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Sample records for understood zingraff leiter

  1. Slow-Learner Student, Verbal and Nonverbal Intelligence, Wechsler, Leiter, Goodenough

    Directory of Open Access Journals (Sweden)

    Mahdieh-Sadat Khoshou'ei

    2014-04-01

    Full Text Available Objective: This research has been conducted with the aim of examining the performance of slow-learner first grade elementary students in Wechsler, Laiter and Goodenough Intelligence scales. Materials & Methods: The present study was a comparative study. The statistical population was consisted of slow-learner students who were studying in the 1st grade in elementary schools in Isfahan 50 students (25 girls, 25 boys were selected randomly. The Wechsler Intelligence Scale for Children-Revised, Leiter international performance scale and the Goodenough Draw-a-man test were used to measure verbal and nonverbal intelligences of students. Data were analyzed by using Pearson’s correlation coefficient and independent t-test. Results: the results showed that slow-learner students in Wechsler and Leiter scales had subscales were similar function. A significant correlation was found between the Leiter score with Wechsler (P<0.05 and with Goodenough (P0.05. Conclusion: the relationship between Leiter scale with Wechsler and Goodenough scales confirms the correctness of present assessment. Slow-learner boy and girl students of 1st grade in elementary school had the same performance on three intelligence scales.

  2. Christian Enichlmayr, Leiter der Oberösterreichischen Landesbibliothek von 1999 bis 2015, beantwortet 10 Fragen von Bruno Bauer

    Directory of Open Access Journals (Sweden)

    Christian Enichlmayr

    2016-05-01

    Full Text Available Christian Enichlmayr beantwortet Fragen über seinen Start ins Berufsleben in der Verlagsbranche, seine Zeit an der Universitätsbibliothek Linz und seinen Wechsel an die Oberösterreichische Landesbibliothek. 1999 bis 2015 war er als deren Leiter auch in führender Position für die Transformation der Bundesstaatlichen Studienbibliothek zur Landesbibliothek sowie die Sanierung und Erweiterung des Bibliotheksgebäudes verantwortlich. Weitere Themen, die in den vergangenen 17 Jahren an der Landesbibliothek stark forciert wurden, erstrecken sich von der NS-Provenienzforschung über die Entwicklung der digitalen Landesbibliothek bis zur Stärkung der Rolle der Landesbibliothek im oberösterreichischen Kulturleben. Zuletzt spricht Enichlmayr über die Bedeutung von Kooperationen im Bibliothekswesen, die Ausrichtung des Bibliothekartages der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare 2004 in Linz sowie die Perspektive für Bibliotheken.

  3. Poorly Understood Aspects of Striated Muscle Contraction

    Directory of Open Access Journals (Sweden)

    Alf Månsson

    2015-01-01

    Full Text Available Muscle contraction results from cyclic interactions between the contractile proteins myosin and actin, driven by the turnover of adenosine triphosphate (ATP. Despite intense studies, several molecular events in the contraction process are poorly understood, including the relationship between force-generation and phosphate-release in the ATP-turnover. Different aspects of the force-generating transition are reflected in the changes in tension development by muscle cells, myofibrils and single molecules upon changes in temperature, altered phosphate concentration, or length perturbations. It has been notoriously difficult to explain all these events within a given theoretical framework and to unequivocally correlate observed events with the atomic structures of the myosin motor. Other incompletely understood issues include the role of the two heads of myosin II and structural changes in the actin filaments as well as the importance of the three-dimensional order. We here review these issues in relation to controversies regarding basic physiological properties of striated muscle. We also briefly consider actomyosin mutation effects in cardiac and skeletal muscle function and the possibility to treat these defects by drugs.

  4. Burnout Study of Clinical Nurses in Vietnam: Development of Job Burnout Model Based on Leiter and Maslach's Theory.

    Science.gov (United States)

    Nguyen, Huong Thi Thu; Kitaoka, Kazuyo; Sukigara, Masune; Thai, Anh Lan

    2018-03-01

    This study aimed to create a Vietnamese version of both the Maslach Burnout Inventory-General Survey (MBI-GS) and Areas of Worklife Scale (AWS) to assess the burnout state of Vietnamese clinical nurses and to develop a causal model of burnout of clinical nurses. We conducted a descriptive design using a cross-sectional survey. The questionnaire was hand divided directly by nursing departments to 500 clinical nurses in three hospitals. Vietnamese MBI-GS and AWS were then examined for reliability and validity. We used the revised exhaustion +1 burnout classification to access burnout state. We performed path analysis to develop a Vietnamese causal model based on the original model by Leiter and Maslach's theory. We found that both scales were reliable and valid for assessing burnout. Among nurse participants, the percentage of severe burnout was 0.7% and burnout was 15.8%, and 17.2% of nurses were exhausted. The best predictor of burnout was "on-duty work schedule" that clinical nurses have to work for 24 hours. In the causal model, we also found similarity and difference pathways in comparison with the original model. Vietnamese MBI-GS and AWS were applicable to research on occupational stress. Nearly one-fifth of Vietnamese clinical nurses were working in burnout state. The causal model suggested a range of factors resulting in burnout, and it is necessary to consider the specific solution to prevent burnout problem. Copyright © 2018. Published by Elsevier B.V.

  5. How Self-Reliance Is Understood: Viewpoints from One Local ...

    African Journals Online (AJOL)

    DrNneka

    Tanzania's 1967 policy of self-reliance (Hultin 1985, p.8). Before looking at the way self-reliance is understood in rural Malawi during a process of development, it may be beneficial to look at some of the tensions between micro and macro forms of development. Leading to Self-Reliance. Development Aid is a term that has ...

  6. How self-reliance is understood: viewpoints from one local ...

    African Journals Online (AJOL)

    How self-reliance is understood: viewpoints from one local community in Malawi. ... model that resists dependence on external aid, empowers community development, and provides opportunities to sustain development activity through local initiative, can be employed to increase social capital leading to sustainable growth.

  7. Urachal tumour: case report of a poorly understood carcinoma

    Directory of Open Access Journals (Sweden)

    Vallarino Luigi

    2009-11-01

    Full Text Available Abstract Background Urachal carcinoma is an uncommon neoplasm associated with poor prognosis. Case presentation A 45-year-old man was admitted with complaints of abdominal pain and pollakisuria. A soft mass was palpable under his navel. TC-scan revealed a 11 × 6 cm tumor, which was composed of a cystic lesion arising from the urachus and a solid mass component at the urinary bladder dome. The tumor was removed surgically. Histological examination detected poor-differentiated adenocarcinoma, which had invaded the urinary bladder. The patient has been followed up without recurrence for 6 months. Conclusion The urachus is the embryological remnant of urogenital sinus and allantois. Involution usually happens before birth and urachus is present as a median umbilical ligament. The pathogenesis of urachal tumours is not fully understood. Surgery is the treatment of choice and role of adjuvant treatment is not clearly understood.

  8. Donors in Semiconductors - are they Understood in Electronic Era?

    International Nuclear Information System (INIS)

    Dmochowski, Janusz E

    2007-01-01

    The physics of semiconductors and contemporary electronics cannot be understood without impurities. The hydrogen-like shallow donor (and acceptor) state of electron (hole) bound by Coulomb electrostatic force of excess charge of impurity is used to control conductivity of semiconductors and construct semiconductor diodes, transistors and numerous types of semiconductor electronic and optoelectronic devices, including lasers. Recently, surprisingly, the physics of impurity donors appeared to be much reacher. Experimental evidence has been provided for universal existence of other types of electronic states of the same donor impurity: i) mysterious, deep, DX-type state resulting in metastability - slow hysteresis phenomena - understood as two-electron, acceptor-like state of donor impurity, formed upon large lattice distortion or rearrangement around impurity and accompanying capture of second electron, resulting in negative electron correlation energy U; ii) deep, localized, fully symmetric, A1, one-electron donor state of substitutional impurity. The latter state can be formed from the 'ordinary' shallow hydrogen-like state in the process of strong localization of electron by short range, local potential of impurity core, preserving full (A 1 ) symmetry of the substitutional impurity in the host lattice. The 'anticrossing' of the two A 1 (shallow hydrogenic and deep localized) energy levels upon transformation is observed. All types of electronic states of impurity can be universally observed for the same donor impurity and mutual transformation between different states occur upon changing experimental conditions. The knowledge about existence and properties of these n ew , molecular type, donor states in semiconductors seems still await general recognition and positive application in contemporary material and device science and engineering

  9. How operating room efficiency is understood in a surgical team: a qualitative study.

    Science.gov (United States)

    Arakelian, Erebouni; Gunningberg, Lena; Larsson, Jan

    2011-02-01

    Building surgical teams is one attempt to ensure the health-care system becomes more efficient, but how is 'efficiency' understood or interpreted? The aim was to study how organized surgical team members and their leaders understood operating room efficiency. Qualitative study. A 1100-bed Swedish university hospital. Eleven participants, nine team members from the same team and their two leaders were interviewed. The analysis was performed according to phenomenography, a research approach that aims to discover variations in peoples' understanding of a phenomenon. Seven ways of understanding operating room efficiency were identified: doing one's best from one's prerequisites, enjoying work and adjusting it to the situation, interacting group performing parallel tasks, working with minimal resources to produce desired results, fast work with preserved quality, long-term effects for patient care and a relative concept. When talking about the quality and benefits of delivered care, most team members invoked the patient as the central focus. Despite seven ways of understanding efficiency between the team members, they described their team as efficient. The nurses and assistant nurses were involved in the production and discussed working in a timely manner more than the leaders. The seven ways of understanding operating room efficiency appear to represent both organization-oriented and individual-oriented understanding of that concept in surgical teams. The patient is in focus and efficiency is understood as maintaining quality of care and measuring benefits of care for the patients.

  10. Congenital Vomer Agenesis: A Rare and Poorly Understood Condition Revealed by Cone Beam CT.

    Science.gov (United States)

    Yan, David Jun; Lenoir, Vincent; Chatelain, Sibylle; Stefanelli, Salvatore; Becker, Minerva

    2018-02-10

    Isolated congenital vomer agenesis is a very rare and poorly understood condition. In the context of dental work-up by cone-beam computed tomography (CBCT), the explored volume of the facial bones occasionally reveals incidental abnormalities. We report the case of a 13-year old Caucasian female who underwent CBCT for the pre-treatment evaluation of primary failure of tooth eruption affecting the permanent right upper and inferior molars. CBCT depicted a large defect of the postero-inferior part of the nasal septum without associated soft tissue abnormality and without cranio-facial malformation or cleft palate. In the absence of a history of trauma, chronic inflammatory sinonasal disease, neoplasia and drug abuse, a posterior nasal septum defect warrants the diagnosis of vomer agenesis. A discussion of this condition and of salient CBCT features is provided.

  11. Poorly understood and often miscategorized congenital umbilical cord hernia: an alternative repair method.

    Science.gov (United States)

    İnce, E; Temiz, A; Ezer, S S; Gezer, H Ö; Hiçsönmez, A

    2017-06-01

    Umbilical cord hernia is poorly understood and often miscategorized as "omphalocele minor". Careless clamping of the cord leads to iatrogenic gut injury in the situation of umbilical cord hernia. This study aimed to determine the characteristics and outcomes of umbilical cord hernias. We also highlight an alternative repair method for umbilical cord hernias. We recorded 15 cases of umbilical cord hernias over 10 years. The patients' data were retrospectively reviewed, and preoperative preparation of the newborn, gestational age, birth weight, other associated malformations, surgical technique used, enteral nutrition, and length of hospitalization were recorded. This study included 15 neonates with umbilical cord hernias. The mean gestational age at the time of referral was 38.2 ± 2.1 umbilical cord hernia, the body folds develop normally and form the umbilical ring. The double purse-string technique is easy to apply and produces satisfactory cosmetic results in neonates with umbilical cord hernias.

  12. Testing biochemistry revisited: how in vivo metabolism can be understood from in vitro enzyme kinetics.

    Directory of Open Access Journals (Sweden)

    Karen van Eunen

    Full Text Available A decade ago, a team of biochemists including two of us, modeled yeast glycolysis and showed that one of the most studied biochemical pathways could not be quite understood in terms of the kinetic properties of the constituent enzymes as measured in cell extract. Moreover, when the same model was later applied to different experimental steady-state conditions, it often exhibited unrestrained metabolite accumulation.Here we resolve this issue by showing that the results of such ab initio modeling are improved substantially by (i including appropriate allosteric regulation and (ii measuring the enzyme kinetic parameters under conditions that resemble the intracellular environment. The following modifications proved crucial: (i implementation of allosteric regulation of hexokinase and pyruvate kinase, (ii implementation of V(max values measured under conditions that resembled the yeast cytosol, and (iii redetermination of the kinetic parameters of glyceraldehyde-3-phosphate dehydrogenase under physiological conditions.Model predictions and experiments were compared under five different conditions of yeast growth and starvation. When either the original model was used (which lacked important allosteric regulation, or the enzyme parameters were measured under conditions that were, as usual, optimal for high enzyme activity, fructose 1,6-bisphosphate and some other glycolytic intermediates tended to accumulate to unrealistically high concentrations. Combining all adjustments yielded an accurate correspondence between model and experiments for all five steady-state and dynamic conditions. This enhances our understanding of in vivo metabolism in terms of in vitro biochemistry.

  13. The market of human organs: a window into a poorly understood global business.

    Science.gov (United States)

    Surman, O S; Saidi, R; Purtilo, R; Simmerling, M; Ko, D; Burke, T F

    2008-03-01

    The global demand for human organs has set the stage for an exploding and poorly understood global business in human organs. Whenever there is demand for a product, the opportunity for business arises. The form that a business takes is dependent on a complex network of inputs and outputs, each affecting the others. Historically, the details of any specific market are drastically underestimated. Nowhere is this truer than in the market of human organs. The drivers, which propel the "goods" of human organs, form a flourishing business. Critical analysis is essential to understanding of the supply and demand sides and to determine the role of government in regulating the industry. Governmental groups have dismissed formation of a regulated market for organ sales. The concept is nonetheless a topic of active discussion, motivated by the suffering of patients in need of organs and exploitation of the victims of human trafficking. Ethical principles have been invoked on each side of the ensuing debate. Theory in the absence of sufficient data is shaky ground for enactment of new policy. The Aristotelian concept of "practical wisdom" and the pragmatism of William James illuminate the importance of scientific investigation as guide to policy formation. How will stakeholders benefit or lose? What impact might be anticipated in regard to organized medicine's social contract? What can we learn about cross-cultural differences and their effect on the global landscape?

  14. How spirituality is understood and taught in New Zealand medical schools.

    Science.gov (United States)

    Lambie, D; Egan, R; Walker, S; MacLeod, R

    2015-02-01

    The objective of this research was to explore how spirituality is currently understood and taught in New Zealand Medical Schools. A mixed methods study was carried out involving interviews (n = 14) and a survey (n = 73). The first stage of the study involved recorded semi-structured interviews of people involved in curriculum development from the Dunedin School of Medicine (n = 14); which then informed a cross-sectional self-reported electronic survey (n = 73). The results indicate that spirituality is regarded by many involved in medical education in New Zealand as an important part of healthcare that may be taught in medical schools, but also that there is little consensus among this group as to what the topic is about. These findings provide a basis for further discussion about including spirituality in medical curricula, and in particular indicate a need to develop a shared understanding of what 'spirituality' means and how it can be taught appropriately. As a highly secular country, these New Zealand findings are significant for medical education in other secular Western countries. Addressing spirituality with patients has been shown to positively impact a range of health outcomes, but how spirituality is taught in medical schools is still developing across the globe.

  15. The vulnerability of family caregivers in relation to vulnerability as understood by nurses.

    Science.gov (United States)

    Sarvimäki, Anneli; Stenbock-Hult, Bettina; Sundell, Eija; Oesch-Börman, Christine

    2017-03-01

    In Finland, the care of older persons is shifting from institutional care to family care. Research shows that family caregivers experience their situation much in the same way as professional nurses. The nurses' experiences have been studied in terms of vulnerability, and the same perspective could deepen our understanding of family caregivers' experiences. The aim of this study was to gain knowledge of the vulnerability of older caregivers taking care of an ageing family member. The research questions were as follows: How do family caregivers experience vulnerability? How do their experiences relate to vulnerability as understood by nurses? The study was done as a secondary analysis of focus group interviews on the experiences and daily life of older family caregivers. Four caregivers had taken part in monthly interviews during a period of 10 months. The interviews were analysed by deductive and inductive content analysis. The results showed that the caregivers saw caregiving as part of being human. They experienced a variety of feelings and moral agony and were harmed physically, mentally and socially. They showed courage, protected themselves and recognised that being a caregiver also was a source of maturing and developing. These results corresponded with the nurses' understanding of vulnerability. Shame, the experience of duty as a burden, worry and loneliness were themes that were found only among the family caregivers. The use of a matrix may have restricted the analysis, but using it in an unconstrained way allowed for new themes to be created. The results indicate a common humanness and vulnerability in professional and family caregiving. They also show that family caregivers need more support both from society and professionals. © 2016 Nordic College of Caring Science.

  16. How Global Education Is Understood and to What Extent It Is Implemented in One Educator Preparation Program

    Science.gov (United States)

    Amewu-Sirleaf, Lydia Valentina

    2015-01-01

    This mixed method study investigated the overarching question "how global education is understood and implemented in an educator preparation program in a Colorado university". The sub-questions used to answer the research question are: (1) How is global education/perspective understood and implemented by the faculty; (2) How do students…

  17. Is restlessness best understood as a process? Reflecting on four boys’ restlessness during music therapy in kindergarten

    Science.gov (United States)

    Helle-Valle, Anna; Binder, Per-Einar; Anderssen, Norman; Stige, Brynjulf

    2017-01-01

    ABSTRACT ADHD can be considered an internationally recognized framework for understanding children’s restlessness. In this context, children’s restlessness is understood as a symptom of neurodevelopmental disorder. However, there are other possible understandings of children’s restlessness. In this article, we explore four boys’ collaborative and creative process as it is described and understood by three adults. The process is framed by a community music therapy project in a Norwegian kindergarten, and we describe four interrelated phases of this process: Exploring musical vitality and cooperation, Consolidating positions, Performing together, and Discovering ripple effects. We discuss these results in relation to seven qualities central to a community music therapy approach: participation, resource orientation, ecology, performance, activism, reflexivity and ethics. We argue that in contrast to a diagnostic approach that entails a focus on individual problems, a community music therapy approach can shed light on adult and systemic contributions to children’s restlessness. PMID:28532331

  18. African American Males in Foster Care and the Risk of Delinquency: The Value of Social Bonds and Permanence

    Science.gov (United States)

    Ryan, Joseph P.; Testa, Mark F.; Zhai, Fuhua

    2008-01-01

    Juvenile delinquency remains a significant problem for child welfare systems throughout the United States. Victims of child abuse and neglect are more likely relative to children in the general population to engage in delinquency (Ryan & Testa, 2005; Widom, 1989). Although the magnitude of this relationship is not fully understood (Zingraff,…

  19. Surgeon-level reporting presented by funnel plot is understood by doctors but inaccurately interpreted by members of the public.

    Science.gov (United States)

    Bhalla, Ashish; Mehrotra, Prerna; Amawi, Falah; Lund, Jonathan N

    2015-01-01

    Risk-adjusted outcome data for general surgeons practicing in the United Kingdom were published for the first time in 2013 with the aim of increasing transparency, improving standards, and providing the public with information to aid decision making. Most specialties used funnel plots to present their data. We assess the ability of members of the public (MoP), medical students, nonsurgical doctors (NSD), and surgeons to understand risk-adjusted surgical outcome data. A fictitious outcome dataset was created and presented in the form of a funnel plot to 10 participants from each of the aforementioned group. Standard explanatory text was provided. Each participant was given 5 minutes to review the funnel plot and complete a questionnaire. For each question, there was only 1 correct answer. Completion rate was 100% (n = 40). No difference existed between NSD and surgeons. A significant difference for identification of the "worst performing surgeon" was noted between surgeons and MoP (p funnel plot significantly "more difficult" to interpret than surgeons did (p < 0.01) and NSD (p < 0.01). MoP found these data significantly more "difficult to understand" and were less likely to both spot "outliers" and use this data to inform decisions than doctors. Surgeons should be aware that outcome data may require an alternative method of presentation to be understood by MoP. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  20. Conflict Prevalence in Primary School and How It Is Understood to Affect Teaching and Learning in Ghana

    Directory of Open Access Journals (Sweden)

    Nana Afia Amponsaa Opoku-Asare

    2015-07-01

    Full Text Available Verbal and non-verbal interactions that occur daily between teachers and headteachers, teachers and pupils, and among pupils can generate conflict that may adversely affect teaching, learning, and schooling effectiveness. Little attention is, however, paid to the quality of relationships that exists between teachers and pupils, among teachers, among pupils, between teachers and their school heads, and between schools and their local communities. This study sought to investigate conflict prevalence in Ghana’s primary schools, and how relationship conflict is understood to affect teaching and learning at the level of headteachers as administrators, teachers as classroom managers, and pupils as learners, and direct beneficiaries of primary education. Using data gathered via interview, questionnaire administration, and observation in 30 public primary schools in 10 circuits of one district of Ashanti Region, the findings revealed a high prevalence of fighting, heckling, bullying, and other forms of relationship conflict among pupils; strained teacher–pupil relations due to insolence, indiscipline, and use of offensive language; and teacher–parent arguments and quarrels due to harsh punishment and verbal assault of pupils. Teacher–pupil conflicts may extend to teachers excluding the affected pupils from teaching and learning activities, denying them the rights to ask and answer questions, and have their class exercises marked, leading to lowered pupil self-esteem, reduced concentration during lessons, and passive involvement in learning activities, which could result in truancy and school dropout. Strengthening guidance mechanisms and encouraging peer mediation could significantly curb conflict in school environments and thereby raise educational standards in the district.

  1. Home is to be understood

    DEFF Research Database (Denmark)

    Buhl, Mie; Werner Hansen, Siv

    2018-01-01

    situation in Denmark is, as in many other countries at the moment, complex. On the one hand laws and regulations are concurrently tightened concerning residency permits, boarder control, and possession of belongings. On the other hand a nationwide humanitarian (non-political) network of citizens who have...... engages with the current societal issue of migration by instigating a co-creation experiment, which aims to convert the museum’s vision (defined by values such as ‘community’, ‘participation’, ‘responsibility’ and ‘change’) into practice. In particular, we address how the museum creates a space...... and visual ethnography (Pink, 2013; Rose, 2012) from the process of initiating and planning of the project and including visual material from the launch of the exhibition. References: Bishop, C. (2006). The Social turn: Collaboration and Its Discontents, Artforum http...

  2. How flares can be understood

    International Nuclear Information System (INIS)

    Severny, A.B.

    1977-01-01

    Specific features of the flare phenomenon which are important for understanding of flares are the following: (1) Fine structure of visible emission of flares, especially at the very beginning and in the pre-flare active region. This structure can be seen also in later stages of development as bright points, some of which exist from the flare beginning (Babin's observations at Crimea, 1972-1976). (2) Turbulent motion with velocities up to 250-300 km s -1 as can be estimated from broadening of emission lines. (3) Predominantly red asymmetry of emission lines in the explosive phase and during further development of flares. (4) 'Supersonic' velocities and supergravitational accelerations of separate moving masses of the flare plasma. (5) The appearance of flares in areas with high grad H, exceeding 0.1 G km -1 which is equivalent to regions of electric currents > approximately 10 11 A. (6) Strong variations of net magnetic flux through the active region, as it follows from Meudon, Crimean, and Sacramento Peak (Rust's) observations. (Auth.)

  3. Can delusions be understood linguistically?

    Science.gov (United States)

    Hinzen, Wolfram; Rosselló, Joana; McKenna, Peter

    2016-01-01

    ABSTRACT Delusions are widely believed to reflect disturbed cognitive function, but the nature of this remains elusive. The “un-Cartesian” cognitive-linguistic hypothesis maintains (a) that there is no thought separate from language, that is, there is no distinct mental space removed from language where “thinking” takes place; and (b) that a somewhat broadened concept of grammar is responsible for bestowing meaning on propositions, and this among other things gives them their quality of being true or false. It is argued that a loss of propositional meaning explains why delusions are false, impossible and sometimes fantastic. A closely related abnormality, failure of linguistic embedding, can additionally account for why delusions are held with fixed conviction and are not adequately justified by the patient. The un-Cartesian linguistic approach to delusions has points of contact with Frith’s theory that inability to form meta-representations underlies a range of schizophrenic symptoms. It may also be relevant to the nature of the “second factor” in monothematic delusions in neurological disease. Finally, it can inform the current debate about whether or not delusions really are beliefs. PMID:27322493

  4. We Have Not Understood Descartes.

    Science.gov (United States)

    Vallias, Andras

    1996-01-01

    Describes a personal involvement with digital media and the origins of the conception of the "diagrammatic" poem. Reflects on what is considered to be a poem in tune with today's computerized society. (PA)

  5. Yes Virginia, quantum mechanics can be understood

    CERN Document Server

    Wallace, John P

    2017-01-01

    Virginia, B. W. Wooster, and Jeeves take up physics with the hope of understanding quantum mechanics. In the process they take a rather grand tour on an old sailing ship and aid a sow in distress. On their journey they discover that physics is not as difficult a subject as they imagined. When they dismantled physics and reassembled it in a form where gravity, strong, electromagnetic and the weak forces all stem from understanding the gaming strategy known as the fair-game. That great cultural divide first expounded by the novelist C.P.Snow was found to be a mere ditch that can be stepped over. The sins of the past were violations of energy conservation and strange notions about what mass actually represents. Now mass is defined without the assistance of the Standard Model. Things will not be the same. Singularities have been banished. The electron now has a scale and is no longer captive in a point. The gluon is no longer essential along with the single virtual photon.

  6. The Center of Gravity, Systemically Understood

    Science.gov (United States)

    2013-05-23

    Swain and Larry G. Heysteck (Riyadh, Saudi Arabia: CMH , Desert Storm Interviews, 1991), 33. 91Purvis, et al., 17. 40...Sullivan. "Interview: Centcom Planning Cell." In Unedited Transcript, edited by Richard Swain and Larry G. Heysteck. Riyadh, Saudi Arabia: CMH

  7. Evil Understood as the Absence of Freedom

    DEFF Research Database (Denmark)

    Rabjerg, Bjørn

    2017-01-01

    Self-development is closely related to the idea of formation (or what is referred to as Bildung in German). But when speaking of formation, we have to address the question, ‘what are we formed by?’ Is the human being formed by him- or herself, or by resources originating from outside the self? Fr...

  8. Visions of technology: : Big data lessons understood by EU policy makers in their review of the legal frameworks on intellectual property rights, access to and re-use of PSI and the protection of personal data

    NARCIS (Netherlands)

    Lammerant, Hans; de Hert, Paul; Gutwirth, Serge; Leenes, Ronald; De Hert, Paul

    2016-01-01

    This article’s focus is on how the advent of big data technology and practices has been understood and addressed by policy makers in the EU. We start with a reflection on of how big data affects business processes and how it con- tributes to the creation of a data economy. Then we look at EU policy

  9. Well Researched, Yet Little Understood: Young Adults and Physical Activity

    Science.gov (United States)

    Cothran, Donetta; Kulinna, Pamela Hodges

    2005-01-01

    The authors present two beginning studies. One investigated the teaching-style preferences of young adults, and the other looked at physical activity trends within this age group. One key to understanding young adults and physical activity is to recognize the importance of participant cognition on physical activity patterns. From this…

  10. Emotions are understood from biological motion across remote cultures.

    Science.gov (United States)

    Parkinson, Carolyn; Walker, Trent T; Memmi, Sarah; Wheatley, Thalia

    2017-04-01

    Patterns of bodily movement can be used to signal a wide variety of information, including emotional states. Are these signals reliant on culturally learned cues or are they intelligible across individuals lacking exposure to a common culture? To find out, we traveled to a remote Kreung village in Ratanakiri, Cambodia. First, we recorded Kreung portrayals of 5 emotions through bodily movement. These videos were later shown to American participants, who matched the videos with appropriate emotional labels with above chance accuracy (Study 1). The Kreung also viewed Western point-light displays of emotions. After each display, they were asked to either freely describe what was being expressed (Study 2) or choose from 5 predetermined response options (Study 3). Across these studies, Kreung participants recognized Western point-light displays of anger, fear, happiness, sadness, and pride with above chance accuracy. Kreung raters were not above chance in deciphering an American point-light display depicting love, suggesting that recognizing love may rely, at least in part, on culturally specific cues or modalities other than bodily movement. In addition, multidimensional scaling of the patterns of nonverbal behavior associated with each emotion in each culture suggested that similar patterns of nonverbal behavior are used to convey the same emotions across cultures. The considerable cross-cultural intelligibility observed across these studies suggests that the communication of emotion through movement is largely shaped by aspects of physiology and the environment shared by all humans, irrespective of differences in cultural context. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Prevalence of Obesity: A Public Health Problem Poorly Understood

    Directory of Open Access Journals (Sweden)

    Theresa A. Nicklas

    2014-06-01

    Full Text Available This review article discusses the Dietary Guidelines for Americans (DGA in support of a total diet approach to achieving diet and health goals, especially as they relate to the obesity epidemic. However, some scientists and organizations have identified one food, food group, or nutrient as the cause of the obesity epidemic and recommend that simply reducing that food/food group/nutrient will solve the problem. This is simplistic and unlikely to be effective in long term management of the obesity problem. This article also acknowledges discrepancies in the literature and the lack of consensus opinions from systematic reviews. Failure to consider the evidence as a whole can lead to inaccurate reports which may, in turn, adversely influence clinical practice, public policy, and future research. This article also considers where the line should be drawn between individual choice and responsibility and public regulation. Using sugar sweetened beverages as an example, the article considers the lack of a consistent association between added sugars and weight in the literature and calls for policy recommendations that are based on science and emphasizes the need for evidence-based policies rather than policy-based evidence.

  12. The bare parameters of Gribov's Langrangian are understood and determined

    International Nuclear Information System (INIS)

    Bishari, M.

    1977-01-01

    In the context of the ''1/N Dual Unitarization'' scheme, an explicit dynamical study of the triple bare pomeron mechanism which governs the interaction term in Gribov's Lagrangian is presented. Together with the previously established bare pomeron slope and intercept, controlling respectively, the kinetic and mass terms in Gribov's Lagrangian, this work demonstrates the viability of the ''1/N Dual Unitarization'' approach for a field theory of interaction bare pomerons. (author)

  13. Can morphogenesis be understood in terms of physical rules?

    Indian Academy of Sciences (India)

    Unknown

    In a similar way, 3D structures of bio- logical systems constructed by computer can serve as a data base which can be applied to research, education and practical purposes. 2.1 Construction of human lung airway. The lung airway is constructed within the amniotic fluid by branching of a duct. Since it does not touch other tis-.

  14. Happiness in Economics as Understood Across Ism and Religion

    Directory of Open Access Journals (Sweden)

    Abdul Ghafar Ismail

    2014-12-01

    Full Text Available The concept of happiness has been discussed long time ago by economists. Recently, it became the most related and important thing to be studied because of its impact in societies. Discussion about happiness basically interprets within two separate views. First, happiness related with economic variable, for instance, how money can create happiness. Second happiness is discussed within the context of religion. However, the discussion did not combine both contexts, economic variable and religion, to interpret happiness. Therefore, it is important to highlight the concept of happiness in a different way such as in this article. Different cultures will have their own perspective on the determination of happiness. From just “individual perspective” of happiness, they then formed an ism through involvement of a big society from the same culture. Some isms such as hedonism and materialism are synonyms in characterizing the concept of happiness in this modern world. At the same time, the isms are actually working with the economic and non-economic indicators as elements to strengthen the ism itself. On the other hand, the concept of happiness from the perspective of religion will also be a part of discussion in this article. Therefore, this article will reveal that the meaning of happiness is different in terms of religion and ism. So, to carry out both ism and religion simultaneously in shaping a more intrinsic value of happiness is not an easy task. Furthermore, religion is always associated with spiritual value that makes it hard for some people to practice religion and their isms at the same time. Thus, this article will propose that the right interpretation of isms based on their faith in religion can contribute to the concept of genuine happiness.

  15. Mirror neurons and their function in cognitively understood empathy.

    Science.gov (United States)

    Corradini, Antonella; Antonietti, Alessandro

    2013-09-01

    The current renewal of interest in empathy is closely connected to the recent neurobiological discovery of mirror neurons. Although the concept of empathy has been widely deployed, we shall focus upon one main psychological function it serves: enabling us to understand other peoples' intentions. In this essay we will draw on neuroscientific, psychological, and philosophical literature in order to investigate the relationships between mirror neurons and empathy as to intention understanding. Firstly, it will be explored whether mirror neurons are the neural basis of our empathic capacities: a vast array of empirical results appears to confirm this hypothesis. Secondly, the higher level capacity of reenactive empathy will be examined and the question will be addressed whether philosophical analysis alone is able to provide a foundation for this more abstract level of empathy. The conclusion will be drawn that both empirical evidence and philosophical analysis can jointly contribute to the clarification of the concept of empathy. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. Sharing their stories helps young people to feel more understood.

    Science.gov (United States)

    Butler, Zoe

    2017-05-10

    My passion for improving mental health services started after a young woman I knew took her own life. She was part of a theatre group I volunteered for, and the distress experienced by fellow members prompted me to take action.

  17. Default options in the ICU: widely used but insufficiently understood

    Science.gov (United States)

    Hart, Joanna; Halpern, Scott D.

    2015-01-01

    Purpose of review Default options dramatically influence the behavior of decision makers and may serve as effective decision support tools in the ICU. Their use in medicine has increased in an effort to improve efficiency, reduce errors, and harness the potential of healthcare technology. Recent findings Defaults often fall short of their predicted influence when employed in critical care settings as quality improvement interventions. Investigations reporting the use of defaults are often limited by variations in the relative effect across sites. Preimplementation experiments and long-term monitoring studies are lacking. Summary Defaults in the ICU may help or harm patients and clinical efficiency depending on their format and use. When constructing and encountering defaults, providers should be aware of their powerful and complex influences on decision making. Additional evaluations of the appropriate creation of healthcare defaults and their resulting intended and unintended consequences are needed. PMID:25203352

  18. Q Fever: An Old but Still a Poorly Understood Disease

    Directory of Open Access Journals (Sweden)

    Hamidreza Honarmand

    2012-01-01

    Full Text Available Q fever is a bacterial infection affecting mainly the lungs, liver, and heart. It is found around the world and is caused by the bacteria Coxiella burnetii. The bacteria affects sheep, goats, cattle, dogs, cats, birds, rodents, and ticks. Infected animals shed this bacteria in birth products, feces, milk, and urine. Humans usually get Q fever by breathing in contaminated droplets released by infected animals and drinking raw milk. People at highest risk for this infection are farmers, laboratory workers, sheep and dairy workers, and veterinarians. Chronic Q fever develops in people who have been infected for more than 6 months. It usually takes about 20 days after exposure to the bacteria for symptoms to occur. Most cases are mild, yet some severe cases have been reported. Symptoms of acute Q fever may include: chest pain with breathing, cough, fever, headache, jaundice, muscle pains, and shortness of breath. Symptoms of chronic Q fever may include chills, fatigue, night sweats, prolonged fever, and shortness of breath. Q fever is diagnosed with a blood antibody test. The main treatment for the disease is with antibiotics. For acute Q fever, doxycycline is recommended. For chronic Q fever, a combination of doxycycline and hydroxychloroquine is often used long term. Complications are cirrhosis, hepatitis, encephalitis, endocarditis, pericarditis, myocarditis, interstitial pulmonary fibrosis, meningitis, and pneumonia. People at risk should always: carefully dispose of animal products that may be infected, disinfect any contaminated areas, and thoroughly wash their hands. Pasteurizing milk can also help prevent Q fever.

  19. How is evidence to be understood in modern coaching psychology?

    DEFF Research Database (Denmark)

    Spaten, Ole Michael; Løkken, Lillith Olesen

    2015-01-01

    The hunt for evidence in modern coaching psychology could be counter-productive, and possibly lead to a simplified approach to research, practice, searching for “definitive truths”. The article discuss a critical approach to evidence hierarchies, and the prevalent (medical) understanding of evide......The hunt for evidence in modern coaching psychology could be counter-productive, and possibly lead to a simplified approach to research, practice, searching for “definitive truths”. The article discuss a critical approach to evidence hierarchies, and the prevalent (medical) understanding...

  20. Learning Outcomes of 'Understanding Research' as understood by ...

    African Journals Online (AJOL)

    Simon Bhekumuzi

    criterion for DT use, Tapscott (1998) referred to current digital users as the Net Generation, and later Prensky. (2001) referred to them as Digital natives, implying that as they are born in the digital era, it predisposes them to learning via digital technologies. The normalisation of technology in the everyday life of learners ...

  1. How Inclusive Education Is Understood by Principals of Independent Schools

    Science.gov (United States)

    Gous, Jennifer Glenda; Eloff, Irma; Moen, Melanie Carmen

    2014-01-01

    Inclusive education has become a practice that has been adopted by many schools across the globe and most usually in first-world countries. As a whole-school system, it occurs less frequently in developing countries including South Africa which unlike many developing countries has a sound infrastructure and many excellent schools in both the state…

  2. Clinical governance; How been understood, what is needed? Nurses' perspective

    Directory of Open Access Journals (Sweden)

    Homayoun Sadeghi Bazargani

    2015-07-01

    Full Text Available Introduction: Clinical Governance (CG is an overarching concept, using organizational capacity, safeguards high standards of the health services and provides a safe care for patients.  The aim of this research was to study nurses’ perception about Clinical Governance. Materials and Methods: A qualitative study was done with Focus Group Discussions (FGD. Purposeful Sampling was used to select the objectives including 65 participants. Actually 7 FGD’s were held. Content analysis was used to extract the meaningful themes. Results:Nurses believed that patient centeredness and evidence based practice is the core of the CG concept. Also they mentioned that cultural change, staffs training, adequate financial and human resources are required to successfully implementation of CG in hospitals.  Conclusion: Spreading up a shared vision about CG and providing the required infrastructures in hospitals would be facilitate CG initiatives. Proper commitment of the managers and staff participation could lead an effective CG implementation.

  3. How to Talk about Media You Haven't Understood

    OpenAIRE

    Casilli, Antonio,

    2014-01-01

    The following text, featured in the special issue of the Journal of Visual Culture (vol. 13, n. 1, April 2014) celebrating the 50th anniversary of Marshall McLuhan's 'Understanding Media: The Extensions of Man' is based on the talk given by Antonio A. Casilli at the McLuhan centenary conference 'McLuhan 100 Then Now Next' (7-11 November 2011, University of Toronto).

  4. Can PEP-3 Provide a Cognitive Profile in Children with ASD? A Comparison between the Developmental Ages of PEP-3 and IQ of Leiter-R

    Science.gov (United States)

    De Giacomo, Andrea; Craig, Francesco; Cristella, Arcangelo; Terenzio, Vanessa; Buttiglione, Maura; Margari, Lucia

    2016-01-01

    Background: The assessment of the intelligence quotient (IQ) in children with autism spectrum disorder (ASD) is important to plan a detailed therapeutic-educative programme. The aim of the study was to evaluate the usefulness of the Psychoeducational Profile-third edition (PEP-3) to estimate the general cognitive development of children with ASD.…

  5. The way I understood it, it wasn’t meant to be understood – when 6th grade reads Franz Kafka

    DEFF Research Database (Denmark)

    Johansen, Martin Blok

    2017-01-01

    In recent years, literacy problematics and different concepts (Cooperative Learning, Learning Styles) have taken up much of the school’s literature teaching. It has pushed discussions of the professional content into the background. This article takes up the content discussion for renewed debate......, but now also with the aim of discussing the literary texts one can present to children in school. The research questions posed are: Which texts can justifiably be presented to children as part of teaching in school? What will happen if 10 to 12-year-old Danish school pupils are presented with classical...... starting point in three concepts rooted in theory, i.e. unpredictability, defamiliarization and entitlement, which are subsequently used to get to grips with the empirical part of the study. The article does not attempt to depict a hard-and-fast picture of all children being equally enthusiastic about...

  6. "The Way I Understood It, It Wasn't Meant to Be Understood"--When 6th Grade Reads Franz Kafka

    Science.gov (United States)

    Johansen, Martin Blok

    2017-01-01

    In recent years, literacy problematics and different concepts (Cooperative Learning, Learning Styles) have taken up much of the school's literature teaching. It has pushed discussions of the professional content into the background. This article takes up the content discussion for renewed debate, but now also with the aim of discussing the…

  7. Tolerance as Understood by Young Russian and German Volunteers in Social Work

    Science.gov (United States)

    Sikorskaia, L. E.

    2008-01-01

    In 2006 the author and her colleagues carried out the sociological survey "Tolerance in Volunteer Social Work." They sought to determine the attitudes that young Russian and German volunteers of social work have when it comes to tolerance as a concept, a trait of personality, a principle of life and activity. They studied the various…

  8. Silicon as Versatile Player in Plant and Human Biology: Overlooked and Poorly Understood.

    Science.gov (United States)

    Farooq, Muhammad Ansar; Dietz, Karl-Josef

    2015-01-01

    Silicon (Si) serves as bioactive beneficial element. Si is highly abundant in soil, and occurs ubiquitously in all organisms including plants and humans. During the last three decades, nutritional significance of Si for plant and human health has received increasing attention. Plant Si plays a pivotal role in growth and development, and this beneficial effect depends usually on accumulation in plant tissues, which are then protected from various forms of biotic and abiotic stresses. Likewise, human exposure to Si imparts health benefits and essentially occurs through plant-derived food products. Si bioavailability in human diet, e.g., strengthens bones and improves immune response, as well as neuronal and connective tissue health. Despite this empiric knowledge, the essentiality of Si still remains enigmatic. Thus the link between Si availability for plant development and its profound implication for human welfare should receive attention. This review aims to provide a broad perspective on Si as important element for plant and human nutrition and to define research fields for interdisciplinary research.

  9. Learning Outcomes as Understood by "Publishing Research" Facilitators at a South African University

    Science.gov (United States)

    Khoza, Simon Bheki

    2013-01-01

    This article draws on a case study of six facilitators who were teaching Publishing Research in 2011 at one of the universities in South Africa. Publishing Research was offered by two campuses of this institution. This article gives these facilitators a voice and also identifies and defines the intended, implemented and attained learning outcomes…

  10. Transformations of Chinese International Students Understood through a Sense of Wholeness

    Science.gov (United States)

    Wang, Yina

    2012-01-01

    This study aims to explore Chinese international students' academic and personal transformation under the influences of formal education in schools and informal education outside of the classroom. A qualitative inquiry using in-depth, semi-structured interviews was employed with eight senior undergraduate Chinese international students attending…

  11. Osteogenesis imperfecta: recent findings shed new light on this once well-understood condition.

    Science.gov (United States)

    Basel, Donald; Steiner, Robert D

    2009-06-01

    Osteogenesis imperfecta is a systemic heritable disorder of connective tissue whose cardinal manifestation is bone fragility. In approximately 90% of individuals with osteogenesis imperfecta, mutations in either of the genes encoding the pro-alpha1 or pro-alpha2 chains of type I collagen (COL1A1 or COL1A2) can be identified. Of those without collagen mutations, a number of them will have mutations involving the enzyme complex responsible for posttranslational hydroxylation of the position 3 proline residue of COL1A1. Two of the genes encoding proteins involved in that enzyme complex, LEPRE1 and cartilage-associated protein, when mutated have been shown to cause autosomal recessive osteogenesis imperfecta, which has a moderate to severe clinical phenotype, often indistinguishable from osteogenesis imperfecta types II or III. Mutations in COL1A1 or COL1A2 which result in an abnormal protein still capable of forming a triple helix cause a more severe phenotype than mutations that lead to decreased collagen production as a result of the dominant negative effect mediated by continuous protein turnover. The current standard of care includes a multidisciplinary approach with surgical intervention when necessary, proactive physiotherapy, and consideration for the use of bisphosphonates all in attempts to improve quality of life.

  12. Vitamin D Status and the Host Resistance to Infections: What It Is Currently (Not) Understood.

    Science.gov (United States)

    Lang, Pierre Olivier; Aspinall, Richard

    2017-05-01

    Vitamin D is increasingly thought to play a role in regulating immunity. This comprehensive review updates the current understanding regarding ways in which we believe that vitamin D regulates responsiveness of the immune system and how serum status modulates the host defense against pathogens. The literature was searched by using PubMed and Scopus with the following key words: vitamin D, immunity, innate and adaptive immunity, infectious disease, and vaccine response. Vitamin D deficiency remains a major public health concern worldwide. The overall body of evidence confirms that vitamin D plays an important role in modulating the immune response to infections. Epidemiologic studies suggest a clear association between vitamin D deficiency and susceptibility to various pathogens. However, translation of vitamin D use into the clinic as a means of controlling infections is fraught with methodologic and epidemiologic challenges. The recent discovery of alternative activation pathways, different active forms of vitamin D, and possible interaction with non-vitamin D receptors provide further complications to an already complex interaction between vitamin D and the immune system. Moreover, it has become apparent that the individual responsiveness to supplementation is more dynamic than presumed from the static assessment of 25-hydroxy vitamin D status. Furthermore, the epigenetic response at the level of the individual to environmental changes and lifestyle or health conditions provides greater variation than those resulting from vitamin D receptor polymorphisms. To understand the future of vitamin D with respect to clinical applications in the prevention and better control of infectious diseases, it is necessary to determine all aspects of vitamin D metabolism, as well as the mechanisms by which active forms interact with the immune system globally. For the most part, we are unable to identify tissue-specific applications of supplementation except for those subjects at high risk of osteomalacia and osteoporosis. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

  13. understood with the help of a theoretical framework. He was also ...

    Indian Academy of Sciences (India)

    Srimath

    expansion of the universe therefore is an example of the coming together of theoretical work and innovation in technology in the advancement of science. This year, we are celebrating the International Year of Astronomy. Four hundred years ago, in 1609, Galileo held his telescope to view the starry heavens, and changed ...

  14. "I Understood the Complexity within Diversity": Preparation for Partnership with Families in Early Childhood Settings

    Science.gov (United States)

    Hedges, Helen; Lee, Debora

    2010-01-01

    "Partnership between parents and teachers" is a taken-for-granted feature of the philosophy and practice of early childhood education. Yet, the literature suggests this rhetoric belies a more complex and problematic reality for teachers. Making connections with the families and communities they will serve may help teacher education…

  15. Possibly All of that and Then Some: Scalar Implicatures Are Understood in Two Steps

    Science.gov (United States)

    Tomlinson, John M., Jr.; Bailey, Todd M.; Bott, Lewis

    2013-01-01

    Scalar implicatures often incur a processing cost in sentence comprehension tasks. We used a novel mouse-tracking technique in a sentence verification paradigm to test different accounts of this effect. We compared a two-step account, in which people access a basic meaning and then enrich the basic meaning to form the scalar implicature, against a…

  16. understood with the help of a theoretical framework. He was also ...

    Indian Academy of Sciences (India)

    Srimath

    to avoid the effects of turbulence in the lower atmosphere. A set of telescopes were built atop Mount Wilson in the western coast of USA just before Hubble began his work. The discovery of the expansion of the universe therefore is an example of the coming together of theoretical work and innovation in technology in the.

  17. Non-Universal Usability? A Survey of How Usability Is Understood by Chinese and Danish Users

    DEFF Research Database (Denmark)

    Frandsen-Thorlacius, Olaf; Hornbæk, Kasper Anders Søren; Hertzum, Morten

    2009-01-01

    , who differ in how they understand and prioritize different aspects of usability. Chinese users appear to be more concerned with visual appearance, satisfaction, and fun than Danish users; Danish users prioritize effectiveness, efficiency, and lack of frustration higher than Chinese users. The results...... suggest that culture influences perceptions of usability. We discuss implications for usability research and for usability practice....

  18. Immigration and Linguistic Diversity: A New and Poorly Understood Situation for Catalan

    Science.gov (United States)

    Comellas-Casanova, Pere

    2016-01-01

    For decades Catalan, a language minoritized and endangered by the hegemony of other state languages, has been experimenting with a process of revitalization driven by social activism and political autonomy, which has been particularly strong in some of its historical regions. Recently, however, serious doubts about the success of this process have…

  19. Group Differences in IQ Are Best Understood as Environmental in Origin

    Science.gov (United States)

    Nisbett, Richard E.; Aronson, Joshua; Blair, Clancy; Dickens, William; Flynn, James; Halpern, Diane F.; Turkheimer, Eric

    2012-01-01

    Responds to the comments by J. P. Rushton (see record 2012-24333-012); M. A. Woodley and G. Meisenberg (see record 2012-24333-013); and J. D. Mayer, D. R. Caruso, A. T. Panter, and P. Salovey (see record 2012-24333-014) on the present authors' original article, "Intelligence: New findings and theoretical developments" (see record…

  20. Are the Greenhouse Gas Implications of New Residential Developments Understood Wrongly?

    Directory of Open Access Journals (Sweden)

    Seppo Junnila

    2012-08-01

    Full Text Available Built environment carbon reduction strategies materialize predominantly in city-level greenhouse gas (GHG management, where new residential development appears as one of the key instruments. However, city-level assessments are often incapable of producing data at a community or neighborhood level and thus they may heavily underestimate the emissions from new construction. This paper explores the implications of low-energy residential construction as an instrument of climate change mitigation in the built environment and demonstrates why city-level approaches easily fail to identify the significance of the emissions from construction. We employ a hybrid life cycle assessment (LCA approach to demonstrate that, when the temporal allocation of emissions from the construction and use phases is taken into account, construction phase emissions come to have a central role in finding effective GHG mitigation strategies—even when the emissions from all consumption activities during the use phase are included in the assessment. In fact, their role would seem to be so central that new residential construction cannot be utilized as an instrument of city carbon management, even over a relatively long period. While we analyze a case study from Finland, the analysis intends to highlight the situation throughout the globe.

  1. Content-Based Instruction Understood in Terms of Connectionism and Constructivism

    Science.gov (United States)

    Lain, Stephanie

    2016-01-01

    Despite the number of articles devoted to the topic of content-based instruction (CBI), little attempt has been made to link the claims for CBI to research in cognitive science. In this article, I review the CBI model of foreign language (FL) instruction in the context of its close alignment with two emergent frameworks in cognitive science:…

  2. The physics of magnetic resonance imaging: how well understood is it?

    International Nuclear Information System (INIS)

    Reynolds, S.E.

    2000-01-01

    Full text: Part of my work involves tutoring trainee radiologists on the physics of magnetic resonance imaging (MRI). I have observed that a full understanding of the physics involved with MRI, or nuclear magnetic resonance (NMR) to be more specific, seems to be beyond the hopes of many people working in the field. All diagnostic radiology textbooks that I have read touch very superficially on the physics of NMR and sometimes the explanations and models used are quite inaccurate and misleading. After further investigation, I found some very good coverage on the subject in chemistry texts. The physics of NMR is based on some very difficult quantum mechanical concepts. What I have managed to understand has been tremendously satisfying and has shed light on several conceptual difficulties which I initially struggled with. The physics of MRI is based on the motion of the hydrogen proton when subjected to an external magnetic field. Protons, which are positively charged particles, have an intrinsic spin and as a result, a magnetic field. A proton, when placed in an external magnetic field, undergoes several changes in its motion. The laws of quantum mechanics govern these changes. Diagnostic radiology textbook models describing the motion of a proton tend to be poor and inaccurate leading to confusion. For example, subatomic particles are subject to laws of quantum mechanics and are forbidden to align exactly with an applied magnetic field thus creating precession. Some textbooks make no attempt to explain this phenomenon whereas others attempt a superficial but inadequate quantum mechanical explanation. I am interested to canvas opinions from others involved in MRI as to difficulties they have encountered with the understanding of the physics of MRI and how they have been overcome. Copyright (2000) Australasian College of Physical Scientists and Engineers in Medicine

  3. Muslim fundamentalism: something to be understood or to be explained away?

    NARCIS (Netherlands)

    Bruinessen, M.M. van

    1995-01-01

    This article surveys various attempts to make sociological sense of the diverse Muslim movements often lumped together under the label of fundamentalism. Explanations of fundamentalism as a form of resistance to modernization or those reducing it to social and economic discontent may have some

  4. Educational Leadership in Australian Private VET Organisations: How Is It Understood and Enacted?

    Science.gov (United States)

    Simons, Michele; Harris, Roger

    2014-01-01

    Ongoing reform in vocational education and training (VET) has placed significant pressure on leaders in private training organisations in terms of striking an 'appropriate' balance between educational and business imperatives. This paper draws on data from 34 interviews with leaders from 16 private registered training organisations in Australia to…

  5. How static media is understood and used by high school science teachers

    Science.gov (United States)

    Hirata, Miguel

    The purpose of the present study is to explore the role of static media in textbooks, as defined by Mayer (2001) in the form of printed images and text, and how these media are viewed and used by high school science teachers. Textbooks appeared in the United States in the late 1800s, and since then pictorial aids have been used extensively in them to support the teacher's work in the classroom (Giordano, 2003). According to Woodward, Elliott, and Nagel (1988/2013) the research on textbooks prior to the 1970s doesn't present relevant work related to the curricular role and the quality and instructional design of textbooks. Since then there has been abundant research, specially on the use of visual images in textbooks that has been approached from: (a) the text/image ratio (Evans, Watson, & Willows, 1987; Levin & Mayer, 1993; Mayer, 1993; Woodward, 1993), and (b) the instructional effectiveness of images (Woodward, 1993). The theoretical framework for this study comes from multimedia learning (Mayer, 2001), information design (Pettersson, 2002), and visual literacy (Moore & Dwyer, 1994). Data was collected through in-depth interviews of three high school science teachers and the graphic analyses of three textbooks used by the interviewed teachers. The interview data were compared through an analytic model developed from the literature, and the graphic analyses were performed using Mayer's multimedia learning principles (Mayer, 2001) and the Graphic Analysis Protocol (GAP) (Slough & McTigue, 2013). The conclusions of this study are: (1) pictures are specially useful for teaching science because science is a difficult subject to teach, (2) due this difficulty, pictures are very important to make the class dynamic and avoid students distraction, (3) static and dynamic media when used together can be more effective, (4) some specific type of graphics were found in the science textbooks used by the participants, in this case they were naturalistic drawings, stylized drawings, scale diagram, flow chart - cycle, flow chart - sequence, and hybrids, no photographs were found, (5) graphics can be related not only to the general text but specifically to the captions, (6) the textbooks analyzed had a balanced proportion of text and graphics, and (7) to facilitate the text-graphics relationship the spatial contiguity of both elements is key to their semantic integration.

  6. Silicon as versatile player in plant and human biology: Overlooked and poorly understood

    Directory of Open Access Journals (Sweden)

    Muhammad Ansar Farooq

    2015-11-01

    Full Text Available Silicon (Si serves as bioactive beneficial element. Si is highly abundant in soil, and occurs ubiquitously in all organisms including plants and humans. During the last three decades, nutritional significance of Si for plant and human health has received increasing attention. Plant Si plays a pivotal role in growth and development, and this beneficial effect depends usually on accumulation in plant tissues, which are then protected from various forms of biotic and abiotic stresses. Likewise, human exposure to Si imparts health benefits and essentially occurs through plant-derived food products. Si bioavailability in human diet e.g. strengthens bones and improves immune response, as well as neuronal and connective tissue health. Despite this empiric knowledge, the essentiality of Si still remains enigmatic. Thus the link between Si availability for plant development and its profound implication for human welfare should receive attention. This review aims to provide a broad perspective on Si as important element for plant and human nutrition and to define research fields for interdisciplinary research.

  7. Taxonomy of some little-understood North American ants (Hymenoptera: Formicidae).

    Science.gov (United States)

    Shattuck, Steve; Cover, Stefan

    2016-10-12

    The North American ant fauna has a long and detailed taxonomic history, and the fauna is relatively well characterized compared with those of many other regions. The vast majority of taxon names are clearly defined, being treated as either valid or invalid (primarily junior synonyms). Because of this, though considerable revisionary work will be necessary in the future, specimens collected from this region may often be placed with reasonable confidence either to species, or in some cases, to species complexes even if the status of the specific taxa involved are uncertain.

  8. 75 FR 31438 - Notice of Agreements Filed

    Science.gov (United States)

    2010-06-03

    ... Lines Joint Service Agreement. Filing Party: Tara L. Leiter, Esq.; Blank Rome, LLP; Watergate; 600 New... Service Agreement. Filing Party: Tara L. Leiter, Esq.; Blank Rome, LLP; Watergate; 600 New Hampshire...

  9. Open Access Policy White Paper der Max Planck Gesellschaft für eine grundlegende Änderung des bestehenden Publikationssystems. 10 Fragen von Bruno Bauer an Ralf Schimmer, Stellvertretender Leiter der Max Planck Digital Library

    Directory of Open Access Journals (Sweden)

    Ralf Schimmer

    2015-01-01

    Full Text Available Ralf Schimmer beantwortet Fragen über die Positionierung der Max Planck Gesellschaft zu Open Access und spricht auch über Motive und Zeitpunkt der Veröffentlichung der programmatischen Schrift „Disrupting the subscription journals' business model for the necessary large-scale transformation to open access: A Max Planck Digital Library Open Access Policy White Paper”. Thematisiert werden auch die verschiedenen Wege und die Finanzierung von Open Access sowie die Frage nach der künftigen Aufgabe für Bibliotheken, wenn Open Access das klassische Modell der subskriptions- und lizenzbasierten Zeitschrift abgelöst hat.

  10. Conductors, semiconductors, superconductors. A compact introduction to history, development, and theory of solid-state physics. 2. ed.; Leiter, Halbleiter, Supraleiter. Eine kompakte Einfuehrung in Geschichte, Entwicklung und Theorie der Festkoerperphysik

    Energy Technology Data Exchange (ETDEWEB)

    Huebener, Rudolf [Tuebingen Univ. (Germany). Fakultaet fuer Mathematik und Physik

    2017-05-01

    The present book is a strongly revised and supplemented edition of the title: ''Kristalle: Spiefeld der Elektronen'', published scarcely ten years ago by the same author. Especially the physical contents are explained by the mathematically formulated foundations. The book appeals to students of natural sciences and especially of physics as well as to engineers as introduction to the wide field of solid-state physics, so to speak as motivating prestage to the established and very extensive textbooks. Beside the physical contents the book treats the important role of numerous important and often still very young scientists. By corresponding supplements in this book it is tried to present the fundamental developments in their wide environment.

  11. A study of how precursor key concepts for organic chemistry success are understood by general chemistry students

    Science.gov (United States)

    Meyer, Patrick Gerard

    This study examines college student understanding of key concepts that will support future organic chemistry success as determined by university instructors. During four one-hour individual interviews the sixteen subjects attempted to solve general chemistry problems. A think-aloud protocol was used along with a whiteboard where the students could draw and illustrate their ideas. The protocols for the interviews were adapted from the Covalent Structure and Bonding two-tiered multiple choice diagnostic instrument (Peterson, Treagust, & Garnett, 1989) and augmented by the Geometry and Polarity of Molecules single-tiered multiple choice instrument (Furio & Calatayud, 1996). The interviews were videotaped, transcribed, and coded for analysis to determine the subjects' understanding of the key ideas. The subjects displayed many misconceptions that were summarized into nine assertions about student conceptualization of chemistry. (1) Many students misunderstand the location and nature of intermolecular forces. (2) Some think electronegativity differences among atoms in a molecule are sufficient to make the molecule polar, regardless of spatial arrangement. (3) Most know that higher phase change temperatures imply stronger intermolecular attractions, but many do not understand the difference between covalent molecular and covalent network substances. (4) Many have difficulty deciding whether a molecule is polar or non-polar, often confusing bilateral symmetry with spatial symmetry in all three dimensions. (5) Many cannot reliably draw correct Lewis structures due to carelessness and overuse of flawed algorithms. (6) Many are confused by how electrons can both repel one other and facilitate bonding between atoms via orbitals---this seems oxymoronic to them. (7) Many cannot explain why the atoms of certain elements do not follow the octet rule and some believe the octet rule alone can determine the shape of a molecule. (8) Most do know that electronegativity and polarity are not adequate to determine the shape of a molecule---but some apply the VSEPR theory in incorrect ways. (9) Students do not reason significantly differently when working with various representations of molecules such as ball-and-stick models, molecular formulas, and Lewis structures. The study illuminated specific parts of the general chemistry curriculum that are particularly troublesome for students but necessary for their further achievement in chemistry. This information is important; it gives the discipline of chemistry education target areas to focus on for general chemistry pedagogical improvement efforts.

  12. Joint Interagency Task Force-South: The Best Known, Least Understood Interagency Success (INSS Strategic Perspectives, Number 5, June 2011)

    Science.gov (United States)

    2011-06-01

    GHANA MACEDONIA U N I T E D S T A T E S GALAPAGOS ISLANDS South Georgia CANARY ISLANDS A L E U T I A N I S L A N D S S V A L B A R D Z E M LYA F R...R U B O L I V I A PARAGUAY A R G E N T I N A URUGUAY CHILE FALKLAND/MALVINAS ISLANDS NEW ZEALAND FIJI G R E E N L A N D ICELAND NORWAY SWEDEN FINLAND...LAOS THAILAND CAMBODIA VIETNAM M A L A Y S I A BRUNEI PHILIPPINES TAIWAN I N D O N E S I A PAPUA NEW GUINEA SOLOMON ISLANDS FIJI VANUATU NEW CALEDONIA

  13. What is beautiful is good and more accurately understood. Physical attractiveness and accuracy in first impressions of personality.

    Science.gov (United States)

    Lorenzo, Genevieve L; Biesanz, Jeremy C; Human, Lauren J

    2010-12-01

    Beautiful people are seen more positively than others, but are they also seen more accurately? In a round-robin design in which previously unacquainted individuals met for 3 min, results were consistent with the "beautiful is good" stereotype: More physically attractive individuals were viewed with greater normative accuracy; that is, they were viewed more in line with the highly desirable normative profile. Notably, more physically attractive targets were viewed more in line with their unique self-reported personality traits, that is, with greater distinctive accuracy. Further analyses revealed that both positivity and accuracy were to some extent in the eye of the beholder: Perceivers' idiosyncratic impressions of a target's attractiveness were also positively related to the positivity and accuracy of impressions. Overall, people do judge a book by its cover, but a beautiful cover prompts a closer reading, leading more physically attractive people to be seen both more positively and more accurately.

  14. How is palliative care understood in the context of dementia? Results from a massive open online course.

    Science.gov (United States)

    McInerney, Fran; Doherty, Kathleen; Bindoff, Aidan; Robinson, Andrew; Vickers, James

    2017-11-01

    A palliative approach to the care of people with dementia has been advocated, albeit from an emergent evidence base. The person-centred philosophy of palliative care resonates with the often lengthy trajectory and heavy symptom burden of this terminal condition. To explore participants' understanding of the concept of palliative care in the context of dementia. The participant population took an online course in dementia. The participant population took a massive open online course on 'Understanding Dementia' and posted answers to the question: 'palliative care means …' We extracted these postings and analysed them via the dual methods of topic modelling analysis and thematic analysis. A total of 1330 participants from three recent iterations of the Understanding Dementia Massive Open Online Course consented to their posts being used. Participants included those caring formally or informally for someone living with dementia as well as those with a general interest in dementia Results: Participants were found to have a general awareness of palliative care, but saw it primarily as terminal care, focused around the event of death and specialist in nature. Comfort was equated with pain management only. Respondents rarely overtly linked palliative care to dementia. A general lack of palliative care literacy, particularly with respect to dementia, was demonstrated by participants. Implications for dementia care consumers seeking palliative care and support include recognition of the likely lack of awareness of the relevance of palliative care to dementia. Future research could access online participants more directly about their understandings/experiences of the relationship between palliative care and dementia.

  15. GLP-2: A POORLY UNDERSTOOD MEDIATOR ENROLLED IN VARIOUS BARIATRIC/METABOLIC SURGERY-RELATED PATHOPHYSIOLOGIC MECHANISMS.

    Science.gov (United States)

    Cazzo, Everton; Gestic, Martinho Antonio; Utrini, Murillo Pimentel; Chaim, Felipe David Mendonça; Geloneze, Bruno; Pareja, José Carlos; Chaim, Elinton Adami; Magro, Daniéla Oliveira

    2016-01-01

    Glucagon-like peptide-2 (GLP-2) is a gastrointestinal hormone whose effects are predominantly trophic on the intestinal mucosa. Critically evaluate the current literature on the influence of bariatric/metabolic surgery on the levels of GLP-2 and its potential clinical implications. s: Narrative review through online research on the databases Medline and Lilacs. There were six prospective human studies, two cross-sectional human studies, and three experimental animal studies selected. There is evidence demonstrating significant increase in the levels of GLP-2 following gastric bypass, Scopinaro operation, and sleeve gastrectomy. There are no differences between gastric bypass and sleeve gastrectomy in regards to the increase in the GLP-2 levels. There is no correlation between the postoperative levels of GLP-2 and the occurrence of adequate or insufficient postoperative weight loss. GLP-2 plays significant roles on the regulation of nutrient absorption, permeability of gut mucosa, control of bone resorption, and regulation of satiety. The overall impact of these effects potentially exerts a significant adaptive or compensatory effect within the context of varied bariatric surgical techniques. O peptídeo semelhante ao glucagon-2 (GLP-2) é hormônio gastrointestinal com efeitos predominantemente tróficos sobre a mucosa intestinal. Avaliar criticamente a literatura atual a respeito da cirurgia bariátrica/metabólica sobre os níveis de GLP-2 e suas potenciais implicações clínicas. Revisão narrativa realizada através de pesquisa on-line nas bases de dados Medline e LILACS. Foram selecionados seis estudos prospectivos em humanos, dois transversais em humanos e três experimentais em animais. Existem evidências demonstrando aumento significativo nos níveis de GLP-2 após o bypass gástrico, a operação de Scopinaro e a gastrectomia vertical. Não foram observadas diferenças entre o bypass gástrico e a gastrectomia vertical em relação ao aumento do GLP-2. Não há correlação entre os níveis de GLP-2 e a ocorrência de perda de peso pós-operatória adequada ou insuficiente. O GLP-2 desempenha importantes papel sobre a regulação da absorção de nutrientes, permeabilidade da mucosa intestinal, controle da reabsorção óssea e regulação da saciedade. O impacto combinado destes efeitos potencialmente exerce efeito adaptativo ou compensatório importante no contexto das diferentes técnicas bariátricas.

  16. The impact of the Quaternary glaciations on the Durmitor mountains (Montenegro) as understood from detailed geomorphological mapping

    Science.gov (United States)

    Frankl, Amaury; Annys, Klaas; Spalević, Velibor; Čurović, Milic; Borota, Dragan; Nyssen, Jan

    2014-05-01

    In the Balkans, few studies exist that highlight the impact of the Quaternary glaciations on the landscape. However, the impact of the Quaternary glaciations was important and the glacial imprint remains well preserved in the limestone massifs where karst hydrology prevails. This study presents a detailed geomorphological map at scale 1:10,000 that was prepared of the northeastern Durmitor mountains (2523 m a.s.l.) and the plateau Jezerska Površ (47 km², Dinaric Alps, Montenegro). Mapping occurred from an intensive fieldwork campaign and remote sensing analysis, and was finalized in a GIS environment. The basic components of the legend are (i) processes/genesis, (ii) materials, (iii) morphometry/morphography, (iv) hydrography, (v) vegetation and (vi) anthropogenic features, that are organized as a box-of-bricks type of legend (AGRG-system). The geomorphological setting of the area consists of Mesozoic limestones which were eroded physically by Quaternary glacial and periglacial activity and chemically during interglacials. Glacial deposits of three Middle to Late Pleistocene glacial phases exist on the plateau, only scarcely dissected by meltwater channels. In the mountains, Holocene glacier retreat left behind a series of well-preserved recessional moraines and a static glacier remains in the cirque head. The presented map serves as a valuable tool for Quaternary research in the Durmitor Mountains, and serves as an example on the interaction between glacial and karst processes. Keywords: Debeli Namet glacier, Dinaric Alps, Geographic Information System (GIS), Glacial landforms, Karst.

  17. Three-to Four-Year-Olds' Recognition That Symbols Have a Stable Meaning: Pictures Are Understood Before Written Words

    Science.gov (United States)

    Apperly, Ian. A.; Williams, Emily; Williams, Joelle

    2004-01-01

    In 4 experiments 120 three-to four-year-old non readers were asked the identity of a symbolic representation as it appeared with different objects. Consistent with Bialystok (2000), many children judged the identity of written words to vary according to the object with which they appeared but few made such errors with recognizable pictures.…

  18. Conflict Prevalence in Primary School and How It Is Understood to Affect Teaching and Learning in Ghana

    OpenAIRE

    Nana Afia Amponsaa Opoku-Asare; Harriet Takyi; Margaret Owusu-Mensah

    2015-01-01

    Verbal and non-verbal interactions that occur daily between teachers and headteachers, teachers and pupils, and among pupils can generate conflict that may adversely affect teaching, learning, and schooling effectiveness. Little attention is, however, paid to the quality of relationships that exists between teachers and pupils, among teachers, among pupils, between teachers and their school heads, and between schools a...

  19. GLP-2: A POORLY UNDERSTOOD MEDIATOR ENROLLED IN VARIOUS BARIATRIC/METABOLIC SURGERY-RELATED PATHOPHYSIOLOGIC MECHANISMS

    Science.gov (United States)

    CAZZO, Everton; GESTIC, Martinho Antonio; UTRINI, Murillo Pimentel; CHAIM, Felipe David Mendonça; GELONEZE, Bruno; PAREJA, José Carlos; CHAIM, Elinton Adami; MAGRO, Daniéla Oliveira

    2016-01-01

    ABSTRACT Introduction: Glucagon-like peptide-2 (GLP-2) is a gastrointestinal hormone whose effects are predominantly trophic on the intestinal mucosa. Aim: Critically evaluate the current literature on the influence of bariatric/metabolic surgery on the levels of GLP-2 and its potential clinical implications. Method s: Narrative review through online research on the databases Medline and Lilacs. There were six prospective human studies, two cross-sectional human studies, and three experimental animal studies selected. Results: There is evidence demonstrating significant increase in the levels of GLP-2 following gastric bypass, Scopinaro operation, and sleeve gastrectomy. There are no differences between gastric bypass and sleeve gastrectomy in regards to the increase in the GLP-2 levels. There is no correlation between the postoperative levels of GLP-2 and the occurrence of adequate or insufficient postoperative weight loss. Conclusion: GLP-2 plays significant roles on the regulation of nutrient absorption, permeability of gut mucosa, control of bone resorption, and regulation of satiety. The overall impact of these effects potentially exerts a significant adaptive or compensatory effect within the context of varied bariatric surgical techniques. PMID:28076485

  20. The shaping of healthy & organic school meal programs in three Danish municipalities can be understood as a proces of "translation" in actor networks

    DEFF Research Database (Denmark)

    He, Chen; Mikkelsen, Bent Egberg

    2009-01-01

    Promotion of healthy eating in some Danish public school settings has become a preferred option to counteract the growing rates of obesity among young people. The purpose of study was to explore how these Danish school meal programs are shaped in their local communities. The study analyses...... the actor-groups in three municipalities using an actor network theoretical framework. The "translation" proces of the actor network was utilized to unfold the infrastructure of the school food service space in the municipalities. The first stage is the statement of core problem in the research so...... that define actors in the shaping process of school meal programs and influences then together to achieve the aim. Then distributes and locks each actor into its proper group: municipality, school or food provision. Afterwards interaction and relationship among all actors in three groups is illustrated...

  1. "Plastic Pollution: Myths, Facts, and How You Can Help": Presenting a popular but poorly understood topic to broad and diverse audiences

    Science.gov (United States)

    Brandon, J. A.

    2016-02-01

    For my thesis research, I study marine debris, specifically in the North Pacific Subtropical Gyre, colloquially known as the Great Pacific Garbage Patch. Marine debris in general, and the Great Pacific Garbage Patch in particular, are marine pollution issues that have captured considerable public and media attention. Especially in the late 2000s, there were significantly more popular media articles about marine debris and the Great Pacific Garbage Patch than scientific journal articles. Due to this popular attention and lag in scientific publication, there are a lot of exaggerated facts and prevalent myths about marine debris in the public consciousness today. As a graduate student at the Scripps Institution of Oceanography, UCSD, I have been given many opportunities to speak to diverse audiences about marine debris. These groups vary in their base knowledge of the issue, from very knowledgeable, to unknowledgeable, to knowledgeable but misinformed about the issue. Over my three years in graduate school, building off a base presentation from a previous graduate student and techniques learned from the education department at Birch Aquarium, I have developed ways to correct some misinformation while not making the audience feel insulted. I correct misinformation while building up a correct base knowledge. This knowledge can be very depressing, as many modern scientific problems can be, but I end the presentation with ways in which the audience can feel empowered and can continue to educate themselves. Hopefully they leave with both knowledge and applicable lessons that they can implement into their lives.

  2. An exploration of how psychotic-like symptoms are experienced, endorsed, and understood from the National Latino and Asian American Study and National Survey of American Life.

    Science.gov (United States)

    Earl, Tara R; Fortuna, Lisa Roxanne; Gao, Shan; Williams, David R; Neighbors, Harold; Takeuchi, David; Alegría, Margarita

    2015-01-01

    . To examine racial-ethnic differences in the endorsement and attribution of psychotic-like symptoms in a nationally representative sample of African-Americans, Asians, Caribbean Blacks, and Latinos living in the USA. Data were drawn from a total of 979 respondents who endorsed psychotic-like symptoms as part of the National Latino and Asian American Study (NLAAS) and the National Survey of American Life (NSAL). We use a mixed qualitative and quantitative analytical approach to examine sociodemographic and ethnic variations in the prevalence and attributions of hallucinations and other psychotic-like symptoms in the NLAAS and NSAL. The lifetime presence of psychotic-like symptoms was assessed using the World Health Organization Composite International Diagnostic Interview (WMH-CIDI) psychotic symptom screener. We used logistic regression models to examine the probability of endorsing the four most frequently occurring thematic categories for psychotic-like experiences by race/ethnicity (n > 100). We used qualitative methods to explore common themes from participant responses to open ended questions on their attributions for psychotic-like symptoms. African-Americans were significantly less likely to endorse visual hallucinations compared to Caribbean Blacks (73.7% and 89.3%, p supernatural, ghosts/unidentified beings, death and dying, spirituality or religiosity, premonitions, familial and other. Respondents differed by race/ethnicity in the attributions given to psychotic like symptoms. Findings suggest that variations exist by race/ethnicity in both psychotic-like symptom endorsement and in self-reported attributions/understandings for these symptoms on a psychosis screening instrument. Ethnic/racial differences could result from culturally sanctioned beliefs and idioms of distress that deserve more attention in conducting culturally informed and responsive screening, assessment and treatment.

  3. "I Understood the Words but I Didn't Know What They Meant": Japanese Online MBA Students' Experiences of British Assessment Practices

    Science.gov (United States)

    Fenton-O'Creevy, Mark; van Mourik, Carien

    2016-01-01

    We report on a case study of high Japanese student failure rates in an online MBA programme. Drawing on interviews, and reviews of exam and assignment scripts we frame the problems faced by these students in terms of a "language as social practice" approach and highlight the students' failure to understand the specific language games…

  4. Etap Hotel Augsburg City with green technology. VRV heat recovery technology in low-budget hotels: 2-conductor and 3-conductor systems; Etap Hotel Augsburg City mit gruenen Extras. VRV-Technologie in Low-Budgets-Hotels in 2- und 3-Leiter Ausfuehrung

    Energy Technology Data Exchange (ETDEWEB)

    Graupensberger, Thomas; Huhn, Ole [Daikin Airconditioning Germany GmbH, Muenchen (Germany)

    2011-11-15

    Etap Hotel, the low-budget hotels of the Accor Group and the European leader in this segment, opened a new hotel in Augsburg city on 1 March 2010. the building was constructed according to ecological criteria and boasts state-of-the-art technology. The contribution presents details.

  5. NIH Research on Concussion and the Brain

    Science.gov (United States)

    ... Table of Contents Dr. Anne McKee is a pioneer in the study of athletes' brains and the ... recently gave the Joseph Leiter Lecture at the Medical Library Association's annual conference. Her topic was "Boxing, ...

  6. 76 FR 17653 - Notice of Agreements Filed

    Science.gov (United States)

    2011-03-30

    .... Leiter, Esq.; Blank Rome, LLP; Watergate; 600 New Hampshire Avenue NW.; Washington, DC 20037. Synopsis... International Lines (PTE) Ltd.; and Wan Hai Lines Ltd. Filing Party: Robert B. Yoshitomi, Esq.; Nixon Peabody...

  7. How Lafd Cert May Be Understood as a Smart Practice: How it is Pioneering a Transition to Whole Community Cert and How it Can Serve as the Template for Cert Programs Nationally

    Science.gov (United States)

    2017-01-10

    Instructors to Build a More Robust Training Cadre with a Broader Skill Set .........................................................69 LIST OF...emergency management: mitigation, preparedness, response, and recovery.16 Lichterman describes the components of CERT training as examples of soft ...protection skills . The lessons learned in Mexico City strongly indicated a need for a plan to train volunteers to help themselves and others as part

  8. Contaminación de los alimentos por virus: un problema de salud pública poco comprendido Viral contamination of food products: a poorly understood public health problem

    Directory of Open Access Journals (Sweden)

    Carlos K. B. Ferrari

    1998-06-01

    Full Text Available En todas partes del mundo han surgido epidemias de enfermedades transmitidas por los alimentos (ETA sobre las que no existe suficiente información para guiar las acciones de las instituciones de salud pública. El presente estudio se hizo con objeto de contribuir a la diseminación de información sobre esas enfermedades, sus agentes etiológicos y su epidemiología y control. Se utilizaron datos de 61 estudios, entre ellos revisiones, descripciones de brotes y sistematización de datos. De los resultados obtenidos se pudo concluir que hay un gran problema de subregistro y falta de datos sobre estas enfermedades en los diversos países, pero los virus constituyen la segunda causa más importante de ETA en los Estados Unidos de América. Dos agentes, el virus Norwalk y el de la hepatitis A, ocuparon el quinto y sexto lugares, respectivamente, entre las causas principales de ETA, aunque el primero ocupó el primer puesto en 1982 y el segundo lugar como causa principal de enfermedades de transmisión hídrica durante el período de 1986 a 1988. A pesar de la escasez de datos al respecto, los rotavirus, poliovirus, virus de la hepatitis E, astrovirus y pequeños virus gastroentéricos también tienen importancia como agentes de ETA. En el artículo se discute también la importancia de las zoonosis víricas, especialmente de las fiebres hemorrágicas transmitidas por excretas de roedores y las encefalitis víricas transmitidas por garrapatas (fiebre difásica de la leche. Asimismo se presenta la polémica sobre la enfermedad de las vacas locas y su posible transmisión por los alimentos, además de los cuidados alimentarios relacionados con el sida y otras infecciones víricas. Por último, se describen los procedimientos de prevención y control de las ETA víricas.Throughout the world there have been several epidemics of food-borne diseases (FBD about which there is lack of sufficient information for public health institutions to take appropriate measures. This study was conducted for the purpose of contributing to the dissemination of information on these diseases and their etiologic agents, epidemiology, and control. The study was based on data from 61 sources, including review articles, reports of outbreaks, and databases. Results reveal considerable underregistration and lack of data on FBD throughout the various countries, with viruses being the second most important cause of FBD in the United States of America. Two agents, Norwalk virus and hepatitis A virus, were the fifth and sixth most frequent causes, respectively, although the former was the single most frequent cause of FBD in 1982 and the second most frequent cause of water-borne diseases during the period from 1986 to 1988. Despite the scarcity of information on the problem, rotavirus, poliovirus, hepatitis E virus, astrovirus, and small gastroenteric viruses are also important causes of FBD. We also discuss the importance of viral zoonoses, especially hemorrhagic fevers transmitted by contact with rodent feces and tick-borne viral encephalitides (Lassa fever. There is discussion of the controversial mad cow disease and its potential transmission through food products, as well as of dietary aspects of the management of AIDS and other viral infections. Finally, measures for the prevention and control of FBD are described.

  9. KARTEZYEN DÜALİZM’İN ‘DEMİR KAFES’İ VE WEBER’İN ANLADIĞI İSLAM TOPLUMU / IRON CAGE OF “CARTESIAN DUALISM” AND THE ISLAMIC SOCIETY UNDERSTOOD BY WEBER

    Directory of Open Access Journals (Sweden)

    Ejder ULUTAŞ

    2016-06-01

    Full Text Available Bryan S. Turner, “Max Weber ve İslam” adlı eserinde Weber’in İslam’a ve İslam toplumlarına yaklaşırken kendi yorumcu sosyolojisinin ölçütlerine uymadığını belirtmektedir. Ona göre Weber’in İslam’a yönelik değerlendirmeleri Marx’ınkinden pek de farklı değildir. Turner, Weber’in doğuya özgü bir toplum modeli olarak tasarımladığı patrimonyalizm kuramına sık sık atıfta bulunmaktadır. Bu düşüncenin, Weber’in oryantalist bir ön yargıya derin bağlılığından kaynaklandığını düşünmektedir. Dolayısıyla bu yazıda, bilim felsefesinde kendisine büyük bir taraftar ve izleyici kitlesi ve geniş hacimli bir tartışma alanı açan Kartezyen felsefenin kısa bir açıklama ve tartışması yapılmaktadır. ‘Batı Aklı’nın düştüğü çıkmazların bir örneği üzerinde durulmaktadır. Weber’in bilim anlayışı hakkında bir değerlendirme yapılmaktadır. İslam toplumlarını incelerken, pozitivist paradigmanın pek de dışına çıkamadığını dile getiren Turner’in eseri üzerinden de bir tartışma yürütülmektedir. Weber’in de kapıldığı düşünülen bu düalizm açmazı ele alınmaktadır.

  10. Complement inhibition by Sarcoptes scabiei protects Streptococcus pyogenes - An in vitro study to unravel the molecular mechanisms behind the poorly understood predilection of S. pyogenes to infect mite-induced skin lesions.

    Science.gov (United States)

    Swe, Pearl M; Christian, Lindsay D; Lu, Hieng C; Sriprakash, Kadaba S; Fischer, Katja

    2017-03-01

    On a global scale scabies is one of the most common dermatological conditions, imposing a considerable economic burden on individuals, communities and health systems. There is substantial epidemiological evidence that in tropical regions scabies is often causing pyoderma and subsequently serious illness due to invasion by opportunistic bacteria. The health burden due to complicated scabies causing cellulitis, bacteraemia and sepsis, heart and kidney diseases in resource-poor communities is extreme. Co-infections of group A streptococcus (GAS) and scabies mites is a common phenomenon in the tropics. Both pathogens produce multiple complement inhibitors to overcome the host innate defence. We investigated the relative role of classical (CP), lectin (LP) and alternative pathways (AP) towards a pyodermic GAS isolate 88/30 in the presence of a scabies mite complement inhibitor, SMSB4. Opsonophagocytosis assays in fresh blood showed baseline immunity towards GAS. The role of innate immunity was investigated by deposition of the first complement components of each pathway, specifically C1q, FB and MBL from normal human serum on GAS. C1q deposition was the highest followed by FB deposition while MBL deposition was undetectable, suggesting that CP and AP may be mainly activated by GAS. We confirmed this result using sera depleted of either C1q or FB, and serum deficient in MBL. Recombinant SMSB4 was produced and purified from Pichia pastoris. SMSB4 reduced the baseline immunity against GAS by decreasing the formation of CP- and AP-C3 convertases, subsequently affecting opsonisation and the release of anaphylatoxin. Our results indicate that the complement-inhibitory function of SMSB4 promotes the survival of GAS in vitro and inferably in the microenvironment of the mite-infested skin. Understanding the tripartite interactions between host, parasite and microbial pathogens at a molecular level may serve as a basis to develop improved intervention strategies targeting scabies and associated bacterial infections.

  11. The relationship between the big five personality factors and burnout : A study among volunteer counselors

    NARCIS (Netherlands)

    Bakker, A.B.; Van der Zee, K.I.; Lewig, K.A.; Dollard, M.F.

    In the present study of 80 volunteer counselors who cared for terminally ill patients, the authors examined the relationship between burnout as measured by the Maslach Burnout Inventory (C. Maslach, S. E. Jackson, & M. P. Leiter, 1996) and the 5 basic (Big Five) personality factors (A. A. J.

  12. Sultan anno 1987

    International Nuclear Information System (INIS)

    Roeterdink, J.A.

    1987-01-01

    This article treats the state of affairs of the international SULTAN-project (SupraLeiter Test ANlage), in which ECN (Dutch Energy Research Foundation) collaborates with research institutes in Switzerland and Italy. The article is mainly concerned with the Dutch contribution in the domain of superconductors and superconducting magnet coils. (author). 7 refs.; 10 figs.; 2 tabs

  13. Burnout and Work Engagement: Independent Factors or Opposite Poles?

    Science.gov (United States)

    Gonzalez-Roma, Vicente; Schaufeli, Wilmar B.; Bakker, Arnold B.; Lloret, Susana

    2006-01-01

    Burnout researchers have proposed that the conceptual opposites of emotional exhaustion and cynicism (the core dimensions of burnout) are vigor and dedication (the core dimensions of engagement), respectively (Maslach & Leiter, 1997; Schaufeli, Salanova, Gonzalez-Roma, & Bakker, 2002). We tested this proposition by ascertaining whether two sets of…

  14. Too Stressed to Teach? Teaching Quality, Student Engagement, and IEP Outcomes

    Science.gov (United States)

    Wong, Venus W.; Ruble, Lisa A.; Yu, Yue; McGrew, John H.

    2017-01-01

    Teacher stress and burnout have a detrimental effect on the stability of the teaching workforce. However, the possible consequences of teacher burnout on teaching quality and on student learning outcomes are less clear, especially in special education settings. We applied Maslach and Leiter's (1999) model to understand the direct effects of…

  15. 77 FR 27227 - Notice of Agreements Filed

    Science.gov (United States)

    2012-05-09

    ... agreement. Agreement No.: 011275-032. Title: Australia and New Zealand-United States Discussion Agreement....G. Filing Party: Tara L. Leiter, Esquire; Blank Rome LLP; 600 New Hampshire Avenue NW., Washington... trade between the U.S. East Coast and China. Agreement No.: 012169. Title: Crowley/ELJSA Space Charter...

  16. Occupational Burnout and Retention of Air Force Distributed Common Ground System (DCGS) Intelligence Personnel

    Science.gov (United States)

    2012-01-01

    Leiter, 2001) emotional exhaustion “is the central quality of burnout and the most obvious manifestation of this complex syndrome .” Because...What job stress means for the staff nurse. Nursing Administration Quarterly, 7, 1-11. Allen, M. (2012, January). (J. Langley, Interviewer) Bacharach...and Burnout in Sexual Assault and Domestic Violence Agency Staff . Violence and Victims, 18(1), 71-86. Birck, A. (2001). Secondary traumatization

  17. Members of the German Federal Parliament Research Committee visiting ALICE experiment on Wednesday, 15th November.

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    From left to right Mr Georg Jürgens, Counsellor at the German Mission in Geneva; MdB Klaus Hagemann, SPD; MdB Cornelia Pieper, FDP, Stellvertretende Ausschussvorsitzende, Delegationsleiterin; MdB Dr. Petra Sitte, DIE LINKE; MdB Ilse Aigner, CDU/CSU; MdB Carsten Müller, CDU/CSU; Mr Andreas Meyer, Leiter Ausschusssekretariat; MdB Jörg Tauss, SPD.

  18. The validation of a workplace incivility scale within the South African banking industry

    OpenAIRE

    Olivia Smidt; Leon T. de Beer; Lizelle Brink; Michael P. Leiter

    2016-01-01

    Orientation: Workplace incivility holds consequences for both individuals and organisations. Managers are becoming increasingly aware of this phenomenon. Currently, there is no workplace incivility scale validated for use within the South African context. Research purpose: To investigate the reliability and validity of the adapted workplace incivility scale by Leiter and colleagues for use within South Africa. Motivation for the study: As it is currently difficult to measure workpl...

  19. ENFERMAGEM COMPREENDIDA COMO VOCAÇÃO E SUA RELAÇÃO COM AS ATITUDES DOS ENFERMEIROS FRENTE ÀS CONDIÇÕES DE TRABALHO ENFERMERÍA COMPRENDIDA COMO VOCACIÓN Y SU RELACIÓN CON LAS ACTITUDES DE LOS ENFERMEROS FRENTE A LAS CONDICIONES DE TRABAJO NURSING UNDERSTOOD AS A VOCATION AND ITS RELATIONS TO NURSES' ATTITUDES TOWARDS WORK CONDITIONS

    Directory of Open Access Journals (Sweden)

    Rosa Maria Rodrigues

    2001-11-01

    Full Text Available A proposta é refletir sobre a enfermagem enquanto trabalho, afastando sua concepção amplamente aceita que a identifica a uma atividade de ajuda, sendo que tal concepção poderia ser fator dificultante para o enfrentamento e transformação das condições de trabalho. Tenta situar na história o contexto em que é elaborado o modelo vocacional/religioso e identificar nas falas de alunos do primeiro e quarto ano de um curso de Graduação em Enfermagem as manifestações daquela concepção, apontando para a necessidade da atividade docente ser permeada pela concepção da enfermagem/trabalho.La propuesta es reflexionar sobre la enfermería como trabajo, alejando su concepción ampliamente aceptada. que la identifica como una actividad de ayuda, siendo que tal concepción podría ser un factor que dificulta el enfrentamiento y la transformación de las condiciones de trabajo. Él trabajo intenta situar en la historia el contexto en que es elaborado el modelo vocacional/religioso e identificar en los discursos de los alumnos de pregrado de enfermería las manifestaciones de aquella concepción, apuntando para la necesidad de la actividad docente estar influenciada por la concepción de la enfermería/trabajo.This study aimed at reflecting about nursing as job by disconsidering the widely accepted conception that identifies it as an assistance activity for that conception might hinder actions towards coping with and changing work conditions. The study attempted to place in history the context in which the vocational/religious model was elaborated as well as to identify the manifestations of that conception in the discourse of Nursing freshmen and seniors, pointing out the fact that the teaching activity must be permeated by the conception of nursing/work.

  20. Ökophysik: Plaudereien über das Leben auf dem Land, im Wasser und in der Luft

    Science.gov (United States)

    Nachtigall, W.

    Prof. em. Dr. rer. nat. Werner Nachtigall, geb. 1934, war als Zoophysiologe und Biophysiker Leiter des Zoologischen Instituts der Universität des Saarlandes in Saarbrücken. In Forschung und Ausbildung hat er sich insbesondere mit Aspekten der Technischen Biologie und Bionik befasst und mit seinen Forschergruppen viele Basisdaten insbesondere zur Ökologie, Physiologie und Physik des Fliegens und Schwimmens aber auch zur Stabilität beispielsweise der Gräser erarbeitet. Lebewesen überraschen immer wieder durch ihre "Biodiversität", ihre hochspezifischen Ausgestaltungen und Anpassungen.

  1. The evolutionary history of the mammalian synaptonemal complex

    OpenAIRE

    Fraune, Johanna

    2014-01-01

    Der Synaptonemalkomplex (SC) ist eine hochkonservierte Proteinstruktur. Er weist eine dreiteili-ge, leiterähnliche Organisation auf und ist für die stabile Paarung der homologen Chromosomen während der Prophase der ersten meiotischen Teilung verantwortlich, die auch als Synpase be-zeichnet wird. Fehler während der Synpase führen zu Aneuploidie oder Apoptose der sich entwi-ckelnden Keimzellen. Seit 1956 ist der SC Gegenstand intensiver Forschung. Seine Existenz wurde in zahlreichen Orga-nis...

  2. Cognitive and academic outcomes in long-term survivors of infantile-onset Pompe disease: A longitudinal follow-up.

    Science.gov (United States)

    Spiridigliozzi, Gail A; Keeling, Lori A; Stefanescu, Mihaela; Li, Cindy; Austin, Stephanie; Kishnani, Priya S

    2017-06-01

    This study examines the long-term cognitive and academic outcomes of 11 individuals with infantile onset Pompe disease (IOPD) (median age=11years, 1month, range=5years, 6months through 17years of age) treated with enzyme replacement therapy from an early age. All participants (7 males, 4 females) were administered individual intelligence tests (Wechsler or Leiter scales or both), a measure of their academic skill levels (Woodcock-Johnson Tests of Achievement), and a screening measure of visual-motor integration ability (Beery-Buktenica). Consistent with our earlier findings, median IQ scores for the entire group on the Wechsler (median=84) and Leiter (median=92) scales continue to fall at the lower end of the average range compared to same-aged peers. The median scores for the group on a measure of visual-motor integration (median=76), visual perception (median=74) and motor coordination (median=60) were below average. Two distinct subgroups emerged based on participants' average or below average performance on the majority of academic subtests. Those participants with below average academic skills (n=6) demonstrated average nonverbal cognitive abilities on the Leiter, but had weaknesses in speech and language skills and greater medical involvement. Their profiles were more consistent with a learning disability diagnosis than an intellectual disability. Two of these participants showed a significant decline (15 and 23 points, respectively) on repeated Wechsler scales, but one continued to earn average scores on the Leiter scales where the verbal and motor demands are minimal. Participants with average academic skills (n=5) demonstrated average cognitive abilities (verbal and nonverbal) on the Wechsler scales and less medical involvement. Their speech and language skills appeared to be more intact. However, both groups earned below average median scores on the Beery-Buktenica motor coordination task. This study highlights the importance of using appropriate tests to

  3. [The role of engineer Gustave Trouvé (1839-1902) in the history of endoscopy].

    Science.gov (United States)

    Ségal, A

    1995-01-01

    The author relates the important contribution of engineer Gustave Trouvé (1839-1902) in endoscopy's history. Since 1873, he was, in fact, the first to ... set an electric light at the tip of the endoscope, by using a small incandescent airtight bulb. Edison's "Mignon" bulb was only discovered after 1886. The Vienese manufacturer Joseph Leiter was completely absorbed with the importance of this invention without having mentioned the true value of this rises of information, in this case G. Trouvé and surely also Dr Max Nitze who was despoiled.

  4. Cognitive profile and activities of daily living

    DEFF Research Database (Denmark)

    Borgwardt, Line Gutte; Thuesen, A M; Olsen, K J

    2015-01-01

    BACKGROUND: Alpha-mannosidosis (OMIM 248500) (AM) is a rare lysosomal storage disease caused by a deficiency of the alpha-mannosidase enzyme. The typical signs consist of hearing impairment, intellectual disabilities, coarse facial features and motor function disturbances. We report on the cognit......BACKGROUND: Alpha-mannosidosis (OMIM 248500) (AM) is a rare lysosomal storage disease caused by a deficiency of the alpha-mannosidase enzyme. The typical signs consist of hearing impairment, intellectual disabilities, coarse facial features and motor function disturbances. We report...... on the cognitive function and activities of daily living in patients with AM. METHODS: Thirty five AM patients, age 6-35 years, were included in the study. As a cognitive function test, we used the Leiter international performance scale-revised (Leiter-R), which consists of two batteries: the visual function......) was significantly reduced, between 3-9 years old for the visual function and reasoning battery, between 2.3-10.2 years for the memory screening. Data suggested a specific developmental profile for AM with a positive intellectual development until the chronological age 10-12 years, followed by a static or slightly...

  5. Sweetness and light: perspectives for rodent models of type 1 diabetes.

    Science.gov (United States)

    Avner, Philip R

    2010-01-01

    Type 1 diabetes (T1D) is a major disease affecting primarily young children with an incidence in Western societies of around 0.3% by 20 years of age. Although both genetic and environmental factors contribute to the disease aetiology, the precise nature of both the genetic and environmental contribution to human disease onset and progression remains poorly defined. Despite showing some differences from human T1D, rodent models for T1D (Leiter and von Herrath, 2004; von Herrath and Nepom, 2009) and, in particular the nonobese diabetic (NOD) mouse (Atkinson and Leiter, 1999; Kikutani and Makino, 1992), have provided important insights into the disease process, even if they have not yet allowed definitive identification of many of the genetic factors involved in the process. The recent isolation of germline-competent embryonic stem (ES) cells from the NOD mouse strain, and from the rat, will greatly facilitate the functional analysis of T1D in the mouse, and open up the possibility of improved exploitation of rat T1D models. This important technological breakthrough has the potential to remove bottlenecks from the identification of T1D genes, allowing the underlying metabolic pathways to be established and facilitating evaluation of the eventual role of the human homologues in the disease process. The current status and perspectives for an improved mechanistic understanding of the disease process will be addressed.

  6. Comparison of African American Children's Performances on a Minimal Competence Core for Morphosyntax and the Index of Productive Syntax.

    Science.gov (United States)

    Stockman, Ida J; Newkirk-Turner, Brandi L; Swartzlander, Elaina; Morris, Lekeitha R

    2016-02-01

    This study is a response to the need for evidence-based measures of spontaneous oral language to assess African American children under the age of 4 years. We determined if pass/fail status on a minimal competence core for morphosyntax (MCC-MS) was more highly related to scores on the Index of Productive Syntax (IPSyn)-the measure of convergent criterion validity-than to scores on 3 measures of divergent validity: number of different words (Watkins, Kelly, Harbers, & Hollis, 1995), Percentage of Consonants Correct-Revised (Shriberg, Austin, Lewis, McSweeney, & Wilson, 1997), and the Leiter International Performance Scale-Revised (Roid & Miller, 1997). Archival language samples for 68 African American 3-year-olds were analyzed to determine MCC-MS pass/fail status and the scores on measures of convergent and divergent validity. Higher IPSyn scores were observed for 60 children who passed the MCC-MS than for 8 children who did not. A significant positive correlation, rpb = .73, between MCC-MS pass/fail status and IPSyn scores was observed. This coefficient was higher than MCC-MS correlations with measures of divergent validity: rpb = .13 (Leiter International Performance Scale-Revised), rpb = .42 (number of different words in 100 utterances), and rpb = .46 (Percentage of Consonants Correct-Revised). The MCC-MS has convergent criterion validity with the IPSyn. Although more research is warranted, both measures can be potentially used in oral language assessments of African American 3-year-olds.

  7. Standards for protection against electric shock; Errichtungsnormen fuer den Schutz gegen elektrischen Schlag

    Energy Technology Data Exchange (ETDEWEB)

    Biegelmeier, G. [Privatstiftung ' ' Elektroschutz' ' , Vienna (Austria); Spindler, U. [Moeller Holding GmbH und Co. KG, Bonn (Germany)

    2001-09-01

    An improved concept for protection against electric shock current is presented for discussion among IEC, CENELEC, and DKE. In particular, the loop resistance presents a practical way of defining simple shutoff conditions especially in systems with a PE conductor. Further, a low-voltage protection concept is presented which would make the VDE 0100 more user-friendly. [German] Der Aufsatz stellt ein verbessertes Konzept fuer den Schutz gegen elektrischen Schlag vor; damit sollen weitere Diskussionen innerhalb der IEC, CENELEC und der DKE angeregt werden. Im Besonderen wird darauf hingewiesen, dass duerch den Schleifenwiderstand eine praxisfreundliche Moglichkeit besteht, speziell fuer Anlagen, in denen ein PE-Leiter installiert ist, einfache Ausschaltbedingungen aufgrund von Ausschaltstromfaktoren festzulegen. Weiter wird ein geandertes Schutzkleinspannungskonzept vorgestellt. Damit koennte dem weltverbreiteten Wunsch nach einer anwenderfreundlicheren VDE 0100 Rechnung getragen werden. (orig.)

  8. Toward a model of employee engagement in a public service organization

    DEFF Research Database (Denmark)

    Nielsen, Mette Strange

    Employee engagement has long been capturing the attention of researchers and practitioners, (e.g. Bakker, Albrecht, & Leiter, 2011; Buckingham & Coffman, 1999) due to its positive impact on various measures of organizational performance (Gruman & Saks, 2011; Harter, Schmidt, & Hayes, 2002; Mone...... & London, 2010). To date, however, employee engagement has primarily been studied in private manufacturing firms leaving out a gap of research in a public service organization, such as eldercare organizations, although engagement according to Boselie (2010) is highly relevant in the specific context....... The purpose of the PhD project is to build a model explaining employee engagement in a public service organization. Research on work design theory (e.g. Hackman & Oldham, 1976) will be used, since it has often been applied to identify antecedents associated with engagement (Bakker & Demerouti, 2007; Kahn...

  9. Observing eye movements and the influence of cognition during a symbol search task: a comparison across three age groups.

    Science.gov (United States)

    Perrin, Maxine; Robillard, Manon; Roy-Charland, Annie

    2017-12-01

    This study examined eye movements during a visual search task as well as cognitive abilities within three age groups. The aim was to explore scanning patterns across symbol grids and to better understand the impact of symbol location in AAC displays on speed and accuracy of symbol selection. For the study, 60 students were asked to locate a series of symbols on 16 cell grids. The EyeLink 1000 was used to measure eye movements, accuracy, and response time. Accuracy was high across all cells. Participants had faster response times, longer fixations, and more frequent fixations on symbols located in the middle of the grid. Group comparisons revealed significant differences for accuracy and reaction times. The Leiter-R was used to evaluate cognitive abilities. Sustained attention and cognitive flexibility scores predicted the participants' reaction time and accuracy in symbol selection. Findings suggest that symbol location within AAC devices and individuals' cognitive abilities influence the speed and accuracy of retrieving symbols.

  10. Understanding employee engagement in a public service context

    DEFF Research Database (Denmark)

    Nielsen, Mette Strange

    Employee engagement has long been capturing the attention of researchers and practitioners (Bakker, Albrecht, & Leiter, 2011; Kahn, 1990), due to its positive impact on various measures of organizational performance and individual level outcomes (Gruman & Saks, 2011; Harter, Schmidt, & Hayes, 2002......). To date however, employee engagement has primarily been studied in private manufacturing firms, but since it cannot be assumed that employee engagement models developed in the private sector are applicable to the public sector (Boselie, 2010; Taher & Emmert, 1992), future research is needed. The purpose...... of this paper is therefore to build a research agenda aiming to understand employee engagement in a public service context. The paper begins with a literature review of the main contributions to the study of employee engagement and then follows with a brief review of the public sector, highlighting some...

  11. Reasoning Abilities and Potential Correlates Among Jordanian School Children.

    Science.gov (United States)

    Almomani, Fidaa; Al-Momani, Murad O; Alsheyab, Nihayah; Al Mhdawi, Khader

    2018-04-01

    Objectives To investigate factors related to reasoning skills in 434 school children aged 5-9 years. Methods The Leiter International Performance Scale-Revised was used to assess reasoning skills. Demographic, work and family income data, information on child's daily behavior and school academic achievement were provided by the participating children's parents. Results Reasoning scores increased by 4.56 points with increasing subject's age, 1.71 points with increasing level of father's occupation, 1.86 points with each increase in the subject's GPA, 1.13 points with consumption of breakfast at home and 1.81 points when child slept more hours. Having a father who smoked and living in a rural area decreased scores in reasoning. Conclusions for Practice Screening of reasoning and associated factors is essential for a comprehensive and accurate understanding of the child's abilities and limitations. Understanding the child's reasoning abilities is critical for establishing intervention goals and planning therapeutic activities.

  12. Motor competency and social communication skills in preschool children with autism spectrum disorder.

    Science.gov (United States)

    Craig, Francesco; Lorenzo, Alessandro; Lucarelli, Elisabetta; Russo, Luigi; Fanizza, Isabella; Trabacca, Antonio

    2018-03-01

    This study aimed to investigate the association between motor competency and social communication in children with Autism Spectrum Disorder (ASD) compared with children with Intellectual Disabilities (ID) and typically developing (TD) children. Motor competency, ASD symptoms, and nonverbal Intelligent Quotient (IQ) were investigated through the following tests: Movement Assessment Battery for Children, second edition (MABC-2), Social Communication Questionnaire (SCQ), Autism Classification System of Functioning: Social Communication (ACSF:SC) and Leiter International Performances Scale Revised (Leiter-R). The ASD + ID and ID groups had lower MABC-2-manual dexterity mean scores, MABC-2-aiming and catching mean scores, MABC-2-static and dynamic balance mean scores and MABC-2-TTS compared with the TD group (P < 0.05). In addition, the ASD + ID group had lower MABC-2-aiming and catching mean scores compared with the ID group. In the ASD + ID group, we found a significant negative correlation (P < 0.001) between MABC-2-aiming and catching scores with SCQ scores, nonverbal IQ and ACSF:SC levels. Our findings provide new insight into the common neuropsychological mechanisms underlying social communication and motor deficits in ASD. Multiple deficits in motor functioning may be present in ASD and ID, however deficits involving the ability to integrate motor and social cues are somewhat specific to ASD. Autism Res 2018. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. This study highlighted the specificity of motor impairment in ASD comparing performances on a frequently used measure of motor impairment between clinical groups (ASD + ID and ID) and a non-clinical group. While previous research has suggested that multiple deficits in motor functioning may be present in ASD, our findings suggest that deficits in tasks involving the ability to integrate visual and motor cues (aiming and catching task) are somewhat specific to

  13. Asperger syndrome in adolescent and young adult males. Interview, self- and parent assessment of social, emotional, and cognitive problems.

    Science.gov (United States)

    Cederlund, Mats; Hagberg, Bibbi; Gillberg, Christopher

    2010-01-01

    Descriptive and comparative follow-up studies of young adult males with Asperger syndrome (AS) diagnosed in childhood, using both interview, self- and parent assessment instruments for the study of aspects of emotional well-being, social functioning, and cognitive-practical skills have not been performed in the past. One-hundred males with AS diagnosed in childhood were approached for the assessment using the Asperger Syndrome Diagnostic Interview (ASDI), (personal and parent interview), the Leiter-R-Questionnaires, the Beck Depression Inventory (BDI), and the Dysexecutive Questionnaire (DEX). About 75% of the targeted group participated. The ASDI results came out significantly different at personal vs parent interviews in several key domains. In contrast, the Leiter-R-Questionnaires, showed no significant differences across the individuals with AS and their parents in the scoring of cognitive/social and emotional/adaptive skills. The BDI proved to be an adequate screening instrument for depression in that it correctly identified the vast majority of cases with clinical depression in the AS group. The DEX results suggested an executive function deficit problem profile in males with AS as severe as that reported in groups of individuals with traumatic brain injury and schizophrenia. Interviews (personal and collateral), and self-rating and parent-rating questionnaires all have a role in the comprehensive diagnostic process in AS and other autism spectrum disorders, and could be used as adjuncts when evaluating whether or not individuals meeting diagnostic symptom criteria for the condition have sufficient problems in daily life to warrant a clinical diagnosis of AS. Copyright 2009 Elsevier Ltd. All rights reserved.

  14. Object-related generativity in children with Down syndrome.

    Science.gov (United States)

    Fidler, Deborah J; Will, Elizabeth; Daunhauer, Lisa A; Gerlach-McDonald, Brianne; Visootsak, Jeannie

    2014-12-01

    Children with Down syndrome (DS) show challenges in some aspects of goal-directed behavior when compared to developmentally matched children (Daunhauer et al., 2014; Lee et al., 2011), particularly in the area of goal-directed action on objects (Fidler et al., 2005a,b). In this study, we examined one aspect of goal-directed action on objects, object-related generativity, in school-aged children with DS (n = 52), a developmentally matched group of children with intellectual disability, but not Down syndrome (DD; n = 21), and a group of chronologically younger, but developmentally matched typically developing children (TD; n = 34). We administered the Leiter-R, the Oral and Written Language Scales (OWLS), and an Object-Related Generativity Task, which involved 2 min of unstructured play with a variety of objects that have divergent usages. Children with DS generated significantly fewer instances of initiating actions on new objects than children in both comparison groups, were less likely to produce novel functional action on any object (new or familiar) than TD children, and they showed fewer instances of novel functional object engagement with new objects overall than TD children. Frequency of acts on new objects in DS was associated with Leiter-R Form Completion and Repeated Patterns Raw Scores and OWLS Listening Comprehension Raw Scores. These findings contribute to the growing knowledge base regarding goal-directed behavior and self-regulation in individuals with Down syndrome. Implications for education and intervention are discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Investigation of transient, mechanical disturbances in superconducting cables with internal cooling; Untersuchungen von transienten mechanischen Stoerungen in intern gekuehlten Supraleiterkabeln

    Energy Technology Data Exchange (ETDEWEB)

    Hertle, R.

    1994-01-01

    One of the major causes of early loss of superconductivity of cables in superconducting magnets are mechanical disturbances induced by Lorentz forces, the causes observed being frictional mechanisms, cracks, dislocations, and deformations. Although it is possible to estimate the threshold value of interfering energy up to which a superconductor will remain, stable, but it is not yet feasible to assess the defects dimensions prior to a coil test with the internally cooled, CIC wires. The report explains the development of a method which allows to determine, by way of a simple test with a piece of cable, the friction and deformation energy released in the CIC cable of a magnet during the phase of coil start up. For the test, short cable pireces of the castle to form the wiring of the magnet are used. Their stress-strain hysteresis curves are recorded at room temperature and LN{sub 2} temperature, under transverse compression. Also, the number or rate and intensity of the various frictional or deformation processes are recorded by means of acoustic emission analysis. By correlating measured data and events, conclusions can be drawn as to the mechanical energy released in every process. (MM) [Deutsch] Eine der Hauptursachen eines vorzeitigen Verlusts der Supraleitfaehigkeit von Kabeln in Supraleiter-Magneten sind durch Lorenzkraefte verusachte mechanische Stoerungen wie Reibungsvorgaenge, Risse, Spruenge und Verformungen. Es ist zwar moeglich, die Grenze abzuschaetzen, bis zu welcher Stoerenergie ein Supraleiter stabil ist, aber es ist bisher fuer intern gekuehlte CIC-Leiter (cable in conduit) nicht moeglich, die Groesse solcher Stoerungen vor einem Spulentest zu bestimmen. In dieser Arbeit wird eine Methode entwickelt mit Hilfe derer man in der Lage ist, die beim Hochfahren eines aus einem CIC-Leiter aufgebauten Magneten die im Kabel freiwerdende Reibungs- und Verformungsenergie durch einen einfachen Versuch an einem Kabelstueck schon vorher zu bestimmen. Dazu werden

  16. Burnout and Job Engagement in Emergency and Intensive Care Nurses

    Science.gov (United States)

    Argentero, Piergiorgio; Dell'Olivo, Bianca

    Burnout phenomenon emerges from a constellation of factors which cannot be described in terms of cause-effect relationships. This study investigated levels of burnout in nurses working in Critical Care Units with a systemic approach, giving evidence of relation between nurses staff burnout and psychosocial workplace factors. The purpose of this study was to examine the relationship between job burnout in emergency and intensive care nurse with specific areas of work life in their organizations, using Maslach and Leiter work life model [23]. A cross-sectional survey was designed using the Italian version of the "Organizational Checkup System" in a sample of 180 Italian nurses. Results showed that high burnout levels were strongly related to high demands, low control, low fairness, lack of social support, and individual disagreement on values in the workplace. High professional efficacy levels were instead correlated to professional reward and leadership involvement. The article concludes by suggesting the possible areas for intervention in order to prevent job burnout and building job engagement.

  17. Internal contamination: what challenges for tomorrow? Proceedings of the Research and Health Section technical day

    International Nuclear Information System (INIS)

    Berard, Philippe; Lecoix, Geraldine; Menetrier, Florence; Menetrier, Florence; Leiterer, Alexandra; Gremy, Olivier; Mougnard, Philippe; Gonin, Michele; Paquet, Francois; Davesne, Estelle; Bertho, Jean-Marc; Metivier, Henri; Abergel, Rebecca

    2015-10-01

    The Research and Health Section of the French Society of Radiation Protection (SFRP) organized a technical meeting on the radiation protection aspects of dismantlement, from the dismantling work to the risk, the measurement of body contamination, the potentially harmful health effects, the available medical treatments, the actual needs and the developments in progress. This document brings together the abstracts and the presentations (slides) of the different talks given at the meeting: 1 - Situation: what radionuclides, what situations? (Philippe BERARD, CEA); 2 - Dismantling workplace experience feedback with internal contamination hazard (Philippe MOUGNARD, AREVA); 3 - Experience feedback on internal exposure monitoring at power plants in France (Michele GONIN, EDF); 4 - Evolution of routine and intervention measurement methods (Geraldine LECOIX, CEA); 5 - Evolution of radiation dose calculation models (Francois PAQUET, IRSN); 6 - Taking uncertainties into account in internal contamination monitoring protocols (Estelle DAVESNE, IRSN); 7 - Radionuclides behaviour and effects in men (Florence MENETRIER, CEA); 8 - The plutonium case (Henri METIVIER, SFRP); 9 - Cesium-137 and internal contamination: status and perspectives (Jean-Marc BERTHO, IRSN); 10 - Iodine and thyroid (Florence MENETRIER, CEA); 11 - Actual treatments and research pathways (Alexandra LEITERER, CEA); 12 - Radionuclide contamination treatment: new developments in the US (Rebecca ABERGEL, Berkeley USA); 13 - Internal contaminations treatment: French recent effort for its improvement (Olivier GREMY, CEA)

  18. Educational and rehabilitation service utilization in adolescents born preterm or with a congenital heart defect and at high risk for disability.

    Science.gov (United States)

    Majnemer, Annette; Dahan-Oliel, Noemi; Rohlicek, Charles; Hatzigeorgiou, Sean; Mazer, Barbara; Maltais, Desiree B; Schmitz, Norbert

    2017-10-01

    This historical cohort study describes the use of educational and rehabilitation services in adolescents born preterm or with a congenital heart defect (CHD). Parents of 76 young people (mean age 15y 8mo [SD 1y 8mo]) with CHD and 125 born ≤29 weeks gestational age (mean age 16y [SD 2y 5mo]) completed a demographics questionnaire including educational and rehabilitation resource utilization within the previous 6 months. Rehabilitation services included occupational therapy, physical therapy, speech language pathology, psychology. Developmental (Leiter Brief IQ, Movement-ABC, Strengths and Difficulties Questionnaire) and functional (Vineland) status of the young people was assessed. Pearson χ 2 tests were used to perform simple pairwise comparisons of categorical outcomes across the two groups (CHD, preterm). Univariate logistic regression was used to examine predictors of service utilization. Developmental profiles of the two groups (CHD/preterm) were similar (29.9%/30% IQpeople with motor deficits were more likely to require educational (CHD: OR 5.72, 1.99-16.42; preterm: OR 3.11, 1.43-6.77) and rehabilitation services (preterm: OR 3.97, 1.21-13.03). Although young people with impairments were more likely to receive educational and rehabilitation services, many may not be adequately supported, particularly by rehabilitation specialists. Rehabilitation services at this important transition phase could be beneficial in optimizing adaptive functioning in the home, school, and community. © 2017 Mac Keith Press.

  19. Overlap Between Autism Spectrum Disorders and Attention Deficit Hyperactivity Disorder: Searching for Distinctive/Common Clinical Features.

    Science.gov (United States)

    Craig, Francesco; Lamanna, Anna Linda; Margari, Francesco; Matera, Emilia; Simone, Marta; Margari, Lucia

    2015-06-01

    Recent studies support several overlapping traits between autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD), assuming the existence of a combined phenotype. The aim of our study was to evaluate the common or distinctive clinical features between ASD and ADHD in order to identify possible different phenotypes that could have a clinical value. We enrolled 181 subjects divided into four diagnostic groups: ADHD group, ASD group, ASD+ADHD group (that met diagnostic criteria for both ASD and ADHD), and control group. Intelligent quotient (IQ), emotional and behavior problems, ADHD symptoms, ASD symptoms, and adaptive behaviors were investigated through the following test: Wechsler Intelligence Scale for Children, Wechsler Preschool and Primary Scale of Intelligence or Leiter International Performances Scale Revised, Child Behavior Checklist, Conners' Rating Scales-Revised, SNAP-IV Rating Scale, the Social Communication Questionnaire, Vineland Adaptive Behavior Scales. The ASD+ADHD group differs from ADHD or ASD in some domains such as lower IQ mean level and a higher autistic symptoms severity. However, the ASD+ADHD group shares inattention and hyperactivity deficit and some emotional and behavior problems with the ADHD group, while it shares adaptive behavior impairment with ASD group. These findings provide a new understanding of clinical manifestation of ASD+ADHD phenotype, they may also inform a novel treatment target. © 2015 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research.

  20. Emotional Dissonance and Burnout: The Moderating Role of Team Reflexivity and Re-Evaluation.

    Science.gov (United States)

    Andela, Marie; Truchot, Didier

    2017-08-01

    The aim of the present study was to better understand the relationship between emotional dissonance and burnout by exploring the buffering effects of re-evaluation and team reflexivity. The study was conducted with a sample of 445 nurses and healthcare assistants from a general hospital. Team reflexivity was evaluated with the validation of the French version of the team reflexivity scale (Facchin, Tschan, Gurtner, Cohen, & Dupuis, 2006). Burnout was measured with the MBI General Survey (Schaufeli, Leiter, Maslach, & Jackson, 1996). Emotional dissonance and re-evaluation were measured with the scale developed by Andela, Truchot, & Borteyrou (2015). With reference to Rimé's theoretical model (2009), we suggested that both dimensions of team reflexivity (task and social reflexivity) respond to both psychological necessities induced by dissonance (cognitive clarification and socio-affective necessities). Firstly, results indicated that emotional dissonance was related to burnout. Secondly, regression analysis confirmed the buffering role of re-evaluation and social reflexivity on the emotional exhaustion of emotional dissonance. Overall, results contribute to the literature by highlighting the moderating effect of re-evaluation and team reflexivity in analysing the relationship between emotional dissonance and burnout. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  1. Sustainability in agricultural machinery production - an empirical study among farmers

    Directory of Open Access Journals (Sweden)

    Yuliya Bezruk

    2014-04-01

    Full Text Available Um die Einstellungen von Landwirten hinsichtlich der Nachhaltigkeit in der Landtechnikherstellung und des Nachhaltigkeitsengagements der Landtechnikhersteller zu ermitteln, wurden im Rahmen einer empirischen Untersuchung 273 Fragebögen (39 % von 700 versandten Fragebögen ausgewertet. Bei den Teilnehmern der Befragung handelt es sich um Kunden der Landmaschinenfabrik Rauch GmbH und Leiter landwirtschaftlicher Ausbildungsbetriebe (z. T. Nicht- Kunden. Insgesamt wird das Engagement der Unternehmen hinsichtlich der Nachhaltigkeit von den Landwirten positiv bewertet. Insbesondere werden dabei Aspekte, die der sozialen Säule der Nachhaltigkeit zuzuordnen sind, mit Nachhaltigkeitsengagement in Verbindung gebracht, wie beispielsweise Maßnahmen zur Mitarbeiterausbildung. Darüber hinaus werden aus dem Bereich der ökonomischen Säule der Nachhaltigkeit die Zukunfts- und Innovationsorientierung besonders hervorgehoben. Bezüglich ihrer Einschätzung hinsichtlich nachhaltiger Landmaschinen stehen für die Landwirte insbesondere die Qualität der Maschine, die Nachrüstbarkeit und die Qualität der mit der Maschine getätigten Arbeiten im Vordergrund.

  2. Receptive vocabulary analysis in Down syndrome.

    Science.gov (United States)

    Loveall, Susan J; Channell, Marie Moore; Phillips, B Allyson; Abbeduto, Leonard; Conners, Frances A

    2016-08-01

    The present study is an in-depth examination of receptive vocabulary in individuals with Down syndrome (DS) in comparison to control groups of individuals of similar nonverbal ability with typical development (TD) and non-specific etiology intellectual disability (ID). Verb knowledge was of particular interest, as it is known to be a predictor of later syntactic development. Fifty participants with DS, aged 10-21 years, 29 participants with ID, 10-21 years, and 29 participants with TD, 4-9 years, completed measures of receptive vocabulary (PPVT-4), nonverbal ability (Leiter-R), and phonological memory (Nonword Repetition subtest of the CTOPP). Groups were compared on percentage correct of noun, verb and attribute items on the PPVT-4. Results revealed that on verb items, the participants with ID performed significantly better than both participants with DS and TD, even when overall receptive vocabulary ability and phonological memory were held constant. Groups with DS and TD showed the same pattern of lexical knowledge, performing better on nouns than both verbs and attributes. In contrast, the group with ID performed similarly on nouns and verbs, but worse on attributes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Generational differences in distress, attitudes and incivility among nurses.

    Science.gov (United States)

    Leiter, Michael P; Price, Sheri L; Spence Laschinger, Heather K

    2010-11-01

    The first research objective was to replicate the finding of Leiter et al. [(2008)Journal of Nursing Management, 16, 100-109.] of Generation X nurses (n=338) reporting higher levels of distress than Baby Boomer nurses (n=139). The second objective was to test whether Generation X nurses reported more negative social environments at work than did Baby Boomer nurses. Negative social environments can influence the quality of work and the experience of distress for nurses. Generational differences in the experience of distress and collegiality have implications for the establishment of healthy workplaces, recruitment and retention. A questionnaire survey of nurses was organized by generation. Analyses of variance contrasted the scores on burnout, turnover intention, physical symptoms, supervisor incivility, coworker incivility and team civility. The results confirmed the hypotheses of Generation X nurses reporting more negative experiences than did Baby Boomer nurses on all measures. The negative quality of social encounters at work contributes to nurses' experience of distress and suggest conflicts of values with the dominant culture of their workplaces. Proactive initiatives to enhance the quality of collegiality can contribute to retention strategies. Building collegiality across generations can be especially useful. © 2010 The Authors. Journal compilation © 2010 Blackwell Publishing Ltd.

  4. Bayley-III Scales of Infant and Toddler Development: Transcultural Adaptation and Psychometric Properties

    Directory of Open Access Journals (Sweden)

    Vanessa Madaschi

    2016-08-01

    Full Text Available Abstract Scales with evidence of validity and reliability are important to evaluate child development. In Brazil, there is a lack of standardized instruments to evaluate young children. This study investigated the psychometric properties of the Bayley Scales of Infant Development, Third Edition (Bayley-III. It was translated into Brazilian Portuguese, culturally adapted and tested on 207 children (12-42 months of age. Evidence of convergent validity was obtained from correlations of the Bayley-III with the: Peabody Developmental Motor Scale 2, Leiter International Performance Scale-R, Expressive Vocabulary Assessment List and Peabody Picture Vocabulary Test. Exploratory factor analyses showed a single component explaining 86% of the variance, supported by goodness-of-fit indexes in confirmatory factor analysis. The Bailey-III demonstrated good internal consistency with alpha coefficients greater than or equal to .90 and stability for fine motor scale only. These robust psychometric properties support the use of this tool in future national studies on child development.

  5. Interkulturelle Kompetenz in der Facharztausbildung von Psychiatern in Deutschland: Ergebnisse einer Umfrage [Intercultural competence in the psychiatric training curriculum in Germany: Results of a survey

    Directory of Open Access Journals (Sweden)

    Machleidt, Wielant

    2008-08-01

    Psychiatrie und Psychotherapie in Deutschland. Methodik: Es wurde ein semistrukturierter Fragebogen mit 30 Fragen (davon 28 strukturiert, 2 mit Freitextangaben entwickelt, der sich an den „Local Survey of Realities in Transcultural Psychiatry“ der (APA anlehnt und für Deutschland modifiziert wurde. Dieser wurde an die Leiter aller psychiatrischen Weiterbildungsinstitutionen in Deutschland verschickt (n=450. Als psychiatrische Weiterbildungsinstitutionen wurden diejenigen klinischen Einrichtungen definiert, deren Leiter über eine Ermächtigung zur Facharztweiterbildung durch die Landesärztekammern verfügen. Der Rücklauf erfolgte nicht anonymisiert. Ergebnisse: Die Rücklaufquote betrug 25,5% (Gesamt-N=114. In 71,7% der Weiterbildungsinstitutionen (n=81/113 gültige Fälle wurden in der klinikinternen Weiterbildung Themen aus dem Gebiet der transkulturellen Psychiatrie selten oder gar nicht angesprochen. 83,3% der Weiterbildungsleiter (n=70/84 gültige Fälle formulierten Bedarf an Weiterbildung in transkultureller Psychiatrie für die jeweils eigene Institution, 94,5% (n=69/73 gültige Fälle sahen den Bedarf grundsätzlich auch für das Curriculum der Facharztausbildung in Psychiatrie und Psychotherapie. Die am häufigsten genannten Themen betrafen eine allgemeine Schulung kultureller Kompetenz sowie kulturspezifische Aspekte seelischer Erkrankungen. Schlussfolgerungen: Im Rahmen der Weiterbildungsordnung zum Facharzt für Psychiatrie und Psychotherapie sind aktuell in keinem Bundesland entsprechende Inhalte aus dem Bereich der transkulturellen Psychiatrie verankert. Angesichts des formulierten Bedarfs muss die Implementierung eines entsprechenden Curriculums in die Weiterbildungsordnung zum Facharzt für Psychiatrie und Psychotherapie diskutiert werden.

  6. Quality Of Life And Prevalence Of Burnout Syndrome In Higher Education Teachers

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes Campos

    2017-09-01

    Full Text Available Introduction: Burnout Syndrome, in the twenty-first century, appears among the most common mental disorder among teachers resulting from the interaction between  individual aspects and the working environment, interpreted as a response to chronic job stress.  Objective: To evaluate the prevalence of burnout syndrome and quality of life of higher education teachers in the city of Cajazeiras, Paraíba, Brazil.  Method: This is a descriptive cross-sectional study performed with 174 teachers from institutions of higher education.  Results: The burnout syndrome was observed in only 3.4% of teachers. However, the recorded data require a closer look at the health of the teachers investigated, since a considerable part of them are in the score limit for disease development. Regarding the quality of life of teachers who presented the manifestations of the syndrome, the physical and psychological domains were shown to be the worst for most subjects.  Conclusion: There are teachers in higher education, executing their  profession, affected by burnout syndrome, suggesting a  relationship between this psychosocial phenomenon and the labor context, permeating  the three dimensions proposed by Maslach and Leiter: emotional exhaustion, depersonalization and the lack of personal fulfillment.   DOI: https://doi.org/10.3823/2512

  7. Ongoing clinical trials of the pleiotropic effects of statins

    Directory of Open Access Journals (Sweden)

    Jean Davignon

    2005-04-01

    Full Text Available Jean Davignon1, Lawrence A Leiter21Clinical Research Institute of Montreal, Montreal, QC, Canada; 2Division of Endocrinology and Metabolism, St Michael’s Hospital, Toronto, ON, CanadaBackground: The multiple effects (ie, pleiotropic effects of statins have received increasing recognition and may have clinical applicability across a broad range of cardiovascular and noncardiovascular conditions. Objective: To determine the relevance and significance of ongoing clinical trials of the pleiotropic effects of statins, focusing on nonlipid effects. Method: Ongoing trials were identified through personal communication, reports presented at scientific meetings (2000–2004, and queries made to AstraZeneca, Bristol-Myers Squibb Co, Merck & Co, Novartis, and Pfizer, manufacturers of the currently marketed statins. Published trials and other source material were identified through electronic searches on MEDLINE (1990–2003, abstract books, and references identified from bibliographies of pertinent articles. Eligible studies were the clinical trials of statins currently under way in which primary or secondary outcomes included the statins’ nonlipid (ie, pleiotropic effect(s. Data were extracted and trial quality was assessed by the authors. Results: Of the 22 ongoing trials of the nonlipid effects of statins identified, 10 assessed inflammatory markers and plaque stabilization, 4 assessed oxidized low density lipoprotein/vascular oxidant stress, 3 assessed end-stage renal disease, 3 assessed fibrinogen/viscosity, 2 assessed endothelial function, 2 assessed acute coronary syndrome, 2 assessed aortic stenosis progression, and 1 each assessed hypertension, osteoporosis, ischemic burden, Alzheimer’s disease, multiple sclerosis, and stroke (outcomes often overlapped. Conclusion: Given the excellent safety and tolerability of statins as a class, full exploration of their pleiotropic effects has the potential to provide additional benefits to many patients

  8. The validation of a workplace incivility scale within the South African banking industry

    Directory of Open Access Journals (Sweden)

    Olivia Smidt

    2016-05-01

    Full Text Available Orientation: Workplace incivility holds consequences for both individuals and organisations. Managers are becoming increasingly aware of this phenomenon. Currently, there is no workplace incivility scale validated for use within the South African context. Research purpose: To investigate the reliability and validity of the adapted workplace incivility scale by Leiter and colleagues for use within South Africa. Motivation for the study: As it is currently difficult to measure workplace incivility within the South African context because of the lack of a valid and reliable scale, it is necessary to validate such a scale. Research design, approach and method: A cross-sectional research approach was used for the study. Convenience sampling (N = 345 was used within the South African banking industry. Specifically, the factor structure, convergent validity, discriminant validity and predictive validity were investigated in order to establish the overall validity of the scale. Main findings: The results confirmed that the scale showed a three-factor structure as bestfitting with acceptable reliability coefficients. Furthermore, discriminant validity could be shown between workplace incivility and workplace bullying, that is, supporting that these two constructs are not the same phenomenon. In terms of relationships, colleague incivility did not significantly predict any of the outcome variables and instigated incivility only being a negative predictor of job satisfaction and a borderline statistically significant negative predictor of work engagement. However, supervisor incivility predicted all the outcomes negatively. Practical/Managerial implications: Based on the results, workplace incivility should be addressed because of the harmful effects it can have, not only on employees but also on organisations. It is therefore necessary for managers to create awareness of workplace incivility in order to ensure that it does not integrate within the

  9. Development and testing of high temperature-vector-SQUID conductor-magnetometers for the electro-magnetic exploration of our deposits. Final report; SQUID-Anwendungen - Entwicklung und Erprobung von Hochtemperatur-Vektor-Supraleiter SQUID-Magnetometern fuer die elektromagnetische Exploration von Lagerstaetten. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Matzander, U.; Friedrichs, B.

    2000-03-01

    Aim of the was the development of a prototype of a 3 axis HTc SQUID magnetometer for the geophysical exploration. The prototype was tested during the project in Germany and in China. Metronix task was the supervision of the development with the direction that the sensor can be used for field measurements and that the manufacturing costs will be acceptable. For magnetotelluric measurements (MT/CSAMT) further development is required to enhance the drift and noise properties of the sensor. The advantages in the geophysical TEM exploration are: greater sounding depth and good conductors (ore bodies) can be penetrated completely; the thickness of the resource can be estimated this way. At the same time the measuring time can be reduced tremendously because of the better signal to noise ratio. The productivity of the measuring campaign increases. If due to further developments coils systems can be replaced in total by the SQUID, SQUID systems will dominate the TEM market. (orig.) [German] Ziel des Projektes war es, einen Prototyp eines 3-achsigen HTc SQUIDS zur Verfuegung zu haben, welcher die Anforderungen fuer geophysikalische Messungen erfuellt. Dieser Prototyp wurde im Laufe des Projektes in Deutschland und China getestet. Die Rolle der Firma Metronix in diesem Projekt war die Einflussnahme auf die Entwicklung in der Form, dass zum einen die aus der Feldmesstechnik resultierenden Anforderungen beruecksichtigt werden, zum anderen auf eine spaetere kostenguenstige Herstellung geachtet wird. Bei magnetotellurischen Messungen (MT/CSAMT) besteht weiterer Bedarf an Verbesserungen hinsichtlich der Drift- und Rauscheigenschaften des Sensors. Fuer die geophysikalische Exploration in der TEM ergeben sich folgende Vorteile: die Erkundungstiefe ist groesser und gute Leiter (Erzkoerper) koennen vollstaendig durchteuft werden; damit kann die Maechtigkeit des Vorkommens bestimmt werden. Gleichzeitig kann auf Grund des besseren Signal / Rauschverhaeltnisses die Messzeit deutlich

  10. The validation of a workplace incivility scale within the South African banking industry

    Directory of Open Access Journals (Sweden)

    Olivia Smidt

    2016-04-01

    Full Text Available Orientation: Workplace incivility holds consequences for both individuals and organisations. Managers are becoming increasingly aware of this phenomenon. Currently, there is no workplace incivility scale validated for use within the South African context. Research purpose: To investigate the reliability and validity of the adapted workplace incivility scale by Leiter and colleagues for use within South Africa. Motivation for the study: As it is currently difficult to measure workplace incivility within the South African context because of the lack of a valid and reliable scale, it is necessary to validate such a scale.Research design, approach and method: A cross-sectional research approach was used for the study. Convenience sampling (N = 345 was used within the South African banking industry. Specifically, the factor structure, convergent validity, discriminant validity and predictive validity were investigated in order to establish the overall validity of the scale. Main findings: The results confirmed that the scale showed a three-factor structure as bestfitting with acceptable reliability coefficients. Furthermore, discriminant validity could be shown between workplace incivility and workplace bullying, that is, supporting that these two constructs are not the same phenomenon. In terms of relationships, colleague incivility did not significantly predict any of the outcome variables and instigated incivility only being a negative predictor of job satisfaction and a borderline statistically significant negative predictor of work engagement. However, supervisor incivility predicted all the outcomes negatively. Practical/Managerial implications: Based on the results, workplace incivility should be addressed because of the harmful effects it can have, not only on employees but also on organisations. It is therefore necessary for managers to create awareness of workplace incivility in order to ensure that it does not integrate within the

  11. Unusual resistance of ALR/Lt mouse β cells to autoimmune destruction: Role for β cell-expressed resistance determinants

    Science.gov (United States)

    Mathews, Clayton E.; Graser, Robert T.; Savinov, Alexei; Serreze, David V.; Leiter, Edward H.

    2001-01-01

    Genetic analysis of autoimmune insulin-dependent diabetes mellitus (IDDM) has focused on genes controlling immune functions, with little investigation of innate susceptibility determinants expressed at the level of target β cells. The Alloxan (AL) Resistant (R) Leiter (Lt) mouse strain, closely related to the IDDM-prone nonobese diabetic (NOD)/Lt strain, demonstrates the importance of such determinants. ALR mice are unusual in their high constitutive expression of molecules associated with dissipation of free-radical stress systemically and at the β-cell level. ALR islets were found to be remarkably resistant to two different combinations of β-cytotoxic cytokines (IL-1β, tumor necrosis factor α, and IFN-γ) that destroyed islets from the related NOD and alloxan-susceptible strains. The close MHC relatedness between the NOD and ALR strains (H2-Kd and H2-Ag7 identical) allowed us to examine whether ALR islet cells could survive autoimmune destruction by NOD-derived Kd-restricted diabetogenic cytotoxic T lymphocyte clones (AI4 and the insulin-reactive G9C8 clones). Both clones killed islet cells from all Kd-expressing strains except ALR. ALR resistance to diabetogenic immune systems was determined in vivo by means of adoptive transfer of the G9C8 clone or by chimerizing lethally irradiated ALR or reciprocal (ALR × NOD)F1 recipients with NOD bone marrow. In all in vivo systems, ALR and F1 female recipients of NOD marrow remained IDDM free; in contrast, all of the NOD recipients became diabetic. In conclusion, the ALR mouse presents a unique opportunity to identify dominant IDDM resistance determinants expressed at the β cell level. PMID:11136257

  12. The contribution of short-term memory capacity to reading ability in adolescents with cochlear implants.

    Science.gov (United States)

    Edwards, Lindsey; Aitkenhead, Lynne; Langdon, Dawn

    2016-11-01

    This study aimed to establish the relationship between short-term memory capacity and reading skills in adolescents with cochlear implants. A between-groups design compared a group of young people with cochlear implants with a group of hearing peers on measures of reading, and auditory and visual short-term memory capacity. The groups were matched for non-verbal IQ and age. The adolescents with cochlear implants were recruited from the Cochlear Implant Programme at a specialist children's hospital. The hearing participants were recruited from the same schools as those attended by the implanted adolescents. Participants were 18 cochlear implant users and 14 hearing controls, aged between 12 and 18 years. All used English as their main language and had no significant learning disability or neuro-developmental disorder. Short-term memory capacity was assessed in the auditory modality using Forward and Reverse Digit Span from the WISC IV UK, and visually using Forward and Reverse Memory from the Leiter-R. Individual word reading, reading comprehension and pseudoword decoding were assessed using the WIAT II UK. A series of ANOVAs revealed that the adolescents with cochlear implants had significantly poorer auditory short-term memory capacity and reading skills (on all measures) compared with their hearing peers. However, when Forward Digit Span was entered into the analyses as a covariate, none of the differences remained statistically significant. Deficits in immediate auditory memory persist into adolescence in deaf children with cochlear implants. Short-term auditory memory capacity is an important neurocognitive process in the development of reading skills after cochlear implantation in childhood that remains evident in later adolescence. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  13. Functional communication of children who are deaf or hard-of-hearing.

    Science.gov (United States)

    Meinzen-Derr, Jareen; Wiley, Susan; Grether, Sandra; Phillips, Jannel; Choo, Daniel; Hibner, Julie; Barnard, Holly

    2014-04-01

    The primary aim of this study was to investigate the relationship between language levels and communication and social function skills in young children who are deaf/hard-of-hearing. A cross-sectional design was used with participants sampled predominately from a single clinic setting. Children between 3 and 6 years of age with permanent bilateral hearing loss were enrolled in the study. All children received the Preschool Language Scales-Fifth Edition language assessment and a neurocognitive assessment using the Leiter International Performance Scale-Revised at the study visit. Communication and social function skills were measured using the Vineland Adaptive Behavior Scales-Second Edition (VABS-II; mean 100 ± 15) and the Pediatric Evaluation of Disability Inventory (PEDI; mean 50 ± 10). Analysis included 65 children with mild to profound bilateral hearing loss (mean age 56.8 months, SD ± 14.1); 52% had hearing loss in the mild to moderate range. The mean nonverbal intelligence quotient (IQ) was 95.7 (±18.8), the mean receptive language standard score was 83.7 (±18.6), and mean expressive language standard score was 83.0 (±18.5). The mean VABS-II communication standard score was 89.1 (±17.5), and the mean PEDI social function score was 39.6 (±15.3). Both nonverbal IQ and receptive language relative to nonverbal IQ (the ratio of language to IQ) were significantly associated with communication and social functioning, explaining more than 50% of the variance in communication function scores. Children with language commensurate with their IQ had significantly higher communication and social function scores than children with language significantly lower than IQ. This finding was consistent across different levels of IQ and independent of degree of hearing loss. Even with early identification and intervention, hearing loss continues to have a life-long impact on functioning. It is important to identify when language levels are not meeting a child's capabilities

  14. Strategien für Medizinbibliotheken [Strategies for medical libraries

    Directory of Open Access Journals (Sweden)

    Bauer, Bruno

    2013-11-01

    Full Text Available [english] The focus of the current issue 1-2/2013 of GMS Medizin – Bibliothek – Information is on strategies for medical libraries. Head librarians of medical libraries from Berlin, Bochum, Graz, Mainz, Mannheim, Münster and Vienna present their individual approaches for a successful future. The authors in this issue are Ulf Paepcke (Development of the journal holdings at the Medical Library of the Charité 2005–2013, Annette Kustos (The new Academic Health Sciences, Nursing and Therapeutics Library of the Hochschule für Gesundheit (hsg Bochum - interim report of a strategically oriented planning, Ulrike Kortschak (Library mainstream versus the challenge of developing a profile?, Stefanus Seizer (Strategic development of medical libraries from the perspective of a department library, Martina Semmler-Schmetz & Maria-Inti Metzendorf (Opening up new tasks through cooperation and networking – service development in the Library for the Medical Faculty of Mannheim, Oliver Obst ((No strategy for medical libraries? and Bruno Bauer (Medical libraries boost innovations for the digital library: The university library of the Medical University Vienna as an example for the metamorphosis of scientific libraries.[german] Das Schwerpunktthema der aktuellen Ausgabe 1-2/2013von GMS Medizin – Bibliothek – Information lautet Strategien für Medizinbibliotheken. Bibliotheksleiterinnen und -leiter aus Berlin, Bochum, Graz, Mainz, Mannheim, Münster und Wien stellen ihre individuellen Überlegungen für eine erfolgreiche Zukunft vor. Verfasst wurden die Beiträge der Schwerpunktausgabe von Ulf Paepcke (Die Entwicklung des Zeitschriftenbestands an der Medizinischen Bibliothek der Charité in den Jahren 2005–2013, Annette Kustos (Die neue Hochschulbibliothek für Gesundheitswissenschaften der Hochschule für Gesundheit (hsg Bochum – Zwischenbericht einer strategisch angelegten Planung, Ulrike Kortschak (Bibliothekarischer Mainstream oder Profilbildung

  15. Intelligent quotient estimation of mental retarded people from different psychometric instruments using artificial neural networks.

    Science.gov (United States)

    Di Nuovo, Alessandro G; Di Nuovo, Santo; Buono, Serafino

    2012-02-01

    The estimation of a person's intelligence quotient (IQ) by means of psychometric tests is indispensable in the application of psychological assessment to several fields. When complex tests as the Wechsler scales, which are the most commonly used and universally recognized parameter for the diagnosis of degrees of retardation, are not applicable, it is necessary to use other psycho-diagnostic tools more suited for the subject's specific condition. But to ensure a homogeneous diagnosis it is necessary to reach a common metric, thus, the aim of our work is to build models able to estimate accurately and reliably the Wechsler IQ, starting from different psycho-diagnostic tools. Four different psychometric tests (Leiter international performance scale; coloured progressive matrices test; the mental development scale; psycho educational profile), along with the Wechsler scale, were administered to a group of 40 mentally retarded subjects, with various pathologies, and control persons. The obtained database is used to evaluate Wechsler IQ estimation models starting from the scores obtained in the other tests. Five modelling methods, two statistical and three from machine learning, that belong to the family of artificial neural networks (ANNs) are employed to build the estimator. Several error metrics for estimated IQ and for retardation level classification are defined to compare the performance of the various models with univariate and multivariate analyses. Eight empirical studies show that, after ten-fold cross-validation, best average estimation error is of 3.37 IQ points and mental retardation level classification error of 7.5%. Furthermore our experiments prove the superior performance of ANN methods over statistical regression ones, because in all cases considered ANN models show the lowest estimation error (from 0.12 to 0.9 IQ points) and the lowest classification error (from 2.5% to 10%). Since the estimation performance is better than the confidence interval of

  16. 教室環境における言語発達の分析に向けた記述の枠組み

    OpenAIRE

    伊藤, 崇; 茂呂, 雄二

    2002-01-01

    This paper proposes a framework for analyzing language development. Inthis proposal, language development is understood as change within physical and social relationships. This view emphasizes institutional transitions ...

  17. ENU Mutagenic Screen for Susceptibility and Resistance to Streptococcus Pneumoniae

    National Research Council Canada - National Science Library

    Kindy, Mark S

    2005-01-01

    .... The genetic pathways that control susceptibility and resistance to bacterial infection have remained poorly understood, because of the lack of expertise in the development of techniques capable...

  18. Single Crystal Silicon Mirrors for Spaceflight Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop a well understood process for manufacturing visible quality SCSi mirrors. Areas of research include stress relief, figure, finish, and light weighting...

  19. 76 FR 69801 - Conductor Certification

    Science.gov (United States)

    2011-11-09

    ... clearly understood. A. Definitions 1. Substance Abuse Professional (SAP) FRA solicited comments whether a... have traditionally been known as certified engineers, conductors, brakemen, yard helpers, and yardmen...

  20. The Role of Costimulatory Molecules in the Development of Memory and Effector T Helper 2 Cells During an in vivo Immune Response to the Murine Gastrointestinal Parasite Heligmosomoides polygyrus

    National Research Council Canada - National Science Library

    Ekkens, Melinda

    2002-01-01

    ...+ T cell differentiation is not well understood. One model used to study the Th immune response involves oral infection of mice with the gastrointestinal nematode parasite Heligmosomoides polygyrus...

  1. Energy Literacy : Essential Principles and Fundamental Concepts for Energy Education

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-08-01

    Energy Literacy: Essential Principles and Fundamental Concepts for Energy Education presents energy concepts that, if understood and applied, will help individuals and communities make informed energy decisions.

  2. Energy Literacy : Essential Principles and Fundamental Concepts for Energy Education

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-03-01

    Energy Literacy: Essential Principles and Fundamental Concepts for Energy Education presents energy concepts that, if understood and applied, will help individuals and communities make informed energy decisions.

  3. 78 FR 37468 - Cyproconazole; Pesticide Tolerances

    Science.gov (United States)

    2013-06-21

    ... regenerative proliferation as alternative modes of action. The quantification of carcinogenic potential is not..., stress responses, and altered DNA methylation. It is not clearly understood whether these biochemical...

  4. Nationwide fluoroscopic screening of recalled riata defibrillator leads in denmark

    DEFF Research Database (Denmark)

    Larsen, Jacob M; Riahi, Sam; Nielsen, Jens Carl Ry

    2013-01-01

    The natural history of insulation defects with inside-out conductor externalization in recalled St Jude Medical Riata defibrillator leads is not well understood.......The natural history of insulation defects with inside-out conductor externalization in recalled St Jude Medical Riata defibrillator leads is not well understood....

  5. Adaptive speciation theory : A conceptual review

    NARCIS (Netherlands)

    Weissing, Franz J.; Edelaar, Pim; van Doorn, G. Sander

    Speciation-the origin of new species-is the source of the diversity of life. A theory of speciation is essential to link poorly understood macro-evolutionary processes, such as the origin of biodiversity and adaptive radiation, to well understood micro-evolutionary processes, such as allele

  6. Moral Functioning: Navigating the Messy Landscape of Values in Finnish Preschools

    Science.gov (United States)

    Puroila, Anna-Maija; Haho, Annu

    2017-01-01

    This article employs a narrative approach to explore educators' moral functioning in Finnish preschools. Our study is theoretically inspired by notions drawn from feminist and sociocultural studies, according to which education is understood as an entirely moral phenomenon. Within a holistic framework, moral functioning is understood as a concept…

  7. Sleep research goes wild : New methods and approaches to investigate the ecology, evolution and functions of sleep

    NARCIS (Netherlands)

    Rattenborg, Niels C; de la Iglesia, Horacio O; Kempenaers, Bart; Lesku, John A; Meerlo, Peter; Scriba, Madeleine F

    2017-01-01

    Despite being a prominent aspect of animal life, sleep and its functions remain poorly understood. As with any biological process, the functions of sleep can only be fully understood when examined in the ecological context in which they evolved. Owing to technological constraints, until recently,

  8. Wishful Thinking and the Unconscious: A Reply to Gouws | Galgut ...

    African Journals Online (AJOL)

    This paper argues against the view that the Freudian unconscious can be understood as an extension of ordinary belief-desire psychology. The paper argues that Freud\\'s picture of the mind challenges the paradigm of folk psychology, as it is understood by much contemporary philosophy of psychology and cognitive ...

  9. Emotions Targeting Moral Exemplarity: Making Sense of the Logical Geography of Admiration, Emulation and Elevation

    Science.gov (United States)

    Kristjánsson, Kristján

    2017-01-01

    Despite renewed interest in moral role-modelling and its emotional underpinnings, further conceptual work is needed on the logical geography of the emotions purportedly driving it, in particular, admiration, emulation and elevation. In this article, I explore admiration (as understood by Linda Zagzebski), emulation (as understood by Aristotle) and…

  10.   Transformation of the industrial harbor areas to housing areas

    DEFF Research Database (Denmark)

    Rehder, Meike

    2009-01-01

    Research question: How to read the universal (understood as the common and the social) and the individual (understood as the specific, private and intimate) in the meeting between urban and housing space? Questions in the project: How do the exterior spaces in these new harbour areas come to being...

  11. Book reviews

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    2009-01-01

    The review consists of two sections: In the first, community education is understood as an invitation to develop transversal, transdisciplinary research on a European level and dealing with adult education in order to improve a social Europe. In the second, the European question is understood as ...

  12. Hexokinase 2, glycogen synthase and phosphorylase play a key role in muscle glycogen supercompensation

    DEFF Research Database (Denmark)

    Irimia, José M; Rovira, Jordi; Nielsen, Jakob N

    2012-01-01

    Glycogen-depleting exercise can lead to supercompensation of muscle glycogen stores, but the biochemical mechanisms of this phenomenon are still not completely understood.......Glycogen-depleting exercise can lead to supercompensation of muscle glycogen stores, but the biochemical mechanisms of this phenomenon are still not completely understood....

  13. Anger, hatred, or just heartlessness?: Defining gratuitous violence ...

    African Journals Online (AJOL)

    Violent crime in South Africa is sometimes said to be unusual, because it is perceived to frequently be gratuitous. This article engages with the question of how to define gratuitous violence. If the term gratuitous is understood to mean 'for nothing', gratuitous violence should be understood as violence that is 'low on ...

  14. Constellations of New Demands Concerning Careers and Jobs: Results from a Two-Country Study on Social and Economic Change

    Science.gov (United States)

    Obschonka, Martin; Silbereisen, Rainer K.; Wasilewski, Jacek

    2012-01-01

    Focusing on new demands posed by social and economic change, and applying a pattern-based approach, this study examined constellations of increasing labor market uncertainties (understood as threat) and increasing job-related learning tasks (understood as positive challenge). We investigated whether and how the groups of working individuals behind…

  15. Investigating Friendship Quality: An Exploration of Self-Control and Social Control Theories' Friendship Hypotheses

    Science.gov (United States)

    Boman, John H., IV; Krohn, Marvin D.; Gibson, Chris L.; Stogner, John M.

    2012-01-01

    While associations with deviant peers are well understood to impact individual development, less is understood about the relationship between friendship quality and delinquency. Two criminological theories--social control theory and self-control theory--are able to offer an explanation for the latter relationship. Social control and self-control…

  16. Information as signs: A semiotic analysis of the information concept, determining it's ontological and epistemological commitments

    DEFF Research Database (Denmark)

    Thellefsen, Martin Muderspach; Thellefsen, Torkild Leo; Sørensen, Bent

    2018-01-01

    , or conversely, information is understood only relative to subjective/discursive intentions, agendas, etc. To overcome the limitations of defining information as either objective or subjective/discursive, a semiotic analysis shows that information understood as signs is consistently sensitive to both objective...

  17. Predictors of objective cough frequency in chronic obstructive pulmonary disease

    DEFF Research Database (Denmark)

    Sumner, Helen; Woodcock, Ashley; Kolsum, Umme

    2013-01-01

    Cough is one of the principal symptoms of chronic obstructive pulmonary disease (COPD) but the potential drivers of cough are likely to be multifactorial and poorly understood.......Cough is one of the principal symptoms of chronic obstructive pulmonary disease (COPD) but the potential drivers of cough are likely to be multifactorial and poorly understood....

  18. Disability Discourse: Overview and Critiques of the Medical and Social Models

    Science.gov (United States)

    Haegele, Justin Anthony; Hodge, Samuel

    2016-01-01

    Over time, the meaning of disability has been understood in a variety of ways. The way in which disability is understood is important because the language people use to describe individuals with disabilities influences their expectations and interactions with them. For physical education teachers, philosophical orientation in regard to disability…

  19. 40 CFR 211.103 - Number and gender.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Number and gender. 211.103 Section 211... PRODUCT NOISE LABELING General Provisions § 211.103 Number and gender. In this part, words in the singular will be understood to include the plural, and words in the masculine gender will be understood to...

  20. Understanding the peri-urban economy

    DEFF Research Database (Denmark)

    Monsson, Christian Kjær

    2013-01-01

    Christian Kjær Monsson suggests that the peri-urban economy should be understood as a metaphor of a mosaic.......Christian Kjær Monsson suggests that the peri-urban economy should be understood as a metaphor of a mosaic....

  1. Buy Low, Sell High: The Development of an Informal Theory of Economics.

    Science.gov (United States)

    Thompson, Douglas R.; Siegler, Robert S.

    2000-01-01

    Two experiments examined development of economic understanding among 5-, 7- and 9-year-olds. Found that most 5-year-olds understood the goal of acquiring desired goods, and most 7- and 9-year-olds also understood the goals of seeking profits, acquiring goods inexpensively, and competing successfully with other sellers. Results suggest that older…

  2. Interaction of solitary pulses in single mode optical fibres | Usman ...

    African Journals Online (AJOL)

    Two solitary waves launched, by way of incidence, into an optical fibre from a single pulse if the pulses are in-phase as understood from results of inverse scattering transform method applied to the cubic nonlinear Schrödinger equations, (CNLSE\\'s). The single CNLSE is then understood to describe evolution of coupled ...

  3. Cognitive ability in early adulthood as a predictor of habitual drug use during later military service and civilian life

    DEFF Research Database (Denmark)

    White, James; Mortensen, Laust Hvas; Batty, G David

    2012-01-01

    Recent reports have linked cognitive ability (IQ) with alcohol dependency, but the relationship with illegal drug use is not well understood.......Recent reports have linked cognitive ability (IQ) with alcohol dependency, but the relationship with illegal drug use is not well understood....

  4. Self-Reported Drug and Alcohol Use and Attitudes toward Drug Testing in High Schools with Random Student Drug Testing

    Science.gov (United States)

    DuPont, Robert L.; Campbell, Michael D.; Campbell, Teresa G.; Shea, Corinne L.; DuPont, Helen S.

    2013-01-01

    Many schools implement random student drug testing (RSDT) programs as a drug prevention strategy. This study analyzes self-report surveys of students in eight secondary schools with well-established RSDT programs, comparing students who understood they were subject to testing and students who understood they were not subject to testing. Students…

  5. Academic Airframe Icing Perspective

    Science.gov (United States)

    Bragg, Mike; Rothmayer, Alric; Thompson, David

    2009-01-01

    2-D ice accretion and aerodynamics reasonably well understood for engineering applications To significantly improve our current capabilities we need to understand 3-D: a) Important ice accretion physics and modeling not well understood in 3-D; and b) Aerodynamics unsteady and 3-D especially near stall. Larger systems issues important and require multidisciplinary team approach

  6. Facilitating Problem Framing in Project-Based Learning

    Science.gov (United States)

    Svihla, Vanessa; Reeve, Richard

    2016-01-01

    While problem solving is a relatively well understood process, problem framing is less well understood, particularly with regard to supporting students to learn as they frame problems. Project-based learning classrooms are an ideal setting to investigate how teachers facilitate this process. Using participant observation, this study investigated…

  7. Active learners in sustainable electronics and it

    DEFF Research Database (Denmark)

    Schultz, Ole

    This poster-presentation is about active learning in a course sustainable wireless electronics and it. Active learning understood as practical lab-exercises and a team chosen project.......This poster-presentation is about active learning in a course sustainable wireless electronics and it. Active learning understood as practical lab-exercises and a team chosen project....

  8. Upper and lower airway patency are associated in young children

    DEFF Research Database (Denmark)

    Chawes, Bo Lund Krogsgaard; Kreiner-Møller, Eskil; Bisgaard, Hans

    2010-01-01

    Although allergic rhinitis and asthma frequently coexist, the nature of this association is poorly understood. Therefore, we examined whether upper and lower airway patency are associated.......Although allergic rhinitis and asthma frequently coexist, the nature of this association is poorly understood. Therefore, we examined whether upper and lower airway patency are associated....

  9. A hidden bias in a common calorimeter calibration scheme

    International Nuclear Information System (INIS)

    Lincoln, Don; Morrow, Greg; Kasper, Peter

    1994-01-01

    In this paper, a common calorimeter calibration scheme is explored and a hidden bias found. Since this bias mimics a non-linearity in response in the calorimeter, it must be understood and removed from the calibration before true non-linearities are investigated. The effect and its removal are explored and understood through straightforward calculus and algebra. ((orig.))

  10. Origins of executive pay & corporate governance reform codes : Essays on an institutional approach to corporate governance

    NARCIS (Netherlands)

    Otten, J.A.

    2007-01-01

    Typically corporate governance is analyzed and understood on the basis of agency theory. This theory is not only the dominant one in academic research, it is also understood as the dominant lens by which policy makers and practitioners ought to see the field. Nevertheless, in order to provide more

  11. Characterisation of and reflections on the synergy of bicycles and public transport

    NARCIS (Netherlands)

    Kager, R.; Bertolini, L.; te Brömmelstroet, M.

    2016-01-01

    The bicycle is often understood as a disjointed ‘feeder’ mode that provides access to public transport. We argue that combined use of the bicycle and public transport should be understood in a broader perspective, especially where bicycles link to higher speed and higher capacity public transport,

  12. Walter Benjamin's Conception of Experience: A Way of Thinking about Otherness in Educational Context

    Science.gov (United States)

    Tsuji, Atsuko

    2014-01-01

    In the context of educational practice and research, the individual is often understood in terms of autonomy. From this point of view, we will see our experience as cumulative, as inside of us, and as strengthening us against others. It means that the conception of experience tends to be understood primarily in relation to usefulness. In search of…

  13. Corticosteroids reduce the tensile strength of isolated collagen fascicles

    DEFF Research Database (Denmark)

    Haraldsson, Bjarki Thor; Langberg, Henning; Aagaard, Per

    2006-01-01

    Overuse tendon injuries are frequent. Corticosteroid injections are commonly used as treatment, although their direct effects on the material properties of the tendon are poorly understood.......Overuse tendon injuries are frequent. Corticosteroid injections are commonly used as treatment, although their direct effects on the material properties of the tendon are poorly understood....

  14. Lower extremity performance following ACL rehabilitation in the KANON-trial

    DEFF Research Database (Denmark)

    Ericsson, Ylva B; Roos, Ewa M.; Frobell, Richard B

    2013-01-01

    The additional effect of anterior cruciate ligament (ACL) reconstruction on muscle strength and physical performance after a structured exercise programme is not well understood.......The additional effect of anterior cruciate ligament (ACL) reconstruction on muscle strength and physical performance after a structured exercise programme is not well understood....

  15. Communication as Relational Practice of Leading

    DEFF Research Database (Denmark)

    Hansen, Lone Hersted; Larsen, Mette Vinther; Rasmussen, Jørgen Gulddahl

    2015-01-01

    This chapter highlights how communication, especially leadership communication, can be understood and practised within a relational perspective. An analysis of a specific example of communication forms the basis for a discussion of six central themes that we consider significant in a relational...... understanding of communication and leading. The chapter ends with a discussion of how leadership communication can be understood as polyphony of voices....

  16. Explaining Biological Functionality: Is Control Theory Enough ...

    African Journals Online (AJOL)

    I argue that the etiological approach, as understood in terms of control theory, suffers from a problem of symmetry, by which function can equally well be placed in the environment as in the organism. Focusing on the autonomy view, I note that it can be understood to some degree in terms of control theory in its version called ...

  17. Intellectuals For Hire.

    Science.gov (United States)

    Morrill, Cynthia

    1999-01-01

    Suggests that working beyond the academy should be understood not as an abandonment of the academic job market, a response to failure, or a curse: instead, it should be understood as a new avenue for intellectual work, one that neither graduate-school programs nor the Modern Language Association would be wise to ignore. (RS)

  18. Counter narratives inplace and city branding and their influence on brand mangement

    DEFF Research Database (Denmark)

    Jørgensen, Ole Have

    2016-01-01

    The study is aimed at describing the types of counter narratives evolving in a city brand process, how they are understood and dealt with and how they may influence brand mangement.......The study is aimed at describing the types of counter narratives evolving in a city brand process, how they are understood and dealt with and how they may influence brand mangement....

  19. The heterogeneity of surfaces of magnetic Ap stars

    International Nuclear Information System (INIS)

    Hack, M.

    1977-01-01

    The observations of spectrum-variability and light-variability of Ap stars are reviewed. It is shown that these variations are interpretable as due to the changing aspect of the spotted surface as the star rotates. It is stressed that the geometry of the phenomenon is understood fairly well but the physics is very far from being understood. (Auth.)

  20. Current perspectives in vulvodynia

    DEFF Research Database (Denmark)

    Damsted-Petersen, Christina; Boyer, Stéphanie C; Pukall, Caroline F

    2009-01-01

    Vulvodynia, or chronic vulvar pain, is a common but poorly understood condition. Although its etiology is not well understood, it appears to be multifactorial. As such, treatment options are targeted to reduce singular symptoms in a piecemeal fashion. A number of randomized, controlled trials have...

  1. Luther and the Law in the Lutheran Church of Uganda | Ekyarikunda ...

    African Journals Online (AJOL)

    This article investigates the role of the Law in the Lutheran Church of Uganda. It investigates how the Law is understood and lived among Lutherans in Uganda. Luther, the sixteenthcentury Reformer, understood and interpreted the Law in terms of the social and cultural context of his time. Luther's background is very ...

  2. the effect of hypertension on neurocognitive functioning and quality ...

    African Journals Online (AJOL)

    Esem

    hypertension is seen as subtle deficits in many domains of. 4 neuropsychological performance . The effect of hypertension on neurocognitive functioning remains. 4 poorly understood .The mechanisms that lead to cognitive decline in hypertensives are not fully understood yet, however knowledge in this area of study is. 9.

  3. Psychodiagnostic Properties of the Piotr Oles´ "Internal Dialogical Activity Scale"

    Science.gov (United States)

    Astretsov, D. A.; Leontiev, D. A.

    2016-01-01

    The article discusses the concept of internal dialogue and how it is understood in various schools of psychological research, including both Russia and abroad. The authors briefly investigate how the concept was understood by Mikhail Bakhtin, Lev Vygotsky, G.M. Kuchinskii, and Hubert Hermans. The "Internal Dialogical Activity Scale"…

  4. A call for the restoration of orthodoxy in South African Christian ...

    African Journals Online (AJOL)

    Liberation theology can only be understood as a pseudo-theology inspired by the spirit of Marx. It is not a bona fide or leg itimate theology, but the polar opposite thereof. Its destructive aims mirror those of Marxism, which can only be understood if the demonic spirit of Marx is seen as its real origin. The Kairos Document and ...

  5. Ants farm subterranean aphids mostly in single clone groups : An example of prudent husbandry for carbohydrates and proteins?

    NARCIS (Netherlands)

    Ivens, Aniek B. F.; Kronauer, Daniel J. C.; Pen, Ido; Weissing, Franz J.; Boomsma, Jacobus J.

    2012-01-01

    Background: Mutualistic interactions are wide-spread but the mechanisms underlying their evolutionary stability and ecological dynamics remain poorly understood. Cultivation mutualisms in which hosts consume symbionts occur in phylogenetically diverse groups, but often have symbiont monocultures for

  6. Renal Handling of Circulating and Renal-Synthesized Hepcidin and Its Protective Effects against Hemoglobin-Mediated Kidney Injury.

    NARCIS (Netherlands)

    Swelm, R.P. van; Wetzels, J.F.; Verweij, V.G.; Laarakkers, C.M.; Pertijs, J.C.; Wijst, J.A. van der; Thevenod, F.; Masereeuw, R.; Swinkels, D.W.

    2016-01-01

    Urinary hepcidin may have protective effects against AKI. However, renal handling and the potential protective mechanisms of hepcidin are not fully understood. By measuring hepcidin levels in plasma and urine using mass spectrometry and the kidney using immunohistochemistry after intraperitoneal

  7. Morphological evolution and genetic differentiation in Daphnia species complexes

    NARCIS (Netherlands)

    Gießer, S.; Mader, E.; Schwenk, K.

    1999-01-01

    Despite many ecological and evolutionary studies, the history of several species complexes within the freshwater crustacean genus Daphnia (Branchiopoda, Anomopoda) is poorly understood. In particular, the Daphnia longispina group, comprising several large-lake species, is characterized by pronounced

  8. Effects of Nicotine Dependence and Depressive Symptoms on Smoking Cessation: A Longitudinal Study Among Adolescents

    NARCIS (Netherlands)

    Scherphof, C.S.; Eijnden, R.J.J.M. van den; Harakeh, Z.; Raaijmakers, Q.A.W.; Kleinjan, M.; Engels, R.C.M.E.; Vollebergh, W.A.M.

    2013-01-01

    Nicotine dependence has been shown to hamper successful smoking cessation in adolescents. Nicotine dependence and depression are highly comorbid, but the relation between depression and smoking cessation is not yet fully understood. Therefore, the present study examines both the longitudinal

  9. Thermodynamic principles governing metabolic operation : inference, analysis, and prediction

    NARCIS (Netherlands)

    Niebel, Bastian

    2015-01-01

    The principles governing metabolic flux are poorly understood. Because diverse organisms show similar metabolic flux patterns, we hypothesized that fundamental thermodynamic constraints might shape cellular metabolism. We developed a constraint-based model for Saccharomyces cerevisiae that included

  10. National Built Environment Health Impact Assessment Model: Creation and Application

    Science.gov (United States)

    Behavioral (activity, diet, social interaction) and exposure (air pollution, traffic injury, and noise) related health impacts of land use and transportation investment decisions are becoming better understood and quantified. Research has shown relationships between density, mix,...

  11. News with an attitude: assessing the mechanisms underlying the effects of opinionated news

    NARCIS (Netherlands)

    Boukes, M.; Boomgaarden, H.G.; Moorman, M.; de Vreese, C.H.

    2014-01-01

    Opinionated news targets communities of likeminded viewers, relies on dramaturgical storytelling techniques, and shares characteristics with political satire. Accordingly, opinionated news should be understood as a specific form of political entertainment. We have investigated the mechanisms

  12. Placebo Effect

    Science.gov (United States)

    ... the placebo. Some people wonder whether it is fair or ethical to give a placebo treatment to ... carefully done using a placebo, so that the true effect of the treatment can be fully understood. ...

  13. Short Communication Observations of individual humpback whales ...

    African Journals Online (AJOL)

    Movements of humpback whales Megaptera novaeangliae among breeding regions within the southwestern Indian Ocean are poorly understood. Understanding the relationships among breeding regions is critical for effective conservation and management strategies. Through systematic comparisons of molecular ...

  14. Peripartum Cardiomyopathy

    African Journals Online (AJOL)

    pregnant women. The pathophysiology is poorly understood. Echocardiography is central to diagnosis of PPCM and effective treatment monitoring in patients of PPCM. The outcome ... Keywords: Cardiomyopathy, Echocardiography, Peripartum, Pregnancy ... complicated by pre‑eclampsia, gestational hypertension,.

  15. Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: a randomized, double-blind, placebo-controlled trial

    NARCIS (Netherlands)

    Vranken, J. H.; Hollmann, M. W.; van der Vegt, M. H.; Kruis, M. R.; Heesen, M.; Vos, K.; Pijl, A. J.; Dijkgraaf, M. G. W.

    2011-01-01

    The mechanisms underlying central neuropathic pain are poorly understood. Pain inhibitory mechanisms including sertononergic and norepinephrine systems may be dysfunctional. In this randomized, double-blinded, placebo-controlled trial we evaluated the effects of duloxetine on pain relief

  16. Surface properties correlate to the digestibility of hydrothermally pretreated lignocellulosic Poaceae biomass feedstocks

    DEFF Research Database (Denmark)

    Tristan Djajadi, Demi; Hansen, Aleksander R.; Jensen, Anders

    2017-01-01

    in response to hydrothermal pretreatment at different severities are still not sufficiently understood. Results: Potentially important lignocellulosic feedstocks for biorefining, corn stover (Zea mays subsp. mays L.), stalks of Miscanthus × giganteus, and wheat straw (Triticum aestivum L.) were systematically...

  17. On the local politics of administrative decentralization: applying for policy responsibilities in Ecuador

    NARCIS (Netherlands)

    Faust, J.; Harbers, I.

    2012-01-01

    Variation in the behavior and preferences of subnational governments is one of the areas that remain poorly understood by students of comparative decentralization and federalism. Yet, evidence suggests that this variation plays an important role in shaping intergovernmental relations. Ecuador

  18. Complementary role of two evaluation methods in the usability and accessibility evaluation of a non-standard system

    CSIR Research Space (South Africa)

    Adebesin, F

    2010-10-01

    Full Text Available Usability, which is generally defined in terms of application effectiveness, efficiency and user satisfaction, is one of the focus areas of human-computer interaction (HCI). Accessibility is the design of systems that can be perceived, understood...

  19. TTC7A mutations disrupt intestinal epithelial apicobasal polarity

    NARCIS (Netherlands)

    Bigorgne, Amélie E; Farin, Henner F; Lemoine, Roxane; Mahlaoui, Nizar; Lambert, Nathalie; Gil, Marine; Schulz, Ansgar; Philippet, Pierre; Schlesser, Patrick; Abrahamsen, Tore G; Oymar, Knut; Davies, E Graham; Ellingsen, Christian Lycke; Leteurtre, Emmanuelle; Moreau-Massart, Brigitte; Berrebi, Dominique; Bole-Feysot, Christine; Nischke, Patrick; Brousse, Nicole; Fischer, Alain; Clevers, Hans; de Saint Basile, Geneviève

    Multiple intestinal atresia (MIA) is a rare cause of bowel obstruction that is sometimes associated with a combined immunodeficiency (CID), leading to increased susceptibility to infections. The factors underlying this rare disease are poorly understood. We characterized the immunological and

  20. The effect of experienced individuals on navigation by king penguin chick pairs

    NARCIS (Netherlands)

    Nesterova, A.P.; Flack, A.; van Loon, E.E.; Bonadonna, F.; Biro, D.

    2015-01-01

    Group members' individual experience can have important influences when navigating collectively. However, how exactly they structure group travel performance is still not fully understood. This study investigated how navigation and leadership dynamics are affected by the presence of an experienced

  1. Molecular Connections Between Arousal and Metabolic Disease: Orexin and Modafinil

    National Research Council Canada - National Science Library

    Benoit, Stephen C

    2007-01-01

    .... Further, some anti-fatigue pharmacologies (e.g. modafinil) are already used in military settings, though their long-term effects on metabolism or central nervous system function are not well-understood...

  2. Molecular Connections between Arousal and Metabolic Disease: Orexin and Modafinil

    National Research Council Canada - National Science Library

    Benoit, Stephen C

    2008-01-01

    .... Further some anti-fatigue pharmacologies (e.g. modafinil) are already used in military settings though their long-term effects on metabolism or central nervous system function are not well-understood...

  3. Prevention of negative symptom psychopathologies in first-episode schizophrenia

    DEFF Research Database (Denmark)

    Melle, Ingrid; Larsen, Tor K; Haahr, Ulrik

    2008-01-01

    The duration of untreated psychosis (DUP)-the time from onset of psychotic symptoms to the start of adequate treatment--is consistently correlated with better course and outcome, but the mechanisms are poorly understood....

  4. Physical Allergy

    Science.gov (United States)

    ... Infection & Immunity, Faculty of Medical Sciences, University College London, London, UK NOTE: This is the Consumer Version. DOCTORS: ... a physical allergic reaction is not understood. One theory suggests that the physical stimulus changes a protein ...

  5. The impact of soil organism composition and activated carbon on grass-legume competition

    NARCIS (Netherlands)

    Wurst, S.; Van Beersum, S.

    2009-01-01

    Belowground mechanisms involved in plant competition are still poorly understood. Since plant species are differently affected by soil organisms, changes in soil community composition might affect interspecific competition with consequences for plant community structure. We studied whether soil

  6. Framework for systematic indicator selection to assess effects of land management on ecosystem services

    NARCIS (Netherlands)

    Oudenhoven, van A.P.E.; Petz, K.; Alkemade, R.; Hein, L.G.; Groot, de R.S.

    2012-01-01

    Land management is an important factor that affects ecosystem services provision. However, interactions between land management, ecological processes and ecosystem service provision are still not fully understood. Indicators can help to better understand these interactions and provide information

  7. Development of a quantitative model for the mechanism of raveling failure in highway rock slopes using LIDAR.

    Science.gov (United States)

    2013-03-01

    Rock falls on highways while dangerous are unpredictable. Most rock falls are of the raveling type and not conducive to stability : calculations, and even the failure mechanisms are not well understood. LIDAR (LIght Detection And Ranging) has been sh...

  8. Development of Novel Two-Photon Absorbing Chromophores

    National Research Council Canada - National Science Library

    Cooper, Thomas M; Heinrichs, James; Tan, Loon-Seng; Urbas, Augustine M; Fleitz, Paul A; Rogers, Joy E; Slagle, Jonathan E; McLean, Daniel G; Sutherland, Richard L; Brant, Mark

    2006-01-01

    There has been much interest in the development of two-photon absorbing materials and many efforts to understand the nonlinear absorption properties of these dyes, but this area is still not well understood...

  9. Cell-specific vacuolar calcium storage mediated by "CAX1" regulates apoplastic calcium concentration, gas exchange, and plant productivity in "Arabidopsis"

    Science.gov (United States)

    The physiological role and mechanism of nutrient storage within vacuoles of specific cell types is poorly understood. Transcript profiles from "Arabidopsis thaliana" leaf cells differing in calcium concentration ([Ca], epidermis 60 mM) were compared using a microarray screen...

  10. Leonardo da Vinci and the Downburst.

    Science.gov (United States)

    Gedzelman, Stanley David

    1990-05-01

    Evidence from the drawings, experiments, and writings of Leonardo da Vinci are presented to demonstrate that da Vinci recognized and, possibly, discovered the downburst and understood its associated airflow. Other early references to vortex flows resembling downbursts are mentioned.

  11. The general sociometer shame: Positive interpersonal consequences of an ugly emotion

    NARCIS (Netherlands)

    I.E. de Hooge (Ilona)

    2014-01-01

    markdownabstract__Abstract__ For decades, shame has been understood as a negative, self-conscious feeling with mostly negative interpersonal consequences. As a result, shame is currently perceived as an ugly emotion that motivates social withdrawal, avoidance, and inhibition. The

  12. A functional role for WNT-5A in driving airway myocyte proliferation

    NARCIS (Netherlands)

    Koopmans, Tim; Kumawat, Kuldeep; Van Den Berge, Maarten; Meurs, Herman; Gosens, Reinoud

    2013-01-01

    Increased airway smooth muscle (ASM) mass is a common pathological feature associated with chronic airway diseases, notably asthma. The mechanisms, however, remain poorly understood. The WNT (Wingless/integrase-1) signaling pathway has been implicated in various proliferative diseases, including

  13. Does social distinction contribute to socioeconomic inequalities in diet: The case of 'superfoods' consumption

    NARCIS (Netherlands)

    J. Oude Groeniger (Joost); F.J. van Lenthe (Frank); M.A. Beenackers (Marielle); C.B.M. Kamphuis (Carlijn)

    2017-01-01

    markdownabstract_Background:_ The key mechanisms underlying socioeconomic inequalities in dietary intake are still poorly understood, hampering the development of interventions. An important, but sparsely mentioned mechanism is that of 'social distinction', whereby those in a higher socioeconomic

  14. A Surface Analytical Study of the Attachment of Bacteria to Metal Surfaces

    National Research Council Canada - National Science Library

    French, Glenn

    1998-01-01

    ...) and an exopolymer extracted from the marine bacterium Delaya marina. Although organic acids tend to be weak acids and have a relatively low ionic conductivity they are environmentally common and the effects on corrosion of such acids are poorly understood...

  15. Impact of long-term N, P, K, and NPK fertilization on the composition and potential functions of the bacterial community in grassland soil

    NARCIS (Netherlands)

    Pan, Y.; Cassman, N.; Hollander, de M.; Mendes, L.W.; Korevaar, H.; Geerts, R.H.E.M.; Veen, van J.A.; Kuramae, E.E.

    2014-01-01

    Soil abiotic and biotic interactions govern important ecosystem processes. However, the mechanisms behind these interactions are complex, and the links between specific environmental factors, microbial community structures, and functions are not well understood. Here, we applied DNA shotgun

  16. Identification of Two Suppressors of CSG2 Calcium Sensitivity, SCS7 and SUR2, as Genes Encoding Hydroxylases of the Sphingolipid Biosynthetic Pathway of Saccharomyces cerevisiae

    National Research Council Canada - National Science Library

    Haak, Dale A

    1997-01-01

    .... The biochemical significance of much of this structural variability is not well understood. The sphingolipids of the yeast Saccharomyces cerevisiae undergo the a-hydroxylation of the very long chain fatty acid (VLCFA...

  17. Textural Segmentation of High-Resolution Sidescan Sonar Images

    National Research Council Canada - National Science Library

    Kalcic, Maria; Bibee, Dale

    1995-01-01

    .... The high resolution of the 455 kHz sonar imagery also provides much information about the surficial bottom sediments, however their acoustic scattering properties are not well understood at high frequencies...

  18. Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner

    NARCIS (Netherlands)

    Gupta, V.K.; Scheunemann, L.; Eisenberg, T.; Mertel, S.; Bhukel, A.; Koemans, T.S.; Kramer, J.M.; Liu, K.S.; Schroeder, S.; Stunnenberg, H.G.; Sinner, F.; Magnes, C.; Pieber, T.R.; Dipt, S.; Fiala, A.; Schenck, A.; Schwaerzel, M.; Madeo, F.; Sigrist, S.J.

    2013-01-01

    Age-dependent memory impairment is known to occur in several organisms, including Drosophila, mouse and human. However, the fundamental cellular mechanisms that underlie these impairments are still poorly understood, effectively hampering the development of pharmacological strategies to treat the

  19. Design Of A Laboratory Set-up For Evaluating Structural Strength Of Deteriorated Concrete Sewer Pipes

    NARCIS (Netherlands)

    Stanic, N.; Salet, T.; Langeveld, J.G.; Clemens, F.H.L.R.

    2014-01-01

    The principle of structural behaviour of buried concrete pipes is fairly understood, except for how material deterioration affects structural behaviour and performance. Consequently, information on the structural behaviour of deteriorated sewer pipes will contribute to better understanding of the

  20. Physiological benefits of nectar-feeding by a predatory beetle

    Science.gov (United States)

    Extrafloral nectar is an important food source for many animals, including predatory lady beetles (Coleoptera: Coccinellidae), although the physiological benefits of nectar consumption are poorly understood for most consumers. Under laboratory conditions, we confined new females of Coleomegilla macu...

  1. 76 FR 2088 - Proposed Information Collection; Comment Request

    Science.gov (United States)

    2011-01-12

    ..., reporting burden (time and financial resources) is minimized, collection instruments are clearly understood... Financial Management Survey collects information from new grantees about their financial management systems... CORPORATION FOR NATIONAL AND COMMUNITY SERVICE Proposed Information Collection; Comment Request...

  2. 77 FR 55229 - National Farmworker Jobs Program (NFJP) Information Collection Forms; Comment Request for Regular...

    Science.gov (United States)

    2012-09-07

    ..., reporting burden (time and financial resources) is minimized, collection instruments are clearly understood...) Information Collection Forms; Comment Request for Regular Extension of Approval (With Revisions) AGENCY: Employment and Training Administration (ETA), Department of Labor. ACTION: Notice. Overview Information...

  3. Direct and indirect effects of resource quality on food web structure

    NARCIS (Netherlands)

    Bukovinszky, T.; Veen, van F.; Jongema, Y.; Dicke, M.

    2008-01-01

    The diversity and complexity of food webs (the networks of feeding relationships within an ecological community) are considered to be important factors determining ecosystem function and stability. However, the biological processes driving these factors are poorly understood. Resource quality

  4. Environmental enteric dysfunction is associated with carnitine deficiency and altered fatty acid oxidation

    Science.gov (United States)

    Environmental enteric dysfunction (EED), a condition characterized by small intestine inflammation and abnormal gut permeability, is widespread in children in developing countries and a major cause of growth failure. The pathophysiology of EED remains poorly understood. We measured serum metabolite...

  5. Body fat distribution and inflammation among obese older adults with and without metabolic syndrome

    NARCIS (Netherlands)

    Koster, A.; Stenholm, S.; Alley, D.E.; Kim, L.J.; Simonsick, E.M.; Kanaya, A.M.; Visser, M.; Houston, D.K.; Nicklas, B.J.; Tylavsky, F.A.; Satterfield, S.; Goodpaster, B.H.; Ferrucci, L.; Harris, T.B.

    2010-01-01

    The protective mechanisms by which some obese individuals escape the detrimental metabolic consequences of obesity are not understood. This study examined differences in body fat distribution and adipocytokines in obese older persons with and without metabolic syndrome. Additionally, we examined

  6. Impaired peri-nidal cerebrovascular reserve in seizure patients with brain arteriovenous malformations

    NARCIS (Netherlands)

    Fierstra, Jorn; Conklin, John; Krings, Timo; Slessarev, Marat; Han, Jay S.; Fisher, Joseph A.; terBrugge, Karel; Wallace, M. Christopher; Tymianski, Michael; Mikulis, David J.

    Epileptic seizures are a common presentation in patients with newly diagnosed brain arteriovenous malformations, but the pathophysiological mechanisms causing the seizures remain poorly understood. We used magnetic resonance imaging-based quantitative cerebrovascular reactivity mapping and

  7. Report of the international consensus development conference on female sexual dysfunction: definitions and classifications

    NARCIS (Netherlands)

    Basson, R.; Berman, J.; Burnett, A.; Derogatis, L.; Ferguson, D.; Fourcroy, J.; Goldstein, I.; Graziottin, A.; Heiman, J.; Laan, E.; Leiblum, S.; Padma-Nathan, H.; Rosen, R.; Segraves, K.; Segraves, R. T.; Shabsigh, R.; Sipski, M.; Wagner, G.; Whipple, B.

    2000-01-01

    PURPOSE: Female sexual dysfunction is highly prevalent but not well defined or understood. We evaluated and revised existing definitions and classifications of female sexual dysfunction. MATERIALS AND METHODS: An interdisciplinary consensus conference panel consisting of 19 experts in female sexual

  8. Evolution and connectivity in the world-wide migration system of the mallard: Inferences from mitochondrial DNA

    NARCIS (Netherlands)

    Kraus, R.H.S.; Zeddeman, A.; Hooft, van W.F.; Sartakov, D.; Soloviev, S.A.; Ydenberg, R.C.; Prins, H.H.T.

    2011-01-01

    Main waterfowl migration systems are well understood through ringing activities. However, in mallards (Anas platyrhynchos) ringing studies suggest deviations from general migratory trends and traditions in waterfowl. Furthermore, surprisingly little is known about the population genetic structure of

  9. The effect of three-dimensional geometrical changes during adolescent growth on the biomechanics of a spinal motion segment

    NARCIS (Netherlands)

    Homminga, J.; Hekman, E. E. G.; Veldhuizen, A. G.; Verkerke, G. J.; Meijer, G.

    2010-01-01

    During adolescent growth, vertebrae and intervertebral discs undergo various geometrical changes. Although such changes in geometry are well known, their effects on spinal stiffness remains poorly understood. However, this understanding is essential in the treatment of spinal abnormalities during

  10. Contemporary coronary intervention trialconduct : addressing the 4P's: Patency, Perfusion, Performance and Prevention

    NARCIS (Netherlands)

    P. Vranckx (Pascal)

    2012-01-01

    textabstractThe concern about how the effects of pharmacologic as well as device therapies are understood in clinical practice requires attention to the methods of randomized clinical trials, including the selection of meaningful clinical endpoints.

  11. Fructose, high fructose corn syrup, sucrose, and non-alcoholic liver disease

    Science.gov (United States)

    Nonalcoholic fatty liver disease (NAFLD), formerly called nonalcoholic steatohepatitis, is characterized by hepatic steatosis and abnormal triglyceride accumulation in liver cells. Its etiology, pathophysiology, and pathogenesis are still poorly understood. Some have suggested that the increased in...

  12. High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas.

    NARCIS (Netherlands)

    Diosdado, B.; Buffart, T.E.; Watkins, R.; Carvalho, B.; Ylstra, B.; Tijssen, M.; Bolijn, A.S.; Lewis, F.; Maude, K.; Verbeke, C.; Nagtegaal, I.D.; Grabsch, H.; Mulder, C.J.; Quirke, P.; Howdle, P.; Meijer, G.A.

    2010-01-01

    PURPOSE: The molecular pathogenesis of small intestinal adenocarcinomas is not well understood. Understanding the molecular characteristics of small bowel adenocarcinoma may lead to more effective patient treatment. EXPERIMENTAL DESIGN: Forty-eight small bowel adenocarcinomas (33 non-celiac disease

  13. The prevalence and causes of autistic spectrum disorders.

    Science.gov (United States)

    Hainsworth, Terry

    Autism and autistic spectrum disorders are still relatively poorly understood. This article outlines the results of new research into the prevalence of autism and into the causes of the condition and highlights implications for nurses from the findings.

  14. Cognitive decline in Parkinson’s disease is associated with slowing of resting-state brain activity: a longitudinal study

    NARCIS (Netherlands)

    Olde Dubbelink, K.T.E.; Stoffers, D.; Deijen, J.B.; Twisk, J.W.R.; Stam, C.J.; Berendse, H.W.

    2013-01-01

    The pathophysiological mechanisms of Parkinson's disease (PD)-related dementia (PDD) are still poorly understood. Previous studies using electroencephalography (EEG) and magnetoencephalography (MEG) have demonstrated widespread slowing of oscillatory brain activity as a neurophysiological

  15. In-Flight Medical Incapacitation and Impairment of U.S. Airline Pilots: 1993 to 1998

    National Research Council Canada - National Science Library

    DeJohn, Charles

    2004-01-01

    .... The importance of in-flight medical incapacitation and impairment can be better understood when it is realized that each in-flight medical incapacitation or impairment could potentially lead to an aircraft accident...

  16. Tidal impact on the division of river discharge and distributary channels in the Mahakam Delta

    NARCIS (Netherlands)

    Sassi, M.G.; Hoitink, A.J.F.; Brye, de B.; Vermeulen, B.; Deleersnijder, E.

    2011-01-01

    Bifurcations in tidally influenced deltas distribute river discharge over downstream channels, asserting a strong control over terrestrial runoff to the coastal ocean. Whereas the mechanics of river bifurcations is well-understood, junctions in tidal channels have received comparatively little

  17. Lower Ipsilateral Hippocampal Integrity after Ischemic Stroke in Young Adults: A Long-Term Follow-Up Study

    NARCIS (Netherlands)

    Schaapsmeerders, P.; Tuladhar, A.M.; Maaijwee, N.A.M.M.; Rutten-Jacobs, L.C.A.; Arntz, R.M.; Schoonderwaldt, H.C.; Dorresteijn, L.D.A.; Dijk, E.J. van; Kessels, R.P.C.; Leeuw, H.F. de

    2015-01-01

    Background and purpose Memory impairment after stroke is poorly understood as stroke rarely occurs in the hippocampus. Previous studies have observed smaller ipsilateral hippocampal volumes after stroke compared with controls. Possibly, these findings on macroscopic level are not the first

  18. Lower Ipsilateral Hippocampal Integrity after Ischemic Stroke in Young Adults: A Long-Term Follow-Up Study

    NARCIS (Netherlands)

    Schaapsmeerders, P.; Tuladhar, A.M.; Maaijwee, N.A.M.M.; Rutten-Jacobs, L.C.A.; Arntz, R.M.; Schoonderwaldt, H.C.; Dorresteijn, L.D.; Dijk, E.J. van; Kessels, R.P.C.; Leeuw, F.E. de

    2015-01-01

    BACKGROUND AND PURPOSE: Memory impairment after stroke is poorly understood as stroke rarely occurs in the hippocampus. Previous studies have observed smaller ipsilateral hippocampal volumes after stroke compared with controls. Possibly, these findings on macroscopic level are not the first

  19. Ipsilateral hippocampal atrophy is associated with long-term memory dysfunction after ischemic stroke in young adults

    NARCIS (Netherlands)

    Schaapsmeerders, P.; Uden, I.W.M. van; Tuladhar, A.M.; Maaijwee, N.A.M.M.; Dijk, E.J. van; Rutten-Jacobs, L.C.A.; Arntz, R.M.; Schoonderwaldt, H.C.; Dorresteijn, L.D.A.; Leeuw, H.F. de; Kessels, R.P.C.

    2015-01-01

    Memory impairment after stroke in young adults is poorly understood. In elderly stroke survivors memory impairments and the concomitant loss of hippocampal volume are usually explained by coexisting neurodegenerative disease (e.g., amyloid pathology) in interaction with stroke. However,

  20. Comet Hitchhiker: Harvesting Kinetic Energy from Small Bodies to Enable Fast and Low-Cost Deep Space Exploration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This idea can be intuitively understood by the analogy of fishing. Imagine a fisherman on a small boat tries to catch a big fish that runs at a high relative speed....

  1. Optimized NSAIDs for Breast Cancer Prevention

    National Research Council Canada - National Science Library

    Carson, Dennis A

    2006-01-01

    .... Also, how these agents prevent breastcancer is not understood. This project will develop an optimized NSAID for breast cancer prevention that can betaken safely at high doses, and will determine its mechanisms of action...

  2. Optimized NSAIDS for Breast Cancer Prevention

    National Research Council Canada - National Science Library

    Carson, Dennis A

    2005-01-01

    .... Also, how these agents prevent breast cancer is not understood. This project will develop an optimized NSAID for breast cancer prevention that can be taken safely at high doses, and will determine its mechanisms of action...

  3. How bird clades diversify in response to climatic and geographic factors

    NARCIS (Netherlands)

    Rodríguez-Castañeda, Genoveva; Hof, Anouschka R.; Jansson, Roland

    2017-01-01

    While the environmental correlates of global patterns in standing species richness are well understood, it is poorly known which environmental factors promote diversification (speciation minus extinction) in clades. We tested several hypotheses for how geographic and climatic variables should affect

  4. Information Warfare, Cyber-Terrorism and Community Values

    National Research Council Canada - National Science Library

    Moore, Joe

    2002-01-01

    ... and interconnected global information infrastructure. These vulnerabilities, when exploited by those who would target civilians in order to inspire widespread fear in hopes of accomplishing a political agenda, can be understood as cyberterrorism...

  5. Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

    NARCIS (Netherlands)

    Manoussaka, Maria S.; Berry, Neil; Ferguson, Deborah; Stebbings, Richard; Robinson, Mark; Ham, Claire; Page, Mark; Li, Bo; Das, Atze T.; Berkhout, Ben; Almond, Neil; Cranage, Martin P.

    2013-01-01

    Live attenuated SIV induces potent protection against superinfection with virulent virus; however the mechanism of this vaccine effect is poorly understood. Such knowledge is important for the development of clinically acceptable vaccine modalities against HIV. Using a novel, doxycycline dependent,

  6. Sapling performance along resource gradients drives tree species distributions within and across tropical forests

    NARCIS (Netherlands)

    Sterck, F.J.; Markesteijn, L.; Toledo, M.; Schieving, F.; Poorter, L.

    2014-01-01

    Niche differentiation is a major hypothesized determinant of species distributions, but its practical importance is heavily debated and its underlying mechanisms are poorly understood. Trait-based approaches have been used to infer niche differentiation and predict species distributions. For

  7. Interpretation of Climate Change and Agricultural Adaptations by Local Household Farmers: a Case Study at Bin County, Northeast China

    NARCIS (Netherlands)

    Yu, Q.; Wu, W.; Liu, Z.; Verburg, P.H.; Xia, T.; Yang, P.; Lu, Z.; You, L.; Tang, H.

    2014-01-01

    Although climate change impacts and agricultural adaptations have been studied extensively, how smallholder farmers perceive climate change and adapt their agricultural activities is poorly understood. Survey-based data (presents farmers' personal perceptions and adaptations to climate change)

  8. Taxonomic novelties in Plantago section Virginica (Plantaginaceae) and an updated identification key

    DEFF Research Database (Denmark)

    Hassemer, Gustavo; Trevisan, Rafael; Meudt, Heidi

    2015-01-01

    This study raises two rather poorly understood subspecies to the rank of species, and revalidates two subspecies in Plantago (Plantaginaceae) section Virginica. Plantago napiformis, formerly P. tomentosa subsp. napiformis, is an uncommon species from grasslands in northeastern Argentina, southern...

  9. The metabolic syndrome, cardiopulmonary fitness, and subcutaneous trunk fat as independent determinants of arterial stiffness: the Amsterdam Growth and Health Longitudinal Study

    NARCIS (Netherlands)

    Ferreira, I.; Henry, R.M.A.; Twisk, J.W.R.; van Mechelen, W.; Kemper, H.C.G.; Stehouwer, C.D.A.

    2005-01-01

    Background: The mechanisms that link the metabolic syndrome to increased cardiovascular risk are incompletely understood, especially in young people. We therefore examined whether the metabolic syndrome was associated with arterial stiffness and whether any such associations were independent of

  10. Socio-economic status and self-reported tuberculosis: A multilevel analysis in a low-income township in the eastern cape, South Africa

    NARCIS (Netherlands)

    J.M. Cramm (Jane); A.H.E. Koolman (Xander); V. Møller (Valerie); A.P. Nieboer (Anna)

    2011-01-01

    textabstractFew studies have investigated the interplay of multiple factors affecting the prevalence of tuberculosis in developing countries. The compositional and contextual factors that affect health and disease patterns must be fully understood to successfully control tuberculosis. Experience

  11. A microRNA signature associated with chondrogenic lineage ...

    Indian Academy of Sciences (India)

    2012-08-09

    -376) with chondrocyte targets. (such as TGFbR, MAP3K, ... NAs and their functions in skeletal development are poorly understood. Likewise, little is ... eBioscience, San Diego, USA), CD34 (PE-conjugated). (Dako, Glostrup ...

  12. DEVELOPMENT OF AQUATIC MODELS FOR TESTING THE RELATIONSHIP BETWEEN GENETIC DIVERSITY AND POPULATION EXTINCTION RISK

    Science.gov (United States)

    The relationship between population adaptive potential and extinction risk in a changing environment is not well understood. Although the expectation is that genetic diversity is directly related to the capacity of populations to adapt, the statistical and predictive aspects of ...

  13. Effect of scanning speed and powder flow rate on the evolving properties of laser metal deposited Ti-6Al-4V/Cu composites

    CSIR Research Space (South Africa)

    Erinosho, MF

    2016-01-01

    Full Text Available In laser metal deposition (LMD), good bonding between two similar or dissimilar materials can be achieved if the interrelationships between the processing parameters are well understood. LMD was conducted by varying the scanning speed and keeping...

  14. An empirical approach to the mathematical values of problem choice and argumentation

    DEFF Research Database (Denmark)

    Johansen, Mikkel Willum; Misfeldt, Morten

    2016-01-01

    specifically, we will analyze the values connected to mathematicians’ choice of problems and their choice of argumentative style when communicating their results. We suggest that these two situations can be understood as relating to the three mathematical values: recognizability, formalizability...

  15. Analysis of the chemical and physical properties of combustion aerosols: State of the art.

    Science.gov (United States)

    The impact of combustion aerosols on human health is well documented byepidemiological studies, however the effect of low concentrations of ultrafineparticles on the human lung are not yet fully understood. With the advent ofnovel measurement technologies for simultaneous charact...

  16. Adaptations in pre- and postsynaptic 5-HT(1A) receptor function and cocaine supersensitivity in serotonin transporter knockout rats

    NARCIS (Netherlands)

    Homberg, Judith R; De Boer, Sietse F; Raasø, Halfdan S; Olivier, Jocelien D A; Verheul, Mark; Ronken, Eric; Cools, Alexander R; Ellenbroek, Bart A; Schoffelmeer, Anton N M; Vanderschuren, Louk J M J; De Vries, Taco J; Cuppen, Edwin

    2008-01-01

    RATIONALE: While individual differences in vulnerability to psychostimulants have been largely attributed to dopaminergic neurotransmission, the role of serotonin is not fully understood. OBJECTIVES: To study the rewarding and motivational properties of cocaine in the serotonin transporter knockout

  17. Logic an introductory course

    CERN Document Server

    Newton-Smith, WH

    2003-01-01

    A complete introduction to logic for first-year university students with no background in logic, philosophy or mathematics. In easily understood steps it shows the mechanics of the formal analysis of arguments.

  18. Profiling DNA damage response following mitotic perturbations

    DEFF Research Database (Denmark)

    Pedersen, Ronni Sølvhøi; Karemore, Gopal; Gudjonsson, Thorkell

    2016-01-01

    Genome integrity relies on precise coordination between DNA replication and chromosome segregation. Whereas replication stress attracted much attention, the consequences of mitotic perturbations for genome integrity are less understood. Here, we knockdown 47 validated mitotic regulators to show t...

  19. Behavioral Response of Blue Whales to Active Signals

    National Research Council Canada - National Science Library

    Aburto, A

    1997-01-01

    The effects of low frequency sound on marine mammals are not well understood. Although baleen whales are known to produce low frequency sounds, very little is known about their auditory sensitivity...

  20. Effects of immune supplementation and immune challenge on bacterial assemblages in the avian cloaca

    NARCIS (Netherlands)

    Matson, Kevin D.; Versteegh, Maaike A.; van der Velde, Marco; Tieleman, B. Irene

    Relationships between avian physiology and bacterial assemblages in the cloaca are poorly understood. We used molecular techniques to analyze cloacal swabs from pigeons that were subjected to two immunological manipulations: lysozyme supplementation and endotoxin challenge. From the swabs, we

  1. Forensic Science Education and Educational Requirements for Forensic Scientists.

    Science.gov (United States)

    Gaensslen, Robert E.

    2002-01-01

    Focuses on criminalistics, which can be understood to mean the activities and specialty areas characteristic of most municipal, county, or state forensic science laboratories in the United States. (DDR)

  2. Submarine groundwater discharge at Kahana Bay, Oahu, 1997-2001: in situ CTD and water chemistry tracer data (NODC Accession 0011399)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Submarine groundwater discharge (SGD) is neither well understood nor commonly investigated in Hawaii, but it is recognized as a potential pollution source to coastal...

  3. Civil-Military Relations in Latin America: The Hedgehog and the Fox Revisited

    National Research Council Canada - National Science Library

    Bruneau, Thomas C

    2005-01-01

    .... Based on the academic literature and the author's experience in Latin America and other regions, this article suggests that civil-military relations are best understood in terms of effectiveness...

  4. Influence of the workplace on learning physical examination skills

    NARCIS (Netherlands)

    Duvivier, R.; Stalmeijer, R.; Dalen, J. Van; Vleuten, C.P.M. van der; Scherpbier, A.

    2014-01-01

    BACKGROUND: Hospital clerkships are considered crucial for acquiring competencies such as diagnostic reasoning and clinical skills. The actual learning process in the hospital remains poorly understood. This study investigates how students learn clinical skills in workplaces and factors affecting

  5. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases

    DEFF Research Database (Denmark)

    Ferrari, Raffaele; Wang, Yunpeng; Vandrovcova, Jana

    2017-01-01

    BACKGROUND: Clinical, pathological and genetic overlap between sporadic frontotemporal dementia (FTD), Alzheimer's disease (AD) and Parkinson's disease (PD) has been suggested; however, the relationship between these disorders is still not well understood. Here we evaluated genetic overlap betwee...

  6. Effects of ecosystem development on benthic secondary production in restored and created mangrove habitats

    Science.gov (United States)

    Wetland creation, enhancement, and restoration activities are commonly implemented to compensate for wetland loss or degradation. However, functional equivalence in restored and created wetland habitats is often poorly understood. In estuarine habitats, changes in habitat qualit...

  7. Ecosystem Development after Mangrove Wetland Creation: Plant-Soil Change across a 20-year Chronosequence

    Science.gov (United States)

    Mangrove wetland restoration and creation efforts are increasingly proposed as mechanisms to compensate for mangrove wetland loss. However, ecosystem development and functional equivalence in restored and created mangrove wetlands is poorly understood. We compared a 20-yr chrono...

  8. A Driving Simulator Evaluation of Red Arrows and Flashing Yellow Arrows in Right-Turn Applications : Establishing the Foundation for Future Research

    Science.gov (United States)

    2017-11-01

    Driver understanding of flashing yellow arrow (FYA) indications for left turns has been studied extensively; however, the use of FYA for right-turn applications is an area that needs to be better understood through evaluations focused on actual drive...

  9. Evaluating the relationship between the driver and roadway to address rural intersection safety using the SHRP 2 naturalistic driving study data.

    Science.gov (United States)

    2016-02-01

    Rural intersections account for 30% of crashes in rural areas and 6% of all fatal crashes, representing a significant but poorly : understood safety problem. Transportation agencies have traditionally implemented countermeasures to address rural inte...

  10. A Strategic Governance Review for Multi-Organizational Systems of Education, Training, and Professional Development

    National Research Council Canada - National Science Library

    Daley, Glenn

    2003-01-01

    ...) through both DoD and non-DoD providers. This network of ET&D providers and users constitutes a multi-organizational, multi-stakeholder system that is at present loosely coordinated and incompletely understood...

  11. Responses of the Lichen Photobiont Trebouxia erici to Desiccation and Rehydration (II) Proteomics

    Science.gov (United States)

    Lichen desiccation tolerance is associated with cellular protection mechanisms directed against the oxidative stress produced during dehydration and/or rehydration, however, these mechanisms are not well understood. In other poikilohydric organisms, changes in the synthesis of proteins have bee...

  12. Quantitative aspects of metabolic organization; a discussion of concepts.

    NARCIS (Netherlands)

    Kooijman, S.A.L.M.

    2001-01-01

    Metabolic organization of individual organisms follows simple quantitative rules that can be understood from basic physical chemical principles. Dynamic energy budget (DEB) theory identifies these rules, which quantify how individuals acquire and use energy and nutrients. The theory provides

  13. The Arabidopsis sickle mutant exhibits altered circadian clock responses to cool tempatures and tempature-dependent alternative splicing

    Science.gov (United States)

    The circadian clock allows plants to anticipate and respond to daily changes in ambient temperature. Mechanisms establishing the timing of circadian rhythms in Arabidopsis thaliana through temperature entrainment remain unclear. Also incompletely understood is the temperature compensation mechanism ...

  14. Mitochondrial Reprogramming Induced by CaMKII delta Mediates Hypertrophy Decompensation

    NARCIS (Netherlands)

    Westenbrink, B. Daan; Ling, Haiyun; Divakaruni, Ajit S.; Gray, Charles B. B.; Zambon, Alexander C.; Dalton, Nancy D.; Peterson, Kirk L.; Gu, Yusu; Matkovich, Scot J.; Murphy, Anne N.; Miyamoto, Shigeki; Dorn, Gerald W.; Brown, Joan Heller

    2015-01-01

    Rationale: Sustained activation of Gq transgenic (Gq) signaling during pressure overload causes cardiac hypertrophy that ultimately progresses to dilated cardiomyopathy. The molecular events that drive hypertrophy decompensation are incompletely understood. Ca2+/calmodulin-dependent protein kinase

  15. Development of Facial Emotion Recognition in Childhood : Age-related Differences in a Shortened Version of the Facial Expressions of Emotion - Stimuli and Tests

    NARCIS (Netherlands)

    Coenen, Maraike; Aarnoudse, Ceciel; Huitema, Rients; Braams, Olga; Veenstra, Wencke S.

    2013-01-01

    Introduction Facial emotion recognition is essential for social interaction. The development of emotion recognition abilities is not yet entirely understood (Tonks et al. 2007). Facial emotion recognition emerges gradually, with happiness recognized earliest (Herba & Phillips, 2004). The recognition

  16. The Influence of Ergonomic Interventions on Employee Stress and Physical Symptoms

    National Research Council Canada - National Science Library

    Joseph, Kurt

    1999-01-01

    ...). While the etiologic mechanisms are poorly understood, there is increasing evidence that psychosocial risk factors related to the job and work environment play a role in the development of work-related MSDs...

  17. Circulating sex hormones and breast cancer risk factors in postmenopausal women : reanalysis of 13 studies

    NARCIS (Netherlands)

    Key, T. J.; Appleby, P. N.; Reeves, G. K.; Roddam, A. W.; Helzlsouer, K. J.; Alberg, A. J.; Rollison, D. E.; Dorgan, J. F.; Brinton, L. A.; Overvad, K.; Kaaks, R.; Trichopoulou, A.; Clavel-Chapelon, F.; Panico, S.; Duell, E. J.; Peeters, P. H. M.; Rinaldi, S.; Riboli, E.; Fentiman, I. S.; Dowsett, M.; Manjer, J.; Lenner, P.; Hallmans, G.; Baglietto, L.; English, D. R.; Giles, G. G.; Hopper, J. L.; Severi, G.; Morris, H. A.; Koenig, K.; Zeleniuch-Jacquotte, A.; Arslan, A. A.; Toniolo, P.; Shore, R. E.; Krogh, V.; Micheli, A.; Berrino, F.; Muti, P.; Barrett-Connor, E.; Laughlin, G. A.; Kabuto, M.; Akiba, S.; Stevens, R. G.; Neriishi, K.; Land, C. E.; Cauley, J. A.; Lui, Li Yung; Cummings, Steven R.; Gunter, M. J.; Rohan, T. E.; Strickler, H. D.

    2011-01-01

    BACKGROUND: Breast cancer risk for postmenopausal women is positively associated with circulating concentrations of oestrogens and androgens, but the determinants of these hormones are not well understood. METHODS: Cross-sectional analyses of breast cancer risk factors and circulating hormone

  18. Functional characterisation of three zinc transporters in Thlaspi caerulescens

    NARCIS (Netherlands)

    Talukdar, S.

    2007-01-01

    Heavy metal hyperaccumulation in plants is a poorly understood phenomenon. Transmembrane metal transporters are assumed to play a key role in this process. In the research described in this thesis, genes encoding Zn transporters of Thlaspi

  19. Population dynamics of potato cyst nematodes and associated damage to potato

    NARCIS (Netherlands)

    Schans, J.

    1993-01-01

    Population dynamics of potato cyst nematodes (PCN; Globoderarostochiensis (Woll.) Skarbilovich and G. pallida Stone) and their interactions with potato plants are insufficiently understood to explain variations of population

  20. Secondary organic aerosol formation from fossil fuel sources contribute majority of summertime organic mass at Bakersfield

    Science.gov (United States)

    Secondary organic aerosols (SOA), known to form in the atmosphere from oxidation of volatile organic compounds (VOCs) emitted by anthropogenic and biogenic sources, are a poorly understood but substantial component of atmospheric particles. In this study, we examined the chemic...

  1. GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans

    DEFF Research Database (Denmark)

    Gasbjerg, Lærke S; Christensen, Mikkel B; Hartmann, Bolette

    2018-01-01

    AIMS/HYPOTHESIS: Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted postprandially from enteroendocrine K cells, but despite therapeutically interesting effects, GIP physiology in humans remains incompletely understood. Progress in this field could be facilitated b...

  2. All is not lost: Deriving a top-down mass budget of plastic at sea.

    NARCIS (Netherlands)

    Koelmans, Bart; Kooi, Merel; Law, Kara Lavender; Sebille, van Erik

    2017-01-01

    Understanding the global mass inventory is one of the main challenges in present research on plastic marine debris. Especially the fragmentation and vertical transport processes of oceanic plastic are poorly understood. However, whereas fragmentation rates are unknown, information on plastic

  3. Cellular Clocks : Coupled Circadian Dispatch and Cell Division Cycles

    NARCIS (Netherlands)

    Merrow, Martha; Roenneberg, Till

    2004-01-01

    Gating of cell division by the circadian clock is well known, yet its mechanism is little understood. Genetically tractable model systems have led to new hypotheses and questions concerning the coupling of these two cellular cycles.

  4. Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health

    NARCIS (Netherlands)

    Dilger, Karin; Hohenester, Simon; Winkler-Budenhofer, Ursula; Bastiaansen, Barbara A. J.; Schaap, Frank G.; Rust, Christian; Beuers, Ulrich

    2012-01-01

    Background & Aims: Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood. Its adequate biliary enrichment is considered mandatory for therapeutic efficacy. However, precise

  5. Mate-guarding intensity increases with breeding synchrony in the colonial fairy martin, Petrochelidon ariel

    NARCIS (Netherlands)

    Hammers, Martijn; von Engelhardt, Nikolaus; Langmore, Naomi E.; Komdeur, Jan; Griffith, Simon C.; Magrath, Michael J. L.

    Extrapair paternity (EPP) is common in many socially monogamous species, influencing patterns of sexual selection and shaping many aspects of reproductive behaviour. However, factors explaining variation in the occurrence of EPP, both within and between populations, remain poorly understood. One

  6. Interaction of bottom-up and top-down processes in the perception of ambiguous figures

    NARCIS (Netherlands)

    Intaite, Monika; Noreika, Valdas; Soliunas, Alvydas; Falter, Christine M.

    2013-01-01

    Ambiguous figures reverse their appearance during prolonged viewing and can be perceived in two (or more) available interpretations. Both physical stimulus manipulations and cognitive control influence the perception of ambiguous figures, but the underlying mechanisms remain poorly understood. In

  7. Cell biophysics: How to eat on the go

    Science.gov (United States)

    Levine, Herbert

    2016-12-01

    Dendritic cells use components of their cytoskeleton to both move and ingest pieces of infected cells. This competition for protein resources can give rise to a complex set of states that may be understood with an advection-diffusion model.

  8. Contrasting trait responses in plant communities to experimental and geographic variation in precipitation

    DEFF Research Database (Denmark)

    Sandel, Brody Steven; Goldstein, Leah; Kraft, Nathan

    2010-01-01

    Patterns of precipitation are likely to change significantly in the coming century, with important but poorly understood consequences for plant communities. Experimental and correlative studies may provide insight into expected changes, but little research has addressed the degree of concordance ...

  9. AtCHX13 is a plasma membrane K(+) transporter

    Science.gov (United States)

    Potassium (K+) homeostasis is essential for diverse cellular processes, although how various cation transporters collaborate to maintain a suitable K(+) required for growth and development is poorly understood. The Arabidopsis ("Arabidopsis thaliana") genome contains numerous cation:proton antiporte...

  10. AtCHX13 is a plasma membrane K+ transporter

    Science.gov (United States)

    Potassium (K+) homeostasis is essential for diverse cellular processes, although how various cation transporters collaborate to maintain a suitable K+ required for growth and development is poorly understood. The Arabidopsis (Arabidopsis thaliana) genome contains numerous cation:proton antiporters (...

  11. A flower in fruit's clothing: Pollination of jackfruit Artocarpus heterophyllus, Moraceae) by a new species of gall midge, Clinodiplosis ultracrepidata sp. nov. (Diptera: Cecidomyiidae)

    Science.gov (United States)

    Premise of the Research: Jackfruit (Artocarpus heterophyllus, Moraceae) is an emerging but underutilized crop whose pollination is poorly understood. We present a multidimensional investigation of the reproductive biology and chemical ecology of jackfruit and a putative pollinator, Clinodiplosis ult...

  12. Statistical Compilation of the ICT Sector and Policy Analysis | Page 3 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ICTs) continues to widen and deepen, so too does its impact on economic development. However, much work needs to be done before the linkages between economic development and ICTs can be understood in a systematic and meaningful ...

  13. Development of a Failure Theory for Concrete

    Science.gov (United States)

    2012-07-31

    The failure behavior of concrete materials is not completely understood because conventional test methods fail to assess the : material response independent of the sample size and shape. : To study the influence of strength affecting test conditions,...

  14. Ubiquinol Improves Symptoms in Children with Autism

    NARCIS (Netherlands)

    Gvozdjakova, Anna; Kucharska, Jarmila; Ostatnikova, Daniela; Babinska, Katarina; Nakladal, Dalibor; Crane, Fred L.

    2014-01-01

    Background. Autism is a spectrum of neurodevelopmental disorders with manifestation within 3 years after birth. Manifestations of autism include behavior problems (hyperactivity, toys destruction, self-harm, and agression) and sleep and eating disorders. Etiology of autism is poorly understood.

  15. Approaches to and tools for managing environmental conflicts in ...

    African Journals Online (AJOL)

    As coastal environments become excessively anthropocentric, ecological dimensions cannot obviate the impact of human behaviour. Integrated approaches present powerful frameworks for analysing human-environmental conflicts, understood as ecological change, together with human knowledge and practice. Efforts at ...

  16. Indigenous Competition for Control in Bolivia

    National Research Council Canada - National Science Library

    Schmidt, Richard J

    2005-01-01

    .... This thesis argues that the ascendancy of Bolivia's groups can be best understood though the application of organization and social movement theories, and it uses the political economy framework as a backdrop...

  17. Molecular profiling of tumour budding implicates TGFβ-mediated epithelial–mesenchymal transition as a therapeutic target in oral squamous cell carcinoma

    DEFF Research Database (Denmark)

    Jensen, David Hebbelstrup; Dabelsteen, Erik; Specht, Lena

    2015-01-01

    Although tumour budding is an adverse prognostic factor for many cancer types, the molecular mechanisms governing this phenomenon are incompletely understood. Therefore, understanding the molecular basis of tumour budding may provide new therapeutic and diagnostic options. We employ digital image...

  18. Cardiomyopathy confers susceptibility to particulate matter-induced oxidative stress, vagal dominance, arrhythmia, pulmonary inflammation in heart failure-prone rats

    Science.gov (United States)

    Acute exposure to ambient fine particulate matter (PM2.5) is tied to cardiovascular morbidity and mortality, especially among those with prior cardiac injury. The mechanisms and pathophysiologic events precipitating these outcomes remain poorly understood but may involve inflamm...

  19. Single Enzyme Studies Reveal the Existence of Discrete Functional States for Monomeric Enzymes and How They Are “Selected” upon Allosteric Regulation

    DEFF Research Database (Denmark)

    Hatzakis, Nikos S.; Wei, Li; Jørgensen, Sune Klamer

    2012-01-01

    Allosteric regulation of enzymatic activity forms the basis for controlling a plethora of vital cellular processes. While the mechanism underlying regulation of multimeric enzymes is generally well understood and proposed to primarily operate via conformational selection, the mechanism underlying...

  20. The effects of glucocorticoids on feeding behavior in rats

    NARCIS (Netherlands)

    la Fleur, Susanne E.

    2006-01-01

    Glucocorticoids have major effects on food intake, however, the underlying mechanisms are poorly understood. This article highlights data on the changes that occur when glucocorticoids are removed by adrenalectomy, and the effects of central and systemic administered glucocorticoids on feeding

  1. In situ TEM studies of the shape evolution of Pd nanocrystals under oxygen and hydrogen environments at atmospheric pressure.

    Science.gov (United States)

    Zhang, Xun; Meng, Jun; Zhu, Beien; Yu, Jian; Zou, Shihui; Zhang, Ze; Gao, Yi; Wang, Yong

    2017-12-12

    We demonstrate an atomic scale TEM observation of shape evolutions of Pd nanocrystals under oxygen and hydrogen environments at atmospheric pressure. Combined with multi-scale structure reconstruction model calculations, the reshaping mechanism is fully understood.

  2. Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis

    NARCIS (Netherlands)

    E.J. Feron (Eric); V.N. Klaren; E.A. Wierenga (Eddy); A. Kijlstra Prof. Dr; G.M.G.M. Verjans (George)

    2001-01-01

    textabstractPURPOSE: The mechanisms involved in reactivations of latent ocular Toxoplasma gondii (Tg) infections in immunocompetent patients are poorly understood. In view of the possible role of T cells in the immunopathogenesis of the disease, ocular infiltrating T cells

  3. Neurocognitive functions in pathological gambling: a comparison with alcohol dependence, Tourette syndrome and normal controls

    NARCIS (Netherlands)

    Goudriaan, Anna E.; Oosterlaan, Jaap; de Beurs, Edwin; van den Brink, Wim

    2006-01-01

    AIMS: Neurocognitive functions in pathological gambling have relevance for the aetiology and treatment of this disorder, yet are poorly understood. This study therefore investigated neurocognitive impairments of executive functions in a group of carefully screened Diagnostic and Statistical Manual

  4. Risk of viral acute gastrointestinal illness from non-disinfected drinking water distribution systems

    Science.gov (United States)

    Acute gastrointestinal illness (AGI) resulting from pathogens directly entering the piping of drinking water distribution systems is insufficiently understood. Here, we estimate AGI incidence attributable to virus intrusions into non-disinfecting municipal distribution systems. Viruses were enumerat...

  5. Fibrinogen function is impaired in whole blood from patients with cyanotic congenital heart disease

    DEFF Research Database (Denmark)

    Jensen, A S; Johansson, Pär I.; Bochsen, Louise

    2013-01-01

    BACKGROUND: Patients with cyanotic congenital heart disease (CCHD) have haemostatic abnormities associated with bleeding and thrombo-embolic events. The haemostatic abnormalities are not fully understood, but recent studies indicate that elevated haematocrit and fibrinogen function may...

  6. 7 CFR 760.812 - Production losses; participant responsibility.

    Science.gov (United States)

    2010-01-01

    ... understood by the county committee; and (5) Providing supporting documentation if the county committee has... otherwise disposed of through commercial channels, production records include: commercial receipts... other than commercial channels, production records for these purposes include: truck scale tickets...

  7. Energy conservation with non-symplectic methods: examples and counter-examples

    OpenAIRE

    Faou, Erwan; Hairer, Ernst; Pham, Truong-Linh

    2004-01-01

    Energy conservation of numerical integrators is well understood for symplectic one-step methods. This article provides new insight into energy conservation with non-symplectic methods. Sufficient conditions and counter-examples are presented.

  8. Distinct in vitro Complement Activation by Various Intravenous Iron Preparations

    NARCIS (Netherlands)

    Hempel, Julia Cordelia; Poppelaars, Felix; da Costa, Mariana Gaya; Franssen, Casper F. M.; de Vlaam, Thomas P G; Daha, Mohamed R.; Berger, Stefan P.; Seelen, Marc A. J.; Gaillard, Carlo A. J. M.

    2017-01-01

    Background: Intravenous (IV) iron preparations are widely used in the treatment of anemia in patients undergoing hemodialysis (HD). All IV iron preparations carry a risk of causing hypersensitivity reactions. However, the pathophysiological mechanism is poorly understood. We hypothesize that a

  9. Accelerated Aging Experiments for Prognostics of Damage Growth in Composite Materials

    Data.gov (United States)

    National Aeronautics and Space Administration — Composite structures are gaining importance for use in the aerospace industry. Compared to metallic structures their behavior is less well understood. This lack of...

  10. Effects of periodic fire on composition and long-term dynamics of Arkansas upland hardwood forests

    Science.gov (United States)

    Martin A. Spetich

    2005-01-01

    Prescribed fire (at historic periodic fire frequencies) is seen as an important but little understood tool in the assortment of management techniques that could help restore oak to Arkansas upland hardwood forests and facilitate the maintenance of these keystone species.

  11. Integrated safety assessment of Indian nuclear power plants for ...

    Indian Academy of Sciences (India)

    1997); that need to be understood and addressed besides the demonstration of safety and economy of Indian. Nuclear Power Plants for extreme external and internal events. Earlier, the progression of two severe accidents at Three Mile ...

  12. A Functional Genomic Analysis of NF1-Associated Learning Disabilities

    National Research Council Canada - National Science Library

    Tang, Shao-Jun

    2008-01-01

    Learning disabilities severely deteriorate the life of many NF1 patients. However, the pathogenic process for NF1-associated learning disabilities has not been fully understood and an effective therapy is not available...

  13. A Functional Genomic Analysis of NF1-Associated Learning Disabilities

    National Research Council Canada - National Science Library

    Tang, Shao-Jun

    2006-01-01

    Learning disabilities severely deteriorate the life of many NFI patients. However, the pathogenic process for NFI-associated learning disabilities has not been fully understood and an effective therapy is not available...

  14. A Functional Genomic Analysis of NF1-Associated Learning Disabilities

    National Research Council Canada - National Science Library

    Tang, Shao-Jun

    2007-01-01

    Learning disabilities severely deteriorate the life of many NF1 patients. However, the pathogenic process for NF1-associated learning disabilities has not been fully understood and an effective therapy is not available...

  15. Working memory accuracy for multiple targets is driven by reward expectation and stimulus contrast with different time-courses

    NARCIS (Netherlands)

    Klink, P. Christiaan; Jeurissen, Danique; Theeuwes, Jan; Denys, Damiaan; Roelfsema, Pieter R.

    2017-01-01

    The richness of sensory input dictates that the brain must prioritize and select information for further processing and storage in working memory. Stimulus salience and reward expectations influence this prioritization but their relative contributions and underlying mechanisms are poorly understood.

  16. Perspective: The social science of sustainable bioenergy production in Southeast Asia

    NARCIS (Netherlands)

    Bush, S.R.

    2008-01-01

    The social sciences have made considerable inroads into exploring the politics of environment, land and resources throughout Southeast Asia, yet the social and political character of bioenergy development remains little understood. Current assumptions that bioenergy provides benefits to rural

  17. LTBP bridge performance primer.

    Science.gov (United States)

    2013-12-01

    "The performance of bridges is critical to the overall performance of the highway transportation system in the United States. However, many critical aspects of bridge performance are not well understood. The reasons for this include the extreme diver...

  18. Genetics Home Reference: hereditary sensory and autonomic neuropathy type IE

    Science.gov (United States)

    ... numbers of affected families have been identified in populations around the world. Related Information What information about ... not well understood, the enzyme may help regulate neuron maturation and specialization (differentiation), the ability of neurons ...

  19. Exploring educators' understanding of developing learners' reading ...

    African Journals Online (AJOL)

    Exploring educators' understanding of developing learners' reading skills and their readiness to implement CAPS. ... Journal for Language Teaching ... Phase English First Additional Language teachers understood about reading and teaching reading, and the strategies they used to develop learners' reading skills.

  20. Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

    NARCIS (Netherlands)

    Hooshmand, B.; Polvikoski, T.; Kivipelto, M.; Tanskanen, M.; Myllykangas, L.; Erkinjuntti, T.; Makela, M.; Oinas, M.; Paetau, A.; Scheltens, P.; van Straaten, E.C.W.; Sulkava, R.; Solomon, A.

    2013-01-01

    Elevated plasma total homocysteine is associated with increased risk of dementia/Alzheimer's disease, but underlying pathophysiological mechanisms are not fully understood. This study investigated possible links between baseline homocysteine, and post-mortem neuropathological and magnetic resonance

  1. Open Source Intelligence - Doctrine's Neglected Child

    National Research Council Canada - National Science Library

    Pham, Tuan

    2003-01-01

    Of the seven intelligence disciplines, OSINT is least appreciated, understood, or employed by staffs and organizations supporting the operational commander despite past successes at the strategic and tactical levels...

  2. UNHCR and responses to statelessness

    Directory of Open Access Journals (Sweden)

    Mark Manly

    2009-04-01

    Full Text Available UNHCR and other actors have stepped up efforts to address statelessness. However, the global impact of statelessness is not yet sufficiently understood and far more needs to be done.

  3. Linear Models

    CERN Document Server

    Searle, Shayle R

    2012-01-01

    This 1971 classic on linear models is once again available--as a Wiley Classics Library Edition. It features material that can be understood by any statistician who understands matrix algebra and basic statistical methods.

  4. In the clouds

    NARCIS (Netherlands)

    Russchenberg, H.; Wassink, J.

    2012-01-01

    Clouds always used to be the least understood element of the weather system, but that is rapidly changing . Computer clouds increasingly correspond with those in the sky, which promises weather forecasts at street level and more accurate climate scenarios.

  5. Display of individuality in avoidance behavior and risk assessment of inbred mice

    NARCIS (Netherlands)

    Hager, T.; Jansen, R.F.; Pieneman, A.W.; Manivannan, S.N.; Golani, I.; van der Sluis, S.; Smit, A.B.; Verhage, M.; Stiedl, O.

    2014-01-01

    Factors determining individuality are still poorly understood. Rodents are excellent model organisms to study individuality, due to a rich behavioral repertoire and the availability of well-characterized isogenic populations. However, most current behavioral assays for rodents have short test

  6. A Framework for Evaluating Common Operating Environments: Piloting, Lessons Learned, and Opportunities

    Science.gov (United States)

    2011-02-01

    defined set of terminology definitions, which include illustra- tive elaborations, architectural descriptions, and commonly understood commercial exam ...Because the technical solution under review used many aspects of service-oriented architectures ( SOAs ), the SEI team leveraged insights gleaned

  7. Trichomonas vaginalis infection and human immunodeficiency virus acquisition in African women

    NARCIS (Netherlands)

    van der Pol, Barbara; Kwok, Cynthia; Pierre-Louis, Bosny; Rinaldi, Anne; Salata, Robert A.; Chen, Pai-Lien; van de Wijgert, Janneke; Mmiro, Francis; Mugerwa, Roy; Chipato, Tsungai; Morrison, Charles S.

    2008-01-01

    Background. Trichomoniasis vaginalis is the most common nonviral sexually transmitted infection (STI) worldwide, with a particularly high prevalence in regions of human immunodeficiency virus (HIV) endemicity. However, its impact as a cofactor for HIV acquisition is poorly understood. Methods.

  8. Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction

    DEFF Research Database (Denmark)

    Frydenlund Michelsen, Charlotte; Khademi, Seyed Mohammad Hossein; Johansen, Helle Krogh

    2016-01-01

    The effect of polymicrobial interactions on pathogen physiology and how it can act either to limit pathogen colonization or to potentiate pathogen expansion and virulence are not well understood. Pseudomonas aeruginosa and Staphylococcus aureus are opportunistic pathogens commonly found together ...

  9. Dynamics of births and juvenile recruitment in Mara-Serengeti ungulates in relation to climatic and land use changes

    NARCIS (Netherlands)

    Ogutu, Joseph O.; Piepho, Hans-Peter; Dublin, Holly T.; Bhola, Nina; Reid, Robin S.

    Natality and recruitment govern animal population dynamics, but their responses to fluctuating resources, competition, predation, shifting habitat conditions, density feedback and diseases are poorly understood. To understand the influences of climatic and land use changes on population dynamics, we

  10. Redistribution of myocardial perfusion during permanent dual chamber pacing in symptomatic non-obstructive hypertrophic cardiomyopathy : A quantitative positron emission tomography study

    NARCIS (Netherlands)

    Posma, JL; Blanksma, PK; vanderWall, EE

    Dual chamber pacing causes significant symptomatic improvement in many patients with hypertrophic cardiomyopathy. The mechanism behind this beneficial response is not fully understood. Positron emission tomography showed a redistribution of myocardial flow during pacing in a patient with

  11. Essential Tensions in Interdisciplinary Scholarship: Navigating Challenges in Affect, Epistemologies, and Structure in Environment-Society Research Centers

    Science.gov (United States)

    Turner, V. Kelly; Benessaiah, Karina; Warren, Scott; Iwaniec, David

    2015-01-01

    Scholars have enumerated unique challenges to collaborative interdisciplinary research, many of which evade prescriptive solutions. Some of these challenges can be understood as "essential tensions," necessary and persistent contradictory imperatives in the scientific process. Drawing from interviews with internationally renowned…

  12. Anticipation Behavior Upstream of a Bottleneck

    NARCIS (Netherlands)

    Duives, D.C.; Daamen, W.; Hoogendoorn, S.P.

    2014-01-01

    Whether pedestrian movements do or do not follow similar patterns as vehicular traffic while experiencing congestion is not entirely understood. Using data gathered during bottleneck experiments under laboratory conditions, the phenomenon of anticipation before entering congestion is studied. This

  13. The importance of multidisciplinary teamwork and team climate for relational coordination among teams delivering care to older patients

    NARCIS (Netherlands)

    J.M. Hartgerink (Jacqueline); J.M. Cramm (Jane); T.J.E.M. Bakker (Ton); A.M. van Eijsden (A.); J.P. Mackenbach (Johan); A.P. Nieboer (Anna)

    2013-01-01

    textabstractAim: To identify predictors of relational coordination among professionals delivering care to older patients. Background: Relational coordination is known to enhance quality of care in hospitals. The underlying mechanisms, however, remain poorly understood. Design: This cross-sectional

  14. Current algebra, baryons and quark confinement

    International Nuclear Information System (INIS)

    Witten, E.

    1983-01-01

    It is shown that ordinary baryons can be understood as solitons in current algebra effective lagrangiangs. The formation of color flux tubes can also be seen in current algebra, under certain conditions. (orig.)

  15. Integrating personality structure, personality process, and personality development

    NARCIS (Netherlands)

    Baumert, Anna; Schmitt, Manfred; Perugini, Marco; Johnson, Wendy; Blum, Gabriela; Borkenau, Peter; Costantini, Giulio; Denissen, J.J.A.; Fleeson, William; Grafton, Ben; Jayawickreme, Eranda; Kurzius, Elena; MacLeod, Colin; Miller, Lynn C.; Read, Stephen J.; Robinson, Michael D.; Wood, Dustin; Wrzus, Cornelia

    2017-01-01

    In this target article, we argue that personality processes, personality structure, and personality development have to be understood and investigated in integrated ways in order to provide comprehensive responses to the key questions of personality psychology. The psychological processes and

  16. Latah : An indonesian startle syndrome

    NARCIS (Netherlands)

    Bakker, Mirte J.; van Dijk, J. Gert; Pramono, Astuti; Sutarni, Sri; Tijssen, Marina A. J.

    The nature of culture-specific startles syndromes such as Latah in Indonesia and Malaysia is ill understood. Hypotheses concerning their origin include sociocultural behavior, psychiatric disorders, and neurological syndromes. The various disorders show striking similarities despite occurring in

  17. Effects of introducing heterologous pathways on microbial metabolism with respect to metabolic optimality

    DEFF Research Database (Denmark)

    Kim, Hyun Uk; Kim, Byoungjin; Seung, Do Young

    2014-01-01

    Although optimality of microbial metabolism under genetic and environmental perturbations is well studied, the effects of introducing heterologous reactions on the overall metabolism are not well understood. This point is important in the field of metabolic engineering because heterologous reacti...

  18. When asset management and organizations meet: accounting for employee experiences

    NARCIS (Netherlands)

    Schraven, Daan; Hartmann, Andreas; Dewulf, Geert P.M.R.

    2015-01-01

    For some time, organisations have encountered challenges when implementing asset management, particularly when closing the gap between how the asset management is understood by employees and how they support it in practice. Maturity models, common applied evaluations for implementing asset

  19. 77 FR 27799 - Proposed Collection; Comment Request

    Science.gov (United States)

    2012-05-11

    ... resources) is minimized, collection instruments are clearly understood, and the impact of collection... the Import Price Indexes include market analysis, inflation forecasting, contract escalation, and... produce monthly and quarterly estimates of inflation-adjusted trade flows. Without continuation of data...

  20. Perinatal exposure to organohalogen pollutants decreases vasopressin content and its mRNA expression in magnocellular neuroendocrine cells activated by osmotic stress in adult rats

    Science.gov (United States)

    Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) are environmental pollutants that produce neurotoxicity and neuroendocrine disruption. They affect the vasopressinergic system but their disruptive mechanisms are not well understood. Our group reported t...

  1. Gastroesophageal pressure gradients in gastroesophageal reflux disease: relations with hiatal hernia, body mass index, and esophageal acid exposure

    NARCIS (Netherlands)

    de Vries, Durk R.; van Herwaarden, Margot A.; Smout, André J. P. M.; Samsom, Melvin

    2008-01-01

    OBJECTIVES: The roles of intragastric pressure (IGP), intraesophageal pressure (IEP), gastroesophageal pressure gradient (GEPG), and body mass index (BMI) in the pathophysiology of gastroesophageal reflux disease (GERD) and hiatal hernia (HH) are only partly understood. METHODS: In total, 149 GERD

  2. Social mapping for communal sensemaking and collaboration: the case of development informatics research in South Africa

    CSIR Research Space (South Africa)

    Van Biljon, J

    2017-05-01

    Full Text Available are well-understood. This work in progress paper proposes social mapping as an innovative way of making sense of the connections between Development Informatics researchers towards understanding the research landscape and behavioural collaboration patterns...

  3. Impact of rainfall pattern on interrill erosion process

    Science.gov (United States)

    The impact of rainfall pattern on the interrill erosion process is not fully understood despite its importance. Systematic rainfall simulation experiments involving different rain intensities, stages, intensity sequences, and surface cover conditions were conducted to investigate the impacts of rain...

  4. Stigmatization in teachers towards adults with attention deficit hyperactivity disorder

    NARCIS (Netherlands)

    Fuermaier, Anselm B.M.; Tucha, Lara; Müller, Kathi; Koerts, Janneke; Hauser, Joachim; Lange, Klaus W; Tucha, Oliver

    2014-01-01

    OBJECTIVES: Attention deficit hyperactivity disorder (ADHD) is understood as a developmental disorder which shares common characteristics between childhood, adolescence and adulthood. However, ADHD is widely associated with misconceptions and misbeliefs which can lead to stigmatization. Teachers

  5. Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Make Rats

    Science.gov (United States)

    Severe thyroid hormone (TH) deficiency during critical phases of brain development results in irreversible neurological and cognitive impairments. The mechanisms accounting for this are likely multifactorial, and are not fully understood. Here we pursue the possibility that one i...

  6. Filoviridae

    Science.gov (United States)

    ... molecule of single-stranded, negative-sense RNA. New viral particles are created by budding from the surface of their hosts’ cells; however, filovirus replication strategies are not completely understood. Filovirus history The ...

  7. Cytokine profiles in pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome

    Science.gov (United States)

    In spite of extensive research, immunologic control mechanisms against Porcine Reproductive and Respiratory Syndrome virus (PRRSv) remain poorly understood. Cytokine responses have been exhaustively studied in nursery pigs and show contradictory results. Since no detailed reports on cytokine respons...

  8. TOXICITY COMPARISON OF BIOSURFACTANTS AND SYNTHETIC SURFACTANTS USED IN OIL SPILL REMEDIATION TO TWO ESTUARINE SPECIES

    Science.gov (United States)

    The relative environmental toxicities of synthetic and biogenic surfactants used in oil spill remediation efforts are not well understood. Acute and chronic toxicities of three synthetic surfactants and three microbially produced surfactants were determined and compared in this s...

  9. Psychosis and autism: magnetic resonance imaging study of brain anatomy.

    LENUS (Irish Health Repository)

    Toal, Fiona

    2009-05-01

    Autism-spectrum disorder is increasingly recognised, with recent studies estimating that 1% of children in South London are affected. However, the biology of comorbid mental health problems in people with autism-spectrum disorder is poorly understood.

  10. The structural neuroanatomy of music emotion recognition: evidence from frontotemporal lobar degeneration

    NARCIS (Netherlands)

    Omar, R.; Henley, S.M.D.; Bartlett, J.W.; Hailstone, J.C.; Gordon, E.; Sauter, D.A.; Frost, C.; Scott, S.K.; Warren, J.D.

    2011-01-01

    Despite growing clinical and neurobiological interest in the brain mechanisms that process emotion in music, these mechanisms remain incompletely understood. Patients with frontotemporal lobar degeneration (FTLD) frequently exhibit clinical syndromes that illustrate the effects of breakdown in

  11. Basin F Subregional Groundwater Model

    National Research Council Canada - National Science Library

    Mazion, Edward

    2001-01-01

    The groundwater flow system at Rocky Mountain Arsenal (RMA) is complex. To evaluate proposed remedial alternatives, interaction of the local groundwater flow system with the present contamination control systems must be understood...

  12. Minireview: glucocorticoids--food intake, abdominal obesity, and wealthy nations in 2004

    NARCIS (Netherlands)

    Dallman, Mary F.; la Fleur, Susanne E.; Pecoraro, Norman C.; Gomez, Francisca; Houshyar, Hani; Akana, Susan F.

    2004-01-01

    Glucocorticoids have a major effect on food intake that is underappreciated, although the effects of glucocorticoids on metabolism and abdominal obesity are quite well understood. Physiologically appropriate concentrations of naturally secreted corticosteroids (cortisol in humans, corticosterone in

  13. A Fundamental Investigation into the Deformation and Failure Behavior of Heterogeneous Materials with the Aims of Developing Design Guidelines

    National Research Council Canada - National Science Library

    Ravi-Chandar, Krishnaswamy

    2000-01-01

    ... at the microscale to the macroscale design of composite structures. This is important since the deformation and failure behavior under multiaxial is not well understood, nor are there suitable design guidelines or material allowables clearly defined...

  14. The GSPC: Newest Franchise in al-Qa'ida's Global Jihad

    National Research Council Canada - National Science Library

    Boudali, Lianne K

    2007-01-01

    ... of support in Europe. The alignment of the GSPC with al Qa ida represents a significant change in the group's strategy, however, its decision to join al Qa ida's global jihad should be understood as an act of desperation...

  15. Towards building the silicon cell : A modular approach

    NARCIS (Netherlands)

    Snoep, Jacky L.; Bruggeman, Frank; Olivier, Brett G.; Westerhoff, Hans V.

    Systems Biology aims to understand quantitatively how properties of biological systems can be understood as functions of the characteristics of, and interactions between their macromolecular components. Whereas, traditional biochemistry focused on isolation and characterization of cellular

  16. Markers of Breast Cancer Risk in Women With Benign Breast Disease

    National Research Council Canada - National Science Library

    Mandelson, Margaret

    2002-01-01

    Although certain risk factors for breast cancer, such as never having giving birth, have been established, the biologic mechanisms by which these factors increase the risk of breast cancer is not well understood...

  17. Serotonin-induced down-regulation of cell surface serotonin transporter

    DEFF Research Database (Denmark)

    Jørgensen, Trine Nygaard; Christensen, Peter Møller; Gether, Ulrik

    2014-01-01

    The serotonin transporter (SERT) terminates serotonergic signaling and enables refilling of synaptic vesicles by mediating reuptake of serotonin (5-HT) released into the synaptic cleft. The molecular and cellular mechanisms controlling SERT activity and surface expression are not fully understood...

  18. The identification of genetic pathways involved in vascular adaptations after physical deconditioning versus exercise training in humans

    NARCIS (Netherlands)

    Lammers, G.; Duijnhoven, N.T. van; Hoenderop, J.G.J.; Horstman, A.M.; Haan, A. de; Janssen, T.W.; Graaf, M.J. de; Pardoel, E.M.; Verwiel, E.T.P.; Thijssen, D.H.J.; Hopman, M.T.E.

    2013-01-01

    Physical inactivity and exercise training result in opposite adaptations of vascular structure. However, the molecular mechanisms behind these adaptations are not completely understood. We used a unique study design to examine both vascular characteristics of the superficial femoral artery (using

  19. Compositional and functional stability of aerobic methane consuming communities in drained and rewetted peat meadows

    NARCIS (Netherlands)

    Krause, Sascha; Niklaus, Pascal A.; Morcillo, Sara Badwan; Meima-Franke, M.; Lüke, Claudia; Reim, Andreas; Bodelier, Paul L.E.

    2015-01-01

    The restoration of peatlands is an important strategy to counteract subsidence and loss of biodiversity. However, responses of important microbial soil processes are poorly understood. We assessed functioning, diversity, and spatial organization of methanotrophic communities in drained and rewetted

  20. Neurocognitive functions in pathological gambling: A comparison with alcohol dependence, Tourette syndrome and normal controls.

    NARCIS (Netherlands)

    Goudriaan, A.E.; Oosterlaan, J.; Beurs, de P.; Brink, van den W.

    2006-01-01

    Aims Neurocognitive functions in pathological gambling have relevance for the aetiology and treatment of this disorder, yet are poorly understood. This study therefore investigated neurocognitive impairments of executive functions in a group of carefully screened Diagnostic and Statistical Manual

  1. 75 FR 5346 - Comment Request for Information Collection for Workforce Investment Act National Emergency Grant...

    Science.gov (United States)

    2010-02-02

    ..., collection instruments are clearly understood, and the impact of collection requirements on respondents can...) Reform Act of 2002 (Pub. L. 107-210), as amended by the Trade and Globalization Adjustment Assistance Act...

  2. The Integrin-blocking Peptide RGDS Inhibits Airway Smooth Muscle Remodeling in a Guinea Pig Model of Allergic Asthma

    NARCIS (Netherlands)

    Dekkers, Bart G. J.; Bos, I. Sophie T.; Gosens, Reinoud; Halayko, Andrew J.; Zaagsma, Johan; Meurs, Herman

    2010-01-01

    Rationale: Airway remodeling, including increased airway smooth muscle (ASM) mass and contractility, contributes to airway hyper-responsiveness in asthma. The mechanisms driving these changes are, however, incompletely understood. Recently, an important role for extracellular matrix proteins in

  3. Displacement pile installation effects in sand

    NARCIS (Netherlands)

    Beijer-Lundberg, A.

    2015-01-01

    Installation effects govern the post-installation behaviour of displacement piles in sand. These effects are currently not completely understood. Suitable experimental techniques to model these installation effects include field, laboratory and experimental models. In the current thesis a

  4. Greenhouse production systems for people

    NARCIS (Netherlands)

    Giacomelli, G.A.; Sase, S.; Cramer, R.; Hoogeboom, J.; McKenzie, A.; Parbst, K.; Sacrascia-Mugnozza, G.; Selina, P.; Sharp, D.A.; Voogt, J.O.; Weel, van P.A.; Mears, D.

    2012-01-01

    Environmentally sound greenhouse production requires that: demand for market products is understood; greenhouse design addresses the climate circum-stances; input resources are available and consumed efficiently, and; there must be a reasonable balance of production products to the environmental

  5. Comparison of kinome profiles of Barrett's esophagus with normal squamous esophagus and normal gastric cardia

    NARCIS (Netherlands)

    van Baal, Jantine W. P. M.; Diks, Sander H.; Wanders, Ronald J. A.; Rygiel, Agnieskza M.; Milano, Francesca; Joore, Jos; Bergman, Jacques J. G. H. M.; Peppelenbosch, Maikel P.; Krishnadath, Kausilia K.

    2006-01-01

    The precursor metaplastic mucosal lesion that predisposes for esophageal adenocarcinoma is Barrett's esophagus. Because the signal transduction events that occur in Barrett's esophagus are poorly understood, this study aimed at generating a comprehensive description of cellular kinase activity in

  6. Progressive Motor Deficit is Mediated by the Denervation of Neuromuscular Junctions and Axonal Degeneration in Transgenic Mice Expressing Mutant (P301S) Tau Protein

    NARCIS (Netherlands)

    Yin, Zhuoran; Valkenburg, Femke; Hornix, Betty E; Mantingh-Otter, Ietje; Zhou, Xingdong; Mari, Muriel; Reggiori, Fulvio; Van Dam, Debby; Eggen, Bart J L; De Deyn, Peter P; Boddeke, Erik

    2017-01-01

    Tauopathies include a variety of neurodegenerative diseases associated with the pathological aggregation of hyperphosphorylated tau, resulting in progressive cognitive decline and motor impairment. The underlying mechanism for motor deficits related to tauopathy is not yet fully understood. Here, we

  7. Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b

    NARCIS (Netherlands)

    Lüdtke, Timo H.-W.; Farin, Henner F.; Rudat, Carsten; Schuster-Gossler, Karin; Petry, Marianne; Barnett, Phil; Christoffels, Vincent M.; Kispert, Andreas

    2013-01-01

    Vertebrate organ development relies on the precise spatiotemporal orchestration of proliferation rates and differentiation patterns in adjacent tissue compartments. The underlying integration of patterning and cell cycle control during organogenesis is insufficiently understood. Here, we have

  8. Non-Linear Finite Element Analysis of Viscoelastic Materials

    National Research Council Canada - National Science Library

    Negaard, Gordon

    1998-01-01

    .... It would be useful if viscoelastic materials could be used to damp the vibration of such structures, however the behavior of a viscoelastic material in an extremely high g-loading is not well understood...

  9. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

    NARCIS (Netherlands)

    Reid, Glen; Wielinga, Peter; Zelcer, Noam; van der Heijden, Ingrid; Kuil, Annemieke; de Haas, Marcel; Wijnholds, Jan; Borst, Piet

    2003-01-01

    Prostaglandins are involved in a wide variety of physiological and pathophysiological processes, but the mechanism of prostaglandin release from cells is not completely understood. Although poorly membrane permeable, prostaglandins are believed to exit cells by passive diffusion. We have

  10. MBO works for managers who understand, apply system.

    Science.gov (United States)

    McConkey, D D

    1979-09-01

    Where MBO has suceeded, managers thoroughly understood, planned, and adapted the system to their organization's needs. Informed managers in nonprofit organizations can avoid the common mistakes made in business and industry in the 25 years since MBO was first adopted.

  11. Feelings of loneliness, but not social isolation, predict dementia onset: Results from the Amsterdam Study of the Elderly (AMSTEL)

    NARCIS (Netherlands)

    Holwerda, T.J.; Deeg, D.; Beekman, A.T.F.; van Tilburg, T.G.; Stek, M.L.; Jonker, C.; Schoevers, R.A.

    2014-01-01

    Background Known risk factors for Alzheimer's disease and other dementias include medical conditions, genetic vulnerability, depression, demographic factors and mild cognitive impairment. The role of feelings of loneliness and social isolation in dementia is less well understood, and prospective

  12. Feelings of loneliness, but not social isolation, predict dementia onset : results from the Amsterdam Study of the Elderly (AMSTEL)

    NARCIS (Netherlands)

    Holwerda, Tjalling Jan; Deeg, Dorly J. H.; Beekman, Aartjan T. F.; van Tilburg, Theo G.; Stek, Max L.; Jonker, Cees; Schoevers, Robert A.

    Background Known risk factors for Alzheimer's disease and other dementias include medical conditions, genetic vulnerability, depression, demographic factors and mild cognitive impairment. The role of feelings of loneliness and social isolation in dementia is less well understood, and prospective

  13. A Simple Illustration for the Need of Multiple Comparison Procedures

    Science.gov (United States)

    Carter, Rickey E.

    2010-01-01

    Statistical adjustments to accommodate multiple comparisons are routinely covered in introductory statistical courses. The fundamental rationale for such adjustments, however, may not be readily understood. This article presents a simple illustration to help remedy this.

  14. Metaphysical Experience and Constitutive Error in Adorno's "Meditations on Metaphysics"

    NARCIS (Netherlands)

    Skirke, C.

    2012-01-01

    That current ideals of cognition impoverish experience is a classical observation, and complaint, of the early Frankfurt School. Adorno reacts to this phenomenon in several ways, among them his conception of metaphysical experiences. Metaphysical experiences are conventionally understood as

  15. Arabian Sea oceanography and fisheries

    Digital Repository Service at National Institute of Oceanography (India)

    Madhupratap, M.; Nair, K.N.V.; Venugopal, P.; Gauns, M.; Haridas, P.; Gopalakrishnan, T.C.; Nair, K.K.C.

    The physical and chemical forcing which drive the Arabian production is now fairly well understood. The main attributes, which contribute to the productivity are (1) the boundary processes which manifest as upwelling during summer monsoon and (2...

  16. High-performance work systems and creativity implementation : the role of psychological capital and psychological safety

    NARCIS (Netherlands)

    Agarwal, Promila; Farndale, E.

    Unimplemented creative ideas are potentially wasted opportunities for organisations. Although it is largely understood how to encourage creativity among employees, how to ensure this creativity is implemented remains underexplored. The objective of the current study is to identify the underlying

  17. A history of the pedagogy of voluntary attention

    DEFF Research Database (Denmark)

    Ljungdalh, Anders Kruse

    2016-01-01

    The article explores the pedagogical recommendations within late nineteenth century psychological literature on voluntary attention, focusing on what was then understood as pathological conditions of attention. The purpose of the article is double. First, to investigate the reasoning embedded in ...

  18. Elevated Plasma Corticosterone Decreases Yolk Testosterone and Progesterone in Chickens : Linking Maternal Stress and Hormone-Mediated Maternal Effects

    NARCIS (Netherlands)

    Henriksen, Rie; Groothuis, Ton G.; Rettenbacher, Sophie; Bartell, Paul A.

    2011-01-01

    Despite considerable research on hormone-mediated maternal effects in birds, the underlying physiology remains poorly understood. This study investigated a potential regulation mechanism for differential accumulation of gonadal hormones in bird eggs. Across vertebrates, glucocorticoids can suppress

  19. Nasal allergen deposition leads to conjunctival mast cell degranulation in allergic rhinoconjunctivitis

    NARCIS (Netherlands)

    Callebaut, Ina; de Vries, Annick; Steelant, Brecht; Hox, Valérie; Bobic, Sonja; van Gerven, Laura; Ceuppens, Jan L.; Hellings, Peter W.

    2014-01-01

    Background: The naso-ocular interaction in allergic rhinoconjunctivitis is well recognized from epidemiological, clinical, and experimental observations. The precise mechanisms remain incompletely understood. A new mouse model of allergic rhinoconjunctivitis was used to investigate the contribution

  20. Predictive Models of Nanotoxicity: Relationship of Physicochemical Properties to Particle Movement Through Biological Barriers

    Science.gov (United States)

    Understanding the linkage between the physicochemical (PC) properties of nanoparticles (NP) and their activation of biological systems is poorly understood, yet fundamental to predicting nanotoxicity, idenitifying mode of actions and developing appropriate and effective regul...

  1. Litter decomposition and nutrient dynamics of ten selected tree ...

    African Journals Online (AJOL)

    Litter decomposition processes in tropical rainforests are still poorly understood. Leaf litter decomposition and nutrient dynamics of ten contrasting tree species, Entandraphragma utile, Guibourtia tessmannii, Klainedoxa gabonensis, Musanga cecropioides, Panda oleosa, Plagiostyles africana, Pterocarpus soyauxii, ...

  2. The association of genotype-based inbreeding coefficient with a range of physical and psychological human traits

    NARCIS (Netherlands)

    Verweij, K.J.H.; Abdellaoui, A.; Veijola, J.; Sebert, S.; Koiranen, M.; Keller, M.C.; Jarvelin, M.R.; Zietsch, B.P.

    2014-01-01

    Across animal species, offspring of closely related mates exhibit lower fitness, a phenomenon called inbreeding depression. Inbreeding depression in humans is less well understood because mating between close relatives is generally rare and stigmatised, confounding investigation of its effect on

  3. The Association of Genotype-Based Inbreeding Coefficient with a Range of Physical and Psychological Human Traits

    NARCIS (Netherlands)

    Verweij, K.J.H.; Abdellaoui, A.; Veijola, J.; Sebert, S.; Koiranen, M.; Keller, M.C.; Järvelin, M.R.; Zietsch, B.P.

    2014-01-01

    Across animal species, offspring of closely related mates exhibit lower fitness, a phenomenon called inbreeding depression. Inbreeding depression in humans is less well understood because mating between close relatives is generally rare and stigmatised, confounding investigation of its effect on

  4. Greenhouse gas inventory, fiscal year 2011 : Michigan Department of Transportation.

    Science.gov (United States)

    2013-11-01

    The risk of climate change to governmental operations is not yet fully understood; : however, it is changing the way organizations think about the impact of their operations : on the environment. How MDOT addresses this issue is driven by a combinati...

  5. Cerebral Cavernous Malformation and Hemorrhage

    Science.gov (United States)

    ... Text Size: SMALL • LARGE Cerebral Cavernous Angioma and Hemorrhage By Jack Hoch; Reviewed by Dr. Issam Awad ... for years, the mechanism by which these lesions hemorrhage remains poorly understood. Hemorrhage Types Since cavernous angiomas ...

  6. Mechanisms of Very Late Drug-Eluting Stent Thrombosis Assessed by Optical Coherence Tomography

    DEFF Research Database (Denmark)

    Taniwaki, Masanori; Radu, Maria D; Zaugg, Serge

    2016-01-01

    BACKGROUND: The pathomechanisms underlying very late stent thrombosis (VLST) after implantation of drug-eluting stents (DES) are incompletely understood. Using optical coherence tomography, we investigated potential causes of this adverse event. METHODS AND RESULTS: Between August 2010 and Decemb...

  7. Chronic Pseudomonas aeruginosa biofilm infection impairs murine S100A8/A9 and neutrophil effector cytokines—implications for delayed wound closure?

    DEFF Research Database (Denmark)

    Trøstrup, Hannah; Lerche, Christian Johann; Christophersen, Lars Jackie

    2017-01-01

    The impact of Pseudomonas aeruginosa biofilm infections in chronic wounds and clinical implication for healing is receiving increased attention. However, the pathophysiology of host/pathogen interplay is not fully understood. By further revealing the mechanisms, necessary new treatment strategies...

  8. Titanium dioxide nanoparticles cause genotoxicity in human lung epithelial cells

    Science.gov (United States)

    The use of engineered nanoparticles in consumer products is steadily increasing. However, the health effects of exposure to these nanoparticles are not thoroughly understood. This study investigated the genotoxicity of six titanium dioxide and two cerium oxide nanoparticles of va...

  9. The genotoxicity of titanium dioxide and cerium oxide nanoparticles in vitro

    Science.gov (United States)

    The use ofengineered nanoparticles in both current and future consumer products is steadily increasing. However, the health effects of exposure to these nanoparticles are not thoroughly understood. Recently, particular emphasis has been placed on particle characterization and the...

  10. The challenges of testing metal and metal oxide nanoparticles in algal bioassays: titanium dioxide and gold nanoparticles as case studies

    DEFF Research Database (Denmark)

    Hartmann, Nanna Isabella Bloch; Engelbrekt, Christian; Zhang, Jingdong

    2013-01-01

    Aquatic toxicology of engineered nanoparticles is challenged by methodological difficulties stemming partly from highly dynamic and poorly understood behavior of nanoparticles in biological test systems. In this paper scientific and technical challenges of testing not readily soluble nanoparticle...

  11. The arcuate fasciculus network and verbal deficits in psychosis

    NARCIS (Netherlands)

    Kenney, Joanne P.M.; McPhilemy, Genevieve; Scanlon, Cathy; Najt, Pablo; McInerney, Shane; Arndt, Sophia; Scherz, Elisabeth; Byrne, Fintan; Leemans, Alexander; Jeurissen, Ben; Hallahan, Brian; McDonald, Colm; Cannon, Dara M.

    2017-01-01

    Verbal learning (VL) and fluency (VF) are prominent cognitive deficits in psychosis, of which the precise neuroanatomical contributions are not fully understood. We investigated the arcuate fasciculus (AF) and its associated cortical regions to identify structural abnormalities contributing to these

  12. Environmental Exposures Are Important Risk Factors for Infection Toxoplasma gondii and Helicobacter pylori

    Science.gov (United States)

    Background: An estimated 70% of Americans suffer chronic infections. Helicobacter pylori and Toxoplasma gondii affect an estimated 35% and 15% of Americans, respectively. Despite their heavy burden, environmental transmission of these infections is not well understood. Object...

  13. 9 CFR 317.313 - Nutrient content claims; general principles.

    Science.gov (United States)

    2010-01-01

    ... three 40 gram portions of food, or combinations of foods, from two or more of the following four food... form commonly understood to be, a breakfast, lunch, dinner, meal, or entre. Such representations may be...

  14. 9 CFR 381.413 - Nutrient content claims; general principles.

    Science.gov (United States)

    2010-01-01

    ... three 40 gram portions of food, or combinations of foods, from two or more of the following four food... form commonly understood to be, a breakfast, lunch, dinner, meal, or entrèe. Such representations may...

  15. Modelled long term trends of surface ozone over South Africa

    CSIR Research Space (South Africa)

    Naidoo, M

    2011-09-01

    Full Text Available Currently little is understood about the potential local response of air quality to anthropogenically induced changes in the regional climate of southern Africa. Such changes are likely to influence the future transport and chemistry of air...

  16. Neuroticism and extraversion are associated with amygdala resting-state functional connectivity

    NARCIS (Netherlands)

    Aghajani, Moji; Veer, Ilya M.; van Tol, Marie-Jose; Aleman, André; van Buchem, Mark A.; Veltman, Dick J.; Rombouts, Serge A. R. B.; van der Wee, Nic J.

    The personality traits neuroticism and extraversion are differentially related to socioemotional functioning and susceptibility to affective disorders. However, the neurobiology underlying this differential relationship is still poorly understood. This discrepancy could perhaps best be studied by

  17. Microphytobenthos and benthic macroalgae determine sediment organic matter composition in shallow photic sediments

    NARCIS (Netherlands)

    Hardison, A.K.; Canuel, E.A/; Anderson, I.C.; Tobias, C.R.; Veuger, B.; Waters, M.N.

    2013-01-01

    Microphytobenthos and benthic macroalgae play an important role in system metabolism within shallow coastal bays. However, their independent and interactive influences on sediment organic matter (SOM) are not well understood. We investigated the influence of macroalgae and microphytobenthos on SOM

  18. Probing the genome-scale metabolic landscape of Bordetella pertussis, the causative agent of whooping cough

    NARCIS (Netherlands)

    dos Santos, Filipe Branco; Olivier, Brett G.; Boele, Joost; Krumpochova, Petra; Klau, Gunnar W.; Giera, Martin; Teusink, Bas

    2017-01-01

    Whooping cough is a highly contagious respiratory disease caused by Bordetella pertussis. Despite widespread vaccination, its incidence has been rising alarmingly, and yet, the physiology of B. pertussis remains poorly understood. We combined genome-scale metabolic reconstruction, a novel

  19. Conquering the Downwind Turn - SFTE Paper Followup

    National Research Council Canada - National Science Library

    Kolwey, Herman

    2000-01-01

    ...". That's 64 accidents per year to this problem, one piece of which is the turning downwind problem. It also States that: "The way human beings perceive their own movement is fairly well understood". I'm not so sure.

  20. Markers of Breast Cancer Risk in Women With Benign Breast Disease

    National Research Council Canada - National Science Library

    Mandelson, Margaret

    2001-01-01

    Although certain risk factors for breast cancer, such as never having giving birth, have been established, the biologic mechanisms by which these factors increase the risk of breast cancer is not well understood...

  1. Conspiracy Rhetoric: From Pragmatism to Fantasy in Public Discourse.

    Science.gov (United States)

    Goodnight, G. Thomas; Poulakos, John

    1981-01-01

    Notes that conspiracy charges have come to characterize mainstream political drama. Analyzes dimensions of the Watergate scandal so that the manner in which conspiracy rhetoric unfolds in political drama may be better understood. (PD)

  2. Population-level consequences of complementary sex determination in a solitary parasitoid

    NARCIS (Netherlands)

    de Boer, JG; Groenen, Martien Am; Pannebakker, Bart A; Beukeboom, Leo W; Kraus, Robert H S

    2015-01-01

    BACKGROUND: Sex determination mechanisms are known to be evolutionarily labile but the factors driving transitions in sex determination mechanisms are poorly understood. All insects of the Hymenoptera are haplodiploid, with males normally developing from unfertilized haploid eggs. Under

  3. A Cellular Game of Telephone: Trans Tissue Reprogramming of Responses to Toxic Stimuli

    Science.gov (United States)

    Exposure to air pollution is a leading cause of cardiopulmonary morbidity and mortality; however, while these effects outside the lung have been associated with aberrant oxidative stress and inflammation, the underlying molecular mechanisms are poorly understood. We hypothesized ...

  4. Disentangling the relation between young immigrants' host country identification and their friendships with natives

    NARCIS (Netherlands)

    Leszczensky, Lars; Stark, Tobias H.; Flache, Andreas; Munniksma, Anke

    2016-01-01

    Immigrants who strongly identify with the host country have more native friends than immigrants with weaker host country identification. However, the mechanisms underlying this correlation are not well understood. Immigrants with strong host country identification might have stronger preferences for

  5. Environmental changes during secondary succession in a tropical dry forest in Mexico

    NARCIS (Netherlands)

    Lebrija Trejos, E.E.; Pérez-Garcia, E.A.; Meave, J.; Poorter, L.; Bongers, F.

    2011-01-01

    Vegetation and environment change mutually during secondary succession, yet the idiosyncrasies of the vegetation effect on the understorey environment are poorly understood. To test whether the successional understorey environment changes predictably and is shaped by the structure and seasonality of

  6. How should the completeness and quality of curated nanomaterial data be evaluated?

    NARCIS (Netherlands)

    Marchese Robinson, Richard L.; Lynch, Iseult; Peijnenburg, Willie; Rumble, John; Klaessig, Frederick; Marquardt, Clarissa; Rauscher, Hubert; Puzyn, Tomasz; Purian, Ronit; Åberg, Christoffer; Karcher, Sandra; Vriens, Hanne; Hoet, Peter; Hoover, Mark; Hendren, Christine; Harper, Stacey

    2016-01-01

    Nanotechnology is of increasing significance. Curation of nanomaterial data into electronic databases offers opportunities to better understand and predict nanomaterials’ behaviour. This supports innovation in, and regulation of, nanotechnology. It is commonly understood that curated data need to be

  7. Quantifying the annual fish harvest from South Africa's largest ...

    African Journals Online (AJOL)

    -shore communities is poorly understood. This study is the first comprehensive assessment of recreational and subsistence angling undertaken in an inland fishery in South Africa. The study was conducted on the 360 km2 Lake Gariep, South ...

  8. Origins and fundamentals of nodal aberration theory

    Science.gov (United States)

    Rogers, John R.

    2017-11-01

    Nodal Aberration Theory, developed by Kevin Thompson and Roland Shack, predicts several important aberration phenomena but remains poorly understood. To de-mystify the theory, we describe the origins and fundamental concepts of the theory.

  9. What drives the increased phytoplankton biomass in the Arabian Sea?

    Digital Repository Service at National Institute of Oceanography (India)

    PrasannaKumar, S.; Roshin, R.P.; Narvekar, J.; DineshKumar, P.K.; Vivekanandan, E.

    The seasonal variability of phytoplankton biomass in the Arabian Sea, though a well researched topic, its inter-annual variability is less explored and understood. Analysis of the satellite-derived chlorophyll pigment concentration in the Arabian...

  10. Aging road user, bicyclist, and pedestrian safety : effective bicycling signs and preventing left-turn crashes.

    Science.gov (United States)

    2013-09-01

    Task 1 of this report drivers' knowledge of various bicycle warning signs and pavement markings were assessed. In general knowledge was high. Share the Road and Three Foot Minimum signs were generally more quickly understood and recognized in version...

  11. Statistical Compilation of the ICT Sector and Policy Analysis | Page 2 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ICTs) continues to widen and deepen, so too does its impact on economic development. However, much work needs to be done before the linkages between economic development and ICTs can be understood in a systematic and meaningful ...

  12. Genetic variation in the inwardly rectifying K channel subunits KCNJ3 (GIRK1) and KCNJ5 (GIRK4) in patients with sinus node dysfunction

    DEFF Research Database (Denmark)

    Holmegard, Haya N; Theilade, Juliane; Benn, Marianne

    2010-01-01

    BACKGROUND: Sinus node dysfunction (SND) is a heterogeneous disorder of unknown etiology characterized by a variety of supraventricular arrhythmias with symptoms of syncope, palpitations, and dizziness. The mechanism underlying the abnormal rhythm is incompletely understood. OBJECTIVE: Because va...

  13. Targeting the Plains of Venus from Orbit

    Science.gov (United States)

    Sharpton, V. L.

    2014-05-01

    Lowland plains house a spectacular array of poorly understood volcanic, tectonic, and impact features that are key to settling the continuing global stratigraphy debate and resolving how the only other accessible Earth-sized planet has evolved.

  14. Physical activity in the school setting: cognitive performance is not affected by three different types of acute exercise

    NARCIS (Netherlands)

    Van den Berg, Vera; Saliasi, Emi; De Groot, Renate; Jolles, Jelle; Chinapaw, Mai; Singh, Amika

    2016-01-01

    Recent studies indicate that a single bout of physical exercise can have immediatepositive effects on cognitive performance of children and adolescents. However, thetype of exercise that affects cognitive performance the most in young adolescents isnot fully understood. Therefore, this controlled

  15. The association between leisure time physical activity and smoking in adolescence: an examination of potential mediating and moderating factors

    NARCIS (Netherlands)

    Verkooijen, K.T.; Nielsen, G.A.; Kremers, S.P.J.

    2008-01-01

    Although physical activity has been associated negatively with smoking in adolescence, the association is not well understood. Purpose: This study examines the relationship between adolescents' leisure time physical activity and smoking behavior, while considering BMI, weight concern, sense of

  16. 35 years of electron scattering

    International Nuclear Information System (INIS)

    Walecka, J.D.

    1986-01-01

    Historical aspects of electron reaction physics are presented. The presently understood picture of nuclear structure and the electron-nucleus interactions are discussed within the framework of the standard model

  17. Police message diffusion on Twitter : analysing the reach of social media communications

    NARCIS (Netherlands)

    van de Velde, Bob; Meijer, Albert; Homburg, Vincent

    2015-01-01

    Social media are becoming increasingly important for communication between government organisations and citizens. Although research on this issue is expanding, the structure of these new communication patterns is still poorly understood. This study contributes to our understanding of these new

  18. An Architecture for Sustainability Assessment: the Case of Nuclear Energy in Belgium

    International Nuclear Information System (INIS)

    Laes, Erik; Meskens, Gaston

    2003-01-01

    In this paper, we have defended a more argumentative or deliberative approach to questions involving guiding ideas for society such as sustainability. However, this approach should be carefully considered and planned in view of the quality criteria developed in this paper. In particular, tensions between conflicting demands made by different criteria are likely to emerge during the course of a participatory exercise: Tension between 'integration' (understood as consensus) and 'fairness' (understood as the ability to challenge claims); Tension between 'fairness' (understood as a power-free, creative dialogue) and argumentative depth of the debate; Tension between 'competence' (understood as the need for an active involvement by the research team) and 'participation'. Deliberative approaches, however essential they might be for contributing to a more 'sustainable' solution, are not without problems of their own

  19. 78 FR 40020 - Fenbuconazole; Pesticide Tolerances

    Science.gov (United States)

    2013-07-03

    ... applied to the animal data for the quantification of human risk (Q1*). This classification was based on a... altered DNA methylation. It is not clearly understood whether these biochemical events are directly...

  20. 76 FR 15012 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Science.gov (United States)

    2011-03-18

    ... Representative (Series 7) United Kingdom Securities Representative (Series 17) or Canada Securities..., IRI, Modern Woodmen, Navidar, NSCP, PSD, Quasar, UPFS, Scottrade, SIFMA, Sutherland, TIAA, Wellington... other persons'' are not legal terms of art but, rather, comport with commercially understood operating...

  1. Surface-groundwater interactions in hard rocks in Sardon Catchment of western Spain: an integrated modeling approach

    NARCIS (Netherlands)

    Tanvir Hassan, S.M.; Lubczynski, M.; Niswonger, R.G.; Su, Zhongbo

    2014-01-01

    The structural and hydrological complexity of hard rock systems (HRSs) affects dynamics of surface–groundwater interactions. These complexities are not well described or understood by hydrogeologists because simplified analyses typically are used to study HRSs. A transient, integrated hydrologic

  2. Serum vaccine antibody concentrations in children exposed to perfluorinated compounds

    DEFF Research Database (Denmark)

    Grandjean, Philippe; Andersen, Elisabeth Wreford; Budtz-Jørgensen, Esben

    2012-01-01

    Perfluorinated compounds (PFCs) have emerged as important food contaminants. They cause immune suppression in a rodent model at serum concentrations similar to those occurring in the US population, but adverse health effects of PFC exposure are poorly understood....

  3. The Impact of Organizational Culture on KC-135 Combat Education and Training

    National Research Council Canada - National Science Library

    Rizer, Scott W

    2002-01-01

    While many of the challenges associated with the combat employment of the KC-135 are well documented and understood, Air Mobility Command's education and training response, a KC-135 Weapons Instructor...

  4. Consequences of meconium stained amniotic fluid: What does the evidence tell us?

    NARCIS (Netherlands)

    Hutton, E.K.; Thorpe, J.

    2014-01-01

    Background: Meconium stained amniotic fluid (MSAF) is common and associated with meconium aspiration syndrome (MAS). Other consequences of meconium passage before birth are less well understood. Methods: We reviewed the literature for original papers reporting on outcomes associated with MSAF.

  5. Latah: an Indonesian startle syndrome

    NARCIS (Netherlands)

    Bakker, Mirte J.; van Dijk, J. Gert; Pramono, Astuti; Sutarni, Sri; Tijssen, Marina A. J.

    2013-01-01

    The nature of culture-specific startles syndromes such as "Latah" in Indonesia and Malaysia is ill understood. Hypotheses concerning their origin include sociocultural behavior, psychiatric disorders, and neurological syndromes. The various disorders show striking similarities despite occurring in

  6. Disease: H01829 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ervous system disease; Epilepsy ... Influenza virus Human herpesvirus 6 ... Autoantibody against NR2B (serum and ...understood. It is currently suspected to represent an inflammatory disorder of the central nervous system. N

  7. Superconductivity: Heike's heritage

    NARCIS (Netherlands)

    van der Marel, D.; Golden, M.

    2011-01-01

    A century ago, Heike Kamerlingh Onnes discovered superconductivity. And yet, despite the conventional superconductors being understood, the list of unconventional superconductors is growing — for which unconventional theories may be required.

  8. Product Line Acquisition in a DoD Organization -- Guidance for Decision Makers

    National Research Council Canada - National Science Library

    Bergey, John; Cohen, Sholom

    2006-01-01

    In the Department of Defense (DoD) acquisition environment, many organizations have not seriously considered adopting a product line approach or are reluctant to because it is not a well-understood acquisition paradigm...

  9. Temperature, age of mating and starvation determine the role of maternal effects on sex allocation in the mealybug Planococcus citri

    NARCIS (Netherlands)

    Ross, Laura; Dealey, Elizabeth J.; Beukeboom, Leo W.; Shuker, David M.

    Environmental effects on sex allocation are common, yet the evolutionary significance of these effects remains poorly understood. Environmental effects might influence parents, such that their condition directly influences sex allocation by altering the relative benefits of producing sons versus

  10. Mercury and methylmercury stream concentrations in a Coastal Plain watershed: A multi-scale simulation analysis

    Science.gov (United States)

    Mercury is a ubiquitous global environmental toxicant responsible for most US fish advisories. Processes governing mercury concentrations in rivers and streams are not well understood, particularly at multiple spatial scales. We investigate how insights gained from reach-scale me...

  11. Advanced Manufacturing Technologies and Strategically Flexible Production. A Review and Outlook

    DEFF Research Database (Denmark)

    Boer, Harry

    2016-01-01

    to require new rationales to organize and manage production systems. However, the compatibility and coherence between changing organizational paradigms and CIM approaches were not extensively explored nor understood. This paper aims to investigate the interactions between the implementation and integration...

  12. Intergenerational environmental effects: Functional signals in offspring transcriptomes and metabolomes after parental jasmonic acid treatment in apomictic dandelion

    NARCIS (Netherlands)

    Verhoeven, K.J.F.; Verbon, Eline H.; Van Gurp, T.P.; Oplaat, C.; Ferreira de Carvalho, J.L.; Morse, Alison M.; Stahl, Mark; Macel, M.; McIntyre, L.M.

    2018-01-01

    Parental environments can influence offspring traits. However, the magnitude of the impact of parental environments on offspring molecular phenotypes is poorly understood. Here, we test the direct effects and intergenerational effects of jasmonic acid (JA) treatment, which is involved in

  13. SENESCENCE-ASSOCIATED DECLINE IN HEPATIC PEROXISOMAL ENZYME ACTIVITIES CORRESPONDS WITH DIMINISHED LEVELS OF RETINOID X RECEPTOR ALPHA, BUT NOT PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA1

    Science.gov (United States)

    AbstractAging is associated with alterations in hepatic peroxisomal metabolism and susceptibility to hepatocarcinogenecity produced by agonists of peroxisome proliferator-activated receptor alpha (PPARa). Mechanisms involved in these effects are not well understood. Howev...

  14. Development of test systems for characterizing emissions from spray polyurethane foam insulation (SPFI)

    Science.gov (United States)

    The relationship between onsite manufacture of spray polyurethane foam insulation (SPFI) and potential exposures to diisocyanates, amines, flame retardants (FRs), blowing agents, aldehydes and other organic compounds that may be emitted from SPFI is not well understood. EPA is de...

  15. Pollinator guilds respond differently to urban habitat fragmentation in a oak-savannah ecosystem

    Science.gov (United States)

    Habitat fragmentation is widely thought to threaten biodiversity. However, response of pollinators to habitat fragmentation is still poorly understood, as pollinator communities are notoriously spatially variable. We investigated pollinator community structure in a highly fragmented oak-savannah ec...

  16. Assessing Organizational Performance

    International Development Research Centre (IDRC) Digital Library (Canada)

    Carroll Salomon

    He is recognized for his expertise in the areas of organisational theory, development, assessment ... Background. Several years ago the International Development Research Centre (IDRC) and Universalia Management ... understood as its structure, governance, leadership, strategic plans and niche management. Human.

  17. Groves and the scientists: Compartmentalization and the building of the bomb

    International Nuclear Information System (INIS)

    Goldberg, S.

    1995-01-01

    The general understood that although the contributions of the scientists were crucial, their work was only one of a host of critical components that made up the totality of the Manhattan Project. copyright 1995 American Institute of Physics

  18. Variation in plant-mediated interactions between rhizobacteria and caterpillars: potential role of soil composition

    NARCIS (Netherlands)

    Pangesti, N.P.D.; Pineda Gomez, A.M.; Dicke, M.; Loon, van J.J.A.

    2015-01-01

    Selected strains of non-pathogenic rhizobacteria can trigger induced systemic resistance (ISR) in plants against aboveground insect herbivores. However, the underlying mechanisms of plant-mediated interactions between rhizobacteria and herbivorous insects are still poorly understood. Using

  19. Probiotics enhance pancreatic glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis

    NARCIS (Netherlands)

    Lutgendorff, Femke; Trulsson, Lena M.; van Minnen, L. Paul; Rijkers, Ger T.; Timmerman, Harro M.; Franzen, Lennart E.; Gooszen, Hein G.; Akkermans, Louis M. A.; Soderholm, Johan D.; Sandstrom, Per A.

    2008-01-01

    Factors determining severity of acute pancreatitis (AP) are poorly understood. Oxidative stress causes acinar cell injury and contributes to the severity, whereas prophylactic probiotics ameliorate experimental pancreatitis. Our objective was to study how probiotics affect oxidative stress,

  20. Urban realities for displaced young women and girls

    Directory of Open Access Journals (Sweden)

    Dan Tyler

    2014-05-01

    Full Text Available Growing numbers of IDPs live in informal settlements in major Afghan urban centres but the ways in which displaced young women and girls are vulnerable in such settings are not well enough understood or addressed.

  1. Do private sustainability standards contribute to income growth and poverty alleviation? A comparison of different coffee certification schemes in Ethiopia

    NARCIS (Netherlands)

    Mitiku, Fikadu; Mey, de Yann; Nyssen, Jan; Maertens, Miet

    2017-01-01

    Private sustainability standards are increasingly important in food trade with developing countries, but the implications for smallholder farmers are still poorly understood. We analyze the implications of different coffee certification schemes in Ethiopia using cross-sectional survey data, and

  2. Sleep deprivation leads to a loss of functional connectivity in frontal brain regions

    NARCIS (Netherlands)

    Verweij, I.M.; Romeijn, N.; Smit, D.J.A.; Piantoni, G.; van Someren, E.J.W.; van der Werf, Y.D.

    2014-01-01

    Background: The restorative effect of sleep on waking brain activity remains poorly understood. Previous studies have compared overall neural network characteristics after normal sleep and sleep deprivation. To study whether sleep and sleep deprivation might differentially affect subsequent

  3. Sleep deprivation leads to a loss of functional connectivity in frontal brain regions

    NARCIS (Netherlands)

    Verweij, Ilse M; Romeijn, Nico; Smit, Dirk Ja; Piantoni, Giovanni; Van Someren, Eus Jw; van der Werf, Ysbrand D

    2014-01-01

    BACKGROUND: The restorative effect of sleep on waking brain activity remains poorly understood. Previous studies have compared overall neural network characteristics after normal sleep and sleep deprivation. To study whether sleep and sleep deprivation might differentially affect subsequent

  4. Neuroependymal Denudation is in Progress in Full-term Human Foetal Spina Bifida Aperta

    NARCIS (Netherlands)

    Sival, Deborah A.; Guerra, Montserrat; den Dunnen, Wilfred F. A.; Batiz, Luis F.; Alvial, Genaro; Castaneyra-Perdomo, Agustin; Rodriguez, Esteban M.

    In human spina bifida aperta (SBA), cerebral pathogenesis [hydrocephalus, Sylvius aqueduct (SA) stenosis and heterotopias] is poorly understood. In animal models, loss of ventricular lining (ependymal denudation) causes SA stenosis and hydrocephalus. We aimed to investigate whether ependymal

  5. Adaptation of neuronal signaling and cell stress response pathways in a multigenic response of Drosophila melanogaster to DDT selection

    Science.gov (United States)

    The adaptation of insect populations to insecticidal control is a continual threat human health and sustainable agriculture practices, but many complex genomic mechanisms involved remain poorly understood. A systems approach was applied to investigate the interconnections between structural and func...

  6. Geometric analysis of an observer on a spherical earth and an aircraft or satellite

    Science.gov (United States)

    2013-09-30

    This memorandum contains a large amount of technical detail. However, in significant contrast, : it addresses an easily-understood and fundamental need in surveillance and navigation systems : analysis quantifying the geometry of two locations re...

  7. ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels

    NARCIS (Netherlands)

    Trigueros-Motos, Laia; van Capelleveen, Julian C.; Torta, Federico; Castaño, David; Zhang, Lin-Hua; Chai, Ee Chu; Kang, Martin; Dimova, Lidiya G.; Schimmel, Alinda W. M.; Tietjen, Ian; Radomski, Chris; Tan, Liang Juin; Thiam, Chung Hwee; Narayanaswamy, Pradeep; Wu, Daniel Heqing; Dorninger, Fabian; Yakala, Gopala Krishna; Barhdadi, Amina; Angeli, Veronique; Dubé, Marie-Pierre; Berger, Johannes; Dallinga-Thie, Geesje M.; Tietge, Uwe J. F.; Wenk, Markus R.; Hayden, Michael R.; Hovingh, G. Kees; Singaraja, Roshni R.

    2017-01-01

    Objective-High-density lipoproteins (HDL) are considered to protect against atherosclerosis in part by facilitating the removal of cholesterol from peripheral tissues. However, factors regulating lipid efflux are incompletely understood. We previously identified a variant in adenosine

  8. Ultrasound Imaging of Muscle Contraction of the Tibialis Anterior in Patients with Facioscapulohumeral Dystrophy

    NARCIS (Netherlands)

    Gijsbertse, Kaj; Goselink, Rianne; Lassche, Saskia; Nillesen, Maartje; Sprengers, André; Verdonschot, Nico; van Alfen, Nens; de Korte, Chris

    2017-01-01

    A need exists for biomarkers to diagnose, quantify and longitudinally follow facioscapulohumeral muscular dystrophy (FSHD) and many other neuromuscular disorders. Furthermore, the pathophysiological mechanisms leading to muscle weakness in most neuromuscular disorders are not completely understood.

  9. Volatile sulphur compounds in morning breath of human volunteers

    NARCIS (Netherlands)

    Snel, Johannes; Burgering, Maurits; Smit, Bart; Noordman, Wouter; Tangerman, Albert; Winkel, Edwin G.; Kleerebezem, Michiel

    Objective: Morning breath contains elevated concentrations of volatile sulphur components (VSCs). Therefore, morning breath is recognised as a surrogate target for interventions on breath quality. Nevertheless, factors influencing morning breath are poorly understood. Our aim was to evaluate

  10. Volatile sulphur compounds in morning breath of human volunteers.

    NARCIS (Netherlands)

    Snel, J.; Burgering, M.; Smit, B.; Noordman, W.; Tangerman, A.; Winkel, E.G.; Kleerebezem, M.

    2011-01-01

    OBJECTIVE: morning breath contains elevated concentrations of volatile sulphur components (VSCs). Therefore, morning breath is recognised as a surrogate target for interventions on breath quality. Nevertheless, factors influencing morning breath are poorly understood. Our aim was to evaluate

  11. Wheat streak mosaic virus coat protein is a host-specific long-distance transport determinant in oat

    Science.gov (United States)

    Viral determinants involved in systemic infection of hosts by monocot-infecting plant viruses are poorly understood. Wheat streak mosaic virus (WSMV, genus Tritimovirus, family Potyviridae) exclusively infects monocotyledonous crops such as wheat, oat, barley, maize, triticale, and rye. Previously, ...

  12. Biodiversity and species competition regulate the resilience of microbial biofilm community

    DEFF Research Database (Denmark)

    Feng, Kai; Zhang, Zhaojing; Cai, Weiwei

    2017-01-01

    The relationship between biodiversity and ecosystem stability is poorly understood in microbial communities. Biofilm communities in small bioreactors called microbial electrolysis cells (MEC) contain moderate species numbers and easy tractable functional traits, thus providing an ideal platform f...

  13. Osteoprotegerin mediates tumor-promoting effects of Interleukin-1beta in breast cancer cells

    NARCIS (Netherlands)

    Chung, S.T.M. (Stephanie Tsang Mui); D. Geerts (Dirk); Roseman, K. (Kim); Renaud, A. (Ashleigh); Connelly, L. (Linda)

    2017-01-01

    markdownabstract__Background:__ It is widely recognized that inflammation promotes breast cancer invasion and metastasis. Given the complex nature of the breast tumor inflammatory microenvironment, much remains to be understood of the molecular mechanisms that govern these effects. We have

  14. Dendritic calcium activity precedes inspiratory bursts in preBotzinger complex neurons

    DEFF Research Database (Denmark)

    Del Negro, Christopher A; Hayes, John A; Rekling, Jens C

    2011-01-01

    Medullary interneurons of the preBötzinger complex assemble excitatory networks that produce inspiratory-related neural rhythms, but the importance of somatodendritic conductances in rhythm generation is still incompletely understood. Synaptic input may cause Ca(2+) accumulation postsynaptically ...

  15. EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival

    NARCIS (Netherlands)

    Smits, Michiel; van Rijn, Sjoerd; Hulleman, Esther; Biesmans, Dennis; van Vuurden, Dannis G.; Kool, Marcel; Haberler, Christine; Aronica, Eleonora; Vandertop, W. Peter; Noske, David P.; Würdinger, Thomas

    2012-01-01

    Purpose: Medulloblastoma is the most common malignant brain tumor in children. Despite recent improvements, the molecular mechanisms driving medulloblastoma are not fully understood and further elucidation could provide cues to improve outcome prediction and therapeutic approaches. Experimental

  16. Comet Hitchhiker: Harvesting Kinetic Energy from Small Bodies to Enable Fast and Low-Cost Deep Space Exploration

    Data.gov (United States)

    National Aeronautics and Space Administration — This idea can be intuitively understood by the analogy of fishing. Imagine a fisherman on a small boat tries to catch a big fish that runs at a high relative speed....

  17. What can flux tracking teach us about water age distribution patterns and their temporal dynamics?

    NARCIS (Netherlands)

    Hrachowitz, M.; Savenije, H.; Bogaard, T.A.; Tetzlaff, D.; Soulsby, C.

    2013-01-01

    The complex interactions of runoff generation processes underlying the hydrological response of streams remain not entirely understood at the catchment scale. Extensive research has demonstrated the utility of tracers for both inferring flow path distributions and constraining model

  18. Altitudinal divergence in maternal thermoregulatory behaviour may be driven by differences in selection on offspring survival in a viviparous lizard

    NARCIS (Netherlands)

    Uller, Tobias; While, Geoffrey M.; Cadby, Chloe D.; Harts, Anna; O'Connor, Katherine; Pen, Ido; Wapstra, Erik

    Plastic responses to temperature during embryonic development are common in ectotherms, but their evolutionary relevance is poorly understood. Using a combination of field and laboratory approaches, we demonstrate altitudinal divergence in the strength of effects of maternal thermal opportunity on

  19. Inhalation Exposure and Lung Dose Analysis of Multi-mode Complex Ambient Aerosols

    Science.gov (United States)

    Rationale: Ambient aerosols are complex mixture of particles with different size, shape and chemical composition. Although they are known to cause health hazard, it is not fully understood about causal mechanisms and specific attributes of particles causing the effects. Internal ...

  20. Fainting during Urination (Micturition Syncope): What Causes It?

    Science.gov (United States)

    ... urinating. His doctor said he might have micturition syncope. What causes this, and what can he do about it? ... at night after a deep sleep. The exact cause of micturition syncope isn't fully understood. But it may be ...

  1. Prices and Politics in Andean Water Reforms

    NARCIS (Netherlands)

    Boelens, R.A.; Zwarteveen, M.Z.

    2005-01-01

    Water rights are best understood as politically contested and culturally embedded relationships among different social actors. In the Andean region, existing rights of irrigators¿ collectives often embody historical struggles over resources, rules, authorities and identities. This article argues,

  2. Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?

    DEFF Research Database (Denmark)

    Bagger, Y Z; Rasmussen, Henrik Berg; Alexandersen, P

    2007-01-01

    Epidemiological observations suggest links between osteoporosis and risk of acute cardiovascular events and vice versa. Whether the two clinical conditions are linked by common pathogenic factors or atherosclerosis per se remains incompletely understood. We investigated whether serum lipids...

  3. Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

    DEFF Research Database (Denmark)

    Wibroe, Peter Popp; Anselmo, Aaron C; Nilsson, Per H

    2017-01-01

    Intravenously injected nanopharmaceuticals, including PEGylated nanoparticles, induce adverse cardiopulmonary reactions in sensitive human subjects, and these reactions are highly reproducible in pigs. Although the underlying mechanisms are poorly understood, roles for both the complement system ...

  4. Classical antiparticles

    International Nuclear Information System (INIS)

    Costella, J.P.; McKellar, B.H.J.; Rawlinson, A.A.

    1997-03-01

    We review how antiparticles may be introduced in classical relativistic mechanics, and emphasize that many of their paradoxical properties can be more transparently understood in the classical than in the quantum domain. (authors)

  5. Nanoplasmonics: Exploring nonlocal and quantum effects

    DEFF Research Database (Denmark)

    Mortensen, N. Asger

    2016-01-01

    Plasmonics is commonly understood within classical electrodynamics with local-response constitutive relations. However, possibilities for nonlocal dynamics and quantum effects emerge with strong spatial confinement in plasmonic nanostructures. This talks reviews recent theory and experiments...

  6. Damage Assessment in TiB2 Ceramic Armor Targets

    National Research Council Canada - National Science Library

    Rupert, Nevin

    2001-01-01

    The interaction between long rods and ceramics is only partially understood; however, this understanding is essential in the design of improved performance of impact-resistant materials and armor system design applications...

  7. Immunity to parasitic infection

    National Research Council Canada - National Science Library

    Lamb, Tracey J

    2012-01-01

    .... Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system...

  8. Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice

    NARCIS (Netherlands)

    Steegenga, Wilma T; Mischke, Mona; Lute, Carolien; Boekschoten, Mark V; Pruis, Maurien Gm; Lendvai, Agnes; Verkade, Henkjan J; Boekhorst, Jos; Timmerman, Harro M; Plösch, Torsten; Müller, Michael

    2014-01-01

    Background: There is increasing appreciation for sexually dimorphic effects, but the molecular mechanisms underlying these effects are only partially understood. In the present study, we explored transcriptomics and epigenetic differences in the small intestine and colon of prepubescent male and

  9. Symptoms and Treatment of Depression

    Medline Plus

    Full Text Available ... fighting, fighting. NARRATOR : Depression is a real and complex illness that is not yet completely understood. We ... antidepressants more effective in treating youth anxiety disorder, analysis shows 'Filter' hones GWAS results to help researchers ...

  10. Pathways of lipid vesicle deposition on solid surfaces : A combined QCM-D and AFM study

    NARCIS (Netherlands)

    Richter, R; Mukhopadhyay, A; Brisson, A

    2003-01-01

    Supported lipid bilayers (SLBs) are popular models of cell membranes with potential biotechnological applications, yet the mechanism of SLB formation is only partially understood. In this study, the adsorption and subsequent conformational changes of sonicated unilamellar vesicles on silica supports

  11. The Role of Small Cities in Shaping Youth Employment Outcomes in ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    economic development is not well understood. This research project will address this gap by exploring how small cities can shape employment outcomes for migrant youth, specifically for women and youth from non-metropolitan backgrounds.

  12. Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus

    DEFF Research Database (Denmark)

    Østergaard, Ole; Nielsen, Christoffer Tandrup; Tanassi, Julia Tanas

    2017-01-01

    BACKGROUND: The pathogenesis of systemic lupus erythematosus (SLE) is poorly understood but has been linked to defective clearance of subcellular particulate material from the circulation. This study investigates the origin, formation, and specificity of circulating microparticles (MPs) in patients...

  13. Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity

    DEFF Research Database (Denmark)

    Albrechtsen, Reidar; Hansen, Dorte Stautz; Sanjay, Archana

    2011-01-01

    Invadopodia are dynamic actin structures at the cell surface that degrade extracellular matrix and act as sites of signal transduction. The biogenesis of invadopodia, including the mechanisms regulating their formation, composition, and turnover is not entirely understood. Here, we demonstrate...

  14. Validating commercial remote sensing and spatial information (CRS&SI) technologies for streamlining environmental and planning processes in transportation projects.

    Science.gov (United States)

    2010-03-01

    Transportation corridor-planning processes are well understood, and consensus exists among practitioners : about common practices for stages and tasks included in traditional EIS approaches. However, traditional approaches do : not typically employ f...

  15. Implementation of Automation for Control of Robotic Systems

    National Research Council Canada - National Science Library

    Cosenzo, Keryl A; Parasuraman, Raja; Novak, Anthony; Barnes, Michael

    2006-01-01

    .... The role of the human operator in the human-robot environment is not well understood; however, most contemplated systems will require active human control or supervision with the possibility of intervention...

  16. Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47

    DEFF Research Database (Denmark)

    Kamstra, Jorke H; Hruba, Eva; Blumberg, Bruce

    2014-01-01

    . The mechanisms by which EDCs direct preadipocytes to form adipocytes are poorly understood. Here, we examined transcriptional and epigenetic mechanisms underlying the induction of in vitro adipocyte differentiation by BDE-47. Quantitative high content microscopy revealed concentration-dependent enhanced...

  17. Enhanced expression of fibroblast growth factors and receptor FGFR-1 during vascular remodeling in chronic obstructive pulmonary disease

    NARCIS (Netherlands)

    A.R. Kranenburg (Andor); W.I. de Boer (Pim); J.H.J.M. van Krieken (Han); W.J. Mooi (Wolter); J.E. Walters (Jane); P.R. Saxena (Pramod Ranjan); P.J. Sterk (Peter); H.S. Sharma (Hari)

    2002-01-01

    textabstractImportant characteristics of chronic obstructive pulmonary disease (COPD) include airway and vascular remodeling, the molecular mechanisms of which are poorly understood. We assessed the role of fibroblast growth factors (FGF) in pulmonary vascular remodeling by

  18. Tracking of Fluid-Advected Odor Plumes: Strategies Inspired by Insect Orientation to Pheromone

    National Research Council Canada - National Science Library

    Li, Wei

    2002-01-01

    .... These strategies are inspired by the maneuvers of moths flying upwind along a pheromone plume. Although moth maneuvers are well documented, the mechanisms underlying sensory perception and navigation are not fully understood...

  19. Improved Wetland Mapping Through the use of Advanced Geospatial Technologies

    Science.gov (United States)

    For the United States to effectively manage its remaining wetlands, their abundance, distribution, boundaries, and inherent characteristics must be better understood. As natural resource management becomes more holistic and moves towards ecosystem management, the synoptic view that remotely sensed d...

  20. Cultural antecedents of feeling lonely : Individualism, collectivism, and loneliness in Austria

    NARCIS (Netherlands)

    Heu, Luzia; van Zomeren, Martijn; Hansen, Nina

    2017-01-01

    Feeling lonely is profoundly unhealthy, but poorly understood. We examined the cultural dimension of collectivism (vs. individualism) as a potential risk factor for loneliness. Generally, we expected loneliness to flow from perceived ideal-actual discrepancies regarding social relationship

  1. 75 FR 17771 - Comment Request for Information Collection for Jobs for Veterans Act Priority of Service...

    Science.gov (United States)

    2010-04-07

    ... requirement in conjunction with the implementation of the generic integrated reporting and performance..., reporting burden (time and financial resources) is minimized, collection instruments are clearly understood... 19, 2008, DOL had received OMB approval of the Workforce Investment Streamlined Performance Reporting...

  2. Occurrence of crystal arthropathy in patients presenting with ...

    African Journals Online (AJOL)

    musculo-skeletal) diseases associated with the deposition of mineralized material within joints and periarticular soft tissues. Gout is the most common and pathogenetically best understood crystal arthropathy, followed by basic calcium ...

  3. Right Time, Right Place : Probing the Functions of Organelle Positioning

    NARCIS (Netherlands)

    van Bergeijk, Petra; Hoogenraad, Casper C; Kapitein, Lukas C

    2016-01-01

    The proper spatial arrangement of organelles underlies many cellular processes including signaling, polarization, and growth. Despite the importance of local positioning, the precise connection between subcellular localization and organelle function is often not fully understood. To address this,

  4. Jesus: 'n Geloofsgeneser?

    Directory of Open Access Journals (Sweden)

    Johan Ayres

    1998-12-01

    Full Text Available Jesus: A faith-healer? How are we in a modern age to understand the healing wonders of Jesus in the gospel? How must exorcism be understood? The intention of this paper is to indicate that Jesus' exorcisms are to be understood against the background of the stress factors in the first-century Mediterranean world. The propaganda motive, as well as the competitive milieu in which the texts originated, must be kept in mind when interpreting the healings of Jesus. Jesus' exorcisms are embedded in the structure and institutions of his time. The various institutions in the first-century Mediterranean world must not be understood as separate from one another: they are in fact embedded in each other. The healings of Jesus should be understood as healings of empowerment. Jesus empowers people to cope. He gives authentic meaning to peoples' lives on account of their experience of God's presence.

  5. U.S. Domestic Cats as Sentinels for Perfluoroalkyl Substances: Possible Linkages with Housing, Obesity and Disease

    Science.gov (United States)

    Perfluoroalkyl substances (PFAS), such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) , are persistent, globally distributed, anthropogenic compounds. The primary source(s) for human exposure are not well understood although within home exposure is likely i...

  6. Street Smart: Intelligence Preparation of the Battlefield for Urban Operations

    National Research Council Canada - National Science Library

    Medby, Jamison

    2002-01-01

    .... The armed forces of the United States have long understood these prescriptions and have amassed an array of technologies, techniques, analytic methods, and talented personnel to ensure intelligence superiority...

  7. Transcriptome response to hormonal manipulation of follicle-enclosed oocytes in rainbow trout

    Science.gov (United States)

    Captive fish often display reproductive dysfunction associated with follicle maturation. Gonadotropins and the progestogen maturation-inducing hormones (MIH) are important regulators of follicle maturation; however, their actions including regulating follicle maturation are not fully understood. The...

  8. Statistical data analysis handbook

    National Research Council Canada - National Science Library

    Wall, Francis J

    1986-01-01

    It must be emphasized that this is not a text book on statistics. Instead it is a working tool that presents data analysis in clear, concise terms which can be readily understood even by those without formal training in statistics...

  9. Modeling safety culture as a socially emergent phenomenon: a case study in aircraft maintenance

    NARCIS (Netherlands)

    Passenier, D.F.; Mols, C.; Bím, J.; Sharpanskykh, A.

    2016-01-01

    Safety culture is often understood as encompassing organizational members’ shared attitudes, beliefs, perceptions and values associated with safety. Safety culture theory development is fraught with inconsistencies and superficiality of measurement methods, because the dynamic and political nature

  10. Using 1-D and 2-D J-resolved 1H-NMR metabolomics to understand the effects of anemia in channel catfish Ictalurus punctatus

    Science.gov (United States)

    Anemia is a widespread hematological disorder in vertebrates. In channel catfish (Ictalurus punctatus), anemia is a persistent problem in culture environments, however, its causes and physiological impacts are not well understood. To better understand the symptoms and characterize associated biomark...

  11. Using 1-D 1H and 2-D 1H J-resolved NMR metabolomics to understand the effects of anemia in channel catfish (Ictalurus punctatus)

    Science.gov (United States)

    Anemia is a widespread hematological disorder in vertebrates. In channel catfish (Ictalurus punctatus), anemia is a persistent problem in culture environments, however, its causes and physiological impacts are not well understood. To better understand the symptoms and characterize associated biomark...

  12. Development, Social Citizenship and Human Rights: Re-thinking the ...

    African Journals Online (AJOL)

    , namely that of a neo-colonial process, development was understood and fought for in Africa as [part of] an emancipatory political project central to the liberatory vision of the pan-African nationalism which emerged victorious at independence.

  13. Childhood trauma and childhood urbanicity in relation to psychotic disorder

    NARCIS (Netherlands)

    Frissen, Aleida; Lieverse, Ritsaert; Drukker, Marjan; van Winkel, Ruud; Delespaul, Philippe; Bruggeman, Richard; Cahn, Wiepke; de Haan, Lieuwe; Kahn, René; Meije, Carin; Myin-Germeys, Inez; van Os, Jim; Wiersma, Durk

    2015-01-01

    Urban upbringing and childhood trauma are both associated with psychotic disorders. However, the association between childhood urbanicity and childhood trauma in psychosis is poorly understood. The urban environment could occasion a background of social adversity against which any effect of

  14. Childhood trauma and childhood urbanicity in relation to psychotic disorder

    NARCIS (Netherlands)

    Frissen, Aleida; Lieverse, Ritsaert; Drukker, Marjan; van Winkel, Ruud; Delespaul, Philippe; Cahn, W

    2015-01-01

    BACKGROUND: Urban upbringing and childhood trauma are both associated with psychotic disorders. However, the association between childhood urbanicity and childhood trauma in psychosis is poorly understood. The urban environment could occasion a background of social adversity against which any effect

  15. Antibacterials in Household Products

    Science.gov (United States)

    ... yet fully understood. It has been recovered from lake sediment, rivers, streams, wastewater, seawater, and has been found in fish bile, aquatic biota, human breast milk, and blood ... with running water, followed by thorough drying, is still considered the ...

  16. RELATIONSHIP BETWEEN ETHINYLESTRADIOL-MEDIATED CHANGES IN ENDOCRINE FUNCTION AND REPRODUCTION IMPAIRMENT IN JAPANESE MEDAKA (ORYZIAS LATIPES)

    Science.gov (United States)

    Many biochemical endpoints currently are used to describe endocrine function in fish; however, the sensitivity of these parameters as biomarkers of impaired reproduction or sexual development is not well understood. In the present study, adult Japanese medaka (Oryzias latipes) we...

  17. Forcing of a photochemical air quality model with atmospheric fields simulated by a regional climate model

    CSIR Research Space (South Africa)

    Naidoo, M

    2010-10-01

    Full Text Available Within the context of climate change over southern Africa, little is understood about the potential local response of air quality to changes in the larger scale environment. Under future climate forcing, there may be significant changes...

  18. Gauging the Commitment of Clandestine Group Members

    National Research Council Canada - National Science Library

    Downs, Doneda D

    2006-01-01

    .... Until a few years ago, most research on individual commitment and organizational cohesion has been based primarily on questionnaires and open observations on groups that desire to be understood...

  19. Predictive Maintenance--An Effective Money Saving Tool Being Applied in Industry Today.

    Science.gov (United States)

    Smyth, Tom

    2000-01-01

    Looks at preventive/predictive maintenance as it is used in industry. Discusses core preventive maintenance tools that must be understood to prepare students. Includes a list of websites related to the topic. (JOW)

  20. Small intestine epithelial barrier function is compromised in pigs with low feed intake at weaning.

    NARCIS (Netherlands)

    Spreeuwenberg, M.A.; Verdonk, J.M.; Gaskins, H.R.; Verstegen, M.W.A.

    2001-01-01

    Compromising alterations in gastrointestinal architecture are common during the weaning transition of pigs. The relation between villous atrophy and epithelial barrier function at weaning is not well understood. This study evaluated in vitro transepithelial transport by Ussing metabolic chambers,