WorldWideScience

Sample records for underlying costs prohibit

  1. Norplant's high cost may prohibit use in Title 10 clinics.

    Science.gov (United States)

    1991-04-01

    The article discusses the prohibitive cost of Norplant for the Title 10 low-income population served in public family planning clinics in the U.S. It is argued that it's unfair for U.S. users to pay $350 to Wyeth- Ayerst when another pharmaceutical company provides developing countries with Norplant at a cost of $14 - 23. Although the public sector and private foundations funded the development, it was explained that the company needs to recoup the investment in training and education. Medicaid and third party payers such as insurance companies will reimburse for the higher price, but if the public sector price is lowered, then the company would not make a profit and everyone would have argued for the reimbursement at the lower cost. It was suggested that a boycott of American Home Products, Wyeth-Ayerst's parent company, be made. Public family planning providers who are particularly low in funding reflect that their budget of $30,000 would only provide 85 users, and identified in this circumstance by drug abusers and multiple pregnancy women, and the need for teenagers remains unfulfilled. Another remarked that the client population served is 4700 with $54,000 in funding, which is already accounted for. The general trend of comments was that for low income women the cost is to high.

  2. 12 CFR 585.100 - Who is exempt from the prohibition under this part?

    Science.gov (United States)

    2010-01-01

    ... TREASURY PROHIBITED SERVICE AT SAVINGS AND LOAN HOLDING COMPANIES Exemptions § 585.100 Who is exempt from the prohibition under this part? (a) Employees. An employee of a savings and loan holding company is..., or public utilities operations. (2) The savings and loan holding company maintains a list of all...

  3. Robotic and endoscopic transaxillary thyroidectomies may be cost prohibitive when compared to standard cervical thyroidectomy: a cost analysis.

    Science.gov (United States)

    Cabot, Jennifer C; Lee, Cho Rok; Brunaud, Laurent; Kleiman, David A; Chung, Woong Youn; Fahey, Thomas J; Zarnegar, Rasa

    2012-12-01

    This study presents a cost analysis of the standard cervical, gasless transaxillary endoscopic, and gasless transaxillary robotic thyroidectomy approaches based on medical costs in the United States. A retrospective review of 140 patients who underwent standard cervical, transaxillary endoscopic, or transaxillary robotic thyroidectomy at 2 tertiary centers was conducted. The cost model included operating room charges, anesthesia fee, consumables cost, equipment depreciation, and maintenance cost. Sensitivity analyses assessed individual cost variables. The mean operative times for the standard cervical, transaxillary endoscopic, and transaxillary robotic approaches were 121 ± 18.9, 185 ± 26.0, and 166 ± 29.4 minutes, respectively. The total cost for the standard cervical, transaxillary endoscopic, and transaxillary robotic approaches were $9,028 ± $891, $12,505 ± $1,222, and $13,670 ± $1,384, respectively. Transaxillary approaches were significantly more expensive than the standard cervical technique (standard cervical/transaxillary endoscopic, P cost when transaxillary endoscopic operative time decreased to 111 minutes and transaxillary robotic operative time decreased to 68 minutes. Increasing the case load did not resolve the cost difference. Transaxillary endoscopic and transaxillary robotic thyroidectomies are significantly more expensive than the standard cervical approach. Decreasing operative times reduces this cost difference. The greater expense may be prohibitive in countries with a flat reimbursement schedule. Copyright © 2012 Mosby, Inc. All rights reserved.

  4. 40 CFR 80.385 - What acts are prohibited under the gasoline sulfur program?

    Science.gov (United States)

    2010-07-01

    ... gasoline sulfur program? 80.385 Section 80.385 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Violation Provisions § 80.385 What acts are prohibited under the gasoline sulfur program? No person shall: (a...

  5. 40 CFR 80.1005 - What acts are prohibited under the gasoline toxics program?

    Science.gov (United States)

    2010-07-01

    ... gasoline toxics program? 80.1005 Section 80.1005 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Violation Provisions § 80.1005 What acts are prohibited under the gasoline toxics program? No person shall: (a...

  6. 50 CFR 216.16 - Prohibitions under the General Authorization for Level B harassment for scientific research.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Prohibitions under the General Authorization for Level B harassment for scientific research. 216.16 Section 216.16 Wildlife and Fisheries... Prohibitions under the General Authorization for Level B harassment for scientific research. It shall be...

  7. A Cost-Effectiveness Analysis of India’s 2008 Prohibition of Smoking in Public Places in Gujarat

    Directory of Open Access Journals (Sweden)

    Bhavesh Modi

    2011-04-01

    Full Text Available Tobacco smoking and exposure to secondhand tobacco smoke are associated with disability and premature mortality in low and middle-income countries. The aim of this study was to assess the cost-effectiveness of implementing India’s Prohibition of Smoking in Public Places Rules in the state of Gujarat, compared to implementation of a complete smoking ban. Using standard cost-effectiveness analysis methods, the cost of implementing the alternatives was evaluated against the years of life saved and cases of acute myocardial infarction averted by reductions in smoking prevalence and secondhand smoke exposure. After one year, it is estimated that a complete smoking ban in Gujarat would avert 17,000 additional heart attacks and gain 438,000 life years (LY. A complete ban is highly cost-effective when key variables including legislation effectiveness were varied in the sensitivity analyses. Without including medical treatment costs averted, the cost-effectiveness ratio ranges from $2 to $112 per LY gained and $37 to $386 per acute myocardial infarction averted. Implementing a complete smoking ban would be a cost saving alternative to the current partial legislation in terms of reducing tobacco-attributable disease in Gujarat.

  8. Frequent price changes under menu costs

    DEFF Research Database (Denmark)

    Hansen, Per Svejstrup

    1999-01-01

    , the price may be changed more frequent in the short run, and in the long run it definitely will. Hence, observing frequent price changes is not necessarily inconsistent with a firm operating under menu costs. This paper relies on an article by Dixit (1991), (Review of Economic studies, 58, 141......This paper investigates the effect of uncertainty on a single firm's pricing behaviour in a dynamic menu cost model that results in (S,s)-rules where the price is fixed inside a band. It will be demonstrated that even though the band of inaction widens in response to increased uncertainty...

  9. Attitudes of cannabis growers to regulation of cannabis cultivation under a non-prohibition cannabis model.

    Science.gov (United States)

    Lenton, Simon; Frank, Vibeke A; Barratt, Monica J; Dahl, Helle Vibeke; Potter, Gary R

    2015-03-01

    How cannabis cultivation is dealt with under various examples of cannabis legalization or regulation is an important consideration in design of such schemes. This study aimed to (i) investigate support among current or recent cannabis growers, for various potential policy options for cannabis cultivation if prohibition were repealed, and (ii) explore the support for these options across countries, scale of growing operations, demographics, drug use and cannabis supply involvement variables. This study utilized data from the online web survey of largely 'small-scale' cannabis cultivators, aged 18yrs and over, in eleven countries conducted by the Global Cannabis Cultivation Research Consortium (GCCRC). Data from 1722 current and recent cannabis growers in Australia, Denmark and the UK, who were all asked about policy, were included in the analysis. It investigated support for various frameworks for cultivation: (no regulation (free market); adult only; growing licenses; restrictions on plant numbers; licensed business-only sale; approved commercial growing; etc.). Among current growers, support for these options were compared across countries, across scale of growing operations, and by demographics, drug use and crime variables. Although there were some between country differences in support for the various policy options, what was striking was the similarity of the proportions for each of the eight most popular policy options. Among current growers, many of these positions were predicted by demographic, drug use and cannabis growing variables which were conceptually congruent with these positions. The results have relevance for the provisions regarding cannabis cultivation in the design of new non-prohibitionist models of cannabis which are increasingly under consideration. It should be of interest to policy makers, drug policy researchers, law enforcement and cannabis cultivators. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. External costs of electricity production under scrutiny

    International Nuclear Information System (INIS)

    Wagner, H.J.; Melchert, A.

    1993-01-01

    After a short introduction into the problems and questions surrounding the issue of external costs Chapter 2 presents the most important results of the studies under review and analysis in this work. Occasionally, minor discrepancies were found between the results given in the summary of a study and the data reported in the relevant chapters. Chapter 3 identifies and discusses differences in perspective between the studies under consideration. Chapter 4 analyses the most important premises and parameters adopted in the studies for the calculation of overall costs and net benefits of the different modes of electricity production. This serves to probe the reliability of the data, plausibility of the premises, and nature of the presupposed relationships. Chapter 5 examines the relationships of time assumed in the studies and gives a first comment on the more advanced Prognos study. Chapter 6, finally, offers a summarizing evaluation. (orig./UA) [de

  11. THE COST OF PRODUCTION UNDER DIRECT COSTING AND ABSORPTION COSTING – A COMPARATIVE APPROACH

    Directory of Open Access Journals (Sweden)

    Bunea-Bontaş Cristina Aurora

    2013-04-01

    Full Text Available Managerial accounting has an important role in strategic management of a company, being designed especially for managers, in order to optimise their decision regarding operating activities. One of the objectives of managerial accounting is the cost calculation, for measuring inventory costs, and the costs and profitability of products and services. Cost calculation systems can vary in terms of which costs are assigned to cost objects, two significant calculation systems being adopted by the costing theory: full cost accounting, which includes all costs of production as product costs, and partial cost accounting, which includes only those costs that vary with output. This article provides a comparative approach regarding the differences between the calculation of the cost of production under direct costing and absorption costing. It also examines the implication of using each of these calculation systems on the financial position and financial performance of the companies reported on the statement of financial position and the income statement. Finally, the advantages of using direct costing for internal reporting are discussed, considering that this method is not acceptable for external reporting to stockholders and other external users.

  12. Maintenance cost models in deregulated power systems under opportunity costs

    International Nuclear Information System (INIS)

    Al-Arfaj, K.; Dahal, K.; Azaiez, M.N.

    2007-01-01

    In a centralized power system, the operator is responsible for scheduling maintenance. There are different types of maintenance, including corrective maintenance; predictive maintenance; preventive maintenance; and reliability-centred maintenance. The main cause of power failures is poor maintenance. As such, maintenance costs play a significant role in deregulated power systems. They include direct costs associated with material and labor costs as well as indirect costs associated with spare parts inventory, shipment, test equipment, indirect labor, opportunity costs and cost of failure. In maintenance scheduling and planning, the cost function is the only component of the objective function. This paper presented the results of a study in which different components of maintenance costs were modeled. The maintenance models were formulated as an optimization problem with single and multiple objectives and a set of constraints. The maintenance costs models could be used to schedule the maintenance activities of power generators more accurately and to identify the best maintenance strategies over a period of time as they consider failure and opportunity costs in a deregulated environment. 32 refs., 4 tabs., 4 figs

  13. 77 FR 54482 - Allocation of Costs Under the Simplified Methods

    Science.gov (United States)

    2012-09-05

    ... cost of goods sold cash or trade discounts that taxpayers do not capitalize for book purposes (and... to adjust additional section 263A costs for cash or trade discounts described in Sec. 1.471-3(b... Allocation of Costs Under the Simplified Methods AGENCY: Internal Revenue Service (IRS), Treasury. ACTION...

  14. Determining the Effect (the Social Costs) of Exclusion under the ...

    African Journals Online (AJOL)

    Determining the Effect (the Social Costs) of Exclusion under the South African Exclusionary Rule: Should Factual Guilt Tilt the Scales in Favour of the Admission of Unconstitutionally Obtained Evidence?

  15. Costs of Tractor Ownership under Different Management Systems in ...

    African Journals Online (AJOL)

    Costs of Tractor Ownership under Different Management Systems in Nigeria. ... It requires high initial capital investment. ... making management plans and decisions especially in comparing different tractor types and models thereby assisting ...

  16. Wildfire Suppression Costs for Canada under a Changing Climate.

    Directory of Open Access Journals (Sweden)

    Emily S Hope

    Full Text Available Climate-influenced changes in fire regimes in northern temperate and boreal regions will have both ecological and economic ramifications. We examine possible future wildfire area burned and suppression costs using a recently compiled historical (i.e., 1980-2009 fire management cost database for Canada and several Intergovernmental Panel on Climate Change (IPCC climate projections. Area burned was modelled as a function of a climate moisture index (CMI, and fire suppression costs then estimated as a function of area burned. Future estimates of area burned were generated from projections of the CMI under two emissions pathways for four General Circulation Models (GCMs; these estimates were constrained to ecologically reasonable values by incorporating a minimum fire return interval of 20 years. Total average annual national fire management costs are projected to increase to just under $1 billion (a 60% real increase from the 1980-2009 period under the low greenhouse gas emissions pathway and $1.4 billion (119% real increase from the base period under the high emissions pathway by the end of the century. For many provinces, annual costs that are currently considered extreme (i.e., occur once every ten years are projected to become commonplace (i.e., occur once every two years or more often as the century progresses. It is highly likely that evaluations of current wildland fire management paradigms will be necessary to avoid drastic and untenable cost increases as the century progresses.

  17. Marginal ambulatory teaching cost under varying levels of service utilization.

    Science.gov (United States)

    Panton, D M; Mushlin, A I; Gavett, J W

    1980-06-01

    The ambulatory component of residency training jointly produces two products, namely, training and patient services. In costing educational programs of this type, two approaches are frequently taken. The first considers the total costs of the educational program, including training and patient services. These costs are usually constructed from historical accounting records. The second approach attempts to cost the joint products separately, based upon estimates of future changes in program costs, if the product in question is added to or removed from the program. The second approach relates to typical decisions facing the managers of medical centers and practices used for teaching purposes. This article reports such a study of costs in a primary-care residency training program in a hospital outpatient setting. The costs of the product, i.e., on-the-job training, are evaluated using a replacement-cost concept under different levels of patient services. The results show that the cost of the product, training, is small at full clinical utilization and is sensitive to changes in the volume of services provided.

  18. Currency Integration under Labor Mobility: when Cost is incurred

    OpenAIRE

    Yoshimi, Taiyo

    2014-01-01

    We assess whether renouncing monetary policy autonomy becomes a cost of currency integration under labor mobility in the framework of the New Open Economy Macroeconomics. Assuming Nash equilibrium among central banks of candidate countries, we find that the forfeiture of monetary policy autonomy becomes a cost when country-specific total factor productivity shocks hit them, labor input weights differ between candidate countries, and country specific shocks on marginal disutility of labor occu...

  19. Tariff Policy and Transport Costs under Reciprocal Dumping

    OpenAIRE

    Jun Oshiro

    2011-01-01

    This paper analyzes tariff competition by investigating the strategic interactions among firms that are highly mobile across national boundaries. Although high transport costs yield a geographic dispersion of the industry, sufficiently low transport costs result in a core-periphery location where nobody bears tariff burdens. In any case, the world economy would be in a much better position under an international coordination scheme. An economy is only required to enforce a weak international ...

  20. Cost-effective conservation of an endangered frog under uncertainty.

    Science.gov (United States)

    Rose, Lucy E; Heard, Geoffrey W; Chee, Yung En; Wintle, Brendan A

    2016-04-01

    How should managers choose among conservation options when resources are scarce and there is uncertainty regarding the effectiveness of actions? Well-developed tools exist for prioritizing areas for one-time and binary actions (e.g., protect vs. not protect), but methods for prioritizing incremental or ongoing actions (such as habitat creation and maintenance) remain uncommon. We devised an approach that combines metapopulation viability and cost-effectiveness analyses to select among alternative conservation actions while accounting for uncertainty. In our study, cost-effectiveness is the ratio between the benefit of an action and its economic cost, where benefit is the change in metapopulation viability. We applied the approach to the case of the endangered growling grass frog (Litoria raniformis), which is threatened by urban development. We extended a Bayesian model to predict metapopulation viability under 9 urbanization and management scenarios and incorporated the full probability distribution of possible outcomes for each scenario into the cost-effectiveness analysis. This allowed us to discern between cost-effective alternatives that were robust to uncertainty and those with a relatively high risk of failure. We found a relatively high risk of extinction following urbanization if the only action was reservation of core habitat; habitat creation actions performed better than enhancement actions; and cost-effectiveness ranking changed depending on the consideration of uncertainty. Our results suggest that creation and maintenance of wetlands dedicated to L. raniformis is the only cost-effective action likely to result in a sufficiently low risk of extinction. To our knowledge we are the first study to use Bayesian metapopulation viability analysis to explicitly incorporate parametric and demographic uncertainty into a cost-effective evaluation of conservation actions. The approach offers guidance to decision makers aiming to achieve cost

  1. Vertical governance change and product differentiation under decreasing component costs

    NARCIS (Netherlands)

    Vermeulen, B.; Huisman, K.J.M.; Kok, de A.G.

    In deciding on whether and when to outsource component production, firms should consider the trade-off between total production costs and the ability to horizontally differentiate products. We study the outsourcing decision in a duopoly under decreasing but uncertain market rates for components,

  2. Vertical governance change and product differentiation under decreasing component costs

    NARCIS (Netherlands)

    Vermeulen, B.; Huisman, K.J.M.; Kok, A.G. de

    2015-01-01

    In deciding on whether and when to outsource component production, firms should consider the trade-off between total production costs and the ability to horizontally differentiate products. We study the outsourcing decision in a duopoly under decreasing but uncertain market rates for components,

  3. Cost recovery of congested infrastructure under market power

    NARCIS (Netherlands)

    Verhoef, Erik T.

    2017-01-01

    The Mohring–Harwitz (1962) theorem states that the degree of self-financing of congested infrastructure is equal to the elasticity of the capacity cost function in the optimum, so that under neutral scale economies exact self-financing applies. The theorem breaks down when the infrastructure is used

  4. Cost and lack of insurance coverage are prohibitive to having dental implants after resections for benign mandibular neoplasms.

    Science.gov (United States)

    Peacock, Zachary S; Ji, Yisi D

    2017-06-01

    To assess how often patients receive dental implants after mandibular resection for benign neoplasms and to determine barriers to completion of functional reconstruction. This was a retrospective cohort study of patients who underwent resection for benign mandibular neoplasms between 2005 and 2014. Demographic variables included age, sex, and race. Outcome variables include rates of implant placement, implant restoration, and reasons for not having implants. Fisher's exact test and odds ratios were calculated. In all, 52 subjects (age 47.1 ± 19.2 years) were included. Twenty (38.6%) received dental implants. Race was associated with the likelihood of receiving implants (P = .0302). African Americans (1/11, 9.1%) were least likely compared to all other racial groups to have implants (odds ratio = 0.1158; P = .035; 95% confidence interval 0.013-0.989). Caucasians (17/35, 48.6%) were 4.41 times more likely to receive implants compared to all other races (odds ratio = 4.41; 95% confidence interval 1.073-18.093; P = .038). Of the 20 patients who received implants, 10 went on to have dental prostheses. The most common reason for not having implants was cost (37.5% overall), cited by 50% of black and 16.7% of white patients. Patients do not typically go on to dental reconstruction after mandibular resection, with cost as a major barrier. African Americans were least likely to complete full reconstruction. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Optimal Investment Under Transaction Costs: A Threshold Rebalanced Portfolio Approach

    Science.gov (United States)

    Tunc, Sait; Donmez, Mehmet Ali; Kozat, Suleyman Serdar

    2013-06-01

    We study optimal investment in a financial market having a finite number of assets from a signal processing perspective. We investigate how an investor should distribute capital over these assets and when he should reallocate the distribution of the funds over these assets to maximize the cumulative wealth over any investment period. In particular, we introduce a portfolio selection algorithm that maximizes the expected cumulative wealth in i.i.d. two-asset discrete-time markets where the market levies proportional transaction costs in buying and selling stocks. We achieve this using "threshold rebalanced portfolios", where trading occurs only if the portfolio breaches certain thresholds. Under the assumption that the relative price sequences have log-normal distribution from the Black-Scholes model, we evaluate the expected wealth under proportional transaction costs and find the threshold rebalanced portfolio that achieves the maximal expected cumulative wealth over any investment period. Our derivations can be readily extended to markets having more than two stocks, where these extensions are pointed out in the paper. As predicted from our derivations, we significantly improve the achieved wealth over portfolio selection algorithms from the literature on historical data sets.

  6. Prostitution, disability and prohibition.

    Science.gov (United States)

    Thomsen, Frej Klem

    2015-06-01

    Criminalisation of prostitution, and minority rights for disabled persons, are important contemporary political issues. The article examines their intersection by analysing the conditions and arguments for making a legal exception for disabled persons to a general prohibition against purchasing sexual services. It explores the badness of prostitution, focusing on and discussing the argument that prostitution harms prostitutes, considers forms of regulation and the arguments for and against with emphasis on a liberty-based objection to prohibition, and finally presents and analyses three arguments for a legal exception, based on sexual rights, beneficence, and luck egalitarianism, respectively. It concludes that although the general case for and against criminalisation is complicated there is a good case for a legal exception. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  7. Purchasing motors under consideration of full-cost pricing

    International Nuclear Information System (INIS)

    Mauchle, P.; Ritz, Ch.

    2007-01-01

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at how full-cost pricing should be considered when purchasing electric motors. The authors consider it essential that the overall life-cycle costs are carefully considered. This also guarantees economical operation and enables users to avoid unexpected costs throughout the service life of the motor. The aim of this project was to provide industrial companies with suitable tools for calculating the overall life-cycle costs of motors at the time of their acquisition. These tools take the form of a sample 'Call for Tender' for motors along with software for calculating life-cycle costs. The factors involved, such as investment, installation costs, energy and environmental costs as well as operational, maintenance and disposal costs are examined.

  8. 47 CFR 27.1166 - Reimbursement under the Cost-Sharing Plan.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Reimbursement under the Cost-Sharing Plan. 27... § 27.1166 Reimbursement under the Cost-Sharing Plan. (a) Registration of reimbursement rights. Claims for reimbursement under the cost-sharing plan are limited to relocation expenses incurred on or after...

  9. Asset Prices and Trading Volume under Fixed Transactions Costs.

    Science.gov (United States)

    Lo, Andrew W.; Mamaysky, Harry; Wang, Jiang

    2004-01-01

    We propose a dynamic equilibrium model of asset prices and trading volume when agents face fixed transactions costs. We show that even small fixed costs can give rise to large "no-trade" regions for each agent's optimal trading policy. The inability to trade more frequently reduces the agents' asset demand and in equilibrium gives rise to a…

  10. 16 CFR 1025.68 - Prohibited communications.

    Science.gov (United States)

    2010-01-01

    ... not served on all parties; or (ii) Any oral communication concerning a matter in adjudication which is... oral or written ex parte communication relative to the merits of any proceedings under these Rules is a...) Prohibited oral ex parte communication. (i) If a prohibited oral ex parte communication is made to a decision...

  11. 14 CFR 120.31 - Prohibited drugs.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Prohibited drugs. 120.31 Section 120.31... AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM... Under § 91.147 of This Chapter and Safety-Sensitive Employees § 120.31 Prohibited drugs. (a) Each...

  12. 15 CFR 760.2 - Prohibitions.

    Science.gov (United States)

    2010-01-01

    ... refusal to do business under this section for a United States person to provide management, procurement... race, religion, sex, or national origin of any U.S. person. (d) Furnishing information about business... OR BOYCOTTS § 760.2 Prohibitions. (a) Refusals to do business. Prohibition Against Refusals To Do...

  13. 24 CFR 891.130 - Prohibited relationships.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Prohibited relationships. 891.130 Section 891.130 Housing and Urban Development Regulations Relating to Housing and Urban Development... Requirements § 891.130 Prohibited relationships. This section shall apply to capital advances under the Section...

  14. 24 CFR 6.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discrimination prohibited. 6.4... COMMUNITY DEVELOPMENT ACT OF 1974 General Provisions § 6.4 Discrimination prohibited. (a) Section 109... benefits of, or be subjected to discrimination under any program or activity funded in whole or in part...

  15. 49 CFR 27.7 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Discrimination prohibited. 27.7 Section 27.7... OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General § 27.7 Discrimination prohibited. (a... participation in, be denied the benefits of, or otherwise be subjected to discrimination under any program or...

  16. 29 CFR 32.12 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Discrimination prohibited. 32.12 Section 32.12 Labor Office... § 32.12 Discrimination prohibited. (a) General. (1) No qualified handicapped individual shall, on the basis of handicap, be subjected to discrimination in employment under any program or activity to which...

  17. 28 CFR 42.203 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Discrimination prohibited. 42.203 Section...) of the Justice System Improvement Act of 1979 § 42.203 Discrimination prohibited. (a) No person in... participation in, be denied the benefits of, be subjected to discrimination under, or denied employment in...

  18. 38 CFR 18.411 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Discrimination prohibited... Practices § 18.411 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any program or activity to which...

  19. 45 CFR 84.21 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discrimination prohibited. 84.21 Section 84.21... Discrimination prohibited. No qualified handicapped person shall, because a recipient's facilities are... in, or otherwise be subjected to discrimination under any program or activity to which this part...

  20. 24 CFR 8.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discrimination prohibited. 8.4... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT General Provisions § 8.4 Discrimination prohibited. (a) No... in, be denied the benefits of, or otherwise be subjected to discrimination under any program or...

  1. 5 CFR 900.404 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Discrimination prohibited. 900.404... § 900.404 Discrimination prohibited. (a) General. A person in the United States shall not, on the ground... be otherwise subjected to discrimination under, a program to which this subpart applies. (b) Specific...

  2. 34 CFR 104.11 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Discrimination prohibited. 104.11 Section 104.11... ASSISTANCE Employment Practices § 104.11 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any program or...

  3. 14 CFR 1251.103 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Discrimination prohibited. 1251.103 Section... OF HANDICAP General Provisions § 1251.103 Discrimination prohibited. (a) General. No qualified... of, or otherwise be subjected to discrimination under any program or activity which receives Federal...

  4. 18 CFR 705.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Discrimination... Discrimination prohibited. (a) General. No person in the United States shall, on the grounds of race, color, or... discrimination under, any program to which this part applies. (b) Specific discriminatory actions prohibited. (1...

  5. 7 CFR 15b.12 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Discrimination prohibited. 15b.12 Section 15b.12... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Employment Practices § 15b.12 Discrimination prohibited. (a... discrimination in employment under any program or activity receiving assistance from this Department. (2) A...

  6. 29 CFR 32.26 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Discrimination prohibited. 32.26 Section 32.26 Labor Office... RECEIVING FEDERAL FINANCIAL ASSISTANCE Accessibility § 32.26 Discrimination prohibited. No qualified... discrimination under any program or activity to which this part applies. ...

  7. 43 CFR 27.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Discrimination prohibited. 27.3 Section 27... ISSUED UNDER TITLE II OF PUBLIC LAW 93-153 § 27.3 Discrimination prohibited. (a) General. No person shall... through contractual or other arrangements, subject an individual to discrimination on the grounds of race...

  8. 29 CFR 32.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Discrimination prohibited. 32.4 Section 32.4 Labor Office of... FEDERAL FINANCIAL ASSISTANCE General Provisions § 32.4 Discrimination prohibited. (a) General. No... denied the benefits of, or otherwise be subjected to discrimination under any program or activity which...

  9. 7 CFR 15b.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Discrimination prohibited. 15b.4 Section 15b.4... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 15b.4 Discrimination prohibited. (a... in, be denied the benefits of, or otherwise be subjected to discrimination under any program or...

  10. 45 CFR 605.21 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 605.21 Section 605.21... Accessibility § 605.21 Discrimination prohibited. No qualified handicapped person shall, because a recipient's... from participation in, or otherwise be subjected to discrimination under any program or activity to...

  11. 7 CFR 15d.2 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Discrimination prohibited. 15d.2 Section 15d.2... THE UNITED STATES DEPARTMENT OF AGRICULTURE § 15d.2 Discrimination prohibited. (a) No agency, officer... participation in, deny the benefits of, or subject to discrimination any person in the United States under any...

  12. 28 CFR 42.520 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Discrimination prohibited. 42.520 Section...-Implementation of Section 504 of the Rehabilitation Act of 1973 Accessibility § 42.520 Discrimination prohibited... participation in, or otherwise subjected to discrimination under any program or activity receiving Federal...

  13. 10 CFR 1040.66 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Discrimination prohibited. 1040.66 Section 1040.66 Energy... Practices § 1040.66 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination employment under any program or activity to...

  14. 6 CFR 21.5 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Discrimination prohibited. 21.5 Section 21.5... FROM THE DEPARTMENT OF HOMELAND SECURITY § 21.5 Discrimination prohibited. (a) General. No person in... participation in, be denied the benefits of, or be otherwise subjected to discrimination under, any program to...

  15. 45 CFR 605.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 605.4 Section 605.4... Provisions § 605.4 Discrimination prohibited. (a) General. No qualified handicapped person shall, on the... subjected to discrimination under any program or activity which receives Federal financial assistance. (b...

  16. 10 CFR 1040.63 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Discrimination prohibited. 1040.63 Section 1040.63 Energy... Provisions § 1040.63 Discrimination prohibited. (a) General. No qualified handicapped person shall, on the... subjected to discrimination under any program or activity that receives Federal financial assistance from...

  17. 45 CFR 84.11 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discrimination prohibited. 84.11 Section 84.11... § 84.11 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any program or activity to which this...

  18. 5 CFR 900.704 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Discrimination prohibited. 900.704... Federally Assisted Programs of the Office of Personnel Management § 900.704 Discrimination prohibited. (a..., be denied the benefits of, or otherwise be subjected to discrimination under any program or activity...

  19. 10 CFR 19.32 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Discrimination prohibited. 19.32 Section 19.32 Energy... § 19.32 Discrimination prohibited. No person shall on the grounds of sex be excluded from participation in, be denied a license, be denied the benefit of, or be subjected to discrimination under any...

  20. 14 CFR 1251.200 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Discrimination prohibited. 1251.200 Section... OF HANDICAP Employment Practices § 1251.200 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any...

  1. 22 CFR 217.21 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discrimination prohibited. 217.21 Section 217... Discrimination prohibited. No qualified handicapped person shall, because a recipient's facilities within the... excluded from participation in, or otherwise be subjected to discrimination under any program or activity...

  2. 45 CFR 1110.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 1110.3 Section 1110.3... HUMANITIES GENERAL NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS § 1110.3 Discrimination prohibited. (a... from participation in, be denied the benefits of, or be otherwise subjected, to discrimination under...

  3. 14 CFR 1251.300 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Discrimination prohibited. 1251.300 Section... OF HANDICAP Accessibility § 1251.300 Discrimination prohibited. No qualified handicapped person shall... benefits of, be excluded from participation in, or otherwise be subjected to discrimination under any...

  4. 38 CFR 18.404 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Discrimination prohibited... Provisions § 18.404 Discrimination prohibited. (a) General. No qualified handicapped person shall, on the... subjected to discrimination under any program or activity which receives Federal financial assistance. (b...

  5. 7 CFR 15b.17 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Discrimination prohibited. 15b.17 Section 15b.17... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Accessibility § 15b.17 Discrimination prohibited. No... to discrimination under any program or activity receiving assistance from this Department. ...

  6. 29 CFR 501.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Discrimination prohibited. 501.4 Section 501.4 Labor... IMMIGRATION AND NATIONALITY ACT General Provisions § 501.4 Discrimination prohibited. (a) A person may not... discrimination against any person under paragraph (a) of this section will be investigated by the WHD. Where the...

  7. 45 CFR 605.11 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 605.11 Section 605.11... Employment Practices § 605.11 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any program or...

  8. 34 CFR 104.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Discrimination prohibited. 104.4 Section 104.4... ASSISTANCE General Provisions § 104.4 Discrimination prohibited. (a) General. No qualified handicapped person... otherwise be subjected to discrimination under any program or activitiy which receives Federal financial...

  9. 45 CFR 84.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discrimination prohibited. 84.4 Section 84.4... § 84.4 Discrimination prohibited. (a) General. No qualified handicapped person shall, on the basis of... discrimination under any program or activity which receives Federal financial assistance. (b) Discriminatory...

  10. 38 CFR 18.421 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Discrimination prohibited... Accessibility § 18.421 Discrimination prohibited. No qualified handicapped person shall, because a recipient's... from participation in, or otherwise be subjected to discrimination under any program or activity to...

  11. 34 CFR 104.21 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Discrimination prohibited. 104.21 Section 104.21... ASSISTANCE Accessibility § 104.21 Discrimination prohibited. No qualified handicapped person shall, because a... excluded from participation in, or otherwise be subjected to discrimination under any program or activity...

  12. 45 CFR 1203.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Discrimination prohibited. 1203.4 Section 1203.4... OF 1964 § 1203.4 Discrimination prohibited. (a) General. A person in the United States shall not, on... benefits of, or be otherwise subjected to discrimination under, a program to which this part applies. (b...

  13. 10 CFR 1040.71 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Discrimination prohibited. 1040.71 Section 1040.71 Energy... § 1040.71 Discrimination prohibited. No handicapped person shall, because a recipient's facilities are... in, or be subjected to discrimination under any program or activity that receives or benefits from...

  14. 49 CFR 21.5 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Discrimination prohibited. 21.5 Section 21.5... DEPARTMENT OF TRANSPORTATION-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 21.5 Discrimination... discrimination under, any program to which this part applies. (b) Specific discriminatory actions prohibited: (1...

  15. 22 CFR 217.11 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discrimination prohibited. 217.11 Section 217... Discrimination prohibited. (a) General. (1) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment under any program or activity to which this part applies. (2) A...

  16. 38 CFR 18.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Discrimination prohibited... THE CIVIL RIGHTS ACT OF 1964 General § 18.3 Discrimination prohibited. (a) General. No person in the..., be denied the benefits of, or be otherwise subjected to discrimination under any program to which...

  17. 14 CFR 271.9 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Discrimination prohibited. 271.9 Section... TRANSPORTATION § 271.9 Discrimination prohibited. (a) All air carriers receiving subsidy under this part shall comply with the following: (1) The Age Discrimination Act of 1975; (2) The Civil Rights Act of 1964 and...

  18. Integrated Cost Allocation of Transmission Usage under Electricity Markets

    Directory of Open Access Journals (Sweden)

    Hermagasantos Zein

    2012-08-01

    Full Text Available Cost allocation of transmission usage on the power networks is an important issue especially in the modern electricity market mechanism. In this context, all costs that have been embedded in the transmission, embedded cost, should be covered by the transmission users. This paper follows general methods, where generators are fullyresponsible to cover the embedded cost. It proposes a method to determine the cost allocation of transmission usage based on decomposition through the superposition techinique to determine power flow contributions from an integrated base case of the results of the power flow calculations of all transactions, bilateral and nonbilateral contracts. Mathematically, the applied formulations are illustrated clearly in this paper. The proposed method has been tested with 5-bus system and the results are much different compared to a few of the published methods. This is shown by the test results on the 5 bus system. The published methods produce total power flow contributions in each line is greater than the actual. And they earn total revenues approximately 11.6% greater than the embedded cost. While on the proposed method, the power flow contribu tions are equal to the actual and the revenues are equal to the embedded cost. It shows also that the proposed method gives results as expected.

  19. Economic Cost of Malaria Treatment under the Health Insurance ...

    African Journals Online (AJOL)

    The paper discusses the findings of a survey which explored the implications of ..... this framework, opportunity costs of work or loss of productivity are treated as ..... found in the informal sector, it would be imperative to introduce flexible pre-.

  20. 48 CFR 252.235-7001 - Indemnification under 10 U.S.C. 2354-cost reimbursement.

    Science.gov (United States)

    2010-10-01

    ....S.C. 2354-cost reimbursement. 252.235-7001 Section 252.235-7001 Federal Acquisition Regulations.... 2354—cost reimbursement. As prescribed in 235.070-3, use the following clause: Indemnification Under 10 U.S.C. 2354—Cost Reimbursement (DEC 1991) (a) This clause provides for indemnification under 10 U.S...

  1. Security cost allocation under combined bilateral-pool market dispatch

    International Nuclear Information System (INIS)

    Abdullah, M.P.; Hassan, M.Y.; Hussin, F.

    2008-01-01

    Most electricity markets around the world are a combination of bilateral and pool markets, such as NordPool and NYPOOL. In these models, market participants bid into the pool and also make bilateral contracts with each other. This paper addressed the issue of congestion management and security cost allocation in a power pool market model. The basic idea of security cost allocation is to divide the incurred security cost due to congestion relief into pool and bilateral market based on their flow contribution to the congested line. A newly proposed security cost allocation strategy of the combined bilateral-pool market was also presented along with case studies using IEEE-14 bus system that tested the proposed method. Using the proposed method, it was shown that security costs are allocated to market participants at different prices which reflect the load contribution to the security problem. This solves the problem of the uniform security cost allocation in a pure pool market system having uniform pricing, and provides a proper security signal to market participants. 11 refs., 3 tabs., 4 figs

  2. 45 CFR 1151.16 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false General prohibitions against discrimination. 1151... HANDICAP Discrimination Prohibited General § 1151.16 General prohibitions against discrimination. (a) No... the benefits of, or otherwise be subjected to discrimination under any program or activity which...

  3. Network formation under heterogeneous costs: The multiple group model

    NARCIS (Netherlands)

    Kamphorst, J.J.A.; van der Laan, G.

    2007-01-01

    It is widely recognized that the shape of networks influences both individual and aggregate behavior. This raises the question which types of networks are likely to arise. In this paper we investigate a model of network formation, where players are divided into groups and the costs of a link between

  4. Farmers' choice of cattle marketing channels under transaction cost ...

    African Journals Online (AJOL)

    The theoretical predictions of transaction cost economics were tested based on primary data collected from 230 cattle farm households in 13 communities of the Okhahlamba Local Municipality. The results of a multinomial logit regression revealed some unique insights. They showed that the probability of selling at auction ...

  5. Under Pressure: Tackling Pension and Health Care Costs

    Science.gov (United States)

    Friery, John

    2010-01-01

    Fueled by declining revenue from the housing crisis, skyrocketing energy costs, and an economy in general disarray, the public is pressuring school administrators to make broader and deeper cuts in their operating budgets. As the baby boomers retire, put their houses on the market, and downsize, one will see more downward price pressure on home…

  6. Distribution Grid Integration Costs Under High PV Penetrations Workshop |

    Science.gov (United States)

    utility business model and structure: policies and regulations, revenue requirements and investment Practices Panel 3: Future Directions in Grid Integration Cost-Benefit Analysis Determining Distribution Grid into Utility Planning Notes on Future Needs All speakers were asked to include their opinions on

  7. Comparing Cost Of New Supply Chain Designs Under Uncertainty

    DEFF Research Database (Denmark)

    Wæhrens, Brian Vejrum; Kristensen, Jesper; Asmussen, Jesper Normann

    2016-01-01

    Accounting, Operational Modelling and SCM inform decision making for new SCDs. Through four embedded cases, a gap is found between the practice of a global OEM and literature. Results shows complications when assessing SCDs due to limited understanding of the internal activity costs, supply chain dynamics...

  8. Children's understanding of the costs and rewards underlying rational action.

    Science.gov (United States)

    Jara-Ettinger, Julian; Gweon, Hyowon; Tenenbaum, Joshua B; Schulz, Laura E

    2015-07-01

    Humans explain and predict other agents' behavior using mental state concepts, such as beliefs and desires. Computational and developmental evidence suggest that such inferences are enabled by a principle of rational action: the expectation that agents act efficiently, within situational constraints, to achieve their goals. Here we propose that the expectation of rational action is instantiated by a naïve utility calculus sensitive to both agent-constant and agent-specific aspects of costs and rewards associated with actions. In four experiments, we show that, given an agent's choices, children (range: 5-6 year olds; N=96) can infer unobservable aspects of costs (differences in agents' competence) from information about subjective differences in rewards (differences in agents' preferences) and vice versa. Moreover, children can design informative experiments on both objects and agents to infer unobservable constraints on agents' actions. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. USE OF THE INFORMATION SYSTEM COSTS UNDER MANAGEMENT PROCESS

    Directory of Open Access Journals (Sweden)

    ECOBICI NICOLAE

    2014-12-01

    Full Text Available Decision-making takes place at all levels of the organization, taking into account both short-term outlook and long-term perspective. Plans are implemented by decisions whose purpose is materialized by formulating rational conclusions obtained as a result of financial and quantitative analysis. Thus, managerial accounting practice is deeply involved in decision making, a basic requirement of the existence of a solid managerial accounting information system cost, able to provide fundamental data.

  10. USE OF THE INFORMATION SYSTEM COSTS UNDER MANAGEMENT PROCESS

    Directory of Open Access Journals (Sweden)

    EC OBICI NICOLAE

    2014-12-01

    Full Text Available Decision-making takes place at all levels of the organization, taking into account both short-term outlook and long-term perspective. Plans are implemented by decisions whose purpose is materialized by formulating rational conclusions obtained as a result of financial and quantitative analysis. Thus, managerial accounting practice is deeply involved in decision making, a basic requirement of the existence of a solid managerial accounting information system cost, able to provide fundamental data

  11. US firms still restructuring, cutting costs under oil price uncertainty

    International Nuclear Information System (INIS)

    Koen, A.D.

    1994-01-01

    Despite more than a decade of downsizing, continuing uncertainty in oil markets is forcing US petroleum companies into another round of cutting and restructuring operations. Wellhead gas prices in the US, although still volatile, in the past 2 years have risen to levels adequate to allow profits for most producers in that sector. Higher gas reserves valuations have strengthened producers' overall balance sheets. But the slide in oil prices from the middle of fourth quarter 1993 until the recent upswing the past month has withered producers' financial performances and reserves values. With little prospect of significantly higher oil prices anytime soon, US companies feel they have little choice but to continue pressing cost cutting moves in order to sustain profits in the near term while at the same time earnings a higher return on investment in the long term. Petroleum company executives are overlooking almost no operating or investment strategy thought capable of bolstering the bottom line. Because no two US oil and gas companies are alike, each profit protection plan is a unique mix of similar solutions. Oil and gas production companies most often try to lower operating costs by vigorously selling noncore properties or business units and reducing staff. The paper discusses measures taken by oil and gas companies to lower costs

  12. Price setting under cost uncertainty and menu costs - the case of the Danish petrol market

    International Nuclear Information System (INIS)

    Stampe Christensen, M.

    1994-01-01

    This paper derives the optimal pricing policy for a firm facing menu costs and stochastic production cost. The pricing policy is a boundary pricing policy and numerical comparative static analysis shows how exogenous parameters - the drift and variance of the production cost, the discount factor and the menu costs - affect the boundaries. Analyzing daily data for the Danish petrol price illustrates that a boundary pricing policy indeed has been followed for the period 1988-1992, with occasional shifts in both the desired mark-up and more importantly in the width of the bounds. While the theoretical model can say nothing of the shifts in desired mark-up, changes in the width of the bounds are found to be consistent with the implications of the model. (au)

  13. Hospital payroll costs, productivity, and employment under prospective reimbursement.

    Science.gov (United States)

    Kidder, D; Sullivan, D

    1982-12-01

    This paper reports preliminary findings from the National Hospital Rate-Setting Study regarding the effects of State prospective reimbursement (PR) programs on measures of payroll costs and employment in hospitals. PR effects were estimated through reduced-form equations, using American Hospital Association Annual Survey data on over 2,700 hospitals from 1969 through 1978. These tests suggest that hospitals responded to PR by lowering payroll expenditures. PR also seems to have been associated with reductions in full-time equivalent staff per adjusted inpatient day. However, tests did not confirm the hypothesis that hospitals reduce payroll per full-time equivalent staff as a result of PR.

  14. Future Capacity Procurements Under Unknown Demand and Increasing Costs

    OpenAIRE

    Apostolos Burnetas; Stephen Gilbert

    2001-01-01

    In this paper we study a situation in which a broker must manage the procurement of a short-life-cycle product. As the broker observes demand for the item, she learns about the demand process. However, as is often the case in practice, it becomes either more difficult or more expensive to procure the item as the selling season advances. Thus, the broker must trade off higher procurement costs against the benefit of making ordering decisions with better information about demand. Problems of th...

  15. Cooperation under Predation Risk: Experiments on Costs and Benefits

    Science.gov (United States)

    Milinski, Manfred; Luthi, Jean H.; Eggler, Rolf; Parker, Geoffrey A.

    1997-06-01

    Two fish that cooperatively inspect a predator may have negotiated the share of the risk that each takes. A test of both the costs of predator inspection dependent on the distance from which the predator is approached and the potential benefits of cooperation was carried out strictly experimentally. We made either singletons or pairs of dead sticklebacks, Gasterosteus aculeatus, approach hungry pike, Esox lucius, by remote control according to an algorithm that mimicked natural inspection. The predation risk of both single inspectors and parallel inspecting pairs increased with closer inspection distances. A member of an inspecting pair had only about half the risk of that of a single inspector. In pairs, a companion diluted the lead fish's risk of being caught, depending on its distance behind the leader. The absolute risk difference between leader and follower was greatest for close inspection distances and decreased further away from the predator. The leader's relative risk increased with its distance ahead of the laggard. However, for a given distance between leader and laggard, the relative risks to the two fish remained similar with distance from the predator. The cost side of the inequalities that define a 'Prisoner's Dilemma' has thus been measured for this system. In a second experiment the 'attack deterrence hypothesis' of predator inspection (i.e. inspection decreases attack probability) was tested. The pike was offered a choice between two sticklebacks, one of which had carried out a predator inspection visit. There was no indication of attack deterrence through predator inspection.

  16. 48 CFR 1352.228-71 - Deductibles under required insurance coverage-cost reimbursement.

    Science.gov (United States)

    2010-10-01

    ... insurance coverage-cost reimbursement. 1352.228-71 Section 1352.228-71 Federal Acquisition Regulations... Provisions and Clauses 1352.228-71 Deductibles under required insurance coverage—cost reimbursement. As... Coverage—Cost Reimbursement (APR 2010) (a) The contractor is required to present evidence of the amount of...

  17. Rights and wrongs under the ECHR : The prohibition of abuse of rights in Article 17 of the European Convention on Human Rights

    NARCIS (Netherlands)

    de Morree, P.E.

    2016-01-01

    The prohibition of abuse of rights in Article 17 of the European Convention on Human Rights (ECHR or Convention) embodies one of the Convention’s main principles: its commitment to democracy and democratic values. The provision aims to prevent groups and individuals from successfully invoking

  18. Cost analysis of injection laryngoplasty performed under local anaesthesia versus general anaesthesia: an Australian perspective.

    Science.gov (United States)

    Chandran, D; Woods, C M; Schar, M; Ma, N; Ooi, E H; Athanasiadis, T

    2018-02-01

    To conduct a cost analysis of injection laryngoplasty performed in the operating theatre under local anaesthesia and general anaesthesia. The retrospective study included patients who had undergone injection laryngoplasty as day cases between July 2013 and March 2016. Cost data were obtained, along with patient demographics, anaesthetic details, type of injectant, American Society of Anesthesiologists score, length of stay, total operating theatre time and surgeon procedure time. A total of 20 cases (general anaesthesia = 6, local anaesthesia = 14) were included in the cost analysis. The mean total cost under general anaesthesia (AU$2865.96 ± 756.29) was significantly higher than that under local anaesthesia (AU$1731.61 ± 290.29) (p costs. Procedures performed under local anaesthesia in the operating theatre are associated with shorter operating theatre time and length of stay in the hospital, and provide significant cost savings. Further savings could be achieved if local anaesthesia procedures were performed in the office setting.

  19. 48 CFR 228.307 - Insurance under cost-reimbursement contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Insurance under cost-reimbursement contracts. 228.307 Section 228.307 Federal Acquisition Regulations System DEFENSE ACQUISITION....307 Insurance under cost-reimbursement contracts. ...

  20. 47 CFR 24.245 - Reimbursement under the Cost-Sharing Plan.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Reimbursement under the Cost-Sharing Plan. 24... 1850-1990 Mhz Band § 24.245 Reimbursement under the Cost-Sharing Plan. (a) Registration of reimbursement rights. (1) To obtain reimbursement, a PCS relocator must submit documentation of the relocation...

  1. 48 CFR 3028.307 - Insurance under cost-reimbursement contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Insurance under cost-reimbursement contracts. 3028.307 Section 3028.307 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND... Insurance 3028.307 Insurance under cost-reimbursement contracts. ...

  2. Derivative-free optimization under uncertainty applied to costly simulators

    International Nuclear Information System (INIS)

    Pauwels, Benoit

    2016-01-01

    The modeling of complex phenomena encountered in industrial issues can lead to the study of numerical simulation codes. These simulators may require extensive execution time (from hours to days), involve uncertain parameters and even be intrinsically stochastic. Importantly within the context of simulation-based optimization, the derivatives of the outputs with respect to the inputs may be inexistent, inaccessible or too costly to approximate reasonably. This thesis is organized in four chapters. The first chapter discusses the state of the art in derivative-free optimization and uncertainty modeling. The next three chapters introduce three independent - although connected - contributions to the field of derivative-free optimization in the presence of uncertainty. The second chapter addresses the emulation of costly stochastic simulation codes - stochastic in the sense simulations run with the same input parameters may lead to distinct outputs. Such was the matter of the CODESTOCH project carried out at the Summer mathematical research center on scientific computing and its applications (CEMRACS) during the summer of 2013, together with two Ph.D. students from Electricity of France (EDF) and the Atomic Energy and Alternative Energies Commission (CEA). We designed four methods to build emulators for functions whose values are probability density functions. These methods were tested on two toy functions and applied to industrial simulation codes concerned with three complex phenomena: the spatial distribution of molecules in a hydrocarbon system (IFPEN), the life cycle of large electric transformers (EDF) and the repercussions of a hypothetical accidental in a nuclear plant (CEA). Emulation was a preliminary process towards optimization in the first two cases. In the third chapter we consider the influence of inaccurate objective function evaluations on direct search - a classical derivative-free optimization method. In real settings inaccuracy may never vanish

  3. Better informing decision making with multiple outcomes cost-effectiveness analysis under uncertainty in cost-disutility space.

    Science.gov (United States)

    McCaffrey, Nikki; Agar, Meera; Harlum, Janeane; Karnon, Jonathon; Currow, David; Eckermann, Simon

    2015-01-01

    Comparing multiple, diverse outcomes with cost-effectiveness analysis (CEA) is important, yet challenging in areas like palliative care where domains are unamenable to integration with survival. Generic multi-attribute utility values exclude important domains and non-health outcomes, while partial analyses-where outcomes are considered separately, with their joint relationship under uncertainty ignored-lead to incorrect inference regarding preferred strategies. The objective of this paper is to consider whether such decision making can be better informed with alternative presentation and summary measures, extending methods previously shown to have advantages in multiple strategy comparison. Multiple outcomes CEA of a home-based palliative care model (PEACH) relative to usual care is undertaken in cost disutility (CDU) space and compared with analysis on the cost-effectiveness plane. Summary measures developed for comparing strategies across potential threshold values for multiple outcomes include: expected net loss (ENL) planes quantifying differences in expected net benefit; the ENL contour identifying preferred strategies minimising ENL and their expected value of perfect information; and cost-effectiveness acceptability planes showing probability of strategies minimising ENL. Conventional analysis suggests PEACH is cost-effective when the threshold value per additional day at home (1) exceeds $1,068 or dominated by usual care when only the proportion of home deaths is considered. In contrast, neither alternative dominate in CDU space where cost and outcomes are jointly considered, with the optimal strategy depending on threshold values. For example, PEACH minimises ENL when 1=$2,000 and 2=$2,000 (threshold value for dying at home), with a 51.6% chance of PEACH being cost-effective. Comparison in CDU space and associated summary measures have distinct advantages to multiple domain comparisons, aiding transparent and robust joint comparison of costs and multiple

  4. Better Informing Decision Making with Multiple Outcomes Cost-Effectiveness Analysis under Uncertainty in Cost-Disutility Space

    Science.gov (United States)

    McCaffrey, Nikki; Agar, Meera; Harlum, Janeane; Karnon, Jonathon; Currow, David; Eckermann, Simon

    2015-01-01

    Introduction Comparing multiple, diverse outcomes with cost-effectiveness analysis (CEA) is important, yet challenging in areas like palliative care where domains are unamenable to integration with survival. Generic multi-attribute utility values exclude important domains and non-health outcomes, while partial analyses—where outcomes are considered separately, with their joint relationship under uncertainty ignored—lead to incorrect inference regarding preferred strategies. Objective The objective of this paper is to consider whether such decision making can be better informed with alternative presentation and summary measures, extending methods previously shown to have advantages in multiple strategy comparison. Methods Multiple outcomes CEA of a home-based palliative care model (PEACH) relative to usual care is undertaken in cost disutility (CDU) space and compared with analysis on the cost-effectiveness plane. Summary measures developed for comparing strategies across potential threshold values for multiple outcomes include: expected net loss (ENL) planes quantifying differences in expected net benefit; the ENL contour identifying preferred strategies minimising ENL and their expected value of perfect information; and cost-effectiveness acceptability planes showing probability of strategies minimising ENL. Results Conventional analysis suggests PEACH is cost-effective when the threshold value per additional day at home ( 1) exceeds $1,068 or dominated by usual care when only the proportion of home deaths is considered. In contrast, neither alternative dominate in CDU space where cost and outcomes are jointly considered, with the optimal strategy depending on threshold values. For example, PEACH minimises ENL when 1=$2,000 and 2=$2,000 (threshold value for dying at home), with a 51.6% chance of PEACH being cost-effective. Conclusion Comparison in CDU space and associated summary measures have distinct advantages to multiple domain comparisons, aiding

  5. A model for the inverse 1-median problem on trees under uncertain costs

    Directory of Open Access Journals (Sweden)

    Kien Trung Nguyen

    2016-01-01

    Full Text Available We consider the problem of justifying vertex weights of a tree under uncertain costs so that a prespecified vertex become optimal and the total cost should be optimal in the uncertainty scenario. We propose a model which delivers the information about the optimal cost which respect to each confidence level \\(\\alpha \\in [0,1]\\. To obtain this goal, we first define an uncertain variable with respect to the minimum cost in each confidence level. If all costs are independently linear distributed, we present the inverse distribution function of this uncertain variable in \\(O(n^{2}\\log n\\ time, where \\(n\\ is the number of vertices in the tree.

  6. Carbon Emission Reduction with Capital Constraint under Greening Financing and Cost Sharing Contract.

    Science.gov (United States)

    Qin, Juanjuan; Zhao, Yuhui; Xia, Liangjie

    2018-04-13

    Motivated by the industrial practices, this work explores the carbon emission reductions for the manufacturer, while taking into account the capital constraint and the cap-and-trade regulation. To alleviate the capital constraint, two contracts are analyzed: greening financing and cost sharing. We use the Stackelberg game to model four cases as follows: (1) in Case A1, the manufacturer has no greening financing and no cost sharing; (2) in Case A2, the manufacturer has greening financing, but no cost sharing; (3) in Case B1, the manufacturer has no greening financing but has cost sharing; and, (4) in Case B2, the manufacturer has greening financing and cost sharing. Then, using the backward induction method, we derive and compare the equilibrium decisions and profits of the participants in the four cases. We find that the interest rate of green finance does not always negatively affect the carbon emission reduction of the manufacturer. Meanwhile, the cost sharing from the retailer does not always positively affect the carbon emission reduction of the manufacturer. When the cost sharing is low, both of the participants' profits in Case B1 (under no greening finance) are not less than that in Case B2 (under greening finance). When the cost sharing is high, both of the participants' profits in Case B1 (under no greening finance) are less than that in Case B2 (under greening finance).

  7. Modelling the Cost Performance of a Given Logistics Network Operating Under Regular and Irregular Conditions

    NARCIS (Netherlands)

    Janic, M.

    2009-01-01

    This paper develops an analytical model for the assessment of the cost performance of a given logistics network operating under regular and irregular (disruptive) conditions. In addition, the paper aims to carry out a sensitivity analysis of this cost with respect to changes of the most influencing

  8. 48 CFR 28.307 - Insurance under cost-reimbursement contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Insurance under cost-reimbursement contracts. 28.307 Section 28.307 Federal Acquisition Regulations System FEDERAL ACQUISITION...-reimbursement contracts. Cost-reimbursement contracts (and subcontracts, if the terms of the prime contract are...

  9. Carbon Emission Reduction with Capital Constraint under Greening Financing and Cost Sharing Contract

    Science.gov (United States)

    Qin, Juanjuan; Zhao, Yuhui; Xia, Liangjie

    2018-01-01

    Motivated by the industrial practices, this work explores the carbon emission reductions for the manufacturer, while taking into account the capital constraint and the cap-and-trade regulation. To alleviate the capital constraint, two contracts are analyzed: greening financing and cost sharing. We use the Stackelberg game to model four cases as follows: (1) in Case A1, the manufacturer has no greening financing and no cost sharing; (2) in Case A2, the manufacturer has greening financing, but no cost sharing; (3) in Case B1, the manufacturer has no greening financing but has cost sharing; and, (4) in Case B2, the manufacturer has greening financing and cost sharing. Then, using the backward induction method, we derive and compare the equilibrium decisions and profits of the participants in the four cases. We find that the interest rate of green finance does not always negatively affect the carbon emission reduction of the manufacturer. Meanwhile, the cost sharing from the retailer does not always positively affect the carbon emission reduction of the manufacturer. When the cost sharing is low, both of the participants’ profits in Case B1 (under no greening finance) are not less than that in Case B2 (under greening finance). When the cost sharing is high, both of the participants’ profits in Case B1 (under no greening finance) are less than that in Case B2 (under greening finance). PMID:29652859

  10. 48 CFR 428.307 - Insurance under cost-reimbursement contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Insurance under cost-reimbursement contracts. 428.307 Section 428.307 Federal Acquisition Regulations System DEPARTMENT OF...-reimbursement contracts. ...

  11. 48 CFR 1028.307 - Insurance under cost-reimbursement contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Insurance under cost-reimbursement contracts. 1028.307 Section 1028.307 Federal Acquisition Regulations System DEPARTMENT OF THE...-reimbursement contracts. ...

  12. Report: Passaic Valley Sewerage Commissioners – Unallowable Costs Claimed Under EPA Grant XP98237601

    Science.gov (United States)

    Report #08-2-0226, August 6, 2008. The grantee claimed $2,385,634 for pre-award costs under Grant XP98237601 that were incurred prior to the grant award and thus were unallowable under the grant administrative conditions and OMB Circular A-87.

  13. 42 CFR 412.405 - Preadmission services as inpatient operating costs under the inpatient psychiatric facility...

    Science.gov (United States)

    2010-10-01

    ... under the inpatient psychiatric facility prospective payment system. 412.405 Section 412.405 Public... Services of Inpatient Psychiatric Facilities § 412.405 Preadmission services as inpatient operating costs under the inpatient psychiatric facility prospective payment system. The prospective payment system...

  14. A cost effective degradation-based maintenance strategy under imperfect repair

    International Nuclear Information System (INIS)

    Wu, Fan; Niknam, Seyed A.; Kobza, John E.

    2015-01-01

    An optimization model is developed to minimize the total cost of imperfect degradation-based maintenance by determining an optimal interval of condition monitoring and the degradation level after imperfect preventive repairs. The decision model is based on a novel cost model that considers functional relationship between the expected degradation reduction and the cost of preventive repairs. The decision model is applied to simulated vibration signals with a variety of specifications of cost values and degradation model parameters. This study has initiated a new area for the research of cost effective maintenance strategies. The results clearly indicate the significance of the proposed model and the decision variables under the objective of minimal cost. For instance, the results indicate direct relationship between the optimal length of monitoring interval and the monitoring cost. However, longer monitoring interval increases the risk of failure, and therefore, more degradation reduction is needed. By increasing the slope of cumulative degradation, the cost effective strategy advocates taking more frequent monitoring. The optimal degradation level after each preventive repair is not so sensitive to the change in the degradation slope due to the uncertainty associated with degradation patterns. - Highlights: • Discuss the relationship of degradation reduction and maintenance cost. • Determine the optimal interval of condition monitoring with minimal cost. • Identify the optimal degradation level after imperfect preventive repairs. • Discuss the effects of change in the slope of cumulative degradation.

  15. 48 CFR 1428.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 1428.311 Section 1428.311... under cost-reimbursement contracts. ...

  16. Analysis of drug prohibition and estimation of budgetary implications of marijuana legalization

    OpenAIRE

    Flegr, Jan

    2009-01-01

    This paper examines the impact of drug prohibition on society. It analyzes starting-points and aims of prohibition and shows, how prohibition attempts to achieve its goals. Furthermore, it explores social costs of prohibition, mainly the impact on potencial health risks of drug use and property and violent crimes. Then it presents main reasons of failure to achieve its goals. Furthemore, this paper estimates probable budgetary implications of marijuana legalization. This estimate is based on ...

  17. 16 CFR 1608.6 - Reference to guaranty by Government prohibited.

    Science.gov (United States)

    2010-01-01

    ... prohibited. 1608.6 Section 1608.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS... guaranty by Government prohibited. No representation nor suggestion shall be made in advertising or... conforms to a flammability standard in effect under the act. ...

  18. Estimation of Finite Population Mean in Multivariate Stratified Sampling under Cost Function Using Goal Programming

    Directory of Open Access Journals (Sweden)

    Atta Ullah

    2014-01-01

    Full Text Available In practical utilization of stratified random sampling scheme, the investigator meets a problem to select a sample that maximizes the precision of a finite population mean under cost constraint. An allocation of sample size becomes complicated when more than one characteristic is observed from each selected unit in a sample. In many real life situations, a linear cost function of a sample size nh is not a good approximation to actual cost of sample survey when traveling cost between selected units in a stratum is significant. In this paper, sample allocation problem in multivariate stratified random sampling with proposed cost function is formulated in integer nonlinear multiobjective mathematical programming. A solution procedure is proposed using extended lexicographic goal programming approach. A numerical example is presented to illustrate the computational details and to compare the efficiency of proposed compromise allocation.

  19. Asian Option Pricing with Monotonous Transaction Costs under Fractional Brownian Motion

    Directory of Open Access Journals (Sweden)

    Di Pan

    2013-01-01

    Full Text Available Geometric-average Asian option pricing model with monotonous transaction cost rate under fractional Brownian motion was established. The method of partial differential equations was used to solve this model and the analytical expressions of the Asian option value were obtained. The numerical experiments show that Hurst exponent of the fractional Brownian motion and transaction cost rate have a significant impact on the option value.

  20. A multiple ship routing and speed optimization problem under time, cost and environmental objectives

    DEFF Research Database (Denmark)

    Wen, M.; Pacino, Dario; Kontovas, C.A.

    2017-01-01

    The purpose of this paper is to investigate a multiple ship routing and speed optimization problem under time, cost and environmental objectives. A branch and price algorithm as well as a constraint programming model are developed that consider (a) fuel consumption as a function of payload, (b......) fuel price as an explicit input, (c) freight rate as an input, and (d) in-transit cargo inventory costs. The alternative objective functions are minimum total trip duration, minimum total cost and minimum emissions. Computational experience with the algorithm is reported on a variety of scenarios....

  1. Costs and trade-offs of grazer-induced defenses in Scenedesmus under deficient resource

    Science.gov (United States)

    Zhu, Xuexia; Wang, Jun; Chen, Qinwen; Chen, Ge; Huang, Yuan; Yang, Zhou

    2016-01-01

    The green alga Scenedesmus obliquus can form inducible defensive morphs under grazing threat. Costs and trade-offs of inducible defense are expected to accompany the benefits of defensive morphs, but are hard to detect under nutrient-sufficient experimental conditions. To test the existence of costs associated with inducible defense, we cultured S. obliquus along resource availability gradients in the presence or absence of infochemical cues from Daphnia, and measured the strength of defensive colony formation and fitness characters. Under the lowest phosphorous concentration, the expression of inducible defensive colony resulted in decreased growth rate, which provides direct evidence for physiological costs. Along the gradient reduction of phosphorous concentration or light intensity, inducible defense in S. obliquus showed a decreasing trend. However, the photosynthetic efficiency of S. obliquus was barely affected by its defense responses, suggesting that the negative correlations between resource availability and colony formation of this alga may be due to resource-based trade-offs in the allocation of limited resources. Thus, our results indicated that expression of inducible defense of S. obliquus was impaired under insufficient phosphorus or light. Furthermore, under severe phosphate deficiency, obvious physiological costs of inducible defense could be detected even though defensive colony formation also decreased significantly. PMID:26932369

  2. Feasibility of U.S. renewable portfolio standards under cost caps and case study for Illinois

    International Nuclear Information System (INIS)

    Johnson, Sean D.; Moyer, Elisabeth J.

    2012-01-01

    Recently enacted state renewable portfolio standards (RPSs) collectively require that U.S. electricity generation by non-hydro renewables more than double by 2025. These goals are not certain to be met, however, because many RPSs apply cost caps that alter requirements if costs exceed targets. We analyze here the 2008 Illinois RPS, which is fairly typical, and find that at current electricity prices, complete implementation will require significant decreases in renewables costs even given the continuation of federal renewables subsidies. Full implementation is possible but not assured. The statutory design raises additional concerns about unintended potential consequences. The fact that windpower and solar carveouts fall under a single cost cap means that in failure mode, a less cost-effective technology can curtail deployment of a more cost-effective one. Adjacent-state provisions mean the bulk of the RPS can be met by existing wind facilities, and that new wind builds will likely occur in Iowa. The Illinois RPS, like that of many other states, appears to combine objectives inherently in conflict: preferences for local jobs, for specific technologies, for environmental benefits, and for low costs. Revisiting the legislation may be needed to make legislative success likely and to ensure that failure modes do not compromise goals. - Highlights: ► RPSs mandate that generation by non-hydro renewables in the U.S. double by 2025. ► Implementation of many RPSs is impossible without decreases in renewable costs. ► The Illinois wind requirement can largely be met by existing Iowa windpower. ► Placing technology carveouts under one cost cap allows pernicious interactions. ► The Illinois RPS statute combines different objectives inherently in conflict.

  3. 45 CFR 1153.130 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false General prohibitions against discrimination. 1153... §§ 1153.130 General prohibitions against discrimination. (a) No qualified handicapped person shall, on the... subjected to discrimination under any program or activity conducted by the agency. (b)(1) The agency, in...

  4. 45 CFR 707.6 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false General prohibitions against discrimination. 707.6.... COMMISSION ON CIVIL RIGHTS § 707.6 General prohibitions against discrimination. (a) No qualified individual... benefits of, or otherwise be subjected to discrimination under any program or activity conducted by the...

  5. 45 CFR 606.30 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false General prohibitions against discrimination. 606... THE NATIONAL SCIENCE FOUNDATION § 606.30 General prohibitions against discrimination. (a) No qualified... benefits of, or otherwise be subjected to discrimination under any program or activity conducted by the...

  6. 49 CFR 28.130 - General prohibition against discrimination.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false General prohibition against discrimination. 28.130....130 General prohibition against discrimination. (a) No qualified individual with handicaps shall, on... subjected to discrimination under any program or activity conducted by the Department. (b)(1) The Department...

  7. 32 CFR 1699.130 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false General prohibitions against discrimination... CONDUCTED BY SELECTIVE SERVICE SYSTEM § 1699.130 General prohibitions against discrimination. (a) No... the benefits of, or otherwise be subjected to discrimination under any program or activity conducted...

  8. 49 CFR 28.149 - Program accessibility: Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Program accessibility: Discrimination prohibited... § 28.149 Program accessibility: Discrimination prohibited. Except as otherwise provided in § 28.150, no... otherwise be subjected to discrimination under any program or activity conducted by the Department. ...

  9. 32 CFR 1699.149 - Program accessibility: discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Program accessibility: discrimination prohibited... CONDUCTED BY SELECTIVE SERVICE SYSTEM § 1699.149 Program accessibility: discrimination prohibited. Except as... participation in, or otherwise be subject to discrimination under any program or activity conducted by the...

  10. 19 CFR 12.101 - Seizure of prohibited switchblade knives.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Seizure of prohibited switchblade knives. 12.101...; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Switchblade Knives § 12.101 Seizure of prohibited... accordance with § 12.100(a) shall be seized under 19 U.S.C. 1595a(c). (b) Notice of seizure. Notice of...

  11. Locally optimal control under unknown dynamics with learnt cost function: application to industrial robot positioning

    Science.gov (United States)

    Guérin, Joris; Gibaru, Olivier; Thiery, Stéphane; Nyiri, Eric

    2017-01-01

    Recent methods of Reinforcement Learning have enabled to solve difficult, high dimensional, robotic tasks under unknown dynamics using iterative Linear Quadratic Gaussian control theory. These algorithms are based on building a local time-varying linear model of the dynamics from data gathered through interaction with the environment. In such tasks, the cost function is often expressed directly in terms of the state and control variables so that it can be locally quadratized to run the algorithm. If the cost is expressed in terms of other variables, a model is required to compute the cost function from the variables manipulated. We propose a method to learn the cost function directly from the data, in the same way as for the dynamics. This way, the cost function can be defined in terms of any measurable quantity and thus can be chosen more appropriately for the task to be carried out. With our method, any sensor information can be used to design the cost function. We demonstrate the efficiency of this method through simulating, with the V-REP software, the learning of a Cartesian positioning task on several industrial robots with different characteristics. The robots are controlled in joint space and no model is provided a priori. Our results are compared with another model free technique, consisting in writing the cost function as a state variable.

  12. Cost and CO2 aspects of future vehicle options in Europe under new energy policy scenarios

    International Nuclear Information System (INIS)

    Thiel, Christian; Perujo, Adolfo; Mercier, Arnaud

    2010-01-01

    New electrified vehicle concepts are about to enter the market in Europe. The expected gains in environmental performance for these new vehicle types are associated with higher technology costs. In parallel, the fuel efficiency of internal combustion engine vehicles and hybrids is continuously improved, which in turn advances their environmental performance but also leads to additional technology costs versus today's vehicles. The present study compares the well-to-wheel CO 2 emissions, costs and CO 2 abatement costs of generic European cars, including a gasoline vehicle, diesel vehicle, gasoline hybrid, diesel hybrid, plug in hybrid and battery electric vehicle. The predictive comparison is done for the snapshots 2010, 2020 and 2030 under a new energy policy scenario for Europe. The results of the study show clearly that the electrification of vehicles offer significant possibilities to reduce specific CO 2 emissions in road transport, when supported by adequate policies to decarbonise the electricity generation. Additional technology costs for electrified vehicle types are an issue in the beginning, but can go down to enable payback periods of less than 5 years and very competitive CO 2 abatement costs, provided that market barriers can be overcome through targeted policy support that mainly addresses their initial cost penalty. (author)

  13. Soil fertility erosion and the associated cost of NPK removed under ...

    African Journals Online (AJOL)

    Soil fertility erosion and the associated cost of NPK removed under different soil and ... to study the effect of different tillage practices and mulching rates on fertility ... hand plough-harrow-plant and plough-plant tillage, respectively (1 US Dollar ...

  14. 24 CFR 232.625 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE FOR NURSING HOMES, INTERMEDIATE CARE FACILITIES, BOARD AND CARE HOMES, AND ASSISTED... Fire Safety Equipment Special Requirements § 232.625 Discrimination prohibited. Any contract or...

  15. 22 CFR 217.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discrimination prohibited. 217.4 Section 217.4... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 217.4 Discrimination... participation in, be denied the benefits of, or otherwise be subjected to discrimination under any program or...

  16. 22 CFR 142.11 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discrimination prohibited. 142.11 Section 142... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Employment Practices § 142.11 Discrimination... discrimination in employment under any program or activity receiving Federal financial assistance. (2) A...

  17. 22 CFR 142.15 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discrimination prohibited. 142.15 Section 142... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Accessibility § 142.15 Discrimination... be subjected to discrimination under any program or activity to which the part applies. ...

  18. 28 CFR 42.503 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Discrimination prohibited. 42.503 Section...-Implementation of Section 504 of the Rehabilitation Act of 1973 General Provisions § 42.503 Discrimination... from participation in, be denied the benefits of, or otherwise be subjected to discrimination under any...

  19. 18 CFR 1307.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Discrimination... NONDISCRIMINATION WITH RESPECT TO HANDICAP § 1307.4 Discrimination prohibited. (a) General. No qualified handicapped... otherwise be subjected to discrimination under any program or activity to which this part applies. (b...

  20. 10 CFR 1040.13 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Discrimination prohibited. 1040.13 Section 1040.13 Energy..., as Amended; and Section 401 of the Energy Reorganization Act of 1974 § 1040.13 Discrimination... benefits of, or be otherwise subjected to discrimination under any program to which this subpart applies...

  1. 22 CFR 142.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discrimination prohibited. 142.4 Section 142.4... OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 142.4 Discrimination... participation in, be denied the benefits of, or otherwise be subjected to discrimination under any program or...

  2. Lookback Option Pricing with Fixed Proportional Transaction Costs under Fractional Brownian Motion.

    Science.gov (United States)

    Sun, Jiao-Jiao; Zhou, Shengwu; Zhang, Yan; Han, Miao; Wang, Fei

    2014-01-01

    The pricing problem of lookback option with a fixed proportion of transaction costs is investigated when the underlying asset price follows a fractional Brownian motion process. Firstly, using Leland's hedging method a partial differential equation satisfied by the value of the lookback option is derived. Then we obtain its numerical solution by constructing a Crank-Nicolson format. Finally, the effectiveness of the proposed form is verified through a numerical example. Meanwhile, the impact of transaction cost rate and volatility on lookback option value is discussed.

  3. Optimal decoding and information transmission in Hodgkin-Huxley neurons under metabolic cost constraints.

    Science.gov (United States)

    Kostal, Lubomir; Kobayashi, Ryota

    2015-10-01

    Information theory quantifies the ultimate limits on reliable information transfer by means of the channel capacity. However, the channel capacity is known to be an asymptotic quantity, assuming unlimited metabolic cost and computational power. We investigate a single-compartment Hodgkin-Huxley type neuronal model under the spike-rate coding scheme and address how the metabolic cost and the decoding complexity affects the optimal information transmission. We find that the sub-threshold stimulation regime, although attaining the smallest capacity, allows for the most efficient balance between the information transmission and the metabolic cost. Furthermore, we determine post-synaptic firing rate histograms that are optimal from the information-theoretic point of view, which enables the comparison of our results with experimental data. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  4. Economic Dispatch for Operating Cost Minimization under Real Time Pricing in Droop Controlled DC Microgrid

    DEFF Research Database (Denmark)

    Li, Chendan; Federico, de Bosio; Chen, Fang

    2017-01-01

    In this paper, an economic dispatch problem for total operation cost minimization in DC microgrids is formulated. An operating cost is associated with each generator in the microgrid, including the utility grid, combining the cost-efficiency of the system with demand response requirements...... achieving higher control accuracy and faster response. The optimization problem is solved in a heuristic method. In order to test the proposed algorithm, a six-bus droop-controlled DC microgrid is used in the case studies. Simulation results show that under variable renewable energy generation, load...... of the utility. The power flow model is included in the optimization problem, thus the transmission losses can be considered for generation dispatch. By considering the primary (local) control of the grid-forming converters of a microgrid, optimal parameters can be directly applied to this control level, thus...

  5. Demand of Insurance under the Cost-of-Capital Premium Calculation Principle

    Directory of Open Access Journals (Sweden)

    Michael Merz

    2014-06-01

    Full Text Available We study the optimal insurance design problem. This is a risk sharing problem between an insured and an insurer. The main novelty in this paper is that we study this optimization problem under a risk-adjusted premium calculation principle for the insurance cover. This risk-adjusted premium calculation principle uses the cost-of-capital approach as it is suggested (and used by the regulator and the insurance industry.

  6. Prostitution, disability and prohibition

    DEFF Research Database (Denmark)

    Thomsen, Frej Klem

    2015-01-01

    Criminalisation of prostitution, and minority rights for disabled persons, are important contemporary political issues. The article examines their intersection by analysing the conditions and arguments for making a legal exception for disabled persons to a general prohibition against purchasing...... sexual services. It explores the badness of prostitution, focusing on and discussing the argument that prostitution harms prostitutes, considers forms of regulation and the arguments for and against with emphasis on a liberty-based objection to prohibition, and finally presents and analyses three...... arguments for a legal exception, based on sexual rights, beneficence, and luck egalitarianism, respectively. It concludes that although the general case for and against criminalisation is complicated there is a good case for a legal exception....

  7. Costs of certified emission reductions under the Clean Development Mechanism of the Kyoto Protocol

    International Nuclear Information System (INIS)

    Rahman, Shaikh M.; Kirkman, Grant A.

    2015-01-01

    This paper examines the cost structure of certified emission reductions (CERs) through various types of projects under the Clean Development Mechanism (CDM) of the Kyoto Protocol. Using the CDM project data, the costs of CERs and their variation across technology and over time and space are estimated by applying alternative functional forms and specifications. Results show that the average cost of CERs decreases with the project scale and duration, scale and duration effects significantly vary across project types, and there is an upward trend in costs. The results also show that the distribution of the projects in the CDM portfolio or a given location does not strictly follow the relative cost structure, nor does the distribution of the CDM projects in different host countries follow the principle of comparative advantage. More than 84% of the CDM portfolio consists of various energy projects with substantially higher costs of CERs than afforestation and reforestation, industrial and landfill gas reduction, and methane avoidance projects, which are only 12% of all projects. While per unit cost of abatement plays an important role in the bottom-up and top-down models to evaluate emission reduction potential and analyze policy alternatives, the findings contradict the presumption of such models that project investors seek out low-cost opportunities. At the aggregate level, the cost of CER by the projects in Asia and Europe is similar but higher than those hosted in Africa, Americas, and Oceania. Yet more than 83% of the projects in the CDM portfolio are located in Asia; more than 69% of the projects are in China and India alone. China appears to have a comparative advantage (i.e., lowest opportunity cost) in energy efficiency projects, while India has a comparative advantage in hydro power projects and Brazil has a comparative advantage in wind power projects. In contrast, energy efficiency category accounts for only 8% of the CDM projects in China, hydro power

  8. Paradoxical consequences of prohibitions

    OpenAIRE

    Sheikh, Sana; Janoff-Bulman, Ronnie

    2013-01-01

    Explanations based in attribution theory claim that strong external controls such as parental restrictiveness and punishment undermine moral internalization. In contrast, three studies provide evidence that parental punishment does socialize morality, but of a particular sort: a morality focused on prohibitions (i.e., proscriptive orientation), rather than positive obligations (i.e., prescriptive orientation). Study 1 found young adults’ accounts of parental restrictiveness and punishment act...

  9. Paradoxical consequences of prohibitions.

    Science.gov (United States)

    Sheikh, Sana; Janoff-Bulman, Ronnie

    2013-08-01

    Explanations based in attribution theory claim that strong external controls such as parental restrictiveness and punishment undermine moral internalization. In contrast, 3 studies provide evidence that parental punishment does socialize morality, but of a particular sort: a morality focused on prohibitions (i.e., proscriptive orientation) rather than positive obligations (i.e., prescriptive orientation). Study 1 found young adults' accounts of parental restrictiveness and punishment activated their sensitivity to prohibitions and predicted a proscriptive orientation. Consistent with the greater potency of temptations for proscriptively oriented children, as well as past research linking shame to proscriptive morality, Study 2 found that restrictive parenting was also associated with greater suppression of temptations. Finally, Studies 3A and 3B found that suppressing these immoral thoughts is paradoxically harder for those with strong proscriptive orientations; more specifically, priming a proscriptive (versus prescriptive) orientation and inducing mental suppression of "immoral" thoughts led to the most ego depletion for those with restrictive parents. Overall, individuals who had restrictive parents had the lowest self-regulatory ability to resist their "immoral" temptations after prohibitions were activated. In contrast to common attributional explanations, these studies suggest that harsh external control by parents does not undercut moral socialization but rather undermines individuals' ability to resist temptation.

  10. Non-linear increase of respiratory diseases and their costs under severe air pollution.

    Science.gov (United States)

    Shen, Ying; Wu, Yiyun; Chen, Guangdi; Van Grinsven, Hans J M; Wang, Xiaofeng; Gu, Baojing; Lou, Xiaoming

    2017-05-01

    China is experiencing severe and persistent air pollution, with concentrations of fine particulate matters (PM 2.5 ) reaching unprecedentedly high levels in many cities. Quantifying the detrimental effects on health and their costs derived from high PM 2.5 levels is crucial because of the unsolved challenges to mitigate air pollution in the following decades. Using the daily monitoring data on PM 2.5 concentrations and clinic visits, we found a non-linear increase of respiratory diseases, but not for other diseases (e.g., digestive diseases) under severe air pollution. We found an increase of respiratory diseases by 1% for each 10 μg m -3 increase in PM 2.5 when the annual average daily PM 2.5 concentration was less than 50 μg m -3 ; while this ratio was doubled (around 2%) with the daily PM 2.5 concentration larger than 50 μg m -3 . Under severe air pollution (PM 2.5 concentration >150 μg m -3 ), the respiratory diseases increased by over 50% compared to that in clean days. Children are more sensitive to the severe air pollution. The increase of clinic visits, especially for adults, was observed mainly in bigger (>500 beds) hospitals. Re-allocating medical resources (e.g., doctors) from big hospitals to community hospitals can benefit the respiratory patients due to air pollution. The total medical cost of clinic visits of respiratory diseases derived from PM 2.5 pollution was estimated at 17.2-57.0 billion Yuan in 2014 in China, accounting for 0.5-1.6% of national total health expenditure. Because these medical costs only represent a small part of total health cost derived from air pollution, the reduction of associated health costs would be an important co-benefit of implementation of air pollution preventive strategies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. 30 CFR 229.109 - Reimbursement for costs incurred by a State under the delegation of authority.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Reimbursement for costs incurred by a State... Administration of Delegations § 229.109 Reimbursement for costs incurred by a State under the delegation of..., on a quarterly basis, a summary of costs incurred for which the State is seeking reimbursement. Only...

  12. 20 CFR 1002.310 - How are fees and court costs charged or taxed in an action under USERRA?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false How are fees and court costs charged or taxed... Enforcement of Rights and Benefits Against A State Or Private Employer § 1002.310 How are fees and court costs charged or taxed in an action under USERRA? No fees or court costs may be charged or taxed against an...

  13. Collaborative testing for key-term definitions under representative conditions: Efficiency costs and no learning benefits.

    Science.gov (United States)

    Wissman, Kathryn T; Rawson, Katherine A

    2018-01-01

    Students are expected to learn key-term definitions across many different grade levels and academic disciplines. Thus, investigating ways to promote understanding of key-term definitions is of critical importance for applied purposes. A recent survey showed that learners report engaging in collaborative practice testing when learning key-term definitions, with outcomes also shedding light on the way in which learners report engaging in collaborative testing in real-world contexts (Wissman & Rawson, 2016, Memory, 24, 223-239). However, no research has directly explored the effectiveness of engaging in collaborative testing under representative conditions. Accordingly, the current research evaluates the costs (with respect to efficiency) and the benefits (with respect to learning) of collaborative testing for key-term definitions under representative conditions. In three experiments (ns = 94, 74, 95), learners individually studied key-term definitions and then completed retrieval practice, which occurred either individually or collaboratively (in dyads). Two days later, all learners completed a final individual test. Results from Experiments 1-2 showed a cost (with respect to efficiency) and no benefit (with respect to learning) of engaging in collaborative testing for key-term definitions. Experiment 3 evaluated a theoretical explanation for why collaborative benefits do not emerge under representative conditions. Collectively, outcomes indicate that collaborative testing versus individual testing is less effective and less efficient when learning key-term definitions under representative conditions.

  14. 45 CFR 1351.15 - What costs are supportable under a Runaway and Homeless Youth Program grant?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What costs are supportable under a Runaway and... FOR CHILDREN, YOUTH AND FAMILIES, FAMILY AND YOUTH SERVICES BUREAU RUNAWAY AND HOMELESS YOUTH PROGRAM Runaway and Homeless Youth Program Grant § 1351.15 What costs are supportable under a Runaway and Homeless...

  15. 45 CFR 1351.16 - What costs are not allowable under a Runaway and Homeless Youth Program grant?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What costs are not allowable under a Runaway and... FOR CHILDREN, YOUTH AND FAMILIES, FAMILY AND YOUTH SERVICES BUREAU RUNAWAY AND HOMELESS YOUTH PROGRAM Runaway and Homeless Youth Program Grant § 1351.16 What costs are not allowable under a Runaway and...

  16. 48 CFR 228.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 228.311 Section 228.311 Federal... liability insurance under cost-reimbursement contracts. ...

  17. 48 CFR 1828.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 1828.311 Section 1828.311... insurance under cost-reimbursement contracts. ...

  18. 48 CFR 3028.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 3028.311 Section 3028.311... contract clause on liability insurance under cost-reimbursement contracts. ...

  19. 48 CFR 328.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 328.311 Section 328.311 Federal... Insurance 328.311 Solicitation provision and contract clause on liability insurance under cost-reimbursement...

  20. Decreasing the cost of ground grid installations under difficult environmental conditions

    International Nuclear Information System (INIS)

    Miranda, E.P.

    1992-01-01

    The purpose of a ground grid is to provide a means to carry and dissipate electrical currents into ground under normal and fault conditions. In some cases, especially in dry rock terrain, the soil resistivity can be very high, making it difficult and very expensive to install an acceptable ground grid. Usually a soil resistivity above 200 ohm-meter is considered high. This paper discusses and provides design calculations for a successful ground grid installation in a distribution substation located in one of the worst soil conditions encountered in the industry; a very rocky terrain where the resistivity is 1800 ohm-m. It is a practical application of the theories presented in ANSI/IEEE Std. 80-1986. The design application consists of bare copper combined with conventional and a new type of ground rod. The installation cost for this application was much less than the cost associated with that of a conventional installation

  1. Cost of heat from a seasonal source

    Science.gov (United States)

    Reilly, R. W.; Brown, D. R.; Huber, H. D.

    Results are reported of an investigation to estimate the cost of aquifer thermal energy storage (ATES) from a seasonal heat source. The cost of supplying energy (hot water) from an ATES system is estimated. Three types of loads are investigated: point demands, residential developments, and a multidistrict city. Several technical and economic factors are found to control the economic performance of an ATES system. Costs are found to be prohibitive for systems of small size, long transmission distances, and employing expensive purchased thermal energy. ATES is found to be cost-competitive with oil-fired and electric hot water delivery systems under a broad range of potential situations.

  2. Counting Costs under Severe Financial Constraints: A Cost-of-Illness Analysis of Spondyloarthropathies in a Tertiary Hospital in Greece.

    Science.gov (United States)

    Tsifetaki, Niki; Migkos, Michail P; Papagoras, Charalampos; Voulgari, Paraskevi V; Athanasakis, Kostas; Drosos, Alexandros A

    2015-06-01

    To investigate the total annual direct cost of patients with spondyloarthritis (SpA) in Greece. Retrospective study with 156 patients diagnosed and followed up in the rheumatology clinic of the University Hospital of Ioannina. Sixty-four had ankylosing spondylitis (AS) and 92 had psoriatic arthritis (PsA). Health resource use for each patient was elicited through a retrospective chart review that documented the use of monitoring visits, medications, laboratory/diagnostic tests, and inpatient stays for the previous year from the date that the review took place. Costs were calculated from a third-party payer perspective and are reported in 2014 euros. The mean ± SD annual direct cost for the patients with SpA reached €8680 ± 6627. For the patients with PsA and AS, the cost was estimated to be €8097 ± 6802 and €9531 ± 6322, respectively. The major cost was medication, which represented 88.9%, 88.2%, and 89.3% of the mean total direct cost for SpA, AS, and PsA, respectively. The annual amount of the scheduled tests for all patients corresponded to 7.5%, and for those performed on an emergency basis, 1.1%. Further, the cost for scheduled and emergency hospitalization, as well as the cost of scheduled visits to an outpatient clinic, corresponded to 2.5% of the mean total annual direct cost for the patients with SpA. SpA carries substantial financial cost, especially in the era of new treatment options. Adequate access and treatment for patients with SpA remains a necessity, even in times of fiscal constraint. Thus, the recommendations of the international scientific organizations should be considered when administering high-cost drugs such as biological treatments.

  3. Aphid wing induction and ecological costs of alarm pheromone emission under field conditions.

    Directory of Open Access Journals (Sweden)

    Eduardo Hatano

    2010-06-01

    Full Text Available The pea aphid, Acyrthosiphon pisum Harris, (Homoptera: Aphididae releases the volatile sesquiterpene (E-beta-farnesene (EBF when attacked by a predator, triggering escape responses in the aphid colony. Recently, it was shown that this alarm pheromone also mediates the production of the winged dispersal morph under laboratory conditions. The present work tested the wing-inducing effect of EBF under field conditions. Aphid colonies were exposed to two treatments (control and EBF and tested in two different environmental conditions (field and laboratory. As in previous experiments aphids produced higher proportion of winged morphs among their offspring when exposed to EBF in the laboratory but even under field conditions the proportion of winged offspring was higher after EBF application (6.84+/-0.98% compared to the hexane control (1.54+/-0.25%. In the field, the proportion of adult aphids found on the plant at the end of the experiment was lower in the EBF treatment (58.1+/-5.5% than in the control (66.9+/-4.6%, in contrast to the climate chamber test where the numbers of adult aphids found on the plant at the end of the experiment were, in both treatments, similar to the numbers put on the plant initially. Our results show that the role of EBF in aphid wing induction is also apparent under field conditions and they may indicate a potential cost of EBF emission. They also emphasize the importance of investigating the ecological role of induced defences under field conditions.

  4. Life cycle cost optimization of biofuel supply chains under uncertainties based on interval linear programming.

    Science.gov (United States)

    Ren, Jingzheng; Dong, Liang; Sun, Lu; Goodsite, Michael Evan; Tan, Shiyu; Dong, Lichun

    2015-01-01

    The aim of this work was to develop a model for optimizing the life cycle cost of biofuel supply chain under uncertainties. Multiple agriculture zones, multiple transportation modes for the transport of grain and biofuel, multiple biofuel plants, and multiple market centers were considered in this model, and the price of the resources, the yield of grain and the market demands were regarded as interval numbers instead of constants. An interval linear programming was developed, and a method for solving interval linear programming was presented. An illustrative case was studied by the proposed model, and the results showed that the proposed model is feasible for designing biofuel supply chain under uncertainties. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. To favor survival under food shortage, the brain disables costly memory.

    Science.gov (United States)

    Plaçais, Pierre-Yves; Preat, Thomas

    2013-01-25

    The brain regulates energy homeostasis in the organism. Under resource shortage, the brain takes priority over peripheral organs for energy supply. But can the brain also down-regulate its own consumption to favor survival? We show that the brain of Drosophila specifically disables the costly formation of aversive long-term memory (LTM) upon starvation, a physiological state required for appetitive LTM formation. At the neural circuit level, the slow oscillations normally triggered in two pairs of dopaminergic neurons to enable aversive LTM formation were abolished in starved flies. Transient artificial activation of these neurons during training restored LTM formation in starved flies but at the price of a reduced survival. LTM formation is thus subject to adaptive plasticity that helps survival under food shortage.

  6. Cost-optimal power system extension under flow-based market coupling

    Energy Technology Data Exchange (ETDEWEB)

    Hagspiel, Simeon; Jaegemann, Cosima; Lindenberger, Dietmar [Koeln Univ. (Germany). Energiewirtschaftliches Inst.; Brown, Tom; Cherevatskiy, Stanislav; Troester, Eckehard [Energynautics GmbH, Langen (Germany)

    2013-05-15

    Electricity market models, implemented as dynamic programming problems, have been applied widely to identify possible pathways towards a cost-optimal and low carbon electricity system. However, the joint optimization of generation and transmission remains challenging, mainly due to the fact that different characteristics and rules apply to commercial and physical exchanges of electricity in meshed networks. This paper presents a methodology that allows to optimize power generation and transmission infrastructures jointly through an iterative approach based on power transfer distribution factors (PTDFs). As PTDFs are linear representations of the physical load flow equations, they can be implemented in a linear programming environment suitable for large scale problems. The algorithm iteratively updates PTDFs when grid infrastructures are modified due to cost-optimal extension and thus yields an optimal solution with a consistent representation of physical load flows. The method is first demonstrated on a simplified three-node model where it is found to be robust and convergent. It is then applied to the European power system in order to find its cost-optimal development under the prescription of strongly decreasing CO{sub 2} emissions until 2050.

  7. Effects of competition on the cost and quality of inpatient rehabilitation care under prospective payment.

    Science.gov (United States)

    Colla, Carrie Hoverman; Escarce, José J; Buntin, Melinda Beeuwkes; Sood, Neeraj

    2010-12-01

    To determine the effect of competition in postacute care (PAC) markets on resource intensity and outcomes of care in inpatient rehabilitation facilities (IRFs) after prospective payment was implemented. Medicare claims, Provider of Services file, Enrollment file, Area Resource file, Minimum Data Set. We created an exogenous measure of competition based on patient travel distances and used instrumental variables models to estimate the effect of competition on inpatient rehabilitation costs, length of stay, and death or institutionalization. A file was constructed linking data for Medicare patients discharged from acute care between 2002 and 2003 and admitted to an IRF with a diagnosis of hip fracture or stroke. Competition had different effects on treatment intensity and outcomes for hip fracture and stroke patients. In the treatment of hip fracture, competition increased costs and length of stay, while increasing rates of death or institutionalization. In the treatment of stroke, competition decreased costs and length of stay and produced inferior outcomes. The effects of competition in PAC markets may vary by condition. It is important to study the effects of competition by diagnostic condition and to study the effects across populations that vary in severity. Our finding that higher competition under prospective payment led to worse IRF outcomes raises concerns and calls for additional research. © Health Research and Educational Trust.

  8. Removal costs and claims under the Oil Pollution Act of 1990

    International Nuclear Information System (INIS)

    Smith, R.E.

    1993-01-01

    The Oil Pollution Act of 1990 (OPA 90), enacted on August 18, 1990, changed the nature of federal response to oil spills and substantially increased the remedies available to those damaged by oil spills. Prior to OPA 90, the authority for federal oil spill response was found in section 311 of the Federal Water Pollution Control Act (FWPCA), and the funding for federal responses was provided through a revolving fund established under section 311(k). OPA 90 modified section 311 to authorize the President to open-quotes direct and monitor all Federal, State, and private actions to remove a dischargeclose quotes of oil. OPA 90 also authorized the use of the Oil Spill Liability Trust Fund (OSLTF) for federal removal costs, among other uses, thereby significantly increasing the funding available for federal response activities. The effect of OPA 90 is evolving. There are more cases, more removal costs, and more efforts to recover those costs from responsible parties. There are provisions for compensation for claims but relatively few claims so far. It is expected that the next two years will see substantial increases in the number of claims

  9. Cost of Oil and Biomass Supply Shocks under Different Biofuel Supply Chain Configurations

    Energy Technology Data Exchange (ETDEWEB)

    Uria Martinez, Rocio [ORNL; Leiby, Paul Newsome [ORNL; Brown, Maxwell L. [National Renewable Energy Laboratory (NREL)

    2018-04-01

    This analysis estimates the cost of selected oil and biomass supply shocks for producers and consumers in the light-duty vehicle fuel market under various supply chain configurations using a mathematical programing model, BioTrans. The supply chain configurations differ by whether they include selected flexibility levers: multi-feedstock biorefineries; advanced biomass logistics; and the ability to adjust ethanol content of low-ethanol fuel blends, from E10 to E15 or E05. The simulated scenarios explore market responses to supply shocks including substitution between gasoline and ethanol, substitution between different sources of ethanol supply, biorefinery capacity additions or idling, and price adjustments. Welfare effects for the various market participants represented in BioTrans are summarized into a net shock cost measure. As oil accounts for a larger fraction of fuel by volume, its supply shocks are costlier than biomass supply shocks. Corn availability and the high cost of adding biorefinery capacity limit increases in ethanol use during gasoline price spikes. During shocks that imply sudden decreases in the price of gasoline, the renewable fuel standard (RFS) biofuel blending mandate limits the extent to which flexibility can be exercised to reduce ethanol use. The selected flexibility levers are most useful in response to cellulosic biomass supply shocks.

  10. 45 CFR 1610.3 - Prohibition.

    Science.gov (United States)

    2010-10-01

    ... OF LSC FUNDS, PROGRAM INTEGRITY § 1610.3 Prohibition. A recipient may not use non-LSC funds for any purpose prohibited by the LSC Act or for any activity prohibited by or inconsistent with Section 504...

  11. Modeling Electricity Sector Vulnerabilities and Costs Associated with Water Temperatures Under Scenarios of Climate Change

    Science.gov (United States)

    Macknick, J.; Miara, A.; Brinkman, G.; Ibanez, E.; Newmark, R. L.

    2014-12-01

    The reliability of the power sector is highly vulnerable to variability in the availability and temperature of water resources, including those that might result from potential climatic changes or from competition from other users. In the past decade, power plants throughout the United States have had to shut down or curtail generation due to a lack of available water or from elevated water temperatures. These disruptions in power plant performance can have negative impacts on energy security and can be costly to address. Analysis of water-related vulnerabilities requires modeling capabilities with high spatial and temporal resolution. This research provides an innovative approach to energy-water modeling by evaluating the costs and reliability of a power sector region under policy and climate change scenarios that affect water resource availability and temperatures. This work utilizes results from a spatially distributed river water temperature model coupled with a thermoelectric power plant model to provide inputs into an electricity production cost model that operates on a high spatial and temporal resolution. The regional transmission organization ISO-New England, which includes six New England states and over 32 Gigawatts of power capacity, is utilized as a case study. Hydrological data and power plant operations are analyzed over an eleven year period from 2000-2010 under four scenarios that include climate impacts on water resources and air temperatures as well as strict interpretations of regulations that can affect power plant operations due to elevated water temperatures. Results of these model linkages show how the power sector's reliability and economic performance can be affected by changes in water temperatures and water availability. The effective reliability and capacity value of thermal electric generators are quantified and discussed in the context of current as well as potential future water resource characteristics.

  12. 48 CFR 528.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 528.311 Section 528.311 Federal...-reimbursement contracts. ...

  13. 48 CFR 28.311 - Solicitation provision and contract clause on liability insurance under cost-reimbursement...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Solicitation provision and contract clause on liability insurance under cost-reimbursement contracts. 28.311 Section 28.311 Federal...-reimbursement contracts. ...

  14. 34 CFR 75.532 - Use of funds for religion prohibited.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Use of funds for religion prohibited. 75.532 Section 75.532 Education Office of the Secretary, Department of Education DIRECT GRANT PROGRAMS What Conditions Must Be Met by a Grantee? Allowable Costs § 75.532 Use of funds for religion prohibited. (a) No grantee...

  15. Safety Evaluations Under the Proposed US Safe Cosmetics and Personal Care Products Act of 2013 : Animal Use and Cost Estimates

    OpenAIRE

    Knight, Jean; Rovida, Costanza

    2014-01-01

    The proposed Safe Cosmetics and Personal Care Products Act of 2013 calls for a new evaluation program for cosmetic ingredients in the US, with the new assessments initially dependent on expanded animal testing. This paper considers possible testing scenarios under the proposed Act and estimates the number of test animals and cost under each scenario. It focuses on the impact for the first 10 years of testing, the period of greatest impact on animals and costs. The analysis suggests the first ...

  16. Using Microsimulation to Estimate the Future Health and Economic Costs of Salmonellosis under Climate Change in Central Queensland, Australia.

    Science.gov (United States)

    Stephen, Dimity Maree; Barnett, Adrian Gerard

    2017-12-11

    The incidence of salmonellosis, a costly foodborne disease, is rising in Australia. Salmonellosis increases during high temperatures and rainfall, and future incidence is likely to rise under climate change. Allocating funding to preventative strategies would be best informed by accurate estimates of salmonellosis costs under climate change and by knowing which population subgroups will be most affected. We used microsimulation models to estimate the health and economic costs of salmonellosis in Central Queensland under climate change between 2016 and 2036 to inform preventative strategies. We projected the entire population of Central Queensland to 2036 by simulating births, deaths, and migration, and salmonellosis and two resultant conditions, reactive arthritis and postinfectious irritable bowel syndrome. We estimated salmonellosis risks and costs under baseline conditions and under projected climate conditions for Queensland under the A1FI emissions scenario using composite projections from 6 global climate models (warm with reduced rainfall). We estimated the resulting costs based on direct medical expenditures combined with the value of lost quality-adjusted life years (QALYs) based on willingness-to-pay. Estimated costs of salmonellosis between 2016 and 2036 increased from 456.0 QALYs (95% CI: 440.3, 473.1) and AUD29,900,000 million (95% CI: AUD28,900,000, AUD31,600,000), assuming no climate change, to 485.9 QALYs (95% CI: 469.6, 503.5) and AUD31,900,000 (95% CI: AUD30,800,000, AUD33,000,000) under the climate change scenario. We applied a microsimulation approach to estimate the costs of salmonellosis and its sequelae in Queensland during 2016-2036 under baseline conditions and according to climate change projections. This novel application of microsimulation models demonstrates the models' potential utility to researchers for examining complex interactions between weather and disease to estimate future costs. https://doi.org/10.1289/EHP1370.

  17. Today's fentanyl crisis: Prohibition's Iron Law, revisited.

    Science.gov (United States)

    Beletsky, Leo; Davis, Corey S

    2017-08-01

    More than a decade in the making, America's opioid crisis has morphed from being driven by prescription drugs to one fuelled by heroin and, increasingly, fentanyl. Drawing on historical lessons of the era of National Alcohol Prohibition highlights the unintended, but predictable impact of supply-side interventions on the dynamics of illicit drug markets. Under the Iron Law of Prohibition, efforts to interrupt and suppress the illicit drug supply produce economic and logistical pressures favouring ever-more compact substitutes. This iatrogenic progression towards increasingly potent illicit drugs can be curtailed only through evidence-based harm reduction and demand reduction policies that acknowledge the structural determinants of health. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Neural Mechanisms Underlying the Cost of Task Switching: An ERP Study

    Science.gov (United States)

    Li, Ling; Wang, Meng; Zhao, Qian-Jing; Fogelson, Noa

    2012-01-01

    Background When switching from one task to a new one, reaction times are prolonged. This phenomenon is called switch cost (SC). Researchers have recently used several kinds of task-switching paradigms to uncover neural mechanisms underlying the SC. Task-set reconfiguration and passive dissipation of a previously relevant task-set have been reported to contribute to the cost of task switching. Methodology/Principal Findings An unpredictable cued task-switching paradigm was used, during which subjects were instructed to switch between a color and an orientation discrimination task. Electroencephalography (EEG) and behavioral measures were recorded in 14 subjects. Response-stimulus interval (RSI) and cue-stimulus interval (CSI) were manipulated with short and long intervals, respectively. Switch trials delayed reaction times (RTs) and increased error rates compared with repeat trials. The SC of RTs was smaller in the long CSI condition. For cue-locked waveforms, switch trials generated a larger parietal positive event-related potential (ERP), and a larger slow parietal positivity compared with repeat trials in the short and long CSI condition. Neural SC of cue-related ERP positivity was smaller in the long RSI condition. For stimulus-locked waveforms, a larger switch-related central negative ERP component was observed, and the neural SC of the ERP negativity was smaller in the long CSI. Results of standardized low resolution electromagnetic tomography (sLORETA) for both ERP positivity and negativity showed that switch trials evoked larger activation than repeat trials in dorsolateral prefrontal cortex (DLPFC) and posterior parietal cortex (PPC). Conclusions/Significance The results provide evidence that both RSI and CSI modulate the neural activities in the process of task-switching, but that these have a differential role during task-set reconfiguration and passive dissipation of a previously relevant task-set. PMID:22860090

  19. Neural mechanisms underlying the cost of task switching: an ERP study.

    Directory of Open Access Journals (Sweden)

    Ling Li

    Full Text Available BACKGROUND: When switching from one task to a new one, reaction times are prolonged. This phenomenon is called switch cost (SC. Researchers have recently used several kinds of task-switching paradigms to uncover neural mechanisms underlying the SC. Task-set reconfiguration and passive dissipation of a previously relevant task-set have been reported to contribute to the cost of task switching. METHODOLOGY/PRINCIPAL FINDINGS: An unpredictable cued task-switching paradigm was used, during which subjects were instructed to switch between a color and an orientation discrimination task. Electroencephalography (EEG and behavioral measures were recorded in 14 subjects. Response-stimulus interval (RSI and cue-stimulus interval (CSI were manipulated with short and long intervals, respectively. Switch trials delayed reaction times (RTs and increased error rates compared with repeat trials. The SC of RTs was smaller in the long CSI condition. For cue-locked waveforms, switch trials generated a larger parietal positive event-related potential (ERP, and a larger slow parietal positivity compared with repeat trials in the short and long CSI condition. Neural SC of cue-related ERP positivity was smaller in the long RSI condition. For stimulus-locked waveforms, a larger switch-related central negative ERP component was observed, and the neural SC of the ERP negativity was smaller in the long CSI. Results of standardized low resolution electromagnetic tomography (sLORETA for both ERP positivity and negativity showed that switch trials evoked larger activation than repeat trials in dorsolateral prefrontal cortex (DLPFC and posterior parietal cortex (PPC. CONCLUSIONS/SIGNIFICANCE: The results provide evidence that both RSI and CSI modulate the neural activities in the process of task-switching, but that these have a differential role during task-set reconfiguration and passive dissipation of a previously relevant task-set.

  20. 45 CFR 310.30 - Under what circumstances would FFP be suspended or disallowed in the costs of Computerized Tribal...

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Under what circumstances would FFP be suspended or... SYSTEMS AND OFFICE AUTOMATION Funding for Computerized Tribal IV-D Systems and Office Automation § 310.30 Under what circumstances would FFP be suspended or disallowed in the costs of Computerized Tribal IV-D...

  1. Analysis of the cost effectiveness of protecting indoor air from radon from the underlying structures

    International Nuclear Information System (INIS)

    Skrabalek, P.

    2017-01-01

    Exposure to radon in buildings is the largest and yet underestimated source of ionizing radiation doses of the Slovak population. The most affected are the people currently living in family houses, where the radon from the building's constructions is also exposed to radon from building background. At work the authors have shown that protecting the air of family houses and other buildings from radon pollution from underlying structures is not an economic but a political issue. They have shown that preventive protective measures must be taken in the construction of each house, whether it is a family house or another building. The cost of preventive measures for the construction of family houses, while maintaining the current trend, will amount to around 3 million Eur each year, because during that time, approximately 10,300 new buildings were built. These costs are entirely at the expense of builders, because radon protection must be part of the construction project and at present prices range from 225 to 405 Eur per building. Benefits will begin to show at the earliest 25-30 years after construction, and will reach around 12 million Eur (calculated at today's medical care prices and the current minimum wage). The projected costs of identifying occupied homes that urgently need to make remedial measures will reach about 1 million Eur / yr and cover 20,000 homes. It will be necessary to build a laboratory of alpha tremor dosimetry within Slovak legal metrology, with a capacity to process about 50,000 dosimetric kits annually. Examination of the occupied houses by this procedure will last for at least 40 years, because apart from geological and geophysical criteria, there is nothing to exclude any group of houses from the survey. According to estimates from previous surveys, about 16,700 objects need to be identified annually, which need to optimize radon concentration by technical or construction means. The remedial measures will need to be around 24.6 million Eur, of

  2. 45 CFR 1630.3 - Standards governing allowability of costs under Corporation grants or contracts.

    Science.gov (United States)

    2010-10-01

    ... services to low-income clients, allocation of indirect costs may be by a simplified allocation method... accordance with the relative benefits received. Costs may be allocated to Corporation funds either as direct... necessary to the overall operation of the recipient, although a direct relationship to any particular cost...

  3. Hardwood? Carpet? or Tile? A comparison of flooring costs under residential conditions

    Science.gov (United States)

    David G. Martens; David G. Martens

    1971-01-01

    Initial installation cost, annual maintenance cost, and total long-term cost are important in the purchase of flooring products. Before deciding on a flooring material, the prudent buyer will consider each of these in relation to his personal desires. From these evaluations, he will then be able to select the flooring material that is best suited to his individual...

  4. 20 CFR 411.582 - Can a State VR agency receive payment under the cost reimbursement payment system if a continuous...

    Science.gov (United States)

    2010-04-01

    ... the cost reimbursement payment system if a continuous 9-month period of substantial gainful activity... Systems § 411.582 Can a State VR agency receive payment under the cost reimbursement payment system if a... under the cost reimbursement payment system under subpart V of part 404 (or subpart V of part 416) of...

  5. On optimal upgrade level for used products under given cost structures

    International Nuclear Information System (INIS)

    Shafiee, Mahmood; Finkelstein, Maxim; Chukova, Stefanka

    2011-01-01

    In spite of the growing share of the second-hand market, often customers of used products encounter the following three problems: (a) they are uncertain regarding the durability and performance of these products due to lack of information on the item's past usage and maintenance history, (b) they are uncertain about the accurate pricing of warranties and the post-warranty repair costs, and (c) sometimes, right after the sale, used items may have high failure rate and could be harmful to their new owner. Due to these problems, the dealers are currently carrying out actions such as overhaul and upgrade of the used products before their release. Reliability improvement, which is closely related to the concept of warranty, for used products is a relatively new concept and has received very limited attention. This paper also develops a stochastic model which results in the derivation of the optimal expected upgrade level under given structures of the profit and failure rate functions. We provide a numerical study to illustrate our results.

  6. Electric Car Users’ Time of Charging Problem under Peak Load Pricing When Delay in Charging Time Involves Uncertain Cost

    DEFF Research Database (Denmark)

    Fetene, Gebeyehu Manie

    The problem of peak load arises when demand fluctuates over time while the pro- duction technology is not flexible (or making it flexible is economically inefficient) and/or when a product is non-storable (or storage cost is huge). Peak load is a com- mon problem in consumption of public utilities......, on the one hand, observed cost saving benefit of postponing the time of charging to off-peak lower fee of charging and, on the other hand, the cost of delay in departure time for planned trips and uncertain cost of late charging associated with likelihood occur- rence of unanticipated trip before the car...... of electricity. The electric vehicle (EV) users choice of time of charging problem under PLP is different from that of general households using energy for house appliances since there is uncertain cost to the former as- sociated with likelihood occurrence of unanticipated trips such as visiting hospital...

  7. Dynamic analysis of hybrid energy systems under flexible operation and variable renewable generation – Part II: Dynamic cost analysis

    International Nuclear Information System (INIS)

    Garcia, Humberto E.; Mohanty, Amit; Lin, Wen-Chiao; Cherry, Robert S.

    2013-01-01

    Dynamic analysis of HES (hybrid energy systems) under flexible operation and variable renewable generation is considered in this two-part communication to better understand various challenges and opportunities associated with the high system variability arising from the integration of renewable energy into the power grid. Advanced HES solutions are investigated in which multiple forms of energy commodities, such as electricity and chemical products, may be exchanged. In particular, a comparative dynamic cost analysis is conducted in this part two of the communication to determine best HES options. The cost function includes a set of metrics for computing fixed costs, such as fixed operations and maintenance and overnight capital costs, and also variable operational costs, such as cost of operational variability, variable operations and maintenance cost, and cost of environmental impact, together with revenues. Assuming natural gas, coal, and nuclear as primary heat sources, preliminary results identify the level of renewable penetration at which a given advanced HES option (e.g., a nuclear hybrid) becomes increasingly more economical than a traditional electricity-only generation solution. Conditions are also revealed under which carbon resources may be better utilized as carbon sources for chemical production rather than as combustion material for electricity generation. - Highlights: ► Dynamic analysis of HES to investigate challenges related to renewable penetration. ► Evaluation of dynamic synergies among HES constituents on system performance. ► Comparison of traditional versus advanced HES candidates. ► Dynamic cost analysis of HES candidates to investigate their economic viability. ► Identification of conditions under which an energy commodity may be best utilized

  8. Waste management and the land disposal restriction storage prohibition

    International Nuclear Information System (INIS)

    1992-05-01

    RCRA Sect. 3004(j) prohibits storage of wastes that have been prohibited from land disposal, unless that storage is for the purpose of accumulating sufficient quantities of hazardous wastes to facilitate proper recovery, treatment, or disposal. This requirement was incorporated as part of the Land Disposal Restriction (LDR) regulations. Under the LDR storage prohibition, facilities may only store restricted wastes in containers and tanks. As stated in the Third LDR rule, storage of prohibited waste is only allowed in non-land based storage units since land-based storage is a form of disposal. The EPA has recognized that generators and storers of radioactive mixed waste (RMW) may find it impossible to comply with storage prohibition in cases where no available treatment capacity exists. Additionally, under the current regulatory interpretation, there is no provision that would allow for storage of wastes for which treatment capacity and capability are not available, even where capacity is legitimately being developed. Under the LDR program, restricted wastes that are disposed of, or placed into storage before an LDR effective date, are not subject to the LDR requirements. However, if such wastes are removed from a storage or disposal site after the effective date, such wastes would be subject to LDR requirements. The purpose of this information brief is to clarify what waste management practices constitute removal from storage

  9. A cost analysis of microalgal biomass and biodiesel production in open raceways treating municipal wastewater and under optimum light wavelength.

    Science.gov (United States)

    Kang, Zion; Kim, Byung-Hyuk; Ramanan, Rishiram; Choi, Jong-Eun; Yang, Ji-Won; Oh, Hee-Mock; Kim, Hee-Sik

    2015-01-01

    Open raceway ponds are cost-efficient for mass cultivation of microalgae compared with photobioreactors. Although low-cost options like wastewater as nutrient source is studied to overcome the commercialization threshold for biodiesel production from microalgae, a cost analysis on the use of wastewater and other incremental increases in productivity has not been elucidated. We determined the effect of using wastewater and wavelength filters on microalgal productivity. Experimental results were then fitted into a model, and cost analysis was performed in comparison with control raceways. Three different microalgal strains, Chlorella vulgaris AG10032, Chlorella sp. JK2, and Scenedesmus sp. JK10, were tested for nutrient removal under different light wavelengths (blue, green, red, and white) using filters in batch cultivation. Blue wavelength showed an average of 27% higher nutrient removal and at least 42% higher chemical oxygen demand removal compared with white light. Naturally, the specific growth rate of microalgae cultivated under blue wavelength was on average 10.8% higher than white wavelength. Similarly, lipid productivity was highest in blue wavelength, at least 46.8% higher than white wavelength, whereas FAME composition revealed a mild increase in oleic and palmitic acid levels. Cost analysis reveals that raceways treating wastewater and using monochromatic wavelength would decrease costs from 2.71 to 0.73 $/kg biomass. We prove that increasing both biomass and lipid productivity is possible through cost-effective approaches, thereby accelerating the commercialization of low-value products from microalgae, like biodiesel.

  10. Growth Optimal Portfolio Selection Under Proportional Transaction Costs with Obligatory Diversification

    International Nuclear Information System (INIS)

    Duncan, T.; Pasik Duncan, B.; Stettner, L.

    2011-01-01

    A continuous time long run growth optimal or optimal logarithmic utility portfolio with proportional transaction costs consisting of a fixed proportional cost and a cost proportional to the volume of transaction is considered. The asset prices are modeled as exponent of diffusion with jumps whose parameters depend on a finite state Markov process of economic factors. An obligatory portfolio diversification is introduced, accordingly to which it is required to invest at least a fixed small portion of our wealth in each asset.

  11. Levelized Costs for Nuclear, Gas and Coal for Electricity, under the Mexican Scenario

    Energy Technology Data Exchange (ETDEWEB)

    Palacios, J.C.; Alonso, G.; Ramirez, R.; Gomez, A.; Ortiz, J.; Longoria, L.C.

    2004-10-06

    In the case of new nuclear power stations, it is necessary to pay special attention to the financial strategy that will be applied, time of construction, investment cost, and the discount and return rate. The levelized cost quantifies the unitary cost of the electricity (the kWh) generated during the lifetime of the nuclear power plant; and allows the immediate comparison with the cost of other alternative technologies. The present paper shows levelized cost for different nuclear technologies and it provides comparison among them as well as with gas and coal electricity plants. For the calculations we applied our own methodology to evaluate the levelized cost considering investment, fuel and operation and maintenance costs, making assumptions for the Mexican market, and taking into account the gas prices projections. The study also shows comparisons using different discount rates (5% and 10%), and some comparisons between our results and an OECD 1998 study. The results are i n good agreement and shows that nuclear option is cost competitive in Mexico on the basis of levelized costs.

  12. Levelized Costs for Nuclear, Gas and Coal for Electricity, under the Mexican Scenario

    International Nuclear Information System (INIS)

    Palacios, J.C.; Alonso, G.; Ramirez, R.; Gomez, A.; Ortiz, J.; Longoria, L.C.

    2004-01-01

    In the case of new nuclear power stations, it is necessary to pay special attention to the financial strategy that will be applied, time of construction, investment cost, and the discount and return rate. The levelized cost quantifies the unitary cost of the electricity (the kWh) generated during the lifetime of the nuclear power plant; and allows the immediate comparison with the cost of other alternative technologies. The present paper shows levelized cost for different nuclear technologies and it provides comparison among them as well as with gas and coal electricity plants. For the calculations we applied our own methodology to evaluate the levelized cost considering investment, fuel and operation and maintenance costs, making assumptions for the Mexican market, and taking into account the gas prices projections. The study also shows comparisons using different discount rates (5% and 10%), and some comparisons between our results and an OECD 1998 study. The results are i n good agreement and shows that nuclear option is cost competitive in Mexico on the basis of levelized costs

  13. Safety evaluations under the proposed US Safe Cosmetics and Personal Care Products Act of 2013: animal use and cost estimates.

    Science.gov (United States)

    Knight, Jean; Rovida, Costanca

    2014-01-01

    The proposed Safe Cosmetics and Personal Care Products Act of 2013 calls for a new evaluation program for cosmetic ingredients in the US, with the new assessments initially dependent on expanded animal testing. This paper considers possible testing scenarios under the proposed Act and estimates the number of test animals and cost under each scenario. It focuses on the impact for the first 10 years of testing, the period of greatest impact on animals and costs. The analysis suggests the first 10 years of testing under the Act could evaluate, at most, about 50% of ingredients used in cosmetics. Testing during this period would cost about $ 1.7-$ 9 billion and 1-11.5 million animals. By test year 10, alternative, high-throughput test methods under development are expected to be available, replacing animal testing and allowing rapid evaluation of all ingredients. Given the high cost in dollars and animal lives of the first 10 years for only about half of ingredients, a better choice may be to accelerate development of high-throughput methods. This would allow evaluation of 100% of cosmetic ingredients before year 10 at lower cost and without animal testing.

  14. Designing Energy Supply Chains with the P-graph Framework under Cost Constraints and Sustainability Considerations

    Science.gov (United States)

    A computer-aided methodology for designing sustainable supply chains is presented using the P-graph framework to develop supply chain structures which are analyzed using cost, the cost of producing electricity, and two sustainability metrics: ecological footprint and emergy. They...

  15. 47 CFR 27.1182 - Reimbursement under the Cost-Sharing Plan.

    Science.gov (United States)

    2010-10-01

    ... actual relocation costs. Specifically, the AWS relocator must submit, in the first instance, only the uniform cost data requested by the clearinghouse along with copies, without redaction, of the relocation...) Wholly outside its frequency band; or (2) Not within line of sight of the relocator's transmitting base...

  16. Cost-Benefit of E-Learning under ODL of Developing Economies ...

    African Journals Online (AJOL)

    Journal Home > Vol 13, No 2 (2012) >. Log in or Register to get access to full text downloads. ... Does it cost less to apply e-learning in open and distance learning (ODL) of developing economies? ... in the institutes' environment, photocopy of materials and the opportunity cost of time during working period for the student.

  17. Delivery of antiretroviral treatment services in India: Estimated costs incurred under the National AIDS Control Programme.

    Science.gov (United States)

    Agarwal, Reshu; Rewari, Bharat Bhushan; Shastri, Suresh; Nagaraja, Sharath Burugina; Rathore, Abhilakh Singh

    2017-04-01

    Competing domestic health priorities and shrinking financial support from external agencies necessitates that India's National AIDS Control Programme (NACP) brings in cost efficiencies to sustain the programme. In addition, current plans to expand the criteria for eligibility for antiretroviral therapy (ART) in India will have significant financial implications in the near future. ART centres in India provide comprehensive services to people living with HIV (PLHIV): those fulfilling national eligibility criteria and receiving ART and those on pre-ART care, i.e. not on ART. ART centres are financially supported (i) directly by the NACP; and (ii) indirectly by general health systems. This study was conducted to determine (i) the cost incurred per patient per year of pre-ART and ART services at ART centres; and (ii) the proportion of this cost incurred by the NACP and by general health systems. The study used national data from April 2013 to March 2014, on ART costs and non-ART costs (human resources, laboratory tests, training, prophylaxis and management of opportunistic infections, hospitalization, operational, and programme management). Data were extracted from procurement records and reports, statements of expenditure at national and state level, records and reports from ART centres, databases of the National AIDS Control Organisation, and reports on use of antiretroviral drugs. The analysis estimates the cost for ART services as US$ 133.89 (?8032) per patient per year, of which 66% (US$ 88.66, ?5320) is for antiretroviral drugs and 34% (US$ 45.23, ?2712) is for non-ART recurrent expenditure, while the cost for pre-ART care is US$ 33.05 (?1983) per patient per year. The low costs incurred for patients in ART and pre-ART care services can be attributed mainly to the low costs of generic drugs. However, further integration with general health systems may facilitate additional cost saving, such as in human resources.

  18. 76 FR 40336 - Fisheries of the Exclusive Economic Zone Off Alaska; Prohibited Species Donation Program

    Science.gov (United States)

    2011-07-08

    ... the Exclusive Economic Zone Off Alaska; Prohibited Species Donation Program AGENCY: National Marine... individuals under the prohibited species donation (PSD) program. Salmon and halibut are caught incidentally... 29 to the BSAI and GOA FMPs, respectively, authorize a salmon donation program and were approved by...

  19. LMFBR safety criteria: cost-benefit considerations under the constraint of an a priori risk criterion

    International Nuclear Information System (INIS)

    Hartung, J.

    1979-01-01

    The role of cost-benefit considerations and a priori risk criteria as determinants of Core Disruptive Accident (CDA)-related safety criteria for large LMFBR's is explored with the aid of quantitative risk and probabilistic analysis methods. A methodology is described which allows a large number of design and siting alternatives to be traded off against each other with the goal of minimizing energy generation costs subject to the constraint of both an a priori risk criterion and a cost-benefit criterion. Application of this methodology to a specific LMFBR design project is described and the results are discussed. 5 refs

  20. Inventory model with cash flow oriented and time-dependent holding cost under permissible delay in payments

    Directory of Open Access Journals (Sweden)

    Tripathi R.P.

    2013-01-01

    Full Text Available This study develops an inventory model for determining an optimal ordering policy for non-deteriorating items and time-dependent holding cost with delayed payments permitted by the supplier under inflation and time-discounting. The discounted cash flows approach is applied to study the problem analysis. Mathematical models have been derived under two different situations i.e. case I: The permissible delay period is less than cycle time for settling the account and case II: The permissible delay period is greater than or equal to cycle time for settling the account. An algorithm is used to obtain minimum total present value of the costs over the time horizon H. Finally, numerical example and sensitivity analysis demonstrate the applicability of the proposed model. The main purpose of this paper is to investigate the optimal cycle time and optimal payment time for an item so that annual total relevant cost is minimized.

  1. 49 CFR 1109.4 - Mandatory mediation in rate cases to be considered under the stand-alone cost methodology.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Mandatory mediation in rate cases to be considered... § 1109.4 Mandatory mediation in rate cases to be considered under the stand-alone cost methodology. (a) A... methodology must engage in non-binding mediation of its dispute with the railroad upon filing a formal...

  2. State estimation bias induced by optimization under uncertainty and error cost asymmetry is likely reflected in perception.

    Science.gov (United States)

    Shimansky, Y P

    2011-05-01

    It is well known from numerous studies that perception can be significantly affected by intended action in many everyday situations, indicating that perception and related decision-making is not a simple, one-way sequence, but a complex iterative cognitive process. However, the underlying functional mechanisms are yet unclear. Based on an optimality approach, a quantitative computational model of one such mechanism has been developed in this study. It is assumed in the model that significant uncertainty about task-related parameters of the environment results in parameter estimation errors and an optimal control system should minimize the cost of such errors in terms of the optimality criterion. It is demonstrated that, if the cost of a parameter estimation error is significantly asymmetrical with respect to error direction, the tendency to minimize error cost creates a systematic deviation of the optimal parameter estimate from its maximum likelihood value. Consequently, optimization of parameter estimate and optimization of control action cannot be performed separately from each other under parameter uncertainty combined with asymmetry of estimation error cost, thus making the certainty equivalence principle non-applicable under those conditions. A hypothesis that not only the action, but also perception itself is biased by the above deviation of parameter estimate is supported by ample experimental evidence. The results provide important insights into the cognitive mechanisms of interaction between sensory perception and planning an action under realistic conditions. Implications for understanding related functional mechanisms of optimal control in the CNS are discussed.

  3. Use of time and materials and cost reimbursement subcontracts for remedial actions under the alternative remedial contracting strategy contracts. Directive

    International Nuclear Information System (INIS)

    1992-01-01

    The directive is intended to establish agency guidance on the use of time and materials and cost reimbursement contracts for remedial actions in general and to provide specific instruction regarding the use of these approaches in subcontracting under the Alternative Remedial Contracting Strategy (ARCS) contracts

  4. Applying cost-sensitive classification for financial fraud detection under high class-imbalance

    CSIR Research Space (South Africa)

    Moepya, SO

    2014-12-01

    Full Text Available , sensitivity, specificity, recall and precision using PCA and Factor Analysis. Weighted Support Vector Machines (SVM) were shown superior to the cost-sensitive Naive Bayes (NB) and K-Nearest Neighbors classifiers....

  5. Assessment of DoD Electric Power Supply Options, Strategies, and Costs Under Retail Open Access

    National Research Council Canada - National Science Library

    Cameron, Pamela

    1997-01-01

    .... At the same time, significant changes in generation technology and reductions in fuel prices have reduced the cost of power from new generating facilities, driving down competitive prices for generation...

  6. Capital cost reimbursement to community hospitals under Federal health insurance programs.

    Science.gov (United States)

    Kinney, E D; Lefkowitz, B

    1982-01-01

    Issues in current capital cost reimbursement to community hospitals by Medicare and Medicaid are described, and options for change analyzed. Major reforms in the way the federal government pays for capital costs--in particular substitution of other methods of payment for existing depreciation reimbursement--could have significant impact on the structure of the health care system and on government expenditures. While such reforms are likely to engender substantial political opposition, they may be facilitated by broader changes in the reimbursement system.

  7. 14 CFR 1250.103 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Discrimination prohibited. 1250.103 Section 1250.103 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION IN... Discrimination prohibited. ...

  8. Cost Recommendation under Uncertainty in IQWiG's Efficiency Frontier Framework.

    Science.gov (United States)

    Corro Ramos, Isaac; Lhachimi, Stefan K; Gerber-Grote, Andreas; Al, Maiwenn J

    2017-02-01

    The National Institute for Quality and Efficiency in Health Care (IQWiG) employs an efficiency frontier (EF) framework to facilitate setting maximum reimbursable prices for new interventions. Probabilistic sensitivity analysis (PSA) is used when yes/no reimbursement decisions are sought based on a fixed threshold. In the IQWiG framework, an additional layer of complexity arises as the EF itself may vary its shape in each PSA iteration, and thus the willingness-to-pay, indicated by the EF segments, may vary. To explore the practical problems arising when, within the EF approach, maximum reimbursable prices for new interventions are sought through PSA. When the EF is varied in a PSA, cost recommendations for new interventions may be determined by the mean or the median of the distances between each intervention's point estimate and each EF. Implications of using these metrics were explored in a simulation study based on the model used by IQWiG to assess the cost-effectiveness of 4 antidepressants. Depending on the metric used, cost recommendations can be contradictory. Recommendations based on the mean can also be inconsistent. Results (median) suggested that costs of duloxetine, venlafaxine, mirtazapine, and bupropion should be decreased by €131, €29, €12, and €99, respectively. These recommendations were implemented and the analysis repeated. New results suggested keeping the costs as they were. The percentage of acceptable PSA outcomes increased 41% on average, and the uncertainty associated to the net health benefit was significantly reduced. The median of the distances between every intervention outcome and every EF is a good proxy for the cost recommendation that would be given should the EF be fixed. Adjusting costs according to the median increased the probability of acceptance and reduced the uncertainty around the net health benefit distribution, resulting in a reduced uncertainty for decision makers.

  9. Global Analysis of Changes in Water Supply Yields and Costs under Climate Change. A Case Study in China

    Energy Technology Data Exchange (ETDEWEB)

    Kirshen, P. [Department of Civil and Environmental Engineering and WaterSHED Center, Tufts University, Medford, Massachussetts, 02155 (United States); McCluskey, M. [CDM, Inc., Denver, Colorado (United States); Vogel, R. [Department of Civil and Environmental Engineering and WaterSHED Center, Tufts University, Medford, Massachussetts, 02155 (United States); Strzepek, K. [Department of Civil, Environmental and Architectural Engineering, and Environment and Behavior Program, Institute for Behavioral Science, University of Colorado, Boulder, Colorado, 80309 (United States)

    2005-02-01

    Using China as a case study, a methodology is presented to estimate the changes in yields and costs of present and future water production systems under climate change scenarios. Yield is important to consider because it measures the actual supply available from a river basin. Costs are incurred in enhancing the natural yield of river basins by the construction and operation of reservoirs and ground water pumping systems. The interaction of ground and surface waters within a river basin and instream flow maintenance are also modeled. The water demands considered are domestic, irrigation, and instream flow needs. We found that under climate change the maximum yields of some basins in China may increase or decrease, depending upon location, and that in some basins it may cost significantly more or it may not be possible to meet the demands. While our results for China could be improved with more hydrologic and economic data, we believe that the cost curves developed have suitable accuracy for initial analysis of water supply costs in Integrated Assessment Models.

  10. Life-cycle cost assessment of optimally designed reinforced concrete buildings under seismic actions

    International Nuclear Information System (INIS)

    Mitropoulou, Chara Ch.; Lagaros, Nikos D.; Papadrakakis, Manolis

    2011-01-01

    Life-cycle cost analysis (LCCA) is an assessment tool for studying the performance of systems in many fields of engineering. In earthquake engineering LCCA demands the calculation of the cost components that are related to the performance of the structure in multiple earthquake hazard levels. Incremental static and dynamic analyses are two procedures that can be used for estimating the seismic capacity of a structural system and can therefore be incorporated into the LCCA methodology. In this work the effect of the analysis procedure, the number of seismic records imposed, the performance criterion used and the structural type (regular or irregular) is investigated, on the life-cycle cost analysis of 3D reinforced concrete structures. Furthermore, the influence of uncertainties on the seismic response of structural systems and their impact on LCCA is examined. The uncertainty on the material properties, the cross-section dimensions and the record-incident angle is taking into account with the incorporation of the Latin hypercube sampling method into the incremental dynamic analysis procedure. In addition, the LCCA methodology is used as an assessment tool for the designs obtained by means of prescriptive and performance-based optimum design methodologies. The first one is obtained from a single-objective optimization problem, where the initial construction cost was the objective to be minimized, while the second one as a two-objective optimization problem where the life-cycle cost was the additional objective also to be minimized.

  11. Life cycle cost analysis of HPVT air collector under different Indian climatic conditions

    International Nuclear Information System (INIS)

    Raman, Vivek; Tiwari, G.N.

    2008-01-01

    In this communication, a study is carried out to evaluate an annual thermal and exergy efficiency of a hybrid photovoltaic thermal (HPVT) air collector for different Indian climate conditions, of Srinagar, Mumbai, Jodhpur, New Delhi and Banglore. The study has been based on electrical, thermal and exergy output of the HPVT air collector. Further, the life cycle analysis in terms of cost/kWh has been carried out. The main focus of the study is to see the effect of interest rate, life of the HPVT air collector, subsidy, etc. on the cost/kWh HPVT air collector. A comparison is made keeping in view the energy matrices. The study reveals that (i) annual thermal and electrical efficiency decreases with increase in solar radiation and (ii) the cost/kWh is higher in case of exergy when compared with cost/kWh on the basis of thermal energy for all climate conditions. The cost/kWh for climate conditions of Jodhpur is most economical

  12. Traditional Commerce Versus Electronic Commerce: A Case Study Under The Logistics Costs Management View

    Directory of Open Access Journals (Sweden)

    Marcos Antônio de Souza

    2014-08-01

    Full Text Available The aim of this article is to see how a large Brazilian company of the retail sector makes the measurement and analysis of logistics costs of both its physical operations (traditional trade as their virtual transactions (e-commerce. The research has been conducted in the contributions of strategic cost management for business sustainability. This is an unique descriptive case study, with a qualitative approach, performed in the 2nd half of 2013. Data were collected through interviews, document analysis and in situ observations. Data analyzes occurred by comparative interpretations. The main results showed no significant differences in the analysis and measurement of logistics costs between the two forms of trading. This can be explained partly by the fact that the company does not deal with electronic commerce differently in relation to the management of logistics costs. That is, both the operations of the virtual store as physical stores share the same logistics structure. Additional logistics costs in e-commerce are offset by higher margin practiced in this business model.

  13. Nuclear Activities (Prohibitions) Act 1983

    International Nuclear Information System (INIS)

    1983-01-01

    The purpose of this Act is to protect the health and safety of the people of Victoria and its environment by prohibiting nuclear activities from being carried out and regulating the possession of certain nuclear material in a manner consistent with assisting Australia in meeting its international nuclear non-proliferation objectives. (NEA) [fr

  14. Cartel prohibition may increase prices

    NARCIS (Netherlands)

    Haan, Marco A.

    In this paper, we show that a policy that forbids cartels may benefit dominant firms, and hurt consumers. When cartels are prohibited, an incumbent monopolist can commit not to form a cartel should a new entrant enter the market. This reduces the entry threat, which implies that entry occurs less

  15. 50 CFR 216.82 - Dogs prohibited.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Dogs prohibited. 216.82 Section 216.82... Pribilof Islands Administration § 216.82 Dogs prohibited. In order to prevent molestation of fur seal herds, the landing of any dogs at Pribilof Islands is prohibited. [41 FR 49488, Nov. 9, 1976. Redesignated at...

  16. 24 CFR 891.685 - Prohibited relationships.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Prohibited relationships. 891.685... and Individuals-Section 162 Assistance § 891.685 Prohibited relationships. The requirements for prohibited relationships for 202/162 projects are provided in § 891.130. ...

  17. 45 CFR 1151.21 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 1151.21 Section 1151.21... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination Prohibited Accessibility § 1151.21 Discrimination prohibited. No qualified handicapped person shall, because...

  18. 15 CFR 8b.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Discrimination prohibited. 8b.4 Section 8b.4 Commerce and Foreign Trade Office of the Secretary of Commerce PROHIBITION OF DISCRIMINATION... Provisions § 8b.4 Discrimination prohibited. (a) General. No qualified handicapped individual shall, on the...

  19. 15 CFR 8b.11 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Discrimination prohibited. 8b.11 Section 8b.11 Commerce and Foreign Trade Office of the Secretary of Commerce PROHIBITION OF DISCRIMINATION... Practices § 8b.11 Discrimination prohibited. (a) General. (1) No qualified handicapped individual shall, on...

  20. 15 CFR 8b.16 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Discrimination prohibited. 8b.16 Section 8b.16 Commerce and Foreign Trade Office of the Secretary of Commerce PROHIBITION OF DISCRIMINATION... Accessibility § 8b.16 Discrimination prohibited. No qualified handicapped individual shall, because a recipient...

  1. 45 CFR 1151.31 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 1151.31 Section 1151.31... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination Prohibited Employment § 1151.31 Discrimination prohibited. (a) No qualified handicapped person shall, on the...

  2. Optimal ordering quantities for substitutable deteriorating items under joint replenishment with cost of substitution

    Science.gov (United States)

    Mishra, Vinod Kumar

    2017-09-01

    In this paper we develop an inventory model, to determine the optimal ordering quantities, for a set of two substitutable deteriorating items. In this inventory model the inventory level of both items depleted due to demands and deterioration and when an item is out of stock, its demands are partially fulfilled by the other item and all unsatisfied demand is lost. Each substituted item incurs a cost of substitution and the demands and deterioration is considered to be deterministic and constant. Items are order jointly in each ordering cycle, to take the advantages of joint replenishment. The problem is formulated and a solution procedure is developed to determine the optimal ordering quantities that minimize the total inventory cost. We provide an extensive numerical and sensitivity analysis to illustrate the effect of different parameter on the model. The key observation on the basis of numerical analysis, there is substantial improvement in the optimal total cost of the inventory model with substitution over without substitution.

  3. Method of evaluation of solar collector cost under fuel price change

    International Nuclear Information System (INIS)

    Klychev, Sh. I.; Sadykova, N. S.; Saifiev, A. U.; Ismanzhanov, A. I.; Samiev, M.

    2013-01-01

    When we take into account the problems of large-scale use of solar energy, the matters of economic perspectives of solar plants in the future become vital. We present the method on whose basis evaluation of the cost of solar collectors is performed taking into account the change in the fuel prices. The method is based on the approach to evaluation of the cost of energy generated by the solar plants offered previously by the authors. Assuming that the components of expenditures for production are not changed, we obtained that the cost of solar collectors will grow, at approximately the same ratio as the growth of the prices for fuel (energy). Thus, the problem of creation of the economically effective solar collectors should be solved already today, at the existing prices for materials and fuel. At present, it is assumed that competitiveness of the solar plants will increase with the growth of the fuel prices. (authors)

  4. Measuring the environmental benefits of hydrogen transportation fuel cycles under uncertainty about external costs

    International Nuclear Information System (INIS)

    Chernyavs'ka, Liliya; Gulli, Francesco

    2010-01-01

    In this paper, we attempt to measure the environmental benefits of hydrogen deployment in the transportation sector. We compare the hydrogen pathways to the conventional transportation fuel cycles in terms of external costs, estimated using the results of the most accurate methodologies available in this field. The central values of performed analysis bring us ambiguous results. The external cost of the best conventional solution ('oil to diesel hybrid internal-combustion engine') in some cases is just higher and in others just lower than that of the best fossil fuel to hydrogen solution ('natural gas to hydrogen fuel cell'). Nevertheless, by accounting for the uncertainty about external costs, we are able to remove this ambiguity highlighting that the hydrogen pathway provides significant environmental benefits ,especially in densely populated areas, assuming 100% city driving.

  5. The French biofuels mandates under cost uncertainty - an assessment based on robust optimization

    International Nuclear Information System (INIS)

    Lorne, Daphne; Tchung-Ming, Stephane

    2012-01-01

    This paper investigates the impact of primary energy and technology cost uncertainty on the achievement of renewable and especially biofuel policies - mandates and norms - in France by 2030. A robust optimization technique that allows to deal with uncertainty sets of high dimensionality is implemented in a TIMES-based long-term planning model of the French energy transport and electricity sectors. The energy system costs and potential benefits (GHG emissions abatements, diversification) of the French renewable mandates are assessed within this framework. The results of this systemic analysis highlight how setting norms and mandates allows to reduce the variability of CO 2 emissions reductions and supply mix diversification when the costs of technological progress and prices are uncertain. Beyond that, we discuss the usefulness of robust optimization in complement of other techniques to integrate uncertainty in large-scale energy models. (authors)

  6. Prohibition as ontological basis of the Russian legal reality

    Directory of Open Access Journals (Sweden)

    Andrey V. Skorobogatov

    2016-09-01

    Full Text Available Objective to identify characteristics of the nature content and functioning of prohibition in the legal reality of Russia. nbsp Methods the methodological basis of research is the dialectical approach to cognition of social phenomena allowing to analyze them in historical development and functioning in the context of the totality of objective and subjective factors as well as a postmodern paradigm giving the opportunity to explore the legal reality at different levels. Dialectical approach and postmodern paradigm determined the choice of specific research methods comparative hermeneutic discursive. Results the paper proposes a definition of prohibition as a state socio volitional constraining limiting means that under the threat of legal liability is intended to prevent the wrongful act of the subject physical or legal entity and ensure the maintenance of law and order. Prohibition is a necessary means of ensuring the discipline of public relations and the consolidation of legal values designed to assure the effectiveness of legal regulation. Scientific novelty for the first time the article shows that prohibition as a legal category is the ontological basis of legal reality and acts as a determining factor in the content and focus not only of lawmaking and law enforcement but legal behavior as well. Practical significance the main provisions and conclusions of the article can be used in research and teaching when considering questions about the nature content and functioning of prohibitions.

  7. Integral Cost-Benefit Analysis of Maglev Rail Projects Under Market Imperfections

    Directory of Open Access Journals (Sweden)

    J. Paul Elhorst

    2008-07-01

    Full Text Available This article evaluates a new mode of high speed ground transportation, the magnetic levitation rail system (Maglev. The outcomes of this evaluation provide policy information on the interregional redistribution of employment and population and the national welfare improvement of two Dutch urban-conglomeration and two Dutch core-periphery projects. This article also compares the results of an integral cost- benefit analysis with those of a conventional cost-benefit analysis and concludes that the additional economic benefits due to market imperfections vary from –1% to +38% of the direct transport benefits, depending on the type of regions connected and the general condition of the economy.

  8. 21 CFR 189.5 - Prohibited cattle materials.

    Science.gov (United States)

    2010-04-01

    ... passed, it was found to be not adulterated. (3) Mechanically Separated (MS)(Beef) means a meat food... were created. (3) Records must be retained at the manufacturing or processing establishment or at a... deemed adulterated under section 402(a)(3) of the act. (3) Food additive status. Prohibited cattle...

  9. 19 CFR 201.130 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-04-01

    ....130 Section 201.130 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF... Conducted by the U.S. International Trade Commission § 201.130 General prohibitions against discrimination... in, be denied the benefits of, or otherwise be subjected to discrimination under any program or...

  10. 29 CFR 1977.4 - Persons prohibited from discriminating.

    Science.gov (United States)

    2010-07-01

    ... OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 General § 1977.4 Persons prohibited from discriminating. Section 11....4 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... employee” because the employee has exercised rights under the Act. Section 3(4) of the Act defines “person...

  11. Virus Resistance Is Not Costly in a Marine Alga Evolving under Multiple Environmental Stressors

    Directory of Open Access Journals (Sweden)

    Sarah E. Heath

    2017-03-01

    Full Text Available Viruses are important evolutionary drivers of host ecology and evolution. The marine picoplankton Ostreococcus tauri has three known resistance types that arise in response to infection with the Phycodnavirus OtV5: susceptible cells (S that lyse following viral entry and replication; resistant cells (R that are refractory to viral entry; and resistant producers (RP that do not all lyse but maintain some viruses within the population. To test for evolutionary costs of maintaining antiviral resistance, we examined whether O. tauri populations composed of each resistance type differed in their evolutionary responses to several environmental drivers (lower light, lower salt, lower phosphate and a changing environment in the absence of viruses for approximately 200 generations. We did not detect a cost of resistance as measured by life-history traits (population growth rate, cell size and cell chlorophyll content and competitive ability. Specifically, all R and RP populations remained resistant to OtV5 lysis for the entire 200-generation experiment, whereas lysis occurred in all S populations, suggesting that resistance is not costly to maintain even when direct selection for resistance was removed, or that there could be a genetic constraint preventing return to a susceptible resistance type. Following evolution, all S population densities dropped when inoculated with OtV5, but not to zero, indicating that lysis was incomplete, and that some cells may have gained a resistance mutation over the evolution experiment. These findings suggest that maintaining resistance in the absence of viruses was not costly.

  12. Integral cost-benefit analysis of Maglev technology under market imperfections

    NARCIS (Netherlands)

    Elhorst, J. Paul; Oosterhaven, Jan; Romp, Ward E.

    2001-01-01

    The aim of this article is to assess a proposed new mode of guided high speed ground transportation, the magnetic levitation rail system (Maglev), and to compare the results of a partial cost-benefit analysis with those of an integral CBA. We deal with an urbanconglomeration as well as a

  13. Pricing European option with transaction costs under the fractional long memory stochastic volatility model

    Science.gov (United States)

    Wang, Xiao-Tian; Wu, Min; Zhou, Ze-Min; Jing, Wei-Shu

    2012-02-01

    This paper deals with the problem of discrete time option pricing using the fractional long memory stochastic volatility model with transaction costs. Through the 'anchoring and adjustment' argument in a discrete time setting, a European call option pricing formula is obtained.

  14. Marginal CO2 cost pass-through under imperfect competition in power markets

    International Nuclear Information System (INIS)

    Chernyavs'ka, Liliya; Gulli, Francesco

    2008-01-01

    In line with economic theory, carbon ETS determines a rise in marginal cost equal to the carbon opportunity cost regardless of whether carbon allowances are allocated free of charge or not. This paper aims at evaluating to what extent firms in imperfectly competitive markets will pass-through into electricity prices the increase in cost. By using the load duration curve approach and the dominant firm with competitive fringe model, we show that the result is ambiguous. The increase in price can be either lower or higher than the marginal CO 2 cost, depending on several structural factors: the degree of market concentration, the available capacity (whether there is excess capacity or not), the power plant mix in the market and the power demand level (peak vs. off-peak hours). The empirical analysis of the Italian context (an emblematic case of imperfectly competitive market), which can be split into four sub-markets with different structural features, provides a contribution supporting the model predictions. Market power, therefore, would determine a significant deviation from the 'full pass-through' rule but we cannot know the sign of this deviation, a priori, i.e. without before taking carefully into account the structural features of the power market. (author)

  15. 42 CFR 413.106 - Reasonable cost of physical and other therapy services furnished under arrangements.

    Science.gov (United States)

    2010-10-01

    ... of therapy, to therapists working full time in an employment relationship. (2) Fringe benefit and... geographical area in which the services are furnished and a standard travel allowance. (3) If therapy services... 42 Public Health 2 2010-10-01 2010-10-01 false Reasonable cost of physical and other therapy...

  16. Strategic design of cost savings guarantee in energy performance contracting under uncertainty

    International Nuclear Information System (INIS)

    Deng, Qianli; Jiang, Xianglin; Cui, Qingbin; Zhang, Limao

    2015-01-01

    Highlights: • A methodology is proposed to assist Energy Service Companies to maintain competitiveness in winning bids. • Uncertainties within the energy cost savings are modeled stochastically using the Monte-Carlo simulation. • A strategic energy savings guarantee design curve is derived, where all points return as appropriate guarantees. • A campus case is presented to demonstrate the applicability for finding appropriate guaranteed savings value. - Abstract: Among the key barriers to profit in Energy Performance Contracting (EPC) are uncertainties about attaining the realized energy cost savings and potential disputes over the guaranteed cost savings. In this paper, a methodology has been proposed to assist the Energy Service Company (ESCO): (1) to evaluate the risk threshold if the guarantee has already been made, and (2) to determine the guarantee design, if the guarantee has not been made yet, that not only promises the ESCO’s profitability from EPC but also maintains its competitiveness to win the bid. Uncertainties within the energy cost savings are modeled stochastically using Monte-Carlo simulation, taking both the energy price fluctuation and the facility performance variability into account. Based on that, a strategic energy savings guarantee design curve is derived, that all the points on it would return as appropriate guarantees. Finally, a campus case is presented to demonstrate the applicability for finding the appropriate guaranteed savings value. This method is also worth popularizing in similar performance-based projects

  17. Causation of Genuinely Social Costs: Pigou Enabling Coase Through the Causation Principles Underlying Environmental Taxation

    NARCIS (Netherlands)

    D. Heine (Dirk)

    2017-01-01

    markdownabstractWhen a producer manufactures a polluting product that is demanded by a consumer, who is causing that pollution? The producer, the consumer, or both? And if the state then imposes policies to mitigate the emissions but the producer passes the abatement costs onto its customers, does

  18. A case study of cost-efficient staffing under annualized hours

    NARCIS (Netherlands)

    van der Veen, Egbert; Hans, Elias W.; Veltman, Bart; Berrevoets, Leo M.; Berden, Hubert J.J.M.

    2014-01-01

    We propose a mathematical programming formulation that incorporates annualized hours and shows to be very flexible with regard to modeling various contract types. The objective of our model is to minimize salary cost, thereby covering workforce demand, and using annualized hours. Our model is able

  19. A case study of cost-efficient staffing under annualized hours

    NARCIS (Netherlands)

    van der Veen, Egbert; Hans, Elias W.; Veltman, Bart; Berrevoets, L.M.; Berden, H.J.J.M.

    We propose a mathematical programming formulation that incorporates annualized hours and shows to be very flexible with regard to modeling various contract types. The objective of our model is to minimize salary cost, thereby covering workforce demand, and using annualized hours. Our model is able

  20. Analyzing cost efficient production behavior under economies of scope : A nonparametric methodology

    NARCIS (Netherlands)

    Cherchye, L.J.H.; de Rock, B.; Vermeulen, F.M.P.

    2008-01-01

    In designing a production model for firms that generate multiple outputs, we take as a starting point that such multioutput production refers to economies of scope, which in turn originate from joint input use and input externalities. We provide a nonparametric characterization of cost-efficient

  1. Analyzing Cost Efficient Production Behavior Under Economies of Scope : A Nonparametric Methodology

    NARCIS (Netherlands)

    Cherchye, L.J.H.; de Rock, B.; Vermeulen, F.M.P.

    2006-01-01

    In designing a production model for firms that generate multiple outputs, we take as a starting point that such multi-output production refers to economies of scope, which in turn originate from joint input use and input externalities. We provide a nonparametric characterization of cost efficient

  2. Wood pellet production costs under Austrian and in comparison to Swedish framework conditions

    NARCIS (Netherlands)

    Obernberger, I.; Thek, G.

    2004-01-01

    Owing to the rapidly increasing importance of pellets as high-quality biomass fuel in Austria and Europe within the last years, many companies, mainly from the wood industry, are thinking of entering this market. The calculation of the production costs before starting a pellet plant is essential for

  3. Online Cooperative Promotion and Cost Sharing Policy under Supply Chain Competition

    Directory of Open Access Journals (Sweden)

    Erjiang E

    2016-01-01

    Full Text Available This paper studies online cooperative promotion and cost sharing decisions in competing supply chains. We consider a model of one B2C e-commerce platform and two supply chains each consisting of a supplier and an online retailer. The problem is studied using a multistage game. Firstly, the e-commerce platform carries out the cooperative promotion and sets the magnitude of markdown (the value of e-coupon. Secondly, each retailer and his supplier determine the fraction of promotional cost sharing when they have different bargaining power. Lastly, the retailers decide whether to participate in the cooperative promotion campaign. We show that the retailers are likely to participate in the promotion if consumers become more price-sensitive. However, it does not imply that the retailers can benefit from the price promotion; the promotion decision game resembles the classical prisoner’s dilemma game. The retailers and suppliers can benefit from the cooperative promotion by designing an appropriate cost sharing contract. For a supply chain, the bargaining power between supplier and retailer, consumer price sensitivity, and competition intensity affect the fraction of the promotional cost sharing. We also find that equilibrium value of e-coupon set by the e-commerce platform is not optimal for all the parties.

  4. Estimating cost efficiency of Turkish commercial banks under unobserved heterogeneity with stochastic frontier models

    Directory of Open Access Journals (Sweden)

    Hakan Gunes

    2016-12-01

    Full Text Available This study aims to investigate the cost efficiency of Turkish commercial banks over the restructuring period of the Turkish banking system, which coincides with the 2008 financial global crisis and the 2010 European sovereign debt crisis. To this end, within the stochastic frontier framework, we employ true fixed effects model, where the unobserved bank heterogeneity is integrated in the inefficiency distribution at a mean level. To select the cost function with the most appropriate inefficiency correlates, we first adopt a search algorithm and then utilize the model averaging approach to verify that our results are not exposed to model selection bias. Overall, our empirical results reveal that cost efficiencies of Turkish banks have improved over time, with the effects of the 2008 and 2010 crises remaining rather limited. Furthermore, not only the cost efficiency scores but also impacts of the crises on those scores appear to vary with regard to bank size and ownership structure, in accordance with much of the existing literature.

  5. Optimal Willingness to Supply Wholesale Electricity Under Asymmetric Linearized Marginal Costs

    Directory of Open Access Journals (Sweden)

    David Hudgins

    2012-01-01

    Full Text Available This analysis derives the profit-maximizing willingness to supply functions for single-plant and multi-plant wholesale electricity suppliers that all incur linear marginal costs. The optimal strategy must result in linear residual demand functions in the absence of capacity constraints. This necessarily leads to a linear pricing rule structure that can be used by firm managers to construct their offer curves and to serve as a benchmark to evaluate firm profit-maximizing behavior. The procedure derives the cost functions and the residual demand curves for merged or multi-plant generators, and uses these to construct the individual generator plant offer curves for a multi-plant firm.

  6. Convenience polyandry or convenience polygyny? Costly sex under female control in a promiscuous primate

    OpenAIRE

    Huchard, Elise; Canale, Cindy I.; Le Gros, Chloé; Perret, Martine; Henry, Pierre-Yves; Kappeler, Peter M.

    2011-01-01

    Classic sex roles depict females as choosy, but polyandry is widespread. Empirical attempts to understand the evolution of polyandry have often focused on its adaptive value to females, whereas ‘convenience polyandry’ might simply decrease the costs of sexual harassment. We tested whether constraint-free female strategies favour promiscuity over mating selectivity through an original experimental design. We investigated variation in mating behaviour in response to a reversible alteration of s...

  7. Convenience polyandry or convenience polygyny? Costly sex under female control in a promiscuous primate.

    Science.gov (United States)

    Huchard, Elise; Canale, Cindy I; Le Gros, Chloé; Perret, Martine; Henry, Pierre-Yves; Kappeler, Peter M

    2012-04-07

    Classic sex roles depict females as choosy, but polyandry is widespread. Empirical attempts to understand the evolution of polyandry have often focused on its adaptive value to females, whereas 'convenience polyandry' might simply decrease the costs of sexual harassment. We tested whether constraint-free female strategies favour promiscuity over mating selectivity through an original experimental design. We investigated variation in mating behaviour in response to a reversible alteration of sexual dimorphism in body mass in the grey mouse lemur, a small primate where female brief sexual receptivity allows quantifying polyandry. We manipulated body condition in captive females, predicting that convenience polyandry would increase when females are weaker than males, thus less likely to resist their solicitations. Our results rather support the alternative hypothesis of 'adaptive polyandry': females in better condition are more polyandrous. Furthermore, we reveal that multiple mating incurs significant energetic costs, which are strikingly symmetrical between the sexes. Our study shows that mouse lemur females exert tight control over mating and actively seek multiple mates. The benefits of remating are nevertheless not offset by its costs in low-condition females, suggesting that polyandry is a flexible strategy yielding moderate fitness benefits in this small mammal.

  8. Fair value or cost-based measurement for PPE and IP: evidence from accounting practice under IFRS

    OpenAIRE

    Fonseca, Maria

    2007-01-01

    Some standards permit a choice between different measurement bases. IAS 16 and IAS 40 allow entities to choose between fair value and cost-based measurement for property, plant and equipment (PPE) and investment property (IP), respectively. This study analyzes the accounting practice concerning measurement of PPE and IP after recognition, under IFRS. The sample was extracted from stock exchange listed European companies included in the S&P Europe 350 Index. Data was hand collec...

  9. Incorrect modeling of the failure process of minimally repaired systems under random conditions: The effect on the maintenance costs

    International Nuclear Information System (INIS)

    Pulcini, Gianpaolo

    2015-01-01

    This note investigates the effect of the incorrect modeling of the failure process of minimally repaired systems that operates under random environmental conditions on the costs of a periodic replacement maintenance. The motivation of this paper is given by a recently published paper, where a wrong formulation of the expected cost for unit time under a periodic replacement policy is obtained. This wrong formulation is due to the incorrect assumption that the intensity function of minimally repaired systems that operate under random conditions has the same functional form as the failure rate of the first failure time. This produced an incorrect optimization of the replacement maintenance. Thus, in this note the conceptual differences between the intensity function and the failure rate of the first failure time are first highlighted. Then, the correct expressions of the expected cost and of the optimal replacement period are provided. Finally, a real application is used to measure how severe can be the economical consequences caused by the incorrect modeling of the failure process.

  10. Is a diabetes pay-for-performance program cost-effective under the National Health Insurance in Taiwan?

    Science.gov (United States)

    Tan, Elise Chia-Hui; Pwu, Raoh-Fang; Chen, Duan-Rung; Yang, Ming-Chin

    2014-03-01

    In October 2001, a pay-for-performance (P4P) program for diabetes was implemented by the National Health Insurance (NHI), a single-payer program, in Taiwan. However, only limited information is available regarding the influence of this program on the patient's health-related quality of life. The aim of this study was to estimate the costs and consequences of enrolling patients in the P4P program from a single-payer perspective. A retrospective observational study of 529 diabetic patients was conducted between 2004 and 2005. The data used in the study were obtained from the National Health Interview Survey (NHIS) in Taiwan. Direct cost data were obtained from NHI claims data, which were linked to respondents in the NHIS using scrambled individual identification. The generic SF36 health instrument was employed to measure the quality-of-life-related health status and transformed into a utility index. Patients enrolled in the P4P program for at least 3 months were categorized as the P4P group. Following propensity score matching, 260 patients were included in the study. Outcomes included life-years, quality-adjusted life-years (QALYs), diabetes-related medical costs, overall medical costs, and incremental cost-effectiveness ratios (ICERs). A single-payer perspective was assumed, and costs were expressed in US dollars. Nonparametric bootstrapping was conducted to estimate confidence intervals for cost-effectiveness ratios. Following matching, no significant difference was noted between two groups with regard to the patients' age, gender, education, family income, smoking status, BMI, or whether insulin was used. The P4P group had an increase of 0.08 (95 % CI 0.077-0.080) in QALYs, and the additional diabetes-related medical cost was US$422.74 (95 % CI US$413.58-US$435.05), yielding an ICER of US$5413.93 (95 % CI US$5226.83-US$5562.97) per QALY gained. Our results provides decision makers with valuable information regarding the impact of the P4P program of diabetes care

  11. A case study of cost-efficient staffing under annualized hours.

    Science.gov (United States)

    van der Veen, Egbert; Hans, Erwin W; Veltman, Bart; Berrevoets, Leo M; Berden, Hubert J J M

    2015-09-01

    We propose a mathematical programming formulation that incorporates annualized hours and shows to be very flexible with regard to modeling various contract types. The objective of our model is to minimize salary cost, thereby covering workforce demand, and using annualized hours. Our model is able to address various business questions regarding tactical workforce planning problems, e.g., with regard to annualized hours, subcontracting, and vacation planning. In a case study for a Dutch hospital two of these business questions are addressed, and we demonstrate that applying annualized hours potentially saves up to 5.2% in personnel wages annually.

  12. MODERN APPROACHES TO INTELLECTUAL PROPERTY COST ESTIMATION UNDER CRISIS CONDITIONS FROM CONSUMER QUALITY PRESERVATION VIEWPOINT

    Directory of Open Access Journals (Sweden)

    I. N. Alexandrov

    2011-01-01

    Full Text Available Various intellectual property (IP estimation approaches and innovations in this field are discussed. Problem situations and «bottlenecks» in the economic mechanism of transformation of innovations into useful products and services are defined. Main international IP evaluation methods are described, particular attention being paid to «Quick Inside» program defined as latest generation global expert system. IP income and expense evaluation methods used in domestic practice are discussed. Possibility of using the Black-Scholes optional model to estimate costs of non-material assets is studied.

  13. 25 CFR 1000.228 - What are examples of waivers prohibited by law?

    Science.gov (United States)

    2010-04-01

    ... ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.228 What are examples of waivers prohibited by law...

  14. An extended cost-effectiveness analysis of schizophrenia treatment in India under universal public finance.

    Science.gov (United States)

    Raykar, Neha; Nigam, Aditi; Chisholm, Dan

    2016-01-01

    Schizophrenia remains a priority condition in mental health policy and service development because of its early onset, severity and consequences for affected individuals and households. This paper reports on an 'extended' cost-effectiveness analysis (ECEA) for schizophrenia treatment in India, which seeks to evaluate through a modeling approach not only the costs and health effects of intervention but also the consequences of a policy of universal public finance (UPF) on health and financial outcomes across income quintiles. Using plausible values for input parameters, we conclude that health gains from UPF are concentrated among the poorest, whereas the non-health gains in the form of out-of-pocket private expenditures averted due to UPF are concentrated among the richest income quintiles. Value of insurance is the highest for the poorest quintile and declines with income. Universal public finance can play a crucial role in ameliorating the adverse economic and social consequences of schizophrenia and its treatment in resource-constrained settings where health insurance coverage is generally poor. This paper shows the potential distributional and financial risk protection effects of treating schizophrenia.

  15. 24 CFR 1000.420 - May grants made by HUD under section 603 of NAHASDA be used to pay net interest costs incurred...

    Science.gov (United States)

    2010-04-01

    ... section 603 of NAHASDA be used to pay net interest costs incurred when issuing notes or other obligations... Activities § 1000.420 May grants made by HUD under section 603 of NAHASDA be used to pay net interest costs incurred when issuing notes or other obligations? Yes. Other costs that can be paid using grant funds...

  16. From Polluter Pays to Provider Gets: Distribution of Rights and Costs under Payments for Ecosystem Services

    Directory of Open Access Journals (Sweden)

    Volker Mauerhofer

    2013-12-01

    Full Text Available Should society have the right to freely available clean air and water, or should people be required to pay for these as commodities just as they do for many other goods or services that they consume? With this question and further questions on environmental governance in mind, we reviewed the paradigm shift in natural resource management from the polluter pays principle (PPP, which focuses on polluters and enforcement of thresholds, to the principle of payments for ecosystem services (PES, which emphasizes provider-based economic approaches. Given that there are conflicts of interest over natural resources and ecosystem services (ESs, these conflicts could be resolved through rights and/or cost assignments via third-party intervention, i.e., by the "state," or through private compensation beyond initial regulation and state-initiated assignments of cost. Our analysis includes an in-depth literature review and a description of existing policies on ESs. We also examine the so-called Coase theorem based on a "neutral" situation where no rights or costs are distributed in advance. This theorem provides room for the PPP approaches and the provider-gets approaches. Both of these approaches should ensure, given certain assumptions, an economically efficient allocation of resources; however, they still ignore two indispensable issues, namely, the ecologically sustainable scale and inherent qualities of ecosystems and the distributional effects. With regard to the relationship between these two sets of approaches and their respective relationship to the legal framework, PES programs can evolve instead of PPP where no regulations are in place, existing regulations are deemed to be insufficiently formulated, or regulations are not enforced at all. We also further address some critical issues that can arise when PES programs evolve instead of PPP in practice, such as the general necessity of PES to coexist with basic rights and legal obligations

  17. On the costs of self-interested economic behavior : How does stinginess get under the skin?

    NARCIS (Netherlands)

    Dunn, Elizabeth W.; Ashton-James, Claire E.; Hanson, Margaret D.; Aknin, Lara B.

    The present study examined how financial decisions 'get under the skin'. Participants played an economic game in which they could donate some of their payment to another student. Affect was measured afterward and salivary cortisol was measured before and afterward. Participants who kept more money

  18. Benefits and costs of oil palm expansion in Central Kalimantan, Indonesia, under different policy scenarios

    NARCIS (Netherlands)

    Sumarga, Elham; Hein, Lars

    2016-01-01

    Deforestation and oil palm expansion in Central Kalimantan province are among the highest in Indonesia. This study examines the physical and monetary impacts of oil palm expansion in Central Kalimantan up to 2025 under three policy scenarios. Our modelling approach combines a spatial logistic

  19. Economic costs of extratropical storms under climate change: An application of FUND

    NARCIS (Netherlands)

    Narita, D.; Anthoff, D.; Tol, R.S.J.

    2010-01-01

    Extratropical cyclones have attracted some attention in climate policy circles as a possible significant damage factor of climate change. This study conducts an assessment of economic impacts of increased storm activities under climate change with the integrated assessment model FUND 3.5. In the

  20. An efficient heuristic method for dynamic portfolio selection problem under transaction costs and uncertain conditions

    Science.gov (United States)

    Najafi, Amir Abbas; Pourahmadi, Zahra

    2016-04-01

    Selecting the optimal combination of assets in a portfolio is one of the most important decisions in investment management. As investment is a long term concept, looking into a portfolio optimization problem just in a single period may cause loss of some opportunities that could be exploited in a long term view. Hence, it is tried to extend the problem from single to multi-period model. We include trading costs and uncertain conditions to this model which made it more realistic and complex. Hence, we propose an efficient heuristic method to tackle this problem. The efficiency of the method is examined and compared with the results of the rolling single-period optimization and the buy and hold method which shows the superiority of the proposed method.

  1. A Decision Processing Algorithm for CDC Location Under Minimum Cost SCM Network

    Science.gov (United States)

    Park, N. K.; Kim, J. Y.; Choi, W. Y.; Tian, Z. M.; Kim, D. J.

    Location of CDC in the matter of network on Supply Chain is becoming on the high concern these days. Present status of methods on CDC has been mainly based on the calculation manually by the spread sheet to achieve the goal of minimum logistics cost. This study is focused on the development of new processing algorithm to overcome the limit of present methods, and examination of the propriety of this algorithm by case study. The algorithm suggested by this study is based on the principle of optimization on the directive GRAPH of SCM model and suggest the algorithm utilizing the traditionally introduced MST, shortest paths finding methods, etc. By the aftermath of this study, it helps to assess suitability of the present on-going SCM network and could be the criterion on the decision-making process for the optimal SCM network building-up for the demand prospect in the future.

  2. Recent results from CEC cost sharing research programme on LWR fuel behaviour under accident conditions

    International Nuclear Information System (INIS)

    Fairbairn, S.A.

    1983-01-01

    The present structure and intentions of the CEC sponsored cost sharing programme for LWR safety research are outlined. Detailed results are reported for two projects from this programme. The first project concerns experimental data on the thermohydraulic effects of flow diversion around ballooned fuel rods. Data are presented on single and two phase heat transfer in an electrically heated rod bundle. Detailed photographic data on droplet behaviour are also given. The second project is an investigation of the effects of zircaloy oxidation on rewetting during reflood. It is shown that as oxide thickness increases from 1μm to 76μm that rewet rates can increase by up to 40%. A systematic effect of oxidation on rewet temperatures is also noted. (author)

  3. Electricity to natural gas competition under customer-side technological change: a marginal cost pricing analysis

    International Nuclear Information System (INIS)

    Gulli', Francesco

    2004-01-01

    This paper aims at evaluating the impact of technological change (on the customer side of the meter) on the network energy industry (electricity and natural gas). The performances of the small gas fired power technologies and the electrical reversible heat pumps have improved remarkably over the last ten years, making possible (or more viable) two opposite technological trajectories: the fully gas-based system, based on the use of small CHP (combined heat and power generation) plants, which would involve a wide decentralisation of energy supply; the fully electric-based system, based on the use of reversible electric heat pumps, which would imply increasing centralisation of energy supply. The analysis described in this paper attempts to evaluate how these two kinds of technological solutions can impact on inter-service competition when input prices are ste equals to marginal costs of supply in each stage of the electricity and natural gas industries. For this purpose, unbundled prices over time and over space are simulated. In particular the paper shows that unbundling prices over space in not very important in affecting electricity to natural gas competition and that, when prices are set equal to long-run marginal costs, the fully electric-based solution (the reversible heat pump) is by far preferable to the fully gas-based solution (the CHP gas fired small power plant). In consequence, the first best outcome of the technological change would involve increasing large power generation and imported (from the utility grid) electricity consumption. Given this framework, we have to ask ourselves why operators, regulators and legislators are so optimistic about the development of the fully gas-based solutions. In this respect, the paper suggests that market distortions (such as market power, energy taxation and inefficient pricing regulation) might have give an ambiguous representation of the optimal technological trajectory, inducing to overestimate the social value

  4. Prohibition of thinking

    Directory of Open Access Journals (Sweden)

    Tomaž Sajovic

    2015-04-01

    Full Text Available Today’s society is governed – borrowing the terminology from Slavoj Žižek and his text Leninova izbira (Lenin’s choice, 2010 – by the unwritten denkverbot, or a “prohibition” of critical thinking. Its historical illustration is found in the notorious statement by Margaret Thatcher: “There is no alternative to neoliberalism.” The neoliberal economic and social contra revolution started in the 1960s at the department of economics of the university of chicago. Its most important proponent was american economist and winner of the noble prize in economics Milton Friedman. His programme was extremely conservative: “Firstly, the governments must do away with all the provisions and regulations that prevent accumulation of profit. Secondly, they must sell all the assets that are owned by them and could be managed with profit by corporations. And thirdly, the funding of welfare programmes must be decreased dramatically.” Milton friedman “carefully” concealed this completely inhumane ideology, which “matched the interests of big multinationals completely”, by formulating it through the academic “language of mathematics and science”, and thus “transformed” it into impartial economic science. Neoliberal managing of the economy was thus supposedly freed from human subjectivity and became “solely” the fulfilment of scientifically determined natural laws. It therefore became impossible to either doubt it or think critically about it. It is assumed that what enabled neoliberal ideology to parasitize science is the fact that under neoliberalism science itself became “ideology”. The Swiss-Canadian sociologist and philosopher Michel Freitag (1935– 2009, in his book le naufrage de l’université (1995, named it technoscience: “Science is not concerned with studying the world anymore, but with predicting the effects caused in the world by our practically justified interventions.” Technosciences focus on issues that

  5. The efficiency costs of separating carbon markets under the EU emissions trading scheme: A quantitative assessment for Germany

    International Nuclear Information System (INIS)

    Boehringer, Christoph; Hoffmann, Tim; Manrique-de-Lara-Penate, Casiano

    2006-01-01

    From 1 January 2005 onwards the European Union has launched the first large-scale international carbon emissions trading program. As the EU Emissions Trading Scheme (EU-ETS) covers only part of domestic carbon emissions, it implies a segmented environmental regulation scheme: Each EU Member State must specify additional domestic abatement policies for the sectors outside the EU-ETS in order to meet its emissions budget under the EU Burden Sharing Agreement. We highlight the generic problems of segmented carbon regulation in terms of information requirements for international carbon prices and domestic abatement costs of sectors outside the EU-ETS. Based on numerical simulations for Germany, we quantify the excess costs of segmented carbon regulation and conclude that inefficiencies can be much better explained by lobbying of influential EU-ETS sectors than by information problems. (Author)

  6. The Cost of Compliance: A CGE Assessment of Canada's Policy Options under the Kyoto Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Boehringer, Christoph (Univ. of Oldenburg, Dept. of Economics, D-26111 Oldenburg (Germany)); Rutherford, Thomas F. (ETH Zuerich, Center for Energy Policy and Economy, CH-8032 Zuerich (Switzerland))

    2008-07-01

    Canada is committed under the Kyoto Protocol to reduce greenhouse gas emissions between 2008 and 2012 to a level six percent below the 1990 reference value. To date, however, Canada's greenhouse gas emissions remain far above 1990 levels. Stringent short-term policy measures are needed if Canada is to meet this legally binding commitment. This paper uses a multi-region, multi-commodity static general equilibrium model to quantify the economic impacts of alternative compliance strategies for Canada in the context of climate policies undertaken by other Kyoto Parties. The numerical results confirm fears among Canadian policy makers of larger economic adjustment cost should Canada fulfill its Kyoto commitment solely through domestic action. Comprehensive use of flexible mechanisms - in particular the Clean Development Mechanism - could allow Canada to live up with its international climate policy commitment at a substantially lower economic cost

  7. Empirical Evidence on Time-Varying Hedging Effectiveness of Emissions Allowances under Departures from the Cost-of-Carry Theory

    Directory of Open Access Journals (Sweden)

    Kai Chang

    2013-01-01

    Full Text Available Under departures from the cost-of-carry theory, traded spot prices and conditional volatility disturbed from futures market have significant impacts on futures price of emissions allowances, and then we propose time-varying hedge ratios and hedging effectiveness estimation using ECM-GARCH model. Our empirical results show that conditional variance, conditional covariance, and their correlation between between spot and futures prices exhibit time-varying trends. Conditional volatility of spot prices, conditional volatility disturbed from futures market, and conditional correlation of market noises implied from spot and futures markets have significant effects on time-varying hedge ratios and hedging effectiveness. In the immature emissions allowances market, market participants optimize portfolio sizes between spot and futures assets using historical market information and then achieve higher risk reduction of assets portfolio revenues; accordingly, we can obtain better hedging effectiveness through time-varying hedge ratios with departures from the cost-of-carry theory.

  8. Assessing the environmental costs and benefits of plantations under future carbon pricing scenarios

    Science.gov (United States)

    Jackson, R. B.; Barrett, D. J.; Farley, K.; Guenther, A.; Jobbágy, E. G.; Murray, B. C.; McCarl, B. A.; Schlesinger, W. H.

    2004-12-01

    Carbon sequestration programs are gaining attention globally as a means to offset increasing fossil fuel emissions and atmospheric carbon dioxide concentrations. We are examining scenarios of C sequestration in four regions of the world: the U.S., South America, China, and Australia. The analysis uses economic models to predict where the plantations will be grown and then categorizes the other biogeochemical changes that will likely occur. The goals of the project include: 1) Evaluating the assumptions behind C sequestration programs for plantations, including the importance of rotation rates, a full accounting of carbon costs (e.g., planting and site preparation), and how the C would be stored and safeguarded. 2) Examining the scale of the process needed to make a substantial contribution to offset fossil fuel emissions (see below). The scenario we have chosen to evaluate is one that addresses the consequences of storing 1 PgC yr-1 for 50 years. 3) Determining and summarizing the evidence for other biogeochemical changes that will likely occur. Some of the factors to be evaluated include soil acidification, changes in water fluxes and water-table dynamics, nutrient losses, changes in soil fauna and biodiversity, volatile organic carbon emissions, and erosion. 4) A final goal of the project is to make concrete recommendations for where plantations may be the most beneficial in terms of C storage and other environmental benefits, such as the amelioration of salinity and groundwater upwelling in Australia.

  9. Joint cost of energy under an optimal economic policy of hybrid power systems subject to uncertainty

    International Nuclear Information System (INIS)

    Díaz, Guzmán; Planas, Estefanía; Andreu, Jon; Kortabarria, Iñigo

    2015-01-01

    Economical optimization of hybrid systems is usually performed by means of LCoE (levelized cost of energy) calculation. Previous works deal with the LCoE calculation of the whole hybrid system disregarding an important issue: the stochastic component of the system units must be jointly considered. This paper deals with this issue and proposes a new fast optimal policy that properly calculates the LCoE of a hybrid system and finds the lowest LCoE. This proposed policy also considers the implied competition among power sources when variability of gas and electricity prices are taken into account. Additionally, it presents a comparative between the LCoE of the hybrid system and its individual technologies of generation by means of a fast and robust algorithm based on vector logical computation. Numerical case analyses based on realistic data are presented that valuate the contribution of technologies in a hybrid power system to the joint LCoE. - Highlights: • We perform the LCoE calculation with the stochastic component jointly considered. • We propose a fast an optimal policy that minimizes the LCoE. • We compare the obtained LCoEs by means of a fast and robust algorithm. • We take into account the competition among gas prices and electricity prices

  10. Cost-utility analysis of antiviral use under pandemic influenza using a novel approach - linking pharmacology, epidemiology and heath economics.

    Science.gov (United States)

    Wu, D B C; Chaiyakunapruk, N; Pratoomsoot, C; Lee, K K C; Chong, H Y; Nelson, R E; Smith, P F; Kirkpatrick, C M; Kamal, M A; Nieforth, K; Dall, G; Toovey, S; Kong, D C M; Kamauu, A; Rayner, C R

    2018-03-01

    Simulation models are used widely in pharmacology, epidemiology and health economics (HEs). However, there have been no attempts to incorporate models from these disciplines into a single integrated model. Accordingly, we explored this linkage to evaluate the epidemiological and economic impact of oseltamivir dose optimisation in supporting pandemic influenza planning in the USA. An HE decision analytic model was linked to a pharmacokinetic/pharmacodynamics (PK/PD) - dynamic transmission model simulating the impact of pandemic influenza with low virulence and low transmissibility and, high virulence and high transmissibility. The cost-utility analysis was from the payer and societal perspectives, comparing oseltamivir 75 and 150 mg twice daily (BID) to no treatment over a 1-year time horizon. Model parameters were derived from published studies. Outcomes were measured as cost per quality-adjusted life year (QALY) gained. Sensitivity analyses were performed to examine the integrated model's robustness. Under both pandemic scenarios, compared to no treatment, the use of oseltamivir 75 or 150 mg BID led to a significant reduction of influenza episodes and influenza-related deaths, translating to substantial savings of QALYs. Overall drug costs were offset by the reduction of both direct and indirect costs, making these two interventions cost-saving from both perspectives. The results were sensitive to the proportion of inpatient presentation at the emergency visit and patients' quality of life. Integrating PK/PD-EPI/HE models is achievable. Whilst further refinement of this novel linkage model to more closely mimic the reality is needed, the current study has generated useful insights to support influenza pandemic planning.

  11. 75 FR 5452 - Regulations Under the Paul Wellstone and Pete Domenici Mental Health Parity and Addiction Equity...

    Science.gov (United States)

    2010-02-02

    ... Regulations Under the Paul Wellstone and Pete Domenici Mental Health Parity and Addiction Equity Act of 2008... and Pete Domenici Mental Health Parity and Addiction Equity Act of 2008 (MHPAEA). MHPAEA prohibits... collection techniques or other forms of information technology; and Estimates of capital or start-up costs...

  12. On the costs of self-interested economic behavior: how does stinginess get under the skin?

    Science.gov (United States)

    Dunn, Elizabeth W; Ashton-James, Claire E; Hanson, Margaret D; Aknin, Lara B

    2010-05-01

    The present study examined how financial decisions 'get under the skin'. Participants played an economic game in which they could donate some of their payment to another student. Affect was measured afterward and salivary cortisol was measured before and afterward. Participants who kept more money for themselves reported less positive affect, more negative affect, and more shame. Shame predicted higher levels of post-game cortisol, controlling for pre-game cortisol; stingy economic behavior therefore produced a significant indirect effect on cortisol via shame. Thus, shame and cortisol represent plausible emotional and biological pathways linking everyday decisions with downstream consequences for health.

  13. 50 CFR 401.4 - Activities prohibited.

    Science.gov (United States)

    2010-10-01

    ..., DEVELOPMENT AND ENHANCEMENT § 401.4 Activities prohibited. Law enforcement, public relations, harvesting, marketing and processing activities, construction of fisherman use facilities, and activities concerned with...

  14. Using Coevolution Genetic Algorithm with Pareto Principles to Solve Project Scheduling Problem under Duration and Cost Constraints

    Directory of Open Access Journals (Sweden)

    Alexandr Victorovich Budylskiy

    2014-06-01

    Full Text Available This article considers the multicriteria optimization approach using the modified genetic algorithm to solve the project-scheduling problem under duration and cost constraints. The work contains the list of choices for solving this problem. The multicriteria optimization approach is justified here. The study describes the Pareto principles, which are used in the modified genetic algorithm. We identify the mathematical model of the project-scheduling problem. We introduced the modified genetic algorithm, the ranking strategies, the elitism approaches. The article includes the example.

  15. A game-theoretic approach for calibration of low-cost magnetometers under noise uncertainty

    Science.gov (United States)

    Siddharth, S.; Ali, A. S.; El-Sheimy, N.; Goodall, C. L.; Syed, Z. F.

    2012-02-01

    Pedestrian heading estimation is a fundamental challenge in Global Navigation Satellite System (GNSS)-denied environments. Additionally, the heading observability considerably degrades in low-speed mode of operation (e.g. walking), making this problem even more challenging. The goal of this work is to improve the heading solution when hand-held personal/portable devices, such as cell phones, are used for positioning and to improve the heading estimation in GNSS-denied signal environments. Most smart phones are now equipped with self-contained, low cost, small size and power-efficient sensors, such as magnetometers, gyroscopes and accelerometers. A magnetometer needs calibration before it can be properly employed for navigation purposes. Magnetometers play an important role in absolute heading estimation and are embedded in many smart phones. Before the users navigate with the phone, a calibration is invoked to ensure an improved signal quality. This signal is used later in the heading estimation. In most of the magnetometer-calibration approaches, the motion modes are seldom described to achieve a robust calibration. Also, suitable calibration approaches fail to discuss the stopping criteria for calibration. In this paper, the following three topics are discussed in detail that are important to achieve proper magnetometer-calibration results and in turn the most robust heading solution for the user while taking care of the device misalignment with respect to the user: (a) game-theoretic concepts to attain better filter parameter tuning and robustness in noise uncertainty, (b) best maneuvers with focus on 3D and 2D motion modes and related challenges and (c) investigation of the calibration termination criteria leveraging the calibration robustness and efficiency.

  16. A game-theoretic approach for calibration of low-cost magnetometers under noise uncertainty

    International Nuclear Information System (INIS)

    Siddharth, S; Ali, A S; El-Sheimy, N; Goodall, C L; Syed, Z F

    2012-01-01

    Pedestrian heading estimation is a fundamental challenge in Global Navigation Satellite System (GNSS)-denied environments. Additionally, the heading observability considerably degrades in low-speed mode of operation (e.g. walking), making this problem even more challenging. The goal of this work is to improve the heading solution when hand-held personal/portable devices, such as cell phones, are used for positioning and to improve the heading estimation in GNSS-denied signal environments. Most smart phones are now equipped with self-contained, low cost, small size and power-efficient sensors, such as magnetometers, gyroscopes and accelerometers. A magnetometer needs calibration before it can be properly employed for navigation purposes. Magnetometers play an important role in absolute heading estimation and are embedded in many smart phones. Before the users navigate with the phone, a calibration is invoked to ensure an improved signal quality. This signal is used later in the heading estimation. In most of the magnetometer-calibration approaches, the motion modes are seldom described to achieve a robust calibration. Also, suitable calibration approaches fail to discuss the stopping criteria for calibration. In this paper, the following three topics are discussed in detail that are important to achieve proper magnetometer-calibration results and in turn the most robust heading solution for the user while taking care of the device misalignment with respect to the user: (a) game-theoretic concepts to attain better filter parameter tuning and robustness in noise uncertainty, (b) best maneuvers with focus on 3D and 2D motion modes and related challenges and (c) investigation of the calibration termination criteria leveraging the calibration robustness and efficiency. (paper)

  17. Respiratory ATP cost and benefit of arbuscular mycorrhizal symbiosis with Nicotiana tabacum at different growth stages and under salinity.

    Science.gov (United States)

    Del-Saz, Néstor Fernández; Romero-Munar, Antonia; Alonso, David; Aroca, Ricardo; Baraza, Elena; Flexas, Jaume; Ribas-Carbo, Miquel

    2017-11-01

    Growth and maintenance partly depend on both respiration and ATP production during oxidative phosphorylation in leaves. Under stress, ATP is needed to maintain the accumulated biomass. ATP production mostly proceeds from the cytochrome oxidase pathway (COP), while respiration via the alternative oxidase pathway (AOP) may decrease the production of ATP per oxygen consumed, especially under phosphorus (P) limitation and salinity conditions. Symbiosis with arbuscular mycorrhizal (AM) fungi is reputed by their positive effect on plant growth under stress at mature stages of colonization; however, fungal colonization may decrease plant growth at early stages. Thus, the present research is based on the hypothesis that AM fungus colonization will increase both foliar respiration and ATP production at mature stages of plant growth while decreasing them both at early stages. We used the oxygen-isotope-fractionation technique to study the in vivo respiratory activities and ATP production of the COP and AOP in AM and non-AM (NM) tobacco plants grown under P-limiting and saline conditions in sand at different growth stages (14, 28 and 49days). Our results suggest that AM symbiosis represents an ATP cost detrimental for shoot growth at early stages, whilst it represents a benefit on ATP allowing for faster rates of growth at mature stages, even under salinity conditions. Copyright © 2017 Elsevier GmbH. All rights reserved.

  18. 49 CFR 511.78 - Prohibited communications.

    Science.gov (United States)

    2010-10-01

    ... than a decisionmaker which is not served on all parties, (ii) Any oral communication other than a...) Prohibited ex parte communications. Any oral or written ex parte communication relative to the merits of a... circumstances shall be forwarded with the communication. (2) Prohibited oral ex parte communication. (i) If a...

  19. 31 CFR 560.207 - Prohibited investment.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Prohibited investment. 560.207... § 560.207 Prohibited investment. Except as otherwise authorized pursuant to this part, and... investment by a United States person in Iran or in property (including entities) owned or controlled by the...

  20. 24 CFR 891.832 - Prohibited relationships.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Prohibited relationships. 891.832 Section 891.832 Housing and Urban Development Regulations Relating to Housing and Urban Development... § 891.832 Prohibited relationships. Section 891.130 applies, except that in the mixed-finance program...

  1. 50 CFR 3.1 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Discrimination prohibited. 3.1 Section 3.1... PROVISIONS NONDISCRIMINATION-CONTRACTS, PERMITS, AND USE OF FACILITIES § 3.1 Discrimination prohibited. No..., be denied the benefits of, or be otherwise subjected to any form of discrimination or segregation...

  2. 49 CFR 374.101 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Discrimination prohibited. 374.101 Section 374.101... REGULATIONS Discrimination in Operations of Interstate Motor Common Carriers of Passengers § 374.101 Discrimination prohibited. No motor common carrier of passengers subject to 49 U.S.C. subtitle IV, part B shall...

  3. 45 CFR 1624.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Discrimination prohibited. 1624.4 Section 1624.4... AGAINST DISCRIMINATION ON THE BASIS OF DISABILITY § 1624.4 Discrimination prohibited. (a) No qualified... the benefits of, or otherwise be subjected to discrimination by any legal services program, directly...

  4. 28 CFR 35.149 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Discrimination prohibited. 35.149 Section... STATE AND LOCAL GOVERNMENT SERVICES Program Accessibility § 35.149 Discrimination prohibited. Except as... subjected to discrimination by any public entity. ...

  5. 18 CFR 8.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Discrimination prohibited. 8.3 Section 8.3 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION... LICENSED PROJECTS § 8.3 Discrimination prohibited. Every licensee maintaining recreation facilities for the...

  6. 29 CFR 502.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Discrimination prohibited. 502.3 Section 502.3 Labor... IMMIGRATION AND NATIONALITY ACT (SUSPENDED 6-29-2009) General Provisions § 502.3 Discrimination prohibited. (a... Department regulation promulgated pursuant to sec. 218 of the INA. (b) Allegations of discrimination against...

  7. 28 CFR 42.510 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Discrimination prohibited. 42.510 Section...-Implementation of Section 504 of the Rehabilitation Act of 1973 Employment § 42.510 Discrimination prohibited. (a) General. (1) No qualified handicapped person shall on the basis of handicap be subjected to discrimination...

  8. 29 CFR 500.9 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Discrimination prohibited. 500.9 Section 500.9 Labor... SEASONAL AGRICULTURAL WORKER PROTECTION General Provisions § 500.9 Discrimination prohibited. (a) It is a... Secretary alleging such discrimination. ...

  9. 45 CFR 1170.21 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 1170.21 Section 1170.21... ASSISTED PROGRAMS OR ACTIVITIES Employment Practices § 1170.21 Discrimination prohibited. (a) General. No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination in employment...

  10. 5 CFR 950.110 - Prohibited discrimination.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Prohibited discrimination. 950.110 Section 950.110 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE... PRIVATE VOLUNTARY ORGANIZATIONS General Provisions § 950.110 Prohibited discrimination. Discrimination for...

  11. 43 CFR 34.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Discrimination prohibited. 34.4 Section 34... DURING CONSTRUCTION AND OPERATION OF THE ALASKA NATURAL GAS TRANSPORTATION SYSTEM § 34.4 Discrimination... part applies. (b) Specific actions in which discrimination is prohibited. No person shall directly or...

  12. 24 CFR 1.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discrimination prohibited. 1.4... DEVELOPMENT-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 1.4 Discrimination prohibited. (a... excluded from participation in, be denied the benefits of, or be otherwise subjected to discrimination...

  13. 43 CFR 17.203 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Discrimination prohibited. 17.203 Section... Discrimination prohibited. (a) General. No qualified handicapped person shall, on the basis of handicap, be excluded from participation in, be denied the benefits of, or otherwise be subjected to discrimination...

  14. 45 CFR 1170.31 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Discrimination prohibited. 1170.31 Section 1170.31... ASSISTED PROGRAMS OR ACTIVITIES Accessibility § 1170.31 Discrimination prohibited. No qualified handicapped... denied the benefits of, be excluded from participation in, or otherwise be subjected to discrimination...

  15. 30 CFR 270.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Discrimination prohibited. 270.4 Section 270.4 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 270.4 Discrimination prohibited. No contract or subcontract to which...

  16. 13 CFR 120.476 - Prohibited financing.

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    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Prohibited financing. 120.476... Business Lending Companies (sblc) § 120.476 Prohibited financing. An SBLC may not make a loan to a small business that has received financing (or a commitment for financing) from an SBIC that is an Associate of...

  17. 10 CFR 430.61 - Prohibited acts.

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    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Prohibited acts. 430.61 Section 430.61 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY CONSERVATION PROGRAM FOR CONSUMER PRODUCTS Certification and... convenience of the user, the revised text is set forth as follows: § 430.61 Prohibited acts. (b) In accordance...

  18. 25 CFR 265.3 - Roads prohibited.

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    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Roads prohibited. 265.3 Section 265.3 Indians BUREAU OF... ON INDIAN RESERVATIONS § 265.3 Roads prohibited. (a) Within the boundaries of this officially... highways, roads, truck trails, work roads, and all other types of ways constructed to make possible the...

  19. 9 CFR 93.801 - Prohibitions.

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    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Prohibitions. 93.801 Section 93.801 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... CONVEYANCE AND SHIPPING CONTAINERS Elephants, Hippopotami, Rhinoceroses, and Tapirs § 93.801 Prohibitions...

  20. 12 CFR 703.16 - Prohibited investments.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Prohibited investments. 703.16 Section 703.16 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS INVESTMENT AND DEPOSIT ACTIVITIES § 703.16 Prohibited investments. (a) Derivatives. A Federal credit union may...

  1. An interval-based possibilistic programming method for waste management with cost minimization and environmental-impact abatement under uncertainty.

    Science.gov (United States)

    Li, Y P; Huang, G H

    2010-09-15

    Considerable public concerns have been raised in the past decades since a large amount of pollutant emissions from municipal solid waste (MSW) disposal of processes pose risks on surrounding environment and human health. Moreover, in MSW management, various uncertainties exist in the related costs, impact factors and objectives, which can affect the optimization processes and the decision schemes generated. In this study, an interval-based possibilistic programming (IBPP) method is developed for planning the MSW management with minimized system cost and environmental impact under uncertainty. The developed method can deal with uncertainties expressed as interval values and fuzzy sets in the left- and right-hand sides of constraints and objective function. An interactive algorithm is provided for solving the IBPP problem, which does not lead to more complicated intermediate submodels and has a relatively low computational requirement. The developed model is applied to a case study of planning a MSW management system, where mixed integer linear programming (MILP) technique is introduced into the IBPP framework to facilitate dynamic analysis for decisions of timing, sizing and siting in terms of capacity expansion for waste-management facilities. Three cases based on different waste-management policies are examined. The results obtained indicate that inclusion of environmental impacts in the optimization model can change the traditional waste-allocation pattern merely based on the economic-oriented planning approach. The results obtained can help identify desired alternatives for managing MSW, which has advantages in providing compromised schemes under an integrated consideration of economic efficiency and environmental impact under uncertainty. Copyright 2010 Elsevier B.V. All rights reserved.

  2. [Cost-effectiveness analysis of schizophrenic patient care settings: impact of an atypical antipsychotic under long-acting injection formulation].

    Science.gov (United States)

    Llorca, P M; Miadi-Fargier, H; Lançon, C; Jasso Mosqueda, G; Casadebaig, F; Philippe, A; Guillon, P; Mehnert, A; Omnès, L F; Chicoye, A; Durand-Zaleski, I

    2005-01-01

    patient for two years were taken into account. The results show that in two years, LA risperidone is more effective than the two other antipsychotics. After 2 years, the rate of patients treated successfully is 82,7% for LA risperidone, 74,8% for olanzapine and 57,3% for haloperidol depot. The 2 year-cost per patient treated by LA risperidone is 14,055 Euro. This cost is 14,351 Euro and 17,203 Euro respectively for the strategies olanzapine and haloperidol depot. The cost-efficacy ratios per patient successfully treated are 16,995 Euro for the strategy LA risperidone, 19,186 Euro for olanzapine and 30,023 Euro for haloperidol depot. LA risperidone is a dominant strategy compared with both olanzapine and haloperidol depot. Scenario 1 shows that LA risperidone strategy remains the most effective. Indeed, this strategy allows a response increase of 3,5% regarding olanzapine strategy and of 21% regarding haloperidol depot strategy. Under the hypothesis tested in scenario 1, LA risperidone is a partial dominant strategy against olanzapine and a total dominant strategy against haloperidol depot. In scenario 2, as efficacy is improved for haloperidol decanoate (61,10%), a decrease of 1,763 Euro in the cost per patient treated is observed for this strategy. Cost per patient treated successfully and efficacy for LA risperidone and olanzapine are the same than in the base case. LA risperidone is a total dominant strategy against olanzapine and haloperidol decanoate. In scenario 3, the rate of patients treated successfully at 2 years is 88,6% for LA risperidone with a cost per patient of 12,347 Euro. LA risperidone is dominant against olanzapine and haloperidol depot. The schizophrenia is a relatively frequent disease. (ABSTRACT TRUNCATED)

  3. Comprehensive Assessment of New Proppants for Hydraulic Fracturing Utilization under the Consideration of Cost, Environmental & Health Impacts

    Science.gov (United States)

    Adebakin, Mariam Abiodun

    The advancement and increased practice of hydraulic fracturing, a process which involves the drilling of a well and the injection of fracture fluid (water, proppant and various chemicals) under high pressure to stimulate the production of oil and gas, has gradually gained public attention over the past years. This is because of its effectiveness in booming the nation's economy as well as the adverse effects in terms of risks this process poses to all forms of life. Several speculations have been raised about the choice of proppant used as a contributory factor to the risks hydraulic fracturing poses. Frac sand is the most widely used proppant in several wells in the United States but several health and environmental concerns has been raised on its short and long term use. It is therefore imperative to examine the impacts (health and environmental) as well as cost implication, if any, in selecting the most appropriate proppant in other to reduce and or completely eliminate its effect on humans and other forms of life. This study aims to compare other proppants (resin-coated sand and ceramic) with frac sand, focusing on cost, environmental and health implications when used. This study found that sand is the cheapest and most available proppant in terms of production cost compared to resin coated sand and ceramic proppant. However, sand cannot be used in deep wells as it is subjected to more stress leading to its disintegration and crushing in the well which eventually blocks the fissures created and the subsequent flow of oil and gas. In terms of health and environmental impacts, sand should be discouraged as it generates crystalline silica dust known to be injurious if inhaled.

  4. Cost-optimal power system extension under flow-based market coupling and high shares of photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Hagspiel, Simeon; Jaegemann, Cosima; Lindenberger, Dietmar [Koeln Univ. (Germany). Inst. of Energy Economics; Cherevatskiy, Stanislav; Troester, Eckehard; Brown, Tom [Energynautics GmbH, Langen (Germany)

    2012-07-01

    Electricity market models, implemented as dynamic programming problems, have been applied widely to identify possible pathways towards a cost-optimal and low carbon electricity system. However, the joint optimization of generation and transmission remains challenging, mainly due to the fact that different characteristics and rules apply to commercial and physical exchanges of electricity in meshed networks. This paper presents a methodology that allows to optimize power generation and transmission infrastructures jointly through an iterative approach based on power transfer distribution factors (PTDFs). As PTDFs are linear representations of the physical load flow equations, they can be implemented in a linear programming environment suitable for large scale problems such as the European power system. The algorithm iteratively updates PTDFs when grid infrastructures are modified due to cost-optimal extension and thus yields an optimal solution with a consistent representation of physical load flows. The method is demonstrated on a simplified three-node model where it is found to be stable and convergent. It is then scaled to the European level in order to find the optimal power system infrastructure development under the prescription of strongly decreasing CO{sub 2} emissions in Europe until 2050 with a specific focus on photovoltaic (PV) power. (orig.)

  5. An improved, low-cost, hydroponic system for growing Arabidopsis and other plant species under aseptic conditions.

    Science.gov (United States)

    Alatorre-Cobos, Fulgencio; Calderón-Vázquez, Carlos; Ibarra-Laclette, Enrique; Yong-Villalobos, Lenin; Pérez-Torres, Claudia-Anahí; Oropeza-Aburto, Araceli; Méndez-Bravo, Alfonso; González-Morales, Sandra-Isabel; Gutiérrez-Alanís, Dolores; Chacón-López, Alejandra; Peña-Ocaña, Betsy-Anaid; Herrera-Estrella, Luis

    2014-03-21

    Hydroponics is a plant growth system that provides a more precise control of growth media composition. Several hydroponic systems have been reported for Arabidopsis and other model plants. The ease of system set up, cost of the growth system and flexibility to characterize and harvest plant material are features continually improved in new hydroponic system reported. We developed a hydroponic culture system for Arabidopsis and other model plants. This low cost, proficient, and novel system is based on recyclable and sterilizable plastic containers, which are readily available from local suppliers. Our system allows a large-scale manipulation of seedlings. It adapts to different growing treatments and has an extended growth window until adult plants are established. The novel seed-holder also facilitates the transfer and harvest of seedlings. Here we report the use of our hydroponic system to analyze transcriptomic responses of Arabidopsis to nutriment availability and plant/pathogen interactions. The efficiency and functionality of our proposed hydroponic system is demonstrated in nutrient deficiency and pathogenesis experiments. Hydroponically grown Arabidopsis seedlings under long-time inorganic phosphate (Pi) deficiency showed typical changes in root architecture and high expression of marker genes involved in signaling and Pi recycling. Genome-wide transcriptional analysis of gene expression of Arabidopsis roots depleted of Pi by short time periods indicates that genes related to general stress are up-regulated before those specific to Pi signaling and metabolism. Our hydroponic system also proved useful for conducting pathogenesis essays, revealing early transcriptional activation of pathogenesis-related genes.

  6. The differential impact of low-carbon technologies on climate change mitigation cost under a range of socioeconomic and climate policy scenarios

    International Nuclear Information System (INIS)

    Barron, Robert; McJeon, Haewon

    2015-01-01

    This paper considers the effect of several key parameters of low carbon energy technologies on the cost of abatement. A methodology for determining the minimum level of performance required for a parameter to have a statistically significant impact on CO 2 abatement cost is developed and used to evaluate the impact of eight key parameters of low carbon energy supply technologies on the cost of CO 2 abatement. The capital cost of nuclear technology is found to have the greatest impact of the parameters studied. The cost of biomass and CCS technologies also have impacts, while their efficiencies have little, if any. Sensitivity analysis of the results with respect to population, GDP, and CO 2 emission constraint show that the minimum performance level and impact of nuclear technologies is consistent across the socioeconomic scenarios studied, while the other technology parameters show different performance under higher population, lower GDP scenarios. Solar technology was found to have a small impact, and then only at very low costs. These results indicate that the cost of nuclear is the single most important driver of abatement cost, and that trading efficiency for cost may make biomass and CCS technologies more competitive. - Highlights: • The impact of low carbon energy technology on abatement cost is considered. • Nuclear has the largest impact among technologies considered. • Cost has higher impact than efficiency for biomass technologies. • Biomass technologies generally have larger impacts than carbon capture. • Biomass technologies are more valuable in low GDP, high population scenarios

  7. Technical development of cost-efficient installation of power distribution cables under pavements. Haiden chichuka ni okeru doboku kensetsu gorika gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Kokusho, Koji; Kataoka, Tetsuyuki; Tanaka, Yasuyuki; Yoshida, Yasuo; Ikemi, Motoyoshi; Suzuki, Koichi; Kitano, Koichi; Kobayashi, Seiichi; Kanazu, Tsutomu; Komada, Hiroya.

    1987-12-01

    Various latest technical developments were surveyed for the cost-effective installation of power distribution cables under pavements, and their applicabilities were demonstrated with the evaluation of their cost-reduction effects. Cables in conventional vinyl protection tubes could be buried only 30cm under pavements, and in such case, the cost was reduced to 51% of those of conventional methods. As the results of soil tests, excavated soil over 80% was reusable through coarse screening. Underground radar technique to explore buried pipes from the surface was detectable several pipes buried 1.5-2.0m underground, although some problems in precision were found. The improvement of reinforced concrete man-hole structures to minimize the volume of excavated soil indicated the cost reduction of nearly 20%. The application of these techniques to the installation of cables was expected to ultimately halve the total civil engineering cost. 21 refs., 130 figs., 46 tabs.

  8. A deterministic evaluation of heat stress mitigation and feed cost under climate change within the smallholder dairy sector.

    Science.gov (United States)

    York, L; Heffernan, C; Rymer, C; Panda, N

    2017-05-01

    In the global South, dairying is often promoted as a means of poverty alleviation. Yet, under conditions of climate warming, little is known regarding the ability of small-scale dairy producers to maintain production and/or the robustness of possible adaptation options in meeting the challenges presented, particularly heat stress. The authors created a simple, deterministic model to explore the influence of breed and heat stress relief options on smallholder dairy farmers in Odisha, India. Breeds included indigenous Indian (non-descript), low-grade Jersey crossbreed and high-grade Jersey crossbreed. Relief strategies included providing shade, fanning and bathing. The impact of predicted critical global climate parameters, a 2°C and 4°C temperature rise were explored. A feed price scenario was modelled to illustrate the importance of feed in impact estimation. Feed costs were increased by 10% to 30%. Across the simulations, high-grade Jersey crossbreeds maintained higher milk yields, despite being the most sensitive to the negative effects of temperature. Low-capital relief strategies were the most effective at reducing heat stress impacts on household income. However, as feed costs increased the lower-grade Jersey crossbreed became the most profitable breed. The high-grade Jersey crossbreed was only marginally (4.64%) more profitable than the indigenous breed. The results demonstrate the importance of understanding the factors and practical trade-offs that underpin adaptation. The model also highlights the need for hot-climate dairying projects and programmes to consider animal genetic resources alongside environmentally sustainable adaptation measures for greatest poverty impact.

  9. Cost-Risk Trade-off of Solar Radiation Management and Mitigation under Probabilistic Information on Climate Sensitivity

    Science.gov (United States)

    Khabbazan, Mohammad Mohammadi; Roshan, Elnaz; Held, Hermann

    2017-04-01

    In principle solar radiation management (SRM) offers an option to ameliorate anthropogenic temperature rise. However we cannot expect it to simultaneously compensate for anthropogenic changes in further climate variables in a perfect manner. Here, we ask to what extent a proponent of the 2°C-temperature target would apply SRM in conjunction with mitigation in view of global or regional disparities in precipitation changes. We apply cost-risk analysis (CRA), which is a decision analytic framework that makes a trade-off between the expected welfare-loss from climate policy costs and the climate risks from transgressing a climate target. Here, in both global-scale and 'Giorgi'-regional-scale analyses, we evaluate the optimal mixture of SRM and mitigation under probabilistic information about climate sensitivity. To do so, we generalize CRA for the sake of including not only temperature risk, but also globally aggregated and regionally disaggregated precipitation risks. Social welfare is maximized for the following three valuation scenarios: temperature-risk-only, precipitation-risk-only, and equally weighted both-risks. For now, the Giorgi regions are treated by equal weight. We find that for regionally differentiated precipitation targets, the usage of SRM will be comparably more restricted. In the course of time, a cooling of up to 1.3°C can be attributed to SRM for the latter scenario and for a median climate sensitivity of 3°C (for a global target only, this number reduces by 0.5°C). Our results indicate that although SRM would almost completely substitute for mitigation in the globally aggregated analysis, it only saves 70% to 75% of the welfare-loss compared to a purely mitigation-based analysis (from economic costs and climate risks, approximately 4% in terms of BGE) when considering regional precipitation risks in precipitation-risk-only and both-risks scenarios. It remains to be shown how the inclusion of further risks or different regional weights would

  10. Report: Ozone Transport Commission Incurred Costs Under EPA Assistance Agreements XA98379901, OT83098301, XA97318101, and OT83264901

    Science.gov (United States)

    Report #2007-4-00068, July 31, 2007. We questioned $2,723,706 of the $9,042,706 in reported outlays because the recipient claimed unallowable outlays for contractual services, indirect costs, and in-kind costs.

  11. Purchasing motors under consideration of full-cost pricing; Beschaffung von Motoren unter der Vollkostenbetrachtung (inklusive Permanentmagneterregte-Synchronmotoren) - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Mauchle, P. [Schnyder Ingenieure AG, Huenenberg (Switzerland); Ritz, Ch. [Schnyder Ingenieure AG, Steg (Switzerland)

    2007-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at how full-cost pricing should be considered when purchasing electric motors. The authors consider it essential that the overall life-cycle costs are carefully considered. This also guarantees economical operation and enables users to avoid unexpected costs throughout the service life of the motor. The aim of this project was to provide industrial companies with suitable tools for calculating the overall life-cycle costs of motors at the time of their acquisition. These tools take the form of a sample 'Call for Tender' for motors along with software for calculating life-cycle costs. The factors involved, such as investment, installation costs, energy and environmental costs as well as operational, maintenance and disposal costs are examined.

  12. 34 CFR 76.532 - Use of funds for religion prohibited.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Use of funds for religion prohibited. 76.532 Section 76.532 Education Office of the Secretary, Department of Education STATE-ADMINISTERED PROGRAMS What Conditions Must Be Met by the State and Its Subgrantees? Allowable Costs § 76.532 Use of funds for religion...

  13. Prohibited Contaminants in Dietary Supplements.

    Science.gov (United States)

    Mathews, Neilson M

    With the increasing use of unregulated dietary supplements, athletes are at continued risk from adverse medical events and inadvertent doping. A review of Clinical Key, MEDLINE, and PubMed databases from 2012 to 2017 was performed using search terms, including dietary supplement, contamination, doping in athletes, inadvertent doping, and prohibited substances. The references of pertinent articles were reviewed for other relevant sources. Clinical review. Level 3. Poor manufacturing processes and intentional contamination with many banned substances continue to occur in dietary supplements sold in the United States. Certain sectors, such as weight loss and muscle-building supplements, pose a greater threat because they are more likely to be contaminated. Athletes will continue to be at risk for adverse events and failed doping tests due to contaminated dietary supplements until legislation changes how they are regulated. In the interim, there are several steps that can be taken to mitigate this risk, including improved education of medical staff and athletes and use of third party-certified products.

  14. 49 CFR 241.13 - Prohibition against track owner's requiring or permitting use of its line for a railroad...

    Science.gov (United States)

    2010-10-01

    ... OF UNITED STATES RAIL OPERATIONS § 241.13 Prohibition against track owner's requiring or permitting... for compliance with this section and subject to civil penalties under § 241.15. A common carrier by...

  15. The differential impact of low-carbon technologies on climate change mitigation cost under a range of socioeconomic and climate policy scenarios.

    Energy Technology Data Exchange (ETDEWEB)

    Barron, Robert W.; McJeon, Haewon C.

    2015-05-01

    This paper considers the effect of several key parameters of low carbon energy technologies on the cost of abatement. A methodology for determining the minimum level of performance required for a parameter to have a statistically significant impact on CO2 abatement cost is developed and used to evaluate the impact of eight key parameters of low carbon energy supply technologies on the cost of CO2 abatement. The capital cost of nuclear technology is found to have the greatest impact of the parameters studied. The cost of biomass and CCS technologies also have impacts, while their efficiencies have little, if any. Sensitivity analysis of the results with respect to population, GDP, and CO2 emission constraint show that the minimum performance level and impact of nuclear technologies is consistent across the socioeconomic scenarios studied, while the other technology parameters show different performance under higher population, lower GDP scenarios. Solar technology was found to have a small impact, and then only at very low costs. These results indicate that the cost of nuclear is the single most important driver of abatement cost, and that trading efficiency for cost may make biomass and CCS technologies more competitive.

  16. Profile of medical care costs in patients with amyotrophic lateral sclerosis in the Medicare programme and under commercial insurance.

    Science.gov (United States)

    Meng, Lisa; Bian, Amy; Jordan, Scott; Wolff, Andrew; Shefner, Jeremy M; Andrews, Jinsy

    2018-02-01

    To determine amyotrophic lateral sclerosis (ALS)-associated costs incurred by patients covered by Medicare and/or commercial insurance before, during and after diagnosis and provide cost details. Costs were calculated from the Medicare Standard Analytical File 5% sample claims data from Parts A and B from 2009, 2010 and 2011 for ALS Medicare patients aged ≥70 years (monthly costs) and ≥65 years (costs associated with disability milestones). Commercial insurance patients aged 18-63 years were selected based on the data provided in the Coordination of Benefits field from Truven MarketScan® in 2008-2010. Monthly costs increased nine months before diagnosis, peaked during the index month (Medicare: $10,398; commercial: $9354) and decreased but remained high post-index. Costs generally shifted from outpatient to inpatient and private nursing after diagnosis; prescriptions and durable medical equipment costs were much higher for commercial patients post-diagnosis. Patients appeared to progress to disability milestones more rapidly as their disease progressed in severity (14.4 months to non-invasive ventilation [NIV] vs. 16.6 months to hospice), and their costs increased accordingly (NIV: $58,973 vs. hospice: $76,179). For newly diagnosed ALS patients in the U.S., medical costs are substantial and increase rapidly and substantially with each disability milestone.

  17. Scaling and long-range dependence in option pricing V: Multiscaling hedging and implied volatility smiles under the fractional Black-Scholes model with transaction costs

    Science.gov (United States)

    Wang, Xiao-Tian

    2011-05-01

    This paper deals with the problem of discrete time option pricing using the fractional Black-Scholes model with transaction costs. Through the ‘anchoring and adjustment’ argument in a discrete time setting, a European call option pricing formula is obtained. The minimal price of an option under transaction costs is obtained. In addition, the relation between scaling and implied volatility smiles is discussed.

  18. Pot politics: marijuana and the costs of prohibition

    National Research Council Canada - National Science Library

    Earleywine, Mitchell

    2007-01-01

    ... so that the responsible use of marijuana by an adult will no longer be a criminal or civil offense. I've participated in long, intellectual retreats on mountaintops, suffered through multihour conference calls, participated in moot courts and legislatures, and attended dozens of conferences and symposiums all directed toward ending marijuana prohibi...

  19. 10 CFR 32.55 - Same: Quality assurance; prohibition of transfer.

    Science.gov (United States)

    2010-01-01

    ...; prohibition of transfer. (a) Each person licensed under § 32.53 shall visually inspect each device and shall... promethium-147. (b) Each person licensed under § 32.53 shall take a random sample of the size required by the... subject each unit in the sample to the following tests: (1) Each device shall be immersed in 30 inches of...

  20. The Prohibition of Medicinal Claims: Food in Fact But Medicinal Product in Law?

    NARCIS (Netherlands)

    Bremmers, H.J.; Meulen, van der B.M.J.; Waarts, Y.R.

    2015-01-01

    Under EU medicinal law, any substance or combination of substances presented as having properties for treating or preventing disease in human beings is a medicinal product by virtue of its presentation. Under EU food law it is prohibited to attribute to any food the property of preventing, treating

  1. The Effects of Hypobaric Hypoxia on Erythropoiesis, Maximal Oxygen Uptake and Energy Cost of Exercise Under Normoxia in Elite Biathletes

    Directory of Open Access Journals (Sweden)

    Milosz Czuba

    2014-12-01

    Full Text Available The aim of the present study was to evaluate the effects of 3 weeks altitude training according to the HiHiLo (live high-base train high-interval train low procedure as described by Chapman et al. (1998, on erythropoiesis, maximal oxygen uptake and energy cost of exercise under normoxia in elite biathletes. Fifteen male elite biathletes randomly divided into an experimental (H group (n = 7; age 27.1 ± 4.6 years; maximal oxygen uptake (VO2max 66.9 ± 3.3 ml·kg–1·min–1; body height (BH 1.81 ± 0.06 m; body mass (BM 73.1 ± 5.4kg, and a control (C group (n = 8; age 23.2 ± 0.9 years; VO2max 68.2 ± 4.1 ml·kg–1·min–1; BH 1.75 ± 0.03 m; BM 63.1 ± 1.5 kg took part in the study. The H group stayed for 3 weeks at an altitude of 2015 m and performed endurance training on skis four times per week at 3000 m. Additionally, the training protocol included three high-intensity interval sessions at an altitude of 1000 m. The C group followed the same training protocol with skirollers in normoxia at an altitude of 600 m. The HiHiLo protocol applied in our study did not change VO2max or maximal workload (WRmax significantly during the incremental treadmill test in group H. However, the energy cost for selected submaximal workloads in group H was significantly (p < 0.01 reduced compared to group C (-5.7%, -4.4%, -6% vs. -3.5%, -2.1%, -2.4%. Also a significant (p < 0.001 increase in serum EPO levels during the first two weeks of HiHiLo training at 2015 m was observed, associated with a significant (p < 0.05 increase in hemoglobin mass, number of erythrocytes, hematocrit value and percent of reticulocytes compared with initial values (by 6.4%, 5%, 4.6% and 16,6%, respectively. In group C, changes in these variables were not observed. These positive changes observed in our study led to a conclusion that the HiHiLo training method could improve endurance in normoxia, since most of the biathlon competitions are performed at submaximal intensities.

  2. Ground-penetrating radar investigation of St. Leonard's Crypt under the Wawel Cathedral (Cracow, Poland) - COST Action TU1208

    Science.gov (United States)

    Benedetto, Andrea; Pajewski, Lara; Dimitriadis, Klisthenis; Avlonitou, Pepi; Konstantakis, Yannis; Musiela, Małgorzata; Mitka, Bartosz; Lambot, Sébastien; Żakowska, Lidia

    2016-04-01

    The Wawel ensemble, including the Royal Castle, the Wawel Cathedral and other monuments, is perched on top of the Wawel hill immediately south of the Cracow Old Town, and is by far the most important collection of buildings in Poland. St. Leonard's Crypt is located under the Wawel Cathedral of St Stanislaus BM and St Wenceslaus M. It was built in the years 1090-1117 and was the western crypt of the pre-existing Romanesque Wawel Cathedral, so-called Hermanowska. Pope John Paul II said his first Mass on the altar of St. Leonard's Crypt on November 2, 1946, one day after his priestly ordination. The interior of the crypt is divided by eight columns into three naves with vaulted ceiling and ended with one apse. The tomb of Bishop Maurus, who died in 1118, is in the middle of the crypt under the floor; an inscription "+ MAVRVS EPC MCXVIII +" indicates the burial place and was made in 1938 after the completion of archaeological works which resulted in the discovery of this tomb. Moreover, the crypt hosts the tombs of six Polish kings and heroes: Michał Korybut Wiśniowiecki (King of the Polish-Lithuanian Commonwealth), Jan III Sobieski (King of the Polish-Lithuanian Commonwealth and Commander at the Battle of Vienna), Maria Kazimiera (Queen of the Polish-Lithuanian Commonwealth and consort to Jan III Sobieski), Józef Poniatowski (Prince of Poland and Marshal of France), Tadeusz Kościuszko (Polish general, revolutionary and a Brigadier General in the American Revolutionary War) and Władysław Sikorski (Prime Minister of the Polish Government in Exile and Commander-in-Chief of the Polish Armed Forces). The adjacent six crypts and corridors host the tombs of the other Polish kings, from Sigismund the Old to Augustus II the Strong, their families and several Polish heroes. In May 2015, the COST (European COoperation in Science and Technology) Action TU1208 "Civil engineering applications of Ground Penetrating Radar" organised and offered a Training School (TS) on the

  3. [Cost recovery for the treatment of retinal and vitreal diseases by pars plana vitrectomy under the German DRG system].

    Science.gov (United States)

    Framme, C; Franz, D; Mrosek, S; Helbig, H

    2007-10-01

    Since 2004 inpatient health care in Germany is paid according to calculated DRGs. Only a few university hospitals participated in distinct cost calculations of clinical treatment. It was the aim of this study to check the cost recovery at a University Eye Hospital for the surgical treatment of retinal and vitreal diseases by pars plana vitrectomy (ppV), which are included in DRGs C03Z and C17Z. The performance data for both DRGs were collected for the years 2005 and 2006 using the E1 sheets according to section 21 KHEntG. The mean duration of all procedures was collected by data from the internal controlling. Costs for single operations were calculated from fixed and variable costs for the operation theatre and the ward including costs for personnel and material. In the 2-year period of 4,721 inpatient procedures 1,307 ppVs were performed. Each ppV had fixed surgical costs of 130.60 EUR; personnel costs varied between 575 EUR (C03Z; including cataract surgery; mean OP duration: 85 min) and 510 EUR (C17Z; no cataract surgery; mean OP duration: 73 min) at a proportion between general anaesthesia and local anaesthesia of 80/20. For a pure ppV material costs were 255 EUR. Additional adjuncts such as an encircling band, perfluorcarbon, ICG, tPA, gas and silicon oil or cataract surgery led to extra costs between 51 EUR and 250 EUR per adjunct und were used in 56% (C03Z) and 74.5% (C17Z) of all procedures. Costs for hospitalisation were about 1765 EUR at a mean residence time of 6.5 days. Thus, the overall costs of a pure basic ppV amounted to 2975 EUR (C03Z) and 2661 EUR (C17Z). In consideration of the current relative DRG weights of 1.08 and 0.957 and a current base rate of 2787.19 EUR in Bavaria, cost recovery is only given for basic ppV but not for complex ppVs having higher material and personnel costs. Additionally, the costs for multiple surgeries as occur in 5.9% of cases are not compensated by the DRG system. The reimbursement for inpatient ppVs in a University

  4. Refinement of motion correction strategies for lower-cost CT for under-resourced regions of the world

    Science.gov (United States)

    Wells, Jered R.; Segars, W. Paul; Kigongo, Christopher J. N.; Dobbins, James T., III

    2011-03-01

    This paper describes a recently developed post-acquisition motion correction strategy for application to lower-cost computed tomography (LCCT) for under-resourced regions of the world. Increased awareness regarding global health and its challenges has encouraged the development of more affordable healthcare options for underserved people worldwide. In regions such as sub-Saharan Africa, intermediate level medical facilities may serve millions with inadequate or antiquated equipment due to financial limitations. In response, the authors have proposed a LCCT design which utilizes a standard chest x-ray examination room with a digital flat panel detector (FPD). The patient rotates on a motorized stage between the fixed cone-beam source and FPD, and images are reconstructed using a Feldkamp algorithm for cone-beam scanning. One of the most important proofs-of-concept in determining the feasibility of this system is the successful correction of undesirable motion. A 3D motion correction algorithm was developed in order to correct for potential patient motion, stage instabilities and detector misalignments which can all lead to motion artifacts in reconstructed images. Motion will be monitored by the radiographic position of fiducial markers to correct for rigid body motion in three dimensions. Based on simulation studies, projection images corrupted by motion were re-registered with average errors of 0.080 mm, 0.32 mm and 0.050 mm in the horizontal, vertical and depth dimensions, respectively. The overall absence of motion artifacts in motion-corrected reconstructions indicates that reasonable amounts of motion may be corrected using this novel technique without significant loss of image quality.

  5. The Legitimacy of Prohibiting Euthanasia

    Directory of Open Access Journals (Sweden)

    Gildenhuys, Peter

    2015-10-01

    Full Text Available ohn Arras argues against the legalization of physician- assisted suicide and active euthanasia on the basis of social costs that he anticipates will result from legalization. Arras believes that the legalization of highly restricted physician-assisted suicide will result in the legalization of active euthanasia without special restrictions, a prediction I grant for the sake of argument. Arras further anticipates that the practices of physician-assisted suicide and euthanasia will be abused, so that many patients who engage in these practices will lose out as a result. He refers to these losses as social costs to legalization. But the social costs at play in typical public policy debates are borne by individuals other than the agent who engages in the controversial activity, specifically by people who cannot be held responsible for enduring those costs. Even if plausible interpretations of Arras’ predictions about the abuse of the practice are granted, legalization of physician-assisted suicide or euthanasia brings no social costs of this latter sort. For this reason, and also because a ban on euthanasia is unfair to those who would profit from it, the losses in utility brought about by legalization would have to be very great to justify a ban.

  6. Cost Effectiveness of Genotype-Guided Warfarin Dosing in Patients with Mechanical Heart Valve Replacement Under the Fee-for-Service System.

    Science.gov (United States)

    Kim, Dong-Jin; Kim, Ho-Sook; Oh, Minkyung; Kim, Eun-Young; Shin, Jae-Gook

    2017-10-01

    Although studies assessing the cost effectiveness of genotype-guided warfarin dosing for the management of atrial fibrillation, deep vein thrombosis, and pulmonary embolism have been reported, no publications have addressed genotype-guided warfarin therapy in mechanical heart valve replacement (MHVR) patients or genotype-guided warfarin therapy under the fee-for-service (FFS) insurance system. The aim of this study was to evaluate the cost effectiveness of genotype-guided warfarin dosing in patients with MHVR under the FFS system from the Korea healthcare sector perspective. A decision-analytic Markov model was developed to evaluate the cost effectiveness of genotype-guided warfarin dosing compared with standard dosing. Estimates of clinical adverse event rates and health state utilities were derived from the published literature. The outcome measure was the incremental cost-effectiveness ratio (ICER) per quality-adjusted life-year (QALY). One-way and probabilistic sensitivity analyses were performed to explore the range of plausible results. In a base-case analysis, genotype-guided warfarin dosing was associated with marginally higher QALYs than standard warfarin dosing (6.088 vs. 6.083, respectively), at a slightly higher cost (US$6.8) (year 2016 values). The ICER was US$1356.2 per QALY gained. In probabilistic sensitivity analysis, there was an 82.7% probability that genotype-guided dosing was dominant compared with standard dosing, and a 99.8% probability that it was cost effective at a willingness-to-pay threshold of US$50,000 per QALY gained. Compared with only standard warfarin therapy, genotype-guided warfarin dosing was cost effective in MHVR patients under the FFS insurance system.

  7. Strategic research on the sustainable development cost of manufacturing industry under the background of carbon allowance and trade policy

    Science.gov (United States)

    Ma, Zhongmin; Cheng, Mengting; Wang, Mei

    2017-08-01

    The important subjects of energy consumption and carbon emission are manufacturing enterprises, with the deepening of international cooperation, and the implementation of carbon limit and trade policy, costs of manufacturing industry will rise sharply. How can the manufacturing industry survive in this reform, and it has to be a problem that the managers of the manufacturing industry need to solve. This paper analyses sustainable development cost connotation and value basis on the basis of sustainable development concept, discusses the influence of carbon allowance and trade policy for cost strategy of manufacturing industry, thinks that manufacturing industry should highlight social responsibility and realize maximization of social value, implement cost strategy the sustainable development, and pointed out the implementation way.

  8. 45 CFR Appendix E to Part 74 - Principles for Determining Costs Applicable to Research and Development Under Grants and...

    Science.gov (United States)

    2010-10-01

    ... unallowable activities such as Gift Shop, Investment Property Management, Fund Raising, and Public Relations... costs as set forth in paragraph IX-B.34. b. The procurement of scarce items for the performance of the...

  9. Cost inefficiency under financial strain: a stochastic frontier analysis of hospitals in Washington State through the Great Recession.

    Science.gov (United States)

    Izón, Germán M; Pardini, Chelsea A

    2017-06-01

    The importance of increasing cost efficiency for community hospitals in the United States has been underscored by the Great Recession and the ever-changing health care reimbursement environment. Previous studies have shown mixed evidence with regards to the relationship between linking hospitals' reimbursement to quality of care and cost efficiency. Moreover, current evidence suggests that not only inherently financially disadvantaged hospitals (e.g., safety-net providers), but also more financially stable providers, experienced declines to their financial viability throughout the recession. However, little is known about how hospital cost efficiency fared throughout the Great Recession. This study contributes to the literature by using stochastic frontier analysis to analyze cost inefficiency of Washington State hospitals between 2005 and 2012, with controls for patient burden of illness, hospital process of care quality, and hospital outcome quality. The quality measures included in this study function as central measures for the determination of recently implemented pay-for-performance programs. The average estimated level of hospital cost inefficiency before the Great Recession (10.4 %) was lower than it was during the Great Recession (13.5 %) and in its aftermath (14.1 %). Further, the estimated coefficients for summary process of care quality indexes for three health conditions (acute myocardial infarction, pneumonia, and heart failure) suggest that higher quality scores are associated with increased cost inefficiency.

  10. A periodic review integrated inventory model with controllable setup cost, imperfect items, and inspection errors under service level constraint

    Science.gov (United States)

    Saga, R. S.; Jauhari, W. A.; Laksono, P. W.

    2017-11-01

    This paper presents an integrated inventory model which consists of single vendor and buyer. The buyer managed its inventory periodically and orders products from the vendor to satisfy the end customer’s demand, where the annual demand and the ordering cost were in the fuzzy environment. The buyer used a service level constraint instead of the stock-out cost term, so that the stock-out level per cycle was bounded. Then, the vendor produced and delivered products to the buyer. The vendor had a choice to commit an investment to reduce the setup cost. However, the vendor’s production process was imperfect, thus the lot delivered contained some defective products. Moreover, the buyer’s inspection process was not error-free since the inspector could be mistaken in categorizing the product’s quality. The objective was to find the optimum value for the review period, the setup cost, and the number of deliveries in one production cycle which might minimize the joint total cost. Furthermore, the algorithm and numerical example were provided to illustrate the application of the model.

  11. 50 CFR 622.31 - Prohibited gear and methods.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Prohibited gear and methods. 622.31... Management Measures § 622.31 Prohibited gear and methods. In addition to the prohibited gear/methods specified in this section, see §§ 622.33, 622.34, and 622.35 for seasonal/area prohibited gear/methods and...

  12. Cost-effectiveness of prenatal food and micronutrient interventions on under-five mortality and stunting: Analysis of data from the MINIMat randomized trial, Bangladesh.

    Directory of Open Access Journals (Sweden)

    Pernilla Svefors

    Full Text Available Nutrition interventions may have favourable as well as unfavourable effects. The Maternal and Infant Nutrition Interventions in Matlab (MINIMat, with early prenatal food and micronutrient supplementation, reduced infant mortality and were reported to be very cost-effective. However, the multiple micronutrients (MMS supplement was associated with an increased risk of stunted growth in infancy and early childhood. This unfavourable outcome was not included in the previous cost-effectiveness analysis. The aim of this study is to evaluate whether the MINIMat interventions remain cost-effective in view of both favourable (decreased under-five-years mortality and unfavourable (increased stunting outcomes.Pregnant women in rural Bangladesh, where food insecurity still is prevalent, were randomized to early (E or usual (U invitation to be given food supplementation and daily doses of 30 mg, or 60 mg iron with 400 μg of folic acid, or MMS with 15 micronutrients including 30 mg iron and 400 μg of folic acid. E reduced stunting at 4.5 years compared with U, MMS increased stunting at 4.5 years compared with Fe60, while the combination EMMS reduced infant mortality compared with UFe60. The outcome measure used was disability adjusted life years (DALYs, a measure of overall disease burden that combines years of life lost due to premature mortality (under five-year mortality and years lived with disability (stunting. Incremental cost effectiveness ratios were calculated using cost data from already published studies.By incrementing UFe60 (standard practice to EMMS, one DALY could be averted at a cost of US$24.When both favourable and unfavourable outcomes were included in the analysis, early prenatal food and multiple micronutrient interventions remained highly cost effective and seem to be meaningful from a public health perspective.

  13. Risk management of energy system for identifying optimal power mix with financial-cost minimization and environmental-impact mitigation under uncertainty

    International Nuclear Information System (INIS)

    Nie, S.; Li, Y.P.; Liu, J.; Huang, Charley Z.

    2017-01-01

    An interval-stochastic risk management (ISRM) method is launched to control the variability of the recourse cost as well as to capture the notion of risk in stochastic programming. The ISRM method can examine various policy scenarios that are associated with economic penalties under uncertainties presented as probability distributions and interval values. An ISRM model is then formulated to identify the optimal power mix for the Beijing's energy system. Tradeoffs between risk and cost are evaluated, indicating any change in targeted cost and risk level would yield different expected costs. Results reveal that the inherent uncertainty of system components and risk attitude of decision makers have significant effects on the city's energy-supply and electricity-generation schemes as well as system cost and probabilistic penalty. Results also disclose that import electricity as a recourse action to compensate the local shortage would be enforced. The import electricity would increase with a reduced risk level; under every risk level, more electricity would be imported with an increased demand. The findings can facilitate the local authority in identifying desired strategies for the city's energy planning and management in association with financial-cost minimization and environmental-impact mitigation. - Highlights: • Interval-stochastic risk management method is launched to identify optimal power mix. • It is advantageous in capturing the notion of risk in stochastic programming. • Results reveal that risk attitudes can affect optimal power mix and financial cost. • Developing renewable energies would enhance the sustainability of energy management. • Import electricity as an action to compensate the local shortage would be enforced.

  14. Prohibitions against Mourning in Childhood Sibling Loss.

    Science.gov (United States)

    Rosen, Helen

    1985-01-01

    Presents findings from a research study on sibling loss in childhood which support the idea that the loss of a sibling in childhood may be an especially significant loss for a child, in that both internal, family, and societal influences prohibit the opportunity to mourn the loss. (Author/NRB)

  15. 16 CFR 611.2 - General prohibition.

    Science.gov (United States)

    2010-01-01

    ... for consumer reports that bear on a consumer's credit worthiness, standing and capacity. Smith Co... information on consumers residing nationwide, and ceases to offer reports containing public record information... TREATMENT AS A NATIONWIDE CONSUMER REPORTING AGENCY § 611.2 General prohibition. (a) A consumer reporting...

  16. 77 FR 58492 - Prohibitions Governing Fire

    Science.gov (United States)

    2012-09-21

    ... DEPARTMENT OF AGRICULTURE Forest Service 36 CFR Part 261 RIN 0596-AD08 Prohibitions Governing Fire AGENCY: Forest Service, USDA. ACTION: Direct final rule. SUMMARY: The Forest Service is making purely... Fire. * * * * * (j) Operating or using any internal or external combustion engine without a spark...

  17. 22 CFR 1104.3 - Prohibited acts.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Prohibited acts. 1104.3 Section 1104.3 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION..., or otherwise alter or deface any archaeological resource located on public lands unless such activity...

  18. 12 CFR 584.2 - Prohibited activities.

    Science.gov (United States)

    2010-01-01

    ... Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS AND LOAN HOLDING COMPANIES § 584.2 Prohibited activities. (a) Evasion of law or regulation. No savings and loan holding... savings and loan holding company or subsidiary thereof that is not a savings association shall commence...

  19. 12 CFR 584.9 - Prohibited acts.

    Science.gov (United States)

    2010-01-01

    ... Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS AND LOAN HOLDING COMPANIES § 584.9 Prohibited acts. (a) Control of mutual savings association. No savings and loan holding company or any subsidiary thereof, or any director, officer, or employee of a savings and loan holding company or...

  20. 45 CFR 1643.3 - Prohibition.

    Science.gov (United States)

    2010-10-01

    ..., EUTHANASIA, AND MERCY KILLING § 1643.3 Prohibition. No recipient may use LSC funds to assist in, support, or... form of legal assistance for the purpose of: (a) Securing or funding any item, benefit, program, or..., euthanasia, or mercy killing of any individual; (b) Compelling any person, institution, or governmental...

  1. 29 CFR 34.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Discrimination prohibited. 34.3 Section 34.3 Labor Office of... THE JOB TRAINING PARTNERSHIP ACT OF 1982, AS AMENDED (JTPA) General Provisions § 34.3 Discrimination... participation in JTPA, be excluded from participation in, denied the benefits of, subjected to discrimination...

  2. 13 CFR 112.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Discrimination prohibited. 112.3... ASSISTED PROGRAMS OF SBA-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 112.3 Discrimination... be otherwise subjected to discrimination by any business or other activity. (b) Specific...

  3. 50 CFR 216.214 - Prohibitions.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking of Marine Mammals Incidental to Explosive Severance Activities Conducted During Offshore Structure Removal Operations on the Outer Continental Shelf in the U.S. Gulf of Mexico § 216.214 Prohibitions. No...

  4. Human embryo cloning prohibited in Hong Kong.

    Science.gov (United States)

    Liu, Athena

    2005-12-01

    Since the birth of Dolly (the cloned sheep) in 1997, debates have arisen on the ethical and legal questions of cloning-for-biomedical-research (more commonly termed "therapeutic cloning") and of reproductive cloning using human gametes. Hong Kong enacted the Human Reproductive Technology Ordinance (Cap 561) in 2000. Section 15(1)(e) of this Ordinance prohibits the "replacing of the nucleus of a cell of an embryo with a nucleus taken from any other cell," i.e., nucleus substitution. Section 15(1)(f) prohibits the cloning of any embryo. The scope of the latter, therefore, is arguably the widest, prohibiting all cloning techniques such as cell nucleus replacement, embryo splitting, parthenogenesis, and cloning using stem cell lines. Although the Human Reproductive Technology Ordinance is not yet fully operative, this article examines how these prohibitions may adversely impact on basic research and the vision of the Hong Kong scientific community. It concludes that in light of recent scientific developments, it is time to review if the law offers a coherent set of policies in this area.

  5. 12 CFR 208.83 - Prohibited practices.

    Science.gov (United States)

    2010-01-01

    ... STATE BANKING INSTITUTIONS IN THE FEDERAL RESERVE SYSTEM (REGULATION H) Consumer Protection in Sales of... practice that would lead a consumer to believe that an extension of credit, in violation of section 106(b... agreement by the consumer not to obtain, or a prohibition on the consumer from obtaining, an insurance...

  6. 12 CFR 14.30 - Prohibited practices.

    Science.gov (United States)

    2010-01-01

    ... and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY CONSUMER PROTECTION IN SALES OF... engage in any practice that would lead a consumer to believe that an extension of credit, in violation of...) An agreement by the consumer not to obtain, or a prohibition on the consumer from obtaining, an...

  7. 12 CFR 536.30 - Prohibited practices.

    Science.gov (United States)

    2010-01-01

    ... Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY CONSUMER PROTECTION IN SALES... in any practice that would lead a consumer to believe that an extension of credit, in violation of... agreement by the consumer not to obtain, or a prohibition on the consumer from obtaining, an insurance...

  8. 12 CFR 343.30 - Prohibited practices.

    Science.gov (United States)

    2010-01-01

    ... CONSUMER PROTECTION IN SALES OF INSURANCE § 343.30 Prohibited practices. (a) Anticoercion and antitying rules. You may not engage in any practice that would lead a consumer to believe that an extension of... annuity sold or offered for sale by you or any subsidiary of the bank is not backed by the Federal...

  9. 18 CFR 420.22 - Prohibition; sanctions.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Prohibition; sanctions. 420.22 Section 420.22 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION... established water pricing schedules of the Commission) of any such use, withdrawal or diversion, and invoke...

  10. 27 CFR 4.39 - Prohibited practices.

    Science.gov (United States)

    2010-04-01

    ... substance found within the wine, and health benefits or effects on health. The term includes both specific... OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Labeling Requirements for Wine § 4.39 Prohibited practices. (a) Statements on labels. Containers of wine, or any label on such containers, or any...

  11. 27 CFR 4.64 - Prohibited practices.

    Science.gov (United States)

    2010-04-01

    ... found within the wine, and health benefits or effects on health. The term includes both specific health... OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Advertising of Wine § 4.64 Prohibited practices. (a) Restrictions. The advertisement of wine shall not contain: (1) Any statement that is false or...

  12. 25 CFR 141.30 - Retaliation prohibited.

    Science.gov (United States)

    2010-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS General Business Practices § 141.30 Retaliation prohibited. No licensee may refuse service to any customer for the purpose of retaliating against that customer for...

  13. 25 CFR 141.22 - Subleasing prohibited.

    Science.gov (United States)

    2010-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES BUSINESS PRACTICES ON THE NAVAJO, HOPI AND ZUNI RESERVATIONS General Business Practices § 141.22 Subleasing prohibited. No licensee may lease, sublet, rent, or sell any building that the licensee occupies for any purpose to any person...

  14. 7 CFR 220.17 - Prohibitions.

    Science.gov (United States)

    2010-01-01

    ..., curriculum, instructions, methods of instruction, and materials of instruction in any school as a condition... CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.17 Prohibitions. (a) In carrying out the... limited to, laws relating to taxation, welfare, and public assistance programs. Expenditure of funds from...

  15. 28 CFR 42.104 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... prohibition also applies to programs as to which a primary objective of the Federal financial assistance is (i... participate in the program as an employee but only to the extent set forth in paragraph (c) of this section... of defeating or substantially impairing accomplishment of the objectives of the program as respects...

  16. 50 CFR 17.104 - Prohibitions.

    Science.gov (United States)

    2010-10-01

    ... PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS (CONTINUED) Manatee Protection Areas § 17.104 Prohibitions. Except as provided in § 17.105, (a) Manatee sanctuary. It is unlawful for any person to engage in any waterborne activity within a manatee sanctuary. (b) Manatee refuge. It is...

  17. 5 CFR 2414.8 - Reporting of prohibited communications; penalties.

    Science.gov (United States)

    2010-01-01

    ... prohibited oral ex parte communication is attempted to be made, shall refuse to listen to the communication... substance of the communication, if it was oral; (3) all written responses to the prohibited communication; and (4) memoranda stating the substance of all oral responses to the prohibited communication. The...

  18. 5 CFR 3501.103 - Prohibited interests in Federal lands.

    Science.gov (United States)

    2010-01-01

    ... ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF THE INTERIOR § 3501.103 Prohibited interests in Federal lands. (a) Cross-references to statutory prohibitions—(1) Prohibited purchases of public land by Bureau... the Bureau of Land Management are prohibited by 43 U.S.C. 11 from directly or indirectly purchasing or...

  19. 40 CFR 63.4 - Prohibited activities and circumvention.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Prohibited activities and circumvention... § 63.4 Prohibited activities and circumvention. (a) Prohibited activities. (1) No owner or operator... part. (3)-(5) [Reserved] (b) Circumvention. No owner or operator subject to the provisions of this part...

  20. 45 CFR 73.735-603 - Prohibited activities.

    Science.gov (United States)

    2010-10-01

    ... partisan election. (b) In addition, certain political activities are prohibited by Federal criminal law: (1... Political Activity § 73.735-603 Prohibited activities. (a) The following are prohibited activities: (1) Serving as an officer of a political party, a member of a national, State or local committee of a...

  1. 48 CFR 1252.237-72 - Prohibition on advertising.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Prohibition on advertising... Prohibition on advertising. As prescribed in (TAR) 48 CFR 1213.7101 and 1237.7003, insert the following clause: Prohibition on Advertising (JAN 1996) The contractor or its representatives (including training instructors...

  2. 48 CFR 222.7301 - Prohibition on use of nonimmigrant aliens.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Prohibition on use of nonimmigrant aliens. 222.7301 Section 222.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION... aliens. (a) Any alien who is issued a visa or otherwise provided nonimmigrant status under Section 101(a...

  3. 36 CFR 261.77 - Prohibitions in Region 8, Southern Region.

    Science.gov (United States)

    2010-07-01

    ... Service Registration Stations abutting the Chattooga River located at Highway 28, Low-Water Bridge, Earl's Ford, Sandy Ford, Highway 76, Woodall Shoals, or Overflow Bridge or unless authorized under special use... this section is prohibited. (d) Entering, going, riding, or floating upon any portion or segment of the...

  4. 31 CFR 12.3 - Sale of tobacco products in vending machines prohibited.

    Science.gov (United States)

    2010-07-01

    ... RESTRICTION OF SALE AND DISTRIBUTION OF TOBACCO PRODUCTS § 12.3 Sale of tobacco products in vending machines prohibited. The sale of tobacco products in vending machines located in or around any Federal building under... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Sale of tobacco products in vending...

  5. 24 CFR 4001.403 - Prohibitions on interested parties in insured mortgage transaction.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Prohibitions on interested parties... under section 257 of the Act shall not improperly influence or attempt to improperly influence through..., inducement, intimidation, nonpayment for services rendered, or bribery, the development, reporting, result or...

  6. 13 CFR 115.62 - Prohibition on participation in Prior Approval program.

    Science.gov (United States)

    2010-01-01

    ... Prior Approval program. 115.62 Section 115.62 Business Credit and Assistance SMALL BUSINESS... in Prior Approval program. A PSB Surety is not eligible to submit applications under subpart B of this part. This prohibition does not extend to an Affiliate, as defined in 13 CFR § 121.103, of a PSB...

  7. 7 CFR 57.700 - Prohibition on disposition of restricted eggs.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Prohibition on disposition of restricted eggs. 57.700... AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) INSPECTION OF EGGS (EGG PRODUCTS INSPECTION ACT) Regulations Governing the Inspection of Eggs...

  8. 7 CFR 57.45 - Prohibition on eggs not intended for use as human food.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Prohibition on eggs not intended for use as human food...) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) INSPECTION OF EGGS (EGG PRODUCTS INSPECTION ACT) Regulations Governing the Inspection of Eggs...

  9. Prediction of Change in Prescription Ingredient Costs and Co-payment Rates under a Reference Pricing System in South Korea.

    Science.gov (United States)

    Heo, Ji Haeng; Rascati, Karen L; Lee, Eui-Kyung

    2017-05-01

    The reference pricing system (RPS) establishes reference prices within interchangeable reference groupings. For drugs priced higher than the reference point, patients pay the difference between the reference price and the total price. To predict potential changes in prescription ingredient costs and co-payment rates after implementation of an RPS in South Korea. Korean National Health Insurance claims data were used as a baseline to develop possible RPS models. Five components of a potential RPS policy were varied: reference groupings, reference pricing methods, co-pay reduction programs, manufacturer price reductions, and increased drug substitutions. The potential changes for prescription ingredient costs and co-payment rates were predicted for the various scenarios. It was predicted that transferring the difference (total price minus reference price) from the insurer to patients would reduce ingredient costs from 1.4% to 22.8% for the third-party payer (government), but patient co-payment rates would increase from a baseline of 20.4% to 22.0% using chemical groupings and to 25.0% using therapeutic groupings. Savings rates in prescription ingredient costs (government and patient combined) were predicted to range from 1.6% to 13.7% depending on various scenarios. Although the co-payment rate would increase, a 15% price reduction by manufacturers coupled with a substitution rate of 30% would result in a decrease in the co-payment amount (change in absolute dollars vs. change in rates). Our models predicted that the implementation of RPS in South Korea would lead to savings in ingredient costs for the third-party payer and co-payments for patients with potential scenarios. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  10. NPV risk simulation of an open pit gold mine project under the O'Hara cost model by using GAs

    Institute of Scientific and Technical Information of China (English)

    Franco-Sepulveda Giovanni; Campuzano Carlos; Pineda Cindy

    2017-01-01

    This paper analyzes an open pit gold mine project based on the O'Hara cost model. Hypothetical data is proposed based on different authors that have studied open pit gold projects, and variations are proposed according to the probability distributions associated to key variables affecting the NPV, like production level, ore grade, price of ore, and others, so as to see what if, in a gold open pit mine project of 3000 metric tons per day of ore. Two case scenarios were analyzed to simulate the NPV, one where there is low certainty data available, and the other where the information available is of high certainty. Results based on genetic algorithm metaheuristic simulations, which combine basically Montecarlo simulations provided by the Palisade Risk software, the O'Hara cost model, net smelter return and financial analysis tools offered by Excel are reported, in order to determine to which variables of the project is more sensitive the NPV.

  11. Making a good group decision (low risk) in Singapore under an environment that has time and cost constraints

    OpenAIRE

    Loo, Sok Hiang Candy

    2014-01-01

    Approved for public release; distribution is unlimited Organizations in Singapore operate in a highly competitive and fast-paced work environment that presents decision-making challenges at the individual, group, and organization levels. A key problem is achieving good decision fitness within time and cost constraints. While many decision-making theories and processes address the fundamental decision-making process, there is limited research on improving the group decision-making framework...

  12. The distribution and magnitude of emissions mitigation costs in climate stabilization under less than perfect international cooperation: SGM results

    International Nuclear Information System (INIS)

    Calvin, Katherine; Patel, Pralit; Fawcett, Allen; Clarke, Leon; Fisher-Vanden, Karen; Edmonds, Jae; Kim, Son H.; Sands, Ron; Wise, Marshall

    2009-01-01

    The EMF22 Transition Scenario subgroup explores the implications of delayed accession on limiting climate change to various radiative forcing levels. This paper focuses on the cost of limiting radiative forcing and the role that industrial leakage plays in scenarios of delayed accession. We find that delayed participation shifts the cost burden toward regions that take early action and away from regions that undertake mitigation later. However, the inefficiencies introduced by delay are so great that present discounted costs are higher in the delayed scenario for regions that delay as well as for regions taking early actions. An important element of these inefficiencies is industrial emissions leakage, that is non-participating regions increase their emissions relative to the reference case. In aggregate, industrial leakage rates are less than 10% if all regions of the world begin emissions mitigation by 2050-higher in carbon-intensive sectors and lower in low-carbon-intensity sectors. Additionally, we consider the implication of technology on carbon prices, the feasibility of limiting radiative forcing to low levels, and the incentives to overshoot the radiative forcing limit.

  13. Whether and under what conditions FDG-PET might be cost-effective in evaluating solitary pulmonary nodules depicted on lung cancer screening in Japan

    International Nuclear Information System (INIS)

    Tsushima, Yoshito; Aoki, Jun; Endo, Keigo

    2003-01-01

    The purpose of this study was to determine whether and under what conditions fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) may be cost-effective in evaluating solitary pulmonary nodules depicted on lung cancer screening in Japan. Three decision models for differentiating lung cancer from benign nodules were compared: CT alone, PET alone, and CT plus PET. The various paths of each strategy were dependent on variables determined from a review of the medical literature. Costs were based on Japanese health insurance. The prevalence of lung cancer among solitary pulmonary nodules detected on lung cancer screening was less than 10%. For this prevalence, the CT-plus-PET model was the cost-effective alternative to the CT-alone model (cost savings were 64,000 yen per patient) and provided greater accuracy (0.90 vs. 0.84). Both of these effects were the result of reducing the number of candidates who undergo unnecessary CT-guided or bronchofiberscopic biopsies or thoracotomy for a benign pulmonary nodule. The CT-plus-PET strategy is accurate and cost-effective for the characterization of solitary pulmonary nodules detected on lung cancer screening in Japan. (author)

  14. Skilled Nursing Facility Partnerships May Decrease 90-Day Costs in a Total Joint Arthroplasty Episode Under the Bundled Payments for Care Improvement Initiative.

    Science.gov (United States)

    Behery, Omar A; Kouk, Shalen; Chen, Kevin K; Mullaly, Kathleen A; Bosco, Joseph A; Slover, James D; Iorio, Richard; Schwarzkopf, Ran

    2018-03-01

    The Bundled Payments for Care Improvement initiative was developed to reduce costs associated with total joint arthroplasty through a single payment for all patient care from index admission through a 90-day post-discharge period, including care at skilled nursing facilities (SNFs). The aim of this study is to investigate whether forming partnerships between hospitals and SNFs could lower the post-discharge costs. We hypothesize that institutionally aligned SNFs have lower post-discharge costs than non-aligned SNFs. A cohort of 615 elective, primary total hip and knee arthroplasty subjects discharged to an SNF under the Bundled Payments for Care Improvement from 2014 to 2016 were included in our analysis. Patients were grouped into one of the 3 categories of SNF alignment: group 1: non-partners; group 2: agreement-based partners; group 3: institution-owned partners. Demographics, comorbidities, length of stay (LOS) at SNF, and associated costs during the 90-day post-operative period were compared between the 3 groups. Mean index hospital LOS was statistically shortest in group 3 (mean 2.7 days vs 3.5 for groups 1 and 2, P = .001). SNF LOS was also shortest in group 3 (mean 11 days vs 19 and 21 days in groups 2 and 1 respectively, P Total SNF costs and total 90-day costs were both significantly lower in group 3 compared with groups 1 and 2 (P total 90-day costs, without increased risk of readmissions, compared with other SNFs. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Costs and benefits of experimentally induced changes in the allocation of growth versus immune function under differential exposure to ectoparasites.

    Directory of Open Access Journals (Sweden)

    Natalia Pitala

    2010-05-01

    Full Text Available Ecological immunology has focused on the costs of investment in immunocompetence. However, understanding optimal resource allocation to immune defence requires also identification of its benefits, which are likely to occur only when parasites are abundant.We manipulated the abundance of parasitic hen fleas in blue tit (Cyanistes caeruleus nests, and supplemented their hosts, the nestlings, with methionine (a sulphur amino acid enhancing cell-mediated immunity during day 3-6. We found a significant interaction between these two experimental factors on the development of immune defences and growth rates. Only in parasitized nests did methionine supplementation boost immune (PHA response, and did nestling with experimentally increased immunocompetence show a relatively faster growth rate than control nestlings between days 6-9. Hence, the allocation of resources into immune defence and its growth-benefits are apparent only in presence of parasites. The main cost of methionine-induced increased allocation to the immune system was an increase in mortality, independently of ectoparasites. Nestlings in all treatments compensated initial growth reduction and all reached equal body size at day 16 (just prior to fledging, indicating a lack of long-term benefits. In addition, methionine treatment tended (P = 0.09 to lower circulating plasma immunoglobulin levels, possibly indicating a trade-off between the cell-mediated and humoral components of the immune system.We found no strong benefits of an increased investment in immunocompetence in a parasite-rich environment. Any deviation from the growth trajectory (due to changes in allocation induced by methionine is largely detrimental for survival. Hence, while costs are apparent identifying the benefits of investment in immunocompetence during ontogeny is challenging.

  16. Cost considerations

    NARCIS (Netherlands)

    Michiel Ras; Debbie Verbeek-Oudijk; Evelien Eggink

    2013-01-01

    Original title: Lasten onder de loep The Dutch government spends almost 7 billion euros  each year on care for people with intellectual disabilities, and these costs are rising steadily. This report analyses what underlies the increase in costs that occurred between 2007 and 2011. Was

  17. Development of an environmental chamber for evaluating the performance of low-cost air quality sensors under controlled conditions

    Science.gov (United States)

    Papapostolou, Vasileios; Zhang, Hang; Feenstra, Brandon J.; Polidori, Andrea

    2017-12-01

    A state-of-the-art integrated chamber system has been developed for evaluating the performance of low-cost air quality sensors. The system contains two professional grade chamber enclosures. A 1.3 m3 stainless-steel outer chamber and a 0.11 m3 Teflon-coated stainless-steel inner chamber are used to create controlled aerosol and gaseous atmospheres, respectively. Both chambers are temperature and relative humidity controlled with capability to generate a wide range of environmental conditions. The system is equipped with an integrated zero-air system, an ozone and two aerosol generation systems, a dynamic dilution calibrator, certified gas cylinders, an array of Federal Reference Method (FRM), Federal Equivalent Method (FEM), and Best Available Technology (BAT) reference instruments and an automated control and sequencing software. Our experiments have demonstrated that the chamber system is capable of generating stable and reproducible aerosol and gas concentrations at low, medium, and high levels. This paper discusses the development of the chamber system along with the methods used to quantitatively evaluate sensor performance. Considering that a significant number of academic and research institutions, government agencies, public and private institutions, and individuals are becoming interested in developing and using low-cost air quality sensors, it is important to standardize the procedures used to evaluate their performance. The information discussed herein provides a roadmap for entities who are interested in characterizing air quality sensors in a rigorous, systematic and reproducible manner.

  18. 12 CFR 215.4 - General prohibitions.

    Science.gov (United States)

    2010-01-01

    .... (i) A member bank with deposits of less than $100,000,000 may by an annual resolution of its board of... of the date of the resolution; (C) The bank meets or exceeds, on a fully-phased in basis, all... 12 Banks and Banking 2 2010-01-01 2010-01-01 false General prohibitions. 215.4 Section 215.4 Banks...

  19. Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607

    Energy Technology Data Exchange (ETDEWEB)

    Ocak, Meltem [Innsbruck Medical University, Clinical Department of Nuclear Medicine, Innsbruck (Austria); Istanbul University, Department of Pharmaceutical Technology, Pharmacy Faculty, Istanbul (Turkey); Helbok, Anna; Rangger, Christine; Decristoforo, Clemens [Innsbruck Medical University, Clinical Department of Nuclear Medicine, Innsbruck (Austria); Peitl, Petra Kolenc [University Medical Centre Ljubljana, Department for Nuclear Medicine, Ljubljana (Slovenia); Nock, Berthold A. [National Center for Scientific Research Demokritos, Molecular Radiopharmacy, Institute of Radioisotopes-Radiodiagnostic Products, Athens (Greece); Morelli, Giancarlo [University of Naples ' ' Federico II' ' and IBB-CN, Department of Biological Sciences, CIRPeB, Naples (Italy); Eek, Annemarie [Radboud University Nijmegen Medical Centre, Department of Nuclear Medicine, Nijmegen (Netherlands); Sosabowski, Jane K. [Institute of Cancer, Barts and the London Queen Mary' s School of Medicine and Dentistry, Centre for Molecular Oncology and Imaging, London (United Kingdom); Breeman, W.A.P. [Erasmus MC Rotterdam, Department of Nuclear Medicine, Rotterdam (Netherlands); Reubi, Jean Claude [University of Berne, Division of Cell Biology and Experimental Cancer Research Institute of Pathology, Berne (Switzerland)

    2011-08-15

    Stability of radiolabelled cholecystokinin 2 (CCK2) receptor targeting peptides has been a major limitation in the use of such radiopharmaceuticals especially for targeted radionuclide therapy applications, e.g. for treatment of medullary thyroid carcinoma (MTC). The purpose of this study was to compare the in vitro stability of a series of peptides binding to the CCK2 receptor [selected as part of the COST Action on Targeted Radionuclide Therapy (BM0607)] and to identify major cleavage sites. Twelve different 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid (DOTA)-minigastrin/CCK conjugates were provided within an European COST Action (BM0607) by different laboratories and radiolabelled with {sup 177}Lu. Their in vitro stabilities were tested in fresh human serum. Radiochemical yields (RCY) and intact radioligands for half-life calculations were determined by radio-HPLC. Matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) analysis of metabolites was performed to identify cleavage products using conjugates labelled with excess stable {sup nat}Lu, incubated in serum at 37 C. Urine metabolite analysis after injection in normal mice was performed by radio-HPLC analysis. Variable stability in human serum was found for the different peptides with calculated half-lives between 4.5 {+-} 0.1 h and 198 {+-} 0.1 h (n = 2). In urine of normal mice only metabolised peptide fragments were detected even at short times after injection for all peptides. MALDI-TOF MS revealed a major cleavage site of all minigastrin derivatives between Asp and Phe-NH{sub 2} at the C-terminal end. Development of CCK2 receptor ligands especially for therapeutic purposes in patients with MTC or small cell lung cancer (SCLC) is still ongoing in different laboratories. This comparative study provided valuable insight into the importance of biological stability especially in the context of other results of this comparative

  20. Targeting the underlying causes of undernutrition. Cost-effectiveness of a multifactorial personalized intervention in community-dwelling older adults: A randomized controlled trial.

    Science.gov (United States)

    van der Pols-Vijlbrief, Rachel; Wijnhoven, Hanneke A H; Bosmans, Judith E; Twisk, Jos W R; Visser, Marjolein

    2017-12-01

    Undernutrition in old age is associated with increased morbidity, mortality and health care costs. Treatment by caloric supplementation results in weight gain, but compliance is poor in the long run. Few studies targeted underlying causes of undernutrition in community-dwelling older adults. This study aimed to evaluate the cost-effectiveness of a multifactorial personalized intervention focused on eliminating or managing the underlying causes of undernutrition to prevent and reduce undernutrition in comparison with usual care. A randomized controlled trial was performed among 155 community-dwelling older adults receiving home care with or at risk of undernutrition. The intervention included a personalized action plan and 6 months support. The control group received usual care. Body weight, and secondary outcomes were measured in both groups at baseline and 6 months follow-up. Multiple imputation, linear regression and generalized estimating equation analyses were used to analyze intervention effects. In the cost-effectiveness analyses regression models were bootstrapped to estimate statistical uncertainty. This intervention showed no statistically significant effects on body weight, mid-upper arm circumference, grip strength, gait speed and 12-Item Short-Form Health Survey physical component scale as compared to usual care, but there was an effect on the 12-Item Short-Form Health Survey mental component scale (0-100) (β = 8.940, p=0.001). Borderline significant intervention effects were found for both objective and subjective physical function measures, Short Physical Performance Battery (0-12) (β = 0.56, p=0.08) and ADL-Barthel score (0-20) (β = 0.69, p=0.09). Societal costs in the intervention group were statistically non-significantly lower than in the control group (mean difference -274; 95% CI -1111; 782). Cost-effectiveness acceptability curves showed that the probability of cost-effectiveness was 0.72 at a willingness-to-pay of 1000

  1. Stochastic Funding of a Defined Contribution Pension Plan with Proportional Administrative Costs and Taxation under Mean-Variance Optimization Approach

    Directory of Open Access Journals (Sweden)

    Charles I Nkeki

    2014-11-01

    Full Text Available This paper aim at studying a mean-variance portfolio selection problem with stochastic salary, proportional administrative costs and taxation in the accumulation phase of a defined contribution (DC pension scheme. The fund process is subjected to taxation while the contribution of the pension plan member (PPM is tax exempt. It is assumed that the flow of contributions of a PPM are invested into a market that is characterized by a cash account and a stock. The optimal portfolio processes and expected wealth for the PPM are established. The efficient and parabolic frontiers of a PPM portfolios in mean-variance are obtained. It was found that capital market line can be attained when initial fund and the contribution rate are zero. It was also found that the optimal portfolio process involved an inter-temporal hedging term that will offset any shocks to the stochastic salary of the PPM.

  2. The total cost of logistics in supplier selection, under conditions of multiple sourcing, multiple criteria and capacity constraint

    Directory of Open Access Journals (Sweden)

    Elnaz Bani

    2016-06-01

    Full Text Available This paper presents a mathematical model to solve a multi-objective decision making supplier selection problem. The proposed problem considers three objective functions: the first objective function minimizes the cost of purchasing the products while the second objective function minimizes the due dates and finally the third objective function maximizes the customer satisfaction. The resulted problem is formulated as mixed integer programming and, therefore, we use invasive weed optimization technique to solve the resulted problem. The performance of the proposed model is compared with NSGA II based on different criteria such as mean ideal distance and quality matrix. The preliminary results indicate that the proposed model performs relatively well compared with alternative method.

  3. A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions.

    Science.gov (United States)

    Cheung, C Y Maurice; Williams, Thomas C R; Poolman, Mark G; Fell, David A; Ratcliffe, R George; Sweetlove, Lee J

    2013-09-01

    Flux balance models of metabolism generally utilize synthesis of biomass as the main determinant of intracellular fluxes. However, the biomass constraint alone is not sufficient to predict realistic fluxes in central heterotrophic metabolism of plant cells because of the major demand on the energy budget due to transport costs and cell maintenance. This major limitation can be addressed by incorporating transport steps into the metabolic model and by implementing a procedure that uses Pareto optimality analysis to explore the trade-off between ATP and NADPH production for maintenance. This leads to a method for predicting cell maintenance costs on the basis of the measured flux ratio between the oxidative steps of the oxidative pentose phosphate pathway and glycolysis. We show that accounting for transport and maintenance costs substantially improves the accuracy of fluxes predicted from a flux balance model of heterotrophic Arabidopsis cells in culture, irrespective of the objective function used in the analysis. Moreover, when the new method was applied to cells under control, elevated temperature and hyper-osmotic conditions, only elevated temperature led to a substantial increase in cell maintenance costs. It is concluded that the hyper-osmotic conditions tested did not impose a metabolic stress, in as much as the metabolic network is not forced to devote more resources to cell maintenance. © 2013 The Authors The Plant Journal © 2013 John Wiley & Sons Ltd.

  4. Obesity-specific neural cost of maintaining gait performance under complex conditions in community-dwelling older adults.

    Science.gov (United States)

    Osofundiya, Olufunmilola; Benden, Mark E; Dowdy, Diane; Mehta, Ranjana K

    2016-06-01

    Recent evidence of obesity-related changes in the prefrontal cortex during cognitive and seated motor activities has surfaced; however, the impact of obesity on neural activity during ambulation remains unclear. The purpose of this study was to determine obesity-specific neural cost of simple and complex ambulation in older adults. Twenty non-obese and obese individuals, 65years and older, performed three tasks varying in the types of complexity of ambulation (simple walking, walking+cognitive dual-task, and precision walking). Maximum oxygenated hemoglobin, a measure of neural activity, was measured bilaterally using a portable functional near infrared spectroscopy system, and gait speed and performance on the complex tasks were also obtained. Complex ambulatory tasks were associated with ~2-3.5 times greater cerebral oxygenation levels and ~30-40% slower gait speeds when compared to the simple walking task. Additionally, obesity was associated with three times greater oxygenation levels, particularly during the precision gait task, despite obese adults demonstrating similar gait speeds and performances on the complex gait tasks as non-obese adults. Compared to existing studies that focus solely on biomechanical outcomes, the present study is one of the first to examine obesity-related differences in neural activity during ambulation in older adults. In order to maintain gait performance, obesity was associated with higher neural costs, and this was augmented during ambulatory tasks requiring greater precision control. These preliminary findings have clinical implications in identifying individuals who are at greater risk of mobility limitations, particularly when performing complex ambulatory tasks. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Cost-Benefit Performance of Robotic Surgery Compared with Video-Assisted Thoracoscopic Surgery under the Japanese National Health Insurance System.

    Science.gov (United States)

    Kajiwara, Naohiro; Patrick Barron, James; Kato, Yasufumi; Kakihana, Masatoshi; Ohira, Tatsuo; Kawate, Norihiko; Ikeda, Norihiko

    2015-01-01

    Medical economics have significant impact on the entire country. The explosion in surgical techniques has been accompanied by questions regarding actual improvements in outcome and cost-effectiveness, such as the da Vinci(®) Surgical System (dVS) compared with conventional video-assisted thoracic surgery (VATS). To establish a medical fee system for robot-assisted thoracic surgery (RATS), which is a system not yet firmly established in Japan. This study examines the cost benefit performance (CBP) based on medical fees compared with VATS and RATS under the Japanese National Health Insurance System (JNHIS) introduced in 2012. The projected (but as yet undecided) price in the JNHIS would be insufficient if institutions have less than even 200 dVS cases per year. Only institutions which perform more than 300 dVS operations per year would obtain a positive CBP with the projected JNHIS reimbursement. Thus, under the present conditions, it is necessary to perform at least 300 dVS operations per year in each institution with a dVS system to avoid financial deficit with current robotic surgical management. This may hopefully encourage a downward price revision of the dVS equipment by the manufacture which would result in a decrease in the cost per procedure.

  6. Affective attention under cognitive load: reduced emotional biases but emergent anxiety-related costs to inhibitory control

    Science.gov (United States)

    Berggren, Nick; Richards, Anne; Taylor, Joseph; Derakshan, Nazanin

    2013-01-01

    Trait anxiety is associated with deficits in attentional control, particularly in the ability to inhibit prepotent responses. Here, we investigated this effect while varying the level of cognitive load in a modified antisaccade task that employed emotional facial expressions (neutral, happy, and angry) as targets. Load was manipulated using a secondary auditory task requiring recognition of tones (low load), or recognition of specific tone pitch (high load). Results showed that load increased antisaccade latencies on trials where gaze toward face stimuli should be inhibited. This effect was exacerbated for high anxious individuals. Emotional expression also modulated task performance on antisaccade trials for both high and low anxious participants under low cognitive load, but did not influence performance under high load. Collectively, results (1) suggest that individuals reporting high levels of anxiety are particularly vulnerable to the effects of cognitive load on inhibition, and (2) support recent evidence that loading cognitive processes can reduce emotional influences on attention and cognition. PMID:23717273

  7. Contracting under asymmetric holding cost information in a serial supply chain with a nearly profit maximizing buyer

    OpenAIRE

    Guido Voigt

    2012-01-01

    Screening contracts (or non-linear "menu of contracts") are frequently used for aligning the incentives in supply chains with private information. In this context, it is assumed that all supply chain parties are strictly (expected) profit maximizing and, therefore, sensible to even arbitrarily small pay-off differences between contract alternatives. However, previous behavioral work on contracting under asymmetric information in supply chains shows that agents (buyers) are not always strictly...

  8. Uptake, outcomes, and costs of antenatal, well-baby, and prevention of mother-to-child transmission of HIV services under routine care conditions in Zambia.

    Directory of Open Access Journals (Sweden)

    Callie A Scott

    Full Text Available BACKGROUND: Zambia adopted Option A for prevention of mother-to-child transmission of HIV (PMTCT in 2010 and announced a move to Option B+ in 2013. We evaluated the uptake, outcomes, and costs of antenatal, well-baby, and PMTCT services under routine care conditions in Zambia after the adoption of Option A. METHODS: We enrolled 99 HIV-infected/HIV-exposed (index mother/baby pairs with a first antenatal visit in April-September 2011 at four study sites and 99 HIV-uninfected/HIV-unexposed (comparison mother/baby pairs matched on site, gestational age, and calendar month at first visit. Data on patient outcomes and resources utilized from the first antenatal visit through six months postpartum were extracted from site registers. Costs in 2011 USD were estimated from the provider's perspective. RESULTS: Index mothers presented for antenatal care at a mean 23.6 weeks gestation; 55% were considered to have initiated triple-drug antiretroviral therapy (ART based on information recorded in site registers. Six months postpartum, 62% of index and 30% of comparison mother/baby pairs were retained in care; 67% of index babies retained had an unknown HIV status. Comparison and index mother/baby pairs utilized fewer resources than under fully guideline-concordant care; index babies utilized more well-baby resources than comparison babies. The average cost per comparison pair retained in care six months postpartum was $52 for antenatal and well-baby services. The average cost per index pair retained was $88 for antenatal, well-baby, and PMTCT services and increased to $185 when costs of triple-drug ART services were included. CONCLUSIONS: HIV-infected mothers present to care late in pregnancy and many are lost to follow up by six months postpartum. HIV-exposed babies are more likely to remain in care and receive non-HIV, well-baby care than HIV-unexposed babies. Improving retention in care, guideline concordance, and moving to Option B+ will result in

  9. The metabolic costs of improving ethanol yield by reducing glycerol formation capacity under anaerobic conditions in Saccharomyces cerevisiae.

    Science.gov (United States)

    Pagliardini, Julien; Hubmann, Georg; Alfenore, Sandrine; Nevoigt, Elke; Bideaux, Carine; Guillouet, Stephane E

    2013-03-28

    Finely regulating the carbon flux through the glycerol pathway by regulating the expression of the rate controlling enzyme, glycerol-3-phosphate dehydrogenase (GPDH), has been a promising approach to redirect carbon from glycerol to ethanol and thereby increasing the ethanol yield in ethanol production. Here, strains engineered in the promoter of GPD1 and deleted in GPD2 were used to investigate the possibility of reducing glycerol production of Saccharomyces cerevisiae without jeopardising its ability to cope with process stress during ethanol production. For this purpose, the mutant strains TEFmut7 and TEFmut2 with different GPD1 residual expression were studied in Very High Ethanol Performance (VHEP) fed-batch process under anaerobic conditions. Both strains showed a drastic reduction of the glycerol yield by 44 and 61% while the ethanol yield improved by 2 and 7% respectively. TEFmut2 strain showing the highest ethanol yield was accompanied by a 28% reduction of the biomass yield. The modulation of the glycerol formation led to profound redox and energetic changes resulting in a reduction of the ATP yield (YATP) and a modulation of the production of organic acids (acetate, pyruvate and succinate). Those metabolic rearrangements resulted in a loss of ethanol and stress tolerance of the mutants, contrarily to what was previously observed under aerobiosis. This work demonstrates the potential of fine-tuned pathway engineering, particularly when a compromise has to be found between high product yield on one hand and acceptable growth, productivity and stress resistance on the other hand. Previous study showed that, contrarily to anaerobiosis, the resulting gain in ethanol yield was accompanied with no loss of ethanol tolerance under aerobiosis. Moreover those mutants were still able to produce up to 90 gl-1 ethanol in an anaerobic SSF process. Fine tuning metabolic strategy may then open encouraging possibilities for further developing robust strains with improved

  10. Changing HIV treatment eligibility under health system constraints in sub-Saharan Africa: investment needs, population health gains, and cost-effectiveness.

    Science.gov (United States)

    Hontelez, Jan A C; Chang, Angela Y; Ogbuoji, Osondu; de Vlas, Sake J; Bärnighausen, Till; Atun, Rifat

    2016-09-24

    We estimated the investment needs, population health gains, and cost-effectiveness of different policy options for scaling-up prevention and treatment of HIV in the 10 countries that currently comprise 80% of all people living with HIV in sub-Saharan Africa (Ethiopia, Kenya, Malawi, Mozambique, Nigeria, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe). We adapted the established STDSIM model to capture the health system dynamics: demand-side and supply-side constraints in the delivery of antiretroviral treatment (ART). We compared different scenarios of supply-side (i.e. health system capacity) and demand-side (i.e. health seeking behavior) constraints, and determined the impact of changing guidelines to ART eligibility at any CD4 cell count within these constraints. Continuing current scale-up would require US$178 billion by 2050. Changing guidelines to ART at any CD4 cell count is cost-effective under all constraints tested in the model, especially in demand-side constrained health systems because earlier initiation prevents loss-to-follow-up of patients not yet eligible. Changing guidelines under current demand-side constraints would avert 1.8 million infections at US$208 per life-year saved. Treatment eligibility at any CD4 cell count would be cost-effective, even under health system constraints. Excessive loss-to-follow-up and mortality in patients not eligible for treatment can be avoided by changing guidelines in demand-side constrained systems. The financial obligation for sustaining the AIDS response in sub-Saharan Africa over the next 35 years is substantial and requires strong, long-term commitment of policy-makers and donors to continue to allocate substantial parts of their budgets.

  11. Cost-oriented evaluation of ecosystem services under consideration of income risks and risk attitudes of farmers.

    Science.gov (United States)

    Dörschner, T; Musshoff, O

    2013-09-30

    Agri-environmental measures are often not as accepted among farmers as is expected. The present study investigates whether changes in income risks and the individual risk attitudes of farmers may constitute an explanatory approach for the low acceptance of the measures. For this purpose, a normative model is developed that calculates the premia claimed by the farmers for adopting environmental measures under the consideration of income risks and different risk attitudes. We apply this model to environmental measures aiming at an increase of the faunistic diversity of species on grassland and showing that changes in income risks and the decision makers' risk attitudes can significantly influence farmers' minimum compensation claims. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Shellfish Harvest Prohibition Areas for 2011; shellfish11

    Data.gov (United States)

    University of Rhode Island Geospatial Extension Program — Geospatial vector polygon data defining shellfishing prohibition areas, seasonal, and conditional shellfish closure areas, and areas open to legal shellfish...

  13. Cost-effective production of cellulose hydrolysing enzymes from Trichoderma sp. RCK65 under SSF and its evaluation in saccharification of cellulosic substrates.

    Science.gov (United States)

    Chakraborty, Subhojit; Gupta, Rishi; Jain, Kavish Kumar; Kuhad, Ramesh Chander

    2016-11-01

    Trichoderma sp. is a potential cellulase producing mesophilic fungi which grow under mild acidic condition. In this study, growth and nutritional conditions were manipulated for the maximum and cost-effective production of cellulase using lab strain Trichoderma sp. RCK65 and checked for its efficiency in hydrolysis of Prosopis juliflora (a woody substrate). Preliminary studies suggested that when 48 h old secondary fungal culture (20 % v/w) was inoculated in wheat bran moistened with mineral salt solution (pH 4.5 and 1:3 solid to moisture ratio), incubated at 30 °C and after 72 h, it produced maximum cellulase (CMCase 145 U/gds, FPase 38 U/gds and β-glucosidase 105 U/gds). However, using statistical approach a S:L ratio (1:1) was surprisingly found to be optimum that improved cellulase that is CMCase activity by 6.21 %, FPase activity by 23.68 % and β-glucosidase activity by 37.28 %. The estimated cost of crude enzyme (Rs. 5.311/1000 FPase units) seems to be economically feasible which may be due to high enzyme titre, less cultivation time and low media cost. Moreover, when the crude enzyme was used to saccharify pretreated Prosopis juliflora (a woody substrate), it resulted up to 83 % (w/w) saccharification.

  14. Adaptive Differential Evolution Approach for Constrained Economic Power Dispatch with Prohibited Operating Zones

    Directory of Open Access Journals (Sweden)

    Abdellatif HAMOUDA

    2011-12-01

    Full Text Available Economic power dispatch (EPD is one of the main tools for optimal operation and planning of modern power systems. To solve effectively the EPD problem, most of the conventional calculus methods rely on the assumption that the fuel cost characteristic of a generating unit is a continuous and convex function, resulting in inaccurate dispatch. This paper presents the design and application of efficient adaptive differential evolution (ADE algorithm for the solution of the economic power dispatch problem, where the non-convex characteristics of the generators, such us prohibited operating zones and ramp rate limits of the practical generator operation are considered. The 26 bus benchmark test system with 6 units having prohibited operating zones and ramp rate limits was used for testing and validation purposes. The results obtained demonstrate the effectiveness of the proposed method for solving the non-convex economic dispatch problem.

  15. Spatial and temporal distribution of long term public policy costs under uncertainty, the case of climate change

    International Nuclear Information System (INIS)

    Lecocq, F.

    2000-07-01

    Because of the inertia of the climate system, policy makers cannot avoid making early decisions regarding climate change in a sea of uncertainties. In this context, the very legitimacy of economic analysis to tackle such questions, and in particular the underlying equity issues (who pays for climate mitigation? when?) faces widespread skepticism. This thesis aims at demonstrating how public economy still remains a powerful tool to try and put some rationale into the debate, by checking the internal consistency of the different discourses, and by providing robust insights, if not definitive answers, into climate decisions. We use a set of compact integrated climate policy optimization models to progressively introduce, articulate, and assess numerically the prominent issues at stake. We obtain three main results. We first demonstrate that the so-called timing debate between short term and long term action cannot be reduced to a mere dispute over discount rate. Given the high uncertainties surrounding climate change indeed, the margins of freedom we pass on to future generations, and in particular the technical and institutional systems we transmit, become more important than the discount rate value. Secondly, we apply the various emission quota allocation rules proposed in the literature for the enlargement of annex B to developing economies. We show that the distributive outcome of these rules depends critically on ex ante assumptions about future economic and emission growth. Therefrom, we conclude that a careful design of the institutions surrounding the tradable permits market is a necessary condition to enhance the systems robustness. Last, on a broader perspective, this thesis illustrates the complementarity between ethics and economics: though the economist does not have per se a superior word about what is fair, his toolbox is powerful enough to show how some intuitively appealing ideas, such as a zero discount rate to take care of both present and future

  16. An evaluation of the parents under pressure programme: a study protocol for an RCT into its clinical and cost effectiveness.

    Science.gov (United States)

    Barlow, Jane; Sembi, Sukhdev; Gardner, Frances; Macdonald, Geraldine; Petrou, Stavros; Parsons, Helen; Harnett, Paul; Dawe, Sharon

    2013-07-11

    Many babies in the UK are born to drug-dependent parents, and dependence on psychoactive drugs during the postnatal period is associated with high rates of child maltreatment, with around a quarter of these children being subject to a child protection plan. Parents who are dependent on psychoactive drugs are at risk of a wide range of parenting problems, and studies have found reduced sensitivity and responsiveness to both the infant's physical and emotional needs. The poor outcomes that are associated with such drug dependency appear to be linked to the multiple difficulties experienced by such parents.An increase in understanding about the crucial importance of early relationships for infant well-being has led to a focus on the development and delivery of services that are aimed at supporting parenting and parent-infant interactions. The Parents under Pressure (PuP) programme is aimed at supporting parents who are dependent on psychoactive drugs or alcohol by providing them with methods of managing their emotional regulation, and of supporting their new baby's development. An evaluation of the PuP programme in Australia with parents on methadone maintenance of children aged 3 to 8 years found significant reductions in child abuse potential, rigid parenting attitudes and child behaviour problems. The study comprises a multicentre randomised controlled trial using a mixed-methods approach to data collection and analysis in order to identify which families are most able to benefit from this intervention.The study is being conducted in six family centres across the UK, and targets primary caregivers of children less than 2.5 years of age who are substance dependent. Consenting participants are randomly allocated to either the 20-week PuP programme or to standard care.The primary outcome is child abuse potential, and secondary outcomes include substance use, parental mental health and emotional regulation, parenting stress, and infant/toddler socio

  17. 75 FR 47464 - Exemption to Prohibition on Circumvention of Copyright Protection Systems for Access Control...

    Science.gov (United States)

    2010-08-06

    ... Prohibition on Circumvention of Copyright Protection Systems for Access Control Technologies AGENCY: Copyright... nonsubstantial correction to its regulation announcing the prohibition against circumvention of technological... the final rule governing exemption to prohibition on circumvention of copyright protection systems for...

  18. Direct-to-Consumer Drug Advertising Prohibition in Ethiopia: Health ...

    African Journals Online (AJOL)

    Abstract. Ethiopia prohibited direct-to-consumer advertising (DTCA) for any drug product since the early 1980s. This total drug advertising prohibition is rare, and possibly unique, in the world. The purpose of this study was to determine the knowledge and perceptions of health professionals on issues regarding DTCA.

  19. 22 CFR 1414.8 - Reporting of prohibited communications; penalties.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Reporting of prohibited communications... unauthorized ex parte communication, shall place or cause to be placed on the public record of the proceeding... rebut those contained in the prohibited communication. All such responses shall be placed in the public...

  20. 24 CFR 100.50 - Real estate practices prohibited.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Real estate practices prohibited....50 Real estate practices prohibited. (a) This subpart provides the Department's interpretation of... in, any multiple-listing service, real estate brokers' association, or other service organization or...

  1. 47 CFR 76.505 - Prohibition on buy outs.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Prohibition on buy outs. 76.505 Section 76.505... CABLE TELEVISION SERVICE Ownership of Cable Systems § 76.505 Prohibition on buy outs. (a) No local... operator's franchise area. (c) A local exchange carrier and a cable operator whose telephone service area...

  2. 12 CFR 313.99 - Prohibited actions by employer.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Prohibited actions by employer. 313.99 Section 313.99 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE PROCEDURES FOR CORPORATE DEBT COLLECTION Administrative Wage Garnishment § 313.99 Prohibited actions by...

  3. 14 CFR 120.17 - Use of prohibited drugs.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Use of prohibited drugs. 120.17 Section 120...) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Air Traffic Controllers § 120.17 Use of prohibited drugs. (a) Each employer shall provide...

  4. 14 CFR 120.33 - Use of prohibited drugs.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Use of prohibited drugs. 120.33 Section 120...) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL... prohibited drugs. (a) This section applies to individuals who perform a function listed in subpart E of this...

  5. 14 CFR 120.35 - Testing for prohibited drugs.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Testing for prohibited drugs. 120.35... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND... for prohibited drugs. (a) Each certificate holder or operator shall test each of its employees who...

  6. 32 CFR 228.14 - Prohibition on gambling.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Prohibition on gambling. 228.14 Section 228.14...) MISCELLANEOUS SECURITY PROTECTIVE FORCE § 228.14 Prohibition on gambling. Participating in games for money or other personal property, or the operating of gambling devices, the conduct of a lottery, or the selling...

  7. 40 CFR 65.11 - Circumvention and prohibited activities.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Circumvention and prohibited... PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE General Provisions § 65.11 Circumvention and prohibited activities. (a) Circumvention. (1) No owner or operator subject to the provisions of this part shall build...

  8. 12 CFR 585.30 - What actions are prohibited?

    Science.gov (United States)

    2010-01-01

    ... SAVINGS AND LOAN HOLDING COMPANIES Prohibition § 585.30 What actions are prohibited? (a) Person. If a...: (1) Become, or continue as, an institution-affiliated party with respect to any savings and loan holding company. (2) Own or control, directly or indirectly, any savings and loan holding company. A...

  9. 47 CFR 18.303 - Prohibited frequency bands.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Prohibited frequency bands. 18.303 Section 18.303 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT Technical Standards § 18.303 Prohibited frequency bands. Operation of ISM equipment within the...

  10. 32 CFR 228.10 - Prohibition on alcohol.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Prohibition on alcohol. 228.10 Section 228.10 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SECURITY PROTECTIVE FORCE § 228.10 Prohibition on alcohol. Entering or being on protected property...

  11. 29 CFR 3.9 - Prohibited payroll deductions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Prohibited payroll deductions. 3.9 Section 3.9 Labor Office of the Secretary of Labor CONTRACTORS AND SUBCONTRACTORS ON PUBLIC BUILDING OR PUBLIC WORK FINANCED IN WHOLE OR IN PART BY LOANS OR GRANTS FROM THE UNITED STATES § 3.9 Prohibited payroll deductions...

  12. 12 CFR 723.2 - What are the prohibited activities?

    Science.gov (United States)

    2010-01-01

    ... MEMBER BUSINESS LOANS § 723.2 What are the prohibited activities? (a) Who is ineligible to receive a... senior management employees is tied to the profit or sale of the business or commercial endeavor for... 12 Banks and Banking 6 2010-01-01 2010-01-01 false What are the prohibited activities? 723.2...

  13. 5 CFR 4.1 - Prohibition against political activity.

    Science.gov (United States)

    2010-01-01

    ... political campaigns, except as may be provided by or pursuant to statute. All such persons shall retain the... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Prohibition against political activity. 4... PRACTICES (RULE IV) § 4.1 Prohibition against political activity. No person employed in the executive branch...

  14. 41 CFR 101-6.204 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Discrimination prohibited. 101-6.204 Section 101-6.204 Public Contracts and Property Management Federal Property Management...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.204 Discrimination prohibited. ...

  15. 33 CFR 183.512 - Fuel tanks: Prohibited materials.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Fuel tanks: Prohibited materials... tanks: Prohibited materials. (a) A fuel tank must not be constructed from terneplate. (b) Unless it has an inorganic sacrificial galvanic coating on the inside and outside of the tank, a fuel tank must not...

  16. 45 CFR 73.735-802 - Executive order prohibitions.

    Science.gov (United States)

    2010-10-01

    ... CONDUCT Financial Interest § 73.735-802 Executive order prohibitions. (a) Basic prohibition of Executive Order 11222. (1) An employee shall not have a direct or indirect financial interest that conflicts... employee need not have a financial interest that actually conflicts with his or her duties to violate the...

  17. 12 CFR 956.3 - Prohibited investments and prudential rules.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Prohibited investments and prudential rules... prudential rules. (a) Prohibited investments. A Bank may not invest in: (1) Instruments that provide an... the Bank provides to the issuer the customized terms, necessary liquidity, or favorable pricing...

  18. 25 CFR 247.18 - What are the sanitation prohibitions?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What are the sanitation prohibitions? 247.18 Section 247.18 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE USE OF COLUMBIA RIVER TREATY FISHING ACCESS SITES § 247.18 What are the sanitation prohibitions? (a) You cannot deposit...

  19. 29 CFR 2.13 - Audiovisual coverage prohibited.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Audiovisual coverage prohibited. 2.13 Section 2.13 Labor Office of the Secretary of Labor GENERAL REGULATIONS Audiovisual Coverage of Administrative Hearings § 2.13 Audiovisual coverage prohibited. The Department shall not permit audiovisual coverage of the...

  20. 5 CFR 2635.205 - Proper disposition of prohibited gifts.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Proper disposition of prohibited gifts... STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE EXECUTIVE BRANCH Gifts From Outside Sources § 2635.205 Proper disposition of prohibited gifts. (a) An employee who has received a gift that cannot be accepted...

  1. 45 CFR 2490.130 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false General prohibitions against discrimination. 2490.130 Section 2490.130 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON... ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.130 General prohibitions...

  2. 46 CFR 105.05-2 - Prohibitions regarding petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Prohibitions regarding petroleum products. 105.05-2... VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Application § 105.05-2 Prohibitions regarding petroleum products. (a) Commercial fishing vessels shall not transport Grade A flammable liquids...

  3. Reducing diarrhoea deaths in South Africa: costs and effects of scaling up essential interventions to prevent and treat diarrhoea in under-five children.

    Science.gov (United States)

    Chola, Lumbwe; Michalow, Julia; Tugendhaft, Aviva; Hofman, Karen

    2015-04-17

    Diarrhoea is one of the leading causes of morbidity and mortality in South African children, accounting for approximately 20% of under-five deaths. Though progress has been made in scaling up multiple interventions to reduce diarrhoea in the last decade, challenges still remain. In this paper, we model the cost and impact of scaling up 13 interventions to prevent and treat childhood diarrhoea in South Africa. Modelling was done using the Lives Saved Tool (LiST). Using 2014 as the baseline, intervention coverage was increased from 2015 until 2030. Three scale up scenarios were compared: by 2030, 1) coverage of all interventions increased by ten percentage points; 2) intervention coverage increased by 20 percentage points; 3) and intervention coverage increased to 99%. The model estimates 13 million diarrhoea cases at baseline. Scaling up intervention coverage averted between 3 million and 5.3 million diarrhoea cases. In 2030, diarrhoeal deaths are expected to reduce from an estimated 5,500 in 2014 to 2,800 in scenario one, 1,400 in scenario two and 100 in scenario three. The additional cost of implementing all 13 interventions will range from US$510 million (US$9 per capita) to US$960 million (US$18 per capita), of which the health system costs range between US$40 million (less than US$1 per capita) and US$170 million (US$3 per capita). Scaling up 13 essential interventions could have a substantial impact on reducing diarrhoeal deaths in South African children, which would contribute toward reducing child mortality in the post-MDG era. Preventive measures are key and the government should focus on improving water, sanitation and hygiene. The investments required to achieve these results seem feasible considering current health expenditure.

  4. Hybrid coolers under part-load conditions - Optimisation of operating costs and energy consumption; Simulation und Berechnung von hybriden Trockenkuehlern imTeillastbereich - Optimierung von Betriebskosten und Energieverbrauch

    Energy Technology Data Exchange (ETDEWEB)

    Koenig, H.

    2007-07-01

    This comprehensive article takes a look at new European guidelines on the energy performance of buildings in which the total efficiency of the buildings or heat-transportation systems under partial loading is considered. On the basis of a real-life example, the author examines the influence of various components such as compressors, pumps and ventilators on energy consumption. Hybrid coolers are looked at and the characteristics of refrigeration machines with respect to varying outside temperature are discussed. Combined cooling for computer centres is examined and switchable, redundant combined systems are looked at. Optimisation of cooling systems for falling outside temperatures and the operation of cold-water systems are looked at. Simulation topics are discussed and optimisation with respect to costs and energy consumption are examined.

  5. 14 CFR 91.25 - Aviation Safety Reporting Program: Prohibition against use of reports for enforcement purposes.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aviation Safety Reporting Program... GENERAL OPERATING AND FLIGHT RULES General § 91.25 Aviation Safety Reporting Program: Prohibition against... to the National Aeronautics and Space Administration under the Aviation Safety Reporting Program (or...

  6. 49 CFR 385.14 - Motor carriers, brokers, and freight forwarders delinquent in paying civil penalties: prohibition...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Motor carriers, brokers, and freight forwarders....14 Motor carriers, brokers, and freight forwarders delinquent in paying civil penalties: prohibition... commerce under 49 CFR 386.83. (b) A broker, freight forwarder, or for-hire motor carrier that has failed to...

  7. Costing of Paediatric Treatment alongside Clinical Trials under Low Resource Constraint Environments: Cotrimoxazole and Antiretroviral Medications in Children Living with HIV/AIDS

    Directory of Open Access Journals (Sweden)

    Bona M. Chitah

    2016-01-01

    Full Text Available Introduction. Costing evidence is essential for policy makers for priority setting and resource allocation. It is in this context that the clinical trials of ARVs and cotrimoxazole provided a costing component to provide evidence for budgeting and resource needs alongside the clinical efficacy studies. Methods. A micro based costing approach was adopted, using case record forms for maintaining patient records. Costs for fixed assets were allocated based on the paediatric space. Medication and other resource costs were costed using the WHO/MSH Drug Price Indicators as well as procurement data where these were available. Results. The costs for cotrimoxazole and ARVs are significantly different. The average costs for human resources were US$22 and US$71 for physician costs and $1.3 and $16 for nursing costs while in-patient costs were $257 and $15 for the cotrimoxazole and ARV cohorts, respectively. Mean or average costs were $870 for the cotrimoxazole cohort and $218 for the ARV. The causal factors for the significant cost differences are attributable to the higher human resource time, higher infections of opportunistic conditions, and longer and higher frequency of hospitalisations, among others.

  8. Rebuilding the eastern Baltic cod stock under environmental change (part II): taking into account the costs of a marine protected area

    NARCIS (Netherlands)

    Roeckmann, C.; Tol, R.S.J.; Schneider, U.A.; St.John, M.A.

    2009-01-01

    This study adds a cost analysis of the Eastern Baltic cod fishery to the existing model presented in Röckmann et al. [2007a]. As cost data on this international fishery do not exist, data from Denmark are extrapolated to the whole international fishery. Additionally, unit and total variable costs

  9. 7 CFR 319.73-2 - Products prohibited importation.

    Science.gov (United States)

    2010-01-01

    ... the fungus Hemileia vastatrix (Berkely and Broome), which causes an injurious rust disease, the..., seeds of all kinds when in pulp, including coffee berries or fruits, are prohibited importation into all...

  10. 47 CFR 1.3002 - Structural rules and prohibitions.

    Science.gov (United States)

    2010-10-01

    ... bequest to the Commission from a regulated entity or other prohibited source; or (2) Accept gifts of cash... conflict of interest or the appearance of a conflict of interest. Agency ethics officials may also advise...

  11. 77 FR 3037 - Proposed Exemptions From Certain Prohibited Transaction Restrictions

    Science.gov (United States)

    2012-01-20

    ... Vol. 77 Friday, No. 13 January 20, 2012 Part II Department of Labor Employee Benefits Security... Employee Benefits Security Administration Proposed Exemptions From Certain Prohibited Transaction Restrictions AGENCY: Employee Benefits Security Administration, Labor. ACTION: Notice of Proposed Exemptions...

  12. 22 CFR 96.36 - Prohibition on child buying.

    Science.gov (United States)

    2010-04-01

    ... Accreditation and Approval Ethical Practices and Responsibilities § 96.36 Prohibition on child buying. (a) The... person may remit reasonable payments for activities related to the adoption proceedings, pre-birth and.... Professional Qualifications and Training for Employees ...

  13. 76 FR 14083 - Proposed Exemptions From Certain Prohibited Transaction Restrictions

    Science.gov (United States)

    2011-03-15

    ... firms that litigate securities fraud cases on a contingency fee basis. Finally, IFS stated that the... DEPARTMENT OF LABOR Employee Benefits Security Administration Proposed Exemptions From Certain Prohibited Transaction Restrictions AGENCY: Employee Benefits Security Administration, Labor. ACTION: Notice...

  14. 11 CFR 7.7 - Prohibited conduct-General.

    Science.gov (United States)

    2010-01-01

    ... Government efficiency or economy; (d) Losing independence or impartiality; (e) Making a Government decision... Employees or Commissioners § 7.7 Prohibited conduct—General. A Commissioner or employee shall avoid any...

  15. 45 CFR 30.18 - Interest, penalties, and administrative costs.

    Science.gov (United States)

    2010-10-01

    ... delinquency, or as otherwise provided by law. For debts not paid by the date specified in the written demand... direct (personnel, supplies, etc.) and indirect collection costs, including the cost of providing a... consideration of waiver if statute prohibits collection of the debt during this period. (i) Common law or other...

  16. Assessing and forecasting groundwater development costs in Sub ...

    African Journals Online (AJOL)

    Greater use of groundwater in Sub-Saharan Africa is a pre-requisite for improved human welfare; however, the costs associated with groundwater development are prohibitively high and poorly defined. This study identifies and disaggregates the costs of groundwater development in 11 Sub-Saharan African countries, while ...

  17. The Human Cloning Prohibition Act of 2001: vagueness and federalism.

    Science.gov (United States)

    Swartz, Jonathan S

    2002-01-01

    On July 31, 2001, the U.S. House of Representatives passed The Human Cloning Prohibition Act of 2001. The legislation proposes a complete ban on somatic cell nuclear transfer to create cloned human embryos; it threatens transgressors with criminal punishment and civil fines. House Bill 2505 is the first human cloning prohibition to pass either chamber of Congress. This note argues that the bill is unconstitutionally vague and inconsistent with the Supreme Court's recent Commerce Clause jurisprudence.

  18. The toxicology of cannabis and cannabis prohibition.

    Science.gov (United States)

    Grotenhermen, Franjo

    2007-08-01

    The acute side effects caused by cannabis use are mainly related to psyche and cognition, and to circulation. Euphoria, anxiety, changes in sensory perception, impairment of memory and psychomotor performance are common effects after a dose is taken that exceeds an individually variable threshold. Cannabis consumption may increase heart rate and change blood pressure, which may have serious consequences in people with heart disease. Effects of chronic use may be induction of psychosis and development of dependency to the drug. Effects on cognitive abilities seem to be reversible after abstinence, except possibly in very heavy users. Cannabis exposure in utero may have negative consequences on brain development with subtle impairment of cognitive abilities in later life. Consequences of cannabis smoking may be similar to those of tobacco smoking and should be avoided. Use by young people has more detrimental effects than use by adults. There appear to be promising therapeutic uses of cannabis for a range of indications. Use of moderate doses in a therapeutic context is usually not associated with severe side effects. Current prohibition on cannabis use may also have harmful side effects for the individual and the society, while having little influence on prevalence of use. Harm is greatest for seriously ill people who may benefit from a treatment with cannabis. This makes it difficult to justify criminal penalties against patients.

  19. A Simple, Cost-Effective Sensor for Detecting Lead Ions in Water Using Under-Potential Deposited Bismuth Sub-Layer with Differential Pulse Voltammetry (DPV)

    Science.gov (United States)

    Dai, Yifan; Liu, Chung Chiun

    2017-01-01

    This research has developed a simple to use, cost effective sensor system for the detection of lead ions in tap water. An under-potential deposited bismuth sub-layer on a thin gold film based electrochemical sensor was designed, manufactured, and evaluated. Differential pulse voltammetry (DPV) measurement technique was employed in this detection. Tap water from the Cleveland, OH, USA regional water district was the test medium. Concentrations of lead ion in the range of 8 × 10−7 M to 5 × 10−4 M were evaluated, showing a good sensitivity over this concentration range. The calibration curve for the DPV measurements of lead ions in tap water showed excellent reproducibility with R2 value of 0.970. This DPV detection system required 3–6 min to complete the detection measurement. A longer measurement time of 6 min was used for the lower lead ion concentration. The selectivity of this lead ion sensor was very good, and Fe III, Cu II, Ni II, and Mg II at a concentration level of 5 × 10−4 M did not interfere with the lead ion measurement. PMID:28441356

  20. 45 CFR 309.150 - What start-up costs are allowable for Tribal IV-D programs carried out under § 309.65(b) of this...

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What start-up costs are allowable for Tribal IV-D... ENFORCEMENT (IV-D) PROGRAM Tribal IV-D Program Funding § 309.150 What start-up costs are allowable for Tribal... $500,000, unless additional funding is provided pursuant to § 309.16(c). Allowable start-up costs and...

  1. Cost Effectiveness of the Angiotensin Receptor Neprilysin Inhibitor Sacubitril/Valsartan for Patients with Chronic Heart Failure and Reduced Ejection Fraction in the Netherlands: A Country Adaptation Analysis Under the Former and Current Dutch Pharmacoeconomic Guidelines.

    Science.gov (United States)

    Ramos, Isaac Corro; Versteegh, Matthijs M; de Boer, Rudolf A; Koenders, Jolanda M A; Linssen, Gerard C M; Meeder, Joan G; Rutten-van Mölken, Maureen P M H

    2017-12-01

    To describe the adaptation of a global health economic model to determine whether treatment with the angiotensin receptor neprilysin inhibitor LCZ696 is cost effective compared with the angiotensin-converting enzyme inhibitor enalapril in adult patients with chronic heart failure with reduced left ventricular ejection fraction in the Netherlands; and to explore the effect of performing the cost-effectiveness analyses according to the new pharmacoeconomic Dutch guidelines (updated during the submission process of LCZ696), which require a value-of-information analysis and the inclusion of indirect medical costs of life-years gained. We adapted a UK model to reflect the societal perspective in the Netherlands by including travel expenses, productivity loss, informal care costs, and indirect medical costs during the life-years gained and performed a preliminary value-of-information analysis. The incremental cost-effectiveness ratio obtained was €17,600 per quality-adjusted life-year (QALY) gained. This was robust to changes in most structural assumptions and across different subgroups of patients. Probability sensitivity analysis results showed that the probability that LCZ696 is cost-effective at a €50,000 per QALY threshold is 99.8%, with a population expected value of perfect information of €297,128. On including indirect medical costs of life-years gained, the incremental cost-effectiveness ratio was €26,491 per QALY gained, and LCZ696 was 99.46% cost effective at €50,000 per QALY, with a population expected value of perfect information of €2,849,647. LCZ696 is cost effective compared with enalapril under the former and current Dutch guidelines. However, the (monetary) consequences of making a wrong decision were considerably different in both scenarios. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  2. Characterization of a Large, Low-Cost 3D Scanner

    Directory of Open Access Journals (Sweden)

    Jeremy Straub

    2015-01-01

    Full Text Available Imagery-based 3D scanning can be performed by scanners with multiple form factors, ranging from small and inexpensive scanners requiring manual movement around a stationary object to large freestanding (nearly instantaneous units. Small mobile units are problematic for use in scanning living creatures, which may be unwilling or unable to (or for the very young and animals, unaware of the need to hold a fixed position for an extended period of time. Alternately, very high cost scanners that can capture a complete scan within a few seconds are available, but they are cost prohibitive for some applications. This paper seeks to assess the performance of a large, low-cost 3D scanner, presented in prior work, which is able to concurrently capture imagery from all around an object. It provides the capabilities of the large, freestanding units at a price point akin to the smaller, mobile ones. This allows access to 3D scanning technology (particularly for applications requiring instantaneous imaging at a lower cost. Problematically, prior analysis of the scanner’s performance was extremely limited. This paper characterizes the efficacy of the scanner for scanning both inanimate objects and humans. Given the importance of lighting to visible light scanning systems, the scanner’s performance under multiple lighting configurations is evaluated, characterizing its sensitivity to lighting design.

  3. Incremental cost-effectiveness of percutaneous versus surgical closure of atrial septal defects in children under a public health system perspective in Brazil.

    Science.gov (United States)

    Costa, Rodrigo; Pedra, Carlos A C; Ribeiro, Marcelo; Pedra, Simone; Ferreira-Da-Silva, André Luis; Polanczyk, Carisi; Berwanger, Otávio; Biasi, Alexandre; Ribeiro, Rodrigo

    2014-11-01

    Cost-effectiveness (CE) studies of percutaneous (PC) versus surgical (SC) atrial septal defect closure are lacking. A systematic literature review in children and a CE analysis based on a model of long-term outcomes were performed. Direct costs of PC and SC were US$8700 (defined arbitrarily) and US$5700 (actually paid), respectively. Three-times the Brazilian GDI (US$28,700) per year of life saved (with a discount rate of 5%) was used as a limit for willingness-to-pay. PC had a high (US$104,500) incremental CE ratio despite lower complication rates, shorter hospital stay and better (nonsignificant) adjusted life expectancy. PC would be cost-effective if it cost US$6400 or SC had an 8% loss of utility or its indirect costs were US$2250. Costs of PC should be reduced to be cost-effective in the Brazilian public health system. Indirect costs and impact on quality of life should be further assessed.

  4. 45 CFR 309.145 - What costs are allowable for Tribal IV-D programs carried out under § 309.65(a) of this part?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What costs are allowable for Tribal IV-D programs... ENFORCEMENT (IV-D) PROGRAM Tribal IV-D Program Funding § 309.145 What costs are allowable for Tribal IV-D... maintenance of essential Office Automation capability; (4) Establishment of Intergovernmental Service...

  5. Cost-effectiveness of granulocyte colony-stimulating factor prophylaxis in chemotherapy-induced febrile neutropenia among breast cancer and Non-Hodgkin's lymphoma patients under Taiwan's national health insurance system.

    Science.gov (United States)

    Wen, Tsun-Jen; Wen, Yu-Wen; Chien, Chun-Ru; Chiang, Shao-Chin; Hsu, William Wei-Yuan; Shen, Li-Jiuan; Hsiao, Fei-Yuan

    2017-04-01

    The beneficial effects of granulocyte colony-stimulating factor (G-CSF) prophylaxis on reducing the risk of chemotherapy-induced febrile neutropenia (CIFN) were well documented throughout the literature. However, existing data regarding its cost-effectiveness were conflicting. We estimated the cost-effectiveness of G-CSF prophylaxis in CIFN under Taiwan's National Health Insurance (NHI) system. Data on clinical outcomes and direct medical costs were derived for 5179 newly diagnosed breast cancer and 629 non-Hodgkin's lymphoma (NHL) patients from the NHI claims database. Patients were further categorized into three subgroups as "primary-", "secondary-" and "no -" prophylaxis based on their patterns of G-CSF use. Generalized estimating equations were applied to estimate the impact of G-CSF use on the incidence of CIFN. The incremental cost-effectiveness ratios of primary and secondary prophylactic G-CSF use were calculated and sensitivity analyses were performed. Primary prophylaxis of G-CSF decreased the incidence of CIFN by 27% and 83%, while secondary prophylaxis by 34% and 22% in breast cancer and NHL patients, respectively. Compared with those with no prophylaxis, the incremental cost per CIFN reduced in primary prophylaxis is $931 and $52 among patients with breast cancer and NHL, respectively. In contrast, secondary prophylaxis is dominated by no prophylaxis and primary prophylaxis in both cancer patients. Primary but not secondary prophylactic use of G-CSF was cost-effective in CIFN in breast cancer and NHL patients under Taiwan's NHI system. © 2016 John Wiley & Sons, Ltd.

  6. Cost-Effectiveness Analysis of Test-Based versus Presumptive Treatment of Uncomplicated Malaria in Children under Five Years in an Area of High Transmission in Central Ghana

    DEFF Research Database (Denmark)

    Tawiah, Theresa; Hansen, Kristian Schultz; Baiden, Frank

    2016-01-01

    about household cost incurred on transport, drugs, fees, and special food during a period of one week after the health centre visit as well as days unable to work. A decision model approach was used to calculate the incremental cost-effectiveness ratios (ICERs). Univariate and multivariate sensitivity...... (ACT) in all suspected malaria patients. The use of malaria rapid diagnostic tests (mRDTs) would make it possible for prescribers to diagnose malaria at point-of-care and better target the use of antimalarials. Therefore, a cost-effectiveness analysis was performed on the introduction of m......) or clinical judgement (control) was used to measure the effect of mRDTs on appropriate treatment: ‘a child with a positive reference diagnosis prescribed a course of ACT or a child with a negative reference diagnosis not given an ACT’. Cost data was collected from five purposively selected health centres...

  7. 27 CFR 7.54 - Prohibited statements.

    Science.gov (United States)

    2010-04-01

    ... statement of alcoholic content permitted under § 7.71 may be depicted in any advertising media. The... statement of alcoholic content permitted under § 7.71 may be displayed in any advertising media. (d) Class..., DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF MALT BEVERAGES Advertising of Malt Beverages...

  8. 34 CFR 100.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ... Acceleration Act, Pub. L. 87-658, 42 U.S.C. 2641-2643. (B) Work-study under the Vocational Education Act of... limited, or for which preference is given, to students, fellows, or other persons in training for the same or related employments. (D) Assistance to rehabilitation facilities under the Vocational...

  9. 45 CFR 80.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... Act, Pub. L. 87-658, 42 U.S.C. 2641-2643. (b) Work-study under the Vocational Education Act of 1963... are limited, or for which preference is given, to students, fellows, or other persons in training for the same or related employments. (d) Assistance to rehabilitation facilities under the Vocational...

  10. The management of small area burns and unexpected illness after burn in children under five years of age - A costing study in the English healthcare setting.

    Science.gov (United States)

    Kandiyali, R; Sarginson, J H; Hollén, L I; Spickett-Jones, F; Young, A E R

    2018-02-01

    The objective of this economic study was to evaluate the resource use and cost associated with the management of small area burns, including the additional costs associated with unexpected illness after burn in children of less than five years of age. This study was conducted as a secondary analysis of a multi-centre prospective observational cohort study investigating the physiological response to burns in children. 452 children were included in the economic analysis (median age=1.60years, 61.3% boys, median total burn surface area [TBSA]=1.00%) with a mean length of stay of 0.69 days. Of these children, 21.5% re-presented to medical care with an unexpected illness within fourteen days of injury. The cost of managing a burn of less than 10% TBSA in a child less than five years of age was £785. The additional cost associated with the management of illness after burn was £1381. A generalised linear regression model was used to determine the association between an unexpected illness after burn, presenting child characteristics and NHS cost. Our findings may be of value to those planning economic evaluations of novel technologies in burn care. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

  11. Cost-Sharing Contracts for Energy Saving and Emissions Reduction of a Supply Chain under the Conditions of Government Subsidies and a Carbon Tax

    Directory of Open Access Journals (Sweden)

    Yi Yuyin

    2018-03-01

    Full Text Available To study the cooperation of upstream and downstream enterprises of a supply chain in energy saving and emissions reduction, we establish a Stackelberg game model. The retailer moves first to decide a cost-sharing contract, then the manufacturer determines the energy-saving level, carbon-emission level, and wholesale price successively. In the end, the retailer determines the retail price. As a regulation, the government provides subsidies for energy-saving products, while imposing a carbon tax on the carbon emitted. The results show that (1 both the energy-saving cost-sharing (ECS and the carbon emissions reduction cost-sharing (CCS contracts are not the dominant strategy of the two parties by which they can facilitate energy savings and emissions reductions; (2 compared with single cost-sharing contracts, the bivariate cost-sharing (BCS contract for energy saving and emissions reduction is superior, although it still cannot realise prefect coordination of the supply chain; (3 government subsidy and carbon tax policies can promote the cooperation of both the upstream and downstream enterprises of the supply chain—a subsidy policy can always drive energy saving and emissions reductions, while a carbon tax policy does not always exert positive effects, as it depends on the initial level of pollution and the level of carbon tax; and (4 the subsidy policy reduces the coordination efficiency of the supply chain, while the influences of carbon tax policy upon the coordination efficiency relies on the initial carbon-emission level.

  12. 76 FR 44282 - Defense Federal Acquisition Regulation Supplement; Prohibition on Interrogation of Detainees by...

    Science.gov (United States)

    2011-07-25

    ...-AG88 Defense Federal Acquisition Regulation Supplement; Prohibition on Interrogation of Detainees by... prescribes policies prohibiting interrogation of detainees by contractor personnel, as required by section... ancillary positions, including as trainers of, and advisors to, interrogations, if the contractor personnel...

  13. The impact of power market structure on CO2 cost pass-through to electricity prices under quantity competition. A theoretical approach

    International Nuclear Information System (INIS)

    Sijm, J.; Chen, Y.; Hobbs, B.F.

    2012-01-01

    We present a theoretical analysis of the impact of power market structure on the pass-through rate (PTR) of CO2 emissions trading (ET) costs on electricity prices. Market structure refers in particular to the number of firms active in the market and the intensity of oligopolistic competition as measured by the conjectural variation, as well as to the functional form of the power demand and supply curves. In addition, we analyse briefly the impact of other power market-related factors on the PTR of carbon costs to electricity prices. These include in particular the impact of ET-induced changes in the merit order of power generation technologies and the impact of pursuing other market strategies besides maximising generator profit, such as maximising market shares or sales revenues of power companies. Each of these factors can have a significant impact on the rate of passing-through carbon costs to electricity prices.

  14. Antibiotic expected effectiveness and cost under real life microbiology: evaluation of ertapenem and ceftriaxone in the treatment of community-acquired pneumonia for elderly patients in Spain

    Science.gov (United States)

    Grau, Santiago; Lozano, Virginia; Valladares, Amparo; Cavanillas, Rafael; Xie, Yang; Nocea, Gonzalo

    2014-01-01

    Background Clinical efficacy of antibiotics may be affected by changes in the susceptibility of microorganisms to antimicrobial agents. The purpose of this study is to assess how these changes could affect the initial efficacy of ertapenem and ceftriaxone in the treatment of community-acquired pneumonia (CAP) in elderly patients and the potential consequences this may have in health care costs. Methods Initial efficacy in elderly was obtained from a combined analysis of two multicenter, randomized studies. An alternative scenario was carried out using initial efficacy data according to the pneumonia severity index (PSI). Country-specific pathogens distribution was obtained from a national epidemiological study, and microbiological susceptibilities to first- and second-line therapies were obtained from Spanish or European surveillance studies. A decision analytic model was used to compare ertapenem versus ceftriaxone for CAP inpatient treatment. Inputs of the model were the expected effectiveness previously estimated and resource use considering a Spanish national health system perspective. Outcomes include difference in proportion of successfully treated patients and difference in total costs between ertapenem and ceftriaxone. The model performed one-way and probabilistic sensitivity analyses. Results First-line treatment of CAP with ertapenem led to a higher proportion of successfully treated patients compared with ceftriaxone in Spain. One-way sensitivity analysis showed that length of stay was the key parameter of the model. Probabilistic sensitivity analysis showed that ertapenem can be a cost-saving strategy compared with ceftriaxone, with a 59% probability of being dominant (lower costs with additional health benefits) for both, elderly patients (>65 years) and patients with PSI >3. Conclusion The incorporation of the current antimicrobial susceptibility into the initial clinical efficacy has a significant impact in outcomes and costs in CAP treatment. The

  15. Cost-competitiveness of organic photovoltaics for electricity self-consumption at residential buildings: A comparative study of Denmark and Greece under real market conditions

    DEFF Research Database (Denmark)

    Chatzisideris, Marios Dimos; Laurent, Alexis; Christoforidis, Georgios C.

    2017-01-01

    To address sustainability challenges, photovoltaics (PV) are regarded as a promising renewable energy technology. Decreasing PV module costs and increasing residential electricity prices have made self-consumption of PV-generated electricity financially more attractive than exporting to the grid....... Organic photovoltaics (OPV) are an emerging thin-film PV technology that shows promise of greatly improving the environmental and economic performances of PV technologies. Previous studies have estimated the current and future costs of OPV technologies, but the attractiveness of investing in OPV systems...

  16. Bariatric surgery tourism hidden costs? How Canada is not doing its part in covering bariatric surgery under the Canada Health Act.

    Science.gov (United States)

    Gagner, Michel

    2017-08-01

    Many Canadians seek medical treatment outside our borders. Waiting times, rather than lack of expertise, are the number one culprit, and with globalization of health care, the number of patients who travel to obtain medical care will continue to rise. Though the provinces have covered the costs of complications from surgeries performed abroad for many years, complications from bariatric surgery performed abroad have been receiving negative attention. This commentary discusses associated costs and questions how the Canada Health Act should be covering bariatric procedures.

  17. Antibiotic expected effectiveness and cost under real life microbiology: evaluation of ertapenem and ceftriaxone in the treatment of community-acquired pneumonia for elderly patients in Spain

    Directory of Open Access Journals (Sweden)

    Grau S

    2014-02-01

    Full Text Available Santiago Grau,1 Virginia Lozano,2 Amparo Valladares,3 Rafael Cavanillas,4 Yang Xie,5 Gonzalo Nocea3 1Hospital del Mar, Barcelona, Spain; 2Pharmacoeconomics and Outcomes Research Iberia, Madrid, Spain; 3Outcomes Research Merck Sharp and Dohme Ltd, Madrid, Spain; 4Medical Affairs, Merck Sharp and Dohme Ltd, Madrid, Spain; 5Global Health Outcomes, Merck Sharp and Dohme Ltd, Whitehouse Station, NJ, USA Background: Clinical efficacy of antibiotics may be affected by changes in the susceptibility of microorganisms to antimicrobial agents. The purpose of this study is to assess how these changes could affect the initial efficacy of ertapenem and ceftriaxone in the treatment of community-acquired pneumonia (CAP in elderly patients and the potential consequences this may have in health care costs. Methods: Initial efficacy in elderly was obtained from a combined analysis of two multicenter, randomized studies. An alternative scenario was carried out using initial efficacy data according to the pneumonia severity index (PSI. Country-specific pathogens distribution was obtained from a national epidemiological study, and microbiological susceptibilities to first- and second-line therapies were obtained from Spanish or European surveillance studies. A decision analytic model was used to compare ertapenem versus ceftriaxone for CAP inpatient treatment. Inputs of the model were the expected effectiveness previously estimated and resource use considering a Spanish national health system perspective. Outcomes include difference in proportion of successfully treated patients and difference in total costs between ertapenem and ceftriaxone. The model performed one-way and probabilistic sensitivity analyses. Results: First-line treatment of CAP with ertapenem led to a higher proportion of successfully treated patients compared with ceftriaxone in Spain. One-way sensitivity analysis showed that length of stay was the key parameter of the model. Probabilistic

  18. Aquifer thermal-energy-storage costs with a seasonal-chill source

    Science.gov (United States)

    Brown, D. R.

    1983-01-01

    The cost of energy supplied by an aquifer thermal energy storage (ATES) ystem from a seasonal chill source was investigated. Costs were estimated for point demand and residential development ATES systems using the computer code AQUASTOR. AQUASTOR was developed at PNL specifically for the economic analysis of ATES systems. In this analysis the cost effect of varying a wide range of technical and economic parameters was examined. Those parameters exhibiting a substantial influence on the costs of ATES delivered chill were: system size; well flow rate; transmission distance; source temperature; well depth; and cost of capital. The effects of each parameter are discussed. Two primary constraints of ATES chill systems are the extremely low energy density of the storage fluid and the prohibitive costs of lengthly pipelines for delivering chill to residential users. This economic analysis concludes that ATES-delivered chill will not be competitive for residential cooling applications. The otherwise marginal attractiveness of ATES chill systems vanishes under the extremely low load factors characteristic of residential cooling systems. (LCL)

  19. 9 CFR 95.3 - Byproducts from diseased animals prohibited.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Byproducts from diseased animals prohibited. 95.3 Section 95.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS...

  20. 50 CFR 660.112 - Trawl fishery-prohibitions.

    Science.gov (United States)

    2010-10-01

    ... reports of groundfish landings, containing all data, and in the exact manner, required by the regulation.../Biogenic Area, Farallon Islands/Fanny Shoal, Half Moon Bay, Monterey Bay/Canyon, Point Sur Deep, Big Sur... prohibited from fishing, landing, or processing primary season Pacific whiting with a catcher/processor...

  1. Uranium Mining and Nuclear Facilities (Prohibitions) Act 1986 No. 194

    International Nuclear Information System (INIS)

    1986-01-01

    The purpose of this Act is to protect the health and safety of the people of New South Wales and its environment. Accordingly it prohibits prospecting or mining for uranium and the construction and operation of nuclear reactors and other facilities in the nuclear fuel cycle. (NEA) [fr

  2. 29 CFR 102.132 - Reporting of prohibited communications; penalties.

    Science.gov (United States)

    2010-07-01

    ... communication shall place or cause to be placed on the public record of the proceeding: (1) The communication... 29 Labor 2 2010-07-01 2010-07-01 false Reporting of prohibited communications; penalties. 102.132 Section 102.132 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES AND REGULATIONS...

  3. 75 FR 54542 - Prohibited Transaction Exemption Procedures; Employee Benefit Plans

    Science.gov (United States)

    2010-09-08

    ... DEPARTMENT OF LABOR Employee Benefits Security Administration 29 CFR Part 2570 RIN 1210-AA98 Prohibited Transaction Exemption Procedures; Employee Benefit Plans Correction In proposed rule document 2010-21073 beginning on page 53172 in the issue of Monday, August 30, 2010, make the following correction...

  4. 76 FR 66637 - Prohibited Transaction Exemption Procedures; Employee Benefit Plans

    Science.gov (United States)

    2011-10-27

    ... DEPARTMENT OF LABOR Employee Benefits Security Administration 29 CFR Part 2570 RIN 1210-AB49 Prohibited Transaction Exemption Procedures; Employee Benefit Plans AGENCY: Employee Benefits Security... Determinations, Employee Benefits Security Administration, Room N-5700, U.S. Department of Labor, Washington, DC...

  5. 5 CFR 6401.102 - Prohibited financial interests.

    Science.gov (United States)

    2010-01-01

    ... ETHICAL CONDUCT FOR EMPLOYEES OF THE ENVIRONMENTAL PROTECTION AGENCY § 6401.102 Prohibited financial... having outside employment with or holding stock or any other financial interest in companies that... apply to companies with subsidiaries in these areas but do not include retail distributors to the...

  6. 16 CFR 1117.9 - Prohibited acts and sanctions.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Prohibited acts and sanctions. 1117.9 Section 1117.9 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT....C. 1001. (b) A failure to report to the Commission in a timely fashion as required by this part is a...

  7. 77 FR 36149 - Disclosure Requirements and Prohibitions Concerning Franchising

    Science.gov (United States)

    2012-06-18

    ... FTC announces revised monetary thresholds for three exemptions from the Franchise Rule. FTC is... July 1, 2012. FOR FURTHER INFORMATION CONTACT: Craig Tregillus, Franchise Rule Coordinator, Division of... and Prohibitions Concerning Franchising'' (Franchise Rule or Rule) \\1\\ provides three exemptions based...

  8. 34 CFR 76.657 - Separate classes prohibited.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Separate classes prohibited. 76.657 Section 76.657 Education Office of the Secretary, Department of Education STATE-ADMINISTERED PROGRAMS What Conditions Must... separately on the basis of school enrollment or religion of the students if: (a) The classes are at the same...

  9. 15 CFR 922.132 - Prohibited or otherwise regulated activities.

    Science.gov (United States)

    2010-01-01

    ... from a cruise ship, any material or other matter, except: (A) Fish, fish parts, chumming materials, or... MBTA. (6) Flying motorized aircraft, except as necessary for valid law enforcement purposes, at less... prohibition does not apply to possession of fish resulting from fishing below 3000 feet within the Davidson...

  10. 34 CFR 303.123 - Prohibition against commingling.

    Science.gov (United States)

    2010-07-01

    ... assurance in this section is satisfied by the use of an accounting system that includes an “audit trail” of... TODDLERS WITH DISABILITIES State Application for a Grant Statement of Assurances § 303.123 Prohibition against commingling. The statement must include an assurance satisfactory to the Secretary that funds made...

  11. 12 CFR 410.130 - General prohibitions against discrimination.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false General prohibitions against discrimination. 410.130 Section 410.130 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY EXPORT-IMPORT BANK OF THE UNITED...

  12. 5 CFR 6201.102 - Prohibited financial interests.

    Science.gov (United States)

    2010-01-01

    ... Section 6201.102 Administrative Personnel EXPORT-IMPORT BANK OF THE UNITED STATES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE EXPORT-IMPORT BANK OF THE UNITED STATES § 6201.102 Prohibited...) All exporters that, during the preceding two fiscal years, exported an aggregate dollar volume of...

  13. 12 CFR 410.149 - Program accessibility: Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Program accessibility: Discrimination prohibited. 410.149 Section 410.149 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY EXPORT-IMPORT BANK OF THE UNITED...

  14. 50 CFR 640.27 - Spiny lobster import prohibitions.

    Science.gov (United States)

    2010-10-01

    ... ATLANTIC Management Measures § 640.27 Spiny lobster import prohibitions. (a) Minimum size limits for... than Puerto Rico or the U.S. Virgin Islands, and a more restrictive minimum size limit that applies to Puerto Rico and the U.S. Virgin Islands. (1) No person may import a spiny lobster with less than a 5...

  15. 50 CFR 622.50 - Caribbean spiny lobster import prohibitions.

    Science.gov (United States)

    2010-10-01

    ... ATLANTIC Management Measures § 622.50 Caribbean spiny lobster import prohibitions. (a) Minimum size limits... States other than Puerto Rico or the U.S. Virgin Islands, and a more restrictive minimum size limit that applies to Puerto Rico and the U.S. Virgin Islands. (1) No person may import a Caribbean spiny lobster...

  16. 17 CFR 2.3 - Prohibitions against misuse of seal.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Prohibitions against misuse of seal. 2.3 Section 2.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OFFICIAL... character, or with wrongful or fraudulent intent, using, buying, procuring, selling or transferring to...

  17. 29 CFR 801.4 - Prohibitions on lie detector use.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Prohibitions on lie detector use. 801.4 Section 801.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION... complaint, for testifying in any proceeding, or for exercising any rights afforded by the Act. (b) An...

  18. 41 CFR 51-10.149 - Program accessibility: Discrimination prohibited.

    Science.gov (United States)

    2010-07-01

    ...: Discrimination prohibited. 51-10.149 Section 51-10.149 Public Contracts and Property Management Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 10... FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.149 Program accessibility...

  19. 15 CFR 922.163 - Prohibited activities-Sanctuary-wide.

    Science.gov (United States)

    2010-01-01

    ... an exotic species of plant, invertebrate, fish, amphibian, or mammals into the Sanctuary. (8) Damage... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Prohibited activities-Sanctuary-wide... RESOURCE MANAGEMENT NATIONAL MARINE SANCTUARY PROGRAM REGULATIONS Florida Keys National Marine Sanctuary...

  20. 40 CFR 763.165 - Manufacture and importation prohibitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Manufacture and importation...) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Prohibition of the Manufacture, Importation, Processing, and Distribution in Commerce of Certain Asbestos-Containing Products; Labeling Requirements § 763.165 Manufacture...

  1. 40 CFR 80.27 - Controls and prohibitions on gasoline volatility.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Controls and prohibitions on gasoline... prohibitions on gasoline volatility. (a)(1) Prohibited activities in 1991. During the 1991 regulatory control... shall sell, offer for sale, dispense, supply, offer for supply, or transport gasoline whose Reid vapor...

  2. 36 CFR 51.42 - Are there exceptions to this compensable interest prohibition?

    Science.gov (United States)

    2010-07-01

    ... compensable interest prohibition? 51.42 Section 51.42 Parks, Forests, and Public Property NATIONAL PARK... exceptions to this compensable interest prohibition? Two exceptions to this compensable interest prohibition... owned in fee simple by a concessioner or owned in fee simple by a concessioner's predecessor before the...

  3. 75 FR 67632 - Defense Federal Acquisition Regulation Supplement; Prohibition on Interrogation of Detainees by...

    Science.gov (United States)

    2010-11-03

    ...-AG88 Defense Federal Acquisition Regulation Supplement; Prohibition on Interrogation of Detainees by... National Defense Authorization Act for Fiscal Year 2010 (Pub. L. 111-84) prohibits the interrogation of..., to add DFARS 237.173, Prohibition on Interrogation of Detainees by Contractor Personnel, adding a...

  4. 12 CFR 4.37 - Persons and entities with access to OCC information; prohibition on dissemination.

    Science.gov (United States)

    2010-01-01

    ... information; prohibition on dissemination. 4.37 Section 4.37 Banks and Banking COMPTROLLER OF THE CURRENCY... § 4.37 Persons and entities with access to OCC information; prohibition on dissemination. (a) Current... agreement to abide by, the prohibition on the dissemination of non-public OCC information contained in...

  5. The role of social cost-benefit analysis in societal decision-making under large uncertainties with application to robbery at a cash depot

    International Nuclear Information System (INIS)

    Jones-Lee, M.; Aven, T.

    2009-01-01

    Social cost-benefit analysis is a well-established method for guiding decisions about safety investments, particularly in situations in which it is possible to make accurate predictions of future performance. However, its direct applicability to situations involving large degrees of uncertainty is less obvious and this raises the question of the extent to which social cost-benefit analysis can provide a useful input to the decision framework that has been explicitly developed to deal with safety decisions in which uncertainty is a major factor, namely risk analysis. This is the main focus of the arguments developed in this paper. In particular, we provide new insights by examining the fundamentals of both approaches and our principal conclusion is that social cost-benefit analysis and risk analysis represent complementary input bases to the decision-making process, and even in the case of large uncertainties social cost-benefit analysis may provide very useful decision support. What is required is the establishment of a proper contextual framework which structures and gives adequate weight to the uncertainties. An application to the possibility of a robbery at a cash depot is examined as a practical example.

  6. A periodic review integrated inventory model with controllable safety stock and setup cost under service level constraint and distribution-free demand

    Science.gov (United States)

    Kurdhi, N. A.; Jamaluddin, A.; Jauhari, W. A.; Saputro, D. R. S.

    2017-06-01

    In this study, we consider a stochastic integrated manufacturer-retailer inventory model with service level constraint. The model analyzed in this article considers the situation in which the vendor and the buyer establish a long-term contract and strategic partnership to jointly determine the best strategy. The lead time and setup cost are assumed can be controlled by an additional crashing cost and an investment, respectively. It is assumed that shortages are allowed and partially backlogged on the buyer’s side, and that the protection interval (i.e., review period plus lead time) demand distribution is unknown but has given finite first and second moments. The objective is to apply the minmax distribution free approach to simultaneously optimize the review period, the lead time, the setup cost, the safety factor, and the number of deliveries in order to minimize the joint total expected annual cost. The service level constraint guarantees that the service level requirement can be satisfied at the worst case. By constructing Lagrange function, the analysis regarding the solution procedure is conducted, and a solution algorithm is then developed. Moreover, a numerical example and sensitivity analysis are given to illustrate the proposed model and to provide some observations and managerial implications.

  7. NOTES ON ARBITRABILITY UNDER ETHIOPIAN LAW Introduction ...

    African Journals Online (AJOL)

    eliasn

    highlight the conceptual underpinnings of arbitrability in general and its treatment under Ethiopian ... not arbitrable under the law of the country where enforcement is sought.”3. ♧ .... general contract provisions concerning arbitration. When parties .... principle that “anything that is not prohibited is presumed to be permitted”,.

  8. [Revenue and losses with vertebral augmentation under the G-DRG system 2012 - a comparison of supply costs in the context of vertebroplasty and kyphoplasty].

    Science.gov (United States)

    Krüger, A; Wollny, M; Oberkircher, L; Bornemann, R; Pflugmacher, R

    2012-10-01

    If clearly indicated and implemented, augmentations of vertebral bodies with cement are standardized, safe and low-risk procedures. However, the multiplicity of providers and systems are today more varied than ever. At present, the systems differ starkly from one another not only in specifications, possible applications and extensions of indications, but they are also extremely variable in price. Publications have shown that in times of medical-economic change, vertebral augmentations make sense not only medically, but also in terms of economics and the national economy. Our analysis targets the question of how insurance costs with vertebroplasty and kyphoplasty affect profit margins per G-DRG (German Diagnosis Related Groups) in consideration of the different system approaches of the providers. After reviewing the literature, extremely varied, minimally invasive augmentation methods and techniques for treating vertebral body fractures were identified and classified. These were grouped based also [sic: on] OPS and possibly further subdivisions. Material costs were gathered based on average price quotations of different providers and techniques and aligned with those from the literature. The inpatient costs per day were estimated as a lump sum according to published information, since our analysis was interested in less detailed process costs as these are difficult to transfer to other clinics due to parameters being unique to each facility. The G-DRGs concerned were likewise determined according to the case-based lump sum catalogue from 2012. Based on this, the material costs as well as the daily costs per day of inpatient stay according to the average length of stay per G-DRG were subtracted. Vertebral augmentation methods are classified into vertebroplasty and kyphoplasty according to OPS. In addition, according to current literature, a further subdivision of kyphoplasty into substance-conserving or direct cement injection techniques and substance-destroying or

  9. [Cost effectiveness of workplace smoking policies].

    Science.gov (United States)

    Raaijmakers, Tamara; van den Borne, Inge

    2003-01-01

    This study reviews the motivations of companies to set out a policy for controlling smoking, the economic benefits for the company resulting from such a policy and the costs, broken down by European Union countries. The literature on the costs of implementing a policy related to smoking at the workplace is reviewed. The main objective of policies related to smoking at the workplace is that of safeguarding employees from environmental tobacco smoke. Other reasons are cutting costs, improving the company image, and reducing absenteeism, occupational accidents, internal quarrels and extra costs due to cigarette smoking, protection against environmental tobacco smoke does not entail any higher costs for companies, and economic advantages are visible. The benefits are by far greater than the costs involved, particularly on a long-range basis, and seem to be greater when smoking at the workplace is completely prohibited and no smoking areas are set.

  10. Permissions and Prohibitions in Data Protection Jurisdiction

    NARCIS (Netherlands)

    Taylor, M.S.C.

    Under public international law, a State has a right to exercise jurisdiction and is expected to show restraint when applying extraterritorial jurisdiction. The EU’s Data Protection Directive is far-reaching and has notable effects beyond its territory. The General Data Protection Regulation could

  11. 5 CFR 5801.102 - Prohibited securities.

    Science.gov (United States)

    2010-01-01

    ... securities list as a result of marriage, inheritance, gift or otherwise without specific intent to acquire..., which is available in the NRC Public Document Room. (6) Tax treatment of gain on divested securities... employee) may be eligible to defer the tax consequences of divestiture under subpart J of 5 CFR part 2634...

  12. 50 CFR 300.117 - Prohibitions.

    Science.gov (United States)

    2010-10-01

    ... States under Article IX of the Convention. (d) Ship, transport, offer for sale, sell, purchase, import..., harass, bribe, or interfere with an observer. (v) Interfere with or bias the sampling procedure employed... permit required by this subpart. (hh) Ship, transport, offer for sale, sell, purchase, import, export, re...

  13. 50 CFR 300.66 - Prohibitions.

    Science.gov (United States)

    2010-10-01

    ... accordance with the annual management measures published pursuant to 50 CFR 300.62. (b) Fish for halibut except in accordance with the catch sharing plans and domestic management measures implemented under 50... while commercial fishing or from sport fishing, as defined at § 300.61, except that persons authorized...

  14. 75 FR 67657 - Prohibition of Market Manipulation

    Science.gov (United States)

    2010-11-03

    ... negligence, will not satisfy the scienter requirement under Exchange Act section 10(b) and SEC Rule 10b- 5.... CFTC, 850 F.2d at 742, 748 (DC Cir. 1988) (``mere negligence, mistake, or inadvertence fails to meet [CEA] section 4b's scienter requirement * * * a degree of intent beyond carelessness or negligence'' is...

  15. 22 CFR 209.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-04-01

    ... participate in a program as an employee where a primary objective of the Federal financial assistance is to... subjected to discrimination under, any program or activity receiving Federal financial assistance from the... accomplishment of the objectives of the program as respects individuals of a particular race, color, or national...

  16. 15 CFR 8.4 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... (including the opportunity to participate in the program as an employee but only to the extent set forth in... defeating or substantially impairing accomplishment of the objectives of the program as respect any persons... provided under a program receiving Federal financial assistance shall be deemed to include any service...

  17. 43 CFR 17.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... participate in the program as an employee but only to the extent set forth in paragraph (c) of this section... impairing accomplishment of the objectives of the program as respect individuals of a particular race, color..., financial aid, or other benefits provided under a program receiving Federal financial assistance shall be...

  18. 45 CFR 611.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-10-01

    ... participate in the program of an employee but only to the extent set forth in paragraph (c) of this section... objectives of the program as respects individuals of a particular race, color, or national origin. (3) In... benefits provided under a program receiving Federal financial assistance shall be deemed to include any...

  19. Consumption and cost of diesel oil on cultivation of Zoysiagrass (Zoysia japonica Steud.) irrigated by aspersion canyons under two irrigation handlings

    Energy Technology Data Exchange (ETDEWEB)

    Mazaroni, Bruno Henrique Silveira; Turco, Jose Eduardo Pitelli; Coan, Ruchele Marchiori; Gerolineto, Eduardo [Universidade Estadual Paulista (FCAV/UNESP), Jaboticabal, SP (Brazil). Fac. de Ciencias Agrarias e Veterinarias

    2008-07-01

    This work aim to analyse the consumption and cost of diesel oil on cultivation of zoysiagrass (Zoysia japonica Steud.) irrigated by aspersion canyon, submitted of to two irrigation handling: T1 - irrigated when the tensiometer reading is equal - 0,5 atmospheres and T2 - irrigated by grass growers methodology. The research was carried on Green-Park Farm, in the city of Pitangueiras, SP. Consumption of diesel oil was measured from a diesel engine, brand MWM, turbined with 6 cylinders, type D-229 for zoysiagrass production. The diesel price was gotten from Petroleum National Agency (ANP), being an average price in Sao Paulo State, in February 2007, converted into the commercial dollar. Economical result was studied, subtracting the selling value of the grass, by the cost of the fuel consumed, for both T1 and T2 treatments. The treatment made by tensiometer showed greater diesel consumption, related to treatment T2, where the handling was made by the grass grower. (author)

  20. Parametric optimization for the low cost production of nanostructure ...

    African Journals Online (AJOL)

    In recent years, nanocrystalline materials have drawn the attention of researchers in the field of materials science engineering due to its enhanced mechanical properties such as high strength and high hardness. However, the cost of nanocrystalline materials is prohibitively high, primarily due to the expensive equipments ...