WorldWideScience

Sample records for twenty-six descriptors covering

  1. Effects of energy constraints on transportation systems. [Twenty-six papers

    Energy Technology Data Exchange (ETDEWEB)

    Mittal, R. K. [ed.

    1977-12-01

    Twenty-six papers are presented on a variety of topics including: energy and transportaton facts and figures; long-range planning under energy constraints; technology assessment of alternative fuels; energy efficiency of intercity passenger and freight movement; energy efficiency of intracity passenger movement; federal role; electrification of railroads; energy impact of the electric car in an urban enviroment; research needs and projects in progress--federal viewpoint; research needs in transportation energy conservation--data needs; and energy intensity of various transportation modes--an overview. A separate abstract was prepared for each of the papers for inclusion in Energy Research Abstracts (ERA) and in Energy Abstracts for Policy Analysis (EAPA).

  2. Surgical treatment of pelvic sarcoma in children: outcomes for twenty six patients.

    Science.gov (United States)

    Kadhim, Muayad; Womer, Richard B; Dormans, John P

    2017-07-27

    Pelvic sarcoma is uncommon in children and challenging to treat. This study examined different surgical approaches to treat pelvic sarcoma with the aim of assessing the oncologic, and functional outcomes. We retrospectively examined the medical records of patients younger than 21 years of age who underwent surgery for pelvic sarcoma at our institution from 1992 to 2010. The functional status of the patients was examined after a minimum follow-up of two years. Twenty-six patients were included in the analysis. Nineteen (73%) patients were male and seven (27%) were female. Mean age at presentation was 12.0 ± 3.9 years. Nineteen patients had Ewing sarcoma (73%), five had osteosarcoma (19%), one had chondrosarcoma (4%) and one had rhabdomyosarcoma (4%). Iliac wing resection with no reconstruction was done in three patients. Reconstruction with free fibular graft A-frame was performed in four patients, saddle endoproshtesis in five patients, iliac autoclave in one patient, and internal hemipelvectomy in nine patients. Hindquarter amputation was performed in five patients. Median follow-up was 4.6 years (range, 2.6-16 years). Nineteen patients were alive (73%); of those, 13 were known to be without disease, three were with disease and three did not have known tumor status. Six patients were reported deceased, three had osteosarcoma and three had Ewing sarcoma. Function was assessed in 17 patients; 64% were asymptomatic and ambulatory and 36% were symptomatic and ambulatory. Salvage reconstruction for pelvic sarcoma can be performed through various procedures on the extent of necessary bony resection. Survival rate and functional outcomes were promising in the performed study.

  3. Twenty-six years of HIV science: an overview of anti-HIV drugs metabolism

    Directory of Open Access Journals (Sweden)

    Carolina Horta Andrade

    2011-06-01

    Full Text Available From the identification of HIV as the agent causing AIDS, to the development of effective antiretroviral drugs, the scientific achievements in HIV research over the past twenty-six years have been formidable. Currently, there are twenty-five anti-HIV compounds which have been formally approved for clinical use in the treatment of AIDS. These compounds fall into six categories: nucleoside reverse transcriptase inhibitors (NRTIs, nucleotide reverse transcriptase inhibitors (NtRTIs, non-nucleoside reverse transcriptase inhibitors (NNRTIs, protease inhibitors (PIs, cell entry inhibitors or fusion inhibitors (FIs, co-receptor inhibitors (CRIs, and integrase inhibitors (INIs. Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. Formation of active or toxic metabolites will also have an impact on the pharmacological and toxicological outcomes. Therefore, it is widely recognized that metabolism studies of a new chemical entity need to be addressed early in the drug discovery process. This paper describes an overview of the metabolism of currently available anti-HIV drugs.Da identificação do HIV como o agente causador da AIDS, ao desenvolvimento de fármacos antirretrovirais eficazes, os avanços científicos na pesquisa sobre o HIV nos últimos vinte e seis anos foram marcantes. Atualmente, existem vinte e cinco fármacos anti-HIV formalmente aprovados pelo FDA para utilização clínica no tratamento da AIDS. Estes compostos são divididos em seis classes: inibidores nucleosídeos de transcriptase reversa (INTR, inibidores nucleotídeos de transcriptase reversa (INtTR, inibidores não-nucleosídeos de transcriptase reversa (INNTR, inibidores de protease (IP, inibidores da entrada celular ou inibidores de fusão (IF, inibidores de co-receptores (ICR e inibidores de integrase (INI. O metabolismo consiste em um dos maiores determinantes do perfil farmacocinético de um fármaco. A forma

  4. Module descriptor

    DEFF Research Database (Denmark)

    Vincenti, Gordon; Klausen, Bodil; Kjær Jensen, Jesper

    2016-01-01

    The Module Descriptor including a Teacher’s Guide explains and describes how to work innovatively and co-creatively with wicked problems and young people. The descriptor shows how interested educators and lecturers in Europe can copy the lessons of the Erasmus+ project HIP when teaching their own...... students how to include marginalized young people and practitioners in the education of future social workers and social educators....

  5. Module descriptor

    DEFF Research Database (Denmark)

    Vincenti, Gordon; Klausen, Bodil; Kjær Jensen, Jesper

    2016-01-01

    The Module Descriptor including a Teacher’s Guide explains and describes how to work innovatively and co-creatively with wicked problems and young people. The descriptor shows how interested educators and lecturers in Europe can copy the lessons of the Erasmus+ project HIP when teaching their own...... students how to include marginalized young people and practitioners in the education of future social workers and social educators....

  6. Chapter Twenty Six

    African Journals Online (AJOL)

    User

    wisdom, that is, the results of human efforts to understand life and the ... Some of the characteristics of Hebrew poetry include parallelism, figurative language, .... each line in these 3 verses is really saying the same thing in a repetitive fashion.

  7. CTD cast and zooplankton count data collected in Dabob Bay, Hood Canal, Puget Sound, Washington during twenty-six cruises aboard the CLIFFORD A. BARNES, February 2002 - April 2004 (NODC Accession 0014832)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains CTD cast and zooplankton data collected during twenty-six cruises to Dabob Bay, Washington in 2002 - 2004 for the project entitled "Copepod -...

  8. Topological Substituent Descriptors

    Directory of Open Access Journals (Sweden)

    Mircea V. DIUDEA

    2002-12-01

    Full Text Available Motivation. Substituted 1,3,5-triazines are known as useful herbicidal substances. In view of reducing the cost of biological screening, computational methods are carried out for evaluating the biological activity of organic compounds. Often a class of bioactives differs only in the substituent attached to a basic skeleton. In such cases substituent descriptors will give the same prospecting results as in case of using the whole molecule description, but with significantly reduced computational time. Such descriptors are useful in describing steric effects involved in chemical reactions. Method. Molecular topology is the method used for substituent description and multi linear regression analysis as a statistical tool. Results. Novel topological descriptors, XLDS and Ws, based on the layer matrix of distance sums and walks in molecular graphs, respectively, are proposed for describing the topology of substituents linked on a chemical skeleton. They are tested for modeling the esterification reaction in the class of benzoic acids and herbicidal activity of 2-difluoromethylthio-4,6-bis(monoalkylamino-1,3,5-triazines. Conclusions. Ws substituent descriptor, based on walks in graph, satisfactorily describes the steric effect of alkyl substituents behaving in esterification reaction, with good correlations to the Taft and Charton steric parameters, respectively. Modeling the herbicidal activity of the seo of 1,3,5-triazines exceeded the models reported in literature, so far.

  9. The FREPA Descriptors

    DEFF Research Database (Denmark)

    Daryai-Hansen, Petra; Jaeger, Catherine

    2015-01-01

    to the Common European Framework of Reference for Languages, specifying in detail and structuring its rationale on intercultural and plurilingual competences. The FREPA tools consist of (a) a comprehensive list of descriptors operationalizing intercultural and plurilingual competences in terms of knowledge......, attitudes and skills, (b) a database of teaching material and (c) a training kit for teachers. The paper presents the FREPA descriptors by comparing them to Byram’s definition of intercultural communicative competence and Deardorff’s intercultural competence model and emphasises that FREPA deepens...... and complements Byram’s and Deardorff’s approaches through its distinction between competences and resources, the finely scaled catalogue of subdescriptors, the integration of plurilingual competences, and the establishment of learning to learn as a transversal dimension. Finally, the paper illustrates...

  10. The FREPA Descriptors

    DEFF Research Database (Denmark)

    Daryai-Hansen, Petra; Jaeger, Catherine

    2015-01-01

    to the Common European Framework of Reference for Languages, specifying in detail and structuring its rationale on intercultural and plurilingual competences. The FREPA tools consist of (a) a comprehensive list of descriptors operationalizing intercultural and plurilingual competences in terms of knowledge......The paper discusses a set of tools that have been developed within the FREPA research project, supported since 2004 by the Council of Europe’s European Centre for Modern Languages. The Framework of Reference for Pluralistic Approaches to Languages and Cultures (FREPA) represents a complement...

  11. Descriptors for antimicrobial peptides

    DEFF Research Database (Denmark)

    Jenssen, Håvard

    2011-01-01

    Introduction: A frightening increase in the number of isolated multidrug resistant bacterial strains linked to the decline in novel antimicrobial drugs entering the market is a great cause for concern. Cationic antimicrobial peptides (AMPs) have lately been introduced as a potential new class...... examples of different peptide QSAR studies, this review highlights some of the missing links and illuminates some of the questions that would be interesting to challenge in a more systematic fashion. Expert opinion: Computer-aided peptide QSAR using molecular descriptors may provide the necessary edge...

  12. The FREPA Descriptors

    DEFF Research Database (Denmark)

    Daryai-Hansen, Petra; Jaeger, Catherine

    2015-01-01

    The paper discusses a set of tools that have been developed within the FREPA research project, supported since 2004 by the Council of Europe’s European Centre for Modern Languages. The Framework of Reference for Pluralistic Approaches to Languages and Cultures (FREPA) represents a complement......, attitudes and skills, (b) a database of teaching material and (c) a training kit for teachers. The paper presents the FREPA descriptors by comparing them to Byram’s definition of intercultural communicative competence and Deardorff’s intercultural competence model and emphasises that FREPA deepens...

  13. Separability of local reactivity descriptors

    Indian Academy of Sciences (India)

    Akhilesh Tanwar; Sourav Pal

    2005-09-01

    The size-dependence of different local reactivity descriptors of dimer A2 and AB type of systems is discussed. We derive analytic results of these descriptors calculated using finite difference approximation. In particular, we studied Fukui functions, relative electrophilicity and relative nucleophilicity, local softness and local philicity. The results are explained using the example of the dimer of BH3NH3.

  14. OCWLGI descriptors: theory and praxis.

    Science.gov (United States)

    Toropov, Andrey A; Toropova, Alla P; Benfenati, Emilio; Gini, Giuseppina

    2013-06-01

    The aim of this review is description of the logic and evolution of optimal descriptors OCWLGI calculated with the molecular graph and the demonstration of their ability as tools for the modeling of biological and physicochemical parameters of chemical compounds. The ability of optimal descriptors calculated with hydrogen suppressed graph (HSG), hydrogen filled graph (HFG) and graph of atomic orbitals (GAO) is demonstrated as a collection of quantitative structure-property relationships (QSPR) and quantitative structure-activity relationships (QSAR) for properties and endpoints available from the literature. The Monte Carlo method optimization of the correlation weights of local and global invariants (OCWLGI) of molecular graphs is used as the principle for building up descriptors which are discussed in this article. The statistical quality of the QSPR and QSAR models for physicochemical and biological properties which were obtained with the optimal descriptors are reasonably high.

  15. FEATURE DESCRIPTOR BY CONVOLUTION AND POOLING AUTOENCODERS

    Directory of Open Access Journals (Sweden)

    L. Chen

    2015-03-01

    Full Text Available In this paper we present several descriptors for feature-based matching based on autoencoders, and we evaluate the performance of these descriptors. In a training phase, we learn autoencoders from image patches extracted in local windows surrounding key points determined by the Difference of Gaussian extractor. In the matching phase, we construct key point descriptors based on the learned autoencoders, and we use these descriptors as the basis for local keypoint descriptor matching. Three types of descriptors based on autoencoders are presented. To evaluate the performance of these descriptors, recall and 1-precision curves are generated for different kinds of transformations, e.g. zoom and rotation, viewpoint change, using a standard benchmark data set. We compare the performance of these descriptors with the one achieved for SIFT. Early results presented in this paper show that, whereas SIFT in general performs better than the new descriptors, the descriptors based on autoencoders show some potential for feature based matching.

  16. Jet-Based Local Image Descriptors

    DEFF Research Database (Denmark)

    Larsen, Anders Boesen Lindbo; Darkner, Sune; Dahl, Anders Lindbjerg;

    2012-01-01

    We present a general novel image descriptor based on higherorder differential geometry and investigate the effect of common descriptor choices. Our investigation is twofold in that we develop a jet-based descriptor and perform a comparative evaluation with current state-of-the-art descriptors on ....... We show that the proposed jet-based descriptor is superior to state-of-the-art for DoG interest points and show competitive performance for the other tested interest points....

  17. Image feature detectors and descriptors foundations and applications

    CERN Document Server

    Hassaballah, Mahmoud

    2016-01-01

    This book provides readers with a selection of high-quality chapters that cover both theoretical concepts and practical applications of image feature detectors and descriptors. It serves as reference for researchers and practitioners by featuring survey chapters and research contributions on image feature detectors and descriptors. Additionally, it emphasizes several keywords in both theoretical and practical aspects of image feature extraction. The keywords include acceleration of feature detection and extraction, hardware implantations, image segmentation, evolutionary algorithm, ordinal measures, as well as visual speech recognition. .

  18. Jet-Based Local Image Descriptors

    DEFF Research Database (Denmark)

    Larsen, Anders Boesen Lindbo; Darkner, Sune; Dahl, Anders Lindbjerg;

    2012-01-01

    We present a general novel image descriptor based on higherorder differential geometry and investigate the effect of common descriptor choices. Our investigation is twofold in that we develop a jet-based descriptor and perform a comparative evaluation with current state-of-the-art descriptors...... on the recently released DTU Robot dataset. We demonstrate how the use of higher-order image structures enables us to reduce the descriptor dimensionality while still achieving very good performance. The descriptors are tested in a variety of scenarios including large changes in scale, viewing angle and lighting...

  19. Molecular quantum similarity using conceptual DFT descriptors

    Indian Academy of Sciences (India)

    Patrick Bultinck; Ramon carbó-dorca

    2005-09-01

    This paper reports a Molecular Quantum Similarity study for a set of congeneric steroid molecules, using as basic similarity descriptors electron density ρ (r), shape function (r), the Fukui functions +(r) and -(r) and local softness +(r) and -(r). Correlations are investigated between similarity indices for each couple of descriptors used and compared to assess whether these different descriptors sample different information and to investigate what information is revealed by each descriptor.

  20. Genetic predisposition to obesity and lifestyle factors--the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study.

    Science.gov (United States)

    Jääskeläinen, Tiina; Paananen, Jussi; Lindström, Jaana; Eriksson, Johan G; Tuomilehto, Jaakko; Uusitupa, Matti

    2013-11-01

    Recent genome-wide association studies have identified multiple loci associated with BMI or the waist:hip ratio (WHR). However, evidence on gene-lifestyle interactions is still scarce, and investigation of the effects of well-documented dietary and other lifestyle data is warranted to assess whether genetic risk can be modified by lifestyle. We assessed whether previously established BMI and WHR genetic variants associate with obesity and weight change in the Finnish Diabetes Prevention Study, and whether the associations are modified by dietary factors or physical activity. Individuals (n 459) completed a 3 d food record and were genotyped for twenty-six BMI- and fourteen WHR-related variants. The effects of the variants individually and in combination were investigated in relation to obesity and to 1- and 3-year weight change by calculating genetic risk scores (GRS). The GRS were separately calculated for BMI and the WHR by summing the increasing alleles weighted by their published effect sizes. At baseline, the GRS were not associated with total intakes of energy, macronutrients or fibre. The mean 1- and 3-year weight changes were not affected by the BMI or WHR GRS. During the 3-year follow-up, a trend for higher BMI by the GRS was detected especially in those who reported a diet low in fibre (P for interaction=0·065). Based on the present findings, it appears unlikely that obesity-predisposing variants substantially modify the effect of lifestyle modification on the success of weight reduction in the long term. In addition, these findings suggest that the association between the BMI-related genetic variants and obesity could be modulated by the diet.

  1. Robust control of linear descriptor systems

    CERN Document Server

    Feng, Yu

    2017-01-01

    This book develops original results regarding singular dynamic systems following two different paths. The first consists of generalizing results from classical state-space cases to linear descriptor systems, such as dilated linear matrix inequality (LMI) characterizations for descriptor systems and performance control under regulation constraints. The second is a new path, which considers descriptor systems as a powerful tool for conceiving new control laws, understanding and deciphering some controller’s architecture and even homogenizing different—existing—ways of obtaining some new and/or known results for state-space systems. The book also highlights the comprehensive control problem for descriptor systems as an example of using the descriptor framework in order to transform a non-standard control problem into a classic stabilization control problem. In another section, an accurate solution is derived for the sensitivity constrained linear optimal control also using the descriptor framework. The boo...

  2. Descriptors of server capabilities in China

    DEFF Research Database (Denmark)

    Adeyemi, Oluseyi; Slepniov, Dmitrij; Wæhrens, Brian Vejrum

    2013-01-01

    China with the huge market potential it possesses is an important issue for subsidiaries of western multinational companies. The objective of this paper is therefore to strengthen researchers’ and practitioners’ perspectives on what are the descriptors of server capabilities. The descriptors...... are relevant to determine subsidiary roles and as an indication of the capabilities required. These descriptors are identified through extensive literature review and validated by case studies of two Danish multinational companies subsidiaries operating in China. They provided the empirical basis...

  3. Control Configuration Selection for Multivariable Descriptor Systems

    DEFF Research Database (Denmark)

    Shaker, Hamid Reza; Stoustrup, Jakob

    2012-01-01

    is needed to be controlled, is either in the descriptor form or can be represented in the descriptor form. Singular systems and the differential algebraic equation (DAE) systems are among these systems. Descriptor systems appear in the variety of fields to describe the practical processes ranging from power...... systems, hydraulic systems to heat transfer, and chemical processes. The focus of this paper is on the problem of control configuration selection for multivariable descriptor systems. A gramian-based interaction measure for control configuration selection of such processes is described in this paper...

  4. In Silico Design in Homogeneous Catalysis Using Descriptor Modelling

    Directory of Open Access Journals (Sweden)

    Gadi Rothenberg

    2006-09-01

    Full Text Available This review summarises the state-of-the-art methodologies used for designinghomogeneous catalysts and optimising reaction conditions (e.g. choosing the right solvent.We focus on computational techniques that can complement the current advances in high-throughput experimentation, covering the literature in the period 1996-2006. The reviewassesses the use of molecular modelling tools, from descriptor models based onsemiempirical and molecular mechanics calculations, to 2D topological descriptors andgraph theory methods. Different techniques are compared based on their computational andtime cost, output level, problem relevance and viability. We also review the application ofvarious data mining tools, including artificial neural networks, linear regression, andclassification trees. The future of homogeneous catalysis discovery and optimisation isdiscussed in the light of these developments.

  5. Video summarization using motion descriptors

    Science.gov (United States)

    Divakaran, Ajay; Peker, Kadir A.; Sun, Huifang

    2001-01-01

    We describe a technique for video summarization that uses motion descriptors computed in the compressed domain to speed up conventional color based video summarization technique. The basic hypothesis of the work is that the intensity of motion activity of a video segment is a direct indication of its 'summarizability.' We present experimental verification of this hypothesis. We are thus able to quickly identify easy to summarize segments of a video sequence since they have a low intensity of motion activity. Moreover, the compressed domain extraction of motion activity intensity is much simpler than the color-based calculations. We are able to easily summarize these segments by simply choosing a key-frame at random from each low- activity segment. We can then apply conventional color-based summarization techniques to the remaining segments. We are thus able to speed up color-based summarization techniques by reducing the number of segments on which computationally more expensive color-based computation is needed.

  6. Density-Based 3D Shape Descriptors

    Directory of Open Access Journals (Sweden)

    Schmitt Francis

    2007-01-01

    Full Text Available We propose a novel probabilistic framework for the extraction of density-based 3D shape descriptors using kernel density estimation. Our descriptors are derived from the probability density functions (pdf of local surface features characterizing the 3D object geometry. Assuming that the shape of the 3D object is represented as a mesh consisting of triangles with arbitrary size and shape, we provide efficient means to approximate the moments of geometric features on a triangle basis. Our framework produces a number of 3D shape descriptors that prove to be quite discriminative in retrieval applications. We test our descriptors and compare them with several other histogram-based methods on two 3D model databases, Princeton Shape Benchmark and Sculpteur, which are fundamentally different in semantic content and mesh quality. Experimental results show that our methodology not only improves the performance of existing descriptors, but also provides a rigorous framework to advance and to test new ones.

  7. Determination of solute descriptors by chromatographic methods

    Energy Technology Data Exchange (ETDEWEB)

    Poole, Colin F., E-mail: cfp@chem.wayne.edu [Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States); Atapattu, Sanka N.; Poole, Salwa K.; Bell, Andrea K. [Department of Chemistry, Wayne State University, Detroit, MI 48202 (United States)

    2009-10-12

    The solvation parameter model is now well established as a useful tool for obtaining quantitative structure-property relationships for chemical, biomedical and environmental processes. The model correlates a free-energy related property of a system to six free-energy derived descriptors describing molecular properties. These molecular descriptors are defined as L (gas-liquid partition coefficient on hexadecane at 298 K), V (McGowan's characteristic volume), E (excess molar refraction), S (dipolarity/polarizability), A (hydrogen-bond acidity), and B (hydrogen-bond basicity). McGowan's characteristic volume is trivially calculated from structure and the excess molar refraction can be calculated for liquids from their refractive index and easily estimated for solids. The remaining four descriptors are derived by experiment using (largely) two-phase partitioning, chromatography, and solubility measurements. In this article, the use of gas chromatography, reversed-phase liquid chromatography, micellar electrokinetic chromatography, and two-phase partitioning for determining solute descriptors is described. A large database of experimental retention factors and partition coefficients is constructed after first applying selection tools to remove unreliable experimental values and an optimized collection of varied compounds with descriptor values suitable for calibrating chromatographic systems is presented. These optimized descriptors are demonstrated to be robust and more suitable than other groups of descriptors characterizing the separation properties of chromatographic systems.

  8. Correlation of Lipophilicity Descriptors with Pharmacokinetic ...

    African Journals Online (AJOL)

    Dr Olaleye

    1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria. ... plasma concentration (Tmax) and area under plasma concentration – time curve (AUC), using ..... molecular descriptors: A critical review.

  9. Feature point descriptors: infrared and visible spectra

    National Research Council Canada - National Science Library

    Ricaurte, Pablo; Chilán, Carmen; Aguilera-Carrasco, Cristhian A; Vintimilla, Boris X; Sappa, Angel D

    2014-01-01

    This manuscript evaluates the behavior of classical feature point descriptors when they are used in images from long-wave infrared spectral band and compare them with the results obtained in the visible spectrum...

  10. A Descriptor Systems Toolbox for MATLAB

    OpenAIRE

    Varga, A

    2000-01-01

    We describe a recently developed DESCRIPTOR SYSTEMS Toolbox implemented under MATLAB. This Toolbox relies on the object oriented approach for control systems analysis and design provided within the standard CONTROL Toolbox of MATLAB. The basic approach to develop the DESCRIPTOR SYSTEMS Toolbox was to exploit the powerful matrix and system object manipulation features of MATLAB via flexible and functionally rich high level m-functions, while simultaneously enforcing highly efficient and numeri...

  11. Signature molecular descriptor : advanced applications.

    Energy Technology Data Exchange (ETDEWEB)

    Visco, Donald Patrick, Jr. (Tennessee Technological University, Cookeville, TN)

    2010-04-01

    In this work we report on the development of the Signature Molecular Descriptor (or Signature) for use in the solution of inverse design problems as well as in highthroughput screening applications. The ultimate goal of using Signature is to identify novel and non-intuitive chemical structures with optimal predicted properties for a given application. We demonstrate this in three studies: green solvent design, glucocorticoid receptor ligand design and the design of inhibitors for Factor XIa. In many areas of engineering, compounds are designed and/or modified in incremental ways which rely upon heuristics or institutional knowledge. Often multiple experiments are performed and the optimal compound is identified in this brute-force fashion. Perhaps a traditional chemical scaffold is identified and movement of a substituent group around a ring constitutes the whole of the design process. Also notably, a chemical being evaluated in one area might demonstrate properties very attractive in another area and serendipity was the mechanism for solution. In contrast to such approaches, computer-aided molecular design (CAMD) looks to encompass both experimental and heuristic-based knowledge into a strategy that will design a molecule on a computer to meet a given target. Depending on the algorithm employed, the molecule which is designed might be quite novel (re: no CAS registration number) and/or non-intuitive relative to what is known about the problem at hand. While CAMD is a fairly recent strategy (dating to the early 1980s), it contains a variety of bottlenecks and limitations which have prevented the technique from garnering more attention in the academic, governmental and industrial institutions. A main reason for this is how the molecules are described in the computer. This step can control how models are developed for the properties of interest on a given problem as well as how to go from an output of the algorithm to an actual chemical structure. This report

  12. Stargate GTM: Bridging Descriptor and Activity Spaces.

    Science.gov (United States)

    Gaspar, Héléna A; Baskin, Igor I; Marcou, Gilles; Horvath, Dragos; Varnek, Alexandre

    2015-11-23

    Predicting the activity profile of a molecule or discovering structures possessing a specific activity profile are two important goals in chemoinformatics, which could be achieved by bridging activity and molecular descriptor spaces. In this paper, we introduce the "Stargate" version of the Generative Topographic Mapping approach (S-GTM) in which two different multidimensional spaces (e.g., structural descriptor space and activity space) are linked through a common 2D latent space. In the S-GTM algorithm, the manifolds are trained simultaneously in two initial spaces using the probabilities in the 2D latent space calculated as a weighted geometric mean of probability distributions in both spaces. S-GTM has the following interesting features: (1) activities are involved during the training procedure; therefore, the method is supervised, unlike conventional GTM; (2) using molecular descriptors of a given compound as input, the model predicts a whole activity profile, and (3) using an activity profile as input, areas populated by relevant chemical structures can be detected. To assess the performance of S-GTM prediction models, a descriptor space (ISIDA descriptors) of a set of 1325 GPCR ligands was related to a B-dimensional (B = 1 or 8) activity space corresponding to pKi values for eight different targets. S-GTM outperforms conventional GTM for individual activities and performs similarly to the Lasso multitask learning algorithm, although it is still slightly less accurate than the Random Forest method.

  13. 8th Workshop on Coupled Descriptor Systems

    CERN Document Server

    Bartel, Andreas; Günther, Michael; Maten, E; Müller, Peter

    2014-01-01

    This book contains the proceedings of the 8th Workshop on Coupled Descriptor Systems held March 2013 in the Castle of Eringerfeld, Geseke in the neighborhood of Paderborn, Germany. It examines the wide range of current research topics in descriptor systems, including mathematical modeling, index analysis, wellposedness of problems, stiffness and different time-scales, cosimulation and splitting methods and convergence analysis. In addition, the book also presents applications from the automotive and circuit industries that show that descriptor systems provide challenging problems from the point of view of both theory and practice.   The book contains nine papers and is organized into three parts: control, simulation, and model order reduction. It will serve as an ideal resource for applied mathematicians and engineers, in particular those from mechanics and electromagnetics, who work with coupled differential equations.

  14. Modular Chemical Descriptor Language (MCDL: Stereochemical modules

    Directory of Open Access Journals (Sweden)

    Gakh Andrei A

    2011-01-01

    Full Text Available Abstract Background In our previous papers we introduced the Modular Chemical Descriptor Language (MCDL for providing a linear representation of chemical information. A subsequent development was the MCDL Java Chemical Structure Editor which is capable of drawing chemical structures from linear representations and generating MCDL descriptors from structures. Results In this paper we present MCDL modules and accompanying software that incorporate unique representation of molecular stereochemistry based on Cahn-Ingold-Prelog and Fischer ideas in constructing stereoisomer descriptors. The paper also contains additional discussions regarding canonical representation of stereochemical isomers, and brief algorithm descriptions of the open source LINDES, Java applet, and Open Babel MCDL processing module software packages. Conclusions Testing of the upgraded MCDL Java Chemical Structure Editor on compounds taken from several large and diverse chemical databases demonstrated satisfactory performance for storage and processing of stereochemical information in MCDL format.

  15. Local Descriptors of Dynamic and Nondynamic Correlation.

    Science.gov (United States)

    Ramos-Cordoba, Eloy; Matito, Eduard

    2017-06-13

    Quantitatively accurate electronic structure calculations rely on the proper description of electron correlation. A judicious choice of the approximate quantum chemistry method depends upon the importance of dynamic and nondynamic correlation, which is usually assesed by scalar measures. Existing measures of electron correlation do not consider separately the regions of the Cartesian space where dynamic or nondynamic correlation are most important. We introduce real-space descriptors of dynamic and nondynamic electron correlation that admit orbital decomposition. Integration of the local descriptors yields global numbers that can be used to quantify dynamic and nondynamic correlation. Illustrative examples over different chemical systems with varying electron correlation regimes are used to demonstrate the capabilities of the local descriptors. Since the expressions only require orbitals and occupation numbers, they can be readily applied in the context of local correlation methods, hybrid methods, density matrix functional theory, and fractional-occupancy density functional theory.

  16. Replenishing data descriptors in a DMA injection FIFO buffer

    Science.gov (United States)

    Archer, Charles J [Rochester, MN; Blocksome, Michael A [Rochester, MN; Cernohous, Bob R [Rochester, MN; Heidelberger, Philip [Cortlandt Manor, NY; Kumar, Sameer [White Plains, NY; Parker, Jeffrey J [Rochester, MN

    2011-10-11

    Methods, apparatus, and products are disclosed for replenishing data descriptors in a Direct Memory Access (`DMA`) injection first-in-first-out (`FIFO`) buffer that include: determining, by a messaging module on an origin compute node, whether a number of data descriptors in a DMA injection FIFO buffer exceeds a predetermined threshold, each data descriptor specifying an application message for transmission to a target compute node; queuing, by the messaging module, a plurality of new data descriptors in a pending descriptor queue if the number of the data descriptors in the DMA injection FIFO buffer exceeds the predetermined threshold; establishing, by the messaging module, interrupt criteria that specify when to replenish the injection FIFO buffer with the plurality of new data descriptors in the pending descriptor queue; and injecting, by the messaging module, the plurality of new data descriptors into the injection FIFO buffer in dependence upon the interrupt criteria.

  17. Mammographic images segmentation using texture descriptors.

    Science.gov (United States)

    Mascaro, Angelica A; Mello, Carlos A B; Santos, Wellington P; Cavalcanti, George D C

    2009-01-01

    Tissue classification in mammography can help the diagnosis of breast cancer by separating healthy tissue from lesions. We present herein the use of three texture descriptors for breast tissue segmentation purposes: the Sum Histogram, the Gray Level Co-Occurrence Matrix (GLCM) and the Local Binary Pattern (LBP). A modification of the LBP is also proposed for a better distinction of the tissues. In order to segment the image into its tissues, these descriptors are compared using a fidelity index and two clustering algorithms: k-Means and SOM (Self-Organizing Maps).

  18. Analysis of activity space by fragment fingerprints, 2D descriptors, and multitarget dependent transformation of 2D descriptors.

    Science.gov (United States)

    Givehchi, Alireza; Bender, Andreas; Glen, Robert C

    2006-01-01

    The effect of multitarget dependent descriptor transformation on classification performance is explored in this work. To this end decision trees as well as neural net QSAR in combination with PLS were applied to predict the activity class of 5HT3 ligands, angiotensin converting enzyme inhibitors, 3-hydroxyl-3-methyl glutaryl coenzyme A reductase inhibitors, platelet activating factor antagonists, and thromboxane A2 antagonists. Physicochemical descriptors calculated by MOE and fragment-based descriptors (MOLPRINT 2D) were employed to generate descriptor vectors. In a subsequent step the physicochemical descriptor vectors were transformed to a lower dimensional space using multitarget dependent descriptor transformation. Cross-validation of the original physicochemical descriptors in combination with decision trees and neural net QSAR as well as cross-validation of PLS multitarget transformed descriptors with neural net QSAR were performed. For comparison this was repeated using fragment-based descriptors in combination with decision trees.

  19. Robustifying Descriptor Instability using Fisher Vectors

    NARCIS (Netherlands)

    I. Everts; J.C. van Gemert; T. Mensink; T. Gevers

    2014-01-01

    Many computer vision applications, including image classification, matching, and retrieval use global image representations, such as the Fisher vector, to encode a set of local image patches. To describe these patches, many local descriptors have been designed to be robust against lighting changes a

  20. A Comparison of 2-D Shape Retrieval Using Fourier Descriptors and Wavelet Descriptors

    Institute of Scientific and Technical Information of China (English)

    LIQin; JonathanEdwards

    2005-01-01

    Choosing an appropriate image retrieval tool is the primary problem for a multimedia application such as digital image library and online image retrieval. Shape is often regarded as the most important image feature. Fourier descriptors (FDs) are widely used in shape recognition and retrieval. However, as global descriptors, they are often blamed for not being able to describe local shape features[1,2]. Wavelet descriptors (WDs) are proposed to overcome this drawback. Unfortunately, the extra information such as the multi-resolution scheme and local shape features cause much more complicate shape matching algorithms. The efficient or effective use of WD srequires more effort. Experiments are executed to evaluate the retrieval performance of this two descriptors. Some conclusions and suggestions are given according to the experimental results and the literature reviewed.

  1. KW-SIFT descriptor for remote-sensing image registration

    Institute of Scientific and Technical Information of China (English)

    Xiangzeng Liu; Zheng Tian; Weidong Yan; Xifa Duan

    2011-01-01

    A technique to construct an affine invariant descriptor for remote-sensing image registration based on the scale invariant features transform (SIFT) in a kernel space is proposed.Affine invariant SIFT descriptor is first developed in an elliptical region determined by the Hessian matrix of the feature points.Thereafter,the descriptor is mapped to a feature space induced by a kernel, and a new descriptor is constructed by whitening the mapped descriptor in the feature space, with the transform called KW-SIFT.In a final step, the new descriptor is used to register remote-sensing images.Experimental results for remote-sensing image registration indicate that the proposed method improves the registration performance as compared with other related methods.%@@ A technique to construct an affine invariant descriptor for remote-sensing image registration based on the scale invariant features transform (SIFT) in a kernel space is proposed.Affine invariant SIFT descriptor is first developed in an elliptical region determined by the Hessian matrix of the feature points.Thereafter,the descriptor is mapped to a feature space induced by a kernel, and a new descriptor is constructed by whitening the mapped descriptor in the feature space, with the transform called KW-SIFT.In a final step, the new descriptor is used to register remote-sensing images.Experimental results for remote-sensing image registration indicate that the proposed method improves the registration performance as compared with other related methods.

  2. Ensembles of Novel Visual Keywords Descriptors for Image Categorization

    NARCIS (Netherlands)

    Abdullah, Azizi; Veltkamp, Remco C.; Wiering, Marco

    2010-01-01

    Object recognition systems need effective image descriptors to obtain good performance levels. Currently, the most widely used image descriptor is the SIFT descriptor that computes histograms of orientation gradients around points in an image. A possible problem of this approach is that the number

  3. Recognition of handwritten characters using local gradient feature descriptors

    NARCIS (Netherlands)

    Surinta, Olarik; Karaaba, Mahir F.; Schomaker, Lambert R.B.; Wiering, Marco A.

    2015-01-01

    Abstract In this paper we propose to use local gradient feature descriptors, namely the scale invariant feature transform keypoint descriptor and the histogram of oriented gradients, for handwritten character recognition. The local gradient feature descriptors are used to extract feature vectors fro

  4. Visual Descriptor Learning for Predicting Grasping Affordances

    DEFF Research Database (Denmark)

    Thomsen, Mikkel Tang

    2016-01-01

    consisting of surface features was performed. Dimensions in the visual space were varied and the effects were evaluated with the task of grasping unknown object. The evaluation was performed using a novel probabilistic grasp prediction approach based on neighbourhood analysis. The resulting success...... by the task of grasping unknown objects given visual sensor information. The contributions from this thesis stem from three works that all relate to the task of grasping unknown objects but with particular focus on the visual representation part of the problem. First an investigation of a visual feature space...... a hierarchical representation of visual surface descriptors in SE(3). The mechanism provides a generic way of creating a hierarchical representation of N layers using pairs of descriptors. The created hierarchies were evaluated on the task of grasping unknown objects and the resulting best success-rate was 65...

  5. Novel topological descriptors for analyzing biological networks

    Directory of Open Access Journals (Sweden)

    Varmuza Kurt K

    2010-06-01

    Full Text Available Abstract Background Topological descriptors, other graph measures, and in a broader sense, graph-theoretical methods, have been proven as powerful tools to perform biological network analysis. However, the majority of the developed descriptors and graph-theoretical methods does not have the ability to take vertex- and edge-labels into account, e.g., atom- and bond-types when considering molecular graphs. Indeed, this feature is important to characterize biological networks more meaningfully instead of only considering pure topological information. Results In this paper, we put the emphasis on analyzing a special type of biological networks, namely bio-chemical structures. First, we derive entropic measures to calculate the information content of vertex- and edge-labeled graphs and investigate some useful properties thereof. Second, we apply the mentioned measures combined with other well-known descriptors to supervised machine learning methods for predicting Ames mutagenicity. Moreover, we investigate the influence of our topological descriptors - measures for only unlabeled vs. measures for labeled graphs - on the prediction performance of the underlying graph classification problem. Conclusions Our study demonstrates that the application of entropic measures to molecules representing graphs is useful to characterize such structures meaningfully. For instance, we have found that if one extends the measures for determining the structural information content of unlabeled graphs to labeled graphs, the uniqueness of the resulting indices is higher. Because measures to structurally characterize labeled graphs are clearly underrepresented so far, the further development of such methods might be valuable and fruitful for solving problems within biological network analysis.

  6. RAID: a relation-augmented image descriptor

    KAUST Repository

    Guerrero, Paul

    2016-07-11

    As humans, we regularly interpret scenes based on how objects are related, rather than based on the objects themselves. For example, we see a person riding an object X or a plank bridging two objects. Current methods provide limited support to search for content based on such relations. We present RAID, a relation-augmented image descriptor that supports queries based on inter-region relations. The key idea of our descriptor is to encode region-to-region relations as the spatial distribution of point-to-region relationships between two image regions. RAID allows sketch-based retrieval and requires minimal training data, thus making it suited even for querying uncommon relations. We evaluate the proposed descriptor by querying into large image databases and successfully extract nontrivial images demonstrating complex inter-region relations, which are easily missed or erroneously classified by existing methods. We assess the robustness of RAID on multiple datasets even when the region segmentation is computed automatically or very noisy.

  7. Reactivity of Alkyldibenzothiophenes Using Theoretical Descriptors

    Directory of Open Access Journals (Sweden)

    Jose Luis Rivera

    2014-01-01

    Full Text Available Theoretical calculations of the reactivity of dibenzothiophene and its methyl, dimethyl, and trimethyl derivatives show that local reactivity descriptors reproduce their experimental desulfurization reactivity trend if the first desulfurization step involves directly the sulfur atom, which only occurs if the sulfur atom is blocked at most by one methyl group. In the series of molecules {4,7-dimethyldibenzothiophene, x,4,7-trimethyldibenzothiophene (x=1,2,3}, the most reactive molecule is 2,4,7-trimethyldibenzothiophene, and local descriptors show that the reactivity is linked to the activity of the sulfur atom, which is higher in 2,4,7-trimethyldibenzothiophene due to the position of the third methyl substitute, located in the para position with respect to the carbon bonded to the sulfur atom. The electrostatic potential of 2,4,7-trimethyldibenzothiophene shows one effective adsorption site, while 1,4,7-trimethyldibenzothiophene and 3,4,7-trimethyldibenzothiophene have more sites, contributing to the higher reactivity of 2,4,7-trimethyldibenzothiophene. The index of reactivity of other descriptors was evaluated and the effect of the position of the methyl substituents on adsorption parameters, as the dipole moment and the atomic charges were also studied.

  8. TreeBASIS Feature Descriptor and Its Hardware Implementation

    Directory of Open Access Journals (Sweden)

    Spencer Fowers

    2014-01-01

    Full Text Available This paper presents a novel feature descriptor called TreeBASIS that provides improvements in descriptor size, computation time, matching speed, and accuracy. This new descriptor uses a binary vocabulary tree that is computed using basis dictionary images and a test set of feature region images. To facilitate real-time implementation, a feature region image is binary quantized and the resulting quantized vector is passed into the BASIS vocabulary tree. A Hamming distance is then computed between the feature region image and the effectively descriptive basis dictionary image at a node to determine the branch taken and the path the feature region image takes is saved as a descriptor. The TreeBASIS feature descriptor is an excellent candidate for hardware implementation because of its reduced descriptor size and the fact that descriptors can be created and features matched without the use of floating point operations. The TreeBASIS descriptor is more computationally and space efficient than other descriptors such as BASIS, SIFT, and SURF. Moreover, it can be computed entirely in hardware without the support of a CPU for additional software-based computations. Experimental results and a hardware implementation show that the TreeBASIS descriptor compares well with other descriptors for frame-to-frame homography computation while requiring fewer hardware resources.

  9. The recent progress in proteochemometric modelling: focusing on target descriptors, cross-term descriptors and application scope.

    Science.gov (United States)

    Qiu, Tianyi; Qiu, Jingxuan; Feng, Jun; Wu, Dingfeng; Yang, Yiyan; Tang, Kailin; Cao, Zhiwei; Zhu, Ruixin

    2017-01-01

    As an extension of the conventional quantitative structure activity relationship models, proteochemometric (PCM) modelling is a computational method that can predict the bioactivity relations between multiple ligands and multiple targets. Traditional PCM modelling includes three essential elements: descriptors (including target descriptors, ligand descriptors and cross-term descriptors), bioactivity data and appropriate learning functions that link the descriptors to the bioactivity data. Since its appearance, PCM modelling has developed rapidly over the past decade by taking advantage of the progress of different descriptors and machine learning techniques, along with the increasing amounts of available bioactivity data. Specifically, the new emerging target descriptors and cross-term descriptors not only significantly increased the performance of PCM modelling but also expanded its application scope from traditional protein-ligand interaction to more abundant interactions, including protein-peptide, protein-DNA and even protein-protein interactions. In this review, target descriptors and cross-term descriptors, as well as the corresponding application scope, are intensively summarized. Additionally, we look forward to seeing PCM modelling extend into new application scopes, such as Target-Catalyst-Ligand systems, with the further development of descriptors, machine learning techniques and increasing amounts of available bioactivity data. © The Author 2016. Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  10. INVARIANT DESCRIPTOR LEARNING USING A SIAMESE CONVOLUTIONAL NEURAL NETWORK

    Directory of Open Access Journals (Sweden)

    L. Chen

    2016-06-01

    Full Text Available In this paper we describe learning of a descriptor based on the Siamese Convolutional Neural Network (CNN architecture and evaluate our results on a standard patch comparison dataset. The descriptor learning architecture is composed of an input module, a Siamese CNN descriptor module and a cost computation module that is based on the L2 Norm. The cost function we use pulls the descriptors of matching patches close to each other in feature space while pushing the descriptors for non-matching pairs away from each other. Compared to related work, we optimize the training parameters by combining a moving average strategy for gradients and Nesterov's Accelerated Gradient. Experiments show that our learned descriptor reaches a good performance and achieves state-of-art results in terms of the false positive rate at a 95 % recall rate on standard benchmark datasets.

  11. The Classification of HEp-2 Cell Patterns Using Fractal Descriptor.

    Science.gov (United States)

    Xu, Rudan; Sun, Yuanyuan; Yang, Zhihao; Song, Bo; Hu, Xiaopeng

    2015-07-01

    Indirect immunofluorescence (IIF) with HEp-2 cells is considered as a powerful, sensitive and comprehensive technique for analyzing antinuclear autoantibodies (ANAs). The automatic classification of the HEp-2 cell images from IIF has played an important role in diagnosis. Fractal dimension can be used on the analysis of image representing and also on the property quantification like texture complexity and spatial occupation. In this study, we apply the fractal theory in the application of HEp-2 cell staining pattern classification, utilizing fractal descriptor firstly in the HEp-2 cell pattern classification with the help of morphological descriptor and pixel difference descriptor. The method is applied to the data set of MIVIA and uses the support vector machine (SVM) classifier. Experimental results show that the fractal descriptor combining with morphological descriptor and pixel difference descriptor makes the precisions of six patterns more stable, all above 50%, achieving 67.17% overall accuracy at best with relatively simple feature vectors.

  12. Invariant Descriptor Learning Using a Siamese Convolutional Neural Network

    Science.gov (United States)

    Chen, L.; Rottensteiner, F.; Heipke, C.

    2016-06-01

    In this paper we describe learning of a descriptor based on the Siamese Convolutional Neural Network (CNN) architecture and evaluate our results on a standard patch comparison dataset. The descriptor learning architecture is composed of an input module, a Siamese CNN descriptor module and a cost computation module that is based on the L2 Norm. The cost function we use pulls the descriptors of matching patches close to each other in feature space while pushing the descriptors for non-matching pairs away from each other. Compared to related work, we optimize the training parameters by combining a moving average strategy for gradients and Nesterov's Accelerated Gradient. Experiments show that our learned descriptor reaches a good performance and achieves state-of-art results in terms of the false positive rate at a 95 % recall rate on standard benchmark datasets.

  13. Weighted measurement fusion Kalman estimator for multisensor descriptor system

    Science.gov (United States)

    Dou, Yinfeng; Ran, Chenjian; Gao, Yuan

    2016-08-01

    For the multisensor linear stochastic descriptor system with correlated measurement noises, the fused measurement can be obtained based on the weighted least square (WLS) method, and the reduced-order state components are obtained applying singular value decomposition method. Then, the multisensor descriptor system is transformed to a fused reduced-order non-descriptor system with correlated noise. And the weighted measurement fusion (WMF) Kalman estimator of this reduced-order subsystem is presented. According to the relationship of the presented non-descriptor system and the original descriptor system, the WMF Kalman estimator and its estimation error variance matrix of the original multisensor descriptor system are presented. The presented WMF Kalman estimator has global optimality, and can avoid computing these cross-variances of the local Kalman estimator, compared with the state fusion method. A simulation example about three-sensors stochastic dynamic input and output systems in economy verifies the effectiveness.

  14. Fingerprint identification using SIFT-based minutia descriptors and improved all descriptor-pair matching.

    Science.gov (United States)

    Zhou, Ru; Zhong, Dexing; Han, Jiuqiang

    2013-03-06

    The performance of conventional minutiae-based fingerprint authentication algorithms degrades significantly when dealing with low quality fingerprints with lots of cuts or scratches. A similar degradation of the minutiae-based algorithms is observed when small overlapping areas appear because of the quite narrow width of the sensors. Based on the detection of minutiae, Scale Invariant Feature Transformation (SIFT) descriptors are employed to fulfill verification tasks in the above difficult scenarios. However, the original SIFT algorithm is not suitable for fingerprint because of: (1) the similar patterns of parallel ridges; and (2) high computational resource consumption. To enhance the efficiency and effectiveness of the algorithm for fingerprint verification, we propose a SIFT-based Minutia Descriptor (SMD) to improve the SIFT algorithm through image processing, descriptor extraction and matcher. A two-step fast matcher, named improved All Descriptor-Pair Matching (iADM), is also proposed to implement the 1:N verifications in real-time. Fingerprint Identification using SMD and iADM (FISiA) achieved a significant improvement with respect to accuracy in representative databases compared with the conventional minutiae-based method. The speed of FISiA also can meet real-time requirements.

  15. Fingerprint Identification Using SIFT-Based Minutia Descriptors and Improved All Descriptor-Pair Matching

    Directory of Open Access Journals (Sweden)

    Jiuqiang Han

    2013-03-01

    Full Text Available The performance of conventional minutiae-based fingerprint authentication algorithms degrades significantly when dealing with low quality fingerprints with lots of cuts or scratches. A similar degradation of the minutiae-based algorithms is observed when small overlapping areas appear because of the quite narrow width of the sensors. Based on the detection of minutiae, Scale Invariant Feature Transformation (SIFT descriptors are employed to fulfill verification tasks in the above difficult scenarios. However, the original SIFT algorithm is not suitable for fingerprint because of: (1 the similar patterns of parallel ridges; and (2 high computational resource consumption. To enhance the efficiency and effectiveness of the algorithm for fingerprint verification, we propose a SIFT-based Minutia Descriptor (SMD to improve the SIFT algorithm through image processing, descriptor extraction and matcher. A two-step fast matcher, named improved All Descriptor-Pair Matching (iADM, is also proposed to implement the 1:N verifications in real-time. Fingerprint Identification using SMD and iADM (FISiA achieved a significant improvement with respect to accuracy in representative databases compared with the conventional minutiae-based method. The speed of FISiA also can meet real-time requirements.

  16. Video shot boundary detection using motion activity descriptor

    CERN Document Server

    Amel, Abdelati Malek; Abdellatif, Mtibaa

    2010-01-01

    This paper focus on the study of the motion activity descriptor for shot boundary detection in video sequences. We interest in the validation of this descriptor in the aim of its real time implementation with reasonable high performances in shot boundary detection. The motion activity information is extracted in uncompressed domain based on adaptive rood pattern search (ARPS) algorithm. In this context, the motion activity descriptor was applied for different video sequence.

  17. LOAD: Local Orientation Adaptive Descriptor for Texture and Material Classification

    OpenAIRE

    Qi, Xianbiao; Zhao, Guoying; Shen, Linlin; Li, Qingquan; Pietikainen, Matti

    2015-01-01

    In this paper, we propose a novel local feature, called Local Orientation Adaptive Descriptor (LOAD), to capture regional texture in an image. In LOAD, we proposed to define point description on an Adaptive Coordinate System (ACS), adopt a binary sequence descriptor to capture relationships between one point and its neighbors and use multi-scale strategy to enhance the discriminative power of the descriptor. The proposed LOAD enjoys not only discriminative power to capture the texture informa...

  18. Heliconia phenotypic diversity based on qualitative descriptors.

    Science.gov (United States)

    Guimarães, W N R; Martins, L S S; Castro, C E F; Carvalho Filho, J L S; Loges, V

    2014-04-17

    The aim of this study was to characterize Heliconia genotypes phenotypically using 26 qualitative descriptors. The evaluations were conducted in five flowering stems per clump in three replicates of 22 Heliconia genotypes. Data were subjected to multivariate analysis, the Mahalanobis dissimilarity measure was estimated, and the dendrogram was generated using the nearest neighbor method. From the values generated by the dissimilarity matrix and the clusters formed among the Heliconia genotypes studied, the phenotypic characterizations that best differentiated the genotypes were: pseudostem and wax green tone (light or dark green), leaf-wax petiole, the petiole hair, cleft margin at the base of the petiole, midrib underside shade of green, wax midrib underside, color sheet (light or dark green), unequal lamina base, torn limb, inflorescence-wax, position of inflorescence, bract leaf in apex, twisting of the rachis, and type of bloom. These results will be applied in the preparation of a catalog for Heliconia descriptors, in the selection of different genotypes with most promising characteristics for crosses, and for the characterization of new genotypes to be introduced in germplasm collections.

  19. Object classification and detection with context kernel descriptors

    DEFF Research Database (Denmark)

    Pan, Hong; Olsen, Søren Ingvor; Zhu, Yaping

    2014-01-01

    Context information is important in object representation. By embedding context cue of image attributes into kernel descriptors, we propose a set of novel kernel descriptors called Context Kernel Descriptors (CKD) for object classification and detection. The motivation of CKD is to use spatial...... consistency of image attributes or features defined within a neighboring region to improve the robustness of descriptor matching in kernel space. For feature selection, Kernel Entropy Component Analysis (KECA) is exploited to learn a subset of discriminative CKD. Different from Kernel Principal Component...

  20. A robust HOG-based descriptor for pattern recognition

    Science.gov (United States)

    Diaz-Escobar, Julia; Kober, Vitaly

    2016-09-01

    The Histogram of Oriented Gradients (HOG) is a popular feature descriptor used in computer vision and image processing. The technique counts occurrences of gradient orientation in localized portions of an image. The descriptor is sensible to the presence in images of noise, nonuniform illumination, and low contrast. In this work, we propose a robust HOG-based descriptor using the local energy model and phase congruency approach. Computer simulation results are presented for recognition of objects in images affected by additive noise, nonuniform illumination, and geometric distortions using the proposed and conventional HOG descriptors.

  1. Image matching with an improved descriptor based on SIFT

    Science.gov (United States)

    Hu, Xuemei; Ding, Yan

    2017-01-01

    In this paper, we propose a novel 30-dimension descriptor named SIFTRO(SIFT of Ring Order) to promote the matching speed, which is generated from 3 local ring areas. A new element reordering method is presented to ensure the descriptor's rotation invariance. To obtain the best scale factor for SIFTRO descriptor, the weight hierarchy decision model based on AHP is designed. The experiments show that the SIFTRO descriptor inherits the advantages of the invariance to image scaling, rotation and affine, and it also speeds up greatly in image matching, while the precision is improved compared with that of original SIFT.

  2. Pole assignment in descriptor periodic systems

    Institute of Scientific and Technical Information of China (English)

    FAN; Hung-Yuan; LIN; Wen-Wei; XU; Shufang

    2005-01-01

    In this paper a pole assignment problem is considered for the descriptor linear discrete-time periodic systems, which is using the periodic proportional-derivative feedback to modify a given system such that the closed loop system has a specified selfconjugate set of eigenvalues. It is shown that the complete reachability of an open loop periodic system is equivalent to the possibility of assigning an arbitrary set of the eigenvalues to the system by choosing the suitable periodic proportional-derivative feedback.A computational approach is also proposed to solve the problem, which uses the reliable numerical techniques based on the orthogonal transformations. Numerical examples are presented to illustrate the effectiveness of the proposed approach.

  3. Aggregating local image descriptors into compact codes.

    Science.gov (United States)

    Jégou, Hervé; Perronnin, Florent; Douze, Matthijs; Sánchez, Jorge; Pérez, Patrick; Schmid, Cordelia

    2012-09-01

    This paper addresses the problem of large-scale image search. Three constraints have to be taken into account: search accuracy, efficiency, and memory usage. We first present and evaluate different ways of aggregating local image descriptors into a vector and show that the Fisher kernel achieves better performance than the reference bag-of-visual words approach for any given vector dimension. We then jointly optimize dimensionality reduction and indexing in order to obtain a precise vector comparison as well as a compact representation. The evaluation shows that the image representation can be reduced to a few dozen bytes while preserving high accuracy. Searching a 100 million image data set takes about 250 ms on one processor core.

  4. Szeged Matrix Property Indices as Descriptors to Characterize Fullerenes

    Directory of Open Access Journals (Sweden)

    Jäntschi Lorentz

    2016-12-01

    Full Text Available Fullerenes are class of allotropes of carbon organized as closed cages or tubes of carbon atoms. The fullerenes with small number of atoms were not frequently investigated. This paper presents a detailed treatment of total strain energy as function of structural feature extracted from isomers of C40 fullerene using Szeged Matrix Property Indices (SMPI. The paper has a two-fold structure. First, the total strain energy of C40 fullerene isomers (40 structures was linked with SMPI descriptors under two scenarios, one which incorporate just the SMPI descriptors and the other one which contains also five calculated properties (dipole moment, scf-binding-energy, scf-core-energy, scf-electronic-energy, and heat of formation. Second, the performing models identified on C40 fullerene family or the descriptors of these models were used to predict the total strain energy on C42 fullerene isomers. The obtained results show that the inclusion of properties in the pool of descriptors led to the reduction of accurate linear models. One property, namely scf-binding-energy proved a significant contribution to total strain energy of C40 fullerene isomers. However, the top-three most performing models contain just SMPI descriptors. A model with four descriptors proved most accurate model and show fair abilities in prediction of the same property on C42 fullerene isomers when the approach considered the descriptors identified on C40 as the predicting descriptors for C42 fullerene isomers.

  5. Sparse B-spline polynomial descriptors for human activity recognition

    NARCIS (Netherlands)

    Oikonomopoulos, Antonios; Pantic, Maja; Patras, Ioannis

    2009-01-01

    The extraction and quantization of local image and video descriptors for the subsequent creation of visual codebooks is a technique that has proved very effective for image and video retrieval applications. In this paper we build on this concept and propose a new set of visual descriptors that

  6. Short local descriptors from 2D connected pattern spectra

    NARCIS (Netherlands)

    Bosilj, Petra; Kijak, Ewa; Wilkinson, Michael H. F.; Lefèvre, Sebastien

    2015-01-01

    We propose a local region descriptor based on connected pattern spectra, and combined with normalized central moments. The descriptors are calculated for MSER regions of the image, and their performance compared against SIFT. The MSER regions were chosen because they can be efficiently selected by c

  7. Domain-Size Pooling in Local Descriptors: DSP-SIFT

    OpenAIRE

    Dong, Jingming; Soatto, Stefano

    2014-01-01

    We introduce a simple modification of local image descriptors, such as SIFT, based on pooling gradient orientations across different domain sizes, in addition to spatial locations. The resulting descriptor, which we call DSP-SIFT, outperforms other methods in wide-baseline matching benchmarks, including those based on convolutional neural networks, despite having the same dimension of SIFT and requiring no training.

  8. A Multiphilic Descriptor for Chemical Reactivity and Selectivity

    CERN Document Server

    Padmanabhan, J; Elango, M; Subramanian, V; Krishnamoorthy, B S; Gutierrez-Oliva, S; Toro-Labbe, A; Roy, D R; Chattaraj, P K

    2007-01-01

    In line with the local philicity concept proposed by Chattaraj et al. (Chattaraj, P. K.; Maiti, B.; Sarkar, U. J. Phys. Chem. A. 2003, 107, 4973) and a dual descriptor derived by Toro-Labbe and coworkers (Morell, C.; Grand, A.; Toro-Labbe, A. J. Phys. Chem. A. 2005, 109, 205), we propose a multiphilic descriptor. It is defined as the difference between nucleophilic (Wk+) and electrophilic (Wk-) condensed philicity functions. This descriptor is capable of simultaneously explaining the nucleophilicity and electrophilicity of the given atomic sites in the molecule. Variation of these quantities along the path of a soft reaction is also analyzed. Predictive ability of this descriptor has been successfully tested on the selected systems and reactions. Corresponding force profiles are also analyzed in some representative cases. Also, to study the intra- and intermolecular reactivities another related descriptor namely, the nucleophilicity excess (DelW-+) for a nucleophile, over the electrophilicity in it has been d...

  9. Land Cover

    Data.gov (United States)

    Kansas Data Access and Support Center — The Land Cover database depicts 10 general land cover classes for the State of Kansas. The database was compiled from a digital classification of Landsat Thematic...

  10. DEVELOPING CEFR ILLUSTRATIVE DESCRIPTORS OF ASPECTS OF MEDIATION

    Directory of Open Access Journals (Sweden)

    Brian North

    2016-04-01

    Full Text Available This article reports on a project commissioned and coordinated by the Council of Europe to develop descriptors for the category ‘Mediation’ in the Common European Framework of Reference for Languages. Mediation is the fourth communicative language activity presented in CEFR Chapter 4, complementing reception, interaction and production. Descriptors for mediation had not been developed in the 1993–6 Swiss National Research Project that produced the original set of illustrative descriptors for the CEFR. The work took place in the context of a wider 2013–6 project to provide an extended set of CEFR illustrative descriptors. The article describes the way in which the approach taken to mediation in the project is broader than the one taken in the presentation of mediation in the CEFR text in 2001. In addition to information transfer (conveying received information the new scheme also embraces the construction of meaning and relational mediation: the process of establishing and managing interpersonal relationships in order to create a positive, collaborative environment. Descriptors were also developed for other, related, areas. The article briefly summarises the three phases of validation to which the draft descriptors were subjected before being calibrated to the mathematic scale underlying the CEFR’s levels and descriptors.

  11. JET ENGINE INLET DISTORTION SCREEN AND DESCRIPTOR EVALUATION

    Directory of Open Access Journals (Sweden)

    Jiří Pečinka

    2017-02-01

    Full Text Available Total pressure distortion is one of the three basic flow distortions (total pressure, total temperature and swirl distortion that might appear at the inlet of a gas turbine engine (GTE during operation. Different numerical parameters are used for assessing the total pressure distortion intensity and extent. These summary descriptors are based on the distribution of total pressure in the aerodynamic interface plane. There are two descriptors largely spread around the world, however, three or four others are still in use and can be found in current references. The staff at the University of Defence decided to compare the most common descriptors using basic flow distortion patterns in order to select the most appropriate descriptor for future department research. The most common descriptors were identified based on their prevalence in widely accessible publications. The construction and use of these descriptors are reviewed in the paper. Subsequently, they are applied to radial, angular, and combined distortion patterns of different intensities and with varied mass flow rates. The tests were performed on a specially designed test bench using an electrically driven standalone industrial centrifugal compressor, sucking air through the inlet of a TJ100 small turbojet engine. Distortion screens were placed into the inlet channel to create the desired total pressure distortions. Of the three basic distortions, only the total pressure distortion descriptors were evaluated. However, both total and static pressures were collected using a multi probe rotational measurement system.

  12. Binary descriptor-based dense line-scan stereo matching

    Science.gov (United States)

    Valentín, Kristián; Huber-Mörk, Reinhold; Štolc, Svorad

    2017-01-01

    We present a line-scan stereo system and descriptor-based dense stereo matching for high-performance vision applications. The stochastic binary local descriptor (STABLE) descriptor is a local binary descriptor that builds upon the principles of compressed sensing theory. The most important properties of STABLE are the independence of the descriptor length from the matching window size and the possibility that more than one pair of pixels contributes to a single-descriptor bit. Individual descriptor bits are computed by comparing image intensities over pairs of balanced random subsets of pixels chosen from the whole described area. On a synthetic as well as real-world examples, we demonstrate that STABLE provides competitive or superior performance than other state-of-the-art local binary descriptors in the task of dense stereo matching. The real-world example is derived from line-scan binocular stereo imaging, i.e., two line-scan cameras are observing the same object line and 2-D images are generated due to relative motion. We show that STABLE performs significantly better than the census transform and local binary patterns (LBP) in all considered geometric and radiometric distortion categories to be expected in practical applications of stereo vision. Moreover, we show as well that STABLE provides comparable or better matching quality than the binary robust-independent elementary features descriptor. The low computational complexity and flexible memory footprint make STABLE well suited for most hardware architectures. We present quantitative results based on the Middlebury stereo dataset as well as illustrative results for road surface reconstruction.

  13. Descriptors for Pentane-2,4-dione and Its Derivatives.

    Science.gov (United States)

    Abraham, Michael H; Acree, William E

    2017-01-01

    We have used equations for partition coefficients of compounds from water and the gas phase to various solvents to obtain descriptors for pentane-2,4-dione and 21 of its derivatives. These descriptors can then be used to estimate further partition coefficients into a wide variety of solvents. The descriptors also yield information about the properties of pentane-2,4-dione and its derivatives. Pentane-2,4-dione and its alkyl derivatives are quite polar, with substantial hydrogen bond basicity but with no hydrogen bond acidity. In contrast 1,1,1-trifluoropentane-2,4-dione and hexafluoropentan-2,4-dione have significant hydrogen bond acidities.

  14. Gabor Weber Local Descriptor for Bovine Iris Recognition

    Directory of Open Access Journals (Sweden)

    Shengnan Sun

    2013-01-01

    Full Text Available Iris recognition is a robust biometric technology. This paper proposes a novel local descriptor for bovine iris recognition, named Gabor Weber local descriptor (GWLD. We first compute the Gabor magnitude maps for the input bovine iris image, and then calculate the differential excitation and orientation for each pixel over each Gabor magnitude map. After that, we use these differential excitations and orientations to construct the GWLD histogram representation. Finally, histogram intersection is adopted to measure the similarity between different GWLD histograms. The experimental results on the SEU bovine iris database verify the representation power of our proposed local descriptor.

  15. Dissipativity Analysis of Descriptor Systems Using Image Space Characterization

    Directory of Open Access Journals (Sweden)

    Liang Qiao

    2014-01-01

    Full Text Available In this paper, we analyze the dissipativity for descriptor systems with impulsive behavior based on image space analysis. First, a new image space is used to characterize state responses for descriptor systems. Based on such characterization and an integral property of delta function, a new necessary and sufficient condition for the dissipativity of descriptor systems is derived using the linear matrix inequality (LMI approach. Also, some of the earlier related results on dissipativity for linear systems are investigated in the framework proposed in this paper. Finally, two examples are given to show the validity of the derived results.

  16. Fractal and Euclidean descriptors of platelet shape.

    Science.gov (United States)

    Kraus, Max-Joseph; Neeb, Heiko; Strasser, Erwin F

    2014-01-01

    Platelet shape change is a dynamic membrane surface process that exhibits remarkable morphological heterogeneity. Once the outline of an irregular shape is identified and segmented from a digital image, several mathematical descriptors can be applied to numerical characterize the irregularity of the shapes surface. 13072 platelet outlines (PLO) were segmented automatically from 1928 microscopic images using a newly developed algorithm for the software product Matlab R2012b. The fractal dimension (FD), circularity, eccentricity, area and perimeter of each PLO were determined. 972 PLO were randomly assigned for computer-assisted manual measurement of platelet diameter as well as number, width and length of filopodia per platelet. FD can be used as a surrogate parameter for determining the roughness of the PLO and circularity can be used as a surrogate to estimate the number and length of filopodia. The relationship between FD and perimeter of the PLO reveals the existence of distinct groups of platelets with significant structural differences which may be caused by platelet activation. This new method allows for the standardized continuous numerical classification of platelet shape and its dynamic change, which is useful for the analysis of altered platelet activity (e.g. inflammatory diseases, contact activation, drug testing).

  17. Gait Recognition based on Dynamic Texture descriptors

    Directory of Open Access Journals (Sweden)

    B. Abdolahi

    2013-09-01

    Full Text Available The human movement analysis is an attractive topic in biometric research. Recent studies indicate that people have considerable ability to recognize others by their natural walking. Therefore, gait recognition has obtained great interest in biometric systems. The common biometrics is usually time-consuming, limited and collaborative. These drawbacks pose major challenges to the recognition process. Gait analysis is inconspicuous, needs no contact, is difficult to hide and can be evaluated at distance. This paper presents a bag of word method for gait recognition based on dynamic textures. Dynamic textures combine appearance and motion information. Since human walking has statistical variations in both spatial and temporal space, it can be described with dynamic texture features. To obtain these features, we extract spatiotemporal interest points and describe them by a dynamic texture descriptor. Afterwards, the hierarchical K-means as a clustering algorithm is applied to obtain the visual dictionary of video-words. As a result, human walking is represented as a histogram of video-words occurrences. The performance of our method is evaluated on two dataset: the KTH and IXMAS multiview datasets.

  18. Both mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2 and phosphatidylinositide-3-OH kinase (PI3K)/Akt pathways regulate activation of E-twenty-six (ETS)-like transcription factor 1 (Elk-1) in U138 glioblastoma cells.

    Science.gov (United States)

    Mut, Melike; Lule, Sevda; Demir, Ozlem; Kurnaz, Isil Aksan; Vural, Imran

    2012-02-01

    Epidermal growth factor (EGF) and its receptor (EGFR) have been shown to play a significant role in the pathogenesis of glioblastoma. In our study, the EGFR was stimulated with EGF in human U138 glioblastoma cells. We show that the activated mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2 pathway phosphorylated the E twenty-six (ETS)-like transcription factor 1 (Elk-1) mainly at serine 383 residue. Mitogen-activated protein kinase kinase (MEK) 1/2 inhibitor, UO126 and ERK inhibitor II, FR180204 blocked the Elk-1 phosphorylation and activation. The phosphatidylinositide-3-OH kinase (PI3K)/Akt pathway was also involved in the Elk-1 activation. Activation of the Elk-1 led to an increased survival and a proliferative response with the EGF stimulation in the U138 glioblastoma cells. Knocking-down the Elk-1 using an RNA interference technique caused a decrease in survival of the unstimulated U138 glioblastoma cells and also decreased the proliferative response to the EGF stimulation. The Elk-1 transcription factor was important for the survival and proliferation of U138 glioblastoma cells upon the stimulation of EGFR with EGF. The MAPK/ERK1/2 and PI3K/Akt pathways regulated this response via activation of the Elk-1 transcription factor. The Elk-1 may be one of the convergence points for pathways located downstream of EGFR in glioblastoma cells. Utilization of the Elk-1 as a therapeutic target may lead to a novel strategy in treatment of glioblastoma.

  19. Impact sound insulation descriptors in the Nordic building regulations – Overview special rules and benefits of changing descriptors

    DEFF Research Database (Denmark)

    Hagberg, Klas; Rasmussen, Birgit

    2010-01-01

    of similarities. However, the descriptors and other rules differ more than what is obvious at the first glance. The present use of different descriptors and additional rules is partly a heritage from the past and partly caused by later national revisions without cooperation with the other Nordic countries...... insulation requirements and is related to an equivalent paper about airborne sound insulation requirements. The papers also describe the major benefits of reducing the number of special rules and of changing descriptors to those which best support protection of the residents and development of the building...... industry, both aspects in consideration of the European perspective and cooperation in COST Action TU0901....

  20. Airborne sound insulation descriptors in the Nordic building regulations - Overview special rules and benefits of changing descriptors

    DEFF Research Database (Denmark)

    Helimäki, Heikki; Rasmussen, Birgit

    2010-01-01

    of similarities. However, the descriptors and other rules differ more than what is obvious at the first glance. The present use of different descriptors and additional rules is partly a heritage from the past and partly caused by later national revisions without cooperation with the other Nordic countries...... insulation requirements and is related to an equivalent paper about impact sound insulation requirements. The papers also describe the major benefits of reducing the number of special rules and of changing descriptors to those which best support protection of the residents and development of the building...... industry, both aspects in consideration of the European perspective and cooperation in COST Action TU0901....

  1. Urology Tag Ontology Project: Standardizing Social Media Communication Descriptors.

    Science.gov (United States)

    Kutikov, Alexander; Woo, Henry H; Catto, James W

    2016-02-01

    Standardizing social media hashtag descriptors is likely to facilitate communication and promote collaboration in both health care provider and patient communities. Copyright © 2015 European Association of Urology. Published by Elsevier B.V. All rights reserved.

  2. Tracking image features with PCA-SURF descriptors

    CSIR Research Space (South Africa)

    Pancham, A

    2015-05-01

    Full Text Available The tracking of moving points in image sequences requires unique features that can be easily distinguished. However, traditional feature descriptors are of high dimension, leading to larger storage requirement and slower computation. In this paper...

  3. Extension of Kalman-Yakubovich-Popov lemma to descriptor systems

    NARCIS (Netherlands)

    Camlibel, M.K.; Frasca, R.

    2007-01-01

    This paper studies concepts of passivity and positive realness for regular descriptor systems. A complete analogue of the well-known Kalman-Yakubovich-Popov lemma is presented. Some of the earlier related results are recovered from the provided results.

  4. Learning to assign binary weights to binary descriptor

    Science.gov (United States)

    Huang, Zhoudi; Wei, Zhenzhong; Zhang, Guangjun

    2016-10-01

    Constructing robust binary local feature descriptors are receiving increasing interest due to their binary nature, which can enable fast processing while requiring significantly less memory than their floating-point competitors. To bridge the performance gap between the binary and floating-point descriptors without increasing the computational cost of computing and matching, optimal binary weights are learning to assign to binary descriptor for considering each bit might contribute differently to the distinctiveness and robustness. Technically, a large-scale regularized optimization method is applied to learn float weights for each bit of the binary descriptor. Furthermore, binary approximation for the float weights is performed by utilizing an efficient alternatively greedy strategy, which can significantly improve the discriminative power while preserve fast matching advantage. Extensive experimental results on two challenging datasets (Brown dataset and Oxford dataset) demonstrate the effectiveness and efficiency of the proposed method.

  5. Characterization of recommended banana cultivars using morphological and molecular descriptors

    Directory of Open Access Journals (Sweden)

    Onildo Nunes de Jesus

    2009-01-01

    Full Text Available New banana varieties with superior agronomical characteristics have been developed through introductionand/or genetic breeding. In order to guarantee its marketing and intellectual property, these new varieties need to becharacterized by efficient inheritable qualitative morphological and molecular descriptors. The aim of the research was tocharacterize recommended banana varieties using qualitative morphological and molecular descriptors. Twelve genotypeswere analyzed using 61 morphological descriptors where 17 were related to the plant, 24 to the bunch and 20 regarding theflower. Eighty-one molecular markers; 47 RAPD primers and 34 SSR primers were used. The morphological and moleculardescriptors were efficient in the characterization and identification of specific characteristics for most of the varieties evaluated.Plant and inflorescence descriptors presented the greatest variability of characteristics that can facilitate its use for cultivarprotection and registration

  6. Shape descriptors for mode-shape recognition and model updating

    Science.gov (United States)

    Wang, W.; Mottershead, J. E.; Mares, C.

    2009-08-01

    The most widely used method for comparing mode shapes from finite elements and experimental measurements is the Modal Assurance Criterion (MAC), which returns a single numerical value and carries no explicit information on shape features. New techniques, based on image processing (IP) and pattern recognition (PR) are described in this paper. The Zernike moment descriptor (ZMD), Fourier descriptor (FD), and wavelet descriptor (WD), presented in this article, are the most popular shape descriptors having properties that include efficiency of expression, robustness to noise, invariance to geometric transformation and rotation, separation of local and global shape features and computational efficiency. The comparison of mode shapes is readily achieved by assembling the shape features of each mode shape into multi-dimensional shape feature vectors (SFVs) and determining the distances separating them.

  7. Verbal descriptors influence hypothalamic response to low-calorie drinks

    Science.gov (United States)

    Veldhuizen, Maria G.; Nachtigal, Danielle J.; Flammer, Linda J.; de Araujo, Ivan E.; Small, Dana M.

    2013-01-01

    Messages describing foods constitute a pervasive form of reward cueing. Different descriptions may produce particular appeal depending upon the individual. To examine the extent to which verbal descriptors and individual differences interact to influence food preferences, we used functional magnetic resonance imaging to measure brain responses to the same low-calorie drinks preceded by the spoken verbal descriptor “treat” or “healthy” in 27 subjects varying in BMI, eating style and reward sensitivity. Subjects also sampled a prototypical milkshake treat. Despite the fact that the verbal descriptor had no influence on pleasantness ratings, preferential responses to the low-calorie drinks labeled “treat” vs. “healthy” were observed in the midbrain and hypothalamus. These same regions were also preferentially responsive to the prototypical treat. These results reveal a previously undocumented influence of verbal descriptors on brain circuits regulating energy homeostasis. PMID:24049739

  8. Recognizing shipbuilding parts using artificial neural networks and Fourier descriptors

    OpenAIRE

    Sanders, David

    2009-01-01

    A pattern recognition system is described for recognizing shipbuilding parts using artificial neural networks and Fourier descriptors. The system uses shape contour information that is invariant of size, translation, and rotation. Fourier descriptors provide information, and the neural networks make decisions about the shapes. A brief review of the current state of the art is included, and results from testing show that the system distinguished between various shapes and proved to be a valid ...

  9. Robustness analysis for a class of nonlinear descriptor systems

    Institute of Scientific and Technical Information of China (English)

    吴敏; 张凌波; 何勇

    2004-01-01

    The robustness analysis problem of a class of nonlinear descriptor systems is studied. Nonlinear matrix inequality which has the good computation property of convex feasibility is employed to derive some sufficient conditions to guarantee that the nonlinear descriptor systems have robust disturbance attenuation performance, which avoids the computational difficulties in conversing nonlinear matrix and Hamilton-Jacobi inequality. The computation property of convex feasibility of nonlinear matrix inequality makes it possible to apply the results of nonlinear robust control to practice.

  10. Generalized regularity and regularizability of rectangular descriptor systems

    Institute of Scientific and Technical Information of China (English)

    Guangren DUAN; Yan CHEN

    2007-01-01

    The notion of generalized regularity is proposed for rectangular descriptor systems. Generalized regularizability of a rectangular descriptor system via different feedback forms is considered. Necessary and sufficient conditions for generalized regularizability are obtained, which are only dependent upon the open-loop coefficient matrices. It is also shown that under these necessary and sufficient conditions, all the generalized regularizing feedback controllers form a Zarisky open set. A numerical example demonstrates the proposed results.

  11. Finding the Best Feature Detector-Descriptor Combination

    DEFF Research Database (Denmark)

    Dahl, Anders Lindbjerg; Aanæs, Henrik; Pedersen, Kim Steenstrup

    2011-01-01

    matching is an interplay of both detector and descriptor methodology. Our main contribution is to evaluate the performance of some of the most popular descriptor and detector combinations on the DTU Robot dataset, which is a very large dataset with massive amounts of systematic data aimed at two view...... collaborating that using affine invariant feature detectors carries a statistical significant advantage on general scene types....

  12. Structure/response correlations and similarity/diversity analysis by GETAWAY descriptors. 2. Application of the novel 3D molecular descriptors to QSAR/QSPR studies.

    Science.gov (United States)

    Consonni, Viviana; Todeschini, Roberto; Pavan, Manuela; Gramatica, Paola

    2002-01-01

    In a previous paper the theory of the new molecular descriptors called GETAWAY (GEometry, Topology, and Atom-Weights AssemblY) was explained. These descriptors have been proposed with the aim of matching 3D-molecular geometry, atom relatedness, and chemical information. In this paper prediction ability in structure-property correlations of GETAWAY descriptors has been tested extensively by analyzing the regressions of these descriptors for selected properties of some reference compound classes. Moreover, the general performance of the new descriptors in QSAR/QSPR has been evaluated with respect to other well-known sets of molecular descriptors.

  13. A minimal descriptor of an ancestral recombinations graph

    Directory of Open Access Journals (Sweden)

    Palamara Pier

    2011-02-01

    Full Text Available Abstract Background Ancestral Recombinations Graph (ARG is a phylogenetic structure that encodes both duplication events, such as mutations, as well as genetic exchange events, such as recombinations: this captures the (genetic dynamics of a population evolving over generations. Results In this paper, we identify structure-preserving and samples-preserving core of an ARG G and call it the minimal descriptor ARG of G. Its structure-preserving characteristic ensures that all the branch lengths of the marginal trees of the minimal descriptor ARG are identical to that of G and the samples-preserving property asserts that the patterns of genetic variation in the samples of the minimal descriptor ARG are exactly the same as that of G. We also prove that even an unbounded G has a finite minimal descriptor, that continues to preserve certain (graph-theoretic properties of G and for an appropriate class of ARGs, our estimate (Eqn 8 as well as empirical observation is that the expected reduction in the number of vertices is exponential. Conclusions Based on the definition of this lossless and bounded structure, we derive local properties of the vertices of a minimal descriptor ARG, which lend itself very naturally to the design of efficient sampling algorithms. We further show that a class of minimal descriptors, that of binary ARGs, models the standard coalescent exactly (Thm 6.

  14. Proposal for qualitative and quantitative descriptors to characterise bamboo germplasm

    Directory of Open Access Journals (Sweden)

    Andressa Leal Generoso

    Full Text Available ABSTRACT Bamboo is a genetic resource with evident potential for use from construction until the recovery of degraded areas. Although, characterization and evaluation studies involving bamboo species are scarce and it is difficult to define a list of specific descriptors to better meet the different genres and or bamboo species. Thus, the objective of this work were propose and test the effectiveness of qualitative and quantitative descriptors for phenotypic characterization and the study of genetic diversity among six species of bamboo introduced in Brazil. Fifteen qualitative and nine quantitative descriptors were proposed and tested in clones with one year of planting. Individuals belonging to six species of bamboo (Bambusa vulgaris, Bambusa vulgaris var. vittata, Drepanostachyum falcatum, Dendrocalamus latiforus, Phyllostachys aurea var. albovariegada and Phyllostachys edulis were characterized on the basis of vegetative descriptors, pseudopetiole, sheath, ligule, gems and culm. The genetic divergence between the clones was estimated by the methods of grouping of Tocher and UPGMA with use of average Euclidean distance and the principal component in two-dimensional plane. Qualitative and quantitative descriptors proposed were efficient to differentiate the six species studied and quantify genetic diversity. The quantitative descriptor of sheath length was the largest contributor to differentiate the species studied.

  15. Benthic Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic cover (habitat) maps are derived from aerial imagery, underwater photos, acoustic surveys, and data gathered from sediment samples. Shallow to moderate-depth...

  16. ANN expert system screening for illicit amphetamines using molecular descriptors

    Science.gov (United States)

    Gosav, S.; Praisler, M.; Dorohoi, D. O.

    2007-05-01

    The goal of this study was to develop and an artificial neural network (ANN) based on computed descriptors, which would be able to classify the molecular structures of potential illicit amphetamines and to derive their biological activity according to the similarity of their molecular structure with amphetamines of known toxicity. The system is necessary for testing new molecular structures for epidemiological, clinical, and forensic purposes. It was built using a database formed by 146 compounds representing drugs of abuse (mainly central stimulants, hallucinogens, sympathomimetic amines, narcotics and other potent analgesics), precursors, or derivatized counterparts. Their molecular structures were characterized by computing three types of descriptors: 38 constitutional descriptors (CDs), 69 topological descriptors (TDs) and 160 3D-MoRSE descriptors (3DDs). An ANN system was built for each category of variables. All three networks (CD-NN, TD-NN and 3DD-NN) were trained to distinguish between stimulant amphetamines, hallucinogenic amphetamines, and nonamphetamines. A selection of variables was performed when necessary. The efficiency with which each network identifies the class identity of an unknown sample was evaluated by calculating several figures of merit. The results of the comparative analysis are presented.

  17. USB: ultrashort binary descriptor for fast visual matching and retrieval.

    Science.gov (United States)

    Zhang, Shiliang; Tian, Qi; Huang, Qingming; Gao, Wen; Rui, Yong

    2014-08-01

    Currently, many local descriptors have been proposed to tackle a basic issue in computer vision: duplicate visual content matching. These descriptors either are represented as high-dimensional vectors relatively expensive to extract and compare or are binary codes limited in robustness. Bag-of-visual words (BoWs) model compresses local features into a compact representation that allows for fast matching and scalable indexing. However, the codebook training, high-dimensional feature extraction, and quantization significantly degrade the flexibility and efficiency of BoWs model. In this paper, we study an alternative to current local descriptors and BoWs model by extracting the ultrashort binary descriptor (USB) and a compact auxiliary spatial feature from each keypoint detected in images. A typical USB is a 24-bit binary descriptor, hence it directly quantizes visual clues of image keypoints to about 16 million unique IDs. USB allows fast image matching and indexing and avoids the expensive codebook training and feature quantization in BoWs model. The spatial feature complementarily captures the spatial configuration in neighbor region of each keypoint, hence is used to filter mismatched USBs in a cascade verification. In image matching task, USB shows promising accuracy and nearly one-order faster speed than SIFT. We also test USB in retrieval tasks on UKbench, Oxford5K, and 1.2 million distractor images. Comparisons with recent retrieval methods manifest the competitive accuracy, memory consumption, and significantly better efficiency of our approach.

  18. Gun bore flaw image matching based on improved SIFT descriptor

    Science.gov (United States)

    Zeng, Luan; Xiong, Wei; Zhai, You

    2013-01-01

    In order to increase the operation speed and matching ability of SIFT algorithm, the SIFT descriptor and matching strategy are improved. First, a method of constructing feature descriptor based on sector area is proposed. By computing the gradients histogram of location bins which are parted into 6 sector areas, a descriptor with 48 dimensions is constituted. It can reduce the dimension of feature vector and decrease the complexity of structuring descriptor. Second, it introduce a strategy that partitions the circular region into 6 identical sector areas starting from the dominate orientation. Consequently, the computational complexity is reduced due to cancellation of rotation operation for the area. The experimental results indicate that comparing with the OpenCV SIFT arithmetic, the average matching speed of the new method increase by about 55.86%. The matching veracity can be increased even under some variation of view point, illumination, rotation, scale and out of focus. The new method got satisfied results in gun bore flaw image matching. Keywords: Metrology, Flaw image matching, Gun bore, Feature descriptor

  19. Descriptor and Folksonomy Concurrence in Education Related Scholarly Research

    Directory of Open Access Journals (Sweden)

    Robert Bruce

    2008-09-01

    Full Text Available Folksonomies are a decentralized yet collaborative form of classification based on user-defined keywords (also known as tags. Although this uncontrolled method of classification lacks rules for term standardization and usage, it has potential for organizational patterns and an emerging vocabulary (terminology. The objective of this research is to analyze the descriptors and tags from journal articles indexed in the Education Resources Information Center (ERIC and the folksonomy-based website CiteULike to determine overlap between the controlled and uncontrolled vocabularies. Metadata from 2,786 journal articles indexed in ERIC and CiteULike was collected using Perl and MySQL. The total metadata was comprised of 2,899 unique ERIC descriptors, 3,176 unique CiteULike tags, and 1,083 unique CiteULike users. An analysis of this metadata revealed that 240 of the CiteULike tags matched ERIC descriptors. The low number of tag-descriptor matches in this research indicates that CiteULike users do not use the same terminology as subject specialists who maintain descriptors in the ERIC thesaurus.

  20. A fast contour descriptor algorithm for supernova imageclassification

    Energy Technology Data Exchange (ETDEWEB)

    Aragon, Cecilia R.; Aragon, David Bradburn

    2006-07-16

    We describe a fast contour descriptor algorithm and its application to a distributed supernova detection system (the Nearby Supernova Factory) that processes 600,000 candidate objects in 80 GB of image data per night. Our shape-detection algorithm reduced the number of false positives generated by the supernova search pipeline by 41% while producing no measurable impact on running time. Fourier descriptors are an established method of numerically describing the shapes of object contours, but transform-based techniques are ordinarily avoided in this type of application due to their computational cost. We devised a fast contour descriptor implementation for supernova candidates that meets the tight processing budget of the application. Using the lowest-order descriptors (F{sub 1} and F{sub -1}) and the total variance in the contour, we obtain one feature representing the eccentricity of the object and another denoting its irregularity. Because the number of Fourier terms to be calculated is fixed and small, the algorithm runs in linear time, rather than the O(n log n) time of an FFT. Constraints on object size allow further optimizations so that the total cost of producing the required contour descriptors is about 4n addition/subtraction operations, where n is the length of the contour.

  1. A Novel Local Structure Descriptor for Color Image Retrieval

    Directory of Open Access Journals (Sweden)

    Zhiyong Zeng

    2016-02-01

    Full Text Available A novel local structure descriptor (LSD for color image retrieval is proposed in this paper. Local structures are defined based on a similarity of edge orientation, and LSD is constructed using the underlying colors in local structures with similar edge direction. LSD can effectively combine color, texture and shape as a whole for image retrieval. LSH integrates the advantages of both statistical and structural texture description methods, and it possesses high indexing capability and low dimensionality. In addition, the proposed feature extraction algorithm does not need to train on a large scale training datasets, and it can extract local structure histogram based on LSD. The experimental results on the Corel image databases show that the descriptor has a better image retrieval performance than other descriptors.

  2. On the Alignment of Shapes Represented by Fourier Descriptors

    DEFF Research Database (Denmark)

    Sjöstrand, Karl; Ericsson, Anders; Larsen, Rasmus

    2006-01-01

    The representation of shapes by Fourier descriptors is a time-honored technique that has received relatively little attention lately. Nevertheless, it has many benefits and is applicable for describing a range of medical structures in two dimensions. Delineations in medical applications often...... consist of continuous outlines of structures, where no information of correspondence between samples exist. In this article, we discuss an alignment method that works directly with the functional representation of Fourier descriptors, and that is optimal in a least-squares sense. With corresponding...... represented by common landmarks can be constructed in an automatic fashion. If the aligned Fourier descriptors are inverse transformed from the frequency domain to the spatial domain, a set of roughly aligned landmarks are obtained. The positions of these are then adjusted along the contour of the objects...

  3. Effect of coordinate rotation on 3D molecular descriptors computed by DragonX

    CERN Document Server

    Hechinger, Manuel

    2012-01-01

    Quantitative structure-property relations (QSPR) employing descriptors derived from the 3D molecular structure are frequently applied for property prediction in various fields of research. In particular, DragonX is one of the most widely used software packages for descriptor calculation. The reliability of 3D molecular descriptors computed by DragonX has lately been investigated, thereby focusing on the effect of computational methods used for molecular structure optimization on the accuracy of the resulting molecular descriptors. The present contribution extends the analysis to a more intrinsic problem of DragonX descriptor evaluation resulting from the sensitivity of the computed 3D descriptors on the coordinate system used for molecule description. Evaluating several 3D descriptors for converged molecular structures rotated around all 3 spatial axes (affine coordinate transformations) yields systematically varying descriptor values. Since this unphysical behavior severely affects the descriptor reliability...

  4. Accumulation of different visual feature descriptors in a coherent framework

    DEFF Research Database (Denmark)

    Jessen, Jeppe Barsøe; Pilz, Florian; Kraft, Dirk;

    2011-01-01

    We present a temporal accumulation scheme which disambiguates different kinds of visual 3D descriptors within one coherent framework. The accumulation consists of a twofold process: First, by means of a Bayesian filtering outliers become eliminated and second, the precision of the extracted...... information becomes enhanced by means of an unscented Kalman filtering process. It is a particular property of our algorithm to be able to deal with different kinds of visual descriptors by the very same mechanism. We show quantitative and qualitative results....

  5. Fourth meeting entitled “Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data”

    CERN Document Server

    Vilanova, Anna; Burgeth, Bernhard; Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data

    2014-01-01

    Arising from the fourth Dagstuhl conference entitled Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data (2011), this book offers a broad and vivid view of current work in this emerging field. Topics covered range from applications of the analysis of tensor fields to research on their mathematical and analytical properties. Part I, Tensor Data Visualization, surveys techniques for visualization of tensors and tensor fields in engineering, discusses the current state of the art and challenges, and examines tensor invariants and glyph design, including an overview of common glyphs. The second Part, Representation and Processing of Higher-order Descriptors, describes a matrix representation of local phase, outlines mathematical morphological operations techniques, extended for use in vector images, and generalizes erosion to the space of diffusion weighted MRI. Part III, Higher Order Tensors and Riemannian-Finsler Geometry, offers powerful mathematical language to model and...

  6. Impulse Controllability : From Descriptor Systems to Higher Order DAEs

    NARCIS (Netherlands)

    Kalpana Kalaimani, Rachel; Praagman, Cornelis; Belur, Madhu N.

    2016-01-01

    Impulsive solutions in LTI dynamical systems have received ample attention, but primarily for descriptor systems, i.e., first order Differential Algebraic Equations (DAEs). This paper focuses on the impulsive behavior of higher order dynamical systems and analyzes the causes of impulses in the conte

  7. Aquaculture Thesaurus: Descriptors Used in the National Aquaculture Information System.

    Science.gov (United States)

    Lanier, James A.; And Others

    This document provides a listing of descriptors used in the National Aquaculture Information System (NAIS), a computer information storage and retrieval system on marine, brackish, and freshwater organisms. Included are an explanation of how to use the document, subject index terms, and a brief bibliography of the literature used in developing the…

  8. Unevenness Point Descriptor for Terrain Analysis in Mobile Robot Applications

    Directory of Open Access Journals (Sweden)

    Mauro Bellone

    2013-07-01

    The proposed algorithm is based on the analysis of the normal vector of a surface obtained through Principal Component Analysis and it leads to the definition of a novel, so defined, Unevenness Point Descriptor. Experimental results, obtained with vehicles operating in indoor and outdoor environments, are presented to validate this approach.

  9. Survey of descriptors on cigarette packs: still misleading consumers?

    Science.gov (United States)

    Peace, Jo; Wilson, Nick; Hoek, Janet; Edwards, Richard; Thomson, George

    2009-09-25

    In September 2008, the New Zealand (NZ) Commerce Commission issued a warning to the major tobacco companies to remove "light" and "mild" descriptors from cigarette packaging. Despite published evidence that suggested tobacco companies had started colour-coding their packs in anticipation of the Commission's decision, the investigation did not consider more general misleading packaging. This study explored changes in tobacco packaging that had been introduced to the New Zealand market, by surveying descriptors used on cigarette packs after the Commerce Commission's warning. A convenience sample of discarded cigarette packs were collected in four cities and six towns/rural areas between November 2008 and January 2009. The majority of packs (93%) were collected in the capital city (Wellington). Information on the descriptors and pack colours was analysed. Four percent of the 1208 packs collected still included the terms "light" and "mild". Almost half the packs (42%) used a colour word (e.g. red, blue, gold) as a descriptor to indicate mildness or strength. A further 18% used other words that suggested mildness/strength (e.g. "subtle", "mellow"). A quarter of packs used a descriptor that did not connote either mildness or strength; however, the majority of these packs still appeared to be colour-coded. Although the words "light" and "mild" have been largely removed from tobacco packaging in the New Zealand market, these words have been replaced with associated colours or other words that may continue to communicate "reduced harm" messages to consumers. Further research to test how smokers interpret the new words and colours, and how these influence their behaviour, is desirable. However, government-mandated generic (plain) packaging would remove the opportunity to communicate misleading claims and so would afford the highest level of consumer protection.

  10. Clinical descriptors for the recognition of central sensitization pain in patients with knee osteoarthritis

    DEFF Research Database (Denmark)

    Lluch, Enrique; Nijs, Jo; Courtney, Carol A

    2017-01-01

    hyperalgesia, hypoesthesia and reduced vibration sense. CONCLUSIONS: This article describes a set of clinically relevant descriptors that might indicate the presence of central sensitization in patients with knee osteoarthritis in clinical practice. Although based on research data, the descriptors proposed...

  11. Sound insulation between dwellings - Descriptors applied in building regulations in Europe

    DEFF Research Database (Denmark)

    Rasmussen, Birgit; Rindel, Jens Holger

    2010-01-01

    was carried out of legal sound insulation requirements in 24 countries in Europe. The comparison of requirements for sound insulation between dwellings revealed significant differences in descriptors as well as levels. This paper focuses on descriptors and summarizes the history of descriptors, the problems...

  12. Evaluation of vegetation post-fire resilience in the Alpine region using descriptors derived from MODIS spectral index time series

    Science.gov (United States)

    Di Mauro, Biagio; Fava, Francesco; Busetto, Lorenzo; Crosta, Giovanni Franco; Colombo, Roberto

    2013-04-01

    In this study a method based on the analysis of MODerate-resolution Imaging Spectroradiometer (MODIS) time series is proposed to estimate the post-fire resilience of mountain vegetation (broadleaf forest and prairies) in the Italian Alps. Resilience is defined herewith as the ability of a dynamical system to counteract disturbances. It can be quantified by the amount of time the disturbed system takes to resume, in statistical terms, an ecological functionality comparable with its undisturbed behavior. Satellite images of the Normalized Difference Vegetation Index (NDVI) and of the Enhanced Vegetation Index (EVI) with spatial resolution of 250m and temporal resolution of 16 days in the 2000-2012 time period were used. Wildfire affected areas in the Lombardy region between the years 2000 and 2010 were analysed. Only large fires (affected area >40ha) were selected. For each burned area, an undisturbed adjacent control site was located. Data pre-processing consisted in the smoothing of MODIS time series for noise removal and then a double logistic function was fitted. Land surface phenology descriptors (proxies for growing season start/end/length and green biomass) were extracted in order to characterize the time evolution of the vegetation. Descriptors from a burned area were compared to those extracted from the respective control site by means of the one-way analysis of variance. According to the number of subsequent years which exhibit statistically meaningful difference between burned and control site, five classes of resilience were identified and a set of thematic maps was created for each descriptor. The same method was applied to all 84 aggregated events and to events aggregated by main land cover. EVI index results more sensitive to fire impact than NDVI index. Analysis shows that fire causes both a reduction of the biomass and a variation in the phenology of the Alpine vegetation. Results suggest an average ecosystem resilience of 6-7 years. Moreover

  13. Automatic Indexing of Documents from Journal Descriptors: A Preliminary Investigation

    OpenAIRE

    Humphrey, Susanne M.

    1999-01-01

    A new, fully automated approach for indexing documents is presented based on associating textwords in a training set of bibliographic citations with the indexing of journals. This journal-level indexing is in the form of a consistent, timely set of journal descriptors (JDs) indexing the individual journals themselves. This indexing is maintained in journal records in a serials authority database. The advantage of this novel approach is that the training set does not depend on previous manual ...

  14. An Advanced Rotation Invariant Descriptor for SAR Image Registration

    Directory of Open Access Journals (Sweden)

    Yuming Xiang

    2017-07-01

    Full Text Available The Scale-Invariant Feature Transform (SIFT algorithm and its many variants have been widely used in Synthetic Aperture Radar (SAR image registration. The SIFT-like algorithms maintain rotation invariance by assigning a dominant orientation for each keypoint, while the calculation of dominant orientation is not robust due to the effect of speckle noise in SAR imagery. In this paper, we propose an advanced local descriptor for SAR image registration to achieve rotation invariance without assigning a dominant orientation. Based on the improved intensity orders, we first divide a circular neighborhood into several sub-regions. Second, rotation-invariant ratio orientation histograms of each sub-region are proposed by accumulating the ratio values of different directions in a rotation-invariant coordinate system. The proposed descriptor is composed of the concatenation of the histograms of each sub-region. In order to increase the distinctiveness of the proposed descriptor, multiple image neighborhoods are aggregated. Experimental results on several satellite SAR images have shown an improvement in the matching performance over other state-of-the-art algorithms.

  15. Predicting enzymatic function from global binding site descriptors.

    Science.gov (United States)

    Volkamer, Andrea; Kuhn, Daniel; Rippmann, Friedrich; Rarey, Matthias

    2013-03-01

    Due to the rising number of solved protein structures, computer-based techniques for automatic protein functional annotation and classification into families are of high scientific interest. DoGSiteScorer automatically calculates global descriptors for self-predicted pockets based on the 3D structure of a protein. Protein function predictors on three levels with increasing granularity are built by use of a support vector machine (SVM), based on descriptors of 26632 pockets from enzymes with known structure and enzyme classification. The SVM models represent a generalization of the available descriptor space for each enzyme class, subclass, and substrate-specific sub-subclass. Cross-validation studies show accuracies of 68.2% for predicting the correct main class and accuracies between 62.8% and 80.9% for the six subclasses. Substrate-specific recall rates for a kinase subset are 53.8%. Furthermore, application studies show the ability of the method for predicting the function of unknown proteins and gaining valuable information for the function prediction field. Copyright © 2012 Wiley Periodicals, Inc.

  16. Log-Gabor Weber descriptor for face recognition

    Science.gov (United States)

    Li, Jing; Sang, Nong; Gao, Changxin

    2015-09-01

    The Log-Gabor transform, which is suitable for analyzing gradually changing data such as in iris and face images, has been widely used in image processing, pattern recognition, and computer vision. In most cases, only the magnitude or phase information of the Log-Gabor transform is considered. However, the complementary effect taken by combining magnitude and phase information simultaneously for an image-feature extraction problem has not been systematically explored in the existing works. We propose a local image descriptor for face recognition, called Log-Gabor Weber descriptor (LGWD). The novelty of our LGWD is twofold: (1) to fully utilize the information from the magnitude or phase feature of multiscale and orientation Log-Gabor transform, we apply the Weber local binary pattern operator to each transform response. (2) The encoded Log-Gabor magnitude and phase information are fused at the feature level by utilizing kernel canonical correlation analysis strategy, considering that feature level information fusion is effective when the modalities are correlated. Experimental results on the AR, Extended Yale B, and UMIST face databases, compared with those available from recent experiments reported in the literature, show that our descriptor yields a better performance than state-of-the art methods.

  17. Dense Descriptors for Optical Flow Estimation: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Ahmadreza Baghaie

    2017-02-01

    Full Text Available Estimating the displacements of intensity patterns between sequential frames is a very well-studied problem, which is usually referred to as optical flow estimation. The first assumption among many of the methods in the field is the brightness constancy during movements of pixels between frames. This assumption is proven to be not true in general, and therefore, the use of photometric invariant constraints has been studied in the past. One other solution can be sought by use of structural descriptors rather than pixels for estimating the optical flow. Unlike sparse feature detection/description techniques and since the problem of optical flow estimation tries to find a dense flow field, a dense structural representation of individual pixels and their neighbors is computed and then used for matching and optical flow estimation. Here, a comparative study is carried out by extending the framework of SIFT-flow to include more dense descriptors, and comprehensive comparisons are given. Overall, the work can be considered as a baseline for stimulating more interest in the use of dense descriptors for optical flow estimation.

  18. Assigning Main Orientation to an EOH Descriptor on Multispectral Images

    Directory of Open Access Journals (Sweden)

    Yong Li

    2015-07-01

    Full Text Available This paper proposes an approach to compute an EOH (edge-oriented histogram descriptor with main orientation. EOH has a better matching ability than SIFT (scale-invariant feature transform on multispectral images, but does not assign a main orientation to keypoints. Alternatively, it tends to assign the same main orientation to every keypoint, e.g., zero degrees. This limits EOH to matching keypoints between images of translation misalignment only. Observing this limitation, we propose assigning to keypoints the main orientation that is computed with PIIFD (partial intensity invariant feature descriptor. In the proposed method, SIFT keypoints are detected from images as the extrema of difference of Gaussians, and every keypoint is assigned to the main orientation computed with PIIFD. Then, EOH is computed for every keypoint with respect to its main orientation. In addition, an implementation variant is proposed for fast computation of the EOH descriptor. Experimental results show that the proposed approach performs more robustly than the original EOH on image pairs that have a rotation misalignment.

  19. Colour appearance descriptors for image browsing and retrieval

    Science.gov (United States)

    Othman, Aniza; Martinez, Kirk

    2008-01-01

    In this paper, we focus on the development of whole-scene colour appearance descriptors for classification to be used in browsing applications. The descriptors can classify a whole-scene image into various categories of semantically-based colour appearance. Colour appearance is an important feature and has been extensively used in image-analysis, retrieval and classification. By using pre-existing global CIELAB colour histograms, firstly, we try to develop metrics for whole-scene colour appearance: "colour strength", "high/low lightness" and "multicoloured". Secondly we propose methods using these metrics either alone or combined to classify whole-scene images into five categories of appearance: strong, pastel, dark, pale and multicoloured. Experiments show positive results and that the global colour histogram is actually useful and can be used for whole-scene colour appearance classification. We have also conducted a small-scale human evaluation test on whole-scene colour appearance. The results show, with suitable threshold settings, the proposed methods can describe the whole-scene colour appearance of images close to human classification. The descriptors were tested on thousands of images from various scenes: paintings, natural scenes, objects, photographs and documents. The colour appearance classifications are being integrated into an image browsing system which allows them to also be used to refine browsing.

  20. Waveform descriptor for pulse onset detection of intracranial pressure signal.

    Science.gov (United States)

    Yang, Li; Zhao, Mingxi; Peng, Chenglin; Hu, Xiao; Feng, Hua; Ji, Zhong

    2012-03-01

    We present an algorithm to identify the onset of intracranial pressure (ICP) pulses. The algorithm creates a waveform descriptor to extract the feature of each local minimum of the waveform and then identifies the onset by comparing the feature with a customized template. The waveform descriptor is derived by transforming the vectors connecting a given point and the local waveform samples around it into log-polar coordinates and ranking them into uniform bins. Using an ICP dataset consisting of 40933 normal beats and 306 segments of artifacts and noise, we investigated the performance of our algorithm (waveform descriptor, WD), global minimum within a sliding window (GM) and two other algorithms originally proposed for arterial blood pressure (ABP) signal (slope sum function, SSF and pulse waveform delineator, PUD). As a result, all the four algorithms showed good performance and WD showed overall better one. At a tolerance level of 30 ms (i.e., the predicted onset and ground truth were considered as correctly matched if the distance between the two was equal or less than 30 ms), WD achieved a sensitivity of 0.9723 and PPV of 0.9475, GM achieved a sensitivity of 0.9226 and PPV of 0.8968, PUD achieved a sensitivity of 0.9599 and PPV of 0.9327 and SSF, a sensitivity of 0.9720 and PPV of 0.9136. The evaluation indicates that the algorithms are effective for identifying the onset of ICP pulses.

  1. Assigning Main Orientation to an EOH Descriptor on Multispectral Images.

    Science.gov (United States)

    Li, Yong; Shi, Xiang; Wei, Lijun; Zou, Junwei; Chen, Fang

    2015-07-01

    This paper proposes an approach to compute an EOH (edge-oriented histogram) descriptor with main orientation. EOH has a better matching ability than SIFT (scale-invariant feature transform) on multispectral images, but does not assign a main orientation to keypoints. Alternatively, it tends to assign the same main orientation to every keypoint, e.g., zero degrees. This limits EOH to matching keypoints between images of translation misalignment only. Observing this limitation, we propose assigning to keypoints the main orientation that is computed with PIIFD (partial intensity invariant feature descriptor). In the proposed method, SIFT keypoints are detected from images as the extrema of difference of Gaussians, and every keypoint is assigned to the main orientation computed with PIIFD. Then, EOH is computed for every keypoint with respect to its main orientation. In addition, an implementation variant is proposed for fast computation of the EOH descriptor. Experimental results show that the proposed approach performs more robustly than the original EOH on image pairs that have a rotation misalignment.

  2. Sganzerla Cover

    Directory of Open Access Journals (Sweden)

    Victor da Rosa

    2014-06-01

    Full Text Available http://dx.doi.org/10.5007/2175-7917.2014v19n1p158 Neste artigo, realizo uma leitura do cinema de Rogério Sganzerla, desde o clássico O bandido da luz vermelha até os documentários filmados na década de oitenta, a partir de duas noções centrais: cover e over. Para isso, parto de uma controvérsia com o ensaio de Ismail Xavier, Alegorias do subdesenvolvimento, em que o crítico realiza uma leitura do cinema brasileiro da década de sessenta através do conceito de alegoria; depois releio uma série de textos críticos do próprio Sganzerla, publicados em Edifício Sganzerla, procurando repensar as ideias de “herói vazio” ou “cinema impuro” e sugerindo assim uma nova relação do seu cinema com o tempo e a representação; então busco articular tais ideias com certos procedimentos de vanguarda, como a falsificação, a cópia, o clichê e a colagem; e finalmente procuro mostrar que, no cinema de Sganzerla, a partir principalmente de suas reflexões sobre Orson Welles, a voz é usada de maneira a deformar a interpretação naturalista.

  3. Cover Picture.

    Science.gov (United States)

    Breuning; Ruben; Lehn; Renz; Garcia; Ksenofontov; Gütlich; Wegelius; Rissanen

    2000-07-17

    The cover picture shows how both, fine arts and science, avail themselves of a system of intertwined symbolic and iconic languages. They make use of a common set of abstracted signs to report on their results. Thus, already in 1925, Wassily Kandinsky painted a masterpiece (bottom), which now, 75 years later, might be regarded as a blueprint for a scientific project. In his painting, Kandinsky pictured a grid-shaped sign that resembles in effect an actual molecular switch. Apparently following an enigmatic protocol, the groups of Lehn and Gütlich (see p. 2504 ff. for more details) constructed a grid-type inorganic architecture that operates as a three-level magnetic switch (center) triggered by three external perturbations (p, T, hnu). The switching principle is based on the spin-crossover phenomenon of Fe(II) ions and can be monitored by Mössbauer spectroscopy (left) and magnetic measurements (rear). Maybe not by chance, the English translation of the title of the painting "signs" is a homonym of "science", since both presented works are a product of the insatiable curiosity of man and his untiring desire to recognize his existence.

  4. Shape-tailored local descriptors and their application to segmentation and tracking

    KAUST Repository

    Khan, Naeemullah

    2015-06-07

    We propose new dense descriptors for texture segmentation. Given a region of arbitrary shape in an image, these descriptors are formed from shape-dependent scale spaces of oriented gradients. These scale spaces are defined by Poisson-like partial differential equations. A key property of our new descriptors is that they do not aggregate image data across the boundary of the region, in contrast to existing descriptors based on aggregation of oriented gradients. As an example, we show how the descriptor can be incorporated in a Mumford-Shah energy for texture segmentation. We test our method on several challenging datasets for texture segmentation and textured object tracking. Experiments indicate that our descriptors lead to more accurate segmentation than non-shape dependent descriptors and the state-of-the-art in texture segmentation.

  5. A group of facial normal descriptors for recognizing 3D identical twins

    KAUST Repository

    Li, Huibin

    2012-09-01

    In this paper, to characterize and distinguish identical twins, three popular texture descriptors: i.e. local binary patterns (LBPs), gabor filters (GFs) and local gabor binary patterns (LGBPs) are employed to encode the normal components (x, y and z) of the 3D facial surfaces of identical twins respectively. A group of facial normal descriptors are thus achieved, including Normal Local Binary Patterns descriptor (N-LBPs), Normal Gabor Filters descriptor (N-GFs) and Normal Local Gabor Binary Patterns descriptor (N-LGBPs). All these normal encoding based descriptors are further fed into sparse representation classifier (SRC) for identification. Experimental results on the 3D TEC database demonstrate that these proposed normal encoding based descriptors are very discriminative and efficient, achieving comparable performance to the best of state-of-the-art algorithms. © 2012 IEEE.

  6. Descritores de dor pós-hemorroidectomia Descriptores de dolor post-hemorroidectomia Post-hemorrhoidectomy pain descriptors

    Directory of Open Access Journals (Sweden)

    Hortense Priscilla

    2005-04-01

    Full Text Available Estudo conduzido com o objetivo de comparar as escalas derivadas de julgamentos de diferenças e verificar a estabilidade e a concordância das estimativas da atribuição dos descritores à dor pós-operatória julgadas por três diferentes amostras. Participaram do estudo 19 sujeitos submetidos a hemorroidectomia, os quais foram divididos aleatoriamente em três grupos (Grupo C, T e F, que receberam via endovenosa cetoprofeno 100 mg, tenoxicam 40 mg ou soro fisiológico 0,9%, antes do início da cirurgia. A tarefa de cada participante foi assinalar um escore, de 1 a 7, a cada descritor de dor sentida na primeira queixa após a cirurgia. Os descritores atribuídos à dor pós-operatória foram avaliados pelo método psicofísico de estimação de categorias. Os resultados obtidos foram: os descritores de maior atribuição para o Grupo C foram intensa, insuportável e terrível; para o Grupo T, foram intensa, tremenda e insuportável e para o Grupo F, foram insuportável, intensa e terrível.Los objetivos de este trabajo fueron comparar las escalas derivadas de juzgamientos de diferencias y verificar la estabilidad y la concordancia de las estimativas de la atribución de los descriptores de dolor post-operatorio juzgadas por tres diferentes muestras. Participaron del estudio 19 sujetos sometidos a hemorroidectomia, estos fueron divididos aleatoriamente en tres grupos (Grupo C, T e F, que recibieron vía endovenosa cetoprofeno 100 mg, tenoxicam 40 mg el suero fisiológico 0,9% antes del inicio de la cirugía. La tarea de cada participante fue aseñalar un "score", entre 1 y 7, a cada descriptor de dolor sentido en la primera queja después de la cirugía. Los descriptores atribuídos al dolor post-operatório fueron evaluados por el método psicofísico de estimación de categorías. Los resultados obtenidos fueron: los descriptores de mayor atribución para el Grupo C fueron intenso, insuportable y terrible; para el Grupo T fueron intenso

  7. Practical Dyspnea Assessment: Relationship Between the 0-10 Numerical Rating Scale and the Four-Level Categorical Verbal Descriptor Scale of Dyspnea Intensity.

    Science.gov (United States)

    Wysham, Nicholas G; Miriovsky, Benjamin J; Currow, David C; Herndon, James E; Samsa, Gregory P; Wilcock, Andrew; Abernethy, Amy P

    2015-10-01

    Measurement of dyspnea is important for clinical care and research. To characterize the relationship between the 0-10 Numerical Rating Scale (NRS) and four-level categorical Verbal Descriptor Scale (VDS) for dyspnea assessment. This was a substudy of a double-blind randomized controlled trial comparing palliative oxygen to room air for relief of refractory breathlessness in patients with life-limiting illness. Dyspnea was assessed with both a 0-10 NRS and a four-level categorical VDS over the one-week trial. NRS and VDS responses were analyzed in cross section and longitudinally. Relationships between NRS and VDS responses were portrayed using descriptive statistics and visual representations. Two hundred twenty-six participants contributed responses. At baseline, mild and moderate levels of breathlessness were reported by 41.9% and 44.6% of participants, respectively. NRS scores demonstrated increasing mean and median levels for increasing VDS intensity, from a mean (SD) of 0.6 (±1.04) for VDS none category to 8.2 (1.4) for VDS severe category. The Spearman correlation coefficient was strong at 0.78 (P < 0.0001). Based on the distribution of NRS scores within VDS categories, we calculated test characteristics of two different cutpoint models. Both models yielded 75% correct translations from NRS to VDS; however, Model A was more sensitive for moderate or greater dyspnea, with fewer misses downcoded. There is strong correlation between VDS and NRS measures for dyspnea. Proposed practical cutpoints for the relationship between the dyspnea VDS and NRS are 0 for none, 1-4 for mild, 5-8 for moderate, and 9-10 for severe. Copyright © 2015 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  8. Pattern and intensity of human impact on coral reefs depend on depth along the reef profile and on the descriptor adopted

    Science.gov (United States)

    Nepote, Ettore; Bianchi, Carlo Nike; Chiantore, Mariachiara; Morri, Carla; Montefalcone, Monica

    2016-09-01

    Coral reefs are threatened by multiple global and local disturbances. The Maldives, already heavily hit by the 1998 mass bleaching event, are currently affected also by growing tourism and coastal development that may add to global impacts. Most of the studies investigating effects of local disturbances on coral reefs assessed the response of communities along a horizontal distance from the impact source. This study investigated the status of a Maldivian coral reef around an island where an international touristic airport has been recently (2009-2011) built, at different depths along the reef profile (5-20 m depth) and considering the change in the percentage of cover of five different non-taxonomic descriptors assessed through underwater visual surveys: hard corals, soft corals, other invertebrates, macroalgae and abiotic attributes. Eight reefs in areas not affected by any coastal development were used as controls and showed a reduction of hard coral cover and an increase of abiotic attributes (i.e. sand, rock, coral rubble) at the impacted reef. However, hard coral cover, the most widely used descriptor of coral reef health, was not sufficient on its own to detect subtle indirect effects that occurred down the reef profile. Selecting an array of descriptors and considering different depths, where corals may find a refuge from climate impacts, could guide the efforts of minimising local human pressures on coral reefs.

  9. Logo Matching for Document Image Retrieval Using SIFT Descriptors

    Directory of Open Access Journals (Sweden)

    Boyapati Bharathidevi

    2017-02-01

    Full Text Available In current trends the logos are playing a vital role in industrial and all commercial applications. Fundamentally the logo is defined as it’s a graphic entity which contains colors textures, shapes and text etc., which is organized in some special visible format. But unfortunately it is very difficult thing to save their brand logos from duplicates. In practical world there are several systems available for logo reorganization and detection with different kinds of requirements. Two dimensional global descriptors are used for logo matching and reorganization. The concept of Shape descriptors based on Shape context and the global descriptors are based on the logo contours. There is an algorithm which is implemented for logo detection is based on partial spatial context and spatial spectral saliency (SSS. The SSS is able to keep away from the confusion effect of background and also speed up the process of logo detection. All such methods are useful only when the logo is visible completely without noise and not subjected to change. We contribute, through this paper, to the design of a novel variation framework able to match and recognize multiple instances of multiple reference logos in image archives. Reference logos and test images are seen as constellations of local features (interest points, regions, etc. and matched by minimizing an energy function mixing: 1 a fidelity term that measures the quality of feature matching, 2 a neighborhood criterion that captures feature co-occurrence geometry, and 3 a regularization term that controls the smoothness of the matching solution. We also introduce a detection/recognition procedure and study its theoretical consistency.

  10. Rapid multi-modality preregistration based on SIFT descriptor.

    Science.gov (United States)

    Chen, Jian; Tian, Jie

    2006-01-01

    This paper describes the scale invariant feature transform (SIFT) method for rapid preregistration of medical image. This technique originates from Lowe's method wherein preregistration is achieved by matching the corresponding keypoints between two images. The computational complexity has been reduced when we applied SIFT preregistration method before refined registration due to its O(n) exponential calculations. The features of SIFT are highly distinctive and invariant to image scaling and rotation, and partially invariant to change in illumination and contrast, it is robust and repeatable for cursorily matching two images. We also altered the descriptor so our method can deal with multimodality preregistration.

  11. Image Retrieval Method Using Top-surf Descriptor

    CERN Document Server

    Ji, Ye

    2011-01-01

    This report presents the results and details of a content-based image retrieval project using the Top-surf descriptor. The experimental results are preliminary, however, it shows the capability of deducing objects from parts of the objects or from the objects that are similar. This paper uses a dataset consisting of 1200 images of which 800 images are equally divided into 8 categories, namely airplane, beach, motorbike, forest, elephants, horses, bus and building, while the other 400 images are randomly picked from the Internet. The best results achieved are from building category.

  12. Deep Self-Convolutional Activations Descriptor for Dense Cross-Modal Correspondence

    OpenAIRE

    Kim, Seungryong; Min, Dongbo; Lin, Stephen; Sohn, Kwanghoon

    2016-01-01

    We present a novel descriptor, called deep self-convolutional activations (DeSCA), designed for establishing dense correspondences between images taken under different imaging modalities, such as different spectral ranges or lighting conditions. Motivated by descriptors based on local self-similarity (LSS), we formulate a novel descriptor by leveraging LSS in a deep architecture, leading to better discriminative power and greater robustness to non-rigid image deformations than state-of-the-ar...

  13. Novel structural descriptors for automated colon cancer detection and grading.

    Science.gov (United States)

    Rathore, Saima; Hussain, Mutawarra; Aksam Iftikhar, Muhammad; Jalil, Abdul

    2015-09-01

    The histopathological examination of tissue specimens is necessary for the diagnosis and grading of colon cancer. However, the process is subjective and leads to significant inter/intra observer variation in diagnosis as it mainly relies on the visual assessment of histopathologists. Therefore, a reliable computer-aided technique, which can automatically classify normal and malignant colon samples, and determine grades of malignant samples, is required. In this paper, we propose a novel colon cancer diagnostic (CCD) system, which initially classifies colon biopsy images into normal and malignant classes, and then automatically determines the grades of colon cancer for malignant images. To this end, various novel structural descriptors, which mathematically model and quantify the variation among the structure of normal colon tissues and malignant tissues of various cancer grades, have been employed. Radial basis function (RBF) kernel of support vector machines (SVM) has been employed as classifier in order to classify/grade colon samples based on these descriptors. The proposed system has been tested on 92 malignant and 82 normal colon biopsy images. The classification performance has been measured in terms of various performance measures, and quite promising performance has been observed. Compared with previous techniques, the proposed system has demonstrated better cancer detection (classification accuracy=95.40%) and grading (classification accuracy=93.47%) capability. Therefore, the proposed CCD system can provide a reliable second opinion to the histopathologists.

  14. Descriptor Learning via Supervised Manifold Regularization for Multioutput Regression.

    Science.gov (United States)

    Zhen, Xiantong; Yu, Mengyang; Islam, Ali; Bhaduri, Mousumi; Chan, Ian; Li, Shuo

    2016-06-08

    Multioutput regression has recently shown great ability to solve challenging problems in both computer vision and medical image analysis. However, due to the huge image variability and ambiguity, it is fundamentally challenging to handle the highly complex input-target relationship of multioutput regression, especially with indiscriminate high-dimensional representations. In this paper, we propose a novel supervised descriptor learning (SDL) algorithm for multioutput regression, which can establish discriminative and compact feature representations to improve the multivariate estimation performance. The SDL is formulated as generalized low-rank approximations of matrices with a supervised manifold regularization. The SDL is able to simultaneously extract discriminative features closely related to multivariate targets and remove irrelevant and redundant information by transforming raw features into a new low-dimensional space aligned to targets. The achieved discriminative while compact descriptor largely reduces the variability and ambiguity for multioutput regression, which enables more accurate and efficient multivariate estimation. We conduct extensive evaluation of the proposed SDL on both synthetic data and real-world multioutput regression tasks for both computer vision and medical image analysis. Experimental results have shown that the proposed SDL can achieve high multivariate estimation accuracy on all tasks and largely outperforms the algorithms in the state of the arts. Our method establishes a novel SDL framework for multioutput regression, which can be widely used to boost the performance in different applications.

  15. Face liveness detection using shearlet-based feature descriptors

    Science.gov (United States)

    Feng, Litong; Po, Lai-Man; Li, Yuming; Yuan, Fang

    2016-07-01

    Face recognition is a widely used biometric technology due to its convenience but it is vulnerable to spoofing attacks made by nonreal faces such as photographs or videos of valid users. The antispoof problem must be well resolved before widely applying face recognition in our daily life. Face liveness detection is a core technology to make sure that the input face is a live person. However, this is still very challenging using conventional liveness detection approaches of texture analysis and motion detection. The aim of this paper is to propose a feature descriptor and an efficient framework that can be used to effectively deal with the face liveness detection problem. In this framework, new feature descriptors are defined using a multiscale directional transform (shearlet transform). Then, stacked autoencoders and a softmax classifier are concatenated to detect face liveness. We evaluated this approach using the CASIA Face antispoofing database and replay-attack database. The experimental results show that our approach performs better than the state-of-the-art techniques following the provided protocols of these databases, and it is possible to significantly enhance the security of the face recognition biometric system. In addition, the experimental results also demonstrate that this framework can be easily extended to classify different spoofing attacks.

  16. Multichannel linear descriptors analysis for sustained attention-related electroencephalography.

    Science.gov (United States)

    Liu, Tian; Yan, Nan; Chen, Yanni; Wang, Jue

    2013-08-07

    This study investigated the differences in brain functional state between sustained attention and ignoring task conditions using the electroencephalography in association with sustained attention to response task (SART) performance. Multichannel electroencephalography data were obtained from 10 male healthy volunteers while performing the SART. Three multichannel linear descriptors, that is spatial complexity (Ω), field strength (Σ), and frequency of field changes (Φ), were applied to analyze three frequency bands (θ, α, and β) for sustained attention and ignoring task conditions. The experimental results showed that participants had a significantly lower Ω value in the θ and α band in the SART state. The Σ value was significantly higher in each frequency band of interest in almost all region of interest areas during SART performance. In addition, the Φ value was significantly lower in the θ band and significantly higher in the β band during the sustained attention condition. The results indicated that multichannel linear descriptors could show the differences in brain functions between sustained attention and ignoring task conditions, and might be used to evaluate disorders with an attentional dysfunction.

  17. Modified SIFT Descriptors for Face Recognition under Different Emotions

    Directory of Open Access Journals (Sweden)

    Nirvair Neeru

    2016-01-01

    Full Text Available The main goal of this work is to develop a fully automatic face recognition algorithm. Scale Invariant Feature Transform (SIFT has sparingly been used in face recognition. In this paper, a Modified SIFT (MSIFT approach has been proposed to enhance the recognition performance of SIFT. In this paper, the work is done in three steps. First, the smoothing of the image has been done using DWT. Second, the computational complexity of SIFT in descriptor calculation is reduced by subtracting average from each descriptor instead of normalization. Third, the algorithm is made automatic by using Coefficient of Correlation (CoC instead of using the distance ratio (which requires user interaction. The main achievement of this method is reduced database size, as it requires only neutral images to store instead of all the expressions of the same face image. The experiments are performed on the Japanese Female Facial Expression (JAFFE database, which indicates that the proposed approach achieves better performance than SIFT based methods. In addition, it shows robustness against various facial expressions.

  18. Reshaping Plant Biology: Qualitative and Quantitative Descriptors for Plant Morphology

    Science.gov (United States)

    Balduzzi, Mathilde; Binder, Brad M.; Bucksch, Alexander; Chang, Cynthia; Hong, Lilan; Iyer-Pascuzzi, Anjali S.; Pradal, Christophe; Sparks, Erin E.

    2017-01-01

    An emerging challenge in plant biology is to develop qualitative and quantitative measures to describe the appearance of plants through the integration of mathematics and biology. A major hurdle in developing these metrics is finding common terminology across fields. In this review, we define approaches for analyzing plant geometry, topology, and shape, and provide examples for how these terms have been and can be applied to plants. In leaf morphological quantifications both geometry and shape have been used to gain insight into leaf function and evolution. For the analysis of cell growth and expansion, we highlight the utility of geometric descriptors for understanding sepal and hypocotyl development. For branched structures, we describe how topology has been applied to quantify root system architecture to lend insight into root function. Lastly, we discuss the importance of using morphological descriptors in ecology to assess how communities interact, function, and respond within different environments. This review aims to provide a basic description of the mathematical principles underlying morphological quantifications. PMID:28217137

  19. Object Detection with Vocabularies of Space-time Descriptors

    Directory of Open Access Journals (Sweden)

    Y. Hernandez-Heredia

    2012-11-01

    Full Text Available This paper presents a novel framework for objects detection in security and broadcast videos. Our method assumes thatobject classes are unknown in advance and exploit the temporal-space properties of the videos for the creation of avocabulary that describes these classes. Local space-time features have recently became a popular video representationfor action recognition and object detection. Several methods for feature localization and description have been proposedin the literature and promising recognition results were demonstrated for a number of action classes.In this work we propose the use of different kinds of descriptors for the creation of vocabularies for different detectionobject task. For a better description of the videos we carry out a background model, tryring to clean up and follow theareas where there are objects. The points of interest in the videos to characterize the objects are calculated with atemporary variant of the famous Harris corner detector. With the descriptors obtained from the points of interest, avocabulary is realized usingthe kinds of videos we want to train. Then we obtained the frequency histogramsbetween the videos for training and the vocabulary so, with a binary classifier obtain the trained classes and followingthe same procedure without the vocabulary realized the detection and monitoring of the objects.The new method presented is also compared with a state of the art method, obtaining better results in both accuracyand false object rejection.

  20. Object tracking on mobile devices using binary descriptors

    Science.gov (United States)

    Savakis, Andreas; Quraishi, Mohammad Faiz; Minnehan, Breton

    2015-03-01

    With the growing ubiquity of mobile devices, advanced applications are relying on computer vision techniques to provide novel experiences for users. Currently, few tracking approaches take into consideration the resource constraints on mobile devices. Designing efficient tracking algorithms and optimizing performance for mobile devices can result in better and more efficient tracking for applications, such as augmented reality. In this paper, we use binary descriptors, including Fast Retina Keypoint (FREAK), Oriented FAST and Rotated BRIEF (ORB), Binary Robust Independent Features (BRIEF), and Binary Robust Invariant Scalable Keypoints (BRISK) to obtain real time tracking performance on mobile devices. We consider both Google's Android and Apple's iOS operating systems to implement our tracking approach. The Android implementation is done using Android's Native Development Kit (NDK), which gives the performance benefits of using native code as well as access to legacy libraries. The iOS implementation was created using both the native Objective-C and the C++ programing languages. We also introduce simplified versions of the BRIEF and BRISK descriptors that improve processing speed without compromising tracking accuracy.

  1. Object classfication from RGB-D images using depth context kernel descriptors

    DEFF Research Database (Denmark)

    Pan, Hong; Olsen, Søren Ingvor; Zhu, Yaping

    2015-01-01

    Context cue is important in object classification. By embedding the depth context cue of image attributes into kernel descriptors, we propose a new set of depth image descriptors called depth context kernel descriptors (DCKD) for RGB-D based object classification. The motivation of DCKD is to use...... the depth consistency of image attributes defined within a neighboring region to improve the robustness of descriptor matching in the kernel space. Moreover, a novel joint spatial-depth pooling (JSDP) scheme, which further partitions image sub-regions using the depth cue and pools features in both 2D image...

  2. Enhancing Volumetric Bouligand-Minkowski Fractal Descriptors by using Functional Data Analysis

    CERN Document Server

    Florindo, João Batista; Bruno, Odemir Martinez; 10.1142/S0129183111016701

    2012-01-01

    This work proposes and study the concept of Functional Data Analysis transform, applying it to the performance improving of volumetric Bouligand-Minkowski fractal descriptors. The proposed transform consists essentially in changing the descriptors originally defined in the space of the calculus of fractal dimension into the space of coefficients used in the functional data representation of these descriptors. The transformed decriptors are used here in texture classification problems. The enhancement provided by the FDA transform is measured by comparing the transformed to the original descriptors in terms of the correctness rate in the classification of well known datasets.

  3. Propuesta de descriptores para Acca sellowiana (Berg. Burret

    Directory of Open Access Journals (Sweden)

    María Puppo

    2014-12-01

    Full Text Available Guayabo del país o goiaba serrana [Acca sellowiana (Berg. Burret] es uno de los recursos fitogenéticos subutilizados más valiosos de Uruguay y Brasil. Este árbol de fruto comestible, es endémico de una estrecha región sudamericana que abarca el noreste uruguayo y sur de Brasil, donde su cultivo se limita al uso doméstico o a pequeños huertos comerciales. El uso de los materiales de la especie se ve limitado por el desconocimiento de la diversidad presente tanto en poblaciones naturales como en materiales cultivados. El objetivo de este trabajo fue la elaboración de una lista de descriptores que permita la caracterización y evaluación de los materiales para la conservación, uso sostenible e incorporación de diversidad en los programas de mejoramiento genético. Se elaboró una lista preliminar de 41 descriptores morfo-fenológicos de hoja, flor y fruto, que se aplicó in situ a 204 individuos pertenecientes a cuatro poblaciones silvestres del noreste del Uruguay. Con el método de Máxima Verosimilitud Restringida se estimaron los componentes de la varianza entre poblaciones (s²P, entre individuos dentro de poblaciones (s²I(P, entre muestras dentro de individuo (s²M(IP y sus intervalos de confianza utilizando un Modelo Lineal Mixto. Para la determinación del poder discriminante de las variables cuantitativas se adoptó como criterio estadístico la comparación de IC (límite inferior ICs²I(P>límite superior ICs²M(IP y se calculó la razón entre s²I(P/s²M(IP. Para las variables cualitativas se calculó el estadístico F para la determinación de las diferencias significativas entre individuos con el objetivo de identificar descriptores discriminantes de individuos. También se determinaron las variables que discriminan poblaciones. Se validaron siete descriptores cualitativos (forma de fruto, posición de los sépalos, color de pulpa, color interno de la cáscara, dureza de cáscara, clases de distancia estigma-estambres y

  4. Land Cover - Minnesota Land Cover Classification System

    Data.gov (United States)

    Minnesota Department of Natural Resources — Land cover data set based on the Minnesota Land Cover Classification System (MLCCS) coding scheme. This data was produced using a combination of aerial photograph...

  5. Descriptor Based Analysis of Digital 3D Shapes

    DEFF Research Database (Denmark)

    Welnicka, Katarzyna

    challenges. One such challenge, which is addressed in this thesis, is to develop computational methods for classifying shapes which are in agreement with the human way of understanding and classifying shapes. In this dissertation we first present a shape descriptor based on the process of diffusion......Analysis and processing of 3D digital shapes is a significant research area with numerous medical, industrial, and entertainment applications which has gained enormously in importance as optical scanning modalities have started to make acquired 3D geometry commonplace. The area holds many......, in conjunction with the method of Reeb graphs for skeletonization, it is an effective tool for generating scale dependent skeletons of shapes represented as 3D triangle meshes. The second part of the thesis aims at capturing the style phenomenon. The style of an object is easily recognized by humans...

  6. Retrieval of Remote Sensing Images with Pattern Spectra Descriptors

    Directory of Open Access Journals (Sweden)

    Petra Bosilj

    2016-12-01

    Full Text Available The rapidly increasing volume of visual Earth Observation data calls for effective content based image retrieval solutions, specifically tailored for their high spatial resolution and heterogeneous content. In this paper, we address this issue with a novel local implementation of the well-known morphological descriptors called pattern spectra. They are computationally efficient histogram-like structures describing the global distribution of arbitrarily defined attributes of connected image components. Besides employing pattern spectra for the first time in this context, our main contribution lies in their dense calculation, at a local scale, thus enabling their combination with sophisticated visual vocabulary strategies. The Merced Landuse/Landcover dataset has been used for comparing the proposed strategy against alternative global and local content description methods, where the introduced approach is shown to yield promising performances.

  7. Generalized PID observer design for descriptor linear systems.

    Science.gov (United States)

    Wu, Ai-Guo; Duan, Guang-Ren; Fu, Yan-Ming

    2007-10-01

    A type of generalized proportional-integral-derivative observers is proposed for descriptor linear systems. Based on a general parametric solution to a type of generalized Sylvester matrix equations, a parametric design approach for such observers is established. The proposed approach provides parameterizations for all the observer gain matrices, gives the parametric expression for the corresponding left eigenvector matrix of the observer system matrix, realizes the elimination of impulsive behaviors, and guarantees the regularity of the observer system. The design method can offer all the degrees of design freedom, which can be utilized to achieve various desired system specifications and performances. In addition, a numerical example is employed to show the design procedure and illustrate the effect of the presented approach.

  8. INFORMATION RETRIEVAL SYSTEM USING MULTIWORDS EXPRESSIONS (MWE AS DESCRIPTORS

    Directory of Open Access Journals (Sweden)

    Edson Marchetti da Silva

    2012-08-01

    Full Text Available This paper aims to propose an alternative method for retrieving documents using Multiwords Expressions (MWE extracted from a document base to be used as descriptors in search of an Information Retrieval System (IRS. In this sense, unlike methods that consider the text as a set of words, bag of words, we propose a method that takes into account the characteristics of the physical structure of the document in the extraction process of MWE. From this set of terms comparing pre-processed using an exhaustive algorithmic technique proposed by the authors with the results obtained for thirteen different measures of association statistics generated by the software Ngram Statistics Package (NSP. To perform this experiment was set up with a corpus of documents in digital format

  9. Learning physical descriptors for materials science by compressed sensing

    Science.gov (United States)

    Ghiringhelli, Luca M.; Vybiral, Jan; Ahmetcik, Emre; Ouyang, Runhai; Levchenko, Sergey V.; Draxl, Claudia; Scheffler, Matthias

    2017-02-01

    The availability of big data in materials science offers new routes for analyzing materials properties and functions and achieving scientific understanding. Finding structure in these data that is not directly visible by standard tools and exploitation of the scientific information requires new and dedicated methodology based on approaches from statistical learning, compressed sensing, and other recent methods from applied mathematics, computer science, statistics, signal processing, and information science. In this paper, we explain and demonstrate a compressed-sensing based methodology for feature selection, specifically for discovering physical descriptors, i.e., physical parameters that describe the material and its properties of interest, and associated equations that explicitly and quantitatively describe those relevant properties. As showcase application and proof of concept, we describe how to build a physical model for the quantitative prediction of the crystal structure of binary compound semiconductors.

  10. Optimal $RH_2$-- and $RH_\\infty$--Approximation of Unstable Descriptor Systems

    CERN Document Server

    Köhler, Marcus

    2012-01-01

    We consider the following problem. Given an unstable continuous--time descriptor system with transfer function $G$, find a stable descriptor system whose transfer function is the best approximation of $G$ in the spaces $RH_2$ and $RH_\\infty$, respectively. Explicit optimal solutions are presented under consideration of numerical issues.

  11. Region descriptors for automatic classification of small sea targets in infrared video

    NARCIS (Netherlands)

    Mouthaan, M.M.; Broek, S.P. van den; Hendriks, E.A.; Schwering, P.B.W.

    2011-01-01

    We evaluate the performance of different key-point detectors and region descriptors when used for automatic classification of small sea targets in infrared video. In our earlier research performed on this subject as well as in other literature, many different region descriptors have been proposed. H

  12. 75 FR 2879 - Use of Tobacco Marketing Descriptors to Convey Modified Risk; Request for Comments

    Science.gov (United States)

    2010-01-19

    ... information will be used to further FDA's efforts to reduce misleading and deceptive advertising practices..., labeling, or advertising of which uses the descriptors `light', `mild', or `low' or similar descriptors... label, labeling, or advertising of modified risk tobacco products. III. Comments Interested persons may...

  13. Molecular design and QSARs/QSPRs with molecular descriptors family.

    Science.gov (United States)

    Bolboacă, Sorana D; Jäntschi, Lorentz; Diudea, Mircea V

    2013-06-01

    The aim of the present paper is to present the methodology of the molecular descriptors family (MDF) as an integrative tool in molecular modeling and its abilities as a multivariate QSAR/QSPR modeling tool. An algorithm for extracting useful information from the topological and geometrical representation of chemical compounds was developed and integrated to calculate MDF members. The MDF methodology was implemented and the software is available online (http://l.academicdirect.org/Chemistry/SARs/MDF_SARs/). This integrative tool was developed in order to maximize performance, functionality, efficiency and portability. The MDF methodology is able to provide reliable and valid multiple linear regression models. Furthermore, in many cases, the MDF models were better than the published results in the literature in terms of correlation coefficients (statistically significant Steiger's Z test at a significance level of 5%) and/or in terms of values of information criteria and Kubinyi function. The MDF methodology developed and implemented as a platform for investigating and characterizing quantitative relationships between the chemical structure and the activity/property of active compounds was used on more than 50 study cases. In almost all cases, the methodology allowed obtaining of QSAR/QSPR models improved in explanatory power of structure-activity and structure-property relationships. The algorithms applied in the computation of geometric and topological descriptors (useful in modeling physicochemical or biological properties of molecules) and those used in searching for reliable and valid multiple linear regression models certain enrich the pool of low-cost low-time drug design tools.

  14. A new region descriptor for multi-modal medical image registration and region detection.

    Science.gov (United States)

    Xiaonan Wan; Dongdong Yu; Feng Yang; Caiyun Yang; Chengcai Leng; Min Xu; Jie Tian

    2015-08-01

    Establishing accurate anatomical correspondences plays a critical role in multi-modal medical image registration and region detection. Although many features based registration methods have been proposed to detect these correspondences, they are mostly based on the point descriptor which leads to high memory cost and could not represent local region information. In this paper, we propose a new region descriptor which depicts the features in each region, instead of in each point, as a vector. First, feature attributes of each point are extracted by a Gabor filter bank combined with a gradient filter. Then, the region descriptor is defined as the covariance of feature attributes of each point inside the region, based on which a cost function is constructed for multi-modal image registration. Finally, our proposed region descriptor is applied to both multi-modal region detection and similarity metric measurement in multi-modal image registration. Experiments demonstrate the feasibility and effectiveness of our proposed region descriptor.

  15. Weighted Multi-Scale Image Matching Based on Harris-Sift Descriptor

    Directory of Open Access Journals (Sweden)

    Can Sun

    2013-10-01

    Full Text Available According to the rotational invariance of Harris corner detectorand the robustness of Sift descriptor. An improved Harris-Sift corner descriptor was proposed. At first, the algorithm given multi-scale strategy to Harris corner, improved corner counting method and removed redundant points at the same time, then, the corner was directly applied to low-pass Gaussian filter image. Based on the histogram of Sift feature descriptor, generates a new 128-dimensional feature vector descriptor by multi-scale Gauss weighted.Through the above, Harris corner detectorand Sift descriptorwas normalizedin the scale layer and gradient features. The experiment results indicated that, the improved corner descriptorcomprised both advantage of Harris corner detection and Sift feature descriptor. The method reduced the computation time and the false match rate, which could be validly applied to the robotstereo vision matching andthree-dimensional reconstruction.      

  16. Descriptors for ions and ion-pairs for use in linear free energy relationships.

    Science.gov (United States)

    Abraham, Michael H; Acree, William E

    2016-01-22

    The determination of Abraham descriptors for single ions is reviewed, and equations are given for the partition of single ions from water to a number of solvents. These ions include permanent anions and cations and ionic species such as carboxylic acid anions, phenoxide anions and protonated base cations. Descriptors for a large number of ions and ionic species are listed, and equations for the prediction of Abraham descriptors for ionic species are given. The application of descriptors for ions and ionic species to physicochemical processes is given; these are to water-solvent partitions, HPLC retention data, immobilised artificial membranes, the Finkelstein reaction and diffusion in water. Applications to biological processes include brain permeation, microsomal degradation of drugs, skin permeation and human intestinal absorption. The review concludes with a section on the determination of descriptors for ion-pairs.

  17. Contextual descriptors and neural networks for scene analysis in VHR SAR images

    Science.gov (United States)

    Del Frate, Fabio; Picchiani, Matteo; Falasco, Alessia; Schiavon, Giovanni

    2016-10-01

    The development of SAR technology during the last decade has made it possible to collect a huge amount of data over many regions of the world. In particular, the availability of SAR images from different sensors, with metric or sub-metric spatial resolution, offers novel opportunities in different fields as land cover, urban monitoring, soil consumption etc. On the other hand, automatic approaches become crucial for the exploitation of such a huge amount of information. In such a scenario, especially if single polarization images are considered, the main issue is to select appropriate contextual descriptors, since the backscattering coefficient of a single pixel may not be sufficient to classify an object on the scene. In this paper a comparison among three different approaches for contextual features definition is presented so as to design optimum procedures for VHR SAR scene understanding. The first approach is based on Gray Level Co- Occurrence Matrix since it is widely accepted and several studies have used it for land cover classification with SAR data. The second approach is based on the Fourier spectra and it has been already proposed with positive results for this kind of problems, the third one is based on Auto-associative Neural Networks which have been already proven effective for features extraction from polarimetric SAR images. The three methods are evaluated in terms of the accuracy of the classified scene when the features extracted using each method are considered as input to a neural network classificator and applied on different Cosmo-SkyMed spotlight products.

  18. The sEDA(=) and pEDA(=) descriptors of the double bonded substituent effect.

    Science.gov (United States)

    Mazurek, Andrzej; Dobrowolski, Jan Cz

    2013-05-14

    New descriptors of the double bonded substituent effect, sEDA(=) and pEDA(=), were constructed based on quantum chemical calculations and NBO methodology. They show to what extent the σ and π electrons are donated to or withdrawn from the substituted system by a double bonded substituent. The new descriptors differ from descriptors of the classical substituent effect for which the pz orbital of the ipso carbon atom is engaged in the π-electron system of the two neighboring atoms in the ring. For double bonded substituents, the pz orbital participates in double bond formation with only one external atom. Moreover, the external double bond forces localization of the double bond system of the ring, significantly changing the core molecule. We demonstrated good agreement between our descriptors and the Weinhold and Landis' "natural σ and π-electronegativities": so far only descriptors allowing for evaluation of the substitution effect by a double bonded atom. The equivalency between descriptors constructed for 5- and 6-membered model structures as well as linear dependence/independence of the constructed parameters was discussed. Some interrelations between sEDA(=) and pEDA(=) and the other descriptors of (hetero)cyclic systems such as aromaticity and electron density in the ring and bond critical points were also examined.

  19. Performance enhancement of the branch length similarity entropy descriptor for shape recognition by introducing critical points

    Science.gov (United States)

    Lee, Sang-Hee; Kang, Seung-Ho

    2016-10-01

    In previous studies, we showed that the branch length similarity (BLS) entropy profile could be used successfully for the recognition of shapes such as battle tanks, facial expressions, and butterflies. In the present study, we introduce critical points defined as a set of distinguishing points with high curvature to the BLS entropy profile in order to improve the shape recognition. In order to generate a given number of critical points from the shape, we propose a critical point detection method. Furthermore, we show the invariant properties of the BLS entropy descriptor. To evaluate the effects of critical points on the shape recognition of the BLS entropy descriptor, we performed a butterfly classification experiment against a real image data set, and we conducted performance comparisons with other point detection methods. In addition, the performance of the BLS entropy descriptor computed using the critical points was compared with those of other well-known descriptors such as the Fourier descriptor using three machine learning techniques, the Bayesian classifier, the multi-layer perceptron and the support vector machine. The results show that the BLS entropy descriptor outperforms other well-known descriptors.

  20. A comparative study on the molecular descriptors for predicting drug-likeness of small molecules

    Science.gov (United States)

    Mishra, Hrishikesh; Singh, Nitya; Lahiri, Tapobrata; Misra, Krishna

    2009-01-01

    Screening of “ drug-like” molecule from the molecular database produced through high throughput techniques and their large repositories requires robust classification. In our work, a set of heuristically chosen nine molecular descriptors including four from Lipinski's rule, were used as classification parameter for screening “drug-like” molecules. The robustness of classification was compared with four fundamental descriptors of Lipinski. Back propagation neural network based classifier was applied on a database of 60000 molecules for classification of, “ drug-like” and “non drug-like” molecules. Classification result using nine descriptors showed high classification accuracy of 96.1% in comparison to that using four Lipinski's descriptors which yielded an accuracy of 82.48%. Also a significant decrease of false positives resulted while using nine descriptors causing a sharp 18% increase of specificity of classification. From this study it appeared that Lipinski's descriptors which mainly deal with pharmacokinetic properties of molecules form the basis for identification of “drug-like” molecules that can be substantially improved by adding more descriptors representing pharmaco­dynamics properties of molecules. PMID:19707563

  1. Community Energy Systems and the Law of Public Utilities. Volume Twenty-six. Mississippi

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, D.A.; Weaver, C.L.

    1981-01-01

    A detailed description is presented of the laws and programs of the State of Mississippi governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  2. Pulmonary Valve Replacement : Twenty-Six Years of Experience With Mechanical Valvar Prostheses

    NARCIS (Netherlands)

    Freling, Hendrik G.; van Slooten, Ymkje J.; van Melle, Joost P.; Ebels, Tjark; Hoendermis, Elke S.; Berger, Rolf M. F.; Hillege, Hans L.; Waterbolk, Tjalling W.; van Veldhuisen, Dirk J.; Willems, Tineke P.; Pieper, Petronella G.

    2015-01-01

    BACKGROUND: Although the thromboembolic risk after pulmonary valve replacement (PVR) with mechanical valves is presumed to be high, recent studies suggest promising short-term and mid-term results. However, large studies reporting long-term mortality and valve-related complications are missing. METH

  3. Twenty six cases of human Fasciola gigantica infection in Dali,Yunnan province

    Institute of Scientific and Technical Information of China (English)

    陈木新

    2013-01-01

    Objective To investigate the epidemic situation,clinical symptom,diagnosis and epidemiological characteristics of human Fasciola gigantica infection in Dali,Yunnan province. It will also provide a scientific basis for fasciolosis control and prevention. Methods Epidemic

  4. Recurrent sigmoid volvulus associated with eventration of diaphragm in a twenty-six-year-old man.

    Science.gov (United States)

    Prabhu, Shailesh Mukund; Venkatesan, Bhuvaneswari; Shetty, Gurucharan; Narula, Mahender Kaur; Chauhan, Udit; Udiya, Alok Kumar

    2015-04-01

    Recurrent sigmoid volvulus is a clinical entity characterized by recurrent episodes of partial or complete sigmoid volvulus. Although it is commonly seen in the elderly, it can be occasionally seen in younger patients. Patients with recurrent partial sigmoid volvulus are relatively asymptomatic or present with mild abdominal pain. Early diagnosis and treatment is essential to prevent conversion to acute gangrenous volvulus. We present a case of recurrent partial sigmoid volvulus in association with eventration of diaphragm in a 26-year-old man.

  5. Status of Twenty-Six Innovative Education Practices in Iowa Elementary Schools.

    Science.gov (United States)

    Sloan, Harold; Loomer, Bradley M.

    This study represents an attempt to identify the status of change in Iowa elementary schools. In addition to providing current data reflecting the prevalence of 26 selected educational practices, this study report includes data concerning the adoption process, proposers, influencers, degree of staff involvement, preservice and inservice training…

  6. Quantitative structure-retention relationships of pesticides in reversed-phase high-performance liquid chromatography based on WHIM and GETAWAY molecular descriptors

    Energy Technology Data Exchange (ETDEWEB)

    D' Archivio, Angelo Antonio [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi di L' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy)], E-mail: darchivi@univaq.it; Maggi, Maria Anna; Mazzeo, Pietro; Ruggieri, Fabrizio [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi di L' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy)

    2008-11-03

    The ability of the Weighted Holistic Invariant Molecular (WHIM) and GEometry, Topology, and Atom-Weights AssemblY (GETAWAY) descriptors to represent the effect of molecular structure on the retention of pesticides in reversed-phase high-performance liquid chromatography (RP-HPLC) is investigated. To this end, two retention data sets previously collected in water-acetonitrile mobile phase are re-examined. The first data set (data-set-1) consists of retention data of 26 neutral compounds belonging to widely used pesticide classes, collected within the mobile phase composition range 40-65% (v/v) acetonitrile. The second data set (data-set-2) describes retention of phenoxy acid herbicides and structurally related compounds (benzoic acid and phenylacetic acid derivatives), as a whole covering the pK{sub a} range 2.3-4.3, as a function of mobile phase composition, ranging between 30 and 70% (v/v) acetonitrile, and pH, ranging between 2 and 5. For each data set, the mobile phase attributes are combined with WHIM or GETAWAY descriptors into 'mixed' predictive models in order to attempt retention modelling within the whole mobile phase composition range of analytical interest. Six- or seven-dimensional multilinear models, preliminarily selected using a genetic algorithm, were improved using a multi-layer artificial neural network (ANN) learned by back propagation. ANN performance was tested on three molecules not used in the learning stage and by leave-more-out cross validation. The results reveal that while WHIM descriptors seem not adequate to model retention of solutes of data-set-1, GETAWAY descriptors provide a satisfactory retention model. On the other hand WHIM and GETAWAY descriptors applied to data-set-2 provide a similar performance, even if slightly worse as compared with the above case. Accuracy of retention modelling in these cases is comparable or slightly poorer as compared with the results previously obtained by combining quantum chemical

  7. Quantitative structure-retention relationships of pesticides in reversed-phase high-performance liquid chromatography based on WHIM and GETAWAY molecular descriptors.

    Science.gov (United States)

    D'Archivio, Angelo Antonio; Maggi, Maria Anna; Mazzeo, Pietro; Ruggieri, Fabrizio

    2008-11-03

    The ability of the Weighted Holistic Invariant Molecular (WHIM) and GEometry, Topology, and Atom-Weights AssemblY (GETAWAY) descriptors to represent the effect of molecular structure on the retention of pesticides in reversed-phase high-performance liquid chromatography (RP-HPLC) is investigated. To this end, two retention data sets previously collected in water-acetonitrile mobile phase are re-examined. The first data set (data-set-1) consists of retention data of 26 neutral compounds belonging to widely used pesticide classes, collected within the mobile phase composition range 40-65% (v/v) acetonitrile. The second data set (data-set-2) describes retention of phenoxy acid herbicides and structurally related compounds (benzoic acid and phenylacetic acid derivatives), as a whole covering the pK(a) range 2.3-4.3, as a function of mobile phase composition, ranging between 30 and 70% (v/v) acetonitrile, and pH, ranging between 2 and 5. For each data set, the mobile phase attributes are combined with WHIM or GETAWAY descriptors into "mixed" predictive models in order to attempt retention modelling within the whole mobile phase composition range of analytical interest. Six- or seven-dimensional multilinear models, preliminarily selected using a genetic algorithm, were improved using a multi-layer artificial neural network (ANN) learned by back propagation. ANN performance was tested on three molecules not used in the learning stage and by leave-more-out cross validation. The results reveal that while WHIM descriptors seem not adequate to model retention of solutes of data-set-1, GETAWAY descriptors provide a satisfactory retention model. On the other hand WHIM and GETAWAY descriptors applied to data-set-2 provide a similar performance, even if slightly worse as compared with the above case. Accuracy of retention modelling in these cases is comparable or slightly poorer as compared with the results previously obtained by combining quantum chemical descriptors or usual

  8. Kernel sparse coding method for automatic target recognition in infrared imagery using covariance descriptor

    Science.gov (United States)

    Yang, Chunwei; Yao, Junping; Sun, Dawei; Wang, Shicheng; Liu, Huaping

    2016-05-01

    Automatic target recognition in infrared imagery is a challenging problem. In this paper, a kernel sparse coding method for infrared target recognition using covariance descriptor is proposed. First, covariance descriptor combining gray intensity and gradient information of the infrared target is extracted as a feature representation. Then, due to the reason that covariance descriptor lies in non-Euclidean manifold, kernel sparse coding theory is used to solve this problem. We verify the efficacy of the proposed algorithm in terms of the confusion matrices on the real images consisting of seven categories of infrared vehicle targets.

  9. Impulsive Controllability/Observability for Interconnected Descriptor Systems with Two Subsystems

    Directory of Open Access Journals (Sweden)

    Qingling Zhang

    2015-01-01

    Full Text Available The problem of decentralized impulse controllability/observability for large-scale interconnected descriptor systems with two subsystems by derivative feedback is studied. Necessary conditions for the existence of a derivative feedback controller for the first subsystem of the large-scale interconnected descriptor systems ensuring the second subsystem to be impulse controllable and impulse observable are derived, respectively. Based on the results, a derivative feedback controller for the first subsystem of the large-scale interconnected descriptor systems is constructed easily such that the second subsystem is impulse controllable or impulse observable. Finally, examples are given to illustrate the effectiveness of the results obtained in this paper.

  10. Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

    DEFF Research Database (Denmark)

    Meng-Lund, Helena; Friis, Natascha; van de Weert, Marco

    2017-01-01

    A quantitative structure-property relationship (QSPR) between protein stability and the physicochemical properties of excipients was investigated to enable a more rational choice of stabilizing excipients than prior knowledge. The thermal transition temperature and aggregation time were determined...... analysis was applied to correlate the descriptors with the experimental results. It was possible to identify descriptors, i.e. amino acids properties, with a positive influence on either transition temperature or aggregation onset time, or both. A high number of hydrogen bond acceptor moieties was the most....... The QSPR shows good correlation between calculated molecular descriptors and the measured stabilizing effect of amino acids on lysozyme....

  11. Unevenness Point Descriptor for Terrain Analysis in Mobile Robot Applications

    Directory of Open Access Journals (Sweden)

    Mauro Bellone

    2013-07-01

    Full Text Available In recent years, the use of imaging sensors that produce a three-dimensional representation of the environment has become an efficient solution to increase the degree of perception of autonomous mobile robots. Accurate and dense 3D point clouds can be generated from traditional stereo systems and laser scanners or from the new generation of RGB-D cameras, representing a versatile, reliable and cost-effective solution that is rapidly gaining interest within the robotics community. For autonomous mobile robots, it is critical to assess the traversability of the surrounding environment, especially when driving across natural terrain. In this paper, a novel approach to detect traversable and non-traversable regions of the environment from a depth image is presented that could enhance mobility and safety through integration with localization, control and planning methods. The proposed algorithm is based on the analysis of the normal vector of a surface obtained through Principal Component Analysis and it leads to the definition of a novel, so defined, Unevenness Point Descriptor. Experimental results, obtained with vehicles operating in indoor and outdoor environments, are presented to validate this approach.

  12. A dynamic appearance descriptor approach to facial actions temporal modeling.

    Science.gov (United States)

    Jiang, Bihan; Valstar, Michel; Martinez, Brais; Pantic, Maja

    2014-02-01

    Both the configuration and the dynamics of facial expressions are crucial for the interpretation of human facial behavior. Yet to date, the vast majority of reported efforts in the field either do not take the dynamics of facial expressions into account, or focus only on prototypic facial expressions of six basic emotions. Facial dynamics can be explicitly analyzed by detecting the constituent temporal segments in Facial Action Coding System (FACS) Action Units (AUs)-onset, apex, and offset. In this paper, we present a novel approach to explicit analysis of temporal dynamics of facial actions using the dynamic appearance descriptor Local Phase Quantization from Three Orthogonal Planes (LPQ-TOP). Temporal segments are detected by combining a discriminative classifier for detecting the temporal segments on a frame-by-frame basis with Markov Models that enforce temporal consistency over the whole episode. The system is evaluated in detail over the MMI facial expression database, the UNBC-McMaster pain database, the SAL database, the GEMEP-FERA dataset in database-dependent experiments, in cross-database experiments using the Cohn-Kanade, and the SEMAINE databases. The comparison with other state-of-the-art methods shows that the proposed LPQ-TOP method outperforms the other approaches for the problem of AU temporal segment detection, and that overall AU activation detection benefits from dynamic appearance information.

  13. Scale Invariant Gabor Descriptor-Based Noncooperative Iris Recognition

    Directory of Open Access Journals (Sweden)

    Du Yingzi

    2010-01-01

    Full Text Available Abstract A new noncooperative iris recognition method is proposed. In this method, the iris features are extracted using a Gabor descriptor. The feature extraction and comparison are scale, deformation, rotation, and contrast-invariant. It works with off-angle and low-resolution iris images. The Gabor wavelet is incorporated with scale-invariant feature transformation (SIFT for feature extraction to better extract the iris features. Both the phase and magnitude of the Gabor wavelet outputs were used in a novel way for local feature point description. Two feature region maps were designed to locally and globally register the feature points and each subregion in the map is locally adjusted to the dilation/contraction/deformation. We also developed a video-based non-cooperative iris recognition system by integrating video-based non-cooperative segmentation, segmentation evaluation, and score fusion units. The proposed method shows good performance for frontal and off-angle iris matching. Video-based recognition methods can improve non-cooperative iris recognition accuracy.

  14. Scale Invariant Gabor Descriptor-based Noncooperative Iris Recognition

    Directory of Open Access Journals (Sweden)

    Zhi Zhou

    2010-01-01

    Full Text Available A new noncooperative iris recognition method is proposed. In this method, the iris features are extracted using a Gabor descriptor. The feature extraction and comparison are scale, deformation, rotation, and contrast-invariant. It works with off-angle and low-resolution iris images. The Gabor wavelet is incorporated with scale-invariant feature transformation (SIFT for feature extraction to better extract the iris features. Both the phase and magnitude of the Gabor wavelet outputs were used in a novel way for local feature point description. Two feature region maps were designed to locally and globally register the feature points and each subregion in the map is locally adjusted to the dilation/contraction/deformation. We also developed a video-based non-cooperative iris recognition system by integrating video-based non-cooperative segmentation, segmentation evaluation, and score fusion units. The proposed method shows good performance for frontal and off-angle iris matching. Video-based recognition methods can improve non-cooperative iris recognition accuracy.

  15. Phenotypic characterization of glioblastoma identified through shape descriptors

    Science.gov (United States)

    Chaddad, Ahmad; Desrosiers, Christian; Toews, Matthew

    2016-03-01

    This paper proposes quantitatively describing the shape of glioblastoma (GBM) tissue phenotypes as a set of shape features derived from segmentations, for the purposes of discriminating between GBM phenotypes and monitoring tumor progression. GBM patients were identified from the Cancer Genome Atlas, and quantitative MR imaging data were obtained from the Cancer Imaging Archive. Three GBM tissue phenotypes are considered including necrosis, active tumor and edema/invasion. Volumetric tissue segmentations are obtained from registered T1˗weighted (T1˗WI) postcontrast and fluid-attenuated inversion recovery (FLAIR) MRI modalities. Shape features are computed from respective tissue phenotype segmentations, and a Kruskal-Wallis test was employed to select features capable of classification with a significance level of p < 0.05. Several classifier models are employed to distinguish phenotypes, where a leave-one-out cross-validation was performed. Eight features were found statistically significant for classifying GBM phenotypes with p <0.05, orientation is uninformative. Quantitative evaluations show the SVM results in the highest classification accuracy of 87.50%, sensitivity of 94.59% and specificity of 92.77%. In summary, the shape descriptors proposed in this work show high performance in predicting GBM tissue phenotypes. They are thus closely linked to morphological characteristics of GBM phenotypes and could potentially be used in a computer assisted labeling system.

  16. Evaluating Learner Autonomy: A Dynamic Model with Descriptors

    Directory of Open Access Journals (Sweden)

    Maria Giovanna Tassinari

    2012-03-01

    Full Text Available Every autonomous learning process should entail an evaluation of the learner’s competencies for autonomy. The dynamic model of learner autonomy described in this paper is a tool designed in order to support the self-assessment and evaluation of learning competencies and to help both learners and advisors to focus on relevant aspects of the learning process. The dynamic model accounts for cognitive, metacognitive, action-oriented and affective components of learner autonomy and provides descriptors of learners’ attitudes, competencies and behaviors. It is dynamic in order to allow learners to focus on their own needs and goals.The model (http://www.sprachenzentrum.fuberlin.de/v/autonomiemodell/index.html has been validated in several workshops with experts at the Université Nancy 2, France and at the Freie Universität Berlin, Germany and tested by students, advisors and teachers. It is currently used at the Centre for Independent Language Learning at the Freie Universität Berlin for language advising. Learners can freely choose the components they would like to assess themselves in. Their assessment is then discussed in an advising session, where the learner and the advisor can compare their perspectives, focus on single aspects of the leaning process and set goals for further learning. The students’ feedback gathered in my PhD investigation shows that they are able to benefit from this evaluation; their awareness, self-reflection and decision-making in the autonomous learning process improved.

  17. 商业养老保险:农民的购买意愿及其影响因素--来自新疆13个地州市726位农民调查的数据%Commercial Endowment Insuran ce:Peasanst ’ Purchase Intention andi ts Influence Fatco rs---Based on Seven Hundred and Twenty-six Peasants ’ Survey Data Coming from Thirteen Districts of Sinkiang

    Institute of Scientific and Technical Information of China (English)

    于长永; 李敏

    2015-01-01

    基于2012年新疆13个地州市726位农民的调查数据,利用二元Logistic回归模型,分析农民的商业养老保险购买意愿及其影响因素,利用Multiple Response 分析方法,分析农民不愿意购买商业养老保险的原因。结果显示,农民的商业养老保险购买意愿尽管仍较低,但与2005年的调查结果相比,农民的购买意愿已经有了大幅度提高;文化程度、社会流动、家庭储蓄规模、商业养老保险的市场可及性和新型农村社会养老保险试点情况,显著影响了农民的商业养老保险购买意愿;没有钱购买、保险费太高、不了解保险产品和不相信保险公司是农民不愿意购买商业养老保险的四个主要原因,其中,排在首位的不是农民没有钱购买,而是农民不了解保险产品。因此,拓展农村商业养老保险市场的首要任务不是尽快提高农民的收入水平,而是如何尽可能地提高农民对商业养老保险的了解程度。%Abts ract:This paper analyses peasants'purchase intention and its influence factors by binary logistic model and analyses the reasons why peasants didn't want to buy endowment insurance by the method of multiple response based on seven hundred and twenty-six peasants’ survey data coming from thirteen districts in Sinkiang.The results showed that peasants’ purchase intention is still low, but peasants'purchase intention had significant-ly increased compared with the survey result of 2005.These independent variables containing degree of education, social mobility, family savings scale , market accessibility of commercial endowment insurance and pilot situation of rural social endowment insurance influenced peasants'purchase intention markedly.No money to pay for it, unreasonable insurance product price, unfamiliar with insurance products and unbelieving the insurance company is the four chief reasons why peasants didn’t want to buy commercial endowment

  18. What Medicare Covers

    Science.gov (United States)

    ... What Part A covers Medicare Part A hospital insurance covers inpatient hospital care, skilled nursing facility, hospice, lab tests, surgery, ... Medicare Covers Drug Coverage (Part D) Supplements & Other Insurance Claims & ... doctors, providers, hospitals & plans Where can I get covered medical items? ...

  19. A Novel Fast and Robust Binary Affine Invariant Descriptor for Image Matching

    Directory of Open Access Journals (Sweden)

    Xiujie Qu

    2014-01-01

    Full Text Available As the current binary descriptors have disadvantages of high computational complexity, no affine invariance, and the high false matching rate with viewpoint changes, a new binary affine invariant descriptor, called BAND, is proposed. Different from other descriptors, BAND has an irregular pattern, which is based on local affine invariant region surrounding a feature point, and it has five orientations, which are obtained by LBP effectively. Ultimately, a 256 bits binary string is computed by simple random sampling pattern. Experimental results demonstrate that BAND has a good matching result in the conditions of rotating, image zooming, noising, lighting, and small-scale perspective transformation. It has better matching performance compared with current mainstream descriptors, while it costs less time.

  20. Unsupervised selection of informative descriptors in QSAR study of anti-HIV activities of HEPT derivatives

    DEFF Research Database (Denmark)

    Bagheri, Saeed; Omidikia, Nematollah; Kompany-Zareh, Mohsen

    2013-01-01

    With the increasing ease of measuring and calculating multiple descriptors per molecule in quantitative structure-activity relationship, the importance of variable selection for data reduction and improving interpretability is gaining importance. While variable selection has been extensively...

  1. Predicting partitioning of volatile organic compounds from air into plant cuticular matrix by quantum chemical descriptors

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Based on theoretical linear solvation energy relationship and quantum chemical descriptors computed by AM1 Hamiltonian, a new model is developed to predict the partitioning of some volatile organic compounds between the plant cuticular matrix and air.

  2. A novel image zooming method based on sparse representation of Weber’s law descriptor

    Directory of Open Access Journals (Sweden)

    Liping Wang

    2016-12-01

    Full Text Available A novel image zooming algorithm based on sparse representation of Weber’s law descriptor is proposed in this article. It is known that features of low resolution can be extracted using four one-dimensional filters convoluting with low resolution patches. Weber’s law descriptor can well deal with local feature, so we extract low-resolution image feature replacing one-dimensional with Weber’s law descriptor in the four filters. In addition, fractional calculus can deal with nonlocal information such as texture. For avoiding small complex component when the size of image is not an odd integer, we modify the extending image method used by Bai, so it can save lots of calculation. The proposed approach combining the Weber’s law descriptor with fractional calculus achieves a very good performance. Experimental results show that our method can well eliminate jagged effect when up-sampling an image and is robustness to noise.

  3. Visualization and processing of higher order descriptors for multi-valued data

    CERN Document Server

    Schultz, Thomas

    2015-01-01

    Modern imaging techniques and computational simulations yield complex multi-valued data that require higher-order mathematical descriptors. This book addresses topics of importance when dealing with such data, including frameworks for image processing, visualization, and statistical analysis of higher-order descriptors. It also provides examples of the successful use of higher-order descriptors in specific applications and a glimpse of the next generation of diffusion MRI. To do so, it combines contributions on new developments, current challenges in this area, and state-of-the-art surveys.   Compared to the increasing importance of higher-order descriptors in a range of applications, tools for analysis and processing are still relatively hard to come by. Even though application areas such as medical imaging, fluid dynamics, and structural mechanics are very different in nature they face many shared challenges. This book provides an interdisciplinary perspective on this topic with contributions from key rese...

  4. Chemical descriptors, convexity and structure of density matrices in molecular systems

    CERN Document Server

    Bochicchio, Roberto C

    2015-01-01

    The electron energy and density matrices in molecular systems are convex in respect of the number of particles. So that, the chemical descriptors based on their derivatives present the hamper of discontinuities for isolated systems and consequently higher order derivatives are undefined. The introduction of the interaction between the physical domain with an environment induces a coherent structure for the density matrix in the grand-canonical formulation suppressing the discontinuities leading to the proper definitions of the descriptors.

  5. Minimum Energy Control of Descriptor Fractional Discrete–Time Linear Systems with Two Different Fractional Orders

    Directory of Open Access Journals (Sweden)

    Sajewski Łukasz

    2017-03-01

    Full Text Available Reachability and minimum energy control of descriptor fractional discrete-time linear systems with different fractional orders are addressed. Using the Weierstrass–Kronecker decomposition theorem of the regular pencil, a solution to the state equation of descriptor fractional discrete-time linear systems with different fractional orders is given. The reachability condition of this class of systems is presented and used for solving the minimum energy control problem. The discussion is illustrated with numerical examples.

  6. Audio Environment Recognition using Zero Crossing Features and MPEG-7 Descriptors

    OpenAIRE

    Saleh Al-Zhrani; Mubarak AlQahtani

    2010-01-01

    Problem statement: This study investigated zero crossing features and selected MPEG-7 audio descriptors for environment sound recognition applications such as audio forensics. Approach: The study implemented several experiments focusing on the problems of environment recognition from audio particularly for forensic applications. Results: It was investigated the effect of the temporal zero crossing feature as well as selected MPEG-7 audio low level descriptors on environment sound recognition....

  7. An Efficient Method for Landscape Image Classification and Matching Based on MPEG-7 Descriptors

    OpenAIRE

    2011-01-01

    In this thesis, an efficient approach for landscape image classification and matching system based on the MPEG-7 (Moving Picture Expert group) color and shape descriptor. Image classification is the task of deciding whether an image landscape or not. These classifications use the dominant color descriptor method for finding the dominant color in the image. In DCD we examine whole image pixel values. The pixel value contains Red, Green and Blue color values in the RGB color model. After calcul...

  8. A comparative study on the molecular descriptors for predicting drug-likeness of small molecules

    OpenAIRE

    Mishra, Hrishikesh; Singh, Nitya; Lahiri, Tapobrata; Misra, Krishna

    2009-01-01

    Screening of “ drug-like” molecule from the molecular database produced through high throughput techniques and their large repositories requires robust classification. In our work, a set of heuristically chosen nine molecular descriptors including four from Lipinski's rule, were used as classification parameter for screening “drug-like” molecules. The robustness of classification was compared with four fundamental descriptors of Lipinski. Back propagation neural network based classifier was a...

  9. Descriptor Trends in Texture Classification for Material Recognition

    Directory of Open Access Journals (Sweden)

    Hayder Ayad

    2015-08-01

    Full Text Available Recent rapid growth in the demand for technology and image investigation in many applications, such as image retrieval systems and Visual Object Categorization (VOC, effective management of these applications has become crucial. Computer vision and its various applications are a primary focus of research. Content-based image retrieval is considered an extremely challenging issue and has remained an open research area. Obviously, the main challenge associated with this kind of research is the gap between the low-level features and the richness of the semantic concept of the human mind. This problem is called the semantic gap. Several methods have been proposed to increase the performance of the system and reduce the semantic gap. These proposed techniques make use of either global or local features or a combination of both global and local features on one side and the visual content and keyword-based retrieval on the other side. However, the aim of this study is to provide a constructive critique of the algorithms used in extracting the low-level features, either globally or locally or as a combination of both. In addition, it identifies the factors that can affect the low-level features that lead to the semantic gap. As well as, proposed a new framework to improve the Gabor filter and the edge histogram limitations. Finally, recommendations are made for the choice of the descriptors used to describe the low-level features, both locally and globally, depending on the area of limitations or drawbacks of the previous state-of-the-art research.

  10. pK(a) prediction from "Quantum Chemical Topology" descriptors.

    Science.gov (United States)

    Harding, A P; Wedge, D C; Popelier, P L A

    2009-08-01

    Knowing the pK(a) of a compound gives insight into many properties relevant to many industries, in particular the pharmaceutical industry during drug development processes. In light of this, we have used the theory of Quantum Chemical Topology (QCT), to provide ab initio descriptors that are able to accurately predict pK(a) values for 228 carboxylic acids. This Quantum Topological Molecular Similarity (QTMS) study involved the comparison of 5 increasingly more expensive levels of theory to conclude that HF/6-31G(d) and B3LYP/6-311+G(2d,p) provided an accurate representation of the compounds studies. We created global and subset models for the carboxylic acids using Partial Least Square (PLS), Support Vector Machines (SVM), and Radial Basis Function Neural Networks (RBFNN). The models were extensively validated using 4-, 7-, and 10-fold cross-validation, with the validation sets selected based on systematic and random sampling. HF/6-31G(d) in conjunction with SVM provided the best statistics when taking into account the large increase in CPU time required to optimize the geometries at the B3LYP/6-311+G(2d,p) level. The SVM models provided an average q(2) value of 0.886 and an RMSE value of 0.293 for all the carboxylic acids, a q(2) of 0.825 and RMSE of 0.378 for the ortho-substituted acids, a q(2) of 0.923 and RMSE of 0.112 for the para- and meta-substituted acids, and a q(2) of 0.906 and RMSE of 0.268 for the aliphatic acids. Our method compares favorably to ACD/Laboratories, VCCLAB, SPARC, and ChemAxon's pK(a) prediction software based of the RMSE calculated by the leave-one-out method.

  11. Fast global interactive volume segmentation with regional supervoxel descriptors

    Science.gov (United States)

    Luengo, Imanol; Basham, Mark; French, Andrew P.

    2016-03-01

    In this paper we propose a novel approach towards fast multi-class volume segmentation that exploits supervoxels in order to reduce complexity, time and memory requirements. Current methods for biomedical image segmentation typically require either complex mathematical models with slow convergence, or expensive-to-calculate image features, which makes them non-feasible for large volumes with many objects (tens to hundreds) of different classes, as is typical in modern medical and biological datasets. Recently, graphical models such as Markov Random Fields (MRF) or Conditional Random Fields (CRF) are having a huge impact in different computer vision areas (e.g. image parsing, object detection, object recognition) as they provide global regularization for multiclass problems over an energy minimization framework. These models have yet to find impact in biomedical imaging due to complexities in training and slow inference in 3D images due to the very large number of voxels. Here, we define an interactive segmentation approach over a supervoxel space by first defining novel, robust and fast regional descriptors for supervoxels. Then, a hierarchical segmentation approach is adopted by training Contextual Extremely Random Forests in a user-defined label hierarchy where the classification output of the previous layer is used as additional features to train a new classifier to refine more detailed label information. This hierarchical model yields final class likelihoods for supervoxels which are finally refined by a MRF model for 3D segmentation. Results demonstrate the effectiveness on a challenging cryo-soft X-ray tomography dataset by segmenting cell areas with only a few user scribbles as the input for our algorithm. Further results demonstrate the effectiveness of our method to fully extract different organelles from the cell volume with another few seconds of user interaction.

  12. GENETIC DIVERSITY IN ACCESSIONS OF Stylosanthes spp. USING MORPHOAGRONOMIC DESCRIPTORS

    Directory of Open Access Journals (Sweden)

    RONALDO SIMÃO DE OLIVEIRA

    2016-01-01

    Full Text Available The great diversity of plants in the Brazilian Semiarid environment represents a vital natural resource for the human populations of these areas. Many of these plants have been subject to extractivism and among these, the species of the genus Stylosanthes , which have occurrence in this region, show great potential, however, studies on this topic are limited, and little is known about the existing variability among these plants. Therefore, further study is necessary, to facilitate the development of cultivars. This might reduce the scarcity of fodder supply in this region, but to commence a plant breeding programme, it is essential to identify genetic variability. Therefore, this study evaluated 25 accessions of Stylosanthes spp., to identify the most suitable candidates to be parents in a plant breeding programme for the semiarid region of the state of Bahia. Two experiments were carried out in different sites in an experimental design of randomized blocks with four replicates, with a spacing of 3.0 × 8.0 m. A large amount of genetic diversity was observed among accessions and the genotypes BGF 08 - 007, BGF 08 - 016, BGF 08 - 015 and BGF 08 - 021 were the most divergent in the overall evaluation. For the structuring of segregating populations, it is recommended to combine the genotypes BGF 08 - 016, BGF 08 - 015, BGF 08 - 007 and BGF 08 - 006, and for the interspecific crosses, a hybrid from the accession BGF - 024 with the accessions BGF 08 - 016 or BGF 08 - 015. This might generate superior individuals for mass descriptors, which are the most important for animal forage breeding.

  13. BCL::EMAS — Enantioselective Molecular Asymmetry Descriptor for 3D-QSAR

    Directory of Open Access Journals (Sweden)

    Mariusz Butkiewicz

    2012-08-01

    Full Text Available Stereochemistry is an important determinant of a molecule’s biological activity. Stereoisomers can have different degrees of efficacy or even opposing effects when interacting with a target protein. Stereochemistry is a molecular property difficult to represent in 2D-QSAR as it is an inherently three-dimensional phenomenon. A major drawback of most proposed descriptors for 3D-QSAR that encode stereochemistry is that they require a heuristic for defining all stereocenters and rank-ordering its substituents. Here we propose a novel 3D-QSAR descriptor termed Enantioselective Molecular ASymmetry (EMAS that is capable of distinguishing between enantiomers in the absence of such heuristics. The descriptor aims to measure the deviation from an overall symmetric shape of the molecule. A radial-distribution function (RDF determines a signed volume of tetrahedrons of all triplets of atoms and the molecule center. The descriptor can be enriched with atom-centric properties such as partial charge. This descriptor showed good predictability when tested with a dataset of thirty-one steroids commonly used to benchmark stereochemistry descriptors (r2 = 0.89, q2 = 0.78. Additionally, EMAS improved enrichment of 4.38 versus 3.94 without EMAS in a simulated virtual high-throughput screening (vHTS for inhibitors and substrates of cytochrome P450 (PUBCHEM AID891.

  14. A Color-Texture-Structure Descriptor for High-Resolution Satellite Image Classification

    Directory of Open Access Journals (Sweden)

    Huai Yu

    2016-03-01

    Full Text Available Scene classification plays an important role in understanding high-resolution satellite (HRS remotely sensed imagery. For remotely sensed scenes, both color information and texture information provide the discriminative ability in classification tasks. In recent years, substantial performance gains in HRS image classification have been reported in the literature. One branch of research combines multiple complementary features based on various aspects such as texture, color and structure. Two methods are commonly used to combine these features: early fusion and late fusion. In this paper, we propose combining the two methods under a tree of regions and present a new descriptor to encode color, texture and structure features using a hierarchical structure-Color Binary Partition Tree (CBPT, which we call the CTS descriptor. Specifically, we first build the hierarchical representation of HRS imagery using the CBPT. Then we quantize the texture and color features of dense regions. Next, we analyze and extract the co-occurrence patterns of regions based on the hierarchical structure. Finally, we encode local descriptors to obtain the final CTS descriptor and test its discriminative capability using object categorization and scene classification with HRS images. The proposed descriptor contains the spectral, textural and structural information of the HRS imagery and is also robust to changes in illuminant color, scale, orientation and contrast. The experimental results demonstrate that the proposed CTS descriptor achieves competitive classification results compared with state-of-the-art algorithms.

  15. Performance Enhancement of Patch-based Descriptors for Image Copy Detection

    Directory of Open Access Journals (Sweden)

    Junaid Baber

    2016-03-01

    Full Text Available Images have become main sources for the informa-tion, learning, and entertainment, but due to the advancement and progress in multimedia technologies, millions of images are shared on Internet daily which can be easily duplicated and redistributed. Distribution of these duplicated and transformed images cause a lot of problems and challenges such as piracy, redundancy, and content-based image indexing and retrieval. To address these problems, copy detection system based on local features are widely used. Initially, keypoints are detected and represented by some robust descriptors. The descriptors are computed over the affine patches around the keypoints, these patches should be repeatable under photometric and geometric transformations. However, there exist two main challenges with patch based descriptors, (1 the affine patch over the keypoint can produce similar descriptors under entirely different scene or the context which causes “ambiguity”, and (2 the descriptors are not enough “distinctive” under image noise. Due to these limitations, the copy detection systems suffer in performance. We present a framework that makes descriptor more distinguishable and robust by influencing them with the texture and gradients in vicinity. The experimental evaluation on keypoints matching and image copy detection under severe transformations shows the effectiveness of the proposed framework.

  16. Convolution Comparison Pattern: An Efficient Local Image Descriptor for Fingerprint Liveness Detection.

    Directory of Open Access Journals (Sweden)

    Carsten Gottschlich

    Full Text Available We present a new type of local image descriptor which yields binary patterns from small image patches. For the application to fingerprint liveness detection, we achieve rotation invariant image patches by taking the fingerprint segmentation and orientation field into account. We compute the discrete cosine transform (DCT for these rotation invariant patches and attain binary patterns by comparing pairs of two DCT coefficients. These patterns are summarized into one or more histograms per image. Each histogram comprises the relative frequencies of pattern occurrences. Multiple histograms are concatenated and the resulting feature vector is used for image classification. We name this novel type of descriptor convolution comparison pattern (CCP. Experimental results show the usefulness of the proposed CCP descriptor for fingerprint liveness detection. CCP outperforms other local image descriptors such as LBP, LPQ and WLD on the LivDet 2013 benchmark. The CCP descriptor is a general type of local image descriptor which we expect to prove useful in areas beyond fingerprint liveness detection such as biological and medical image processing, texture recognition, face recognition and iris recognition, liveness detection for face and iris images, and machine vision for surface inspection and material classification.

  17. TDSIFT: a new descriptor for 2D and 3D ear recognition

    Science.gov (United States)

    Chen, Long; Mu, Zhichun; Nan, Bingfei; Zhang, Yi; Yang, Ruyin

    2017-02-01

    Descriptor is the key of any image-based recognition algorithm. For ear recognition, conventional descriptors are either based on 2D data or 3D data. 2D images provide rich texture information and human ear is a 3D surface that could offer shape information. It also inspires us that 2D data is more robust against occlusion while 3D data shows more robustness against illumination variation and pose variation. In this paper, we introduce a novel Texture and Depth Scale Invariant Feature Transform (TDSIFT) descriptor to encode 2D and 3D local features for ear recognition. Compared to the original Scale Invariant Feature Transform (SIFT) descriptor, the proposed TDSIFT shows its superiority by fusing 2D local information and 3D local information. Firstly, keypoints are detected and described on texture images. Then, 3D information of the keypoints located on the corresponding depth images is added to form the TDSIFT descriptor. Finally, a local feature based classification algorithm is adopted to identify ear samples by TDSIFT. Experimental results on a benchmark dataset demonstrate the feasibility and effectiveness of our proposed descriptor. The rank-1 recognition rate achieved on a gallery of 415 persons is 95.9% and the time involved in the computation is satisfactory compared to state-of-the-art methods.

  18. Histogram of oriented phase (HOP): a new descriptor based on phase congruency

    Science.gov (United States)

    Ragb, Hussin K.; Asari, Vijayan K.

    2016-05-01

    In this paper we present a low level image descriptor called Histogram of Oriented Phase based on phase congruency concept and the Principal Component Analysis (PCA). Since the phase of the signal conveys more information regarding signal structure than the magnitude, the proposed descriptor can precisely identify and localize image features over the gradient based techniques, especially in the regions affected by illumination changes. The proposed features can be formed by extracting the phase congruency information for each pixel in the image with respect to its neighborhood. Histograms of the phase congruency values of the local regions in the image are computed with respect to its orientation. These histograms are concatenated to construct the Histogram of Oriented Phase (HOP) features. The dimensionality of HOP features is reduced using PCA algorithm to form HOP-PCA descriptor. The dimensionless quantity of the phase congruency leads the HOP-PCA descriptor to be more robust to the image scale variations as well as contrast and illumination changes. Several experiments were performed using INRIA and DaimlerChrysler datasets to evaluate the performance of the HOP-PCA descriptor. The experimental results show that the proposed descriptor has better detection performance and less error rates than a set of the state of the art feature extraction methodologies.

  19. Effective structural descriptors for natural and engineered radioactive waste confinement barriers

    Science.gov (United States)

    Lemmens, Laurent; Rogiers, Bart; De Craen, Mieke; Laloy, Eric; Jacques, Diederik; Huysmans, Marijke; Swennen, Rudy; Urai, Janos L.; Desbois, Guillaume

    2017-04-01

    The microstructure of a radioactive waste confinement barrier strongly influences its flow and transport properties. Numerical flow and transport simulations for these porous media at the pore scale therefore require input data that describe the microstructure as accurately as possible. To date, no imaging method can resolve all heterogeneities within important radioactive waste confinement barrier materials as hardened cement paste and natural clays at the micro scale (nm-cm). Therefore, it is necessary to merge information from different 2D and 3D imaging methods using porous media reconstruction techniques. To qualitatively compare the results of different reconstruction techniques, visual inspection might suffice. To quantitatively compare training-image based algorithms, Tan et al. (2014) proposed an algorithm using an analysis of distance. However, the ranking of the algorithm depends on the choice of the structural descriptor, in their case multiple-point or cluster-based histograms. We present here preliminary work in which we will review different structural descriptors and test their effectiveness, for capturing the main structural characteristics of radioactive waste confinement barrier materials, to determine the descriptors to use in the analysis of distance. The investigated descriptors are particle size distributions, surface area distributions, two point probability functions, multiple point histograms, linear functions and two point cluster functions. The descriptor testing consists of stochastically generating realizations from a reference image using the simulated annealing optimization procedure introduced by Karsanina et al. (2015). This procedure basically minimizes the differences between pre-specified descriptor values associated with the training image and the image being produced. The most efficient descriptor set can therefore be identified by comparing the image generation quality among the tested descriptor combinations. The assessment

  20. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1999-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...

  1. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2002-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...

  2. Gravitational self-organizing map-based seismic image classification with an adaptive spectral-textural descriptor

    Science.gov (United States)

    Hao, Yanling; Sun, Genyun

    2016-10-01

    Seismic image classification is of vital importance for extracting damage information and evaluating disaster losses. With the increasing availability of high resolution remote sensing images, automatic image classification offers a unique opportunity to accommodate the rapid damage mapping requirements. However, the diversity of disaster types and the lack of uniform statistical characteristics in seismic images increase the complexity of automated image classification. This paper presents a novel automatic seismic image classification approach by integrating an adaptive spectral-textural descriptor into gravitational self-organizing map (gSOM). In this approach, seismic image is first segmented into several objects based on mean shift (MS) method. These objects are then characterized explicitly by spectral and textural feature quantization histograms. To objectify the image object delineation adapt to various disaster types, an adaptive spectral-textural descriptor is developed by integrating the histograms automatically. Subsequently, these objects as classification units are represented by neurons in a self-organizing map and clustered by adjacency gravitation. By moving the neurons around the gravitational space and merging them according to the gravitation, the object-based gSOM is able to find arbitrary shape and determine the class number automatically. Taking advantage of the diversity of gSOM results, consensus function is then conducted to discover the most suitable classification result. To confirm the validity of the presented approach, three aerial seismic images in Wenchuan covering several disaster types are utilized. The obtained quantitative and qualitative experimental results demonstrated the feasibility and accuracy of the proposed seismic image classification method.

  3. Quantum chemical topology (QCT) descriptors as substitutes for appropriate Hammett constants.

    Science.gov (United States)

    Smith, P J; Popelier, P L A

    2005-09-21

    A technique called quantum topological molecular similarity (QTMS) was recently proposed [J. Chem. Inf. Comput. Sci., 2001, 41, 764] in order to construct a variety of medicinal, ecological and physical organic QSAR/QSPRs, based on modern ab initio wave functions of geometry optimised molecules, in combination with quantum chemical topology (QCT). The current abundance of computing power can be utilised to inject realistic descriptors into QSAR/QSPRs. In previous work [J. Chem. Soc., Perkin Trans. 2, 2002, 1231] it was proven that a set of Hammett constants (sigma(p), sigma(m), sigma(I) and sigma(p)0) for a sizeable set of mono- and polysubstituted carboxylic acids can be replaced by QCT bond descriptors. Using QTMS and proper statistical validation we examined seven data sets in total. The first three sets (para-substituted phenols (sigma-), substituted toluenes (sigma+) and bromophenethylamines (sigma+)) corroborate that a wider class of Hammett constants can also be replaced by QCT descriptors. A fourth set (benzyl radicals) focuses on non-Hammett behaviour being superimposed on Hammett behaviour. QCT descriptors selectively correlate with Hammett behaviour. The QTMS analysis of the last three sets (toxicity of benzyl alcohols, chromatographic capacity factors of chalcones and herbicidal activity of 5-chloro-2,3-dicyanopyrazines) screens for false positives. This test is successfully passed in that QCT descriptors fail when lipophilicity/hydrophobicity is in charge. Hence, overall, the discriminatory capacity of QCT descriptors is established, in detecting Hammett behaviour and specifically replacing the Hammett constants by more modern and non-empirical descriptors.

  4. Relationship between Dyspnea Descriptors and Underlying Causes of the Symptom; a Cross-sectional Study.

    Science.gov (United States)

    Sajadi, Seyyed Mohammad Ali; Majidi, Alireza; Abdollahimajd, Fahimeh; Jalali, Fatemeh

    2017-01-01

    History taking and physical examination help clinicians identify the patient's problem and effectively treat it. This study aimed to evaluate the descriptors of dyspnea in patients presenting to emergency department (ED) with asthma, congestive heart failure (CHF), and chronic obstructive pulmonary disease (COPD). This cross-sectional study was conducted on all patients presenting to ED with chief complaint of dyspnea, during 2 years. The patients were asked to describe their dyspnea by choosing three items from the valid and reliable questionnaire or articulating their sensation. The relationship between dyspnea descriptors and underlying cause of symptom was evaluated using SPSS version 16. 312 patients with the mean age of 60.96±17.01 years were evaluated (53.2% male). Most of the patients were > 65 years old (48.7%) and had basic level of education (76.9%). "My breath doesn't go out all the way" with 83.1%, "My chest feels tight " with 45.8%, and "I feel that my airway is obstructed" with 40.7%, were the most frequent dyspnea descriptors in asthma patients. "My breathing requires work" with 46.3%, "I feel that I am suffocating" with 31.5%, and "My breath doesn't go out all the way" with 29.6%, were the most frequent dyspnea descriptors in COPD patients. "My breathing is heavy" with 74.4%, "A hunger for more air" with 24.4%, and "I cannot get enough air" with 23.2%, were the most frequent dyspnea descriptors in CHF patients. Except for "My breath does not go in all the way", there was significant correlation between studied dyspnea descriptors and underlying disease (p = 0.001 for all analyses). It seems that dyspnea descriptors along with other findings from history and physical examination could be helpful in differentiating the causes of the symptom in patients presenting to ED suffering from dyspnea.

  5. Landfill Top Covers

    DEFF Research Database (Denmark)

    Scheutz, Charlotte; Kjeldsen, Peter

    2011-01-01

    the landfill section has been filled or several years later depending on the settlement patterns. Significant differential settlements may disturb the functioning of the top cover. The specific design of the cover system depends on the type of waste landfilled (municipal, hazardous, or inert waste...... such as lowpermeability clay soils and geomembranes are required. The avoidance of water input to organic waste may impede the microbial stabilization processes including gas generation. Therefore watertight top covers may be in conflict with the purposes of reactor landfills (see Chapter 10.6). At some sites covers...... sometimes are made to include components for recirculation of landfill leachate (see Section 10.9.2 for more details). The top cover is an important factor in the water management of landfills. Details about water infiltration through top covers and its influence on the hydrology of the landfill is covered...

  6. Cross recurrence quantification for cover song identification

    Energy Technology Data Exchange (ETDEWEB)

    Serra, Joan; Serra, Xavier; Andrzejak, Ralph G [Department of Information and Communication Technologies, Universitat Pompeu Fabra, Roc Boronat 138, 08018 Barcelona (Spain)], E-mail: joan.serraj@upf.edu

    2009-09-15

    There is growing evidence that nonlinear time series analysis techniques can be used to successfully characterize, classify, or process signals derived from real-world dynamics even though these are not necessarily deterministic and stationary. In the present study, we proceed in this direction by addressing an important problem our modern society is facing, the automatic classification of digital information. In particular, we address the automatic identification of cover songs, i.e. alternative renditions of a previously recorded musical piece. For this purpose, we here propose a recurrence quantification analysis measure that allows the tracking of potentially curved and disrupted traces in cross recurrence plots (CRPs). We apply this measure to CRPs constructed from the state space representation of musical descriptor time series extracted from the raw audio signal. We show that our method identifies cover songs with a higher accuracy as compared to previously published techniques. Beyond the particular application proposed here, we discuss how our approach can be useful for the characterization of a variety of signals from different scientific disciplines. We study coupled Roessler dynamics with stochastically modulated mean frequencies as one concrete example to illustrate this point.

  7. Content-Based Image Retrieval using Local Features Descriptors and Bag-of-Visual Words

    Directory of Open Access Journals (Sweden)

    Mohammed Alkhawlani

    2015-09-01

    Full Text Available Image retrieval is still an active research topic in the computer vision field. There are existing several techniques to retrieve visual data from large databases. Bag-of-Visual Word (BoVW is a visual feature descriptor that can be used successfully in Content-based Image Retrieval (CBIR applications. In this paper, we present an image retrieval system that uses local feature descriptors and BoVW model to retrieve efficiently and accurately similar images from standard databases. The proposed system uses SIFT and SURF techniques as local descriptors to produce image signatures that are invariant to rotation and scale. As well as, it uses K-Means as a clustering algorithm to build visual vocabulary for the features descriptors that obtained of local descriptors techniques. To efficiently retrieve much more images relevant to the query, SVM algorithm is used. The performance of the proposed system is evaluated by calculating both precision and recall. The experimental results reveal that this system performs well on two different standard datasets.

  8. An Effective 3D Shape Descriptor for Object Recognition with RGB-D Sensors

    Directory of Open Access Journals (Sweden)

    Zhong Liu

    2017-02-01

    Full Text Available RGB-D sensors have been widely used in various areas of computer vision and graphics. A good descriptor will effectively improve the performance of operation. This article further analyzes the recognition performance of shape features extracted from multi-modality source data using RGB-D sensors. A hybrid shape descriptor is proposed as a representation of objects for recognition. We first extracted five 2D shape features from contour-based images and five 3D shape features over point cloud data to capture the global and local shape characteristics of an object. The recognition performance was tested for category recognition and instance recognition. Experimental results show that the proposed shape descriptor outperforms several common global-to-global shape descriptors and is comparable to some partial-to-global shape descriptors that achieved the best accuracies in category and instance recognition. Contribution of partial features and computational complexity were also analyzed. The results indicate that the proposed shape features are strong cues for object recognition and can be combined with other features to boost accuracy.

  9. Prediction of olive oil sensory descriptors using instrumental data fusion and partial least squares (PLS) regression.

    Science.gov (United States)

    Borràs, Eva; Ferré, Joan; Boqué, Ricard; Mestres, Montserrat; Aceña, Laura; Calvo, Angels; Busto, Olga

    2016-08-01

    Headspace-Mass Spectrometry (HS-MS), Fourier Transform Mid-Infrared spectroscopy (FT-MIR) and UV-Visible spectrophotometry (UV-vis) instrumental responses have been combined to predict virgin olive oil sensory descriptors. 343 olive oil samples analyzed during four consecutive harvests (2010-2014) were used to build multivariate calibration models using partial least squares (PLS) regression. The reference values of the sensory attributes were provided by expert assessors from an official taste panel. The instrumental data were modeled individually and also using data fusion approaches. The use of fused data with both low- and mid-level of abstraction improved PLS predictions for all the olive oil descriptors. The best PLS models were obtained for two positive attributes (fruity and bitter) and two defective descriptors (fusty and musty), all of them using data fusion of MS and MIR spectral fingerprints. Although good predictions were not obtained for some sensory descriptors, the results are encouraging, specially considering that the legal categorization of virgin olive oils only requires the determination of fruity and defective descriptors.

  10. On application of constitutional descriptors for merging of quinoxaline data sets using linear statistical methods.

    Science.gov (United States)

    Ghosh, Payel; Vracko, Marjan; Chattopadhyay, Asis Kumar; Bagchi, Manish C

    2008-08-01

    The present paper is an attempt for unifying two different quinoxaline data sets with a wide range of substituents in 2, 3, 7, and 8 positions having excellent antitubercular activities with a view to developing robust and reliable structure-activity relationships. The merging has been performed for these two sets of quinoxaline 1,4-di-N-oxides derivatives comprising 29 and 18 compounds, respectively, on the basis of constitutional descriptors, which denotes the structural characterization of the molecules. Principal component analysis was performed to see the distribution of the compounds from two data sets for the constitutional descriptors. The distribution of compounds in score plot based on constitutional descriptors suggests unification of quinoxaline data sets which is useful for the model development. Outlier detection was performed from the standpoint of residual analysis of the partial least squares regression models. The superiority of the constitutional descriptors over other calculated molecular descriptors has been established from the standpoint of leave-one-out cross-validation technique associated with partial least squares regression analysis. Internal validation through the leave-many-out methodology was also performed with good results, assuring the stability of the models. The results obtained from linear partial least squares regression analysis lead to a statistically significant and robust quantitative structure-activity relationship modeling.

  11. Thesaurus of descriptors for the vertical file system

    Energy Technology Data Exchange (ETDEWEB)

    1977-09-01

    The Thesaurus used for the NYIT Energy Information Center is presented. The center is a comprehensive information service covering every aspect of energy conservation and related technology, including conservation programs and practices, alternative energy systems, energy legislation, and public policy development in the United States and abroad. The Thesaurus includes all subject headings found in the Vertical File as well as other cross referenced terms likely to come to mind when seeking information on a specific energy area.

  12. Landfill Top Covers

    DEFF Research Database (Denmark)

    Scheutz, Charlotte; Kjeldsen, Peter

    2011-01-01

    is landscaped in order to fit into the surrounding area/environment or meet specific plans for the final use of the landfill. To fulfill the above listed requirements landfill covers are often multicomponent systems which are placed directly on top of the waste. The top cover may be placed immediately after...... the landfill section has been filled or several years later depending on the settlement patterns. Significant differential settlements may disturb the functioning of the top cover. The specific design of the cover system depends on the type of waste landfilled (municipal, hazardous, or inert waste...... however, top covers may be the only environmental protection measure. In some landfill regulations (for instance the Subtitle D landfills receiving municipal solid waste in the USA) it is required to minimize infiltration into the waste layers. Therefore top covers containing liner components...

  13. Ant colony optimization as a descriptor selection in QSPR modeling for prediction of λmax of azo dyes

    Institute of Scientific and Technical Information of China (English)

    Morteza Atabati; Farzaneh Khandani

    2012-01-01

    A quantitative structure-property relationship (QSPR) study was suggested for the prediction of λmax of azo dyes.After optimization of 3D geometry of structures,different descriptors were calculated by the HyperChem and Dragon softwares.A major problem of QSPR is the high dimensionality of the descriptor space; therefore,descriptor selection is the most important step for these studies.In this paper,an ant colony optimization (ACO) algorithm was proposed to select the best descriptors.

  14. Percent Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High percentages of forest cover (FORPCT) generally indicate healthier ecosystems and cleaner surface water. More...

  15. Saturated Domino Coverings

    CERN Document Server

    Buchanan, Andrew; Ryba, Alex

    2011-01-01

    A domino covering of a board is saturated if no domino is redundant. We introduce the concept of a fragment tiling and show that a minimal fragment tiling always corresponds to a maximal saturated domino covering. The size of a minimal fragment tiling is the domination number of the board. We define a class of regular boards and show that for these boards the domination number gives the size of a minimal X-pentomino covering. Natural sequences that count maximal saturated domino coverings of square and rectangular boards are obtained. These include the new sequences A193764, A193765, A193766, A193767, and A193768 of OEIS.

  16. Percent Forest Cover (Future)

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High percentages of forest cover (FORPCTFuture) generally indicate healthier ecosystems and cleaner surface water....

  17. Image characterization by fractal descriptors in variational mode decomposition domain: Application to brain magnetic resonance

    Science.gov (United States)

    Lahmiri, Salim

    2016-08-01

    The main purpose of this work is to explore the usefulness of fractal descriptors estimated in multi-resolution domains to characterize biomedical digital image texture. In this regard, three multi-resolution techniques are considered: the well-known discrete wavelet transform (DWT) and the empirical mode decomposition (EMD), and; the newly introduced; variational mode decomposition mode (VMD). The original image is decomposed by the DWT, EMD, and VMD into different scales. Then, Fourier spectrum based fractal descriptors is estimated at specific scales and directions to characterize the image. The support vector machine (SVM) was used to perform supervised classification. The empirical study was applied to the problem of distinguishing between normal and abnormal brain magnetic resonance images (MRI) affected with Alzheimer disease (AD). Our results demonstrate that fractal descriptors estimated in VMD domain outperform those estimated in DWT and EMD domains; and also those directly estimated from the original image.

  18. Audio Environment Recognition using Zero Crossing Features and MPEG-7 Descriptors

    Directory of Open Access Journals (Sweden)

    Saleh Al-Zhrani

    2010-01-01

    Full Text Available Problem statement: This study investigated zero crossing features and selected MPEG-7 audio descriptors for environment sound recognition applications such as audio forensics. Approach: The study implemented several experiments focusing on the problems of environment recognition from audio particularly for forensic applications. Results: It was investigated the effect of the temporal zero crossing feature as well as selected MPEG-7 audio low level descriptors on environment sound recognition. The performance was evaluated against a varying number of training sounds and samples per training file. Conclusion/Recommendations: Experimental results showed that higher recognition accuracy is achieved by increasing the number of training files and by decreasing the number of samples per training file. This study presented an audio environment recognition using zero crossing features and MPEG-7 Descriptors.

  19. A descriptor of amino acids: SVRG and its application to peptide quantitative structure-activity relationship.

    Science.gov (United States)

    Tong, J; Che, T; Li, Y; Wang, P; Xu, X; Chen, Y

    2011-01-01

    In this work, a descriptor, SVRG (principal component scores vector of radial distribution function descriptors and geometrical descriptors), was derived from principal component analysis (PCA) of a matrix of two structural variables of coded amino acids, including radial distribution function index (RDF) and geometrical index. SVRG scales were then applied in three panels of peptide quantitative structure-activity relationships (QSARs) which were modelled by partial least squares regression (PLS). The obtained models with the correlation coefficient (R²(cum)), cross-validation correlation coefficient (Q²(LOO)) were 0.910 and 0.863 for 48 bitter-tasting dipeptides; 0.968 and 0.931 for 21 oxytocin analogues; and 0.992 and 0.954 for 20 thromboplastin inhibitors. Satisfactory results showed that SVRG contained much chemical information relating to bioactivities. The approach may be a useful structural expression methodology for studies on peptide QSAR.

  20. Response to: "Limitations of the Method of Lagrangian Descriptors" [arXiv:1510.04838

    CERN Document Server

    Balibrea-Iniesta, F; García-Garrido, V J; Lopesino, C; Mancho, A M; Mendoza, C; Wiggins, S

    2016-01-01

    This Response is concerned with the recent Comment of Ruiz-Herrera, "Limitations of the Method of Lagrangian Descriptors" [arXiv:1510.04838], criticising the method of Lagrangian Descriptors. In spite of the significant body of literature asserting the contrary, Ruiz-Herrera claims that the method fails to reveal the presence of stable and unstable manifolds of hyperbolic trajectories in incompressible systems and in almost all linear systems. He supports this claim by considering the method of Lagrangian descriptors applied to three specific examples. However in this response we show that Ruiz-Herrera does not understand the proper application and interpretation of the method and, when correctly applied, the method beautifully and unambiguously detects the stable and unstable manifolds of the hyperbolic trajectories in his examples.

  1. Genetic divergence among Brazilian turmeric germplasm using morpho-agronomical descriptors

    Directory of Open Access Journals (Sweden)

    Mário Sérgio Sigrist

    2011-01-01

    Full Text Available Turmeric (Curcuma longa L. is a vegetatively-propagated crop which is used as a natural dye in the food industryand also presents many biological active compounds. Turmeric conventional breeding is difficult and often limited to germplasmselection. The aim of this study was to evaluate the genetic divergence among turmeric accessions available in Brazil using sevenmorpho-agronomical descriptors. Overall genetic divergence was low, although some divergent genotypes were identified. Fourmain groups of genotypes were identified and could be further used in breeding programs. Canonical variable analysis suggestedthat some descriptors were more important to discriminate accessions and also that one of the descriptors could be discarded. Theresults provided useful insights for better management of the germplasm collection, optimizing conservational and breeding efforts.

  2. RESEARCH ON FEATURE POINTS EXTRACTION METHOD FOR BINARY MULTISCALE AND ROTATION INVARIANT LOCAL FEATURE DESCRIPTOR

    Directory of Open Access Journals (Sweden)

    Hongwei Ying

    2014-08-01

    Full Text Available An extreme point of scale space extraction method for binary multiscale and rotation invariant local feature descriptor is studied in this paper in order to obtain a robust and fast method for local image feature descriptor. Classic local feature description algorithms often select neighborhood information of feature points which are extremes of image scale space, obtained by constructing the image pyramid using certain signal transform method. But build the image pyramid always consumes a large amount of computing and storage resources, is not conducive to the actual applications development. This paper presents a dual multiscale FAST algorithm, it does not need to build the image pyramid, but can extract feature points of scale extreme quickly. Feature points extracted by proposed method have the characteristic of multiscale and rotation Invariant and are fit to construct the local feature descriptor.

  3. Specific stability region analysis for uncertain fuzzy descriptor systems with multiple derivative matrices

    Science.gov (United States)

    Huang, Chih-Peng

    2016-06-01

    This paper addresses the specific stability region for uncertain fuzzy descriptor systems with distinct derivative matrices in the rules. First, an equivalent poles' location criterion for the nominal descriptor system is originally derived and expressed as one compact form of strict and complex linear matrix inequality (LMI). Then, the result can be extended to cope with the specific stability region for the uncertain fuzzy descriptor systems with integrating multiple derivative matrices. Moreover, since the presented criteria involve complex LMIs, we appropriately conduct a projection scheme, where current LMI tools cannot evaluate them. By deriving useful projection operators onto the formed convex sets, an analysing algorithm is consequently presented for numerical evaluation. Finally, three numerical examples, two nonlinear systems and a physical circuit system, are given to demonstrate the validity and the practicability of the proposed approach.

  4. Application of the quantum mechanical IEF/PCM-MST hydrophobic descriptors to selectivity in ligand binding.

    Science.gov (United States)

    Ginex, Tiziana; Muñoz-Muriedas, Jordi; Herrero, Enric; Gibert, Enric; Cozzini, Pietro; Luque, F Javier

    2016-06-01

    We have recently reported the development and validation of quantum mechanical (QM)-based hydrophobic descriptors derived from the parametrized IEF/PCM-MST continuum solvation model for 3D-QSAR studies within the framework of the Hydrophobic Pharmacophore (HyPhar) method. In this study we explore the applicability of these descriptors to the analysis of selectivity fields. To this end, we have examined a series of 88 compounds with inhibitory activities against thrombin, trypsin and factor Xa, and the HyPhar results have been compared with 3D-QSAR models reported in the literature. The quantitative models obtained by combining the electrostatic and non-electrostatic components of the octanol/water partition coefficient yield results that compare well with the predictive potential of standard CoMFA and CoMSIA techniques. The results also highlight the potential of HyPhar descriptors to discriminate the selectivity of the compounds against thrombin, trypsin, and factor Xa. Moreover, the graphical representation of the hydrophobic maps provides a direct linkage with the pattern of interactions found in crystallographic structures. Overall, the results support the usefulness of the QM/MST-based hydrophobic descriptors as a complementary approach for disclosing structure-activity relationships in drug design and for gaining insight into the molecular determinants of ligand selectivity. Graphical Abstract Quantum Mechanical continuum solvation calculations performed with the IEF/PCM-MST method are used to derived atomic hydrophobic descriptors, which are then used to discriminate the selectivity of ligands against thrombin, trypsin and factor Xa. The descriptors provide complementary view to standard 3D-QSAR analysis, leading to a more comprehensive understanding of ligand recognition.

  5. Graph of atomic orbitals and the molecular structure-descriptors based on it

    Directory of Open Access Journals (Sweden)

    ANDREY A. TOROPOV

    2005-04-01

    Full Text Available The graph of atomic orbitals (GAO is a novel type of molecular graph, recently proposed by one of the authors. Various molecular structure-descriptors computed for GAO are compared with their analogs computed for ordinary molecular graphs. The quality of these structure-descriptors was tested for correlation with the normal boiling points of alkanes and cycloalkanes. In all the studied cases, the results based on GAO are similar to, and usually slightly better than, those obtained by means of ordinary molecular graps.

  6. Application of descriptor approaches in design of PD observer-based actuator fault estimation

    Directory of Open Access Journals (Sweden)

    Filasová Anna

    2015-03-01

    Full Text Available Stability analysis and design for continuous-time proportional plus derivative state observers is presented in the paper with the goal to establish the system state and actuator fault estimation. Design problem accounts a descriptor principle formulation for non-descriptor systems, guaranteing asymptotic convergence both the state observer error as fault estimate error. Presented in the sense of the second Lyapunov method, an associated structure of linear matrix inequalities is outlined to possess parameter existence of the proposed estimator structure. The obtained design conditions are verified by simulation using a numerical illustrative example.

  7. An explicit approach to conceptual density functional theory descriptors of arbitrary order

    Science.gov (United States)

    Heidar-Zadeh, Farnaz; Richer, Michael; Fias, Stijn; Miranda-Quintana, Ramón Alain; Chan, Matthew; Franco-Pérez, Marco; González-Espinoza, Cristina E.; Kim, Taewon David; Lanssens, Caitlin; Patel, Anand H. G.; Yang, Xiaotian Derrick; Vöhringer-Martinez, Esteban; Cárdenas, Carlos; Verstraelen, Toon; Ayers, Paul W.

    2016-09-01

    We present explicit formulas for arbitrary-order derivatives of the energy, grand potential, electron density, and higher-order response functions with respect to the number of electrons, and the chemical potential for any smooth and differentiable model of the energy versus the number of electrons. The resulting expressions for global reactivity descriptors (hyperhardnesses and hypersoftnesses), local reactivity descriptors (hyperFukui functions and local hypersoftnesses), and nonlocal response functions are easy to evaluate computationally. Specifically, the explicit formulas for global/local/nonlocal hypersoftnesses of arbitrary order are derived using Bell polynomials. Explicit expressions for global and local hypersoftness indicators up to fifth order are presented.

  8. Structure-Activity Relationships on the Molecular Descriptors Family Project at the End

    Directory of Open Access Journals (Sweden)

    Lorentz JÄNTSCHI

    2007-12-01

    Full Text Available Molecular Descriptors Family (MDF on the Structure-Activity Relationships (SAR, a promising approach in investigation and quantification of the link between 2D and 3D structural information and the activity, and its potential in the analysis of the biological active compounds is summarized. The approach, attempts to correlate molecular descriptors family generated and calculated on a set of biological active compounds with their observed activity. The estimation as well as prediction abilities of the approach are presented. The obtained MDF SAR models can be used to predict the biological activity of unknown substrates in a series of compounds.

  9. Complex Correlation Measure: a novel descriptor for Poincaré plot

    Directory of Open Access Journals (Sweden)

    Gubbi Jayavardhana

    2009-08-01

    Full Text Available Abstract Background Poincaré plot is one of the important techniques used for visually representing the heart rate variability. It is valuable due to its ability to display nonlinear aspects of the data sequence. However, the problem lies in capturing temporal information of the plot quantitatively. The standard descriptors used in quantifying the Poincaré plot (SD1, SD2 measure the gross variability of the time series data. Determination of advanced methods for capturing temporal properties pose a significant challenge. In this paper, we propose a novel descriptor "Complex Correlation Measure (CCM" to quantify the temporal aspect of the Poincaré plot. In contrast to SD1 and SD2, the CCM incorporates point-to-point variation of the signal. Methods First, we have derived expressions for CCM. Then the sensitivity of descriptors has been shown by measuring all descriptors before and after surrogation of the signal. For each case study, lag-1 Poincaré plots were constructed for three groups of subjects (Arrhythmia, Congestive Heart Failure (CHF and those with Normal Sinus Rhythm (NSR, and the new measure CCM was computed along with SD1 and SD2. ANOVA analysis distribution was used to define the level of significance of mean and variance of SD1, SD2 and CCM for different groups of subjects. Results CCM is defined based on the autocorrelation at different lags of the time series, hence giving an in depth measurement of the correlation structure of the Poincaré plot. A surrogate analysis was performed, and the sensitivity of the proposed descriptor was found to be higher as compared to the standard descriptors. Two case studies were conducted for recognizing arrhythmia and congestive heart failure (CHF subjects from those with NSR, using the Physionet database and demonstrated the usefulness of the proposed descriptors in biomedical applications. CCM was found to be a more significant (p = 6.28E-18 parameter than SD1 and SD2 in discriminating

  10. Nonlinear Adaptive Descriptor Observer for the Joint States and Parameters Estimation

    KAUST Repository

    2016-08-29

    In this note, the joint state and parameters estimation problem for nonlinear multi-input multi-output descriptor systems is considered. Asymptotic convergence of the adaptive descriptor observer is established by a sufficient set of linear matrix inequalities for the noise-free systems. The noise corrupted systems are also considered and it is shown that the state and parameters estimation errors are bounded for bounded noises. In addition, if the noises are bounded and have zero mean, then the estimation errors asymptotically converge to zero in the mean. The performance of the proposed adaptive observer is illustrated by a numerical example.

  11. Joint efforts to harmonize sound insulation descriptors and classification schemes in Europe (COST TU0901)

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    2010-01-01

    Sound insulation descriptors, regulatory requirements and classification schemes in Europe represent a high degree of diversity. One implication is very little exchange of experience of housing design and construction details for different levels of sound insulation; another is trade barriers...... Aspects in Sustainable Urban Housing Constructions", has been approved and runs 2009-2013. The main objectives are to prepare proposals for harmonized sound insulation descriptors and for a European sound classification scheme. Other goals are e.g. to establish a catalogue of sound insulation data...

  12. CALCULATION OF COEFFICIENT OF SHARING OCTANOL-WATER OF ORGANIC COMPOUNDS USING MOLECULAR DESCRIPTORS

    Directory of Open Access Journals (Sweden)

    B. Souyei

    2010-12-01

    Full Text Available A quantitative structure-property relationship (QSPR study is carried out to develop correlations that relate the molecular structures of organic compounds to their Octanol- Water partition coefficients, Kow , using molecular descriptors. The correlations are simple in application with good accuracy, which provide an easy, direct and relatively accurate way to calculate Kow. Such calculation gives us a model that gives results in remarkable correlation with the descriptors of blocks fragments of the atom-centered and functional groups (R2 = 0.949, δ = 0477 (R2 = 0.926,δ = 0,548 respectively.

  13. Robust H∞ control for uncertain descriptor systems with state and control delay

    Institute of Scientific and Technical Information of China (English)

    Piao Fengxian; Zhang Qingling; Ma Xiuzhen

    2006-01-01

    The problem of robust stabilization for uncertain continuous descriptor system with state and control delay is considered. The time-varying parametric uncertainty is assumed to be norm-bounded. The purpose of the robust stabilization is to design a memoryless state feedback law such that the resulting closed-loop system is robustly stable. A sufficient condition that uncertain continuous descriptor system is robustly stabilizabled by state feedback law is derived in terms of linear matrix inequality (LMI). Finally, a numerical example is provided to demonstrate the application of the proposed method.

  14. Land Cover Characterization Program

    Science.gov (United States)

    ,

    1997-01-01

    The U.S. Geological Survey (USGS) has a long heritage of leadership and innovation in land use and land cover mapping. The USGS Anderson system defined the principles for land use and land cover mapping that have been the model both nationally and internationally for more than 20 years. The Land Cover Characterization Program (LCCP) is founded on the premise that the Nation's needs for land cover and land use data are diverse and increasingly sophisticated. The range of projects, programs, and organizations that use land cover data to meet their planning, management, development, and assessment objectives has expanded significantly. The reasons for this are numerous, and include the improved capabilities provided by geographic information systems, better and more data-intensive analytic models, and increasing requirements for improved information for decision making. The overall goals of the LCCP are to:

  15. Land Cover Trends Project

    Science.gov (United States)

    Acevedo, William

    2006-01-01

    The Land Cover Trends Project is designed to document the types, rates, causes, and consequences of land cover change from 1973 to 2000 within each of the 84 U.S. Environmental Protection Agency (EPA) Level III ecoregions that span the conterminous United States. The project's objectives are to: * Develop a comprehensive methodology using probability sampling and change analysis techniques and Landsat Multispectral Scanner (MSS), Thematic Mapper (TM), and Enhanced Thematic Mapper (ETM) data for estimating regional land cover change. * Characterize the spatial and temporal characteristics of conterminous U.S. land cover change for five periods from 1973 to 2000 (nominally 1973, 1980, 1986, 1992, and 2000). * Document the regional driving forces and consequences of change. * Prepare a national synthesis of land cover change.

  16. Flat covers of modules

    CERN Document Server

    Xu, Jinzhong

    1996-01-01

    Since the injective envelope and projective cover were defined by Eckmann and Bas in the 1960s, they have had great influence on the development of homological algebra, ring theory and module theory. In the 1980s, Enochs introduced the flat cover and conjectured that every module has such a cover over any ring. This book provides the uniform methods and systematic treatment to study general envelopes and covers with the emphasis on the existence of flat cover. It shows that Enochs' conjecture is true for a large variety of interesting rings, and then presents the applications of the results. Readers with reasonable knowledge in rings and modules will not have difficulty in reading this book. It is suitable as a reference book and textbook for researchers and graduate students who have an interest in this field.

  17. In vivo study of the wear of a reinforced composite used to cover implant-supported frameworks.

    Science.gov (United States)

    David, Susana; Del Rio, Jaime; Celemín, Alicia; Serrano, Carlos

    2009-01-01

    The goal of this study was to research the wear shown by a material (Cristobal+) offered as an alternative to ceramics in the covering of an implant-supported fixed prosthesis. Twenty-six active cusps were used in this study; the control group consisted of 12 cusps adjacent to restorations composed of Cristobal+. Five images were obtained from each sample and analyzed using computer software that creates an arch along each cusp, so each image gives the value of the radius described by that arch. If a sample showed any sign of wear, the values for the successive radii would be increasingly larger since a flattened arch would produce a larger radius. An analysis of the paired Student t test was applied. After assessing the results, a statistically significant difference in wear was noted (P Cristobal+ reinforced composite was greater than that of the natural adjacent cusps.

  18. Covering folded shapes

    Directory of Open Access Journals (Sweden)

    Oswin Aichholzer

    2014-05-01

    Full Text Available Can folding a piece of paper flat make it larger? We explore whether a shape S must be scaled to cover a flat-folded copy of itself. We consider both single folds and arbitrary folds (continuous piecewise isometries \\(S\\to\\mathbb{R}^2\\. The underlying problem is motivated by computational origami, and is related to other covering and fixturing problems, such as Lebesgue's universal cover problem and force closure grasps. In addition to considering special shapes (squares, equilateral triangles, polygons and disks, we give upper and lower bounds on scale factors for single folds of convex objects and arbitrary folds of simply connected objects.

  19. Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images.

    Science.gov (United States)

    Barisoni, Laura; Troost, Jonathan P; Nast, Cynthia; Bagnasco, Serena; Avila-Casado, Carmen; Hodgin, Jeffrey; Palmer, Matthew; Rosenberg, Avi; Gasim, Adil; Liensziewski, Chrysta; Merlino, Lino; Chien, Hui-Ping; Chang, Anthony; Meehan, Shane M; Gaut, Joseph; Song, Peter; Holzman, Lawrence; Gibson, Debbie; Kretzler, Matthias; Gillespie, Brenda W; Hewitt, Stephen M

    2016-07-01

    The multicenter Nephrotic Syndrome Study Network (NEPTUNE) digital pathology scoring system employs a novel and comprehensive methodology to document pathologic features from whole-slide images, immunofluorescence and ultrastructural digital images. To estimate inter- and intra-reader concordance of this descriptor-based approach, data from 12 pathologists (eight NEPTUNE and four non-NEPTUNE) with experience from training to 30 years were collected. A descriptor reference manual was generated and a webinar-based protocol for consensus/cross-training implemented. Intra-reader concordance for 51 glomerular descriptors was evaluated on jpeg images by seven NEPTUNE pathologists scoring 131 glomeruli three times (Tests I, II, and III), each test following a consensus webinar review. Inter-reader concordance of glomerular descriptors was evaluated in 315 glomeruli by all pathologists; interstitial fibrosis and tubular atrophy (244 cases, whole-slide images) and four ultrastructural podocyte descriptors (178 cases, jpeg images) were evaluated once by six and five pathologists, respectively. Cohen's kappa for inter-reader concordance for 48/51 glomerular descriptors with sufficient observations was moderate (0.40transformation. NEPTUNE digital pathology scoring system enables novel morphologic profiling of renal structures. For all histologic and ultrastructural descriptors tested with sufficient observations, moderate-to-excellent concordance was seen for 31/54 (57%). Descriptors not sufficiently represented will require further testing. This study proffers the NEPTUNE digital pathology scoring system as a model for standardization of renal biopsy interpretation extendable outside the NEPTUNE consortium, enabling international collaborations.

  20. IN SILICO EVALUATION OF ANGIOTENSIN II RECEPTOR ANTAGONIST’S PLASMA PROTEIN BINDING USING COMPUTED MOLECULAR DESCRIPTORS

    Directory of Open Access Journals (Sweden)

    Jadranka Odović

    2014-03-01

    Full Text Available The discovery of new pharmacologically active substances and drugs modeling led to necessity of predicting drugs properties and its ADME data. Angiotensin II receptor antagonists are a group of pharmaceuticals which modulate the renin-angiotensin-aldosterone system and today represent the most commonly prescribed anti-hypertensive drugs. The aim of this study was to compare different molecular properties of seven angiotensin II receptor antagonists / blockers (ARBs, (eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan and their plasma protein binding (PPB data. Several ARBs molecular descriptors were calculated using software package Molinspiration Depiction Software as well as Virtual Computational Chemistry Laboratory (electronic descriptor – PSA, constitutional parameter – Mw, geometric descriptor – Vol, lipophilicity descriptors - logP values, aqueous solubility data – logS. The correlations between all collected descriptors and plasma protein binding data obtained from relevant literature were established. In the simple linear regression poor correlations were obtained in relationships between PPB data and all calculated molecular descriptors. In the next stage of the study multiple linear regression (MLR was used for correlation of PPB data with two different descriptors as independent variables. The best correlation (R2=0.70 with P<0.05 was established between PPB data and molecular weight with addition of volume values as independent variables. The possible application of computed molecular descriptors in drugs protein binding evaluation can be of great importance in drug research.

  1. Design and evaluation of a molecular fingerprint involving the transformation of property descriptor values into a binary classification scheme.

    Science.gov (United States)

    Xue, Ling; Godden, Jeffrey W; Stahura, Florence L; Bajorath, Jürgen

    2003-01-01

    A new fingerprint design concept is introduced that transforms molecular property descriptors into two-state descriptors and thus permits binary encoding. This transformation is based on the calculation of statistical medians of descriptor distributions in large compound collections and alleviates the need for value range encoding of these descriptors. For binary encoded property descriptors, bit positions that are set off capture as much information as bit positions that are set on, different from conventional fingerprint representations. Accordingly, a variant of the Tanimoto coefficient has been defined for comparison of these fingerprints. Following our design idea, a prototypic fingerprint termed MP-MFP was implemented by combining 61 binary encoded property descriptors with 110 structural fragment-type descriptors. The performance of this fingerprint was evaluated in systematic similarity search calculations in a database containing 549 molecules belonging to 38 different activity classes and 5000 background molecules. In these calculations, MP-MFP correctly recognized approximately 34% of all similarity relationships, with only 0.04% false positives, and performed better than previous designs and MACCS keys. The results suggest that combinations of simplified two-state property descriptors have predictive value in the analysis of molecular similarity.

  2. Percent Wetland Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — Wetlands act as filters, removing or diminishing the amount of pollutants that enter surface water. Higher values for percent of wetland cover (WETLNDSPCT) may be...

  3. Percent of Impervious Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — High amounts of impervious cover (parking lots, rooftops, roads, etc.) can increase water runoff, which may directly enter surface water. Runoff from roads often...

  4. Percent Wetland Cover (Future)

    Data.gov (United States)

    U.S. Environmental Protection Agency — Wetlands act as filters, removing or diminishing the amount of pollutants that enter surface water. Higher values for percent of wetland cover (WETLNDSPCT) may be...

  5. GAP Land Cover - Image

    Data.gov (United States)

    Minnesota Department of Natural Resources — This raster dataset is a simple image of the original detailed (1-acre minimum), hierarchically organized vegetation cover map produced by computer classification of...

  6. GAP Land Cover - Vector

    Data.gov (United States)

    Minnesota Department of Natural Resources — This vector dataset is a detailed (1-acre minimum), hierarchically organized vegetation cover map produced by computer classification of combined two-season pairs of...

  7. Projected 2020 Land Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — Projected 2020 land cover was developed to provide one scenario of development in the year 2020. It was used to generate several metrics to compare to 1992 metrics...

  8. Development and Trialling of a Graduated Descriptors Tool for Australian Pharmacy Students

    Science.gov (United States)

    Stupans, Ieva; Owen, Susanne; McKauge, Leigh; Pont, Lisa; Ryan, Greg; Woulfe, Jim

    2012-01-01

    Profession-derived competency standards are key determinants for curriculum and assessment in many professional university programmes. An Australian Learning and Teaching Council funded project used a participatory action research approach to enable the collaborative development of a graduated (or incremental) descriptors tool related to…

  9. Higher-order linear matrix descriptor differential equations of Apostol-Kolodner type

    Directory of Open Access Journals (Sweden)

    2009-02-01

    Full Text Available In this article, we study a class of linear rectangular matrix descriptor differential equations of higher-order whose coefficients are square constant matrices. Using the Weierstrass canonical form, the analytical formulas for the solution of this general class is analytically derived, for consistent and non-consistent initial conditions.

  10. CBS-QB3 calculation of quantum chemical molecular descriptors of isomeric thiadiazoles.

    Science.gov (United States)

    Glossman-Mitnik, Daniel

    2006-12-01

    The results of the calculation of several molecular descriptors of isomeric thiadiazoles through the CBS-QB3 model chemistry are presented in this work. The results could be useful in quantitative structure-activity relationship (QSAR) or quantitative structure-property relationship (QSPR) studies of derivatives of the nitrogen-containing analogs of thiophene.

  11. DASC: Robust Dense Descriptor for Multi-Modal and Multi-Spectral Correspondence Estimation.

    Science.gov (United States)

    Kim, Seungryong; Min, Dongbo; Ham, Bumsub; Do, Minh N; Sohn, Kwanghoon

    2017-09-01

    Establishing dense correspondences between multiple images is a fundamental task in many applications. However, finding a reliable correspondence between multi-modal or multi-spectral images still remains unsolved due to their challenging photometric and geometric variations. In this paper, we propose a novel dense descriptor, called dense adaptive self-correlation (DASC), to estimate dense multi-modal and multi-spectral correspondences. Based on an observation that self-similarity existing within images is robust to imaging modality variations, we define the descriptor with a series of an adaptive self-correlation similarity measure between patches sampled by a randomized receptive field pooling, in which a sampling pattern is obtained using a discriminative learning. The computational redundancy of dense descriptors is dramatically reduced by applying fast edge-aware filtering. Furthermore, in order to address geometric variations including scale and rotation, we propose a geometry-invariant DASC (GI-DASC) descriptor that effectively leverages the DASC through a superpixel-based representation. For a quantitative evaluation of the GI-DASC, we build a novel multi-modal benchmark as varying photometric and geometric conditions. Experimental results demonstrate the outstanding performance of the DASC and GI-DASC in many cases of dense multi-modal and multi-spectral correspondences.

  12. Descriptors for predicting the lattice constant of body centered cubic crystal

    Science.gov (United States)

    Takahashi, Keisuke; Takahashi, Lauren; Baran, Jakub D.; Tanaka, Yuzuru

    2017-05-01

    The prediction of the lattice constant of binary body centered cubic crystals is performed in terms of first principle calculations and machine learning. In particular, 1541 binary body centered cubic crystals are calculated using density functional theory. Results from first principle calculations, corresponding information from periodic table, and mathematically tailored data are stored as a dataset. Data mining reveals seven descriptors which are key to determining the lattice constant where the contribution of descriptors is also discussed and visualized. Support vector regression (SVR) technique is implemented to train the data where the predicted lattice constants have the mean score of 83.6% accuracy via cross-validation and maximum error of 4% when compared to experimentally determined lattice constants. In addition, trained SVR is successful in predicting material combinations from a desired lattice constant. Thus, a set of descriptors for determining the lattice constant is identified and can be used as a base descriptor for lattice constants of further complex crystals. This would allow for the acceleration of the search for lattice constants of desired atomic compositions as well as the prediction of new materials based on a specified lattice constant.

  13. Number of outer electrons as descriptor for adsorption processes on transition metals and their oxides

    DEFF Research Database (Denmark)

    Calle-Vallejo, Federico; Inoglu, Nilay G.; Su, Hai-Yan;

    2013-01-01

    The trends in adsorption energies of the intermediates of the oxygen reduction and evolution reactions on transition metals and their oxides are smoothly captured by the number of outer electrons. This unique descriptor permits the construction of predictive adsorption-energy grids and explains...... the existence of scaling relationships among these compounds....

  14. A Hybrid FPGA/Coarse Parallel Processing Architecture for Multi-modal Visual Feature Descriptors

    DEFF Research Database (Denmark)

    Jensen, Lars Baunegaard With; Kjær-Nielsen, Anders; Alonso, Javier Díaz

    2008-01-01

    This paper describes the hybrid architecture developed for speeding up the processing of so-called multi-modal visual primitives which are sparse image descriptors extracted along contours. In the system, the first stages of visual processing are implemented on FPGAs due to their highly parallel...

  15. Positivity and stability of fractional descriptor time–varying discrete–time linear systems

    Directory of Open Access Journals (Sweden)

    Kaczorek Tadeusz

    2016-03-01

    Full Text Available The Weierstrass–Kronecker theorem on the decomposition of the regular pencil is extended to fractional descriptor time-varying discrete-time linear systems. A method for computing solutions of fractional systems is proposed. Necessary and sufficient conditions for the positivity of these systems are established.

  16. The Optimal Linear Quadratic Feedback State Regulator Problem for Index One Descriptor Systems

    NARCIS (Netherlands)

    Engwerda, J.C.; Salmah, Y.; Wijayanti, I.E.

    2008-01-01

    In this note we present both necessary and sufficient conditions for the existence of a linear static state feedback controller if the system is described by an index one descriptor system. A priori no definiteness restrictions are made w.r.t. the quadratic performance criterium. It is shown that in

  17. Segmental HOG: new descriptor for glomerulus detection in kidney microscopy image.

    Science.gov (United States)

    Kato, Tsuyoshi; Relator, Raissa; Ngouv, Hayliang; Hirohashi, Yoshihiro; Takaki, Osamu; Kakimoto, Tetsuhiro; Okada, Kinya

    2015-09-30

    The detection of the glomeruli is a key step in the histopathological evaluation of microscopic images of the kidneys. However, the task of automatic detection of the glomeruli poses challenges owing to the differences in their sizes and shapes in renal sections as well as the extensive variations in their intensities due to heterogeneity in immunohistochemistry staining. Although the rectangular histogram of oriented gradients (Rectangular HOG) is a widely recognized powerful descriptor for general object detection, it shows many false positives owing to the aforementioned difficulties in the context of glomeruli detection. A new descriptor referred to as Segmental HOG was developed to perform a comprehensive detection of hundreds of glomeruli in images of whole kidney sections. The new descriptor possesses flexible blocks that can be adaptively fitted to input images in order to acquire robustness for the detection of the glomeruli. Moreover, the novel segmentation technique employed herewith generates high-quality segmentation outputs, and the algorithm is assured to converge to an optimal solution. Consequently, experiments using real-world image data revealed that Segmental HOG achieved significant improvements in detection performance compared to Rectangular HOG. The proposed descriptor for glomeruli detection presents promising results, and it is expected to be useful in pathological evaluation.

  18. SVM Based Descriptor Selection and Classification of Neurodegenerative Disease Drugs for Pharmacological Modeling.

    Science.gov (United States)

    Shahid, Mohammad; Shahzad Cheema, Muhammad; Klenner, Alexander; Younesi, Erfan; Hofmann-Apitius, Martin

    2013-03-01

    Systems pharmacological modeling of drug mode of action for the next generation of multitarget drugs may open new routes for drug design and discovery. Computational methods are widely used in this context amongst which support vector machines (SVM) have proven successful in addressing the challenge of classifying drugs with similar features. We have applied a variety of such SVM-based approaches, namely SVM-based recursive feature elimination (SVM-RFE). We use the approach to predict the pharmacological properties of drugs widely used against complex neurodegenerative disorders (NDD) and to build an in-silico computational model for the binary classification of NDD drugs from other drugs. Application of an SVM-RFE model to a set of drugs successfully classified NDD drugs from non-NDD drugs and resulted in overall accuracy of ∼80 % with 10 fold cross validation using 40 top ranked molecular descriptors selected out of total 314 descriptors. Moreover, SVM-RFE method outperformed linear discriminant analysis (LDA) based feature selection and classification. The model reduced the multidimensional descriptors space of drugs dramatically and predicted NDD drugs with high accuracy, while avoiding over fitting. Based on these results, NDD-specific focused libraries of drug-like compounds can be designed and existing NDD-specific drugs can be characterized by a well-characterized set of molecular descriptors.

  19. The influence of certain molecular descriptors of fecal elimination of angiotensin II receptor antagonists

    Directory of Open Access Journals (Sweden)

    Trbojević-Stanković Jasna B.

    2015-01-01

    Full Text Available Angiotensin II receptor antagonists (ARBs modulate the function of the renin-angiotensin-aldosterone system and are commonly prescribed antihypertensive drugs, especially in patients with renal failure. In this study, the relationship between several molecular properties of seven ARBs (candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan and their fecal elimination data obtained from the literature were investigated. The ARB molecular descriptors were calculated using three software packages. Simple linear regression analysis showed the best 2 correlation between fecal elimination data and lipophilicity descriptor, ClogP values (R2 = 0.725. Multiple linear regression was applied to examine the correlation of ARBs’ fecal elimination data with their lipophilicity and one additional, calculated descriptor. The best correlation (R2 = 0.909 with an acceptable probability value, P <0.05 was established between the ARB fecal elimination data and their lipophilicity and aqueous solubility data. Applying computed molecular descriptors for evaluating drug elimination is of great importance in drug research.

  20. Is there life after guidance? Developments on the Marine Strategy Framework Directive ‘Eutrophication’ descriptor

    DEFF Research Database (Denmark)

    Ferreira, J.G.; Andersen, Jesper; Borja, S.B.

    In early 2011 the authors of this presentation completed a guidance document for MSFD Descriptor 5, Eutrophication. In mid-2011, the science supporting that document was published in the journal Estuarine, Coastal, and Shelf Science. In this talk we review the main findings of the guidance docume...

  1. Simultaneous stabilization of a class of nonlinear descriptor systems via Hamiltonian function method

    Institute of Scientific and Technical Information of China (English)

    SUN LiYing; WANG YuZhen

    2009-01-01

    This paper studies simultaneous stabilization of a class of nonlinear descriptor systems via the Hamiltonlan function method.Firstly,based on the Hamiltonian realization of the nonlinear descriptor systems and a suitable output feedback,two nonlinear descriptor systems are equivalently transformed into two nonlinear Hamiltonian differential-algebraic systems by a nonsingular transformation,and a sufficient condition for two closed-loop systems to be impulse-free is given.The two systems are then combined to generate an augmented dissipative Hamiltonian differential-algebraic system by using the system-augmentation technique,based on which a simultaneous stabilization controller and a robust simultaneous stabilization controller are designed for the two systems.Secondly,the case of more than two nonlinear descriptor systems is investigated,and two new results are proposed for the simultaneous stabilization and robust simultaneous stabilization,respectively.Finally,an illustrative example is studied by using the results proposed in this paper,and simulations show that the simultaneous stabilization controllers obtained in this paper work very well.

  2. Normalized maximum intensity time ratio maps and morphological descriptors for assessment of malignancy in MR mammography.

    Science.gov (United States)

    Ertas, Gokhan; Gulcur, H Ozcan; Tunaci, Mehtap

    2008-05-01

    Effectiveness of morphological descriptors based on normalized maximum intensity-time ratio (nMITR) maps generated using a 3 x 3 pixel moving mask on dynamic contrast-enhanced magnetoresistance (MR) mammograms are studied for assessment of malignancy. After a rough indication of volume of interest on the nMITR maps, lesions are automatically segmented. Two-dimensional (2D) convexity, normalized complexity, extent, and eccentricity as well as three-dimensional (3D) versions of these descriptors and contact surface area ratio are computed. On a data set consisting of dynamic contrast-enhanced MR DCE-MR mammograms from 51 women that contain 26 benign and 32 malignant lesions, 3D convexity, complexity, and extent are found to reflect aggressiveness of malignancy better than 2D descriptors. Contact surface area ratio which is easily adaptable to different imaging resolutions is found to be the most significant and accurate descriptor (75% sensitivity, 88% specificity, 89% positive predictive values, and 74% negative predictive values).

  3. Singular linear quadratic performance with the worst disturbance rejection for descriptor systems

    Institute of Scientific and Technical Information of China (English)

    Li CHEN

    2006-01-01

    This paper deals with the problem of singular linear quadratic performance with the worst-disturbance rejection for descriptor systems. Under the conditions we give, the worst-disturbance and the optimal control-state pair are unique respectively, the optimal control can be synthesized as state feedback and the closed-loop system is regular, stable and impulse-free.

  4. 3D face recognition based on multiple keypoint descriptors and sparse representation.

    Directory of Open Access Journals (Sweden)

    Lin Zhang

    Full Text Available Recent years have witnessed a growing interest in developing methods for 3D face recognition. However, 3D scans often suffer from the problems of missing parts, large facial expressions, and occlusions. To be useful in real-world applications, a 3D face recognition approach should be able to handle these challenges. In this paper, we propose a novel general approach to deal with the 3D face recognition problem by making use of multiple keypoint descriptors (MKD and the sparse representation-based classification (SRC. We call the proposed method 3DMKDSRC for short. Specifically, with 3DMKDSRC, each 3D face scan is represented as a set of descriptor vectors extracted from keypoints by meshSIFT. Descriptor vectors of gallery samples form the gallery dictionary. Given a probe 3D face scan, its descriptors are extracted at first and then its identity can be determined by using a multitask SRC. The proposed 3DMKDSRC approach does not require the pre-alignment between two face scans and is quite robust to the problems of missing data, occlusions and expressions. Its superiority over the other leading 3D face recognition schemes has been corroborated by extensive experiments conducted on three benchmark databases, Bosphorus, GavabDB, and FRGC2.0. The Matlab source code for 3DMKDSRC and the related evaluation results are publicly available at http://sse.tongji.edu.cn/linzhang/3dmkdsrcface/3dmkdsrc.htm.

  5. Analysis and Overview of NQF Level Descriptors in European Countries. Working Paper No 19

    Science.gov (United States)

    Bjørnåvold, Jens; Grm, Slava Pevec

    2013-01-01

    Level descriptors are essential elements of national qualifications frameworks being established across Europe. They define what is meant by learning outcomes, describing what an individual is expected to know, be able to do and understand, having acquired a qualification at a particular level. This Cedefop working paper shows that most of the 36…

  6. Descriptors for unprofessional behaviours of medical students: a systematic review and categorisation.

    Science.gov (United States)

    Mak-van der Vossen, Marianne; van Mook, Walther; van der Burgt, Stéphanie; Kors, Joyce; Ket, Johannes C F; Croiset, Gerda; Kusurkar, Rashmi

    2017-09-15

    Developing professionalism is a core task in medical education. Unfortunately, it has remained difficult for educators to identify medical students' unprofessionalism, because, among other reasons, there are no commonly adopted descriptors that can be used to document students' unprofessional behaviour. This study aimed to generate an overview of descriptors for unprofessional behaviour based on research evidence of real-life unprofessional behaviours of medical students. A systematic review was conducted searching PubMed, Ebsco/ERIC, Ebsco/PsycINFO and Embase.com from inception to 2016. Articles were reviewed for admitted or witnessed unprofessional behaviours of undergraduate medical students. The search yielded 11,963 different studies, 46 met all inclusion criteria. We found 205 different descriptions of unprofessional behaviours, which were coded into 30 different descriptors, and subsequently classified in four behavioural themes: failure to engage, dishonest behaviour, disrespectful behaviour, and poor self-awareness. This overview provides a common language to describe medical students' unprofessional behaviour. The framework of descriptors is proposed as a tool for educators to denominate students' unprofessional behaviours. The found behaviours can have various causes, which should be explored in a discussion with the student about personal, interpersonal and/or institutional circumstances in which the behaviour occurred. Explicitly denominating unprofessional behaviour serves two goals: [i] creating a culture in which unprofessional behaviour is acknowledged, [ii] targeting students who need extra guidance. Both are important to avoid unprofessional behaviour among future doctors.

  7. Artificial neural network prediction of the psychometric activities of phenylalkylamines using DFT-calculated molecular descriptors

    Directory of Open Access Journals (Sweden)

    MINA HAGHDADI

    2010-10-01

    Full Text Available In the present work, a quantitative structure–activity relationship (QSAR method was used to predict the psychometric activity values (as mescaline unit, log MU of 48 phenylalkylamine derivatives from their density functional theory (DFT calculated molecular descriptors and an artificial neural network (ANN. In the first step, the molecular descriptors were obtained by DFT calculation at the 6-311G level of theory. Then the stepwise multiple linear regression method was employed to screen the descriptor spaces. In the next step, an artificial neural network and multiple linear regressions (MLR models were developed to construct nonlinear and linear QSAR models, respectively. The standard errors in the prediction of log MU by the MLR model were 0.398, 0.443 and 0.427 for training, internal and external test sets, respectively, while these values for the ANN model were 0.132, 0.197 and 0.202, respectively. The obtained results show the applicability of QSAR approaches by using ANN techniques in prediction of log MU of phenylalkylamine derivatives from their DFT-calculated molecular descriptors.

  8. A comparison of feature detectors and descriptors for object class matching

    DEFF Research Database (Denmark)

    Hietanen, Antti; Lankinen, Jukka; Kämäräinen, Joni-Kristian

    2016-01-01

    appearance variation can be large. We extend the benchmarks to the class matching setting and evaluate state-of-the-art detectors and descriptors with Caltech and ImageNet classes. Our experiments provide important findings with regard to object class matching: (1) the original SIFT is still the best...

  9. Comparing Local Descriptors and Bags of Visual Words to Deep Convolutional Neural Networks for Plant Recognition

    NARCIS (Netherlands)

    Pawara, Pornntiwa; Okafor, Emmanuel; Surinta, Olarik; Schomaker, Lambertus; Wiering, Marco

    2017-01-01

    The use of machine learning and computer vision methods for recognizing different plants from images has attracted lots of attention from the community. This paper aims at comparing local feature descriptors and bags of visual words with different classifiers to deep convolutional neural networks (C

  10. Prediction of solid oxide fuel cell cathode activity with first-principles descriptors

    DEFF Research Database (Denmark)

    Lee, Yueh-Lin; Kleis, Jesper; Rossmeisl, Jan

    2011-01-01

    In this work we demonstrate that the experimentally measured area specific resistance and oxygen surface exchange of solid oxide fuel cell cathode perovskites are strongly correlated with the first-principles calculated oxygen p-band center and vacancy formation energy. These quantities...... are therefore descriptors of catalytic activity that can be used in the first-principles design of new SOFC cathodes....

  11. Symbol recognition via statistical integration of pixel-level constraint histograms: a new descriptor.

    Science.gov (United States)

    Yang, Su

    2005-02-01

    A new descriptor for symbol recognition is proposed. 1) A histogram is constructed for every pixel to figure out the distribution of the constraints among the other pixels. 2) All the histograms are statistically integrated to form a feature vector with fixed dimension. The robustness and invariance were experimentally confirmed.

  12. Object Tracking Using Adaptive Covariance Descriptor and Clustering-Based Model Updating for Visual Surveillance

    Directory of Open Access Journals (Sweden)

    Lei Qin

    2014-05-01

    Full Text Available We propose a novel approach for tracking an arbitrary object in video sequences for visual surveillance. The first contribution of this work is an automatic feature extraction method that is able to extract compact discriminative features from a feature pool before computing the region covariance descriptor. As the feature extraction method is adaptive to a specific object of interest, we refer to the region covariance descriptor computed using the extracted features as the adaptive covariance descriptor. The second contribution is to propose a weakly supervised method for updating the object appearance model during tracking. The method performs a mean-shift clustering procedure among the tracking result samples accumulated during a period of time and selects a group of reliable samples for updating the object appearance model. As such, the object appearance model is kept up-to-date and is prevented from contamination even in case of tracking mistakes. We conducted comparing experiments on real-world video sequences, which confirmed the effectiveness of the proposed approaches. The tracking system that integrates the adaptive covariance descriptor and the clustering-based model updating method accomplished stable object tracking on challenging video sequences.

  13. Mammographic density descriptors of novel phantom images: effect of clustered lumpy backgrounds

    Science.gov (United States)

    Li, Yanpeng; Brennan, Patrick C.; Ryan, Elaine

    2014-03-01

    Mammographic breast density (MBD) is a risk factor for breast cancer. Both qualitative and quantitative methods have been used to evaluate MBD. However as it is impossible to measure the actual weight or volume of fibroglandular tissue evident on a mammogram, therefore it is hard to know the true correlation between measured mammographic density and the fibroglandular tissue volume. A phantom system has been developed that represents glandular tissue within an adipose tissue structure. Although a previous study has found strong correlation between the synthesised glandular mass and several image descriptors, it is not known if the correlation is still present when a high level of background noise is introduced. The background noise is required to more realistically simulate clinical image appearance. The aim of this study is to investigate if the correlation between percentage density, integrated density, and standard deviation of mean grey value of the whole phantom and simulated glandular tissue mass is affected by background noise being added to the phantom images. For a set of one hundred phantom mammographic images, clustered lumpy backgrounds were synthesised and superimposed onto phantom images. The correlation between the synthesised glandular mass and the image descriptors were calculated. The results showed the correlation is strong and statistically significant for the above three descriptors with r is 0.7597, 0.8208, and 0.7167 respectively. This indicates these descriptors may be used to assess breast fibroglandular tissue content of the breast using mammographic images.

  14. A novel phantom system facilitating better descriptors of density within mammographic images

    Science.gov (United States)

    Li, Yanpeng; Brennan, Patrick C.; Nickson, Carolyn; Pietrzyk, Mariusz W.; Al Mousa, Dana; Ryan, Elaine

    2013-03-01

    High mammographic density is a risk factor for breast cancer. As it is impossible to measure actual weight or volume of fibroglandular tissue evident within a mammogram, it is hard to know the correlation between measured mammographic density and the actual fibroglandular tissue volume. The aim of this study is to develop a phantom that represents glandular tissue within an adipose tissue structure so that correlations between image feature descriptors and the synthesised glandular structure can be accurately quantified. In this phantom study, ten different weights of fine steel wool were put into gelatine to simulate breast structure. Image feature descriptors are investigated for both the whole phantom image and the simulated density. Descriptors included actual area and percentage area of density, mean pixel intensity for the whole image and dense area, standard deviation of mean intensity, and integrated pixel density which is the production of area and mean intensity. The results show high level correlation between steel-wool weight and percentage density measured on images (r = 0.8421), and the integrated pixel density of dense area (r = 0.8760). The correlation is significant for mean intensity standard deviation for the whole phantom (r = 0.8043). This phantom study may help identify more accurate descriptors of mammographic density, thus facilitating better assessments of fibroglandular tissue appearances.

  15. Development and Trialling of a Graduated Descriptors Tool for Australian Pharmacy Students

    Science.gov (United States)

    Stupans, Ieva; Owen, Susanne; McKauge, Leigh; Pont, Lisa; Ryan, Greg; Woulfe, Jim

    2012-01-01

    Profession-derived competency standards are key determinants for curriculum and assessment in many professional university programmes. An Australian Learning and Teaching Council funded project used a participatory action research approach to enable the collaborative development of a graduated (or incremental) descriptors tool related to…

  16. Local chemical potential, local hardness, and dual descriptors in temperature dependent chemical reactivity theory.

    Science.gov (United States)

    Franco-Pérez, Marco; Ayers, Paul W; Gázquez, José L; Vela, Alberto

    2017-05-31

    In this work we establish a new temperature dependent procedure within the grand canonical ensemble, to avoid the Dirac delta function exhibited by some of the second order chemical reactivity descriptors based on density functional theory, at a temperature of 0 K. Through the definition of a local chemical potential designed to integrate to the global temperature dependent electronic chemical potential, the local chemical hardness is expressed in terms of the derivative of this local chemical potential with respect to the average number of electrons. For the three-ground-states ensemble model, this local hardness contains a term that is equal to the one intuitively proposed by Meneses, Tiznado, Contreras and Fuentealba, which integrates to the global hardness given by the difference in the first ionization potential, I, and the electron affinity, A, at any temperature. However, in the present approach one finds an additional temperature-dependent term that introduces changes at the local level and integrates to zero. Additionally, a τ-hard dual descriptor and a τ-soft dual descriptor given in terms of the product of the global hardness and the global softness multiplied by the dual descriptor, respectively, are derived. Since all these reactivity indices are given by expressions composed of terms that correspond to products of the global properties multiplied by the electrophilic or nucleophilic Fukui functions, they may be useful for studying and comparing equivalent sites in different chemical environments.

  17. Validating Performance Level Descriptors (PLDs) for the AP® Environmental Science Exam

    Science.gov (United States)

    Reshetar, Rosemary; Kaliski, Pamela; Chajewski, Michael; Lionberger, Karen

    2012-01-01

    This presentation summarizes a pilot study conducted after the May 2011 administration of the AP Environmental Science Exam. The study used analytical methods based on scaled anchoring as input to a Performance Level Descriptor validation process that solicited systematic input from subject matter experts.

  18. Relationship between molecular descriptors and the enthalpies of sublimation of natural amino acids

    Science.gov (United States)

    Badelin, V. G.; Tyunina, V. V.; Girichev, G. V.; Tyunina, E. Yu.

    2016-07-01

    A multiparameter correlation between the enthalpies of sublimation and molecular descriptors of natural amino acids is proposed, based on generalized experimental and literature data on the heat effects of sublimation. The contributions from Van der Waals interactions, hydrogen bond formation, and electrostatic effects into enthalpy of sublimation has been evaluated using regression coefficients.

  19. Analysing written production competence descriptors for academic and professional purposes and their calibration to the CEFR

    Directory of Open Access Journals (Sweden)

    Joana Pierce McMahon

    2012-04-01

    Full Text Available The Common European Framework of Reference for Languages (CEFR “describes in a comprehensive way what language learners have to learn to do in order to use a language for communication and what knowledge and skills they have to develop so as to be able to act effectively” (Council of Europe, 2001: 1. This paper reports on the findings of two studies whose purpose was to assess written production competence descriptors meant for their inclusion into the Academic and Professional English Language Portfolio (ELP for students of engineering and architecture. The main objective of these studies was to establish whether the language competence descriptors were a satisfactory valid tool in their language programmes from the point of view of clarity, relevance and reliability, as perceived by the students and fellow English for Academic Purposes (EAP / English for Science and Technology (EST instructors. The studies shed light on how to improve unsatisfactory descriptors. Results show that the final descriptor lists were on the whole well calibrated and fairly well written: the great majority was considered valid for both teachers and students involved.

  20. Fourier Descriptor Analysis and Unification of Voice Range Profile Contours: Method and Applications

    Science.gov (United States)

    Pabon, Peter; Ternstrom, Sten; Lamarche, Anick

    2011-01-01

    Purpose: To describe a method for unified description, statistical modeling, and comparison of voice range profile (VRP) contours, even from diverse sources. Method: A morphologic modeling technique, which is based on Fourier descriptors (FDs), is applied to the VRP contour. The technique, which essentially involves resampling of the curve of the…

  1. Fourier Descriptor Analysis and Unification of Voice Range Profile Contours: Method and Applications

    Science.gov (United States)

    Pabon, Peter; Ternstrom, Sten; Lamarche, Anick

    2011-01-01

    Purpose: To describe a method for unified description, statistical modeling, and comparison of voice range profile (VRP) contours, even from diverse sources. Method: A morphologic modeling technique, which is based on Fourier descriptors (FDs), is applied to the VRP contour. The technique, which essentially involves resampling of the curve of the…

  2. Relationship between Dyspnea Descriptors and Underlying Causes of the Symptom; a Cross-sectional Study

    Directory of Open Access Journals (Sweden)

    Seyyed Mohammad Ali Sajadi

    2017-03-01

    Full Text Available Introduction: History taking and physical examination help clinicians identify the patient’s problem and effectively treat it. This study aimed to evaluate the descriptors of dyspnea in patients presenting to emergency department (ED with asthma, congestive heart failure (CHF, and chronic obstructive pulmonary disease (COPD. Method: This cross-sectional study was conducted on all patients presenting to ED with chief complaint of dyspnea, during 2 years. The patients were asked to describe their dyspnea by choosing three items from the valid and reliable questionnaire or articulating their sensation. The relationship between dyspnea descriptors and underlying cause of symptom was evaluated using SPSS version 16. Results: 312 patients with the mean age of 60.96±17.01 years were evaluated (53.2% male. Most of the patients were > 65 years old (48.7% and had basic level of education (76.9%.  "My breath doesn’t go out all the way" with 83.1%, “My chest feels tight " with 45.8%, and "I feel that my airway is obstructed" with 40.7%, were the most frequent dyspnea descriptors in asthma patients. "My breathing requires work" with 46.3%, "I feel that I am suffocating" with 31.5%, and "My breath doesn’t go out all the way" with 29.6%, were the most frequent dyspnea descriptors in COPD patients. "My breathing is heavy" with 74.4%, "A hunger for more air” with 24.4%, and "I cannot get enough air" with 23.2%, were the most frequent dyspnea descriptors in CHF patients. Except for “My breath does not go in all the way”, there was significant correlation between studied dyspnea descriptors and underlying disease (p = 0.001 for all analyses. Conclusion: It seems that dyspnea descriptors along with other findings from history and physical examination could be helpful in differentiating the causes of the symptom in patients presenting to ED suffering from dyspnea.  

  3. Real-time multi-modal rigid registration based on a novel symmetric-SIFT descriptor

    Institute of Scientific and Technical Information of China (English)

    Jian Chen; Jie Tian

    2009-01-01

    The purpose of image registration is to spatially align two or more single-modality images taken at different times,or several images acquired by multiple imaging modalities.Intensity-based registration usually requires optimization of the similarity metric between the images.However,global optimization techniques are too time-consuming,and local optimization techniques frequently fail to search the global transformation space because of the large initial misalignment of the two images.Moreover,for large non-overlapping area registration,the similarity metric cannot reach its optimum value when the two images are properly registered.In order to solve these problems,we propose a novel Symmetric Scale Invariant Feature Transform (symmetric-SIFT) descriptor and develop a fast multi-modal image registration technique.The proposed technique automatically generates a lot of highly distinctive symmetric-SIFT descriptors for two images,and the registration is performed by matching the corresponding descriptors over two images.These descriptors are invariant to image scale and rotation,and are partially invariant to affine transformation.Moreover,these descriptors are symmetric to contrast,which makes it suitable for multi-modal image registration.The proposed technique abandons the optimization and similarity metric strategy.It works with near real-time performance,and can deal with the large non-overlapping and large initial misalignment situations.Test cases involving scale change,large non-overlapping,and large initial misalignment on computed tomography (CT) and magnetic resonance (MR) datasets show that it needs much less runtime and achieves better accuracy when compared to other algorithms.(C) 2009 National Natural Science Foundation of China and Chinese Academy of Sciences.Published by Elsevier Limited and Science in China Press.All rights reserved.

  4. Climate under cover

    CERN Document Server

    Takakura, Tadashi

    2002-01-01

    1.1. INTRODUCTION Plastic covering, either framed or floating, is now used worldwide to protect crops from unfavorable growing conditions, such as severe weather and insects and birds. Protected cultivation in the broad sense, including mulching, has been widely spread by the innovation of plastic films. Paper, straw, and glass were the main materials used before the era of plastics. Utilization of plastics in agriculture started in the developed countries and is now spreading to the developing countries. Early utilization of plastic was in cold regions, and plastic was mainly used for protection from the cold. Now plastic is used also for protection from wind, insects and diseases. The use of covering techniques started with a simple system such as mulching, then row covers and small tunnels were developed, and finally plastic houses. Floating mulch was an exception to this sequence: it was introduced rather recently, although it is a simple structure. New development of functional and inexpensive films trig...

  5. Reusable pipe flange covers

    Energy Technology Data Exchange (ETDEWEB)

    Holden, James Elliott (Simpsonville, SC); Perez, Julieta (Houston, TX)

    2001-01-01

    A molded, flexible pipe flange cover for temporarily covering a pipe flange and a pipe opening includes a substantially round center portion having a peripheral skirt portion depending from the center portion, the center portion adapted to engage a front side of the pipe flange and to seal the pipe opening. The peripheral skirt portion is formed to include a plurality of circumferentially spaced tabs, wherein free ends of the flexible tabs are formed with respective through passages adapted to receive a drawstring for pulling the tabs together on a back side of the pipe flange.

  6. Covering tree with stars

    DEFF Research Database (Denmark)

    Baumbach, Jan; Guo, Jian-Ying; Ibragimov, Rashid

    2013-01-01

    We study the tree edit distance problem with edge deletions and edge insertions as edit operations. We reformulate a special case of this problem as Covering Tree with Stars (CTS): given a tree T and a set of stars, can we connect the stars in by adding edges between them such that the resulting ...

  7. Covering tree with stars

    DEFF Research Database (Denmark)

    Baumbach, Jan; Guo, Jiong; Ibragimov, Rashid

    2015-01-01

    We study the tree edit distance problem with edge deletions and edge insertions as edit operations. We reformulate a special case of this problem as Covering Tree with Stars (CTS): given a tree T and a set of stars, can we connect the stars in by adding edges between them such that the resulting ...

  8. Covering All Options

    Science.gov (United States)

    Kennedy, Mike

    2011-01-01

    The day a school opens its doors for the first time, the flooring will be new and untarnished. When the flooring is in such pristine condition, many flooring materials--carpeting, vinyl, terrazzo, wood or some other surface--will look good. But school and university planners who decide what kind of material covers the floors of their facilities…

  9. CORINE Land Cover 2006

    DEFF Research Database (Denmark)

    Stjernholm, Michael

    "CORINE land cover" er en fælleseuropæisk kortlægning af arealanvendelse/arealdække. Arealanvendelse/arealdække er i Danmark kortlagt efter CORINE metode og klasseopdeling med satellitbilleder fra 3 forskellige tidsperioder, fra begyndelsen af 1990'erne (CLC90), fra år 2000 (CLC2000) og fra år 2006...

  10. CORINE Land Cover 2006

    DEFF Research Database (Denmark)

    Stjernholm, Michael

    "CORINE land cover" er en fælleseuropæisk kortlægning af arealanvendelse/arealdække. Arealanvendelse/arealdække er i Danmark kortlagt efter CORINE metode og klasseopdeling med satellitbilleder fra 3 forskellige tidsperioder, fra begyndelsen af 1990'erne (CLC90), fra år 2000 (CLC2000) og fra år 2006...

  11. ELECTRON DONOR ACCEPTOR DESCRIPTORS OF THE SINGLE AND DOUBLE BONDED SUBSTITUENT AND HETEROATOM INCORPORATION EFFECTS. A REVIEW.

    Science.gov (United States)

    Mazurek, Andrzej

    2016-01-01

    The properties of the series of Electron Donor-Acceptor (EDA) descriptors of classical substituent effect (sEDA(I), pEDA(I)), double bonded substituent effect (sEDA(=), pEDA(=)), heteroatom incorporation effect in monocyclic systems (sEDA(II), pEDA(II)), and in ring-junction position (sEDA(III), pEDA(III)), are reviewed. The descriptors show the amount of electrons donated to or withdrawn from the σ-(sEDA) or π(pEDA) valence orbitals by the substituent or incorporant. The new descriptors are expected to enrich the potency of QSAR analyses in drug design and materials chemistry.

  12. Preview control for impulse-free continuous-time descriptor systems

    Science.gov (United States)

    Liao, Fucheng; Ren, Zhenqin; Tomizuka, Masayoshi; Wu, Jiang

    2015-06-01

    This paper studies the preview control problem of impulse-free linear continuous-time descriptor systems. The system is first decomposed into a normal system (i.e., slow subsystem) and an algebraic equation set, by restricted equivalent linear transformation. Then, applying the method of preview control theory to the slow subsystem, by taking derivatives on both the error vector and the state function, and with the error vector being a part of the new state vector, the augmented system is constructed and the tracking problem is transformed into a regulation problem. According to preview control theory, the controller of the augmented system can be obtained and the control input of the original descriptor system with preview function can be acquired by integrating on the controller of the augmented system. Both the stabilisability and detectability of the augmented system are discussed. Numerical simulation verifies the presented results.

  13. Extracting hand articulations from monocular depth images using curvature scale space descriptors

    Institute of Scientific and Technical Information of China (English)

    Shao-fan WANG[1; Chun LI[1; De-hui KONG[1; Bao-cai YIN[2,1,3

    2016-01-01

    We propose a framework of hand articulation detection from a monocular depth image using curvature scale space (CSS) descriptors. We extract the hand contour from an input depth image, and obtain the fingertips and finger-valleys of the contour using the local extrema of a modified CSS map of the contour. Then we recover the undetected fingertips according to the local change of depths of points in the interior of the contour. Compared with traditional appearance-based approaches using either angle detectors or convex hull detectors, the modified CSS descriptor extracts the fingertips and finger-valleys more precisely since it is more robust to noisy or corrupted data; moreover, the local extrema of depths recover the fingertips of bending fingers well while traditional appearance-based approaches hardly work without matching models of hands. Experimental results show that our method captures the hand articulations more precisely compared with three state-of-the-art appearance-based approaches.

  14. Extracting hand articulations from monocular depth images using curvature scale space descriptors

    Institute of Scientific and Technical Information of China (English)

    Shao-fan WANG; Chun LI; De-hui KONG; Bao-cai YIN

    2016-01-01

    We propose a framework of hand articulation detection from a monocular depth image using curvature scale space (CSS) descriptors. We extract the hand contour from an input depth image, and obtain the fingertips and finger-valleys of the contour using the local extrema of a modified CSS map of the contour. Then we recover the undetected fingertips according to the local change of depths of points in the interior of the contour. Compared with traditional appearance-based approaches using either angle detectors or convex hull detectors, the modified CSS descriptor extracts the fingertips and finger-valleys more precisely since it is more robust to noisy or corrupted data;moreover, the local extrema of depths recover the fingertips of bending fingers well while traditional appearance-based approaches hardly work without matching models of hands. Experimental results show that our method captures the hand articulations more precisely compared with three state-of-the-art appearance-based approaches.

  15. Image Identification Based on Shape and Color Descriptors and Its Application to Ornamental Leaf

    Directory of Open Access Journals (Sweden)

    Kohei Arai

    2013-08-01

    Full Text Available Human has a duty to preserve the nature, preserving the plant is one of the examples. This research has an emphasis on ornamental plant that has functionality not only as ornament but also as medicine. Although in Indonesia, in general this plant is cultivated in front of the house; only few people know about its medicinal function. Considering this easiness to obtain and its medicinal function, this plant has to be an initial treatment or option towards full chemical-based medicines. This research proposes a system which able to identify properly ornamental plant from its leaf utilizing its shape or color features. Shape descriptor represented by Dyadic Wavelet Transformation and Zernike Complex Moment, and HSV-based color histogram as color descriptor. This research provides benefit of these three methods to solve various test aspects. It was obtained 81.77% of overall average-testing performance.

  16. Correlation of Critical Micelle Concentration of Sodium Alkyl Benzenesulfonates with Molecular Descriptors

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The hydrophobic-hydrophilic segment geometries of 36 sodium alkyl benzenesulfonates were fully optimized and calculated by abini-tio RHF/6-31G(d), quantum chemical data such as the charge density, the energy of molecular orbital and the dipole moment were obtained. Based on two topological descriptors and one quantum chemical descriptor, a significant quantitative structure-property relationship (QSPR) model for the critical micelle concentration (cmc) of sodium alkyl benzenesulfonate surfactants was obtained by using the multiple linear regression technique. The good correlation coefficient of R2 (0.980) and cross-validation correlation coefficient R2cv (0.974) indicate the excellent capability and stability of the regression equation developed. In addition, linear relationships between logarithm of cmc and the dipole moment of surfactant hydrophobic hydrophilic segments for each homologous series have also been established with high correlation coefficient.

  17. Metal Oxide Nanomaterial QNAR Models: Available Structural Descriptors and Understanding of Toxicity Mechanisms

    Directory of Open Access Journals (Sweden)

    Jiali Ying

    2015-10-01

    Full Text Available Metal oxide nanomaterials are widely used in various areas; however, the divergent published toxicology data makes it difficult to determine whether there is a risk associated with exposure to metal oxide nanomaterials. The application of quantitative structure activity relationship (QSAR modeling in metal oxide nanomaterials toxicity studies can reduce the need for time-consuming and resource-intensive nanotoxicity tests. The nanostructure and inorganic composition of metal oxide nanomaterials makes this approach different from classical QSAR study; this review lists and classifies some structural descriptors, such as size, cation charge, and band gap energy, in recent metal oxide nanomaterials quantitative nanostructure activity relationship (QNAR studies and discusses the mechanism of metal oxide nanomaterials toxicity based on these descriptors and traditional nanotoxicity tests.

  18. Characterization of structural vibration: Field descriptors based on energy density and intensity

    Science.gov (United States)

    Linjama, Jukka

    Measurement of energy flow in acoustical and vibrational fields is usually based on the detection of one linear field quantity (e.g. sound pressure) and its spatial gradient, two transducers being used for the measurement. This report first reviews the quantities which can be obtained from the measurement of acoustical intensity with a two-microphone probe: intensity and the energy densities. A set of 'field descriptors', relative quantities giving a measure of propagating (active) character of the waves in the sound field, is proposed. These energetic quantities are based entirely on the transversal velocity measured and the gradient of that velocity, and are available when the two-transducer method of bending wave intensity is used. Examples of the energy densities and field descriptors measured in an aluminum plate are presented, and proposals for further work are given.

  19. A comparative study of local descriptors for Arabic character recognition on mobile devices

    Science.gov (United States)

    Tounsi, Maroua; Moalla, Ikram; Alimi, Adel M.; Lebourgeois, Franck

    2015-02-01

    Nowadays, the number of mobile applications based on image registration and recognition is increasing. Most interesting applications include mobile translator which can read text characters in the real world and translates it into the native language instantaneously. In this context, we aim to recognize characters in natural scenes by computing significant points so called key points or features/interest points in the image. So, it will be important to compare and evaluate features descriptors in terms of matching accuracy and processing time in a particular context of natural scene images. In this paper, we were interested on comparing the efficiency of the binary features as alternatives to the traditional SIFT and SURF in matching Arabic characters descended from natural scenes. We demonstrate that the binary descriptor ORB yields not only to similar results in terms of matching characters performance that the famous SIFT but also to faster computation suitable for mobile applications.

  20. Optimal guaranteed cost control for fuzzy descriptor systems with time-varying delay

    Institute of Scientific and Technical Information of China (English)

    Tian Weihua; Zhang Huaguang

    2008-01-01

    Based on the delay-independent rule, the problem of optimal guaranteed cost control for a class of Takagi-Sugeno (T-S) fuzzy descriptor systems with time-varying delay is studied. A linear quadratic cost function is considered as the performance index of the closed-loop system. Sufficient conditions for the existence of guaranteed cost controllers via state feedback are given in terms of linear matrix inequalities (LMIs), and the design of an optimal guaranteed cost controller can be reduced to a convex optimization problem. It is shown that the designed controller not only guarantees the asymptotic stability of the closed-loop fuzzy descriptor delay system, but also provides an optimized upper bound of the guaranteed cost. At last, a numerical example is given to illustrate the effectiveness of the proposed method and the perfect performance of the optimal guaranteed cost controller.

  1. Inductive QSAR Descriptors. Distinguishing Compounds with Antibacterial Activity by Artificial Neural Networks

    Directory of Open Access Journals (Sweden)

    Artem Cherkasov

    2005-01-01

    Full Text Available Abstract: On the basis of the previous models of inductive and steric effects, ‘inductive’ electronegativity and molecular capacitance, a range of new ‘inductive’ QSAR descriptors has been derived. These molecular parameters are easily accessible from electronegativities and covalent radii of the constituent atoms and interatomic distances and can reflect a variety of aspects of intra- and intermolecular interactions. Using 34 ‘inductive’ QSAR descriptors alone we have been able to achieve 93% correct separation of compounds with- and without antibacterial activity (in the set of 657. The elaborated QSAR model based on the Artificial Neural Networks approach has been extensively validated and has confidently assigned antibacterial character to a number of trial antibiotics from the literature.

  2. Molecular Descriptors Family on Structure Activity Relationships 3. Antituberculotic Activity of some Polyhydroxyxanthones

    Directory of Open Access Journals (Sweden)

    Sorana BOLBOACĂ

    2005-06-01

    Full Text Available The antituberculotic activity of some polyhydroxyxanthones was estimated using the Molecular Descriptors Family on Structure Activity Relationships methodology. From a total number of 298110 real and distinct calculated descriptors, 94843 were significantly different and entered into multiple linear regression analysis. The best performing bi-varied model was obtained by use of all polyhydroxyxanthones. The MDF SAR model was validated splitting the molecules into training and test sets. A correlated correlations analysis was applied in other to compare the MDF SAR models with the previous SAR model. The prediction ability of antituberculotic activity of polyhydroxyxanthones with MDF SAR methodology is sustained by three arguments: leave-one-out procedure, training vs. test procedure, and the correlated correlations analysis. Looking at the bi-varied MDF SAR model, we can conclude that the antituberculotic activity of polyhydroxyxanthones is almost of geometrical nature (99% and is strongly dependent on partial atomic charge and group electronegativity.

  3. Static sign language recognition using 1D descriptors and neural networks

    Science.gov (United States)

    Solís, José F.; Toxqui, Carina; Padilla, Alfonso; Santiago, César

    2012-10-01

    A frame work for static sign language recognition using descriptors which represents 2D images in 1D data and artificial neural networks is presented in this work. The 1D descriptors were computed by two methods, first one consists in a correlation rotational operator.1 and second is based on contour analysis of hand shape. One of the main problems in sign language recognition is segmentation; most of papers report a special color in gloves or background for hand shape analysis. In order to avoid the use of gloves or special clothing, a thermal imaging camera was used to capture images. Static signs were picked up from 1 to 9 digits of American Sign Language, a multilayer perceptron reached 100% recognition with cross-validation.

  4. Design of PI observers for continuous-time descriptor linear systems.

    Science.gov (United States)

    Wu, Ai-Guo; Duan, Guang-Ren

    2006-12-01

    A parametric design approach for proportional-integral (PI) observers for continuous-time descriptor linear systems is proposed based on a complete general parametric solution to the generalized Sylvester matrix equation. The proposed approach provides complete parameterizations for all the observer gain matrices, gives the parametric expression for the corresponding finite left eigenvector matrix of the observer system matrix, realizes elimination of impulsive responses, and guarantees the regularity of the observer system. The design method offers all the degrees of design freedom, which can be utilized to achieve various desired system specifications and performances and, thus, has great potentials in applications. A numerical example is employed to show the design procedure and illustrate the effect of the proposed approach. Simulation results show a satisfactory tracking performance for descriptor linear systems.

  5. Robust model-reference control for descriptor linear systems subject to parameter uncertainties

    Institute of Scientific and Technical Information of China (English)

    Guangren DUAN; Biao ZHANG

    2007-01-01

    Robust model-reference control for descriptor linear systems with structural parameter uncertainties is investigated. A sufficient condition for existing a model-reference zero-error asymptotic tracking controller is given. It is shown that the robust model reference control problem can be decomposed into two subproblems: a robust state feedback stabilization problem for descriptor systems subject to parameter uncertainties and a robust compensation problem. The latter aims to find three coefficient matrices which satisfy four matrix equations and simultaneously minimize the effect of the uncertainties to the tracking error. Based on a complete parametric solution to a class of generalized Sylvester matrix equations, the robust compensation problem is converted into a minimization problem with quadratic cost and linear constraints. A numerical example shows the effect of the proposed approach.

  6. Robust H-infinity fault-tolerant control for uncertain descriptor systems by dynamical compensators

    Institute of Scientific and Technical Information of China (English)

    Bing LIANG; Guangren DUAN

    2004-01-01

    The problem of robust H-infinity fault-tolerant control against sensor failures for a class of uncertain descriptor systems via dynamical compensators is considered.Based on H-infinity theory in descriptor systems,a sufficient condition for the existence of dynamical compensators with H-infinity fault-tolerant function is derived and expressions for the gain matrices in the compensators are presented.The dynamical compensator guarantees that the resultant colsed-loop system is admissible;furthermore,it maintains certain H-infinity norm performance in the normal condition as well as in the event of sensor failures and parameter uncertainties.A numerical example shows the effect of the proposed method.

  7. A high capacity multiple watermarking scheme based on Fourier descriptor and Sudoku

    Science.gov (United States)

    Zhang, Li; Zheng, Huimin

    2015-12-01

    Digital watermark is a type of technology to hide some significant information which is mainly used to protect digital data. A high capacity multiple watermarking method is proposed, which adapts the Fourier descriptor to pre-process the watermarks, while a Sudoku puzzle is used as a reference matrix in embedding process and a key in extraction process. It can dramatically reduce the required capacity by applying Fourier descriptor. Meanwhile, the security of watermarks can be guaranteed due to the Sudoku puzzle. Unlike previous algorithms applying Sudoku puzzle in spatial domain, the proposed algorithm works in transformed domain by applying LWT2.In addition, the proposed algorithm can detect the temper location accurately. The experimental results demonstrated that the goals mentioned above have been achieved.

  8. Genetic dissimilarity among sweet potato genotypes using morphological and molecular descriptors

    Directory of Open Access Journals (Sweden)

    Elisângela Knoblauch Viega de Andrade

    2017-08-01

    Full Text Available This study aimed to evaluate the genetic dissimilarity among sweet potato genotypes using morphological and molecular descriptors. The experiment was conducted in the Olericulture Sector at Federal University of Jequitinhonha and Mucuri Valleys (UFVJM and evaluated 60 sweet potato genotypes. For morphological characterization, 24 descriptors were used. For molecular characterization, 11 microsatellite primers specific for sweet potatoes were used, obtaining 210 polymorphic bands. Morphological and molecular diversity was obtained by dissimilarity matrices based on the coefficient of simple matching and the Jaccard index for morphological and molecular data, respectively. From these matrices, dendrograms were built. There is a large amount of genetic variability among sweet potato genotypes of the germplasm bank at UFVJM based on morphological and molecular characterizations. There was no duplicate suspicion or strong association between morphological and molecular analyses. Divergent accessions have been identified by molecular and morphological analyses, which can be used as parents in breeding programmes to produce progenies with high genetic variability.

  9. Design of Skin Penetration Enhancers Using Replacement Methods for the Selection of the Molecular Descriptors

    Directory of Open Access Journals (Sweden)

    Beshoy Abdelmalek

    2012-07-01

    Full Text Available Transdermal delivery of certain drugs is challenging because of skin barrier resistance. This study focuses on the implementation of feature-selection algorithms to design chemical penetration enhancers. A database, consisting of 145 polar and nonpolar chemicals, was chosen for the investigation. Replacement, enhanced replacement and stepwise algorithms were applied to identify relevant structural properties of these compounds. The descriptors were calculated using Molecular Modeling Pro™ Plus. Based on the coefficient of determination, the replacement methods outperformed the stepwise approach in selecting the features that best correlated with the flux enhancement ratio. An artificial neural network model was built to map a subset of descriptors from sixty-one nonpolar enhancers onto the output vector. The R2 value improved from 0.68, for a linear model, to 0.74, which shows that the improved framework might be effective in the design of compounds with user-defined properties.

  10. Descriptor-Based Analysis Applied to HCN Synthesis from NH3 and CH4

    Energy Technology Data Exchange (ETDEWEB)

    Grabow, L

    2011-08-18

    The design of solid metal catalysts using theoretical methods has been a long-standing goal in heterogeneous catalysis. Recent developments in methodology and computer technology as well as the establishment of a descriptor-based approach for the analysis of reaction mechanisms and trends across the periodic table allow for the fast screening for new catalytic materials and have lead to first examples of computational discoveries of new materials. The underlying principles of the descriptor-based approach are the existence of relations between the surface electronic structure, adsorption energies and activation barriers that result in volcano-shaped activity plots as function of simple descriptors, such as atomic binding energies or the d-band center. Linear scaling relations have been established between the adsorption energies of hydrogen-containing molecules such as CH{sub x}, NH{sub x}, OH{sub x} and SH{sub x} and the C, N O and S adsorption energies on transition-metal surfaces. Transition-state energies have also been shown to scale linearly with adsorption energies in a similar fashion. Recently, a single transition state scaling relation has been identified for a large number of C-C, C-O, C-N, N-O, N-N, and O-O coupling reactions. The scaling relations provide a powerful tool for the investigation of reaction mechanisms and the prediction of potential energy surfaces. They limit the number of independent variables to a few, typically adsorption energies of key atoms. Using this information as input to a microkinetic model provides an understanding of trends in catalytic activity across the transition metals. In most cases a volcano-shaped relation between activity and the key variables, the descriptors, is observed. In the present paper we will provide an example of the approach outlined above and show how one can obtain an understanding of activity/selectivity trends of a reaction with just a few new calculations.

  11. Audio Indexing on the Web: a Preliminary Study of Some Audio Descriptors

    OpenAIRE

    Parlangeau-Vallès, Nathalie; Farinas, Jérôme; Fohr, Dominique; Illina, Irina; Magrin-Chagnolleau, Ivan; Mella, Odile; PINQUIER, Julien; Rouas, Jean-Luc; Sénac, Christine

    2003-01-01

    Colloque avec actes et comité de lecture. internationale.; International audience; The "Invisible Web" is composed of documents which can not be currently accessed by Web search engines, because they have a dynamic URL or are not textual, like video or audio documents. For audio documents, one solution is automatic indexing. It consists in finding good descriptors of audio documents which can be used as indexes for archiving and search. This paper presents an overview and recent results of th...

  12. Statistical Descriptors of Ocean Regimes From the Geometric Regularity of SST Observations

    OpenAIRE

    Ba, Sileye O.; Autret, Emmanuelle; Chapron, Bertrand; FABLET, Ronan

    2012-01-01

    In this letter, we evaluate to which extent the activity of ocean fronts can be retrieved from the geometric regularity of ocean tracer observations. Applied to sea surface temperature (SST), we propose a method for the characterization of this geometric regularity from curvature-based statistics along temperature level lines in front regions. To assess the effectiveness of the proposed descriptors, we used six years (from 2003 to 2008) of daily SST observations of the regions of Agulhas in t...

  13. Discretizing LTI Descriptor (Regular Differential Input Systems with Consistent Initial Conditions

    Directory of Open Access Journals (Sweden)

    Athanasios D. Karageorgos

    2010-01-01

    Full Text Available A technique for discretizing efficiently the solution of a Linear descriptor (regular differential input system with consistent initial conditions, and Time-Invariant coefficients (LTI is introduced and fully discussed. Additionally, an upper bound for the error ‖x¯(kT−x¯k‖ that derives from the procedure of discretization is also provided. Practically speaking, we are interested in such kind of systems, since they are inherent in many physical, economical and engineering phenomena.

  14. Enhanced approach to PD control design for linear time-invariant descriptor systems

    Science.gov (United States)

    Filasová, Anna; Krokavec, Dušan

    2017-01-01

    Enhanced approaches to PD controller design, adjusted for linear time-invariant descriptor systems, are proposed in the paper. Presented in the sense of the second Lyapunov method, an associated structure of linear matrix inequalities is outlined to possess the regular closed-loop system dynamic properties. A simulation example, subject to the state and output PD control, demonstrates the effiectiveness of the proposed form of the design technique.

  15. Singular coverings of toposes

    CERN Document Server

    Bunge, Marta

    2006-01-01

    The self-contained theory of certain singular coverings of toposes called complete spreads, that is presented in this volume, is a field of interest to topologists working in knot theory, as well as to various categorists. It extends the complete spreads in topology due to R. H. Fox (1957) but, unlike the classical theory, it emphasizes an unexpected connection with topos distributions in the sense of F. W. Lawvere (1983). The constructions, though often motivated by classical theories, are sometimes quite different from them. Special classes of distributions and of complete spreads, inspired respectively by functional analysis and topology, are studied. Among the former are the probability distributions; the branched coverings are singled out amongst the latter. This volume may also be used as a textbook for an advanced one-year graduate course introducing topos theory with an emphasis on geometric applications. Throughout the authors emphasize open problems. Several routine proofs are left as exercises, but...

  16. On directed coverings

    DEFF Research Database (Denmark)

    Fajstrup, Lisbeth

    In [1], we study coverings in the setting of directed topology. Unfortunately, there is a condition missing in the definition of a directed covering. Some of the results in [1] require this extra condition and in fact it was claimed to follow from the original definition. It is the purpose...... of this note to give the right definition and point out how this affects the statements in that paper. Moreover, we give an example of a dicovering in the sense of [1], which does not satisfy the extra condition. Fortunately, with the extra condition, the subsequent results are now correct. [1] L. Fajstrup......, Dicovering spaces, Homology Homotopy Appl. 5 (2003), no. 2, 1-17....

  17. PERFORMANCE EVALUATION OF DISTANCE MEASURES IN PROPOSED FUZZY TEXTURE MODEL FOR LAND COVER CLASSIFICATION OF REMOTELY SENSED IMAGE

    Directory of Open Access Journals (Sweden)

    S. Jenicka

    2014-04-01

    Full Text Available Land cover classification is a vital application area in satellite image processing domain. Texture is a useful feature in land cover classification. The classification accuracy obtained always depends on the effectiveness of the texture model, distance measure and classification algorithm used. In this work, texture features are extracted using the proposed multivariate descriptor, MFTM/MVAR that uses Multivariate Fuzzy Texture Model (MFTM supplemented with Multivariate Variance (MVAR. The K_Nearest Neighbour (KNN algorithm is used for classification due to its simplicity coupled with efficiency. The distance measures such as Log likelihood, Manhattan, Chi squared, Kullback Leibler and Bhattacharyya were used and the experiments were conducted on IRS P6 LISS-IV data. The classified images were evaluated based on error matrix, classification accuracy and Kappa statistics. From the experiments, it is found that log likelihood distance with MFTM/MVAR descriptor and KNN classifier gives 95.29% classification accuracy.

  18. Structural descriptor database: a new tool for sequence-based functional site prediction

    Directory of Open Access Journals (Sweden)

    Vasconcelos Ana

    2008-11-01

    Full Text Available Abstract Background The Structural Descriptor Database (SDDB is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties of related protein families. Structural alignments and functional residues of a known protein set (defined as the training set are used to build special Hidden Markov Models (HMM called HMM descriptors. SDDB uses previously calculated and stored HMM descriptors for predicting active sites, binding residues, and protein function. The database integrates biologically relevant data filtered from several databases such as PDB, PDBSUM, CSA and SCOP. It accepts queries in fasta format and predicts functional residue positions, protein-ligand interactions, and protein function, based on the SCOP database. Results To assess the SDDB performance, we used different data sets. The Trypsion-like Serine protease data set assessed how well SDDB predicts functional sites when curated data is available. The SCOP family data set was used to analyze SDDB performance by using training data extracted from PDBSUM (binding sites and from CSA (active sites. The ATP-binding experiment was used to compare our approach with the most current method. For all evaluations, significant improvements were obtained with SDDB. Conclusion SDDB performed better when trusty training data was available. SDDB worked better in predicting active sites rather than binding sites because the former are more conserved than the latter. Nevertheless, by using our prediction method we obtained results with precision above 70%.

  19. Modeling the depuration rates of polychlorinated biphenyls in two mussel species with theoretical molecular descriptors

    Institute of Scientific and Technical Information of China (English)

    XU MingZhu; LIU XinHui; WANG Liang; WU Dan; SUN Tao; YANG ZhiFeng; CUI BaoShan

    2009-01-01

    Using theoretical molecular descriptors as well as partial least squares (PLS) regression,two quantitative structure-activity relationship (QSAR) models were developed for depuration rate constants (kd) of polychlorinated biphenyls (PCBs) in two species of mussels,Perna viridis and Dreissena polymorpha.Thecross-validated Q2cum (an indicator of fitting of goodness) values for the two models are 0.501 and 0.756,and the standard deviation (SO) is 0.084 and 0.076,respectively.The achievement of satisfactory Q2cumand low SD values indicates good predictive ability and precision of the two models.The significant descriptors governing Igkd include polarizability (a),molecular volume (/Mv),molecular weight (Mw),molecular surface area (S),and total energy (TE).The key descriptors in the models reflect that van der Waals interactions play a dominant role in the depuration of PCBs.The depuration of PCBs in the two mussel species may be mainly attributed to the biota-water phase partitioning processes.

  20. The development of a comprehensive headache diary--verbal descriptor scales.

    Science.gov (United States)

    Anciano, D

    1987-09-01

    A headache diary was developed to allow the ongoing assessment of subjective and behavioural components of headache pain. A modified version of Philips & Hunter's (1981) pain behaviour checklist which assesses three types of pain behaviour was incorporated for the latter. A scale based on pain descriptors was developed for the subjective component. This scale was factor analysed to reveal five aspects of headache pain, two reactive and three sensory. When the descriptors were scaled it was found that the amount of pain represented by some words was significantly greater in headache than non-headache subjects. Within each descriptor factor, the words do not appear to vary in intensity, with the exception of one reactive factor which appears to reflect overall evaluation of pain. Internal validity of the diary was investigated showing distinctive patterns of association between the subjective factors, pain behaviour, and pain intensity. External validity was assessed by the use of the diary in an intervention study and in delineating differences between migraine and tension headache groups.

  1. Application of quantum descriptors for predicting adsorption performance of starch and cyclodextrin adsorbents.

    Science.gov (United States)

    Okoli, Chukwunonso Peter; Guo, Qing Jun; Adewuyi, Gregory Olufemi

    2014-01-30

    Adsorption trend of aromatic compounds on epichlorohydrin (EPI), 1,6-hexamethylene diisocyanate (HDI), and 4,4-methylene diphenyl diisocyanate (MDI) cross-linked starch and cyclodextrin adsorbents were comparatively studied by density functional theorem (DFT) based interaction descriptors and batch adsorption studies. The DFT quantum chemical descriptors predicted adsorption trend of MDI adsorbents>HDI adsorbents>EPI adsorbents. The values of the fractional number of electrons transferred (ΔN) for all the studied adsorbent-adsorbate pair were negative, indicating that the adsorbents were electron donors in the studied adsorption interaction. The batch adsorption performance for the studied cross-linked adsorbents was in agreement with the DFT predictions. Energy gap, chemical hardness, and softness showed good linear correlation (R(2)=0.8,073 ± 0.2259) to the batch adsorption performance for most of the studied adsorbent-adsorbate pairs. The present study demonstrated that DFT quantum chemical parameters are suitable adsorption descriptors for predicting adsorption performance of cross-linked adsorbents. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Modeling the depuration rates of polychlorinated biphenyls in two mussel species with theoretical molecular descriptors

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Using theoretical molecular descriptors as well as partial least squares(PLS) regression,two quantitative structure-activity relationship(QSAR) models were developed for depuration rate constants(kd) of polychlorinated biphenyls(PCBs) in two species of mussels,Perna viridis and Dreissena polymorpha.The cross-validated Q2cum(an indicator of fitting of goodness) values for the two models are 0.501 and 0.756,and the standard deviation(SD) is 0.084 and 0.076,respectively.The achievement of satisfactory Q2cum and low SD values indicates good predictive ability and precision of the two models.The significant descriptors governing lgkd include polarizability(α),molecular volume(MV),molecular weight(Mw),molecular surface area(S),and total energy(TE).The key descriptors in the models reflect that van der Waals interactions play a dominant role in the depuration of PCBs.The depuration of PCBs in the two mussel species may be mainly attributed to the biota-water phase partitioning processes.

  3. Edge-SIFT: discriminative binary descriptor for scalable partial-duplicate mobile search.

    Science.gov (United States)

    Zhang, Shiliang; Tian, Qi; Lu, Ke; Huang, Qingming; Gao, Wen

    2013-07-01

    As the basis of large-scale partial duplicate visual search on mobile devices, image local descriptor is expected to be discriminative, efficient, and compact. Our study shows that the popularly used histogram-based descriptors, such as scale invariant feature transform (SIFT) are not optimal for this task. This is mainly because histogram representation is relatively expensive to compute on mobile platforms and loses significant spatial clues, which are important for improving discriminative power and matching near-duplicate image patches. To address these issues, we propose to extract a novel binary local descriptor named Edge-SIFT from the binary edge maps of scale- and orientation-normalized image patches. By preserving both locations and orientations of edges and compressing the sparse binary edge maps with a boosting strategy, the final Edge-SIFT shows strong discriminative power with compact representation. Furthermore, we propose a fast similarity measurement and an indexing framework with flexible online verification. Hence, the Edge-SIFT allows an accurate and efficient image search and is ideal for computation sensitive scenarios such as a mobile image search. Experiments on a large-scale dataset manifest that the Edge-SIFT shows superior retrieval accuracy to Oriented BRIEF (ORB) and is superior to SIFT in the aspects of retrieval precision, efficiency, compactness, and transmission cost.

  4. Cations in Octahedral Sites: A Descriptor for Oxygen Electrocatalysis on Transition-Metal Spinels

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Chao; Feng, Zhenxing; Scherer, Günther G.; Barber, James; Shao-Horn, Yang; Xu, Zhichuan J. (Nanyang); (ICL); (Oregon State U.); (TUM-CREATE); (MIT)

    2017-04-10

    Exploring efficient and low-cost electrocatalysts for the oxygen-reduction reaction (ORR) and oxygen-evolution reaction (OER) is critical for developing renewable energy technologies such as fuel cells, metal–air batteries, and water electrolyzers. A rational design of a catalyst can be guided by identifying descriptors that determine its activity. Here, a descriptor study on the ORR/OER of spinel oxides is presented. With a series of MnCo2O4, the Mn in octahedral sites is identified as an active site. This finding is then applied to successfully explain the ORR/OER activities of other transition-metal spinels, including MnxCo3-xO4 (x = 2, 2.5, 3), LixMn2O4 (x = 0.7, 1), XCo2O4 (X = Co, Ni, Zn), and XFe2O4 (X = Mn, Co, Ni). A general principle is concluded that the eg occupancy of the active cation in the octahedral site is the activity descriptor for the ORR/OER of spinels, consolidating the role of electron orbital filling in metal oxide catalysis.

  5. A novel 3D shape descriptor for automatic retrieval of anatomical structures from medical images

    Science.gov (United States)

    Nunes, Fátima L. S.; Bergamasco, Leila C. C.; Delmondes, Pedro H.; Valverde, Miguel A. G.; Jackowski, Marcel P.

    2017-03-01

    Content-based image retrieval (CBIR) aims at retrieving from a database objects that are similar to an object provided by a query, by taking into consideration a set of extracted features. While CBIR has been widely applied in the two-dimensional image domain, the retrieval of3D objects from medical image datasets using CBIR remains to be explored. In this context, the development of descriptors that can capture information specific to organs or structures is desirable. In this work, we focus on the retrieval of two anatomical structures commonly imaged by Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) techniques, the left ventricle of the heart and blood vessels. Towards this aim, we developed the Area-Distance Local Descriptor (ADLD), a novel 3D local shape descriptor that employs mesh geometry information, namely facet area and distance from centroid to surface, to identify shape changes. Because ADLD only considers surface meshes extracted from volumetric medical images, it substantially diminishes the amount of data to be analyzed. A 90% precision rate was obtained when retrieving both convex (left ventricle) and non-convex structures (blood vessels), allowing for detection of abnormalities associated with changes in shape. Thus, ADLD has the potential to aid in the diagnosis of a wide range of vascular and cardiac diseases.

  6. BENCHMARK EVALUATION OF HOG DESCRIPTORS AS FEATURES FOR CLASSIFICATION OF TRAFFIC SIGNS

    Directory of Open Access Journals (Sweden)

    Hasan Fleyeh

    2013-12-01

    Full Text Available The purpose of this paper is to analyze the performance of the Histograms of Oriented Gradients (HOG as descriptors for traffic signs recognition. The test dataset consists of speed limit traffic signs because of their high inter-class similarities. HOG features of speed limit signs, which were extracted from different traffic scenes, were computed and a Gentle AdaBoost classifier was invoked to evaluate the different features. The performance of HOG was tested with a dataset consisting of 1727 Swedish speed signs images. Different numbers of HOG features per descriptor, ranging from 36 features up 396 features, were computed for each traffic sign in the benchmark testing. The results show that HOG features perform high classification rate as the Gentle AdaBoost classification rate was 99.42%, and they are suitable to real time traffic sign recognition. However, it is found that changing the number of orientation bins has insignificant effect on the classification rate. In addition to this, HOG descriptors are not robust with respect to sign orientation.

  7. Thermodynamics of organic chemical hydration: QSPR models using physicochemical HYBOT descriptors.

    Science.gov (United States)

    Raevsky, O A; Liplavskiy, Y V; Raevskaya, O E; Mannhold, R

    2009-07-01

    Stable and predictive quantitative structure-property relationship (QSPR) models of thermodynamics of chemical hydration (changes in Gibbs energy, DeltaG(air/water), enthalpy, DeltaH(air/water) and entropy DeltaS(air/water)) were obtained on the basis of physicochemical descriptors calculated by the HYBOT program. The structurally diverse training set (n = 151) and test set (n = 37) included 13 mono-functional chemical classes. The applied HYBOT descriptors comprise molecular polarizability alpha (as a volume-related term), the sum of partial negative charges on all atoms in a molecule SigmaQ(-) (as an electrostatic term) and the sum of H-bond acceptor and donor factors SigmaC(a) and SigmaC(d) (as H-bond terms). Final equations for changes in Gibbs energy and enthalpy provided good statistical criteria and standard deviations on the level of errors of experimental determinations. All four above-mentioned terms essentially contribute to hydration enthalpy and each of them increases negative values of enthalpy. Hydration Gibbs energy predominantly depends on hydrogen bonding between solute and water molecules. Steric and electrostatic terms act in opposite directions and partly compensate each other. Changes in entropy correlate with increasing H-bond acceptor ability, whereas the other three descriptors exhibit inverse correlations.

  8. Distinctive Order Based Self-Similarity descriptor for multi-sensor remote sensing image matching

    Science.gov (United States)

    Sedaghat, Amin; Ebadi, Hamid

    2015-10-01

    Robust, well-distributed and accurate feature matching in multi-sensor remote sensing image is a difficult task duo to significant geometric and illumination differences. In this paper, a robust and effective image matching approach is presented for multi-sensor remote sensing images. The proposed approach consists of three main steps. In the first step, UR-SIFT (Uniform robust scale invariant feature transform) algorithm is applied for uniform and dense local feature extraction. In the second step, a novel descriptor namely Distinctive Order Based Self Similarity descriptor, DOBSS descriptor, is computed for each extracted feature. Finally, a cross matching process followed by a consistency check in the projective transformation model is performed for feature correspondence and mismatch elimination. The proposed method was successfully applied for matching various multi-sensor satellite images as: ETM+, SPOT 4, SPOT 5, ASTER, IRS, SPOT 6, QuickBird, GeoEye and Worldview sensors, and the results demonstrate its robustness and capability compared to common image matching techniques such as SIFT, PIIFD, GLOH, LIOP and LSS.

  9. Performance of Global-Appearance Descriptors in Map Building and Localization Using Omnidirectional Vision

    Directory of Open Access Journals (Sweden)

    Luis Payá

    2014-02-01

    Full Text Available Map building and localization are two crucial abilities that autonomous robots must develop. Vision sensors have become a widespread option to solve these problems. When using this kind of sensors, the robot must extract the necessary information from the scenes to build a representation of the environment where it has to move and to estimate its position and orientation with robustness. The techniques based on the global appearance of the scenes constitute one of the possible approaches to extract this information. They consist in representing each scene using only one descriptor which gathers global information from the scene. These techniques present some advantages comparing to other classical descriptors, based on the extraction of local features. However, it is important a good configuration of the parameters to reach a compromise between computational cost and accuracy. In this paper we make an exhaustive comparison among some global appearance descriptors to solve the mapping and localization problem. With this aim, we make use of several image sets captured in indoor environments under realistic working conditions. The datasets have been collected using an omnidirectional vision sensor mounted on the robot.

  10. Estimating VDT Mental Fatigue Using Multichannel Linear Descriptors and KPCA-HMM

    Directory of Open Access Journals (Sweden)

    Yi Ouyang

    2008-04-01

    Full Text Available The impacts of prolonged visual display terminal (VDT work on central nervous system and autonomic nervous system are observed and analyzed based on electroencephalogram (EEG and heart rate variability (HRV. Power spectral indices of HRV, the P300 components based on visual oddball task, and multichannel linear descriptors of EEG are combined to estimate the change of mental fatigue. The results show that long-term VDT work induces the mental fatigue. The power spectral of HRV, the P300 components, and multichannel linear descriptors of EEG are correlated with mental fatigue level. The cognitive information processing would come down after long-term VDT work. Moreover, the multichannel linear descriptors of EEG can effectively reflect the changes of θ, α, and β waves and may be used as the indices of the mental fatigue level. The kernel principal component analysis (KPCA and hidden Markov model (HMM are combined to differentiate two mental fatigue states. The investigation suggests that the joint KPCA-HMM method can effectively reduce the dimensions of the feature vectors, accelerate the classification speed, and improve the accuracy of mental fatigue to achieve the maximum 88%. Hence KPCA-HMM could be a promising model for the estimation of mental fatigue.

  11. Estimating VDT Mental Fatigue Using Multichannel Linear Descriptors and KPCA-HMM

    Science.gov (United States)

    Zhang, Chong; Zheng, Chongxun; Yu, Xiaolin; Ouyang, Yi

    2008-12-01

    The impacts of prolonged visual display terminal (VDT) work on central nervous system and autonomic nervous system are observed and analyzed based on electroencephalogram (EEG) and heart rate variability (HRV). Power spectral indices of HRV, the P300 components based on visual oddball task, and multichannel linear descriptors of EEG are combined to estimate the change of mental fatigue. The results show that long-term VDT work induces the mental fatigue. The power spectral of HRV, the P300 components, and multichannel linear descriptors of EEG are correlated with mental fatigue level. The cognitive information processing would come down after long-term VDT work. Moreover, the multichannel linear descriptors of EEG can effectively reflect the changes of θ, α, and β waves and may be used as the indices of the mental fatigue level. The kernel principal component analysis (KPCA) and hidden Markov model (HMM) are combined to differentiate two mental fatigue states. The investigation suggests that the joint KPCA-HMM method can effectively reduce the dimensions of the feature vectors, accelerate the classification speed, and improve the accuracy of mental fatigue to achieve the maximum 88%. Hence KPCA-HMM could be a promising model for the estimation of mental fatigue.

  12. A novel method for protein-ligand binding affinity prediction and the related descriptors exploration.

    Science.gov (United States)

    Li, Shuyan; Xi, Lili; Wang, Chengqi; Li, Jiazhong; Lei, Beilei; Liu, Huanxiang; Yao, Xiaojun

    2009-04-30

    In this study, a novel method was developed to predict the binding affinity of protein-ligand based on a comprehensive set of structurally diverse protein-ligand complexes (PLCs). The 1300 PLCs with binding affinity (493 complexes with K(d) and 807 complexes with K(i)) from the refined dataset of PDBbind Database (release 2007) were studied in the predictive model development. In this method, each complex was described using calculated descriptors from three blocks: protein sequence, ligand structure, and binding pocket. Thereafter, the PLCs data were rationally split into representative training and test sets by full consideration of the validation of the models. The molecular descriptors relevant to the binding affinity were selected using the ReliefF method combined with least squares support vector machines (LS-SVMs) modeling method based on the training data set. Two final optimized LS-SVMs models were developed using the selected descriptors to predict the binding affinities of K(d) and K(i). The correlation coefficients (R) of training set and test set for K(d) model were 0.890 and 0.833. The corresponding correlation coefficients for the K(i) model were 0.922 and 0.742, respectively. The prediction method proposed in this work can give better generalization ability than other recently published methods and can be used as an alternative fast filter in the virtual screening of large chemical database. (c) 2008 Wiley Periodicals, Inc.

  13. Covering R-trees

    CERN Document Server

    Berestovskii, V N

    2007-01-01

    We show that every inner metric space X is the metric quotient of a complete R-tree via a free isometric action, which we call the covering R-tree of X. The quotient mapping is a weak submetry (hence, open) and light. In the case of compact 1-dimensional geodesic space X, the free isometric action is via a subgroup of the fundamental group of X. In particular, the Sierpin'ski gasket and carpet, and the Menger sponge all have the same covering R-tree, which is complete and has at each point valency equal to the continuum. This latter R-tree is of particular interest because it is "universal" in at least two senses: First, every R-tree of valency at most the continuum can be isometrically embedded in it. Second, every Peano continuum is the image of it via an open light mapping. We provide a sketch of our previous construction of the uniform universal cover in the special case of inner metric spaces, the properties of which are used in the proof.

  14. Pointwise completeness and pointwise degeneracy of positive fractional descriptor continuous-time linear systems with regular pencils

    Directory of Open Access Journals (Sweden)

    Kaczorek Tadeusz

    2015-06-01

    Full Text Available Pointwise completeness and pointwise degeneracy of positive fractional descriptor continuous-time linear systems with regular pencils are addressed. Conditions for pointwise completeness and pointwise degeneracy of the systems are established and illustrated by an example.

  15. Minimum energy control of descriptor discrete-time linear systems by the use of Weierstrass-Kronecker decomposition

    Directory of Open Access Journals (Sweden)

    Kaczorek Tadeusz

    2016-06-01

    Full Text Available The minimum energy control problem for the descriptor discrete-time linear systems by the use of Weierstrass-Kronecker decomposition is formulated and solved. Necessary and sufficient conditions for the reachability of descriptor discrete-time linear systems are given. A procedure for computation of optimal input and a minimal value of the performance index is proposed and illustrated by a numerical example.

  16. Breast Imaging Reporting and Data System (BI-RADS) breast composition descriptors: Automated measurement development for full field digital mammography

    OpenAIRE

    Fowler, E. E.; Sellers, T.A.; Lu, B.; Heine, J.J.

    2013-01-01

    Purpose: The Breast Imaging Reporting and Data System (BI-RADS) breast composition descriptors are used for standardized mammographic reporting and are assessed visually. This reporting is clinically relevant because breast composition can impact mammographic sensitivity and is a breast cancer risk factor. New techniques are presented and evaluated for generating automated BI-RADS breast composition descriptors using both raw and calibrated full field digital mammography (FFDM) image data.

  17. A quantitative structure–activity relationship (QSAR) study of peptide drugs based on a new descriptor of amino acids

    OpenAIRE

    Tong Jian-Bo; Chang Jia; Liu Shu-Ling; Bai Min

    2015-01-01

    Quantitative structure-activity relationships (QSAR) approach is used for finding the relationship between molecular structures and the activity of peptide drugs. In this work, stepwise multiple regression, was employed to select optimal subset of descriptors that have significant contribution to the drug activity of 21 oxytocin analogues, 48 bitter tasting threshold, and 58 angiotensin-converting enzyme inhibitors. A new set of descriptor, SVWGM, was used ...

  18. Application of two methods of calculation of solvation descriptor L to estimate C5 -C7 alkenes retention.

    Science.gov (United States)

    Jirkal, Štěpán; Ševčík, Jiří G K

    2015-07-01

    The solvation descriptor L for 59 isomers of all C5 -C7 alkenes was calculated using two methods based on additive contributions of particular fragments in the molecule by the method of Havelec and Ševčík and the method of Platts and Butina. These descriptors were used to estimate the gas chromatography retention of alkenes on squalane and polydimethylsiloxane stationary phases. The retention was described better by the Platts-Butina method. Modification of the Havelec-Ševčík method by omitting the contribution for interaction of the cis isomers led to a substantial improvement in the estimation ability of the model. The modified Havelec-Ševčík method was found to be preferable for estimation of the descriptor L compared to the Platts-Butina method. A more comprehensive description of the retention of alkenes was achieved by inclusion of an additional descriptor E. This model with the descriptors L and E yielded better estimation for alkenes compared to the model with a single descriptor.

  19. Using probabilistic model as feature descriptor on a smartphone device for autonomous navigation of unmanned ground vehicles

    Science.gov (United States)

    Desai, Alok; Lee, Dah-Jye

    2013-12-01

    There has been significant research on the development of feature descriptors in the past few years. Most of them do not emphasize real-time applications. This paper presents the development of an affine invariant feature descriptor for low resource applications such as UAV and UGV that are equipped with an embedded system with a small microprocessor, a field programmable gate array (FPGA), or a smart phone device. UAV and UGV have proven suitable for many promising applications such as unknown environment exploration, search and rescue operations. These applications required on board image processing for obstacle detection, avoidance and navigation. All these real-time vision applications require a camera to grab images and match features using a feature descriptor. A good feature descriptor will uniquely describe a feature point thus allowing it to be correctly identified and matched with its corresponding feature point in another image. A few feature description algorithms are available for a resource limited system. They either require too much of the device's resource or too much simplification on the algorithm, which results in reduction in performance. This research is aimed at meeting the needs of these systems without sacrificing accuracy. This paper introduces a new feature descriptor called PRObabilistic model (PRO) for UGV navigation applications. It is a compact and efficient binary descriptor that is hardware-friendly and easy for implementation.

  20. Covered Clause Elimination

    CERN Document Server

    Heule, Marijn; Biere, Armin

    2010-01-01

    Generalizing the novel clause elimination procedures developed in [M. Heule, M. J\\"arvisalo, and A. Biere. Clause elimination procedures for CNF formulas. In Proc. LPAR-17, volume 6397 of LNCS, pages 357-371. Springer, 2010.], we introduce explicit (CCE), hidden (HCCE), and asymmetric (ACCE) variants of a procedure that eliminates covered clauses from CNF formulas. We show that these procedures are more effective in reducing CNF formulas than the respective variants of blocked clause elimination, and may hence be interesting as new preprocessing/simplification techniques for SAT solving.

  1. Robust stabilization of linear descriptor systems. Quadratic stabilization approach of equivalent systems; Descriptor system no robust anteika. Toka system ni taisuru 2 ji anteika kara no approach

    Energy Technology Data Exchange (ETDEWEB)

    Uezato, E. [Ryukyu Univ., Nishihara, Okinawa (Japan)] Ikeda, M. [Osaka Univ., Suita (Japan)] Toyama, R. [Kobe Univ. (Japan)

    1998-11-30

    This paper presents two sufficient conditions as linear and bilinear matrix conditions for a system with polytopic uncertainties to be robustly stabilizable by an approach of quadratic stabilization of equivalent systems as regards closed system and robust stabilization. For the purpose, two systems are assumed which are equivalent concerning closed loop system and robust stabilization and contains no uncertainty in the coefficient matrix of the differential of descriptor variables. The robust stability conditions for the original system are obtained by deriving quadratic stabilization conditions of the equivalent systems because the original closed system is robustly stable if those equivalent systems are quadratically stable. Robust stabilizability conditions for a system with polytopic uncertainties in the coefficient matrix are given in terms of linear and bilinear matrix inequalities. In addition, an algorithm based on the idea of the homotopy method is proposed to solve the bilinear matrix inequality. 13 refs., 1 fig.

  2. Cover Lines Using Positive, Urgent, Unique Language Entice Moms to Read Health Communications.

    Science.gov (United States)

    Martin-Biggers, Jennifer; Beluska, Katrina; Quick, Virginia; Tursi, Mary; Byrd-Bredbenner, Carol

    2015-01-01

    Crafting messages that capture consumer interest is a frequent challenge of health communicators. A better understanding of the techniques magazine editors use to create cover lines may aid health communicators in their efforts to arouse interest in their communiqués. This study (a) content-analyzed magazine cover lines, (b) used content analysis findings to create health-related cover lines, and (c) assessed the degree to which the health-related cover lines fostered motivation to read the health communication. Cover lines (N = 867) from 11 magazines published in 2012 frequently read by mothers of young children used a variety of themes, with those focusing on informative/how-to, control/improve, and unique/special being most common. Health communication experts used key descriptor terms corresponding to each theme and wrote 310 cover lines for topics focusing on childhood obesity prevention strategies. Unpaired t tests revealed that mothers of young children (N = 77) reported they were significantly (p health-related magazine article when cover lines had a happiness/fun, unique/special, or quick/urgency theme and were significantly less motivated to read when cover lines used a control/improve theme. Study findings may help health communicators create cover lines that better attract reader attention.

  3. Covering walks in graphs

    CERN Document Server

    Fujie, Futaba

    2014-01-01

    Covering Walks  in Graphs is aimed at researchers and graduate students in the graph theory community and provides a comprehensive treatment on measures of two well studied graphical properties, namely Hamiltonicity and traversability in graphs. This text looks into the famous Kӧnigsberg Bridge Problem, the Chinese Postman Problem, the Icosian Game and the Traveling Salesman Problem as well as well-known mathematicians who were involved in these problems. The concepts of different spanning walks with examples and present classical results on Hamiltonian numbers and upper Hamiltonian numbers of graphs are described; in some cases, the authors provide proofs of these results to illustrate the beauty and complexity of this area of research. Two new concepts of traceable numbers of graphs and traceable numbers of vertices of a graph which were inspired by and closely related to Hamiltonian numbers are introduced. Results are illustrated on these two concepts and the relationship between traceable concepts and...

  4. Land Use and Land Cover - Montana Land Cover Framework 2013

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This statewide land cover theme is a baseline digital map of Montana's natural and human land cover. The baseline map is adapted from the Northwest ReGAP project...

  5. Toward a No-Reference Image Quality Assessment Using Statistics of Perceptual Color Descriptors.

    Science.gov (United States)

    Lee, Dohyoung; Plataniotis, Konstantinos N

    2016-08-01

    Analysis of the statistical properties of natural images has played a vital role in the design of no-reference (NR) image quality assessment (IQA) techniques. In this paper, we propose parametric models describing the general characteristics of chromatic data in natural images. They provide informative cues for quantifying visual discomfort caused by the presence of chromatic image distortions. The established models capture the correlation of chromatic data between spatially adjacent pixels by means of color invariance descriptors. The use of color invariance descriptors is inspired by their relevance to visual perception, since they provide less sensitive descriptions of image scenes against viewing geometry and illumination variations than luminances. In order to approximate the visual quality perception of chromatic distortions, we devise four parametric models derived from invariance descriptors representing independent aspects of color perception: 1) hue; 2) saturation; 3) opponent angle; and 4) spherical angle. The practical utility of the proposed models is examined by deploying them in our new general-purpose NR IQA metric. The metric initially estimates the parameters of the proposed chromatic models from an input image to constitute a collection of quality-aware features (QAF). Thereafter, a machine learning technique is applied to predict visual quality given a set of extracted QAFs. Experimentation performed on large-scale image databases demonstrates that the proposed metric correlates well with the provided subjective ratings of image quality over commonly encountered achromatic and chromatic distortions, indicating that it can be deployed on a wide variety of color image processing problems as a generalized IQA solution.

  6. Estimation of the volume of distribution of some pharmacologically important compounds from their structural descriptor

    Directory of Open Access Journals (Sweden)

    MOHAMMAD H. FATEMI

    2011-07-01

    Full Text Available Quantitative structure–activity relationship (QSAR approaches were used to estimate the volume of distribution (Vd using an artificial neural network (ANN. The data set consisted of the volume of distribution of 129 pharmacologically important compounds, i.e., benzodiazepines, barbiturates, nonsteroidal anti-inflammatory drugs (NSAIDs, tricyclic anti-depressants and some antibiotics, such as betalactams, tetracyclines and quinolones. The descriptors, which were selected by stepwise variable selection methods, were: the Moriguchi octanol–water partition coefficient; the 3D-MoRSE-signal 30, weighted by atomic van der Waals volumes; the fragment-based polar surface area; the d COMMA2 value, weighted by atomic masses; the Geary autocorrelation, weighted by the atomic Sanderson electronegativities; the 3D-MoRSE – signal 02, weighted by atomic masses, and the Geary autocorrelation – lag 5, weighted by the atomic van der Waals volumes. These descriptors were used as inputs for developing multiple linear regressions (MLR and artificial neural network models as linear and non-linear feature mapping techniques, respectively. The standard errors in the estimation of Vd by the MLR model were: 0.104, 0.103 and 0.076 and for the ANN model: 0.029, 0.087 and 0.082 for the training, internal and external validation test, respectively. The robustness of these models were also evaluated by the leave-5-out cross validation procedure, that gives the statistics Q2 = 0.72 for the MLR model and Q2 = 0.82 for the ANN model. Moreover, the results of the Y-randomization test revealed that there were no chance correlations among the data matrix. In conclusion, the results of this study indicate the applicability of the estimation of the Vd value of drugs from their structural molecular descriptors. Furthermore, the statistics of the developed models indicate the superiority of the ANN over the MLR model.

  7. The Correlation between Readability and Circulation in Regard to the Twenty-Six Daily Newspapers of New Jersey.

    Science.gov (United States)

    Cottler, Risa

    A study examined 20 New Jersey daily newspapers to assess the impact of readability on circulation. It was hypothesized that the circulation of a newspaper would be inversely related to the readability level of its contents; that is to say, as reading material becomes harder to read, fewer people will read it. News pieces (divided into hard news,…

  8. Widening educational disparities in premature death rates in twenty six states in the United States, 1993-2007.

    Directory of Open Access Journals (Sweden)

    Jiemin Ma

    Full Text Available BACKGROUND: Eliminating socioeconomic disparities in health is an overarching goal of the U.S. Healthy People decennial initiatives. We present recent trends in mortality by education among working-aged populations. METHODS AND FINDINGS: Age-standardized death rates and their average annual percent change for all-cause and five major causes (cancer, heart disease, stroke, diabetes, and accidents were calculated from 1993 through 2007 for individuals aged 25-64 years by educational attainment as a marker of socioeconomic status, using national vital registration data for 26 states with consistent educational information on the death certificates. Rate ratios and rate differences were used to assess disparities (≤12 versus ≥16 years of education for 1993 through 2007. From 1993 through 2007, relative educational disparities in all-cause mortality continued to increase among working-aged men and women in the U.S., due to larger decreases of mortality rates among the most educated coupled with smaller decreases or even worsening trends in the less educated. For example, the rate ratios of all-cause mortality increased from 2.5 (95% confidence interval (CI, 2.4-2.6 in 1993 to 3.6 (95% CI, 3.5-3.7 in 2007 in men and from 1.9 (95% CI, 1.8-2.0 to 3.0 (95% CI, 2.9-3.1 in women. Generally, the rate differences (per 100,000 persons of all-cause mortality increased from 415.5 (95% CI, 399.1-431.9 in 1993 to 472.7 (95% CI, 460.2-485.2 in 2007 in men and from 165.4 (95% CI, 154.5-176.2 to 256.2 (95% CI, 248.3-264.2 in women. Disparity patterns varied largely across the five specific causes considered in this study, with the largest increases of relative disparities for accidents, especially in women. CONCLUSIONS: Relative educational differentials in mortality continued to widen among men and women despite emphasis on reducing disparities in the U.S. Healthy People decennial initiatives.

  9. Widening educational disparities in premature death rates in twenty six states in the United States, 1993-2007.

    Science.gov (United States)

    Ma, Jiemin; Xu, Jiaquan; Anderson, Robert N; Jemal, Ahmedin

    2012-01-01

    Eliminating socioeconomic disparities in health is an overarching goal of the U.S. Healthy People decennial initiatives. We present recent trends in mortality by education among working-aged populations. Age-standardized death rates and their average annual percent change for all-cause and five major causes (cancer, heart disease, stroke, diabetes, and accidents) were calculated from 1993 through 2007 for individuals aged 25-64 years by educational attainment as a marker of socioeconomic status, using national vital registration data for 26 states with consistent educational information on the death certificates. Rate ratios and rate differences were used to assess disparities (≤12 versus ≥16 years of education) for 1993 through 2007. From 1993 through 2007, relative educational disparities in all-cause mortality continued to increase among working-aged men and women in the U.S., due to larger decreases of mortality rates among the most educated coupled with smaller decreases or even worsening trends in the less educated. For example, the rate ratios of all-cause mortality increased from 2.5 (95% confidence interval (CI), 2.4-2.6) in 1993 to 3.6 (95% CI, 3.5-3.7) in 2007 in men and from 1.9 (95% CI, 1.8-2.0) to 3.0 (95% CI, 2.9-3.1) in women. Generally, the rate differences (per 100,000 persons) of all-cause mortality increased from 415.5 (95% CI, 399.1-431.9) in 1993 to 472.7 (95% CI, 460.2-485.2) in 2007 in men and from 165.4 (95% CI, 154.5-176.2) to 256.2 (95% CI, 248.3-264.2) in women. Disparity patterns varied largely across the five specific causes considered in this study, with the largest increases of relative disparities for accidents, especially in women. Relative educational differentials in mortality continued to widen among men and women despite emphasis on reducing disparities in the U.S. Healthy People decennial initiatives.

  10. Review of medical findings in a Marshallese population twenty-six years after accidental exposure to radioactive fallout

    Energy Technology Data Exchange (ETDEWEB)

    Conard, R.A.; Paglia, D.E.; Larsen, P.R.

    1980-01-01

    In March 1954, radioactive debris from a thermonuclear weapon test at Bikini Atoll deviated from predicted trajectories and contaminated several atolls in the northern Marshall Islands. As a result, 239 native inhabitants of these islands along with 28 American servicemen and 23 Japanese fishermen received variably severe exposures to diverse ionizing radiations. Fallout material consisted largely of mixed fission products with small amounts of neutron-induced radionuclides and minimal amounts of fissionable elements, producing a complex spectrum of electromagnetic and particulate radiation. Individuals were exposed to deeply penetrating, whole-body gamma irradiation, to internal radiation emitters assimilated either by inhalation or by ingestion of contaminated water and food, and to direct radiation from material accumulating on body surfaces. That accident initiated a cascade of events, medical, social and political, which continue in varying forms to this day. Most of these have been discussed in the open medical literature and in periodic reports issued by the medical team headquartered at Brookhaven National Laboratory. This report attempts to summarize some of the principal findings of medical significnce that have been observed during the subsequent 26 years with particular emphasis on the last six years.

  11. Anti-oxidant activity and major chemical component analyses of twenty-six commercially available essential oils.

    Science.gov (United States)

    Wang, Hsiao-Fen; Yih, Kuang-Hway; Yang, Chao-Hsun; Huang, Keh-Feng

    2017-10-01

    This study analyzed 26 commercially available essential oils and their major chemical components to determine their antioxidant activity levels by measuring their total phenolic content (TPC), reducing power (RP), β-carotene bleaching (BCB) activity, trolox equivalent antioxidant capacity (TEAC), and 1,1-diphenyl-2-picrylhydrazyl free radical scavenging (DFRS) ability. The clove bud and thyme borneol essential oils had the highest RP, BCB activity levels, and TPC values among the 26 commercial essential oils. Furthermore, of the 26 essential oils, the clove bud and ylang ylang complete essential oils had the highest TEAC values, and the clove bud and jasmine absolute essential oils had the highest DFRS ability. At a concentration of 2.5 mg/mL, the clove bud and thyme borneol essential oils had RP and BCB activity levels of 94.56% ± 0.06% and 24.64% ± 0.03% and 94.58% ± 0.01% and 89.33% ± 0.09%, respectively. At a concentration of 1 mg/mL, the clove bud and thyme borneol essential oils showed TPC values of 220.00 ± 0.01 and 69.05 ± 0.01 mg/g relative to gallic acid equivalents, respectively, and the clove bud and ylang ylang complete essential oils had TEAC values of 809.00 ± 0.01 and 432.33 ± 0.01 μM, respectively. The clove bud and jasmine absolute essential oils showed DFRS abilities of 94.13% ± 0.01% and 78.62% ± 0.01%, respectively. Phenolic compounds of the clove bud, thyme borneol and jasmine absolute essential oils were eugenol (76.08%), thymol (14.36%) and carvacrol (12.33%), and eugenol (0.87%), respectively. The phenolic compounds in essential oils were positively correlated with the RP, BCB activity, TPC, TEAC, and DFRS ability. Copyright © 2017. Published by Elsevier B.V.

  12. Practical Stability Analysis and Synthesis of Linear Descriptor Systems with Disturbances

    Institute of Scientific and Technical Information of China (English)

    Chun-Yu Yang; Xin Jing; Qing-Ling Zhang; Lin-Na Zhou

    2008-01-01

    This paper considers the problems of practical stability analysis and synthesis of linear descriptor systems subject to time-varying and norm-bounded exogenous disturbances. A sufficient condition for the systems to be regular, impulsive-free and practically stable is derived. Then the synthesis problem is addressed and a state feedback controller is designed. To deal with the computational issue, the conditions of the main results are converted into linear matrix inequality (LMI) feasibility problems. Furthermore, two optimization algorithms are formulated to improve the system performances. Finally, numerical examples are given to illustrate the obtained results.

  13. Neurodynamics-Based Robust Pole Assignment for High-Order Descriptor Systems.

    Science.gov (United States)

    Le, Xinyi; Wang, Jun

    2015-11-01

    In this paper, a neurodynamic optimization approach is proposed for synthesizing high-order descriptor linear systems with state feedback control via robust pole assignment. With a new robustness measure serving as the objective function, the robust eigenstructure assignment problem is formulated as a pseudoconvex optimization problem. A neurodynamic optimization approach is applied and shown to be capable of maximizing the robust stability margin for high-order singular systems with guaranteed optimality and exact pole assignment. Two numerical examples and vehicle vibration control application are discussed to substantiate the efficacy of the proposed approach.

  14. Descriptor Fingerprints and Their Application to Red Wine Clustering and Discrimination

    Science.gov (United States)

    Bangov, I. P.; Moskovkina, M.; Stojanov, B. P.

    2017-03-01

    The investigation was performed to test the potentials of the fingerprint clustering algorithm for a set of 1599 red wines in relation to some wine properties, comprised in the notion "wine quality". We have obtained a distribution of the wines into different clusters as a result. Each cluster was composed of wine-objects with similar values of laboratory parameters and with a wine quality certificate. A correlation between the. quality of wines (a sensory taste factor) and the phisicochemical descriptors (laboratory analytical test results data) was observed and analyzed.

  15. Observer-based passive control for descriptor systems with time-delay

    Institute of Scientific and Technical Information of China (English)

    Li Qin; Zhang Qingling; Zhang Yanjuan; An Yichun

    2009-01-01

    This article is concerned with the problem of observer-based passive control for descriptor systems with time delay. Sufficient conditions are first presented for the closed loop systems to be admissible and passive with dissipation ηin the case of that the time delay is known, and two kinds of methods are given to design the expected observer. Then, the case of that the time delay is unknown or uncertain is discussed. The observer-based control gains could be obtained from the solutions of linear matrix inequalities (LMIs). Simulation examples are given to show the effectiveness of the designed methods.

  16. Non-fragile observer-based passive control for descriptor systems with time-delay

    Institute of Scientific and Technical Information of China (English)

    QinLI; Qingling ZHANG; Jichun WANG

    2009-01-01

    This paper investigates the problem of non-fragile observer-based passive control for descriptor systems with time-delay.The perturbations in both the control gain and observer gain of the observer-based controller are considered.For the cases of the additive perturbations and multiplicative perturbations,sufficient conditions are given such that the closed-loop systems are admissible and passive with dissipation 77.The observer-based controller gains could be obtained from the solutions of linear matrix inequalities (LMIs).Moreover,the maximum dissipation of the system is provided.Simulation examples are given to show the effectiveness of the deign methods.

  17. Calculation of Quantitative Structure-Activity Relationship Descriptors of Artemisinin Derivatives

    Directory of Open Access Journals (Sweden)

    Jambalsuren Bayarmaa

    2008-06-01

    Full Text Available Quantitative structure-activity relationships are based on the construction of predictive models using a set of known molecules and associated activity value. This accurate methodology, developed with adequate mathematical and computational tools, leads to a faster, cheaper and more comprehensive design of new products, reducing the experimental synthesis and testing on animals. Preparation of the QSAR models of artemisinin derivatives was carried out by the genetic function algorithm (GFA method for 91 molecules. The results show some relationships to the observed antimalarial activities of the artemisinin derivatives. The most statistically signi fi cant regression equation obtained from the fi nal GFA relates to two molecular descriptors.

  18. New descriptors of T-wave morphology are independent of heart rate

    DEFF Research Database (Denmark)

    Andersen, Mads Peter; Xue, Joel Q; Graff, Claus;

    2008-01-01

    by means of analysis of covariance. The results showed clear heart rate dependence for the QT interval (R(2) = 0.53-0.57) and a moderate degree of heart rate dependence for the basic morphology parameters (amplitude, area, and others) (R(2) = 0.17-0.42). Both the advanced T-wave descriptors (asymmetry......, flatness, and others), ToTe intervals and TpTe intervals, were practically independent of heart rate (R(2) = 0-0.08), making heart rate correction unnecessary for these parameters....

  19. Harmonization of sound insulation descriptors and classification schemes in Europe: COST Action TU0901

    DEFF Research Database (Denmark)

    Rasmussen, Birgit

    of the inhabitants and the society. References [1] "Sound insulation between dwellings – Descriptors in building regulations in Europe" by Birgit Rasmussen & Jens Holger Rindel. Applied Acoustics, 2010, 71(3), 171-180. http://dx.doi.org/10.1016/j.apacoust.2009.05.002 [2] "Sound insulation between dwellings...... – Requirements in building regulations in Europe" by Birgit Rasmussen. Applied Acoustics, 2010, 71(4), 373-385. http://dx.doi.org/10.1016/j.apacoust.2009.08.011 [3] "Sound insulation of residential housing – building codes and classification schemes in Europe" by Birgit Rasmussen. In: Crocker Malcolm J, Editor...

  20. A new positive real characterization and robust positive real control of descriptor systems

    Institute of Scientific and Technical Information of China (English)

    Hanyong SHAO; Chunbo FENG

    2005-01-01

    This paper investigates the positive real control problem for uncertain descriptor systems.The parametric uncertainty is assumed to be norm bounded.Firstly,for the nominal system,a new positive real characterization is given,which is expressed by a strict linear matrix inequality(LMI) without equality constraints.Secondly,for the uncertain system,necessary and sufficient conditions for the solvability of the positive real control problem are derived.Based on these conditioos a state feedback law is obtained,which renders the resultant closed-loop system robustly positive real.

  1. Discrimination Power of Polynomial-Based Descriptors for Graphs by Using Functional Matrices

    Science.gov (United States)

    Dehmer, Matthias; Emmert-Streib, Frank; Shi, Yongtang; Stefu, Monica; Tripathi, Shailesh

    2015-01-01

    In this paper, we study the discrimination power of graph measures that are based on graph-theoretical matrices. The paper generalizes the work of [M. Dehmer, M. Moosbrugger. Y. Shi, Encoding structural information uniquely with polynomial-based descriptors by employing the Randić matrix, Applied Mathematics and Computation, 268(2015), 164–168]. We demonstrate that by using the new functional matrix approach, exhaustively generated graphs can be discriminated more uniquely than shown in the mentioned previous work. PMID:26479495

  2. A QSPR STUDY OF NORMAL BOILING POINT OF ORGANIC COMPOUNDS (ALIPHATIC ALKANES USING MOLECULAR DESCRIPTORS

    Directory of Open Access Journals (Sweden)

    B. Souyei

    2013-12-01

    Full Text Available A quantitative structure–property relationship (QSPR study is carried out to develop correlations that relate the molecular structures of organic compounds (Aliphatic Alkanes to their normal boiling point (NBP and two correlations were proposed for constitutionals and connectivity indices Models. The correlations are simple in application with good accuracy, which provide an easy, direct and relatively accurate way to calculate NBP. Such calculation gives us a model that gives results in remarkable correlations with the descriptors of blokes constitutionals (CON, and connectivity indices (CI (R2 = 0.950, δ = 0.766 (R2 = 0.969, δ = 0.782 respectively.

  3. Predicting optimal finite field strengths for calculating the first and second hyperpolarizabilities using simple molecular descriptors

    Science.gov (United States)

    Mohammed, Ahmed A. K.; Limacher, Peter A.; Ayers, Paul W.

    2017-08-01

    The finite field method was used to calculate the static first and second hyperpolarizabilities (β and γ) for organic molecules. The dependence of β and γ on the applied electric field strength was investigated and used to determine the optimal field strength for each individual molecule. For γ, we designed a protocol that uses the maximum atomic distance within the molecule along the direction of the applied field to estimate optimal field strengths. However, β is nearly independent of the descriptors we considered, and largely depends on the composition (e.g., the presence of certain functional groups) of the molecule.

  4. Global Descriptor Attributes Based Content Based Image Retrieval of Query Images

    Directory of Open Access Journals (Sweden)

    Jaykrishna Joshi

    2015-02-01

    Full Text Available The need for efficient content-based image retrieval system has increased hugely. Efficient and effective retrieval techniques of images are desired because of the explosive growth of digital images. Content based image retrieval (CBIR is a promising approach because of its automatic indexing retrieval based on their semantic features and visual appearance. In this proposed system we investigate method for describing the contents of images which characterizes images by global descriptor attributes, where global features are extracted to make system more efficient by using color features which are color expectancy, color variance, skewness and texture feature correlation.

  5. Imaging descriptors improve the predictive power of survival models for glioblastoma patients.

    Science.gov (United States)

    Mazurowski, Maciej Andrzej; Desjardins, Annick; Malof, Jordan Milton

    2013-10-01

    Because effective prediction of survival time can be highly beneficial for the treatment of glioblastoma patients, the relationship between survival time and multiple patient characteristics has been investigated. In this paper, we investigate whether the predictive power of a survival model based on clinical patient features improves when MRI features are also included in the model. The subjects in this study were 82 glioblastoma patients for whom clinical features as well as MR imaging exams were made available by The Cancer Genome Atlas (TCGA) and The Cancer Imaging Archive (TCIA). Twenty-six imaging features in the available MR scans were assessed by radiologists from the TCGA Glioma Phenotype Research Group. We used multivariate Cox proportional hazards regression to construct 2 survival models: one that used 3 clinical features (age, gender, and KPS) as the covariates and 1 that used both the imaging features and the clinical features as the covariates. Then, we used 2 measures to compare the predictive performance of these 2 models: area under the receiver operating characteristic curve for the 1-year survival threshold and overall concordance index. To eliminate any positive performance estimation bias, we used leave-one-out cross-validation. The performance of the model based on both clinical and imaging features was higher than the performance of the model based on only the clinical features, in terms of both area under the receiver operating characteristic curve (P < .01) and the overall concordance index (P < .01). Imaging features assessed using a controlled lexicon have additional predictive value compared with clinical features when predicting survival time in glioblastoma patients.

  6. MultiDK: A Multiple Descriptor Multiple Kernel Approach for Molecular Discovery and Its Application to The Discovery of Organic Flow Battery Electrolytes

    CERN Document Server

    Kim, Sung-Jin; Aspuru-Guzik, Alán

    2016-01-01

    We propose a multiple descriptor multiple kernel (MultiDK) method for efficient molecular discovery using machine learning. We show that the MultiDK method improves both the speed and the accuracy of molecular property prediction. We apply the method to the discovery of electrolyte molecules for aqueous redox flow batteries. Using \\emph{multiple-type - as opposed to single-type - descriptors}, more relevant features for machine learning can be obtained. Following the principle of the 'wisdom of the crowds', the combination of multiple-type descriptors significantly boosts prediction performance. Moreover, MultiDK can exploit irregularities between molecular structure and property relations better than the linear regression method by employing multiple kernels - more than one kernel functions for a set of the input descriptors. The multiple kernels consist of the Tanimoto similarity function and a linear kernel for a set of binary descriptors and a set of non-binary descriptors, respectively. Using MultiDK, we...

  7. Allegheny County Land Cover Areas

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Land Cover dataset demarcates 14 land cover types by area; such as Residential, Commercial, Industrial, Forest, Agriculture, etc. If viewing this description on...

  8. Allegheny County Land Cover Areas

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Land Cover dataset demarcates 14 land cover types by area; such as Residential, Commercial, Industrial, Forest, Agriculture, etc. If viewing this description...

  9. Allegheny County Land Cover Areas

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Land Cover dataset demarcates 14 land cover types by area; such as Residential, Commercial, Industrial, Forest, Agriculture, etc. If viewing this description on...

  10. Space Constrained Dynamic Covering

    CERN Document Server

    Antonellis, Ioannis; Dughmi, Shaddin

    2009-01-01

    In this paper, we identify a fundamental algorithmic problem that we term space-constrained dynamic covering (SCDC), arising in many modern-day web applications, including ad-serving and online recommendation systems in eBay and Netflix. Roughly speaking, SCDC applies two restrictions to the well-studied Max-Coverage problem: Given an integer k, X={1,2,...,n} and I={S_1, ..., S_m}, S_i a subset of X, find a subset J of I, such that |J| <= k and the union of S in J is as large as possible. The two restrictions applied by SCDC are: (1) Dynamic: At query-time, we are given a query Q, a subset of X, and our goal is to find J such that the intersection of Q with the union of S in J is as large as possible; (2) Space-constrained: We don't have enough space to store (and process) the entire input; specifically, we have o(mn), sometimes even as little as O((m+n)polylog(mn)) space. The goal of SCDC is to maintain a small data structure so as to answer most dynamic queries with high accuracy. We present algorithms a...

  11. Descriptors of natural thermal regimes in streams and their responsiveness to change in the Pacific Northwest of North America

    Science.gov (United States)

    Arismendi, Ivan; Johnson, Sherri L.; Dunham, Jason B.; Haggerty, Roy

    2013-01-01

    1. Temperature is a major driver of ecological processes in stream ecosystems, yet the dynamics of thermal regimes remain poorly described. Most work has focused on relatively simple descriptors that fail to capture the full range of conditions that characterise thermal regimes of streams across seasons or throughout the year. 2. To more completely describe thermal regimes, we developed several descriptors of magnitude, variability, frequency, duration and timing of thermal events throughout a year. We evaluated how these descriptors change over time using long-term (1979–2009), continuous temperature data from five relatively undisturbed cold-water streams in western Oregon, U.S.A. In addition to trends for each descriptor, we evaluated similarities among them, as well as patterns of spatial coherence, and temporal synchrony. 3. Using different groups of descriptors, we were able to more fully capture distinct aspects of the full range of variability in thermal regimes across space and time. A subset of descriptors showed both higher coherence and synchrony and, thus, an appropriate level of responsiveness to examine evidence of regional climatic influences on thermal regimes. Most notably, daily minimum values during winter–spring were the most responsive descriptors to potential climatic influences. 4. Overall, thermal regimes in streams we studied showed high frequency and low variability of cold temperatures during the cold-water period in winter and spring, and high frequency and high variability of warm temperatures during the warm-water period in summer and autumn. The cold and warm periods differed in the distribution of events with a higher frequency and longer duration of warm events in summer than cold events in winter. The cold period exhibited lower variability in the duration of events, but showed more variability in timing. 5. In conclusion, our results highlight the importance of a year-round perspective in identifying the most responsive

  12. UNA PROPUESTA FUNCIONAL Y TIPOLÓGICA DE DESCRIPTORES SINTÁCTICOS PARA EL MAPUDUNGUN A functional and typological proposal of syntactic descriptors for mapuche language

    Directory of Open Access Journals (Sweden)

    Rodrigo Becerra Parra

    2011-07-01

    Full Text Available En este artículo se analiza la pertinencia de los descriptores sintácticos en uso en la lengua mapuche con el fin de enfrentar teóricamente la postura que espera reflejar su organización particular, con aquella otra que valora situarla en el concierto mundial de las lenguas. En el marco de la “Gramática Funcional Tipológica” de Talmy Givón (1983-1995-2001, este trabajo reconoce la importancia de las propiedades formales y pragmáticas y de su interrelación para el estudio de la sintaxis. Así, junto con discutir la denominación “persona focal”, este estudio presenta un análisis formal e informativo de la lengua mapuche. Como parte del primero, se analizan las propiedades de la “persona focal”, en tanto que el segundo considera el estudio de un corpus de siete cuentos mapuches. Ambos muestran que la “persona focal o axial” cumple de forma sistemática con las propiedades de la categoría “sujeto”.In this article, the adequacy of syntactic descriptors used in mapuche language I discuss, in order to confront theoretically those who want to reflectits particular syntactic organization, and those who prefer to put it into universal parameters. Sustained in the “Functional Typological Grammar” of Talmy Givón (1983-1995-2001, this paper recognize the importance of formal and pragmatic properties --as well as their connection-- for the study of syntax. In this basis, in addition to the discussion about the concepts in use, an analysis of mapuche grammatical categories is presented. So, the formal and pragmatic properties of “focal person” in mapuche are analized, and a corpus based study realized over seven mapuche tales is presented. Both parts of the study show that mapuche “focal person” is completely congruent with the formal and pragmatic properties of “subject”.

  13. Specific D-Admissibility and Design Issues for Uncertain Descriptor Systems with Parametric Uncertainty in the Derivative Matrix

    Directory of Open Access Journals (Sweden)

    Chih-Peng Huang

    2016-01-01

    Full Text Available Stability analysis issues and controller synthesis for descriptor systems with parametric uncertainty in the derivative matrix are discussed in this paper. The proposed descriptor system can extend the system’s modeling extent of physical and engineering systems from the traditional state-space model. First, based on the extended D-stability definitions for the descriptor model, necessary and sufficient admissibility and D-admissibility conditions for the unforced nominal descriptor system are derived and formulated by compact forms with strict linear matrix inequality (LMI manner. In contrast, existing results need to involve nonstrict LMIs, which cannot be evaluated by current LMI solvers and need some extra treatments. Deducing from the obtained distinct results, the roust admissibility and D-admissibility of the descriptor system with uncertainties in both the derivative matrix and the system’s matrices thus can be coped. Furthermore, by involving a proportional and derivative state feedback (PDSF control law, we further address the controller design for the resulting closed-loop systems. Since all the proposed criteria are explicitly expressed in terms of the strict LMIs, we can use applicable LMI solvers for evaluating the feasible solutions. Finally, the efficiency and practicability of the proposed approach are demonstrated by two illustrative examples.

  14. Role of descriptors in predicting the dissolution energy of embedded oxides and the bulk modulus of oxide-embedded iron

    Science.gov (United States)

    Takahashi, Keisuke; Tanaka, Yuzuru

    2017-01-01

    Oxide-embedded bulk iron is investigated in terms of first principles calculations and data mining. Twenty-nine oxides are embedded into a vacancy site of iron where first principles calculations are performed and the resulting calculations are stored as a data set. A prediction of the dissolution energy of oxides within iron and the bulk modulus of oxide-embedded iron is performed using machine learning. In particular, support vector machine (SVM) and linear regression (LR) are implemented where descriptors for determining the dissolution energy and bulk modulus are revealed. With trained SVM and LR, the prediction of the dissolution energy for different oxides in iron and the inverse problem—deriving the corresponding descriptor variables from a desired bulk modulus—are achieved. The physical origin behind the chosen descriptors is also revealed where manipulating each individual descriptor within a multidimensional space allows for the prediction of the dissolution energy and bulk modulus. Thus, predictions of physical phenomena are, in principle, achievable if the appropriate descriptors are determined.

  15. Similarity boosted quantitative structure-activity relationship--a systematic study of enhancing structural descriptors by molecular similarity.

    Science.gov (United States)

    Girschick, Tobias; Almeida, Pedro R; Kramer, Stefan; Stålring, Jonna

    2013-05-24

    The concept of molecular similarity is one of the most central in the fields of predictive toxicology and quantitative structure-activity relationship (QSAR) research. Many toxicological responses result from a multimechanistic process and, consequently, structural diversity among the active compounds is likely. Combining this knowledge, we introduce similarity boosted QSAR modeling, where we calculate molecular descriptors using similarities with respect to representative reference compounds to aid a statistical learning algorithm in distinguishing between different structural classes. We present three approaches for the selection of reference compounds, one by literature search and two by clustering. Our experimental evaluation on seven publicly available data sets shows that the similarity descriptors used on their own perform quite well compared to structural descriptors. We show that the combination of similarity and structural descriptors enhances the performance and that a simple stacking approach is able to use the complementary information encoded by the different descriptor sets to further improve predictive results. All software necessary for our experiments is available within the cheminformatics software framework AZOrange.

  16. QSPR models based on molecular mechanics and quantum chemical calculations. 1. Construction of Boltzmann averaged descriptors for alkanes, alcohols, diols, ethers and cyclic compounds

    DEFF Research Database (Denmark)

    Dyekjær, Jane Dannow; Rasmussen, Kjeld; Jonsdottir, Svava Osk

    2002-01-01

    Values for nine descriptors for QSPR (quantitative structure-property relationships) modeling of physical properties of 96 alkanes, alcohols, ethers, diols, triols and cyclic alkanes and alcohols in conjunction with the program Codessa are presented. The descriptors are Boltzmann-averaged by sele...... der Waals energies and the molecular polarizabilities, which correlate very well with boiling points. Five more simple descriptors that only depend on the molecular constitutional formula are also discussed briefly....

  17. Cover crops and N credits

    Science.gov (United States)

    Cover crops often provide many short- and long-term benefits to cropping systems. Legume cover crops can significantly reduce the N fertilizer requirement of non-legume cash crops that follow. The objectives of this presentation were to: I) educate stakeholders about the potential benefits of cover ...

  18. Is conformation a fundamental descriptor in QSAR? A case for halogenated anesthetics

    Science.gov (United States)

    Guimarães, Maria C; Duarte, Mariene H; Silla, Josué M

    2016-01-01

    Summary An intriguing question in 3D-QSAR lies on which conformation(s) to use when generating molecular descriptors (MD) for correlation with bioactivity values. This is not a simple task because the bioactive conformation in molecule data sets is usually unknown and, therefore, optimized structures in a receptor-free environment are often used to generate the MD´s. In this case, a wrong conformational choice can cause misinterpretation of the QSAR model. The present computational work reports the conformational analysis of the volatile anesthetic isoflurane (2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane) in the gas phase and also in polar and nonpolar implicit and explicit solvents to show that stable minima (ruled by intramolecular interactions) do not necessarily coincide with the bioconformation (ruled by enzyme induced fit). Consequently, a QSAR model based on two-dimensional chemical structures was built and exhibited satisfactory modeling/prediction capability and interpretability, then suggesting that these 2D MD´s can be advantageous over some three-dimensional descriptors. PMID:27340468

  19. Discriminative boosted forest with convolutional neural network-based patch descriptor for object detection

    Science.gov (United States)

    Xiang, Tao; Li, Tao; Ye, Mao; Li, Xudong

    2016-01-01

    Object detection with intraclass variations is challenging. The existing methods have not achieved the optimal combinations of classifiers and features, especially features learned by convolutional neural networks (CNNs). To solve this problem, we propose an object-detection method based on improved random forest and local image patches represented by CNN features. First, we compute CNN-based patch descriptors for each sample by modified CNNs. Then, the random forest is built whose split functions are defined by patch selector and linear projection learned by linear support vector machine. To improve the classification accuracy, the split functions in each depth of the forest make up a local classifier, and all local classifiers are assembled in a layer-wise manner by a boosting algorithm. The main contributions of our approach are summarized as follows: (1) We propose a new local patch descriptor based on CNN features. (2) We define a patch-based split function which is optimized with maximum class-label purity and minimum classification error over the samples of the node. (3) Each local classifier is assembled by minimizing the global classification error. We evaluate the method on three well-known challenging datasets: TUD pedestrians, INRIA pedestrians, and UIUC cars. The experiments demonstrate that our method achieves state-of-the-art or competitive performance.

  20. BioGPS descriptors for rational engineering of enzyme promiscuity and structure based bioinformatic analysis.

    Directory of Open Access Journals (Sweden)

    Valerio Ferrario

    Full Text Available A new bioinformatic methodology was developed founded on the Unsupervised Pattern Cognition Analysis of GRID-based BioGPS descriptors (Global Positioning System in Biological Space. The procedure relies entirely on three-dimensional structure analysis of enzymes and does not stem from sequence or structure alignment. The BioGPS descriptors account for chemical, geometrical and physical-chemical features of enzymes and are able to describe comprehensively the active site of enzymes in terms of "pre-organized environment" able to stabilize the transition state of a given reaction. The efficiency of this new bioinformatic strategy was demonstrated by the consistent clustering of four different Ser hydrolases classes, which are characterized by the same active site organization but able to catalyze different reactions. The method was validated by considering, as a case study, the engineering of amidase activity into the scaffold of a lipase. The BioGPS tool predicted correctly the properties of lipase variants, as demonstrated by the projection of mutants inside the BioGPS "roadmap".

  1. Chemical and Molecular Descriptors for the Reactivity of Amines with CO{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Anita S.; Kitchin, John R.

    2012-10-24

    Amine-based solvents are likely to play an important role in CO{sub 2} capture applications in the future, and the identification of amines with superior performance will facilitate their use in CO{sub 2} capture. While some improvements in performance will be achieved through process modifications, modifying the CO{sub 2} capture performance of an amine also implies in part an ability to modify the reactions between the amine and CO{sub 2} through development of new functionalized amines. We present a computational study of trends in the reactions between CO{sub 2} and functionalized amines with a focus on identifying molecular descriptors that determine trends in reactivity. We examine the formation of bicarbonate and carbamate species on three classes of functionalized amines: alkylamines, alkanolamines, and fluorinated alkylamines including primary, secondary and tertiary amines in each class. These functional groups span electron-withdrawing to donating behavior, hydrogen-bonding, extent of functionalization, and proximity effects of the functional groups. Electron withdrawing groups tend to destabilize CO{sub 2} reaction products, whereas electron-donating groups tend to stabilize CO{sub 2} reaction products. Hydrogen bonding stabilizes CO{sub 2} reaction products. Electronic structure descriptors based on electronegativity were found to describe trends in the bicarbonate formation energy. A chemical correlation was observed between the carbamate formation energy and the carbamic acid formation energy. The local softness on the reacting N in the amine was found to partially explain trends carbamic acid formation energy.

  2. Efficient descriptor of histogram of salient edge orientation map for finger vein recognition.

    Science.gov (United States)

    Lu, Yu; Yoon, Sook; Xie, Shan Juan; Yang, Jucheng; Wang, Zhihui; Park, Dong Sun

    2014-07-10

    Finger vein images are rich in orientation and edge features. Inspired by the edge histogram descriptor proposed in MPEG-7, this paper presents an efficient orientation-based local descriptor, named histogram of salient edge orientation map (HSEOM). HSEOM is based on the fact that human vision is sensitive to edge features for image perception. For a given image, HSEOM first finds oriented edge maps according to predefined orientations using a well-known edge operator and obtains a salient edge orientation map by choosing an orientation with the maximum edge magnitude for each pixel. Then, subhistograms of the salient edge orientation map are generated from the nonoverlapping submaps and concatenated to build the final HSEOM. In the experiment of this paper, eight oriented edge maps were used to generate a salient edge orientation map for HSEOM construction. Experimental results on our available finger vein image database, MMCBNU_6000, show that the performance of HSEOM outperforms that of state-of-the-art orientation-based methods (e.g., Gabor filter, histogram of oriented gradients, and local directional code). Furthermore, the proposed HSEOM has advantages of low feature dimensionality and fast implementation for a real-time finger vein recognition system.

  3. Automatic Descriptor-Based Co-Registration of Frame Hyperspectral Data

    Directory of Open Access Journals (Sweden)

    Maria Vakalopoulou

    2014-04-01

    Full Text Available Frame hyperspectral sensors, in contrast to push-broom or line-scanning ones, produce hyperspectral datasets with, in general, better geometry but with unregistered spectral bands. Being acquired at different instances and due to platform motion and movements (UAVs, aircrafts, etc., every spectral band is displaced and acquired with a different geometry. The automatic and accurate registration of hyperspectral datasets from frame sensors remains a challenge. Powerful local feature descriptors when computed over the spectrum fail to extract enough correspondences and successfully complete the registration procedure. To this end, we propose a generic and automated framework which decomposes the problem and enables the efficient computation of a sufficient amount of accurate correspondences over the given spectrum, without using any ancillary data (e.g., from GPS/IMU. First, the spectral bands are divided in spectral groups according to their wavelength. The spectral borders of each group are not strict and their formulation allows certain overlaps. The spectral variance and proximity determine the applicability of every spectral band to act as a reference during the registration procedure. The proposed decomposition allows the descriptor and the robust estimation process to deliver numerous inliers. The search space of possible solutions has been effectively narrowed by sorting and selecting the optimal spectral bands which under an unsupervised manner can quickly recover hypercube’s geometry. The developed approach has been qualitatively and quantitatively evaluated with six different datasets obtained by frame sensors onboard aerial platforms and UAVs. Experimental results appear promising.

  4. Probing intramolecular interactions in arylselenides using a property descriptor based approach.

    Science.gov (United States)

    Roy, Dipankar; Patel, Chandan; Liebman, Joel F; Sunoj, Raghavan B

    2008-09-18

    Although a large volume of experimental evidence is available on the existence of intramolecular nonbonding interactions between chalcogen atoms in main group organometallic compounds, the primary focus has been on the contact distances involving the chalcogen atoms. The important class of intramolecular Se...X (where X is O, S, N) nonbonding interaction in a series of organoselenium compounds is quantified using a new scheme based on a molecular property descriptor. In the present study, we have employed the nucleus-independent chemical shift [NICS(0)] values, as a property descriptor to evaluate the strength of exocyclic nonbonding interactions in a series of aryl selenides. The ab initio MP2 as well as density functional theory methods have been used in conjunction with Dunning's cc-pVDZ basis set. The quantified values of Se...X nonbonding interactions are compared with other schemes based on thermochemical equations such as homodesmic and ortho-para methods. The changes in NICS(0) values at the aryl ring center are found to be sensitive to the strength of exocyclic Se...X interaction.

  5. Time-frequency texture descriptors of EEG signals for efficient detection of epileptic seizure.

    Science.gov (United States)

    Şengür, Abdulkadir; Guo, Yanhui; Akbulut, Yaman

    2016-06-01

    Detection of epileptic seizure in electroencephalogram (EEG) signals is a challenging task and requires highly skilled neurophysiologists. Therefore, computer-aided detection helps neurophysiologist in interpreting the EEG. In this paper, texture representation of the time-frequency (t-f) image-based epileptic seizure detection is proposed. More specifically, we propose texture descriptor-based features to discriminate normal and epileptic seizure in t-f domain. To this end, three popular texture descriptors are employed, namely gray-level co-occurrence matrix (GLCM), texture feature coding method (TFCM), and local binary pattern (LBP). The features that are obtained on the GLCM are contrast, correlation, energy, and homogeneity. Moreover, in the TFCM method, several statistical features are calculated. In addition, for the LBP, the histogram is used as a feature. In the classification stage, a support vector machine classifier is employed. We evaluate our proposal with extensive experiments. According to the evaluated terms, our method produces successful results. 100 % accuracy is obtained with LIBLINEAR. We also compare our method with other published methods and the results show the superiority of our proposed method.

  6. Human Activity-Understanding: A Multilayer Approach Combining Body Movements and Contextual Descriptors Analysis

    Directory of Open Access Journals (Sweden)

    Consuelo Granata

    2015-07-01

    Full Text Available A deep understanding of human activity is key to successful human-robot interaction (HRI. The translation of sensed human behavioural signals/cues and context descriptors into an encoded human activity remains a challenge because of the complex nature of human actions. In this paper, we propose a multilayer framework for the understanding of human activity to be implemented in a mobile robot. It consists of a perception layer which exploits a D-RGB-based skeleton tracking output used to simulate a physical model of virtual human dynamics in order to compensate for the inaccuracy and inconsistency of the raw data. A multi-support vector machine (MSVM model trained with features describing the human motor coordination through temporal segments in combination with environment descriptors (object affordance is used to recognize each sub-activity (classification layer. The interpretation of sequences of classified elementary actions is based on discrete hidden Markov models (DHMMs (interpretation layer. The framework assessment was performed on the Cornell Activity Dataset (CAD-120 [1]. The performances of our method are comparable with those presented in [2] and clearly show the relevance of this model-based approach.

  7. Computational study of AuSin (n=1-9) nanoalloy clusters invoking DFT based descriptors

    Science.gov (United States)

    Ranjan, Prabhat; Kumar, Ajay; Chakraborty, Tanmoy

    2016-04-01

    Nanoalloy clusters formed between Au and Si are topics of great interest today from both scientific and technological point of view. Due to its remarkable catalytic, electronic, mechanical and magnetic properties Au-Si nanoalloy clusters have extensive applications in the field of microelectronics, catalysis, biomedicine, and jewelry industry. Density Functional Theory (DFT) is a new paradigm of quantum mechanics, which is very much popular to study the electronic properties of materials. Conceptual DFT based descriptors have been invoked to correlate the experimental properties of nanoalloy clusters. In this venture, we have systematically investigated AuSin (n=1-9) nanoalloy clusters in the theoretical frame of the B3LYP exchange correlation. The experimental properties of AuSin (n=1-9) nanoalloy clusters are correlated in terms of DFT based descriptors viz. HOMO-LUMO gap, Electronegativity (χ), Global Hardness (η), Global Softness (S) and Electrophilicity Index (ω). The calculated HOMO-LUMO gap exhibits interesting odd-even alteration behaviour, indicating that even numbered clusters possess higher stability as compare to their neighbour odd numbered clusters. This study also reflects a very well agreement between experimental bond length and computed data.

  8. Molecular Descriptors Family on Structure Activity Relationships 4. Molar Refraction of Cyclic Organophosphorus Compounds

    Directory of Open Access Journals (Sweden)

    Lorentz JÄNTSCHI

    2005-06-01

    Full Text Available The molecular descriptors family on structure activity relationships methodology was applied on ten cyclic organophosphorus compounds in order to predict theirs molar refraction. A number of 107692 significantly different MDF members enter into a multiple linear regression analysis. A pair of descriptors (lGDmSMt, lAmrfEt, which have the best performing ability in prediction of molar refraction of cyclic organophosphorus compounds, was found and a bi-varied MDF SAR model was built. After performing leave-one-out cross-validation, satisfactory result was obtained with cross-validation r2cv and r2 values of 0.9999 and 0.9999. The external validation of the bi-varied MDF SAR model and its ability in prediction of molar refraction of cyclic organophosphorus compounds is demonstrated by the results obtained in training vs. test experiment. The correlated correlation results proved us that the ability in prediction of molar refraction of cyclic organophosphorus compounds with bi-varied MDF SAR model is significantly better compared with the previous reported SAR (see pZ = 0.0 % from Steiger’s Z test. The results showed clearly that the molar refraction of cyclic organophosphorus compounds is almost of topological nature (99.99%, and is strongly dependent on atomic relative mass and atomic electronegativity.

  9. Reactivity Descriptors for the Activity of Molecular MN4 Catalysts for the Oxygen Reduction Reaction.

    Science.gov (United States)

    Zagal, José H; Koper, Marc T M

    2016-11-14

    Similarities are established between well-known reactivity descriptors of metal electrodes for their activity in the oxygen reduction reaction (ORR) and the reactivity of molecular catalysts, in particular macrocyclic MN4 metal complexes confined to electrode surfaces. We show that there is a correlation between the M(III) /M(II) redox potential of MN4 chelates and the M-O2 binding energies. Specifically, the binding energy of O2 (and other O species) follows the M(III) -OH/M(II) redox transition for MnN4 and FeN4 chelates. The ORR volcano plot for MN4 catalysts is similar to that for metal catalysts: catalysts on the weak binding side (mostly CoN4 chelates) yield mainly H2 O2 as the product, with an ORR onset potential independent of the pH value on the NHE scale (and therefore pH-dependent on the RHE scale); catalysts on the stronger binding side yield H2 O as the product with the expected pH-dependence on the NHE scale. The suggested descriptors also apply to heat-treated pyrolyzed MN4 catalysts. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. A Spherical Model Based Keypoint Descriptor and Matching Algorithm for Omnidirectional Images

    Directory of Open Access Journals (Sweden)

    Guofeng Tong

    2014-04-01

    Full Text Available Omnidirectional images generally have nonlinear distortion in radial direction. Unfortunately, traditional algorithms such as scale-invariant feature transform (SIFT and Descriptor-Nets (D-Nets do not work well in matching omnidirectional images just because they are incapable of dealing with the distortion. In order to solve this problem, a new voting algorithm is proposed based on the spherical model and the D-Nets algorithm. Because the spherical-based keypoint descriptor contains the distortion information of omnidirectional images, the proposed matching algorithm is invariant to distortion. Keypoint matching experiments are performed on three pairs of omnidirectional images, and comparison is made among the proposed algorithm, the SIFT and the D-Nets. The result shows that the proposed algorithm is more robust and more precise than the SIFT, and the D-Nets in matching omnidirectional images. Comparing with the SIFT and the D-Nets, the proposed algorithm has two main advantages: (a there are more real matching keypoints; (b the coverage range of the matching keypoints is wider, including the seriously distorted areas.

  11. Scene text recognition in mobile applications by character descriptor and structure configuration.

    Science.gov (United States)

    Yi, Chucai; Tian, Yingli

    2014-07-01

    Text characters and strings in natural scene can provide valuable information for many applications. Extracting text directly from natural scene images or videos is a challenging task because of diverse text patterns and variant background interferences. This paper proposes a method of scene text recognition from detected text regions. In text detection, our previously proposed algorithms are applied to obtain text regions from scene image. First, we design a discriminative character descriptor by combining several state-of-the-art feature detectors and descriptors. Second, we model character structure at each character class by designing stroke configuration maps. Our algorithm design is compatible with the application of scene text extraction in smart mobile devices. An Android-based demo system is developed to show the effectiveness of our proposed method on scene text information extraction from nearby objects. The demo system also provides us some insight into algorithm design and performance improvement of scene text extraction. The evaluation results on benchmark data sets demonstrate that our proposed scheme of text recognition is comparable with the best existing methods.

  12. Descriptors of Modular Formation of Accounting and Analytical Cluster in Innovation Development of Agricultural Holdings

    Directory of Open Access Journals (Sweden)

    Zhanna Degaltseva

    2015-11-01

    Full Text Available In the context of the division of accounting into financial accounting, taxation accounting, management accounting and statistical accounting a problem of improving their relationship arises. The accounting and analytical cluster plays the role of the correlating factor of the relationship between the subdivisions of the agricultural holding property. To improve its work a modular principle of its building based on information technology was introduced. Practical implementation of modular accounting and analytical cluster revealed its shortcomings. They were as follows: each type of account and each production unit used its own natural and cost parameters. The number and nature of these parameters were different. To eliminate the shortcomings in the information security of managers and specialists of the agricultural holding, we attempt to develop a methodology for establishing a rational number of descriptors (binding parameters for each module. The proposed descriptors are designed on the basis of validity of the methodological approach to their calculations and legal support. The proposed method allowed to limit the asymmetric information in all kinds of records, to improve its quality and to bring a synergistic effect from the scale and structure of the use of the agricultural holdings property complex.

  13. Dissecting molecular descriptors into atomic contributions in density functional reactivity theory.

    Science.gov (United States)

    Rong, Chunying; Lu, Tian; Liu, Shubin

    2014-01-14

    Density functional reactivity theory (DFRT) employs the electron density of a molecule and its related quantities such as gradient and Laplacian to describe its structure and reactivity properties. Proper descriptions at both molecular (global) and atomic (local) levels are equally important and illuminating. In this work, we make use of Bader's zero-flux partition scheme and consider atomic contributions for a few global reactivity descriptors in DFRT, including the density-based quantification of steric effect and related indices. Earlier, we proved that these quantities are intrinsically correlated for atomic and molecular systems [S. B. Liu, J. Chem. Phys. 126, 191107 (2007); ibid. 126, 244103 (2007)]. In this work, a new basin-based integration algorithm has been implemented, whose reliability and effectiveness have been extensively examined. We also investigated a list of simple hydrocarbon systems and different scenarios of bonding processes, including stretching, bending, and rotating. Interesting changing patterns for the atomic and molecular values of these quantities have been revealed for different systems. This work not only confirms the strong correlation between these global reactivity descriptors for molecular systems, as theoretically proven earlier by us, it also provides new and unexpected changing patterns for their atomic values, which can be employed to understand the origin and nature of chemical phenomena.

  14. Evaluation of MPEG-7-Based Audio Descriptors for Animal Voice Recognition over Wireless Acoustic Sensor Networks.

    Science.gov (United States)

    Luque, Joaquín; Larios, Diego F; Personal, Enrique; Barbancho, Julio; León, Carlos

    2016-05-18

    Environmental audio monitoring is a huge area of interest for biologists all over the world. This is why some audio monitoring system have been proposed in the literature, which can be classified into two different approaches: acquirement and compression of all audio patterns in order to send them as raw data to a main server; or specific recognition systems based on audio patterns. The first approach presents the drawback of a high amount of information to be stored in a main server. Moreover, this information requires a considerable amount of effort to be analyzed. The second approach has the drawback of its lack of scalability when new patterns need to be detected. To overcome these limitations, this paper proposes an environmental Wireless Acoustic Sensor Network architecture focused on use of generic descriptors based on an MPEG-7 standard. These descriptors demonstrate it to be suitable to be used in the recognition of different patterns, allowing a high scalability. The proposed parameters have been tested to recognize different behaviors of two anuran species that live in Spanish natural parks; the Epidalea calamita and the Alytes obstetricans toads, demonstrating to have a high classification performance.

  15. Multi-resolution cell orientation congruence descriptors for epithelium segmentation in endometrial histology images.

    Science.gov (United States)

    Li, Guannan; Raza, Shan E Ahmed; Rajpoot, Nasir M

    2017-04-01

    It has been recently shown that recurrent miscarriage can be caused by abnormally high ratio of number of uterine natural killer (UNK) cells to the number of stromal cells in human female uterus lining. Due to high workload, the counting of UNK and stromal cells needs to be automated using computer algorithms. However, stromal cells are very similar in appearance to epithelial cells which must be excluded in the counting process. To exclude the epithelial cells from the counting process it is necessary to identify epithelial regions. There are two types of epithelial layers that can be encountered in the endometrium: luminal epithelium and glandular epithelium. To the best of our knowledge, there is no existing method that addresses the segmentation of both types of epithelium simultaneously in endometrial histology images. In this paper, we propose a multi-resolution Cell Orientation Congruence (COCo) descriptor which exploits the fact that neighbouring epithelial cells exhibit similarity in terms of their orientations. Our experimental results show that the proposed descriptors yield accurate results in simultaneously segmenting both luminal and glandular epithelium.

  16. Cardiac Arrhythmias Classification Method Based on MUSIC, Morphological Descriptors, and Neural Network

    Directory of Open Access Journals (Sweden)

    2009-03-01

    Full Text Available An electrocardiogram (ECG beat classification scheme based on multiple signal classification (MUSIC algorithm, morphological descriptors, and neural networks is proposed for discriminating nine ECG beat types. These are normal, fusion of ventricular and normal, fusion of paced and normal, left bundle branch block, right bundle branch block, premature ventricular concentration, atrial premature contraction, paced beat, and ventricular flutter. ECG signal samples from MIT-BIH arrhythmia database are used to evaluate the scheme. MUSIC algorithm is used to calculate pseudospectrum of ECG signals. The low-frequency samples are picked to have the most valuable heartbeat information. These samples along with two morphological descriptors, which deliver the characteristics and features of all parts of the heart, form an input feature vector. This vector is used for the initial training of a classifier neural network. The neural network is designed to have nine sample outputs which constitute the nine beat types. Two neural network schemes, namely multilayered perceptron (MLP neural network and a probabilistic neural network (PNN, are employed. The experimental results achieved a promising accuracy of 99.03% for classifying the beat types using MLP neural network. In addition, our scheme recognizes NORMAL class with 100% accuracy and never misclassifies any other classes as NORMAL.

  17. Cardiac Arrhythmias Classification Method Based on MUSIC, Morphological Descriptors, and Neural Network

    Science.gov (United States)

    Naghsh-Nilchi, Ahmad R.; Kadkhodamohammadi, A. Rahim

    2009-12-01

    An electrocardiogram (ECG) beat classification scheme based on multiple signal classification (MUSIC) algorithm, morphological descriptors, and neural networks is proposed for discriminating nine ECG beat types. These are normal, fusion of ventricular and normal, fusion of paced and normal, left bundle branch block, right bundle branch block, premature ventricular concentration, atrial premature contraction, paced beat, and ventricular flutter. ECG signal samples from MIT-BIH arrhythmia database are used to evaluate the scheme. MUSIC algorithm is used to calculate pseudospectrum of ECG signals. The low-frequency samples are picked to have the most valuable heartbeat information. These samples along with two morphological descriptors, which deliver the characteristics and features of all parts of the heart, form an input feature vector. This vector is used for the initial training of a classifier neural network. The neural network is designed to have nine sample outputs which constitute the nine beat types. Two neural network schemes, namely multilayered perceptron (MLP) neural network and a probabilistic neural network (PNN), are employed. The experimental results achieved a promising accuracy of 99.03% for classifying the beat types using MLP neural network. In addition, our scheme recognizes NORMAL class with 100% accuracy and never misclassifies any other classes as NORMAL.

  18. Assessing diversity among traditional Greek and foreign eggplant cultivars using molecular markers and morphometrical descriptors

    Directory of Open Access Journals (Sweden)

    Antonios A. Augustinos

    2016-12-01

    Full Text Available Eggplant is a widely cultivated vegetable crop of great economic importance. Its long lasting history of domestication, selection and breeding has led to the development of numerous cultivars with variable traits. In the present study, we assessed the diversity levels within and among eleven Greek and foreign cultivars, using 22 morphological descriptors and two different classes of molecular markers (retrotransposon microsatellite amplified polymorphism-REMAP markers and nuclear microsatellites. Our results, in accordance with other studies in the field showed: a the limited levels of genetic polymorphism within the cultivars; b the high morphological and genetic divergence existing among them as indicated by the genetic distance values calculated, which could be attributed to selection, inbreeding and bottleneck effects; and c the lack of concordance among morphological descriptors and molecular markers. Despite these, our analysis showed that the utilization of combinations of markers is an effective method for the characterization of plant material providing also useful diagnostic tools for the identification and authentication of the selected Greek cultivars.

  19. A partial intensity invariant feature descriptor for multimodal retinal image registration.

    Science.gov (United States)

    Chen, Jian; Tian, Jie; Lee, Noah; Zheng, Jian; Smith, R Theodore; Laine, Andrew F

    2010-07-01

    Detection of vascular bifurcations is a challenging task in multimodal retinal image registration. Existing algorithms based on bifurcations usually fail in correctly aligning poor quality retinal image pairs. To solve this problem, we propose a novel highly distinctive local feature descriptor named partial intensity invariant feature descriptor (PIIFD) and describe a robust automatic retinal image registration framework named Harris-PIIFD. PIIFD is invariant to image rotation, partially invariant to image intensity, affine transformation, and viewpoint/perspective change. Our Harris-PIIFD framework consists of four steps. First, corner points are used as control point candidates instead of bifurcations since corner points are sufficient and uniformly distributed across the image domain. Second, PIIFDs are extracted for all corner points, and a bilateral matching technique is applied to identify corresponding PIIFDs matches between image pairs. Third, incorrect matches are removed and inaccurate matches are refined. Finally, an adaptive transformation is used to register the image pairs. PIIFD is so distinctive that it can be correctly identified even in nonvascular areas. When tested on 168 pairs of multimodal retinal images, the Harris-PIIFD far outperforms existing algorithms in terms of robustness, accuracy, and computational efficiency.

  20. SMILES-based optimal descriptors: QSAR modeling of carcinogenicity by balance of correlations with ideal slopes.

    Science.gov (United States)

    Toropov, A A; Toropova, A P; Benfenati, E

    2010-09-01

    Optimal descriptors which are calculated using the simplified molecular input line entry system (SMILES) were utilized to build quantitative structure-activity relationships (QSAR) of carcinogenicity (log TD50). Three schemes of the modeling have been examined: 1. The most traditional "classic" training-test system, i.e., models are built with training set and validated with external test set; 2. The correlation balance, i.e., models are built with preliminary estimation of the predictability of the model with the calibration set (this set plays a role of preliminary test set); and 3. The extended correlation balance that takes into account the slopes of regression lines in plots experimental versus predicted values of carcinogenicity (in ideal, these slopes should be similar). It has been shown that the extended correlation balance with the ideal slopes gives most robust prediction of carcinogenicity for external test set. These models have been built by Monte Carlo method for three splits into subtraining set, calibration set, and test set. The number of the N-nitroso groups (i.e., R1-N(R2)-N=O) in a molecular system has been examined as an additional descriptor. 2010 Elsevier Masson SAS. All rights reserved.

  1. Hybrid optimal descriptors as a tool to predict skin sensitization in accordance to OECD principles.

    Science.gov (United States)

    Toropova, Alla P; Toropov, Andrey A

    2017-06-05

    Skin sensitization (allergic contact dermatitis) is a widespread problem arising from the contact of chemicals with the skin. The detection of molecular features with undesired effect for skin is complex task owing to unclear biochemical mechanisms and unclearness of conditions of action of chemicals to skin. The development of computational methods for estimation of this endpoint in order to reduce animal testing is recommended (Cosmetics Directive EC regulation 1907/2006; EU Regulation, Regulation, 1223/2009). The CORAL software (http://www.insilico.eu/coral) gives good predictive models for the skin sensitization. Simplified molecular input-line entry system (SMILES) together with molecular graph are used to represent the molecular structure for these models. So-called hybrid optimal descriptors are used to establish quantitative structure-activity relationships (QSARs). The aim of this study is the estimation of the predictive potential of the hybrid descriptors. Three different distributions into the training (≈70%), calibration (≈15%), and validation (≈15%) sets are studied. QSAR for these three distributions are built up with using the Monte Carlo technique. The statistical characteristics of these models for external validation set are used as a measure of predictive potential of these models. The best model, according to the above criterion, is characterized by nvalidation=29, r(2)validation=0.8596, RMSEvalidation=0.489. Mechanistic interpretation and domain of applicability for these models are defined. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Advances in structural damage assessment using strain measurements and invariant shape descriptors

    Science.gov (United States)

    Patki, Amol Suhas

    to the area surrounding the damage, while damage in orthotropic materials tends to have more global repercussions. This calls for analysis of full-field strain distributions adding to the complexity of post-damage life estimation. This study explores shape descriptors used in the field of medical imagery, military targeting and biometric recognition for obtaining a qualitative and quantitative comparison between full-field strain data recorded from damaged composite panels using sophisticated experimental techniques. These descriptors are capable of decomposing images with 103 to 106 pixels into a feature vector with only a few hundred elements. This ability of shape descriptors to achieve enormous reduction in strain data, while providing unique representation, makes them a practical choice for the purpose of structural damage assessment. Consequently, it is relatively easy to statistically compare the shape descriptors of the full-field strain maps using similarity measures rather than the strain maps themselves. However, the wide range of geometric and design features in engineering components pose difficulties in the application of traditional shape description techniques. Thus a new shape descriptor is developed which is applicable to a wide range of specimen geometries. This work also illustrates how shape description techniques can be applied to full-field finite element model validations and updating.

  3. On L-injective Covers

    Institute of Scientific and Technical Information of China (English)

    周德旭

    2004-01-01

    We use the class of L-injective modules to define L-injective covers, and provide the characterizations of L-injective covers by the properties of kernels of homomorphisms. We prove that the right L-noetherian right L-hereditary ring is just such that every right R-module has an L-injective cover which is monic. We also use kernels of homomorphisms to investigate L-simple L-injective covers and give some constructions ofL-simple L-iniective covers.

  4. Identification of Electronic and Structural Descriptors of Adenosine Analogues Related to Inhibition of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase

    Directory of Open Access Journals (Sweden)

    Norka B. H. Lozano

    2013-04-01

    Full Text Available Quantitative structure–activity relationship (QSAR studies were performed in order to identify molecular features responsible for the antileishmanial activity of 61 adenosine analogues acting as inhibitors of the enzyme glyceraldehyde 3-phosphate dehydrogenase of Leishmania mexicana (LmGAPDH. Density functional theory (DFT was employed to calculate quantum-chemical descriptors, while several structural descriptors were generated with Dragon 5.4. Variable selection was undertaken with the ordered predictor selection (OPS algorithm, which provided a set with the most relevant descriptors to perform PLS, PCR and MLR regressions. Reliable and predictive models were obtained, as attested by their high correlation coefficients, as well as the agreement between predicted and experimental values for an external test set. Additional validation procedures were carried out, demonstrating that robust models were developed, providing helpful tools for the optimization of the antileishmanial activity of adenosine compounds.

  5. Using three-dimensional discrete spherical Fourier descriptors based on surface curvature voxels for pollen particle recognition

    Institute of Scientific and Technical Information of China (English)

    Xie Yong-Hua; Michael OhEigeartaigh

    2010-01-01

    This paper presents a new method for extract three-dimensional (3D) discrete spherical Fourier descriptors based on surface curvature voxeis for pollen particle recognition.In order to reduce the high amount of pollen information and noise disturbance,the geometric normalized curvature voxels with the principal curvedness are first extracted to represent the intrinsic pollen volumetric data.Then the curvature voxels are decomposed into radial and angular components with spherical harmonic transform in spherical coordinates.Finally the 3D discrete Fourier transform is applied to the decomposed curvature voxels to obtain the 3D spherical Fourier descriptors for pollen recognition.Experimental results show that the presented descriptors are invariant to different pollen particle geometric transformations,such as pose change and spatial rotation,and can obtain high recognition accuracy and speed simultaneously.

  6. Prediction of gas chromatographic retention times of polychlorinated biphenyls by mono-dimensional molecular descriptors and multivariate techniques

    Energy Technology Data Exchange (ETDEWEB)

    Mecozzi, M.; Amici, M. [Istituto Centrale per la Ricerca Scientifica e Technological Applicata al Mare, Rome (Italy); Acquistucci, R. [Istituto Nazionale per la Nutrizione e gli Alimenti, Rome (Italy)

    2003-07-01

    We report a procedure for describing the gas chromatographic retention time of polychlorinated biphenyls (PCBs) as a function of simple mono-dimensional molecular descriptors such as the number and position of chlorine atoms on the aromatic rings. The mathematical relationships between relative retention time (RRT) of all 209 possible congeners of PCBs and the mono-dimensional molecular descriptors (MDDs) were obtained by the multivariate techniques principal component regression (PCR) and partial least squares (PLS) used as modelling tools. The good agreement found between experimental and predicted retention times of PCBs shows that a well established mathematical model relating retention time to specific mono-dimensional molecular descriptors can be a useful tool to enhance identification of these pollutants in real samples. (orig.)

  7. Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(IV) complexes.

    Science.gov (United States)

    Ermondi, Giuseppe; Caron, Giulia; Ravera, Mauro; Gabano, Elisabetta; Bianco, Sabrina; Platts, James A; Osella, Domenico

    2013-03-14

    We report QSAR calculations using VolSurf descriptors to model the lipophilicity of 53 Pt(iv) complexes with a diverse range of axial and equatorial ligands. Lipophilicity is measured using an efficient HPLC method. Previous models based on a subset of these data are shown to be inadequate, due to incompatibility of whole molecule descriptors between carboxylato and hydroxido ligands. Instead, the interaction surfaces of complexes with various probes are used as independent descriptors. Partial least squares modelling using three latent variables results in an accurate (R(2) = 0.92) and robust model (Q(2) = 0.87) of lipophilicity, that moreover highlights the importance of size and hydrophobicity terms and the modest relevance of hydrogen bonding.

  8. Correlation between electronic parameters and corrosion inhibition of benzothiazole derivatives- NMR parameters as important and neglected descriptors

    Science.gov (United States)

    Behzadi, Hadi; Forghani, Ali

    2017-03-01

    The relation between electronic properties and corrosion inhibitive performance of three benzothiazole derivatives 1,3-benzothiazol-2-amine (BTA), 6-methyl-1,3-benzothiazol-2-amine (MBTA) and 2-amino-1,3-benzthiazole-6-thiol (TBTA) has been investigated by density functional theory. The electronic properties including EHOMO, ELUMO and related parameters were calculated at the B3LYP/6-311++G(d,p) level. The chemical shielding CS tensors were introduced as important and neglected descriptors to evaluate inhibitive efficiency of corrosion inhibitors. Nuclear independent chemical shift (NICS) components, as an aromaticity criterion, were also investigated as local descriptor. Polarizability and CS descriptors, as second rank tensors, show the best correlations with inhibition efficiencies of studied inhibitors.

  9. Conceptual DFT Descriptors of Amino Acids with Potential Corrosion Inhibition Properties Calculated with the Latest Minnesota Density Functionals

    Science.gov (United States)

    Frau, Juan; Glossman-Mitnik, Daniel

    2017-01-01

    Amino acids and peptides have the potential to perform as corrosion inhibitors. The chemical reactivity descriptors that arise from Conceptual DFT for the twenty natural amino acids have been calculated by using the latest Minnesota family of density functionals. In order to verify the validity of the calculation of the descriptors directly from the HOMO and LUMO, a comparison has been performed with those obtained through ΔSCF results. Moreover, the active sites for nucleophilic and electrophilic attacks have been identified through Fukui function indices, the dual descriptor Δf(r) and the electrophilic and nucleophilic Parr functions. The results could be of interest as a starting point for the study of large peptides where the calculation of the radical cation and anion of each system may be computationally harder and costly. PMID:28361050

  10. Prediction of infinite dilution activity coefficients of chlorinated organic compounds in aqueous solution from quantum-chemical descriptors.

    Science.gov (United States)

    Delgado, Eduardo J.; Alderete, Joel B.

    2001-11-30

    A quantitative structure-property relationship (QSPR) model is developed to correlate the natural logarithm of infinite dilution activity coefficients, ln (gamma(infinity)), of 45 chlorinated organic compounds in aqueous solution from quantum-chemical descriptors. The best correlation equation contains five theoretical molecular descriptors. All descriptors were obtained from the chemical structure of the compounds and have definite physical meaning corresponding to different intermolecular interactions. The model predicts ln (gamma(infinity)) with a correlation coefficients of 0.949 and a standard error of 0.442 ln units. The obtained QSPR equation may be applied to the prediction of gamma(infinity) of other chlorinated organic compounds not present in the data set used for the development of the present model. Copyright 2001 John Wiley & Sons, Inc. J Comput Chem 22: 1851-1856, 2001

  11. A novel approach for weed type classification based on shape descriptors and a fuzzy decision-making method.

    Science.gov (United States)

    Herrera, Pedro Javier; Dorado, José; Ribeiro, Ángela

    2014-08-19

    An important objective in weed management is the discrimination between grasses (monocots) and broad-leaved weeds (dicots), because these two weed groups can be appropriately controlled by specific herbicides. In fact, efficiency is higher if selective treatment is performed for each type of infestation instead of using a broadcast herbicide on the whole surface. This work proposes a strategy where weeds are characterised by a set of shape descriptors (the seven Hu moments and six geometric shape descriptors). Weeds appear in outdoor field images which display real situations obtained from a RGB camera. Thus, images present a mixture of both weed species under varying conditions of lighting. In the presented approach, four decision-making methods were adapted to use the best shape descriptors as attributes and a choice was taken. This proposal establishes a novel methodology with a high success rate in weed species discrimination.

  12. A Novel Approach for Weed Type Classification Based on Shape Descriptors and a Fuzzy Decision-Making Method

    Directory of Open Access Journals (Sweden)

    Pedro Javier Herrera

    2014-08-01

    Full Text Available An important objective in weed management is the discrimination between grasses (monocots and broad-leaved weeds (dicots, because these two weed groups can be appropriately controlled by specific herbicides. In fact, efficiency is higher if selective treatment is performed for each type of infestation instead of using a broadcast herbicide on the whole surface. This work proposes a strategy where weeds are characterised by a set of shape descriptors (the seven Hu moments and six geometric shape descriptors. Weeds appear in outdoor field images which display real situations obtained from a RGB camera. Thus, images present a mixture of both weed species under varying conditions of lighting. In the presented approach, four decision-making methods were adapted to use the best shape descriptors as attributes and a choice was taken. This proposal establishes a novel methodology with a high success rate in weed species discrimination.

  13. Conceptual DFT Descriptors of Amino Acids with Potential Corrosion Inhibition Properties Calculated with the Latest Minnesota Density Functionals.

    Science.gov (United States)

    Frau, Juan; Glossman-Mitnik, Daniel

    2017-01-01

    Amino acids and peptides have the potential to perform as corrosion inhibitors. The chemical reactivity descriptors that arise from Conceptual DFT for the twenty natural amino acids have been calculated by using the latest Minnesota family of density functionals. In order to verify the validity of the calculation of the descriptors directly from the HOMO and LUMO, a comparison has been performed with those obtained through ΔSCF results. Moreover, the active sites for nucleophilic and electrophilic attacks have been identified through Fukui function indices, the dual descriptor Δf(r) and the electrophilic and nucleophilic Parr functions. The results could be of interest as a starting point for the study of large peptides where the calculation of the radical cation and anion of each system may be computationally harder and costly.

  14. Effect of number of probes and their orientation on the calculation of several compressor face distortion descriptors

    Science.gov (United States)

    Stoll, F.; Tremback, J. W.; Arnaiz, H. H.

    1979-01-01

    A study was performed to determine the effects of the number and position of total pressure probes on the calculation of five compressor face distortion descriptors. This study used three sets of 320 steady state total pressure measurements that were obtained with a special rotating rake apparatus in wind tunnel tests of a mixed-compression inlet. The inlet was a one third scale model of the inlet on a YF-12 airplane, and it was tested in the wind tunnel at representative flight conditions at Mach numbers above 2.0. The study shows that large errors resulted in the calculation of the distortion descriptors even with a number of probes that were considered adequate in the past. There were errors as large as 30 and -50 percent in several distortion descriptors for a configuration consisting of eight rakes with five equal-area-weighted probes on each rake.

  15. Predicting allergic contact dermatitis: a hierarchical structure activity relationship (SAR) approach to chemical classification using topological and quantum chemical descriptors

    Science.gov (United States)

    Basak, Subhash C.; Mills, Denise; Hawkins, Douglas M.

    2008-06-01

    A hierarchical classification study was carried out based on a set of 70 chemicals—35 which produce allergic contact dermatitis (ACD) and 35 which do not. This approach was implemented using a regular ridge regression computer code, followed by conversion of regression output to binary data values. The hierarchical descriptor classes used in the modeling include topostructural (TS), topochemical (TC), and quantum chemical (QC), all of which are based solely on chemical structure. The concordance, sensitivity, and specificity are reported. The model based on the TC descriptors was found to be the best, while the TS model was extremely poor.

  16. Performance of Kier-Hall E-state Descriptors in Quantitative Structure Activity Relationship (QSAR Studies of Multifunctional Molecules

    Directory of Open Access Journals (Sweden)

    Darko Butina

    2004-12-01

    Full Text Available Performance of the E-state descriptors was tested against simple counts of the 35 atom types that the Kier-Hall E-states are based upon, by building PLS models for clogP, aqueous solubility, human intestinal absorption (HIA and blood brain barrier (BBB. The results indicate that the simple counts work at least as well as E-state descriptors in building models for solubility and BBB, while surprisingly, simple counts have outperformed E-states by 18% and 30%, respectively, when building the models for HIA and clogP.

  17. Cell nucleus architecture in health and medicine: geometrical descriptors and their use in grid based case studies.

    Science.gov (United States)

    Schmitt, Eberhard; Müller, Patrick; Stein, Stefan; Schwarz-Finsterle, Jutta; Hausmann, Michael

    2010-01-01

    Adopting the world wide accessible Grid computing power and data management structures enables usage of large image data bases for individual diagnosis and therapy decisions. Here, we define several descriptors of the genome architecture of cell nuclei which are the basis of a detailed analysis for conclusions on the health state of an individual patient. All these descriptors can be accessed by automatic inspection of microscopic images of fluorescently labelled nuclei, obtained from cells from tissue sections or blood and subjected to standard biochemical protocols. We demonstrate how the combinatorial, geometrical and statistical parameters may be used in diagnosis and therapy monitoring.

  18. Microstructural descriptors and cellular automata simulation of the effects of non-random nuclei location on recrystallization in two dimensions

    Directory of Open Access Journals (Sweden)

    Paulo Rangel Rios

    2006-06-01

    Full Text Available The effect of non-random nuclei location and the efficiency of microstructural descriptors in assessing such a situation are studied. Cellular automata simulation of recrystallization in two dimensions is carried out to simulate microstrutural evolution for nuclei distribution ranging from a periodic arrangement to clusters of nuclei. The simulation results are compared in detail with microstrutural descriptors normally used to follow transformation evolution. It is shown that the contiguity is particularly relevant to detect microstructural deviations from randomness. This work focuses on recrystallization but its results are applicable to any nucleation and growth transformation.

  19. Reactivity descriptors and electron density analysis for ligand chemistry: A case study of 2,2'-bipyridine and its analogues

    Indian Academy of Sciences (India)

    Bhakti S Kulkarni; Akhilesh Tanwar; Sourav Pal

    2007-09-01

    In this paper, we study the reactivity of diimines like 2,2'-bipyridine and its analogues using reactivity descriptors. We discuss evaluation of local descriptors using relaxed as well as frozen approximation and characterize the / acceptance/donor characteristics of the above ligands. The intermolecular reactivity sequence for the same systems is examined by the global and local philicity index. In addition, electron density analysis has been carried out to highlight the possible strengths of interaction of the bipyridine and its analogues with metal ions.

  20. Quantitative structure-activity relationship modeling of polycyclic aromatic hydrocarbon mutagenicity by classification methods based on holistic theoretical molecular descriptors.

    Science.gov (United States)

    Gramatica, Paola; Papa, Ester; Marrocchi, Assunta; Minuti, Lucio; Taticchi, Aldo

    2007-03-01

    Various polycyclic aromatic hydrocarbons (PAHs), ubiquitous environmental pollutants, are recognized mutagens and carcinogens. A homogeneous set of mutagenicity data (TA98 and TA100,+S9) for 32 benzocyclopentaphenanthrenes/chrysenes was modeled by the quantitative structure-activity relationship classification methods k-nearest neighbor and classification and regression tree, using theoretical holistic molecular descriptors. Genetic algorithm provided the selection of the best subset of variables for modeling mutagenicity. The models were validated by leave-one-out and leave-50%-out approaches and have good performance, with sensitivity and specificity ranges of 90-100%. Mutagenicity assessment for these PAHs requires only a few theoretical descriptors of their molecular structure.

  1. Protein-protein docking using region-based 3D Zernike descriptors

    Directory of Open Access Journals (Sweden)

    Sael Lee

    2009-12-01

    Full Text Available Abstract Background Protein-protein interactions are a pivotal component of many biological processes and mediate a variety of functions. Knowing the tertiary structure of a protein complex is therefore essential for understanding the interaction mechanism. However, experimental techniques to solve the structure of the complex are often found to be difficult. To this end, computational protein-protein docking approaches can provide a useful alternative to address this issue. Prediction of docking conformations relies on methods that effectively capture shape features of the participating proteins while giving due consideration to conformational changes that may occur. Results We present a novel protein docking algorithm based on the use of 3D Zernike descriptors as regional features of molecular shape. The key motivation of using these descriptors is their invariance to transformation, in addition to a compact representation of local surface shape characteristics. Docking decoys are generated using geometric hashing, which are then ranked by a scoring function that incorporates a buried surface area and a novel geometric complementarity term based on normals associated with the 3D Zernike shape description. Our docking algorithm was tested on both bound and unbound cases in the ZDOCK benchmark 2.0 dataset. In 74% of the bound docking predictions, our method was able to find a near-native solution (interface C-αRMSD ≤ 2.5 Å within the top 1000 ranks. For unbound docking, among the 60 complexes for which our algorithm returned at least one hit, 60% of the cases were ranked within the top 2000. Comparison with existing shape-based docking algorithms shows that our method has a better performance than the others in unbound docking while remaining competitive for bound docking cases. Conclusion We show for the first time that the 3D Zernike descriptors are adept in capturing shape complementarity at the protein-protein interface and useful for

  2. Combinatorial aspects of covering arrays

    Directory of Open Access Journals (Sweden)

    Charles J. Colbourn

    2004-11-01

    Full Text Available Covering arrays generalize orthogonal arrays by requiring that t -tuples be covered, but not requiring that the appearance of t -tuples be balanced.Their uses in screening experiments has found application in software testing, hardware testing, and a variety of fields in which interactions among factors are to be identified. Here a combinatorial view of covering arrays is adopted, encompassing basic bounds, direct constructions, recursive constructions, algorithmic methods, and applications.

  3. Automatic Method to Classify Images Based on Multiscale Fractal Descriptors and Paraconsistent Logic

    Science.gov (United States)

    Pavarino, E.; Neves, L. A.; Nascimento, M. Z.; Godoy, M. F.; Arruda, P. F.; Neto, D. S.

    2015-01-01

    In this study is presented an automatic method to classify images from fractal descriptors as decision rules, such as multiscale fractal dimension and lacunarity. The proposed methodology was divided in three steps: quantification of the regions of interest with fractal dimension and lacunarity, techniques under a multiscale approach; definition of reference patterns, which are the limits of each studied group; and, classification of each group, considering the combination of the reference patterns with signals maximization (an approach commonly considered in paraconsistent logic). The proposed method was used to classify histological prostatic images, aiming the diagnostic of prostate cancer. The accuracy levels were important, overcoming those obtained with Support Vector Machine (SVM) and Best- first Decicion Tree (BFTree) classifiers. The proposed approach allows recognize and classify patterns, offering the advantage of giving comprehensive results to the specialists.

  4. Analysis of cancer cell morphology in fluorescence microscopy image exploiting shape descriptor

    Science.gov (United States)

    Kang, Mi-Sun; Kim, Hye-Ryun; Kim, Sudong; Ryu, Gyu Ha; Kim, Myoung-Hee

    2016-04-01

    Cancer cell morphology is closely related to their phenotype and activity. These characteristics are important in drug-response prediction for personalized cancer therapeutics. We used multi-channel fluorescence microscopy images to analyze the morphology of highly cohesive cancer cells. First, we detected individual nuclei regions in single-channel images using advanced simple linear iterative clustering. The center points of the nuclei regions were used as seeds for the Voronoi diagram method to extract spatial arrangement features from cell images. Human cancer cell populations form irregularly shaped aggregates, making their detection more difficult. We overcame this problem by identifying individual cells using an image-based shape descriptor. Finally, we analyzed the correlation between cell agglutination and cell shape.

  5. Dendritic cell recognition using template matching based on one-dimensional (1D) Fourier descriptors (FD)

    Science.gov (United States)

    Muhd Suberi, Anis Azwani; Wan Zakaria, Wan Nurshazwani; Tomari, Razali; Lau, Mei Xia

    2016-07-01

    Identification of Dendritic Cell (DC) particularly in the cancer microenvironment is a unique disclosure since fighting tumor from the harnessing immune system has been a novel treatment under investigation. Nowadays, the staining procedure in sorting DC can affect their viability. In this paper, a computer aided system is proposed for automatic classification of DC in peripheral blood mononuclear cell (PBMC) images. Initially, the images undergo a few steps in preprocessing to remove uneven illumination and artifacts around the cells. In segmentation, morphological operators and Canny edge are implemented to isolate the cell shapes and extract the contours. Following that, information from the contours are extracted based on Fourier descriptors, derived from one dimensional (1D) shape signatures. Eventually, cells are classified as DC by comparing template matching (TM) of established template and target images. The results show that the proposed scheme is reliable and effective to recognize DC.

  6. Prediction of liquid chromatography retention factors for α-branched phenylsulfonyl acetates using quantum chemical descriptors

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The logarithms of retention factors normalized to a hypothetical pure water eluent( log kw ) were determined on a reversed-phase highperformance liquid chromatography(RP-HPLC) column (Li Chrosorb RP-18 column) for 20 new α-branched phenylsulfonyl acetates. The atomic charge method was applied to develop quantitative structure-retention relationships (QSRRs). Among the available geometric and electronic descriptors, surface area (S), ovality (O), and the charge of carboxyl group(Qoc ) are significant. In the model, the contribution of surface area (S) is the greatest. The molecular mechanism of retention was demonstrated through the model. With the correlation coefficient ( r2adj, adjusted for degrees of freedom) of 0. 964, the standard error of 0. 164 and the F-value of 170.39, the model has good predictive capacity.

  7. Spectral descriptors for bulk metallic glasses based on the thermodynamics of competing crystalline phases

    CERN Document Server

    Perim, Eric; Liu, Yanhui; Toher, Cormac; Gong, Pan; Li, Yanglin; Simmons, W Neal; Levy, Ohad; Vlassak, Joost J; Schroers, Jan; Curtarolo, Stefano

    2016-01-01

    Metallic glasses have attracted considerable interest in recent years due to their unique combination of superb properties and processability. Predicting bulk metallic glass formers from known parameters remains a challenge and the search for new systems is still performed by trial and error. It has been speculated that some sort of "confusion" during crystallization of the crystalline phases competing with glass formation could play a key role. Here, we propose a heuristic descriptor quantifying confusion and demonstrate its validity by detailed experiments on two well-known glass forming alloy systems. With the insight provided by these results, we develop a robust model for predicting glass formation ability based on the spectral decomposition of geometrical and energetic features of crystalline phases calculated ab-initio in the AFLOW high throughput framework. Our findings indicate that the formation of metallic glass phases could be a much more common phenomenon than currently estimated, with more than ...

  8. A robust line matching method based on local appearance descriptor and neighboring geometric attributes

    Science.gov (United States)

    Xing, Jing; Wei, Zhenzhong; Zhang, Guangjun

    2016-10-01

    This paper reports an efficient method for line matching, which utilizes local intensity gradient information and neighboring geometric attributes. Lines are detected in a multi-scale way to make the method robust to scale changes. A descriptor based on local appearance is built to generate candidate matching pairs. The key idea is to accumulate intensity gradient information into histograms based on their intensity orders to overcome the fragmentation problem of lines. Besides, local coordinate system is built for each line to achieve rotation invariance. For each line segment in candidate matching pairs, a histogram is built by aggregating geometric attributes of neighboring line segments. The final matching measure derives from the distance between normalized geometric attributes histograms. Experiments show that the proposed method is robust to large illumination changes and is rotation invariant.

  9. Texture descriptors to distinguish radiation necrosis from recurrent brain tumors on multi-parametric MRI

    Science.gov (United States)

    Tiwari, Pallavi; Prasanna, Prateek; Rogers, Lisa; Wolansky, Leo; Badve, Chaitra; Sloan, Andrew; Cohen, Mark; Madabhushi, Anant

    2014-03-01

    Di erentiating radiation necrosis (a radiation induced treatment e ect) from recurrent brain tumors (rBT) is currently one of the most clinically challenging problems in care and management of brain tumor (BT) patients. Both radiation necrosis (RN), and rBT exhibit similar morphological appearance on standard MRI making non-invasive diagnosis extremely challenging for clinicians, with surgical intervention being the only course for obtaining de nitive ground truth". Recent studies have reported that the underlying biological pathways de n- ing RN and rBT are fundamentally di erent. This strongly suggests that there might be phenotypic di erences and hence cues on multi-parametric MRI, that can distinguish between the two pathologies. One challenge is that these di erences, if they exist, might be too subtle to distinguish by the human observer. In this work, we explore the utility of computer extracted texture descriptors on multi-parametric MRI (MP-MRI) to provide alternate representations of MRI that may be capable of accentuating subtle micro-architectural di erences between RN and rBT for primary and metastatic (MET) BT patients. We further explore the utility of texture descriptors in identifying the MRI protocol (from amongst T1-w, T2-w and FLAIR) that best distinguishes RN and rBT across two independent cohorts of primary and MET patients. A set of 119 texture descriptors (co-occurrence matrix homogeneity, neighboring gray-level dependence matrix, multi-scale Gaussian derivatives, Law features, and histogram of gradient orientations (HoG)) for modeling di erent macro and micro-scale morphologic changes within the treated lesion area for each MRI protocol were extracted. Principal component analysis based variable importance projection (PCA-VIP), a feature selection method previously developed in our group, was employed to identify the importance of every texture descriptor in distinguishing RN and rBT on MP-MRI. PCA-VIP employs regression analysis to provide

  10. Explaining reaction mechanisms using the dual descriptor: a complementary tool to the molecular electrostatic potential.

    Science.gov (United States)

    Martínez-Araya, Jorge Ignacio

    2013-07-01

    The intrinsic reactivity of cyanide when interacting with a silver cation was rationalized using the dual descriptor (DD) as a complement to the molecular electrostatic potential (MEP) in order to predict interactions at the local level. It was found that DD accurately explains covalent interactions that cannot be explained by MEP, which focuses on essentially ionic interactions. This allowed the rationalization of the reaction mechanism that yields silver cyanide in the gas phase. Other similar reaction mechanisms involving a silver cation interacting with water, ammonia, and thiosulfate were also explained by the combination of MEP and DD. This analysis provides another example of the usefulness of DD as a tool for gaining a deeper understanding of any reaction mechanism that is mainly governed by covalent interactions.

  11. Confidence level fusion of edge histogram descriptor, hidden Markov model, spectral correlation feature, and NUKEv6

    Science.gov (United States)

    Ho, K. C.; Gader, P. D.; Frigui, H.; Wilson, J. N.

    2007-04-01

    This paper examines the confidence level fusion of several promising algorithms for the vehiclemounted ground penetrating radar landmine detection system. The detection algorithms considered here include Edge Histogram Descriptor (EHD), Hidden Markov Model (HMM), Spectral Correlation Feature (SCF) and NUKEv6. We first form a confidence vector by collecting the confidence values from the four individual detectors. The fused confidence is assigned to be the difference in the square of the Mahalanobis distance to the non-mine class and the square of the Mahalanobis distance to the mine class. Experimental results on a data collection that contains over 1500 mine encounters indicate that the proposed fusion technique can reduce the false alarm rate by a factor of two at 90% probability of detection when compared to the best individual detector.

  12. Fractional Differential Texture Descriptors Based on the Machado Entropy for Image Splicing Detection

    Directory of Open Access Journals (Sweden)

    Rabha W. Ibrahim

    2015-07-01

    Full Text Available Image splicing is a common operation in image forgery. Different techniques of image splicing detection have been utilized to regain people’s trust. This study introduces a texture enhancement technique involving the use of fractional differential masks based on the Machado entropy. The masks slide over the tampered image, and each pixel of the tampered image is convolved with the fractional mask weight window on eight directions. Consequently, the fractional differential texture descriptors are extracted using the gray-level co-occurrence matrix for image splicing detection. The support vector machine is used as a classifier that distinguishes between authentic and spliced images. Results prove that the achieved improvements of the proposed algorithm are compatible with other splicing detection methods.

  13. Prediction of Protein-Protein Interactions with Physicochemical Descriptors and Wavelet Transform via Random Forests.

    Science.gov (United States)

    Jia, Jianhua; Xiao, Xuan; Liu, Bingxiang

    2016-06-01

    Protein-protein interactions (PPIs) provide valuable insight into the inner workings of cells, and it is significant to study the network of PPIs. It is vitally important to develop an automated method as a high-throughput tool to timely predict PPIs. Based on the physicochemical descriptors, a protein was converted into several digital signals, and then wavelet transform was used to analyze them. With such a formulation frame to represent the samples of protein sequences, the random forests algorithm was adopted to conduct prediction. The results on a large-scale independent-test data set show that the proposed model can achieve a good performance with an accuracy value of about 0.86 and a geometric mean value of about 0.85. Therefore, it can be a usefully supplementary tool for PPI prediction. The predictor used in this article is freely available at http://www.jci-bioinfo.cn/PPI_RF.

  14. {sup 13}C NMR spectral data and molecular descriptors to predict the antioxidant activity of flavonoids

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, Mariane Balerine; Muramatsu, Eric [Universidade de Sao Paulo (USP). Ribeirao Preto, SP (Brazil). Fac. de Ciencias Farmauceuticas; Emereciano, Vicente de Paula [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Quimica; Scotti, Marcus Tullius [Universidade Federal da Paraiba (UFPA), Joao Pessoa, PA (Brazil). Centro de Ciencias Aplicadas e Educacao; Scotti, Luciana; Tavares, Josean Fechine; Silva, Marcelo Sobral da [Universidade Federal da Paraiba (UFPA), Joao Pessoa, PA (Brazil). Lab. de Tecnologia Farmaceutica

    2011-04-15

    Tissue damage due to oxidative stress is directly linked to development of many, if not all, human morbidity factors and chronic diseases. In this context, the search for dietary natural occurring molecules with antioxidant activity, such as flavonoids, has become essential. In this study, we investigated a set of 41 flavonoids (23 flavones and 18 flavonols) analyzing their structures and biological antioxidant activity. The experimental data were submitted to a QSAR (quantitative structure-activity relationships) study. NMR {sup 13}C data were used to perform a Kohonen self-organizing map study, analyzing the weight that each carbon has in the activity. Additionally, we performed MLR (multilinear regression) using GA (genetic algorithms) and molecular descriptors to analyze the role that specific carbons and substitutions play in the activity. (author)

  15. Quantitative structure-activity relationships of selective antagonists of glucagon receptor using QuaSAR descriptors.

    Science.gov (United States)

    Manoj Kumar, Palanivelu; Karthikeyan, Chandrabose; Hari Narayana Moorthy, Narayana Subbiah; Trivedi, Piyush

    2006-11-01

    In the present paper, quantitative structure activity relationship (QSAR) approach was applied to understand the affinity and selectivity of a novel series of triaryl imidazole derivatives towards glucagon receptor. Statistically significant and highly predictive QSARs were derived for glucagon receptor inhibition by triaryl imidazoles using QuaSAR descriptors of molecular operating environment (MOE) employing computer-assisted multiple regression procedure. The generated QSAR models revealed that factors related to hydrophobicity, molecular shape and geometry predominantly influences glucagon receptor binding affinity of the triaryl imidazoles indicating the relevance of shape specific steric interactions between the molecule and the receptor. Further, QSAR models formulated for selective inhibition of glucagon receptor over p38 mitogen activated protein (MAP) kinase of the compounds in the series highlights that the same structural features, which influence the glucagon receptor affinity, also contribute to their selective inhibition.

  16. Transferring Instantly the State of Higher-Order Linear Descriptor (Regular Differential Systems Using Impulsive Inputs

    Directory of Open Access Journals (Sweden)

    Athanasios D. Karageorgos

    2009-01-01

    Full Text Available In many applications, and generally speaking in many dynamical differential systems, the problem of transferring the initial state of the system to a desired state in (almost zero-time time is desirable but difficult to achieve. Theoretically, this can be achieved by using a linear combination of Dirac -function and its derivatives. Obviously, such an input is physically unrealizable. However, we can think of it approximately as a combination of small pulses of very high magnitude and infinitely small duration. In this paper, the approximation process of the distributional behaviour of higher-order linear descriptor (regular differential systems is presented. Thus, new analytical formulae based on linear algebra methods and generalized inverses theory are provided. Our approach is quite general and some significant conditions are derived. Finally, a numerical example is presented and discussed.

  17. Quality descriptors of optical beams based on centred reduced moments I spot analysis

    CERN Document Server

    Castaneda, R; García-Sucerquia, J

    2003-01-01

    A method for analyzing beam spots is discussed. It is based on the central reduced moments of the spot and its associated density functions. These functions allow us to separately analyze specific spot fractions, in such a way that specific combinations of higher order moments can be interpreted as coordinates of their centre of mass and the length and orientations of their principal axis. So, the descriptors of the associated density functions deal with the quantitative estimation of spot features, such as coma-like and astigmatism-like distortions. To assure high accuracy, background noise suppression and an optimal match of the spot support onto the region [-1,1]x[- 1,1] are performed prior to the calculation of the moments. Simulations were performed for illustrating the method.

  18. Prioritization of in silico models and molecular descriptors for the assessment of ready biodegradability.

    Science.gov (United States)

    Fernández, Alberto; Rallo, Robert; Giralt, Francesc

    2015-10-01

    Ready biodegradability is a key property for evaluating the long-term effects of chemicals on the environment and human health. As such, it is used as a screening test for the assessment of persistent, bioaccumulative and toxic substances. Regulators encourage the use of non-testing methods, such as in silico models, to save money and time. A dataset of 757 chemicals was collected to assess the performance of four freely available in silico models that predict ready biodegradability. They were applied to develop a new consensus method that prioritizes the use of each individual model according to its performance on chemical subsets driven by the presence or absence of different molecular descriptors. This consensus method was capable of almost eliminating unpredictable chemicals, while the performance of combined models was substantially improved with respect to that of the individual models.

  19. What makes a good descriptor for heterogeneous ice nucleation on OH-patterned surfaces

    Science.gov (United States)

    Pedevilla, Philipp; Fitzner, Martin; Michaelides, Angelos

    2017-09-01

    Freezing of water is arguably one of the most common phase transitions on Earth and almost always happens heterogeneously. Despite its importance, we lack a fundamental understanding of what makes substrates efficient ice nucleators. Here we address this by computing the ice nucleation (IN) ability of numerous model hydroxylated substrates with diverse surface hydroxyl (OH) group arrangements. Overall, for the substrates considered, we find that neither the symmetry of the OH patterns nor the similarity between a substrate and ice correlate well with the IN ability. Instead, we find that the OH density and the substrate-water interaction strength are useful descriptors of a material's IN ability. This insight allows the rationalization of ice nucleation ability across a wide range of materials and can aid the search and design of novel potent ice nucleators in the future.

  20. Bottlenecks in the prediction of regioselectivity of [4 + 2] cycloaddition reactions: An assessment of reactivity descriptors

    Indian Academy of Sciences (India)

    G Gayatri; G Narahari Sastry

    2005-09-01

    B3LYP/6-31G() calculations were performed to obtain all the transition states and products for the 128 distinct reaction channels of Diels-Alder reactions by taking all possible combinations from a series of dienes (1N-a, 1N-b, 2N, 1P-a, 1P-b, 2P, 1O, 1S) and dienophiles (NE, PE, OE, SE, AE, OHE, MeE, CNE). The predictive ability of the values to gauge the regioselectivity of the putative [4 + 2] cycloaddition reactions is analysed. No correlation is obtained between the reaction energies and activation energies. The extent of asynchronicity is measured based on the bond order analysis. DFT-based descriptors such as the local softness ($s^{+}_{k}$ and $s_{k}^{-}$), Fukui function indices ($f^{+}_{k}$ and $f_{k}^{-}$), global electrophilicity index () and local electrophilicity index () were found to be better than the conventional FMO predictions.

  1. Hyper-spectral image segmentation using spectral clustering with covariance descriptors

    Science.gov (United States)

    Kursun, Olcay; Karabiber, Fethullah; Koc, Cemalettin; Bal, Abdullah

    2009-02-01

    Image segmentation is an important and difficult computer vision problem. Hyper-spectral images pose even more difficulty due to their high-dimensionality. Spectral clustering (SC) is a recently popular clustering/segmentation algorithm. In general, SC lifts the data to a high dimensional space, also known as the kernel trick, then derive eigenvectors in this new space, and finally using these new dimensions partition the data into clusters. We demonstrate that SC works efficiently when combined with covariance descriptors that can be used to assess pixelwise similarities rather than in the high-dimensional Euclidean space. We present the formulations and some preliminary results of the proposed hybrid image segmentation method for hyper-spectral images.

  2. Five-descriptor model to predict the chromatographic sequence of natural compounds.

    Science.gov (United States)

    Hou, Shuying; Wang, Jinhua; Li, Zhangming; Wang, Yang; Wang, Ying; Yang, Songling; Xu, Jia; Zhu, Wenliang

    2016-03-01

    Despite the recent introduction of mass detection techniques, ultraviolet detection is still widely applied in the field of the chromatographic analysis of natural medicines. Here, a neural network cascade model consisting of nine small artificial neural network units was innovatively developed to predict the chromatographic sequence of natural compounds by integrating five molecular descriptors as the input. A total of 117 compounds of known structure were collected for model building. The order of appearance of each compound was determined in gradient chromatography. Strong linear correlation was found between the predicted and actual chromatographic position orders (Spearman's rho = 0.883, p chromatographic order of multiple compounds. A case study shows that chromatographic sequence prediction based on a neural network cascade facilitated compound identification in the chromatographic fingerprint of Radix Salvia miltiorrhiza. For natural medicines of known compound composition, our method provides a feasible means for identifying the constituents of interest when only ultraviolet detection is available.

  3. Assessment of Food and Nutrition Related Descriptors in Agricultural and Biomedical Thesauri

    Science.gov (United States)

    Bartol, Tomaz

    Food- and human nutrition-related subject headings or descriptors of the following thesauri-databases are assessed: NAL Thesaurus/Agricola, Agrovoc/Agris, CAB Thesaurus, FSTA Thesaurus, MeSH/Medline. Food concepts can be represented by thousands of different terms but subject scope of a particular term is sometimes vague. There exist important differences among thesauri regarding same or similar concept. A term that represents narrower or broader concept in one thesaurus can in another stand for a related concept or be non-existent. Sometimes there is no clear implication of differences between scientific (Latin) and common (English) names. Too many related terms can confuse end-users. Thesauri were initially employed mostly by information professionals but can now be used directly by users who may be unaware of differences. Thesauri are assuming new roles in classification of information as metadata. Further development towards ontologies must pay constant attention to taxonomic problems of representation of knowledge.

  4. GLOBAL AND LOCAL REACTIVITY DESCRIPTORS FOR PICLORAM HERBICIDE: A THEORETICAL QUANTUM STUDY

    Directory of Open Access Journals (Sweden)

    Luis H. Mendoza-Huizar

    2015-01-01

    Full Text Available In this work, we studied the reactivity of picloram in the aqueous phase at the B3LYP/6-311++G(2d,2p and MP2/6-311++G(2d,2p levels of theory through global and local reactivity descriptors. The results obtained at the MP2 level indicate that the cationic form of picloram exhibits the highest hardness while the anionic form is the most nucleophilic. From the Fukui function values, the most reactive site for electrophilic and free radical attacks are on the nitrogen in the pyridine ring. The more reactive sites for nucleophilic attacks are located on the nitrogen atom of the amide group and on the carbon atoms located at positions 2 and 3 in the pyridine ring.

  5. Categorical dimensions of human odor descriptor space revealed by non-negative matrix factorization

    Energy Technology Data Exchange (ETDEWEB)

    Chennubhotla, Chakra [University of Pittsburgh School of Medicine, Pittsburgh PA; Castro, Jason [Bates College

    2013-01-01

    In contrast to most other sensory modalities, the basic perceptual dimensions of olfaction remain un- clear. Here, we use non-negative matrix factorization (NMF) - a dimensionality reduction technique - to uncover structure in a panel of odor profiles, with each odor defined as a point in multi-dimensional descriptor space. The properties of NMF are favorable for the analysis of such lexical and perceptual data, and lead to a high-dimensional account of odor space. We further provide evidence that odor di- mensions apply categorically. That is, odor space is not occupied homogenously, but rather in a discrete and intrinsically clustered manner. We discuss the potential implications of these results for the neural coding of odors, as well as for developing classifiers on larger datasets that may be useful for predicting perceptual qualities from chemical structures.

  6. Is electronegativity a useful descriptor for the pseudo-alkali metal NH4?

    Science.gov (United States)

    Whiteside, Alexander; Xantheas, Sotiris S; Gutowski, Maciej

    2011-11-18

    Molecular ions in the form of "pseudo-atoms" are common structural motifs in chemistry, with properties that are transferrable between different compounds. We have determined one such property--the electronegativity--for the "pseudo-alkali metal" ammonium (NH(4)), and evaluated its reliability as a descriptor versus the electronegativities of the alkali metals. The computed properties of ammonium's binary complexes with astatine and of selected borohydrides confirm the similarity of NH(4) to the alkali metal atoms, although the electronegativity of NH(4) is relatively large in comparison to its cationic radius. We have paid particular attention to the molecular properties of ammonium (angular anisotropy, geometric relaxation and reactivity), which can cause deviations from the behaviour expected of a conceptual "true alkali metal" with this electronegativity. These deviations allow for the discrimination of effects associated with the molecular nature of NH(4).

  7. Local self-similarity descriptor for point-of-interest reconstruction of real-world scenes

    Science.gov (United States)

    Gao, Xianglu; Wan, Weibing; Zhao, Qunfei; Zhang, Xianmin

    2015-08-01

    Scene reconstruction is utilized commonly in close-range photogrammetry, with diverse applications in fields such as industry, biology, and aerospace industries. Presented surfaces or wireframe three-dimensional (3D) model reconstruction applications are either too complex or too inflexible to accommodate various types of real-world scenes, however. This paper proposes an algorithm for acquiring point-of-interest (referred to throughout the study as POI) coordinates in 3D space, based on multi-view geometry and a local self-similarity descriptor. After reconstructing several POIs specified by a user, a concise and flexible target object measurement method, which obtains the distance between POIs, is described in detail. The proposed technique is able to measure targets with high accuracy even in the presence of obstacles and non-Lambertian surfaces. The method is so flexible that target objects can be measured with a handheld digital camera. Experimental results further demonstrate the effectiveness of the algorithm.

  8. Robust Stabilization of T-S Fuzzy Stochastic Descriptor Systems via Integral Sliding Modes.

    Science.gov (United States)

    Li, Jinghao; Zhang, Qingling; Yan, Xing-Gang; Spurgeon, Sarah K

    2017-09-19

    This paper addresses the robust stabilization problem for T-S fuzzy stochastic descriptor systems using an integral sliding mode control paradigm. A classical integral sliding mode control scheme and a nonparallel distributed compensation (Non-PDC) integral sliding mode control scheme are presented. It is shown that two restrictive assumptions previously adopted developing sliding mode controllers for Takagi-Sugeno (T-S) fuzzy stochastic systems are not required with the proposed framework. A unified framework for sliding mode control of T-S fuzzy systems is formulated. The proposed Non-PDC integral sliding mode control scheme encompasses existing schemes when the previously imposed assumptions hold. Stability of the sliding motion is analyzed and the sliding mode controller is parameterized in terms of the solutions of a set of linear matrix inequalities which facilitates design. The methodology is applied to an inverted pendulum model to validate the effectiveness of the results presented.

  9. Descriptors and Thermodynamic Limitations of Electrocatalytic Carbon Dioxide Reduction on Rutile Oxide Surfaces

    DEFF Research Database (Denmark)

    Bhowmik, Arghya; Vegge, Tejs; Hansen, Heine Anton

    2016-01-01

    and it defines the left leg of the activity volcano for CO2RR. HCOOH* is a key intermediate for products formed through further reduction, for example, methanediol, methanol, and methane. The surfaces that do not bind HCOOH* are selective towards formic acid (HCOOH) production, but hydrogen evolution limits......A detailed understanding of the electrochemical reduction of CO2 into liquid fuels on rutile metal oxide surfaces is developed by using DFT calculations. We consider oxide overlayer structures on RuO2(1 1 0) surfaces as model catalysts to elucidate the trends and limitations in the CO2 reduction...... reaction (CO2RR) based on thermodynamic analysis. We aim to specify the requirements for CO2RR catalysts to establish adsorbate scaling relations and use these to derive activity volcanoes. Computational results show that the OH* binding free energy is a good descriptor of the thermodynamic limitations...

  10. Iris Segmentation using Gradient Magnitude and Fourier Descriptor for Multimodal Biometric Authentication System

    Directory of Open Access Journals (Sweden)

    Defiana Sulaeman

    2016-12-01

    Full Text Available Perfectly segmenting the area of the iris is one of the most important steps in iris recognition. There are several problematic areas that affect the accuracy of the iris segmentation step, such as eyelids, eyelashes, glasses, pupil (due to less accurate iris segmentation, motion blur, and lighting and specular reflections. To solve these problems, gradient magnitude and Fourier descriptor are employed to do iris segmentation in the proposed Multimodal Biometric Authentication System (MBAS. This approach showed quite promising results, i.e. an accuracy rate of 97%. The result of the iris recognition system was combined with the result of an open-source fingerprint recognition system to develop a multimodal biometrics authentication system. The results of the fusion between iris and fingerprint authentication were 99% accurate. Data from Multimedia Malaysia University (MMUI and our own prepared database, the SGU-MB-1 dataset, were used to test the accuracy of the proposed system.

  11. A PLS QSAR analysis using 3D generated aromatic descriptors of principal property type: Application to some dopamine D2 benzamide antagonists

    Science.gov (United States)

    Norinder, Ulf

    1993-12-01

    A simple and computationally nonintensive technique based on principal component analysis of 3D fields to derive theoretical descriptors is presented. The descriptors are then applied to a quantitative structure-activity relationship study on some dopamine D2 antagonists of benzamide type.

  12. GENETIC DIVERSITY IN ACCESSIONS OF Passiflora cincinnata Mast. BASED ON MORPHOAGRONOMIC DESCRIPTORS AND MOLECULAR MARKERS

    Directory of Open Access Journals (Sweden)

    TIAGO VINÍCIUS BATISTA DO CARMO

    2017-01-01

    Full Text Available Passiflora cincinnata Mast. has become more popular in the market because the unusual flavor of its fruits and natural beauty of its flowers, and has great potential for breeding programs of Passiflora edulis f. flavicarpa, because its resistance to diseases and drought. The objective of this work was to evaluate seven wild passion fruit (P. cincinnata accessions, using morphological and agronomic descriptors and molecular markers type ISSR, to identify their morphoagronomic and genetic variabilities and potential for use in breeding programs. A randomized block experimental design was used with five replications and two plants per plot. Thirteen qualitative and twenty-one quantitative, vegetative and floral characteristics were used for morphoagronomic characterization. Twelve ISSR primers were evaluated for molecular characterization. Among the qualitative characteristics, only the color variations were significantly different between the accessions. According to the mean squares of the quantitative characteristics evaluated, obtained from analysis of variance, the means of accessions showed significant differences (p<0.01 for all characteristics. The IAL (internode average length was the morphological descriptor that most contributed to diversity, with 43.12%, followed by DH5 (stem diameter at 5 cm height and SW (sepal width. The average genetic similarity found was 68%. Despite the low genetic variability found among accessions, the primers UBC-887 and UBC-841 stood out with high percentage of polymorphism with 14 and 11 polymorphic fragments, respectively, and higher values of polymorphism information content (PIC, resolving power (RP and marker index (MI, denoting suitability for use in diversity studies of P. cincinnata. Low variability was found among accessions evaluated.

  13. Prediction of monomer reactivity in radical copolymerizations from transition state quantum chemical descriptors

    Directory of Open Access Journals (Sweden)

    Zhengde Tan

    2013-01-01

    Full Text Available In comparison with the Q-e scheme, the Revised Patterns Scheme: the U, V Version (the U-V scheme has greatly improved both its accessibility and its accuracy in interpreting and predicting the reactivity of a monomer in free-radical copolymerizations. Quantitative structure-activity relationship (QSAR models were developed to predict the reactivity parameters u and v of the U-V scheme, by applying genetic algorithm (GA and support vector machine (SVM techniques. Quantum chemical descriptors used for QSAR models were calculated from transition state species with structures C¹H3 - C²HR³• or •C¹H2 - C²H2R³ (formed from vinyl monomers C¹H²=C²HR³ + H•, using density functional theory (DFT, at the UB3LYP level of theory with 6-31G(d basis set. The optimum support vector regression (SVR model of the reactivity parameter u based on Gaussian radial basis function (RBF kernel (C = 10, ε = 10- 5 and γ = 1.0 produced root-mean-square (rms errors for the training, validation and prediction sets being 0.220, 0.326 and 0.345, respectively. The optimal SVR model for v with the RBF kernel (C = 20, ε = 10- 4 and γ = 1.2 produced rms errors for the training set of 0.123, the validation set of 0.206 and the prediction set of 0.238. The feasibility of applying the transition state quantum chemical descriptors to develop SVM models for reactivity parameters u and v in the U-V scheme has been demonstrated.

  14. CORAL Software: Analysis of Impacts of Pharmaceutical Agents Upon Metabolism via the Optimal Descriptors.

    Science.gov (United States)

    Toropova, Mariya A; Raska, Ivan; Toporova, Alla P; Raskova, Maria

    2017-01-01

    The CORAL software has been developed as a tool to build up quantitative structure- activity relationships (QSAR) for various endpoints. The task of the present work was to estimate and to compare QSAR models for biochemical activity of various therapeutic agents, which are built up by the CORAL software. The Monte Carlo technique gives possibility to build up predictive model of an endpoint by means of selection of so-called correlation weights of various molecular features extracted from simplified molecular input-line entry system (SMILES). Descriptors calculated with these weights are basis for building up correlations "structure - endpoint". Optimal descriptors, which are aimed to predict values of endpoints with apparent influence upon metabolism are crytically compared in aspect of their robustness and heuristic potential. Arguments which are confirming the necessity of reformulation of basics of QSARs are listed: (i) each QSAR model is stochastic experiment. The result of this experiment is defined by distribution into the training set and validation set; (ii) predictive potential of a model should be checked up with a group of different splits; and (iii) only model stochastically stable for a group of splits can be estimated as a reliable tool for the prediction. Examples of the improvement of the models previously suggested are demonstrated. The current version of the CORAL software remains a convenient tool to build up predictive models. The Monte Carlo technique involved for the software confirms the principle "QSAR is a random event" is important paradigm for the QSPR/QSAR analyses. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  15. Solution Properties of Linear Descriptor (Singular Matrix Differential Systems of Higher Order with (Non- Consistent Initial Conditions

    Directory of Open Access Journals (Sweden)

    Athanasios A. Pantelous

    2010-01-01

    Full Text Available In some interesting applications in control and system theory, linear descriptor (singular matrix differential equations of higher order with time-invariant coefficients and (non- consistent initial conditions have been used. In this paper, we provide a study for the solution properties of a more general class of the Apostol-Kolodner-type equations with consistent and nonconsistent initial conditions.

  16. Descriptor-variable approach to modeling and optimization of large-scale systems. Final report, March 1976--February 1979

    Energy Technology Data Exchange (ETDEWEB)

    Stengel, D N; Luenberger, D G; Larson, R E; Cline, T B

    1979-02-01

    A new approach to modeling and analysis of systems is presented that exploits the underlying structure of the system. The development of the approach focuses on a new modeling form, called 'descriptor variable' systems, that was first introduced in this research. Key concepts concerning the classification and solution of descriptor-variable systems are identified, and theories are presented for the linear case, the time-invariant linear case, and the nonlinear case. Several standard systems notions are demonstrated to have interesting interpretations when analyzed via descriptor-variable theory. The approach developed also focuses on the optimization of large-scale systems. Descriptor variable models are convenient representations of subsystems in an interconnected network, and optimization of these models via dynamic programming is described. A general procedure for the optimization of large-scale systems, called spatial dynamic programming, is presented where the optimization is spatially decomposed in the way standard dynamic programming temporally decomposes the optimization of dynamical systems. Applications of this approach to large-scale economic markets and power systems are discussed.

  17. Are tags from Mars and descriptors from Venus? A study on the ecology of educational resource metadata

    NARCIS (Netherlands)

    Vuorikari, Riina; Sillaots, Martin; Panzavolta, Silvia; Koper, Rob

    2009-01-01

    Vuorikari, R., Sillaots, M., Panzavolta, S. & Koper, R. (2009). Are tags from Mars and descriptors from Venus? A study on the ecology of educational resource metadata. In M. Spaniol, Q. Li, R. Klamma & R. W. H. Lau (Eds.), Proceedings of the 8th International Conference Advances in Web Based Learnin

  18. Periodic table-based descriptors to encode cytotoxicity profile of metal oxide nanoparticles: a mechanistic QSTR approach.

    Science.gov (United States)

    Kar, Supratik; Gajewicz, Agnieszka; Puzyn, Tomasz; Roy, Kunal; Leszczynski, Jerzy

    2014-09-01

    Nanotechnology has evolved as a frontrunner in the development of modern science. Current studies have established toxicity of some nanoparticles to human and environment. Lack of sufficient data and low adequacy of experimental protocols hinder comprehensive risk assessment of nanoparticles (NPs). In the present work, metal electronegativity (χ), the charge of the metal cation corresponding to a given oxide (χox), atomic number and valence electron number of the metal have been used as simple molecular descriptors to build up quantitative structure-toxicity relationship (QSTR) models for prediction of cytotoxicity of metal oxide NPs to bacteria Escherichia coli. These descriptors can be easily obtained from molecular formula and information acquired from periodic table in no time. It has been shown that a simple molecular descriptor χox can efficiently encode cytotoxicity of metal oxides leading to models with high statistical quality as well as interpretability. Based on this model and previously published experimental results, we have hypothesized the most probable mechanism of the cytotoxicity of metal oxide nanoparticles to E. coli. Moreover, the required information for descriptor calculation is independent of size range of NPs, nullifying a significant problem that various physical properties of NPs change for different size ranges. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. A novel QSPR study of normalized migration time for drugs in capillary electrophoresis by new descriptors: quantum chemical investigation.

    Science.gov (United States)

    Riahi, Siavash; Beheshti, Abolghasem; Ganjali, Mohammad Reza; Norouzi, Parviz

    2008-10-01

    Some drugs' migration time (MT) has been studied employing quantitative structure-property relationship using new descriptors that are able to predict MT value with high accuracy. MT property modeling of the drugs was established as a function of the new theoretically derived descriptors applying multiple linear regressions and partial least-squares regression. The genetic algorithm was used to select those variables that resulted in the best-fitted models. To select a set of descriptors that are most relevant to MT, illustrating the affecting degree for the affinity of different descriptors, the linear models with 1-14 variables were constructed and were then investigated based on F-value, squared regression coefficients of cross-validated (Q2), adjusted R2 (R2adj) and standard error of estimate (S) statistical parameters. Finally, the best model with ten variables was selected. Statistical parameters of the test set, such as standard deviation error in test, were 0.559 and 0.616, while relative error of test was equal to 7.648 and 8.497% for multiple linear regressions and partial least-squares models, respectively, confirming the good predictive ability of the model. Since the capillary lengths were not the same for the drugs in the data set, MT values were normalized based on a specific capillary before modeling, which is also one of the advantages of this method, enabling us to use the model for different capillary lengths.

  20. Statistical region based active contour using a fractional entropy descriptor: Application to nuclei cell segmentation in confocal \\ud microscopy images

    OpenAIRE

    Histace, A.; Meziou, B J; Matuszewski, Bogdan; Precioso, F.; Murphy, M F; Carreiras, F

    2013-01-01

    We propose an unsupervised statistical region based active contour approach integrating an original fractional entropy measure for image segmentation with a particular application to single channel actin tagged fluorescence confocal microscopy image segmentation. Following description of statistical based active contour segmentation and the mathematical definition of the proposed fractional entropy descriptor, we demonstrate comparative segmentation results between the proposed approach and s...

  1. QSAR modeling of toxicity of diverse organic chemicals to Daphnia magna using 2D and 3D descriptors

    Energy Technology Data Exchange (ETDEWEB)

    Kar, Supratik [Drug Theoretics and Cheminformatics Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Raja S C Mullick Road, Kolkata 700032 (India); Roy, Kunal, E-mail: kunalroy_in@yahoo.com [Drug Theoretics and Cheminformatics Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Raja S C Mullick Road, Kolkata 700032 (India)

    2010-05-15

    One of the major economic alternatives to experimental toxicity testing is the use of quantitative structure-activity relationships (QSARs) which are used in formulating regulatory decisions of environmental protection agencies. In this background, we have modeled a large diverse group of 297 chemicals for their toxicity to Daphnia magna using mechanistically interpretable descriptors. Three-dimensional (3D) (electronic and spatial) and two-dimensional (2D) (topological and information content indices) descriptors along with physicochemical parameter log K{sub o/w} (n-octanol/water partition coefficient) and structural descriptors were used as predictor variables. The QSAR models were developed by stepwise multiple linear regression (MLR), partial least squares (PLS), genetic function approximation (GFA), and genetic PLS (G/PLS). All the models were validated internally and externally. Among several models developed using different chemometric tools, the best model based on both internal and external validation characteristics was a PLS equation with 7 descriptors and three latent variables explaining 67.8% leave-one-out predicted variance and 74.1% external predicted variance. The PLS model suggests that higher lipophilicity and electrophilicity, less negative charge surface area and presence of ether linkage, hydrogen bond donor groups and acetylenic carbons are responsible for greater toxicity of chemicals. The developed model may be used for prediction of toxicity, safety and risk assessment of chemicals to achieve better ecotoxicological management and prevent adverse health consequences.

  2. Theoretical molecular descriptors relevant to the uptake of persistent organic pollutants from soil by zucchini. A QSAR study.

    Science.gov (United States)

    Bordás, Barna; Bélai, Iván; Koomíves, Tamás

    2011-04-13

    The uptake of persistent organic pollutants (POPs) from soil by plants allows the development of phytoremediation protocols to rehabilitate contaminated areas. The use of diverse theoretical descriptors has been reported in the literature for developing quantitative structure-activity relationship (QSAR) models for predicting the bioconcentration factors (BCFs) of POPs in different plants. In this paper an evaluation is given on the molecular properties of POPs in terms of theoretical molecular descriptors that are relevant to the uptake and accumulation of these persistent pollutants from soil by two zucchini varieties. Statistically significant and predictive linear regression models have been developed for the BCF values of 20 polychlorinated dibenzo-p-dioxins/dibenzofurans and 14 polyhalogenated biphenyls in two zucchini varieties based on retrospective data. The relevant parameters have been selected from a set of 1660 DRAGON, 150 VolSurf, and 11 quantum chemical descriptors. The two most significant regression models, containing VolSurf, DRAGON GETAWAY, and quantum chemical descriptors, displayed the following statistical parameters: (eq 3) n = 27, R(2) = 0.940, q(2) = 0.922, SE = 0.155, F = 392.1; (eq 4) n = 27, R(2) = 0.921, q(2) = 0.898, SE = 0.161, F = 140.4. Predictive capabilities of the equations have been validated by using external validation sets. The QSAR models proposed might contribute to the development of viable soil remediation strategies.

  3. The application of new HARD-descriptor available from the CORAL software to building up NOAEL models.

    Science.gov (United States)

    Toropova, Alla P; Toropov, Andrey A; Marzo, Marco; Escher, Sylvia E; Dorne, Jean Lou; Georgiadis, Nikolaos; Benfenati, Emilio

    2017-03-30

    Continuous QSAR models have been developed and validated for the prediction of no-observed-adverse-effect (NOAEL) in rats, using training and test sets from the Fraunhofer RepDose® database and EFSA's Chemical Hazards Database: OpenFoodTox. This paper demonstrates that the HARD index, as an integrated attribute of SMILES, improves the prediction power of NOAEL values using the continuous QSAR models and Monte Carlo simulations. The HARD-index is a line of eleven symbols, which represents the presence, or absence of eight chemical elements (nitrogen, oxygen, sulfur, phosphorus, fluorine, chlorine, bromine, and iodine) and different kinds of chemical bonds (double bond, triple bond, and stereo chemical bond). Optimal molecular descriptors calculated with the Monte Carlo technique (maximization of correlation coefficient between the descriptor and endpoint) give satisfactory predictive models for NOAEL. Optimal molecular descriptors calculated in this way with the Monte Carlo technique (maximization of correlation coefficient between the descriptor and endpoint) give amongst the best results available in the literature. The models are built up in accordance with OECD principles. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. In silico modelling of permeation enhancement potency in Caco-2 monolayers based on molecular descriptors and random forest

    DEFF Research Database (Denmark)

    Welling, Søren Havelund; Clemmensen, Line Katrine Harder; Buckley, Stephen T.

    2015-01-01

    has been developed.The random forest-QSAR model was based upon Caco-2 data for 41 surfactant-like permeation enhancers from Whitehead et al. (2008) and molecular descriptors calculated from their structure.The QSAR model was validated by two test-sets: (i) an eleven compound experimental set with Caco...

  5. Dualities in Covering Rough Operations

    Institute of Scientific and Technical Information of China (English)

    William Zhu

    2006-01-01

    Rough set theory is a technique of granular computing. In this paper, we study a type of generalized rough sets based on covering. There are several literatures[ 1,40-43 ] exploring covering-based rough sets. Our focus of this paper is on the dualities in rough operations.

  6. High plains cover crop research

    Science.gov (United States)

    Some recent statements have been made about the benefits of growing cover crops in mixtures as compared with single-species plantings of cover crops. Those stated benefits have included greatly reduced water use, enhanced soil microbiological activity, increased biomass productivity, and enhanced wa...

  7. Midwest Cover Crops Field Guide

    Science.gov (United States)

    Producers who want to prevent soil erosion, improve nutrient cycling, sustain their soils, and protect/maintain the environment have been returning to a very old practice: planting cover crops. Cover crops are effective tools for reducing soil erosion and increasing nutrient recycling on farmlands, ...

  8. Automatic design of magazine covers

    Science.gov (United States)

    Jahanian, Ali; Liu, Jerry; Tretter, Daniel R.; Lin, Qian; Damera-Venkata, Niranjan; O'Brien-Strain, Eamonn; Lee, Seungyon; Fan, Jian; Allebach, Jan P.

    2012-03-01

    In this paper, we propose a system for automatic design of magazine covers that quantifies a number of concepts from art and aesthetics. Our solution to automatic design of this type of media has been shaped by input from professional designers, magazine art directors and editorial boards, and journalists. Consequently, a number of principles in design and rules in designing magazine covers are delineated. Several techniques are derived and employed in order to quantify and implement these principles and rules in the format of a software framework. At this stage, our framework divides the task of design into three main modules: layout of magazine cover elements, choice of color for masthead and cover lines, and typography of cover lines. Feedback from professional designers on our designs suggests that our results are congruent with their intuition.

  9. Correlating toxicological effects of ionic liquids on Daphnia magna with in silico calculated linear free energy relationship descriptors.

    Science.gov (United States)

    Cho, Chul-Woong; Yun, Yeoung-Sang

    2016-06-01

    In silico prediction model for toxicological effects of ionic liquids (ILs) is useful to understand ILs' toxicological interactions and to design environmentally benign IL structures. Actually, it is essential since the types of ILs are extremely numerous. Accordingly, prediction models were developed in this study. For the modelling, well-defined linear free energy relationship (LFER) descriptors - i.e. excess molar refraction (E), dipolarity/polarizability (S), H-bonding acidity (A), H-bonding basicity (B), McGowan volume (V), cation interaction (J(+)) and anion interaction (J(-)) - were in silico calculated using density functional theory and conductor-like screening model. These descriptors were then correlated with the toxicological values of ILs to Daphnia magna. First, a model established by Hoover et al. (2007) using measured LFER descriptors of 97 neutral compounds was applied to the prediction of ILs' toxicity. As expected, the model by Hoover et al. (2007) needs to be amended for ILs. To that end, the difference in toxicological interactions between neutral compounds and ILs was addressed by additional single J(+) or five LFER descriptors of cation i.e. Ec, Sc, Bc, Vc, and J(+). Secondly, a prediction model for only ILs was developed by using the three LFER descriptors Ec, Bc, and J(+). The model had a reasonable predictability and robustness of R(2) = 0.880 for the training set, 0.848 for the test set, and 0.867 for the overall set. The established models can be used to design environmentally benign IL structures and to reduce labour, danger, time, and materials compared to the experiment-based study.

  10. Self-organizing maps of molecular descriptors for sesquiterpene lactones and their application to the chemotaxonomy of the Asteraceae family.

    Science.gov (United States)

    Scotti, Marcus T; Emerenciano, Vicente; Ferreira, Marcelo J P; Scotti, Luciana; Stefani, Ricardo; da Silva, Marcelo S; Mendonça Junior, Francisco Jaime B

    2012-04-20

    The Asteraceae, one of the largest families among angiosperms, is chemically characterised by the production of sesquiterpene lactones (SLs). A total of 1,111 SLs, which were extracted from 658 species, 161 genera, 63 subtribes and 15 tribes of Asteraceae, were represented and registered in two dimensions in the SISTEMATX, an in-house software system, and were associated with their botanical sources. The respective 11 block of descriptors: Constitutional, Functional groups, BCUT, Atom-centred, 2D autocorrelations, Topological, Geometrical, RDF, 3D-MoRSE, GETAWAY and WHIM were used as input data to separate the botanical occurrences through self-organising maps. Maps that were generated with each descriptor divided the Asteraceae tribes, with total index values between 66.7% and 83.6%. The analysis of the results shows evident similarities among the Heliantheae, Helenieae and Eupatorieae tribes as well as between the Anthemideae and Inuleae tribes. Those observations are in agreement with systematic classifications that were proposed by Bremer, which use mainly morphological and molecular data, therefore chemical markers partially corroborate with these classifications. The results demonstrate that the atom-centred and RDF descriptors can be used as a tool for taxonomic classification in low hierarchical levels, such as tribes. Descriptors obtained through fragments or by the two-dimensional representation of the SL structures were sufficient to obtain significant results, and better results were not achieved by using descriptors derived from three-dimensional representations of SLs. Such models based on physico-chemical properties can project new design SLs, similar structures from literature or even unreported structures in two-dimensional chemical space. Therefore, the generated SOMs can predict the most probable tribe where a biologically active molecule can be found according Bremer classification.

  11. Establishment of an in silico phospholipidosis prediction method using descriptors related to molecular interactions causing phospholipid-compound complex formation.

    Science.gov (United States)

    Haranosono, Yu; Nemoto, Shingo; Kurata, Masaaki; Sakaki, Hideyuki

    2016-04-01

    Although phospholipidosis (PLD) often affects drug development, there is no convenient in vitro or in vivo test system for PLD detection. In this study, we developed an in silico PLD prediction method based on the PLD-inducing mechanism. We focused on phospholipid (PL)-compound complex formation, which inhibits PL degradation by phospholipase. Thus, we used some molecular interactions, such as electrostatic interactions, hydrophobic interactions, and intermolecular forces, between PL and compounds as descriptors. First, we performed descriptor screening for intermolecular force and then developed a new in silico PLD prediction using descriptors related to molecular interactions. Based on the screening, we identified molecular refraction (MR) as a descriptor of intermolecular force. It is known that ClogP and most-basic pKa can be used for PLD prediction. Thereby, we developed an in silico prediction method using ClogP, most-basic pKa, and MR, which were related to hydrophobic interactions, electrostatic interactions, and intermolecular forces. In addition, a resampling method was used to determine the cut-off values for each descriptor. We obtained good results for 77 compounds as follows: sensitivity = 95.8%, specificity = 75.9%, and concordance = 88.3%. Although there is a concern regarding false-negative compounds for pKa calculations, this predictive ability will be adequate for PLD screening. In conclusion, the mechanism-based in silico PLD prediction method provided good prediction ability, and this method will be useful for evaluating the potential of drugs to cause PLD, particularly in the early stage of drug development, because this method only requires knowledge of the chemical structure.

  12. EDGE COVERING COLORING AND FRACTIONAL EDGE COVERING COLORING

    Institute of Scientific and Technical Information of China (English)

    MIAOLianying; LIUGuizhen

    2002-01-01

    Let G be a graph with edge set E(G).S E(G)is called an edge cover of G if every vertex of G is an end vertex of some edges in S.The edge covering chromatic number of a graph G,denoted by Xc(G),is the maximum size of a partition of E(G) into edge covers of G.It is known that for any graph G with minimum degree δ,δ-1≤Xc(G)≤δ.The fractional edge covering chromatic number of a graph G,denoted by Xcf(G),is the fractional matiching number of the edge covering hypergraph H of G whose vertices are the edges of G and whose hypereges the edge covers of G.In this paper,we study the relation between Xc(G) and δfor any graph G,and give a new simple proof of the inequalities δ-1≤Xc(G)≤δ by the technique of graph coloring.For any graph G,we give an exact formula o Xcf(G),that is,Xcf(G)=min{δ,λ(G)},where λ(G)=minCS/S/2 and the minimum is taken over all noempty subsets S of V(G) and C[S] is the set of edges that have at least one end in S.δ

  13. EDGE COVERING COLORING AND FRACTIONAL EDGE COVERING COLORING

    Institute of Scientific and Technical Information of China (English)

    MIAO Lianying; LIU Guizhen

    2002-01-01

    Let G be a graph with edge set E(G). S _C E(G) is called an edge cover of G if every vertex of G is an end vertex of some edges in S. The edge covering chromatic number of a graph G, denoted by X'c(G) , is the maximum size of a partition of E(G) into edge covers of G. It is known that for any graph G with minimum degree δ, δ - 1 ≤ X'c(G) ≤ δ.The fractional edge covering chromatic number of a graph G, denoted by X'cf(G), is the fractional matching number of the edge covering hypergraph H of G whose vertices are the edges of G and whose hyperedges the edge covers of G. In this paper, we study the relation between X'c(G) and δ for any graph G, and give a new simple proof of the inequalities δ - 1 ≤ X'c(G) ≤ δ by the technique of graph coloring. For any graph G, we give an exact formula of X'cf(G), that is, X'cf(G)=min{δ,λ(G)}, where λ(G)=min |C[S]|/[|S|/2]and the minimum is taken over all noempty subsets S of V(G) and C[S] is the set of edges that have at least one end in S.

  14. Determining Covers in Combinational Circuits

    Directory of Open Access Journals (Sweden)

    Ljubomir Cvetkovic

    2011-05-01

    Full Text Available In this paper we propose a procedure for determining 0- or 1-cover of an arbitrary line in a combinational circuit. When determining a cover we do not need Boolean expression for the line; only the circuit structure is used. Within the proposed procedure we use the tools of the cube theory, in particular, some operations defined on cubes. The procedure can be applied for determining 0- and 1- covers of output lines in programmable logic devices. Basically, this procedure is a method for the analysis of a combinational circuit.

  15. Modelling of retention of pesticides in reversed-phase high-performance liquid chromatography: Quantitative structure-retention relationships based on solute quantum-chemical descriptors and experimental (solvatochromic and spin-probe) mobile phase descriptors

    Energy Technology Data Exchange (ETDEWEB)

    D' Archivio, Angelo Antonio [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi di L' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy)]. E-mail: darchivi@univaq.it; Ruggieri, Fabrizio [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi di L' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy); Mazzeo, Pietro [Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita degli Studi di L' Aquila, Via Vetoio, 67010 Coppito, L' Aquila (Italy); Tettamanti, Enzo [Dipartimento di Scienze Biomediche Comparate, Universita di Teramo, P.zzale A. Moro 45, 64100 Teramo (Italy)

    2007-06-19

    A quantitative structure-retention relationship (QSRR) analysis based on multilinear regression (MLR) and artificial neural networks (ANNs) is carried out to model the combined effect of solute structure and eluent composition on the retention behaviour of pesticides in isocratic reversed-phase high-performance liquid chromatography (RP-HPLC). The octanol-water partition coefficient and four quantum chemical descriptors (the total dipole moment, the mean polarizability, the anisotropy of the polarizability and a descriptor of hydrogen-bonding based on the atomic charges on acidic and basic chemical functionalities) are considered as solute descriptors. In order to identify suitable mobile phase descriptors, encoding composition-dependent properties of both methanol- and acetonitrile-containing mobile phases, the Kamlet-Taft solvatochromic parameters (polarity-dipolarity, hydrogen-bond acidity and hydrogen-bond basicity, {pi} {sup *}, {alpha} and {beta}, respectively) and the {sup 14}N hyperfine-splitting constant (a {sub N}) of a spin-probe dissolved in the eluent are examined. A satisfactory description of mobile phase properties influencing the solute retention is provided by a {sub N} and {beta} or alternatively {pi} {sup *} and {beta}. The two seven-parameter models resulting from combination of a {sub N} and {beta}, or {pi} {sup *} and {beta}, with the solute descriptors were tested on a set of 26 pesticides representative of 10 different chemical classes in a wide range of mobile phase composition (30-60% (v/v) water-methanol and 30-70% (v/v) water-acetonitrile). Within the explored experimental range, the acidity of the eluent, as quantified by {alpha}, is almost constant, and this parameter is in fact irrelevant. The results reveal that a {sub N} and {pi} {sup *}, that can be considered as interchangeable mobile phase descriptors, are the most influent variables in the respective models. The predictive ability of the proposed models, as tested on an

  16. COVER

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    The outcome of hepatic B virus(HBV)infection is the result of complex interactions between replicating HBV and the innate/adaptive immune system.As an important lectin complement pathway activator,human ficolin-2 is secreted from liver cells and contributes to the clearance of viral infections and lysis of enveloped virions,which has been implicated as an anti-infection innate immune molecule.In this issue,a research group lead by Drs.XiaoLian Zhang and Fengling Luo,investigated the serum and liver tissue ficolin-2

  17. COVER

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    <正>This issue of Virologica Sinica is to celebrate the 100th anniversary of the discovery of "filterable lytic factor" or "bacteriophage"(1915-2015).During the past 100 years,both basic knowledge and applications of bacteriophages have been substantially explored and developed.In recent years,bacteriophage research is booming and holding the hope

  18. Cover

    OpenAIRE

    Frontiers of Biogeography, Editorial Office

    2017-01-01

    Frontiers of Biogeography new logo. This logo feeds on the theme created for the new IBS corporate image, and represents four overlapping hypervolumes in the form of a butterfly’s wings, flying over four niche response curves in the form of hills, mountains and the sea (see Dawson et al. in this issue for details).

  19. Cover

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Soybean growth habit is an important agronomic trait,and related genes have been cloned recently,while the variation of the major gene and how this gene was selected during the soybean breeding in China remain unknown.In the diverse soybean germplasm,it is hard to distinguish the determinate from the semi‐determinate phenotype.The development of functional Indel and CAPS markers from the Gm Tfl1 gene of the Dt1 locus makes it possible to evaluate genotype of the germplasm.The different allele

  20. COVER

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Hepatitis B virus(HBV)infection remains a major global health problem because current therapies rarely eliminate the replicative template of HBV,which is the covalently closed circular DNA(ccc DNA).As an accurate and efficient genome editing tool,clustered regularly interspaced palindromic repeat(CRISPR)-associated(Cas)9 system represents a very promising potential

  1. GAP Land Cover - Tiled Raster

    Data.gov (United States)

    Minnesota Department of Natural Resources — This raster dataset is a detailed (1-acre minimum), hierarchically organized vegetation cover map produced by computer classification of combined two-season pairs of...

  2. Forest Cover Types - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer portrays general forest cover types for the United States. Data were derived from Advanced Very High Resolution Radiometer (AVHRR) composite images...

  3. Land-cover change detection

    Science.gov (United States)

    Chen, Xuexia; Giri, Chandra; Vogelmann, James

    2012-01-01

    Land cover is the biophysical material on the surface of the earth. Land-cover types include grass, shrubs, trees, barren, water, and man-made features. Land cover changes continuously.  The rate of change can be either dramatic and abrupt, such as the changes caused by logging, hurricanes and fire, or subtle and gradual, such as regeneration of forests and damage caused by insects (Verbesselt et al., 2001).  Previous studies have shown that land cover has changed dramatically during the past sevearal centuries and that these changes have severely affected our ecosystems (Foody, 2010; Lambin et al., 2001). Lambin and Strahlers (1994b) summarized five types of cause for land-cover changes: (1) long-term natural changes in climate conditions, (2) geomorphological and ecological processes, (3) human-induced alterations of vegetation cover and landscapes, (4) interannual climate variability, and (5) human-induced greenhouse effect.  Tools and techniques are needed to detect, describe, and predict these changes to facilitate sustainable management of natural resources.

  4. Good covers are algorithmically unrecognizable

    CERN Document Server

    Tancer, Martin

    2012-01-01

    A good cover in R^d is a collection of open contractible sets in R^d such that the intersection of any subcollection is either contractible or empty. Motivated by an analogy with convex sets, intersection patterns of good covers were studied intensively. Our main result is that intersection patterns of good covers are algorithmically unrecognizable. More precisely, the intersection pattern of a good cover can be stored in a simplicial complex called nerve which records which subfamilies of the good cover intersect. A simplicial complex is topologically d-representable if it is isomorphic to the nerve of a good cover in R^d. We prove that it is algorithmically undecidable whether a given simplicial complex is topologically d-representable for any fixed d \\geq 5. As an auxiliary result we prove that if a simplicial complex is PL embeddable into R^d, then it is topologically d-representable. We also supply this result with showing that if a "sufficiently fine" subdivision of a k-dimensional complex is d-represen...

  5. Mechanistic Details and Reactivity Descriptors in Oxidation and Acid Catalysis of Methanol

    Energy Technology Data Exchange (ETDEWEB)

    Deshlahra, Prashant; Carr, Robert T.; Chai, Song-Hai; Iglesia, Enrique

    2015-02-06

    Acid and redox reaction rates of CH₃OH-O₂ mixtures on polyoxometalate (POM) clusters, together with isotopic, spectroscopic, and theoretical assessments of catalyst properties and reaction pathways, were used to define rigorous descriptors of reactivity and to probe the compositional effects for oxidative dehydrogenation (ODH) and dehydration reactions. ³¹P-MAS NMR, transmission electron microscopy and titrations of protons with di-tert-butylpyridine during catalysis showed that POM clusters retained their Keggin structure upon dispersion on SiO₂ and after use in CH₃OH reactions. The effects of CH₃OH and O₂ pressures and of D-substitution on ODH rates show that C-H activation in molecularly adsorbed CH₃OH is the sole kinetically relevant step and leads to reduced centers as intermediates present at low coverages; their concentrations, measured from UV-vis spectra obtained during catalysis, are consistent with the effects of CH₃OH/O₂ ratios predicted from the elementary steps proposed. First-order ODH rate constants depend strongly on the addenda atoms (Mo vs W) but weakly on the central atom (P vs Si) in POM clusters, because C-H activation steps inject electrons into the lowest unoccupied molecular orbitals (LUMO) of the clusters, which are the d-orbitals at Mo⁶⁺ and W⁶⁺ centers. H-atom addition energies (HAE) at O-atoms in POM clusters represent the relevant theoretical probe of the LUMO energies and of ODH reactivity. The calculated energies of ODH transition states at each O-atom depend linearly on their HAE values with slopes near unity, as predicted for late transition states in which electron transfer and C-H cleavage are essentially complete. HAE values averaged over all accessible O-atoms in POM clusters provide the appropriate reactivity descriptor for oxides whose known structures allow accurate HAE calculations. CH₃OH dehydration proceeds via parallel pathways mediated by late carbenium-ion transition states; effects of

  6. Determination of descriptors for polycyclic aromatic hydrocarbons and related compounds by chromatographic methods and liquid-liquid partition in totally organic biphasic systems.

    Science.gov (United States)

    Ariyasena, Thiloka C; Poole, Colin F

    2014-09-26

    Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions containing acetonitrile, methanol and tetrahydrofuran as strength adjusting solvents are combined with liquid-liquid partition coefficients in totally organic biphasic systems to calculate descriptors for 23 polycyclic aromatic hydrocarbons and eighteen related compounds of environmental interest. The use of a consistent protocol for the above measurements provides descriptors that are more self consistent for the estimation of physicochemical properties (octanol-water, air-octanol, air-water, aqueous solubility, and subcooled liquid vapor pressure). The descriptor in this report tend to have smaller values for the L and E descriptors and random differences in the B and S descriptors compared with literature sources. A simple atom fragment constant model is proposed for the estimation of descriptors from structure for polycyclic aromatic hydrocarbons. The new descriptors show no bias in the prediction of the air-water partition coefficient for polycyclic aromatic hydrocarbons unlike the literature values.

  7. Application of breast MRI for prediction of lymph node metastases - systematic approach using 17 individual descriptors and a dedicated decision tree

    Energy Technology Data Exchange (ETDEWEB)

    Dietzel, Matthias; Baltzer, Pascal A.T.; Groeschel, Tobias; Kaiser, Werner A. (Inst. of Diagnostic and Interventional Radiology, Friedrich-Schiller-Univ. Jena (Germany)), e-mail: matthias.dietzel@med.uni-jena.de; Vag, Tibor (Dept. of Radiology, Klinikum rechts der Isar der Technischen Universitaet, Munich (Germany)); Gajda, Mieczyslaw (Inst. of Pathology, Friedrich-Schiller-Univ., Jena (Germany)); Camara, Oumar (Clinic of Gynecology, Friedrich-Schiller-Univ., Jena (Germany))

    2010-10-15

    Background: The presence of lymph node metastases (LNMs) is one of the most important prognostic factors in breast cancer. Purpose: To correlate a detailed catalog of 17 descriptors in breast MRI (bMRI) with the presence of LNMs and to identify useful combinations of such descriptors for the prediction of LNMs using a dedicated decision tree. Material and Methods: A standardized protocol and study design was applied in this IRB-approved study (T1-weighted FLASH; 0.1 mmol/kg body weight Gd-DTPA; T2-weighted TSE; histological verification after bMRI). Two experienced radiologists performed prospective evaluation of the previously acquired examination in consensus. In every lesion 17 previously published descriptors were assessed. Subgroups of primary breast cancers with (N+: 97) and without LNM were created (N-: 253). The prevalence and diagnostic accuracy of each descriptor were correlated with the presence of LNM (chi-square test; diagnostic odds ratio/DOR). To identify useful combinations of descriptors for the prediction of LNM a chi-squared automatic interaction detection (CHAID) decision tree was applied. Results: Seven of 17 descriptors were significantly associated with LNMs. The most accurate were 'Skin thickening' (P < 0.001; DOR 5.9) and 'Internal enhancement' (P < 0.001; DOR =13.7). The CHAID decision tree identified useful combinations of descriptors: 'Skin thickening' plus 'Destruction of nipple line' raised the probability of N+ by 40% (P< 0.05). In case of absence of 'Skin thickening', 'Edema', and 'Irregular margins', the likelihood of N+ was 0% (P<0.05). Conclusion: Our data demonstrate the close association of selected breast MRI descriptors with nodal status. If present, such descriptors can be used - as stand alone or in combination - to accurately predict LNM and to stratify the patient's prognosis

  8. Sensory descriptors of cocoa beans from cultivated trees of Soconusco, Chiapas, Mexico

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    Alfredo Vázquez-Ovando

    2015-06-01

    Full Text Available The odor and taste profile of cocoa bean samples obtained from trees cultivated in southern Mexico were evaluated by trained panelists. Seven representative samples (groups of a total of 45 were analyzed. Four attributes of taste (sweetness, bitterness, acidity and astringency, and nine of odor (chocolate, nutty, hazelnut, sweet, acidity, roasted, spicy, musty and off-odor were evaluated. A sample (G7 with higher scores in sweet taste and sweet and nutty odors was detected, as well as a high association between these descriptors and the sample, analyzed through principal component analysis (PCA. Similarly, samples that showed high scores for non-desired odors in cocoas such as off-odor and musty were identified and related by PCA to roasted odor and astringent taste (G2 and G4. Based on this scores, the samples were listed in descending order by their sensory quality as G7> G5> G6> G3> G1> G4> G2.

  9. Results from the Use of Molecular Descriptors Family on Structure Property/Activity Relationships

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    Sorana-Daniela Bolboacă

    2007-03-01

    Full Text Available The aim of the paper is to present the results obtained by utilization of an originalapproach called Molecular Descriptors Family on Structure-Property (MDF-SPR andStructure-Activity Relationships (MDF-SAR applied on classes of chemical compoundsand its usefulness as precursors of models elaboration of new compounds with betterproperties and/or activities and low production costs. The MDF-SPR/MDF-SARmethodology integrates the complex information obtained from compound’s structure inunitary efficient models in order to explain properties/activities. The methodology has beenapplied on a number of thirty sets of chemical compounds. The best subsets of moleculardescriptors family members able to estimate and predict property/activity of interest wereidentified and were statistically and visually analyzed. The MDF-SPR/MDF-SAR modelswere validated through internal and/or external validation methods. The estimation andprediction abilities of the MDF-SPR/MDF-SAR models were compared with previousreported models by applying of correlated correlation analysis, which revealed that theMDF-SPR/MDF-SAR methodology is reliable. The MDF-SPR/MDF-SAR methodologyopens a new pathway in understanding the relationships between compound’s structure andproperty/activity, in property/activity prediction, and in discovery, investigation andcharacterization of new chemical compounds, more competitive as costs andproperty/activity, being a method less expensive comparative with experimental methods.

  10. Molecular-orbital and structural descriptors in theoretical investigation of electroreduction of nitrodiazoles

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    BRANKO KOLARIC

    2005-07-01

    Full Text Available It is shown how a simple theoretical approach can be used for the investigation of electro-organic reactions.Mononitroimidazoles and mononitropyrazoles were studied by the semiempirical MNDO-PM3 molecular orbital method. The electrochemical reduction potentials of diazoles have been correlated with the energy of the lowest unoccupied molecular orbital (LUMO. It was found that an admirable correlation could be obtained by the introduction of simple structural descriptors as a correction to the energy of the LUMO. The interaction of a molecule with its surrounding depends on electrostatic potential and on steric hindrance. Most of these steric effects are taken into account using two parameters having a very limited set of integer values. The first (b is the position of a ring substituent regarding ring nitrogens, which accounts for the different orientations of dipole moments and for the different shape of the electrostatic potential. The second (structural parameter (t is the type of the ring, which accounts mostly for different modes of electrode approach, and for different charge polarization patterns in two diazole rings. The extended correlation with ELUMO, b and t, is very good, having a regression coefficient r = 0.991. The intrinsic importance of b and t is exemplified by their high statistical weight.

  11. APPLICATION OF BINARY DESCRIPTORS TO MULTIPLE FACE TRACKING IN VIDEO SURVEILLANCE SYSTEMS

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    A. L. Oleinik

    2016-07-01

    Full Text Available Subject of Research. The paper deals with the problem of multiple face tracking in a video stream. The primary application of the implemented tracking system is the automatic video surveillance. The particular operating conditions of surveillance cameras are taken into account in order to increase the efficiency of the system in comparison to existing general-purpose analogs. Method. The developed system is comprised of two subsystems: detector and tracker. The tracking subsystem does not depend on the detector, and thus various face detection methods can be used. Furthermore, only a small portion of frames is processed by the detector in this structure, substantially improving the operation rate. The tracking algorithm is based on BRIEF binary descriptors that are computed very efficiently on modern processor architectures. Main Results. The system is implemented in C++ and the experiments on the processing rate and quality evaluation are carried out. MOTA and MOTP metrics are used for tracking quality measurement. The experiments demonstrated the four-fold processing rate gain in comparison to the baseline implementation that processes every video frame with the detector. The tracking quality is on the adequate level when compared to the baseline. Practical Relevance. The developed system can be used with various face detectors (including slow ones to create a fully functional high-speed multiple face tracking solution. The algorithm is easy to implement and optimize, so it may be applied not only in full-scale video surveillance systems, but also in embedded solutions integrated directly into cameras.

  12. Environmental quality of Italian marine water by means of marine strategy framework directive (MSFD descriptor 9.

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    Chiara Maggi

    Full Text Available ISPRA, on behalf of the Italian Ministry of Environment, carried out the initial assessment of environmental quality status of the 3 Italian subregions (Mediterranean Sea Region on Descriptor 9. The approach adopted to define the GES started to verify that contaminants in fish and other seafood for human consumption did not exceed levels established by Community legislation (Reg. 1881/2006 and further updates. As the Marine Strategy Framework Directive (MSFD requires to use health tools to assess the environment, Italy decided to adopt a statistical range of acceptance of thresholds identified by national (D.Lgs. 152/2006 concerning water quality required for mussel farms and international legislation (Reg. 1881/2006 and further updates, which allowed to use the health results and to employ them for the assessment of environmental quality. Italy proposed that Good Environmental Status (GES is achieved when concentrations are lower than statistical range of acceptance, estimated on samples of fish and fishery products coming from only national waters. GIS-based approach a to perform different integration levels for station, cell's grid and years, was used; the elaborations allowed to judge the environmental quality good.

  13. Comprehensive approach for predicting toxicological effects of ionic liquids on several biological systems using unified descriptors

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    Cho, Chul-Woong; Stolte, Stefan; Yun, Yeoung-Sang

    2016-09-01

    The challenge and opportunity for design of environmentally-benign ionic liquids (ILs) would start from prediction of their toxicological effects on several endpoints solely based on the structural formulas. Especially, a comprehensive yet simple equation able to predict several biological responses to IL toxicity is of much advantage. Therefore, based on 50 toxicity testing systems on ILs a comprehensively approachable prediction method was developed. For the modelling, approximately 1600 toxicity values measured by several biological systems and an amended linear free energy relationship (LFER) model were used. Since the toxicological activities of an IL could be differently described according to sensitivity of toxicity testing systems, the sensitivity of each of toxicity testing systems was also estimated in the modelling. By statistical analysis with the calculated descriptors, a LFER model was built. Also the sensitivity value of each system on the basis of the comprehensively approachable model was numerically estimated. In results, it was observed that the combination of single model and sensitivity terms was able to predict each of 50 toxicological effects of ILs with R2 of 0.593~0.978, and SE of 0.098~0.699 log unit, and the total data set with R2 of 0.901 and SE of 0.426 log unit.

  14. Exploring spatial patterns of vulnerability for diverse biodiversity descriptors in regional conservation planning.

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    Vimal, Ruppert; Pluvinet, Pascal; Sacca, Céline; Mazagol, Pierre-Olivier; Etlicher, Bernard; Thompson, John D

    2012-03-01

    In this study, we developed a multi-criteria assessment of spatial variability of the vulnerability of three different biodiversity descriptors: sites of high conservation interest by virtue of the presence of rare or remarkable species, extensive areas of high ecological integrity, and landscape diversity in grid cells across an entire region. We assessed vulnerability in relation to (a) direct threats in and around sites to a distance of 2 km associated with intensive agriculture, building and road infrastructure and (b) indirect effects of human population density on a wider scale (50 km). The different combinations of biodiversity and threat indicators allowed us to set differential priorities for biodiversity conservation and assess their spatial variation. For example, with this method we identified sites and grid cells which combined high biodiversity with either high threat values or low threat values for the three different biodiversity indicators. In these two classes the priorities for conservation planning will be different, reduce threat values in the former and restrain any increase in the latter. We also identified low priority sites (low biodiversity with either high or low threats). This procedure thus allows for the integration of a spatial ranking of vulnerability into priority setting for regional conservation planning.

  15. Detection of Interactions between Proteins through Rotation Forest and Local Phase Quantization Descriptors

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    Leon Wong

    2015-12-01

    Full Text Available Protein-Protein Interactions (PPIs play a vital role in most cellular processes. Although many efforts have been devoted to detecting protein interactions by high-throughput experiments, these methods are obviously expensive and tedious. Targeting these inevitable disadvantages, this study develops a novel computational method to predict PPIs using information on protein sequences, which is highly efficient and accurate. The improvement mainly comes from the use of the Rotation Forest (RF classifier and the Local Phase Quantization (LPQ descriptor from the Physicochemical Property Response (PR Matrix of protein amino acids. When performed on three PPI datasets including Saccharomyces cerevisiae, Homo sapiens, and Helicobacter pylori, we obtained good results of average accuracies of 93.8%, 97.96%, and 89.47%, which are much better than in previous studies. Extensive validations have also been explored to evaluate the performance of the Rotation Forest ensemble classifier with the state-of-the-art Support Vector Machine classifier. These promising results indicate that the proposed method might play a complementary role for future proteomics research.

  16. Comparison of efficiency of distance measurement methodologies in mango (Mangifera indica) progenies based on physicochemical descriptors.

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    Alves, E O S; Cerqueira-Silva, C B M; Souza, A M; Santos, C A F; Lima Neto, F P; Corrêa, R X

    2012-03-14

    We investigated seven distance measures in a set of observations of physicochemical variables of mango (Mangifera indica) submitted to multivariate analyses (distance, projection and grouping). To estimate the distance measurements, five mango progeny (total of 25 genotypes) were analyzed, using six fruit physicochemical descriptors (fruit weight, equatorial diameter, longitudinal diameter, total soluble solids in °Brix, total titratable acidity, and pH). The distance measurements were compared by the Spearman correlation test, projection in two-dimensional space and grouping efficiency. The Spearman correlation coefficients between the seven distance measurements were, except for the Mahalanobis' generalized distance (0.41 ≤ rs ≤ 0.63), high and significant (rs ≥ 0.91; P < 0.001). Regardless of the origin of the distance matrix, the unweighted pair group method with arithmetic mean grouping method proved to be the most adequate. The various distance measurements and grouping methods gave different values for distortion (-116.5 ≤ D ≤ 74.5), cophenetic correlation (0.26 ≤ rc ≤ 0.76) and stress (-1.9 ≤ S ≤ 58.9). Choice of distance measurement and analysis methods influence the.

  17. Fusion of Visible and Thermal Descriptors Using Genetic Algorithms for Face Recognition Systems

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    Gabriel Hermosilla

    2015-07-01

    Full Text Available The aim of this article is to present a new face recognition system based on the fusion of visible and thermal features obtained from the most current local matching descriptors by maximizing face recognition rates through the use of genetic algorithms. The article considers a comparison of the performance of the proposed fusion methodology against five current face recognition methods and classic fusion techniques used commonly in the literature. These were selected by considering their performance in face recognition. The five local matching methods and the proposed fusion methodology are evaluated using the standard visible/thermal database, the Equinox database, along with a new database, the PUCV-VTF, designed for visible-thermal studies in face recognition and described for the first time in this work. The latter is created considering visible and thermal image sensors with different real-world conditions, such as variations in illumination, facial expression, pose, occlusion, etc. The main conclusions of this article are that two variants of the proposed fusion methodology surpass current face recognition methods and the classic fusion techniques reported in the literature, attaining recognition rates of over 97% and 99% for the Equinox and PUCV-VTF databases, respectively. The fusion methodology is very robust to illumination and expression changes, as it combines thermal and visible information efficiently by using genetic algorithms, thus allowing it to choose optimal face areas where one spectrum is more representative than the other.

  18. Towards a Holistic Cortical Thickness Descriptor: Heat Kernel-Based Grey Matter Morphology Signatures.

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    Wang, Gang; Wang, Yalin

    2017-02-15

    In this paper, we propose a heat kernel based regional shape descriptor that may be capable of better exploiting volumetric morphological information than other available methods, thereby improving statistical power on brain magnetic resonance imaging (MRI) analysis. The mechanism of our analysis is driven by the graph spectrum and the heat kernel theory, to capture the volumetric geometry information in the constructed tetrahedral meshes. In order to capture profound brain grey matter shape changes, we first use the volumetric Laplace-Beltrami operator to determine the point pair correspondence between white-grey matter and CSF-grey matter boundary surfaces by computing the streamlines in a tetrahedral mesh. Secondly, we propose multi-scale grey matter morphology signatures to describe the transition probability by random walk between the point pairs, which reflects the inherent geometric characteristics. Thirdly, a point distribution model is applied to reduce the dimensionality of the grey matter morphology signatures and generate the internal structure features. With the sparse linear discriminant analysis, we select a concise morphology feature set with improved classification accuracies. In our experiments, the proposed work outperformed the cortical thickness features computed by FreeSurfer software in the classification of Alzheimer's disease and its prodromal stage, i.e., mild cognitive impairment, on publicly available data from the Alzheimer's Disease Neuroimaging Initiative. The multi-scale and physics based volumetric structure feature may bring stronger statistical power than some traditional methods for MRI-based grey matter morphology analysis.

  19. Spiking Cortical Model Based Multimodal Medical Image Fusion by Combining Entropy Information with Weber Local Descriptor.

    Science.gov (United States)

    Zhang, Xuming; Ren, Jinxia; Huang, Zhiwen; Zhu, Fei

    2016-09-15

    Multimodal medical image fusion (MIF) plays an important role in clinical diagnosis and therapy. Existing MIF methods tend to introduce artifacts, lead to loss of image details or produce low-contrast fused images. To address these problems, a novel spiking cortical model (SCM) based MIF method has been proposed in this paper. The proposed method can generate high-quality fused images using the weighting fusion strategy based on the firing times of the SCM. In the weighting fusion scheme, the weight is determined by combining the entropy information of pulse outputs of the SCM with the Weber local descriptor operating on the firing mapping images produced from the pulse outputs. The extensive experiments on multimodal medical images show that compared with the numerous state-of-the-art MIF methods, the proposed method can preserve image details very well and avoid the introduction of artifacts effectively, and thus it significantly improves the quality of fused images in terms of human vision and objective evaluation criteria such as mutual information, edge preservation index, structural similarity based metric, fusion quality index, fusion similarity metric and standard deviation.

  20. Spiking Cortical Model Based Multimodal Medical Image Fusion by Combining Entropy Information with Weber Local Descriptor

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    Xuming Zhang

    2016-09-01

    Full Text Available Multimodal medical image fusion (MIF plays an important role in clinical diagnosis and therapy. Existing MIF methods tend to introduce artifacts, lead to loss of image details or produce low-contrast fused images. To address these problems, a novel spiking cortical model (SCM based MIF method has been proposed in this paper. The proposed method can generate high-quality fused images using the weighting fusion strategy based on the firing times of the SCM. In the weighting fusion scheme, the weight is determined by combining the entropy information of pulse outputs of the SCM with the Weber local descriptor operating on the firing mapping images produced from the pulse outputs. The extensive experiments on multimodal medical images show that compared with the numerous state-of-the-art MIF methods, the proposed method can preserve image details very well and avoid the introduction of artifacts effectively, and thus it significantly improves the quality of fused images in terms of human vision and objective evaluation criteria such as mutual information, edge preservation index, structural similarity based metric, fusion quality index, fusion similarity metric and standard deviation.