speed and load conditions, journal bearing systems run in a stable condition. To enhance the reliability of journal-bearing systems, in this paper, we study health-diagnosis algorithms that are based on the supervised learning method. Specifically, this paper focused on defining the unit of features, while other previous papers have focused on defining various features of vibration signals. We evaluate the features of various lengths or units on the separable ability basis. From our results, we find that one cycle datum in the time-domain and 60 cycle datum in the frequency domain are the optimal datum units for real-time journal-bearing diagnosis systems.

  5. Evaluation of various properties of alternative salt forms of sulfobutylether-beta-cyclodextrin, (SBE)7M-beta-CD.

    Science.gov (United States)

    Sotthivirat, S; Haslam, J L; Stella, V J

    2007-02-07

    The goal of this study was to evaluate alternative salt forms of (SBE)7M-beta-CD (currently the sodium salt). The potential salt form would ideally decrease the rate of (SBE)7M-beta-CD release from osmotic pump formulations and result in an increase in the rate and extent of drug release in osmotic pump tablet and pellet dosage forms. Several (SBE)7M-beta-CD salt forms (potassium, calcium, and two ethylene diamine salt forms) were prepared by either titration or ultrafiltration and characterized by elemental analysis and capillary electrophoresis, CE. The physical properties (water uptake behavior, osmolality, complexation characteristics, etc.) were then compared to the sodium salt form. Although the water isotherm and the binding characteristics using various model drugs were similar among all the salt forms, the calcium salt form appeared to be the best alternative candidate due to its lower osmolality and slower intrinsic dissolution rate.

  6. Evaluation and Verification of a Biological Shield in a SHARS Unit

    Energy Technology Data Exchange (ETDEWEB)

    Dhlomo, S.V.; Swart, H.S. [Compliance Management Department, Nuclear Liabilities Management, South African Nuclear Energy Corporation, P.O. Box 582, Pretoria 0001 (South Africa)

    2008-07-01

    The International Atomic Energy Agency (IAEA) Waste Technology Section with additional support from the U.S. National Nuclear Security Agency (NNSA) through the IAEA Nuclear Security Fund has funded the design, fabrication, evaluation, and testing of a portable hot cell intended to address the problem of disused SHARS in obsolete irradiation devices such as teletherapy heads and dry irradiators. This unit, designed and manufactured by the South African Nuclear Energy Corporation (Necsa), can be assembled, disassembled and packed inside two ISO containers and transported to the desired destination with relative ease. The unit was also licensed by the South African Regulator, the Department of Health (DoH), Directorate Radiation Control. This facility is used for the recovery and conditioning of orphaned/ abandoned or spent high activity radioactive sources from teletherapy units, gamma irradiators, and brachytherapy units. The hot cell was designed for a 3,7 E+13 Bq (1000 Ci) activity although it was demonstrated that it can handle activities of more than 7,4 E+13 Bq (2000 Ci) with ease. The biological shield of the SHARS facility consists of river sand sandwiched between metal plates, and a viewing window filled with a 50% zinc bromide solution. The shielding effectiveness of the river sand is evaluated experimentally by determining its density. The experimentally measured dose rates are compared to the dose rates estimated by computational codes. (authors)

  7. Evaluation of SPACE code for natural circulation test of Hanbit unit 2

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seyun; Kim, Minhee [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    SPACE (Safety and Performance Analysis Code for Nuclear Power Plants) has been developed by KHNP with the cooperation with KEPCO E and C and KAERI. SPACE code is expected to be applied to the safety analysis for LOCA (Loss of Coolant Accident) and Non-LOCA scenarios. SPACE code solves two-fluid, three-field governing equations and programmed with C++ computer language using object-oriented concepts. To evaluate the analysis capability for the passive cooling phenomenon in the actual nuclear power plant, a natural circulation test of Hanbit unit 2 was simulated with SPACE code. To evaluate the analysis capability for the passive cooling phenomenon in the actual nuclear power plant, a natural circulation test of Hanbit unit 2 was simulated with SPACE code. The major parameters of natural circulation in transient are well predicted in SPACE calculations when compared to the plant data. The SPACE code has sufficient capability to simulate passive cooling phenomena.

  8. Accelerated molecular dynamics force evaluation on graphics processing units for thermal conductivity calculations

    OpenAIRE

    Fan, Zheyong; Siro, Topi; Harju, Ari

    2012-01-01

    In this paper, we develop a highly efficient molecular dynamics code fully implemented on graphics processing units for thermal conductivity calculations using the Green-Kubo formula. We compare two different schemes for force evaluation, a previously used thread-scheme where a single thread is used for one particle and each thread calculates the total force for the corresponding particle, and a new block-scheme where a whole block is used for one particle and each thread in the block calcula...

  9. Emergy Evaluation of Formal Education in the United States: 1870 to 2011

    OpenAIRE

    2014-01-01

    We evaluated the education system of the United States from 1870 to 2011 using emergy methods. The system was partitioned into three subsystems (elementary, secondary and college/university education) and the emergy inputs required to support each subsystem were determined for every year over the period of analysis. We calculated the emergy required to produce an individual with a given number of years of education by summing over the years of support needed to attain that level of education....

  10. 76 FR 28303 - Requiring Residents Who Live Outside the United States To File Petitions According to Form...

    Science.gov (United States)

    2011-05-17

    ..., innovation, or the ability of United States-based companies to compete with foreign-based companies in... flexibility analysis is not required. This procedural rule will impact only individuals, not small entities as..., of $100 million or more in any one year, and it will not significantly or uniquely affect small...

  11. Initial Evaluation of Processing Methods for an Epsilon Metal Waste Form

    Energy Technology Data Exchange (ETDEWEB)

    Crum, Jarrod V.; Strachan, Denis M.; Zumhoff, Mac R.

    2012-06-11

    During irradiation of nuclear fuel in a reactor, the five metals, Mo, Pd, Rh, Ru, and Tc, migrate to the fuel grain boundaries and form small metal particles of an alloy known as epsilon metal ({var_epsilon}-metal). When the fuel is dissolved in a reprocessing plant, these metal particles remain behind with a residue - the undissolved solids (UDS). Some of these same metals that comprise this alloy that have not formed the alloy are dissolved into the aqueous stream. These metals limit the waste loading for a borosilicate glass that is being developed for the reprocessing wastes. Epsilon metal is being developed as a waste form for the noble metals from a number of waste streams in the aqueous reprocessing of used nuclear fuel (UNF) - (1) the {var_epsilon}-metal from the UDS, (2) soluble Tc (ion-exchanged), and (3) soluble noble metals (TRUEX raffinate). Separate immobilization of these metals has benefits other than allowing an increase in the glass waste loading. These materials are quite resistant to dissolution (corrosion) as evidenced by the fact that they survive the chemically aggressive conditions in the fuel dissolver. Remnants of {var_epsilon}-metal particles have survived in the geologically natural reactors found in Gabon, Africa, indicating that they have sufficient durability to survive for {approx} 2.5 billion years in a reducing geologic environment. Additionally, the {var_epsilon}-metal can be made without additives and incorporate sufficient foreign material (oxides) that are also present in the UDS. Although {var_epsilon}-metal is found in fuel and Gabon as small particles ({approx}10 {micro}m in diameter) and has survived intact, an ideal waste form is one in which the surface area is minimized. Therefore, the main effort in developing {var_epsilon}-metal as a waste form is to develop a process to consolidate the particles into a monolith. Individually, these metals have high melting points (2617 C for Mo to 1552 C for Pd) and the alloy is

  12. Rheology as a tool for evaluation of melt processability of innovative dosage forms.

    Science.gov (United States)

    Aho, Johanna; Boetker, Johan P; Baldursdottir, Stefania; Rantanen, Jukka

    2015-10-30

    Future manufacturing of pharmaceuticals will involve innovative use of polymeric excipients. Hot melt extrusion (HME) is an already established manufacturing technique and several products based on HME are on the market. Additionally, processing based on, e.g., HME or three dimensional (3D) printing, will have an increasingly important role when designing products for flexible dosing, since dosage forms based on compacting of a given powder mixture do not enable manufacturing of optimal pharmaceutical products for personalized treatments. The melt processability of polymers and API-polymer mixtures is highly dependent on the rheological properties of these systems, and rheological measurements should be considered as a more central part of the material characterization tool box when selecting suitable candidates for melt processing by, e.g., HME or 3D printing. The polymer processing industry offers established platforms, methods, and models for rheological characterization, and they can often be readily applied in the field of pharmaceutical manufacturing. Thoroughly measured and calculated rheological parameters together with thermal and mechanical material data are needed for the process simulations which are also becoming increasingly important. The authors aim to give an overview to the basics of rheology and summarize examples of the studies where rheology has been utilized in setting up or evaluating extrusion processes. Furthermore, examples of different experimental set-ups available for rheological measurements are presented, discussing each of their typical application area, advantages and limitations. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Evaluation of some organic compounds on bloodstream forms of Trypanosoma cruzi

    Directory of Open Access Journals (Sweden)

    João S. Silva

    1992-09-01

    Full Text Available Accidental transmission of Chagas' disease to man by blood transfusion is a serious problem in Latin-America. This paper describes the testing of several synthetic, semi-synthetic, and natural compounds for their activity against blood trypomastigotes in vitro at 4-C. The compounds embody several types of chemical structures: benzoquinone, naphthoquinone, anthracenequinone, phenanthrenequinone, imidazole, piperazine, quinoline, xanthene, and simple benzenic and naphthalenic derivates. Some of them are for the first time tested against Trypanosoma cruzi. The toxic effect these compounds on this parasite was done by two quite distinct sets of experiments. In one set, the compounds were added to infected blood as ethanolic solution. In this situation the most active one was a furan-1, 2-naphthoquinone, in the same range as gentian violet, a new fact to be considered in the assessment of structure-activity relationships in this class of compounds. In other set, we tentatively evaluated the biological activity of water insoluble compounds by adding them in a pure form without solvent into infected blood. In this way some appear to be very active and it was postulated that the effectiveness of such compounds must result from interactions between them and specific blood components.

  14. Evaluation of the Biocidal Efficacy of Different Forms of Silver Against Cupriavidus (formerly Wautersia) Species Bacteria

    Science.gov (United States)

    Gazda, Daniel B.; Schultz, John R.; Wong, Wing; Algate, Michelle T.; Bryant, Becky; Castro, Victoria A.

    2009-01-01

    Contingency Water Containers (CWCs) are used to store potable and technical water that is transferred to the International Space Station (ISS) from the Shuttle orbiter vehicles. When CWCs are filled, water from the orbiter galley is passed through an ion exchange/activated carbon cartridge that removes the residual iodine biocide used on Shuttle before silver biocide is added. Removal of iodine and addition of silver is necessary to inhibit microbial growth inside CWCs and maintain compatibility with the water systems in the Russian segment of ISS. As part of nominal water transfer activities, crewmembers collect samples from several CWCs for postflight analysis. Results from the analysis of water transfer samples collected during the docked phases of STS-118/13A.1 and STS-120/10A showed that several of the CWCs contained up to 10(exp 4) CFU/mL of bacteria despite the fact that the silver concentrations in the CWCs were within acceptable limits. The samples contained pure cultures of a single bacteria, a Cupriavidus (formerly Wautersia) species that has been shown to be resistant to metallic biocides. As part of the investigation into the cause and remediation of the bacterial contamination in these CWCs, ground studies were initiated to evaluate the resistance of the Cupriavidus species to the silver biocides used on ISS and to determine the minimum effective concentration for the different forms of silver present in the biocides. The initial findings from those experiments are discussed herein.

  15. In situ niosome forming maltodextrin proniosomes of candesartan cilexetil: In vitro and in vivo evaluations.

    Science.gov (United States)

    Yuksel, Nilufer; Bayindir, Zerrin Sezgin; Aksakal, Elif; Ozcelikay, A Tanju

    2016-01-01

    The aim of this study is to develop novel proniosomal tablets of candesartan cilexetil. Drug loaded proniosomes were prepared as dry powder by slurry method. The critical parameters of the production process were the type of the carrier (sorbitol, maltodextrin, and lactose), addition of charge inducers, rotation speed of the rotavapor and solvent evaporation temperature. The effects of these parameters on proniosome specifications such as the recovery, drug loading, drug release were investigated and also the influence on the particle size and surface charge of the niosomes derived by the hydration of proniosomes were evaluated. The mean particle size and drug loading of niosomes formed from the hydrated proniosomes were 204 ± 2 nm and 99.09 ± 0.04% respectively, with a negative charge -43.65 ± 0.54 mV. The proniosomes demonstrated good flowability, compressibility and consolidation properties both alone and together with the tableting agents (microcrystalline cellulose and cross-linked poly vinylpyrrolidone). The niosomes derived by the hydration of proniosomal tablets preserved their initial properties. Compatibly with the increased in vitro drug dissolution rate, the relative bioavailability of drug from proniosomal tablets increased 1.86-fold and 2.75-fold and higher candesartan plasma levels were achieved within shorter time compared to the pure drug.

  16. Preparation and evaluation of microcapsules using polymerized rosin as a novel wall forming material.

    Science.gov (United States)

    Fulzele, S V; Satturwar, P M; Kasliwal, R H; Dorle, A K

    2004-02-01

    Sustained release diclofenac sodium microcapsules were prepared using polymerized rosin as a novel wall-forming material by a solvent evaporation technique. A novel method developed in our laboratory with the potential for scale-up and production of polymerized rosin microcapsules is detailed. These microcapsules might have application for development of implant/depot systems, primarily due to a sustained/controlled release capability and potential biocompatibility of polymerized rosin. The effect of variables like solvent systems, stirring speed and temperature were previously optimized. The solution system of drug and polymerized rosin dissolved in iso-propyl alcohol and acetone is sprayed with the help of a 0.5 mm nozzle spray gun in liquid paraffin maintained at 60 degrees C in the stirring condition. Varying drug:polymer ratios, namely 1:1, 1:2, 2:1, 1:3 and 3:1, were employed for microcapsule preparation. The prepared microcapsules were evaluated for size, shape, drug content and in vitro drug release. The morphology of microcapsules was characterized by scanning electron microscopy. The microcapsules show sustained release curves at pH 7.4 phosphate buffer for up to 10 h. The data obtained from the dissolution profiles were compared in the light of different kinetics models and the regression coefficients were compared. The in vitro dissolution study confirmed the Higuchi-order release pattern. Particle size and release data analysis from five consecutive batches prepared in the laboratory indicated suitable reproducibility of the proposed solvent evaporation process.

  17. Evaluating the presence of Toxoplasma gondii in peripheral blood of patients with diverse forms of uveitis.

    Science.gov (United States)

    Belfort, Rubens N; Isenberg, Jordan; Fernandes, Bruno F; Di Cesare, Sebastian; Belfort, Rubens; Burnier, Miguel N

    2017-02-01

    The purpose of this study was to evaluate the presence of Toxoplasmosis gondii in samples of peripheral blood from patients with varying etiologies of uveitis. Whole blood from patients with different forms of uveitis was tested for the presence of T. gondii using real-time PCR targeting the well-characterized 529 bp fragment. Extracted DNA was both frozen. Thirty-one patients were included in the current study and grouped as follows: acute toxoplasmosis (n = 10); toxoplasmic retinal scars (n = 9); non-infectious etiologies of uveitis (n = 6); and IgG negative for toxoplasmosis (n = 6). In total, only two patients were shown to have circulating T. gondii in peripheral blood; both of these patients were IgG positive for toxoplasmosis, were receiving immunosuppressive therapy for autoimmune uveitis, and had no clinical features of toxoplasmosis. T. gondii was identified in peripheral blood of some immunosuppressed patients. No other patients, including those with acute toxoplasmosis, had circulating parasites in peripheral blood.

  18. Development of a method to evaluate shared alternate AC power source effects in multi-unit nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Woo Sik; Yang, Joon Eun

    2003-07-01

    In order to evaluate accurately a Station BlackOut (SBO) event frequency of a multi-unit nuclear power plant that has a shared Alternate AC (AAC) power source, an approach has been developed which accommodates the complex inter-unit behavior of the shared AAC power source under multi-unit Loss Of Offsite Power (LOOP) conditions. The approach is illustrated for two cases, 2 units and 4 units at a single site, and generalized for a multi-unit site. Furthermore, the SBO frequency of the first unit of the 2-unit site is quantified. The SBO frequency at a target unit of Probabilistic Safety Assessment (PSA) could be underestimated if the inter-unit dependency of the shared AAC power source is not properly modeled. The effect of the inter-unit behavior of the shared AAC power source on the SBO frequency is not negligible depending on the Common Cause Failure (CCF) characteristics among AC power sources. The methodology suggested in the present report is believed to be very useful in evaluating the SBO frequency and the core damage frequency resulting from the SBO event. This approach is also applicable to the probabilistic evaluation of the other shared systems in a multi-unit nuclear power plant.

  19. Evaluation of Suppression of Synthetic Paraffinic Kerosene (SPK) Fuel Fires with Aqueous Film Forming Foam (AFFF)

    Science.gov (United States)

    2009-12-01

    FIRES WITH AQUEOUS FILM FORMING FOAM ( AFFF ...performance of Aqueous Film-Forming Foam ( AFFF ) on synthetic fuel fires to aid Air Force firefighters’ response to an incident. Results show that AFFF can...hydrocarbons. Aqueous Film Forming Foam ( AFFF ) is used by Air Force fire departments to extinguish fuel spill fires involving jet fuel (JP-8), diesel,

  20. Evaluating Statistical Targets for Assembling Parallel Mixed-Format Test Forms

    Science.gov (United States)

    Debeer, Dries; Ali, Usama S.; van Rijn, Peter W.

    2017-01-01

    Test assembly is the process of selecting items from an item pool to form one or more new test forms. Often new test forms are constructed to be parallel with an existing (or an ideal) test. Within the context of item response theory, the test information function (TIF) or the test characteristic curve (TCC) are commonly used as statistical…

  1. Development and validation of evaluation tools of nursing students’ clinical pharmacology unit

    Science.gov (United States)

    Navabi, Nasrin; Ghaffari, Fatemeh; Shamsalinia, Abbas; Faghani, Safieh

    2016-01-01

    Introduction The need for valid, reliable, and objective tools has always been emphasized in studies related to the clinical assessment of nursing students. The aims of this study were to develop and assess the validity and reliability of the tools used to evaluate the clinical pharmacology unit. Methods This study was a methodological one, conducted in 2016. An item pool was developed based on the literature review and personal interviews with faculty members. The tool’s validity was determined through assessment of face validity, content validity, and construct validity, using exploratory factor analysis on the data provided by 264 second- and third-semester nursing students of the Islamic Azad University of Babol University of Medical Sciences. Reliability was determined through internal and external consistency, using a Cronbach’s coefficient of the correlation between classes. Results Based on the exploratory factor analysis, all items with a special value of >1 were grouped into six factors: 1) professional behavior; 2) effective communication; 3) recognition of medical terminology; 4) nursing actions before administering medicine; 5) nursing actions while administering medicine; and 6) nursing actions after administering medicine. These factors explained 77% of the total variance of the concept of assessment of the clinical pharmacology unit. In this study, reliability was demonstrated by a Cronbach’s alpha coefficient of 0.96; the correlation coefficient between floors for the total tool was 0.91, ranging from 0.64 to 0.89 in its dimensions. Conclusion The evaluation tool of the clinical pharmacology unit has an acceptable construct validity and satisfactory reliability and validity. Therefore, it can be used to evaluate the clinical pharmacology unit in the nursing education system in Iran. PMID:28008285

  2. Mechanical Properties of Ti-6Al-4V Octahedral Porous Material Unit Formed by Selective Laser Melting

    Directory of Open Access Journals (Sweden)

    Jianfeng Sun

    2012-01-01

    Full Text Available The Ti-6Al-4V octahedral porous material unit is designed to calculate its load. In this paper, ANSYS is adopted for the load simulation of the unit. And a simplified model of dimensional theoretical calculation is established, by which the analytical equation of the fracture load is obtained and the calculation of the load of Ti-6Al-4V is completed. Moreover, selective laser melting is adopted in processing the Ti-6Al-4V porous material unit. The experimental value of fracture load of this material is obtained through compression experiment. The results show that the simulation curves approximate the variation tendency of the elastic deformation of the compression curves; the curves of theoretical calculation approximate the general variation tendency; and the experimental value of fracture load is very close to the theoretical value. Therefore, the theoretical prediction accuracy of fracture load is high, which lays the foundation for the mechanical properties of the octahedral porous material.

  3. Evaluation of solid-state forms present in tablets by Raman spectroscopy.

    Science.gov (United States)

    Taylor, L S; Langkilde, F W

    2000-10-01

    In this study the potential of Fourier transform (FT)-Raman spectroscopy as a method to probe the solid-state form of active substances present in tablets and capsules is explored. Raman spectra were obtained from intact tablets and capsules containing enalapril maleate, prednisolone, form I and form II polymorphs of ranitidine, anhydrous and monohydrate theophylline, and warfarin sodium clathrate. Spectra were also collected from the corresponding drug substances. These studies show that it is possible to detect the active ingredients in the intact dosage form, even where the substance comprises tablet. Moreover, it is shown that, in some cases, Raman spectroscopy can also be used to investigate the solid-state form of a drug present in the dosage form and even to determine if a mixture of forms are present.

  4. Operational Evaluation of VEGGIE Food Production System in the Habitat Demonstration Unit

    Science.gov (United States)

    Stutte, Gary W.; Newsham, Gerard; Morrow, Robert M.; Wheeler, Raymond M.

    2011-01-01

    The 2010 Desert Research and Technology Studies (DRATS) of the VEGGIE Food Production System in the Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) was the first operational evaluation of salad crop production technology in a NASA analog test. A systematic evaluation of rooting media and nutrient delivery systems were evaluated for three lettuce cultivars that have shown promise as candidates for a surface based food production system. The VEGGIE nutrient delivery system worked well, was able to be maintained by multiple operators with a minimum of training, and supported excellent lettuce growth for the duration of the test. A Hazard Analysis and Critical Control Point (HACCP) evaluation was performed using ProSan(tm) as sanitation agent prior to consumption was approved, and the crew was allowed to consume the lettuce grown using the VEGGIE light cap and gravity based nutrient delivery system at the completion of the 14-day DRAT field test. The DRAT field test validated the crew operations; Growth of all lettuce cultivars was excellent. The operational DRAT field testing in the HDU identified light quality issues related to morphology and pigment development that will need to be addressed through additional testing. Feedback from the crew, ground support personnel, and human factors leads was uniformly positive on the psychological value of having the crop production system in the excursion module. A number of areas have been identified for future work, to minimize the "footprint" of the Food Production system through creative use of unused wall and floor space in the unit.

  5. Operation Evaluation of the VEGGIE Food Production System in the Habitat Demonstration Unit

    Science.gov (United States)

    Stutte, Gary W.; Newsham, Gerard; Morrow, Robert M.; Wheeler, Raymond M.

    2011-01-01

    The 2010 Desert Research and Technology Studies (DRATS) of the VEGGIE Food Production System in the Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) was the first operational evaluation of salad crop production technology in a NASA analog test. A systematic evaluation of rooting media and nutrient delivery systems were evaluated for three lettuce cultivars that have shown promise as candidates for a surface based food production system. The VEGGIE nutrient delivery system worked well, was able to be maintained by multiple operators with a minimum of training, and supported excellent lettuce growth for the duration of the test. A Hazard Analysis and Critical Control Point (HACCP) evaluation was performed using ProSantm as sanitation agent prior to consumption was approved, and the crew was allowed to consume the lettuce grown using the VEGGIE light cap and gravity based nutrient delivery system at the completion of the 14-day DRAT field test. The DRAT field test validated the crew operations; Growth of all lettuce cultivars was excellent. The operational DRAT field testing in the HDU identified light quality issues related to morphology and pigment development that will need to be addressed through additional testing. Feedback from the crew, ground support personnel, and human factors leads was uniformly positive on the psychological value of having the crop production system in the excursion module. A number of areas have been identified for future work, to minimize the "footprint" of the Food Production system through creative use of unused wall and floor space in the unit.

  6. Duration of temporary catheter use for hemodialysis: an observational, prospective evaluation of renal units in Brazil

    Directory of Open Access Journals (Sweden)

    Bonfante Gisele MS

    2011-11-01

    Full Text Available Abstract Background For chronic hemodialysis, the ideal permanent vascular access is the arteriovenous fistula (AVF. Temporary catheters should be reserved for acute dialysis needs. The AVF is associated with lower infection rates, better clinical results, and a higher quality of life and survival when compared to temporary catheters. In Brazil, the proportion of patients with temporary catheters for more than 3 months from the beginning of therapy is used as an evaluation of the quality of renal units. The aim of this study is to evaluate factors associated with the time between the beginning of hemodialysis with temporary catheters and the placement of the first arteriovenous fistula in Brazil. Methods This is an observational, prospective non-concurrent study using national administrative registries of all patients financed by the public health system who began renal replacement therapy (RRT between 2000 and 2004 in Brazil. Incident patients were eligible who had hemodialysis for the first time. Patients were excluded who: had hemodialysis reportedly started after the date of death (inconsistent database; were younger than 18 years old; had HIV; had no record of the first dialysis unit; and were dialyzed in units with less than twenty patients. To evaluate individual and renal unit factors associated with the event of interest, the frailty model was used (N = 55,589. Results Among the 23,824 patients (42.9% who underwent fistula placement in the period of the study, 18.2% maintained the temporary catheter for more than three months until the fistula creation. The analysis identified five statistically significant factors associated with longer time until first fistula: higher age (Hazard-risk - HR 0.99, 95% CI 0.99-1.00; having hypertension and cardiovascular diseases (HR 0.94, 95% CI 0.9-0.98 as the cause of chronic renal disease; residing in capitals cities (HR 0.92, 95% CI 0.9-0.95 and certain regions in Brazil - South (HR 0.83, 95% CI 0

  7. Duration of temporary catheter use for hemodialysis: an observational, prospective evaluation of renal units in Brazil.

    Science.gov (United States)

    Bonfante, Gisele M S; Gomes, Isabel C; Andrade, Eli Iola G; Lima, Eleonora M; Acurcio, Francisco A; Cherchiglia, Mariângela L

    2011-11-17

    For chronic hemodialysis, the ideal permanent vascular access is the arteriovenous fistula (AVF). Temporary catheters should be reserved for acute dialysis needs. The AVF is associated with lower infection rates, better clinical results, and a higher quality of life and survival when compared to temporary catheters. In Brazil, the proportion of patients with temporary catheters for more than 3 months from the beginning of therapy is used as an evaluation of the quality of renal units. The aim of this study is to evaluate factors associated with the time between the beginning of hemodialysis with temporary catheters and the placement of the first arteriovenous fistula in Brazil. This is an observational, prospective non-concurrent study using national administrative registries of all patients financed by the public health system who began renal replacement therapy (RRT) between 2000 and 2004 in Brazil. Incident patients were eligible who had hemodialysis for the first time. Patients were excluded who: had hemodialysis reportedly started after the date of death (inconsistent database); were younger than 18 years old; had HIV; had no record of the first dialysis unit; and were dialyzed in units with less than twenty patients. To evaluate individual and renal unit factors associated with the event of interest, the frailty model was used (N = 55,589). Among the 23,824 patients (42.9%) who underwent fistula placement in the period of the study, 18.2% maintained the temporary catheter for more than three months until the fistula creation. The analysis identified five statistically significant factors associated with longer time until first fistula: higher age (Hazard-risk - HR 0.99, 95% CI 0.99-1.00); having hypertension and cardiovascular diseases (HR 0.94, 95% CI 0.9-0.98) as the cause of chronic renal disease; residing in capitals cities (HR 0.92, 95% CI 0.9-0.95) and certain regions in Brazil - South (HR 0.83, 95% CI 0.8-0.87), Midwest (HR 0.88, 95% CI 0

  8. Ammonia concentration and bacterial evaluation of feline whole blood and packed red blood cell units stored for transfusion

    Directory of Open Access Journals (Sweden)

    Eva Spada

    2014-10-01

    Full Text Available Ammonia concentrations increase in human, canine and equine WB and PRBC units during storage. The aim of this study was to determine the effect of storage on ammonia concentration in feline WB and PRBC units stored in a veterinary blood bank and to evaluate possible correlations with bacterial contamination. Ammonia concentration was evaluated in 15 WB units and 2 PRBC units on day 1 and at the end of storage after 35 and 42 days, respectively. In an additional 5 WB units and 4 PRBC units ammonia concentrations were determined daily until the day the normal reference range was exceeded and then weekly to the end of storage. All units were evaluated for bacterial contamination. Ammonia increased markedly during storage as a linear function over time. On the 35th and 42th day of storage at 4±2°C mean±SD ammonia concentration reached 909±158 µg/dl and 1058±212 µg/dl in WB and PRBC units, respectively. Bacterial culture was negative in all units. High ammonia concentrations in stored WB and PRBC units could result in toxicity, particularly in feline recipients with liver failure, portosystemic shunts or those receiving large transfusion volumes. Clinical in vivo studies evaluating the effects on recipients should be performed.

  9. Evaluation and identification of histamine-forming bacteria on fish products of middle Adriatic Sea

    Directory of Open Access Journals (Sweden)

    Claudia Costanza

    2013-04-01

    Full Text Available Regulation EU 2073/2005 sets maximum concentration for histamine in fish and products thereof. To meet these criteria, manufacturers have to define performance objectives, such as the maximum allowed prevalence and number/activity of histamine-producing bacteria at relevant stage of production. In order to assess the presence and decarboxylase activity of contaminant bacteria we examined 51 samples of blue fish caught and processed in Emilia Romagna region. We collected 50 gr of fish (skin and gills or the entire product from 10 sample units from every lot. Analytical samples were cultured in Trypticase Soy Broth supplemented with histidine and pyridoxal HCl. Histamine was measured with an electrochemical biosensor after incubation at both 37°C for 24 h and 18-22°C for 48 h. Enrichments that showed relevant enzymatic activity were seeded on Niven agar to isolate suspected colonies and DNA extracts from these bacteria were analyzed by polymerase chain reaction (PCR for detecting specific sequences of the gene encoding pyridoxaldependent histidine decarboxylase (HDC. Overall, 29.4% samples showed relevant production of histamine in broth cultures (above a cut-off value set at 250 ng/mL and 53.3% of them (8 out of 15 samples allowed detection of HDC positive strains. All of them were typed as Morganella, which appears to be the most common of fish caught in middle Adriatic sea. Ten out of the twelve positive samples with enrichment cultures incubated at both 37 and 18-22°C (83% showed higher decarboxylase activity at room temperature, suggesting the presence of psychrotolerant strains. In addition, the prevalence of histamine-producing bacteria was higher at retail than at production level, probably as a consequence of manipulations and cross-contamination. The risk correlated to development of histamine-producing psychrotolerans bacteria cannot be controlled only with storage temperature: it is necessary for the food business operators to

  10. Performance evaluation of aprons according to lead equipment and form types

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki Won; Choi, Sung Hyun; Kim, Ki Yeol; Lee, Ik Pyo; Hwang, Sun Gwang [Dept. of Radiology, Kyung Hee University Hostpital at Gangdong, Seoul (Korea, Republic of); Dong, Kyung Rae [Dept. of of Radiological Technology, Gwangju Health University, Gwangju (Korea, Republic of)

    2017-02-15

    The apron is one of the essential protectors to reduce the exposure dose of radiological technologists. This study is to provide a guideline for purchasing the aprons with excellent performance and to help reducing the exposure dose by measuring the shielding ration and uniformity of aprons according to lead equivalent and form types. The shielding ratio of aprons were measured by using radiation generator and dosimeter. Exposure conditions were 81 kVp, 25 mAs, source to image receptor distance (SID) 100 cm and field of view (FOV) 17{sup ×}17{sup .} Exposure areas for front type and around type aprons were divided into 9 areas and for 2 pieces type aprons were divided into 3 areas of top and 4 areas of skirt. The uniformity of aprons were measured by using fluoroscopy and Image J. The 4 regions of interest (ROI) were set into acquired images and measured uniformity by measuring the standard deviation of pixel intensity in ROIs. In continuous shielding ration measurement of aprons according to exposure area, there was not statistical significance (P>0.05). In ANOVA test of aprons, there was statistical significance (P<0.01). In the results of shielding ratio, although the aprons had equal lead equivalent, there were difference in shielding ratio from 83.59% to 98.15%. In the results of uniformity, the front type aprons with equal lead equivalent indicated the similar uniformity. However, the around type and 2 pieces type apron with equal lead equivalent indicated the different uniformity each other, from 1.8 to 22.2. If the performance evaluation in this study were conducted regularly before and after purchase the aprons, the exposure does to patients and radiological technologists could be reduced.

  11. Evaluation of Cryotechniques for Tem Observation of Sols - Application to Boehmite Sols Used in Catalysts Forming

    Directory of Open Access Journals (Sweden)

    Fauchadour D.

    1999-07-01

    Full Text Available The use of suspensions in the heterogeneous catalysis field being a big issue, it appears important to be able to control this step as much as possible. Size of the objects in the suspension, aggregation state, homogeneity or heterogeneity (all called texture or structure here are some important parameters which are sometimes difficult to evaluate with traditionalmethods such as X-ray scattering or rheology. The cryotechniques applied to transmission electron microscopy is then an interesting alternative. Three different methods of cryofixation have been tested on low solid content suspensions of boehmite commonly used during the dispersion step of alumina carrier forming. Two different cryoprotectants were tested as well. It is shown that liquid propane immersion cooling (PL and slam freezing (SF methods require the use of a cryoprotectant whereas high pressure technique (HP avoids ice crystal formation without any addition of cryoprotectant in the suspension. It is shown also that DMSO is efficient with PL and SF techniques only when added at a high concentration (50% to the suspension. Glycerol is preferred because water is vitrified since that 30% of glycerol is added. Comparisons of high pressure preparations with and without glycerol show very little differences of texture on the replica. Explanations of the origin of the small differences of density are tentatively given. More analyses are now under progress to clarify the role of glycerol. Cryomicroscopy is conclude to be a very good technique when the texture of a suspension must be studied for example in the elaboration or in the improvement of a peptisation or a colloid formation process.

  12. Geochemical and geostatistical evaluation, Arkansas Canyon Planning Unit, Fremont and Custer Counties, Colorado

    Science.gov (United States)

    Weiland, E.F.; Connors, R.A.; Robinson, M.L.; Lindemann, J.W.; Meyer, W.T.

    1982-01-01

    A mineral assessment of the Arkansas Canyon Planning Unit was undertaken by Barringer Resources Inc., under the terms of contract YA-553-CTO-100 with the Bureau of Land Management, Colorado State Office. The study was based on a geochemical-geostatistical survey in which 700 stream sediment samples were collected and analyzed for 25 elements. Geochemical results were interpreted by statistical processing which included factor, discriminant, multiple regression and characteristic analysis. The major deposit types evaluated were massive sulfide-base metal, sedimentary and magmatic uranium, thorium vein, magmatic segregation, and carbonatite related deposits. Results of the single element data and multivariate geostatistical analysis indicate that limited potential exists for base metal mineralization near the Horseshoe, El Plomo, and Green Mountain Mines. Thirty areas are considered to be anomalous with regard to one or more of the geochemical parameters evaluated during this study. The evaluation of carbonatite related mineralization was restricted due to the lack of geochemical data specific to this environment.

  13. Evaluation of electromagnetic interference environment of the instrumentation and control systems in nuclear power units

    Energy Technology Data Exchange (ETDEWEB)

    Min, Moon-Gi; Lee, Jae-Ki; Ji, Yeong-Haw; Jo, Sung-Han [Korea Hydro & Nuclear Power Co., Ltd., 1312-70 Yuesong-daero, Yuseong-Gu, Daejeon 305-343 (Korea, Republic of); Kim, Hee-Je, E-mail: heeje@pusan.ac.kr [Pusan National University, 2, Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 609-735 (Korea, Republic of)

    2015-04-15

    Highlights: • We surveyed the electromagnetic emissions at the location of I&C systems. • We assessed the electromagnetic levels on reactor types from thirteen nuclear plants. • We evaluated the margin between plant emission limits and the highest composite levels. • We presented the formula of radiated susceptibility test levels to non-safety-related I&C systems. - Abstract: The electromagnetic interference (EMI) generated from sources in power units can interfere with digital Instrument and Control (I&C) systems. When EMI is emitted with conducted and radiated noise, it interferes with the signals of the I&C systems. Since the digital I&C systems are efficient and competitively priced, the analogue I&C systems have been upgraded and replaced with digital I&C systems, but these systems have less EMI immunity. When safety-related I&C systems are installed in the units, the verification of equipment EMI should not be done in site-specific tests but in test facilities. There are needs to do the overall site-specific EMI assessment of I&C systems depending on the reactor types from thirteen operating units. This study evaluated the margin between plant emission limits and the highest composite plant emissions of the EMI. When the non-safety-related I&C equipment or systems are placed in the units, there are no individual test levels of the radiated electrical field. If need be, the level should comply with the test levels of the radiated electrical field on the safety-related I&C systems. This paper presents the test levels of radiated electrical fields to non-safety-related I&C equipment or systems.

  14. EVALUATION OF THOR MINERALIZED WASTE FORMS FOR THE DOE ADVANCED REMEDIATION TECHNOLOGIES PHASE 2 PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, C.; Jantzen, C.

    2012-02-02

    , sulfates/sulfides, chlorides, fluorides, volatile radionuclides or other aqueous components. The FBSR technology can process these wastes into a crystalline ceramic (mineral) waste form. The mineral waste form that is produced by co-processing waste with kaolin clay in an FBSR process has been shown to be as durable as LAW glass. Monolithing of the granular FBSR product, which is one of the objectives of this current study, is being investigated to prevent dispersion during transport or burial/storage but is not necessary for performance. FBSR testing of a Hanford LAW simulant and a WTP-SW simulant at the pilot scale was performed by THOR Treatment Technologies, LLC at Hazen Research Inc. in April/May 2008. The Hanford LAW simulant was the Rassat 68 tank blend and the target concentrations for the LAW was increased by a factor of 10 for Sb, As, Ag, Cd, and Tl; 100 for Ba and Re (Tc surrogate); 1,000 for I; and 254,902 for Cs based on discussions with the DOE field office and the environmental regulators and an evaluation of the Hanford Tank Waste Envelopes A, B, and C. It was determined through the evaluation of the actual tank waste metals concentrations that some metal levels were not sufficient to achieve reliable detection in the off-gas sampling. Therefore, the identified metals concentrations were increased in the Rassat simulant processed by TTT at HRI to ensure detection and enable calculation of system removal efficiencies, product retention efficiencies, and mass balance closure without regard to potential results of those determinations or impacts on product durability response such as Toxicity Characteristic Leach Procedure (TCLP). A WTP-SW simulant based on melter off-gas analyses from Vitreous State Laboratory (VSL) was also tested at HRI in the 15-inch diameter Engineering Scale Test Demonstration (ESTD) dual reformer at HRI in 2008. The target concentrations for the Resource Conservation and Recovery Act (RCRA) metals were increased by 16X for Se, 29X for

  15. EVALUATION OF THOR MINERALIZED WASTE FORMS FOR THE DOE ADVANCED REMEDIATION TECHNOLOGIES PHASE 2 PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, C.; Jantzen, C.

    2012-02-02

    , sulfates/sulfides, chlorides, fluorides, volatile radionuclides or other aqueous components. The FBSR technology can process these wastes into a crystalline ceramic (mineral) waste form. The mineral waste form that is produced by co-processing waste with kaolin clay in an FBSR process has been shown to be as durable as LAW glass. Monolithing of the granular FBSR product, which is one of the objectives of this current study, is being investigated to prevent dispersion during transport or burial/storage but is not necessary for performance. FBSR testing of a Hanford LAW simulant and a WTP-SW simulant at the pilot scale was performed by THOR Treatment Technologies, LLC at Hazen Research Inc. in April/May 2008. The Hanford LAW simulant was the Rassat 68 tank blend and the target concentrations for the LAW was increased by a factor of 10 for Sb, As, Ag, Cd, and Tl; 100 for Ba and Re (Tc surrogate); 1,000 for I; and 254,902 for Cs based on discussions with the DOE field office and the environmental regulators and an evaluation of the Hanford Tank Waste Envelopes A, B, and C. It was determined through the evaluation of the actual tank waste metals concentrations that some metal levels were not sufficient to achieve reliable detection in the off-gas sampling. Therefore, the identified metals concentrations were increased in the Rassat simulant processed by TTT at HRI to ensure detection and enable calculation of system removal efficiencies, product retention efficiencies, and mass balance closure without regard to potential results of those determinations or impacts on product durability response such as Toxicity Characteristic Leach Procedure (TCLP). A WTP-SW simulant based on melter off-gas analyses from Vitreous State Laboratory (VSL) was also tested at HRI in the 15-inch diameter Engineering Scale Test Demonstration (ESTD) dual reformer at HRI in 2008. The target concentrations for the Resource Conservation and Recovery Act (RCRA) metals were increased by 16X for Se, 29X for

  16. Student Personality Differences Are Related to Their Responses on Instructor Evaluation Forms

    Science.gov (United States)

    McCann, Stewart; Gardner, Christopher

    2014-01-01

    The relation of student personality to student evaluations of teaching (SETs) was determined in a sample of 144 undergraduates. Student Big Five personality variables and core self-evaluation (CSE) were assessed. Students rated their most preferred instructor (MPI) and least preferred instructor (LPI) on 11 common evaluation items. Pearson and…

  17. Annotated corpus and the empirical evaluation of probability estimates of grammatical forms

    Directory of Open Access Journals (Sweden)

    Ševa Nada

    2003-01-01

    Full Text Available The aim of the present study is to demonstrate the usage of an annotated corpus in the field of experimental psycholinguistics. Specifically, we demonstrate how the manually annotated Corpus of Serbian Language (Kostić, Đ. 2001 can be used for probability estimates of grammatical forms, which allow the control of independent variables in psycholinguistic experiments. We address the issue of processing Serbian inflected forms within two subparadigms of feminine nouns. In regression analysis, almost all processing variability of inflected forms has been accounted for by the amount of information (i.e. bits carried by the presented forms. In spite of the fact that probability distributions of inflected forms for the two paradigms differ, it was shown that the best prediction of processing variability is obtained by the probabilities derived from the predominant subparadigm which encompasses about 80% of feminine nouns. The relevance of annotated corpora in experimental psycholinguistics is discussed more in detail .

  18. Prediction of part shape and associated material properties in hot-press forming using Unite element analysis

    Science.gov (United States)

    Kim, Hwigeon; Ha, Jinjin; Lee, Myoung-Gyu; Barlat, Frederic

    2016-08-01

    The hot-press forming of a U-channel was conducted on a boron-steel blank. The die consisted of two separate parts in order to perform the partial quenching process. The cold die was initially at 25 °C while the heated die was set to five different temperatures, namely, 25, 120, 220, 320 and 400 °C. The cooling temperature history, Vickers hardness and springback of the channel were measured. A thermo-mechanical-metallurgical model, which accounts for the prior austenite deformation effect, was successfully implemented in the LS-DYNA explicit solver to simulate the hot-press forming process under partial quenching conditions. The predicted and experimental results were compared and found in reasonable agreement.

  19. Evaluation of Different Methods for Removing Oral Biofilm in Patients Admitted to the Intensive Care Unit

    Science.gov (United States)

    Oliveira, Maria Sonia; Borges, Alvaro Henrique; Mattos, Fernanda Zanol; Semenoff, Tereza Aparecida Della Vedove; Segundo, Alex Semenoff; Tonetto, Mateus Rodrigues; Bandeca, Matheus Coêlho; Porto, Alessandra Nogueira

    2014-01-01

    Background: The present study aimed to evaluate the different methods for removing oral biofilm in combination with 0.12% chlorhexidine, in patients admitted to the intensive care unit (ICU) of the General University Hospital. Materials and Methods: Initially, the patients were included in the study and underwent periodontal evaluation by means of the visible plaque index (VPI) and gingival bleeding index (GBI). The removal of visible biofilm, by a professional, was carried out using a toothbrush and dental floss, followed by the application of a 0.12% chlorhexidine solution. The patients were included in this randomized and controlled study into four groups (total n = 48), as follows: Chlorhexidine and gauze 12/12 h; chlorhexidine and gauze 24/24 h; chlorhexidine and brushing 12/12 h; chlorhexidine and brushing 24/24 h. The patients underwent the biofilm removal protocol for 7 days and then were subjected to a new clinical evaluation as to VPI and GBI. Data analysis was performed through stratification and arrangement of the records, in order to carry out the associations with health indicators used in the study, and the statistical tests used were Kappa and t-test for independent and paired samples. Results: A decrease in the VPI and GBI values when comparing baseline to the final evaluation for all groups was observed. Conclusion: Based on the methodology, it was possible to concluded that chlorhexidine associated with the mechanical action of the toothbrush or gauze in the times 12 h and 24 h in the ICU environment presented the same results as regards amount of visible biofilm. How to cite the article: Oliveira MS, Borges AH, Mattos FZ, Semenoff TA, Segundo AS, Tonetto MR, Bandeca MC, Porto AN. Evaluation of different methods for removing oral biofilm in patients admitted to the intensive care unit. J Int Oral Health 2014;6(3):61-4. PMID:25083034

  20. Evaluation of Various Methods for Estimating Global Solar Radiation in the Southeastern United States

    Energy Technology Data Exchange (ETDEWEB)

    Woli, Prem; Paz, Joel O.

    2012-05-01

    Global solar radiation Rg is an important input for crop models to simulate crop responses. Because the scarcity of long and continuous records of Rg is a serious limitation in many countries, Rg is estimated using models. For crop-model application, empirical Rg models that use commonly measured meteorological variables, such as temperature and precipitation, are generally preferred. Although a large number of models of this kind exist, few have been evaluated for conditions in the United States. This study evaluated the performances of 16 empirical, temperature- and/or precipitation-based Rg models for the southeastern United States. By taking into account spatial distribution and data availability, 30 locations in the region were selected and their daily weather data spanning eight years obtained. One-half of the data was used for calibrating the models, and the other half was used for evaluation. For each model, location-specific parameter values were estimated through regressions. Models were evaluated for each location using the root-mean-square error and the modeling efficiency as goodness-of-fit measures. Among the models that use temperature or precipitation as the input variable, the Mavromatis model showed the best performance. The piecewise linear regression based Wu et al. model (WP) performed best not only among the models that use both temperature and precipitation but also among the 16 models evaluated, mainly because it has separate relationships for low and high radiation levels. The modeling efficiency of WP was from ~5% to more than 100% greater than those of the other models, depending on models and locations.

  1. GATEWAY Report Brief: Evaluating Tunable LED Lighting in the Swedish Medical Behavioral Health Unit

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-08-23

    Summary of a GATEWAY report evaluation of a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

  2. Social Acceptance of Wind Power in the United States: Evaluating Stakeholder Perspectives (Poster)

    Energy Technology Data Exchange (ETDEWEB)

    Tegen, S.; Lantz, E.

    2009-05-01

    As the wind industry strives to achieve 20% wind energy by 2030, maintaining high levels of social acceptance for wind energy will become increasingly important. Wind Powering America is currently researching stakeholder perspectives in the U.S. market and reviewing findings from wind energy projects around the world to better understand social acceptance barriers. Results from European studies show that acceptance varies widely depending on local community values. A preliminary survey shows similar results in the United States. Further research will be conducted to refine our understanding of key social acceptance barriers and evaluate the best ways to mitigate negative perspectives on wind power.

  3. The death of marriage? The effects of new forms of legal recognition on marriage rates in the United States.

    Science.gov (United States)

    Dillender, Marcus

    2014-04-01

    Some conservative groups argue that allowing same-sex couples to marry reduces the value of marriage to opposite-sex couples. This article examines how changes in U.S. legal recognition laws occurring between 1995 and 2010 designed to include same-sex couples have altered marriage rates in the United States. Using a difference-in-differences strategy that compares how marriage rates change after legal recognition in U.S. states that alter legal recognition versus states that do not, I find no evidence that allowing same-sex couples to marry reduces the opposite-sex marriage rate. Although the opposite-sex marriage rate is unaffected by same-sex couples marrying, it decreases when domestic partnerships are available to opposite-sex couples.

  4. Finite Element Optimization for Nondestructive Evaluation on a Graphics Processing Unit for Ground Vehicle Hull Inspection

    Science.gov (United States)

    2013-08-22

    GPU ,GA, genetic algorithm, FE, optimization, CUDA , Damage, Evaluation 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF... GPU with CUDA architecture [4]). There is however a severe memory limit – 4 GB at present. This would limit large problems as well as optimization...August 2013 UNCLASSIFIED UNCLASSIFIED Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 FE Optimization for NDE on GPUs for Ground

  5. Residual stress evaluation and curvature behavior of aluminum 7050 peen forming processed; Avaliacao da tensao residual em aluminio 7050 conformado pelo processo peen forming

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Rene Ramos de

    2011-07-01

    Shot peening is a superficial cold work process used to increase the fatigue life evaluated by residual stress measurements. The peen forming process is a variant of the shot peening process, where a curvature in the plate is obtained by the compression of the grains near to the surface. In this paper, the influence of the parameters such as: pressure of shot, ball shot size and thickness of aluminum 7050 samples with respect to residual stress profile and resulting arc height was studied. The evaluation of the residual stress profile was obtained by sin{sup 2} {psi} method. The results show that the formation of the curvature arc height is proportional to the shot peening pressure, of spheres size and inversely proportional to the thickness of the sample, and that stress concentration factor is larger for samples shot peened with small balls. On final of this paper presents an additional study on micro strain and average crystallite size, which can evaluate the profile of the samples after blasting. (author)

  6. Multi-compartmental transdermal patch for simultaneous delivery of multiple drugs: formulation and evaluation of newly developed novel dosage form

    Directory of Open Access Journals (Sweden)

    Vijayan Venugopal

    2015-07-01

    Full Text Available Objective: To evaluate the formulation of multi-compartmental transdermal patches for simultaneous delivery of multiple drugs: aceclofenac and serratiopeptidase. Methods: The patch was prepared by simple solvent casting method using hydroxy propyl methyl cellulose K100M as matrix forming agent and dimethyl sulphoxide as permeation enhancer. The prepared transdermal patch was evaluated by physiochemical parameters and in- vitro diffusion studies. Results: The multi-compartmental transdermal patch showed sustained drug release over the period of 12 h. Conclusions: Multicompartmental transdermal patches shows better bioavailability, therapeutic efficacy and very economic as compared with other dosage forms.

  7. Colorado cultural resource survey: cultural resource re-evaluation form [5JA784

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document includes the survey forms necessary to assess cultural resources in Colorado. This document assesses the Allard ranch (5JA784) on Arapaho National...

  8. A study on characterization and evaluation methodologies of radioactive waste forms for safe disposal

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Y. C.; Lee, G. S.; Kim, G. J.; Nam, H.; Seok, J. H. [Yonsei Univ., Seoul (Korea, Republic of)

    2004-02-15

    The contents and scope of the study are summarized as follows : elicitation of significant items for characteristic assessment about stability analysis of radioactive waste forms for safe disposal, compressive strength, free water, leaching rate, and weatherability. Suggestion of assessment methods through the characteristic test of waste forms, comparison of assessment methods and suggestion of suitable testing methods about the above stated 4 items. Assessment modeling development for long-term stability of radioactive waste forms, weatherometric test of waste forms, expectation modeling development through VOM(Valance-Oxygen Model). Suggestion of determination standard together assessment testing methods and description about the standard. Explanation to be suitable guideline and regulation of waste handling and acceptance.

  9. Evaluation of Vitreous and Devitrifying Enamels as Hot Forming Lubricants for Aluminum AA5083 Alloy

    Science.gov (United States)

    Riahi, A. R.; Morales, A. T.; Alpas, A. T.

    2008-06-01

    The adhesion of aluminum to tool surfaces during the hot forming of sheet aluminum alloys presents challenging tribological problems. Graphite and boron nitride are commonly used as aluminum adhesion mitigating solid lubricants for hot forming processes, but lubricant breakdown in high-stress areas, such as corners and bends, remains an issue compromising the quality of the formed parts as well as the tool life. Low-melting temperature enamels may provide an affordable and easy to apply alternative. In this study, vitreous (amorphous glass) and devitrifying (two phase crystalline glass) layers were deposited on the surface of sheet aluminum samples with a sedimentation technique. Enamel lubrication was effective in preventing aluminum transfer to the steel counterface. Hence, the prospect exists for the use of these enamels as aluminum workpiece lubricants in hot forming operations.

  10. Colorado cultural resource survey: cultural resource re-evaluation form [5JA783

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document includes the survey forms necessary to assess cultural resources in Colorado. This document assesses the Case ranch (5JA783) on Arapaho National...

  11. Survey of care and evaluation of East African burn unit feasibility: an academic burn center exchange.

    Science.gov (United States)

    Mitchell, Katrina B; Giiti, Geofrey; Gallagher, James J

    2013-01-01

    Weill Cornell Medical College in New York, partnered with Weill Bugando Medical College and Sekou Toure Regional Referral Hospital, in Mwanza, Tanzania, to consider the development of a burn unit there. This institutional partnership provided a unique opportunity to promote sustainable academic exchange and build burn care capacity in the East African region. A Weill Cornell burn surgeon and burn fellow collaborated with the Sekou Toure department of surgery to assess its current burn care capabilities and potential for burn unit development. All aspects of interdisciplinary burn care were reviewed and institutional infrastructure evaluated. Sekou Toure is a 375-bed regional referral center and teaching hospital of Weill Bugando Medical College. In 2010-2011, it admitted 5244 pediatric patients in total; 100 of these patients were burn-injured children (2% of admissions). There was no specific data kept on percentage of body surface burned, degree of burn, length of stay, or complications. No adult, operative, or outpatient burn data were available. There are two operating theaters. Patient's families perform wound care with nursing supervision. Rehabilitation therapists consult as needed. Meals are provided three times daily by a central kitchen. Public health outreach is possible through village-based communication networks. Infrastructure to support the development of a burn care unit exists at Sekou Toure, but needs increased clinical focus, human resource capacity building, and record-keeping to track accurate patient numbers. A multidisciplinary center could improve record-keeping and outcomes, encourage referrals, and facilitate outreach through villages.

  12. Development of the wireless ultra-miniaturized inertial measurement unit WB-4: preliminary performance evaluation.

    Science.gov (United States)

    Lin, Zhuohua; Zecca, Massimiliano; Sessa, Salvatore; Bartolomeo, Luca; Ishii, Hiroyuki; Takanishi, Atsuo

    2011-01-01

    This paper presents the preliminary performance evaluation of our new wireless ultra-miniaturized inertial measurement unit (IMU) WB-4 by compared with the Vicon motion capture system. The WB-4 IMU primarily contains a mother board for motion sensing, a Bluetooth module for wireless data transmission with PC, and a Li-Polymer battery for power supply. The mother board is provided with a microcontroller and 9-axis inertial sensors (miniaturized MEMS accelerometer, gyroscope and magnetometer) to measure orientation. A quaternion-based extended Kalman filter (EKF) integrated with an R-Adaptive algorithm for automatic estimation of the measurement covariance matrix is implemented for the sensor fusion to retrieve the attitude. The experimental results showed that the wireless ultra-miniaturized WB-4 IMU could provide high accuracy performance at the angles of roll and pitch. The yaw angle which has reasonable performance needs to be further evaluated.

  13. Laboratory evaluation of fan/filter units' aerodynamic and energy performance

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Tengfang; Jeng, Ming-Shan

    2004-07-27

    The paper discusses the benefits of having a consistent testing method to characterize aerodynamic and energy performance of FFUs. It presents evaluation methods of laboratory-measured performance of ten relatively new, 1220 mm x 610 mm (or 4 ft x 2 ft) fan-filter units (FFUs), and includes results of a set of relevant metrics such as energy performance indices (EPI) based upon the sample FFUs tested. This paper concludes that there are variations in FFUs' performance, and that using a consistent testing and evaluation method can generate compatible and comparable FFU performance information. The paper also suggests that benefits and opportunities exist for our method of testing FFU energy performance to be integrated in future recommended practices.

  14. Laboratory evaluation of fan/filter units' aerodynamic and energy performance

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Tengfang; Jeng, Ming-Shan

    2004-07-27

    The paper discusses the benefits of having a consistent testing method to characterize aerodynamic and energy performance of FFUs. It presents evaluation methods of laboratory-measured performance of ten relatively new, 1220 mm x 610 mm (or 4 ft x 2 ft) fan-filter units (FFUs), and includes results of a set of relevant metrics such as energy performance indices (EPI) based upon the sample FFUs tested. This paper concludes that there are variations in FFUs' performance, and that using a consistent testing and evaluation method can generate compatible and comparable FFU performance information. The paper also suggests that benefits and opportunities exist for our method of testing FFU energy performance to be integrated in future recommended practices.

  15. 100-OL-1 Operable Unit Pilot Study: XRF Evaluation of Select Pre-Hanford Orchards

    Energy Technology Data Exchange (ETDEWEB)

    Bunn, Amoret L.; Fritz, Brad G.; Pulsipher, Brent A.; Gorton, Alicia M.; Bisping, Lynn E.; Brandenberger, Jill M.; Pino, Christian; Martinez, Dominique M.; Rana, Komal; Wellman, Dawn M.

    2014-11-20

    Prior to the acquisition of land by the U.S. Department of War in February 1943 and the creation of the Hanford Site, the land along the Columbia River was home to over 1000 people. Farming and orchard operations by both homesteaders and commercial organizations were prevalent. Orchard activities and the associated application of lead arsenate pesticide ceased in 1943, when residents were moved from the Hanford Site at the beginning of the Manhattan Project. Today, the residues from historical application of lead arsenate pesticide persist in some locations on the Hanford Site. In 2012, the U.S. Department of Energy, U.S. Environmental Protection Agency, and Washington State Department of Ecology established the 100-OL-1 Operable Unit (OU) through the Hanford Federal Facility Agreement and Consent Order, known as the Tri-Party Agreement. The pre-Hanford orchard lands identified as the 100-OL-1 OU are located south of the Columbia River and east of the present-day Vernita Bridge, and extend southeast to the former Hanford townsite. The discontinuous orchard lands within 100-OL-1 OU are approximately 20 km2 (5000 ac). A pilot study was conducted to support the approval of the remedial investigation/feasibility study work plan to evaluate the 100-OL-1 OU. This pilot study evaluated the use of a field portable X-ray fluorescence (XRF) analyzer for evaluating lead and arsenic concentrations on the soil surface as an indicator of lead arsenate pesticide residues in the OU. The objectives of the pilot study included evaluating a field portable XRF analyzer as the analytical method for decision making, estimating the nature and extent of lead and arsenic in surface soils in four decision units, evaluating the results for the purpose of optimizing the sampling approach implemented in the remedial investigation, and collecting information to improve the cost estimate and planning the cultural resources review for sampling activities in the remedial investigation. Based on

  16. Experimentally Evaluated Explosion Resistance and Performance of Destruction Unit in Multiple Detonation of Ammunition

    Directory of Open Access Journals (Sweden)

    P. A. Baskakov

    2016-01-01

    Full Text Available The paper presents results of development and experimental investigation of explosion resistance and destruction unit performance in multiple detonation of ammunition with an explosive weight up to 0.7 kg of TNT. A preliminary evaluation of the explosion resistance was carried out using a model of explosion resistance localizer, represented as a thick-walled tube. As a result of explosive tests, the nature and characteristics of tube deformation under repeated explosions have been revealed. The findings allowed us to develop the first embodiment of the destruction unit with a turning non-separable heater and a two-layer localizer, which was heated by the induction field. The explosive life tests have revealed the following drawbacks: low resource localizer, jamming rotating mechanism in contact with the splinters, and impossible replacement of damaged localizer. In the second embodiment of the destruction unit a plate-assembled easychange localizer is mounted on the heater, and it is heated by heat transfer from the core. Tests have shown that, with such a placement, the uniform heating of the localizer is not reached. This leads to incomplete destruction of ammunition. Besides, because of the low strength of the pins connecting the plates, occurrs their rapid destruction. Taking into consideration the shortcomings of the previous two designs, the third option of the destruction unit with a replaceable localizer and induction heating of a localizer has been designed. A localizer material having high mechanical strength at high temperatures and good ferromagnetic properties has been selected. The paper offers an all-metal localizer design with the thickest wall at the bottom that is the most damageable. The paper has experimentally determined a critical deformation of the localizer when destroying the ammunition with varying weight of explosive and defined the heater and bump resource. As a result, the work proposes the destruction unit design

  17. Evaluation of eicosanoid concentrations in stored units of canine packed red blood cells.

    Science.gov (United States)

    Blake, Rachel R; Lee, Jung Hwa; Ross, Matt K; Archer, Todd M; Wills, Robert W; Mackin, Andrew J; Thomason, John M

    2017-01-15

    OBJECTIVE To evaluate eicosanoid concentrations in freshly prepared canine packed RBCs (PRBCs) and to assess changes in eicosanoid concentrations in PRBC units over time during storage and under transfusion conditions. DESIGN Prospective study. SAMPLE 25 plasma samples from 14 healthy Greyhounds. PROCEDURES Plasma samples were obtained during PRBC preparation (donation samples), and the PRBC units were then stored at 4°C until used for transfusion (≤ 21 days later; n = 17) or mock transfusion if expired (22 to 24 days later; 8). Immediately prior to use, 100 mL of saline (0.9% NaCl) solution was added to each unit and a pretransfusion sample was collected. A posttransfusion sample was collected after transfusion or mock transfusion. Concentrations of arachidonic acid, prostaglandin (PG) F2α, PGE2, PGD2, thromboxane B2, 6-keto-PGF1α, and leukotriene B4 were measured by liquid chromatography-mass spectrometry and analyzed statistically. RESULTS Median arachidonic acid concentration was significantly decreased in posttransfusion samples, compared with the concentration in donation samples. Median PGF2α, 6-keto-PGF1α, and leukotriene B4 concentrations were significantly increased in pretransfusion samples, compared with those in donation samples. Median PGF2α, thromboxane B2, and 6-keto-PGF1α concentrations were significantly increased in posttransfusion samples, compared with those in pretransfusion samples. Duration of PRBC storage had significant associations with pretransfusion and posttransfusion arachidonic acid and thromboxane B2 concentrations. CONCLUSIONS AND CLINICAL RELEVANCE Concentrations of several proinflammatory eicosanoids increased in PRBC units during storage, transfusion, or both. Accumulation of these products could potentially contribute to adverse transfusion reactions, and investigation of the potential association between eicosanoid concentrations in PRBCs and the incidence of transfusion reactions in dogs is warranted.

  18. Performance Evaluation of Refrigeration Units in Natural Gas Liquid Extraction Plant

    Directory of Open Access Journals (Sweden)

    Awajiogak Anthony Ujile

    2014-01-01

    Full Text Available This paper has applied thermodynamics principles to evaluate the reliability of 390 m3/hr natural gas processing plant. The thermodynamics equations were utilized in the evaluation, characterization, and numerical simulation of key process parameters in natural gas liquid extraction plant. The results obtained show the comparison of the coefficient of performance, compression ratio, isentropic work, actual work, electrical power requirements, cooling water consumption in intercoolers, compressor power output, compressor capacity, and isentropic, volumetric, and mechanical efficiency of the two-stage refrigeration unit with a flash gas economizer and these were compared with the designed specifications. The second law of thermodynamics was applied in analyzing the refrigeration unit and the result shows that exergetic losses or lost work due to irreversibility falls within operating limit that is less than 1.0%. Similarly, the performance of expansion turbine (expander parameters was monitored and the results indicate a considerable decrease in turbine efficiencies as the inlet gas pressure increases resulting in an increased power output of the turbine leading to a higher liquefaction rate.

  19. Evaluation of EDR-3 vibration, shock, temperature, and humidity recording unit

    Science.gov (United States)

    Rees, Kevin G.; Mondale, C. F.

    1990-07-01

    The purpose of this evaluation was to determine if the self-contained, off-the-shelf, Environmental Data Recorder 3 (EDR-3) could be qualified to monitor shock, vibration, and temperature during rail transportation of space shuttle solid rocket components. The evaluation testing started in November 1989 and continued until June 1990. Two EDR-3 units were used to monitor both on- and off-plant shipments of shuttle components. In addition, extensive testing was performed at Thiokol's Vibration Test facility, T-53. Testing demonstrated that the EDR-3 is capable of successfully monitoring actual shipments of solid rocket hardware. Thiokol metrology has verified the accuracy of temperature monitoring. In addition, calibrated shock/vibration testing demonstrated that the EDR-3 does accurately record acceleration. It is recommended that the vendor modify the EDR-3 data recovery system to allow remote communication via a 30-foot cable. This would permit communication with the unit mounted on a case segment after a rail car cover is installed. The vendor will make this change and produce a new model, designated EDR-3-10. It is further recommended that Thiokol qualify the EDR-3-10 for transportation monitoring of redesigned solid rocket motor (RSRM) components.

  20. Evaluation of Suicide and Intoxication Cases Admitted to our Newly Opened Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Nalan Muhammedoğlu

    2014-09-01

    Full Text Available Aim: The aim of this study was to evaluate the suicide and intoxication cases between April 2011 and April 2013. Methods: We retrospectively analyzed hospital records of patients who were admitted to our intensive care unit due to suicide and intoxication. The age, sex, intoxication causes, laboratory analyses, treatment refusal rates, and the prognosis were evaluated. Results: A total of 308 patients (105 males, 203 females were admitted to the intensive care unit. The mean age of the patients was 27.45±10.26 years (males: 28.70±9.86 years, females: 26.80±10.43 years. There were only 4 patients over 65 years of age. 275 patients had drug intoxication (antidepressant drug, pain killer, antibiotic, etc. and 33 patients had other causes of intoxication. When analyzing the prognosis; a total of 234 patients were discharged after initial treatment and 57 patients were discharged due to treatment refusal. 15 patients were referred for inpatient psychiatric treatment, 1 patient to the Alcohol and Drug Addiction Treatment Center (AMATEM and 1 patient was referred to İstanbul University Medical Faculty due to acute hepatic failure. Conclusion: The patients admitted to our intensive care unit due to suicide and intoxications were mainly females (65.9% and individuals of young age (median age: 27.45 years. Female patients had used antidepressants for suicide attempts and males had used antiflu-acetaminophen combinations. No mortality was observed. (The Me­di­cal Bul­le­tin of Ha­se­ki 2014; 52:153-7

  1. Stochastic Multicriteria Acceptability Analysis for Evaluation of Combined Heat and Power Units

    Directory of Open Access Journals (Sweden)

    Haichao Wang

    2014-12-01

    Full Text Available Combined heat and power (CHP is a promising technology that can contribute to energy efficiency and environmental protection. More CHP-based energy systems are planned for the future. This makes the evaluation and selection of CHP systems very important. In this paper, 16 CHP units representing different technologies are taken into account for multicriteria evaluation with respect to the end users’ requirements. These CHP technologies cover a wide range of power outputs and fuel types. They are evaluated from the energy, economy and environment (3E points of view, specifically including the criteria of efficiency, investment cost, electricity cost, heat cost, CO2 production and footprint. Uncertainties and imprecision are common both in criteria measurements and weights, therefore the stochastic multicriteria acceptability analysis (SMAA model is used in aiding this decision making problem. These uncertainties are treated better using a probability distribution function and Monte Carlo simulation in the model. Moreover, the idea of “feasible weight space (FWS” which represents the union of all preference information from decision makers (DMs is proposed. A complementary judgment matrix (CJM is introduced to determine the FWS. It can be found that the idea of FWS plus CJM is well compatible with SMAA and thus make the evaluation reliable.

  2. Concept and methodology for evaluating core damage frequency considering failure correlation at multi units and sites and its application

    Energy Technology Data Exchange (ETDEWEB)

    Ebisawa, K.; Teragaki, T.; Nomura, S. [Former Incorporated Administrative Agency, Japan Nuclear Safety Organization (Japan); Abe, H., E-mail: Hiroshi_abe@nsr.go.jp [Former Incorporated Administrative Agency, Japan Nuclear Safety Organization (Japan); Shigemori, M.; Shimomoto, M. [Mizuho Information & Research Institute, 2-3, Kanda-Nishikicho, Chiyoda-ku, Tokyo (Japan)

    2015-07-15

    Highlights: • We develop a method to evaluate CDF considering failure correlation at multi units. • We develop a procedure to evaluate correlation coefficient between multi components. • We evaluate CDF at two different BWR units using correlation coefficients. • We confirm the validity of method and correlation coefficient through the evaluation. - Abstract: The Tohoku earthquake (Mw9.0) occurred on March 11, 2011 and caused a large tsunami. The Fukushima Daiichi Nuclear Power Plant with six units were overwhelmed by the tsunami and core damage occurred. Authors proposed the concept and method for evaluating core damage frequency (CDF) considering failure correlation at the multi units and sites. Based on the above method, one of authors developed the procedure for evaluating the failure correlation coefficient and response correlation coefficient between the multi components under the strong seismic motion. These method and failure correlation coefficients were applied to two different BWR units and their CDF was evaluated by seismic probabilistic risk assessment technology. Through this quantitative evaluation, the validity of the method and failure correlation coefficient was confirmed.

  3. What is the use? Application of the short form (SF) questionnaires for the evaluation of treatment effects

    NARCIS (Netherlands)

    Pelle, Aline J.; Kupper, Nina; Mols, Floortje; de Jonge, Peter

    Health status has evolved as a clinical outcome measure that is of great interest in medical care. However, there is still debate about the appropriateness of scoring algorithms for the often used short form questionnaires. Therefore, our aim was to evaluate the consequences of the traditional

  4. The Use of Qualitative Forms of Evaluation for Improving Educational Practice.

    Science.gov (United States)

    Eisner, Elliot W.

    1979-01-01

    Non-quantifiable knowledge, involving sensory information, conceptualization, and imagination, is discussed in relation to educational evalution. Evaluation is discussed in terms of educational connoisseurship, or the art of appreciation; and educational criticism, which informs, interprets, and appraises. (MH)

  5. Evaluation of Nutritional Status in a Teaching Hospital Neonatal Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Mohammadreza Rafati

    2015-02-01

    Full Text Available Background: Extrauterine growth restriction remains a common and serious problem in newborns especially who are small, immature, and critically ill. Very low birth weight infants (VLBW had 97% and 40% growth failure at 36 weeks and 18-22 months post-conceptual age respectively. The postnatal development of premature infants is critically dependent on an adequate nutritional intake that mimics a similar gestational stage. Deficient protein or amino acid administration over an extended period may cause significant growth delay or morbidity in VLBW infants. The purpose of this study was to evaluate current nutritional status in the neonatal intensive care unit in a teaching hospital. Methods: During this prospective observational study, the nutritional status of 100 consecutive critically ill neonates were evaluated by anthropometric and biochemical parameters in a tertiary neonatal intensive care unit. Their demographic characteristics (weight, height and head circumference, energy source (dextrose and lipid and protein were recorded in the first, 5th, 10th, 15th and 20th days of admission and blood samples were obtained to measure serum albumin and prealbumin. The amount of calorie and protein were calculated for all of preterm and term neonates and compared to standard means separately. Results: The calorie and amino acids did not meet in the majority of the preterm and term neonates and mean daily parenteral calorie intake was 30% or lower than daily requirements based on neonates’ weight. Mortality rate was significantly higher in neonates with lower serum albumin and severity of malnutrition but not with serum prealbumin concentration. Conclusion: Infants were studied did not receive their whole of daily calorie and protein requirements and it is recommended early and enough administration of calorie source (dextrose, lipids and amino acids. Prealbumin was a more benefit biochemical parameter than albumin to evaluate short term nutrition

  6. Evaluation of Nutritional Status in a Teaching Hospital Neonatal Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Mohammadreza Rafati

    2015-02-01

    Full Text Available Background:Extrauterine growth restriction remains a common and serious problem in newborns especially who are small, immature, and critically ill. Very low birth weight infants (VLBW had 97% and 40% growth failure at 36 weeks and 18-22 months post-conceptual age respectively. The postnatal development of premature infants is critically dependent on an adequate nutritional intake that mimics a similar gestational stage. Deficient protein or amino acid administration over an extended period may cause significant growth delay or morbidity in VLBW infants. The purpose of this study was to evaluate current nutritional status in the neonatal intensive care unit in a teaching hospital.Methods:During this prospective observational study, the nutritional status of 100 consecutive critically ill neonates were evaluated by anthropometric and biochemical parameters in a tertiary neonatal intensive care unit. Their demographic characteristics (weight, height and head circumference, energy source (dextrose and lipid and protein were recorded in the first, 5th, 10th, 15th and 20th days of admission and blood samples were obtained to measure serum albumin and prealbumin. The amount of calorie and protein were calculated for all of preterm and term neonates and compared to standard means separately. Results: The calorie and amino acids did not meet in the majority of the preterm and term neonates and mean daily parenteral calorie intake was 30% or lower than daily requirements based on neonates’ weight. Mortality rate was significantly higher in neonates with lower serum albumin and severity of malnutrition but not with serum prealbumin concentration. Conclusion: Infants were studied did not receive their whole of daily calorie and protein requirements and it is recommended early and enough administration of calorie source (dextrose, lipids and amino acids. Prealbumin was a more benefit biochemical parameter than albumin to evaluate short term nutrition

  7. Evaluation of incoming calls to intensive care unit for emergency assistance

    Directory of Open Access Journals (Sweden)

    Cevdet Düger

    2013-06-01

    Full Text Available Aim. The aim of this retrospective study was to determine mean admission time after calls, resuscitation success rate, and determine the rate of medical emergency team (MET calls of clinics in hospital by assessing the incoming calls to MET at intensive care unit. Methods. This study was conducted by collecting emergency call forms of 147 patients. The data including age, gender, medical diagnosis, the name of the caller department, cause of call, occurrence time, call time, attending time, medical care termination time and the outcomes were extracted from the forms or patient files. Event declaration time was accepted as minute time difference between occurrence time and call time. Duration of admission was accepted as minute time difference between call times and attending time. Duration of resuscitation was accepted as minute time difference between attending time and medical care termination time. Results. Mean event declaration time was 3.3 ± 3.0 minutes. Mean duration of admission was 3.7 ± 1.6 minutes. Mean duration of resuscitation was 20.5 ± 12.7 minutes. The resuscitation of 84 patients (63.6% was successful while 48 patients (36.4% died at the end of resuscitation. It was found that the patients with a result of successful resuscitation were significantly younger and their duration of resuscitation was significantly shorter. Conclusion. We indicate that MET system is an essential part of in-hospital emergency medical care system. We suggest that a blue code call system should be established by intensive care unit members and announced to all hospital staff.

  8. Student Evaluation of Teaching: A Study Exploring Student Rating Instrument Free-Form Text Comments

    Science.gov (United States)

    Stupans, Ieva; McGuren, Therese; Babey, Anna Marie

    2016-01-01

    Student rating instruments are recognised to be valid indicators of effective instruction, providing a valuable tool to improve teaching. However, free-form text comments obtained from the open-ended question component of such surveys are only infrequently analysed comprehensively. We employed an innovative, systematic approach to the analysis of…

  9. Development of a Rating Form to Evaluate Grant Applications to the Hogg Foundation for Mental Health

    Science.gov (United States)

    Whaley, Arthur L.; Rodriguez, Reymundo; Alexander, Laurel A.

    2006-01-01

    Reliance on subjective grant proposal review methods leads private philanthropies to underfund mental health programs, even when foundations have mental health focuses. This article describes a private mental health foundation's efforts to increase the objectivity of its proposal review process by developing a reliable, valid proposal rating form.…

  10. Test plan for formulation and evaluation of grouted waste forms with shine process wastes

    Energy Technology Data Exchange (ETDEWEB)

    Ebert, W. L. [Argonne National Lab. (ANL), Argonne, IL (United States); Jerden, J. L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-09-01

    The objective of this experimental project is to demonstrate that waste streams generated during the production of Mo99 by the SHINE Medical Technologies (SHINE) process can be immobilized in cement-based grouted waste forms having physical, chemical, and radiological stabilities that meet regulatory requirements for handling, storage, transport, and disposal.

  11. Environmental correlates of cycling: Evaluating urban form and location effects based on Danish micro-data

    DEFF Research Database (Denmark)

    Nielsen, Thomas Alexander Sick; Olafsson, Anton Stahl; Carstensen, Trine Agervig

    2013-01-01

    The paper analyses the environmental correlates of cycling based on Danish transportation and urban form micro-data. The results show that established walkability factors such as density, connectivity and diversity are related to cycling, but access to retail concentrations/centres, public...

  12. Evaluating Access to Eye Care in the Contiguous United States by Calculated Driving Time in the United States Medicare Population.

    Science.gov (United States)

    Lee, Cecilia S; Morris, Aneesha; Van Gelder, Russell N; Lee, Aaron Y

    2016-12-01

    To quantify the proximity to eye care in the contiguous United States by calculating driving routes and driving time using a census-based approach. Cross-sectional study based on United States (US) census data, Medicare payment data, and OpenStreetMap. 2010 US census survey respondents older than 65 years. For each state in the United States, the addresses of all practicing ophthalmologists and optometrists were obtained from the 2012 Medicare Provider Utilization and Payment Data from the Centers for Medicare and Medicaid Services (CMS). The US census data from 2010 then were used to calculate the geolocation of the US population at the block group level and the number of people older than 65 years in each location. Geometries and driving speed limits of every road, street, and highway in the United States from the OpenStreetMap project were used to calculate the exact driving distance and driving time to the nearest eye care provider. Driving time and driving distance to the nearest optometrist and ophthalmologist per state. Driving times for 3.79×10(7) persons were calculated using a total of 3.88×10(7) available roads for the 25 508 optometrists and 17 071 ophthalmologists registered with the CMS. Nationally, the median driving times to the nearest optometrist and ophthalmologist were 2.91 and 4.52 minutes, respectively. Ninety percent of the population lives within a 13.66- and 25.21-minute drive, respectively, to the nearest optometrist and ophthalmologist. While there are regional variations, overall more than 90% of the US Medicare beneficiary population lives within a 30-minute drive of an ophthalmologist and within 15 minutes of an optometrist. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  13. EVALUATION OF ENHANCED VOC REMOVAL WITH SOIL FRACTURING IN THE SRS UPLAND UNIT

    Energy Technology Data Exchange (ETDEWEB)

    Riha, B

    2005-10-31

    The Environmental Restoration Technology Section (ERTS) of the Savannah River National Laboratory (SRNL) conducted pilot scale testing to evaluate the effectiveness of using hydraulic fracturing as a means to improve soil vapor extraction (SVE) system performance. Laboratory and field research has shown that significant amounts of solvents can be entrapped in low permeability zones by capillary forces and removal by SVE can be severely limited due to low flow rates, mass transfer resistance of the hydrophobic compounds by trapped interparticle water, and diffusion resistance. Introducing sand-filled fractures into these tight zones improves the performance of SVE by (1) increasing the overall permeability of the formation and thereby increasing SVE flow rates, (2) shortening diffusion pathways, and (3) increasing air permeability by improving pore water removal. The synergistic effect of the fracture well completion methods, fracture and flow geometry, and pore water removal appears to increase the rate of solvent mass removal over that of increasing flow rate alone. A field test was conducted where a conventional well in the SRS Upland Unit was tested before and after hydraulic fracturing. ERTS teamed with Clemson University through the South Carolina University and Education Foundation (SCUREF) program utilizing their expertise in fracturing and fracture modeling. The goals of the fracturing pilot testing were to evaluate the following: (1) The effect of hydraulic fractures on the performance of a conventional well. This was the most reliable way to remove the effects of spatial variations in permeability and contaminant distribution on relative well performance. It also provided data on the option of improving the performance of existing wells using hydraulic fractures. (2) The relative performance of a conventional SVE well and isolated hydraulic fractures. This was the most reliable indicator of the performance of hydraulic fractures that could be created in a

  14. Evaluation of structural deformations of a mechanical connecting unit oxidizer supplies by thermo-mechanical simulation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang Woo [Dept. of Mechanical Engineering, Institute of Machine Convergence Technology, Hankyong National University, Anseong (Korea, Republic of)

    2016-10-15

    A Mechanical connecting unit (MCU) used in ground facilities for a Liquid propellant rocket (LPR) acts as a bridge between the onboard system and the ground oxidizer filling system. It should be resistant to structural deformations in order to guarantee successful supply of a cryogenic oxidizer and high pressure gases without reduction of sealing capability. The MCU consists of many components and linkages and operates under harsh conditions induced by a cryogenic oxidizer, high pressure gases and other mechanical forces. Thus, the evaluation of structural deformation of the MCU considering complex conditions is expensive and time consuming. The present study efficiently evaluates the structural deformations of the key components of the MCU by Thermo-mechanical simulation (TMS) based on the superposition principle. Deformations due to the mechanical loadings including weights, pressures, and spring forces are firstly evaluated by using a non-linear flexible body simulation module (FFlex) of Multi-body dynamics (MBD) software, RecurDyn. Then, thermal deformations for the deformed geometries obtained by RecurDyn were subsequently calculated. It was conducted by using a Finite element (FE) analysis software, ANSYS. The total deformations for the onboard plate and multi-channel plate in the connecting section due to the mechanical and thermal loadings were successfully evaluated. Moreover, the outer gaps at six points between two plates were calculated and verified by comparison to the measured data. Their values and tendencies showed a good agreement. The author concluded that the TMS using MBD software considering flexible bodies and an FE simulator can efficiently evaluate structural deformations of the MCU operating under the complex load and boundary conditions.

  15. Initial evaluation of children admitted on the Paediatric Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Esperanza Arce Delgado

    2007-09-01

    Full Text Available The initial evaluation of the child, when admitted on the Paediatric Intensive Unit, is a essential tool and key piece as a starting point on the development of a specific Care Plan for each child. Therefore, it is necessary the existence of a protocol, according to a rigorous methodology, so that cares will have quality and thus, it will be avoided that each nursing professional will act in a different way, according to his intuition, beliefs or improvisation capacity.The initial evaluation of the child will allow us not only to coordinate the interventions, but also to give continuity to the cares.The initial evaluation of the child document is a nursing register that is part of the clinical register of the paediatric patient. Nursing registers turn to be the best approximation of what nowadays is our job’s practice, and they are, therefore, necessary for us to be judged by a professional perspective and to make it possible to classify the services we carry out to the society.

  16. Evaluation of nosocomial infection risk using APACHE II scores in the neurological intensive care unit.

    Science.gov (United States)

    Li, Hai-Ying; Li, Shu-Juan; Yang, Nan; Hu, Wen-Li

    2014-08-01

    To evaluate the feasibility and accuracy of using the Acute Physiology, Age and Chronic Health Evaluation II (APACHE II) scoring system for predicting the risk of nosocomial infection in the neurological intensive care unit (NICU), 216 patients transferred to NICU within 24hours of admission were retrospectively evaluated. Based on admission APACHE II scores, they were classified into three groups, with higher APACHE II scores representing higher infectious risk. The device utilization ratios and device-associated infection ratios of NICU patients were analyzed and compared with published reports on patient outcome. Statistical analysis of nosocomial infection ratios showed obvious differences between the high-risk, middle-risk and low-risk groups (pAPACHE II model in predicting the risk of nosocomial infection was 0.81, which proved to be reliable and consistent with the expectation. In addition, we found statistical differences in the duration of hospital stay (patient-days) and device utilization (device-days) between different risk groups (pAPACHE II scoring system was validated in predicting the risk of nosocomial infection, duration of patient-days and device-days, and providing accurate assessment of patients' condition, so that appropriate prevention strategies can be implemented based on admission APACHE II scores.

  17. New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.

    Science.gov (United States)

    Carneiro, Paula F; do Nascimento, Samara B; Pinto, Antonio V; Pinto, Maria do Carmo F R; Lechuga, Guilherme C; Santos, Dilvani O; dos Santos Júnior, Helvécio M; Resende, Jackson A L C; Bourguignon, Saulo C; Ferreira, Vitor F

    2012-08-15

    New oxirane derivatives were synthesized using six naphthoquinones as the starting materials. Our biological results showed that these oxiranes acted as trypanocidal agents against Trypanosoma cruzi with minimal cytotoxicity in the VERO cell line compared to naphthoquinones. In particular, oxirane derivative 14 showed low cytotoxicity in a mammalian cell line and exhibited better activity against epimastigote forms of T.cruzi than the current drug used to treat Chagas disease, benznidazole.

  18. Long-term evaluation of the degradation behavior of three apatite-forming calcium phosphate cements.

    Science.gov (United States)

    An, Jie; Liao, Hongbing; Kucko, Nathan W; Herber, Ralf-Peter; Wolke, Joop G C; van den Beucken, Jeroen J J P; Jansen, John A; Leeuwenburgh, Sander C G

    2016-05-01

    Calcium phosphate cements (CPCs) are injectable bone substitutes with a long clinical history because of their biocompatibility and osteoconductivity. Nevertheless, their cohesion upon injection into perfused bone defects as well as their long-term degradation behavior remain major clinical challenges. Therefore, the long-term degradation behavior of two types of α-tricalcium phosphate-based, apatite-forming CPCs was compared to a commercially available apatite-forming cement, that is HydroSet™ . Carboxyl methylcellulose (CMC) was used as cohesion promotor to improve handling properties of the two experimental cements, whereas poly (d, l-lactic-co-glycolic) acid (PLGA) microparticles were added to introduce macroporosity and stimulate CPC degradation. All three CPCs were injected into defects drilled into rabbit femoral condyles and explanted after 4, 12, or 26 weeks, after which the bone response was assessed both qualitatively and quantitatively. CPCs without PLGA microparticles degraded only at the periphery of the implants, while the residual CPC volume was close to 90%. On the contrary, bone ingrowth was observed not only at the periphery of the CPC, but also throughout the center of the implants after 26 weeks of implantation for the PLGA-containing CPCs with a residual CPC volume of approximately 55%. In conclusion, it was shown that CPC containing CMC and PLGA was able to induce partial degradation of apatite-forming CPCs and concomitant replacement by bone tissue.

  19. Evaluation of temperature rise with different curing methods and units in two composite resins

    Directory of Open Access Journals (Sweden)

    Tabatabaei M

    2006-01-01

    Full Text Available Background and Aim: The majority of commercial curing units in dentistry are of halogen lamp type. The new polymerizing units such as blue LED are introduced in recent years. One of the important side effects of light curing is the temperature rise in composite resin polymerization which can affect the vitality of tooth pulp. The purpose of this study was to evaluate the temperature rise in two different composite resins during polymerization with halogen lamps and blue LED. Materials and Methods: This experimental study investigated the temperature rise in two different composites (Hybrid, Tetric Ceram/Nanofilled, Filteke Supreme of A2 shade polymerized with two halogen lamps (Coltolux 50, 350 mW/cm2 and Optilux 501 in standard, 820 mW/cm2 and Ramp, 100-1030 mW/cm2 operating modes and one blue LED with the intensity of 620 mW/cm2. Five samples for each group were prepared and temperature rise was monitored using a k-type thermocouple. Data were analyzed by one-way ANOVA, two-way ANOVA and Tukey HSD tests with P<0.05 as the limit of significance. Results: Light curing units and composite resins had statistically significant influence on the temperature rise (p<0.05. Significantly, lower temperature rise occurred in case of illumination with Coltolux 50.There was no significant difference between Optilux 501 in standard curing mode and LED. Tetric Ceram showed higher temperature rise. Conclusion: According to the results of this study the high power halogen lamp and LED could produce significant heat which may be harmful to the dental pulp.

  20. [Evaluation of outpatient treatment units according to the Crime Victims' Regulation Act].

    Science.gov (United States)

    Bollmann, Kirsten; Schürmann, Ivonne; Nolting, Björn; Dieffenbach, Ina; Fischer, Gottfried; Zurek, Gisela; Bering, Robert; Heuft, Gereon

    2012-01-01

    Over the past years, 35 trauma outpatient units have been established in accordance with the Crime Victims' Compensation Act in the federal state of North Rhine-Westphalia (Germany) for both children and adolescents as well as for adults. They are operated by the social welfare authorities and, since 2008, by the regional authorities of Westphalia-Lippe and Rhineland. They enable victims to receive qualified psychotraumatological help within the first few days after suffering violence. Since trauma units have now been set up across most parts of this federal state, the time has come to assess the effectiveness of their acute care provision to victims of violence. In 2007, on the order of the Ministry of Labour, Health and Social Affairs of the federal state of North Rhine-Westphalia, trauma outpatient units were subjected to scientific evaluation. In 17 trauma outpatient units, a data assessment protocol was officially implemented that included repeat measurements (immediately before the initial contact, after completion of intervention, at follow-up six months after intervention) of traumatized subjects aged 14 and older. Socio-demographic data were gathered, and the scores of the Impact of Event Scale - Revised (IES-R), the Symptom Checkliste-27 (SCL-27), the simplified Beck Depressions Inventory (BDI-V), the Global Assessment of Functioning Scale (GAF) as well as the Cologne Risk Index (CRI) (expert rating) were collected. Nearly three-fourths (65.9 %) of the traumatic experiences of the 211 patients investigated can be characterized as type-1 traumatisation. 31.8 % of patients were victims of crimes involving violations of the right to sexual self-determination (94.0 % of sexual offences being committed against girls and women). Crimes against physical integrity, which according to crime statistics are the most frequent of crimes against individuals (88.8 %, 34.8 % females), were suffered by 36.0 % of all patients of the trauma outpatient units (63.2 % being

  1. Evaluation of wear rate of dental composites polymerized by halogen or LED light curing units

    Directory of Open Access Journals (Sweden)

    Alaghehmand H.

    2006-08-01

    Full Text Available Background and Aim: Sufficient polymerization is a critical factor to obtain optimum physical properties and clinical efficacy of resin restorations. The aim of this study was to evaluate wear rates of composite resins polymerized by two different systems Light Emitting Diodes (LED to and Halogen lamps. Materials and Methods: In this laboratory study, 20 specimens of A3 Tetric Ceram composite were placed in brass molds of 2*10*10 mm dimensions and cured for 40 seconds with 1 mm distance from surface. 10 specimens were cured with LED and the other 10 were cured with Halogen unit. A device with the ability to apply force was developed in order to test the wear of composites. After storage in distilled water for 10 days, the specimens were placed in the wear testing machine. A chrome cobalt stylus with 1.12 mm diameter was applied against the specimens surfaces with a load of 2 kg. The weight of each samples before and after 5000, 10000, 20000, 40000, 80000 and 120000 cycles was measured using an electronic balance with precision of 10-4 grams. Data were analyzed using t test and paired t test. P0.05. Conclusion: Based on the results of this study, LED and halogen light curing units resulted in a similar wear rate in composite resin restorations.

  2. Evaluation of obstetric admissions to intensive care unit of a tertiary referral center in coastal India

    Directory of Open Access Journals (Sweden)

    Poornima B Ramachandra Bhat

    2013-01-01

    Full Text Available Background and Aim: To evaluate the occurrence, indications, course, interventions, and outcome of obstetric patients admitted to the intensive care unit (ICU. Design: Retrospective study. Setting: ICU of a Medical College Hospital. Materials and Methods: The data collected were age, parity, obstetric status, primary diagnosis, interventions, and outcome of obstetric patients admitted to the ICU from Jan 2005 to June 2011. Results: Total deliveries were 16,804 in 6.5 years. Obstetric admissions to the ICU were (n = 65 which constitutes 0.39% of deliveries. Majority of the admissions were in the postpartum period (n = 46, 70.8%. The two common indications for admission were obstetric hemorrhage (n = 18, 27.7% and pregnancy related hypertension with its complications (n = 17, 26.2%. The most common intervention was artificial ventilation (n = 41, 63%. The mortality among obstetric admissions in the ICU was (33.8% (22/65. The patients appropriate for High Dependency Unit (HDU care was (32.3% (21/65. The statistical analysis was done by fractional percentage and Chi-square test. Conclusions: Hemorrhage and pregnancy-related hypertension with its complications are the two common indications for ICU admissions. The need for a HDU should be considered.

  3. Full-scale performance testing and evaluation of unitized curtain walls

    Directory of Open Access Journals (Sweden)

    E. Ilter

    2015-06-01

    Full Text Available Unitized curtain wall systems have been widely seen on high-rise buildings’ facades by bringing benefits with regard to ease of construction, lightness, etc. However, some design and application problems related to structural and infiltration performance of a facade system might arise during its life cycle, which is difficult for the building to compensate. This paper presents a comparative analysis of the structural and infiltration performance of the two identically detailed and produced unitized curtain wall system mock-ups. In order to understand long-term environmental effects on the curtain wall system, a fatigue process was applied on one system in addition to the standard test procedures, while the standard test procedure was applied on the other reference specimen. The tests on the two identical specimens were conducted in accordance with TS EN 13830 and AAMA 501.4 Standards. As a result of air infiltration and wind load resistance tests, air infiltration and frontal deflection values on the facade surface were obtained. Hence, experimental performance of the systems was compared and the effect of the fatigue procedure on the facade performance was evaluated.  

  4. Evaluation and art therapy treatment of the burnout syndrome in oncology units.

    Science.gov (United States)

    Italia, Simona; Favara-Scacco, Cinzia; Di Cataldo, Andrea; Russo, Giovanna

    2008-07-01

    We undertook a pilot study to evaluate and potentially reduce the level of burnout in the operators of two oncology centers. The study included 65 doctors and nurses of an adult (Group A) and a pediatric oncology unit (Group B). We used the Maslach Burnout Inventory to estimate the level of burnout obtained in three dimensions: emotional exhaustion, distancing (cognitive and emotional) and reduced personal achievement. Data showed a medium-high level of burnout in Group A and a medium-low level in Group B. In the second part of the study, Group B underwent a program of art therapy interventions with the aim of reducing the level of burnout. Comparing the responses from Group B participants before and after the intervention indicated a statistically significant decreased level of burnout. In conclusion, burnout syndrome exists among oncology unit personnel and can be effectively treated with art therapies. Attention devoted to this aspect is required in order to improve the workers' well-being, thus enhancing attention and dedication to patients.

  5. Emergy Evaluation of Dwelling Operation in Five Housing Units of Montreal Island, Canada

    Directory of Open Access Journals (Sweden)

    Ricardo Enrique Vega-Azamar

    2017-04-01

    Full Text Available Sustainability of cities and the environmental implications of high resource utilization by the domestic sector are growing concerns related to urban regions. Well-informed urban planning decision-making is an essential tool to help in the task and, for that, an important point to consider is the influence of parameters like residential density and housing typology on the intensity of resource utilization. Emergy synthesis, a life-cycle energy analysis methodological approach that considers the interaction of natural and human-made flows, was used to evaluate the environmental support for dwelling operational stage in five typical present-day housing units on the island of Montreal. As expected, resource utilization, measured as total emergy used, was positively correlated to housing unit size both with respect to number of occupants and dwelling size. Results suggest that variables affecting notably the intensity of resource utilization are per household income and per dweller habitable space and, while a higher income increased per capita emergy in all cases, increasing space availability per resident did not result in a decrease of empower density after 50 m2/person. Future work should consider lower and higher densities and analyses at the scale of blocks, neighborhoods and urban planning zones.

  6. Forming a Belief: The Contribution of Comprehension to the Evaluation and Persuasive Impact of Argumentative Text

    Science.gov (United States)

    Diakidoy, Irene-Anna N.; Christodoulou, Stelios A.; Floros, Georgios; Iordanou, Kalypso; Kargopoulos, Philip V.

    2015-01-01

    Background: Research has shown substantial belief change as a result of reading text and the pervasive influence of prior belief in the evaluation of short arguments. Both outcomes have been attributed to the depth to which the text or the argument has been processed. This study brings together critical thinking and text comprehension research by…

  7. Rheology as a tool for evaluation of melt processability of innovative dosage forms

    DEFF Research Database (Denmark)

    Aho, Johanna Maaria; Boetker, Johan P; Baldursdottir, Stefania

    2015-01-01

    for the process simulations which are also becoming increasingly important. The authors aim to give an overview to the basics of rheology and summarize examples of the studies where rheology has been utilized in setting up or evaluating extrusion processes. Furthermore, examples of different experimental set...

  8. Qualitative evaluation of a form for standardized information exchange between orthopedic surgeons and occupational physicians

    NARCIS (Netherlands)

    E. Faber (Elske); A. Burdorf (Alex); A.L. van Staa (AnneLoes); H.S. Miedema (Harald); J.A.N. Verhaar (Jan)

    2006-01-01

    textabstractBACKGROUND: Both occupational physicians and orthopedic surgeons can be involved in the management of work relevant musculoskeletal disorders. These physicians hardly communicate with each other and this might lead to different advice to the patient. Therefore, we evaluated a standardize

  9. Theoretical evaluation of the efficiency of gas single-stage reciprocating compressor medium pressure units

    Science.gov (United States)

    Busarov, S. S.; Vasil'ev, V. K.; Busarov, I. S.; Titov, D. S.; Panin, Ju. N.

    2017-08-01

    Developed earlier and tested in such working fluid as air, the technology of calculating the operating processes of slow-speed long-stroke reciprocating stages let the authors to obtain successful results concerning compression of gases to medium pressures in one stage. In this connection, the question of the efficiency of the application of slow-speed long-stroke stages in various fields of technology and the national economy, where the working fluid is other gas or gas mixture, is topical. The article presents the results of the efficiency evaluation of single-stage compressor units on the basis of such stages for cases when ammonia, hydrogen, helium or propane-butane mixture is used as the working fluid.

  10. Fitness for service evaluation of a horizontal gas separator in a compressing unit

    Energy Technology Data Exchange (ETDEWEB)

    Seijas, A.; Ledezma, M. [INTEVEP S.A., Los Teques (Venezuela)

    1996-12-01

    An automatic ultrasonic inspection of a horizontal separator revealed cracking in various structural welds of the shell wall. The pressure vessel has been working in a gas compressing unit for several years. A review of the operation history (including fluids, pressure and temperature) indicated the cracking was probably associated with hydrogen induced cracking (HIC). To assure mechanical integrity a Fitness for Service Assessment was conducted based on fracture mechanics procedures. Using the fitness-for-service document and the computer software of the Materials Properties Council (MPC), limiting flaw size curves were obtained. The cracks were evaluated to determine their effect in the structural integrity of the pressure vessel, and to define the inspection program for the future.

  11. Closed-form evaluation of two-dimensional static lattice sums

    Science.gov (United States)

    Yakubovich, S.; Drygas, P.; Mityushev, V.

    2016-11-01

    Closed-form formulae for the conditionally convergent two-dimensional (2D) static lattice sums S2 (for conductivity) and T2 (for elasticity) are deduced in terms of the complete elliptic integrals of the first and second kind. The obtained formulae yield asymptotic analytical formulae for the effective tensors of 2D composites with circular inclusions up to the third order in concentration. Exact relations between S2 and T2 for different lattices are established. In particular, the value S2=π for the square and hexagonal arrays is discussed and T2=π/2 for the hexagonal is deduced.

  12. Evaluation of a short-form of the Berg Card Sorting Test.

    Science.gov (United States)

    Fox, Christopher J; Mueller, Shane T; Gray, Hilary M; Raber, Jacob; Piper, Brian J

    2013-01-01

    The Psychology Experimental Building Language http://pebl.sourceforge.net/ Berg Card Sorting Test is an open-source neurobehavioral test. Participants (N = 207, ages 6 to 74) completed the Berg Card Sorting Test. Performance on the first 64 trials were isolated and compared to that on the full-length (128 trials) test. Strong correlations between the short and long forms (total errors: r = .87, perseverative response: r = .83, perseverative errors r = .77, categories completed r = .86) support the Berg Card Sorting Test-64 as an abbreviated alternative for the full-length executive function test.

  13. Evaluation of a Short-Form of the Berg Card Sorting Test

    OpenAIRE

    Fox, Christopher J.; Mueller, Shane T.; Hilary M Gray; Jacob Raber; Piper, Brian J.

    2013-01-01

    The Psychology Experimental Building Language http://pebl.sourceforge.net/ Berg Card Sorting Test is an open-source neurobehavioral test. Participants (N = 207, ages 6 to 74) completed the Berg Card Sorting Test. Performance on the first 64 trials were isolated and compared to that on the full-length (128 trials) test. Strong correlations between the short and long forms (total errors: r = .87, perseverative response: r = .83, perseverative errors r = .77, categories completed r = .86) suppor...

  14. THE INTERNET AS INFORMATIONAL SOURCE FOR MIS: THE PROCESSES OF CAPTATION AND THE FORMS OF EVALUATION

    Directory of Open Access Journals (Sweden)

    Edson Crescitelli

    2007-01-01

    Full Text Available This article discusses the use and the ways of assessment of the internet as a source of information due to the agility that this way has been providing to the Marketing Information System, which also shows to be fragile in terms of reliability of the available information The study consists of an exploratory research, which includes literature review and multiple case studies, and presents as its objective the understanding of how the internet is used in the processes of data source definition and evaluation in a company, from the user’s point of view. The results indicate that the internet is an important source of information, but there is little systematization in the information collection and the sources evaluation is based only on the users’ individual and practical knowledge

  15. Forms and Levels of Integration: Evaluation of an Interdisciplinary Team-Building Project

    Directory of Open Access Journals (Sweden)

    Andrea Armstrong

    2013-01-01

    Full Text Available Team science models are frequently promoted as the best way to study complex societal and environmental problems. Despite increasing popularity, there is relatively little research on the processes and mechanisms that facilitate the emergence of integration of interdisciplinary teams. This article evaluates a suite of recent team-building and grant-writing activities designed to address water management in the Western U.S. We use qualitative methods to document the emergence of integrative capacity at the individual, group, and institutional levels, with particular attention to the role of graduate students and non-academic practitioners in a team science planning project. Our findings highlight the importance of social integration as a basis for conceptual integration and an ability to relate these concepts to real-world problems. The findings also demonstrate the value of qualitative evaluation measures of team readiness, capacity, and intellectual outputs to complement conventional evaluation indicators that rely on quantitative scientific outputs, particularly for team science projects still in the planning stages.

  16. Development and evaluation of modified release wax matrix tablet dosage form for tramadol hydrochloride

    Directory of Open Access Journals (Sweden)

    Paresh Ramesh Mahaparale

    2015-01-01

    Full Text Available The objective of this study was to develop modified release dosage forms of tramadol hydrochloride using wax matrix system by melt granulation method. The effect of various waxes, concentration of waxes, effect of excipients on the release profile of drug from wax matrix system was studied. Release retardant effect was observed in the order of hydrogenated vegetable oil (HVO > compritol >precirol. This may be due to more lipophilicity imparted by HVO than any other waxy substances. It was also observed that as ratio of drug: Wax was increased, it sustained release of drug for more time. This may be due to proper embedment/entrapment of drug in sufficient wax matrix system. In case of excipients, release retardant effect was found in order of dicalcium phosphate (DCP > microcrystalline cellulose (MCC > lactose. DCP is insoluble which helps in release retardation of drug. MCC is hydrophilic swellable polymer which showed release of drug by swelling. Lactose is soluble excipient which get dissolved and formed channels for entry of dissolution medium and release of drug occurred by erosion mechanism. Wax matrix tablets were found to be stable.

  17. Nasal administration of metoclopramide from different dosage forms: in vitro, ex vivo, and in vivo evaluation.

    Science.gov (United States)

    Tas, Cetin; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Tasdemir, Umut; Altunay, Hikmet

    2009-04-01

    Nasal drug delivery is an interesting route of administration for metoclopramide hydrochloride (MTC) in preventing different kind of emesis. Currently, the routes of administration of antiemetics are oral or intravenous, although patient compliance is often impaired by the difficulties associated with acute emesis or invasiveness of parenteral administration. In this perspective, nasal dosage forms (solution, gel, and lyophilized powder) of MTC were prepared by using a mucoadhesive polymer sodium carboxymethylcellulose (NaCMC). In vitro and ex vivo drug release studies were performed in a modified horizontal diffusion chamber with cellulose membrane and excised cattle nasal mucosa as diffusion barriers. The tolerance of nasal mucosa to the formulation and its components were investigated using light microscopy. In vivo studies were carried out for the optimized formulations in sheep and the pharmacokinetics parameters were compared with oral solution and IV dosage form. The release of MTC from solution and powder formulations was found to be higher than gel formulation (p nasal bioavailability of gel is higher than those of solution and powder (p nasal residence time and thereby nasal absorption.

  18. A theoretical approach to evaluate the release rate of acetaminophen from erosive wax matrix dosage forms.

    Science.gov (United States)

    Agata, Yasuyoshi; Iwao, Yasunori; Shiino, Kai; Miyagishima, Atsuo; Itai, Shigeru

    2011-07-29

    To predict drug dissolution and understand the mechanisms of drug release from wax matrix dosage forms containing glyceryl monostearate (GM; a wax base), aminoalkyl methacrylate copolymer E (AMCE; a pH-dependent functional polymer), and acetaminophen (APAP; a model drug), we tried to derive a novel mathematical model with respect to erosion and diffusion theory. Our model exhibited good agreement with the whole set of experimentally obtained values pertaining to APAP release at pH 4.0 and pH 6.5. In addition, this model revealed that the eroding speed of wax matrices was strongly influenced by the loading content of AMCE, but not that of APAP, and that the diffusion coefficient increased as APAP loading decreased and AMCE loading increased, thus directly defining the physicochemical properties of erosion and diffusion. Therefore, this model might prove a useful equation for the precise prediction of dissolution and for understanding the mechanisms of drug release from wax matrix dosage forms. Copyright © 2011 Elsevier B.V. All rights reserved.

  19. Development and evaluation of fast forming nano-composite hydrogel for ocular delivery of diclofenac.

    Science.gov (United States)

    Li, Xingyi; Zhang, Zhaoliang; Chen, Hao

    2013-05-01

    In this paper, a fast forming nano-composite hydrogel was developed for potential application in ocular drug delivery. The optical transmission (OT) as well as rheological properties of nano-composite hydrogel was characterized. The developed nano-composite hydrogel given a high diclofenac micelles loading and provided a sustained release manner of diclofenac within 6h. The developed nano-composite hydrogel formulation was administrated into the eye as flowable solution, quickly forming a hydrogel that is able to resist of the blinking and flushing of tear, yet resulting in the prolonged residence time of pre-corneal. In vivo eye irritation test suggested that the developed nano-composite hydrogel was none-eye irritation might be suitable for various ocular applications. In vivo pharmacokinetic study indicated that the developed nano-composite hydrogel could significantly increase the bioavailability of diclofenac and maintain the concentration of diclofenac in aqueous humor above MEC at least 24h after administration as compared with that of the commercial diclofenac sodium eye drops, which might be able to reduce the frequency of administration for patients.

  20. Characterization and evaluation of novel film forming polymer for drug delivery.

    Science.gov (United States)

    Mundada, Artish; Satturwar, Prashant; Fulzele, Suniket; Joshi, Sudhir; Dorle, Avinash

    2011-01-01

    DB is a whitish to yellowish resin, characterized initially in terms of solubility, acid value, molecular weight (Mw), polydispersity index (Mw/Mn) and glass transition temperature (Tg). Neat plasticized films of DB (Damar Batu) are investigated for mechanical, water vapor transmission and moisture absorption properties. To improve the mechanical properties of the free films dibutyl sebacate, a hydrophobic plasticizer was added to film composition. The biomaterial was further investigated for sustaining the drug release from spherical units (multiparticulates). The core of pellet was prepared using Diclofenac sodium (10% w/w) as a model drug by extrusion and speronization. The drug containing pellets were coated using DB plasticized film-coating solutions. With 2% coat build-up, sustained drug release up to 10 h was achieved with coating solution containing 20% and 30% w/w (based on DB weight) plasticizers. Less than 3% drug was released in the first 2 h which may be explained in terms of the insolubility of DB and the drug in acidic milieu. The release from pellets coated using DB film coating solution containing 20% and 30% plasticizers followed first order release pattern. DB seems to be a promising film former for pharmaceutical coating due to its reasonably good mechanical properties, low water vapor transmission and sustained release capability.

  1. Corrosion evaluation of zirconium doped oxide coatings on aluminum formed by plasma electrolytic oxidation.

    Science.gov (United States)

    Bajat, Jelena; Mišković-Stanković, Vesna; Vasilić, Rastko; Stojadinović, Stevan

    2014-01-01

    The plasma electrolytic oxidation (PEO) of aluminum in sodium tungstate (Na(2)WO(4) · (2)H(2)O) and Na(2)WO(4) · (2)H(2)O doped with Zr was analyzed in order to obtain oxide coatings with improved corrosion resistance. The influence of current density in PEO process and anodization time was investigated, as well as the influence of Zr, with the aim to find out how they affect the chemical content, morphology, surface roughness, and corrosion stability of oxide coatings. It was shown that the presence of Zr increases the corrosion stability of oxide coatings for all investigated PEO times. Evolution of EIS spectra during the exposure to 3% NaCl, as a strong corrosive agent, indicated the highest corrosion stability for PEO coating formed on aluminum at 70 mA/cm(2) for 2 min in a zirconium containing electrolyte.

  2. SEM evaluation of resin-carious dentin interfaces formed by two dentin adhesive systems

    Science.gov (United States)

    Hsu, Kuang-Wei; Marshall, Sally J.; Pinzon, Lilliam M.; Watanabe, Larry; Saiz, Eduardo; Marshall, Grayson W.

    2008-01-01

    Objectives We investigated the influence of dentin tubule direction and identifiable zone of carious dentin on the microstructure and the thickness of the hybrid-like layer (HL) formed by self-etch and etch-rinse adhesive systems. Methods An etch-rinse and a self-etching adhesive were bonded to dentin carious zones divided into groups with parallel or perpendicular orientation relative to the dentin tubules at the resin-carious dentin interface (N = 5/variable). Bonds were prepared to each of the four zones of carious dentin apparent after staining with Caries Detector: pink, light pink, transparent and apparently normal Six non-carious third molars were controls. The microstructure and thickness of the HL were determined by SEM.and compared using three-way ANOVA and Tukey's multiple comparisons (pcarious zone. PMID:18155289

  3. Preliminary evaluation of alternative waste form solidification processes. Volume I. Identification of the processes.

    Energy Technology Data Exchange (ETDEWEB)

    Treat, R.L.; Nesbitt, J.F.; Blair, H.T.; Carter, J.G.; Gorton, P.S.; Partain, W.L.; Timmerman, C.L.

    1980-04-01

    This document contains preconceptual design data on 11 processes for the solidification and isolation of nuclear high-level liquid wastes (HLLW). The processes are: in-can glass melting (ICGM) process, joule-heated glass melting (JHGM) process, glass-ceramic (GC) process, marbles-in-lead (MIL) matrix process, supercalcine pellets-in-metal (SCPIM) matrix process, pyrolytic-carbon coated pellets-in-metal (PCCPIM) matrix process, supercalcine hot-isostatic-pressing (SCHIP) process, SYNROC hot-isostatic-pressing (SYNROC HIP) process, titanate process, concrete process, and cermet process. For the purposes of this study, it was assumed that each of the solidification processes is capable of handling similar amounts of HLLW generated in a production-sized fuel reprocessing plant. It was also assumed that each of the processes would be enclosed in a shielded canyon or cells within a waste facility located at the fuel reprocessing plant. Finally, it was assumed that all of the processes would be subject to the same set of regulations, codes and standards. Each of the solidification processes converts waste into forms that may be acceptable for geological disposal. Each process begins with the receipt of HLLW from the fuel reprocessing plant. In this study, it was assumed that the original composition of the HLLW would be the same for each process. The process ends when the different waste forms are enclosed in canisters or containers that are acceptable for interim storage. Overviews of each of the 11 processes and the bases used for their identification are presented in the first part of this report. Each process, including its equipment and its requirements, is covered in more detail in Appendices A through K. Pertinent information on the current state of the art and the research and development required for the implementation of each process are also noted in the appendices.

  4. Publishing Time-Frame Evaluation for Doctoral Students in United Kingdom

    Directory of Open Access Journals (Sweden)

    Andrada Elena URDA-CÎMPEAN

    2014-09-01

    Full Text Available The first objective of the study was to compute the time to completion and publication of original scientific publications for medical doctoral students in the UK. A second objective was to evaluate if PhD theses format (monograph or publication-based can influence the time to completion and publication of original scientific publications. We assessed a small sample of free full text medical doctoral theses from universities in the United Kingdom (mostly from the University of Manchester, which have produced at least 2 original scientific publications by the end of the doctoral studies. The time elapsed between 2 consecutive publications from the same thesis was considered an approximation of the time to completion and publication of the second publication. In the case of prospective theses, the median time to completion and publication of original scientific publications from medical doctoral theses was 10.17 months. We found that there was a statistically significant difference between the time (to completion and publication medians of the publications from traditional theses format and of the publications from publication-based theses format. Time to completion and publication of original scientific publications for medical doctoral students needs to be further evaluated on a larger scale, based on more theses from several medical faculties in the UK.

  5. Evaluation of antibiotic prescriptions for urinary tract infections in a geriatric rehabilitation unit.

    Science.gov (United States)

    Afekouh, Hind; Baune, Patricia; De Falvelly, Diane; Guermah, Fatima; Ghitri, Saïda; Haber, Nicole

    2017-03-01

    Prescription of antibiotic in elderly patients must follow guidelines. to study the quality of antibiotic prescriptions for urinary tract infections (UTI) in the geriatric rehabilitation unit. Over a four-month period, all the antibiotics treatments prescribed for UTI in the rehabilitation ward were analyzed prospectively by medical experts and confronted with the recommendations of the local antibiotic guidelines. The methodology was based on Gyssens' algorithm. Treatments were considered appropriate if indication, choice of the molecule, duration and dose were approved by the experts, unnecessary if the indication was incorrect, and inappropriate in all other cases. The re-assessment of the prescription between 48 and 72 h was also evaluated. We reviewed 39 prescriptions. About half of all prescriptions (51.3%) was found to be unnecessary due to misdiagnosis, 16 prescriptions (41%) were considered inappropriate (2 for inadequate duration and 14 for inappropriate spectrum of activity, mainly with ceftriaxone prescriptions (9 cases)). Ten prescriptions (25.6%) were re-assessed between 48 and 72 hours after treatment initiation. According to this study, an improvement program was implemented. A diagnostic algorithm for UTI in elderly was drafted and will be integrated into the local guidelines. A supporting document for the re-assessment of the prescriptions 48-72h after treatment initiation was created. We decided to perform an evaluation of antibiotic prescriptions by the subcutaneous route.

  6. Three-month evaluation of vital tooth bleaching using light units-a randomized clinical study.

    Science.gov (United States)

    Polydorou, O; Wirsching, M; Wokewitz, M; Hahn, P

    2013-01-01

    The aim of this study was to evaluate the color stability of vital bleaching using a halogen unit, laser, or only chemical activation up to three months after treatment. A total of 60 patients were divided into three groups, and their teeth were bleached with 38% hydrogen peroxide using three methods: acceleration of the bleaching process with halogen (eight minutes), laser (30 seconds), or chemical activation only. All teeth were bleached a maximum of four times (4 × 15 minutes) until a change of six shade tabs took place. The color was evaluated both visually and with a spectrophotometer before bleaching, immediately after bleaching, and one and three months after bleaching. Directly after bleaching, the use of halogen showed better results than laser (p≤0.05). One and three months after bleaching, no significant difference was found between the tested methods relative to the shade change, independent of the method of shade evaluation (p>0.05). As far as the color stability is concerned, bleaching with halogen resulted in stable color throughout the three months (p>0.05), whereas the other two methods resulted in whiter teeth after one and three months compared with the color directly after bleaching (p≤0.05). Bleaching with laser needed more time than halogen for the desired shade change (p≤0.05). Although directly after treatment bleaching with halogen resulted in better results, one and three months after bleaching the kind of acceleration used in the bleaching process did not have any effect on the esthetic results.

  7. Radioiodinated methyl-branched fatty acids: Evaluation of catabolites formed in vivo

    Energy Technology Data Exchange (ETDEWEB)

    Knapp, F.F. Jr.; Reske, S.N.; Kirsch, G.; Ambrose, K.R.; Blystone, S.L.; Goodman, M.M.

    1987-01-01

    Radioiodinated terminal iodophenyl-substituted long-chain fatty acids containing either racemic mono-methyl or geminal dimethyl-branching in the alkyl chain have been shown to exhibit delayed myocardial clearance properties which make these agents useful for the SPECT evaluation of myocardial fatty acid uptake patterns. Although the myocardial clearance rate of 15-(p-iodophenyl)-3-R,S- methylpentadecanoic acid (BMIPP) is considerably delayed, in comparison with the IPPA straight-chain analogue, analysis of the radioiodinated lipids present in the outflow tract of isolated rat hearts administered BMIPP have clearly demonstrated the presence of a polar metabolite. The synthesis of ..beta..-hydroxy fatty acids has been developed to allow investigation of the possible formation of ..beta..-hydroxy catabolites in vivo. The preparation of ..beta..-hydroxy BMIPP and ..beta..-hydroxy IPPA are described, and the possible significance of their formation in vivo discussed. 4 figs.

  8. Evaluation of the Iranian Mini Nutritional Assessment Short-Form in Community-dwelling Elderly

    Directory of Open Access Journals (Sweden)

    Aida Malek Mahdavi

    2015-07-01

    Full Text Available Background: This study was aimed to assess agreement and diagnostic accuracy of the Iranian version of Mini Nutritional Assessment short-form (MNA-SF against the original MNA, as a gold standard in community-dwelling elderly. Methods: The full MNA and 9-item MNA-SF comprising questions regarding clinical status, dietary assessment and self-perception of health status and nutri-tion together with mid-arm and calf circumference measurements without in-cluding the body mass index (BMI were completed for 205 volunteers aged 65 or older recruited from all over Markazi Province (Iran. Correlation, diagnostic accuracy and agreement between the MNA-SF and full MNA were calculated. Results: The MNA and the MNA-SF classified 45.4% and 64.4% of the sub-jects as malnourished or at risk of malnutrition, respectively. Substantial agree-ment between the MNA-SF and full MNA was observed (Kappa=0.633. The MNA-SF correlated strongly with the full MNA (r=0.868, P<0.001. The MNA-SF showed high sensitivity (96.77% and negative predictive values (95.89%, relatively high specificity (62.5% and positive predictive values (68.18% and fair accuracy (Area under curve =0.796. Conclusion: Iranian MNA-SF seems to be an applicable screening tool for quick detection of malnutrition or at risk of malnutrition in community-dwelling elderly especially when BMI is unavailable.

  9. An evaluation of the adhesion of solid oral dosage form coatings to the oesophagus.

    Science.gov (United States)

    Smart, John D; Dunkley, Sian; Tsibouklis, John; Young, Simon

    2015-12-30

    There is a requirement for the development of oral dosage forms that are adhesive and allow extended oesophageal residence time for localised therapies, or are non-adhesive for ease of swallowing. This study provides an initial assessment of the in vitro oesophageal retention characteristics of several widely utilised pharmaceutical coating materials. To this end, a previously described apparatus has been used to measure the force required to pull a coated disc-shaped model tablet across a section of excised oesophageal tissue. Of the materials tested, the well-studied mucoadhesive polymer sodium alginate was found to be associated with significant oesophageal adhesion properties that was capable of 'self-repairing'. Hydroxypropylmethylcellulose exhibited less pronounced bioadhesive behaviour and blending this with plasticiser or with low molecular weight polymers and surfactants did not significantly affect this. Low molecular weight water soluble polymers, were found to behave similarly to the uncoated glass control disc. Polysorbates exhibited bioadhesion behaviour that was majorly influenced by the nature of the surfactant. The insoluble polymer ethylcellulose, and the relatively lipophilic surfactant sorbitan monooleate were seen to move more readily than the uncoated disc, suggesting that these may have a role as 'easy-to-swallow' coatings.

  10. Emergy Evaluation of Formal Education in the United States: 1870 to 2011

    Directory of Open Access Journals (Sweden)

    Daniel E. Campbell

    2014-07-01

    Full Text Available We evaluated the education system of the United States from 1870 to 2011 using emergy methods. The system was partitioned into three subsystems (elementary, secondary and college/university education and the emergy inputs required to support each subsystem were determined for every year over the period of analysis. We calculated the emergy required to produce an individual with a given number of years of education by summing over the years of support needed to attain that level of education. In 1983, the emergy per individual ranged from 8.63E+16 semj/ind. for a pre-school student to 165.9E+16 semj/ind. for a Ph.D. with 2 years of postdoctoral experience. The emergy of teaching and learning per hour spent in this process was calculated as the sum of the emergy delivered by the education and experience of the teachers and the emergy brought to the process of learning by the students. The emergy of teaching and learning was about an order of magnitude larger than the annual emergy supporting the U.S. education system (i.e., the emergy inflows provided by the environment, energy and materials, teachers, entering students, goods and services. The implication is that teaching and learning is a higher order social process related to the development and maintenance of the national information cycle. Also, the results imply that there is a 10-fold return on the emergy invested in operating the education system of the United States.

  11. Evaluation of cyclosporine A eye penetration after administration of liposomal or conventional forms in animal model

    Directory of Open Access Journals (Sweden)

    Bizhan Malaekeh-Nikouei

    2013-01-01

    Full Text Available Abstract A lot of researches have investigated the effects of topical cyclosporine A on the eye surface layers’ diseases. By now the main limitation in cyclosporine application is the low permeation of the drug into the posterior segments of the eye. The aim of present study was to formulate high permeable dosage form can be beneficial in the topical treatment of the uveitis. To reach higher corneal drug absorption and drug concentration in the posterior segments of the eye, 3 nanoliposomal formulations containing 0.5 mg/ml cyclosporine A were prepared. Liposomal formulations and the commercial product (Restasis® were instilled in the right and left eyes of the rabbits, respectively. The rabbits were killed in the 3, 7, 14 and 28 days of study and the aqueous humor and vitreous were extracted. Mean size of liposomal formulation number 1, number 2 and number 3 were 107.2 ± 0.7, 129.3±0.9 and 144.8±1.8 nm and their zeta potential were -5.0±1.7, -5.5±2.3 and 44.6±6.2 mV, respectively. Results of ocular analysis showed that the liposomal formulations could increase the concentration of the drug in the aqueous and vitreous like Restasis®. But, in contrast with what has been expected the findings of this study implicate nanoliposomal formulations prepared could not make a significant difference in concentration of the drug in aqueous and vitreous humor compared to Restasis® (anionic microemulsion. In conclusion, we can state that liposomes with the same composition as our formulations are not more efficient than microemulsion for cyclosporine as ophthalmic drug delivery.

  12. Evaluation of cyclosporine A eye penetration after administration of liposomal or conventional forms in animal model

    Directory of Open Access Journals (Sweden)

    Sara Nikoofal-Sahlabadi

    2013-01-01

    Full Text Available Abstract A lot of researches have investigated the effects of topical cyclosporine A on the eye surface layers’ diseases. By now the main limitation in cyclosporine application is the low permeation of the drug into the posterior segments of the eye. The aim of present study was to formulate high permeable dosage form can be beneficial in the topical treatment of the uveitis. To reach higher corneal drug absorption and drug concentration in the posterior segments of the eye, 3 nanoliposomal formulations containing 0.5 mg/ml cyclosporine A were prepared. Liposomal formulations and the commercial product (Restasis® were instilled in the right and left eyes of the rabbits, respectively. The rabbits were killed in the 3, 7, 14 and 28 days of study and the aqueous humor and vitreous were extracted. Mean size of liposomal formulation number 1, number 2 and number 3 were 107.2 ± 0.7, 129.3±0.9 and 144.8±1.8 nm and their zeta potential were -5.0±1.7, -5.5±2.3 and 44.6±6.2 mV, respectively. Results of ocular analysis showed that the liposomal formulations could increase the concentration of the drug in the aqueous and vitreous like Restasis®. But, in contrast with what has been expected the findings of this study implicate nanoliposomal formulations prepared could not make a significant difference in concentration of the drug in aqueous and vitreous humor compared to Restasis® (anionic microemulsion. In conclusion, we can state that liposomes with the same composition as our formulations are not more efficient than microemulsion for cyclosporine as ophthalmic drug delivery.

  13. Development and Evaluation of Across-Unit Diagnostic Feedback Mechanism for Online Learning

    Science.gov (United States)

    Lin, Jian-Wei; Lai, Yuan-Cheng; Szu, Yu-Chin; Lai, Ching-Neng; Chuang, Yuh-Shy; Chen, Yen-Hung

    2014-01-01

    Solving well-structured problems often requires using considerable related concepts which are usually scattered and introduced throughout different learning units of a subject. In addition, poor learning of related concepts of preceding units may block the learning of subsequent units, and eventually leads to the inability to solve well-structured…

  14. FORMULATION DEVELOPMENT AND EVALUATION OF COLON TARGETED DOSAGE FORM OF IBUPROFEN

    Directory of Open Access Journals (Sweden)

    Guru Sharan

    2012-01-01

    Full Text Available Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn’s disease, ulcerative colitis, irritable bowel syndrome but also for the potential it holds for the systemic delivery of proteins and therapeutic peptides. The aim of the study was to develop colon targeted film coated tablets of Ibuprofen using HPMC K4M, Eudragit L100, and Ethyl cellulose as carriers. All the formulations (F1 to F6 were evaluated for the physicochemical parameters and were subjected to in vitro drug release studies. The amount of Ibuprofen released from tablets atdifferent time intervals was estimated by UV spectrophotometer. The formulation F6 released 98.34 % of Ibuprofen. The results of the study showed that formulation F6 is most likely to provide targeting of Ibuprofen for local action in the colon owing to its minimal release of the drug in the first 5 h. The results of the presentstudy have demonstrated that the film coated tablet system is a promising vehicle for preventing rapid hydrolysis in gastric environment and improving oral bioavailability of Ibuprofen for the treatment of disease of colon region.

  15. The adjusting mining technology of combining fully mechanized with individual prop, rotating, hilt, irregular form, and double unit face on thin coal seam of Tianchen Mine

    Institute of Scientific and Technical Information of China (English)

    SONG Hua-ling; WEN Guo-feng; LI Jin-ke

    2008-01-01

    Analyzed the situations and characteristics of thin coal seam mining and its mining technologies, and introduced the mining innovation technology used by Tianchen Coal Mine of Zhaozhuang Coal Company of China. This innovation technology combined the fully mechanized mining with individual props, and the working face of mining is over length, irregular form and double units. The rotational adjusting mining technology on thin coal seam is also practiced in this new mining technology. The detail technologies, such as outlays of working face and ways, mining methods, equipments of cutting, transporting and sporting, have been introduced. So that, using the synthetic and creative mining tech-nologies, Tianchen Coal Mine solves the mining problems of thin coal seam successfully.

  16. Becoming Overweight Without Gaining a Pound: Weight Evaluations and the Social Integration of Mexicans in the United States.

    Science.gov (United States)

    Altman, Claire E; Van Hook, Jennifer; Gonzalez, Jonathan

    2017-01-01

    Mexican women gain weight with increasing duration in the United States. In the United States, body dissatisfaction tends to be associated with depression, disordered eating, and incongruent weight evaluations, particularly among white women and women of higher socioeconomic status. However, it remains unclear how overweight and obesity is interpreted by Mexican women. Using comparable data of women ages 20-64 from both Mexico (the 2006 Encuesta Nacional de Salud y Nutricion; N=17,012) and the United States (the 1999-2009 National Health and Nutrition Examination Surveys; N=8,487), we compare weight status evaluations among Mexican nationals, Mexican immigrants, U.S.-born Mexicans, U.S.-born non-Hispanic Whites, and U.S.-born non-Hispanic blacks. Logistic regression analyses, which control for demographic and social-economic variables and measured body mass index and adjust for the likelihood of migration for Mexican nationals, indicate that the tendency to self-evaluate as overweight among Mexicans converges with levels among non-Hispanic whites and diverges from blacks over time in the United States. Overall, the results suggest a U.S. integration process in which Mexican-American women's less critical self-evaluations originate in Mexico but fade with time in the United States as they gradually adopt U.S. white norms for thinner body sizes. These results are discussed in light of social comparison and negative health assimilation.

  17. Evaluation of Antimicrobial and Antifungal efficacy of Chitosan as endodontic irrigant against Enterococcus Faecalis and Candida Albicans Biofilm formed on tooth substrate.

    Science.gov (United States)

    Yadav, Pankaj; Chaudhary, Sarika; Saxena, Rajendra K; Talwar, Sangeeta; Yadav, Sudha

    2017-03-01

    Bacterial biofilms formed on the root canal wall are often difficult to remove. This study aimed to evaluate the cytotoxic effect and antibacterial efficacy of chitosan when used as root canal irrigant against E. Faecalis and Candida albicans biofilm formed on tooth substrate. The present study evaluated antibacterial effect of 0.25% Chitosan, 0.5% Chitosan, 2% chlorhexidine and 3% sodium hypochlorite against Enterococcus faecalis and Candida Albicans. Agar-well diffusion methods, minimal inhibitory concentration tests and biofilm susceptibility assays were used to determine antibacterial activity. Teeth specimens were sectioned to obtain a standardized tooth length of 12mm. Specimens were inoculated with 10 mL of the freshly prepared E. Faecalis suspension and Candida albicans for 4 weeks. The specimens were then instrumented with ProTaper rotary files F3 size. After irrigation with test solution, three sterile paper points were placed into one canal, left for 60 s and transferred to a test tube containing 1 mL of reduced transport fluid. The number of CFU in 1 mL was determined. 3-week biofilm qualitative assay showed complete inhibition of bacterial growth with 3% Sodium hypochlorite, 2% Chlorhexidine and Chitosan except saline, which showed presence of bacterial growth. Significant reduction of colony forming units (CFU)/mL was observed for the chitosan groups and the antibacterial activity of the chitosan groups was at par with 3% NaOCl and 2% Chlorhexidine. It was observed that the chitosan showed no cytotoxicity at 3mg/ml and 10% cytotoxicity at 6mg/ml. The use of chitosan as a root canal irrigant might be an alternative considering the various undesirable properties of NaOCl and chlorhexidine. Key words:Biofilm, Candida albicans, Chitosan, Cytotoxicity, Enterococcus faecalis.

  18. Evaluation of Antimicrobial and Antifungal efficacy of Chitosan as endodontic irrigant against Enterococcus Faecalis and Candida Albicans Biofilm formed on tooth substrate

    Science.gov (United States)

    Yadav, Pankaj; Saxena, Rajendra K.; Talwar, Sangeeta; Yadav, Sudha

    2017-01-01

    Background Bacterial biofilms formed on the root canal wall are often difficult to remove. This study aimed to evaluate the cytotoxic effect and antibacterial efficacy of chitosan when used as root canal irrigant against E. Faecalis and Candida albicans biofilm formed on tooth substrate. Material and Methods The present study evaluated antibacterial effect of 0.25% Chitosan, 0.5% Chitosan, 2% chlorhexidine and 3% sodium hypochlorite against Enterococcus faecalis and Candida Albicans. Agar-well diffusion methods, minimal inhibitory concentration tests and biofilm susceptibility assays were used to determine antibacterial activity. Teeth specimens were sectioned to obtain a standardized tooth length of 12mm. Specimens were inoculated with 10 mL of the freshly prepared E. Faecalis suspension and Candida albicans for 4 weeks. The specimens were then instrumented with ProTaper rotary files F3 size. After irrigation with test solution, three sterile paper points were placed into one canal, left for 60 s and transferred to a test tube containing 1 mL of reduced transport fluid. The number of CFU in 1 mL was determined. Results 3-week biofilm qualitative assay showed complete inhibition of bacterial growth with 3% Sodium hypochlorite, 2% Chlorhexidine and Chitosan except saline, which showed presence of bacterial growth. Significant reduction of colony forming units (CFU)/mL was observed for the chitosan groups and the antibacterial activity of the chitosan groups was at par with 3% NaOCl and 2% Chlorhexidine. It was observed that the chitosan showed no cytotoxicity at 3mg/ml and 10% cytotoxicity at 6mg/ml. Conclusions The use of chitosan as a root canal irrigant might be an alternative considering the various undesirable properties of NaOCl and chlorhexidine. Key words:Biofilm, Candida albicans, Chitosan, Cytotoxicity, Enterococcus faecalis. PMID:28298975

  19. Pharmacokinetic evaluation of a new oral sustained release dosage form of tramadol

    Science.gov (United States)

    Malonne, H; Sonet, B; Streel, B; Lebrun, S; De Niet, S; Sereno, A; Vanderbist, F

    2004-01-01

    Aims To compare the pharmacokinetic profile of a new modified release formulation of tramadol (Tramadol LP 200 mg, SMB Technology, Marche-en-Famenne, Belgium) with that of an immediate release capsule (Topalgic® 50 mg, Grünenthal, Aachen, Germany) after single and multiple dosing and to assess the potential effect of food on its relative bioavailability. Methods The first study had an open, single-dose, three-treatment, three-period, six-sequence, randomised, crossover design with at least a five-day wash-out. The second study had an open, steady-state, two-treatment, two-period, two-sequence, randomised crossover design with at least a seven-day wash-out. Both studies contained 30 healthy subjects. Both enantiomers of tramadol and O-demethyl-tramadol (the only active metabolite of tramadol) were assayed in the plasma using an LC-MS/MS method. AUC∞, AUCt, Cmax, Tmax, and T1/2 were estimated. Statistical analysis was performed using univariate anova, the Wilcoxon nonparametric method or Friedman's nonparametric anova where appropriate. Results Tramadol had a significantly lower Cmax and longer Tmax than the conventional formulation. Thus, the mean (± sd) Cmax of tramadol were 646 ± 192 and 300 ± 94 ng ml−1 for Topalgic® 4 × 50mg and Tramadol LP 200 mg, respectively (95% confidence interval on the difference expressed as a percentage 42–51). AUC of tramadol from both formulations was comparable (similar AUC∞ and AUCt). Thus, the mean AUC∞ of (+/–)tramadol obtained after multiple dosing were 4611 ± 1944 and 5105 ± 2101 ngh ml−1 after Topalgic® 4 × 50mg and Tramadol LP 200 mg, respectively (95%CI 102–123%). We also demonstrate that the pharmacokinetics of the drug are not influenced by the intake of food. Thus, the mean AUC∞ of (+/–) tramadol were 5444 ± 1637 and 5169 ± 1580 ngh ml−1 after Tramadol LP 200 mg given in the fasting and fed states, respectively (95%CI = 88–103%). Conclusions The new sustained release form of tramadol

  20. Dynamic evaluation of two decades of WRF-CMAQ ozone simulations over the contiguous United States

    Science.gov (United States)

    Astitha, Marina; Luo, Huiying; Rao, S. Trivikrama; Hogrefe, Christian; Mathur, Rohit; Kumar, Naresh

    2017-09-01

    Dynamic evaluation of the fully coupled Weather Research and Forecasting (WRF)- Community Multi-scale Air Quality (CMAQ) model ozone simulations over the contiguous United States (CONUS) using two decades of simulations covering the period from 1990 to 2010 is conducted to assess how well the changes in observed ozone air quality are simulated by the model. The changes induced by variations in meteorology and/or emissions are also evaluated during the same timeframe using spectral decomposition of observed and modeled ozone time series with the aim of identifying the underlying forcing mechanisms that control ozone exceedances and making informed recommendations for the optimal use of regional-scale air quality models. The evaluation is focused on the warm season's (i.e., May-September) daily maximum 8-hr (DM8HR) ozone concentrations, the 4th highest (4th) and average of top 10 DM8HR ozone values (top10), as well as the spectrally-decomposed components of the DM8HR ozone time series using the Kolmogorov-Zurbenko (KZ) filter. Results of the dynamic evaluation are presented for six regions in the U.S., consistent with the National Oceanic and Atmospheric Administration (NOAA) climatic regions. During the earlier 11-yr period (1990-2000), the simulated and observed regional average trends are not statistically significant. During the more recent 2000-2010 period, all observed trends are statistically significant and WRF-CMAQ captures the observed downward trend in the Southwest and Midwest but under-predicts the downward trends in observations for the other regions. Observational analysis reveals that it is the magnitude of the long-term forcing that dictates the maximum ozone exceedance potential; there is a strong linear relationship between the long-term forcing and the 4th highest or the average of the top10 ozone concentrations in both observations and model output. This finding indicates that improving the model's ability to reproduce the long-term component

  1. An Evaluation and Ranking of Children’s Hospital Websites in the United States

    Science.gov (United States)

    Walker, Daniel M; Ford, Eric W

    2016-01-01

    Background Children’s hospitals are faced with the rising need for technological innovation. Their prospective health care consumers, who increasingly depend on the Web and social media for communication and consumer engagement, drive this need. As patients and family members navigate the Web presence of hospitals, it is important for these specialized organizations to present themselves and their services efficiently. Objective The purpose of this study was to evaluate the website content of children’s hospitals in order to identify opportunities to improve website design and create benchmarks to judge improvement. Methods All websites associated with a children’s hospital were identified using a census list of all children’s hospitals in the United States. In March of 2014, each website and its social media were evaluated using a Web crawler that provided a 5-dimensional assessment that included website accessibility, marketing, content, technology, and usability. The 5-dimensional assessment was scored on a scale ranging from 0 to 10 with positive findings rated higher on the scale. Websites were ranked by individual dimensions as well as according to their average ranking across all dimensions. Results Mean scores of 153 websites ranged from 5.05 to 8.23 across all 5 dimensions. Results revealed that no website scored a perfect 10 on any dimension and that room exists for meaningful improvement. Conclusions Study findings allow for the establishment of baseline benchmarks for tracking future website and social media improvements and display the need for enhanced Web-based consumer engagement for children’s hospitals. PMID:27549074

  2. Evaluating and monitoring analgesia and sedation in the intensive care unit.

    Science.gov (United States)

    Sessler, Curtis N; Grap, Mary Jo; Ramsay, Michael Ae

    2008-01-01

    Management of analgesia and sedation in the intensive care unit requires evaluation and monitoring of key parameters in order to detect and quantify pain and agitation, and to quantify sedation. The routine use of subjective scales for pain, agitation, and sedation promotes more effective management, including patient-focused titration of medications to specific end-points. The need for frequent measurement reflects the dynamic nature of pain, agitation, and sedation, which change constantly in critically ill patients. Further, close monitoring promotes repeated evaluation of response to therapy, thus helping to avoid over-sedation and to eliminate pain and agitation. Pain assessment tools include self-report (often using a numeric pain scale) for communicative patients and pain scales that incorporate observed behaviors and physiologic measures for noncommunicative patients. Some of these tools have undergone validity testing but more work is needed. Sedation-agitation scales can be used to identify and quantify agitation, and to grade the depth of sedation. Some scales incorporate a step-wise assessment of response to increasingly noxious stimuli and a brief assessment of cognition to define levels of consciousness; these tools can often be quickly performed and easily recalled. Many of the sedation-agitation scales have been extensively tested for inter-rater reliability and validated against a variety of parameters. Objective measurement of indicators of consciousness and brain function, such as with processed electroencephalography signals, holds considerable promise, but has not achieved widespread implementation. Further clarification of the roles of these tools, particularly within the context of patient safety, is needed, as is further technology development to eliminate artifacts and investigation to demonstrate added value.

  3. Technical-Economic Evaluation of a Cogeneration Unit Considering Carbon Emission Savings

    Directory of Open Access Journals (Sweden)

    Ana Christina Ferreira

    2014-06-01

    Full Text Available The support of combined heat and power production systems has gained policy attention, because these are often considered to be less polluting and more efficient than conventional energy conversion systems. As a consequence, the potential market for these energy systems that contribute to reduce greenhouse gas emissions and to enhance energy security on a national level, is shifting from large-scale existing units to small and micro-size emerging technologies. This paper presents a numerical model based on a cost-benefit analysis used to design an optimal cogeneration system for a small-scale building application, considering the Portuguese context and the comparison with the harmonized efficiency reference values for the separate production of electricity and useful heat. The model includes the identification of the objective function terms (i.e., the elements involved in the financial analysis across the system lifetime and the economic evaluation of costs and benefits of the combined heat and power production system. The economic viability of cogeneration systems significantly depends on system technology, client energy requirements and support schemes implemented in the respective countries. A strategic approach is necessary to adequately embed the new technology as a feasible solution in terms of investment and operational costs. Only by matching the energy supply to the needs and expectations of the energy users, it will be possible to improve the market competitiveness of these alternative power production plants. The optimal solution disclosed a positive annual worth, which is higher if the carbon emission savings are monetized. In addition, the optimal system represents a more efficient way to produce useful heat and electricity (i.e. a positive primary energy saving and to reduce gas emissions. A cost-benefit analysis can be applied for the techno-economic evaluation of a CHP system by assessing the monetary socio-environmental costs

  4. A Population-based Evaluation of Cervical Screening in the United States: 2008–2011

    Science.gov (United States)

    Cuzick, Jack; Myers, Orrin; Hunt, William C.; Robertson, Michael; Joste, Nancy E.; Castle, Philip E.; Benard, Vicki B.; Wheeler, Cosette M.

    2014-01-01

    Background Cervical screening consumes substantial resources, but little is known about utilization in the United States or compliance with guideline recommendations. Methods To describe population screening coverage, utilization and outcomes and examine time trends from 2008 to 2011, cervical cytology reports from women residing in New Mexico (981,063 tests from 511,381 women) were evaluated. Results From 2008–2011 cervical screening utilization decreased at all ages, but especially in younger women, with a two-thirds reduction at ages 15–20 years. 94% of women aged 25–29 years were screened within 48 months but coverage decreased at older ages, to 69% at 45–49 years and 55% at 60–64 years. Intervals between screening tests were significantly longer in 2011 compared to 2008 (hazard ratio = 1.23, 95% CI = 1.22–1.24) although the commonest rescreening interval was 13 months. In 2011, 91.9% of screening tests for women aged 21–65 years were negative, 6.6% showed minor abnormalities, and 1.0% high grade abnormalities.. High grade abnormality rates were relatively constant over time, but minor abnormalities and atypical cells cannot rule out high-grade (ASC-H) were increasing. Conclusion This population-based evaluation of cervical screening shows high coverage under the age of 40 years but lower levels in older women. Screening under age 21 years is becoming less common and screening intervals are lengthening, reflecting updates in national screening guidelines. Impact Assessment of cervical screening intervals and population outcomes is essential for accurately estimating the impact and effectiveness of changing recommendations and vaccination against human papillomavirus infections. PMID:24302677

  5. Strengthening the nursing and midwifery unit manager role: an interim programme evaluation.

    Science.gov (United States)

    Clarke, Elizabeth; Diers, Donna; Kunisch, Judith; Duffield, Christine; Thoms, Debra; Hawes, Sue; Stasa, Helen; Fry, Margaret

    2012-01-01

    An interim evaluation was conducted on the professional development components of the New South Wales (NSW) Health 'take the lead' ('ttl') programme, an initiative aimed at enhancing nursing/midwifery unit managers' (N/MUM) skills. Previous research has highlighted the importance of strong nurse leaders, and shown that training programmes may assist in improving leadership skills. The NSW Nursing and Midwifery Office (NaMO) developed the 'ttl' programme for N/MUMs with the intention of improving hospital quality by strengthening nurse leadership. The programme had three strands, with the professional development modules a key component. Semi-structured interviews were conducted with 17 participants who had completed components of the 'ttl' programme. The interviews explored participants' perceptions of the programme, and suggestions for improvement. Qualitative analysis was conducted on the transcribed interviews. The N/MUMs reported feeling increasingly empowered, knowledgeable and supported as a result of attending the 'ttl' workshops. The results suggest that the studied components of the 'ttl' programme may be effective in assisting nurse leaders gain new leadership skills and institute positive changes in the nursing work environment. Leadership programmes such as 'ttl' may provide an effective tool for improving N/MUM performance and role confidence. © 2011 Blackwell Publishing Ltd.

  6. Evaluation of the knowledge regarding prevention of cervical cancer among women from a Health Unit

    Directory of Open Access Journals (Sweden)

    Ernandes Gonçalves Dias

    2015-07-01

    Full Text Available Background and objectives: Cervical cancer is a disease with high degree of morbidity and mortality, but has early detection by performing screening test which allows healing. This study aimed to evaluate the knowledge regarding prevention of Cervical Cancer among women in a Basic Health Unit in Minas Gerais. Methods: This is a study descriptive with approach qualitative with 44 women. Was used as the data collection instrument of a semistructured script consisting of subjective questions. Data were collected between March April 2014. Results: The women had age of 40-57 years old, 33 (75% were married, 43(97,73% had children, 20 (45,45% had incomplete primary education, 36 (81,82% were responsible for all financial income of the family and lived with up to the minimum wage. As for the Pap smear, considered important, however showed little clarity as to the meaning of prevention. Performed the test as means of prevention and early diagnosis of Cervical Cancer. Among women who did not perform the preventive the cause was discouragement. Conclusion: We conclude that although the Pap smear be offered for free, there is still women who do not have adequate knowledge about the same and not makes periodically, fitting to health services intensify health education programs to seeking to raise awareness about the importance of regular practice of the Pap smear. Keywords: Cervix Uteri. Uterine Cervical Neoplasms. Health centers.

  7. An evaluation of clinical pharmacist service on a neurology care unit.

    Science.gov (United States)

    Yi, Zhan-Miao; Sun, Shu-Sen; Li, Xiao-Xiao; Lu, Ming; Zhai, Suo-Di

    2016-02-01

    Medications used to treat neurological diseases may result in adverse effects. Research is needed to demonstrate pharmacist value and their roles in patient care. To categorize the types and severities of the prescribing errors intercepted and to describe clinical activities conducted by neurology ward pharmacists. Pharmacists prospectively reviewed medication orders over an 18-month period with inventions documented and categorized. A total of 341 prescribing errors in 1183 patients were intercepted. The most common error types were dosing frequency (35.8 %) and medication selection (21.5 %). The top five most detected error medications were those indicated for hyperhomocysteinemia (22.0 %), stress ulcer prophylaxis (12.3 %), poor circulation (10.9 %), hyperglycemia (6.5 %), and infections (5.9 %). Although 67.5 % of the detected errors having the potential causing no harm, 26.4 % of the errors may require intervention, and 6.2 % may increase the length of stay. The number of errors decreased from 19 to 10 per month during the study period. Clinical pharmacists also actively engaged in medication use evaluation, clinical decision support system optimization, and education to patients and providers. Presence of clinical pharmacists at the neurology unit may help in early detection of prescribing errors with increased patient safety.

  8. An Evaluation of Emergency Preparedness of Local Government Unit on National Calamities

    Directory of Open Access Journals (Sweden)

    ROME B. MORALISTA

    2014-02-01

    Full Text Available This descriptive survey method was used to evaluate the Emergency Preparedness practices of Local Government Unit Municipality of Calinog on the National Calamities specifically the Typhoon Haiyan hit the town last November 8, 2013. The findings revealed that in preparing for the storm, the respondents preferred to contact a local geologist or country planning department; in making sure the family knows the name, address, and phone number of the contact person, they prefer to post emergency phone numbers at every phone; during flood watch and warning, the respondents preferred to gather the emergency supplies you previously stocked in your home and stay tuned to local radio or television station for updates; when it comes to an emergency supplies at home, the respondents have several cleaned containers of water, large enough for a 3-5 day supply of water; in preparing to evacuate, they prefer to fill their vehicle’s gas tank and make sure the emergency kit for their car is ready. Finally, when ordered to evacuate, the respondents preferred to take only essential items.

  9. Evaluation of Waste Anesthetic Gas in the Postanesthesia Care Unit within the Patient Breathing Zone

    Science.gov (United States)

    Hiller, Kenneth N.; Altamirano, Alfonso V.; Cai, Chunyan; Tran, Stephanie F.; Williams, George W.

    2015-01-01

    Potential health hazards from waste anesthetic gases (WAGs) have been a concern since the introduction of inhalational anesthetics into clinical practice. The potential to exceed recommended exposure levels (RELs) in the postanesthesia care unit (PACU) exists. The aim of this pilot study was to assess sevoflurane WAG levels while accounting for factors that affect inhalational anesthetic elimination. In this pilot study, 20 adult day surgery patients were enrolled with anesthesia maintained with sevoflurane. Following extubation, exhaled WAG from the patient breathing zone was measured 8 inches from the patient's mouth in the PACU. Maximum sevoflurane WAG levels in the patient breathing zone exceeded National Institute for Occupational Safety and Health (NIOSH) RELs for every 5-minute time interval measured during PACU Phase I. Observed WAGs in our study were explained by inhalational anesthetic pharmacokinetics. Further analysis suggests that the rate of washout of sevoflurane was dependent on the duration of anesthetic exposure. This study demonstrated that clinically relevant inhalational anesthetic concentrations result in sevoflurane WAG levels that exceed current RELs. Evaluating peak and cumulative sevoflurane WAG levels in the breathing zone of PACU Phase I and Phase II providers is warranted to quantify the extent and duration of exposure. PMID:26693222

  10. Enhancing quality and safety competency development at the unit level: an initial evaluation of student learning and clinical teaching on dedicated education units.

    Science.gov (United States)

    Mulready-Shick, Joann; Kafel, Kathleen W; Banister, Gaurdia; Mylott, Laura

    2009-12-01

    The need to attend to quality and safety competency development, increase capacity in nursing education programs, address the faculty and nursing shortages, and find new ways to keep step with an ever-changing health care environment has brought forth numerous creative curricular responses and collaborative efforts. To tackle these multiple needs and challenges simultaneously, a new academic-service partnership was created to collaboratively develop an innovative clinical education delivery model. The designed dedicated education unit model not only promoted student learning about quality and safety competencies via unit-based projects but also supported quality improvements in nursing care delivery. Following the initial semester of the model's implementation, a pilot study was conducted. The findings generated the evidence required to take this innovation to the next level. Moreover, the education-practice partnership, which was created to implement the clinical education delivery model, was strengthened as a result of this preliminary evaluation.

  11. Evaluation of the Synthoil process. Volume III. Unit block flow diagrams for a 100,000 barrel/stream day facility

    Energy Technology Data Exchange (ETDEWEB)

    Salmon, R.; Edwards, M.S.; Ulrich, W.C.

    1977-06-01

    This volume consists of individual block flowsheets for the various units of the Synthoil facility, showing the overall flows into and out of each unit. Material balances for the following units are incomplete because these are proprietary processes and the information was not provided by the respective vendors: Unit 24-Claus Sulfur Plant; Unit 25-Oxygen Plant; Unit 27-Sulfur Plant (Redox Type); and Unit 28-Sour Water Stripper and Ammonia Recovery Plant. The process information in this form was specifically requested by ERDA/FE for inclusion in the final report.

  12. Completion Report for Model Evaluation Well ER-11-2: Corrective Action Unit 98: Frenchman Flat

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Underground Test Area and Boreholes Programs and Operations

    2013-01-22

    Model Evaluation Well ER-11-2 was drilled for the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office in support of Nevada Environmental Management Operations at the Nevada National Security Site (formerly known as the Nevada Test Site). The well was drilled in August 2012 as part of a model evaluation program in the Frenchman Flat area of Nye County, Nevada. The primary purpose of the well was to provide detailed geologic, hydrogeologic, chemical, and radionuclide data that can be used to test and build confidence in the applicability of the Frenchman Flat Corrective Action Unit flow and transport models for their intended purpose. In particular, this well was designed to provide data to evaluate the uncertainty in model forecasts of contaminant migration from the upgradient underground nuclear test PIN STRIPE, conducted in borehole U-11b in 1966. Well ER-11-2 will provide information that can be used to refine the Phase II Frenchman Flat hydrostratigraphic framework model if necessary, as well as to support future groundwater flow and transport modeling. The main 31.1-centimeter (cm) hole was drilled to a total depth of 399.6 meters (m). A completion casing string was not set in Well ER-11-2. However, a piezometer string was installed in the 31.1-cm open hole. The piezometer is composed of 7.3-cm stainless-steel tubing hung on 6.0-cm carbon-steel tubing via a crossover sub. The piezometer string was landed at 394.5 m, for monitoring the lower tuff confining unit. Data collected during and shortly after hole construction include composite drill cuttings samples collected every 3.0 m, various geophysical logs, water quality (including tritium and other test-related radionuclides) measurements, and water level measurements. The well penetrated 42.7 m of Quaternary and Tertiary alluvium and 356.9 m of Tertiary volcanic rock. The water-level measured in the piezometer string on September 25, 2012, was 353.8 m below ground surface. No

  13. Evaluating ergonomic risk factors in non-regulated stone carving units of Jaipur.

    Science.gov (United States)

    Mukhopadhyay, Prabir; Srivastava, Saurabh

    2010-01-01

    Stone carving at Jaipur in Rajasthan state of India, is a traditional craft employing a large number of local youths. As an unorganized sector problems are many ranging from lack of benefits to occupational ergonomic issues of Work Related Musculoskeletal Disorders(WMSDs) and injury to body parts. Twenty five male workers were selected in each of the three sections of a stone carving unit. The focus was to identify different ergonomic risk factors associated in this profession from the field. Still photography and video photography was used to record different activities. Different types of non invasive tools like Rapid Entire Body Assessment (REBA), Rapid Upper Limb Assessment (RULA), Occupational Repetitive Action Index (OCRA) were used. Psychophysical measures were investigated by Body part discomfort map, rated perceived exertion scale and visual analogue scale. Objective measurements (heart arte and skin temperature) were recorded with stop watch and digital thermometer. The working heart rate after 30 minutes of work was 112.4 beats per minute categorizing the work as moderately heavy. Postural analysis by REBA indicated high score (13/13). Similarly postural analysis by RULA showed high score (7/7). These indicate vulnerability of many of the postures to musculoskeletal disorders and injury. The study indicates that majority of the activities are in the high risk category and demands immediate ergonomic intervention in the form of tool, workstation and process design. This could be done by involving different Non Government Organizations (NGOs), political parties, and the Human Rights Department both at the center and at the state level.

  14. Analysis of midwifery students' written reflections to evaluate progression in learning during clinical practice at birthing units.

    OpenAIRE

    Persson, Eva-Kristina; Kvist, LInda; Ekelin, Maria

    2015-01-01

    Written daily reflections during clinical practice on birthing units have been used during several years in midwifery education at Lund University, Sweden. However, the usefulness of these reflections for evaluation of progression in learning and professional development of students has to date not been evaluated. In order to analyse written reflections, two taxonomies developed by Bloom and Pettersen have been applied to the texts. Progression in the professional development of midwifery stu...

  15. Evaluation of Initial Telomere Length and Changes after Transplantation in Adult Double-Unit Cord Blood Transplant Recipients.

    Science.gov (United States)

    Ashbridge, Beth; Zehir, Ahmet; Lubin, Marissa; Barker, Juliet N; Moore, Malcolm A S

    2015-07-01

    Cord blood (CB) leukocytes have inherent telomere length (TL) variation, and CB hematopoietic stem cells (HSC) can maintain high telomerase levels preventing telomere attrition in vitro. We evaluated TL changes in 13 adult double-unit CB transplant (CBT) recipients. In the 26 units, we observed a marked variation in CB TL at thaw (median, 9.99 kilobases [kb]; range, 6.85 to 13.5). All 13 patients engrafted. Of 11 engrafting with 1 unit, there was no correlation between unit dominance and TL (mean dominant unit TL, 8.84 kb ± 1.76; mean nonengrafting unit TL, 10.3 kb ± 1.81; P = .77). Serial measurements of TL up to 1 year after CBT demonstrated an overall mean 3.04 kb ± .16 TL decrease with only 1 patient exhibiting telomere maintenance. In summary, initial TL does not predict CB unit dominance. Moreover, our analysis suggests neonatal hematopoiesis makes a transition to an HSC characterized by changes in average TL and potentially low telomerase asymmetric cell division in adult CBT recipients. Further investigation of alterations in telomere length and its clinical implications after transplantation of this observation are indicated.

  16. Planning for people? An evaluation of objectives for managing visitors at wildlife refuges in the United States

    Science.gov (United States)

    Jeffrey J. Brooks; Robert Massengale

    2011-01-01

    This study evaluates the quality of planning objectives for visitor services as written in Comprehensive Conservation Plans for the National Wildlife Refuge System of the United States. Planners in the U.S. Fish and Wildlife Service are predominantly writing public use objectives that address wildlife recreation and education. Results indicate that planners are writing...

  17. Effects of an SWH Approach and Self-Evaluation on Sixth Grade Students' Learning and Retention of an Electricity Unit

    Science.gov (United States)

    Memis, Esra Kabatas; Seven, Sabriye

    2015-01-01

    The purpose of this study is to explore the effects of guided, inquiry-based laboratory activities using the Science Writing Heuristic (SWH) approach and self-evaluation on students' science achievement. The study involved three sixth grade classes studying an electricity unit taught by the same primary school teacher. Before the study began, one…

  18. Overview of School and Unit Variables and Their Structural Relations in Phase I of the IGE Evaluation.

    Science.gov (United States)

    Price, Gary G.; And Others

    This document provides an overview of the school variables and unit variables used in Phase 1 of the Individually Guided Education (IGE) evaluation. Included in the discussion of each variable are a verbal definition of the variable, a description of the distribution of the variable in the 156 schools that participated in the Phase 1 study, and…

  19. Effects of an SWH Approach and Self-Evaluation on Sixth Grade Students' Learning and Retention of an Electricity Unit

    Science.gov (United States)

    Memis, Esra Kabatas; Seven, Sabriye

    2015-01-01

    The purpose of this study is to explore the effects of guided, inquiry-based laboratory activities using the Science Writing Heuristic (SWH) approach and self-evaluation on students' science achievement. The study involved three sixth grade classes studying an electricity unit taught by the same primary school teacher. Before the study began, one…

  20. Addressing Adolescent Depression in Schools: Evaluation of an In-Service Training for School Staff in the United States

    Science.gov (United States)

    Valdez, Carmen R.; Budge, Stephanie L.

    2012-01-01

    This study evaluated an adolescent depression in-service training for school staff in the United States. A total of 252 school staff (e.g., teachers, principals, counselors) completed assessments prior to and following the in-service and a subsample of these staff participated in focus groups following the in-service and three months later.…

  1. Intrahepatic and hilar mass-forming cholangiocarcinoma: Qualitative and quantitative evaluation with diffusion-weighted MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Fattach, Hassan El, E-mail: hassangreenmed@gmail.com [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Dohan, Anthony, E-mail: anthony.dohan@lrb.aphp.fr [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Université Paris-Diderot, Sorbonne Paris Cité, 10 Avenue de Verdun, 75010 Paris (France); UMR INSERM 965-Paris 7 “Angiogenèse et recherche translationnelle”, 2 rue Amboise Paré, 75010 Paris (France); Guerrache, Youcef, E-mail: docyoucef05@yahoo.fr [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Dautry, Raphael, E-mail: raphael.dautry@lrb.aphp.fr [Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris (France); Université Paris-Diderot, Sorbonne Paris Cité, 10 Avenue de Verdun, 75010 Paris (France); and others

    2015-08-15

    Highlights: • DW-MR imaging helps depicts all intrahepatic or hilar mass-forming cholangiocarcinomas. • DW-MRI provides best conspicuity of intrahepatic or hilar mass-forming cholangiocarcinomas than the other MRI sequences (P < 0.001). • The use of normalized ADC using the liver as reference organ results in the most restricted distribution of ADC values of intrahepatic or hilar mass-forming cholangiocarcinomas (variation coefficient = 16.6%). - Abstract: Objective: To qualitatively and quantitatively analyze the presentation of intrahepatic and hilar mass-forming cholangiocarcinoma with diffusion-weighted magnetic resonance imaging (DW-MRI). Materials and methods: Twenty-eight patients with histopathologically proven mass-forming cholangiocarcinoma (hilar, n = 17; intrahepatic, n = 11) underwent hepatic DW-MRI at 1.5-T using free-breathing acquisition and three b-values (0,400,800 s/mm{sup 2}). Cholangiocarcinomas were evaluated qualitatively using visual analysis of DW-MR images and quantitatively with conventional ADC and normalized ADC measurements using liver and spleen as reference organs. Results: All cholangiocarcinomas (28/28; 100%) were visible on DW-MR images. DW-MRI yielded best conspicuity of cholangiocarcinomas than the other MRI sequences (P < 0.001). Seven cholangiocarcinomas (7/11; 64%) showed hypointense central area on DW-MR images. Conventional ADC value of cholangiocarcinomas (1.042 × 10{sup −3} mm{sup 2}/s ± 0.221 × 10{sup −3} mm{sup 2}/s; range: 0.616 × 10{sup −3} mm{sup 2}/s to 2.050 × 10{sup −3} mm{sup 2}/s) was significantly lower than that of apparently normal hepatic parenchyma (1.362 × 10{sup −3} mm{sup 2}/s ± 0.187 × 10{sup −3} mm{sup 2}/s) (P < 0.0001), although substantial overlap was found. No significant differences in ADC and normalized ADC values were found between intrahepatic and hilar cholangiocarcinomas. The use of normalized ADC using the liver as reference organ resulted in the most restricted

  2. Evaluating quality of care using modular nursing on a multispecialty unit.

    Science.gov (United States)

    Bechtel, G A; Printz, V

    1994-03-01

    The purpose of this study was to examine performance outcome measures of nurses who work on a general medical unit and those who work on specialized or modular units. A sample of 82 nurses were reassigned to patients in either specialty modules or a general medical unit. Findings suggest that large nursing units staffed according to modular groups based on common diagnosis may improve nursing care quality. Modular nurses assigned to patients on a general medical unit made more medication errors, charted nursing interventions less frequently, and were less likely to provide prompt PRN medication administration. Of concern is the care provided to chronically ill; elderly clients not admitted to a predetermined specialty module received the poorest nursing care. We support development of specialty nursing modules to replace large, general medical units, it does not measure the impact of retention, cost, or other key variables on nurse staffing. We suggest that large medical units be divided into specialty modules and that staff rotation to general medical units be minimized.

  3. Evaluation of Radiation Dose Received by Premature Neonates Admitted to Neonatal Intensive Care Unit

    Science.gov (United States)

    Aramesh, Mohmmadreza; Zanganeh, Kobra Aria; Dehdashtian, Masoud; Malekian, Arash; Fatahiasl, Jafar

    2017-01-01

    Background This study aimed to evaluate the radiation dose received by premature neonates using diagnostic radiographies. Methods This cross-sectional study was conducted on 116 premature neonates with gestational age from 25 to 37 weeks; with the diagnosis of neonatal respiratory distress syndrome (NRDS) and tachypnea, they were admitted to a neonatal intensive care unit (NICU) at Ahvaz Imam Khomeini Hospital in 2015. For assessing the dose received, the model GR-200 thermoluminescent dosimeter (TLD) was used. For each premature neonate under radiation, three TLDs separately (one for each) were placed on surfaces of Ch1, T1, and G1 (chest, thyroid, and gonad of first newborn, respectively). Moreover, for the adjacent neonate at a distance of 60 - 100 cm, two TLDs were laid in the surfaces of T2 and G2 (thyroid and gonad of second newborn, respectively). The dose received by TLDs for any baby and the adjacent neonate under the entrance surface dose (ESD) was estimated. Results The mean of neonates’ weight under study was 1,950.78 ± 484.9 g. During the hospitalization period, minimum one and maximum three radiographies were done for any premature neonate. The doses received in the premature neonates to Ch1, T1 and G1 were 0.08 ± 0.01, 0.06 ± 0.01, and 0.05 ± 0.01 mSv, respectively and for adjacent infants for T2 and G2 were 0.003 ± 0.001 and 0.002 ± 0.0009 mSv, respectively. Conclusions In the study, radiation dose received by organs at risk of premature neonates was lower than the international criteria and standards, therefore, also due to the lack of radiation damage threshold, to limit collimator, and the use of the proper filtration, kilovoltage and time during radiography of premature neonates are recommended. PMID:28090228

  4. Evaluating Water Quality Response and Controlling Variables for Burned Watersheds in the Western United States

    Science.gov (United States)

    Rust, A.; Saxe, S.; Hogue, T. S.; McCray, J. E.

    2016-12-01

    Increasing wildfire size and frequency in the Western United States creates short-term and long-term impacts on water quality. Surface water in forested watersheds provides water for municipal water supplies and aquatic ecosystems. After fire, increased runoff and erosion lead to elevated loading of nutrients, sediment, and metals. Studies on individual fires have observed mobilization of contaminants, nutrients, metals and sediments into receiving waters. Other studies focused on individual fires over a short period, 1-3 years after fire. The objective of this study is to utilize an extensive historical water quality database, assembled by the authors, to identify trends in post-fire water quality response for the ten years following a significant fire. Specifically, we investigate the variability of post-fire water quality response and determine the key drivers impacting the immediate contaminant flux, recovery over the longer-term and ultimate resiliency of impacted watersheds and municipal water supplies. Results show that the most common post-fire response was increased nutrient loading. Thirty-two western watersheds experienced significant increases in NO3-, NO2-, NH3, and total nitrogen loading for the first five years after fire and remained elevated ten years after fire. Dissolved and total phosphorous significantly increased in 32 western watersheds for the first five years after fire. The majority of these water bodies returned to normal loading after 10 years. Dissolved ions such as calcium, magnesium, and chloride were also exported from over 32 watersheds for the first five years after fire. Using multiple linear regression analysis, we also identify the key physical watershed characteristics that drive post-fire water quality response and recovery. Burn severity, burn area and aridity index all influence the degree of water quality response. Our work provides managers with critical information to evaluate water supply impacts, including short

  5. Evaluation of Ozone Application in Dental Unit Water Lines Con¬taminated with Pathogenic Acanthamoeba

    Directory of Open Access Journals (Sweden)

    Wafaa HIKAL

    2015-10-01

    Full Text Available Background: In this study morphological and molecular characterization of Acan­thamoeba strains, isolated from dental unit waterlines (DUWLs were surveyed and the levels of disinfection achievable in vitro by the application of ozone disinfect­ant to DUWLs were evaluate.Methods: Water samples were collected from air-water syringes, cup fillers and tap water before and at the end of the working day. They were cultured on non-nutrient agar (NNA plates. Species identification was carried out with a PCR assay based on sequence analysis of the 18S rRNA gene. The cellular response to ozone was tested on Acanthamoeba cyst with different doses at different contact time in vitro twice.Results: Prevalence rates for Acanthamoeba contamination were 100, 100 and 72% for air-water syringes, cup fillers and tap water, respectively. The morphological analysis revealed the presence of A. castellanii, A. griffin, A. hatchitti and A. lenticulata. Phylogenetic analysis of the sequences showed the four strains to be closely related to a sequence type (T3, T4, T5 and T11. Acanthamoeba cells were stained with try­pan blue, which revealed killed of Acanthamoeba instantaneously after 10 minutes in ozonized water. There was no growth of Acanthamoeba occurred after ozone treat­ment in water bottles for 5 minutes with a flow rate of 500 mg/hour.Conclusion: Ozone can play an important role in controlling the problem of contami­nation of DUWLs as a potent disinfectant.

  6. [Epidemiological characteristics of patients evaluated with fibromyalgia in the Assessment of Disability Unit of Madrid].

    Science.gov (United States)

    Regal Ramos, R J

    To determine the epidemiological characteristics of patients with fibromyalgia requiring assessment of incapacity for work. A descriptive study was conducted on the patients evaluated in the Medical Unit of the National Institute of Social Security in Madrid in the period from 2005 to 2014 with the diagnosis of fibromyalgia. A study was made on the variables: age, sex, marital status, comorbidity (hypothyroidism, neck pain, psychiatric disorders, and carpal tunnel syndrome), professional occupation, level of education, and type of affiliation to the National Institute of Social Security. The total number of patients studied was 5,501. The median age was 53 years. Compared to the general working population in our area there were 47% more women, 12% less married people, 25% less workers with higher education, and 23% more unskilled occupations. As regards the working population in our area, there is a markedly increased prevalence of neck pain (prevalence ratio: 2.0), hypothyroidism (prevalence ratio 2.4), and carpal tunnel syndrome (prevalence ratio: 3.0). More than half (58%) of the sample presented with psychiatric disorders. It can be concluded that the profile of the patient with fibromyalgia assessed in the UMEVI is a woman, aged 46-60 years, mostly with a relatively unskilled job, and with primary level education. More than half of the cases had associated psychiatric disorders, and often associated with neck pain diagnoses, carpal tunnel syndrome, and hypothyroidism. Copyright © 2016 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  7. Evaluation of the predictive indices for candidemia in an adult intensive care unit

    Directory of Open Access Journals (Sweden)

    Gilberto Gambero Gaspar

    2015-02-01

    Full Text Available INTRODUCTION: To evaluate predictive indices for candidemia in an adult intensive care unit (ICU and to propose a new index. METHODS: A prospective cohort study was conducted between January 2011 and December 2012. This study was performed in an ICU in a tertiary care hospital at a public university and included 114 patients staying in the adult ICU for at least 48 hours. The association of patient variables with candidemia was analyzed. RESULTS: There were 18 (15.8% proven cases of candidemia and 96 (84.2% cases without candidemia. Univariate analysis revealed the following risk factors: parenteral nutrition, severe sepsis, surgical procedure, dialysis, pancreatitis, acute renal failure, and an APACHE II score higher than 20. For the Candida score index, the odds ratio was 8.50 (95% CI, 2.57 to 28.09; the sensitivity, specificity, positive predictive value, and negative predictive value were 0.78, 0.71, 0.33, and 0.94, respectively. With respect to the clinical predictor index, the odds ratio was 9.45 (95%CI, 2.06 to 43.39; the sensitivity, specificity, positive predictive value, and negative predictive value were 0.89, 0.54, 0.27, and 0.96, respectively. The proposed candidemia index cutoff was 8.5; the sensitivity, specificity, positive predictive value, and negative predictive value were 0.77, 0.70, 0.33, and 0.94, respectively. CONCLUSIONS: The Candida score and clinical predictor index excluded candidemia satisfactorily. The effectiveness of the candidemia index was comparable to that of the Candida score.

  8. Injectable in situ forming drug delivery system for cancer chemotherapy using a novel tissue adhesive: characterization and in vitro evaluation.

    Science.gov (United States)

    Kakinoki, Sachiro; Taguchi, Tetsushi; Saito, Hirofumi; Tanaka, Junzo; Tateishi, Tetsuya

    2007-06-01

    Injectable polymers that are biocompatible and biodegradable are important biomaterials for drug delivery system (DDS) and tissue engineering. We have already developed novel tissue adhesives consisting of biomacromolecules and organic acid derivatives with active ester groups. The resulting tissue adhesive forms in situ as a gel and has high bonding strength for living tissue as well as it has good biocompatibility and biodegradability. Here, we report on the physicochemical properties and in vitro evaluation of this novel tissue adhesive consisting of human serum albumin (HSA) and tartaric acid derivative (TAD) containing doxorubicin hydrochloride (DOX). The results of the measurement of physicochemical characteristics indicate that the gelation time and gel strength of HSA-TAD gels can be controlled according to the material composition. The bonding strength of HSA-TAD adhesives was found to be sufficient to adhere at focus and to correspond with the cross-linking density of HSA-TAD gels. Furthermore, the release of DOX from HSA-TAD gels was sustained for approximately 100 h in an in vitro evaluation. The novel tissue adhesive, therefore, is expected to be applicable for use as an injectable in situ forming DDS.

  9. History and evaluation of national-scale geochemical data sets for the United States

    Science.gov (United States)

    Smith, David B.; Smith, Steven M.; Horton, John D.

    2013-01-01

    Six national-scale, or near national-scale, geochemical data sets for soils or stream sediments exist for the United States. The earliest of these, here termed the ‘Shacklette’ data set, was generated by a U.S. Geological Survey (USGS) project conducted from 1961 to 1975. This project used soil collected from a depth of about 20 cm as the sampling medium at 1323 sites throughout the conterminous U.S. The National Uranium Resource Evaluation Hydrogeochemical and Stream Sediment Reconnaissance (NURE-HSSR) Program of the U.S. Department of Energy was conducted from 1975 to 1984 and collected either stream sediments, lake sediments, or soils at more than 378,000 sites in both the conterminous U.S. and Alaska. The sampled area represented about 65% of the nation. The Natural Resources Conservation Service (NRCS), from 1978 to 1982, collected samples from multiple soil horizons at sites within the major crop-growing regions of the conterminous U.S. This data set contains analyses of more than 3000 samples. The National Geochemical Survey, a USGS project conducted from 1997 to 2009, used a subset of the NURE-HSSR archival samples as its starting point and then collected primarily stream sediments, with occasional soils, in the parts of the U.S. not covered by the NURE-HSSR Program. This data set contains chemical analyses for more than 70,000 samples. The USGS, in collaboration with the Mexican Geological Survey and the Geological Survey of Canada, initiated soil sampling for the North American Soil Geochemical Landscapes Project in 2007. Sampling of three horizons or depths at more than 4800 sites in the U.S. was completed in 2010, and chemical analyses are currently ongoing. The NRCS initiated a project in the 1990s to analyze the various soil horizons from selected pedons throughout the U.S. This data set currently contains data from more than 1400 sites. This paper (1) discusses each data set in terms of its purpose, sample collection protocols, and analytical

  10. History and evaluation of national-scale geochemical data sets for the United States

    Directory of Open Access Journals (Sweden)

    David B. Smith

    2013-03-01

    Full Text Available Six national-scale, or near national-scale, geochemical data sets for soils or stream sediments exist for the United States. The earliest of these, here termed the ‘Shacklette’ data set, was generated by a U.S. Geological Survey (USGS project conducted from 1961 to 1975. This project used soil collected from a depth of about 20 cm as the sampling medium at 1323 sites throughout the conterminous U.S. The National Uranium Resource Evaluation Hydrogeochemical and Stream Sediment Reconnaissance (NURE-HSSR Program of the U.S. Department of Energy was conducted from 1975 to 1984 and collected either stream sediments, lake sediments, or soils at more than 378,000 sites in both the conterminous U.S. and Alaska. The sampled area represented about 65% of the nation. The Natural Resources Conservation Service (NRCS, from 1978 to 1982, collected samples from multiple soil horizons at sites within the major crop-growing regions of the conterminous U.S. This data set contains analyses of more than 3000 samples. The National Geochemical Survey, a USGS project conducted from 1997 to 2009, used a subset of the NURE-HSSR archival samples as its starting point and then collected primarily stream sediments, with occasional soils, in the parts of the U.S. not covered by the NURE-HSSR Program. This data set contains chemical analyses for more than 70,000 samples. The USGS, in collaboration with the Mexican Geological Survey and the Geological Survey of Canada, initiated soil sampling for the North American Soil Geochemical Landscapes Project in 2007. Sampling of three horizons or depths at more than 4800 sites in the U.S. was completed in 2010, and chemical analyses are currently ongoing. The NRCS initiated a project in the 1990s to analyze the various soil horizons from selected pedons throughout the U.S. This data set currently contains data from more than 1400 sites. This paper (1 discusses each data set in terms of its purpose, sample collection protocols

  11. Recent advances on glass-forming systems driven far from equilibrium. Special issue marking the completion of the Research Unit FOR 1394 `Nonlinear response to probe vitrification'

    Science.gov (United States)

    Fuchs, Matthias

    2017-08-01

    The nature of the glass transition is one of the frontier questions in Statistical Physics and Materials Science. Highly cooperative structural processes develop in glass-forming melts exhibiting relaxational dynamics which is spread out over many decades in time. While considerable progress has been made in recent decades towards understanding dynamical slowing-down in quiescent systems, the interplay of glassy dynamics with external fields reveals a wealth of novel phenomena yet to be explored. This special issue focuses on recent results obtained by the Research Unit FOR 1394 `Nonlinear response to probe vitrification' which was funded by the German Science Foundation (DFG). In the projects of the research unit, strong external fields were used in order to gain insights into the complex structural and transport phenomena at the glass transition under far-from-equilibrium conditions. This aimed inter alia to test theories of the glass transition developed for quiescent systems by pushing them beyond their original regime. Combining experimental, simulational, and theoretical efforts, the eight projects within the FOR 1394 measured and determined aspects of the nonlinear response of supercooled metallic, polymeric, and silica melts, of colloidal dispersions, and of ionic liquids. Applied fields included electric and mechanic fields, and forced active probing (`micro-rheology'), where a single probe is forced through the glass-forming host. Nonlinear stress-strain and force-velocity relations as well as nonlinear dielectric susceptibilities and conductivities were observed. While the physical manipulation of melts and glasses is interesting in its own right, especially technologically, the investigations performed by the FOR 1394 suggest to use the response to strong homogeneous and inhomogeneous fields as technique to explore on the microscopic level the cooperative mechanisms in dense melts of strongly interacting constituents. Questions considered concern the

  12. FY16 Annual Accomplishments - Waste Form Development and Performance: Evaluation Of Ceramic Waste Forms - Comparison Of Hot Isostatic Pressed And Melt Processed Fabrication Methods

    Energy Technology Data Exchange (ETDEWEB)

    Amoroso, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Dandeneau, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-10-13

    FY16 efforts were focused on direct comparison of multi-phase ceramic waste forms produced via melt processing and HIP methods. Based on promising waste form compositions previously devised at SRNL, simulant material was prepared at SRNL and a portion was sent to the Australian Nuclear Science and Technology Organization (ANSTO) for HIP treatments, while the remainder of the material was melt processed at SRNL. The microstructure, phase formation, elemental speciation, and leach behavior, and radiation stability of the fabricated ceramics was performed. In addition, melt-processed ceramics designed with different fractions of hollandite, zirconolite, perovskite, and pyrochlore phases were investigated. for performance and properties.

  13. Evaluation of ultramafic deposits in the Eastern United States and Puerto Rico as sources of magnesium for carbon dioxide sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Fraser Goff; George Guthrie; Bruce Lipin; Melissa Fite; Steve Chipera; Dale Counce; Emily Kluk; Hans Ziock

    2000-04-01

    In this report, the authors evaluate the resource potential of extractable magnesium from ultramafic bodies located in Vermont, the Pennsylvania-Maryland-District-of-Columbia (PA-MD-DC) region, western North Carolina, and southwestern Puerto Rico. The first three regions occur in the Appalachian Mountains and contain the most attractive deposits in the eastern United States. They were formed during prograde metamorphism of serpentinized peridotite fragments originating from an ophiolite protolith. The ultramafic rocks consist of variably serpentinized dunite, harzburgite, and minor iherzolite generally containing antigorite and/or lizardite as the major serpentine minor phases. Chrysotile contents vary from minor to major, depending on occurrence. Most bodies contain an outer sheath of chlorite-talc-tremolite rock. Larger deposits in Vermont and most deposits in North Carolina contain a core of dunite. Magnesite and other carbonates are common accessories. In these deposits, MgO ranges from 36 to 48 wt % with relatively pure dunite having the highest MgO and lowest H{sub 2}O contents. Ultramafic deposits in southwestern Puerto Rico consist of serpentinized dunite and harzburgite thought to be emplaced as large diapirs or as fragments in tectonic melanges. They consist of nearly pure, low-grade serpentinite in which lizardite and chrysotile are the primary serpentine minerals. Chlorite is ubiquitous in trace amounts. Magnesite is a common accessory. Contents of MgO and H{sub 2}O are rather uniform at roughly 36 and 13 wt %. Dissolution experiments show that all serpentinites and dunite-rich rocks are soluble in 1:1 mixtures of 35% HCl and water by volume. The experiments suggest that low-grade serpentinites from Puerto Rico are slightly more reactive than the higher grade, antigorite-bearing serpentinites of the Appalachian Mountains. The experiments also show that the low-grade serpentinites and relatively pure dunites contain the least amounts of undesirable

  14. Evaluation on radioactive waste disposal amount of Kori Unit 1 reactor vessel considering cutting and packaging methods

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yu Jong; Lee, Seong Cheol; Kim, Chang Lak [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2016-06-15

    Decommissioning of nuclear power plants has become a big issue in South Korea as some of the nuclear power plants in operation including Kori unit 1 and Wolsung unit 1 are getting old. Recently, Wolsung unit 1 received permission to continue operation while Kori unit 1 will shut down permanently in June 2017. With the consideration of segmentation method and disposal containers, this paper evaluated final disposal amount of radioactive waste generated from decommissioning of the reactor pressure vessel in Kori unit 1 which will be decommissioned as the first in South Korea. The evaluation results indicated that the final disposal amount from the top and bottom heads of the reactor pressure vessel with hemisphere shape decreased as they were cut in smaller more effectively than the cylindrical part of the reactor pressure vessel. It was also investigated that 200 L and 320 L radioactive waste disposal containers used in Kyung-Ju disposal facility had low payload efficiency because of loading weight limitation.

  15. Teaching Form as Form

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2012-01-01

    understanding of form per se, or, to use an expression from this text, of form as form. This challenge can be reduced to one question: how can design teaching support students in achieving not only the ability to recognize and describe different form-related concepts in existing design (i.e. analytical...... means that form serves both as the connective value and as the concept for reflection. In other words, form is observed as form, not anything else. The didactical challenge of teaching form as form is accentuated by students’ everyday-based pre-orientation towards function at the expense of form....... In general, students enter design education as far more skilled observers with regards to function than form. They are, in other words, predisposed to observe objects asking ‘what is?’, rather than ‘how is?’. This habit has not only cognitive implications. It is closely intertwined with a rudimentary...

  16. Teaching Form as Form

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    2012-01-01

    understanding of form per se, or, to use an expression from this text, of form as form. This challenge can be reduced to one question: how can design teaching support students in achieving not only the ability to recognize and describe different form-related concepts in existing design (i.e. analytical...... means that form serves both as the connective value and as the concept for reflection. In other words, form is observed as form, not anything else. The didactical challenge of teaching form as form is accentuated by students’ everyday-based pre-orientation towards function at the expense of form...... vocabulary of form. Even in cases in which teaching uses terms and phrases from everyday life (for instance, ‘intersection’), the meaning of the word cannot necessarily be transmitted directly from an ordinary vocabulary into a design context. And it is clearly a common issue for the contributions...

  17. Completion Report for Model Evaluation Well ER-5-5: Corrective Action Unit 98: Frenchman Flat

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Underground Test Area and Boreholes Programs and Operations

    2013-01-18

    Model Evaluation Well ER-5-5 was drilled for the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office in support of Nevada Environmental Management Operations at the Nevada National Security Site (formerly known as the Nevada Test Site). The well was drilled in July and August 2012 as part of a model evaluation well program in the Frenchman Flat area of Nye County, Nevada. The primary purpose of the well was to provide detailed geologic, hydrogeologic, chemical, and radiological data that can be used to test and build confidence in the applicability of the Frenchman Flat Corrective Action Unit flow and transport models for their intended purpose. In particular, this well was designed to obtain data to evaluate the uncertainty in model forecasts of contaminant migration from the upgradient underground nuclear test MILK SHAKE, conducted in Emplacement Hole U-5k in 1968, which were considered to be uncertain due to the unknown extent of a basalt lava-flow aquifer present in this area. Well ER-5-5 is expected to provide information to refine the Phase II Frenchman Flat hydrostratigraphic framework model, if necessary, as well as to support future groundwater flow and transport modeling. The 31.1-centimeter (cm) diameter hole was drilled to a total depth of 331.3 meters (m). The completion string, set at the depth of 317.2 m, consists of 16.8-cm stainless-steel casing hanging from 19.4-cm carbon-steel casing. The 16.8-cm stainless-steel casing has one slotted interval open to the basalt lava-flow aquifer and limited intervals of the overlying and underlying alluvial aquifer. A piezometer string was also installed in the annulus between the completion string and the borehole wall. The piezometer is composed of 7.3-cm stainless-steel tubing suspended from 6.0-cm carbon-steel tubing. The piezometer string was landed at 319.2 m, to monitor the basalt lava-flow aquifer. Data collected during and shortly after hole construction include

  18. Using imagery perspective to access two distinct forms of self-knowledge: associative evaluations versus propositional self-beliefs.

    Science.gov (United States)

    Libby, Lisa K; Valenti, Greta; Hines, Karen A; Eibach, Richard P

    2014-04-01

    When mentally simulating life events, people may visualize them from either an actor's 1st-person or observer's 3rd-person visual perspective. Two experiments demonstrated that visual perspective differentially determines reliance on 2 distinct forms of self-knowledge: associative evaluations of the simulated environment and propositional self-beliefs about relevant values and preferences. Implicit measures indexed associative evaluations of environmental stimuli (political candidates, outgroups); explicit measures indexed propositional self-beliefs about relevant personal values or preferences. A separate session manipulated participants' visual perspective for mentally simulating a pertinent event (voting, interracial interaction) as they forecasted their behavior or feelings if that event occurred. Forecasts corresponded more closely with associative evaluations from the 1st-person than 3rd-person perspective but more closely with propositional self-beliefs from the 3rd-person than 1st-person. Results have practical implications for channeling the power of mental simulation to desired ends and theoretical implications for understanding the pathways by which imagery and mental simulation shape cognition.

  19. Numerical simulation on the adaptation of forms in trabecular bone to mechanical disuse and basic multi-cellular unit activation threshold at menopause

    Institute of Scientific and Technical Information of China (English)

    He Gong; Yubo Fan; Ming Zhang

    2008-01-01

    The objective of this paper is to identify the effects of mechanical disuse and basic multi-cellular unit (BMU) activation threshold on the form of trabecular bone during menopause. A bone adaptation model with mechanical-biological factors at BMU level was integrated with finite element analysis to simulate the changes of trabecular bone structure during menopause. Mechanical disuse and changes in the BMU activation threshold were applied to the model for the period from 4 years before to 4 years after menopause.The changes in bone volume fraction, trabecular thickness and fractal dimension of the trabecular structures were used to quantify the changes of trabecular bone in three different cases associated with mechanical disuse and BMU activation threshold. It was found that the changes in the simulated bone volume fraction were highly correlated and consistent with clinical data, and that the trabecular thickness reduced signi-ficantly during menopause and was highly linearly correlated with the bone volume fraction, and that the change trend of fractal dimension of the simulated trabecular structure was in correspondence with clinical observations. The numerical simulation in this paper may help to better understand the relationship between the bone morphology and the mecha- nical, as well as biological environment; and can provide a quantitative computational model and methodology for the numerical simulation of the bone structural morphological changes caused by the mechanical environment, and/or the biological environment.

  20. [The effects of an aroma candy on oral Candida albicans colony-forming units (CFU) and oral hygiene states in healthy elderly carrying Candida albicans].

    Science.gov (United States)

    Suzuki, Motofumi; Hayama, Kazumi; Takahashi, Miki; Ezawa, Kunio; Yamazaki, Masatoshi; Matsukawa, Taiji; Kishi, Akinobu; Satou, Nobuya; Abe, Shigeru

    2015-01-01

    In a preceding paper, we showed that aroma candy containing oligonol, capric acid, and cinnamon (cassia) powder had potent inhibitory activity against mycelial growth of Candida albicans in vitro and protective activity against murine oral candidiasis. In order to assess the effects of this candy (the test candy) on oral C. albicans colony-forming units (CFU) and oral hygiene states, a placebo-controlled double-blind crossover comparative study was performed. Twenty subjects were divided into two groups. One group ingested the test candy in the first 7 days followed by 2 weeks washing-off period, then ingested the placebo candy (control candy) for 7 days. The other group was vice versa. C. albicans CFU in all oral rinse samples from the subjects before and after 7 days ingestion of candy was measured. The degree of oral malodor in all subjects was monitored using a portable measuring instrument. The results showed no statistically significant difference between test-candy group and placebo group for C. albicans CFU. However, C. albicans CFU in test-candy group with>4,000 CFUs was significantly decreased after 7 days ingestion of test-candy (poral malodor in the test-candy group was significantly decreased after 7 days ingestion of test-candy (poral hygiene states indicated that in the test-candy group, oral malodor, glutinous feeling, and refreshing feeling significantly improved in comparison with control-candy group (poral health care of elderly carrying C. albicans.

  1. Numerical simulation on the adaptation of forms in trabecular bone to mechanical disuse and basic multi-cellular unit activation threshold at menopause

    Science.gov (United States)

    Gong, He; Fan, Yubo; Zhang, Ming

    2008-04-01

    The objective of this paper is to identify the effects of mechanical disuse and basic multi-cellular unit (BMU) activation threshold on the form of trabecular bone during menopause. A bone adaptation model with mechanical- biological factors at BMU level was integrated with finite element analysis to simulate the changes of trabecular bone structure during menopause. Mechanical disuse and changes in the BMU activation threshold were applied to the model for the period from 4 years before to 4 years after menopause. The changes in bone volume fraction, trabecular thickness and fractal dimension of the trabecular structures were used to quantify the changes of trabecular bone in three different cases associated with mechanical disuse and BMU activation threshold. It was found that the changes in the simulated bone volume fraction were highly correlated and consistent with clinical data, and that the trabecular thickness reduced significantly during menopause and was highly linearly correlated with the bone volume fraction, and that the change trend of fractal dimension of the simulated trabecular structure was in correspondence with clinical observations. The numerical simulation in this paper may help to better understand the relationship between the bone morphology and the mechanical, as well as biological environment; and can provide a quantitative computational model and methodology for the numerical simulation of the bone structural morphological changes caused by the mechanical environment, and/or the biological environment.

  2. CKbeta8-1 alters expression of cyclin E in colony forming units-granulocyte macrophage (CFU-GM) lineage from human cord blood CD34+ cells.

    Science.gov (United States)

    Noh, Eui Kyu; Ra, Jae Sun; Lee, Seong Ae; Kwon, Byoung S; Han, In Seob

    2005-12-31

    A C6 beta-chemokine, CKbeta8-1, suppressed the colony formation of CD34+ cells of human cord blood (CB). Molecular mechanisms involved in CKbeta8-1-medicated suppression of colony formation of CD34+ cells are not known. To address this issue, the level of various G1/S cell cycle regulating proteins in CKbeta8-1-treated CD34+ cells were compared with those in untreated CD34+ cells. CKbeta8-1 did not significantly alter the expression of the G1/S cycle regulation proteins (cyclin D1, D3, and E), CDK inhibitor (p27and Rb), and other cell proliferation regulation protein (p53) in CB CD34+ cells. Here we describe an in vitro system in which CB CD34+ cells were committed to a multipotent progenitor lineage of colony forming units-granulocyte/macrophage (CFU-GM) by a simple combination of recombinant human (rh) GM-CSF and rhIL-3. In this culture system, we found that cyclin E protein appeared later and disappeared faster in the CKbeta8-1-treated cells than in the control cells during CFU-GM lineage development. These findings suggested that cyclin E may play a role in suppressing the colony formation of CFU-GM by CKbeta8-1.

  3. Percutaneous dilatational tracheostomy without fiber optic bronchoscopy-Evaluation of 80 intensive care units cases

    NARCIS (Netherlands)

    J.A. Calvache (Jose Andrés); R.A. Molina García (Rodrigo); A.L. Trochez (Adolfo); J. Benitez (Javier); L.A. Flga (Lucía Arroyo)

    2013-01-01

    textabstractBackground: The development of percutaneous dilatational tracheostomy techniques (PDT) has facilitated the procedure in Intensive Care Units (ICU). Objective: To describe the early intra and post-operative complications in ICU patients requiring percutaneous dilatational tracheostomy usi

  4. Percutaneous dilatational tracheostomy without fiber optic bronchoscopy-Evaluation of 80 intensive care units cases

    NARCIS (Netherlands)

    J.A. Calvache (Jose Andrés); R.A. Molina García (Rodrigo); A.L. Trochez (Adolfo); J. Benitez (Javier); L.A. Flga (Lucía Arroyo)

    2013-01-01

    textabstractBackground: The development of percutaneous dilatational tracheostomy techniques (PDT) has facilitated the procedure in Intensive Care Units (ICU). Objective: To describe the early intra and post-operative complications in ICU patients requiring percutaneous dilatational tracheostomy usi

  5. Unit Manning System: Human Dimensions Field Evaluation of the COHORT company Replacement Model

    Science.gov (United States)

    1994-04-18

    tha: their superiors make such an attempt. Whether we speak of "unit cohesion" (Henderson, 1985; Johns, 1984), "unit morale" (Gal, 1986), "combat...differences. Generally speaking , mean differences on the five point scales must now be in the .4 to .5 range instead of the .2 to .3 range in order to...Marlowe, et al., 1985). Training in basic skiils , along with the maintenance of barracks standards and physical readiness, were all areas where COHORT

  6. FY16 Annual Accomplishments - Waste Form Development and Performance: Evaluation Of Ceramic Waste Forms - Comparison Of Hot Isostatic Pressed And Melt Processed Fabrication Methods

    Energy Technology Data Exchange (ETDEWEB)

    Amoroso, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Dandeneau, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-10-13

    FY16 efforts were focused on direct comparison of multi-phase ceramic waste forms produced via melt processing and HIP methods. Based on promising waste form compositions previously devised at SRNL[13], simulant material was prepared at SRNL and a portion was sent to the Australian Nuclear Science and Technology Organization (ANSTO) for HIP treatments, while the remainder of the material was melt processed at SRNL. The microstructure, phase formation, elemental speciation, and leach behavior, and radiation stability of the fabricated ceramics was performed. In addition, melt-processed ceramics designed with different fractions of hollandite, zirconolite, perovskite, and pyrochlore phases were investigated. for performance and properties. Table 1 lists the samples studied.

  7. Evaluation of the predictors for duration of mechanical ventilation in respiratory intensive care unit

    Directory of Open Access Journals (Sweden)

    Hira H

    2006-01-01

    Full Text Available Background: Mechanical ventilation (MV is a life saving modality. Till no method is evolved to predict the duration of this treatment. This study is undertaken to evaluate the clinical and laboratory parameters at initiation and 48 hour of the patient being treated by mechanical ventilation; and correlate these parameters with the duration of MV required. Methods: It was prospective observational study conducted in the respiratory intensive care unit (RICU of a tertiary referral and teaching hospital. Thirty consecutive patients suffering from various medical diseases requiring MV were the participants. Clinical, laboratory, ventilatory parameters and six severity scores viz.; GCS, APACHE-II, SAPS, OSF, ALI/ARDS and Sepsis/Septic shock criteria of each patient, both at initiation and at 48 hour of MV were recorded. Correlation between various severity scores at initiation and at 48 hour of initiation with duration of mechanical ventilation was computed. Results: Based on the duration of mechanical ventilation required, the patients were divided in two groups. Those requiring mechanical ventilation < 7 days and> 7 days were designated Group I and Group II respectively. Three out of 6 severity scores (GCS, APACHE-II, SAPS recorded at 48 hour of MV showed statistically significant difference between the both groups with p value of 0.010, 0.009 and 0.006 respectively. Further stepwise logistic regression analysis showed that SAPS score at 48 hour of initiation was the best predictor of duration of MV. It was found that a cut off value of 15 for SAPS score at 48 hour might predict the duration of MV i.e. < 7days or> 7 days. Based on linear regression analysis a simple equation was formulated by putting the SAPS value at 48 hour, the value of Y was computed. If MV required was less than 7 days, the value of Y was more than - 0.172 and if need of mechanical ventilation was more than 7 days, Y was less than -0.1720. Conclusions: For patients requiring

  8. Evaluation quantitative des produits formés lors de l'évolution géochimique de la matière organique Quantitative Evaluation of Products Formed During the Geochemical Evolution of Organic Matter

    Directory of Open Access Journals (Sweden)

    Pelet R.

    2006-11-01

    Full Text Available L'évaluation quantitative des produits mobiles formés lors de l'évolution géochimique de la matière organique est nécessaire parce qu'on ne peut jamais retrouver ces produits en place dans. la roche où ils ont pris naissance. Ils ont, en effet, pu migrer durant l'histoire géologique, et de toute manière une fraction, importante et non connue, se perd lors de la prise des échantillons puis de leur conservation avant analyse. La connaissance de l'analyse d'un état E et d'un état plus évolué E' ne suffit pas pour reconstituer les quantités de produits formés. La pyrolyse type Rock-Eval sur kérogènes, avec détermination du carbone résiduel, permet par contre, à partir d'une hypothèse raisonnable, de calculer les hydrocarbures produits. L'analyse élémentaire permet d'y ajouter CO2, H2O, H2S et N2 (considérés comme seuls produits à côté des hydrocarbures. Une analyse chromatographique sommaire supplémentaire permet d'estimer la composition globale des hydrocarbures. Dans le cas des roches, on propose des techniques de correction de l'effet de matrice pratiquement utilisables et qui permettent de retrouver les résultats précédents, au prix d'une incertitude accrue. The mobile products formed during the geochemical evolution of organic matter must be quantitatively evaluated because these products can never be found in place in the rock where they were formed. Indeed, they may have migrated during geological history, and in any case a large and unknown fraction gets lost when samples are taken and then stored before being analysed. Knowing the elemental analysis of a state E and of a more evolved state E' does not suffice for recreating the amounts of products formed. On the other hand Rock-Eval type pyrolysis of kerogens, including the determination of the residual carbon, can be used to compute the hydrocarbons produced, on the basis of a reasonable hypothesis. Elemental analysis then enables the evaluation of CO2, H2O

  9. Glass-Forming Ability of an Iron-Based Alloy Enhanced by Co Addition and Evaluated by a New Criterion

    Institute of Scientific and Technical Information of China (English)

    CHEN Qing-Jun; SHEN Jun; FAN Hong-Bo; SUN Jian-Fei; HUANG Yong-Jiang; MCCARTNEY D. G.

    2005-01-01

    @@ A new Fe-based alloy that can be cast into a fully amorphous rod with a diameter of at least 16mm by the conventional copper-mould casting technique is obtained by partially replacing Fe with Co in a previously reported Fe-based bulk metallic glass. The preliminary thermodynamic analysis indicates that the Co-containing alloy has a significantly lower Gibbs free energy difference between the undercooled melt and the corresponding crystalline solid, compared to the Co-free alloy, reflecting the dramatic role of the Co addition in stabilizing the supercooled melt and facilitating glass formation in iron-based alloys. Here, a new criterion, derived from the classical nucleation and growth theory, is introduced to evaluate the glass-forming ability of Fe-based bulk metallic glasses.

  10. [Evaluation of the tree form quality of middle-aged Pinus tabuliformis plantation under different canopy densities in Huanglong Mountains, Northwest China].

    Science.gov (United States)

    You, Jian-jian; Zhang, Wen-hui; Deng, Lei

    2015-07-01

    To clarify the effects of different canopy densities on tree form quality of Pinus tabuliformis, a hierarchical indicator system was structured, which brought about a set of grading criteria to evaluate tree form quality of the middle-aged P. tabuliformis plantation under four canopy densities in Huanglong Mountains by using the analytic hierarchy process (AHP). Plots were divided into four classes according to the stand canopy density (CD) : CDdiameter at breast height (DBH), tree height, diameter height ratio, taperingness, stem straightness, forking ratio, height under living branch, number of branches, max-branch base diameter and average base diameter of branches, the tree form quality could be evaluated. Among these factors, stem straightness, forking ratio and DBH were the most important ones influencing the tree form quality with a total weight of 0.7382. So, these three indicators were the major determinants of tree form quality. The comprehensive scores of the tree form quality evaluations fluctuated as the canopy density decreased and topped at 90.28 when CD was valued at 0.75 (type 2). The indicators and evaluation system developed in this study were easy to operate, and quite fit for solving the quantity problem of the tree form quality evaluation. Our system would be capable for applications in evaluating the tree form quality of other tree species on the Loess Plateau.

  11. Cardiac arrhythmias in stroke unit patients. Evaluation of the cardiac monitoring data.

    Science.gov (United States)

    Fernández-Menéndez, S; García-Santiago, R; Vega-Primo, A; González Nafría, N; Lara-Lezama, L B; Redondo-Robles, L; Montes-Montes, M; Riveira-Rodríguez, M C; Tejada-García, J

    2016-06-01

    Cardiac arrhythmias are frequent in acute stroke. Stroke units are widely equipped with cardiac monitoring systems. Pre-existing heart diseases and heart-brain interactions may be implicated in causing cardiac arrhythmias in acute stroke. This article analyses cardiac arrhythmias detected in patients hospitalised in a stroke unit. Prospective observational study of consecutive patients admitted to a stroke unit with cardiac monitoring. We collected clinical data from patients and the characteristics of their cardiac arrhythmias over a 1-year period (2013). Time of arrhythmia onset, associated predisposing factors, and the therapeutic decisions made after detection of arrhythmia were examined. All patients underwent continuous cardiac monitoring during no less than 48hours. Of a total of 332 patients admitted, significant cardiac arrhythmias occurred in 98 patients (29.5%) during their stay in the stroke unit. Tachyarrhythmia (ventricular tachyarrhythmias, supraventricular tachyarrhythmias, complex ventricular ectopy) was present in 90 patients (27.1%); bradyarrhythmia was present in 13 patients (3.91%). Arrhythmias were independently associated with larger size of brain lesion and older age. In 10% of the patient total, therapeutic actions were taken after detection of significant cardiac arrhythmias. Most events occurred within the first 48hours after stroke unit admission. Systematic cardiac monitoring in patients with acute stroke is useful for detecting clinically relevant cardiac arrhythmias. Incidence of arrhythmia is higher in the first 48hours after stroke unit admission. Age and lesion size were predicted appearance of arrhythmias. Detection of cardiac arrhythmias in a stroke unit has important implications for treatment. Copyright © 2014 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.

  12. Structural characterization of the isoenzymatic forms of human myeloperoxidase: evaluation of the iron-containing prosthetic group.

    Science.gov (United States)

    Wright, J; Bastian, N; Davis, T A; Zuo, C; Yoshimoto, S; Orme-Johnson, W H; Tauber, A I

    1990-01-01

    Myeloperoxidase (MPO) from human neutrophils has been purified and found to exist in three isoenzymatic forms, resolved by ion exchange chromatography. In addition to differences in subunit size and cellular compartmentalization of the isoenzymes, differences have been reported in their activity and susceptibility to inhibition. The structural basis of these isoenzymes is unclear; we attempted to further define their functional characteristics and structural identity. First, we measured respective enzymatic activity using a panel of substrates; MPO I was found to have lower activity with some substrates (pyrogallol, guaiacol, potassium iodide [KI]), but similar activity to the other isoenzymes with 4-aminoantipyrine. These studies confirm that MPO I is enzymatically distinct from MPO II and MPO III. Next, we examined the structural basis of these differences by evaluating the iron-containing prosthetic group in each form using electron paramagnetic resonance (EPR) and determination of the pyridine hemochrome. No significant difference between the isoenzymes was noted in these parameters, suggesting that the prosthetic group is the same in each protein. The cause for any difference in enzymatic activity must lie then in variations extrinsic to the heme, and based on previous studies of the gene and protein analysis, the posttranslational modification of MPO must account for these isoenzymatic species.

  13. An Accelerated Release Study to Evaluate Long-Acting Contraceptive Levonorgestrel-Containing in Situ Forming Depot Systems.

    Science.gov (United States)

    Janagam, Dileep R; Wang, Lizhu; Ananthula, Suryatheja; Johnson, James R; Lowe, Tao L

    2016-09-01

    Biodegradable polymer-based injectable in situ forming depot (ISD) systems that solidify in the body to form a solid or semisolid reservoir are becoming increasingly attractive as an injectable dosage form for sustained (months to years) parenteral drug delivery. Evaluation of long-term drug release from the ISD systems during the formulation development is laborious and costly. An accelerated release method that can effectively correlate the months to years of long-term release in a short time such as days or weeks is economically needed. However, no such accelerated ISD system release method has been reported in the literature to date. The objective of the current study was to develop a short-term accelerated in vitro release method for contraceptive levonorgestrel (LNG)-containing ISD systems to screen formulations for more than 3-month contraception after a single subcutaneous injection. The LNG-containing ISD formulations were prepared by using biodegradable poly(lactide-co-glycolide) and polylactic acid polymer and solvent mixtures containing N-methyl-2-pyrrolidone and benzyl benzoate or triethyl citrate. Drug release studies were performed under real-time (long-term) conditions (PBS, pH 7.4, 37 °C) and four accelerated (short-term) conditions: (A) PBS, pH 7.4, 50 °C; (B) 25% ethanol in PBS, pH 7.4, 50 °C; (C) 25% ethanol in PBS, 2% Tween 20, pH 7.4, 50 °C; and (D) 25% ethanol in PBS, 2% Tween 20, pH 9, 50 °C. The LNG release profile, including the release mechanism under the accelerated condition D within two weeks, correlated (r² ≥ 0.98) well with that under real-time conditions at four months.

  14. An Accelerated Release Study to Evaluate Long-Acting Contraceptive Levonorgestrel-Containing in Situ Forming Depot Systems

    Directory of Open Access Journals (Sweden)

    Dileep R. Janagam

    2016-09-01

    Full Text Available Biodegradable polymer-based injectable in situ forming depot (ISD systems that solidify in the body to form a solid or semisolid reservoir are becoming increasingly attractive as an injectable dosage form for sustained (months to years parenteral drug delivery. Evaluation of long-term drug release from the ISD systems during the formulation development is laborious and costly. An accelerated release method that can effectively correlate the months to years of long-term release in a short time such as days or weeks is economically needed. However, no such accelerated ISD system release method has been reported in the literature to date. The objective of the current study was to develop a short-term accelerated in vitro release method for contraceptive levonorgestrel (LNG-containing ISD systems to screen formulations for more than 3-month contraception after a single subcutaneous injection. The LNG-containing ISD formulations were prepared by using biodegradable poly(lactide-co-glycolide and polylactic acid polymer and solvent mixtures containing N-methyl-2-pyrrolidone and benzyl benzoate or triethyl citrate. Drug release studies were performed under real-time (long-term conditions (PBS, pH 7.4, 37 °C and four accelerated (short-term conditions: (A PBS, pH 7.4, 50 °C; (B 25% ethanol in PBS, pH 7.4, 50 °C; (C 25% ethanol in PBS, 2% Tween 20, pH 7.4, 50 °C; and (D 25% ethanol in PBS, 2% Tween 20, pH 9, 50 °C. The LNG release profile, including the release mechanism under the accelerated condition D within two weeks, correlated (r2 ≥ 0.98 well with that under real-time conditions at four months.

  15. An Accelerated Release Study to Evaluate Long-Acting Contraceptive Levonorgestrel-Containing in Situ Forming Depot Systems

    Science.gov (United States)

    Janagam, Dileep R.; Wang, Lizhu; Ananthula, Suryatheja; Johnson, James R.; Lowe, Tao L.

    2016-01-01

    Biodegradable polymer-based injectable in situ forming depot (ISD) systems that solidify in the body to form a solid or semisolid reservoir are becoming increasingly attractive as an injectable dosage form for sustained (months to years) parenteral drug delivery. Evaluation of long-term drug release from the ISD systems during the formulation development is laborious and costly. An accelerated release method that can effectively correlate the months to years of long-term release in a short time such as days or weeks is economically needed. However, no such accelerated ISD system release method has been reported in the literature to date. The objective of the current study was to develop a short-term accelerated in vitro release method for contraceptive levonorgestrel (LNG)-containing ISD systems to screen formulations for more than 3-month contraception after a single subcutaneous injection. The LNG-containing ISD formulations were prepared by using biodegradable poly(lactide-co-glycolide) and polylactic acid polymer and solvent mixtures containing N-methyl-2-pyrrolidone and benzyl benzoate or triethyl citrate. Drug release studies were performed under real-time (long-term) conditions (PBS, pH 7.4, 37 °C) and four accelerated (short-term) conditions: (A) PBS, pH 7.4, 50 °C; (B) 25% ethanol in PBS, pH 7.4, 50 °C; (C) 25% ethanol in PBS, 2% Tween 20, pH 7.4, 50 °C; and (D) 25% ethanol in PBS, 2% Tween 20, pH 9, 50 °C. The LNG release profile, including the release mechanism under the accelerated condition D within two weeks, correlated (r2 ≥ 0.98) well with that under real-time conditions at four months. PMID:27598191

  16. Do different standard plate counting (IDF/ISSO or AOAC) methods interfere in the conversion of individual bacteria counts to colony forming units in raw milk?

    Science.gov (United States)

    Cassoli, L D; Lima, W J F; Esguerra, J C; Da Silva, J; Machado, P F; Mourão, G B

    2016-10-01

    This study aimed to establish the correlation between individual bacterial count (IBC) obtained by flow cytometry and the number of colony forming units (CFU) determined by standard plate count (SPC) in raw milk using two different reference methodologies: the methodology of the International Dairy Federation (IDF) - International Organization for Standardization (ISO) 4833, incubation for 72 h at 30°C and the methodology of the Association of Official Analytical Chemists (AOAC), incubation for 48 h at 35°C. For this, 100 bovine milk samples (80 ml) from different farms were collected in a sterile bottle and maintained refrigerated at 4°C and were delivered to the laboratory. In the laboratory, the samples were divided into two vials of 40 ml each. Then, half of the vials were forwarded for the SPC analysis, and the other half were analysed using the equipment BactoScan FC. The analyses by flow cytometry and SPC were performed at the same time (maximum deviation of +/- 1 h). To transform the data from IBC ml(-1) to CFU ml(-1) (IDF or AOAC methodology), a standard linear regression equation was used, as recommended by IDF/ISO-196. The difference between the reference methodologies affects the equation that transforms IBC into CFU and therefore the accuracy of the results. The results estimated by the equation using the ISO 4833 methodology were on average 0·18 log units higher than the results estimated using the equation using the AOAC methodology. After the comparison of the methodologies, it was concluded that there is an impact of the reference methodologies on the conversion of the results from IBC to CFU. Depending on the methodology adopted by each laboratory or country, there may not be equivalence in the results. Hence, the laboratories specialized in milk quality analysis that have changed their methodology for analysis, passing from the MAPA (AOAC) methodology to the IDF standard, need to develop new conversion equations to make their

  17. Evaluation of autonomous recording units for detecting 3 species of secretive marsh birds

    Science.gov (United States)

    Sidie-Slettehahl, Anna M.; Jensen, Kent C.; Johnson, Rex R.; Arnold, Todd W.; Austin, Jane; Stafford, Joshua D.

    2015-01-01

    Population status and habitat use of yellow rails (Coturnicops noveboracensis), Nelson's sparrows (Ammodramus nelsoni), and Le Conte's sparrows (A. leconteii) are poorly known, so standardized surveys of these species are needed to inform conservation planning and management. A protocol for monitoring secretive marsh birds exists; however, these species regularly call at night and may be missed during early morning surveys. We tested the effectiveness of autonomous recording units (hereafter, recording units) to survey these species by analyzing recorded vocalizations using bioacoustics software. We deployed 22 recording units at 54 sites in northern Minnesota and eastern North Dakota, USA, and conducted traditional broadcast surveys during May–June, 2010 and 2011. We compared detection probabilities between recording units and standard monitoring protocols using robust-design occupancy models. On average, recording units detected 0.59 (SE = 0.11) fewer Le Conte's sparrows, 0.76 (SE = 0.15) fewer Nelson's sparrows, and 1.01 (SE = 0.14) fewer yellow rails per survey than were detected using the standard protocol. Detection probabilities using the standard protocol averaged 0.95 (yellow rail; 95% CI = 0.86–0.98), 0.93 (Le Conte's sparrow; 95% CI = 0.78–0.98), and 0.89 (Nelson's sparrow; 95% CI = 0.56–0.98), but averaged 0.71 (yellow rail; 95% CI = 0.56–0.83), 0.61 (Le Conte's sparrow; 95% CI = 0.42–0.78), and 0.51 (Nelson's sparrow; 95% CI = 0.19–0.82) using recording units. Reduced detection by recording units was likely due to the ability of human listeners to identify birds calling at greater distances. Recording units may be effective for surveying nocturnal secretive marsh birds if investigators correct for differential detectability. Reduced detectability may be outweighed by the increased spatial and temporal coverage feasible with recording units.

  18. Importance of unit cells in accurate evaluation of the characteristics of graphene

    Energy Technology Data Exchange (ETDEWEB)

    Sabzyan, Hassan; Sadeghpour, Narges [Isfahan Univ. (Iran, Islamic Republic of). Dept. of Chemistry

    2016-08-01

    Effects of the size of the unit cell on energy, atomic charges, and phonon frequencies of graphene at the Γ point of the Brillouin zone are studied in the absence and presence of an electric field using density functional theory (DFT) methods (LDA and DFT-PBE functionals with Goedecker-Teter-Hutter (GTH) and Troullier-Martins (TM) norm-conserving pseudopotentials). Two types of unit cells containing n{sub c}=4-28 carbon atoms are considered. Results show that stability of graphene increases with increasing size of the unit cell. Energy, atomic charges, and phonon frequencies all converge above n{sub c}=24 for all functional-pseudopotentials used. Except for the LDA-GTH calculations, application of an electric field of 0.4 and 0.9 V/nm strengths does not change the trends with the size of the unit cell but instead slightly decreases the binding energy of graphene. Results of this study show that the choice of unit cell size and type is critical for calculation of reliable characteristics of graphene.

  19. Design and Evaluation of a Fully Implantable Control Unit for Blood Pumps

    Directory of Open Access Journals (Sweden)

    Kristin Unthan

    2015-01-01

    Full Text Available As the number of donor hearts is limited while more and more patients suffer from end stage biventricular heart failure, Total Artificial Hearts become a promising alternative to conventional treatment. While pneumatic devices sufficiently supply the patients with blood flow, the patient’s quality of life is limited by the percutaneous pressure lines and the size of the external control unit. This paper describes the development of the control unit of the ReinHeart, a fully implantable Total Artificial Heart. General requirements for any implantable control unit are defined from a technical and medical point of view: necessity of a Transcutaneous Energy Transmission, autonomous operation, safety, geometry, and efficiency. Based on the requirements, a prototype is designed; it incorporates a LiFePo4 battery pack with charger, a rectifier for transcutaneous energy transmission, the motor’s driver electronics, and a microcontroller which monitors and controls all functions. In validation tests, the control unit demonstrated a stable operation on TET and battery supply and a safe switching from one supply to the other. The overall mean efficiency is 14% on TET and 22% on battery supply. The control unit is suitable for chronic animal trials of the ReinHeart.

  20. Evaluation of Small Form Factor Fiber Optic Interconnects for the NASA Electronics Parts and Packaging Program (NEPP)

    Science.gov (United States)

    Ott, Melanie; Thomes, W. Joe; Blair, Diana; Chuska, Rick; Switzer, Rob

    2010-01-01

    The Diamond AVIM optical fiber connector has been used for over a decade in flight environments. AVIM which stands for Aviation Intermediate Maintenance is always referenced as a fiber optic connector type from the DIN (Deutsches Institut fur Normung) family of optical fiber connectors. The newly available Mini AVIM and DMI (Definition Multimedia Interface) connectors also by Diamond provide similar features as the high performance AVIM with the added benefits of being small form factor for board mount and internal box use where long connectors and strain relief can not be accommodated. Transceiver, fiber laser technology and receiver optic technology based on small sized constraints will benefit the most by the reduction in connector form factor. It is for this reason that the Mini AVIM is being evaluated for multimode and single mode optical fiber use in both fiber based and cable based packaging configurations. In a fiber based termination, there are no cable materials to bond to the connector. The only bonding that is conducted is the mounting of the fiber with epoxy to the connector ferrules (which are called DMI ferrules). In a cable configuration, the compatibility of the connector subcomponents along with the upjacketing materials of the cable around the fiber needs to be considered carefully for termination fabrication. Cabled terminations will show greater insertion loss and high probability of failures during thermal cycling testing. This is due to the stressing of the combination of materials that each have different Coefficients of Thermal Expansion (CTE's) and that are bonded together to the connector subcomponents. As the materials flex during thermal excursions, forces are applied to the termination and can make the system fail if the grouping of materials (per their CTE's) are not compatible and this includes cable materials, epoxies, ferrule and connector body components. For this evaluation, multimode 100 micron core step index fiber was used for

  1. Cardiometry: pioneering experience in assessment of the heart performance and evaluation of fatal arrhythmia risks in intensive care unit patients

    Directory of Open Access Journals (Sweden)

    Vladimir V. Chepenko

    2014-05-01

    Full Text Available In the paper presented is an application study of the heart performance phase mechanism with the use of the Cardiocode analyzer based on principles of cardiometry for evaluating iatrogenic complications caused by antiarrhythmic therapy and monitoring the quality of treatment of hemodynamic disorders in inhospital intensive care units. The aim of the study is a thorough estimation of the diagnostic and functional quality of the performance of the Cardiocode device and developing a new methodology of its application under the conditions of the intensive care units, when predicting fatal arrhythmia progression. 50 patients with true cardiogenic shock of different degrees of severity have been examined with Cardiocode. As a result, it is established that the application of the heart cycle phase analysis in diagnostics, hemodynamics evaluation and management with the medication and infusion therapy supported by the Cardiocode device allows reducing the mortality rate by 32 ± 3.4%.

  2. Evaluation of SPACE code for simulation of inadvertent opening of spray valve in Shin Kori unit 1

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seyun; Youn, Bumsoo [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    SPACE code is expected to be applied to the safety analysis for LOCA (Loss of Coolant Accident) and Non-LOCA scenarios. SPACE code solves two-fluid, three-field governing equations and programmed with C++ computer language using object-oriented concepts. To evaluate the analysis capability for the transient phenomena in the actual nuclear power plant, an inadvertent opening of spray valve in startup test phase of Shin Kori unit 1 was simulated with SPACE code. To evaluate the analysis capability for the transient phenomena in the actual nuclear power plant, an inadvertent opening of spray valve in startup test phase of Shin Kori unit 1 was simulated with SPACE code.

  3. Ventral medial prefrontal cortex and person evaluation: forming impressions of others varying in financial and moral status.

    Science.gov (United States)

    Cloutier, Jasmin; Gyurovski, Ivo

    2014-10-15

    The current study investigated ventromedial prefrontal cortex (VMPFC) activity during impression formation of individuals varying on distinct dimensions of social status. In a block-design functional magnetic resonance imaging (fMRI) experiment, participants were presented with photographs of faces paired with a colored background indicating their lower, same, or higher financial status, or lower, same, or higher moral status. Participants were asked to form an impression of the targets, but were not instructed to explicitly evaluate them based on social status. Building on previous findings (Cloutier, Ambady, Meagher, & Gabrieli, 2012), a region of interest analysis revealed the interaction of status dimension and level in VMPFC, finding not only preferential response to targets with higher compared to lower moral status as previously demonstrated, but also greater response to targets with lower compared to higher financial status. The implications of these results are discussed with an emphasis towards better understanding the impact of social status on social cognition and uncovering the neural substrates of person evaluation.

  4. CRADA NFE-08-01456 Evaluation of Alumina-Forming Austenitic Stainless Steel Alloys in Industrial Gas Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Brady, Michael P [ORNL; Pint, Bruce A [ORNL; Unocic, Kinga A [ORNL; Yamamoto, Yukinori [ORNL; Kumar, Deepak [ORNL; Lipschutz, Mark D. [Solar Turbines, Inc.

    2011-09-01

    Oak Ridge National Laboratory (ORNL) and Solar Turbines Incorporated (Solar) participated in an in-kind cost share cooperative research and development agreement (CRADA) effort under the auspices of the Energy Efficiency and Renewable Energy (EERE) Technology Maturation Program to explore the feasibility for use of developmental ORNL alumina-forming austenitic (AFA) stainless steels as a material of construction for industrial gas turbine recuperator components. ORNL manufactured lab scale foil of three different AFA alloy compositions and delivered them to Solar for creep properties evaluation. One AFA composition was selected for a commercial trial foil batch. Both lab scale and the commercial trial scale foils were evaluated for oxidation and creep behavior. The AFA foil exhibited a promising combination of properties and is of interest for future scale up activities for turbine recuperators. Some issues were identified in the processing parameters used for the first trial commercial batch. This understanding will be used to guide process optimization of future AFA foil material production.

  5. Evaluation of Bacterial Contamination of Water Supply in Dental Unit Water Lines at Zahedan Dental School 2008

    Directory of Open Access Journals (Sweden)

    Mollashahi Leila

    2010-03-01

    Full Text Available Background: Assessment of microbial contamination in dental unit waterlines has been focused on because of high risk of dangerous infections in immunocompromised patients. The purpose of this study was to evaluate the bacterial contamination of water supply in dental unit water lines at Zahedan Dental School.Materials and Methods: In this descriptive analytical study we investigated 400 water samples collected from four parts of each unit including air/water syringe, turbine handpiece (before & after flushing, cup filler and 1 water sample collected from city water reservoir in Zahedan faculty of dentistry during 2008. Water samples were taken on Saturdays (the first working day in a week and Wednesdays (the last working day in a week, before and after treatment on the same unit. Samples were transported in closed sterile containers to microbiology laboratory. All samples were incubated on blood agar and McCankey plates for 72 hours at 37°C. Bacterial contamination were then evaluted. Data were analyzed by ANOVA and t-test.Results: Total mean bacterial count was 6914 cfu/ml. Mean bacterial contamination on Saturdays (8859 cfu/ml were higher than Wednesdays (4969 cfu/ml. Mean bacterial contamination before treatment was (5155 cfu/ml less than the end of treatment (8673 cfu/ml on the same unit. Mean bacterial contaminations of prosthetics clinic (13439cfu/ml was higher than other clinics. The mean of periodentology clinic bacterial contaminations (3012 cfu/ml was the least.Conclusion: The result of this study demonstrated that microbiological level of dental unit water lines is high. The dentists must be aware of the high level of microorganisms in the dental unit's water and thus minimize the risk of infection in both staff and patients.

  6. Planning for a smooth transition: evaluation of a succession planning program for prospective nurse unit managers.

    Science.gov (United States)

    Manning, Vicki; Jones, Alan; Jones, Pamela; Fernandez, Ritin S

    2015-01-01

    The current and projected nurse workforce shortage has created significant pressure on health care organizations to examine their approach to managing talent. This includes the need for strategic development of new formal leaders. This article reports on a succession planning program for prospective nursing unit managers. Eight prospective management candidates participated in a Future Nursing Unit Managers program. The effectiveness of the program was measured through a comparison of pre- and postprogram surveys relating to participants' perception of personal managerial and leadership skills. Significant differences in scores from baseline to 6-month follow-up surveys were observed in the participants' confidence in undertaking the nursing unit manager role and in their management skills. Investment in structured programs to prepare nurses for leadership roles is strongly recommended as a management workforce strategy.

  7. Evaluating the effects of woody biomass production for bioenergy on water quality and hydrology in the southeastern United States

    Science.gov (United States)

    Natalie Griffiths; C. Rhett Jackson; Menberu Bitew; Enhao Du; Kellie Vache' Jeffrey J. McDonnell; Julian Klaus; Benjamin M. Rau

    2016-01-01

    Forestry is a dominant industry in the southeastern United States, and there is interest in sustainably growing woody feedstocks for bioenergy in this region. Our project is evaluating the environmental sustainability (water quality, quantity) of growing and managing short-rotation (10-12 yrs) loblolly pine for bioenergy using watershed-scale experimental and modeling ...

  8. GATEWAY Demonstrations: Tuning Hospital Lighting: Evaluating Tunable LED Lighting at the Swedish Hospital Behavioral Health Unit in Seattle

    Energy Technology Data Exchange (ETDEWEB)

    Wilkerson, Andrea [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Davis, Robert G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Clark, Edward [ZGF Architects LLP, Seattle, WA (United States)

    2017-08-23

    The GATEWAY program evaluated a tunable LED lighting system installed in the new Swedish Medical Behavioral Health Unit in Seattle that incorporates color-tunable luminaires in common areas, and uses advanced controls for dimming and color tuning, with the goal of providing a better environment for staff and patients. The report reviews the design of the tunable lighting system, summarizes two sets of measurements, and discusses the circadian, energy, and commissioning implications as well as lessons learned from the project.

  9. A quantative evaluation of the reformulated 1996 path-goal theory of work unit leadership via structural equation modelling

    OpenAIRE

    Howieson, William B

    2008-01-01

    In 1996, Professor Robert J House published a reformulated Path-Goal Theory of Work Unit Leadership, based on his earlier 1971 and 1974 theories. Path-goal leadership attempts to explain the impact that leader behaviour has on subordinate motivation, satisfaction and performance. The aim of this context-specific study is to evaluate this reformulated ‘1996 Theory’ via Structural Equation Modelling with engineers from the Royal Air Force as the primary data source. This th...

  10. Interleukin-10 inhibits burst-forming unit-erythroid growth by suppression of endogenous granulocyte-macrophage colony-stimulating factor production from T cells.

    Science.gov (United States)

    Oehler, L; Kollars, M; Bohle, B; Berer, A; Reiter, E; Lechner, K; Geissler, K

    1999-02-01

    Numerous cytokines released from accessory cells have been shown to exert either stimulatory or inhibitory growth signals on burst-forming unit-erythroid (BFU-E) growth. Because of its cytokine synthesis-inhibiting effects on T cells and monocytes, interleukin-10 (IL-10) may be a potential candidate for indirectly affecting erythropoiesis. We investigated the effects of IL-10 on BFU-E growth from normal human peripheral blood mononuclear cells (PBMC) using a clonogenic progenitor cell assay. The addition of recombinant human IL-10 to cultures containing recombinant human erythropoietin suppressed BFU-E growth in a dose-dependent manner (by 55.2%, range 47.3-63.3%, p cultivating highly enriched CD34+ cells. BFU-E growth from PBMC also was markedly suppressed in the presence of a neutralizing anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) antibody (by 48.7%, range 32.9-61.2% inhibition,p < 0.01), but not by neutralizing antibodies against granulocyte colony-stimulating factor and interleukin-3. This suggests a stimulatory role of endogenously released GM-CSF on BFU-E formation. Also, the addition of exogenous GM-CSF completely restored IL-10-induced suppression of BFU-E growth. To determine the cellular source of GM-CSF production, we analyzed GM-CSF levels in suspension cultures containing PBMC that were either depleted of monocytes or T cells. Monocyte-depleted PBMC showed spontaneous production of increasing amounts of GM-CSF on days 3, 5, and 7, respectively, which could be suppressed by IL-10, whereas GM-CSF levels did not increase in cultures containing T-cell-depleted PBMC. Our data indicate that IL-10 inhibits the growth of erythroid progenitor cells in vitro, most likely by suppression of endogenous GM-CSF production from T cells.

  11. Manufacture of Clinical-Grade Human Clonal Mesenchymal Stem Cell Products from Single Colony Forming Unit-Derived Colonies Based on the Subfractionation Culturing Method.

    Science.gov (United States)

    Yi, TacGhee; Kim, Si-na; Lee, Hyun-Joo; Kim, Junghee; Cho, Yun-Kyoung; Shin, Dong-Hee; Tak, Sun-Ji; Moon, Sun-Hwa; Kang, Ji-Eun; Ji, In-Mi; Lim, Huyn-Ja; Lee, Dong-Soon; Jeon, Myung-Shin; Song, Sun U

    2015-12-01

    Stem cell products derived from mesenchymal stem cells (MSCs) have been widely used in clinical trials, and a few products have been already commercialized. However, the therapeutic effects of clinical-grade MSCs are still controversial owing to mixed results from recent clinical trials. A potential solution to overcome this hurdle may be to use clonal stem cells as the starting cell material to increase the homogeneity of the final stem cell products. We have previously developed an alternative isolation and culture protocol for establishing a population of clonal MSCs (cMSCs) from single colony forming unit (CFU)-derived colonies. In this study, we established a good manufacturing practice (GMP)-compatible procedure for the clinical-grade production of human bone marrow-derived cMSCs based on the subfractionation culturing method. We optimized the culture procedures to expand and obtain a clonal population of final MSC products from single CFU-derived colonies in a GMP facility. The characterization results of the final cMSC products met our preset criteria. Animal toxicity tests were performed in a good laboratory practice facility, and showed no toxicity or tumor formation in vivo. These tests include single injection toxicity, multiple injection toxicity, biodistribution analysis, and tumorigenicity tests in vivo. No chromosomal abnormalities were detected by in situ karyotyping using oligo-fluorescence in situ hydridization (oligo-FISH), providing evidence of genetic stability of the clinical-grade cMSC products. The manufacture and quality control results indicated that our GMP methodology could produce sufficient clonal population of MSC products from a small amount of bone marrow aspirate to treat a number of patients.

  12. Mobile Units Supplementing Education (M.U.S.E.). Evaluation, ESEA Title III, Fiscal Year 1970.

    Science.gov (United States)

    Dodge County Schools, Fremont, NE.

    A project in Dodge County, Nebraska, from July 1, 1969, to June 30, 1970, used Mobile Units Supplementing Education (MUSE) under an Elementary and Secondary Education Act Title III grant. The primary objective of the pilot project and the operational grant was to demonstrate and explore the possibilities of bringing special and supplemental units…

  13. Evaluating Infection Prevention Strategies in Out-Patient Dialysis Units Using Agent-Based Modeling.

    Directory of Open Access Journals (Sweden)

    Joanna R Wares

    Full Text Available Patients receiving chronic hemodialysis (CHD are among the most vulnerable to infections caused by multidrug-resistant organisms (MDRO, which are associated with high rates of morbidity and mortality. Current guidelines to reduce transmission of MDRO in the out-patient dialysis unit are targeted at patients considered to be high-risk for transmitting these organisms: those with infected skin wounds not contained by a dressing, or those with fecal incontinence or uncontrolled diarrhea. Here, we hypothesize that targeting patients receiving antimicrobial treatment would more effectively reduce transmission and acquisition of MDRO. We also hypothesize that environmental contamination plays a role in the dissemination of MDRO in the dialysis unit. To address our hypotheses, we built an agent-based model to simulate different treatment strategies in a dialysis unit. Our results suggest that reducing antimicrobial treatment, either by reducing the number of patients receiving treatment or by reducing the duration of the treatment, markedly reduces overall colonization rates and also the levels of environmental contamination in the dialysis unit. Our results also suggest that improving the environmental decontamination efficacy between patient dialysis treatments is an effective method for reducing colonization and contamination rates. These findings have important implications for the development and implementation of future infection prevention strategies.

  14. Issues for an Evaluation of Freire-Inspired Programs in the United States and Puerto Rico.

    Science.gov (United States)

    Facundo, Blanca

    Paulo Freire is a Brazilian educator whose theories link educational processes with revolutionary political aims. This report describes attempts by predominantly Latino proponents of his theories to develop "liberating education" (educacion liberadora) in the United States and in Puerto Rico. Section 1 describes the national, political,…

  15. Antiroll Tank Evaluation for the United States Coast Guard 300-Foot Icebreaker (WAGB).

    Science.gov (United States)

    1981-06-01

    THE UNITED STATES Final COAST GUARD 300-FOOT ICEBREAKER (WAGB) 6 PERFORMING ORG. REPORT NUMBER 7, AUTHOR(e) 4. CONTRACT OR GRANT NUMBER(s) Harry D...quite good stabilizing characteris- tics. CONCLUSION The installation of the antiroll tank on the WAGB would help assure a mucl more tolerable roll

  16. Ileus development in the trauma/surgical intensive care unit: a process improvement evaluation.

    Science.gov (United States)

    Phipps, Marcy; Bush, Jeffrey A; Buhrow, Dianne; Tittle, Mary B; Singh, Deepak; Harcombe, Julianne; Riddle, Evanthia

    2011-01-01

    Ileus development has been associated with a wide range of complications among hospitalized patients, ranging from increased patient pain and discomfort to malnutrition, aspiration, delayed rehabilitation, and sepsis. This article examines factors that appeared to correlate with an increase in ileus development among patients in a trauma/surgical intensive care unit, with the goal of preventing the condition through nursing practice changes.

  17. A collaborative Canadian-United Kingdom evaluation of an immunohistochemistry protocol to diagnose bovine spongiform encephalopathy

    Science.gov (United States)

    Bovine spongiform encephalopathy is a transmissible spongiform encephalopathy of domestic cattle. The disorder was reported in the United Kingdom in the late 1980s and was associated with recycling of ruminant byproducts in cattle feed. In 1996, the bovine disease was reported to be the cause of a...

  18. Buying time II: an economic evaluation of a joint NHS/Social Services residential rehabilitation unit for older people on discharge from hospital.

    Science.gov (United States)

    Ellis, Annie; Trappes-Lomax, Tessa; Fox, Mary; Taylor, Rod; Power, Michael; Stead, Jonathan; Bainbridge, Ian

    2006-03-01

    The study's aim was to investigate the cost-effectiveness of an NHS/Social Services short-term residential rehabilitation unit (a form of intermediate care) for older people on discharge from community hospital compared with 'usual' community services. An economic evaluation was conducted alongside a prospective controlled trial, which explored the effectiveness of a rehabilitation unit in a practice setting. The aim of the unit was to help individuals regain independence. A matched control group went home from hospital with the health/social care services they would ordinarily receive. The research was conducted in two matched geographical areas in Devon: one with a rehabilitation unit, one without. Participants were recruited from January 1999 to October 2000 in 10 community hospitals and their eligibility determined using the unit's strict inclusion/exclusion criteria, including 55 years or older and likely to benefit from a short-term rehabilitation programme: potential to improve, realistic, achievable goals, motivation to participate. Ninety-four people were recruited to the intervention and 112 to the control group. Details were collated of the NHS and Social Services resources participants used over a 12-month follow-up. The cost of the resource use was compared between those who went to the unit and those who went straight home. Overall, costs were very similar between the two groups. Aggregated mean NHS/Social Services costs for the 12 months of follow-up were pound 8542.28 for the intervention group and pound 8510.68 for the control. However, there was a clear 'seesaw' effect between the NHS and Social Services: the cost of the unit option fell more heavily on Social Services (pound 5011.56, whereas pound 3530.72 to the NHS), the community option more so on the NHS (pound 5146.74, whereas pound 3363.94 to Social Services). This suggests that residential rehabilitation for older people is no more cost-effective over a year after discharge from community

  19. Therapeutic education unit for heart failure: setting-up and difficulties. Initial evaluation of the I-CARE programme.

    Science.gov (United States)

    Juillière, Yves; Jourdain, Patrick; Roncalli, Jérome; Boireau, Amélie; Guibert, Hélène; Lambert, Hélène; Spinazze, Laure; Jondeau, Guillaume; Sonnier, Pierre; Rouanne, Céline; Bidet, Angélique; Sandrin-Berthon, Brigitte; Trochu, Jean-Nöel

    2009-01-01

    Education programmes are required in chronic diseases. The insuffisance cardiaque : éducation thérapeutique (I-CARE) programme was developed in France to promote the setting-up of therapeutic education units for chronic heart failure. To evaluate the setting-up of such units, assessing the influence of training on the creation and organization of the unit, the problems encountered and the contribution of the dedicated educational tools. We submitted a questionnaire to the first 136 trained centres. The questionnaire was divided into two sections: one section dealing with educational practices and the other with the advantages and disadvantages of the tools provided. The participation rate reached 69.1%. Seventy-four centres (78.7%) declared themselves to be active in therapeutic education. Unit educational activities determined an educational diagnosis (89.2% of the centres) and provided education by means of collective workshops (73.0%) or one-to-one teaching sessions (75.7%). A complete education programme for a patient consisted of a median of four sessions (25th-75th percentile, 2-5 sessions) and lasted for a median of 6 h (25th-75th percentile, 4-10 h). The education team was multidisciplinary and usually included a nurse (93.2%), a dietician (78.4%), a cardiologist (71.6%) and a physiotherapist (40.5%). Heart failure educational tools were used only in part in most centres (89.2%). All advantages and disadvantages were recorded. This first evaluation of the setting-up of therapeutic education units in the I-CARE programme has yielded promising results, despite expected difficulties. The effects of therapeutic education on the behaviour of heart failure patients remain to be determined.

  20. Comparability of the Vineland Social Maturity Scale and the Vineland Adaptive Behavior Scale--survey form with infants evaluated for developmental delay.

    Science.gov (United States)

    Raggio, D J; Massingale, T W

    1990-10-01

    The Vineland Social Maturity Scale and its revision, the Vineland Adaptive Behavior Scale-Survey Form, were evaluated with infants referred for suspected developmental delay. Since the latter is being used more often by psychologists in evaluation and placement of children in the age group of birth to two years, comparative studies must ensure appropriate placement of children observed to have developmental delays. The present study indicated significantly higher over-all adaptive functioning on the Vineland Adaptive Behavior Scale-Survey Form for 33 black and 11 white infants of mean age 12 mo. than on the original Vineland scales. Substituting the Survey Form for the original Vineland scales when evaluating developmentally delayed infants is questionable. These results are also noteworthy in that children whose Vineland Social Maturity scaled scores make them eligible for special services would be excluded if the revised form were used in the evaluation process.

  1. Evaluation of blood reservation and use for caesarean sections in a tertiary maternity unit in south western Nigeria

    Directory of Open Access Journals (Sweden)

    Oshodi Yussuf A

    2010-09-01

    Full Text Available Abstract Background Haemorrhage from obstetric causes is the most common cause of maternal mortality in the developing world. Prevention of mortality from haemorrhage will necessarily involve prompt blood transfusions among other life saving measures. There are however limited stocks of fresh or stored blood in many health care facilities in Sub Saharan Africa. Caesarean section has been identified as a common indication for blood transfusion in obstetrics practice and its performance is often delayed by non availability of blood in our centre. An evaluation of blood reservation and use at caesarean sections in a tertiary maternity unit in Lagos, south western Nigeria should therefore assist in formulating the most rational blood transfusion policies. Methods Case records of 327 patients who had elective and emergency caesarian sections at the Lagos State University Teaching Hospital between 1st October and 31st December 2007 were reviewed. Data pertaining to age, parity, booking status, type and indication for Caesarean section, pre- and post-operative packed cell volume, blood loss at surgery, units of blood reserved in the blood bank, unit(s of blood transfused and duration of hospital stay was extracted and the data analysed. Results There were 1056 deliveries out of which 327 (31% were by Caesarean section. During the study period, a total of 654 units of blood were reserved in the blood bank and subsequently made available in theatre. Out of this number, only 89 (13.6% were transfused to 41 patients. Amongst those transfused, twenty-six (54% were booked and 31 (75.6% had primary caesarian section. About 81% of those transfused had emergency caesarean section. The most common indication for surgery among those transfused were placenta praevia (9 patients with 21 units of blood and cephalo-pelvic disproportion (8 patients with 13 units. Conclusion Even though a large number of units of blood was reserved and made available in the theatre at

  2. Evaluation of the use of moss transplants (Pseudoscleropodium purum) for biomonitoring different forms of air pollutant nitrogen compounds.

    Science.gov (United States)

    Varela, Z; García-Seoane, R; Arróniz-Crespo, M; Carballeira, A; Fernández, J A; Aboal, J R

    2016-06-01

    We investigated whether three different types of moss transplants (devitalized moss bags with and without cover and auto-irrigated moss transplants) are suitable for use as biomonitors of the deposition of oxidised and/or reduced forms of N. For this purpose, we determined whether the concentration of atmospheric NO2 was related to the % N, δ(15)N and the activity of the enzyme biomarkers phosphomonoesterase (PME) and nitrate reductase (NR) in the tissues of moss transplants. We exposed the transplants in 5 different environments of Galicia (NW Spain) and Cataluña (NE Spain): industrial environments, urban and periurban environments, the surroundings of a cattle farm and in a monitoring site included in the sampling network of the European Monitoring Programme. The results showed that the moss in the auto-irrigated transplants was able of incorporating the N in its tissues because it was metabolically active, whereas in devitalized moss bags transplants, moss simply intercepts physically the N compounds that reached it in particulate or gaseous form. In addition, this devitalization could limit the capacity of moss to capture gaseous compounds (i.e. reduced N) and to reduce the oxidised compounds that reach the specimens. These findings indicate that devitalized moss transplants cannot be used to monitor either oxidised or reduced N compounds, whereas transplants of metabolically active moss can be used for this purpose. Finally, the NR and PME biomarkers should be used with caution because of the high variability in their activities and the limits of quantification should be evaluated in each case.

  3. Guidelines for the Psychosocial Evaluation of Living Unrelated Kidney Donors in the United States

    National Research Council Canada - National Science Library

    Dew, M. A; Jacobs, C. L; Jowsey, S. G; Hanto, R; Miller, C; Delmonico, F.L

    2007-01-01

    ..., in Washington, DC, to develop guidelines for the psychosocial evaluation of prospective living kidney donors who have neither a biologic nor longstanding emotional relationship with the transplant candidate...

  4. Flattening filter free beams from TrueBeam and Versa HD units: Evaluation of the parameters for quality assurance.

    Science.gov (United States)

    Fogliata, Antonella; Fleckenstein, Jens; Schneider, Frank; Pachoud, Marc; Ghandour, Sarah; Krauss, Harald; Reggiori, Giacomo; Stravato, Antonella; Lohr, Frank; Scorsetti, Marta; Cozzi, Luca

    2016-01-01

    Flattening filter free (FFF) beams generated by medical linear accelerators are today clinically used for stereotactical and non-stereotactical radiotherapy treatments. Such beams differ from the standard flattened beams (FF) in the high dose rate and the profile shape peaked on the beam central axis. Definition of new parameters as unflatness and slope for FFF beams has been proposed based on a renormalization factor for FFF profiles. The present study aims to assess the dosimetric differences between FFF beams generated by linear accelerators from different vendors, and to provide renormalization and parameter data of the two kinds of units. Dosimetric data from two Varian TrueBeam and two Elekta Versa HD linear accelerators, all with 6 and 10 MV nominal accelerating potentials, FF and FFF modes have been collected. Renormalization factors and related fit parameters according to Fogliata et al. ["Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy," Med. Phys. 39, 6455-6464 (2012)] have been evaluated for FFF beams of both units and energies. Unflatness and slope parameters from profile curves were evaluated. Dosimetric differences in terms of beam penetration and near-the-surface dose were also assessed. FFF profile parameters have been updated; renormalization factors and unflatness from the Varian units are consistent with the published data. Elekta FFF beam qualities, different from the Varian generated beams, tend to express similar behaviour as the FF beam of the corresponding nominal energy. TPR20,10 for 6 and 10 MV FF and FFF TrueBeam beams are 0.665, 0.629 (6 MV) and 0.738, 0.703 (10 MV). The same figures for Versa HD units are 0.684, 0.678 (6 MV) and 0.734, 0.721 (10 MV). Renormalization factor and unflatness parameters evaluated from Varian and Elekta FFF beams are provided, in particular renormalization factors table and fit parameters.

  5. THE USE OF THE EXPERIMENT PLANNING METHOD TO EVALUATE THE ACCURACY OF FLEXIBLE UNITS IDENTIFICATION

    Directory of Open Access Journals (Sweden)

    O. Y. Yehorov

    2015-10-01

    Full Text Available Purpose. The identification of rolling stock on the railroads is an integral part of many automation systems as trains in general and cars separately. Various information management systems at sorting yards require the operational information about the object while performing the manufacturing operations. The improvement of the determination accuracy of different parameters characterizing the rolling stock, leads to the immediate quality progress in the traffic volumes management. The aim of the paper is to develop a method to estimate the errors of determination the interaxle distance of the flexible units in the control section using the point path-control transducer for future identification of cars and locomotives. Methodology. To achieve this goal the simulation method and experiment planning were used. The simulation model allowing determining the time intervals between the collisions of wheelset of movable units in point path-control transducer on the control section with variable characteristics of identification devices was developed. The values of the time intervals obtained with using the simulation mode were applied in the method of experiment planning to the final target. Findings. The calculated analytical values of the errors of the interaxle distances do not have the significant differences from values obtained using the simulation model. It makes possible to use the received functional dependence to estimate the possible errors in the identification of rolling stock. The results of this work can be used to identify separate flexible units, and trains in general. Originality. The functional dependence of the error of the interaxle distance error from the fixing point of the wheel path-control transducer, the distance between the sensors and the measured distance was derived using a previously conducted research of the factors influencing the error in determining the interaxle distance of the movable units, and developed

  6. Evaluation of Antimicrobial and Antifungal efficacy of Chitosan as endodontic irrigant against Enterococcus Faecalis and Candida Albicans Biofilm formed on tooth substrate

    OpenAIRE

    Yadav, Pankaj; Chaudhry, Sarika; Saxena, Rajendra K.; Talwar, Sangeeta; Yadav, Sudha

    2017-01-01

    Background Bacterial biofilms formed on the root canal wall are often difficult to remove. This study aimed to evaluate the cytotoxic effect and antibacterial efficacy of chitosan when used as root canal irrigant against E. Faecalis and Candida albicans biofilm formed on tooth substrate. Material and Methods The present study evaluated antibacterial effect of 0.25% Chitosan, 0.5% Chitosan, 2% chlorhexidine and 3% sodium hypochlorite against Enterococcus faecalis and Candida Albicans. Agar-wel...

  7. Experimental Evaluation of a Total Heat Recovery Unit with Polymer Membrane Foils

    DEFF Research Database (Denmark)

    Fang, Lei; Yuan, Shu; Nie, Jinzhe

    2014-01-01

    . The test was also conducted in isothermal conditions to observe the moisture transfer performance of the polymer membrane heat exchanger. The results of the experiment shows that total heat recovery equipment tested can recover up to 60 % of the total heat from the ventilation air. Around 87......A laboratory experimental study was conducted to investigate the energy performance of a total heat recovery unit using a polymer membranes heat exchanger. The study was conducted in twin climate chambers. One of the chambers simulated outdoor climate conditions and the other simulated the climate...... on the measured temperature and humidity values, the temperature, humidity, and enthalpy efficiencies of the total heat recovery unit were calculated. The experiment was conducted in different combinations of outdoor climate conditions simulating warm and humid outdoor climates and air-conditioned indoor climate...

  8. Evaluating the energy consumed for water use in the United States

    Science.gov (United States)

    Sanders, Kelly T.; Webber, Michael E.

    2012-09-01

    This letter consists of a first-order analysis of the primary energy embedded in water in the United States. Using a combination of top-down sectoral assessments of energy use together with a bottom-up allocation of energy-for-water on a component-wise and service-specific level, our analysis concludes that energy use in the residential, commercial, industrial and power sectors for direct water and steam services was approximately 12.3 ± 0.3 quadrillion BTUs or 12.6% of the 2010 annual primary energy consumption in the United States. Additional energy was used to generate steam for indirect process heating, space heating and electricity generation.

  9. Qualification of Daiichi Units 1, 2, and 3 Data for Severe Accident Evaluations - Process and Illustrative Examples from Prior TMI-2 Evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Rempe, Joy Lynn [Idaho National Lab. (INL), Idaho Falls, ID (United States); Knudson, Darrell Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    The accidents at the Three Mile Island Unit 2 (TMI-2) Pressurized Water Reactor (PWR) and the Daiichi Units 1, 2, and 3 Boiling Water Reactors (BWRs) provide unique opportunities to evaluate instrumentation exposed to severe accident conditions. Conditions associated with the release of coolant and the hydrogen burn that occurred during the TMI-2 accident exposed instrumentation to harsh conditions, including direct radiation, radioactive contamination, and high humidity with elevated temperatures and pressures. As part of a program initiated in 2012 by the Department of Energy Office of Nuclear Energy (DOE-NE), a review was completed to gain insights from prior TMI-2 sensor survivability and data qualification efforts. This initial review focused on the set of sensors deemed most important by post-TMI-2 instrumentation evaluation programs. Instrumentation evaluation programs focused on data required by TMI-2 operators to assess the condition of the reactor and containment and the effect of mitigating actions taken by these operators. In addition, prior efforts focused on sensors providing data required for subsequent forensic evaluations and accident simulations. To encourage the potential for similar activities to be completed for qualifying data from Daiichi Units 1, 2, and 3, this report provides additional details related to the formal process used to develop a qualified TMI-2 data base and presents data qualification details for three parameters: primary system pressure; containment building temperature; and containment pressure. As described within this report, sensor evaluations and data qualification required implementation of various processes, including comparisons with data from other sensors, analytical calculations, laboratory testing, and comparisons with sensors subjected to similar conditions in large-scale integral tests and with sensors that were similar in design to instruments easily removed from the TMI-2 plant for evaluations. As documented

  10. Evaluating the quality of patient leaflets about renal replacement therapy across UK renal units.

    Science.gov (United States)

    Winterbottom, Anna; Conner, Mark; Mooney, Andrew; Bekker, Hilary L

    2007-08-01

    Enhancing patient participation is a priority for renal services. Good quality information is fundamental to facilitate patient involvement, but in other health contexts it has been found to be sub-optimal. This research aims to audit the provision of patient information by renal units and charities and to assess the quality of written information about dialysis treatment options. All UK renal units were sent a questionnaire about the patient information they provided. Renal units and charities that provided dialysis leaflets were asked to forward copies. Leaflet quality and content were assessed by a coding frame informed by information and decision aid checklists. Out of 105, 67 completed questionnaires were returned. Services provide patients with large amounts of information in several media (leaflets, meetings with nurses and patients, videos); computers were not used frequently. Out of 47, 32 units forwarded leaflets about dialysis, and 31 different leaflets. Most leaflets were difficult to understand and rarely included risk information or treatment limitations. No leaflets included techniques to assist patient involvement or decision-making; their primary goal was to inform. These data suggest an unsystematic pattern of information provision across the UK. Vast resources have been spent on providing information to patients that is difficult to comprehend and incomplete. Research needs to identify which resources are effective in meeting patient needs and at what point in their illness. A centralized system to guide renal services in the design and development of information resources may help meet the differing goals of education, choice facilitation and preparation for self-management.

  11. Evaluation of noise in a neonatal unit at a university hospital

    Directory of Open Access Journals (Sweden)

    Ariadne Pinheiro Nazario

    2015-05-01

    Full Text Available Objective: To identify and measure the main sources of noise, to determine the levels of ambient noise and to know the perception of employees about noise in a Neonatal Unit. Material and method: A quantitative study developed in a Neonatal Unit School Hospital, Paraná, Brazil, conducted in three steps: identification of the main sources of noise and subsequent measure; interview with the multidisciplinary team about the perception of noise in the unit; and dimensioning noise ambient for two non-consecutive weeks. Results: The main sources of noise were: monitor and equipment alarms, open water faucets, trash can lids, among others. The mean of the two weeks period was: Leq 44.4 dB, Lmax 104.5 dB, Lmin 40 dB and Lpeak 144.8 dB. Employees acknowledged that intense noise is prejudicial to them and to babies. Conclusion: It was found that the mean value of the noise is within the recommended, but with very high levels of Lpeak and Lmax.

  12. Formulation, characterization and in vitro evaluation of floating microspheres of famotidine as a gastro retentive dosage form

    Directory of Open Access Journals (Sweden)

    Jain Abhishek

    2009-01-01

    Full Text Available The present study involves preparation and evaluation of floating microspheres using famotidine (FM as a model drug for prolongation of the gastric retention time. The microspheres were prepared by the solvent evaporation method using different polymers, i.e. acrycoat S100 and cellulose acetate. The size or average diameter (d avg and surface morphology of the prepared microspheres were recognized and characterized by the optical and scanning electron microscopic methods, respectively. In vitro drug release studies were performed and the drug release kinetics were evaluated using the linear regression method. Effects of the stirring rate during preparation, polymer concentration on the size of the microspheres and drug release were also observed. The prepared microspheres exhibited prolonged drug release (18 h and remained buoyant for more than 12 h. The mean particle size increased and the drug release rate decreased at a higher polymer concentration. No significant effect of the stirring rate during preparation on drug release was observed. In vitro studies demonstrated a diffusion-controlled drug release from the microspheres. The objective of the present study was to develop floating microspheres of FM in order to achieve an extended retention in the upper gastrointestinal tract, which may result in enhanced absorption and thereby improved bioavailability. The prepared microspheres were evaluated for particle size, in vitro release and buoyancy and incorporation efficiency. The effect of various formulation variables on the size and drug release was investigated. In vitro drug release studies were performed and the drug release kinetics were evaluated using the linear regression method. FM was obtained as a gift sample from Intas Pharmaceuticals, Ahmedabad, India. Polyvinyl alcohol was obtained from S.D. Fine Chemicals Ltd., Mumbai, India. Dichloromethane, acrycoat S100, cellulose acetate and Tween 80 were obtained from Central Drug House (P

  13. Harm Reduction Unit of the City of Santo André, São Paulo State, Brazil: An Evaluation

    Directory of Open Access Journals (Sweden)

    Silvia Moreira da Silva

    2010-12-01

    Full Text Available The Harm Reduction Unit (HRU in Santo André (São Paulo State was created to improve the health of people who either live or work on the streets: drug users, commercial sex workers (male and female, men who have sex with men, sexually exploited adolescents, transsexuals, transvestites, lesbians, and women working in brothels. This project was undertaken to evaluate the HRU from the perspective of its users. A semi-structured interview was administered to nineteen users from different segments of the populations served by the unit. The major weaknesses of the HRU were felt to be its inconsistent presence in some areas and the absence of psychologists to provide follow-up care. The unit was seen as promoting better health, increased use of condoms, reduction in drug usage, increased access and use of health care services, and less sharing of equipment used in drug consumption. Users see the HRU as a sympathetic presence whose ongoing work provides them with a sense of security and protection. The impact of the HRU went beyond harm reduction; users reported transformative changes such as increased awareness of their social rights and knowledge about how those rights can be demanded. Users had been given new tools to face their problems and seek access to education, work, and housing. Key words: harm reduction, illegal drugs, health service evaluation, social problems

  14. Evaluation of ionization techniques for mass spectrometric detection of contact allergenic hydroperoxides formed by autoxidation of fragrance terpenes.

    Science.gov (United States)

    Nilsson, J; Carlberg, J; Abrahamsson, P; Hulthe, G; Persson, B-A; Karlberg, A-T

    2008-11-01

    Hydroperoxides formed by autoxidation of common fragrance terpenes are strong allergens and known to cause allergic contact dermatitis (ACD), a common skin disease caused by low molecular weight chemicals. Until now, no suitable methods for chemical analyses of monoterpene hydroperoxides have been available. Their thermolability prohibits the use of gas chromatography and their low UV-absorption properties do not promote sensitive analytical methods by liquid chromatography based on UV detection. In our study, we have investigated different liquid chromatography/mass spectrometry (LC/MS) ionization techniques, electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), and atmospheric pressure photoionization (APPI), for detection of hydroperoxides from linalool and limonene.Flow injection analysis was used to evaluate the three different techniques to ionize the monoterpene hydroperoxides, linalool hydroperoxide and limonene hydroperoxide, by estimating the signal efficacy under experimental conditions for positive and negative ionization modes. The intensities for the species [M+H]+ and [M+H-H2O]+ in positive ionization mode and [M-H]- and [M-H-H2O]- in negative ionization mode were monitored. It was demonstrated that the mobile phase composition and instrumental parameters have major influences on the ionization efficiency of these compounds. ESI and APCI were both found to be appropriate as ionization techniques for detection of the two hydroperoxides. However, APPI was less suitable as ionization technique for the investigated hydroperoxides.

  15. Formulation and in vitro evaluation of taste-masked oro-dispersible dosage form of diltiazem hydrochloride

    Directory of Open Access Journals (Sweden)

    Swati Changdeo Jagdale

    2011-12-01

    Full Text Available Diltiazem hydrochloride is a calcium channel blocker generally indicated for the treatment of angina and hypertension, and it is extensively metabolized due to the hepatic metabolism. Formulation of diltiazem hydrochloride into an oro-dispersible dosage form can provide fast relief with higher bioavailability. The bitter taste of the drug should be masked to formulate it in a palatable form. In the present work, an attempt was made to mask the taste by complexation technique, with a formulation into an oro-dispersible dosage form, using superdisintegrants Doshion P544, crospovidone (CP and sodium starch glycolate (SSG. The complexes of diltiazem hydrochloride with β-CD (1:1 molar ratio were prepared by kneading, co-evaporation, co-grounding, freeze-drying and melting methods. Phase solubility showed stability constant 819.13M-1. Prepared inclusion complexes were evaluated for taste masking and characterized by I.R, XRD, DSC. Using the drug β-CD complex, oro-dispersible tablets were prepared and evaluated for hardness, friability, weight variation, thickness, disintegrating time (DT, dissolution rate and taste. Formulations with 4 % Doshion, 8 % CP and 4 % SSG showed DT of 0.54, 0.35 and 1.23 minutes, respectively.O cloridrato de diltiazem é bloqueador do canal de cálcio geralmente indicado para o tratamento de angina e de hipertensão e é extensamente biotransformado devido ao metabolismo hepático. A formulação do cloridrato de diltiazem em orodispersão pode prover rápida liberação com maior biodisponibilidade. O sabor amargo do fármaco deve ser mascarado para ser formulado em forma palatável. No presente trabalho tentou-se mascarar o sabor pela técnica de complexação, com uma orodispersão, usando superdesintegrantes, como Doshio P544, crospivodina (CP e glicolato de amido sódico (SSG. Os complexos de cloridrato de diltiazem com β-CD (razão molar 1:1 foram preparados por mistura, coevaporação, comoagem, liofilização e m

  16. Evaluation of dynamic fracture toughness for Yong Gwang unit 5 reactor pressure vessel materials (Baseline Tests)

    Energy Technology Data Exchange (ETDEWEB)

    Chi Se Hwan; Kim, Joo Hag; Hong, Jun Hwa; Kwon, Sun Chil; Lee, Bong Sang [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-10-01

    The dynamic fracture toughness (K{sub d}) of intermediate shell and its weld in SA 508 CI. 3 Yong Gwang 5 reactor pressure vessel was determined and evaluated. Precracked thirty six Charpy specimens were tested by using an instrumented impact tester. The purpose of present work is to evaluate and confirm the un-irradiated dynamic fracture toughness and to provide pre-irradiation baseline data for future evaluation on dynamic fracture toughness change during operation. 18 refs., 5 figs., 5 tabs. (Author)

  17. Scaffold oriented synthesis. Part 4: design, synthesis and biological evaluation of novel 5-substituted indazoles as potent and selective kinase inhibitors employing heterocycle forming and multicomponent reactions.

    Science.gov (United States)

    Akritopoulou-Zanze, Irini; Wakefield, Brian D; Gasiecki, Alan; Kalvin, Douglas; Johnson, Eric F; Kovar, Peter; Djuric, Stevan W

    2011-03-01

    We report the synthesis and biological evaluation of 5-substituted indazoles as kinase inhibitors. The compounds were synthesized in a parallel synthesis fashion from readily available starting materials employing heterocycle forming and multicomponent reactions and were evaluated against a panel of kinase assays. Potent inhibitors were identified for Gsk3β, Rock2, and Egfr.

  18. EVALUATION OF THE TRADE RELATIONSHIP BETWEEN VIETNAM AND CHINA; VIETNAM AND UNITED STATES: A COMPARISON USING GRAVITY MODEL

    Directory of Open Access Journals (Sweden)

    Lien Thi Dinh

    2017-06-01

    Full Text Available This study aims to evaluate the determinants of trade relationship between two largest trading partners of Vietnam, United States and China. Using gravity model for time series data from 1986 to 2015, the study found that economic growth rate plays a crucial role in stimulating the trade flow. Both trade relationships fit with the practical approach of Heckscher-Ohlin theory, stating that trade flow increases between countries with different income levels. The most important finding of this study lines on the results regarding the impact of trade agreements. While United States-Vietnam bilateral agreement creates trade, the trade agreement between ASEAN and China produced trade diversion. As China expands its markets among ASEAN countries, Vietnam should diversify its export markets to improve its export flow.

  19. Energy Consumption Evaluation of United States Navy Leed Certified Building For Fiscal Year 2009

    Science.gov (United States)

    2010-01-01

    inclusion in this study was the ability to provide at least one full year of measured post - occupancy energy usage data for the entire LEED project...the Federal Energy Management Program. 4. Fowler, K. M. and Rauch, E. M. (2008). “A Post - Occupancy Evaluation of 12 GSA Buildings”. PNNL-17393...the Cascadia Region: A Post Occupancy Evaluation Report”. January 30, 2006. Cascadia Region Green Building Council. http://cascadiagbc.org

  20. Family Planning Evaluation. Abortion Surveillance Report--Legal Abortions, United States, April-June 1971.

    Science.gov (United States)

    Center for Disease Control (DHEW/PHS), Atlanta, GA.

    This report summarizes information received from collaborators in state health departments, hospitals, and other pertinent sources regarding abortions reported to the Center for Disease Control for the April-June quarter of 1971. Data in tabular and narrative form are given for abortion ratios by state, reported abortions by menstrual weeks of…

  1. Technical evaluation of RETS-required reports for Fort Calhoun Station Unit 1

    Energy Technology Data Exchange (ETDEWEB)

    Magleby, E.H.; Young, T.E.

    1985-06-24

    A review of the reports required by federal regulations and the plant-specific Radiological Effluent Technical Specifications (RETS) for operations conducted during 1983 was performed. The periodic reports reviewed for Fort Calhoun Station Unit 1 were two Semiannual Reports for Technical Specification 5.9.4. The principal review guidelines were the plant's specific RETS, NUREG-0133, ''Preparation of Radiological Effluent Technical Specifications for Nuclear Power Plants'', and NRC Guidance on the Review of the Process Control Programs. The Licensee's submitted reports were found to be reasonably complete and consistent with the review guidelines. 4 refs.

  2. Risk assessment analysis of the future technical unit dedicated to the evaluation and treatment of motor disabilities.

    Science.gov (United States)

    Grelier, S; Thetio, M; Quentin, V; Achache, V; Sanchez, N; Leroux, V; Durand, E; Pequignot, R

    2011-03-01

    The National Hospital of Saint Maurice (HNSM) for Physical Medicine and Rehabilitation aims at strengthening its position as a pivot rehabilitation and physical therapy center. The opening in 2011 of a new unit for the evaluation and treatment of motor disabilities meets this objective. This project includes several parts: clinical, financial, architectural, organizational, applied clinical research as well as dealing with medical equipments and information system. This study focuses on the risk assessment of this future technical unit. This study was conducted by a group of professionals working for the hospital. It started with the design of a functional model to better comprehend the system to be analyzed. Risk assessment consists in confronting this functional model to a list of dangers in order to determine the vulnerable areas of the system. Then the team designed some scenarios to identify the causes, securities barriers and consequences in order to rank the risks. The analysis targeted various dangers, e.g. political, strategic, financial, economical, marketing, clinical and operational. The team identified more than 70 risky scenarios. For 75% of them the criticality level was deemed initially tolerable and under control or unacceptable. The implementation of an action plan for reducing the level of risks before opening this technical unit brought the system down to an acceptable level at 66%. A year prior to opening this technical unit for the evaluation and treatment of motor disabilities, conducting this preliminary risk assessment, with its exhaustive and rigorous methodology, enabled the concerned professionals to work together around an action plan for reducing the risks. 2011 Elsevier Masson SAS. All rights reserved.

  3. Patient safety culture in a Dutch pediatric surgical intensive care unit: an evaluation using the Safety Attitudes Questionnaire.

    Science.gov (United States)

    Poley, Marten J; van der Starre, Cynthia; van den Bos, Ada; van Dijk, Monique; Tibboel, Dick

    2011-11-01

    Nowadays, the belief is widespread that a safety culture is crucial to achieving patient safety, yet there has been virtually no analysis of the safety culture in pediatric hospital settings so far. Our aim was to measure the safety climate in our unit, compare it with benchmarking data, and identify potential deficiencies. Prospective longitudinal survey study at two points in time. Pediatric surgical intensive care unit at a Dutch university hospital. All unit personnel. To measure the safety climate, the Safety Attitudes Questionnaire was administered to physicians, nurses, nursing assistants, pharmacists, technicians, and ward clerks in both May 2006 and May 2007. This questionnaire assesses caregiver attitudes through use of the six following scales: teamwork climate, job satisfaction, perceptions of management, safety climate, working conditions, and stress recognition. Earlier research showed that the Safety Attitudes Questionnaire has good psychometric properties and produced benchmarking data that can be used to evaluate strengths and weaknesses in a given clinical unit against peers. The response rates for the Safety Attitudes Questionnaire were 85% (May 2006) and 74% (May 2007). There were mixed findings regarding the difference between physicians and nurses: on three scales (i.e., teamwork climate, safety climate, and stress recognition), physicians scored better than nurses at both points in time. On another two scales (i.e., perceptions of management and working conditions), nurses consistently had higher mean scale scores. Probably due to the small number of physicians, only some of these differences between physicians and nurses reached the level of statistical significance. Compared to benchmarking data, scores on perceptions of management were higher than expected (p culture in our unit was good when compared to benchmark data, there is still room for improvement. This requires us to continue working on interventions intended to improve the safety

  4. Evaluation of a pulsed xenon ultraviolet light device for isolation room disinfection in a United Kingdom hospital.

    Science.gov (United States)

    Hosein, Ian; Madeloso, Rosie; Nagaratnam, Wijayaratnam; Villamaria, Frank; Stock, Eileen; Jinadatha, Chetan

    2016-09-01

    Pathogen transmission from contaminated surfaces can cause hospital-associated infections. Although pulsed xenon ultraviolet (PX-UV) light devices have been shown to decrease hospital room bioburden in the United States, their effectiveness in United Kingdom (UK) hospitals is less understood. Forty isolation rooms at the Queens Hospital (700 beds) in North London, UK, were sampled for aerobic bacteria after patient discharge, after manual cleaning with a hypochlorous acid-troclosene sodium solution, and after PX-UV disinfection. PX-UV device efficacy on known organisms was tested by exposing inoculated agar plates in a nonpatient care area. Turnaround times for device usage were recorded, and a survey of hospital staff for perceptions of the device was undertaken. After PX-UV disinfection, the bacterial contamination measured in colony forming units (CFU) decreased by 78.4%, a 91% reduction from initial bioburden levels prior to terminal cleaning. PX-UV exposure resulted in a 5-log CFU reduction for multidrug-resistant organisms (MDROs) on spiked plates. The average device turnaround time was 1 hour, with minimal impact on patient throughput. Ward staff were enthusiastic about device deployment, and device operators reported physical comfort in usage. PX-UV use decreased bioburden in patient discharge rooms and on agar plates spiked with MDROs. The implementation of the PX-UV device was well received by hospital cleaning and ward staff, with minimal disruption to patient flow. Copyright © 2016 Association for Professionals in Infection Control and Epidemiology, Inc. All rights reserved.

  5. Quantitative evaluation of flexibility in undergraduate engineering curricula in the United Arab Emirates

    Directory of Open Access Journals (Sweden)

    Naif A. Darwish

    2016-03-01

    Full Text Available In academia, smooth progression of students significantly depends on the way curricula are developed and organized. Curricula or study plans with high degree of interconnectivity between courses, multiple prerequisites, and hierarchically structured courses tend to complicate the smooth progress of the enrolled students. In this work, a rigorous quantitative relaxation indicator, developed and published elsewhere by the first author, has been applied to quantify the degree of stiffness and rigidity in undergraduate engineering curricula at the American University of Sharjah (AUS, the University of Sharjah (UOS, United Arab Emirates University (UAEU, and the Petroleum Institute (PI, which are the leading universities in the United Arab Emirates. Results indicate high rigidity (low relaxation indices due to high degree of interconnectivity between courses, specifically in the second year of the study plans. The chemical engineering curriculum at PI exhibited the least flexibility due to very strong pre-and-co-requisite ties while the civil & environmental curriculum at UAEU showed the highest flexibility. The curricula considered require immediate attention and reorganization in order to facilitate smooth sequential progress of the students from one semester to another. A list of courses that require relaxation of strong pre-and corequisites ties has been presented for each curriculum.

  6. Bone density: comparative evaluation of Hounsfield units in multislice and cone-beam computed tomography

    Directory of Open Access Journals (Sweden)

    Isabela Maria de Carvalho Crusoé Silva

    2012-12-01

    Full Text Available The aim of this study was to evaluate the validity of the bone density value of potential implant sites in HU obtained by a specific cone-beam computed tomography (CBCT device. In this study, the HU values obtained using a MSCT scanner were used as the gold standard. Twenty mandibles (40 potential implant sites were scanned using an MSCT scanner (Somatom Sensation 40 and a CBCT scanner (i-CAT. The MSCT images were evaluated using the Syngo CT Workplace software and the CBCT images, using the XoranCat software. The images were evaluated twice by three oral radiologists, at 60 day intervals. The trabecular bone density of the same area was evaluated on both images. Intraclass coefficients (ICC were calculated to examine the agreement between the examiners and between the two periods of evaluation. The bone density and area of the ROI were compared by the Student t test and Bland-Altman analysis. ICCs were excellent. The mean HU value obtained using CBCT (418.06 was higher than that obtained using MSCT (313.13, with a statistically significant difference (p < 0.0001. In addition, Bland-Altman analysis showed that the HU measures were not equivalent. In conclusion, the bone density in HU with CBCT images obtained using the device studied proved unreliable, since it was higher than that obtained using MSCT.

  7. Construction, evaluation and demonstration of mobile catalytic combustion units for destruction of methane and different odor pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Jannasch, Anna-Karin [Catator AB, Lund (Sweden)

    2012-02-15

    This project reports on the construction, the evaluation and the demonstration of novel, mobile small-scale (< 100 Nm{sup 3}/h) combustion units for reduction of methane and/or different odour pollutants (e.g. hydrogen sulfide, ammonia, VOC) existing in small concentrations in process air streams. The evaluated units include a regenerative (MeshRegenOx/MRO) and a recuperative, catalytic unit (Deodoron), respectively, which both are based on Catator's proprietary wire mesh catalyst technology. The evaluation and the demonstration work have involved laboratory tests with synthetic gases and a number of field tests at plants for biogas production, water and waste treatment. The results show that: 1. In comparison to conventional thermal emission abatement systems, the wire mesh catalyst technology opens up for the construction of very compact (V=0.6 Nm, W=500 kg for 1000 Nm{sup 3}/h) and thermo-economical systems (> 95 %), which technology can easily be scaled up and integrated into existing industrial and/or process streams. 2. Catator's MRO-prototype enables for autothermal oxidation of methane, with a conversion degree of 97-98 %, from an inlet concentration of 0.2 vol% at an operation temperature of 660-700 deg, i.e. 200-300 deg less than when conventional homogenous flame combustion is applied. 3. The performance of the MRO-unit was seen to be somewhat unstable, with an oscillating conversion degree during the operation cycle. This should however be able to overcome by further optimizing the integrated catalyst package and the heat exchanger. Significant improvements in efficiency and stability are also to be expected by the scale-up due to a decreasing heat loss with an increasing capacity 4. Close to 100 % removal of different odorants, with a thermal efficiency of around 80 %, can be obtained by the use of Catator's unit Deodoron at an operation temperature of 300-400 deg. The results were verified by odor tests performed up- and downstream the

  8. Construction, evaluation and demonstration of mobile catalytic combustion units for destruction of methane and different odor pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Jannasch, Anna-Karin [Catator AB, Lund (Sweden)

    2012-02-15

    This project reports on the construction, the evaluation and the demonstration of novel, mobile small-scale (< 100 Nm{sup 3}/h) combustion units for reduction of methane and/or different odour pollutants (e.g. hydrogen sulfide, ammonia, VOC) existing in small concentrations in process air streams. The evaluated units include a regenerative (MeshRegenOx/MRO) and a recuperative, catalytic unit (Deodoron), respectively, which both are based on Catator's proprietary wire mesh catalyst technology. The evaluation and the demonstration work have involved laboratory tests with synthetic gases and a number of field tests at plants for biogas production, water and waste treatment. The results show that: 1. In comparison to conventional thermal emission abatement systems, the wire mesh catalyst technology opens up for the construction of very compact (V=0.6 Nm, W=500 kg for 1000 Nm{sup 3}/h) and thermo-economical systems (> 95 %), which technology can easily be scaled up and integrated into existing industrial and/or process streams. 2. Catator's MRO-prototype enables for autothermal oxidation of methane, with a conversion degree of 97-98 %, from an inlet concentration of 0.2 vol% at an operation temperature of 660-700 deg, i.e. 200-300 deg less than when conventional homogenous flame combustion is applied. 3. The performance of the MRO-unit was seen to be somewhat unstable, with an oscillating conversion degree during the operation cycle. This should however be able to overcome by further optimizing the integrated catalyst package and the heat exchanger. Significant improvements in efficiency and stability are also to be expected by the scale-up due to a decreasing heat loss with an increasing capacity 4. Close to 100 % removal of different odorants, with a thermal efficiency of around 80 %, can be obtained by the use of Catator's unit Deodoron at an operation temperature of 300-400 deg. The results were verified by odor tests performed up- and downstream the

  9. Evaluation of calcium-releasing and apatite-forming abilities of fast-setting calcium silicate-based endodontic materials.

    Science.gov (United States)

    Han, L; Kodama, S; Okiji, T

    2015-02-01

    To evaluate two fast-setting calcium silicate-based endodontic materials (Endocem mineral trioxide aggregate (MTA) and Endocem Zr) with regard to their ability to release calcium ions (Ca(2+)) and produce apatite-like precipitates after immersion in phosphate-buffered saline (PBS). Endocem MTA, Endocem Zr and white ProRoot MTA (WMTA) were used. Chemical composition of the powder of each material was analysed with a wavelength-dispersive X-ray spectroscopy electron probe microanalyser with image observation function (SEM-EPMA). The amount of Ca(2+) released from water-immersed set cements was measured with an EDTA titration method. Morphology and chemical composition of surface precipitates formed on the surface of PBS-immersed cements were analysed with the SEM-EPMA. Data obtained were analysed using one-way analysis of variance and Tukey's honestly significant difference test with a significance level of 5%. Endocem MTA and WMTA contained calcium (Ca), silicon (Si) and bismuth as the major elemental constituents, whereas Endocem Zr contained zirconium as the most abundant element, followed by Ca and Si. The amount of Ca(2+) release was WMTA >Endocem MTA ≥Endocem Zr. After immersion in PBS for 14 days, the three materials produced Ca- and phosphorus (P)-containing apatite-like surface precipitates. WMTA showed higher Ca/P ratio of the precipitates compared with the other cements, with statistical significance between WMTA and Endocem Zr (P < 0.05). Compared with WMTA, Endocem MTA and Endocem Zr were associated with significantly less Ca ions release and, when immersed in PBS, produced apatite-like crystalline precipitates of significantly lower Ca/P ratios. © 2014 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  10. DS926 Digital surfaces and thicknesses of selected hydrogeologic units of the Floridan aquifer system in Florida and parts of Georgia, Alabama, and South Carolina -- Geologic units forming the base of the Floridan aquifer system

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Digital surfaces and thicknesses of selected hydrogeologic units of the Floridan aquifer system were developed to define an updated hydrogeologic framework as part...

  11. DS926 Digital surfaces and thicknesses of selected hydrogeologic units of the Floridan aquifer system in Florida and parts of Georgia, Alabama, and South Carolina -- Geologic units forming the top of the Floridan aquifer system

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Digital surfaces and thicknesses of selected hydrogeologic units of the Floridan aquifer system were developed to define an updated hydrogeologic framework as part...

  12. DS926 Digital surfaces and thicknesses of selected hydrogeologic units of the Floridan aquifer system in Florida and parts of Georgia, Alabama, and South Carolina -- Polygon regions of low-permeability units forming the MAPCU

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Digital surfaces and thicknesses of selected hydrogeologic units of the Floridan aquifer system were developed to define an updated hydrogeologic framework as part...

  13. Evaluation of long-term post-accident core cooling of Three Mile Island Unit 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-04-15

    On the basis of current understanding of the accident scenario and available data, the staff reports here on its evaluation of the condition of the core and the core flow resistance as it might affect ability to cool the core by natural circulation. The natural circulation cooling capability of TMI-2 for the estimated core flow resistance and a variety of other conditions is evaluated and a comparison of the Base Case and off-nominal plant configurations is presented. The potential for and effects of natural convection core cooling are addressed, and the staff recommendations for reactor performance acceptance criteria upon initiation of natural convection are presented.

  14. An evaluation of safety guidelines to restrict exposure to stray radiofrequency radiation from short-wave diathermy units

    Science.gov (United States)

    Shields, Nora; O'Hare, Neil; Gormley, John

    2004-07-01

    Short-wave diathermy (SWD), a form of radiofrequency radiation used therapeutically by physiotherapists, may be applied in continuous (CSWD) or pulsed (PSWD) mode using either capacitive or inductive methods. Stray radiation emitted by these units may exceed exposure guidelines close to the equipment. Discrepant guidelines exist on a safe distance from an operating unit for operators and other personnel. Stray electric (E-field) and magnetic (H-field) field strengths from 10 SWD units in six departments were examined using a PMM 8053 meter and two isotropic probes (EP-330, HP-032). A 5 l saline phantom completed the patient circuit. Measurements were recorded in eight directions between 0.5 m and 2 m at hip and eye levels while the units operated at maximum output and data compared to current guidelines. Results found stray fields from capacitive CSWD fell below operator limits at 2 m (E-field 4.8-39.8 V/m; H-field 0.015-0.072 A/m) and at 1 m for inductive CSWD (E-field 0-36 V/m; H-field 0.01-0.065 A/m). Capacitive PSWD fields fell below the limits at 1.5 m (E-field 1.2-19.9 V/m; H-field 0.002-0.045 A/m) and at 1m for inductive PSWD (E-field 0.7-4.0 V/m; H-field 0.009-0.03 A/m). An extra 0.5 m was required before fields fell below the guidelines for other personnel. These results demonstrate, under a worst case scenario, emissions from SWD exceed the guidelines for operators at distances currently recommended as safe. Future guidelines should include recommendations for personnel other than physiotherapists.

  15. An evaluation of safety guidelines to restrict exposure to stray radiofrequency radiation from short-wave diathermy units

    Energy Technology Data Exchange (ETDEWEB)

    Shields, Nora [School of Physiotherapy, La Trobe University, Victoria 3086 (Australia); O' Hare, Neil [Department of Medical Physics and Bioengineering, St James' s Hospital, Dublin 8 (Ireland); Gormley, John [School of Physiotherapy, Trinity College Dublin, Trinity Centre for Health Sciences, St James' s Hospital, Dublin 8 (Ireland)

    2004-07-07

    Short-wave diathermy (SWD), a form of radiofrequency radiation used therapeutically by physiotherapists, may be applied in continuous (CSWD) or pulsed (PSWD) mode using either capacitive or inductive methods. Stray radiation emitted by these units may exceed exposure guidelines close to the equipment. Discrepant guidelines exist on a safe distance from an operating unit for operators and other personnel. Stray electric (E-field) and magnetic (H-field) field strengths from 10 SWD units in six departments were examined using a PMM 8053 meter and two isotropic probes (EP-330, HP-032). A 5 l saline phantom completed the patient circuit. Measurements were recorded in eight directions between 0.5 m and 2 m at hip and eye levels while the units operated at maximum output and data compared to current guidelines. Results found stray fields from capacitive CSWD fell below operator limits at 2 m (E-field 4.8-39.8 V/m; H-field 0.015-0.072 A/m) and at 1 m for inductive CSWD (E-field 0-36 V/m; H-field 0.01-0.065 A/m). Capacitive PSWD fields fell below the limits at 1.5 m (E-field 1.2-19.9 V/m; H-field 0.002-0.045 A/m) and at 1m for inductive PSWD (E-field 0.7-4.0 V/m; H-field 0.009-0.03 A/m). An extra 0.5 m was required before fields fell below the guidelines for other personnel. These results demonstrate, under a worst case scenario, emissions from SWD exceed the guidelines for operators at distances currently recommended as safe. Future guidelines should include recommendations for personnel other than physiotherapists.

  16. Evaluation of the operational efficiency of pacifying police units in the state of Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Igor Rosa Dias de Jesus

    2014-05-01

    Full Text Available The Pacification Police Unit (UPP is a new model for public security and policing, aimed at ensuring local security and, above all, reduce, or even, extinguish violent crime linked to drug trafficking, and approach people and police. The purpose of this article is measuring the operational efficiency of all UPPs installed in the state of Rio de Janeiro by the beginning of 2011 by Data Envelopment Analysis (DEA. For this, it was used the CCR model – input-oriented – developed by Charnes, Cooper and Rhodes, which allows an objective assessment of the overall efficiency, identifying the sources of inefficiencies and the needed targets to achieve the efficiency in each UPP. The results converge to a reduction of the amount of policemen in all communities out of the efficiency frontier.

  17. EVALUATION OF THE LEARNING SYSTEM BASED ON RESEARCH (SABI IN THE CICS UMA IPN BIOCHEMISTRY UNIT

    Directory of Open Access Journals (Sweden)

    Blanca Elisa Pérez-Magaña

    2014-07-01

    Full Text Available Learning is a steward, permanent, and participatory process where: the apprentice, teacher, classmates, institution and other social factors where the student performs. As detonator of learning is research, which is made from real events that are addressed on the basis of the scientific development of the State of the art. One of the key elements in the professional training of students is the method that is used. Research-based learning system is an educational innovation (SABI, which was used in the learning of basic sciences of the Cardiovascular apparatus in generations unit 33rd, 34th, 35th, 36th and 37th generations in the years of 2008 to 2012's career in medicine and as a result was a decrease in the number of students reproachedimproving achievement. This method is an excellent alternative in the teaching-learning process and can be used both in groups with a variable number of students.

  18. Evaluation of the Contamination Control Unit during simulated transuranic waste retrieval

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, D.N.; Freeman, A.L.; Wixom, V.E.

    1993-11-01

    This report presents the results of a field demonstration at the INEL of the Contamination Control Unit (CCU). The CCU is a field deployable self-contained trailer mounted system to control contamination spread at the site of transuranic (TRU) handling operations. This is accomplished primarily by controlling dust spread. This demonstration was sponsored by the US Department of Energy`s Office of Waste Technology Development Buried Waste Integrated Demonstration. The CCU, housed in a mobile trailer for easy transport, supports four different contamination control systems: water misting, dust suppression application, soil fixative application, and vacuuming operations. Assessment of the CCU involved laboratory operational performance testing, operational testing and contamination control at a decommissioned Idaho National Engineering Laboratory reactor, and field testing in conjunction with a simulated TRU buried waste retrieval effort at the Cold Test Pit.

  19. Development and Evaluation of the Habitat Demonstration Unit Medical Operations Workstation and Opportunities for Future Research

    Science.gov (United States)

    Howard, Robert L., Jr.

    2012-01-01

    As NASA develops missions to leave Earth orbit and explore distant destinations (Mars, Moon, Asteroids) it is necessary to rethink human spaceflight paradigms in the life sciences. Standards developed for low earth orbit human spaceflight may not be fully applicable and in-space research may be required to develop new standards. Preventative and emergency medical care may require new capabilities never before used in space. Due to spacecraft volume limitations, this work area may also be shared with various animal and plant life science research. This paper explores the prototype Medical Operations Workstation within the NASA Habitat Demonstration Unit and discusses some of the lessons learned from field analogue missions involving the workstation. Keywords: Exploration, medical, health, crew, injury emergency, biology, animal, plant, science, preventative, emergency.

  20. Evaluation on Waste Volume and Weight from Decommissioning of Kori Unit 1 Reactor Vessel

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yujeong; Lee, Seong-Cheol; Kim, Chang-Lak [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2015-05-15

    In this paper, the concept of cutting reactor vessel and container for decommissioning Kori unit 1 has been investigated. As a result of the investigation, it is found that cutting the reactor vessel into small pieces, especially for upper and bottom heads of the reactor vessel, is more effective to reduce total disposal volume generated from decommissioning. As a part of continuing efforts to prepare shut down of nuclear power plant, several researches have been conducted to establish plans to dispose decommissioning waste from nuclear power plants. When decommissioning nuclear power plant, most of radioactive waste is generated from primary side including a reactor vessel. Radioactive waste amounts generated from decommissioning is significantly affected by several factors, such as dismantling method, waste classification, reactor lifetime, disposal method and etc.

  1. Evaluation of severe accident risks, Peach Bottom, Unit 2: Main report

    Energy Technology Data Exchange (ETDEWEB)

    Payne, A.C.; Breeding, R.J.; Jow, H.N.; Shiver, A.W. (Sandia National Labs., Albuquerque, NM (USA)); Helton, J.C. (Arizona State Univ., Tempe, AZ (USA)); Smith, L.N. (Science Applications International Corp., Albuquerque, NM (USA))

    1990-12-01

    In support of the Nuclear Regulatory Commission's (NRC's) assessment of the risk from severe accidents at commercial nuclear power plants in the US reported NUREG-1150, the Severe Accident Risk Reduction Program (SARRP) has completed a revised calculation of the risk to the general public from severe accidents at the Peach Bottom Atomic Power Station, Unit 2. This power plant, located in southeastern Pennsylvania, is operated by the Philadelphia Electric Company. The emphasis in this risk analysis was not on determining a so-called'' point estimate of risk. Rather, it was to determine the distribution of risk, and to discover the uncertainties that account for the breadth of this distribution. Off-site risk initiated by events both internal and external to the power station were assessed. 39 refs., 174 figs., 133 tabs.

  2. Evaluating new types of tourniquets by the Israeli Naval special warfare unit.

    Science.gov (United States)

    Heldenberg, Eitan; Aharony, Shahar; Wolf, Tamir; Vishne, Tali

    2015-01-01

    Extremity injuries, which accounts for 20% of all battlefield injuries, result in 7-9% of deaths during military activity. Silicone tourniquets were used, by the Israeli Defense Force (IDF) soldiers, for upper extremity and calf injuries, while thigh injuries were treated by an improvised "Russian" tourniquet (IRT). This is the first study, performed in the IDF, comparing the IRT with Combat Application Tourniquets (CAT) and Special Operations Force Tactical Tourniquets (SOFTT). 23 operators from the Israeli Naval Unit (Shayetet 13) were divided into two groups according to their medical training (11 operators trained as first-responders; 12 operators as medics). Repetitive applications of the three tourniquets over the thigh and upper arm, and self-application of the CAT and SOFTT over the dominant extremity were performed using dry and wet tourniquets (828 individual placements) with efficacy recorded. Cessation of distal arterial flow (palpation; Doppler ultrasound) confirmed success, while failure was considered in the advent of arterial flow or tourniquet instability. Satisfaction questionnaires were filled by the operators. CAT and SOFTT were found to be superior to the IRT, in occluding arterial blood flow to the extremities (22%, 23% and 38%, respectively, failure rate). The application was quicker for the CAT and SOFTT as compared to the IRT (18, 26, 52 seconds, respectively). Wet tourniquets neither prolonged application nor did they increase failure rates. Similarly, medics didn't have any advantage over non-medic operators. No findings indicated superiority of CAT and SOFTT over one another, despite operators' preference of CAT. CAT and SOFTT offer an effective alternative to the IRT in stopping blood flow to extremities. No difference was observed between medics and non-medic operators. Thus, the CAT was elected as the preferred tourniquet by our unit and it is being used by all the operators.

  3. Nutrition and Health with an Evaluation on Nutritional Surveillance in the United States.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Select Committee on Nutrition and Human Needs.

    Focusing on America's self-knowledge about its nutritional health, this report deals with the availability of nutrition evaluation and counseling to individuals and the adequacy of the national nutrition monitoring system. Bureaucratic and political problems of applying nutritional health considerations to food policy are also examined. Nutrition…

  4. Family Planning Evaluation. Abortion Surveillance Report--Legal Abortions, United States, Annual Summary, 1970.

    Science.gov (United States)

    Center for Disease Control (DHEW/PHS), Atlanta, GA.

    This report summarizes abortion information received by the Center for Disease Control from collaborators in state health departments, hospitals, and other pertinent sources. While it is intended primarily for use by the above sources, it may also interest those responsible for family planning evaluation and hospital abortion planning. Information…

  5. The Use of Relative Performance Evaluation at the Business Unit Manager Level

    NARCIS (Netherlands)

    van Elten, Hilco

    2016-01-01

    Relative Performance Evaluation is a widely studies topic in the theoretical and analytical economics and accounting literatures. Also the empirical literature addresses this topic, with its main focus on executive compensation, and using archival data. This study assesses the extent to which RPE is

  6. Using Data Envelopment Analysis to Evaluate Technical Training Program for Maintenance Units

    Directory of Open Access Journals (Sweden)

    Nai-Chieh Wei and Shui-Cheung Cham

    2015-05-01

    Full Text Available Applying data envelope analysis (DEA, this study focuses on the influences of objectivity and subjectivity on aircraft maintenance supervision evaluation and inspection procedure; the aim is to improve overall logistic operation and training efficiency. Moreover, the results of this analysis will be helpful for making decisions in training, management, capability and competitiveness

  7. Evaluation of digital elevation models for delineation of hydrological response units in a Himalayan watershed

    NARCIS (Netherlands)

    Saran, S.; Sterk, G.; Peters, P.D.; Dadhwal, V.K.

    2010-01-01

    This study reports results from evaluation of the quality of digital elevation model (DEM) from four sources viz. topographic map (1: 50,000), Shuttle Radar Topographic Mission (SRTM) (90 m), optical stereo pair from ASTER (15 m) and CARTOSAT (2.5 m) and their use in derivation of hydrological respo

  8. Evaluation of digital elevation models for delineation of hydrological response units in a Himalayan watershed

    NARCIS (Netherlands)

    Saran, S.; Sterk, G.; Peters, P.; Dadhwal, V.K.

    2010-01-01

    This study reports results from evaluation of the quality of digital elevation model (DEM) from four sources viz. topographic map (1:50,000), Shuttle Radar Topographic Mission (SRTM) (90 m), optical stereo pair from ASTER (15 m) and CARTOSAT (2.5 m) and their use in derivation of hydrological respon

  9. An evaluation of marginal fit of three-unit fixed dental prostheses fabricated by direct metal laser sintering system.

    Science.gov (United States)

    Kim, Ki-Baek; Kim, Woong-Chul; Kim, Hae-Young; Kim, Ji-Hwan

    2013-07-01

    This in vitro study aimed to evaluate and compare marginal fit of three-unit fixed dental prostheses (FDPs) fabricated using a newly developed direct metal laser sintering (DMLS) system with that of three-unit FDPs by a conventional lost wax technique (LW) method. Ten cobalt-chromium alloy three-unit FDPs using DMLS system and another ten nickel-chromium alloy FDPs using LW method were fabricated. Marginal fit was examined using a light-body silicone. After setting, the silicon film was cut into four parts and the thickness of silicon layer was measured at 160× magnification using a digital microscope to measure absolute marginal discrepancy (AMD), marginal gap (MG) and internal gap (IG). A repeated measure ANOVA for statistical analysis was performed using the SPSS statistical package version 12.0 (α=0.05). The mean values of AMD, MG, and IG were significantly larger in the DMLS group than in the LW group (p0.05). The marginal fit of the DMLS system appeared significantly inferior compared to that of the conventional LW method and slightly larger than the acceptable range. For clinical application further improvement of DMLS system may be required. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  10. Evaluation of severe accident risks and the potential for risk reduction: Surry Power Station, Unit 1: Draft report for comment

    Energy Technology Data Exchange (ETDEWEB)

    Benjamin, A.S.; Boyd, G.J.; Kunsman, D.M.; Murfin, W.B.; Williams, D.C.

    1987-02-01

    The Severe Accident Risk Reduction Program (SARRP) has completed a rebaselining of the risks to the public from a particular pressurized water reactor with a subatmospheric containment (Surry, Unit 1). Emphasis was placed on determining the magnitude and character of the uncertainties, rather than focusing on a point estimate. The risk-reduction potential of a set of proposed safety option backfits was also studied, and their costs and benefits were also evaluated. It was found that the risks from internal events are generally lower than previously evaluated in the Reactor Safety Study (RSS). However, certain unresolved issues (such as direct containment heating) caused the top of the uncertainty band to appear at a level that is comparable with the RSS point estimate. None of the postulated safety options appears to be cost effective for the Surry power plant. This work supports the Nuclear Regulatory Commission's assessment of severe accidents in NUREG-1150.

  11. Critical evaluation of the nonradiological environmental technical specifications. Volume 4. San Onofre Nuclear Generating Station, Unit 1

    Energy Technology Data Exchange (ETDEWEB)

    Adams, S.M.; Cunningham, P.A.; Gray, D.D.; Kumar, K.D.

    1976-08-10

    A comprehensive study of the data collected as part of the environmental Technical Specifications program for Unit 1 of the San Onofre Nuclear Generating Station (SONGS 1) was conducted for the Office of Nuclear Regulatory Research of the U.S. Nuclear Regulatory Commission. The program included an analysis of the hydrothermal and ecological monitoring data collected during 1975. The hydrothermal analysis includes a discussion of models used in plume predictions prior to plant operation and an evaluation of the present hydrothermal monitoring program. The ecological evaluation was directed toward reviewing the strengths and weaknesses of the various sampling programs designed to monitor the planktonic, benthic, and nektonic communities inhabiting the inshore coastal area in the vicinity of San Onofre.

  12. [Two years of legal practice of euthanasia in Belgium: comparison with the Netherlands. First evaluation in a palliative care unit].

    Science.gov (United States)

    Englert, M; Hanson, B; Lossignol, D

    2005-01-01

    The Belgian law relative to euthanasia prescribes that a physician performing an euthanasia has to complete a registration document and to send it within 4 days to the federal commission for control and evaluation of euthanasia. The 259 first documents are described in the report of the commission referred to Parliament on September 17, 2004. The present paper analyses this report and compares its most important data with those published in the Netherlands: apart from the total number of euthanasia's, much smaller in Belgium, and apart from aspects which are specifically related to the Belgian law, the statistical data are very similar in both countries. The difference in the number of registration documents written in French and in Flemish is analyzed and discussed. A first evaluation of the application of the law in a supportive and palliative care unit is reported.

  13. Evaluation and Screening of Remedial Technologies for Uranium at the 300-FF-5 Operable Unit, Hanford Site, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Nimmons, Michael J.

    2007-08-01

    Pacific Northwest National Laboratory (PNNL) is presently conducting a re-evaluation of remedies addressing persistent dissolved uranium concentrations in the upper aquifer under the 300 Area of the Hanford Site in southeastern Washington State. This work is being conducted as a Phase III feasibility study for the 300-FF-5 Operable Unit on behalf of the U.S. Department of Energy. As part of the feasibility study process, a comprehensive inventory of candidate remedial technologies was conducted by PNNL. This report documents the identification and screening of candidate technologies. The screening evaluation was conducted in accordance with guidance and processes specified by U.S. Environmental Protection Agency regulations associated with implementation of the Comprehensive Environmental Response, Compensation, and Liability Act process.

  14. Evaluation of the shielding of dental X-rays units; Evaluacion del blindaje de unidades de rayos X dentales

    Energy Technology Data Exchange (ETDEWEB)

    Medrano, E.; Vega C, H. R.; Letechipia de L, C.; Hernandez D, V. M.; Salas L, M. A., E-mail: edumeco@yahoo.com.mx [Universidad Autonoma de Zacatecas, Apdo. Postal 336, 98000 Zacatecas (Mexico)

    2014-08-15

    The capacity of the walls of the dental radio-diagnostic rooms has been determined, to diminish the dose levels during the use of the X-rays equipment s. The study was carried out in the Dentistry Academic Unit of the campus Siglo X XI of the Universidad Autonoma de Zacatecas. The X-rays equipment s are a learning tool for the dentistry students and they are also used for offering health services to the population; for this reason is important to verify that the dose levels outside of the room walls are safe. During the evaluation process were used conservative approaches without prejudice of the thickness necessary in benefit of the radiological protection. Of the evaluation was found that all the walls satisfy their function thoroughly like barriers against the X-rays. (Author)

  15. Simplified methods for the evaluation of the risk of forming renal stones and the follow-up of stone-forming propensity during the preventive treatment of stone-formation.

    Science.gov (United States)

    Grases, Fèlix; Costa-Bauzá, Antonia

    2016-02-01

    Renal lithiasis is a complex multifactorial disease in which recurrence is common. Thus, simple and reliable procedures are needed to evaluate patients with previous kidney stones to determine the risk of recurrence. In this paper we review simple biochemical procedures that can be used to determine the risk for renal stone formation when the stone is available or unavailable for analysis. Our present knowledge of renal lithiasis indicates that renal stones form due to several well-defined factors. Analysis of the renal stone itself can provide important information about clinical factors that require further investigation. When the stone is unavailable, it is necessary to perform a general evaluation of main urinary risk factors associated to renal stone formation, but this study should be complemented considering information related to direct familial antecedents, recidivant degree, radiological images, medical history, and life style habits. Finally, tools for patient follow-up of stone-forming propensity during the preventive treatment are discussed .

  16. Sizing personnel: evaluation of nursing in obstetric and mixed pediatric intensive care units

    OpenAIRE

    Mendes,Rodrigo Nonato Coelho; Carmo, Amanda de Figueirôa Silva; Salum, Rosana Dourado Loula; Gusmão-filho,Fernando Antônio Ribeiro de; Vidal, Suely Arruda; Santos, Viviane Euzébia Perreira

    2013-01-01

    Objectives: To assess the adequacy of nursing staff and understand how these professionals perceive this issue. Methods: evaluative, exploratory, descriptive, quantitative and qualitative study, developed in Obstetric and Mixed Pediatric ICUs for the Hospital Don Malan / IMIP in Petrolina-PE. Was calculated the scaling nursing and 13 semistructured interviews were conducted, analyzed according to Bardin. Results: Mixed Pediatric ICU has correct number of staff and Obstetric decrea...

  17. Flattening filter free beams from TrueBeam and Versa HD units: Evaluation of the parameters for quality assurance

    Energy Technology Data Exchange (ETDEWEB)

    Fogliata, Antonella, E-mail: antonella.fogliata@humanitas.it; Reggiori, Giacomo; Stravato, Antonella; Scorsetti, Marta; Cozzi, Luca [Radiotherapy and Radiosurgery Department, Humanitas Research Hospital, Milan-Rozzano I-20098 (Italy); Fleckenstein, Jens; Schneider, Frank; Lohr, Frank [Department of Radiation Oncology, University Medical Center Mannheim, University of Heidelberg, Mannheim D-68167 (Germany); Pachoud, Marc; Ghandour, Sarah [Radiation Oncology Department, Hôpital Riviera Chablais, Vevey CH-1800 (Switzerland); Krauss, Harald [Radio-Oncology Department, Kaiser Franz Josef Spital, Vienna A-1100 (Austria)

    2016-01-15

    Purpose: Flattening filter free (FFF) beams generated by medical linear accelerators are today clinically used for stereotactical and non-stereotactical radiotherapy treatments. Such beams differ from the standard flattened beams (FF) in the high dose rate and the profile shape peaked on the beam central axis. Definition of new parameters as unflatness and slope for FFF beams has been proposed based on a renormalization factor for FFF profiles. The present study aims to assess the dosimetric differences between FFF beams generated by linear accelerators from different vendors, and to provide renormalization and parameter data of the two kinds of units. Methods: Dosimetric data from two Varian TrueBeam and two Elekta Versa HD linear accelerators, all with 6 and 10 MV nominal accelerating potentials, FF and FFF modes have been collected. Renormalization factors and related fit parameters according to Fogliata et al. [“Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy,” Med. Phys. 39, 6455–6464 (2012)] have been evaluated for FFF beams of both units and energies. Unflatness and slope parameters from profile curves were evaluated. Dosimetric differences in terms of beam penetration and near-the-surface dose were also assessed. Results: FFF profile parameters have been updated; renormalization factors and unflatness from the Varian units are consistent with the published data. Elekta FFF beam qualities, different from the Varian generated beams, tend to express similar behaviour as the FF beam of the corresponding nominal energy. TPR{sub 20,10} for 6 and 10 MV FF and FFF TrueBeam beams are 0.665, 0.629 (6 MV) and 0.738, 0.703 (10 MV). The same figures for Versa HD units are 0.684, 0.678 (6 MV) and 0.734, 0.721 (10 MV). Conclusions: Renormalization factor and unflatness parameters evaluated from Varian and Elekta FFF beams are provided, in particular renormalization factors table and fit parameters.

  18. Evaluation and targeting of geothermal energy resources in the southeastern United States. Progress report, May 1, 1976--October 31, 1976

    Energy Technology Data Exchange (ETDEWEB)

    Costain, J.K.; Glover, L. III; Sinha, A.K.

    1976-01-01

    Progress is reported in the development of procedures for the evaluation of low-temperature radiogenically-derived geothermal resources in the eastern United States utilizing geological geochemical, and geophysical data. An optimum site for geothermal development in the tectonically stable eastern United States will probably be associated with crustal igneous rocks containing relatively high concentrations of radiogenic heat-producing elements buried beneath an insulating blanket of sediments of low thermal conductivity. Evaluation of plutonic rocks exposed in the Piedmont will aid in the interpretation of gravity and magnetic data for the Atlantic Coastal Plain. Initial results of determination of heat generation from surface samples in South Caroline are encouraging, especially if granitic igneous rocks of similar heat generation can be found beneath sedimentary insulation. Continues logging of existing wells in Coastal Plain sediments supports earlier conclusion that these sediments do behave as efficient sedimentary insulators. Higher temperatures appear to be reached at shallower depths for wells drilled in Coastal Plain sediments in the vicinity of the Georgetown, South Carolina gravity law. Detailed structural mapping in the vicinity of the warm springs in northwestern Virginia has confirmed structural control of the warm springs, and has revealed the existence of kink bands. The kink bands could be related to the development of zones of vertical permeability which serve as conduits in sedimentary rocks for ascending hot water.

  19. Data envelopment analysis model for the appraisal and relative performance evaluation of nurses at an intensive care unit.

    Science.gov (United States)

    Osman, Ibrahim H; Berbary, Lynn N; Sidani, Yusuf; Al-Ayoubi, Baydaa; Emrouznejad, Ali

    2011-10-01

    The appraisal and relative performance evaluation of nurses are very important and beneficial for both nurses and employers in an era of clinical governance, increased accountability and high standards of health care services. They enhance and consolidate the knowledge and practical skills of nurses by identification of training and career development plans as well as improvement in health care quality services, increase in job satisfaction and use of cost-effective resources. In this paper, a data envelopment analysis (DEA) model is proposed for the appraisal and relative performance evaluation of nurses. The model is validated on thirty-two nurses working at an Intensive Care Unit (ICU) at one of the most recognized hospitals in Lebanon. The DEA was able to classify nurses into efficient and inefficient ones. The set of efficient nurses was used to establish an internal best practice benchmark to project career development plans for improving the performance of other inefficient nurses. The DEA result confirmed the ranking of some nurses and highlighted injustice in other cases that were produced by the currently practiced appraisal system. Further, the DEA model is shown to be an effective talent management and motivational tool as it can provide clear managerial plans related to promoting, training and development activities from the perspective of nurses, hence increasing their satisfaction, motivation and acceptance of appraisal results. Due to such features, the model is currently being considered for implementation at ICU. Finally, the ratio of the number DEA units to the number of input/output measures is revisited with new suggested values on its upper and lower limits depending on the type of DEA models and the desired number of efficient units from a managerial perspective.

  20. An operational evaluation of the Community Oral Rehydration Units in Peru.

    Science.gov (United States)

    Benavides, B M; Jacoby, E R

    1994-12-01

    Since 1984, in Latin America donor agencies and national governments have extensively supported the implementation of the Community Oral Rehydration Units (CORUs) in an attempt to increase the access to oral rehydration therapy and improve the case management of diarrhoea at the community level. This study surveyed 40 CORUs in two regions of Peru to assess their operation, the number of patients with diarrhoea attended, and the knowledge of volunteers in charge. The results show that CORUs were mainly implemented close to existing health centres; the median of case load was 2.0 patients in the preceding month; and the volunteers' knowledge of case management was principally deficient in the diagnosis of hydration status, dietary management and in preventive measures. This lack of knowledge was replicated by professionals at the supervising health centres. Despite the fact that CORUs have been functioning for around four years, they exhibit numerous deficiencies which prevent them from fulfilling their objectives. A global review of the whole CORU strategy is called for.

  1. Interstitial cystitis/painful bladder syndrome: diagnostic evaluation and therapeutic response in a private urogynecology unit

    Science.gov (United States)

    González-Ruiz, Maria Isabel; Martínez-Espinoza, Claudia J.; Monroy-Rodríguez, Fabiola; Zaragoza-Torres, Rocio M.

    2015-01-01

    Background Interstitial cystitis/painful bladder syndrome (IC/PBS) is a spectrum of pelvic, bladder or urethral pain, as well as irritative voiding symptoms. The term interstitial cystitis (IC) is reserved for patients with typical cystoscopic features. Diagnosis and management of this syndrome may be difficult. The aim of this study was to describe endoscopic features and our experience on the treatment of this syndrome in Urodifem de Occidente S.C., a private urogynecology unit. Methods Observational, retrospective analytic study of 25 treated patients from 33 with diagnosis of IC/PBS between January 2001 and March 2015. The diagnosis was done by clinical, cystoscopic and urodynamic approach. Treatment was based on bladder instillation of dymetilsulfoxido (DMSO), dexamethasone and heparin. Oral pentosan polysulphate was prescribed for at least 1 year. Results Cystoscopic findings showed petechial hemorrhages in 32%, Hunner’s lesions in 28%, glomerulations in 28% and bladder pain in absence of lesions in 12%. The basic treatment included one instillation once a week for 6 weeks, twice a month for 2 months and four monthly instillations. Three cases had complete remission of their symptoms, 21 had significant improvement and we have only one failure. Conclusions We recommend the combined use of DMSO instillation and pentosan polysulphate (PPS) in cases of IC/PBS. PMID:26816862

  2. Evaluating Potential Changes in Fire Risk from Eucalyptus Plantings in the Southern United States

    Directory of Open Access Journals (Sweden)

    Scott L. Goodrick

    2012-01-01

    Full Text Available Renewed interest in short-rotation woody crops for bioenergy and bioproducts has prompted a reevaluation of the Eucalyptus species for the southern United States. One question that arises about the potential effects of introducing a nonnative species is what effect will there be on fire behavior. Our approximate answer based on modeling fire behavior using the Fuel Characteristic Classification System is that surface fire behavior in young stands differs little from surface fires common to pine plantations in the southern Coastal Plain. By the age of 9, the absence of a shrub layer, along with an increased height to live crown, reduced initiation potential despite increased bark shedding. When a shrub layer was introduced in the model, the initiation potential became equivalent to common Pinus fuelbeds. If a crown is ignited, however, the potentials for transmissivity and spread are very high, and the potential for crown fire behavior is more severe. Our modeling effort suggests that fire behavior at the stand level differs little from current conditions and points to the importance of avoiding the development of a shrub layer. Stands managed on short rotation (less than 10 years will likely be harvested before bark shedding presents a significant spotting problem.

  3. Evaluation of a validated food frequency questionnaire for self-defined vegans in the United States.

    Science.gov (United States)

    Dyett, Patricia; Rajaram, Sujatha; Haddad, Ella H; Sabate, Joan

    2014-07-08

    This study aimed to develop and validate a de novo food frequency questionnaire for self-defined vegans in the United States. Diet histories from pilot samples of vegans and a modified 'Block Method' using seven selected nutrients of concern in vegan diet patterns, were employed to generate the questionnaire food list. Food frequency responses of 100 vegans from 19 different U.S. states were obtained via completed mailed questionnaires and compared to multiple telephone-conducted diet recall interviews. Computerized diet analyses were performed. Correlation coefficients, t-tests, rank, cross-tabulations, and probability tests were used to validate and compare intake estimates and dietary reference intake (DRI) assessment trends between the two methods. A 369-item vegan-specific questionnaire was developed with 252 listed food frequency items. Calorie-adjusted correlation coefficients ranged from r = 0.374 to 0.600 (p vegans). This vegan-specific questionnaire can be a useful assessment tool for health screening initiatives in U.S. vegan communities.

  4. The United States does a poor job of evaluating Medicare hospitals: perhaps Australia can help.

    Science.gov (United States)

    Bogart, G

    1992-01-01

    The United States spends more money per person on healthcare than does any other country in the world, and this rate of spending is increasing. Healthcare expenses currently absorb more than 12 percent of the American gross national product, and recent projections indicate that such expenses will exceed 16 percent by the year 2000. By the year 2005, the U.S. Medicare program is expected to absorb more of the national budget than either Social Security or defense. One justification for the high rate of spending has been that, for those who receive it, U.S. healthcare is the best in the world. There is, however, no way to validate this view because no national or international agreed-upon set of criteria for measuring quality of care exists. Proponents of the American system seem to assume that if it costs more, it must be better. If this is true, it is certainly not reflected in American consumer satisfaction: a recent poll of citizens of ten developed countries indicated that Americans were by far the least satisfied with their healthcare system. This article focuses on the American oversight of Medicare hospitals to determine it, in this narrow area, dissatisfied American consumers are justified.

  5. Evaluation of a Validated Food Frequency Questionnaire for Self-Defined Vegans in the United States

    Science.gov (United States)

    Dyett, Patricia; Rajaram, Sujatha; Haddad, Ella H.; Sabate, Joan

    2014-01-01

    This study aimed to develop and validate a de novo food frequency questionnaire for self-defined vegans in the United States. Diet histories from pilot samples of vegans and a modified ‘Block Method’ using seven selected nutrients of concern in vegan diet patterns, were employed to generate the questionnaire food list. Food frequency responses of 100 vegans from 19 different U.S. states were obtained via completed mailed questionnaires and compared to multiple telephone-conducted diet recall interviews. Computerized diet analyses were performed. Correlation coefficients, t-tests, rank, cross-tabulations, and probability tests were used to validate and compare intake estimates and dietary reference intake (DRI) assessment trends between the two methods. A 369-item vegan-specific questionnaire was developed with 252 listed food frequency items. Calorie-adjusted correlation coefficients ranged from r = 0.374 to 0.600 (p vegans). This vegan-specific questionnaire can be a useful assessment tool for health screening initiatives in U.S. vegan communities. PMID:25006856

  6. Evaluation of a Validated Food Frequency Questionnaire for Self-Defined Vegans in the United States

    Directory of Open Access Journals (Sweden)

    Patricia Dyett

    2014-07-01

    Full Text Available This study aimed to develop and validate a de novo food frequency questionnaire for self-defined vegans in the United States. Diet histories from pilot samples of vegans and a modified ‘Block Method’ using seven selected nutrients of concern in vegan diet patterns, were employed to generate the questionnaire food list. Food frequency responses of 100 vegans from 19 different U.S. states were obtained via completed mailed questionnaires and compared to multiple telephone-conducted diet recall interviews. Computerized diet analyses were performed. Correlation coefficients, t-tests, rank, cross-tabulations, and probability tests were used to validate and compare intake estimates and dietary reference intake (DRI assessment trends between the two methods. A 369-item vegan-specific questionnaire was developed with 252 listed food frequency items. Calorie-adjusted correlation coefficients ranged from r = 0.374 to 0.600 (p < 0.001 for all analyzed nutrients except calcium. Estimates, ranks, trends and higher-level participant percentile placements for Vitamin B12 were similar with both methods. Questionnaire intakes were higher than recalls for most other nutrients. Both methods demonstrated similar trends in DRI adequacy assessment (e.g., significantly inadequate vitamin D intake among vegans. This vegan-specific questionnaire can be a useful assessment tool for health screening initiatives in U.S. vegan communities.

  7. Collaborative form(s)

    DEFF Research Database (Denmark)

    Gunn, Wendy

    Gunn asks us to consider beauty as collaborative forms of action generated by moving between design by means of anthropology and anthropology by means of design. Specifically, she gives focus to play-like reflexions on practices of designing energy products, systems and infrastructure. Design...

  8. Development and evaluation of gastroretentive raft forming systems incorporating curcumin-Eudragit® EPO solid dispersions for gastric ulcer treatment.

    Science.gov (United States)

    Kerdsakundee, Nattha; Mahattanadul, Sirima; Wiwattanapatapee, Ruedeekorn

    2015-08-01

    Novel raft forming systems incorporating curcumin-Eudragit® EPO solid dispersions were developed to prolong the gastric residence time and provide for a controlled release therapy of curcumin to treat gastric ulcers. The solid dispersions of curcumin with Eudragit® EPO were prepared by the solvent evaporation method at various ratios to improve the solubility and the dissolution of curcumin. The optimum weight ratio of 1:5 for curcumin to Eudragit® EPO was used to incorporate into the raft forming systems. The raft forming formulations were composed of curcumin-Eudragit® EPO solid dispersions, sodium alginate as a gelling polymer and calcium carbonate for generating divalent Ca(2+) ions and carbon dioxide to form a floating raft. All formulations formed a gelled raft in 1min and sustained buoyancy on the 0.1N hydrochloric acid (pH 1.2) surface with a 60-85% release of curcumin within 8h. The curative effect on the acetic acid-induced chronic gastric ulcer in rats was determined. The curcumin raft forming formulations at 40mg/kg once daily showed a superior curative effect on the gastric ulcer in terms of the ulcer index and healing index than the standard antisecretory agent: lansoprazole (1mg/kg, twice daily) and a curcumin suspension (40mg/kg, twice daily). These studies demonstrated that the new raft forming systems containing curcumin solid dispersions are promising carriers for a stomach-specific delivery of poorly soluble lipophilic compounds.

  9. Evaluating United States and world consumption of neodymium, dysprosium, terbium, and praseodymium in final products

    Science.gov (United States)

    Hart, Matthew

    This paper develops scenarios of future rare-earth-magnet metal (neodymium, dysprosium, terbium, and praseodymium) consumption in the permanent magnets used in wind turbines and hybrid electric vehicles. The scenarios start with naive base-case scenarios for growth in wind-turbine and hybrid-electric-vehicle sales over the period 2011 to 2020, using historical data for each good. These naive scenarios assume that future growth follows time trends in historical data and does not depend on any exogenous variable. Specifically, growth of each technological market follows historical time trends, and the amount of rare earths used per unit of technology remains fixed. The chosen reference year is 2010. Implied consumptions of the rare earth magnet metals are calculated from these scenarios. Assumptions are made for the material composition of permanent magnets, the market share of permanent-magnet wind turbines and vehicles, and magnet weight per unit of technology. Different scenarios estimate how changes in factors like the material composition of magnets, growth of the economy, and the price of a substitute could affect future consumption. Each scenario presents a different method for reducing rare earth consumption and could be interpreted as potential policy choices. In 2010, the consumption (metric tons, rare-earth-oxide equivalent) of each rare-earth-magnet metal was as follows. Total neodymium consumption in the world for both technologies was 995 tons; dysprosium consumption was 133 tons; terbium consumption was 50 tons; praseodymium consumption was zero tons. The base scenario for wind turbines shows there could be strong, exponential growth in the global wind turbine market. New U.S. sales of hybrid vehicles would decline (in line with the current economic recession) while non-U.S. sales increase through 2020. There would be an overall increase in the total amount of magnetic rare earths consumed in the world. Total consumption of each rare earth in the short

  10. Development and Evaluation of High-Resolution Climate Simulations Over the Mountainous Northeastern United States

    Science.gov (United States)

    Winter, Jonathan M.; Beckage, Brian; Bucini, Gabriela; Horton, Radley M.; Clemins, Patrick J.

    2016-01-01

    The mountain regions of the northeastern United States are a critical socioeconomic resource for Vermont, New York State, New Hampshire, Maine, and southern Quebec. While global climate models (GCMs) are important tools for climate change risk assessment at regional scales, even the increased spatial resolution of statistically downscaled GCMs (commonly approximately 1/ 8 deg) is not sufficient for hydrologic, ecologic, and land-use modeling of small watersheds within the mountainous Northeast. To address this limitation, an ensemble of topographically downscaled, high-resolution (30"), daily 2-m maximum air temperature; 2-m minimum air temperature; and precipitation simulations are developed for the mountainous Northeast by applying an additional level of downscaling to intermediately downscaled (1/ 8 deg) data using high-resolution topography and station observations. First, observed relationships between 2-m air temperature and elevation and between precipitation and elevation are derived. Then, these relationships are combined with spatial interpolation to enhance the resolution of intermediately downscaled GCM simulations. The resulting topographically downscaled dataset is analyzed for its ability to reproduce station observations. Topographic downscaling adds value to intermediately downscaled maximum and minimum 2-m air temperature at high-elevation stations, as well as moderately improves domain-averaged maximum and minimum 2-m air temperature. Topographic downscaling also improves mean precipitation but not daily probability distributions of precipitation. Overall, the utility of topographic downscaling is dependent on the initial bias of the intermediately downscaled product and the magnitude of the elevation adjustment. As the initial bias or elevation adjustment increases, more value is added to the topographically downscaled product.

  11. Evaluation of indoor environmental quality conditions in elementary schools׳ classrooms in the United Arab Emirates

    Directory of Open Access Journals (Sweden)

    Moshood Olawale Fadeyi

    2014-06-01

    Full Text Available This study presents findings of indoor environmental quality (IEQ investigations conducted in elementary schools׳ classrooms in the United Arab Emirates (UAE. Average TVOC, CO2, O3, CO, and particle concentrations measured in the classrooms were 815 µg/m3, 1605 ppm, 0.05 ppm, 1.16 ppm, and 1730 µg/m3, respectively. Whereas, local authority known as Dubai Municipality recommended 300 µg/m3, 800 ppm, 0.06 ppm, 9 ppm, and 150–300 µg/m3 for TVOC, CO2, O3, CO, and particle, respectively. Dubai Municipality recommended temperature and relative humidity (RH levels of 22.5 °C to 25.5 °C and 30%–60%, respectively. Average temperature and RH levels measured in the classrooms were 24.5 °C and 40.4%, respectively. Average sound level in the classrooms was 24 dB greater than recommended sound level limit of 35 dB. Six (6 classrooms had average lux levels in the range of 400–800 lux. Two (2 classrooms had average lux levels in the range of 100–200 lux. The remaining classrooms had lux levels around the recommended 300 lux. High occupancy density was observed in majority of the studied classrooms. Observations during walkthrough investigations could be used to explain measured IEQ data. Poor IEQ conditions in the studied classrooms highlight the need for further research investigation to understand how poor classrooms׳ IEQ condition could influence students׳ health, comfort, attendance rate, and academic performance.

  12. The evaluation of cases with pneumothorax in the neonatal intensive care unit

    Directory of Open Access Journals (Sweden)

    Müsemma Karabel

    2013-09-01

    Full Text Available Objectives: Early diagnosis and treatment is essentialin reducing mortality in newborns with pneumothorax. Inthis study, newborns with a diagnosis of pneumothorax inneonatal intensive care unit of our hospital were evaluatedand aimed to increase the awareness of physicians.Methods: 12 cases with pneumothorax were evaluatedretrospectively. The gender, birth weight, gestational age,mode of delivery, the presence of underlying disease,pneumothorax localization, implementation of the surfactantand mechanical ventilation and existence or absenceof mortality were recorded.Results: During the study, pneumothorax was detected12 patients. Male/female ratio was 1.4. Eight of the patientshad born with cesarean delivery, the mean birthweight of cases was 2623±912 g and, 66.7% of caseswere term babies. Pneumothorax was observed in thefirst week of life in all patients and it occurred spontaneouslyin 4 patients. The frequency of bilateral pneumothoraxwas 41.7%. For the treatment, closed tube drainagewas performed in 9 patients. The overall mortality ratewas 66.7%. Half of the patients who died had congenitalanomalies such as diaphragmatic eventration (n=1,hydrocephalus (n=1, encephalocel (n=1, non-immunehydrops fetalis (n=1.Conclusion: Additional congenital anomalies, such asPDAs and persistent pulmonary hypertension were foundto be effective on mortality in neonates with pneumothorax.Although, it is a life-threatening condition, the emergencytreatment is life saving. Therefore, in patients withrisk factors, keeping pneumothorax in mind is also thefirst step of the treatment. J Clin Exp Invest 2013; 4 (3:289-292Key words: Newborn, respiratuar distress, pneumothorax,treatment, outcome

  13. Evaluating drought in the United States using the emissivity difference vegetation index

    Science.gov (United States)

    Hirani, Hanisha K.

    As monitoring vegetation and crops becomes increasingly important due to climate change, there arises the need for a monitoring scheme that places more weight on water availability as an indication of vegetation health and vitality. The Emissivity Difference Vegetation Index (EDVI) is the first step towards that type of monitoring scheme. With the potential for diurnal studies, there are applications towards agriculture monitoring, wildfire monitoring, and much more. EDVI is a synergetic product retrieved from microwave, visible, and infrared satellite measurements, as well as reanalysis. Since microwave measurements are more sensitive to vegetation water content, EDVI has the potential to capture intrinsic changes in vegetation. A new drought index is developed from EDVI, the Emissivity Vegetation Condition Index (EVCI). The high temporal sampling of EVCI will make it one of the more dynamic attempts to measure and investigate drought impacts on vegetation and crops on short-term scales. This new drought index will be compared to presently operational drought indices including the Palmer drought indices, the Vegetation Condition Index (VCI), and the Vegetation Health Index (VHI) for the period between 2009-2011 in the United States. The focus will be on improving the methodology of the EDVI retrieval and then examining two periods of identified drought, one in the Southern Great Plains in 2011, and one short-term drought in the Great Lakes region in 2010. The results indicate an agreement between ECVI and precipitation, and the drought episodes in 2010 and 2011 are resolved by EVCI. With a dataset beyond the three years used for this study it would be possible to correct more accurately for climatology.

  14. Systematic Evaluation of Industrial, Commercial, and Institutional Food Waste Management Strategies in the United States.

    Science.gov (United States)

    Hodge, Keith L; Levis, James W; DeCarolis, Joseph F; Barlaz, Morton A

    2016-08-16

    New regulations and targets limiting the disposal of food waste have been recently enacted in numerous jurisdictions. This analysis evaluated selected environmental implications of food waste management policies using life-cycle assessment. Scenarios were developed to evaluate management alternatives applicable to the waste discarded at facilities where food waste is a large component of the waste (e.g., restaurants, grocery stores, and food processors). Options considered include anaerobic digestion (AD), aerobic composting, waste-to-energy combustion (WTE), and landfilling, and multiple performance levels were considered for each option. The global warming impact ranged from approximately -350 to -45 kg CO2e Mg(-1) of waste for scenarios using AD, -190 to 62 kg CO2e Mg(-1) for those using composting, -350 to -28 kg CO2e Mg(-1) when all waste was managed by WTE, and -260 to 260 kg CO2e Mg(-1) when all waste was landfilled. Landfill diversion was found to reduce emissions, and diverting food waste from WTE generally increased emissions. The analysis further found that when a 20 year GWP was used instead of a 100 year GWP, every scenario including WTE was preferable to every scenario including landfill. Jurisdictions seeking to enact food waste disposal regulations should consider regional factors and material properties before duplicating existing statutes.

  15. [Evaluation of the Internet presence of diagnostic radiology units at German universities].

    Science.gov (United States)

    Seitz, J; Siegmund, M; Völk, M; Feuerbach, S; Strotzer, M

    2002-09-01

    Analyzing the availability and the contents of the internet homepages of the radiological departments of German universities. In June and July 2001 the internet homepages of 36 radiological departments of German universities were evaluated in a study. A medical student experienced in using the world wide web examined the websites concerning the following criteria: research, teaching, informations for patients, clinical topics and general information. Additionally an evaluation of the technical standard of the presentation was performed. 31 of the 36 radiological departments presented a homepage in the world wide web. The subject research was presented by 29 institutes. Also 29 departments provided information concerning teaching in their presentations. In 24 cases informations especially for patients were given. In all topics there is a huge variety of the quality and quantity of the provided information throughout the different institutions. 21 homepages available without restriction during the study period; 3 were nearly completely under construction. Multimedia techniques were only used in 2 homepages. The structural hierarchy of the webpages was in the average only two or three levels. Only 6 providers presented an additional version of their homepage in english. In the moment the possibility of internet-presentation is sub-optimal used by the responsible persons of the radiological institutions. The main emphasis is on research and teaching. There is nearly no use of multimedial elements in the presentations. Only a minority of the homepages can be read by international viewers because of the lack of an english version of the pages.

  16. "Evaluation of Risk Factors Causing Musculoskeletal Disorders Using QEC Method in a Furniture Producing Unite"

    Directory of Open Access Journals (Sweden)

    M Mirmohamadi

    2004-07-01

    Full Text Available The musculoskeletal disorders cover a large percent of occupational diseases; therefore, in order to protect workers from such disorders, there is a need to evaluate workers positions at work in different industries. In a major furniture manufacture located in Tehran, 500 workers were examined. These workers were divided into fourteen working groups, including production lines of water-heater, air condition, electromotor production line, dunnage making hall, plastic hall, smithery, restaurant, store, engineers and supervisors, facilities, transportation, assembly of absorptive refrigerator and drivers. The results from Nordic Questionnaire and performing the evaluation method showed that, there was a significant relevance between outbreak of back pain and workgroups (P=0.005 and between the outbreak of pain in neck and workgroup as well. A significant relevance of P=0.005 indicating that, the working in the above mentioned work-place causes pain in both back and neck. Between other parts of the body and workgroup no significant relevance observed. Among workgroups, there was a significant relevance between the water-heater production line (P<0.005 and pain in the back, and there was also a significant relevance among the work in air–conditioning production line and the plastic injection (P=0.002, causing pain in the neck. The results from Quick Exposure Check (QEC in one hundred working posture have shown that 10% of them fall into first and second level and 90% of them were categorized in third and forth levels.

  17. Evaluation of the London Measure of Unplanned Pregnancy in a United States population of women.

    Directory of Open Access Journals (Sweden)

    Diane Morof

    Full Text Available OBJECTIVE: To evaluate the reliability and validity of the London Measure of Unplanned Pregnancy (a U.K.-developed measure of pregnancy intention, in English and Spanish translation, in a U.S. population of women. METHODS: A psychometric evaluation study of the London Measure of Unplanned Pregnancy (LMUP, a six-item, self-completion paper measure was conducted with 346 women aged 15-45 who presented to San Francisco General Hospital for termination of pregnancy or antenatal care. Analyses of the two language versions were carried out separately. Reliability (internal consistency was assessed using Cronbach's alpha and item-total correlations. Test-retest reliability (stability was assessed using weighted Kappa. Construct validity was assessed using principal components analysis and hypothesis testing. RESULTS: Psychometric testing demonstrated that the LMUP was reliable and valid in both U.S. English (alpha = 0.78, all item-total correlations >0.20, weighted Kappa = 0.72, unidimensionality confirmed, hypotheses met and Spanish translation (alpha = 0.84, all item-total correlations >0.20, weighted Kappa = 0.77, unidimensionality confirmed, hypotheses met. CONCLUSION: The LMUP was reliable and valid in U.S. English and Spanish translation and therefore may now be used with U.S. women.

  18. Multi-compartmental transdermal patch for simultaneous delivery of multiple drugs:formulation and evaluation of newly developed novel dosage form

    Institute of Scientific and Technical Information of China (English)

    Vijayan Venugopal; Jayaraja Kumar; Selvadurai Muralidharan; P. Vasanth Raj

    2015-01-01

    Objective: To evaluate the formulation of multi-compartmental transdermal patches for simultaneous delivery of multiple drugs: aceclofenac and serratiopeptidase. Methods: The patch was prepared by simple solvent casting method using hydroxy propyl methyl celluloseK100Mas matrix forming agent and dimethyl sulphoxide as permeation enhancer. The prepared transdermal patch was evaluated by physiochemical parameters andin-vitro diffusion studies. Results: The multi-compartmental transdermal patch showed sustained drug release over the period of 12 h. Conclusions: Multicompartmental transdermal patches shows better bioavailability, therapeutic efficacy and very economic as compared with other dosage forms.

  19. Penetration Evaluation of Explosively Formed Projectiles Through Air and Water Using Insensitive Munition: Simulative and Experimental Studies

    National Research Council Canada - National Science Library

    M. Ahmed; A. Q. Malik; S. A. Rofi; Z. X. Huang

    2016-01-01

    The process of formation, flying, penetration of explosively-formed projectiles (EFP) and the effect of water on performance of the charge for underwater applications is simulated by Ansysis Autodyn 2D-Hydro code...

  20. Impression evaluation and laboratory use for single-unit crowns: Findings from The National Dental Practice-Based Research Network.

    Science.gov (United States)

    McCracken, Michael S; Litaker, Mark S; George, Ashley J; Durand, Scott; Malekpour, Sepideh; Marshall, Don G; Meyerowitz, Cyril; Carter, Lauren; Gordan, Valeria V; Gilbert, Gregg H

    2017-08-16

    Objectives were to determine the likelihood that a clinician accepts an impression for a single-unit crown and document crown remake rates. The authors developed a questionnaire that asked dentists about techniques used to fabricate single-unit crowns. The authors showed dentists photographs of 4 impressions and asked them to accept or reject each impression. The authors correlated answers with dentist and practice characteristics. Other questions pertained to laboratory use and crown remake rates. The response rate was 83% (1,777 of 2,132 eligible dentists). Of the 4 impressions evaluated, 3 received consistent responses, with 85% agreement. One impression was more equivocal; 52% accepted the impression. The likelihood of accepting an impression was associated significantly with the clinician's sex, race, ethnicity, and practice busyness. Clinicians produced 18 crowns per month on average, and 9% used in-office milling. Most dentists (59%) reported a remake rate of less than 2%, whereas 17% reported a remake rate greater than 4%. Lower remake rates were associated significantly with more experienced clinicians, optical impressions, and not using dual-arch trays. Although dentists were largely consistent in their evaluation of impressions (> 85%), nonclinical factors were associated with whether an impression was accepted or rejected. Lower crown remake rates were associated with more experienced clinicians, optical impressions, and not using dual-arch trays. These results provide a snapshot of clinical care considerations among a diverse group of dentists. Clinicians can compare their own remake rates and impression evaluation techniques with those in this sample when developing best practice protocols. Copyright © 2017 American Dental Association. Published by Elsevier Inc. All rights reserved.

  1. Evaluating the effectiveness of ultraviolet-C lamps for reducing keyboard contamination in the intensive care unit: A longitudinal analysis.

    Science.gov (United States)

    Gostine, Andrew; Gostine, David; Donohue, Cristina; Carlstrom, Luke

    2016-10-01

    Ultraviolet (UV) spectrum light for decontamination of patient care areas is an effective way to reduce transmission of infectious pathogens. Our purpose was to investigate the efficacy of an automated UV-C device to eliminate bioburden on hospital computer keyboards. The study took place at an academic hospital in Chicago, Illinois. Baseline cultures were obtained from keyboards in intensive care units. Automated UV-C lamps were installed over keyboards and mice of those computers. The lamps were tested at varying cycle lengths to determine shortest effective cycles. Delay after use and prior to cycle initiation was varied to minimize cycle interruptions. Finally, 218 postinstallation samples were analyzed. Of 203 baseline samples, 193 (95.1%) were positive for bacteria, with a median of 120 colony forming units (CFU) per keyboard. There were numerous bacteria linked to health care-associated infections (HAIs), including Staphylococcus, Streptococcus, Enterococcus, Pseudomonas, Pasteurella, Klebsiella, Acinetobacter, and Enterobacter. Of the 193 keyboards, 25 (12.3%) had gram-negative species. Of 218 postinstallation samples, 205 (94%) were sterile. Of the 13 that showed bacterial growth, 6 produced a single CFU. Comparison of pre- and post-UV decontamination median CFU values (120 and 0, respectively) revealed a >99% reduction in bacteria. The UV lamp effectively decontaminates keyboards with minimal interruption and low UV exposure. Further studies are required to determine reduction of HAI transmission with use of these devices. Copyright © 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  2. Intersecting gender, evaluations, and examinations: Averting gender bias in an obstetrics and gynecology clerkship in the United States.

    Science.gov (United States)

    Jacques, Laura; Kaljo, Kristina; Treat, Robert; Davis, Joseph; Farez, Rahmouna; Lund, Michael

    2016-01-01

    The purpose of this study was to determine whether gender bias was present in the final third-year medical student obstetrics/gynecology clerkship performance evaluation completed by faculty and resident physicians. This was a retrospective cohort study of third-year medical students over the course of ten years (2004 - 2014) at a private medical school in the northern US state of Wisconsin. Each student's performance during their required 6-week obstetrics/gynecology clerkship was assessed by a combination of the student's scores on a clinical performance evaluation and on a standardized national subject examination. The clinical performance evaluations are comprised of 10 domains, each using a 9-point Likert scale and completed by faculty and resident physicians. All clerkships at our institution use the same evaluation form, which was designed and validated by the medical education statistics department. Final obstetrics/gynecology clerkship average clinical evaluation scores (Scale 1-9) and obstetrics/gynecology standardized national subject examination scores (Percentile 1-99) were compared to see if a gender based difference between subject examination and performance evaluation scores existed. 1,976 student records were analyzed. Mean standardized national subject exam scores were significantly higher for females [74.4 (8.1)] than males [72.9 (8.2)] (Possible range 1-99) with Cohen's d = 0.2 (P = 0.001). The average female score on the clinical evaluation was mean (SD) = 7.4 (0.9), compared to an average clinical evaluation score of 7.2 (1.0) for males (P = 0.001) (range 1-9). Performance on the standardized national subject exam was significantly correlated (r = 0.3, P = 0.001) with clinical evaluation scores, and when split by gender the strength of the correlation remained. Medical student performance on the standardized national subject exam correlated with clinical evaluations independent of gender. Women had higher scores on both the subject

  3. A Risk-Based Strategy for Evaluating Mitigation Options for Process-Formed Compounds in Food: Workshop Proceedings.

    Science.gov (United States)

    Hanlon, Paul; Brorby, Gregory P; Krishan, Mansi

    2016-05-01

    Processing (eg, cooking, grinding, drying) has changed the composition of food throughout the course of human history; however, awareness of process-formed compounds, and the potential need to mitigate exposure to those compounds, is a relatively recent phenomenon. In May 2015, the North American Branch of the International Life Sciences Institute (ILSI North America) Technical Committee on Food and Chemical Safety held a workshop on the risk-based process for mitigation of process-formed compounds. This workshop aimed to gain alignment from academia, government, and industry on a risk-based process for proactively assessing the need for and benefit of mitigation of process-formed compounds, including criteria to objectively assess the impact of mitigation as well as research needed to support this process. Workshop participants provided real-time feedback on a draft framework in the form of a decision tree developed by the ILSI North America Technical Committee on Food and Chemical Safety to a panel of experts, and they discussed the importance of communicating the value of such a process to the larger scientific community and, ultimately, the public. The outcome of the workshop was a decision tree that can be used by the scientific community and could form the basis of a global approach to assessing the risks associated with mitigation of process-formed compounds.

  4. A clinical chemistry analyzer evaluated by NCCLS guidelines for use in a military field laboratory unit.

    Science.gov (United States)

    Sullinger, J; Garrett, P E

    1989-11-01

    In a previous comparison study of "dry chemistry" desktop analyzers, the ChemPro 1000 (Arden Medical Systems) was one of several instruments found suitable for field use. We have now evaluated the linearity, accuracy, and precision of the ChemPro 1000, according to NCCLS Document EP 10-P. We also compared results with those by the SMAC (Technicon) and the Nova 9 (Nova Biomedical) for electrolytes, serum urea nitrogen, and ionized calcium in field and laboratory environments. The precision (CV) of the ChemPro was within acceptable ranges for dry chemistry desktop analyzers for all analytes tested. This instrument is a suitable and reasonable alternative to manual chemistry or to large, automated instrumentation in a field environment.

  5. Evaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study.

    LENUS (Irish Health Repository)

    Mahdy, Saad

    2009-06-01

    Anemia is a common problem in the ICU population. Most patients are anemic at admission, their hemoglobin concentrations declining further thereafter. The aim of the present study was to evaluate the effect of a combination strategy, involving closed arterial blood gas sampling and the use of pediatric vials for phlebotomy (Group A), on the sampling-induced blood loss and the rate of decline in hemoglobin in adult ICU patients. Combination (Group A) was compared to the current standard technique of arterial line sampling and adult vial phlebotomy (Group B) in a prospective, randomised, ethically-approved trial for the first 72 hours of their ICU stay. Peri-operative, oncology, coagulopathic and uremic patients were excluded. All other ICU patients with arterial cannulae and predicted to stay beyond 3 days, were enrolled.

  6. Eco-Efficiency Model for Evaluating Feedlot Rations in the Great Plains, United States.

    Science.gov (United States)

    Hengen, Tyler J; Sieverding, Heidi L; Cole, Noel A; Ham, Jay M; Stone, James J

    2016-07-01

    Environmental impacts attributable to beef feedlot production provide an opportunity for economically linked efficiency optimization. Eco-efficiency models are used to optimize production and processes by connecting and quantifying environmental and economic impacts. An adaptable, objective eco-efficiency model was developed to assess the impacts of dietary rations on beef feedlot environmental and fiscal cost. The hybridized model used California Net Energy System modeling, life cycle assessment, principal component analyses (PCA), and economic analyses. The model approach was based on 38 potential feedlot rations and four transportation scenarios for the US Great Plains for each ration to determine the appropriate weight of each impact. All 152 scenarios were then assessed through a nested PCA to determine the relative contributing weight of each impact and environmental category to the overall system. The PCA output was evaluated using an eco-efficiency model. Results suggest that water, ecosystem, and human health emissions were the primary impact category drivers for feedlot eco-efficiency scoring. Enteric CH emissions were the greatest individual contributor to environmental performance (5.7% of the overall assessment), whereas terrestrial ecotoxicity had the lowest overall contribution (0.2% of the overall assessment). A well-balanced ration with mid-range dietary and processing energy requirements yielded the most eco- and environmentally efficient system. Using these results, it is possible to design a beef feed ration that is more economical and environmentally friendly. This methodology can be used to evaluate eco-efficiency and to reduce researcher bias of other complex systems.

  7. Evaluative conditioning of high-novelty stimuli does not seem to be based on an automatic form of associative learning

    NARCIS (Netherlands)

    Dedonder, Jonathan; Corneille, Olivier; Yzerbyt, Vincent; Kuppens, Toon

    2010-01-01

    Evaluative conditioning (EC) refers to the change in valence of initially neutral stimuli (conditioned stimuli, or CSs) as a result of their pairing with positive or negative stimuli (unconditioned stimuli, or USs). EC is critical to dual-attitudes models as it is often presented as an evaluative

  8. Evaluative conditioning of high-novelty stimuli does not seem to be based on an automatic form of associative learning

    NARCIS (Netherlands)

    Dedonder, Jonathan; Corneille, Olivier; Yzerbyt, Vincent; Kuppens, Toon

    2010-01-01

    Evaluative conditioning (EC) refers to the change in valence of initially neutral stimuli (conditioned stimuli, or CSs) as a result of their pairing with positive or negative stimuli (unconditioned stimuli, or USs). EC is critical to dual-attitudes models as it is often presented as an evaluative ef

  9. An evaluation of current methods of diagnosing colorectal cancer in the United Kingdom

    Energy Technology Data Exchange (ETDEWEB)

    Bond, Janet [Band 6 Radiographer, X-ray West, Derriford Hospital, Derriford Road, Plymouth PL6 8DH (United Kingdom)], E-mail: janbon25@hotmail.com; Tuckey, Mandy [Radiotherapy, Room 2K06, Glenside Campus, University of the West of England, Faculty of Health and Social Care, Blackberry Hill, Stapleton, Bristol BS16 1DD (United Kingdom)], E-mail: mandy.tuckey@uwe.ac.uk

    2009-05-15

    Colorectal cancer (CRC) is a highly conversed topic, particularly since implementation of screening for CRC is imminent within the U.K. Aims: The aim of this research project was to examine the diagnostic tools currently used within the UK to detect CRC and their impact on the aetiology and epidemiology of CRC. Methodology: The complexity of the research topic lent itself towards a literature review. A systematic approach of researching was therefore adopted to analyse and critically evaluate the reliability and validity of articles. Electronic databases including AMED, Cancerlit, CINHAL, the Cochrane Library, EMBASE, MEDLINE and EBM-Reviews were utilised to provide a wide spectrum of recent and relevant articles. Other research strategies involved looking for books relating to the topics, which were kept to within 6 years of publication to maintain accuracy of information. Selected websites, such as NICE, the Department of Health, NHS websites and Cancer Research U.K. were useful at explaining current and future screening plans and trials within Britain and allowed the study of reliable U.K. statistics. The research articles were then outlined and placed into sections of similar topic areas, which enabled the author to compare, contrast and evaluate the hypotheses. By organising the research in this way, a thorough review of the existing research for CRC was resultant. Results: A range of diagnostic tools is currently in use for detecting CRC within the UK. Screening for asymptomatic individuals aged 55-60 years+, (the age range where CRC incidence is higher), would provide the most effective reduction in CRC incidence and mortality rates. Conclusions: The use of a multi-phasic screening programme consisting of faecal occult blood tests (FOBt) and a whole bowel examination is considered to be the most effective diagnostic tools. However, preventative schemes, such as better education of the risks and symptoms of CRC, supported by the NHS Cancer Plan (2000), have

  10. Design, Fabrication and pseudo Field Evaluation of a Sugar Beet Crust Breaker and Weeding Unit Equipped with an Infrared Sensor

    Directory of Open Access Journals (Sweden)

    E Chaligar

    2014-09-01

    Full Text Available In conventional cultivation of sugar beet the weeding and crust breaking are mostly performed manually. The objectives of this research were to design, fabricate and evaluate a soil crust breaker and weeding implement equipped with a detecting sensor. Each unit consisted of a distance detecting sensor and a hydro-motor for driving the blades and pneumatic valves for moving the blades. The hydro-motor was activated by the sensors. To avoid damaging the plants, a command signal was sent to the pneumatic valves to move the blades up and down and pass safely. Three configurations of cutting blades were considered which could be mounted to the crust breaker. The field evaluation was conducted with two tractor forward speeds (0.4 and 1 km h-1 and four plant-to-plant spacings within rows (20, 25, 30 and 40 cm all with three different blade shapes. For field evaluation split plot experiments arranged in a completely randomized block design with three replications. The number of plants damaged (evaluated only for four-lobe blades and size of broken crusts (evaluated for all blade shapes for various treatments were recorded and compared. The results of analysis indicated that the higher the inter-row spacing the lower the injury to the plant. The highest and the least damage to the plants occurred for within-row plant spacings of 20 and 40 cm, respectively. The forward speed was also significantly affected the percent of plant damaged. The forward speed of 1 km h-1 at 20 cm spacing had the most (59% and the speed of 0.40 km h-1 at 40 cm spacing had the least effect (3.3% on the percent of plant damage. The two-lobe blade could result in the maximum surface area broken.

  11. The Greek immigrant family in the United States and Canada: the transition from an "institutional" to a "relational" form (1945-1970).

    Science.gov (United States)

    Tastsoglou, E; Stubos, G

    1992-06-01

    "This paper attempts to provide a...comprehensive understanding of changes in the form, practices and values that took place in the Greek immigrant family in North America after World War II. Selected theoretical presuppositions will be followed by a discussion of the form and intra-family relations in the Greek immigrant family from 1945 to 1970. Finally,...the characteristics of Greek immigrants from the 1880s to the end of the Great Depression...will be offered." (SUMMARY IN FRE AND SPA)

  12. Evaluation of the United States Support Program’s Internship and Junior Professional Officer Programs

    Energy Technology Data Exchange (ETDEWEB)

    Cruz J.; Patterson, J.; Pepper, S.

    2012-07-15

    The U.S. Support Program (USSP) to International Atomic Energy Agency (IAEA) Safeguards established a program of one-year paid internships for students and recent graduates. The program was in effect from 2002 until 2006 with a total of forty-one U.S. citizens and permanent residents placed in the IAEA. The USSP created a Junior Professional Officer (JPO) Program in 2005 that replaced the internship program at the IAEA. The JPO program creates opportunities for U.S. college graduates to become IAEA employees for a period of one to two years to help increase the effectiveness and efficiency of safeguards. The twenty three former and current JPOs work in varying fields such as software development, information collection and analysis, non-destructive analysis systems, and unattended monitoring systems. This paper will look at the impacts of the USSP internship and JPO program on the interns and JPOs, the U.S. government, and the IAEA. Academic backgrounds, past involvement in nuclear fields, program assessment, and post-program positions were recorded and analyzed through two studies using questionnaires sent to former interns and former and current JPOs. This paper will discuss the effects of the programs on the careers of the interns and JPOs, present the evaluations of the internship and JPO Programs, and report the recommendations for changes.

  13. [Nuclear magnetic resonance based metabolic phenotyping for patient evaluations in operating rooms and intensive care units].

    Science.gov (United States)

    Blaise, B J; Gouel-Chéron, A; Floccard, B; Monneret, G; Plaisant, F; Chassard, D; Javouhey, E; Claris, O; Allaouchiche, B

    2014-03-01

    Metabolic phenotyping consists in the identification of subtle and coordinated metabolic variations associated with various pathophysiological stimuli. Different analytical methods, such as nuclear magnetic resonance, allow the simultaneous quantification of a large number of metabolites. Statistical analyses of these spectra thus lead to the discrimination between samples and the identification of a metabolic phenotype corresponding to the effect under study. This approach allows the extraction of candidate biomarkers and the recovery of perturbed metabolic networks, driving to the generation of biochemical hypotheses (pathophysiological mechanisms, diagnostic tests, therapeutic targets…). Metabolic phenotyping could be useful in anaesthesiology and intensive care medicine for the evaluation, monitoring or diagnosis of life-threatening situations, to optimise patient managements. This review introduces the physical and statistical fundamentals of NMR-based metabolic phenotyping, describes the work already achieved by this approach in anaesthesiology and intensive care medicine. Finally, potential areas of interest are discussed for the perioperative and intensive management of patients, from newborns to adults. Copyright © 2013 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

  14. Evaluation of spin freezing versus conventional freezing as part of a continuous pharmaceutical freeze-drying concept for unit doses.

    Science.gov (United States)

    De Meyer, L; Van Bockstal, P-J; Corver, J; Vervaet, C; Remon, J P; De Beer, T

    2015-12-30

    Spin-freezing as alternative freezing approach was evaluated as part of an innovative continuous pharmaceutical freeze-drying concept for unit doses. The aim of this paper was to compare the sublimation rate of spin-frozen vials versus traditionally frozen vials in a batch freeze-dryer, and its impact on total drying time. Five different formulations, each having a different dry cake resistance, were tested. After freezing, the traditionally frozen vials were placed on the shelves while the spin-frozen vials were placed in aluminum vial holders providing radial energy supply during drying. Different primary drying conditions and chamber pressures were evaluated. After 2h of primary drying, the amount of sublimed ice was determined in each vial. Each formulation was monitored in-line using NIR spectroscopy during drying to determine the sublimation endpoint and the influence of drying conditions upon total drying time. For all tested formulations and applied freeze-drying conditions, there was a significant higher sublimation rate in the spin-frozen vials. This can be explained by the larger product surface and the lower importance of product resistance because of the much thinner product layers in the spin frozen vials. The in-line NIR measurements allowed evaluating the influence of applied drying conditions on the drying trajectories.

  15. Comparision of GCS and FOUR scores used in the evaluation of neurological status in intensive care units

    Directory of Open Access Journals (Sweden)

    Ayca Sultan sahin

    2015-09-01

    Full Text Available Objective: The Glasgow Coma Scale (GCS is the most widely used scoring system to evaluation of neurological status for patients in intensive care unit. Limitations of the GCS include severe to assess the verbal score in intubated or aphasic patients. The Full Outline of UnResponsiveness score (FOUR, a new coma scale not reliant on verbal response, was recently proposed. New scales strongly suggest a scale is needed that could provide further nerological detail that is easy to use. We aimed to compare FOUR score and GCS among unselected patients in intensive care units and comparerealibility betweenobservers. Material-Methods: In our study 105 patients was admitted. Three different types of examiners tested FOUR score and GCS: one intensive care unit nurse, one anaesthesiology resident (2. year, and one anaesthesiology fellow. Patients receiving sedative agents or neuromuscular function blockers were excluded. The raters performed their examination within 1 hour of each other without knowledge of the others scores. Results: In our study compared the interrater agreement of GCS and FOUR score. Although FOUR score was thought to be superior in aphasic and intubated patients, there was neither a statistical significant difference between the GCS and the FOUR score nor a difference among ICU staff. Conclusion: As a result, the scores that used in ICUs, should be simple, reliable and predictive. Our study revealed that the FOUR score is at least equivalent to the GCS. And for us, GCS and FOUR scores are easy to use both doctors and nurses. [J Contemp Med 2015; 5(3.000: 167-172

  16. Evaluation of the Medical Care of Patients with Hypertension in an Emergency Department and in Ambulatory Hypertension Unit

    Directory of Open Access Journals (Sweden)

    Fernando Nobre

    2002-02-01

    Full Text Available OBJECTIVE: To evaluate the characteristics of the patients receiving medical care in the Ambulatory of Hypertension of the Emergency Department, Division of Cardiology, and in the Emergency Unit of the Clinical Hospital of the Ribeirão Preto Medical School. METHODS: Using a protocol, we compared the care of the same hypertensive patients in on different occasions in the 2 different places. The characteristics of 62 patients, 29 men with a mean age of 57 years, were analyzed between January 1996 and December 1997. RESULTS: The care of these patients resulted in different medical treatment regardless of their clinical features and blood pressure levels. Thus, in the Emergency Unit, 97% presented with symptoms, and 64.5% received medication to rapidly reduce blood pressure. In 50% of the cases, nifedipine SL was the elected medication. Patients who applied to the Ambulatory of Hypertension presenting with similar features, or, in some cases, presenting with similar clinically higher levels of blood pressure, were not prescribed medication for a rapid reduction of blood pressure at any of the appointments. CONCLUSION: The therapeutic approach to patients with high blood pressure levels, symptomatic or asymptomatic, was dependent on the place of treatment. In the Emergency Unit, the conduct was, in the majority of cases, to decrease blood pressure immediately, whereas in the Ambulatory of Hypertension, the same levels of blood pressure, in the same individuals, resulted in therapeutic adjustment with nonpharmacological management. These results show the need to reconsider the concept of hypertensive crises and their therapeutical implications.

  17. Evaluation of Selected Resource Allocation and Scheduling Methods in Heterogeneous Many-Core Processors and Graphics Processing Units

    Directory of Open Access Journals (Sweden)

    Ciznicki Milosz

    2014-12-01

    Full Text Available Heterogeneous many-core computing resources are increasingly popular among users due to their improved performance over homogeneous systems. Many developers have realized that heterogeneous systems, e.g. a combination of a shared memory multi-core CPU machine with massively parallel Graphics Processing Units (GPUs, can provide significant performance opportunities to a wide range of applications. However, the best overall performance can only be achieved if application tasks are efficiently assigned to different types of processor units in time taking into account their specific resource requirements. Additionally, one should note that available heterogeneous resources have been designed as general purpose units, however, with many built-in features accelerating specific application operations. In other words, the same algorithm or application functionality can be implemented as a different task for CPU or GPU. Nevertheless, from the perspective of various evaluation criteria, e.g. the total execution time or energy consumption, we may observe completely different results. Therefore, as tasks can be scheduled and managed in many alternative ways on both many-core CPUs or GPUs and consequently have a huge impact on the overall computing resources performance, there are needs for new and improved resource management techniques. In this paper we discuss results achieved during experimental performance studies of selected task scheduling methods in heterogeneous computing systems. Additionally, we present a new architecture for resource allocation and task scheduling library which provides a generic application programming interface at the operating system level for improving scheduling polices taking into account a diversity of tasks and heterogeneous computing resources characteristics.

  18. Economic evaluation of United States ethanol production from ligno-cellulosic feedstocks

    Science.gov (United States)

    Choi, Youn-Sang

    This paper evaluates the economic feasibility and economy-wide impacts of the U. S. ethanol production from lignocellulosic feedstocks (LCF) using Tennessee Valley Authority's (TVA's) dilute acid hydrolysis process. A nonlinear mathematical programming model of a single ethanol producer, whose objective is profit maximization, is developed. Because of differences in their chemical composition and production process, lignocellulosic feedstocks are divided into two groups: Biomass feedstocks, which refer to crop residues, energy crops and woody biomass, and municipal solid waste (MSW). Biomass feedstocks are more productive and less costly in producing ethanol and co-products, while MSW generates an additional income to the producer from a tipping fee and recycling. The analysis suggests that, regardless of types of feedstocks used, TVA's conversion process can enhance the economic viability of ethanol production as long as furfural is produced from the hemicellulose fraction of feedstocks as a co-product. The high price of furfural makes it a major factor in determining the economic feasibility of ethanol production. Along with evaluating economic feasibility of LCF-to-ethanol production, the optimal size of a plant producing ethanol using TVA's conversion process is estimated. The larger plant would have the advantage of economies of scale, but also have a disadvantage of increased collection and transportation costs for bulky biomass from more distant locations. We assume that the plant is located in the state of Missouri and utilizes only feedstocks produced in the state. The results indicate that the size of a plant using Biomass feedstocks is much bigger than one using MSW. The difference of plant sizes results from plant location and feedstock availability. One interesting finding is that energy crops are not feasible feedstocks for LCF-to-ethanol production due to their high price. Next, a static CGE model is developed to estimate the U.S. economy

  19. Evaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study.

    LENUS (Irish Health Repository)

    Mahdy, Saad

    2012-02-01

    OBJECTIVE AND METHODS: Anemia is a common problem in the ICU population. Most patients are anemic at admission, their hemoglobin concentrations declining further thereafter. The aim of the present study was to evaluate the effect of a combination strategy, involving closed arterial blood gas sampling and the use of pediatric vials for phlebotomy (Group A), on the sampling-induced blood loss and the rate of decline in hemoglobin in adult ICU patients. Combination (Group A) was compared to the current standard technique of arterial line sampling and adult vial phlebotomy (Group B) in a prospective, randomised, ethically-approved trial for the first 72 hours of their ICU stay. Peri-operative, oncology, coagulopathic and uremic patients were excluded. All other ICU patients with arterial cannulae and predicted to stay beyond 3 days, were enrolled. RESULTS: 39 patients entered the study, 20 in Group A, and 19 in Group B. Data collection was complete for all. There was a statistically significant difference in sampling-induced blood loss between the groups over the first 72 hours of treatment (mean +\\/- standard deviation: 15.16 +\\/- 5.3 ml Group A vs 45.11 +\\/- 14 ml Group B, p<0.001). There was a smaller decline in mean hemoglobin level, which was not statistically significant (0.79 +\\/- 0.6 g\\/dL vs 1.30 +\\/- 1.13, p = 0.09). CONCLUSIONS: Overall, this strategy reduced measurable blood losses from phlebotomy. In larger trials it might also preserve hemoglobin levels.

  20. Economic evaluation of the routine childhood immunization program in the United States, 2009.

    Science.gov (United States)

    Zhou, Fangjun; Shefer, Abigail; Wenger, Jay; Messonnier, Mark; Wang, Li Yan; Lopez, Adriana; Moore, Matthew; Murphy, Trudy V; Cortese, Margaret; Rodewald, Lance

    2014-04-01

    To evaluate the economic impact of the 2009 routine US childhood immunization schedule, including diphtheria and tetanus toxoids and acellular pertussis, Haemophilus influenzae type b conjugate, inactivated poliovirus, measles/mumps/rubella, hepatitis B, varicella, 7-valent pneumococcal conjugate, hepatitis A, and rotavirus vaccines; influenza vaccine was not included. Decision analysis was conducted using population-based vaccination coverage, published vaccine efficacies, historical data on disease incidence before vaccination, and disease incidence reported during 2005 to 2009. Costs were estimated using the direct cost and societal (direct and indirect costs) perspectives. Program costs included vaccine, administration, vaccine-associated adverse events, and parent travel and work time lost. All costs were inflated to 2009 dollars, and all costs and benefits in the future were discounted at a 3% annual rate. A hypothetical 2009 US birth cohort of 4,261,494 infants over their lifetime was followed up from birth through death. Net present value (net savings) and benefit-cost ratios of routine childhood immunization were calculated. Analyses showed that routine childhood immunization among members of the 2009 US birth cohort will prevent ∼42,000 early deaths and 20 million cases of disease, with net savings of $13.5 billion in direct costs and $68.8 billion in total societal costs, respectively. The direct and societal benefit-cost ratios for routine childhood vaccination with these 9 vaccines were 3.0 and 10.1. From both direct cost and societal perspectives, vaccinating children as recommended with these vaccines results in substantial cost savings.

  1. Economic evaluation of the 7-vaccine routine childhood immunization schedule in the United States, 2001.

    Science.gov (United States)

    Zhou, Fangjun; Santoli, Jeanne; Messonnier, Mark L; Yusuf, Hussain R; Shefer, Abigail; Chu, Susan Y; Rodewald, Lance; Harpaz, Rafael

    2005-12-01

    To evaluate the economic impact of the routine US childhood immunization schedule: diphtheria and tetanus toxoids and acellular pertussis; tetanus and diphtheria toxoids; Haemophilus influenzae type b conjugate; inactivated poliovirus; measles, mumps, and rubella; hepatitis B; and varicella vaccines. Decision tree-based analysis was conducted using population-based vaccination coverage, published vaccine efficacies, historical data on disease incidence before vaccination, and disease incidence reported for 1995-2001. Costs were estimated using the direct cost and societal (direct and indirect costs) perspectives. Program costs included vaccine, administration, vaccine-associated adverse events, and parent travel and time lost. All costs were inflated to 2001 US dollars, and all costs and benefits in the future were discounted at a 3% annual rate. A hypothetical 2001 US birth cohort of 3,803,295 infants was followed up from birth through death. Net present value (net savings) and benefit-cost ratios of routine immunization. Routine childhood immunization with the 7 vaccines was cost saving from the direct cost and societal perspectives, with net savings of 9.9 billion dollars and 43.3 billion dollars, respectively. Without routine vaccination, direct and societal costs of diphtheria, tetanus, pertussis, H influenzae type b, poliomyelitis, measles, mumps, rubella, congenital rubella syndrome, hepatitis B, and varicella would be 12.3 billion dollars and 46.6 billion dollars, respectively. Direct and societal costs for the vaccination program were an estimated 2.3 billion dollars and 2.8 billion dollars, respectively. Direct and societal benefit-cost ratios for routine childhood vaccination were 5.3 and 16.5, respectively. Regardless of the perspective, the current routine childhood immunization schedule results in substantial cost savings.

  2. Intensification of the Learning Process: Diagnostic Instruments--Learner State Check List Evaluation Response Form. A Series of Reports Designed for Classroom Use.

    Science.gov (United States)

    Bucks County Public Schools, Doylestown, PA.

    Check lists for determining the pupils' position along a curriculum scale are presented. A behavioral objectives evaluation response form is included. (See TM 001 363 for summary report of the project; for other related documents, see TM 001 160, 364, 366-374.) (MS)

  3. Evaluation of the Utility of the Edmonton Symptom Assessment System (revised) Scale on a Tertiary Palliative Care Unit.

    Science.gov (United States)

    Beddard-Huber, Elizabeth; Jayaraman, Jyothi; White, Laura; Yeomans, Wendy

    2015-01-01

    The aim of this study was to evaluate the utility of the Edmonton Symptom Assessment System (ESAS-r) Scale on a tertiary palliative care unit. There were 92 admitted patients who participated in the study; the scale was administered to those able to participate on day 1 (n = 35, 38 percent), on day 4 (n = 20, 21 percent), and weekly. Patient comfort level with the ESAS-r tool was assessed using a 5-point Likert scale (strongly disagree to strongly agree) on day 4. Nurses' and physicians' perceptions of clinical assessment pre- and postimplementation of the scale were surveyed using a 5-point Likert scale. Of the participating physicians, 75 percent (n = 3) found that the ESAS-r Scale did not enhance clinical assessment; the proportion of nurses with that response was 37.5 percent (n = 6). Among these care providers, 50 percent of the physicians (n = 2) and 62 percent of the nurses (n = 10) thought that the scale was burdensome to patients; but 60 percent of the patients who were able to complete the comfort-level survey (n = 12) indicated that they did not find the scale burdensome. Patient acuity, team expertise, perceived burden to patients, and time commitment all influenced staff's recommendation not to implement the ESAS-r tool on the palliative care unit.

  4. Evaluation of aquifer protective capacity of overburden unit and soil corrosivity in Makurdi, Benue state, Nigeria, using electrical resistivity method

    Indian Academy of Sciences (India)

    Daniel N Obiora; Adeolu E Ajala; Johnson C Ibuot

    2015-02-01

    This paper presents result of 30 vertical electrical soundings carried out in Makurdi, Benue state capital, north–central Nigeria to evaluate aquifer protective capacity and soil corrosivity of overburden units in the study area. This was done using the Schlumberger electrode array to obtain the data and was modelled using computer iteration (Winresist software). The field data gives a resolution with 3–4 geoelectric layers and the observed frequencies in curve types include: 30% of KQ, 16.67% of QH, 6.67% of AA and K, 3.33% of HA, Q and A, 10% of H, KH and HK. Using the longitudinal unit conductance (S), the protective capacities of the study area were classified as 36.67% weak, 10% poor, 40% moderate, and 13.33% as good. The corrosivity ratings of the study area show that 10% is strongly corrosive, 23% moderately corrosive, 37% slightly corrosive, and 30% noncorrosive The results reasonably provide information on areas where industries can be sited and iron pipes can be laid in order to safeguard the hydrological setting for resident’s safety in the study area. Regions with moderate/good protective capacity are good sites for locating boreholes.

  5. Patient dosimetry activities in the United States: the nationwide evaluation of X-ray trends (NEXT) and tissue dose handbooks.

    Science.gov (United States)

    Suleiman, O H; Stern, S H; Spelic, D C

    1999-01-01

    In the United States the Food and Drug Administration (FDA) in collaboration with the Conference of Radiation Control Program Directors (CRCPD) and state and local government agencies surveys clinical facilities about X-ray system air kerma and ancillary data related to patient dosimetry for a variety of diagnostic X-ray examinations. The survey program is known as the Nationwide Evaluation of X-ray Trends (NEXT). The survey utilizes reference patient-equivalent phantoms in the collection of comprehensive technical information. With knowledge of the skin-entrance air kerma, specific tissue doses can be calculated. An overview of NEXT and previously published FDA tissue dose handbooks for diagnostic X-ray examinations is presented.

  6. Evaluation and targeting of geothermal energy resources in the southeastern United States. Progress report, October 1--December 31, 1977

    Energy Technology Data Exchange (ETDEWEB)

    Costain, J.K.; Glover, L. III; Krishna Sinha, A.

    1977-01-01

    Progress in the evaluation of low-temperature geothermal resources in the eastern United States utilizing geological, geochemical, and geophysical data is reported. Primary programmatic emphasis is now being placed on the confirmation of radiogenic resources beneath sediments of the Atlantic Coastal Plain. Collation of existing gravity and magnetic data available for the Atlantic Coastal Plain is complete, and modeling of selected negative gravity anomalies of the Cuffytown Creek (Edgefield) pluton, S.C., the Rolesville batholith, N.C., and the Petersburg granite, Va., is in progress. Maps showing the distribution of gravity stations for the states of Georgia, South Carolina, and North Carolina were prepared. A reconnaissance geologic map is being prepared of the Raleigh belt and Carolina slate belt rocks. The purpose of this study is to determine the relationship of the Rolesville batholith to the surrounding country rocks, and to provide a geologic base for the geophysical interpretation of Piedmont stratigraphy underlying Atlantic Coastal Plain sediments to the east.

  7. A note on the evaluation of the guest-gas uptake into a clathrate hydrate being formed in a semibatch- or batch-type reactor

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Yasuhiko H.; Komae, Naoya [Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522 (Japan)

    2008-05-15

    This paper deals with the principle of determining the rate of guest-gas uptake into a clathrate hydrate being formed in a semibatch-type isobaric reactor or a batch-type closed reactor on the basis of experimental data for the guest-gas supply into the reactor or the pressure change inside the reactor. The specific issue considered here is the possible necessity of taking into account the effect of the change in the total volume of the condensed (liquid + hydrate) phases inside the reactor during each hydrate-forming operation. General schemes for evaluating this effect in semibatch and batch operations are formulated and applied to some specific hydrate-forming operations to evaluate the effect on estimating the guest-gas uptake into the hydrate. (author)

  8. Intra-Service Section 7 Biological Evaluation Form : [2010 Proposed Hunting Plan for Sherburne National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Section 7 Evaluation states that the Sherburne NWR Hunting Plan will have no effect on listed/proposed/candidate species or the critical habitat of these species.

  9. Patoka River National Wildlife Refuge & Management Area Hunting and Fishing Plan : Intra-Service Section 7 Evaluation Form

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Section 7 Evaluation states that the Patoka River NWR Hunting and Fishing Plan is not likely to adversely affect listed species or critical habitats on the...

  10. Image forming apparatus

    DEFF Research Database (Denmark)

    2005-01-01

    An image H(x, y) for displaying a target image G(x, y) is displayed on a liquid-crystal display panel and illumination light from an illumination light source is made to pass therethrough to form an image on a PALSLM. Read light hv is radiated to the PALSLM and a phase-modulated light image alpha...... (x, y) read out of the PALSLM is subjected to Fourier transform by a lens. A phase contrast filter gives a predetermined phase shift to only the zero-order light component of Fourier light image alpha f(x, y). The phase-shifted light image is subjected to inverse Fourier transform by a lens...... to project an output image O(x, y) to an output plane. A light image O'(x, y) branched by a beam sampler is picked up by a pickup device and an evaluation value calculating unit evaluates conformity between the image O(x, y) and the image G(x, y).; A control unit performs feedback control of optical...

  11. Evaluation of strategic actions in the health of the elderly in Basic Health Units of Teresina-PI

    Directory of Open Access Journals (Sweden)

    Larissa Almondes da Luz

    2012-02-01

    Full Text Available Each year, about 650,000 elderly people are incorporated to the population, raising the necessity to reorganize, primarily, the social models in order to meet decent health care standards for the aging population. These models seek to recover, maintain and promote autonomy and independence, directing individual and collective health measures to this end. The purpose of this research was to evaluate the strategic actions in the health care of the elderly in Basic Health Units (BHU in Teresina, State of Piaui. A cross-sectional observational study was carried out through questionnaires of the ‘Modified Assessment to Improve the Quality of Family Health Strategy - Self-assessment brochures 4 and 5 - Family Health Team - Part II - HEALTH OF THE ELDERLY’ applied to the 20 BHU executive board members in Teresina, after signing the term of consent, according to resolution 196/96. It was possible to observe that 70% of the units develop collective actions, 60% develop educational activities, 100% have updated registration of elderly patients, 95% monitor vaccination to date, 50% have a complete oral examination as a routine activity, 70% are not monitored by the Dental Health Team; 70% develop examination of the body surface as a routine, 60% are involved in the training of home care workers, 65% are involved in early detection of dementia, 80% of the professionals know the National Health Policy for the Elderly (PNSPI, 80% refuse training for action development at the PNSPI, 65% do not work at the identification of disabilities. It was possible to conclude, through the evaluation of the strategic actions in health care for the elderly, that there are deficits related to the internal professional practice at the UBS system in Teresina.

  12. Evaluation of the Effect of Sociodemographic Characteristics on the Satisfaction of Mothers in Neonatal Intensive Care Units in Turkey

    Directory of Open Access Journals (Sweden)

    Fatma Yılmaz

    2016-03-01

    Full Text Available Background: Patient and parent satisfaction is a significant indicator for the evaluation of quality of care in healthcare systems. This study aimed to evaluate the effect of sociodemographic characteristics on the satisfaction of the parents of newborns admitted in neonatal intensive care units (NICUs in maternity and infant disease hospitals. Methods: This descriptive study was conducted on 113 mothers with infants admitted in the NICU of a state hospital in Turkey during April 1-September 30, 2013.Data were collected using sociodemographic questionnaire and Pediatric Quality of Life Inventory (PedsQL healthcare satisfaction scale. Data analysis was performed using descriptive statistics (mean and percentage, T-test, Mann-Whitney U test, and Kruskal-Wallis test. Results: In this study, mean score of maternal satisfaction with NICU services was 65.66±20.01. No statistically significant differences were observed between maternal age, PedsQL satisfaction subscales, and total score of satisfaction. Moreover, statistically significant associations were observed between the following variables: maternal training and total satisfaction, employment status and subscales of PedsQL, technical skills and general satisfaction, and social security status and emotional support. However, no statistically significant differences were observed between the sociodemographic characteristics of newborns, total score of satisfaction, and mean scores of PedsQL satisfaction subscales in mothers. Conclusion: According to the results of this study, level of maternal satisfaction with NICU services was higher than the international average. Therefore, it is recommended that NICU nurses offer sufficient emotional support for both mothers and neonates in this unit and allow mothers to stay with their infants during hospitalization. Furthermore, it is suggested that training programs be implemented on effective communication skills between nurses and patients.

  13. Risk factors associated with calcium oxalate urolithiasis in dogs evaluated at general care veterinary hospitals in the United States.

    Science.gov (United States)

    Okafor, Chika C; Lefebvre, Sandra L; Pearl, David L; Yang, Mingyin; Wang, Mansen; Blois, Shauna L; Lund, Elizabeth M; Dewey, Cate E

    2014-08-01

    Calcium oxalate urolithiasis results from the formation of aggregates of calcium salts in the urinary tract. Difficulties associated with effectively treating calcium oxalate urolithiasis and the proportional increase in the prevalence of calcium oxalate uroliths relative to other urolith types over the last 2 decades has increased the concern of clinicians about this disease. To determine factors associated with the development of calcium oxalate urolithiasis in dogs evaluated at general care veterinary hospitals in the United States, a retrospective case-control study was performed. A national electronic database of medical records of all dogs evaluated between October 1, 2007 and December 31, 2010 at 787 general care veterinary hospitals in the United States was reviewed. Dogs were selected as cases at the first-time diagnosis of a laboratory-confirmed urolith comprised of at least 70% calcium oxalate (n=452). Two sets of control dogs with no history of urolithiasis diagnosis were randomly selected after the medical records of all remaining dogs were reviewed: urinalysis examination was a requirement in the selection of one set (n=1808) but was not required in the other set (n=1808). Historical information extracted included urolith composition, dog's diet, age, sex, neuter status, breed size category, hospital location, date of diagnosis, and urinalysis results. Multivariable analysis showed that the odds of first-time diagnosis of calcium oxalate urolithiasis were significantly (P30 mg/dL (OR: 1.55, 1.04-2.30). Patient demographics and urinalysis results are important factors that can support risk assessment and early identification of canine oxalate urolithiasis. Therefore, periodic urolith screening and monitoring of urine parameters should be encouraged for dogs at risk of developing these uroliths.

  14. An Objective Rating Form to Evaluate Grant Proposals to the Hogg Foundation for Mental Health: A Pilot Study of Implementation

    Science.gov (United States)

    Whaley, Arthur L.

    2006-01-01

    The lack of support for mental health-related projects by private philanthropy, even among those that express an interest in mental health, is due in large part to the subjectivity of the grant review process. To address this problem, Whaley, Rodriguez, and Alexander developed the Grant Proposal Rating Form (GPRF) to make the grant review process…

  15. Psychometric Evaluation of Romanian Translations of the "Behavior Problems Inventory-01" and the "Nisonger Child Behavior Rating Form"

    Science.gov (United States)

    Mircea, Camelia E.; Rojahn, Johannes; Esbensen, Anna J.

    2010-01-01

    Psychometric properties of Romanian translations of the "Behavior Problems Inventory-01" ("BPI-01"; Rojahn, Matson, Lott, Esbensen, & Smalls, 2001) and the "Nisonger Child Behavior Rating Form" ("NCBRF"; Aman, Tasse, Rojahn, & Hammer, 1996) were explored. Respondents completed the instruments for 115…

  16. Modelling of fracture effects in the sheet metal forming based on an extended FLC evaluation method in combination with fracture criterions

    Science.gov (United States)

    Hora, P.; Gorji, M.; Berisha, B.

    2016-11-01

    The industrial based prediction in sheet metal forming bases still on the Forming Limit Diagrams (FLD) as formally proposed by Goodwin [1]. The FLD are commonly specified by the Nakajima tests and evaluated with the so called cross section method. Although widely used, the FLC concept has numerous serious limitations. In the paper the possibilities for a specific prediction of crack limits based on an extended FLC concept (X-FLC) will be discussed. The new concept demonstrates that the Nakajima tests are not only appropriate for the evaluation of the necking instability but for the detection of the real crack strains too. For the evaluation of the crack strains a local thinning method as proposed by Gorji et al. [3] is applied and tested for special 6xxx and 5xxx Al-alloys as well as for the corresponding multilayer FUSION material.

  17. Evaluation

    Institute of Scientific and Technical Information of China (English)

    Fred Genesee

    2005-01-01

    @@ Introduction Evaluation in TESOL settings is a process of collecting,analysing and interpreting information about teaching and learning in order to make informed decisions that enhance student achievement and the success of educational programmes (Rea-Dickins and Germaine 1993; Genesee and Upshur 1996;O'Malley and Valdez-Pierce 1996).Three simple examples help explicate the varied forms evaluation can take in TESOL settings:

  18. A multilevel analysis of key forms of community- and individual-level social capital as predictors of self-rated health in the United States.

    Science.gov (United States)

    Kim, Daniel; Kawachi, Ichiro

    2006-09-01

    Communities may be rich or poor in a variety of stocks of social capital. Studies that have investigated relations among these forms and their simultaneous and combined health effects are sparse. Using data on a sample of 24,835 adults (more than half of whom resided in core urban areas) nested within 40 U.S. communities from the Social Capital Benchmark Survey, correlational and factor analyses were applied to determine appropriate groupings among eight key social capital indicators (social trust, informal social interactions, formal group involvement, religious group involvement, giving and volunteering, diversity of friendship networks, electoral political participation, and non-electoral political participation) at each of the community and individual levels. Multilevel logistic regression models were estimated to analyze the associations between the grouped social capital forms and individual self-rated health. Adjusting the three identified community-level social capital groupings/scales for one another and community- and individual-level sociodemographic and socioeconomic characteristics, each of the odds ratios of fair/poor health associated with living in a community one standard deviation higher in the respective social capital form was modestly below one. Being high on all three (vs. none of the) scales was significantly associated with 18% lower odds of fair/poor health (odds ratio = 0.82, 95% confidence interval = 0.69-0.98). Adding individual-level social capital variables to the model attenuated two of the three community-level social capital associations, with a few of the former characteristics appearing to be moderately significantly protective of health. We further observed several significant interactions between community-level social capital and one's proximity to core urban areas, individual-level race/ethnicity, gender, and social capital. Overall, our results suggest primarily beneficial yet modest health effects of key summary forms of

  19. Aged human bone marrow stromal cells maintaining bone forming capacity in vivo evaluated using an improved method of visualization

    DEFF Research Database (Denmark)

    Stenderup, Karin; Rosada, Cecilia; Justesen, J;

    2004-01-01

    an in vivo assay for quantifying the bone forming capacity (BFC) and we compared the BFC of osteoblastic cells obtained from young and old donors. Osteoblasts were obtained from human bone marrow stromal cell cultures and implanted subcutaneously in immuno-deficient mice (NOD/LtSz- Prkdc(scid)). After 8...... weeks, the implants were removed and embedded un-decalcified in methyl methacrylate (MMA). Sections were stained histochemically with Goldner's Trichrome stain and immuno-histochemically using human-specific antibodies against known osteogenic markers. Implanted human marrow stromal cells (hMSC) were...... able to form bone in vivo. The donor origin of bone was verified using several human-specific antibodies. Dose-response experiments demonstrated that 5 x 10(5) hMSC per implant gave the maximal bone formation after 8 weeks. No difference in BFC was observed between cells obtained from young (24...

  20. Optical methods for the evaluation of film-forming ability of UPEC on the surface of medical devices

    Science.gov (United States)

    Al-Bayati, Basim M.; Nechaeva, Olga V.; Ulyanov, Vladimir Yu.; Glinskaya, Elena V.; Zayarsky, Dmitry A.; Tikhomirova, Elena I.; Vakaraeva, Malika M.; Bespalova, Natalia V.; Egorova, Anna V.

    2017-03-01

    The current study was designed to investigate the dynamics of microbial biofilm-formation in standard and clinical strains of uropathogenic Escherichia coli (UPEC), using spectrophotometric and electron microscopic methods. For achieving this goal, three E. coli strains were used (one standard and two clinical). These isolates differ in the existence of fimH virulence gene. The process involved the using of electron microscopy and immunological microtitration plates under in vitro conditions for 96 hours. We found that standard and clinical strains of E. coli were capable of forming a microbial biofilm in vitro, with a higher intensity related to the clinical strain E. coli 245. The using of scanning electron microscopy confirmed the obtained results. The combined use of different optical methods gives a complete characterization of film-forming ability of pathogenic microorganisms.