WorldWideScience

Sample records for twentieth-century population genetical

  1. Mammalian developmental genetics in the twentieth century.

    Science.gov (United States)

    Artzt, Karen

    2012-12-01

    This Perspectives is a review of the breathtaking history of mammalian genetics in the past century and, in particular, of the ways in which genetic thinking has illuminated aspects of mouse development. To illustrate the power of that thinking, selected hypothesis-driven experiments and technical advances are discussed. Also included in this account are the beginnings of mouse genetics at the Bussey Institute, Columbia University, and The Jackson Laboratory and a retrospective discussion of one of the classic problems in developmental genetics, the T/t complex and its genetic enigmas.

  2. [Constant or break? On the relations between human genetics and eugenics in the Twentieth Century].

    Science.gov (United States)

    Germann, Pascal

    2015-07-01

    The history of human genetics has been a neglected topic in history of science and medicine for a long time. Only recently, have medical historians begun to pay more attention to the history of human heredity. An important research question deals with the interconnections between human genetics and eugenics. This paper addresses this question: By focusing on a Swiss case study, the investigation of the heredity of goiter, I will argue that there existed close but also ambiguous relations between heredity research and eugenics in the twentieth century. Studies on human heredity often produced evidence that challenged eugenic aims and ideas. Concurrently, however, these studies fostered visions of genetic improvement of human populations.

  3. Hungarian Population Discourses in the Twentieth Century: The Problem of Declining Birth Rates

    Directory of Open Access Journals (Sweden)

    Ildikó Szántó

    2016-01-01

    Full Text Available Falling birth rates had already been recorded as early as the late-eighteenth century in south-western Hungary in the Ormánság. Population loss from low birth rate remained one of the main topics writers and sociologists focused on in the twentieth century. The issue of Hungarian population decline was highlighted among the social ills in the interwar period, which was one of several subjects that divided intellectuals into ‘populists’ and ‘urbanites’. Following the impact of the low birth rate figures in the 1960s, the populists’ views of the 1930s resurfaced in public discourse in the 1960s and 1970s and up to the present day. The concern about the increasing trend of single-child families in rural settlements as well as in urban areas appeared in the various works of Hungarian writers and journalists throughout the previous century. The present paper intends to focus on the intellectual background to the public debates on the population issue, outlining the accounts of the interwar ‘village explorers’ briefly, and the way they are related to the pre-Second World War populist movement. Finally the reappearance of the debates between populists and non-populists of the 1970s is discussed, a debate that is still continuing.

  4. Twentieth Century Moral Philosophy

    OpenAIRE

    Stout, Rowland

    2008-01-01

    Despite being somewhat long in the tooth at the time, Aristotle, Hume and Kant were still dominating twentieth century moral philosophy. Much of the progress made in that century came from a detailed working through of each of their approaches by the expanding and increasingly professionalized corps of academic philosophers. And this progress can be measured not just by the quality and sophistication of moral philosophy at the end of that century, but also by the narrowing of s...

  5. St. Augustine in Twentieth-Century Music

    DEFF Research Database (Denmark)

    Petersen, Nils Holger

    2012-01-01

    A discussion - in a cultural historical perspective - of primarily two important twentieth-century musical works setting texts by St Augustine: Klaus Huber's Soliloquia Sancti Aurelii Augustini and Michael Tippett's The Vision of Saint Augustine.......A discussion - in a cultural historical perspective - of primarily two important twentieth-century musical works setting texts by St Augustine: Klaus Huber's Soliloquia Sancti Aurelii Augustini and Michael Tippett's The Vision of Saint Augustine....

  6. Symptom removal: the twentieth century experience.

    Science.gov (United States)

    Weitzenhoffer, André M

    2004-01-01

    The twentieth century hypnosis literature regarding the use of direct symptom removal with hypnosis is in strong contrast with that of the nineteenth. It shows much ambivalence about the use of symptom removal. Objections, largely based on conclusions drawn from psychoanalytic theory, led many twentieth century psychotherapists to reject direct symptom removal. However, a certain amount of empirical evidence, scattered through the literature, has accumulated during the twentieth century to support this rejection. The lack of satisfactory twentieth century statistics and of nineteenth century details concerning hypnotic interventions that were used, makes it impossible to satisfactorily account for the discrepancy in experiences of the nineteenth and twentieth centuries. Although therapists did not altogether abandon working directly with symptoms, many opted instead for modifying and manipulating them by suggestion instead of completely removing them, usually allowing the patient to retain a psychodynamically suitable substitute. Here again a lack of adequate statistics prevents one from being able to properly appraise the effectiveness of this approach which has remained the preferred one for a number of therapists.

  7. Black Women Workers in the Twentieth Century.

    Science.gov (United States)

    Newman, Debra Lynn

    1986-01-01

    At the beginning of the twentieth century one-third of black women worked; most did agricultural or domestic work. Gradually as employment benefits increased and anti-discrimination laws were enforced, work opportunities for black women became more varied and better paying. (VM)

  8. Twentieth-Century Art: Issues of Representation.

    Science.gov (United States)

    Springer, Julie

    1990-01-01

    Presents lesson plans designed for secondary students that assess the role of naturalistic representation in twentieth-century art by examining the artwork of four artists: Pablo Picasso, Rene Magritte, David Smith, and Jackson Pollock. Provides background information on each illustration, and outlines discussion and art production activities for…

  9. Rediscovery of Early Twentieth-Century Ecotheology

    OpenAIRE

    Pihkala Panu

    2016-01-01

    In this article, I examine the early history of Christian environmentalism (“ecotheology”) in the twentieth century. I delineate four strands of early ecotheology: agrarian ecotheology; social Christianity; British contributions; and “post-liberal” foundations for later ecotheological movements. I show that ecotheology was a slowly-rising movement, which had notable proponents. I argue that these early ecotheologians are significant for several reasons. First, these writings support the view ...

  10. [Twentieth-century Penelopes: popular culture revisited].

    Science.gov (United States)

    Favaro, Cleci Eulalia

    2010-01-01

    During their settlement of the so-called Old Italian Colonies of Rio Grande do Sul, immigrants constructed a set of positive values that were to serve as an emotional support and a means of outside communication. When women immigrants embroidered images and sayings on wall hangings or kitchen towels made of rustic fabric, they helped nourish the dream of a better life, sought by all and achieved by some. The objects crafted by these twentieth-century Penelopes bear witness to a way of doing, thinking, and acting. Local museums and exhibits have fostered the recovery of old-time embroidery techniques and themes; sold at open-air markets and regional festivals, these products represent income for women whose age excludes them from the formal labor market.

  11. Unmarried motherhood in twentieth-century England.

    Science.gov (United States)

    Thane, Pat

    2011-01-01

    This article explores the experiences of unmarried mothers who kept and tried to raise their children between World War One and the end of the twentieth century. It argues that there has not been a simple progression from their experiencing social stigma and ostracism to more enlightened attitudes since the 1970s. Rather there is a great deal that has hitherto been unknown about what the evidence suggests were very diverse experiences and attitudes throughout the period. A major change since the 1970s has been from pervasive secrecy about unmarried motherhood, cohabitation, adultery and similar 'irregular' practices, especially among the middle classes, to greater openness. The article uses a variety of sources, including the records of the National Council for the Unmarried Mother and Her Child (founded in 1918, now One Parent Families), oral histories, contemporary interviews and official and unofficial investigations.

  12. Immigration, crime, and incarceration in early twentieth-century America.

    Science.gov (United States)

    Moehling, Carolyn; Piehl, Anne Morrison

    2009-11-01

    The major government commissions on immigration and crime in the early twentieth century relied on evidence that suffered from aggregation bias and the absence of accurate population data, which led them to present partial and sometimes misleading views of the immigrant-native criminality comparison. With improved data and methods, we find that in 1904, prison commitment rates for more serious crimes were quite similar by nativity for all ages except ages 18 and 19, for which the commitment rate for immigrants was higher than for the native-born. By 1930, immigrants were less likely than natives to be committed to prisons at all ages 20 and older, but this advantage disappears when one looks at commitments for violent offenses. The time series pattern reflects a growing gap between natives and immigrants at older ages, one that was driven by sharp increases in the commitment rates of the native-born, while commitment rates for the foreign-born were remarkably stable.

  13. Exhibition: Linus Pauling and the Twentieth Century

    CERN Document Server

    2003-01-01

    On April 28 the exhibit Linus Pauling and the Twentieth Century organised by UNIDIR (United Nations Institute for Disarmament Research) and SGI (Soka Gakkai International) as well as with the contributions of CERN and the University of Geneva, opened at the United Nations Office of Geneva. Linus Pauling is the only person to date to have won two unshared Nobel Prizes: Chemistry in 1954 and Peace in 1962. The first was awarded for his landmark research on the nature of the chemical bond and its application in understanding the structure of complex substances. The second one acknowledged his courageous protest against atmospheric nuclear testing and his championship of international peace. The exhibit, for audience of all ages, traces seven decades of Linus Pauling's life and influence on the 20th century. Before starting its European tour at the UNESCO headquarters in Paris, the exhibit opened in 1998 in San Francisco and then travelled within the United-States and to Japan with an attendance of more than one...

  14. Exhibition: Linus Pauling and the Twentieth Century

    CERN Multimedia

    2003-01-01

    On April 28 the exhibit Linus Pauling and the Twentieth Century organised by UNIDIR (United Nations Institute for Disarmament Research) and SGI (Soka Gakkai International) as well as with the contributions of CERN and the University of Geneva, opens at the United Nations Office of Geneva. Linus Pauling is the only person to date to have won two unshared Nobel Prizes: Chemistry in 1954 and Peace in 1962. The first was awarded for his landmark research on the nature of the chemical bond and its application in understanding the structure of complex substances. The second one acknowledged his courageous protest against atmospheric nuclear testing and his championship of international peace. The exhibit, for all ages' audiences, traces seven decades of Linus Pauling's life and influence on the 20th century. Before starting its European tour at the UNESCO headquarters in Paris, the exhibit opened in 1998 in San Francisco and then travelled within the United-States and to Japan with an attendance of more than one m...

  15. Redrawing the map: science in twentieth-century China.

    Science.gov (United States)

    Fan, Fa-ti

    2007-09-01

    This essay argues that science in twentieth-century China is a rich topic that can be productively integrated into research and teaching on the history of modern science. It identifies major issues of science in twentieth-century China and demonstrates that they can prove useful to any scholar who wishes to consider science in a comparative and trans/international context. The essay suggests two important steps for a fruitful investigation into the topic of science in twentieth-century China: first, revising the historiographic assumptions and categories that underlie much of the conventional historical narrative of modern science; and, second, breaking free from the tunnel history of national science. To illustrate these points, the essay examines a series of case studies of science in modern China and discusses the relevance of such subjects as scientific nationalism, Maoist mass science, and transnational scientific networks for the understanding of science in the twentieth-century world.

  16. Urban Forms and Civic Space in Nineteenth to Early Twentieth Century Bangkok and Rangoon

    OpenAIRE

    Moore, Elizabeth Howard; Osiri, Navanath

    2013-01-01

    Buddhist spaces in Bangkok and Rangoon both had long common traditions prior to nineteenth and early twentieth-century colonial incursions. Top–down central city planning with European designs transformed both cities. While Siamese kings personally initiated civic change that began to widen economic and social interaction of different classes, British models segregated European, Burmese, Indian, and Chinese populations to exacerbate social differences. In addition, the Siamese rulers maintain...

  17. Imagining the Twentieth Century: Retrospective, Myth, and the Colonial Question

    Directory of Open Access Journals (Sweden)

    David B MacDonald

    2007-01-01

    Full Text Available Retrospectives on the twentieth century often portray it as the most atrocious century in human history, in terms of totalising ideologies, moral abandonment, technological horror, and mass death. The nineteenth and earlier centuries, by contrast, emerge as progressive and enlightened eras, characterised by morality, rationalism, and the absence of war. Creating a dramatic contrast between old and new centuries ignores the historical reality of colonialism and violence outside Europe’s borders. This article problematises twentieth century retrospectives and their nostalgia for the past, comparing these with recent histories of colonialism and genocide. Rather than see the twentieth century as a decisive break from the past, there are important elements of continuity and evolution which should not be ignored.

  18. Stress, Shock, and Adaptation in the Twentieth Century

    DEFF Research Database (Denmark)

    Leese, Peter

    2016-01-01

    Review article on: David Cantor and Edmund Ramsden, eds. Stress, Shock, and Adaptation in the Twentieth Century. Rochester Studies in Medical History. Rochester, N.Y.: University of Rochester Press, 2014. vi + 367 pp. Ill. $125.00 (978-1-58046-476-5).......Review article on: David Cantor and Edmund Ramsden, eds. Stress, Shock, and Adaptation in the Twentieth Century. Rochester Studies in Medical History. Rochester, N.Y.: University of Rochester Press, 2014. vi + 367 pp. Ill. $125.00 (978-1-58046-476-5)....

  19. The Twentieth-Century Sea Level Budget: Recent Progress and Challenges

    Science.gov (United States)

    Jevrejeva, S.; Matthews, A.; Slangen, A.

    2017-01-01

    For coastal areas, given the large and growing concentration of population and economic activity, as well as the importance of coastal ecosystems, sea level rise is one of the most damaging aspects of the warming climate. Huge progress in quantifying the cause of sea level rise and closure of sea level budget for the period since the 1990s has been made mainly due to the development of the global observing system for sea level components and total sea levels. We suggest that a large spread (1.2 ± 0.2-1.9 ± 0.3 mm year-1) in estimates of sea level rise during the twentieth century from several reconstructions demonstrates the need for and importance of the rescue of historical observations from tide gauges, with a focus on the beginning of the twentieth century. Understanding the physical mechanisms contributing to sea level rise and controlling the variability of sea level over the past few 100 years are a challenging task. In this study, we provide an overview of the progress in understanding the cause of sea level rise during the twentieth century and highlight the main challenges facing the interdisciplinary sea level community in understanding the complex nature of sea level changes.

  20. Mythologies and Panics: Twentieth Century Constructions of Child Prostitution

    Science.gov (United States)

    Brown, Alyson

    2004-01-01

    This paper examines twentieth century social constructions of child prostitutes and child prostitution, the origins of these representations and the extent to which they have been used as metaphors for other perceived social, economic and political problems. It is important to recognise that these children have been sexually abused and that…

  1. Outdoor Physical Education in French Schools during the Twentieth Century

    Science.gov (United States)

    Attali, Michaël; Saint-Martin, Jean

    2017-01-01

    During the twentieth century, outdoor physical education (OPE) gradually integrated with the French education system. Culturally speaking, OPE had to overcome several hurdles because it promoted values such as freedom, initiative and responsibility that were deemed incompatible with the existing educational model. Beyond being a pedagogical tool,…

  2. Mythologies and Panics: Twentieth Century Constructions of Child Prostitution

    Science.gov (United States)

    Brown, Alyson

    2004-01-01

    This paper examines twentieth century social constructions of child prostitutes and child prostitution, the origins of these representations and the extent to which they have been used as metaphors for other perceived social, economic and political problems. It is important to recognise that these children have been sexually abused and that…

  3. A New Teacher for a New Nation? Teacher Education, "English", and Schooling in Early Twentieth-Century Australia

    Science.gov (United States)

    Green, Bill; Reid, Jo-Anne

    2012-01-01

    The late nineteenth-century expansion of public schooling in Australia from an initial focus on the elementary phase to post-primary provision, and then to a more systematic secondary education over the early to mid-twentieth century, went hand in hand with the emergence of new populations of children and young people--a new constituency. In turn,…

  4. "Strong Mothers Make Strong Children": Sports, Eugenics and Nationalism in Brazil at the Beginning of the Twentieth Century

    Science.gov (United States)

    Goellner, Silvana Vilodre; Votre, Sebastiao Josue; Pinheiro, Maria Claudia Brandao

    2012-01-01

    Based on post-structural feminist and gender studies, the present article analyses the importance given to the practice of physical education, sports and exercise as part of the national policy to strengthen the Caucasian-Brazilian population at the beginning of the twentieth century, emphasising the priority made of the White female body as the…

  5. Neonatal mortality and stillbirths in early twentieth century Derbyshire, England.

    Science.gov (United States)

    Reid, A

    2001-11-01

    Neonatal mortality and stillbirths are recognised to be subject to similar influences, but survival after a successful live birth is usually considered in isolation of foetal wastage. Moreover, individual-level data on age-specific influences and causes of death in a historical context are rare. This paper uses an unusual data set to compare the influences on neonatal mortality and stillbirths in early twentieth century Derbyshire, England. Multivariate hazard and logistic analyses are performed to examine the relative roles of various social, environmental, and demographic factors. The influences on and causal structures of neonatal mortality and stillbirths emerge as broadly similar, with previous reproductive history linked to a considerable amount of variation. The clustering of endogenous deaths was much greater than the clustering of exogenous and post-neonatal deaths, probably reflecting the cause-of-death structure and the relatively healthy social and environmental position of early twentieth century Derbyshire.

  6. Javanese Women and Islam: Identity Formation since the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Kurniawati Hastuti Dewi

    2011-04-01

    Full Text Available Despite the vast research over the last three decades devoted to the lives and social interaction of Javanese women, little has been written on the formation of these women’s identity by focusing on its development from the twentieth century up to the early twenty-first. This paper endeavors to show that the religio-cultural identity of Javanese women was forged through a number of sociocultural circumstances. While revealing different features of the relationship between Javanese women and Islam, I shed light on the role Islam played, particularly since the early twentieth century, in providing transformative power to the role and status of Javanese Muslim women, manifested by the adoption of such Islamic dress codes as veiling, as also an important means of identity politics. I argue that new Islamic discourses have always been born out of the desire to challenge the conservative understanding of the role and status of Javanese women in different historical periods.

  7. Probabilistic reanalysis of twentieth-century sea-level rise

    Science.gov (United States)

    Hay, Carling C.; Morrow, Eric; Kopp, Robert E.; Mitrovica, Jerry X.

    2015-01-01

    Estimating and accounting for twentieth-century global mean sea-level (GMSL) rise is critical to characterizing current and future human-induced sea-level change. Several previous analyses of tide gauge records--employing different methods to accommodate the spatial sparsity and temporal incompleteness of the data and to constrain the geometry of long-term sea-level change--have concluded that GMSL rose over the twentieth century at a mean rate of 1.6 to 1.9 millimetres per year. Efforts to account for this rate by summing estimates of individual contributions from glacier and ice-sheet mass loss, ocean thermal expansion, and changes in land water storage fall significantly short in the period before 1990. The failure to close the budget of GMSL during this period has led to suggestions that several contributions may have been systematically underestimated. However, the extent to which the limitations of tide gauge analyses have affected estimates of the GMSL rate of change is unclear. Here we revisit estimates of twentieth-century GMSL rise using probabilistic techniques and find a rate of GMSL rise from 1901 to 1990 of 1.2 +/- 0.2 millimetres per year (90% confidence interval). Based on individual contributions tabulated in the Fifth Assessment Report of the Intergovernmental Panel on Climate Change, this estimate closes the twentieth-century sea-level budget. Our analysis, which combines tide gauge records with physics-based and model-derived geometries of the various contributing signals, also indicates that GMSL rose at a rate of 3.0 +/- 0.7 millimetres per year between 1993 and 2010, consistent with prior estimates from tide gauge records. The increase in rate relative to the 1901-90 trend is accordingly larger than previously thought; this revision may affect some projections of future sea-level rise.

  8. Mustaches and masculine codes in early twentieth-century America.

    Science.gov (United States)

    Oldstone-Moore, Christopher

    2011-01-01

    The purpose of this article is to deepen our understanding of twentieth-century masculinity by considering the social function of facial hair. The management of facial hair has always been a medium of gendered body language, and as such has elicited a nearly continuous private and public conversation about manliness. Careful attention to this conversation, and to trends in facial hairstyles, illuminates a distinct and consistent pattern of thought about masculinity in early twentieth-century America. The preeminent form of facial hair - mustaches - was used to distinguish between two elemental masculine types: sociable and autonomous. A man was neither wholly one nor the other, but the presence and size of a mustache - or its absence - served to move a man one way or another along the continuum that stretched from one extreme to the other. According to the twentieth-century gender code, a clean-shaven man's virtue was his commitment to his male peers and to local, national or corporate institutions. The mustached man, by contrast, was much more his own man: a patriarch, authority figure or free agent who was able to play by his own rules. Men and women alike read these signals in their evaluation of men.

  9. City-size distributions and the world urban system in the twentieth century.

    Science.gov (United States)

    Ettlinger, N; Archer, J C

    1987-09-01

    "In this paper we trace and interpret changes in the geographical pattern and city-size distribution of the world's largest cities in the twentieth century. Since 1900 the geographical distribution of these cities has become increasingly dispersed; their city-size distribution by rank was nearly linear in 1900 and 1940, and convex in 1980. We interpret the convex distribution which emerged following World War 2 as reflecting an economically integrated but politically and demographically partitioned global urban system. Our interpretation of changes in size distribution of cities emphasizes demographic considerations, largely neglected in previous investigations, including migration and relative rates of population change."

  10. Twentieth century Walker Circulation change: data analysis and model experiments

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Qingjia [Leibniz-Institut fuer Meereswissenschaften, Kiel (Germany); Chinese Research Academy of Environmental Sciences, River and Coastal Environment Research Center, Beijing (China); Chinese Academy of Sciences, Key Laboratory of Ocean Circulation and Waves, Institute of Oceanology, Qingdao (China); Latif, Mojib; Park, Wonsun; Keenlyside, Noel S.; Martin, Thomas [Leibniz-Institut fuer Meereswissenschaften, Kiel (Germany); Semenov, Vladimir A. [Leibniz-Institut fuer Meereswissenschaften, Kiel (Germany); A.M. Obukhov Institute of Atmospheric Physics, Russian Academy of Sciences, Moscow (Russian Federation)

    2012-05-15

    Recent studies indicate a weakening of the Walker Circulation during the twentieth century. Here, we present evidence from an atmospheric general circulation model (AGCM) forced by the history of observed sea surface temperature (SST) that the Walker Circulation may have intensified rather than weakened. Observed Equatorial Indo-Pacific Sector SST since 1870 exhibited a zonally asymmetric evolution: While the eastern part of the Equatorial Pacific showed only a weak warming, or even cooling in one SST dataset, the western part and the Equatorial Indian Ocean exhibited a rather strong warming. This has resulted in an increase of the SST gradient between the Maritime Continent and the eastern part of the Equatorial Pacific, one driving force of the Walker Circulation. The ensemble experiments with the AGCM, with and without time-varying external forcing, suggest that the enhancement of the SST gradient drove an anomalous atmospheric circulation, with an enhancement of both Walker and Hadley Circulation. Anomalously strong precipitation is simulated over the Indian Ocean and anomalously weak precipitation over the western Pacific, with corresponding changes in the surface wind pattern. Some sensitivity to the forcing SST, however, is noticed. The analysis of twentieth century integrations with global climate models driven with observed radiative forcing obtained from the Coupled Model Intercomparison Project (CMIP) database support the link between the SST gradient and Walker Circulation strength. Furthermore, control integrations with the CMIP models indicate the existence of strong internal variability on centennial timescales. The results suggest that a radiatively forced signal in the Walker Circulation during the twentieth century may have been too weak to be detectable. (orig.)

  11. Global SST influence on twentieth century NAO variability

    Energy Technology Data Exchange (ETDEWEB)

    Paeth, H.; Hense, A. [Meteorologisches Institut, Universitaet Bonn, 53121 Bonn (Germany); Latif, M. [Max-Planck-Institut fuer Meteorologie, 20146 Hamburg (Germany)

    2003-07-01

    Recent studies have suggested that sea surface temperature (SST) is an important source of variability of the North Atlantic Oscillation (NAO). Here, we deal with four basic aspects contributing to this issue: (1) we investigate the characteristic time scales of this oceanic influence; (2) quantify the scale-dependent hindcast potential of the NAO during the twentieth century as derived from SST-driven atmospheric general circulation model (AGCM) ensembles; (3) the relevant oceanic regions are identified, corresponding SST indices are defined and their relationship to the NAO are evaluated by means of cross spectral analysis and (4) our results are compared with long-term coupled control experiments with different ocean models in order to ensure whether the spectral relationship between the SST regions and the NAO is an intrinsic mode of the coupled climate system, involving the deep ocean circulation, rather than an artefact of the unilateral SST forcing. The observed year-to-year NAO fluctuations are barely influenced by the SST. On the decadal time scales the major swings of the observed NAO are well reproduced by various ensembles from the middle of the twentieth century onward, including the negative state in the 1960s and part of the positive trend afterwards. A six-member ECHAM4-T42 ensemble reveals that the SST boundary condition affects 25% of total decadal-mean and interdecadal-trend NAO variability throughout the twentieth century. The most coherent NAO-related SST feature is the well-known North Atlantic tripole. Additional contributions may arise from the southern Pacific and the low-latitude Indian Ocean. The coupled climate model control runs suggest only the North Atlantic SST-NAO relationship as being a true characteristic of the coupled climate system. The coherence and phase spectra of observations and coupled simulations are in excellent agreement, confirming the robustness of this decadal-scale North Atlantic air-sea coupled mode. (orig.)

  12. The riddle of sex: biological theories of sexual difference in the early twentieth-century.

    Science.gov (United States)

    Ha, Nathan Q

    2011-01-01

    At the turn of the twentieth century, biologists such as Oscar Riddle, Thomas Hunt Morgan, Frank Lillie, and Richard Goldschmidt all puzzled over the question of sexual difference, the distinction between male and female. They all offered competing explanations for the biological cause of this difference, and engaged in a fierce debate over the primacy of their respective theories. Riddle propounded a metabolic theory of sex dating from the late-nineteenth century suggesting that metabolism lay at the heart of sexual difference. Thomas Hunt Morgan insisted on the priority of chromosomes, Frank Lillie emphasized the importance of hormones, while Richard Goldschmidt supported a mixed model involving both chromosomes and hormones. In this paper, I will illustrate how the older metabolic theory of sex was displaced when those who argued for the relatively newer theories of chromosomes and hormones gradually formed an alliance that accommodated each other and excluded the metabolic theory of sex. By doing so, proponents of chromosomes and hormones established their authority over the question of sexual difference as they laid the foundations for the new disciplines of genetics and endocrinology. Their debate raised urgent questions about what constituted sexual difference, and how scientists envisioned the plasticity and controllability of this difference. These theories also had immediate political and cultural consequences at the turn of the twentieth century, especially for the eugenic and feminist movements, both of which were heavily invested in knowledge of sex and its determination, ascertainment, and command.

  13. The Long Twentieth Century and Barriers to China's Hegemonic Accession

    Directory of Open Access Journals (Sweden)

    John Gulick

    2015-08-01

    Full Text Available Giovanni Arrighi's The Long Twentieth Century is an almost unfathomably ambitious andcomplex work. Its monumentality derives from Arrighi 's conviction that the best way to handicapthe possible futures of the world capitalist geo-economy is to analyze the structural evolution ofthis global system, an evolution spanning more than five centuries; the genius of the work rests inthe distinctive approach that Arrighi takes. At the core of his approach is the identification ofthose long-term trends and accreted characteristics - one might call them "systemiccontradictions" - that promise to send the world capitalist geo-economy in a radically differentdevelopmental direction as US hegemony wanes. Arrighi 's assessment of these contradictionscompel him to make a provocative suggestion: in all likelihood, no singular concentration of stateand economic power possesses the territorial scale or the organizational capacities required tolead the global system through another round of restructuring and expansion. Properly framed,this illuminating insight could serve as the starting point for a theoretical exploration of thesocio-ecological constraints to global capitalist reproduction, but such is a journey (mostly nottaken by Arrighi in The Long Twentieth Century. In fact, to the degree that he subsequentlycontemplates the prospect of a China-centered reconstitution of the world geo-economy, Arrighimarginalizes the question of global systemic contradictions altogether.

  14. Twentieth-Century Leaders in the Moldovan History Textbooks

    Directory of Open Access Journals (Sweden)

    Sergiu Musteata

    2016-06-01

    Full Text Available The main research question of this paper is How the twentieth century leaders are treated in the History textbooks published within the last decade in the Republic of Moldova? The textbooks are a reflection of the History curriculum. Therefore, the analysis starts with the discussion of this document and its content concerning leaders and heroes. The main research sources are the History textbooks published in Moldova during the last decade that debate the events of the twentieth century. The paper analyses how the national, European and world leaders are treated in Moldovan textbooks, and how the discourse and the paradigm get changed depending on political regimes. Based on quantitative and qualitative methods, some conclusions have been made about various leaders, such as Lenin, Stalin, Hitler, Mussolini, Antonescu or leaders from the Cold War era. At the end, the leaders of independent Moldova are briefly presented too. As a result of this analysis we could see how the leaders are presented in the Moldovan textbooks and could conclude that the policy makers, textbook authors and publishers have to pay more attention to this topic.

  15. Height convergence and internal migration in mid-twentieth-century Italy.

    Science.gov (United States)

    Lanari, Donatella; Bussini, Odoardo

    2014-01-01

    Height convergence across Italian regions during the second half of the twentieth century is a widely recognized fact. However, it has been suggested that this process was partly affected by the massive migratory flow of people from southern to northern Italy in the 1950s and 1960s, which greatly slowed the height growth rate in the receiving regions, since immigrants were on average shorter than the receiving northern population. The main aims of this study were to estimate the speed of height convergence of Italian military conscripts in the second half of the twentieth century, and to estimate the contribution of internal migration from the south to the north of Italy to height convergence. We hypothesized that migrants from southern Italy reduced height levels among northerners relative to what they would have been without considering migration. We used cohort data on Italian conscripts born in 1951 and 1980. Results indicate that internal migration may explain from 24 to 32.7 percent of height convergence, meaning that ignoring migration flows yields an overestimation of the height changes for conscripts living in the south of Italy.

  16. Financial crises of the early twentieth century in Ukraine

    Directory of Open Access Journals (Sweden)

    S.Z. Moshenskyi

    2015-12-01

    Full Text Available The article analyzes the major financial crises in Ukraine at early twentieth century dealing with the crises of 1899–1902 and 1908–1910. The main attention is paid to the large-scale crisis of 1899–1902 at the new industrial region in Eastern Ukraine where numerous steel and mining companies based on massive foreign investment (mainly Belgian and French were created shortly. The general boom of new joint-stock companies and insufficient provision of these companies by state orders were the main reason of the crisis which was the reflection of the international industrial and financial crisis of those years. The author also researches the crisis of 1908–1910 in the Ukrainian sugar industry.

  17. John Stewart Bell and twentieth century physics vision and integrity

    CERN Document Server

    Whitaker, Andrew

    2016-01-01

    John Stewart Bell (1928-1990) was one of the most important figures in twentieth-century physics, famous for his work on the fundamental aspects of the century's most important theory, quantum mechanics. While the debate over quantum theory between the supremely famous physicists, Albert Einstein and Niels Bohr, appeared to have become sterile in the 1930s, Bell was able to revive it and to make crucial advances - Bell's Theorem or Bell's Inequalities. He was able to demonstrate a contradiction between quantum theory and essential elements of pre-quantum theory - locality and causality. The book gives a non-mathematical account of Bell's relatively impoverished upbringing in Belfast and his education. It describes his major contributions to quantum theory, but also his important work in the physics of accelerators, and nuclear and elementary particle physics.

  18. Climate of Hungary in the twentieth century according to Feddema

    Science.gov (United States)

    Ács, Ferenc; Breuer, Hajnalka; Skarbit, Nóra

    2015-01-01

    Feddema's (Physical Geography 26:442-466, 2005) bioclimatic classification scheme is applied to Hungary for the twentieth century using the Climatic Research Unit (CRU) data series. The method is tested in two modes. In the first, its original form is used which is suitable for global scale analysis. In the second, the criteria used in the method are slightly modified for mesoscale classification purposes. In both versions, potential evapotranspiration (PET) is calculated using McKenney and Rosenberg's (Meteorol 64:81-110, 1993) formula. We showed that McKenney and Rosenberg's formula could be applied to Hungary. According to Feddema's global scale application, local climates of the three main geographical regions, the Great Hungarian Plain, the North Hungarian Mountains, and Transdanubia, can be distinguished. However, the spatial distribution pattern within the regions is poorly reproduced, if at all. According to Feddema's mesoscale application, a picture of climatic subregions could be observed.

  19. Remembering and forgetting Freud in early twentieth-century dreams.

    Science.gov (United States)

    Forrester, John

    2006-03-01

    The paper explores the use of Freud's methods of dream interpretation by four English writers of the early twentieth century: T. H. Pear, W. H. R. Rivers, Ernest Jones, and Alix Strachey. Each employed their own dreams in rather different ways: as part of an assessment of Freud's work as a psychological theory, as illustrative of the cogency of Freud's method and theories as part of the psychoanalytic process. Each adopted different approaches to the question of privacy and decorum. The paper argues that assessment of the impact of Freud's work must take account of the application of the method to the researcher's own dreams and the personal impact this process of analysis had upon them, and must also gauge how the dreamers' deployment of Freud's methods influenced their explicit relationship to him and his theories.

  20. Of Sound Mind: Mental Distress and Sound in Twentieth-Century Media Culture

    NARCIS (Netherlands)

    Birdsall, Carolyn; Siewert, Senta

    2013-01-01

    abstractThis article seeks to specify the representation of mental disturbance in sound media during the twentieth century. It engages perspectives on societal and technological change across the twentieth century as crucial for aesthetic strategies developed in radio and sound film production. The

  1. Of Sound Mind: Mental Distress and Sound in Twentieth-Century Media Culture

    NARCIS (Netherlands)

    Birdsall, C.; Siewert, S.

    2013-01-01

    This article seeks to specify the representation of mental disturbance in sound media during the twentieth century. It engages perspectives on societal and technological change across the twentieth century as crucial for aesthetic strategies developed in radio and sound film production. The analysis

  2. Jung's very twentieth-century view of myth.

    Science.gov (United States)

    Segal, Robert A

    2003-11-01

    It is commonly assumed that Jung's view of myth, like his view of everything else, is best understood vis-à-vis Freud's. I argue that Jung in fact positions himself much more broadly, not merely against other psychologists of myth but more fundamentally against non-psychologists altogether. Undeniably, Jung pits his theory against Freud's, but only after pitting both his theory and Freud's against those theories that assume the subject matter of myth to be the external world rather than the human mind and that assume the function of myth to be either the explanation or the description of the external world rather than the expression of the human mind. The theorists whom Jung challenges are called 'nature mythologists', for whom myth is either a literal explanation or a symbolic description of the natural world. Which element of the natural world myth is about varies from nature mythologist to nature mythologist. The two leading nature mythologists, both of whom Jung cites, were Edward Tylor and James Frazer. Their theories epitomize the nineteenth-century approach to myth. For them, myth is the 'primitive' counterpart to science, which is entirely modern. For them, myth and science are incompatible, science is true and myth false, and myth must therefore go when science comes. Jung's rejection of the external world as the referent of myth and of explanation or description of that world as the function of myth epitomizes the twentieth-century response to nineteenth-century theories. For not merely Jung and Freud but also twentieth-century theorists generally, myth is anything but the 'primitive' counterpart to modern science. Consequently, myth and science are not rivals, so that myth need not go when science comes.

  3. Twentieth century ENSO-related precipitation mean states in twentieth century reanalysis, reconstructed precipitation and CMIP5 models

    Science.gov (United States)

    Dai, Ni; Arkin, Phillip A.

    2017-05-01

    El Niño-Southern Oscillation (ENSO)-related precipitation during the entire twentieth century is compared among the twentieth century reanalysis (20CR), a statistically reconstructed precipitation dataset (REC) and 30 Coupled Model Intercomparison Project Phase 5 (CMIP5) models. Empirical orthogonal functions, ENSO-related precipitation composites based on sea surface temperature (SST)-constructed ENSO index and singular value decomposition (SVD) are employed to extract ENSO-related precipitation/SST signals in each dataset. With the background trend being removed in all of the data, our results show that the REC and the 20CR resemble both in their precipitation climatology and ENSO-related precipitation results. The biases in the CMIP5 models precipitation climatology such as dry equator over the Pacific Ocean, "double-intertropical convergence zones (ITCZs)" and overly zonal Southern Pacific convergence zone (SPCZ) are major reasons for lowering spatial correlations with the REC and the 20CR precipitation climatology. Two groups of CMIP5 models are built based on severity of these biases in their precipitation background and the spatial correlations of ENSO-related precipitation with the observations. Compared with the group with more severe biases in its precipitation climatology, the group with smaller biases tends to produce more ENSO-like precipitation patterns, simulate more realistic mean magnitude and seasonal variability of ENSO precipitation signals, as well as generating better ENSO-related SST/precipitation correlation patterns produced in its SVD analysis. The ENSO-related precipitation biases in the CMIP5 models over the western Pacific and Indian Ocean, as well as the equatorial Pacific, are strongly related with their precipitation climatology biases over these regions. The ENSO-related precipitation biases over the off-equator eastern Pacific Ocean are associated with both the "double-ITCZs" biases in the precipitation climatology and the ENSO

  4. Twentieth century ENSO-related precipitation mean states in twentieth century reanalysis, reconstructed precipitation and CMIP5 models

    Science.gov (United States)

    Dai, Ni; Arkin, Phillip A.

    2016-07-01

    El Niño-Southern Oscillation (ENSO)-related precipitation during the entire twentieth century is compared among the twentieth century reanalysis (20CR), a statistically reconstructed precipitation dataset (REC) and 30 Coupled Model Intercomparison Project Phase 5 (CMIP5) models. Empirical orthogonal functions, ENSO-related precipitation composites based on sea surface temperature (SST)-constructed ENSO index and singular value decomposition (SVD) are employed to extract ENSO-related precipitation/SST signals in each dataset. With the background trend being removed in all of the data, our results show that the REC and the 20CR resemble both in their precipitation climatology and ENSO-related precipitation results. The biases in the CMIP5 models precipitation climatology such as dry equator over the Pacific Ocean, "double-intertropical convergence zones (ITCZs)" and overly zonal Southern Pacific convergence zone (SPCZ) are major reasons for lowering spatial correlations with the REC and the 20CR precipitation climatology. Two groups of CMIP5 models are built based on severity of these biases in their precipitation background and the spatial correlations of ENSO-related precipitation with the observations. Compared with the group with more severe biases in its precipitation climatology, the group with smaller biases tends to produce more ENSO-like precipitation patterns, simulate more realistic mean magnitude and seasonal variability of ENSO precipitation signals, as well as generating better ENSO-related SST/precipitation correlation patterns produced in its SVD analysis. The ENSO-related precipitation biases in the CMIP5 models over the western Pacific and Indian Ocean, as well as the equatorial Pacific, are strongly related with their precipitation climatology biases over these regions. The ENSO-related precipitation biases over the off-equator eastern Pacific Ocean are associated with both the "double-ITCZs" biases in the precipitation climatology and the ENSO

  5. Intellectual disability, mental illness and offending behaviour: forensic cases from early twentieth-century Ireland.

    Science.gov (United States)

    Kelly, B D

    2010-09-01

    The history of institutional care for individuals with intellectual disability is under-researched, complex and troubling. To explore the experiences of women who may have had intellectual disability and/or mental illness and were admitted to forensic psychiatric care in early twentieth-century Ireland. All female case records at the Central Mental Hospital, Dublin from 1910 to 1948 (n = 42) were studied for evidence of possible intellectual disability and a series of five cases is presented in detail. These committals occurred in the context of adverse social conditions, over-crowding in asylums and a belief that rates of mental illness were rising. Particular challenges included diagnostic issues (especially in relation to intellectual disability), adjustment to asylum environments, mental illness and physical ill-health. The institutional experiences of individuals with intellectual disability represents an important area for further historical research, using larger and more varied forensic populations.

  6. Memoirs a twentieth-century journey in science and politics

    CERN Document Server

    Teller, Edward

    2001-01-01

    The story of Edward Teller is the story of the twentieth century. Born in Hungary in 1908, Teller witnessed the rise of Nazism and anti-Semitism, two world wars, the McCarthy era, and the changing face of big science. A brilliant and controversial figure whose work on nuclear weapons was key to the American war effort, Teller has long believed in freedom through strong defense, a philosophy reflected in his stance on arms control and nuclear policy. These extraordinary recollections at last reveal the man behind the headlines-passionate and humorous, devoted and loyal. In clear and compelling prose, Teller tells of the people, events, and ideas that shaped him as a scientist, beginning with his early love of music and math, and continuing with his study of quantum physics with Werner Heisenberg. Present at many of the pivotal moments in modern science, Teller also describes his friendships with some of the century's greatest minds-Einstein, Bohr, Fermi, Szilard, von Neumann, Oppenheimer-and offers an honest a...

  7. Tropospheric circulation during the early twentieth century Arctic warming

    Science.gov (United States)

    Wegmann, Martin; Brönnimann, Stefan; Compo, Gilbert P.

    2016-06-01

    The early twentieth century Arctic warming (ETCAW) between 1920 and 1940 is an exceptional feature of climate variability in the last century. Its warming rate was only recently matched by recent warming in the region. Unlike recent warming largely attributable to anthropogenic radiative forcing, atmospheric warming during the ETCAW was strongest in the mid-troposphere and is believed to be triggered by an exceptional case of natural climate variability. Nevertheless, ultimate mechanisms and causes for the ETCAW are still under discussion. Here we use state of the art multi-member global circulation models, reanalysis and reconstruction datasets to investigate the internal atmospheric dynamics of the ETCAW. We investigate the role of boreal winter mid-tropospheric heat transport and circulation in providing the energy for the large scale warming. Analyzing sensible heat flux components and regional differences, climate models are not able to reproduce the heat flux evolution found in reanalysis and reconstruction datasets. These datasets show an increase of stationary eddy heat flux and a decrease of transient eddy heat flux during the ETCAW. Moreover, tropospheric circulation analysis reveals the important role of both the Atlantic and the Pacific sectors in the convergence of southerly air masses into the Arctic during the warming event. Subsequently, it is suggested that the internal dynamics of the atmosphere played a major role in the formation in the ETCAW.

  8. Aerological observations in the tropics in the early twentieth century

    Energy Technology Data Exchange (ETDEWEB)

    Broennimann, Stefan; Stickler, Alexander [Bern Univ. (Switzerland). Oeschger Centre for Climate Change Research and Inst. of Geography

    2013-10-15

    In the first decades of the 20{sup th} century, aerological observations were for the first time performed in tropical regions. One of the most prominent endeavours in this respect was Arthur Berson's aerological expedition to East Africa. Although the main target was the East African monsoon circulation, the expedition provided also other insights that profoundly changed meteorology and climatology. Berson observed that the tropical tropopause was much higher and colder than that over midlatitudes. Moreover, westerly winds were observed in the lower stratosphere, apparently contradicting the high-altitude equatorial easterly winds that were known since the Krakatoa eruption ('Krakatoa easterlies'). The puzzle was only resolved five decades later with the discovery of the Quasi-Biennial Oscillation (QBO). In this paper we briefly summarize the expedition of Berson and review the results in a historical context and in the light of the current research. In the second part of the paper we re-visit Berson's early aerological observations, which we have digitized. We compare the observed wind profiles with corresponding profiles extracted from the 'Twentieth Century Reanalysis', which provides global three-dimensional weather information back to 1871 based on an assimilation of sea-level and surface pressure data. The comparison shows a good agreement at the coast but less good agreement further inland, at the shore of Lake Victoria, where the circulation is more complex. These results demonstrate that Berson's observations are still valuable today as input to current reanalysis systems or for their validation. (orig.)

  9. Aerological observations in the Tropics in the Early Twentieth Century

    Directory of Open Access Journals (Sweden)

    Stefan Brönnimann

    2013-07-01

    Full Text Available In the first decades of the 20th century, aerological observations were for the first time performed in tropical regions. One of the most prominent endeavours in this respect was Arthur Berson's aerological expedition to East Africa. Although the main target was the East African monsoon circulation, the expedition provided also other insights that profoundly changed meteorology and climatology. Berson observed that the tropical tropopause was much higher and colder than that over midlatitudes. Moreover, westerly winds were observed in the lower stratosphere, apparently contradicting the high-altitude equatorial easterly winds that were known since the Krakatoa eruption (“Krakatoa easterlies(”. The puzzle was only resolved five decades later with the discovery of the Quasi-Biennial Oscillation (QBO. In this paper we briefly summarize the expedition of Berson and review the results in a historical context and in the light of the current research. In the second part of the paper we re-visit Berson's early aerological observations, which we have digitized. We compare the observed wind profiles with corresponding profiles extracted from the (“Twentieth Century Reanalysis(”, which provides global three-dimensional weather information back to 1871 based on an assimilation of sea-level and surface pressure data. The comparison shows a good agreement at the coast but less good agreement further inland, at the shore of Lake Victoria, where the circulation is more complex. These results demonstrate that Berson's observations are still valuable today as input to current reanalysis systems or for their validation.

  10. Quantum generations: a history of physics in the twentieth century

    Energy Technology Data Exchange (ETDEWEB)

    Rechenberg, H

    2000-11-01

    Full text: The author attempts to handle the most important physics development of the twentieth century, namely that of quantum theory, in one, not too bulky, volume. This heroic task is split into 29 chapters, each treating a topic that forms a well defined subpart of the big theme embracing quantum theory itself (and also some of its companions), and the experimental discoveries, technology, sociology and science politics connected with it. The contents of Part One cover roughly the first twenty years of the century. There are also chapters on the introduction of the quantum of action and atomic constitution, on discharge in gases, low-temperature research and the interaction of science with industrial and military affairs in World War I. Part Two, leading up to the Hiroshima bomb, includes, beyond such central chapters as the rise of nuclear physics, quantum field theory and the physical and philosophical interpretation of quantum mechanics, further accounts of the Eddington-Milne cosmology, physics in the dictatorial regimes of National Socialism, Fascism and Stalinism, and the intellectual immigration during the 1930s into the USA. Part Three brings the story up to the end of the century, embracing great topics like nuclear energy, Big Science (i.e. physics in military and civil projects), fundamental particle theories up to speculations about 'grand unification', quantum electronics, or the increasingly hostile attitude toward science in the past 30 years. The short Part Four contains two chapters on a century in retrospect, which was really the century of physics. An enormous amount of material has been addressed in this book, and one wonders how one person can say anything reasonable about all these topics. The overall organization and the selection of chapters appears to be well planned and carried out quite successfully. In this reviewer's opinion, some chapters, e.g. on Dirac's theoretical work or cosmology (on which the author has

  11. Diagnosis and authority in the early-twentieth-century medical practice of Richard C. Cabot.

    Science.gov (United States)

    Crenner, Christopher

    2002-01-01

    This paper examines diagnostic practices using the early twentieth-century medical literature and the patient correspondence and records from the clinic of Richard Cabot. What shaped medicine's rapidly growing persuasive authority in the twentieth century? Diagnostic expertise demonstrated the doctor's control over disease but offered a service of ambiguous value to patients. Cabot and his peers offered differing views on how new diagnostic techniques would influence their relationships to their patients. In his busy private clinic Cabot put into effect an exacting diagnostic process, modeled on his innovative Clinicopathological Conferences. The people who came to the clinic often sought his technical expertise but accepted his diagnostic practices and opinions sometimes only provisionally.

  12. The Rise of Obesity in Europe, A Twentieth Century Food History

    OpenAIRE

    Tenna Jensen

    2010-01-01

    The publication of ‘The rise of obesity in Europe. A twentieth century Food History’ is a contribution to the vast and recent literature produced on issues of food and alimentary changes in Europe. The edited volume is based on a symposium titled “From Under-nutrition to Obesity: Changes in Food Consumption in Twentieth-Century-Europe” held in September 2007 at SIFO (National Institute for Consumer Research) in Oslo.The volume contains a wide range of research traditions. Many fruitful debate...

  13. Industrial Characteristics and Employment of Older Manufacturing Workers in the Early-Twentieth-Century United States

    Science.gov (United States)

    Lee, Chulhee

    2015-01-01

    This study explores how industry-specific technological, organizational, and managerial features affected the employment of old male manufacturing workers in the early twentieth-century United States. Industrial characteristics favorably related to the employment of old industrial workers include high labor productivity, less capital- and material-intensive production, short workdays, low intensity of work, high job flexibility, and formalized employment relationship. Results show that aged industrial workers were heavily concentrated in “unfavorable” industries, suggesting that the contemporary argument of “industrial scrap heap” was applicable for most of the manufacturing workers in the early twentieth century United States. PMID:26989273

  14. A Sociological Look at Biofuels: Ethanol in the Early Decades of the Twentieth Century and Lessons for Today

    Science.gov (United States)

    Carolan, Michael S.

    2009-01-01

    This article develops a broad sociological understanding of why biofuels lost out to leaded gasoline as the fuel par excellence of the twentieth century, while drawing comparisons with biofuels today. It begins by briefly discussing the fuel-scape in the United States in the late nineteenth and early twentieth centuries, examining the farm…

  15. A Sociological Look at Biofuels: Ethanol in the Early Decades of the Twentieth Century and Lessons for Today

    Science.gov (United States)

    Carolan, Michael S.

    2009-01-01

    This article develops a broad sociological understanding of why biofuels lost out to leaded gasoline as the fuel par excellence of the twentieth century, while drawing comparisons with biofuels today. It begins by briefly discussing the fuel-scape in the United States in the late nineteenth and early twentieth centuries, examining the farm…

  16. Benjamin Moore, Science, and Medical Planning in Early Twentieth-Century Britain

    Science.gov (United States)

    Lawson, Gordon S.

    2008-01-01

    Benjamin Moore (1867-1922), physiologist and biochemist, was an eminent member of the British scientific and medical community in the early twentieth century. As a founder and president of the State Medical Services Association (SMSA) from its establishment in 1912 until his untimely death in 1922, Moore was a prominent medical services activist…

  17. Sociology of Twentieth Century Congregate Care of the Developmentally Disabled-Recollections

    Science.gov (United States)

    Daly, William C.

    2005-01-01

    Elements of the twentieth century care facility of state origin are enumerated as the reader hopefully gets some idea of the social milieu or ethos of that period and the management profile thought to be proper and expeditious for unfortunate, homeless and poorly adjusted citizens. The life of staff and patients within these state sponsored…

  18. Translation, Hybridization, and Modernization: John Dewey and Children's Literature in Early Twentieth Century China

    Science.gov (United States)

    Xu, Xu

    2013-01-01

    This essay examines how John Dewey's child-centered educational philosophy was adopted and adapted in the early twentieth century in China to create a Chinese children's literature. Chinese intellectuals applied Dewey's educational philosophy, which values children's interests and needs, to formulate a new concept of modern childhood that…

  19. Singing the Nation into Being: Teaching Identity and Culture at the Turn of the Twentieth Century

    Science.gov (United States)

    Sargeant, Lynn M.

    2009-01-01

    In this article, the author compares the music education in the United States and the Russian Empire at the turn of the twentieth century. In both countries, music educators struggled to secure a permanent role for vocal music in the school. By comparing Russian music instruction to that in the United States, educators can better understand not…

  20. Westward Bound? Dutch Education and Cultural Transfer in the Mid-Twentieth Century

    Science.gov (United States)

    Bakker, Nelleke

    2014-01-01

    This article discusses the transition from philosophy to psychology as the main source of inspiration for education during the mid-twentieth century in the Netherlands, situated between Germany in the east and the English-speaking world in the west. Claims have been made that educational theory in the Netherlands was dominated by German philosophy…

  1. Widening horizons?: the geography of the marriage market in nineteenth and early-twentieth century Netherlands

    NARCIS (Netherlands)

    Ekamper, P.; van Poppel, F.W.A.; Mandemakers, K.; P. Gutmann, Myron; D. Deane, Glenn; R. Merchant, Emily; M. Sylvester, Kenneth

    2011-01-01

    Historical studies suggest that nineteenth- and twentieth-century processes of national integration in the countries of Western Europe fundamentally changed interactions between individuals living in different parts of those countries. These studies, however, were rarely able to provide direct evide

  2. Conceptual Revolutions in Twentieth-Century Art. NBER Working Paper No. 15073

    Science.gov (United States)

    Galenson, David

    2009-01-01

    Art critics and scholars have acknowledged the breakdown of their explanations and narratives of contemporary art in the face of what they consider the incoherent era of "pluralism" or "postmodernism" that began in the late twentieth century. This failure is in fact a result of their inability to understand the nature of the development of…

  3. Science, occultism, and the art of the avant-garde in the early twentieth century

    NARCIS (Netherlands)

    Bauduin, T.M.

    2012-01-01

    In the early twentieth century, scientific discoveries such as n-dimensionality, x-rays, and electromagnetism made their way into the discourse of Occultism, where they were subsequently reframed as the occult fourth dimension, clairvoyant x-ray vision, and thought vibration. As this article will sh

  4. "Are You Only an Applauder?" American Music Correspondence Schools in the Early Twentieth Century

    Science.gov (United States)

    Vogel, Dorothy

    2015-01-01

    The purpose of this study was to examine correspondence schools of music in the early twentieth century. Advertisements in widely circulated household and music periodicals and archival copies of courses from Siegel-Myers Correspondence School of Music, United States School of Music, American College of Music, and others were examined. Research…

  5. Scholarly Publishing: Books, Journals, Publishers, and Libraries in the Twentieth Century.

    Science.gov (United States)

    Abel, Richard E., Ed.; Newlin, Lyman W., Ed.

    2002-01-01

    In this volume, publishers, booksellers, journal dealers, and librarians share their views on libraries and publishing. While the information/knowledge transfer process in the entire span of the twentieth century was to be addressed by the contributors, the principal focus of every author was to be the last five decades in which the most profound,…

  6. Harmonisation and South African Languages: Twentieth Century Debates of Homogeneity and Heterogeneity

    Science.gov (United States)

    Heugh, Kathleen

    2016-01-01

    This article offers a historiographic analysis of twentieth century debates amongst agents with linguistic, missionary and ideological interest in the standardisation or harmonisation of two widely used clusters of languages in South Africa, Nguni and Sotho. The discussion illustrates how faith-based and political ideologies interact with and…

  7. Educational Testing as an Accountability Measure: Drawing on Twentieth-Century Danish History of Education Experiences

    Science.gov (United States)

    Ydesen, Christian

    2013-01-01

    This article reveals perspectives based on experiences from twentieth-century Danish educational history by outlining contemporary, test-based accountability regime characteristics and their implications for education policy. The article introduces one such characteristic, followed by an empirical analysis of the origins and impacts of test-based…

  8. Intertransitions between Islam and Eastern Orthodoxy in Kazakhstan (Nineteenth-Early Twentieth Centuries)

    Science.gov (United States)

    Sadvokasova, Zakish T.; Orazbayeva, Altynay I.

    2016-01-01

    The purpose of this paper is to review the historical facts related to conversion of indigenous people of the Kazakh steppe from Islam to Christianity and the conversion of the Russian migrants from Orthodoxy to Islam in Kazakhstan in the nineteenth-early twentieth century. The study deals with the laws that were detrimental to Islam and reforms…

  9. Teaching the French Revolution: Lessons and Imagery from Nineteenth and Twentieth Century Textbooks

    Science.gov (United States)

    Harison, Casey

    2002-01-01

    This article considers the "myths" and negative images of the French Revolution which were fashioned in the United States by examining interpretations found in nineteenth and twentieth-century American school texts. The texts are part of the Floyd Family Collection at Indiana State University, representing books used in Indiana schools,…

  10. "Are You Only an Applauder?" American Music Correspondence Schools in the Early Twentieth Century

    Science.gov (United States)

    Vogel, Dorothy

    2015-01-01

    The purpose of this study was to examine correspondence schools of music in the early twentieth century. Advertisements in widely circulated household and music periodicals and archival copies of courses from Siegel-Myers Correspondence School of Music, United States School of Music, American College of Music, and others were examined. Research…

  11. No issue, no problem? Co-education in dutch secondary physical education during the twentieth century

    NARCIS (Netherlands)

    van Essen, H.W.

    2003-01-01

    This article places the current state of Dutch co-education in physical education into a longitudinal perspective. Occasionally, comparisons are made with Germany and England. The dominant, twentieth-century, co-educational tradition in the Netherlands including its pragmatic argumentation has influ

  12. Harbingers of Feminism? Gender, Cultural Capital and Education in Mid-Twentieth-Century Rural Wales

    Science.gov (United States)

    Baker, Sally; Brown, Brian

    2009-01-01

    This paper reports the results of a small-scale narrative study of men and women who grew up in mid-twentieth-century rural Wales, and their reminiscences regarding women and education. Although the dominant image of Wales during that era is that of a male-dominated society, all of our participants remembered influential independent women and…

  13. Twentieth-Century Transformation in Catalonia and the Ukraine: Ethnic Implications in Education.

    Science.gov (United States)

    Petherbridge-Hernandez, Patricia; Raby, Rosalind Latiner

    1993-01-01

    Traces the parallel histories of cultural and language preservation in the minority regions of Catalonia (Spain) and Ukraine (former Soviet Union) during the twentieth century. Discusses large societal changes, national government policies about language of instruction, bilingual education, the comparative status of Catalan and Ukrainian, and…

  14. Intellectual Portraits: Politics, Professions and Identity in Twentieth-Century England

    Science.gov (United States)

    Martin, Jane

    2014-01-01

    This article brings together six talented women historians in twentieth-century England whose scholarly productions helped shape modern historical practice but who are little known in the canonical accounts of history-writing in the period. The author is looking to map and describe historical communities from a grounded and qualitative perspective…

  15. Regional Variation and Convergence of Height and Living Conditions in Sweden During the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Stefan Öberg

    2017-04-01

    Full Text Available This study investigates regional differences in height in Sweden during the twentieth century using data from universal conscript inspections (for men. We find substantive differences (2-3 cm in height between the counties. Men in the southern, southeastern and northernmost parts of Sweden were shorter. Men in the Stockholm and Göteborg regions were taller and we find no “urban penalty” in height. The differences in height between counties declined over the course of the twentieth century and the average height increased more in the counties with an initially shorter average height. We find the expected positive associations between height and the real wage in manufacturing and the regional GDP per capita respectively. The real wage in the manufacturing sector is more consistently associated with the county average height than that for the agricultural sector. Contrary to expectations, we find that the men were consistently taller in counties with higher food prices and where the relative price of animal foods was higher. The average height was negatively associated with the infant mortality rate during the men’s childhood in the mid-twentieth century. The association was less clear in the early twentieth century.

  16. No issue, no problem? Co-education in dutch secondary physical education during the twentieth century

    NARCIS (Netherlands)

    van Essen, H.W.

    This article places the current state of Dutch co-education in physical education into a longitudinal perspective. Occasionally, comparisons are made with Germany and England. The dominant, twentieth-century, co-educational tradition in the Netherlands including its pragmatic argumentation has

  17. Slope processes and related risk appearance within the Icelandic Westfjords during the twentieth century

    Directory of Open Access Journals (Sweden)

    A. Decaulne

    2005-01-01

    Full Text Available In North-western Iceland, records of slope processes were increasing during the twentieth century. Few dramatic events during the last decades highlighted the danger due to slope dynamics, leaving local populations in a risk situation that was merely unknown before 1970. The recent snow-avalanche, debris-flow and rock-fall activity underlined that the most frequent processes are not these with the largest human impact. In fact, the most catastrophic events were the extreme ones, following directly from a low frequency and a high magnitude. The purpose of this paper is to draw a parallel history of natural hazard and residence spatial extension, for an accurate understanding of the present-day risk situation, as the population growth markedly increased during the same time. Different quantitative and qualitative methods are applied. Geomorphological investigations locate the main threaten areas, in the path of slope processes release evidences, i.e. suitable slope morphology and/or inherited/actual forms. By a collection of dating data, as historic records and lichenometrical analysis, the frequency of given magnitude events is known. Climatic analysis clarifies the triggering meteorological conditions of slope processes and offers an overview of climate fluctuation during the investigated period; wind speed and direction is critical to hazardous snow-avalanche departure and snowmelt is crucial for debris-flow release. The findings clearly indicate that a combination of spatial expansion of inhabited areas and a lack of slope processes knowledge at the expansion time led to a recent and progressive risk appearance due to snow avalanches (including slush flows, debris flows and rock fall in most towns and villages of North-western Iceland.

  18. A historical synopsis of farm animal disease and public policy in twentieth century Britain.

    Science.gov (United States)

    Woods, Abigail

    2011-07-12

    The diseases suffered by British livestock, and the ways in which they were perceived and managed by farmers, vets and the state, changed considerably over the course of the twentieth century. This paper documents and analyses these changes in relation to the development of public policy. It reveals that scientific knowledge and disease demographics cannot by themselves explain the shifting boundaries of state responsibility for animal health, the diseases targeted and the preferred modes of intervention. Policies were shaped also by concerns over food security and the public's health, the state of the national and livestock economy, the interests and expertise of the veterinary profession, and prevailing agricultural policy. This paper demonstrates how, by precipitating changes to farming and trading practices, public policy could sometimes actually undermine farm animal health. Animal disease can therefore be viewed both as a stimulus to, and a consequence of, twentieth century public policy.

  19. New perspectives on forced migration in the history of twentieth-century neuroscience.

    Science.gov (United States)

    Stahnisch, Frank W; Russell, Gül

    2016-01-01

    This special issue of the Journal of the History of the Neurosciences, comprised of six articles and one commentary, reflects on the multifold dimensions of intellectual migration in the neurosciences and illustrates them by relevant case studies, biographies, and surveys from twentieth-century history of science and medicine perspectives. The special issue as a whole strives to emphasize the impact of forced migration in the neurosciences and psychiatry from an interdisciplinary perspective by, first, describing the general research topic, second, by showing how new models can be applied to the historiography and social studies of twentieth-century neuroscience, and, third, by providing a deeper understanding of the impact of European émigré researchers on emerging allied fields, such as neurogenetics, biological psychiatry, psychosomatics, and public mental health, etc. as resulting from this process at large.

  20. Oral history, subjectivity, and environmental reality: occupational health histories in twentieth-century Scotland.

    Science.gov (United States)

    Johnston, Ronnie; McIvor, Arthur

    2004-01-01

    This essay uses oral histories of dust disease in twentieth-century Scotland to illustrate the ways in which such history can illuminate how the working environment and work cultures affect workers' bodies and how workers come to terms with the ill-health caused by their employment. It emphasizes the agency of the interpreter but argues further that oral histories of dust disease in twentieth-century Scotland are simultaneously influenced by, and evidence for, material conditions. The essay explores the notion that the bodies, not just the voices of interviewees, are material testament to health-corroding work practices, cultures, and habitat. The focus is the problems caused by the inhalation of coal and asbestos dust.

  1. The dearth of the clinic: lead, air, and agency in twentieth-century America.

    Science.gov (United States)

    Sellers, Christopher

    2003-07-01

    By surveying myriad ways that twentieth-century American experts and nonexperts grappled with the health implications of aerial exposures to lead or substances that may have contained lead, this paper urges medical historians' attention toward environments-workplaces, homes and the outdoors-and their extrabodily ontology. Health histories framed around dust, toxins, fumes, and pollution rather than around particular diseases challenge long-accepted narratives, such as Hibbert Hill's old generalization about a "New Public Health" shift from "the environment to the individual." Greater environmental focus can also advance "bottom-up" health history. Pushing the gaze of twentieth-century medical and public health historians beyond hospitals, "public health" departments, clinically confirmable disease, and "patient" roles, it draws historians' attention to health-related realms in which laypeople often claimed greater knowledge and competence.

  2. Rabid epidemiologies: the emergence and resurgence of rabies in twentieth century South Africa.

    Science.gov (United States)

    Brown, Karen

    2011-01-01

    This article discusses the history of rabies in South Africa since the early twentieth century. It argues that rabies is a zoonotic disease that traverses rural and urban spaces, that transfers itself between wild and domestic animals and remains a potential threat to human life in the region. Scientists discovered an indigenous form of rabies, found primarily in the yellow mongoose, after the first biomedically confirmed human fatalities in 1928. Since the 1950s canine rabies, presumed to have moved southwards from across the Zambezi River, has become endemic also. South Africa is home to a comparatively large number of rabies strains and animal carriers, making it a particularly interesting case study. Environmental changes during the colonial and apartheid periods have helped to explain the increase in rabies cases since the mid-twentieth century. Moreover, developments in the biological and ecological sciences have provided insights into why the rabies virus has become endemic in certain wildlife species.

  3. The Science of Symbiosis and Linguistic Democracy in Early Twentieth-century Japan

    Directory of Open Access Journals (Sweden)

    Sho Konishi

    2015-04-01

    Full Text Available Focusing on the early twentieth-century Japanese Esperantist and popular celebrity writer Miyazawa Kenji as an embodiment of a larger intellectual phenomenon of early twentieth century Japan, the essay delineates the scientific world view behind the Esperanto movement and corresponding internal logic that developed in the language movement's foundational years. It argues that Esperantism in Japan in its early years was not an isolated linguistic movement among a small number of leftist intellectuals, but part of a much larger intellectual, cultural, and social movement that reflected the particular scientific worldview of what I call 'anarchist science'. This worldview defied the conceptual bifurcations of 'modern vs. tradition' and 'nature vs. culture' in modern history. A history of its vision offers a fresh perspective on modern history, future visions of the past, and the historical meanings of Esperantism.

  4. The concept of time in early twentieth-century philosophy a philosophical thematic atlas

    CERN Document Server

    2016-01-01

    This book presents a collection of authoritative contributions on the concept of time in early twentieth-century philosophy. It is structured in the form of a thematic atlas: each section is accompanied by relevant elementary logic maps that reproduce in a “spatial” form the directionalities (arguments and/or discourses) reported on in the text. The book is divided into three main sections, the first of which covers phenomenology and the perception of time by analyzing the works of Bergson, Husserl, Sartre, Merleau-Ponty, Deleuze, Guattari and Derrida. The second section focuses on the language and conceptualization of time, examining the works of Cassirer, Wittgenstein, Heidegger, Lacan, Ricoeur and Foucault, while the last section addresses the science and logic of time as they appear in the works of Guillaume, Einstein, Reichenbach, Prigogine and Barbour. The purpose of the book is threefold: to provide readers with a comprehensive overview of the concept of time in early twentieth-century philosophy; ...

  5. The biological universe. The twentieth century extraterrestrial life debate and the limits of science.

    Science.gov (United States)

    Dick, S. J.

    Throughout the twentieth century, from the furor over Percival Lowell's claim of canals on Mars to the sophisticated Search for Extraterrestrial Intelligence, otherworldly life has often intrigued and occasionally consumed science and the public. Does 'biological law' reign throughout the universe? Are there other histories, religions, and philosophies outside of those on Earth? Do extraterrestrial minds ponder the mysteries of the universe? The attempts to answer these often asked questions form one of the most interesting chapters in the history of science and culture, and this is the first book to provide a rich and colorful history of those attempts during the twentieth century. Covering a broad range of topics, including the search for life in the solar system, the origins of life, UFOs, and aliens in science fiction, the author shows how the concept of extraterrestrial intelligence is a world view of its own, a 'biophysical cosmology' that seeks confirmation no less than physical views of the universe.

  6. The biological universe: the twentieth-century extraterrestrial life debate and the limits of science

    Science.gov (United States)

    Dick, Steven J.

    Throughout the twentieth century, from the furor over Percival Lowell's claim of canals on Mars to the sophisticated Search for Extraterrestrial Intelligence, otherworldly life has often intrigued and occasionally consumed science and the public. Does `biological law' reign throughout the universe? Are there other histories, religions, and philosophies outside of those on Earth? Do extraterrestrial minds ponder the mysteries of the universe? The attempts toanswer these often asked questions form one of the most interesting chapters in the history of science and culture, and The Biological Universe is the first book to provide a rich and colorful history of those attempts during the twentieth century. Covering a broad range of topics, including the search for life in the solar system, the origins of life, UFOs, and aliens in science fiction, Steven J. Dick shows how the concept of extraterrestrial intelligence is a world view of its own, a `biophysical cosmology' that seeks confirmation no less than physical views of the universe.

  7. An introduction to the poetics of sacred sound in twentieth-century music

    OpenAIRE

    Luigi Antonio Irlandini

    2013-01-01

    Along the twentieth century has occurred the beginning of a fusion between two very different horizons: Western musical composition and Hindu sonic theology. The essential content of this theology and the changes in Western musical language and aesthetics, society and culture which have allowed this fusion to take place are briefly outlined. Instrumental and vocal works by Karlheinz Stockhausen, Giacinto Scelsi, Michael Vetter and David Hykes provide specific examples and, in particular, rais...

  8. The twentieth century was the wettest period in northern Pakistan over the past millennium

    OpenAIRE

    Treydte, K. S.; G. H. Schleser; Gerhard Helle; D. C. Frank; M. Winiger; Haug,G.H.; Esper, J.

    2006-01-01

    Twentieth-century warming could lead to increases in the moisture-holding capacity of the atmosphere, altering the hydrological cycle and the characteristics of precipitation. Such changes in the global rate and distribution of precipitation may have a greater direct effect on human well-being and ecosystem dynamics than changes in temperature itself. Despite the co-variability of both of these climate variables, attention in long-term climate reconstruction has mainly concentrated on tempera...

  9. American Influence on Chinese Physics Study in the Early Twentieth Century

    Science.gov (United States)

    Hu, Danian

    2016-01-01

    To save China from the perils she faced in the early twentieth century, the majority of the Chinese seemed to agree that it was necessary to strengthen the country by developing shiye or industry and commerce. For this purpose, they overhauled China's education system and sent a large number of students to study overseas. Many of them enrolled in American colleges, sponsored either by governmental grants or by private funds. As American physics advanced rapidly during the early twentieth century, Chinese physicists studying in top US institutions received first-class professional training. They later went on to become a main driving force in Chinese physics development. The study-in-America programs were apparently more successful than other study-overseas programs. Among other factors, the historical lessons learned from the aborted Chinese Educational Mission in the 1870s, the prevalent and long-time presence of American mission schools in China, and stable public and private funding contributed to their success. American-trained Chinese physicists not only advanced physics study in China but also played leading roles in the development of Chinese science and technology during the twentieth century. This fertile and far-reaching American influence has been embedded in all their accomplishments.

  10. Races at War: Nationalism and Genocide in Twentieth Century Europe

    Science.gov (United States)

    2005-03-01

    the Serbs, like the Nazis, still made the price of leaving very high. In one example, in the city of Banja Luka , Bosnian Muslims who wanted to...Diana Paul, a human rights worker in Banja Luka . 122 Naimark, p. 163. 59 namely to drive off non-Serb populations in order to create homogeneous Serb...locations. In Banja Luka , the Serbs destroyed 200 mosques out of 202 in 1993. Even non-Serb cemeteries were “routinely

  11. Forced changes to twentieth century ENSO diversity in a last Millennium context

    Science.gov (United States)

    Stevenson, Samantha; Capotondi, Antonietta; Fasullo, John; Otto-Bliesner, Bette

    2017-03-01

    The El Niño/Southern Oscillation (ENSO) exhibits considerable differences between the evolution of individual El Niño and La Niña events (`ENSO diversity'), with significant implications for impacts studies. However, the degree to which external forcing may affect ENSO diversity is not well understood, due to both internal variability and potentially compensatory contributions from multiple forcings. The Community Earth System Model Last Millennium Ensemble (CESM LME) provides an ideal testbed for studying the sensitivity of twentieth century ENSO to forced climate changes, as it contains many realizations of the 850-2005 period with differing combinations of forcings. Metrics of ENSO amplitude and diversity are compared across LME simulations, and although forced changes to ENSO amplitude are generally small, forced changes to diversity are often detectable. Anthropogenic changes to greenhouse gas and ozone/aerosol emissions modify the persistence of Eastern and Central Pacific El Niño events, through shifts in the upwelling and zonal advective feedbacks; these influences generally cancel one another over the twentieth century. Other forcings can also be quite important: land use changes amplify Eastern Pacific El Niño events via modulating zonal advective heating, and orbital forcing tends to preferentially terminate twentieth century Central Pacific El Niño events due to enhanced eastern Pacific cooling during boreal winter and spring. Our results indicate that multiple anthropogenic and natural forcings can have substantial impacts on ENSO diversity, and suggest that correctly representing the net ENSO diversity response to climate change will depend on the precise balance between all these influences.

  12. In Referees We Trust? Controversies over Grant Peer Review in the Late Twentieth Century

    Science.gov (United States)

    Baldwin, Melinda

    While many accounts of external refereeing assume that it has been a consistent part of science since the seventeenth century, the practice developed far more slowly and haphazardly than many observers realize, and it was not until after the Second World War that ''peer review'' became considered an essential part of scientific publishing or grant-making. This talk will explore refereeing procedures at American grant-giving organizations in the twentieth century, focusing especially on the National Science Foundation and the National Institutes of Health. The creators of the NSF and the NIH put refereeing systems in place at their foundation. However, the form and function of these systems differed from modern ''peer review'' in several important ways. At the NSF the initial purpose of the referee process was to advise the NSF program directors, not to dictate funding decisions. At the NIH, small ''study sections'' devoted to particular subjects made recommendations to the NIH leadership, which rendered final judgments. However, beginning in the 1960s a series of controversies about NIH and NSF grants placed refereeing procedures at these organizations under more intense scrutiny. These debates culminated in six days of Special Oversight Hearings into the NSF's peer review process in the summer of 1975. Following the hearings, both the NSF and NIH reformed their review processes to place more emphasis on referees' opinions about grant proposals, making peer review increasingly responsible for decision-making. These controversies illustrate that refereeing continued to undergo significant changes in form and purpose throughout the twentieth century, and further suggest that both the scientific community and the public placed increased emphasis on the role of the referee during the late twentieth century.

  13. Ocean heat content variability in an ensemble of twentieth century ocean reanalyses

    Science.gov (United States)

    de Boisséson, Eric; Balmaseda, Magdalena Alonso; Mayer, Michael

    2017-08-01

    This paper presents a ten-member ensemble of twentieth century Ocean ReAnalyses called ORA-20C. ORA-20C assimilates temperature and salinity profiles and is forced by the ECMWF twentieth century atmospheric reanalysis (ERA-20C) over the 1900-2010 period. This study attempts to identify robust signals of ocean heat content change in ORA-20C and detect contamination by model errors, initial condition uncertainty, surface fluxes and observing system changes. It is shown that ORA-20C trends and variability in the first part of the century result from the surface fluxes and model drift towards a warmer mean state and weak meridional overturning circulation. The impact of the observing system in correcting the mean state causes the deceleration of the warming trend and alters the long-term climate signal. The ensemble spread reflects the long-lasting memory of the initial conditions and the convergence of the system to a solution compatible with surface fluxes, the ocean model and observational constraints. Observations constrain the ocean heat uptake trend in the last decades of the twentieth century, which is similar to trend estimations from the post-satellite era. An ocean heat budget analysis attributes ORA-20C heat content changes to surface fluxes in the first part of the century. The heat flux variability reflects spurious signals stemming from ERA-20C surface fields, which in return result from changes in the atmospheric observing system. The influence of the temperature assimilation increments on the heat budget is growing with time. Increments control the most recent ocean heat uptake signals, highlighting imbalances in forced reanalysis systems in the ocean as well as in the atmosphere.

  14. The Diasporic Dimensions of British Caribbean Federation in the Early Twentieth Century

    Directory of Open Access Journals (Sweden)

    Eric D. Duke

    2009-12-01

    Full Text Available [Second and third pragraph] While much has been written on the significance of British Caribbean activists in various movements associated with black diaspora politics in the twentieth century, particularly their important roles in Pan-African struggles, little has been written on how the various British Caribbean colonies themselves were envisioned among diaspora activists and within the scope of black diaspora politics. Did such Caribbean activists, especially those interested in and connected to diasporic movements beyond the British Caribbean, and their African American and African counterparts forsake the British West Indies as a focus of political engagement for other lands and causes? If not, what was the place of “West Indian liberation” and nation building in the British Caribbean in relation to black diasporic struggles in the early twentieth century? This article address these questions through an examination of how the idea of a united “West Indian nation” (via a federation or closer union among British Caribbean colonies was envisioned within black diaspora politics from the turn of the twentieth century through the 1920s, and the ways in which racial consciousness and motivations informed conceptualizations of such a nation among black political activists of the British Caribbean and other parts of the diaspora. This study argues that efforts to create a federation in the Anglophone Caribbean were much more than simply imperial or regional nation-building projects. Instead, federation was also a diasporic, black nation-building endeavor intricately connected to notions of racial unity, racial uplift, and black self-determination.

  15. Jane Dawson & Alice Entwistle. A History of Twentieth-Century British Women’s Poetry

    Directory of Open Access Journals (Sweden)

    Rainer EMIG

    2007-06-01

    Full Text Available A gigantic task well executed, this is what Dowson and Entwistle’s book turns out to be. It takes the bull (or should it be the cow, the mad cow of Jo Shapcott’s amusing poems? by the horns and tries to come up with a possible history of the many diverse and often uncollected female voices in Britain in the twentieth century. Dowson and Entwistle’s definition of “British Women’s Poetry” is flexible: “The following poets are British born, published in Britain and/or judged to have made a sign...

  16. Pain: metaphor, body, and culture in Anglo-American societies between the eighteenth and twentieth centuries.

    Science.gov (United States)

    Bourke, Joanna

    2014-10-02

    This article explores the relationship between metaphorical languages, body, and culture, and suggests that such an analysis can reveal a great deal about the meaning and experience of pain in Anglo-American societies between the eighteenth and twentieth centuries. It uses concepts within embodied cognition to speculate on how historians can write a history of sensation. Bodies are actively engaged in the linguistic processes and social interactions that constitute painful sensations. Language is engaged in a dialogue with physiological bodies and social environments. And culture collaborates in the creation of physiological bodies and metaphorical systems.

  17. Mid-Twentieth Century Modern Dance in the Twenty-first Century

    OpenAIRE

    Puleio, Dante

    2017-01-01

    Mid-Twentieth Century Modern Dance in the Twenty-First CenturyThe relevance of modern dance being performed today has been a growing topic in the dance field as legacy companies age and the field of contemporary dance continues to expand. This thesis begins with critical response to mid-century modern dance in the work of well-known dance critics John Martin, Edwin Denby and Louis Horst and how they substantiated modern dance’s place in dance history. My interviews with dance critics Alastair...

  18. Pain, sympathy and the medical encounter between the mid eighteenth and the mid twentieth centuries.

    Science.gov (United States)

    Bourke, Joanna

    2012-08-01

    Witnessing people in pain inevitably elicits anxiety in physicians and other caregivers. Physicians are often required to inflict certain types of discomforts in order to alleviate other, more destructive, pains. Accusations that physicians lacked sympathy can be heard throughout the centuries. This article explores the diverse medical responses to such claims between the eighteenth and twentieth centuries. It interrogates changing definitions of clinical sympathy. The concept of sympathy was continually being reworked for each generation of medical professional. Crucially, in this reworking, philosophers (such as Adam Smith) and physicians came into dialogue. Cultures of sympathy were understood in both physiological and metaphorical terms, and were tied to changing notions of professionalization.

  19. [The transparent body: medical imaging and popular culture in the twentieth century].

    Science.gov (United States)

    Ortega, Francisco

    2006-10-01

    In today's societies, successful new medical imaging technologies have focused unprecedented attention on the inside of the human body. These techniques have jumped the walls of the biomedical field per se, penetrating the fields of culture and law. The article traces a genealogy of twentieth-century medical techniques used to visualize the human body and brain, from X-rays to the more sophisticated CTs, MRIs, and PET scans. It explores the changes that these ever more numerous visualization techniques have occasioned in our corporality and examines how these technologies have been received in the courtroom and in popular culture, especially in literature, movies, and magazines.

  20. Body architects in Physical Education and Sports. Among files, skills and knowledge (Argentina early twentieth century

    Directory of Open Access Journals (Sweden)

    Pablo Ariel Scharagrodsky

    2015-09-01

    Full Text Available The following article discusses the creation of two 'skills' with knowledge, procedures, techniques and specific competence when it comes to educate moving bodies: Physical Education teachers and sports doctors in Argentina during the first half of the twentieth century. Starting from the social history of the body (Turner, 1989; Porter, 2003; Vigarello, 2005, this paper focuses its view on knowledge (anthropometry, biometrics and biotypology and procedures (physical bulletins and sports biotypological files used by both 'skills' to identify the ideal types of built corporeality such as the omissions, exclusions and silences that accompanied those body ideals when placing them in their gymnastic, recreational and / or sports 'right place'

  1. Genesis of home care in Brazil at the start of the twentieth century.

    Science.gov (United States)

    Oliveira, Stefanie Griebeler; Kruse, Maria Henriqueta Luce

    2016-06-01

    Objective to discuss the conditions that enabled home care at the beginning of the twentieth century. Method study of the genealogic inspiration on home care. The empirical material consisted of legal documents on the subject that were published in the Official Journal. The documents were studied using analytical tools, such as Power, Discipline and Biopolitics, which were inspired in Foucault. Results two analytical categories were established, "home inspection: visiting nurses and tuberculosis" and "records: political and economic apparatus". Final considerations tuberculosis, the new profession of visiting nurses, inspection records and the detailed analysis of the cities grant home care a nature of surveillance, inspection and control to conduct the behaviour of individuals.

  2. Pain: metaphor, body, and culture in Anglo-American societies between the eighteenth and twentieth centuries

    Science.gov (United States)

    Bourke, Joanna

    2014-01-01

    This article explores the relationship between metaphorical languages, body, and culture, and suggests that such an analysis can reveal a great deal about the meaning and experience of pain in Anglo-American societies between the eighteenth and twentieth centuries. It uses concepts within embodied cognition to speculate on how historians can write a history of sensation. Bodies are actively engaged in the linguistic processes and social interactions that constitute painful sensations. Language is engaged in a dialogue with physiological bodies and social environments. And culture collaborates in the creation of physiological bodies and metaphorical systems.

  3. The State of Native America at the End of the Twentieth Century

    Directory of Open Access Journals (Sweden)

    J. Kelly Robison

    2007-05-01

    Full Text Available When stereotypes of modern Native Americans are brought forward, these usually manifest themselves in visions of poor Indians living on reservations, which are on lands no one else wanted. Modern Native Americans are often stereotyped as drunks or succumbing to the pressure of gamblers to open their reservations to casinos. One place to start in order to disprove these stereotypes is the statistical data. What follows is not an interpretive essay in the classic scholarly vein, but an informative one that provides a picture of the state of Native America at the end of the Twentieth Century based on current statistical data.

  4. Alternatives to Dam Building: Deindustrialization and the Redevelopment of Waterways in the Northeast During the Twentieth Century

    Science.gov (United States)

    Taber, J. S.; Pompeii, B. J.; Nicoletti, C.; Lopez-Morales, C. A.

    2010-12-01

    The Northeast United States contains more dams than any other region in the country but it lacks structures on the scale of the Hoover or Bonneville dams in the American West. This work addresses why the Northeast lacks such large dams and how the pattern of small dams within the region shaped its social development. During the twentieth century, changing social and economic conditions rendered the initial purposes of many dams in the region moot, but these structures continued to influence hydrologic conditions and the provision of ecosystem services to an expanding population. The continued existence of many of these dams resulted from a worldview unable to conceive of dam removal as it did to the economic or environmental services provided by the structure. Documenting the process by which society developed alternatives to dam building in this region can contextualize the origins and contingent character of ideas about dam removal. The overarching theme in this process is the deindustrialization of the Northeast, which pitted the interests of industrial cities undergoing economic reorganization, emerging suburban communities, and growing service industries in the region. This paper considers changing attitudes toward dams as part of a four step process: (1) although the mill dams of the industrial revolution remained after electrification rendered manufacturers independent of direct water power in the early twentieth century, deindustrialization reshaped the political and legal responses to flooding by stregnthening the political and economic position of service industries and suburban residential interests; (2) the most tangible response to this development was proposed federal investment in dam building in the region between the 1930s and the 1950s; (3) political conflicts between local interests and federal proposals for dam construction slowed down the dam building process and enabled people to consider alternative strategies for flood control and power

  5. Charles Darwin's reputation: how it changed during the twentieth-century and how it may change again.

    Science.gov (United States)

    Amundson, Ron

    2014-01-01

    Charles Darwin died in 1882. During the twentieth century his reputation varied through time, as the scientific foundation of evolutionary theory changed. Beginning the century as an intellectual hero, he soon became a virtual footnote as experimental approaches to evolution began to develop. As the Modern Synthesis developed his reputation began to rise again until eventually he was identified as a founding father of the Modern Synthesis itself. In the meantime, developmental approaches to evolution began to challenge certain aspects of the Modern Synthesis. Synthesis authors attempted to refute the relevance of development by methodological arguments, some of them indirectly credited to Darwin. By the end of the century, molecular genetics had given new life to development approaches to evolution, now called evo devo. This must be seen as a refutation of the aforesaid methodological arguments of the Modern Synthesis advocates. By the way, we can also see now how the historiography that credited Darwin with the Synthesis was in error. In conclusion, one more historical revision is suggested. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Continuum mechanics through the ages from the renaissance to the twentieth century : from hydraulics to plasticity

    CERN Document Server

    Maugin, Gérard A

    2016-01-01

    Mixing scientific, historic and socio-economic vision, this unique book complements two previously published volumes on the history of continuum mechanics from this distinguished author. In this volume, Gérard A. Maugin looks at the period from the renaissance to the twentieth century and he includes an appraisal of the ever enduring competition between molecular and continuum modelling views. Chapters trace early works in hydraulics and fluid mechanics not covered in the other volumes and the author investigates experimental approaches, essentially before the introduction of a true concept of stress tensor. The treatment of such topics as the viscoelasticity of solids and plasticity, fracture theory, and the role of geometry as a cornerstone of the field, are all explored. Readers will find a kind of socio-historical appraisal of the seminal contributions by our direct masters in the second half of the twentieth century. The analysis of the teaching and research texts by Duhem, Poincaré and Hilbert on cont...

  7. A social theory of language announced at the threshold of the twentieth century by Antoine Meillet

    Directory of Open Access Journals (Sweden)

    Daniel Marra

    2012-12-01

    Full Text Available Ferdinand de Saussure (1857-1913 defined langue as a social fact, a reality which is exterior to the individual and his will, and belongs to the society. He has never quoted Émile Durkheim (1858-1917 while discussing such concept, however the French sociologist’s conception was widely known in the intellectual milieu of the early twentieth century. Moreover, Antoine Meillet (1866-1936, a disciple of Saussure, while contributing to Durkheim’s newspaper, L’année sociologique (1905-1906, at about the same time that Saussure began the CGL (1907-1911 in Geneva, characterized language as a social fact referring to the concept established by Durkheim. This article deals with the linguistic ideas of Meillet that directly or indirectly influenced a large number of linguists for several decades of the twentieth century. The linguist dedicated himself to both the historical and comparative studies of Indo-European languages, as to the social and historical nature of language. The social aspect of his announced theory is the central theme of this historiographical-linguistic study.

  8. The Development of SONAR as a Tool in Marine Biological Research in the Twentieth Century

    Directory of Open Access Journals (Sweden)

    John A. Fornshell

    2013-01-01

    Full Text Available The development of acoustic methods for measuring depths and ranges in the ocean environment began in the second decade of the twentieth century. The two world wars and the “Cold War” produced three eras of rapid technological development in the field of acoustic oceanography. By the mid-1920s, researchers had identified echoes from fish, Gadus morhua, in the traces from their echo sounders. The first tank experiments establishing the basics for detection of fish were performed in 1928. Through the 1930s, the use of SONAR as a means of locating schools of fish was developed. The end of World War II was quickly followed by the advent of using SONAR to track and hunt whales in the Southern Ocean and the marketing of commercial fish finding SONARs for use by commercial fisherman. The “deep scattering layer” composed of invertebrates and fish was discovered in the late 1940s on the echo sounder records. SONARs employing high frequencies, broadband, split beam, and multiple frequencies were developed as methods for the detection, quantification and identification of fish and invertebrates. The study of fish behavior has seen some use of passive acoustic techniques. Advancements in computer technology have been important throughout the last four decades of the twentieth century.

  9. Spas, mineral waters, and hydrological science in twentieth-century France.

    Science.gov (United States)

    Weisz, G

    2001-09-01

    This essay examines the survival of waters therapy in twentieth-century France with a view to understanding the conditions that make a therapy convincing in one national context and not in another. Part of the explanation for this survival has to do with the size and power of the spa industry. Where this industry was strong and economically powerful--as it was in France--its survival became a national priority. Of equal importance, however, was the role of the medical elite. In twentieth-century France, a small but influential group of elite physicians served as the chief architects of the continued survival and development of water cures. The primary mechanism for this process was a massive and successful campaign to introduce hydrology into the curriculum of medical schools. Once this was achieved, a large corps of academic hydrologists were in a position to produce significant amounts of convincing hydrological science that seemed to demonstrate the varied physiological effects of mineral waters. By the 1940s mineral waters had enough scientific visibility to ensure their inclusion without controversy in the national health insurance system that was being set up.

  10. Labs in the field? Rocky mountain biological stations in the early twentieth century.

    Science.gov (United States)

    Vetter, Jeremy

    2012-01-01

    Biological field stations proliferated in the Rocky Mountains region of the western United States during the early decades of the twentieth century. This essay examines these Rocky Mountain field stations as hybrid lab-field sites from the perspective of the field side of the dichotomy: as field sites with raised walls rather than as laboratories whose walls with the natural world have been lowered. Not only were these field stations transformed to be more like laboratories, but they were also embedded within the particular regional environmental and institutional context of the Rocky Mountains. Using the University of Colorado's Mountain Laboratory at Tolland and other contemporaneous sites as examples, this essay analyzes key features of these sites, including their location within transportation networks, buildings, equipment, personnel, scheduling, recreational and social activities, and other material and social practices on the ground. Considering both the distinctive and shared characteristics of the Rocky Mountain field stations in comparison to other types of field stations provides a more complete picture of the diversity and range of lab-field hybrid sites in the biological sciences in the early twentieth-century United States.

  11. Pronounced differences between observed and CMIP5-simulated multidecadal climate variability in the twentieth century

    Science.gov (United States)

    Kravtsov, Sergey

    2017-06-01

    Identification and dynamical attribution of multidecadal climate undulations to either variations in external forcings or to internal sources is one of the most important topics of modern climate science, especially in conjunction with the issue of human-induced global warming. Here we utilize ensembles of twentieth century climate simulations to isolate the forced signal and residual internal variability in a network of observed and modeled climate indices. The observed internal variability so estimated exhibits a pronounced multidecadal mode with a distinctive spatiotemporal signature, which is altogether absent in model simulations. This single mode explains a major fraction of model-data differences over the entire climate index network considered; it may reflect either biases in the models' forced response or models' lack of requisite internal dynamics, or a combination of both.Plain Language SummaryGlobal and regional warming trends over the course of the twentieth century have been nonuniform, with decadal and longer periods of faster or slower warming, or even cooling. Here we show that state-of-the-art global models used to predict climate fail to adequately reproduce such multidecadal climate variations. In particular, the models underestimate the magnitude of the observed variability and misrepresent its spatial pattern. Therefore, our ability to interpret the observed climate change using these models is limited.

  12. Early twentieth century response of the global atmospheric electric circuit to ENSO

    Science.gov (United States)

    Harrison, G.; Joshi, M.

    2012-04-01

    The global atmospheric electric circuit links charge separation in disturbed weather regions with current flow in the fair weather regions elsewhere. Variations in disturbed weather, such as the changes in lightning associated with Pacific ocean temperature anomalies, can be expected in turn to modify currents flowing in the global atmospheric electric circuit. Strengthening and weakening of the global circuit current has been observed* to follow El Niño and La Niña respectively, from northern hemisphere atmospheric electricity data obtained during the 1970s. Extending this relationship quantitatively into the first half of the twentieth century is pursued here, using surface data from multiple atmospheric electricity observatories including measurements from the southern hemisphere. The independent atmospheric electricity time series from the observatories show similar variations, which is a pre-requisite for inferring global circuit variations from surface measurement. Combining the measurements allows the global circuit sensitivity to ENSO sea surface temperature anomalies to be derived during the earlier part of the twentieth century. * R.G. Harrison, M. Joshi, K. Pascoe, Inferring convective responses to El Niño with atmospheric electricity measurements at Shetland Environ Res Lett 6 (2011) 044028 http://iopscience.iop.org/1748-9326/6/4/044028/

  13. Real Men Wear Uniforms: Photomontage, Postcards, and Military Visual Culture in Early Twentieth-Century Germany

    Directory of Open Access Journals (Sweden)

    Elizabeth Otto

    2012-04-01

    Full Text Available This essay examines early twentieth-century German representations of men and women in uniform to consider how mass culture allowed individuals to participate in aspects of gender construction. It also reveals how masculinity was increasingly linked to military ideals. The pictures under scrutiny here were made in two significant but as yet under-researched types of pictures: pre-avant-garde photomontaged soldier portraits and popular postcards. Both of these visual forms originated in the 1870s, the decade that Germany was itself founded, and they both were in wide circulation by the early twentieth century. Individualized soldier portraits and postcards offered a glorious vision of a man’s military service, and they performed what Theodor Lessing has called Vergemütlichung, the rendering harmless of history. These idealized images of soldierly life were available to a broad swath of the public, but their democratization only extended so far. Representations of women in uniform served to reinforce—through stereotyping and humor—the unquestionably male nature of military institutions and, by extension, of public space. At the same time, by making apparent their own constructed nature, these portraits and postcards offered viewers a glimpse behind the masquerade of masculinity. This essay thus also identifies these images’ links to the subsequent work of avant-garde artists and to the National Socialists’ return to the ideal of uniformed masculinity.

  14. Pioneers of Gentrification: Transformation in Global Neighborhoods in Urban America in the Late Twentieth Century.

    Science.gov (United States)

    Hwang, Jackelyn

    2016-02-01

    Few studies have considered the role of immigration in the rise of gentrification in the late twentieth century. Analysis of U.S. Census and American Community Survey data over 24 years and field surveys of gentrification in low-income neighborhoods across 23 U.S. cities reveal that most gentrifying neighborhoods were "global" in the 1970s or became so over time. An early presence of Asians was positively associated with gentrification; and an early presence of Hispanics was positively associated with gentrification in neighborhoods with substantial shares of blacks and negatively associated with gentrification in cities with high Hispanic growth, where ethnic enclaves were more likely to form. Low-income, predominantly black neighborhoods and neighborhoods that became Asian and Hispanic destinations remained ungentrified despite the growth of gentrification during the late twentieth century. The findings suggest that the rise of immigration after 1965 brought pioneers to many low-income central-city neighborhoods, spurring gentrification in some neighborhoods and forming ethnic enclaves in others.

  15. Surviving the Lunacy Act of 1890: English Psychiatrists and Professional Development during the Early Twentieth Century.

    Science.gov (United States)

    Takabayashi, Akinobu

    2017-04-01

    In recent decades, historians of English psychiatry have shifted their major concerns away from asylums and psychiatrists in the nineteenth century. This is also seen in the studies of twentieth-century psychiatry where historians have debated the rise of psychology, eugenics and community care. This shift in interest, however, does not indicate that English psychiatrists became passive and unimportant actors in the last century. In fact, they promoted Lunacy Law reform for a less asylum-dependent mode of psychiatry, with a strong emphasis on professional development. This paper illustrates the historical dynamics around the professional development of English psychiatry by employing Andrew Abbott's concept of professional development. Abbott redefines professional development as arising from both abstraction of professional knowledge and competition regarding professional jurisdiction. A profession, he suggests, develops through continuous re-formation of its occupational structure, mode of practice and political language in competing with other professional and non-professional forces. In early twentieth-century England, psychiatrists promoted professional development by framing political discourse, conducting a daily trade and promoting new legislation to defend their professional jurisdiction. This professional development story began with the Lunacy Act of 1890, which caused a professional crisis in psychiatry and led to inter-professional competition with non-psychiatric medical service providers. To this end, psychiatrists devised a new political rhetoric, 'early treatment of mental disorder', in their professional interests and succeeded in enacting the Mental Treatment Act of 1930, which re-instated psychiatrists as masters of English psychiatry.

  16. The twentieth century was the wettest period in northern Pakistan over the past millennium

    Science.gov (United States)

    Treydte, Kerstin S.; Schleser, Gerhard H.; Helle, Gerhard; Frank, David C.; Winiger, Matthias; Haug, Gerald H.; Esper, Jan

    2006-04-01

    Twentieth-century warming could lead to increases in the moisture-holding capacity of the atmosphere, altering the hydrological cycle and the characteristics of precipitation. Such changes in the global rate and distribution of precipitation may have a greater direct effect on human well-being and ecosystem dynamics than changes in temperature itself. Despite the co-variability of both of these climate variables, attention in long-term climate reconstruction has mainly concentrated on temperature changes. Here we present an annually resolved oxygen isotope record from tree-rings, providing a millennial-scale reconstruction of precipitation variability in the high mountains of northern Pakistan. The climatic signal originates mainly from winter precipitation, and is robust over ecologically different sites. Centennial-scale variations reveal dry conditions at the beginning of the past millennium and through the eighteenth and early nineteenth centuries, with precipitation increasing during the late nineteenth and the twentieth centuries to yield the wettest conditions of the past 1,000 years. Comparison with other long-term precipitation reconstructions indicates a large-scale intensification of the hydrological cycle coincident with the onset of industrialization and global warming, and the unprecedented amplitude argues for a human role.

  17. Prof C. N. Yang (Physics Nobel Prize 1957) from Tsinghua University (Beijing) during his CERN Colloquium: "Thematic Melodies of Twentieth Century Theoretical Physics: Quantization, Symmetry and Phase Factor".

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Prof C. N. Yang (Physics Nobel Prize 1957) from Tsinghua University (Beijing) during his CERN Colloquium: "Thematic Melodies of Twentieth Century Theoretical Physics: Quantization, Symmetry and Phase Factor".

  18. Tree-ring stable isotopes reveal twentieth-century increases in water-use efficiency of Fagus sylvatica and Nothofagus spp. in Italian and Chilean mountains.

    Directory of Open Access Journals (Sweden)

    Roberto Tognetti

    Full Text Available Changes in intrinsic water use efficiency (iWUE were investigated in Fagus sylvatica and Nothofagus spp. over the last century. We combined dendrochronological methods with dual-isotope analysis to investigate whether atmospheric changes enhanced iWUE of Fagus and Nothofagus and tree growth (basal area increment, BAI along latitudinal gradients in Italy and Chile. Post-maturation phases of the trees presented different patterns in δ13C, Δ13C, δ18O, Ci (internal CO2 concentration, iWUE, and BAI. A continuous enhancement in isotope-derived iWUE was observed throughout the twentieth century, which was common to all sites and related to changes in Ca (ambient CO2 concentration and secondarily to increases in temperature. In contrast to other studies, we observed a general increasing trend of BAI, with the exception of F. sylvatica in Aspromonte. Both iWUE and BAI were uncoupled with the estimated drought index, which is in agreement with the absence of enduring decline in tree growth. In general, δ13C and δ18O showed a weak relationship, suggesting the major influence of photosynthetic rate on Ci and δ13C, and the minor contribution of the regulation of stomatal conductance to iWUE. The substantial warming observed during the twentieth century did not result in a clear pattern of increased drought stress along these latitudinal transects, because of the variability in temporal trends of precipitation and in specific responses of populations.

  19. Tree-ring stable isotopes reveal twentieth-century increases in water-use efficiency of Fagus sylvatica and Nothofagus spp. in Italian and Chilean mountains.

    Science.gov (United States)

    Tognetti, Roberto; Lombardi, Fabio; Lasserre, Bruno; Cherubini, Paolo; Marchetti, Marco

    2014-01-01

    Changes in intrinsic water use efficiency (iWUE) were investigated in Fagus sylvatica and Nothofagus spp. over the last century. We combined dendrochronological methods with dual-isotope analysis to investigate whether atmospheric changes enhanced iWUE of Fagus and Nothofagus and tree growth (basal area increment, BAI) along latitudinal gradients in Italy and Chile. Post-maturation phases of the trees presented different patterns in δ13C, Δ13C, δ18O, Ci (internal CO2 concentration), iWUE, and BAI. A continuous enhancement in isotope-derived iWUE was observed throughout the twentieth century, which was common to all sites and related to changes in Ca (ambient CO2 concentration) and secondarily to increases in temperature. In contrast to other studies, we observed a general increasing trend of BAI, with the exception of F. sylvatica in Aspromonte. Both iWUE and BAI were uncoupled with the estimated drought index, which is in agreement with the absence of enduring decline in tree growth. In general, δ13C and δ18O showed a weak relationship, suggesting the major influence of photosynthetic rate on Ci and δ13C, and the minor contribution of the regulation of stomatal conductance to iWUE. The substantial warming observed during the twentieth century did not result in a clear pattern of increased drought stress along these latitudinal transects, because of the variability in temporal trends of precipitation and in specific responses of populations.

  20. Tree-Ring Stable Isotopes Reveal Twentieth-Century Increases in Water-Use Efficiency of Fagus sylvatica and Nothofagus spp. in Italian and Chilean Mountains

    Science.gov (United States)

    Tognetti, Roberto; Lombardi, Fabio; Lasserre, Bruno; Cherubini, Paolo; Marchetti, Marco

    2014-01-01

    Changes in intrinsic water use efficiency (iWUE) were investigated in Fagus sylvatica and Nothofagus spp. over the last century. We combined dendrochronological methods with dual-isotope analysis to investigate whether atmospheric changes enhanced iWUE of Fagus and Nothofagus and tree growth (basal area increment, BAI) along latitudinal gradients in Italy and Chile. Post-maturation phases of the trees presented different patterns in δ13C, Δ13C, δ18O, Ci (internal CO2 concentration), iWUE, and BAI. A continuous enhancement in isotope-derived iWUE was observed throughout the twentieth century, which was common to all sites and related to changes in Ca (ambient CO2 concentration) and secondarily to increases in temperature. In contrast to other studies, we observed a general increasing trend of BAI, with the exception of F. sylvatica in Aspromonte. Both iWUE and BAI were uncoupled with the estimated drought index, which is in agreement with the absence of enduring decline in tree growth. In general, δ13C and δ18O showed a weak relationship, suggesting the major influence of photosynthetic rate on Ci and δ13C, and the minor contribution of the regulation of stomatal conductance to iWUE. The substantial warming observed during the twentieth century did not result in a clear pattern of increased drought stress along these latitudinal transects, because of the variability in temporal trends of precipitation and in specific responses of populations. PMID:25398040

  1. Duplessis, rachel blau. Writing beyond the ending: narrative strategies of twentieth - century women writers. bloomington: indiana university press, 1985. Duplessis, rachel blau. Writing beyond the ending: narrative strategies of twentieth - century women writers. bloomington: indiana university press, 1985.

    Directory of Open Access Journals (Sweden)

    Susana Bornéo Funck

    2008-04-01

    Full Text Available Describing her study as "a culturally necessary production of possible meanings," Rachel Blau DuPlessis undertakes a oitical interpretation of twentieth-century women writers in terms of their attempts to "delegitimize the cultural conventions established by a sex-gender system and its values." Describing her study as "a culturally necessary production of possible meanings," Rachel Blau DuPlessis undertakes a oitical interpretation of twentieth-century women writers in terms of their attempts to "delegitimize the cultural conventions established by a sex-gender system and its values."

  2. [Hygiene and urban health as seen by physicians, architects and planners during the first half of the twentieth century].

    Science.gov (United States)

    Ibarra, Macarena

    2016-01-01

    Physicians took part in the promotion of public policies that regulated urban and architectural work, before engineers, architects, planners, and even before the State had a chance to take part in the formulation of such policies. Starting in the late nineteenth century, and especially during the first decade of the twentieth century, the State began to lead on the issue of hygiene and public health. This paper focuses on the role of these professionals, who generated debates within their respective disciplines, or provided -as ministries, public servants or consultants- technical knowledge to the central government. These debates are still relevant for two reasons. First, they serve as reminders of the way in which the voice of these professionals was crucial not only within their respective disciplines, but also in order to place the issue of hygiene and public health on the agenda and to promote public policies related to the urban environment and its population. Secondly, these debates represent a challenge to current planners, as this historic context provides insight on the complex relationship between public health and planning, which hitherto has received little attention.

  3. ‘Canonization in early twentieth-century Chinese art history’

    Directory of Open Access Journals (Sweden)

    Guo Hui

    2014-06-01

    Full Text Available Since the 1980s, the discussion of canons has been a dominant theme in the discipline of Western art history. Various concerns have emerged regarding ‘questions of artistic judgment’, ‘the history genesis of masterpieces’, ‘variations in taste’, ‘the social instruments of canonicity’, and ‘how canons disappear’. Western art historians have considered how the canon’s appearance in Western visual art embodies aesthetic, ideological, cultural, social, and symbolic values. In Chinese art history, the idea of a canon including masterpieces, important artists, and forms of art, dates back to the mid ninth century when Zhang Yanyuan wrote his painting history Record of Famous Painters of All the Dynasties. Faced with quite different political, economic, and social conditions amid the instability of the early twentieth century, Chinese scholars attempted to discover new canons for cultural orthodoxy and authority. Modern means for canonization, such as museums and exhibition displays, cultural and academic institutions, and massive art publications with image reproduction in good quality, brought the process up to an unprecedented speed. It is true that most of these means have comparable counterparts in pre-modern times. However, their enormous scope and overwhelming influence are far beyond the reach of their imperial counterparts. Through an inter-textual reading of the publications on Chinese art history in early twentieth-century China, this paper explores the transformation of canons in order to shed light on why and how canonical formation happened during the Republican period of China. Despite the diverse styles and strategies which Chinese writers used in their narratives, Chinese art historical books produced during the Republican period canonized and de-canonized artworks. In this paper, the discussion of these texts, with reference to other art historical works, comprises three parts: 1 canon formation of artistic forms

  4. Did the 1918 influenza cause the twentieth century cardiovascular mortality epidemic in the United States?

    Directory of Open Access Journals (Sweden)

    Steven Tate

    2016-10-01

    Full Text Available During most of the twentieth century, cardiovascular mortality increased in the United States while other causes of death declined. By 1958, the age-standardized death rate (ASDR for cardiovascular causes for females was 1.84 times that for all other causes, combined (and, for males, 1.79×. Although contemporary observers believed that cardiovascular mortality would remain high, the late 1950s and early 1960s turned out to be the peak of a roughly 70-year epidemic. By 1988 for females (1986 for males, a spectacular decline had occurred, wherein the ASDR for cardiovascular causes was less than that for other causes combined. We discuss this phenomenon from a demographic point of view. We also test a hypothesis from the literature, that the 1918 influenza pandemic caused the cardiovascular mortality epidemic; we fail to find support.

  5. Market Research and Socio-Political Consciousness in the Twentieth Century

    DEFF Research Database (Denmark)

    Schwarzkopf, Stefan

    2013-01-01

    Purpose – This paper investigates the case of the eminent British market researcher and social scientist Mark Alexander Abrams (1906 – 1994). Abrams’ career as a researcher spanned the six decades between the late 1920s and the late 1980s, and it bridged the gap between commercial market...... and consumer research on the one side and governmental social research on the other. By focusing on Abrams’ research strategies and career moves over these six decades, the paper establishes an alternative historical narrative to those that privilege the impact of capitalist market structures on the making...... of marketing as a professional field and academic discipline in the twentieth century. Design/methodology/approach – Based on archival research, the paper firstly establishes the biographical details of Abrams’ life and work. Secondly, the paper uses methodological and theoretical tools of historical sociology...

  6. Taming the unknown a history of algebra from antiquity to the early twentieth century

    CERN Document Server

    Katz, Victor J

    2014-01-01

    What is algebra? For some, it is an abstract language of x's and y's. For mathematics majors and professional mathematicians, it is a world of axiomatically defined constructs like groups, rings, and fields. Taming the Unknown considers how these two seemingly different types of algebra evolved and how they relate. Victor Katz and Karen Parshall explore the history of algebra, from its roots in the ancient civilizations of Egypt, Mesopotamia, Greece, China, and India, through its development in the medieval Islamic world and medieval and early modern Europe, to its modern form in the early twentieth century. Defining algebra originally as a collection of techniques for determining unknowns, the authors trace the development of these techniques from geometric beginnings in ancient Egypt and Mesopotamia and classical Greece. They show how similar problems were tackled in Alexandrian Greece, in China, and in India, then look at how medieval Islamic scholars shifted to an algorithmic stage, which was further dev...

  7. Body and Psychiatric Discourse in the Early Twentieth Century in Uruguay: Insufficiency, Weakness and Adaptation

    Directory of Open Access Journals (Sweden)

    Agustina Craviotto Corbellini

    2016-08-01

    Full Text Available This study analyzes the psychiatric medical discourse and experimental psychology during the twentieth century in Uruguay, as expert knowledge on children and as referents of the pedagogic discourse of that period. As an introduction some key elements of psychiatry in the country are presented; from them, it is stuyed how the dysfunction of the body became the focus of analysis that led to a series of school children´s classifications. The relationship of the dysfunctional body with school learning is at the core of the reflection, and indiscipline and mental weaknesses are taken as elements articulating the psychiatric and psychological discourses with the pedagogical one, through the notion of adjustment disorder.

  8. Natural histories of infectious disease: ecological vision in twentieth-century biomedical science.

    Science.gov (United States)

    Anderson, Warwick

    2004-01-01

    During the twentieth century, disease ecology emerged as a distinct disciplinary network within infectious diseases research. The key figures were Theobald Smith, F. Macfarlane Burnet, René Dubos, and Frank Fenner. They all drew on Darwinian evolutionism to fashion an integrative (but rarely holistic) understanding of disease processes, distinguishing themselves from reductionist "chemists" and mere "microbe hunters." They sought a more complex, biologically informed epidemiology. Their emphasis on competition and mutualism in the animated environment differed from the physical determinism that prevailed in much medical geography and environmental health research. Disease ecology derived in part from studies of the interaction of organisms - micro and macro - in tropical medicine, veterinary pathology, and immunology. It developed in postcolonial settler societies. Once a minority interest, disease ecology has attracted more attention since the 1980s for its explanations of disease emergence, antibiotic resistance, bioterrorism, and the health impacts of climate change.

  9. Medical confidentiality in the late nineteenth and early twentieth centuries: an Anglo-German comparison1

    Science.gov (United States)

    2012-01-01

    Summary Professional secrecy of doctors became an issue of considerable medico-legal and political debate in the late nineteenth and early twentieth centuries in both Germany and England, although the legal preconditions for this debate were quite different in the two countries. While in Germany medical confidentiality was a legal obligation and granted in court, no such statutory recognition of doctors’ professional secrecy existed in England. This paper is a comparative analysis of medical secrecy in three key areas - divorce trials, venereal disease and abortion - in both countries. Based on sources from the period between c.1870 and 1939, our paper shows how doctors tried to define the scope of professional secrecy as an integral part of their professional honour in relation to important matters of public health. PMID:21077462

  10. Physiology, propaganda, and pound animals: medical research and animal welfare in mid-twentieth century America.

    Science.gov (United States)

    Parascandola, John

    2007-07-01

    In 1952, the University of Michigan physiologist Robert Gesell shocked his colleagues at the business meeting of the American Physiological Society by reading a prepared statement in which he claimed that some of the animal experimentation being carried out by scientists was inhumane. He especially attacked the National Society for Medical Research (NSMR), an organization that had been founded to defend animal experimentation. This incident was part of a broader struggle taking place at the time between scientists and animal welfare advocates with respect to what restrictions, if any, should be placed on animal research. A particularly controversial issue was whether or not pound animals should be made available to laboratories for research. Two of the prominent players in this controversy were the NSMR and the Animal Welfare Institute, founded and run by Gesell's daughter, Christine Stevens. This article focuses on the interaction between these two organizations within the broader context of the debate over animal experimentation in the mid-twentieth century.

  11. [Puppet shows, Mexican television and health education in the mid-twentieth century].

    Science.gov (United States)

    Gudiño, María Rosa; Sosenski, Susana

    2016-10-10

    This article resurrects the puppet show Las calenturas de Don Ferruco (Don Ferruco's Fevers), which was televised in the late 1950s in order to help eradicate malaria in Mexico, as a useful instrument for health education. It analyzes how the spread of educational puppet shows on Mexican television showed the need to keep updating preventive healthcare pedagogy and it underlines the importance of television as an educational health-promotion production in the mid-twentieth century. The article discusses the early use of puppet shows as an especially important tool for what would later become mass-media transmission of discourses from the Secretaría de Salubridad y Asistencia (Department of Health and Healthcare).

  12. The Lost Worlds of Messmore & Damon: Science, Spectacle & Prehistoric Monsters in early-twentieth century America.

    Science.gov (United States)

    Manias, Chris

    2016-09-01

    In 1924, the model-making company Messmore & Damon, Inc. of New York unleashed their masterpiece: the Amphibious Dinosaurus Brontosaurus, a moving, breathing, roaring animatronic dinosaur, based on displays in the American Museum of Natural History. Over the 1920s and 1930s, this became the focus of an ever-increasing publicity campaign, as Messmore & Damon exhibited prehistoric automata in department stores, the media, and the Chicago World Fair of 1933-34. These displays were hugely popular and widely discussed, drawing from the increasing public appeal of paleontology. Mixing commercial entertainment with invocations of scientific value, Messmore & Damon's prehistoric creations offer a window into the meaning and popularity of the deep time sciences in early-twentieth century America, and the links between science and spectacle in this period. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. [Water pipelines conduits and urban sanitation in Cartagena in the beginning of the twentieth century].

    Science.gov (United States)

    Orrego, A L

    2000-01-01

    Throughout its history, Cartagena de Indias, a seaport in the Colombian Caribbean, has been handicapped for not offering salubrious conditions to its people and visitors. The lack of an aqueduct and a sewerage system was an impairment to progress. For nearly forty years (1890-1930) these problems have caused a myriad of medical discourses formulated by scientists, technicians and politicians. Cartagena's contribution to solve the sanitation problem in cities has consisted in making use of engineers' knowledge. The construction of urban facilities in the beginning of the twentieth century required a more technical knowledge, one which would advance a comprehensive solution to the water problem, ensure sufficient supply and efficient drainage. Thus, in the last turn of the century, the medical doctor is no longer the only authoritative voice when it comes to the management of urban life. The construction works which require an engineer, involving him in public health, have drawn a distinction between "hygiene" and "sanitary science".

  14. Women and political struggles: achievements and limitations lived in the second half of twentieth century

    Directory of Open Access Journals (Sweden)

    Flávia Fernandes de Carvalhaes

    2016-06-01

    Full Text Available The second half of the twentieth century was a period marked by important achievements and setbacks in the struggle for women's rights field. This study mapped out and described part of speeches, images and movements undertaken in that historical period and its effects on people's lives. Adopting a perspective of historical and theoretical analysis, the description looked up, first, the struggles carried out in some countries of Europe and the United States, highlighting its main challenges and difficulties. Then, the struggles undertaken are mapped in Brazil, with the analysis axis facing women inequality. Finally, it is considered that the political struggles carried out in the analyzed period had as greatest merits the disruption and exploitation of gender boundaries.

  15. Linguistic Capital and Its Transformation in the History of Russian in the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Viktor Živov

    2013-02-01

    Full Text Available Standard language is conceptualized as linguistic capital, in terms of Pierre Bourdieu’s sociology. The Twentieth century in Russia was an epoch of revolutions; linguistic developments in revolutionary and post-revolutionary situations may be efficiently analyzed as transformations of linguistic capital: the old linguistic capital is discredited in the course of a cultural revolution and revolutionary linguistic usage becomes new linguistic capital. This process is characterized in Russia (from 1910 through to the 1920s and again in the 1980s and 1990s by the extensive use of borrowings, vulgar and jargon words, obscene expressions. The end of cultural revolutions is accompanied by the emergence of a new elite and by partial restoration of the old linguistic capital; it is appropriated by the new elite and adjusted to their demands. The article describes two cycles of these developments in the period from 1917 up to the present.

  16. An introduction to the poetics of sacred sound in twentieth-century music

    Directory of Open Access Journals (Sweden)

    Luigi Antonio Irlandini

    2013-12-01

    Full Text Available Along the twentieth century has occurred the beginning of a fusion between two very different horizons: Western musical composition and Hindu sonic theology. The essential content of this theology and the changes in Western musical language and aesthetics, society and culture which have allowed this fusion to take place are briefly outlined. Instrumental and vocal works by Karlheinz Stockhausen, Giacinto Scelsi, Michael Vetter and David Hykes provide specific examples and, in particular, raise the predicament between mysticism and rationalism, manifested in the dichotomy ècriture/inspiration. The study proceeds investigating the connections between music and meditation. In this context, overtone singing appears as a musical and meditative practice. The incorporation of this non-European or ancient vocal technique is evaluated as a dawning horizon in Western music. Overtone singing has required a practical emphasis through improvisation, suggesting a new musical praxis that does not separate composition from performance.

  17. Hidden in plain sight marketing prescription drugs to consumers in the twentieth century.

    Science.gov (United States)

    Greene, Jeremy A; Herzberg, David

    2010-05-01

    Although the public health impact of direct-to-consumer (DTC) pharmaceutical advertising remains a subject of great controversy, such promotion is typically understood as a recent phenomenon permitted only by changes in federal regulation of print and broadcast advertising over the past two decades. But today's omnipresent ads are only the most recent chapter in a longer history of DTC pharmaceutical promotion (including the ghostwriting of popular articles, organization of public-relations events, and implicit advertising of products to consumers) stretching back over the twentieth century. We use trade literature and archival materials to examine the continuity of efforts to promote prescription drugs to consumers and to better grapple with the public health significance of contemporary pharmaceutical marketing practices.

  18. Chinese Buddhist Nuns in the Twentieth Century: A Case Study in Wuhan

    Directory of Open Access Journals (Sweden)

    Yuan Yuan

    2015-02-01

    Full Text Available In this paper, through working at the intersection of the works on nationalism and women, and the literature on Buddhist nuns during the Republican period, I aim to take up questions of gender relations in the broader studies of Buddhism and Buddhist modernization. I explore the Buddhist nuns' movement by examining the establishment of various academies for female Buddhists. I also analyze the writings by female Buddhists in the twentieth century. In so doing, I argue that the Buddhist nuns' revival movement fitted into the broader women's liberation discourse and the national modernization project during this time. This paper promises to provide insights into the history of women and nationalism from a Buddhist perspective, and shed light on gender-related issues of modern Chinese Buddhism in the course of China's modernization.

  19. The Establishment of a Car-Based Leisure Regime in Twentieth Century Europe

    DEFF Research Database (Denmark)

    Cassamagnaghi, Silvia; Moretto, Giovanni; Wagner, Michael

    – despite collective Soviet politics – a “private” dream: a private property good for private use. It allowed, for the very first time, mobility (even if relative…) and freedom of travelling. Owning a car permitted to organize the leisure independently from the prearranged forms of leisure set by the State......Comparative analysis of tourism and of its development in three different countries – Denmark, Italy and Soviet Union – has revealed the importance of the car as the keystone for changes in the habits of leisure time consumption all over in Europe. Even considering the specific features (social......, economic and political) of each country, and the different decades in which this phenomenon has occurred, “individual” travel and stay has become, in Twentieth Century, the characteristics of dominance over other forms of organized and “collective” tourism. “Gentlemen, we do not make this tour to drive. We...

  20. Increase of heterozygosity in a growing population of lesser kestrels

    OpenAIRE

    Ortego, Joaquín; Aparicio, José Miguel; Calabuig, Gustau; Cordero, Pedro J.

    2007-01-01

    The lesser kestrel (Falco naumanni) suffered a sharp population decline over much of its European distribution range in the middle of the twentieth century. Still declining in some areas, the species has recently experienced a notable population recovery in certain regions. We examined the genetic diversity variation in a growing population of lesser kestrels from Central Spain over a 6-year period (2000–2005). The population studied showed a rapid demographic expansion, increasing in the num...

  1. Internal atmospheric noise characteristics in twentieth century coupled atmosphere-ocean model simulations

    Science.gov (United States)

    Colfescu, Ioana; Schneider, Edwin K.

    2017-09-01

    The statistical characteristics of the atmospheric internal variability (hereafter internal atmospheric noise) for surface pressure (PS) in twentieth century simulations of a coupled general circulation model are documented. The atmospheric noise is determined from daily post-industrial (1871-1998) Community Climate System Model 3 simulations by removing the SST and externally forced responses from the total fields. The forced responses are found from atmosphere-only simulations forced by the SST and external forcing of the coupled runs. However, we do not address the influence of the SST variability on the synoptic scale high frequency weather noise.The spatial patterns of the main seasonal modes of atmospheric noise variability are found for boreal winter and summer from empirical orthogonal function analyses performed globally and for various regions, including the North Atlantic, the North Pacific, and the equatorial Pacific. The temporal characteristics of the modes are illustrated by power spectra and probability density functions (PDF) of the principal components (PC). Our findings show that, for two different realizations of noise, the variability is dominated by large scale spatial structures of the atmospheric noise that resemble observed patterns, and that their relative amplitudes in the CGCM and AGCM simulations are very similar. The regional expression of the dominant global mode, a seasonally dependent AO-like or AAO-like pattern is also found in the regional analyses, with similar time dependence. The PCs in the CGCM and the corresponding SST forced AGCM simulations are uncorrelated, but the spectra and PDFs of the CGCM and AGCM PCs are similar.The temporal structures of the noise PCs are white at timescales larger than few months, so that these modes can be thought of as stochastic forcings (in time) for the climate system. The PDFs of the noise PCs are not statistically distinguishable from Gaussian distributions with the same standard deviation

  2. Three twentieth-century multiauthored neurological handbooks--a historical analysis and bibliometric comparison.

    Science.gov (United States)

    Koehler, Peter J; Stahnisch, Frank W

    2014-01-01

    The emergence of neurology as a separate specialty from internal medicine and psychiatry took several decades, starting at the end of the nineteenth century. This can be adequately reconstructed by focusing on the establishment of specialized journals, societies, university chairs, the invention and application of specific instruments, medical practices, and certainly also the publication of pivotal textbooks in the field. Particularly around 1900, the German-speaking countries played an integral role in this process. In this article, one aspect is extensively explored, notably the publication (in the twentieth century) of three comprehensive and influential multivolume and multiauthor handbooks entirely devoted to neurology. All available volumes of Max Lewandowsky's Handbuch der Neurologie (1910-1914) and the Handbuch der Neurologie (1935-1937) of Oswald Bumke and Otfrid Foerster were analyzed. The handbooks were then compared with Pierre Vinken's and George Bruyn's Handbook of Clinical Neurology (1968-2002). Over the span of nearly a century these publications became ever more comprehensive and developed into a global, encompassing project as is reflected in the increasing number of foreign authors. Whereas the first two handbooks were published mainly in German, "Vinken & Bruyn" was eventually published entirely in English, indicating the general changes in the scientific language of neurology after World War II. Distinctions include the uniformity of the series, manner of editorial involvement, thematic comprehensiveness, inclusion of volume editors in "Vinken & Bruyn," and the provision of index volumes. The increasing use of authorities in various neurological subspecialties is an important factor by which these handbooks contrast with many compact neurological textbooks that were available at the time. For historiographical purposes, the three neurological handbooks considered here were important sources for the general study of the history of medicine and

  3. Three Twentieth-Century Multiauthored Neurological Handbooks – A Historical Analysis and Bibliometric Comparison

    Science.gov (United States)

    Koehler, Peter J.; Stahnisch, Frank W.

    2013-01-01

    The emergence of neurology as a separate specialty from internal medicine and psychiatry took several decades, starting at the end of the nineteenth century. This can be adequately reconstructed by focusing on the establishment of specialized journals, societies, university chairs, the invention and application of specific instruments, medical practices, and certainly also the publication of pivotal textbooks in the field. Particularly around 1900, the German-speaking countries played an integral role in this process. In this article, one aspect is extensively explored, notably the publication (in the twentieth century) of three comprehensive and influential multivolume and multiauthor handbooks entirely devoted to neurology. All available volumes of Max Lewandowsky's Handbuch der Neurologie (1910–1914) and the Handbuch der Neurologie (1935–1937) of Oswald Bumke and Otfrid Foerster were analyzed. The handbooks were then compared with Pierre Vinken's and George Bruyn's Handbook of Clinical Neurology (1968–2002). Over the span of nearly a century these publications became ever more comprehensive and developed into a global, encompassing project as is reflected in the increasing number of foreign authors. Whereas the first two handbooks were published mainly in German, “Vinken & Bruyn” was eventually published entirely in English, indicating the general changes in the scientific language of neurology after World War II. Distinctions include the uniformity of the series, manner of editorial involvement, thematic comprehensiveness, inclusion of volume editors in “Vinken & Bruyn,” and the provision of index volumes. The increasing use of authorities in various neurological subspecialties is an important factor by which these handbooks contrast with many compact neurological textbooks that were available at the time. For historiographical purposes, the three neurological handbooks considered here were important sources for the general study of the history of

  4. Building Baluchitherium and Indricotherium: imperial and international networks in early-twentieth century paleontology.

    Science.gov (United States)

    Manias, Chris

    2015-01-01

    Over the first decades of the twentieth century, the fragmentary remains of a huge prehistoric ungulate were unearthed in scientific expeditions in India, Turkestan and Mongolia. Following channels of formal and informal empire, these were transported to collections in Britain, Russia and the United States. While striking and of immense size, the bones proved extremely difficult to interpret. Alternately naming the creature Paraceratherium, Baluchitherium and Indricotherium, paleontologists Clive Forster-Cooper, Alexei Borissiak and Henry Fairfield Osborn struggled over the reconstruction of this gigantic fossil mammal. However, despite these problems, shared work on the creature served as a focus for collaboration and exchange rather than rivalry between these three scientific communities. Not only did the initial interpretation and analysis depend on pre-existing connections between British and American paleontological institutions, but the need for comparative material, recognition and contacts brought British and American scholars into communication and exchange with their counterparts in the Soviet Union. This article examines these processes. It first uses these excavations as a comparative case-study of different manifestations of colonial science in this period, examining how scholars in the Britain, the Russian Empire and the United States used formal and informal colonial links to Asia to pursue new research. It then moves to examine how the common problem of reconstructing this giant animal drew metropolitan scientific communities together, at least for a time. The construction of the Baluchitherium and Indricotherium illustrates the drives to expand research both imperially and internationally in the early-twentieth century, but also the continual problems in resources, institutionalization, transport and communication that could run up against scientific work.

  5. Climate change in Hungary during the twentieth century according to Feddema

    Science.gov (United States)

    Breuer, Hajnalka; Ács, Ferenc; Skarbit, Nóra

    2017-02-01

    Climate change in Hungary during the twentieth century is analyzed using Feddema's original scheme suitable for global scale applications (F-GS) and Feddema's fine-tuned scheme designed for Hungarian applications (F-HU). Input data of precipitation (P) and air temperature (T) are taken from the Climatic Research Unit (CRU) TS 1.2 database constructing P-T data referring to three 30-year periods (1901-1930, 1941-1970, 1971-2000) and two 50-year periods (1901-1950, 1951-2000). The method and data organizational effects are compared using these schemes and data sets. The results show that the evaluation of the climate change process depends much more on the methodological rather than on data organizational effects. Methodical fine-tuning effects considerably improved the spatial distribution, while the organization of data improved the insight into the dynamic of the processes. According to F-GS, there is no climate change on 76.7 % of Hungarian territory. According to F-HU, such areas amount to only 38.5 %. The main climate change process for F-GS is drying, while for F-HU drying and warming beside either drying or warming. For both models, the most climate change affected areas are characterized by higher altitudes, such as in the Mecsek and Villány Mountains (geographical region Transdanubia), in the Bükk Mountains (geographical region North Hungarian Mountains), and in the region of the so-called Danube Bend. The spatially most realistic climate description is obtained by using F-HU and the 30-year data sets. It is to be noted that Köppen's, Holdridge's, and Thornthwaite's methods are less suitable than F-HU for representing the process of climate change in Hungary in the twentieth century.

  6. Heritage and Observatories in Brazil at the Turn of the Twentieth Century: an Overview

    Science.gov (United States)

    Granato, Marcus

    The first systematic asronomical observations in the southern hemisphere were in Pernambuco, northeastern Brazil, in the short period of Dutch rule in the region (1637-1644). Later, in the late nineteenth and early twentieth centuries, there were three observatories on Brazilian soil: Imperial Observatório do Rio de Janeiro, Observatório da Escola Politecnica, both in Rio de Janeiro and Observatório Central, in the southern city of Porto Alegre. The first was created by Imperial decree by D. Pedro I, on 15 October 1827, while the second, linked to Universidade do Brasil, was established on 5 July 1881. The third was planned in 1889, but only inaugurated on 24 January 1908 as part of the Escola de Engenharia. All three institutions exist to this day, and their scientific instruments of historical value are included in cultural heritage preservation projects. The largest collection of this kind of objects is at Museu de Astronomia e Ciéncias Afins (MAST), most of whose 2000 artefacts come from the Imperial Observatory (today the National Observatory). Many of them were produced in Germany by manufacturers such as Gustav Heyde, Carl Zeiss, Askania-Werke, Carl Bamberg and Max Kohl. The buildings of the Observatório Central (1921) and Observatório Nacional (1921) are listed by federal and state heritage protection agencies, particularly because they were purpose built for astronomical research and have architectural features typical of the late nineteenth and early twentieth centuries that have not been altered over the years.

  7. Twentieth century warming of the tropical Atlantic captured by Sr-U paleothermometry

    Science.gov (United States)

    Alpert, Alice E.; Cohen, Anne L.; Oppo, Delia W.; DeCarlo, Thomas M.; Gaetani, Glenn A.; Hernandez-Delgado, Edwin A.; Winter, Amos; Gonneea, Meagan

    2017-01-01

    Coral skeletons are valuable archives of past ocean conditions. However, interpretation of coral paleotemperature records is confounded by uncertainties associated with single-element ratio thermometers, including Sr/Ca. A new approach, Sr-U, uses U/Ca to constrain the influence of Rayleigh fractionation on Sr/Ca. Here we build on the initial Pacific Porites Sr-U calibration to include multiple Atlantic and Pacific coral genera from multiple coral reef locations spanning a temperature range of 23.15–30.12°C. Accounting for the wintertime growth cessation of one Bermuda coral, we show that Sr-U is strongly correlated with the average water temperature at each location (r2 = 0.91, P period 1900–1996 is within 0.12°C of the average instrumental temperature at this site and captures the twentieth century warming trend of 0.06°C per decade. Sr-U also captures the timing of multiyear variability but with higher amplitude than implied by the instrumental data. Mean Sr-U temperatures and patterns of multiyear variability were replicated in a second coral in the same grid box. Conversely, Sr/Ca records from the same two corals were inconsistent with each other and failed to capture absolute sea temperatures, timing of multiyear variability, or the twentieth century warming trend. Our results suggest that coral Sr-U paleothermometry is a promising new tool for reconstruction of past ocean temperatures.

  8. Comparative study of white porcelain from the common use of nineteenth and twentieth centuries with PXRF

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Wislley Dueli da; Appoloni, Carlos Roberto [Universidade Estadual de Londrina (UEL), PR (Brazil)

    2011-07-01

    Full text: The technique of X-ray fluorescence (XRF) is widely used for qualitative and quantitative researches on the chemical composition of various types of samples, such as archaeological, art and cultural heritage materials or samples. The great advantage of this technique is that it allows a nondestructive and simultaneous multielement analysis. It has a low cost and portable system device that can be used in situ. The study of archaeological artifacts and cultural heritage by means of analytical techniques with hand held devices becomes increasingly routine today. Several types of portable energy dispersive X-ray fluorescence (EDXRF) have been used in many different situations involving in situ analysis covering a wide range of geometries, detectors, voltage and current applied in the X-ray tubes. This study aims to identify and compare the main elements that make up samples of ceramic pottery for common use by the late nineteenth and early and late twentieth century, as a way of using the methodology of analysis by EDXRF equipment PXRF - LFNA - 02. Being able to identify that the key element present in the glaze of ceramics from the early twentieth century was the Pb, it was possible to classify the samples as faience cream ware and not pearlware as it was guided by conventional archaeological analysis, where the rating was based only on color enamel porcelain. Elements such as K, Ca, Cr, Mn, Fe, Co, Zn, Rb, Sr, Zr are also found in different concentrations depending on the clay used in the manufacture of earthenware, maker of the period and that it was produced. From analysis of the type EDXRF is possible to compare different manufacturing techniques, both in enamel and in ceramic slurry and often even the color of his pieces. (author)

  9. Social Skills: Adolf Meyer's Revision of Clinical Skill for the New Psychiatry of the Twentieth Century.

    Science.gov (United States)

    Lamb, Susan

    2015-07-01

    Adolf Meyer (1866-1950) exercised considerable influence over the development of Anglo-American psychiatry during the first half of the twentieth century. The concepts and techniques he implemented at his prominent Phipps Psychiatric Clinic at Johns Hopkins remain important to psychiatric practice and neuro-scientific research today. In the 1890s, Meyer revised scientific medicine's traditional notion of clinical skill to serve what he called the 'New Psychiatry', a clinical discipline that embodied social and scientific ideals shared with other 'new' progressive reform movements in the United States. This revision conformed to his concept of psychobiology - his biological theory of mind and mental disorders - and accorded with his definition of scientific medicine as a unity of clinical-pathological methods and therapeutics. Combining insights from evolutionary biology, neuron theory and American pragmatist philosophy, Meyer concluded that subjective experience and social behaviour were functions of human biology. In addition to the time-honoured techniques devised to exploit the material data of the diseased body - observing and recording in the clinic, dissecting in the morgue and conducting histological experiments in the laboratory - he insisted that psychiatrists must also be skilled at wielding social interaction and interpersonal relationships as investigative and therapeutic tools in order to conceptualise, collect, analyse and apply the ephemeral data of 'social adaptation'. An examination of his clinical practices and teaching at Johns Hopkins between 1913 and 1917 shows how particular historical and intellectual contexts shaped Meyer's conceptualisation of social behaviour as a biological function and, subsequently, his new vision of clinical skill for twentieth-century psychiatry.

  10. Twentieth-century Victorian: Arthur Conan Doyle and the "Strand Magazine," 1891–1930, by Jonathan Cranfield [book review

    Directory of Open Access Journals (Sweden)

    Anne-Charlotte Mecklenburg

    2017-03-01

    Full Text Available Review of Jonathan Cranfield, Twentieth-century Victorian: Arthur Conan Doyle and the "Strand Magazine," 1891–1930. Edinburgh: Edinburgh University Press, 2016, hardcover, £75 (272p ISBN 978-1474406758; e-book, £75, ISBN 978-1474406772.

  11. Twentieth-century Victorian: Arthur Conan Doyle and the "Strand Magazine," 1891–1930, by Jonathan Cranfield [book review

    Directory of Open Access Journals (Sweden)

    Anne-Charlotte Mecklenburg

    2017-03-01

    Full Text Available Book review of Jonathan Cranfield, Twentieth-century Victorian: Arthur Conan Doyle and the "Strand Magazine," 1891–1930. Edinburgh: Edinburgh University Press, 2016, hardcover, £75 (272p ISBN 978-1474406758; e-book, £75, ISBN 978-1474406772.

  12. The Scientific Enlightenment System in Russia in the Early Twentieth Century as a Model for Popularizing Science

    Science.gov (United States)

    Balashova, Yuliya B.

    2016-01-01

    This research reconstructs the traditions of scientific enlightenment in Russia. The turn of the nineteenth and twentieth centuries was chosen as the most representative period. The modern age saw the establishment of the optimal model for advancing science in the global context and its crucial segment--Russian science. This period was…

  13. Twentieth-century global-mean sea-level rise: is the whole greater than the sum of the parts?

    NARCIS (Netherlands)

    Gregory, J.M.; White, N.J.; Church, J.A.; Bierkens, M.F.P.; Box, J.E.; Broeke, M.R. van den; Cogley, J.G.; Fettweis, X.; Hanna, E.; Huybrechts, P.; Konikow, L.F.; Leclercq, P.W.; Marzeion, B.; Oerlemans, J.; Tamisiea, E.; Wada, Y.

    2012-01-01

    Confidence in projections of global-mean sea level rise (GMSLR) depends on an ability to account for GMSLR during the twentieth century. There are contributions from ocean thermal expansion, mass loss from glaciers and ice sheets, groundwater extraction, and reservoir impoundment. Progress has been

  14. Public Expenditure on Education and Economic Growth in the USA in the Nineteenth and Twentieth Centuries in Comparative Perspective

    Science.gov (United States)

    Carpentier, Vincent

    2006-01-01

    Earlier studies of France, Germany and the UK suggest that a common framework exists to explain the relationship between public expenditure on education and economic growth in the nineteenth and twentieth centuries. This article shows that while a similar relationship exists in the USA, US policies were particularly committed to the educational…

  15. The creation of play spaces in twentieth-century Amsterdam: from an intervention of civil actors to a public policy

    NARCIS (Netherlands)

    Verstrate, L.; Karsten, L.

    2011-01-01

    This case study uncovers a turning point in the production of play space in Amsterdam. Whereas over the first half of the twentieth century the creation of play spaces used to be the primary responsibility of the Amsterdam civil society, this situation started to change after the Second World War. B

  16. YINSHUN'S RECOVERY OF SHIZHU PIPOSHA LUN A MADHYAMAKA-BASED PURE LAND PRACTICE IN TWENTIETH-CENTURY TAIWAN

    NARCIS (Netherlands)

    Travagnin, Stefania

    2013-01-01

    Yinshun (1906-2005) is regarded as one of the eminent monks of twentieth-century Chinese Buddhism. In the mission of reinventing Chinese Buddhism Yinshun engaged particularly in the revival and restatement of Madhyamaka. His interpretation of Ngrjuna's texts, the reassessment of the links between pr

  17. Those Who Served: Report of the Twentieth Century Fund Task Force on Policies Toward Veterans. Background Paper.

    Science.gov (United States)

    Taussig, Michael K.

    Veterans' policies and programs are examined by a task force of the Twentieth Century Fund. Part 1, the report of the task force, includes sections on the rationale for veterans benefits, recommendations for further benefits and programs, and a dissenting opinion by one task force member. Recommendations are summarized into five basic areas: (1)…

  18. The Yankees of Europe? A New View on Technology and Productivity in German Manufacturing in the Early Twentieth Century

    NARCIS (Netherlands)

    Timmer, Marcel P.; Veenstra, Joost; Woltjer, P.J.

    2016-01-01

    Labor productivity in German manufacturing lagged behind the United States in the early twentieth century. Traditionally, this is attributed to dichotomous technology paths across the Atlantic. However, various industry case studies suggest rapid diffusion of U.S. technologies in Germany. We develop

  19. Educational Ideas in Geography Education in Sweden during the Nineteenth and Early Twentieth Centuries: The Relationship between Maps and Texts

    Science.gov (United States)

    Hennerdal, Pontus

    2015-01-01

    Descriptions of the geography education of the nineteenth and early twentieth centuries in Sweden are typically offered to contrast with current ideas in geography education, and the content of geography textbooks is the focus of this comparison. The role of maps and visual pedagogy are ignored, and the educational ideas developed from regional…

  20. "El destierro de los Chinos": Popular Perspectives on Chinese-Mexican Intermarriage in the Early Twentieth Century

    Science.gov (United States)

    Romero, Robert Chao

    2007-01-01

    This essay examines Chinese-Mexican interracial marriage during the early twentieth century through the lens of Mexican popular culture. Comedy, poetry, cartoons, and musical recordings of the time portrayed these marriages as relationships of abuse, slavery, and neglect, and rejected the offspring of such unions as subhuman and unworthy of full…

  1. Educational Ideas in Geography Education in Sweden during the Nineteenth and Early Twentieth Centuries: The Relationship between Maps and Texts

    Science.gov (United States)

    Hennerdal, Pontus

    2015-01-01

    Descriptions of the geography education of the nineteenth and early twentieth centuries in Sweden are typically offered to contrast with current ideas in geography education, and the content of geography textbooks is the focus of this comparison. The role of maps and visual pedagogy are ignored, and the educational ideas developed from regional…

  2. The Yankees of Europe? A New View on Technology and Productivity in German Manufacturing in the Early Twentieth Century

    NARCIS (Netherlands)

    Timmer, Marcel P.; Veenstra, Joost; Woltjer, Pieter J.

    Labor productivity in German manufacturing lagged persistently behind the United States in the early twentieth century. Traditionally, this is attributed to dichotomous technology paths across the Atlantic. However, various industry case studies suggest rapid diffusion of U.S. technologies in

  3. Chemistry and Chemical Education through Text and Image: Analysis of Twentieth Century Textbooks Used in Brazilian Context

    Science.gov (United States)

    Souza, Karina Ap F. D.; Porto, Paulo Alves

    2012-01-01

    Assuming that textbooks give literary expression to cultural and ideological values of a nation or group, we propose the analysis of chemistry textbooks used in Brazilian universities throughout the twentieth century. We analyzed iconographic and textual aspects of 31 textbooks which had significant diffusion in the context of Brazilian…

  4. The Democratic School and the Pedagogy of Janusz Korczak: A Model of Early Twentieth Century Reform in Modern Israel

    Science.gov (United States)

    Engel, Liba H.

    2013-01-01

    This article explores the history and pedagogy of Janusz Korczak within the context of his contemporary early Twentieth-Century European Innovative Educators which include Maria Montessori, Homer Lane, A.S. Neill, and Anton Semyonovitch Makarenko. The pedagogies of the aforementioned are compared and contrasted within the literature.

  5. Working women in France, nineteenth and twentieth centuries. Where, when, and which women were in work at marriage?

    NARCIS (Netherlands)

    Zijdeman, Richard L.; van Leeuwen, Marco H D; Rébaudo, Danièle; Pélissier, Jean Pierre

    2014-01-01

    We look at women's labour force participation for the whole of France in the nineteenth and twentieth centuries. We study to what extent young women were working at the time of their marriage, in which occupations, and how differences in labour force participation might be explained. Using a sample

  6. BOOK REVIEW: Quantum Generations. A history of physics in the twentieth century

    Science.gov (United States)

    Brown, Neil

    2000-03-01

    Physics has a long history, but more physics has been discovered in the twentieth century than in all previous eras together. That in itself would be a sufficient justification for a history of physics in the twentieth century, but the end of the previous century also marked a discontinuity, from Newtonian classical physics to relativity and quantum mechanics. If any single event marks the start of the process it is the discovery of x-rays in 1895, and Kragh's century spans from about 1895 to about 1995. It is, of course, too much for a single volume, even a large one, and Kragh recognizes from the outset that he has to be selective and concentrate on those subjects that define twentieth-century physics. For the early part of the century the author relies on carefully chosen secondary sources, to avoid the near-impossible task of absorbing a multitude of original papers. The recent period is more difficult, and the sources are articles, reviews, and the recollections of physicists. The book is in three main sections, roughly to the end of World War I, to the end of World War II, and up to 1995, plus a retrospective summary. It deals with more than just discoveries in physics, looking also at physicists and institutions, and at their interactions with the rest of society. The broad outlines of many discoveries are often known to physicists who have no special interest in history, and Kragh is careful to point out where these conventional accounts are inadequate. The first chapters set the scene at the end of the nineteenth century, acknowledging that there was a belief that all the grand underlying principles had been established, but also pointing out that there was a ferment of attempts to reinterpret physics in terms of concepts like vortices and hyperspaces. The history begins with the mould-breaking discoveries of x-rays, radioactivity and the electron. The chapters that follow look at theories about atomic structure, and at quantum physics, relativity and

  7. [Pain and anesthesiology : aspects of the development of modern pain therapy in the twentieth century].

    Science.gov (United States)

    Witte, W

    2011-06-01

    The connection between the development of anesthesiology and pain therapy in the twentieth century is close. The optimistic idea to overcome pain by using general anesthesia derives from the nineteenth century. Treatment of nonsurgical pain remained in the background for a long time and innovations in pain medicine did not improve the insufficient care for patients with postoperative pain. Therapy of chronic pain was mainly surgical and the extreme of this surgical approach was psychosurgery. In the years following World War II leucotomy and lobotomy were established as methods to separate the psychological processing of pain from the experience of pain. Meanwhile, the French "pain surgeon" René Leriche elaborated a theory of pain where chronic pain was no longer seen as a symptom but as a "douleur-maladie", a pain disease. His theory was considered on various occasions but did not gain acceptance before the 1950s. Research in anesthesiology, such as that conducted by the American scientist Henry Beecher separated psyche and physiology with respect to pathological pain. This was contrasted by the approach of clinical anesthesia to pain therapy, which was based on regional anesthesia. The first "pain clinics" were "nerve block clinics". John Bonica, a regional anesthesiologist, extended the framework of pain therapy by introducing multidisciplinary teamwork into the therapy of chronic pain. From today's viewpoint his 1953 monograph The Management of Chronic Pain is a milestone in the development of modern pain therapy. However, Bonica's work did not attain major importance until 1960 when he was appointed to a newly established chair. Gradually, chronic pain was recognized as an independent illness and differentiated as such from acute pain. In 1965 the gate control theory by Melzack and Wall offered a possible explanation for the mechanisms of chronic pain. By the end of the 1970s the spectrum was extended to the biopsychosocial approach which was foremost

  8. Twentieth-century astronomical heritage: the case of the Brazilian National Observatory

    Science.gov (United States)

    Barboza, Christina Helena

    2015-08-01

    The National Observatory of Brazil was created in 1827. It was initially focused on the practical teaching of Astronomy to the students of military and naval academies. Since the mid-nineteenth century to the early twentieth century it was installed over the ruins of a Jesuit church located in the center of Rio de Janeiro, capital of the Brazilian Empire.Due to the constant complaints of its successive directors, the search for a new site to house the Observatory began in 1911. The new headquarters of the institution were located on the hill of São Januário, a little further but still around the city center of Rio de Janeiro. Its inauguration took place in 1921.The main building of the new Observatory was based on one of the Brazilian pavilions of the Turin Exhibition of 1911, and its architecture can be characterized as eclectic. The pavilions intended to house the many telescopes were scattered in a large wooded area. Since 1985 all these facilities are protected by the Federal government, as a consequence of the same initiative that gave birth to the Museum of Astronomy and Related Sciences, which has the custody also of the Observatory’s former instruments, furniture, and documents.Although built in the early twentieth century the National Observatory new facilities reveal astronomical practices typical of the previous century. One of its most important activities was the determination of the legal time, a task that justifies its location in the urban environment. It was also responsible for the organization of expeditions destined to determine the geographical positions of railroads and the borders of Brazil. For this reason, the Museum of Astronomy has currently more than 3,000 portable instruments. Moreover, these instruments belong to the domain of Astronomy, but also to Geodesy, Meteorology, Electricity. Due to the creation of the Museum of Astronomy, this rich collection is now open to public visitation, and has become the object of scholarly

  9. [Physical restraint of patients: historical notes relating to the nineteenth and twentieth century].

    Science.gov (United States)

    Fariña-López, Emilio; Estévez-Guerra, Gabriel J

    2011-03-01

    Physical restraint has been historically considered a necessary procedure to control the behaviour of the mentally ill. In the late eighteenth century moral treatment would pave the way for new initiatives against restraint, such as those instituted by British psychiatrists. They stressed the importance of training and supervision, as well as a minimum staff ratio, as being determining factors in reducing the use of restraint. This philosophy of treatment, despite its benefits, was introduced later and to a lesser extent in the rest of Europe, although, in other countries care was also made more humane through new therapeutic procedures. By contrast, in the United States most psychiatrists disagreed with those who advocated non-restraint, and continued using controversial methods to control the behaviour of patients. In Spain many difficulties hindered the improvement of conditions in institutions, many of which were in a sorry state. The initiatives of a few professionals and some cautious legal advances tried to alleviate the harshness of the treatment methods used. In the early twentieth century professional manuals were already available, which included the care to be given during the application of physical restraints. However it was not until the 1950, when the emergence of new psychotropic drugs and the distribution of important guidelines on the protection of the rights of patients that the widespread use of this procedure would be successfully reduced.

  10. Creeping, drinking, dying: the cinematic portal and the microscopic world of the twentieth-century cell.

    Science.gov (United States)

    Landecker, Hannah

    2011-09-01

    Film scholars have long posed the question of the specificity of the film medium and the apparatus of cinema, asking what is unique to cinema, how it constrains and enables filmmakers and audiences in particular ways that other media do not. This question has rarely been considered in relation to scientific film, and here it is posed within the specific context of cell biology: What does the use oftime-based media such as film coupled with the microscope allow scientists to experience that other visualization practices do not? Examining three episodes in the twentieth-century study of the cell, this article argues that the apparatus ofmicrocinematography constitutes what might be thought of as a technical portal to another world, a door that determines the experience of the world that lies on the other side of it. In this case, the design of apparatuses to capture time-lapsed images enabled the acceleration of cellular time, bringing it into the realm of human perception and experience. Further, the experience of the cellular temporal world was part of a distinct kind of cell biology, one that was focused on behavior rather than structure, focused on the relation between cells, and between the cell and its milieu rather than on cell-intrinsic features such as chromosomes or organelles. As such, the instruments and technical design of the microcinematographic apparatus may be understood as a kind of materialized epistemology, the history of which can elucidate how cinema was and is used to produce scientific knowledge.

  11. Using the Twentieth Century Reanalysis to assess climate variability for the European wind industry

    CERN Document Server

    Bett, Philip E; Clark, Robin T

    2014-01-01

    We characterise the long-term variability of European near-surface wind speeds using 140 years of data from the Twentieth Century Reanalysis (20CR), and consider the potential of such long-baseline climate data sets for wind energy applications. The low resolution of the 20CR would severely restrict its use on its own for wind farm site-screening. We therefore perform a simple statistical calibration to link it to the higher-resolution ERA-Interim data set (ERAI), such that the adjusted 20CR data has the same wind speed distribution at each location as ERAI during their common period. Using this corrected 20CR data set, wind speeds and variability are characterised in terms of the long-term mean, standard deviation, and corresponding trends. Many regions of interest show extremely weak trends on century timescales, but contain large multidecadal variability. Variations in the form of the wind speed distribution are assessed in terms of its deciles; we find that the commonly-used Weibull distribution often pro...

  12. "For ever and ever": Child-raising, domestic workers and emotional labour in twentieth century Britain

    Directory of Open Access Journals (Sweden)

    Lucy Delap

    2011-07-01

    Full Text Available The relationships of physical and emotional labour which exist between children, parents and domestic workers are historically fluid. Different styles of parenting, discourses of social class, and material contexts of care have given rise to very diverse degrees of delegation of childcare to servants. Servants themselves have often invested emotionally in their relationships with children, and the relationship has clearly not been simply commodified in being delegated. However, the relationships that result have sometimes been troubled and ambivalent. A simple narrative of exploitation does little to capture the experiences of servants who cared for children, and the recent historiography of emotions and emotional labour can help to trace a fuller picture. In this paper, I examine the roles of laughter as a form of emotional expression that can shed light on the affects of care – the shared jokes, failed jokes and forms of mockery that characterised the management of servants by mothers who employed them, or the experiences of servants and children in late nineteenth and twentieth century servant-keeping houses.

  13. Theory versus Practice in the Twentieth-Century Search for the Ideal Anaesthetic Gas.

    Science.gov (United States)

    Rae, Ian D

    2016-02-01

    At the beginning of the twentieth century, an anaesthetist could choose between nitrous oxide, chloroform, and ether (diethyl ether) for the induction of painrelieving unconsciousness. By the end of century, the choice was between a small number of fluorinated aliphatic ethers such as Enflurane, Desflurane, and Sevoflurane, and (in some jurisdictions) the rare gas, xenon. Between these endpoints researchers had identified a surprisingly broad range of hydrocarbons, noble gases, organohalogens, and aliphatic ethers that possessed anaesthetic properties. None was entirely satisfactory, but clinicians at various times and in various places employed substances in each of these categories. Behind the search for new anaesthetic gases was a theory of action (Meyer- Overton theory) that was known to be inadequate, but as no alternative was strong enough to displace it the search continued on purely empirical grounds, while lip-service was paid to the theory. By the time a theory couched in more modern terms was proposed, a suite of modern anaesthetic gases was in place, and there have been no attempts to use that theory to drive a new search.

  14. Empowered objects, powerless subjects: citizenship, religion, and political representation in twentieth-century Cuba

    Directory of Open Access Journals (Sweden)

    Olivia Maria Gomes da Cunha

    2008-12-01

    Full Text Available [First paragraph] Measures of Equality: Social Science, Citizenship, and Race in Cuba, 1902-1940. Alejandra Marina Bronfman. Chapel Hill: University of North Carolina Press, 2004. xi + 234 pp. (Paper US$ 19.95 Afro-Cuban Religiosity, Revolution, and National Identity. Christine Ayorinde. Gainesville: University Press of Florida, 2004. ix + 283 pp. (Cloth US$ 59.95 In the last ten years, research topics such as race and nation have been privileged areas for the historical and anthropological understanding of Caribbean and Latin American societies. Regarding Cuba in particular, social scientists have dedicated important scholarship to these issues by mapping conceptions of citizenship and political representation, while situating them within a broader debate on the making of the new postcolonial and republican society at the beginning of the twentieth century. By pursuing different aims and following distinct approaches, Alejandra Bronfman and Christine Ayorinde have made contributions to this academic literature. Through divergent theoretical and methodological perspectives, both of their books explore alternative ways of interpreting the making of the nation founded upon a multiple and fluid rhetoric of race.

  15. The fire ant wars. Nature and science in the pesticide controversies of the late twentieth century.

    Science.gov (United States)

    Buhs, Joshua Blu

    2002-09-01

    This essay uses an approach borrowed from environmental history to investigate the interaction of science and nature in a late twentieth-century controversy. This debate, over the proper response to fire ants that had been imported into the American South accidentally and then spread across the region, pitted Rachel Carson and loosely federated groups of conservationists, scientists, and citizens against the U.S. Department of Agriculture. The analysis falls into three sections: an examination of the natural history of the ants; an examination of the views of the competing factions; and an examination of how those views, transformed into action, affected the natural world. Both sides saw the ants in terms of a constellation of beliefs about the relationship between nature, science, and democracy. As various ideas were put into play, they interacted with the natural history of the insects in unexpected ways--and with consequences for the cultural authority of the antagonists. Combining insights from the history of science and environmental history helps explain how scientists gain and lose cultural authority and, more fundamentally, allows for an examination of how nature can be integrated into the history of science.

  16. Dark, bloody and savage: Twentieth-century European violence and its narratives

    Directory of Open Access Journals (Sweden)

    Rodrigo, Javier

    2014-12-01

    Full Text Available This paper looks at major European twentieth-century narratives and interpretations that have seen it as an age of violence, terror and genocide. Using examples from historiographical debate and the analysis of specific historical processes (including the debates on genocide, concentrationary systems, civil wars and the Holocaust, it addresses both the characteristics of those narratives and some of their limitations and conceptual edges. Finally, the conceptual proposal put forward seeks to analyze, through historical contingency, continuities and discontinuities in the history of European collective violence.Este artículo propone una mirada a algunas de las grandes narrativas e interpretaciones sobre el siglo XX europeo que lo han visto como una centuria de violencia, terror y genocidio. A través de algunos ejemplos de debates historiográficos y de análisis de procesos históricos concretos (como los debates sobre el genocidio, los sistemas concentracionarios, las guerras civiles o el Holocausto, se abordan tanto las características de esas narrativas como algunos de sus límites y aristas. Al final, se adelanta una propuesta conceptual para analizar desde la contingencia histórica las continuidades y discontinuidades en la historia de la violencia colectiva europea.

  17. Are We Them? Textual and Literary Representations of the Chinese in Twentieth-Century Thailand

    Directory of Open Access Journals (Sweden)

    Thak Chaloemtiarana

    2014-12-01

    Full Text Available King Vajiravudh famously published an essay titled Jews of the Orient in 1914 demonizing the Chinese in Siam as ingrates and parasites. The local Chinese became the “Other Within” in the Thai nation that the king was trying to establish. Whether his reaction to the local Chinese was fueled by ire over the recent strike by the Chinese which paralyzed Bangkok, or a reflection of his English education and exposure to European anti-Semitism, is not the focus of my concern. My interest for this exercise is to study how the Chinese in Siam/Thailand are portrayed in Thai language texts, that is, prose fiction and non-fiction produced in the twentieth century (I will not include related areas such as movies, television drama, music, and cartoons. This study does not involve an exhaustive review of all texts but will focus on a few well-known and popular ones. I would like to know whether King Vajiravudh’s portrayal of the Chinese is reflected in subsequent literary production or muted by other realities that existed in Thai society, and how the production of texts on the local Chinese changed over time. More importantly, I am very curious to know how this issue is played out in neighboring countries, especially the Philippines, Indonesia, Malaysia, Burma, Laos, and Cambodia, countries where the “assimilation” of the Chinese into the majority culture happens in varying degrees.

  18. Writing the history of virology in the twentieth century: Discovery, disciplines, and conceptual change.

    Science.gov (United States)

    Méthot, Pierre-Olivier

    2016-10-01

    Concerned with the study of viruses and the diseases they cause, virology is now a well-established scientific discipline. Whereas aspects of its history from the late nineteenth to the mid-twentieth century have often been recounted through a number of detailed case studies, few general discussions of the historiography of virology have been offered. Looking at the ways in which the history of virology has been told, this article examines a number of debates among scientists and historians of biology and show how they are based on a different understanding of notions such as "discipline", of processes such as "scientific discovery" as well as on distinct views about what the history of science is and how it should be written (the opposition between "longue durée" and "micro-history" or between history of "concepts" versus "experimental methods"). The analysis provided here also suggests that a richer historiography of virology will require looking at the variations over time of the relations between conceptual, technological, and institutional factors that fostered its development at the intersection of several other scientific fields in the life sciences.

  19. The campus in the twentieth century: The urban campus in Chicago from 1890 to 1965

    Directory of Open Access Journals (Sweden)

    Marco Giliberti

    2011-01-01

    Full Text Available After the Civil War, when socio political reorganisation was urgently needed, American universities contributed to the process of re establishing the internal equilibrium of power within the nation. Thus an attempt was made to reinforce the political parties and develop regions as politically discrete territorial entities that were relatively manageable. In the twentieth century the effect of this policy of local centralisation at the regional level, in conjunction with the opportunity offered by the need to develop more effective city governance, was translated into the awareness that a major contribution of academia to politics is to help re establish the parameters of governability for the entire country. With the goal of documenting and exploring some key relations between campus plans and city planning in Chicago, this paper illustrates a number of campus plans and planning strategies in which “the city” can be thought of as a metonym for the entire society. Nexuses between campus and city planning can be revealed from the creation of the campus of the University of Chicago in 1890 to the first half of the 1960s.

  20. The German genius Europe's third renaissance, the second scientific revolution, and the twentieth century

    CERN Document Server

    Watson, Peter

    2010-01-01

    Peter Watson's virtuoso sweep through modern German thought and culture, from 1750 to the present day, will challenge and confound both the stereotypes the world has of Germany and those that Germany has of itself. From the end of the Baroque era and the death of Bach to the rise of Hitler in 1933, Germany was transformed from a poor relation among Western nations into a dominant intellectual and cultural force—more creative and influential than France, Britain, Italy, Holland, and the United States. In the early decades of the twentieth century, German artists, writers, scholars, philosophers, scientists, and engineers were leading their freshly unified country to new and unimagined heights. By 1933, Germans had won more Nobel Prizes than any other nationals, and more than the British and Americans combined. Yet this remarkable genius was cut down in its prime by Adolf Hitler and his disastrous Third Reich—a brutal legacy that has overshadowed the nation's achievements ever since. How did the Germans t...

  1. Decadal potential predictability of upper ocean heat content over the twentieth century

    Science.gov (United States)

    Li, Shujun; Zhang, Liping; Wu, Lixin

    2017-02-01

    The statistical method, Average Predictability Time (APT) decomposition, is used in the present paper to estimate the decadal predictability of upper ocean heat content over the global ocean, North Pacific and North Atlantic, respectively. The twentieth century simulations from CMIP5 outputs are the main data sources in this study. On global scale, the leading predictable component is characterized by a warming trend over the majority of oceans, which is related to the anthropogenic forced response. The second predictable component has significant loadings in the North Atlantic, especially in the subtropical region, which originates from the Atlantic Multidecadal Oscillation (AMO) predictability. To separate interactions among different ocean basins, we further maximize APT in individual North Pacific and North Atlantic oceans. It is found that the second and the third predictable component in North Pacific are significantly correlated with the well-known North Pacific Gyre Oscillation mode and the Pacific Decadal Oscillation respectively. Upper limit prediction skill of these two components are on the order of 6 years. In contrast, the most predictable component derived from the North Atlantic features an AMO-like spatial structure with its prediction skill up to 18 years, while the basin mode due to global warming only exists as the third component. This indicates the interdecadal variability in the North Atlantic is strong enough to mask the anthropogenic climate signals. Furthermore, predictability in the real world is also investigated and compared with model results by using observation-based data.

  2. Economic performance and public concerns about social class in twentieth-century books.

    Science.gov (United States)

    Chen, Yunsong; Yan, Fei

    2016-09-01

    What is the association between macroeconomic conditions and public perceptions of social class? Applying a novel approach based on the Google Books N-gram corpus, this study addresses the relationship between public concerns about social class and economic conditions throughout the twentieth century. The usage of class-related words/phrases, or "literary references to class," in American English-language books is related to US economic performance and income inequality. The findings of this study demonstrate that economic conditions play a significant role in literary references to class throughout the century, whereas income inequality does not. Similar results are obtained from further analyses using alternative measures of class concerns as well as different corpora of English Fiction and the New York Times. We add to the social class literature by showing that the long-term temporal dynamics of an economy can be exhibited by aggregate class concerns. The application of massive culture-wide content analysis using data of unprecedented size also represents a contribution to the literature. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Experiments and Research Programmes. Revisiting Vitalism/Non-Vitalism Debate in Early Twentieth Century

    Directory of Open Access Journals (Sweden)

    Bijoy MUKHERJEE

    2012-06-01

    Full Text Available Debates in the philosophy of science typically take place around issues such as realism and theory change. Recently, the debate has been reformulated to bring in the role of experiments in the context of theory change. As regards realism, Ian Hacking’s contribution has been to introduce ‘intervention’ as the basis of realism. He also proposed, following Imre Lakatos, to replace the issue of truth with progress and rationality. In this context we examine the case of the vitalism — reductionism debate in biology inspired by the works of Indian physicist-turned-biologist Jagadish Chandra Bose (1858–1937, in the early twentieth century. Both camps had their characteristic hardcores. Vitalists led by John S. Burdon-Sanderson and Augustus D. Waller accepted religious metaphysics to support their research programme, which ultimately degenerated. Bose worked more with the ideals of science such as Occam’s razor, large-scale systematization of phenomena and novel prediction. I argue that his religious metaphysics, instead of acting as a protective shield, helped him to consolidate his position and allowed further problem shift resulting in a research programme that involved consciousness too. His research programme remains relevant even today.

  4. Using the Twentieth Century Reanalysis to assess climate variability for the European wind industry

    Science.gov (United States)

    Bett, Philip E.; Thornton, Hazel E.; Clark, Robin T.

    2017-01-01

    We characterise the long-term variability of European near-surface wind speeds using 142 years of data from the Twentieth Century Reanalysis (20CR), and consider the potential of such long-baseline climate data sets for wind energy applications. The low resolution of the 20CR would severely restrict its use on its own for wind farm site-screening. We therefore perform a simple statistical calibration to link it to the higher-resolution ERA-Interim data set (ERAI), such that the adjusted 20CR data has the same wind speed distribution at each location as ERAI during their common period. Using this corrected 20CR data set, wind speeds and variability are characterised in terms of the long-term mean, standard deviation and corresponding trends. Many regions of interest show extremely weak trends on century timescales, but contain large multidecadal variability. Since reanalyses such as ERAI are often used to provide the background climatology for wind farm site assessments, but contain only a few decades of data, our results can be used as a way of incorporating decadal-scale wind climate variability into such studies, allowing investment risks for wind farms to be reduced.

  5. The universal condition: medical constructions of 'congenital phimosis' in twentieth century New Zealand and their implications for child rearing.

    Science.gov (United States)

    Watson, Lindsay R

    2014-01-01

    'Congenital phimosis' was one of a number of pseudo-pathologies that entered mainstream medicine in the nineteenth century. In the twentieth century Truby King, Henry Jellett, and Eric Corkill advocated premature foreskin retraction as the first intervention to manage 'congenital phimosis'. If that failed they recommended circumcision, although eventually it became more expedient to use circumcision exclusively. The nineteenth-century justification for such interventions was to prevent masturbation, but by the middle of the twentieth century this was replaced by prevention of infections. Gairdner's landmark paper of 1949 turned New Zealand doctors away from 'congenital phimosis' and non-therapeutic circumcision, although some doctors and persisting family traditions maintained both interventions until the end of the century.

  6. Historical occurrence and extinction of Atlantic salmon in the River Elbe from the fourteenth to the twentieth centuries

    Directory of Open Access Journals (Sweden)

    Andreska J.

    2015-03-01

    Full Text Available Data on the occurrence, biology, and historical background of the Atlantic salmon, Salmo salar L., (Pisces, Salmoniformes in the Elbe river basin (Europe, North Sea drainage area with a focus on Bohemian territory (Central Europe from the fourteenth to twentieth centuries are summarized in this paper. Historical methods of salmon fishing in Central Europe and historical legal protection of salmon in Bohemia are presented. The salmon is a model example of species which was extirpated as a result of anthropogenic changes in the landscape and rivers in some water systems. The human activities, such as stream bed regulation, dam system construction, other migration barriers, water pollution, fisheries exploitation, that led to the extirpation of Atlantic salmon in the Elbe river basin (are discussed. The last sporadic migrating native salmon were registered in the Bohemian section of the Elbe river basin in the mid twentieth century.

  7. Conference Report: Environmental Protection in the Global Twentieth Century: International Organizations, Networks and Diffusion of Ideas and Policies

    DEFF Research Database (Denmark)

    Meyer, Jan-Henrik

    Environmental Protection in the Global Twentieth Century: International Organizations, Networks and Diffusion of Ideas and Policies KFG International Conference held on 25-27 October 2012 The long rays of the yellow autumn sun shining on the red leaves of the Free University Berlin's Dahlem Campus...... provided a local touch of nature for an international conference devoted to the protection of the environment on a global scale. Sixteen researchers from eleven different countries from Europe and overseas gathered from 25 to 27 October 2012 at the Free University's Silberlaube conference centre to discuss...... "Environmental Protection in the Global Twentieth Century: International Organizations, Networks and Diffusion of Ideas and Policies". The conference was hosted and sponsored by the Research College "The Transformative Power of Europe" (jointly directed by TANJA BÖRZEL and THOMAS RISSE) at Free University's Otto...

  8. Conference Report: Environmental Protection in the Global Twentieth Century: International Organizations, Networks and Diffusion of Ideas and Policies

    DEFF Research Database (Denmark)

    Meyer, Jan-Henrik

    Environmental Protection in the Global Twentieth Century: International Organizations, Networks and Diffusion of Ideas and Policies KFG International Conference held on 25-27 October 2012 The long rays of the yellow autumn sun shining on the red leaves of the Free University Berlin's Dahlem Campus...... provided a local touch of nature for an international conference devoted to the protection of the environment on a global scale. Sixteen researchers from eleven different countries from Europe and overseas gathered from 25 to 27 October 2012 at the Free University's Silberlaube conference centre to discuss...... "Environmental Protection in the Global Twentieth Century: International Organizations, Networks and Diffusion of Ideas and Policies". The conference was hosted and sponsored by the Research College "The Transformative Power of Europe" (jointly directed by TANJA BÖRZEL and THOMAS RISSE) at Free University's Otto...

  9. Contributions to a genealogy of democracy in the twentieth century starting from the opposition Kelsen/Schmitt.

    Directory of Open Access Journals (Sweden)

    Andrés Fortunato

    2014-12-01

    Full Text Available In this work I analyze the theories of Carl Schmitt and Hans Kelsen of democracy in the light of the weberian topic of rationalization. My thesis is that this counterpoint does not escape the contemporary split that characterizes the nineteenth century modernity and continues in the twentieth century. At last, I’ll maintain that the political manifestation of this aporeticalbackground –over which one must understand the challenge of democracy– is what Schmitt calls the total State.

  10. Thermal comfort in twentieth-century architectural heritage: Two houses of Le Corbusier and André Wogenscky

    OpenAIRE

    Ignacio Requena-Ruiz

    2016-01-01

    International audience; The study of the relationship of climate and indoor thermal environments in architecture is essential to understand the inhabitants' sensory perception. This is even more relevant when working in the existing housing stock in view of the evolution of the twentieth-century heritage preservation and the problem of adapting these buildings to our current comfort and environmental criteria. The current article aims to develop a fair and balanced understanding of the approa...

  11. Lisa K. Perdigao. From Modernist Entombment to Postmodernist Exhumation Dead Bodies in Twentieth-Century American Fiction.

    Directory of Open Access Journals (Sweden)

    Ben Robbins

    2012-04-01

    Full Text Available Lisa K. Perdigao’s monograph titled From Modernist Entombment to Postmodernist Exhumation, seeks to offer a comprehensive study of the corpse as represented in American fiction of the twentieth century. Perdigao explores how novelists from a range of time periods and traditions use dead bodies as a device that is revealing of the wider formal ambitions of narrative. In her introduction, Perdigao sets out the theoretical framework on which her study is based. She draws on poststructuralist the...

  12. Antarctic station-based seasonal pressure reconstructions since 1905: 2. Variability and trends during the twentieth century

    Science.gov (United States)

    Fogt, Ryan L.; Jones, Julie M.; Goergens, Chad A.; Jones, Megan E.; Witte, Grant A.; Lee, Ming Yueng

    2016-03-01

    The Antarctic seasonal station-based pressure reconstructions evaluated in our companion paper are evaluated here to provide additional knowledge on Antarctic pressure variability during the twentieth century. In the period from 1905 to 1956, we find that the Hadley Centre gridded sea level pressure data set compared the best with our reconstructions, perhaps due to similar methods to estimate pressure without direct observations. The primary focus on the twentieth century Antarctic pressure variability was in summer and winter, as these were the seasons with the highest reconstruction skill. In summer, there is considerable interannual variability that was spatially uniform across all of Antarctica. Notable high pressure anomalies were found in the summers of 1911/1912 and 1925/1926; both summers correspond to negative phases of the Southern Annular Mode as well as El Niño events in the tropical Pacific. In addition, negative summer pressure trends during the last ~40 years across all of Antarctica are unique in the context of 30 year trends throughout the entire twentieth century, suggesting a strong component of anthropogenic forcing on the recent summer trends. In contrast, mean winter pressure is less variable from year to year during the early twentieth century, and there is less similarity between the pressure variations along the Antarctic Peninsula compared to the rest of the continent. No significant pressure trends were found consistently across all Antarctica (although some significant regional trends can be identified), and low-frequency, multidecadal-scale variability appears to dominate the historical pressure variations in this season.

  13. Writing History of Buddhist Thought in the Twentieth Century: Yinshun (1906-2005 in the Context of Chinese Buddhist Historiography

    Directory of Open Access Journals (Sweden)

    Marcus Bingenheimer

    2015-02-01

    Full Text Available Venerable Yinshun 印 順 (1906–2005 was the eminent scholar-monk in twentieth-century Chinese Buddhism. This paper is about his historiographical practice and tries to outline his position in Chinese Buddhist historiography especially in reference to the Song dynasty historian Zhipan 志磐 (thirteenth century. It tries to answer the question in what ways Yinshun can be said to have modernized Buddhist historiography for Chinese Buddhism.

  14. Some doctors of medicine who published optometry books and played significant roles in early twentieth century optometric education.

    Science.gov (United States)

    Goss, David A

    2011-01-01

    This paper provides brief profiles of four doctors of medicine who wrote books for optometrists and who were faculty members in, and/or directors of, optometry schools in the early twentieth century. Those studied were Thomas G. Atkinson (1870-1946), Marshall B. Ketchum (1856-1937), Joseph I. Pascal (1890-1955), and Clarence W. Talbot (1883-1958). The content of the books they wrote is also discussed.

  15. SUMMARY REPORT OF THE DOE DIRECT LIQUEFACTION PROCESS DEVELOPMENT CAMPAIGN OF THE LATE TWENTIETH CENTURY

    Energy Technology Data Exchange (ETDEWEB)

    F.P. Burke; S.D. Brandes; D.C. McCoy; R.A. Winschel; D. Gray; G. Tomlinson

    2001-07-01

    Following the petroleum price and supply disruptions of 1973, the U.S. government began a substantial program to fund the development of alternative fuels. Direct coal liquefaction was one of the potential routes to alternative fuels. The direct coal liquefaction program was funded at substantial levels through 1982, and at much lower levels thereafter. Those processes that were of most interest during this period were designed to produce primarily distillate fuels. By 1999, U.S. government funding for the development of direct coal liquefaction ended. Now that the end of this campaign has arrived, it is appropriate to summarize the process learnings derived from it. This report is a summary of the process learnings derived from the DOE direct coal liquefaction process development campaign of the late twentieth century. The report concentrates on those process development programs that were designed to produce primarily distillate fuels and were largely funded by DOE and its predecessors in response to the petroleum supply and price disruptions of the 1970s. The report is structured as chapters written by different authors on most of the major individual DOE-funded process development programs. The focus of the report is process learnings, as opposed to, say, fundamental coal liquefaction science or equipment design. As detailed in the overview (Chapter 2), DOE's direct coal liquefaction campaign made substantial progress in improving the process yields and the quality of the distillate product. Much of the progress was made after termination by 1983 of the major demonstration programs of the ''first generation'' (SRC-II, H-Coal, EDS) processes.

  16. Assessing the impact of vertical land motion on twentieth century global mean sea level estimates

    Science.gov (United States)

    Hamlington, B. D.; Thompson, P.; Hammond, W. C.; Blewitt, G.; Ray, R. D.

    2016-07-01

    Near-global and continuous measurements from satellite altimetry have provided accurate estimates of global mean sea level in the past two decades. Extending these estimates further into the past is a challenge using the historical tide gauge records. Not only is sampling nonuniform in both space and time, but tide gauges are also affected by vertical land motion (VLM) that creates a relative sea level change not representative of ocean variability. To allow for comparisons to the satellite altimetry estimated global mean sea level (GMSL), typically the tide gauges are corrected using glacial isostatic adjustment (GIA) models. This approach, however, does not correct other sources of VLM that remain in the tide gauge record. Here we compare Global Positioning System (GPS) VLM estimates at the tide gauge locations to VLM estimates from GIA models, and assess the influence of non-GIA-related VLM on GMSL estimates. We find that the tide gauges, on average, are experiencing positive VLM (i.e., uplift) after removing the known effect of GIA, resulting in an increase of 0.24 ± 0.08 mm yr-1 in GMSL trend estimates from 1900 to present when using GPS-based corrections. While this result is likely dependent on the subset of tide gauges used and the actual corrections used, it does suggest that non-GIA VLM plays a significant role in twentieth century estimates of GMSL. Given the relatively short GPS records used to obtain these VLM estimates, we also estimate the uncertainty in the GMSL trend that results from limited knowledge of non-GIA-related VLM.

  17. Vagabond Figures in Slovenian Visual Art and Literature at the Beginning of the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Robert Simonišek

    2011-07-01

    Full Text Available The article explores the relationship between visual and literary motifs in Slovenian painting (and illustration, graphics, and drawing and literature (both prose and poetry at the beginning of the twentieth century. It uses examples to show the popularity and rich variety of vagabond figures and their transformations and reciprocity at the level of the painting/text. However, a distinctive feature of this article is that it places the subject within the context of hermeneutics, a method that has not been used in Slovenian art history. In addition, it also reveals the symbolic complexity of the vagabond figure in the context of writers, other works, and social-historical circumstances. The emphasis is placed on artists that showed enthusiasm for this figure as a subject during the Belle Époque and also those that followed the very popular bohemian lifestyle in their everyday lives. The reception of Slovenian folk and traditional motifs from the past produced visual and semantic oscillation in which the phenomena of vagabond figures were systematized and interpreted. Many painters (e.g., Gvidon Birolla, and Maksim Gaspari and writers (e.g., Oton Župančič, Cvetko Golar, and Ivan Cankar clung to the Slovenian tradition with romantic overtones and, in line with their artistic atmosphere, integrated vagabond figures into typical Slovenian landscapes or environments. Some of them followed Symbolism and modernized the figures with autobiographical references (e.g., Fran Tratnik. The situation among the youngest generation of artists in particular showed that they managed to “escape” from copying traditional motifs and instead used them in a modern form in the “here and now” (e.g., Ivan Cankar. The discrepancy between the lack of the vagabond theme in oil painting and strong diversification in illustration, drawing, graphics, and literature could be explained by consumers’ perceived difference between “high” and “popular” art.

  18. Metal Construction Toys of the Early Twentieth Century: Their Astronomical Applications

    Science.gov (United States)

    Rumstay, K. S.

    2004-12-01

    During the early twentieth century several toy manufacturers around the globe introduced construction toys in the form of sets of metal parts which could be assembled into a variety of models. The two most successful were the Erector Set, introduced in the United States by A.C. Gilbert in 1913, and the Meccano Set, patented in 1901 in England by Frank Hornby. Whereas the Erector Set never developed beyond being a child's toy, Hornby envisioned his Meccano system as providing a way to teach principles of mechanical engineering to young schoolboys. Indeed, his sets were first marketed under the name "Mechanics Made Easy", and were endorsed by Dr. H.S. Hele-Shaw, Head of the Engineering Department at Liverpool University. Popularity of the new Meccano sets spread throughout the world, spawning the formation of numerous amateur societies composed of adolescent boys and an increasing number of adult hobbyists. The variety of parts increased during the first third of the century, and increasingly sophisticated models were constructed and exhibited in competitive events. Among these were several clocks of remarkable accuracy, and at least one equatorial mounting for a small astronomical telescope. At the same time, many university science and engineering departments found these interchangeable metal parts invaluable in the construction of experimental apparatus. In 1934 a small-scale replica of Vannevar Bush's Differential Analyzer was constructed at the University of Manchester, and used for many years to perform mathematical computations. The introduction in 1928 of a flanged ring with 73 (a sub-multiple of 365) teeth allowed for construction of accurate orreries and astronomical clocks. The most remarkable of these was the Astronomical Clock constructed in the period 1924-1932 by M. Alexandre Rahm of Paris.

  19. Air pressure effects on sea level changes during the twentieth century

    Science.gov (United States)

    Piecuch, Christopher G.; Thompson, Philip R.; Donohue, Kathleen A.

    2016-10-01

    Interpretation of tide gauge data in terms sea level (η) and ocean dynamics requires estimates of air pressure (pa) to determine the ocean's isostatic response—the inverted barometer effect (ηib). Three gridded pa products (HadSLP2, NOAA-20CRv2, and ERA-20C) are used alongside meteorological station pa and tide gauge η records to evaluate the contribution of ηib to η changes over the twentieth century. Agreement between gridded products is better during more recent periods and over regions with good historical data coverage, whereas it is worse for earlier time periods or in ocean areas with poor observational data coverage. Comparison against station data reveals the presence of systematic errors in the gridded products, for example, such that uncertainties estimated through differencing the gridded products underestimate the true errors by roughly 40% on interannual and decadal time scales. Notwithstanding such correlated errors, gridded products are still useful for interpretation of tide gauge data. Removing gridded estimates of ηib from η records reduces spatial variance in centennial trends across tide gauges by 10-30%, formal errors in centennial trends from individual gauges by ˜5%, and the temporal variance in detrended records by 10-15% on average (depending on choice of gridded product). Results here advocate for making the ηib correction to tide gauge records in studies of ocean circulation and global η over long, multidecadal, and centennial time scales using an ensemble mean taken across several gridded ηib products.

  20. Urania in the Marketplace: Astronomical Imagery in Early Twentieth-Century Advertizing

    Science.gov (United States)

    Rumstay, Kenneth S.

    2010-01-01

    The pages of popular magazines such as Sky and Telescope and Astronomy are filled with advertisements for telescopes and other equipment. However, during the past century astronomical imagery has been widely used to promote distinctly non-astronomical products and services. One of the earliest and most famous examples is the 1893 Chicago newspaper advertisement for Kirk's Soap, which was inspired by the opening of the Yerkes Observatory. A survey of popular magazines published in America during the first half of the twentieth century suggests that these advertisements fall into four categories: 1) Astronomy is universally regarded as an exact and precise science. Manufacturers of mechanical devices may employ images of telescopes or astronomers at work to suggest that their products meet these same standards of quality. This was primarily the case with makers of automobiles and automotive products, although the Longines Watch Company ran an extensive series of ads featuring observatories. 2) The heavens induce a sense of wonder in most people, and advertisers may locate their products in an a celestial setting to give them an otherworldly flavor. 3) Astronomical observatories themselves are viewed as exotic settings, and have provided backgrounds for automotive and travel ads. They may also appear in advertisements for products used in their construction. 4) Finally, newsworthy astronomical events will inspire advertisers to associate their products with that event, in order to capitalize upon the publicity. This was particularly true in the case of the 1910 passage of Halley's Comet and the 1948 opening of the 200-inch Hale telescope at Mt. Palomar. Examples of magazine advertisements from each category are presented for comparison. This work was supported by a faculty development grant from Valdosta State University.

  1. Materials for the investigation of The Seismicity Of Algeria And Adjacent Regions during the twentieth century

    Directory of Open Access Journals (Sweden)

    D. Benouar

    1994-06-01

    Full Text Available Dr. Benouar presents a full and integrated study of the recent seismicity of Algeria and adjacent regions during the twentieth century. He has amassed an impressive amount of macroseismic information pertaining to individual earthquakes, which he combines with instrumental information to reassess the origin parameters of each event. In any compilation of earthquakes it is the additional information beyond the bare accumulation of figures and facts that adds interest and social understanding to the scientific appreciation of the earthquakes themselves. For this it is necessary to know the local conditions, and Dr. Benouar brings out for us very vivid1y the differences between reporting procedures at different times this century, and the ensuing difficulties. It would be most difficult for an outsider to gather the information he presents, and he makes good use of his knowledge of his native land, as well as his professional training as an engineer. We thus learn of the reluctance of the colonial powers to report on damage or casualties outside those inflicted on the expatriate community, and the general difficulties of finding information about earthquakes that occurred during the wars of independence, at a time when effects of even major earthquakes were sometimes minor compared to those of the war itself. He also does not spare us details of political difficulties that arose during periods of reconstruction following recent earthquakes. This work is not restricted, however, to description. He examines the underlying tectonics of the area and deduces estimates of hazard and risk in various parts of the country. He then proceeds to examine the engineering consequences and discuss future needs for building codes and civil protection. Dr. Benouar has produced a work which could well form a model for those wishing to undertake comprelzensive studies of seismicity of other areas, and the measures needed to reduce the effects of catastrophic

  2. Molecular Population Genetics

    Science.gov (United States)

    Casillas, Sònia; Barbadilla, Antonio

    2017-01-01

    Molecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide sequencing era, and is currently in the era of population genomics. During this period, molecular population genetics has been revolutionized by progress in data acquisition and theoretical developments. The conceptual elegance of the neutral theory of molecular evolution or the footprint carved by natural selection on the patterns of genetic variation are two examples of the vast number of inspiring findings of population genetics research. Since the inception of the field, Drosophila has been the prominent model species: molecular variation in populations was first described in Drosophila and most of the population genetics hypotheses were tested in Drosophila species. In this review, we describe the main concepts, methods, and landmarks of molecular population genetics, using the Drosophila model as a reference. We describe the different genetic data sets made available by advances in molecular technologies, and the theoretical developments fostered by these data. Finally, we review the results and new insights provided by the population genomics approach, and conclude by enumerating challenges and new lines of inquiry posed by increasingly large population scale sequence data. PMID:28270526

  3. Molecular Population Genetics.

    Science.gov (United States)

    Casillas, Sònia; Barbadilla, Antonio

    2017-03-01

    Molecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide sequencing era, and is currently in the era of population genomics. During this period, molecular population genetics has been revolutionized by progress in data acquisition and theoretical developments. The conceptual elegance of the neutral theory of molecular evolution or the footprint carved by natural selection on the patterns of genetic variation are two examples of the vast number of inspiring findings of population genetics research. Since the inception of the field, Drosophila has been the prominent model species: molecular variation in populations was first described in Drosophila and most of the population genetics hypotheses were tested in Drosophila species. In this review, we describe the main concepts, methods, and landmarks of molecular population genetics, using the Drosophila model as a reference. We describe the different genetic data sets made available by advances in molecular technologies, and the theoretical developments fostered by these data. Finally, we review the results and new insights provided by the population genomics approach, and conclude by enumerating challenges and new lines of inquiry posed by increasingly large population scale sequence data. Copyright © 2017 Casillas and Barbadilla.

  4. [Bibliometry of biological systematics in Latin America during the twentieth century in three global databases].

    Science.gov (United States)

    Michán, Layla; Llorente-Bousquets, Jorge

    2010-06-01

    We present a review of the biological systematic research in Latin America during the twentieth century, applying a bibliometric analysis to the information contained in international databases with the largest number of biological records: Biosis (since 1969), CAB (since 1910) and Science Citation Index (since 1900), to recognize certain patterns and trends regarding the document production. We obtained 19079 documents and 1387 journals for Biosis, 14326 and 2537 for CAB, 3257 and 1636 for SCI. Of the documents, 54.6% related to new species, 15.3% dealt with morphology, 14.9% keys, 12.5% descriptions, 10.6% cases of synonymies, 6% new genera, 4.9% new geographical records, 23.6% geographical distribution, 4.2% redescriptions, and 3.6% with new nomenclatural combinations. The regions mentioned were South America with 11.9%, Central America with 4% and America (all) with 2.56%. Nineteen Latin American countries appear, whereas outside this region we found the United States of America with 12.6% of representation and Canada with 3%. Animals (65.6%) were the most studied taxa, which was 1.7 times higher than what was published for plants (37%), 11 times higher than fungi (6%) and nearly 30 times higher than microorganisms (2.3%). Out of the 155 journals that produced 66% of the papers, 76.5% were better represented in Biosis, 21.4% in CAB and 2% in SCI. Twenty-nine journals published 33% of the articles, the maximum number of records obtained was 69% for Biosis, CAB 24% and 6.9% for SCI, three (10.3%) are in biology, 11 (37.9%) in botany, 13 (44.8%) zoology, and two (6.9%) paleontology; eight of these journals (27.5%) were published in Latin America and twenty were indexed in the Science Citation Index. In the last two years more journals of the region that publish on taxonomy have been indexed, but their impact factor is still low. However, the impact factor of a number of Latin American journals that published biodiversity increased with time. Countries that are

  5. Forced and Unforced Variability of Twentieth Century North American Droughts and Pluvials

    Science.gov (United States)

    Cook, Benjamin I.; Cook, Edward R.; Anchukaitis, Kevin J.; Seager, Richard; Miller, Ron L.

    2010-01-01

    Research on the forcing of drought and pluvial events over North America is dominated by general circulation model experiments that often have operational limitations (e.g., computational expense, ability to simulate relevant processes, etc). We use a statistically based modeling approach to investigate sea surface temperature (SST) forcing of the twentieth century pluvial (1905-1917) and drought (1932-1939, 1948-1957, 1998-2002) events. A principal component (PC) analysis of Palmer Drought Severity Index (PDSI) from the North American Drought Atlas separates the drought variability into five leading modes accounting for 62% of the underlying variance. Over the full period spanning these events (1900-2005), the first three PCs significantly correlate with SSTs in the equatorial Pacific (PC 1), North Pacific (PC 2), and North Atlantic (PC 3), with spatial patterns (as defined by the empirical orthogonal functions) consistent with our understanding of North American drought responses to SST forcing. We use a large ensemble statistical modeling approach to determine how successfully we can reproduce these drought/pluvial events using these three modes of variability. Using Pacific forcing only (PCs 1-2), we are able to reproduce the 1948-1957 drought and 1905-1917 pluvial above a 95% random noise threshold in over 90% of the ensemble members; the addition of Atlantic forcing (PCs 1-2-3) provides only marginal improvement. For the 1998-2002 drought, Pacific forcing reproduces the drought above noise in over 65% of the ensemble members, with the addition of Atlantic forcing increasing the number passing to over 80%. The severity of the drought, however, is underestimated in the ensemble median, suggesting this drought intensity can only be achieved through internal variability or other processes. Pacific only forcing does a poor job of reproducing the 1932-1939 drought pattern in the ensemble median, and less than one third of ensemble members exceed the noise threshold

  6. The Strategic Petroleum Reserve: United States energy security, oil politics, and petroleum reserves policies in the twentieth century

    Science.gov (United States)

    Beaubouef, Bruce Andre

    The history of U.S. petroleum reserves policies in the twentieth century, including the Strategic Petroleum Reserve (SPR) program, provides a case study of the economic and political aspects of national security, and shows the ways in which the American political economy influences national security. One key problem plagued federal petroleum reserve programs and proposals throughout the twentieth century. In a political economy which traditionally placed strong emphasis upon the sanctity of private property and free markets, could the government develop an emergency petroleum reserve policy despite opposition from the private sector? Previous literature on the SPR and oil-stockpiling programs has largely disregarded the historical perspective, focusing instead upon econometric models, suggesting future oil-stockpiling policy options. This study will also make conclusions about the future of governmental oil-stockpiling policies, particularly with regard to the SPR program, but it will do so informed by a systematic history of the emergency petroleum reserve impulse in the twentieth century. Through a study of the emergency petroleum reserve impulse, one can see how the American political economy of oil and energy changed over the twentieth century. As petroleum became crucial to the military and then economic security of the United States, the federal government sought to develop emergency petroleum reserves first for the military, then for the civilian economy. But while the American petroleum industry could deliver the energy "goods" to American energy consumers at a reasonable price, the companies reigned supreme in the political equation. While that was true, federal petroleum reserve programs and proposals conflicted with and were overwhelmed by the historic American tradition of individual economic and private property rights. The depletion of American petroleum reserves changed that political equation, and the ensuing energy crises of the 1970s not only

  7. Maintaining Masculinity in Mid-Twentieth-Century American Psychology: Edwin Boring, Scientific Eminence, and the "Woman Problem".

    Science.gov (United States)

    Rutherford, Alexandra

    2015-01-01

    Using mid-twentieth-century American psychology as my focus, I explore how scientific psychology was constructed as a distinctly masculine enterprise and was navigated by those who did not conform easily to this masculine ideal. I show how women emerged as problems for science through the vigorous gatekeeping activities and personal and professional writings of disciplinary figurehead Edwin G. Boring. I trace Boring's intellectual and professional socialization into masculine science and his efforts to understand women's apparent lack of scientific eminence, efforts that were clearly undergirded by preexisting and widely shared assumptions about men's and women's capacities and preferences.

  8. Balkans as a cultural symbol in the Serbian music of the first half of the twentieth century

    Directory of Open Access Journals (Sweden)

    Milanović Biljana

    2008-01-01

    Full Text Available Focus on the internalization of Western images in the Balkans has special significance in researching Serbian art. The functioning of Balkanism as it overlapped and intersected with Orientalism is indicated in the text by an examination of the cases of Petar Konjović, Miloje Milojević and Josip Slavenski, the three significant composers working in Serbia during the first half of the twentieth century. Their modernistic projects present different metaphors of the Balkans. Nevertheless each of them is marked by desire to change the Balkan image into a 'positive' one and thus stands as a special voice for Serbian and regional placing in European competition for musical spaces.

  9. The return of the phoenix: the 1963 International Congress of Zoology and American zoologists in the twentieth century.

    Science.gov (United States)

    Johnson, Kristin

    2009-01-01

    This paper examines the International Congress of Zoology held in Washington D.C. in 1963 as a portrait of American zoologists' search for effective and rewarding relationships with both each other and the public. Organizers of the congress envisioned the congress as a last ditch effort to unify the disparate subdisciplines of zoology, overcome the barriers of specialization, and ward off the heady claims of more reductionist biologists. The problems zoologists faced as they worked to fulfill these ambitious goals illuminate some of the challenges faced by members of the naturalist tradition as they worked to establish disciplinary unity while seeking public support in the competitive world of twentieth century science.

  10. Salamanca’s theater and musical activity in the first quarter of twentieth century through the local press

    Directory of Open Access Journals (Sweden)

    Francisco José Álvarez García

    2011-06-01

    Full Text Available The theaters at the beginning of twentieth century are one of the main focuses in which condenses the musician-artistic activity of small and large Spanish cities. Salamanca could not be less and in the three capitals theaters “Liceo”, “Bretón” and “Moderno” we find a very rich musical activity like Zarzuelas, Concerts, Lyric Theatre, Tunas, etc., which will make to Salamanca the most important center of the music scene in the province until almost the Second Spanish Republic.

  11. Science and miscegenation in the early twentieth century: Edgard Roquette-Pinto's debates and controversies with US physical anthropology.

    Science.gov (United States)

    Souza, Vanderlei Sebastião de

    2016-01-01

    The article analyzes Brazilian anthropologist Edgard Roquette-Pinto's participation in the international debate that involved the field of physical anthropology and discussions on miscegenation in the first decades of the twentieth century. Special focus is on his readings and interpretations of a group of US anthropologists and eugenicists and his controversies with them, including Charles Davenport, Madison Grant, and Franz Boas. The article explores the various ways in which Roquette-Pinto interpreted and incorporated their ideas and how his anthropological interpretations took on new meanings when they moved beyond Brazil's borders.

  12. [The medical, social and institutional challenges resulting from poliomyelitis: comprehensive rehabilitation in Argentina in the mid-twentieth century].

    Science.gov (United States)

    Alvarez, Adriana

    2015-01-01

    Poliomyelitis on an epidemic scale gave rise to several challenges, one of which was the rehabilitation from the after-effects on many of the people who suffered from the disease. Paralysis and the ways it transformed the concept of physical rehabilitation (where the objective was only to restore the mobility of the affected muscles) and comprehensive rehabilitation that included social, educational and professional aspects in Argentina in the mid-twentieth century are the themes addressed in this article. It uses the methodology of institutional history that interacts in an ongoing manner with the history of health and disease.

  13. Family Life in Europe in the Twentieth Century/ Życie rodzinne w Europie w XX wieku

    Directory of Open Access Journals (Sweden)

    MARIE MAREČKOVÁ

    2012-01-01

    Full Text Available Family life in Europe has undergone many changes in the twentieth century. These include the lifestyle of women, their legal freedom, family relations, relations with partners, relations with the older generation, and relations with children. The position of women in society has also undergone many transformations. Problems remain, however, in the social and family policy of the state, as women engaged in the working process give preference to their own plans and their need for self-fulfi lment. The main goal of state family policy in the twenty-first century is, then, to ensure a harmonious balance between professional activity and family life.

  14. Family ties and intergenerational relationships in European families in the twentieth century/ Wi ę zy rodzinne i relacje mi ę dzypokoleniowe w rodzinach europejskich w XX wieku

    Directory of Open Access Journals (Sweden)

    MARIE MAREČKOVÁ

    2014-01-01

    Full Text Available Intergenerational family relationships still performed an important social function in rural society in Europe at the beginning of the twentieth century. The situation within the Czech family illustrates the current problems in family ties and intergenerational relationships that have surfaced since the nineteen nineties. Negative developmental trends are being seen, particularly in comparison with family circumstances in other European countries, most significantly the continuing ageing of the population and the wide-ranging activities of senior s. Looser relationships with their families and a decline in their engagement in caring for their grandchildren mean that Czech grandparents tend to rank alongside more socially develope d countries in this respect. Under Czech conditions, however, this can lead to great strain on the active roles played by seniors. The growing number of adult offspring, particularly men, living with their parents is a far from progressive trend in social and economic development, and corresponds more closely with southern European traditions. A preference for alternative forms of cohabitation, particularly among partners with primary education, the postponing of the birth of the first child, the growth in the number of single-person households and, perhaps most importantly, the enormous rise in the number of households comprised of young or middle-aged individuals in the economically productive age group may, it is true, rank the Czech Republic among socially developed countries and at around the European average, though in view of the unfavourable demographic trend a fundamental change in state support for marriage and the family is, however, also essential in the Czech Republic. The fact is that more than a third of families with children are threatened with poverty. The conclusion arising from the analyses performed indicate that the current problems in state social and family policy are reflected in the increasing

  15. Probabilistic precipitation and temperature downscaling of the Twentieth Century Reanalysis over France

    Science.gov (United States)

    Caillouet, Laurie; Vidal, Jean-Philippe; Sauquet, Eric; Graff, Benjamin

    2015-04-01

    considered to correct monthly precipitation and temperature time series. The first one applies two new analogy steps, using the sea surface temperature (SST) and the large-scale two-meter temperature. The second method is a calendar selection that keeps the closest analogue dates in the year for each target date. A sensitivity study has been performed to assess the final number of analogues dates to retain for each method. A comparison to Safran over 1958-2010 shows that biases on the interannual cycle of precipitation and temperature are strongly reduced with both methods. Using two supplementary analogy levels moreover leads to a large improvement of correlation in seasonal temperature time series. These two methods have also been validated before 1958 thanks to both raw observations and homogenized time series. The two post-processing methods come with some advantages and drawbacks. The calendar selection allows to slightly better correct for seasonal biases in precipitation and is therefore adapted in a forecasting context. The selection with two supplementary analogy levels would allow for possible season shifts and SST trends and is therefore better suited for climate reconstruction and climate change studies. Compo, G. P. et al. (2011). The Twentieth Century Reanalysis Project. Quarterly Journal of the Royal Meteorological Society, 137:1-28. doi: 10.1002/qj.776 Radanovics, S., Vidal, J.-P., Sauquet, E., Ben Daoud, A., and Bontron, G. (2013). Optimising predictor domains for spatially coherent precipitation downscaling. Hydrology and Earth System Sciences, 17:4189-4208. doi:10.5194/hess-17-4189-2013 Vidal, J.-P ., Martin, E., Franchistéguy, L., Baillon, M., and Soubeyroux, J.-M. (2010). A 50-year high-resolution atmospheric reanalysis over France with the Safran system. International Journal of Climatology, 30:1627-1644. doi:10.1002/joc.2003

  16. The Lover with a Long Neck: The Motif of Leda and the Swan in Twentieth-Century Slovenian Painting

    Directory of Open Access Journals (Sweden)

    Dejan Prša

    2011-07-01

    Full Text Available This article presents the thesis that the motif of Leda and the Swan, which had a remarkable impact on the arts in the modern era (especially in the period between the Renaissance and the end of the twentieth century, represents one of the most significant Ancient motifs in twentieth-century Slovenian painting. Comparing works of fine arts with European models, comparative research on Slovenian artists’ works, and motif analysis disclose reasons for its popularity in Slovenian ethnic territory and reveal both the stereotyped and original content and the messages incorporated into the motif. Not only have some of the most eminent figures in Slovenian painting (e.g., Jožef Tominc, Anton Ažbe, France Kralj, Stojan Batič, Metka Krašovec, Rudi Španzel, and Marko Jakše dedicated themselves to the motif, but the creations of numerous lesser-known artists (e.g., Samo Kralj, Jože Meglič, and Marina Bahovec have also been particularly influenced by the motif of Leda and the Swan.

  17. Relationship between sunshine duration and temperature trends across Europe since the second half of the twentieth century

    Science.gov (United States)

    Besselaar, E. J. M.; Sanchez-Lorenzo, A.; Wild, M.; Klein Tank, A. M. G.; Laat, A. T. J.

    2015-10-01

    Global radiation is a fundamental source of energy in the climate system. A significant impact of global radiation on temperature change is expected due to the widespread dimming/brightening phenomenon observed since the second half of the twentieth century. This work describes the analysis of 312 stations with sunshine duration (SD) series, a proxy for global radiation, and temperature series in the European Climate Assessment & Dataset (ECA&D) with data over the period 1961-2010. The relationship between SD and temperature series is analyzed for four temperature variables: maximum (Tmax), minimum (Tmin), mean temperature (Tmean), and diurnal temperature range (DTR). The analyses are performed on annual and seasonal basis. The results show strong positive correlations between SD and temperatures over Europe, with highest correlation for DTR and Tmax during the summer period. These results confirm the strong relationship between SD and temperature trends over Europe since the second half of the twentieth century. This study supports previous suggestions that dimming (brightening) has partially decreased (increased) temperatures thereby modulating the greenhouse gas induced warming rates over Europe.

  18. An assemblage of science and home. The gendered lifestyle of Svante Arrhenius and early twentieth-century physical chemistry.

    Science.gov (United States)

    Bergwik, Staffan

    2014-06-01

    This essay explores the gendered lifestyle of early twentieth-century physics and chemistry and shows how that way of life was produced through linking science and home. In 1905, the Swedish physical chemist Svante Arrhenius married Maja Johansson and established a scientific household at the Nobel Institute for Physical Chemistry in Stockholm. He created a productive context for research in which ideas about marriage and family were pivotal. He also socialized in similar scientific sites abroad. This essay displays how scholars in the international community circulated the gendered lifestyle through frequent travel and by reproducing gendered behavior. Everywhere, husbands and wives were expected to perform distinct duties. Shared performances created loyalties across national divides. The essay thus situates the physical sciences at the turn of the twentieth century in a bourgeois gender ideology. Moreover, it argues that the gendered lifestyle was not external to knowledge making but, rather, foundational to laboratory life. A legitimate and culturally intelligible lifestyle produced the trust and support needed for collaboration. In addition, it enabled access to prestigious facilities for Svante Arrhenius, ultimately securing his position in international physical chemistry.

  19. Anomalous mid-twentieth century atmospheric circulation change over the South Atlantic compared to the last 6000 years

    Science.gov (United States)

    Turney, Chris S. M.; Jones, Richard T.; Lister, David; Jones, Phil; Williams, Alan N.; Hogg, Alan; Thomas, Zoë A.; Compo, Gilbert P.; Yin, Xungang; Fogwill, Christopher J.; Palmer, Jonathan; Colwell, Steve; Allan, Rob; Visbeck, Martin

    2016-06-01

    Determining the timing and impact of anthropogenic climate change in data-sparse regions is a considerable challenge. Arguably, nowhere is this more difficult than the Antarctic Peninsula and the subantarctic South Atlantic where observational records are relatively short but where high rates of warming have been experienced since records began. Here we interrogate recently developed monthly-resolved observational datasets from the Falkland Islands and South Georgia, and extend the records back using climate-sensitive peat growth over the past 6000 years. Investigating the subantarctic climate data with ERA-Interim and Twentieth Century Reanalysis, we find that a stepped increase in precipitation across the 1940s is related to a change in synoptic atmospheric circulation: a westward migration of quasi-permanent positive pressure anomalies in the South Atlantic has brought the subantarctic islands under the increased influence of meridional airflow associated with the Amundsen Sea Low. Analysis of three comprehensively multi-dated (using 14C and 137Cs) peat sequences across the two islands demonstrates unprecedented growth rates since the mid-twentieth century relative to the last 6000 years. Comparison to observational and reconstructed sea surface temperatures suggests this change is linked to a warming tropical Pacific Ocean. Our results imply ‘modern’ South Atlantic atmospheric circulation has not been under this configuration for millennia.

  20. Has psychology "found its true path"? Methods, objectivity, and cries of "crisis" in early twentieth-century French psychology.

    Science.gov (United States)

    Carson, John

    2012-06-01

    This article explores how French psychologists understood the state of their field during the first quarter of the twentieth century, and whether they thought it was in crisis. The article begins with the Russian-born psychologist Nicolas Kostyleff and his announcement in 1911 that experimental psychology was facing a crisis. After briefly situating Kostyleff, the article examines his analysis of the troubles facing experimental psychology and his proposed solution, as well as the rather muted response his diagnosis received from the French psychological community. The optimism about the field evident in many of the accounts surveying French psychology during the early twentieth century notwithstanding, a few others did join Kostyleff in declaring that all was not well with experimental psychology. Together their pronouncements suggest that under the surface, important unresolved issues faced the French psychological community. Two are singled out: What was the proper methodology for psychology as a positive science? And what kinds of practices could claim to be objective, and in what sense? The article concludes by examining what these anxieties reveal about the type of science that French psychologists hoped to pursue. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. A Comparative Study: Self-Realization in Twentieth-Century Western Thought, Ibn e Arabi's Idea, and Theatre of The Absurd

    Directory of Open Access Journals (Sweden)

    Bahee Hadaegh

    2011-01-01

    Full Text Available Following humans' struggles to achieve a better under¬standing of the self throughout major historical periods, the idea of the quest for a whole self is once more rekindled in the anxiety-laden atmosphere of the twentieth century. However, unlike the previous approaches, the twentieth century reflection of the notion of the quest for self-realization is paradoxically revealed in a new model of struggle which inclines more toward spiritual search. This inward struggle manifests itself through connecting the ego to the unconscious world, in line with the theories of Freud and Jung. The similarity which exists between Jung's psychic state and the Sufis' mystical world defined by Ibn e Arabi, makes it possible to reconsider the seemingly nihilist readings of the quest for self-realization of the twentieth century absurd thoughts in a positive way

  2. Twentieth century temperature trends in CMIP3, CMIP5, and CESM-LE climate simulations: Spatial-temporal uncertainties, differences, and their potential sources

    Science.gov (United States)

    Kumar, Sanjiv; Kinter, James L.; Pan, Zaitao; Sheffield, Justin

    2016-08-01

    The twentieth century climate simulations from the Coupled Model Intercomparison Project Phase 3 (CMIP3) and Phase 5 (CMIP5) are compared to assess the models' ability to capture observed near-surface air temperature trends at global, continental, and regional scales. We computed trends by using a nonparametric method and considering long-term persistence in the time series. The role of internal variability is examined by using large ensemble climate simulations from the National Center for Atmospheric Research model Community Earth System Model (CESM). We computed temperature trends for three periods: the twentieth century, the second half of the twentieth century, and (3) the recent hiatus period to contrast the roles of external forcing and internal variability at various spatial and temporal scales. Both CMIP ensembles show statistically significant warming at global and continental scales during the twentieth century. We found a small but statistically significant difference between CMIP3 (0.57 ± 0.07 °C/century) and CMIP5 (0.47 ± 0.06 °C/century) twentieth century temperature trends, with the CMIP3 estimate being closer to the observations. The spatial structure of long-term temperature trends, and top-of-the atmosphere net radiation trends, suggests that differences in model parameterizations and feedback processes that lead to a smaller net radiative forcing are likely contributing to the differences between CMIP3 and CMIP5. The estimate of internal variability based on the CESM large ensemble spans 24% of the uncertainty in CMIP5 for the twentieth century temperature trends, and 76% for the recent hiatus period, both at global scales, and 43% and almost 100% during the corresponding time periods at regional scales.

  3. [The motives for hospitalization at Adauto Botelho Hospital (Cariacica, ES) in the second half of the twentieth century].

    Science.gov (United States)

    Carrion, Carla Torres Pereira; Margotto, Lilian Rose; Aragão, Elizabeth Maria Andrade

    2014-01-01

    This paper discusses the procedures for referring patients to Adauto Botelho Hospital, in Cariacica, Espírito Santo state, Brazil. The research is based on the medical records since its inauguration in 1954 and statements by people who worked there in the second half of the twentieth century. One hundred and two records were analyzed and four people were interviewed. The records revealed the active involvement of the Chief of Police in hospitalizations. The interviews corroborate this, while also showing the long duration of the hospitalizations. The tone of the paper is set by the life stories of the people hospitalized there. The conclusion is that this hospital served not so much for treatment as for confinement.

  4. Where Now the Harp? Listening for the Sounds of Old English Verse, from Beowulf to the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Chris Jones

    2009-10-01

    Full Text Available This essay examines the representation or staging of oral performance and poetic composition within _Beowulf_, in order to argue that poem thematizes and mythologizes its own origins, and is as much interested in recovering the sounds of oral performances that pre-date its own manuscript inscription as modern Anglo-Saxon scholarship has been. The second half of the essay considers the recovery and reimagining of an Anglo-Saxon “soundscape” in the work of two twentieth-century poets, W. S. Graham and Edwin Morgan. The invocation of this “Saxonesque” patterning of sound invokes or triggers a historically constituted set of associations with the whole body of Old English poetry; that is, an allusion to a corpus, rather than to a specific text, is made through sound patterning.

  5. Between the national and the universal: natural history networks in Latin America in the nineteenth and twentieth centuries.

    Science.gov (United States)

    Duarte, Regina Horta

    2013-12-01

    This essay examines contemporary Latin American historical writing about natural history from the nineteenth through the twentieth centuries. Natural history is a "network science," woven out of connections and communications between diverse people and centers of scholarship, all against a backdrop of complex political and economic changes. Latin American naturalists navigated a tension between promoting national science and participating in "universal" science. These tensions between the national and the universal have also been reflected in historical writing on Latin America. Since the 1980s, narratives that recognize Latin Americans' active role have become more notable within the renewal of the history of Latin American science. However, the nationalist slant of these approaches has kept Latin American historiography on the margins. The networked nature of natural history and Latin America's active role in it afford an opportunity to end the historiographic isolation of Latin America and situate it within world history.

  6. Development of Accounting Theories Specific to the National Accounting Literature of the First Half of Twentieth Century

    Directory of Open Access Journals (Sweden)

    Sorin Damian

    2011-05-01

    Full Text Available Need to identify plausible explanations of the principles underlying the double entry accountingover time determined by various manifestations of thought that have resulted in many theories. All thesetheories have proposed to explain and substantiate dopic formalism, but many of them no longer a valuetoday than a purely historical perspective. The representative of such theories has been many pages writtenRomanian and foreign authors in the first half of the twentieth century. Some Romanian authors mention theIoan E. Evian, D. Voina, CG Demetrescu, S. Iacobescu, Al. Sorescu, C. Pantu, C. Petrescu, Grigore-TrancuIaşi and others. Bibliography time accounting theories shared accounts: embryos of theories and scientifictheories.

  7. Freedom to divorce or protection of marriage? The divorce laws in Denmark, Norway, and Sweden in the early twentieth century.

    Science.gov (United States)

    Le Bouteillec, Nathalie; Bersbo, Zara; Festy, Patrick

    2011-01-01

    In the period 1909-1927, new laws concerning divorce and marriage were enacted by the Scandinavian countries. Both at the time and more recently, these laws were considered as "liberal" as they promoted greater freedom to divorce based on individuality and gender equality. In this article, the authors first analyze the changes in these Family laws in the early twentieth century. Then, the authors study the effect of these laws on divorce and marriage patterns. As these laws did not modify the trend in divorce rates, the authors ask why this was the case. The authors' conclusions are that the laws were more concerned with preserving the sanctity of marriage and maintaining social order than with promoting individual freedom and gender equality.

  8. Planning ideology and geographic thought in the early twentieth century: Charles Whitnall's progressive era park designs for socialist Milwaukee.

    Science.gov (United States)

    Platt, Lorne A

    2010-01-01

    As Milwaukee’s chief park planner in the early to mid-twentieth century, Charles Whitnall responded to the various underlying ideologies of the period within which he worked. His preference for parks was a political and physical response to and remedy for the industrialized and heavily congested city he called home. By examining the Progressive Era discourse associated with planning, this article situates Whitnall’s work within the political, aesthetic, and environmental contexts of geographic thought that influenced his plans for Milwaukee. In promoting a physical awareness associated with the natural features of the region and responding to the sociopolitical framework of contemporaries such as Ebenezer Howard, Whitnall incorporated a sense of compassion within his planning. He responded to the preexisting beer gardens of Pabst and Schlitz, as well as Olmsted-designed park spaces, by advocating for decentralization as part of a broader socialist agenda that had swept through Milwaukee during the early 1900s.

  9. Norman Mailer - the most influental critic of contemporary reality in the second half of the twentieth century

    Directory of Open Access Journals (Sweden)

    Jasna Potočnik Topler

    2013-12-01

    Full Text Available Norman Mailer, one of the most influential authors of the second half of the twentieth century, faithfully followed his principle that a writer should alsobe a critic of contemporary reality. Therefore, most of his works portray the reality of the United States of America and the complexities of the contemporary American scene. Mailer described the spirit of his time - from the terror of war and numerous dynamic social and political processes to the 1969 moon landing. Conflicts were often in the centre of his writing, as was the relationship between an individual and the society; he speaks of politicalpower and the dangerous power of capital, while pointing to the threat of totalitarianism in America. Mailer spent his entire career writing about violence, power, perverted sexuality, the phenomenon of Hitler, terrorism, religion and corruption. He continually pointed out that individuals were in constant danger of losing freedom and dignity.

  10. Faszination einer Kindsmörderin. Medea im 20. Jahrhundert Fascinated by a Child Murderer. Medea in the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Barbara Feichtinger

    2007-03-01

    Full Text Available Die Berliner Literaturwissenschaftlerin Inge Stephan interpretiert ein beeindruckendes Panorama von Medea-Bearbeitungen in Literatur, bildender Kunst, Film und Musik. Sie spürt in ihrem Buch zur Medea-Rezeption im 20. Jh. in höchst differenzierter und anregender Weise den vielfältigen künstlerischen Auseinandersetzungen der Moderne mit einer in vieler Hinsicht provozierenden Frauengestalt der Antike nach.The Berlin-based literary scholar Inge Stephan interprets an impressive panorama of the treatments of Medea in literature, the visual arts, film, and music. In her book on Medea reception in the twentieth century, Stephan traces the numerous modern artistic approaches to this quite provocative female figure of antiquity in a highly differentiated and thought-provoking manner.

  11. Disputes over Philosophical Views in the First Half of the Twentieth Century and Development of Contemporary Chinese Philosophy

    Institute of Scientific and Technical Information of China (English)

    Sun Zhengyu

    2006-01-01

    To explore the development of contemporary Chinese philosophy,fundamentally,is to explore the development of Marxist philosophy in contemporary China.The disputes over philosophical views in Chinese academic circles during the first half of the twentieth century have been focused on understanding Marxist philosophy from such aspects as "what kind of philosophy Chinese society needs," "the relation of philosophy to science," and "philosophy as an idea to reflect on one's life." These explorations have provided us a significant ideological insight into the development of Marxist philosophy and contemporary Chinese philosophy;that is,in contemporary China,Marxist philosophy,as a doctrine of the liberation and all-round development of human beings,exists not only as a kind of"doctrine"or "academy" but also as a kind of widely accepted "xueyuan (academic cultivations)"among people.

  12. Sound Objects and Sound Products: Standardizing a New Culture of Listening in the First Half of the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Alexandra Hui

    2012-12-01

    Full Text Available In this chapter I develop the psychological underpinnings of environmental music towards an understanding of how the goals of cognitive and behavioral psycholo-gists contributed to a new kind of listening at the beginning of the twentieth century. I begin with an examination of nineteenth-century concerns about both the physical and psychological effects of music and fraught debate among experi-mental psychologists of the role of musical expertise in the laboratory. These con-cerns were, I argue, rooted in the assumption of a direct, corporeal connection between the generation and reception of music, usually bound within a single, individual body. In the twentieth century, new technology liberated the listener from a temporally- and geographically-bound experience of music. The Tone Tests, Re-Creation Recitals, and Mood Change “parties” of Thomas Edison and the psychologist Walter Bingham show that recording technology allowed for a normalization and standardization of listening not previously possible in the music halls and laboratories of the nineteenth century. Rather paradoxically, since it also made music more accessible to the individual listener, recorded music, mobilized by industrial psychologists and record companies alike, created a new sound experience actively designed for the lowest common denominator of mass listen-ing. It also contributed to the cultivation of a new practice of mass listening. The new mass listening practice presents broader questions about the definition of music and its functional role – If the function of music is to be ignored, is it still music?

  13. Unprecedented low twentieth century winter sea ice extent in the Western Nordic Seas since A.D. 1200

    Energy Technology Data Exchange (ETDEWEB)

    Macias Fauria, M. [University of Calgary, Biogeoscience Institute, Calgary, AB (Canada); University of Helsinki, Department of Geology, Helsinki (Finland); Finnish Forest Institute, Rovaniemi Research Station, Rovaniemi (Finland); University of Barcelona, Department of Ecology, Faculty of Biology, Barcelona (Spain); Grinsted, A. [University of Copenhagen, Centre for Ice and Climate, Niels Bohr Institute, Copenhagen (Denmark); University of Lapland, Arctic Centre, Rovaniemi (Finland); Helama, S.; Eronen, M. [University of Helsinki, Department of Geology, Helsinki (Finland); Moore, J. [University of Copenhagen, Centre for Ice and Climate, Niels Bohr Institute, Copenhagen (Denmark); University of Oulu, Thule Institute, Oulu (Finland); Beijing Normal University, College of Global Change and Earth System Science, Beijing (China); Timonen, M. [Finnish Forest Institute, Rovaniemi Research Station, Rovaniemi (Finland); Martma, T. [Tallinn University of Technology, Institute of Geology, Tallinn (Estonia); Isaksson, E. [Norwegian Polar Institute, Polar Environmental Centre, Tromsoe (Norway)

    2010-05-15

    We reconstructed decadal to centennial variability of maximum sea ice extent in the Western Nordic Seas for A.D. 1200-1997 using a combination of a regional tree-ring chronology from the timberline area in Fennoscandia and {delta}{sup 18}O from the Lomonosovfonna ice core in Svalbard. The reconstruction successfully explained 59% of the variance in sea ice extent based on the calibration period 1864-1997. The significance of the reconstruction statistics (reduction of error, coefficient of efficiency) is computed for the first time against a realistic noise background. The twentieth century sustained the lowest sea ice extent values since A.D. 1200: low sea ice extent also occurred before (mid-seventeenth and mid-eighteenth centuries, early fifteenth and late thirteenth centuries), but these periods were in no case as persistent as in the twentieth century. Largest sea ice extent values occurred from the seventeenth to the nineteenth centuries, during the Little Ice Age (LIA), with relatively smaller sea ice-covered area during the sixteenth century. Moderate sea ice extent occurred during thirteenth-fifteenth centuries. Reconstructed sea ice extent variability is dominated by decadal oscillations, frequently associated with decadal components of the North Atlantic Oscillation/Arctic Oscillation (NAO/AO), and multi-decadal lower frequency oscillations operating at {proportional_to}50-120 year. Sea ice extent and NAO showed a non-stationary relationship during the observational period. The present low sea ice extent is unique over the last 800 years, and results from a decline started in late-nineteenth century after the LIA. (orig.)

  14. O comunismo na história do século XX Communism in the Twentieth-Century history

    Directory of Open Access Journals (Sweden)

    Bruno Groppo

    2008-01-01

    Full Text Available O comunismo do século XX teve, desde seu início, uma dimensão dupla: o movimento revolucionário, por um lado; o sistema de poder estatal, por outro. Os dois aspectos são indissociáveis. A história do comunismo como movimento revolucionário em escala mundial está estreitamente ligada à história da Rússia e, em seguida, à da União Soviética. E o sistema soviético, na configuração definitiva que lhe foi impressa pelo stalinismo, foi ao longo de muitas décadas o modelo de referência para o conjunto do mundo comunista. Em outras palavras, o comunismo do século XX identifica-se primordialmente com a experiência histórica do poder soviético. Os demais comunismos, heréticos ou dissidentes em relação à ortodoxia stalinista, desempenharam um papel menos importante, freqüentemente marginal.Twentieth-century communism had, since the beginning, a double dimension: the revolutionary movement, on the one hand; the state power system, on the other. Both sides are inseparable. The history of communism as a revolutionary movement in world scale is intimately linked to the Russian and then Soviet history. And the Soviet system, in the final configuration stalinism gave to it, was a model to the whole communist world along many decades. So that twentieth-century communism is primordially identical with the historical experience of the Soviet power. Other brands of communism, heretical or dissident to Stalinist ortodoxy, performed a less important, often marginal, role.

  15. Against the Science-Religion Conflict: The Genesis of a Calvinist Science Faculty in the Netherlands in the Early Twentieth Century

    Science.gov (United States)

    Flipse, Abraham C.

    2008-01-01

    This paper gives an account of the establishment and expansion of a Faculty of Science at the Calvinist "Free University" in the Netherlands in the 1930s. It describes the efforts of a group of orthodox Christians to come to terms with the natural sciences in the early twentieth century. The statutes of the university, which had been…

  16. 'Poisoned History': A Comparative Study of Nationalism, Propaganda and the Treatment of War and Peace in the Late Nineteenth- and Early Twentieth-Century School Curriculum.

    Science.gov (United States)

    Marsden, William E.

    2000-01-01

    Explores the evidence of nationalism, propaganda, and the treatment of war and peace in the school curriculum and textbooks within four countries during the end of the nineteenth century and beginning of the twentieth century: (1) Britain; (2) France; (3) Germany; and (4) the United States. (CMK)

  17. A History of Medicine and the Establishment of Medical Institutions in Middlesex County, New Jersey that Transformed Doctor and Patient Relationships during the Early Twentieth Century

    Science.gov (United States)

    Whitfield-Spinner, Linda

    2011-01-01

    The early twentieth century was a period of tremendous advancements in medicine and technology and as a result experienced a revolutionary change in the delivery of healthcare in America. Modern medicine which encompassed specialized knowledge, technical procedures, and rules of behavior, changed the way medical care was provided in the United…

  18. A History of Medicine and the Establishment of Medical Institutions in Middlesex County, New Jersey that Transformed Doctor and Patient Relationships during the Early Twentieth Century

    Science.gov (United States)

    Whitfield-Spinner, Linda

    2011-01-01

    The early twentieth century was a period of tremendous advancements in medicine and technology and as a result experienced a revolutionary change in the delivery of healthcare in America. Modern medicine which encompassed specialized knowledge, technical procedures, and rules of behavior, changed the way medical care was provided in the United…

  19. Yuben (Monthly Magazine on Oratory) in the Early Twentieth Century: A Case Study in the Promulgation of Western Rhetoric in Japan.

    Science.gov (United States)

    Okabe, Roichi

    The scope, functions, significance, and implications of "Yuben," an early twentieth century Japanese magazine on oratory, are examined in this case study in intercultural rhetoric. The first section of the paper provides information about the magazine's genesis, including a discussion about its originator, Noma Seiji. The second section deals with…

  20. Other than healing: medical practitioners and the business of life assurance during the nineteenth and early twentieth centuries.

    Science.gov (United States)

    Dupree, M W

    1997-04-01

    The purpose of this paper is to explore briefly the nature, development and implications of the relationship between medical practitioners and life assurance companies. The aim is to elucidate the development both of the medical profession and the life insurance business--two important aspects of economic and social change in the nineteenth and early twentieth centuries which are usually treated separately. The focus is primarily, though not exclusively, on Scottish companies as they carried out a disproportionately large amount of the UK life assurance business by the mid-nineteenth century. The insurance industry's increasing, and increasingly systematic, tapping of medical expertise enabled it to raise profits by reducing losses on standard policies and by venturing out into types of business previously thought too risky. While nineteenth-century medical therapeutics may have left much to be desired, medical involvement in insurance suggests that medical practitioners were by no means ineffective. At the same time, a substantial proportion of the medical profession gained valuable part-time appointments which helped to alter the diagnostic techniques of the profession more generally. Thus insurance turns out to be an especially important element in the 'non-healing' aspects of medicine, with spin-offs for the healing side as well.

  1. Allan Brooks, naturalist and artist (1869-1946): the travails of an early twentieth century wildlife illustrator in North America.

    Science.gov (United States)

    Winearls, Joan

    2008-01-01

    British by birth Allan Cyril Brooks (1869-1946) emigrated to Canada in the 1880s, and became one of the most important North American bird illustrators during the first half of the twentieth century. Brooks was one of the leading ornithologists and wildlife collectors of the time; he corresponded extensively with other ornithologists and supplied specimens to many major North American museums. From the 1890s on he hoped to support himself by painting birds and mammals, but this was not possible in Canada at that time and he was forced to turn to American sources for illustration commissions. His work can be compared with that of his contemporary, the leading American bird painter Louis Agassiz Fuertes (1874-1927), and there are striking similarities and differences in their careers. This paper discusses the work of a talented, self-taught wildlife artist working in a North American milieu, his difficulties and successes in a newly developing field, and his quest for Canadian recognition.

  2. From Science to Industry: The Sites of Aluminium in France from the Nineteenth to the Twentieth Century.

    Science.gov (United States)

    Le Roux, Muriel

    2015-05-01

    This paper explores the history of the isolation and industrial production of aluminium in France, from the work of Henri Sainte-Claire Deville in the 1850s to the latter part of the twentieth century, focusing on the relationships between academic research and industrial exploitation. In particular, it identifies a culture and organisation of research and development, "learning-by-doing," that emerged in the French aluminium industry following the establishment of the first electrolytic production facilities in the late 1880s by Paul Héroult, who, along with the American Charles Hall, patented the electrolytic method of producing the metal. This French method of R&D was a product both of a scientific culture that saw a continuity between scientific research and industrial application, and of a state policy that, unlike in Germany or the United States, was late to recognise the importance of fostering, on a large scale, the relations between academic chemistry and industry. It was only after World War II that the French state came fully to recognise the importance of underpinning industry with scientific research. And it was only from the 1960s, in the face of intensifying global competition, the risks of pollution, and the cost of energy, that the major aluminium firm Pechiney et Cie was able to replace a culture of "learning-by-doing" by one that integrated fundamental science with the production process.

  3. The Post-Moden Subject. A Recovery of the Moral Subject after its Abandonmentin the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Carlos Thiebaut Ibarra

    2001-12-01

    Full Text Available How have the conceptions of the subject in Contemporary Philosophy changed? There are four moments in this development: a The ethical conception of enlightened subjectivity; b the different suspicious altitudes of such project in the XIX and XX centuries; e the follow-up of those suspicious altitudes in what is called the philosophies of "malaise" in the XX century; d the new conceptual articulation at the end of the century. Why have these changes and processes occurred? A general interpretive hypothesis belonging to the realm of moral philosophy is suggested: n the realm of practical life we are oriented "forwards" and the subject has aperformative and projective attitude; this dimension becomes opaque when the interpretation of such practica! life is understood as the result or product (and is understood as moving backwards. In light of that hypothesis, the different ways in which the philosophies of suspicion and malaise are blind to the ethical subject are analized and it is claimed that they are. therefore.blind to the ways in which the Twentieth Century has built, against those philosophical interpretations. moral dimensions -as the rejection of damage and the imputation of responsibilities- to which only the last moment of the last century seems to do justice.

  4. WRF Dynamical Downscaling of the Twentieth Century Reanalysis for China 1.Climatic Means during 1981-2010

    Science.gov (United States)

    Kong, Xianghui; Bi, Xunqiang

    2015-04-01

    This study presents a dynamically downscaled climatology over East Asia by using the non-hydrostatic Weather Research and Forecasting (WRF) model, forced by the Twentieth Century Reanalysis (20CR-v2). The whole experiment is a 111 year (1900-2010) continuous run at 50 km horizontal resolution. Climatic means among observations, the driving fields and WRF results during the last three decades (1981-2010) are examined in continental China, and our focus is on surface air (2-m) temperature and precipitation in both summer and winter. WRF dynamically downscaling is able to reproduce the main features of surface air temperature in two seasons in China, and outperforms the driving fields in regional details due to topographic forcing. Surface air temperature biases are reduced as much as 1~2°.For precipitation, the simulated results can reproduce the decreasing pattern from southeast to northwest China in winter. For summer rainfall, the WRF simulated results reproduce the right magnitude of heavy rainfall center around the southeastern coastal area, better than the driving field. One of the significant improvements is that an unrealistic center of summer precipitation in Southeast China in 20CR-v2 is eliminated. However, the simulated results underestimate winter surface air temperature in northern China and winter rainfall in some regions in southeast China.

  5. A brief history of the American radium industry and its ties to the scientific community of its early twentieth century

    Science.gov (United States)

    Landa, E.R.

    1993-01-01

    Federally funded remedial action projects are presently underway in New Jersey and Colorado at sites containing 226Ra and other radionuclides from radium-uranium ore extraction plants that operated during the early twentieth century. They are but the latest chapter in the story of an American industry that emerged and perished in the span of three decades. Major extraction plants were established in or near Denver (CO), Pittsburgh (PA), and New York City (NY) to process radium from ore that came largely from the carnotite deposits of western Colorado and eastern Utah. The staffs of these plants included some of the finest chemists and physicists in the nation, and the highly-refined radium products found a variety of uses in medicine and industry. The discovery of high-grade pitchblende ores in the Belgian Congo and the subsequent opening of an extraction plant near Antwerp, Belgium, in 1992, however, created an economic climate that put an end to the American radium industry. The geologic, chemical, and engineering information gathered during this era formed the basis of the uranium industry of the later part of the century, while the tailings and residues came to be viewed as environmental problems during the same period.

  6. Depravity and Pessimism in the Twentieth Century:Darkness of Human Nature in Lord of the Flies

    Institute of Scientific and Technical Information of China (English)

    赵秋楠

    2015-01-01

    The WWⅡhad a great influence on the people all over the world.People in different ways were expressing their anger.William Golding‘s Lord of the Flies expressed the darkness of human nature after the war.Through the individual symbols, both depravity&pessimism in the twentieth century and darkness of human nature in Lord of the Flies could be well understood.%第二次世界大战给全世界的人们带来了极大的影响,人们也不同的方式来抒发不满。威廉戈尔丁的《蝇王》则抒发了战后人性的黑暗。通过个体象征的运用,20世纪的堕落与悲观主义和《蝇王》中的人性黑暗面得到了很好地理解。

  7. The "Make Love, Not War" Ape: Bonobos and Late Twentieth-Century Explanations for War and Peace.

    Science.gov (United States)

    Weinstein, Deborah

    2016-12-01

    Why do people fight wars? Following the devastation of the Second World War, this question became particularly pressing. Postwar scholars in the human sciences, from political science to anthropology, investigated the role of human nature in the causes of war even as they debated the very meaning of human nature itself. Among the wide-ranging efforts of postwar social and behavioral scientists to explain the causes of war, research on primate aggression became a compelling approach to studying the evolution of human warfare. In contrast, primatologist Frans de Waal's popular and scientific publications on primate reconciliation emphasized the naturalness of conflict resolution and peacemaking, thereby providing a counterpoint to the pessimism of aggression research while simultaneously shoring up the logic of simian analogy. De Waal's popular books heralded the "make love, not war" bonobo as humans' evolutionary next-of-kin and contributed to raising public interest in bonobos during the late twentieth century, although the apes' popular reputation subsequently exceeded the scientific discourse about them. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Slum clearance, privatization and residualization: the practices and politics of council housing in mid-twentieth-century England.

    Science.gov (United States)

    Jones, Ben

    2010-01-01

    This article contributes to a growing literature on working-class suburbanization by arguing that both the residualization and privatization of council housing need to be properly historicized. This case study of housing policy in the borough of Brighton demonstrates that council house sales between the 1950s and 1970s were important in the residualization of inter-war estates well before the 'right to buy' legislation of the 1980s. Concerns about excessively affluent tenants can also be traced to the inter-war period, although it was not until the late 1950s that local Conservatives sought to push affluent council tenants into owner occupation via capping incomes and encouraging council house sales. The article shows that slum clearance had long been central to the local council's provision of municipal housing and that apart from two short periods following the First and Second World Wars, council housing was conceived of primarily as a residual tenure by those in control of policy implementation. It further demonstrates that slum clearance between the 1920s and 1960s altered the social constituency for council housing and, combined with selective privatization, specific allocation policies and disinvestment, led to the stigmatization of certain inter-war estates. The article suggests that further case studies are needed in order to test the wider applicability of these arguments during the middle years of the twentieth century.

  9. Ready, willing, and able to divorce: an economic and cultural history of divorce in twentieth-century Sweden.

    Science.gov (United States)

    Simonsson, Per; Sandström, Glenn

    2011-01-01

    This study outlines a long history of divorce in Sweden, recognizing the importance of considering both economic and cultural factors in the analysis of marital dissolution. Following Ansley Coale, the authors examine how a framework of multiple theoretical constructs, in interaction, can be applied to the development toward mass divorce. Applying a long historical perspective, the authors argue that an analysis of gendered aspects of the interaction between culture and economics is crucial for the understanding of the rise of mass divorce. The empirical analysis finds support for a marked decrease in legal and cultural obstacles to divorce already during the first decades of the twentieth century. However, economic structures remained a severe obstacle that prohibited significant increases in divorce rate prior to World War II. It was only during the 1940s and 1960s, when cultural change was complemented by marked decreases in economic interdependence between spouses, that the divorce rate exhibited significant increases. The authors find that there are advantages to looking at the development of divorce as a history in which multiple empirical factors are examined in conjunction, recognizing that these factors played different roles during different time periods.

  10. On Hans, Zou and the others: wonder animals and the question of animal intelligence in early twentieth-century France.

    Science.gov (United States)

    Lachapelle, Sofie; Healey, Jenna

    2010-03-01

    During the second half of the nineteenth century, the advent of widespread pet ownership was accompanied by claims of heightened animal abilities. Psychical researchers investigated many of these claims, including animal telepathy and ghostly apparitions. By the beginning of the twentieth century, news of horses and dogs with the ability to read and calculate fascinated the French public and scientists alike. Amidst questions about the justification of animal cruelty in laboratory experiments, wonder animals came to represent some extraordinary possibilities associated with their kind. Psychologists speculated on the feats of wonder animals. They considered the possibility that these animals shared consciousness and intelligence with humans, and that-if confirmed-their alleged amazing abilities could lead to a new understanding of cognition for all animals. This article focuses on the few years during which claims of wonder animals occupied a significant place in French psychology and psychical research. It argues that as explanations involving deception or unconscious cues gained increased acceptance, the interest in wonder animals soon led to a backlash in comparative psychology that had repercussions for all animals, particularly those used in experimentation, in that it contributed to the decline of research addressing cognitive abilities in non-human species. Copyright 2009 Elsevier Ltd. All rights reserved.

  11. The Significance Of Space In Iris Murdoch’s The Unicorn As A Twentieth-Century Irish Gothic Novel

    Directory of Open Access Journals (Sweden)

    Jarząb Joanna

    2014-12-01

    Full Text Available During the twentieth century almost all literary genres came back to prominence in different and alternative forms. The Gothic is no exception to this phenomenon as many a writer made an attempt at using this eighteenth-century genre once again, but adding to it some contemporary elements. Consequently, an abundance of new techniques have been introduced to Gothic fiction to evoke the feeling of horror and terror among the more and more demanding readers of modern times. Still, some writers prefer to return to the traditional concept of the Gothic – as does Iris Murdoch in her novel The Unicorn. The purpose of this article is to analyse the text from the perspective of the Irish Gothic. Those features of the genre which are traditional as well as local are going to be discussed in the context of space as the dominating aspect of the novel. The typical Irish landscape abounding in marshes, bogs and the sea will be contrasted with the inner space of the house, and its resemblance to the old Victorian mansions popular among the Anglo-Irish ascendancy of nineteenth-century Ireland. In what follows, the paper aims at showing how Murdoch’s skilful play with the spatial differentiation between the inside and the outside dislodges other more universal issues, such as the question of freedom, of social taboos and of the different anxieties still present in Irish society today.

  12. Mechanism, vitalism and organicism in late nineteenth and twentieth-century biology: the importance of historical context.

    Science.gov (United States)

    Allen, Garland E

    2005-06-01

    The term 'mechanism' has been used in two quite different ways in the history of biology. Operative, or explanatory mechanism refers to the step-by-step description or explanation of how components in a system interact to yield a particular outcome (as in the 'mechanism of enzyme action' or the 'mechanism of synaptic transmission'). Philosophical Mechanism, on the other hand, refers to a broad view of organisms as material entities, functioning in ways similar to machines--that is, carrying out a variety of activities based on known chemical and physical processes. In the early twentieth century philosophical Mechanism became the foundation of a 'new biology' that sought to establish the life sciences on the same solid and rigorous foundation as the physical sciences, including a strong emphasis on experimentation. In the context of the times this campaign was particularly aimed at combating the reintroduction of more holistic, non-mechanical approaches into the life sciences (organicism, vitalism). In so doing, Mechanists failed to see some of the strong points of non-vitalistic holistic thinking. The two approaches are illustrated in the work of Jacques Loeb and Hans Spemann.

  13. Population Genetics with Fluctuating Population Sizes

    CERN Document Server

    Chotibut, Thiparat

    2016-01-01

    Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is reviewed. We then study a situation such that the competing species are neutral at the equilibrium population size but population size fluctuations nevertheless favor fixation of one species over the other. In this case, a separation of timescales emerges naturally and allows adiabatic elimination of a fast population size variable to deduce the fluctuations-induced selection dynamics near the equilibrium population size. The results highlight the incompleteness of the standard population genetics with a strictly fixed population size.

  14. Population Genetics with Fluctuating Population Sizes

    Science.gov (United States)

    Chotibut, Thiparat; Nelson, David R.

    2017-05-01

    Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is reviewed. We then study a situation such that the competing species are neutral at the equilibrium population size but population size fluctuations nevertheless favor fixation of one species over the other. In this case, a separation of timescales emerges naturally and allows adiabatic elimination of a fast population size variable to deduce the fluctuation-induced selection dynamics near the equilibrium population size. The results highlight the incompleteness of the standard population genetics with a strictly fixed population size.

  15. Hypothesis: the reversal of the relation between economic growth and health progress in Sweden in the nineteenth and twentieth centuries was caused by electrification.

    Science.gov (United States)

    Milham, Samuel

    2014-01-01

    The expected decline of health indicators with economic recessions and improvement with economic growth in the nineteenth century Sweden was reversed in the twentieth century, giving the counterintuitive pattern of higher mortality and lower life expectancy in economic expansions and improvement of these indices in recessions. The change or "tipping point" occurred at the end of the nineteenth century or early in the twentieth century when electrification was introduced into Sweden. All 5 of the reversals of annual industrial electric energy use in the US between 1912 and 1970 were accompanied by recessions with lowered GDP, increased unemployment, decreased mortality and increased life expectancy. The health indices were not related to residential electricity use. The mortality improvement between 1931 and 1932 by state in the US strongly favored urban areas over rural areas. Rural unemployment by state in 1930 was significantly positively correlated with residential electrification percentage by state in 1930. The health effects of economic change are mediated by electrical exposure.

  16. Tons of Diplomacy in a borderless sea: discussions about the naval powers of Argentina, Brazil and Chile in the early twentieth century

    Directory of Open Access Journals (Sweden)

    Fernando Ribas De Martini

    2014-07-01

    Full Text Available The evolution of naval powers of Argentina, Brazil and Chile in the early twentieth century was a topic that crossed boundaries not only of countries, but also in sectors from the society of these three nations, involved in discussions about the subject: intellectuals, diplomats, military. Today, this theme crosses boundaries between areas of knowledge such as History of Science, Technique and Technology, Diplomatic History, History of Politics and Social Sciences, as well as studies of Foreign Policy. This article discusses the coincidence concerning the roadmap of the Pan American Conferences of the early twentieth century, which were U.S. initiatives, and the launch and implementation of naval re-equipment plans of these three countries, when much of its intelligentsia discussed these conferences under an anti-american bias.  It also analyzes how this discussion was related more to symbols of naval power than the actual power of these countries.

  17. Social Psychology, Social Science, and Economics: Twentieth Century Progress and Problems, Twenty-First Century Prospects

    Science.gov (United States)

    House, James S.

    2008-01-01

    Stimulated by social scientists' and especially social psychologists' contributions during World War II, as well as by America's post-war economic and population growth, the period from 1945 to 1970 was widely viewed as a "Golden Age" for American social science. Interdisciplinary social psychology arguably was in the vanguard of these…

  18. Diversities Between the Regulations of Turkish Accounting Standard Setters: A Brief History of Turkiye’s Twentieth Century Accounting Standardization Applications

    OpenAIRE

    Yayla, Hilmi Erdogan

    2006-01-01

    This study examines the evolution of Turkish accounting standards to ascertain the extent of differences in Turkiye’s accounting practices among the different governmental Standard setter’s regulations during the twentieth century. The research results show that the accounting standards had set by the public corporates own self as parallel to economic policies of Turkish Ministry of Finance and money policies of Central Bank of the Republic of Turkiye before the establishment of Turkish Accou...

  19. Ambiguous cells: the emergence of the stem cell concept in the nineteenth and twentieth centuries.

    Science.gov (United States)

    Maehle, Andreas-Holger

    2011-12-20

    This paper elucidates the origins of scientific work on stem cells. From the late nineteenth century onwards, the notion of stem cells became customary in scientific communities of Imperial Germany. Adopting the term Stammzelle from Ernst Haeckel, Theodor Boveri was influential in introducing the concept in embryological studies and early genetics around 1900, describing a capacity of stem cells for self-renewal as well as differentiation. At the same time, blood stem cells were conceptualized by histologists such as Ernst Neumann and Artur Pappenheim in studies of physiological haematopoiesis and various forms of leukaemia. Furthermore, building on Julius Cohnheim's theory that tumours arise from 'embryonic remnants' in the adult body, pathologists aimed at identifying the cells of origin, particularly in the embryo-like teratomas. Embryonic stem cells thus assumed an ambiguous status, partly representing common heritage and normal development, and partly being seen as potential causes of cancer if they had been left behind or displaced during ontogeny. In the 1950s and 1960s experimental research on teratocarcinomas by Leroy Stevens and Barry Pierce in the USA brought together the strands of embryological and pathological work. Alongside the work of Ernest McCulloch and James Till at the Ontario Cancer Institute from the early 1960s on stem cells in haematopoiesis, this led into the beginnings of modern stem cell research.

  20. Residential Treatment and the Invention of the Emotionally Disturbed Child in Twentieth-Century America.

    Science.gov (United States)

    Doroshow, Deborah Blythe

    2016-01-01

    In the 1930s, children who were violent, depressed, psychotic, or suicidal would likely have been labeled delinquent and sent to a custodial training school for punitive treatment. But starting in the 1940s, a new group of institutions embarked on a new experiment to salvage and treat severely deviant children. In the process, psychiatrists, psychologists, and social workers at these residential treatment centers (RTCs) made visible, and indeed invented, a new patient population. This article uses medical literature, popular media, and archival sources from several RTCs to argue that staff members created what they called the "emotionally disturbed" child. While historians have described the identification of the mildly "troublesome" child in child guidance clinics, I demonstrate how a much more severely ill child was identified and defined in the process of creating residential treatment and child mental health as a professional enterprise.

  1. Serbian music criticism in the first half of the twentieth century: Its canon, its method and its educational role

    Directory of Open Access Journals (Sweden)

    Vasić Aleksandar

    2008-01-01

    Full Text Available Serbian music criticism became a subject of professional music critics at the beginning of the twentieth century, after being developed by music amateurs throughout the whole previous century. The Serbian Literary Magazine (1901- 1914, 1920-1941, the forum of the Serbian modernist writers in the early 1900s, had a crucial role in shaping the Serbian music criticism and essayistics of the modern era. The Serbian elite musicians wrote for the SLM and therefore it reflects the most important issues of the early twentieth century Serbian music. The SLM undertook the mission of educating its readers. The music culture of the Serbian public was only recently developed. The public needed an introduction into the most important features of the European music, as well as developing its own taste in music. This paper deals with two aspects of the music criticism in the SLM, in view of its educational role: the problem of virtuosity and the method used by music critics in this magazine. The aesthetic canon of the SLM was marked by decisively negative attitude towards the virtuosity. Mainly concerned by educating the Serbian music public in the spirit of the highest music achievements in Europe, the music writers of the SLM criticized both domestic and foreign performers who favoured virtuosity over the 'essence' of music. Therefore, Niccolò Paganini, Franz Liszt, and even Peter Tchaikowsky with his Violin concerto became the subject of the magazine's criticism. However their attitude towards the interpreters with both musicality and virtuoso technique was always positive. That was evident in the writings on Jan Kubelík. This educational mission also had its effect on the structure of critique writings in the SLM. In their wish to inform the Serbian public on the European music (which they did very professionally, the critics gave much more information on biographies, bibliographies and style of the European composers, than they valued the interpretation

  2. A History of Urban Planning and Infectious Diseases: Colonial Senegal in the Early Twentieth Century

    Directory of Open Access Journals (Sweden)

    Liora Bigon

    2012-01-01

    Full Text Available This paper deals with the spatial implications of the French sanitary policies in early colonial urban Senegal. It focuses on the French politics of residential segregation following the outbreak of the bubonic plague in Dakar in 1914, and their precedents in Saint Louis. These policies can be conceived as most dramatic, resulting in a displacement of a considerable portion of the indigenous population, who did not want or could not afford to build à l’européen, to the margins of the colonial city. Aspects of residential segregation are analysed here through the perspective of cultural history and history of colonial planning and architecture, in contrast to the existing literature on this topic. The latter dilates on the statutory policies of the colonial authorities facing the 1914 plague in Dakar, the plague's sociopolitical implications, and the colonial politics of public health there. In the light of relevant historiography, and a variety of secondary and primary sources, this paper exposes the contradictions that were inherent in the French colonial regime in West Africa. These contradictions were wisely used by the African agency, so that such a seemingly urgent segregationist project was actually never accomplished.

  3. P A Jungian Approach to Self-fragmentation of Twentieth Century in Orwell’s Nineteen Eighty Four

    Directory of Open Access Journals (Sweden)

    Mozhdeh Alizadeh Shirazi

    2014-11-01

    Full Text Available The problematic life of modern human has always been a significant issue for many areas of study. In reaction to the absence of romantic values and the unity of the pre-modern world, Human being was afflicted with a sense of inner crises which is referred to as self-fragmentation. Fragmentation is one of the significant features of twentieth century when a mode of anxiety subjugated both art and society. In such an atmosphere many writers of the modern century attempted to reflect in their works of literature, what they had experienced in the real world. Orwell’s Nineteen Eighty Four is one of the popular novels of Modern Era that describes a modern but fragmented society wherein the modern human’s lack of self-integration is perceptible. By representing how the protagonists respond to the voices of their psyches through characterization and dreams, which is also of crucial significance in Jung’s Analytical Psychology, Orwell explores the roots of modern human’s urge for achieving a cohesive sense of self. Accordingly, this study, attempts to illustrate how modern human steps in the path of individuation and to what extent these efforts meet with success, if any. To achieve this goal, some terms and notions of Jungian Criticism such as archetypes and the process of individuation will be borrowed, and a particular focus will be held on dreams occurring in the course of the story. In addition, this paper would like to argue that the dystopian society portrayed in these novels is the offspring of a mere rationalism which prevents human from knowing the opposing forces working within as well as the forces functioning from without.

  4. Revolutions in twentieth-century physics; Einfuehrung in die Physik des 20. Jahrhunderts. Relativitaetstheorie, Quantenmechanik, Elementarteilchenphysik und Kosmologie

    Energy Technology Data Exchange (ETDEWEB)

    Griffiths, David J. [Reed College, Portland, OR (United States). Howard-Vollum-Professur fuer Naturwissenschaften

    2015-07-01

    Relativity theory, quantum mechanics, elementary-particle physics, and cosmology are the four pillars of modern physics. The life in the 21th century is without them no more conceivable: The special relativity theory renewed our understanding of space and time, on the laws of quantum mechanics are based countless everyday objects like transistors, computer chips, and mobile telephones; in particle accelerators we study the components oof matter, and with telescopes we take an ever deeper look in the past of the universe. Taking reference books to these themes at hand, one is overwhelmed by the plethora and complexity of the mathematical formulas. This book of the renowned professor of physics David J. Griffiths id refreshingly different. By means of many illustrative examples and entertaining stories it introducts to the themes and helps the reader also without a large mathematical apparatus to a fundamental understanding of that, about which Einstein, Schroedinger, Heisenberg, and Hubble actually thought and spoke. In each chapter numerous, pedagogically selected examples are completely worked out, in order to fill the matter with life. Moreover the text contains a manifold of problems, which allow the reader to deepen his knowledge and apply immediately. Griffith's ''Revolution in Twentieth Century Physics'' appeals not only to pupils and future studyings of natural sciences, who want to get an appetite for what lies ahead, but also to interested readers, which have already heared in the media from quarks and quanta, the curved space-time, Albert Einstein, and the big bang and now want to understandably know what is at stake in all the excitement.

  5. Summer rainfall variability in European Mediterranean mountains from the sixteenth to the twentieth century reconstructed from tree rings.

    Science.gov (United States)

    Ruiz-Labourdette, D; Génova, M; Schmitz, M F; Urrutia, R; Pineda, F D

    2014-09-01

    Since the end of the last glacial period, European Mediterranean mountains have provided shelter for numerous species of Eurosiberian and Boreal origin. Many of these species, surviving at the southern limit of their range in Europe and surrounded by Mediterranean ones, are relatively intolerant to summer drought and are in grave danger of loss, as a result of increasingly long and frequent droughts in this region. This is the case of the Scots pine (Pinus sylvestris) and the Austrian pine (Pinus nigra ssp. salzmannii) which are found on Central Iberian Peninsula at the edge of their natural range. We used a tree ring network of these two species to reconstruct past variations in summer rainfall. The reconstruction, based upon a tree ring composite chronology of the species, dates back to 1570 (adjusted R(2) = 0.49, P tree radial growth, we employed a principal component analysis to calculate the resultant of the relationship between the growth data of both species, using this resultant as a dependent variable of a multiple regression whose independent variables are monthly mean temperature and precipitation from the average records. Spatial correlation patterns between instrumental precipitation datasets for southern Europe and reconstructed values for the 1950-1992 period indicate that the reconstruction captures the regional signal of drought variability in the study region (the origin of this precipitation is convective: thermal low pressure zones induced in the inland northeastern areas of the Iberian Peninsula). There is a clear increase in the recurrence of extreme dry events as from the beginning of twentieth century and an abrupt change to drier conditions. There appears to be a tendency toward recurrent exceptionally dry summers, which could involve a significant change for the Eurosiberian refugee species.

  6. Women as food producers and suppliers in the twentieth century. The case of Zambia.

    Science.gov (United States)

    Muntemba, S

    1982-01-01

    It is argued in this discussion that women's ability to produce and supply food has been deteriorating over time. Although this may have begun in precolonial times, particularly with the advent of merchant capital, 20th century economic and political developments have accelerated the process. This situation applies to peasant production as a whole, but discussion is limited to food production and supply. The discussion attempts to understand and discuss the position of women as food producers and suppliers within the framework of the social relations of production, distribution, and surplus appropriation. Land and labor issues have affected women's food production capabilities adversely, and their ability to supply food has been deteriorating. In those countries where their husbands are wage laborers, women have both fed themselves and their children and have supplemented their husbands' wages through food gifts and by maintaining them during their stay at home before the cycle begins again. Despite the fact that they could not adequately do so, men were obligated to start partially maintaining their families "back home" through cash remittances, but cash came at irregular intervals, or it was insufficient, mainly because of small wages. Some women have tried to increase their food supply capacities by going into seasonal wage labor, but often the wages are too low and the prices of food too high for this strategy to work. The time spent in wage labor could be better spent in their own production, provided the factors of production are favorable to them. The intensification of cash crop production has drawn land and labor away from food crops resulting in local food shortages. This process was realized earlier in West Africa when the colonial government started to import rice from China. Gradually, this became an acceptable food crop, but attempts to grow it in sufficient quantities have benefited only men. With the growing urban population rice became a viable

  7. Twentieth century demographic changes in cirio and cardón in Baja California, Mexico

    Science.gov (United States)

    Bullock, Stephen H.; Martijena, Nora E.; Webb, Robert H.; Turner, Raymond M.

    2005-01-01

    exposures for both species. The residual variations were not clearly affected, at a regional scale, by other factors thought to be important, including elevation, distance to the Pacific Ocean, geology, slope gradient, soil stability, older vs. young alluvial soils, and soil Ca : Mg and Na : K ratios. Human impacts have been sporadic and heterogeneous but locally strong; our quantitative indices of accessibility did not show regionally significant effects. Blowdown by hurricanes is a sporadic cause of major mortality for cirio but not necessarily for cardón. Main conclusions  At our scales, effects of time outweigh those of substrate, and human impact was scant. Large patterns were pronounced: cirio experienced a prolonged, widespread decline in the 1900s, while cardón fluctuated in different directions and degree among local populations. Cirio was found to be inherently much shorter-lived than cardón. We also suggest that recruitment in cirio was low due to long periods with relatively dry winters that affected the entire region, while spatial heterogeneity of cardón recruitment seemed more related to the variation in summer rains.

  8. Population Genetics with Fluctuating Population Sizes

    OpenAIRE

    Chotibut, Thiparat; Nelson, David R.

    2016-01-01

    Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is reviewed. We then study a situation such that the competing species are neutral at the equilibrium population size but population size fluctuations nevertheless favor fixation of one species over the other. In this case, a separation of timescales emerges natural...

  9. in the twentieth century

    African Journals Online (AJOL)

    Baker. They were naturally concerned to represent their hero as favourably as ... front of the Rhodes Building is a statue of Rhodes; beneath his feet are statues ... On the same day a memorial service was held at St Paul's Cathedral in London ...

  10. Coupled Aerosol-Chemistry-Climate Twentieth-Century Transient Model Investigation: Trends in Short-Lived Species and Climate Responses

    Science.gov (United States)

    Koch, Dorothy; Bauer, Susanne E.; Del Genio, Anthony; Faluvegi, Greg; McConnell, Joseph R.; Menon, Surabi; Miller, Ronald L.; Rind, David; Ruedy, Reto; Schmidt, Gavin A.; Shindell, Drew

    2011-01-01

    The authors simulate transient twentieth-century climate in the Goddard Institute for Space Studies (GISS) GCM, with aerosol and ozone chemistry fully coupled to one another and to climate including a full dynamic ocean. Aerosols include sulfate, black carbon (BC), organic carbon, nitrate, sea salt, and dust. Direct and BC snow-albedo radiative effects are included. Model BC and sulfur trends agree fairly well with records from Greenland and European ice cores and with sulfur deposition in North America; however, the model underestimates the sulfur decline at the end of the century in Greenland. Global BC effects peak early in the century (1940s); afterward the BC effects decrease at high latitudes of the Northern Hemisphere but continue to increase at lower latitudes. The largest increase in aerosol optical depth occurs in the middle of the century (1940s-80s) when sulfate forcing peaks and causes global dimming. After this, aerosols decrease in eastern North America and northern Eurasia leading to regional positive forcing changes and brightening. These surface forcing changes have the correct trend but are too weak. Over the century, the net aerosol direct effect is -0.41 Watts per square meter, the BC-albedo effect is -0.02 Watts per square meter, and the net ozone forcing is +0.24 Watts per square meter. The model polar stratospheric ozone depletion develops, beginning in the 1970s. Concurrently, the sea salt load and negative radiative flux increase over the oceans around Antarctica. Net warming over the century is modeled fairly well; however, the model fails to capture the dynamics of the observedmidcentury cooling followed by the late century warming.Over the century, 20% of Arctic warming and snow ice cover loss is attributed to the BC albedo effect. However, the decrease in this effect at the end of the century contributes to Arctic cooling. To test the climate responses to sulfate and BC pollution, two experiments were branched from 1970 that removed

  11. Between biomedical and psychological experiments: The unexpected connections between the Pasteur Institutes and the study of animal mind in the second quarter of twentieth-century France.

    Science.gov (United States)

    Thomas, Marion

    2016-02-01

    This article explores the unexpected connections between the Pasteur Institute in French Guinea and the study of animal mind in early twentieth century France. At a time when the study of animal intelligence was thriving in France and elsewhere, apes were appealing research subjects both in psychological and biomedical studies. Drawing on two case studies (Guillaume/Meyerson and Urbain), and then, on someone responding negatively to those connections, Thétard, this article shows how the long reach of biomedicine (linked to the prestige of Bernard and Pasteur) impinged on French biology and played a role in the tortuous, if not unsuccessful fate of animal psychology in France in the second quarter of the twentieth century. It shows how attempts to use apes (and other zoo animals) to yield new insights on animal psychology faced heavy restrictions or experienced false starts, and examines the reasons why animal psychology could not properly thrive at that time in France. Beyond the supremacy of biomedical interests over psychological ones, this article additionally explains that some individuals used animal behaviour studies as steppingstones in careers in which they proceeded on to other topics. Finally, it illustrates the tension between non-academic and academic people at a time when animal psychology was trying to acquire scientific legitimacy, and also highlights the difficulties attached to the scientific study of animals in a multipurpose and hybrid environment such as the early twentieth century Parisian zoo and also the Pasteur Institute of French Guinea. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. The treatment of madness in the nineteenth and twentieth centuries: discourses about curability in Spanish mental health care, 1890-1917.

    Science.gov (United States)

    Domingo, José Javier Plumed; Moreno, Luis Miguel Rojo

    2016-01-01

    This article studies the discourses about curability constructed by Spanish mental health practitioners in the transition from the nineteenth to the twentieth century. While in the 1870s and 1880s the predominant discourse promoted by doctors attached to private institutions was extremely optimistic, it subsequently changed and became more pessimistic regarding treatment outcomes. However, given phrenopathists' professional needs, they continued to profess more or less unshakeable confidence in the therapeutic abilities of psychiatry. The reception of new nosologies, such as Kraepelin's, depended in part on contemporary mental health practitioners' stance on curability and was accompanied by ambivalence.

  13. A grotesque carnival on the sea: twentieth-century revisitings of the “Ship of fools” (from Conrad to Fellini)

    OpenAIRE

    Paolo Lago

    2016-01-01

    This essay offers, through a comparative reading, an analysis of the survival of the grotesques and carnival elements, studied by Michail Bachtin, in the representation of new “ships of fools” in some novels and films in the twentieth-century. Some ships in Joseph Conrad’s and Louis-Ferdinand Céline’s novels (Typhoon, 1902, The Shadow-Line, 1917, Voyage au bout de la nuit, 1932) are full of sick bodies depicted as grotesques carnival masks, the same bodies that we can find on the “death ship”...

  14. A grotesque carnival on the sea: twentieth-century revisitings of the “Ship of fools” (from Conrad to Fellini

    Directory of Open Access Journals (Sweden)

    Paolo Lago

    2016-11-01

    Full Text Available This essay offers, through a comparative reading, an analysis of the survival of the grotesques and carnival elements, studied by Michail Bachtin, in the representation of new “ships of fools” in some novels and films in the twentieth-century. Some ships in Joseph Conrad’s and Louis-Ferdinand Céline’s novels (Typhoon, 1902, The Shadow-Line, 1917, Voyage au bout de la nuit, 1932 are full of sick bodies depicted as grotesques carnival masks, the same bodies that we can find on the “death ship”, destined to shipwreck, in the homonymous novel by B. Traven (The Death Ship, 1926. In the tale Un viaje terrible (1941 by Roberto Arlt and in the novel Ship of Fools (1962 by Katherine Anne Porter, the ship of fools is a metaphoric microcosm where is reflected the whole humanity. On the other hand, Federico Fellini reproposes the grotesques and carnival characteristics in the representation of body, especially regard to characters embarked on Lica’s ship in the Fellini-Satyricon (1969 or on the ship in E la nave va (1983. The survival of the ship of fools, in the twentieth-century, therefore, is characterized by a constant reference to ‘grotesque’ and carnival studied by Bachtin.

  15. Climate and climate change in the Austrian-Swiss region of the European Alps during the twentieth century according to Feddema

    Science.gov (United States)

    Ács, Ferenc; Takács, Dominika; Breuer, Hajnalka; Skarbit, Nóra

    2017-07-01

    Feddema's generic climate classification method is applied to study climate and climate change in the Austrian-Swiss region of the European Alps during the course of the twentieth century. A fine-tuned version of it is also tested in addition to the original scheme. Monthly precipitation and air temperature data at a spatial resolution of 10' × 10' are taken from the Climatic Research Unit TS 1.2 database to construct 30- and 50-year period averages. It is shown that the alpine climate is sufficiently heterogeneous to make it unnecessary to perform fine-tuning of the original scheme for its characterization on the meso-β scale (20-200 km). It is also demonstrated that data organizational effects are much less intense than the effects caused by the fine-tuning. The area heterogeneity of climate and climate change types is the highest in the vicinity of lakes (Austria: Lake Constance; Switzerland: Lakes Geneva, Neuchâtel, Biel, Zurich, and Constance) and along river valleys (Austria: the Danube, Drava, and Mur; Switzerland: the Aare and Ticino). The dominant climate change process was drying in Austria and warming in Switzerland. Large areas characterized by cold and saturated climate in the Central Eastern Alps did not experience climate change during the twentieth century.

  16. 二十世纪音乐语言与视唱教学%Music Language and Sight-singing Teaching in the Twentieth Century

    Institute of Scientific and Technical Information of China (English)

    张晓燕

    2011-01-01

    二十世纪音乐进入了多元风格的时代,这一时期的音乐创作既有与传统保持明显的继承关系的有调中心音乐,也有探索性极强的各种无调中心音乐,包括创立序列音乐的新维也纳乐派、非控制音乐等。通过对二十世纪音乐语言的梳理,总结了一些可进行操作的教学方法,以便让学生更好地学习和研读其作品。%The twentieth century music entered the times of multicultural styles.The music creation in this period has not only central music with key which keeps obvious inheriting relationship with tradition,but also strong explorative central music without key,including the creation of new Vienna School of serial music,non-controlled music and so on.Through analyzing the music language in the twentieth century,this paper summarizes some teaching methods for conducting operation so that students can study and research their works better.

  17. Population genetic structure and ecotoxicology.

    OpenAIRE

    Guttman, S I

    1994-01-01

    Electrophoretic analyses of population genetic structure, both in the laboratory and in the field, have documented significant shifts in allozyme genotype frequencies in a variety of aquatic taxa as a result of environmental impacts. Studies are documented which indicate that contaminants may select for individuals with tolerant allozyme genotypes, causing the potential loss of individuals with sensitive genotypes. This may diminish the genetic variability and fitness of affected populations ...

  18. The historical significance of the Trepça mine in the Region of Stan-Terg during the twentieth century

    Directory of Open Access Journals (Sweden)

    Mustafë Haziri

    2015-11-01

    Full Text Available The historical significance of the Trepça’s mine in Stan-Terg is so big, that it is impossible to be presented in this scientific paper, because of its historic, economic and social character. This paper analyses chronologically the importance of Trepça mine, focusing with particular emphasis on the period of the twentieth century where in 1926 the first research that was implemented by the British government began. In 1930 began the modern exploitation of Trepça which was followed by some union movements which lasted until 1939. In 1941, Trepça fell into the hands of the nazi regime of Germany. Other aspects of this work include the period of the Second World War, when the nationalization of property was implemented during the communist regime in former Yugoslavia until the great strike of 1989.

  19. Love Practices in the Colombian School during the First Half of the Twentieth Century: Notes for a History of Feminine Love

    Directory of Open Access Journals (Sweden)

    Claudia Ximena Herrera Beltrán

    2016-08-01

    Full Text Available In Latin America women increasingly detach themselves from feminine representations produced by certain discourses of modernity. However, unequal relations, binary constructions of sex and gender, and exclusion whenever there is any sign of resistance are still signs of contemporaneity. In response to this situation, this research paper shows, through an archaeological and genealogical study, how love, as a feeling and emotion, was a subject of education for girls in the Colombian school during the first half of the twentieth century. In that sense, the author reflects upon emotions, feelings and discourses, and reveals how society shaped practices and legitimized truths that, even today, define both men’s and women’s nature.

  20. The sea as science: ocean research institutions and strategies in Portugal in the twentieth century (from the First Republic to democracy).

    Science.gov (United States)

    Rollo, Maria Fernanda; Queiroz, Maria Inês; Brandão, Tiago

    2014-01-01

    Historical perspective has revealed the many aspects of Portugal's interest in the sea, evident in a series of initiatives and entities throughout the twentieth century. From the beginning of the century until the 1974 Revolution, the genesis of organizations devoted to the scientific study of the sea is analyzed, observing their specific missions in the context of the formulation of science policy, and more specifically "ocean policies." The Portuguese valued knowledge of the sea due to their maritime vocation, coastal life and geographic position. Traversing different historical and political contexts and development cycles, the assumptions and political implications that accentuate the strategic dimension of science policy, visible in the geopolitical affirmation of oceanography, are studied.

  1. Fairy tales, children’s books and schools in Sweden and Italy in the late nineteenth and early twentieth centuries. Historical comparisons and pedagogical remarks

    Directory of Open Access Journals (Sweden)

    William Grandi

    2014-06-01

    Full Text Available This paper examines some historical parallels in the field of children’s literature and education between Sweden and Italy in the late nineteenth and early twentieth centuries. Sweden and Italy are at the opposite ends of Europe, but they exhibited some interesting similarities in children’s book and pedagogy during those decades. Suffice it to say that two of the most important European education experts of the time – the Swede Ellen Key and the Italian Maria Montessori – were in relationship, appreciated each other’s work and exchanged ideas and remarks on educational and social issues. Parallels cannot obscure the large differences between the two nations, but there were also convergences that must be examined: researches on folktales, mass education and education of the élite were important issues in both countries. Moreover the convergences will intensify further in the coming decades, because Sweden and Italy belong to the same European context.

  2. 'They accused me of strangling her:' epilepsy and violence debate in Croatia at the end of the nineteenth and the beginning of the twentieth centuries.

    Science.gov (United States)

    Kuhar, Martin; Fatović-Ferenčić, Stella

    2017-07-01

    Nineteenth-century psychiatry shifted its focus to the brain as the seat of mental disorders. With a new understanding of mental disorders arose the need to consult forensic psychiatrists in cases of criminal acts committed by persons with mental illness. This article focuses on three murders committed by 'epileptics' at the end of the nineteenth and the beginning of the twentieth centuries in Croatia. An analysis of these cases will help to situate forensic psychiatry at the turn of the century within the Austro-Hungarian Empire, and reveal the authority that forensic experts wielded in the courts. We will argue that Cesare Lombroso's biological theory of crime, as well as the influence of eugenicists and pharmaceutical companies, shaped the long-standing relationship between epilepsy and violent behaviour.

  3. [São Paulo residents known as "Southern Yankees" and the "modern disease," namely neurasthenia, in the early decades of the twentieth century].

    Science.gov (United States)

    Dorsch, Sebastian

    2014-01-01

    In a brief period of time the coffee boom, European immigration and the "atlanticization" of various sectors of life saw São Paulo transform from a small village into a thriving Atlantic metropolis. In the early decades of the twentieth century, observers described the city as Yankee City, due to its progress and activity. To what extent does neurasthenia, namely "the most modern and American of disorders", tally with that image? After analysis of advertisements, scientific books and texts for the dissemination of science, as well as articles in journals, it can be stated that neurasthenia was prevalent and widespread. This work emphasizes the socio-cultural familiarity of São Paulo with the phenomenon of neurasthenia.

  4. The Innovative Work of S. S. Glagolev: Theism in Russian Theological Academies of the Beginning of the Twentieth Century and Its Focusing on the Problem of Man

    Directory of Open Access Journals (Sweden)

    Marjana Ershova

    2015-02-01

    Full Text Available The author details the results of her study of the works of Sergey Sergeyevich Glagolev, a prominent professor of the Moscow Theological Academy. Glagolev’s heritage produces a profound impression by means of its versatility, its original way of looking at diverse problems as well as his unique solutions to the same problems. For this reason, it possesses enduring relevance. Despite this fact, his correspondence is still not well known nor understood. The author focuses on Glagolev’s analysis of the human problem. This choice may be explained by the fact that Sergey Sergeevich considered the problem of man to be the key issue behind the collision of religion and science taking place during the early twentieth century. Glagolev attempted to solve this problem by focusing on certain aspects of the subject: the origin of mankind, the interaction of the spirit and the body, the immortality of the soul, the origin of religion, as well as the way in which religious faith came about. A vital aspect of Glagolev’s treatment of the problem of man is his criticism of Charles Darwin and Darwinism, and thereby of the entire theory of evolution. Glagolev disagreed with the basic premises of this theory as well as with some of its specific conclusions. While opposing the concept of anthropo-genesis, Glagolev formulated his own theory regarding the origins of mankind. Thus, Glagolev viewed the origins and later history of mankind through the prism of his theory of degradation, which allowed him to seamlessly link the biblical narrative of the origins of man with contemporary scientific data. The author concludes that Glagolev was a major influence in the development of Russian theology during the first years of the twentieth century.

  5. Energy budgets and transports: global evolution and spatial patterns during the twentieth century as estimated in two AMIP-like experiments

    Science.gov (United States)

    Lembo, Valerio; Folini, Doris; Wild, Martin; Lionello, Piero

    2017-03-01

    This study describes characteristics and evolution of the residual of the Earth energy budget (EB) individual components and the implied meridional transports during the twentieth century. This analysis considers two ensembles of AMIP-like experiments (Atmospheric Model Intercomparison Project) with prescribed evolution of sea surface temperature and sea ice concentration (SST-SIC), greenhouse gases (GHG), anthropogenic and volcanic aerosols over the entire twentieth century: ERA-20CM and ECHAM5-HAM model simulations. With the latter, additional sensitivity experiments are carried out by constraining either SST-SIC or aerosols to climatological values. The two models provide compatible estimates of the EBs and implied transport absolute values in recent decades. They are not in agreement in terms of global scale evolution: in the 1970s ERA-20CM shows a fast transition from negative to positive EBs at top of atmosphere (TOA) that is not found in ECHAM5-HAM. Climatological SST-SIC sensitivity experiments evidence that the aerosol forcing affects TOA and surface EBs by setting up an inter-hemispheric gradient after 1960. This is also reflected by an increased total transport in the Northern Hemisphere, while decreased in the Southern Hemisphere. ERA-20CM shows no evidence of a similar aerosol forcing. Sensitivity experiments with fixed pre-industrial aerosols show that transient SST are responsible for irregular spatio-temporal anomalies of surface and atmospheric EBs and transports. Surface and atmospheric anomalies oppose each other, and transient SSTs do not influence the EB changes at TOA. Impact of transient SST and GHG forcing on EBs and implied transports are robust across the two models.

  6. Urban music from Kosovo and Metohija in the researches of Serbian ethnomusicologists up to the second half of the twentieth century

    Directory of Open Access Journals (Sweden)

    Dumnić Marija

    2013-01-01

    Full Text Available Folk music of Serbs from Kosovo and Metohija is considered to be archaic in popular discourse. From the scientific side, that is supported by the ethnomusicological printed and sound recordings, which are one of the first sources about Serbian music folklore. Ethnomusicology in Serbia is based on the results of music ethnography of the nineteenth and the twentieth century, and because of that, it is primary focused on rural tradition. Also in the last years’, popular music arrangements of some of these songs are often, whereby music from Kosovo and Metohija is usually perceived as the rural heritage. Nevertheless, music recorded during pioneer ethnomusicological fieldworks in Kosovo and Metohija is mostly noted in the cities, in organized “unauthentic” situations, and the performers were craftsmen, traders and teachers. Although in the latter ethnomuscological literature music classification according to the ritual background was common, the most of the songs recorded on Kosovo and Metohija have not (strict ritual function and subject matter. The analysis of the Kosovo and Metohija songbooks of the eminent ethnomusicologists from Serbia proved that urban folk music was very present in the field, but troublesome for regular ethnomusicological classification and interpretation, and also that there were several informants with urban settlement who performed for these ethnomusicologists plenty of folk songs. Since the first half of the twentieth century, these ethnomusicological results have had great result on the popularization of Kosovo and Metohija music heritage. The main goal of this paper is to point on unjustified marginalization of the urban folklore at the ethnomusicological discourse, to illuminate the approaches of the pioneers in ethnomusicology in Serbia to the music heritage which has special significance not only in expert framework and to discuss the role of ethnomusicologist in the creation of the notion of “folk song

  7. Energy budgets and transports: global evolution and spatial patterns during the twentieth century as estimated in two AMIP-like experiments

    Science.gov (United States)

    Lembo, Valerio; Folini, Doris; Wild, Martin; Lionello, Piero

    2016-05-01

    This study describes characteristics and evolution of the residual of the Earth energy budget (EB) individual components and the implied meridional transports during the twentieth century. This analysis considers two ensembles of AMIP-like experiments (Atmospheric Model Intercomparison Project) with prescribed evolution of sea surface temperature and sea ice concentration (SST-SIC), greenhouse gases (GHG), anthropogenic and volcanic aerosols over the entire twentieth century: ERA-20CM and ECHAM5-HAM model simulations. With the latter, additional sensitivity experiments are carried out by constraining either SST-SIC or aerosols to climatological values. The two models provide compatible estimates of the EBs and implied transport absolute values in recent decades. They are not in agreement in terms of global scale evolution: in the 1970s ERA-20CM shows a fast transition from negative to positive EBs at top of atmosphere (TOA) that is not found in ECHAM5-HAM. Climatological SST-SIC sensitivity experiments evidence that the aerosol forcing affects TOA and surface EBs by setting up an inter-hemispheric gradient after 1960. This is also reflected by an increased total transport in the Northern Hemisphere, while decreased in the Southern Hemisphere. ERA-20CM shows no evidence of a similar aerosol forcing. Sensitivity experiments with fixed pre-industrial aerosols show that transient SST are responsible for irregular spatio-temporal anomalies of surface and atmospheric EBs and transports. Surface and atmospheric anomalies oppose each other, and transient SSTs do not influence the EB changes at TOA. Impact of transient SST and GHG forcing on EBs and implied transports are robust across the two models.

  8. Population genetics without intraspecific data

    DEFF Research Database (Denmark)

    Thorne, Jeffrey L; Choi, Sang Chul; Yu, Jiaye

    2007-01-01

    A central goal of computational biology is the prediction of phenotype from DNA and protein sequence data. Recent models of sequence change use in silico prediction systems to incorporate the effects of phenotype on evolutionary rates. These models have been designed for analyzing sequence data...... populations, and parameters of interspecific models should have population genetic interpretations. We show, with two examples, how population genetic interpretations can be assigned to evolutionary models. The first example considers the impact of RNA secondary structure on sequence change, and the second...... reflects the tendency for protein tertiary structure to influence nonsynonymous substitution rates. We argue that statistical fit to data should not be the sole criterion for assessing models of sequence change. A good interspecific model should also yield a clear and biologically plausible population...

  9. Wolf population genetics in Europe

    DEFF Research Database (Denmark)

    Hindrikson, Maris; Remm, Jaanus; Pilot, Malgorzata

    2017-01-01

    The grey wolf (Canis lupus) is an iconic large carnivore that has increasingly been recognized as an apex predator with intrinsic value and a keystone species. However, wolves have also long represented a primary source of human–carnivore conflict, which has led to long-term persecution of wolves......, resulting in a significant decrease in their numbers, genetic diversity and gene flow between populations. For more effective protection and management of wolf populations in Europe, robust scientific evidence is crucial. This review serves as an analytical summary of the main findings from wolf population...... (Y chromosome) and biparental [autosomal microsatellites and single nucleotide polymorphisms (SNPs)]. To describe large-scale trends and patterns of genetic variation in European wolf populations, we conducted a meta-analysis based on the results of previous microsatellite studies and also included...

  10. What is Behind Yinshun’s Re-statement of the Nature of the Mūlamadhyamakakā : Debates on the Creation of a New Mahāyāna in Twentieth-century China

    NARCIS (Netherlands)

    Travagnin, Stefania

    2012-01-01

    Yinshun (1906–2005) is regarded as one of the most eminent monks in twentieth-century Chinese Buddhism. Previous research has argued that Yinshun especially undertook the mission of writing new commentaries on Madhyamaka texts. His efforts provoked a revival of interest towards the Madhyamaka school

  11. Formalism in the first half of the twentieth century: ‘pure science’ or a case of effective rhetoric? [Review of: M.B. Frank, D. Adler German art history and scientific thought: beyond formalism

    NARCIS (Netherlands)

    Witte, A.

    2012-01-01

    German Art History and Scientific Thought - Beyond Formalism discusses the relation between art history and the human and natural sciences in the late nineteenth and early twentieth centuries. All contributions in this volume highlight the way in which this exchange affected art history on a practic

  12. Microsatellite data analysis for population genetics.

    Science.gov (United States)

    Kim, Kyung Seok; Sappington, Thomas W

    2013-01-01

    Theories and analytical tools of population genetics have been widely applied for addressing various questions in the fields of ecological genetics, conservation biology, and any context where the role of dispersal or gene flow is important. Underlying much of population genetics is the analysis of variation at selectively neutral marker loci, and microsatellites continue to be a popular choice of marker. In recent decades, software programs to estimate population genetics parameters have been developed at an increasing pace as computational science and theoretical knowledge advance. Numerous population genetics software programs are presently available to analyze microsatellite genotype data, but only a handful are commonly employed for calculating parameters such as genetic variation, genetic structure, patterns of spatial and temporal gene flow, population demography, individual population assignment, and genetic relationships within and between populations. In this chapter, we introduce statistical analyses and relevant population genetic software programs that are commonly employed in the field of population genetics and molecular ecology.

  13. Genetic structure of chimpanzee populations.

    Directory of Open Access Journals (Sweden)

    Celine Becquet

    2007-04-01

    Full Text Available Little is known about the history and population structure of our closest living relatives, the chimpanzees, in part because of an extremely poor fossil record. To address this, we report the largest genetic study of the chimpanzees to date, examining 310 microsatellites in 84 common chimpanzees and bonobos. We infer three common chimpanzee populations, which correspond to the previously defined labels of "western," "central," and "eastern," and find little evidence of gene flow between them. There is tentative evidence for structure within western chimpanzees, but we do not detect distinct additional populations. The data also provide historical insights, demonstrating that the western chimpanzee population diverged first, and that the eastern and central populations are more closely related in time.

  14. Stochastic problems in population genetics

    CERN Document Server

    Maruyama, Takeo

    1977-01-01

    These are" notes based on courses in Theoretical Population Genetics given at the University of Texas at Houston during the winter quarter, 1974, and at the University of Wisconsin during the fall semester, 1976. These notes explore problems of population genetics and evolution involving stochastic processes. Biological models and various mathematical techniques are discussed. Special emphasis is given to the diffusion method and an attempt is made to emphasize the underlying unity of various problems based on the Kolmogorov backward equation. A particular effort was made to make the subject accessible to biology students who are not familiar with stochastic processes. The references are not exhaustive but were chosen to provide a starting point for the reader interested in pursuing the subject further. Acknowledgement I would like to use this opportunity to express my thanks to Drs. J. F. Crow, M. Nei and W. J. Schull for their hospitality during my stays at their universities. I am indebted to Dr. M. Kimura...

  15. A contextual analysis of nervous force in medico-scientific and literary writings in English of the nineteenth and early-twentieth centuries.

    Science.gov (United States)

    Lazar, J Wayne

    2015-01-01

    This study concerns the context of use of the term "nervous force," as it appears in scientific and literary publications in English over the course of the nineteenth century and the first two decades of the twentieth century. The context of use, loss, or waste of nervous force and the context of nervous force as an expression of an attribute are analyzed in 189 scientific and 105 literary writings. Both contexts appeared in literary writings, where nervous force expresses the attributes of strength, forcefulness, vigor, or energy and use, loss or waste of nervous force explains such nonmorbid conditions as why someone is tired or needs rest. Only the context of use-loss-waste appeared in the medico-scientific literature, but here it explained both nonmorbid conditions (for example, effects of old age) and morbid conditions (like epilepsy). Changes in the number of these references give insights into the medico-scientific and the literary disciplines. Discussions include why nervous force is associated with explanation of disease, the persistence of its use in this capacity, and its influence on a similar use in literary writings.

  16. PAZ, PRI, AND PROGRESS: OCTAVIO PAZ’S POLITICAL, ECONOMIC AND LITERARY STRUGGLE TO INSPIRE REFORM IN TWENTIETH-CENTURY MEXICO

    Directory of Open Access Journals (Sweden)

    D. Gene Pace

    2003-01-01

    Full Text Available Throughout most of the twentieth century; Mexico’s political and economic policies were heavily influenced by the Partido Revolucionario Institutional (PRI. The landmark 1998 victory by Vicente Fox, the first presidential candidate in seven decades to win without the official sanction of the PRI,marked an important milestone in Mexican history; Octavio Paz, an eloquent proponent of political, economic, and social reform, sought for decades to inspire change. This paper seeks to illuminate Paz’s economic philosophy, and to demonstrate how the acclaimed writer, through courageous symbolic action coupled with an inimitable and potent pen, challenged the PRI’s hegemony in Mexico and contributed to the historic election he almost lived to celebrate (an elderly Paz died shortly before the historic 1998 election.“The Aztec ritual of 2 October [1968] in the Plaza de Tlatelolco. . . convinced me to abandon the Mexican Foreign Service.”“October 2, 1968 ended the student movement. It also ended an era in thehistory of Mexico.”

  17. The Vienna and German heritage of orthopaedics from the first half of the twentieth century: Adolf Lorenz, Lorenz Böhler, Friedrich Pauwels, Gerhard Küntscher.

    Science.gov (United States)

    Hernigou, Philippe

    2016-05-01

    In the last part of the nineteenth century and beginning of the twentieth century surgeons at the University of Vienna helped transform the practice of surgery. They developed new more effective procedures, analyzed the results of their operations, promoted the emergence and growth of surgical specialties and sought understanding of tissue structure, physiology and pathophysiology. Their efforts made Vienna one of the world's most respected centres for operative treatment, basic and clinical research and surgical education. Two individuals, Adolf Lorenz (1854-1946) and Lorenz Böhler (1885-1973) focused their research and clinical practice on orthopaedics. During the same period in Germany Friedrich Pauwels (1885-1980) founded an orthopaedic institute and an engineering workshop in Aachen in 1913 and rapidly developed a lifelong interest in biomechanical influences: Using these theories, he achieved in 1927 healing of a non-union of the femoral neck by a re-orientation osteotomy, a condition considered to be incurable until this osteotomy and created his famous classification of fracture angles at the hip into Pauwels types I, II and III. The German orthopaedist Gerhard Küntscher (1900-1972) remained the most popular surgeon after the second war with his famous nail.

  18. Veterinary entomology, colonial science and the challenge of tick-borne diseases in South Africa during the late nineteenth and early twentieth centuries.

    Science.gov (United States)

    Brown, K

    2008-12-01

    This article provides an historical overview of developments in veterinary entomology during the late nineteenth and early twentieth centuries. During that period state employed entomologists and veterinary scientists discovered that ticks were responsible for transmitting a number of livestock diseases in South Africa. Diseases such as heartwater, redwater and gallsickness were endemic to the country. They had a detrimental effect on pastoral output, which was a mainstay of the national economy. Then in 1902 the decimating cattle disease East Coast fever arrived making the search for cures or preventatives all the more urgent. Vaccine technologies against tick-borne diseases remained elusive overall and on the basis of scientific knowledge, the South African state recommended regularly dipping animals in chemical solutions to destroy the ticks. Dipping along with quarantines and culls resulted in the eradication of East Coast fever from South Africa in the early 1950s. However, from the 1930s some ticks evolved a resistance to the chemical dips meaning that diseases like redwater were unlikely to be eliminated by that means. Scientists toiled to improve upon existing dipping technologies and also carried out ecological surveys to enhance their ability to predict outbreaks. Over the longer term dipping was not a panacea and ticks continue to present a major challenge to pastoral farming.

  19. [Nutrition sciences in Spain in the second half of the twentieth century: a descriptive bibliometric study of the journal Anales de Bromatologia (1949-1993)].

    Science.gov (United States)

    Bernabeu-Mestre, J; Ureña Alberola, M T; Esplugues Pellicer, J X; Trescastro-López, E M; Galiana-Sánchez, M E; Castelló Botía, I

    2012-11-01

    To analyse the institutionalisation of nutrition sciences in Spain in the second half of the twentieth century, and evaluate the activities of the journal Anales de Bromatología. Descriptive bibliometric study of the original articles. Full names of the authors and the complete article title were recorded. Using key words, each article was assigned by consensus of the researchers to a single main subject in accordance with the thirteen subject areas addressed by the Spanish Society of Bromatology in its meetings. An analysis was conducted of the distribution and trends of general productivity indicators and their characteristics. A total of 917 original articles were published, with a mean of 20.8 papers/year. The subjects for which the highest percentage of articles was recorded were foreign substances in foods, foods of plant origin and nutrition. A total of 874 authors contributed, with a collaboration rate of 2.43 and a transience rate of 70.1%. Distribution of the number of authors per article was close to that indicated by Lotka's law of scientific productivity. The top twelve producers, predominantly women, participated in 49.9% of the articles published. The journal showed low productivity and was of an endogamous nature, with a predominance of authors related to the School of Bromatology in the Faculty of Pharmacy, at the Complutense University. The subjects addressed reflected the demands of the nutrition transition in Spain.

  20. The understanding and operative treatment of cerebral palsy at the turn of the twentieth century: Harvey Cushing's early forays into pediatric neurosurgery.

    Science.gov (United States)

    Dmetrichuk, Jennifer M; Pendleton, Courtney; Ahn, Edward S; Quiñones-Hinojosa, Alfredo

    2011-09-01

    At the turn of the twentieth century, cerebral palsy and its treatment were not well understood, and a variety of treatment modalities were tested with only limited success. Following IRB approval and through the courtesy of the Alan Mason Chesney Archives, we reviewed the Johns Hopkins Hospital surgical files from 1896-1912. Eight patients who received a diagnosis consistent with cerebral palsy and were treated surgically by Dr. Cushing were selected for further analysis and are described here. A total of eight patients underwent operative intervention for treatment of symptoms consistent with cerebral palsy. Of these, seven were male; the mean age was 4.9 years (range, 1.5 to 12). Five patients underwent decompressive craniotomies, one underwent tenotomies, one underwent transection of the spinal nerve roots, and one underwent primary transection of the spinal nerve roots with secondary tenotomies. Four representative cases are reported here. Cushing's contributions to pediatric neuro-oncology have been previously described, but his endeavors in non-oncologic realms remain largely unknown. Although Cushing employed previously described operative approaches for the treatment of cerebral palsy, parents brought their children to him from across the nation, in an era when long distance travel was tedious, and a financial burden. These cases serve to emphasize Cushing's interest in improving patient quality of life, and his broad contributions to pediatric neurosurgery.

  1. Shirley Jackson’s Literary Discourse and the Allegation of Feminism as Socio-Cultural Subversion in Mid-Twentieth Century America

    Directory of Open Access Journals (Sweden)

    Gustavo Vargas Cohen

    2011-12-01

    Full Text Available Shirley Jackson (1916-1965 managed to combine the dual role of being a woman and a writer in mid-twentieth century American society. This article seeks to unravel some of the intricacies behind this brittle balance. Despite and/or because of her condition as mother and professional her literary achievements as a chronicler of the “Age of Anxiety” were laudable and therefore worthy of further investigation. To better understand the historical experience of professional women in that context, a review of post-war US, especially regarding gender roles, ensues not only as historical background but as methodological hotbed for literary analysis. Ms. Jackson’s literary practice helped raise the charges of feminism against her under the allegation of cultural subversion and social sedition. Finally, the question of whether she was indeed a feminist is debated taking intoconsideration her literary discourse, particularly the representations of female characters as discerningly portrayed in her fictional works, correlated to her social and historical milieu.

  2. [Enrico Modigliani and the Institution of maternal assistance: a study of the social factors of illegitimate motherhood during early Twentieth century].

    Science.gov (United States)

    Fano, Valeria

    2016-01-01

    Enrico Modigliani (1877-1931) was an Italian paediatrician of the early Twentieth century whose work anticipated modern concepts of maternal and child health. Convinced of the importance of creating a network of health and social care for children born out-of-wedlock, he began by providing care to single mothers and their babies at his home on Sundays. In 1918, in Rome, he established the Institution for Maternal Assistance, which aim was to provide single mothers with basic health information as well as tools to face their socioeconomic situation. The Opera encouraged breastfeeding and maternal acknowledgement of the child and promoted the establishment of lactation rooms and nurseries within factories. Moreover, women were supported to find a job which was compatible with their situation. In the first five years of activity, over 1,000 unmarried women were assisted; 95% of them acknowledged their children and 52% found a job. The infant mortality rate fell to 11%, which was much lower than the 35% observed at the time among the social classes which Modigliani called the most miserable. This article reviews Modigliani's paper, in which the paediatrician reported the first five years of activity of the Institution of Maternal Assistance and where he largely focused on the social factors surrounding illegitimate motherhood. The paper was structured like a modern scientific report, with photographic documentation and statistical data, and proposed a point of view regarding social inequality which is surprisingly up-to-date.

  3. Evaluation of Surface Air Temperature Change over China and the Globe during the Twentieth Century in IAP AGCM4.0

    Institute of Scientific and Technical Information of China (English)

    DONG Xiao; XUE Feng; ZHANG He; ZENG Qing-Cun

    2012-01-01

    Based on time series and linear trend analysis, the authors evaluated the performance of the fourth gen- eration atmospheric general circulation model developed at the Institute of Atmospheric Physics, Chinese Academy of Sciences (IAP AGCM4.0), in simulating surface air temperature (SAT) during the twentieth century over China and the globe. The numerical experiment is con- ducted by driving the model with the observed sea surface temperature and sea ice. It is shown that IAP AGCM4.0 can simulate the warming trend of the global SAT, with the major wanning regions in the high latitudes of the Northern Hemisphere and the mid-latitudes of the South- ern Hemisphere. While the simulated trend over the whole globe is close to the observation, the model trader- estimates the observed trend over the continents. More- over, the model simulates the spatial distribution of SAT in China, with a bias of approximately -2℃ in eastern China, but with a more serious bias in western China. Compared with the global mean, however, the correlation coefficient between the simulation and observation in China is significantly lower, indicating that there is large uncertainty in simulating regional climate change.

  4. The conquest of vitalism or the eclipse of organicism? The 1930s Cambridge organizer project and the social network of mid-twentieth-century biology.

    Science.gov (United States)

    Peterson, Erik

    2014-06-01

    In the 1930s, two concepts excited the European biological community: the organizer phenomenon and organicism. This essay examines the history of and connection between these two phenomena in order to address the conventional 'rise-and-fall' narrative that historians have assigned to each. Scholars promoted the 'rise-and-fall' narrative in connection with a broader account of the devitalizing of biology through the twentieth century. I argue that while limited evidence exists for the 'fall of the organizer concept' by the 1950s, the organicism that often motivated the organizer work had no concomitant fall--even during the mid-century heyday of molecular biology. My argument is based on an examination of shifting social networks of life scientists from the 1920s to the 1970s, many of whom attended or corresponded with members of the Cambridge Theoretical Biology Club (1932-1938). I conclude that the status and cohesion of these social networks at the micro scale was at least as important as macro-scale conceptual factors in determining the relative persuasiveness of organicist philosophy.

  5. Book Review Imaginary modernity and tradition. Architecture of the twentieth century in Latin America / Reseña del Libro Imaginarios de modernidad y tradición. Arquitectura del siglo XX en América Latina

    Directory of Open Access Journals (Sweden)

    Adolfo Benito Narváez Tijerina

    2016-10-01

    Full Text Available Book Review Imaginary modernity and tradition. Architecture of the twentieth century in Latin America Reseña del Libro Imaginarios de modernidad y tradición. Arquitectura del siglo XX en América Latina. Ettinger, Catherine R. (coord. (2015. Imaginarios de modernidad y tradición. Arquitectura del siglo XX en América Latina. México: Miguel Ángel Porrúa, 259 páginas. ISBN: 978-6074019681.

  6. Microsatellite data analysis for population genetics

    Science.gov (United States)

    Theories and analytical tools of population genetics have been widely applied for addressing various questions in the fields of ecological genetics, conservation biology, and any context where the role of dispersal or gene flow is important. Underlying much of population genetics is the analysis of ...

  7. (Genetic structure of natural populations)

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    Our efforts in the first eight months were concentrated in obtaining a genomic clone of the copper-zinc superoxide dismutase (SOD) in Drosophila melanogaster and other Drosophila species. This we have now successfully accomplished. We seek to understand the role of SOD in radioresistance; how genetic variation in this enzyme is maintained in populations; and relevant aspects of its evolution that may contribute to these goals as well as to an understanding of molecular evolution in general. To accomplish these goals we are undertaking the following experiments: cloning and sequencing of (at least) one F allele, one S allele, and the null allele for SOD; cloning and sequencing SOD from species related to D. melanogaster; and cloning and sequencing the SOD gene from several independently sampled S and F alleles in D. melanogaster. We are also preparing to test the radioprotective effects of SOD. 67 refs.

  8. The Debate about the Origin of Venereal Disease and VD Control in Modern China : Focusing on Shanghai and Beijing in the First Half of the Twentieth Century

    Directory of Open Access Journals (Sweden)

    SIHN Kyuhwan

    2007-06-01

    Full Text Available This paper examines venereal disease(VD control in Shanghai and Beijing in the first half of the twentieth century. It focuses on the debate about the origin of VD in which western doctors stressed the importance of prostitution rather than VD itself. While missionary western doctors approached VD and prostitution from a moral perspective, Chinese western doctors adopted a public health approach. Because Chinese western doctors favored the medium of popular magazines and newspapers to publicize VD and enlighten the public, it is difficult to find their writings on VD in the medical journals such as The National Medical Journal of China(NMJ. Therefore, Chinese western doctors had not been indifferent to VD as previously thought. Common people preferred the black market to the open clinic, and abused salvarsan to cure VD in secret. This suggests the sensitive nature of VD as a disease that degrades personal honor. VD control varied depending on the perspective of the origin of VD and the prostitution, and measures taken. While moralists in the debate upheld a position to abolish licensed prostitution, public health enthusiasts propped up licensed prostitution. VD control in Shanghai and Beijing displays a striking contrast. In Shanghai, the power to control VD and prostitutes were separated. The Shanghai Municipal Council(SMC, French Municipal Council(FMC, and Shanghai Municipality(SM did not cooperate in the control of VD and prostitutes. When SMC devoted its energies to abolish licensed prostitution, FMC and SM enjoyed prostitute's taxes. The Beiping Municipality(1928-1937 practiced multiple forms of control patterns and targets of VD. They adopted a bifurcated policy regarding VD. The targets of diagnosis were divided into prostitute, pregnant women, and normal citizen. The range of the reach of the health administration in Beiping Municipality was gradually magnified.

  9. Avalanche related damage potential - changes of persons and mobile values since the mid-twentieth century, case study Galtür

    Directory of Open Access Journals (Sweden)

    M. Keiler

    2005-01-01

    Full Text Available When determining risk related to natural hazard processes, many studies neglect the investigations of the damage potential or are limited to the assessment of immobile values like buildings. However, persons as well as mobile values form an essential part of the damage potential. Knowledge of the maximum number of exposed persons in an endangered area is of great importance for elaborating evacuation plans and immediate measures in case of catastrophes. In addition, motor vehicles can also be highly damaged, as was shown by the analysis of avalanche events. With the removal of mobile values in time as a preventive measure this kind of damage can be minimised. This study presents a method for recording the maximum number of exposed persons and monetarily assessing motor vehicles in the municipality of Galtür (Tyrol, Austria. Moreover, general developments of the damage potential due to significant socio-economic changes since the mid-twentieth century are pointed out in the study area. The present situation of the maximum number of persons and mobile values in the official avalanche hazard zones of the municipality is described in detail. Information on the number of persons is derived of census data, tourism and employment statistics. During the winter months, a significant increase overlaid by strong short-term fluctuation in the number of persons can be noted. These changes result from a higher demand of tourism related manpower as well as from varying occupancy rates. The number of motor vehicles in endangered areas is closely associated to the number of exposed persons. The potential number of motor vehicles is investigated by means of mapping, statistics on the stock of motor vehicles and the density distribution. Diurnal and seasonal fluctuations of the investigated damage potential are pointed out. The recording of the number of persons and mobile values in endangered areas is vital for any disaster management.

  10. Microbial diversity - insights from population genetics

    NARCIS (Netherlands)

    Mes, T.H.M.

    2008-01-01

    Although many environmental microbial populations are large and genetically diverse, both the level of diversity and the extent to which it is ecologically relevant remain enigmatic. Because the effective (or long-term) population size, Ne, is one of the parameters that determines population genetic

  11. Exploring the impact of agriculture on nitrogen and phosphorus biogeochemistry in global rivers during the twentieth century (Invited)

    Science.gov (United States)

    Bouwman, L.; Beusen, A.; Van Beek, L. P.

    2013-12-01

    Nutrients are transported from land to sea through the continuum formed by soils, groundwater, riparian zones, floodplains, streams, rivers, lakes, and reservoirs. The hydrology, ecology and biogeochemical processing in each of these components are strongly coupled and result in retention of a significant fraction of the nutrients transported. This paper analyzes the global changes in nutrient biogeochemical processes and retention in rivers during the past century (1900-2000); this period encompasses dramatic increases in human population and economic human activities including agriculture that have resulted in major changes in land use, nutrient use in agriculture, wastewater flows and human interventions in the hydrology (1). We use the hydrological PCR-GLOBWB model (2) for the period 1900-2000, including climate variability and the history of dam construction and land use conversion. Global agricultural and natural N and P soil budgets for the period 1900-2000 are the starting point to simulate nutrient flows from the soil via surface runoff and leaching through the groundwater system and riparian zones. In-stream processes are described with the nutrient spiraling concept. In the period 1900-2000, the global soil N budget surplus (inputs minus withdrawal in harvested crops) for agricultural and natural ecosystems increased from 118 to 202 Tg yr-1, and the global P budget increased from Philosophical Transactions of the Royal Society B: Biological Sciences. 2013;368(20130112). 2. Van Beek LPH, Wada Y, Bierkens MFP. Global monthly water stress: 1. Water balance and water availability. Water Resour Res. 2011;47(7):W07517.

  12. Conservation genetics of managed ungulate populations

    Science.gov (United States)

    Scribner, Kim T.

    1993-01-01

    Natural populations of many species are increasingly impacted by human activities. Perturbations are particularly pronunced for large ungulates due in part to sport and commercial harvest, to reductions and fragmentation of native habitat, and as the result of reintroductions. These perturbations affect population size, sex and age composition, and population breeding structure, and as a consequence affect the levels and partitioning of genetic variation. Three case histories highlighting long-term ecological genetic research on mule deer Odocoileus hemionus (Rafinesque, 1817), white-tailed deer O. virginianus (Zimmermann, 1780), and Alpine ibex Capra i. ibex Linnaeus, 1758 are presented. Joint examinations of population ecological and genetic data from several populations of each species reveal: (1) that populations are not in genetic equilibrium, but that allele frequencies and heterozygosity change dramatically over time and among cohorts produced in successive years, (2) populations are genetically structured over short and large geographic distances reflecting local breeding structure and patterns of gene flow, respectively; however, this structure is quite dynamic over time, due in part to population exploitation, and (3) restocking programs are often undertaken with small numbers of founding individuals resulting in dramatic declines in levels of genetic variability and increasing levels of genetic differentiation among populations due to genetic drift. Genetic characteristics have and will continue to provide valuable indirect sources of information relating enviromental and human perturbations to changes in population processes.

  13. Genetic diversity and population structure in Meconopsis ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-05-24

    May 24, 2010 ... including the populations distributed in same location together in every group. ... Key words: Meconopsis quintuplinervia Regel, genetic diversity, random amplified ..... in its original center, and Banma population located in ...

  14. Gene finding in genetically isolated populations

    NARCIS (Netherlands)

    P. Heutink (Peter); B.A. Oostra (Ben)

    2002-01-01

    textabstractThe struggle to identify susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. One approach that has gained considerable interest is to focus on genetically isolated populations rather than on the general population. There rema

  15. Understanding of Genetic Information in Higher Secondary Students in Northeast India and the Implications for Genetics Education

    Science.gov (United States)

    Chattopadhyay, Ansuman

    2005-01-01

    Since the work of Watson and Crick in the mid-1950s, the science of genetics has become increasingly molecular. The development of recombinant DNA technologies by the agricultural and pharmaceutical industries led to the introduction of genetically modified organisms (GMOs). By the end of the twentieth century, reports of animal cloning and recent…

  16. Twentieth Century Internationalism in Law

    DEFF Research Database (Denmark)

    Spiermann, Ole

    2007-01-01

    against a background coloured by national legal traditions. International lawyers did not overcome the optimist and evolutionary tradition based on the assumption that international law is but an ever closer approximation of national legal systems; nor did lawyers escape the fl ip side of this tradition...

  17. A Twentieth Century Morality Play.

    Science.gov (United States)

    Pallenik, Michael

    1978-01-01

    Criticizes Erving Goffman's theory that human gestures express cultural assumptions which, in turn, legitimize social structure. Contends that Goffman blurs the distinction between his own observations as a social scientist and the interpretations of behavior by people within social situations. (JMF)

  18. Genetic variation among white croaker populations

    Science.gov (United States)

    Han, Zhiqiang; Gao, Tianxiang; Zhuang, Zhimeng; Tang, Qisheng

    2008-02-01

    To investigate the genetic structures and differentiation of different wild populations of white croaker ( Pennahia argentata), horizontal starch gel electrophoresis was performed on 133 individuals collected from five different locations in China and Japan. The eleven enzyme systems revealed 15 loci, of which eleven were polymorphic. The percentage of polymorphic loci of white croaker populations varied from 6.67% to 53.33%; the mean observed and expected heterozygosity ranged from 0.0033 to 0.0133 and 0.0032 to 0.0191, respectively. The expected heterozygosity revealed a low genetic variability for white croaker in comparison with other marine fishes. The genetic distances between populations ranged from 0.00005 to 0.00026. A weak differentiation was observed within each clade and between clades; and no significant differences in gene frequencies among populations were observed in white croaker. Among the five populations, three Chinese populations showed more genetic diversity than that in Japanese populations.

  19. Modeling the potential contribution of land cover changes to the late twentieth century Sahel drought using a regional climate model: impact of lateral boundary conditions

    Science.gov (United States)

    Wang, Guiling; Yu, Miao; Xue, Yongkang

    2016-12-01

    This paper investigates the potential impact of "idealized-but-realistic" land cover degradation on the late twentieth century Sahel drought using a regional climate model (RCM) driven with lateral boundary conditions (LBCs) from three different sources, including one re-analysis data and two global climate models (GCMs). The impact of land cover degradation is quantified based on a large number of control-and-experiment pairs of simulations, where the experiment features a degraded land cover relative to the control. Two different approaches of experimental design are tested: in the 1st approach, the RCM land cover degradation experiment shares the same LBCs as the corresponding RCM control, which can be derived from either reanalysis data or a GCM; with the 2nd approach, the LBCs for the RCM control are derived from a GCM control, and the LBCs for the RCM land cover degradation experiment are derived from a corresponding GCM land cover degradation experiment. When the 1st approach is used, results from the RCM driven with the three different sources of LBCs are generally consistent with each other, indicating robustness of the model response against LBCs; when the 2nd approach is used, the RCM results show strong sensitivity to the source of LBCs and the response in the RCM is dominated by the response of the driving GCMs. The spatiotemporal pattern of the precipitation response to land cover degradation as simulated by RCM using the 1st approach closely resembles that of the observed historical changes, while results from the GCMs and the RCM using the 2nd approach bear less similarity to observations. Compared with the 1st approach, the 2nd approach has the advantage of capturing the impact on large scale circulation, but has the disadvantage of being influenced by the GCMs' internal variability and any potential erroneous response of the driving GCMs to land degradation. The 2nd approach therefore requires a large ensemble to reduce the uncertainties derived

  20. What Use Is Population Genetics?

    Science.gov (United States)

    Charlesworth, Brian

    2015-07-01

    The Genetic Society of America's Thomas Hunt Morgan Medal is awarded to an individual GSA member for lifetime achievement in the field of genetics. For over 40 years, 2015 recipient Brian Charlesworth has been a leader in both theoretical and empirical evolutionary genetics, making substantial contributions to our understanding of how evolution acts on genetic variation. Some of the areas in which Charlesworth's research has been most influential are the evolution of sex chromosomes, transposable elements, deleterious mutations, sexual reproduction, and life history. He also developed the influential theory of background selection, whereby the recurrent elimination of deleterious mutations reduces variation at linked sites, providing a general explanation for the correlation between recombination rate and genetic variation.

  1. Genetic drift of HIV populations in culture.

    Directory of Open Access Journals (Sweden)

    Yegor Voronin

    2009-03-01

    Full Text Available Populations of Human Immunodeficiency Virus type 1 (HIV-1 undergo a surprisingly large amount of genetic drift in infected patients despite very large population sizes, which are predicted to be mostly deterministic. Several models have been proposed to explain this phenomenon, but all of them implicitly assume that the process of virus replication itself does not contribute to genetic drift. We developed an assay to measure the amount of genetic drift for HIV populations replicating in cell culture. The assay relies on creation of HIV populations of known size and measurements of variation in frequency of a neutral allele. Using this assay, we show that HIV undergoes approximately ten times more genetic drift than would be expected from its population size, which we defined as the number of infected cells in the culture. We showed that a large portion of the increase in genetic drift is due to non-synchronous infection of target cells. When infections are synchronized, genetic drift for the virus is only 3-fold higher than expected from its population size. Thus, the stochastic nature of biological processes involved in viral replication contributes to increased genetic drift in HIV populations. We propose that appreciation of these effects will allow better understanding of the evolutionary forces acting on HIV in infected patients.

  2. Genetics of autoimmune diseases: insights from population genetics.

    Science.gov (United States)

    Ramos, Paula S; Shedlock, Andrew M; Langefeld, Carl D

    2015-11-01

    Human genetic diversity is the result of population genetic forces. This genetic variation influences disease risk and contributes to health disparities. Autoimmune diseases (ADs) are a family of complex heterogeneous disorders with similar underlying mechanisms characterized by immune responses against self. Collectively, ADs are common, exhibit gender and ethnic disparities, and increasing incidence. As natural selection is an important influence on human genetic variation, and immune function genes are enriched for signals of positive selection, it is thought that the prevalence of AD risk alleles seen in different population is partially the result of differing selective pressures (for example, due to pathogens). With the advent of high-throughput technologies, new analytical methodologies and large-scale projects, evidence for the role of natural selection in contributing to the heritable component of ADs keeps growing. This review summarizes the genetic regions associated with susceptibility to different ADs and concomitant evidence for selection, including known agents of selection exerting selective pressure in these regions. Examples of specific adaptive variants with phenotypic effects are included as an evidence of natural selection increasing AD susceptibility. Many of the complexities of gene effects in different ADs can be explained by population genetics phenomena. Integrating AD susceptibility studies with population genetics to investigate how natural selection has contributed to genetic variation that influences disease risk will help to identify functional variants and elucidate biological mechanisms. As such, the study of population genetics in human population holds untapped potential for elucidating the genetic causes of human disease and more rapidly focusing to personalized medicine.

  3. Genetic composition of captive panda population.

    Science.gov (United States)

    Yang, Jiandong; Shen, Fujun; Hou, Rong; Da, Yang

    2016-10-03

    A major function of the captive panda population is to preserve the genetic diversity of wild panda populations in their natural habitats. Understanding the genetic composition of the captive panda population in terms of genetic contributions from the wild panda populations provides necessary knowledge for breeding plans to preserve the genetic diversity of the wild panda populations. The genetic contributions from different wild populations to the captive panda population were highly unbalanced, with Qionglai accounting for 52.2 % of the captive panda gene pool, followed by Minshan with 21.5 %, Qinling with 10.6 %, Liangshan with 8.2 %, and Xiaoxiangling with 3.6 %, whereas Daxiangling, which had similar population size as Xiaoxiangling, had no genetic representation in the captive population. The current breeding recommendations may increase the contribution of some small wild populations at the expense of decreasing the contributions of other small wild populations, i.e., increasing the Xiaoxiangling contribution while decreasing the contribution of Liangshan, or sharply increasing the Qinling contribution while decreasing the contributions of Xiaoxiangling and Liangshan, which were two of the three smallest wild populations and were already severely under-represented in the captive population. We developed three habitat-controlled breeding plans that could increase the genetic contributions from the smallest wild populations to 6.7-11.2 % for Xiaoxiangling, 11.5-12.3 % for Liangshan and 12.9-20.0 % for Qinling among the offspring of one breeding season while reducing the risk of hidden inbreeding due to related founders from the same habitat undetectable by pedigree data. The three smallest wild panda populations of Daxiangling, Xiaoxiangling and Liangshan either had no representation or were severely unrepresented in the current captive panda population. By incorporating the breeding goal of increasing the genetic contributions from the smallest wild

  4. Ocean currents help explain population genetic structure

    Science.gov (United States)

    White, Crow; Selkoe, Kimberly A.; Watson, James; Siegel, David A.; Zacherl, Danielle C.; Toonen, Robert J.

    2010-01-01

    Management and conservation can be greatly informed by considering explicitly how environmental factors influence population genetic structure. Using simulated larval dispersal estimates based on ocean current observations, we demonstrate how explicit consideration of frequency of exchange of larvae among sites via ocean advection can fundamentally change the interpretation of empirical population genetic structuring as compared with conventional spatial genetic analyses. Both frequency of larval exchange and empirical genetic difference were uncorrelated with Euclidean distance between sites. When transformed into relative oceanographic distances and integrated into a genetic isolation-by-distance framework, however, the frequency of larval exchange explained nearly 50 per cent of the variance in empirical genetic differences among sites over scales of tens of kilometres. Explanatory power was strongest when we considered effects of multiple generations of larval dispersal via intermediary locations on the long-term probability of exchange between sites. Our results uncover meaningful spatial patterning to population genetic structuring that corresponds with ocean circulation. This study advances our ability to interpret population structure from complex genetic data characteristic of high gene flow species, validates recent advances in oceanographic approaches for assessing larval dispersal and represents a novel approach to characterize population connectivity at small spatial scales germane to conservation and fisheries management. PMID:20133354

  5. Population genetics of African ungulates

    DEFF Research Database (Denmark)

    Lorenzen, Eline

    Molecular genetic techniques were used to gain insights into the evolutionary forces that have shaped the present day diversity of African savannah ungu-lates, which constitute the most species-rich mega faunal assemblage on earth. The studies included in this thesis represent individual species......-specific data sets, which are used to elucidate evolutionary processes of importance to the savannah ungulate community. Patterns of DNA variation were analyzed to assess the genetic signatures of Pleistocene refugia and investigate aspects of speciation, intraspecific structuring, hybridization, and historic...

  6. Microbial diversity--insights from population genetics.

    Science.gov (United States)

    Mes, Ted H M

    2008-01-01

    Although many environmental microbial populations are large and genetically diverse, both the level of diversity and the extent to which it is ecologically relevant remain enigmatic. Because the effective (or long-term) population size, N(e), is one of the parameters that determines population genetic diversity, tests and simulations that assume selectively neutral mutations may help to identify the processes that have shaped microbial diversity. Using ecologically important genes, tests of selective neutrality suggest that adaptive as well as non-adaptive types of selection act and that departure from neutrality may be widespread or restricted to small groups of genotypes. Population genetic simulations using population sizes between 10(3) and 10(7) suggest extremely high levels of microbial diversity in environments that sustain large populations. However, census and effective population sizes may differ considerably, and because we know nothing of the evolutionary history of environmental microbial populations, we also have no idea what N(e) of environmental populations is. On the one hand, this reflects our ignorance of the microbial world. On the other hand, the tests and simulations illustrate interactions between microbial diversity and microbial population genetics that should inform our thinking in microbial ecology. Because of the different views on microbial diversity across these disciplines, such interactions are crucial if we are to understand the role of genes in microbial communities.

  7. Carbon balance of the terrestrial biosphere in the twentieth century: analyses of CO2, climate and land use effects with four process-based ecosystem models

    Science.gov (United States)

    McGuire, A.D.; Sitch, S.; Clein, J.S.; Dargaville, R.; Esser, G.; Foley, J.; Heimann, Martin; Joos, F.; Kaplan, J.; Kicklighter, D.W.; Meier, R.A.; Melillo, J.M.; Moore, B.; Prentice, I.C.; Ramankutty, N.; Reichenau, T.; Schloss, A.; Tian, H.; Williams, L.J.; Wittenberg, U.

    2001-01-01

    The concurrent effects of increasing atmospheric CO2 concentration, climate variability, and cropland establishment and abandonment on terrestrial carbon storage between 1920 and 1992 were assessed using a standard simulation protocol with four process-based terrestrial biosphere models. Over the long-term(1920–1992), the simulations yielded a time history of terrestrial uptake that is consistent (within the uncertainty) with a long-term analysis based on ice core and atmospheric CO2 data. Up to 1958, three of four analyses indicated a net release of carbon from terrestrial ecosystems to the atmosphere caused by cropland establishment. After 1958, all analyses indicate a net uptake of carbon by terrestrial ecosystems, primarily because of the physiological effects of rapidly rising atmospheric CO2. During the 1980s the simulations indicate that terrestrial ecosystems stored between 0.3 and 1.5 Pg C yr−1, which is within the uncertainty of analysis based on CO2 and O2 budgets. Three of the four models indicated (in accordance with O2 evidence) that the tropics were approximately neutral while a net sink existed in ecosystems north of the tropics. Although all of the models agree that the long-term effect of climate on carbon storage has been small relative to the effects of increasing atmospheric CO2 and land use, the models disagree as to whether climate variability and change in the twentieth century has promoted carbon storage or release. Simulated interannual variability from 1958 generally reproduced the El Niño/Southern Oscillation (ENSO)-scale variability in the atmospheric CO2 increase, but there were substantial differences in the magnitude of interannual variability simulated by the models. The analysis of the ability of the models to simulate the changing amplitude of the seasonal cycle of atmospheric CO2 suggested that the observed trend may be a consequence of CO2 effects, climate variability, land use changes, or a combination of these effects

  8. Great ape genetic diversity and population history

    DEFF Research Database (Denmark)

    Prado-Martinez, Javier; Sudmant, Peter H; Kidd, Jeffrey M

    2013-01-01

    Most great ape genetic variation remains uncharacterized; however, its study is critical for understanding population history, recombination, selection and susceptibility to disease. Here we sequence to high coverage a total of 79 wild- and captive-born individuals representing all six great ape...... species and seven subspecies and report 88.8 million single nucleotide polymorphisms. Our analysis provides support for genetically distinct populations within each species, signals of gene flow, and the split of common chimpanzees into two distinct groups: Nigeria-Cameroon/western and central....../eastern populations. We find extensive inbreeding in almost all wild populations, with eastern gorillas being the most extreme. Inferred effective population sizes have varied radically over time in different lineages and this appears to have a profound effect on the genetic diversity at, or close to, genes in almost...

  9. Population Structure and Genotype–Phenotype Associations in a Collection of Oat Landraces and Historic Cultivars

    Science.gov (United States)

    Winkler, Louisa R.; Michael Bonman, J.; Chao, Shiaoman; Admassu Yimer, B.; Bockelman, Harold; Esvelt Klos, Kathy

    2016-01-01

    Population structure and genetic architecture of phenotypic traits in oat (Avena sativa L.) remain relatively under-researched compared to other small grain species. This study explores the historic context of current elite germplasm, including phenotypic and genetic characterization, with a particular focus on identifying under-utilized areas. A diverse panel of cultivated oat accessions was assembled from the USDA National Small Grains Collection to represent a gene pool relatively unaffected by twentieth century breeding activity and unlikely to have been included in recent molecular studies. The panel was genotyped using an oat iSelect 6K beadchip SNP array. The final dataset included 759 unique individuals and 2,715 polymorphic markers. Some population structure was apparent, with the first three principal components accounting for 38.8% of variation and 73% of individuals belonging to one of three clusters. One cluster with high genetic distinctness appears to have been largely overlooked in twentieth century breeding. Classification and phenotype data provided by the Germplasm Resources Information Network were evaluated for their relationship to population structure. Of the structuring variables evaluated, improvement status (cultivar or landrace) was relatively unimportant, indicating that landraces and cultivars included in the panel were all sampled from a similar underlying population. Instead, lemma color and region of origin showed the strongest explanatory power. An exploratory association mapping study of the panel using a subset of 2,588 mapped markers generated novel indications of genomic regions associated with awn frequency, kernels per spikelet, lemma color, and panicle type. Further results supported previous findings of loci associated with barley yellow dwarf virus tolerance, crown rust (caused by Puccinia coronata f. sp. avenae) resistance, days to anthesis, and growth habit (winter/spring). In addition, two novel loci were identified for

  10. Population structure and genotype-phenotype associations in a collection of oat landraces and historic cultivars

    Directory of Open Access Journals (Sweden)

    Louisa Rosemarie Winkler

    2016-07-01

    Full Text Available Population structure and genetic architecture of phenotypic traits in oat (Avena sativa L. remain relatively under-researched compared to other small grain species. This study explores the historic context of current elite germplasm, including phenotypic and genetic characterization, with a particular focus on identifying under-utilized areas. A diverse panel of cultivated oat accessions was assembled from the USDA National Small Grains Collection to represent a gene pool relatively unaffected by twentieth century breeding activity and unlikely to have been included in recent molecular studies. The panel was genotyped using an oat iSelect 6K beadchip SNP array. The final dataset included 759 unique individuals and 2,715 polymorphic markers. Some population structure was apparent; with the first three principal components accounting for 38.8% of variation and 73% of individuals belonging to one of three clusters. One cluster with high genetic distinctness appears to have been largely overlooked in twentieth century breeding. Classification and phenotype data provided by the Germplasm Resources Information Network were evaluated for their relationship to population structure. Of the structuring variables evaluated, improvement status (cultivar or landrace was relatively unimportant, indicating that landraces and cultivars included in the panel were all sampled from a similar underlying population. Instead, lemma color and region of origin showed the strongest explanatory power. An exploratory association mapping study of the panel using a subset of 2,588 mapped markers generated novel indications of genomic regions associated with awn frequency, kernels per spikelet, lemma color and panicle type. Further results supported previous findings of loci associated with barley yellow dwarf virus tolerance, crown rust (caused by Puccinia coronata f. sp. avenae resistance, days to anthesis and growth habit (winter/spring. In addition, two novel loci were

  11. The genetic structure of the Swedish population.

    Directory of Open Access Journals (Sweden)

    Keith Humphreys

    Full Text Available Patterns of genetic diversity have previously been shown to mirror geography on a global scale and within continents and individual countries. Using genome-wide SNP data on 5174 Swedes with extensive geographical coverage, we analyzed the genetic structure of the Swedish population. We observed strong differences between the far northern counties and the remaining counties. The population of Dalarna county, in north middle Sweden, which borders southern Norway, also appears to differ markedly from other counties, possibly due to this county having more individuals with remote Finnish or Norwegian ancestry than other counties. An analysis of genetic differentiation (based on pairwise F(st indicated that the population of Sweden's southernmost counties are genetically closer to the HapMap CEU samples of Northern European ancestry than to the populations of Sweden's northernmost counties. In a comparison of extended homozygous segments, we detected a clear divide between southern and northern Sweden with small differences between the southern counties and considerably more segments in northern Sweden. Both the increased degree of homozygosity in the north and the large genetic differences between the south and the north may have arisen due to a small population in the north and the vast geographical distances between towns and villages in the north, in contrast to the more densely settled southern parts of Sweden. Our findings have implications for future genome-wide association studies (GWAS with respect to the matching of cases and controls and the need for within-county matching. We have shown that genetic differences within a single country may be substantial, even when viewed on a European scale. Thus, population stratification needs to be accounted for, even within a country like Sweden, which is often perceived to be relatively homogenous and a favourable resource for genetic mapping, otherwise inferences based on genetic data may lead to

  12. The geometry of population genetics

    CERN Document Server

    Akin, Ethan

    1979-01-01

    The differential equations which model the action of selection and recombination are nonlinear equations which are impossible to It is even difficult to describe in general the solve explicitly. Recently, Shahshahani began using qualitative behavior of solutions. differential geometry to study these equations [28]. with this mono­ graph I hope to show that his ideas illuminate many aspects of pop­ ulation genetics. Among these are his proof and clarification of Fisher's Fundamental Theorem of Natural Selection and Kimura's Maximum Principle and also the effect of recombination on entropy. We also discover the relationship between two classic measures of 2 genetic distance: the x measure and the arc-cosine measure. There are two large applications. The first is a precise definition of the biological concept of degree of epistasis which applies to general (i.e. frequency dependent) forms of selection. The second is the unexpected appearance of cycling. We show that cycles can occur in the two-locus-two-allele...

  13. Cárie dentária e flúor: uma relação do século XX Dental caries and fluorine: a twentieth century relation

    Directory of Open Access Journals (Sweden)

    Paulo Capel Narvai

    2000-01-01

    Full Text Available No início do século XX a cárie dentária era um problema de saúde pública, na maior parte do planeta. As populações conviviam com infecção, dor, sofrimento e mutilação. A descoberta do efeito preventivo do flúor o transformou, ao longo do século, no principal agente utilizado no enfrentamento da doença em todo o mundo. Em vários países e também no Brasil produtos fluorados têm sido apontados como os principais responsáveis pelo declínio observado na prevalência da cárie. No Brasil, estudos pioneiros realizados nos anos 50 e 60 corroboraram a eficácia preventiva da fluoretação das águas. No período 1986-1996, com 42% da população recebendo água fluoretada, a queda na prevalência da cárie entre crianças de 12 anos de idade foi de 53%. Além da água fluoretada também os dentifrícios são, no presente, amplamente utilizados como veículos para uso do flúor em saúde pública. Neste artigo são abordados aspectos históricos do emprego de flúor, algumas características epidemiológicas da cárie dentária no Brasil, e as perspectivas da continuidade do uso de produtos fluorados nas próximas décadas.In the early of Twentieth Century, dental caries were a big public health problem around world. Infection, pain, suffering and mutilation reached all people. The discovering of preventive effect of fluorine became them, through the Century, the main agent in fighting to disease worldwide. In various countries, including Brazil, fluoridated products have been pointed as main causes for dental caries prevalence decline. Also in Brazil, at the 50s and 60s, the preventive effect of water fluoridation was ratified for some pioneer studies. For the period 1986-1996 epidemiological data shown a significant reduction of 53% in the DMF-T index value at 12-years-old schoolchildren. Water and dentifrices are largely used as vehicle for fluoride in public health actions. In Brazil 42% of population has access to fluoridated

  14. Population Dynamics of Genetic Regulatory Networks

    Science.gov (United States)

    Braun, Erez

    2005-03-01

    Unlike common objects in physics, a biological cell processes information. The cell interprets its genome and transforms the genomic information content, through the action of genetic regulatory networks, into proteins which in turn dictate its metabolism, functionality and morphology. Understanding the dynamics of a population of biological cells presents a unique challenge. It requires to link the intracellular dynamics of gene regulation, through the mechanism of cell division, to the level of the population. We present experiments studying adaptive dynamics of populations of genetically homogeneous microorganisms (yeast), grown for long durations under steady conditions. We focus on population dynamics that do not involve random genetic mutations. Our experiments follow the long-term dynamics of the population distributions and allow to quantify the correlations among generations. We focus on three interconnected issues: adaptation of genetically homogeneous populations following environmental changes, selection processes on the population and population variability and expression distributions. We show that while the population exhibits specific short-term responses to environmental inputs, it eventually adapts to a robust steady-state, largely independent of external conditions. Cycles of medium-switch show that the adapted state is imprinted in the population and that this memory is maintained for many generations. To further study population adaptation, we utilize the process of gene recruitment whereby a gene naturally regulated by a specific promoter is placed under a different regulatory system. This naturally occurring process has been recognized as a major driving force in evolution. We have recruited an essential gene to a foreign regulatory network and followed the population long-term dynamics. Rewiring of the regulatory network allows us to expose their complex dynamics and phase space structure.

  15. Gene finding in genetically isolated populations.

    Science.gov (United States)

    Heutink, Peter; Oostra, Ben A

    2002-10-01

    The struggle to identify susceptibility genes for complex disorders has stimulated geneticists to develop new approaches. One approach that has gained considerable interest is to focus on genetically isolated populations rather than on the general population. There remains much controversy and theoretical debate over the feasibility and advantages of such populations, but recent results speak in favor of the feasibility of this approach, and will be reviewed here.

  16. Population genetics and benefit sharing.

    Science.gov (United States)

    Knoppers, B M

    2000-01-01

    The majority of international or national guidelines, specific to human genetics concentrate on actual or potential clinical applications. In contrast, the Ethics Committee of the Human Genome Organisation (HUGO) attempts to provide guidance to the bench scientists engaged in fundamental research in genomics prior to any clinical applications. Often confused as constituting the Human Genome Project (HGP) itself, HUGO's (Human Genome Organization) ultimate goal is to assist in the worldwide collaboration underpinning the HGP. It is an international organisation with 1,229 members in approximately 60 countries. The Ethics Committee is one of HUGO's six international advisory committees. Composed of experts from a number of countries and disciplines, the HUGO Ethics Committee promotes discussion and understanding of social, legal, and ethical issues as they relate to the conduct of, and knowledge derived from, the Genome Initiative. Currently, it has 13 members from 11 difference countries. It has produced statements on the conduct of genetic research, on cloning, and, has most recently presented a 'Statement on Benefit-Sharing', April 11, 2000. The Intellectual Property Committee of HUGO has been active in the controversial area of patenting. The issue of benefit-sharing is one that has its source in the mandate of both committees. How to avoid both commodification of the person through payment for access to DNA and biopiracy with no return to benefits to the families or community? While patents are a legitimate form of recognition for innovation, there seems to be no therapeutic exception to some of its stringent rules and the 'morality' exclusion has lain dormant. The HUGO 'Statement on Benefit-Sharing' examines the issues of defining community, common heritage, distributive justice and solidarity before arriving at its conclusions in benefit-sharing. This communication reviews some of these issues.

  17. 'Sunless lives': district nurses' and journalists' co-construction of the 'sick poor' as a vulnerable population in early twentieth-century New Zealand.

    Science.gov (United States)

    Wood, Pamela J; Arcus, Kerri

    2012-10-01

    Portrayals of vulnerable groups in public media, government reports and professional accounts tend, by definition, to focus on their deficits in order to identify need and shape appropriate health care responses. This article within the cultural history of nursing considers a different construction of one vulnerable group in the past, the 'sick poor' in early 20th-century New Zealand. The research analysed primary historical sources that offered rich descriptions of the sick poor, drawn from one major daily newspaper and the country's professional nursing journal, 1900-1920. The article argues that in co-constructing the sick poor as a vulnerable group, district nurses and journalists primarily used the trope of 'sunless lives'. However, they also constructed them as resourceful, resilient and determined. This article offers the construction of the sick poor by district nurses and journalists in early 20th-century New Zealand as an example of a more nuanced construction that goes beyond a one-dimensional portrayal of vulnerability.

  18. Philosophy of race meets population genetics.

    Science.gov (United States)

    Spencer, Quayshawn

    2015-08-01

    In this paper, I respond to four common semantic and metaphysical objections that philosophers of race have launched at scholars who interpret recent human genetic clustering results in population genetics as evidence for biological racial realism. I call these objections 'the discreteness objection', 'the visibility objection', 'the very important objection', and 'the objectively real objection.' After motivating each objection, I show that each one stems from implausible philosophical assumptions about the relevant meaning of 'race' or the nature of biological racial realism. In order to be constructive, I end by offering some advice for how we can productively critique attempts to defend biological racial realism based on recent human genetic clustering results. I also offer a clarification of the relevant human-population genetic research.

  19. The population genetics of evolutionary rescue.

    Directory of Open Access Journals (Sweden)

    H Allen Orr

    2014-08-01

    Full Text Available Evolutionary rescue occurs when a population that is threatened with extinction by an environmental change adapts to the change sufficiently rapidly to survive. Here we extend the mathematical theory of evolutionary rescue. In particular, we model evolutionary rescue to a sudden environmental change when adaptation involves evolution at a single locus. We consider adaptation using either new mutations or alleles from the standing genetic variation that begin rare. We obtain several results: i the total probability of evolutionary rescue from either new mutation or standing variation; ii the conditions under which rescue is more likely to involve a new mutation versus an allele from the standing genetic variation; iii a mathematical description of the U-shaped curve of total population size through time, conditional on rescue; and iv the time until the average population size begins to rebound as well as the minimal expected population size experienced by a rescued population. Our analysis requires taking into account a subtle population-genetic effect (familiar from the theory of genetic hitchhiking that involves "oversampling" of those lucky alleles that ultimately sweep to high frequency. Our results are relevant to conservation biology, experimental microbial evolution, and medicine (e.g., the dynamics of antibiotic resistance.

  20. The Genetic Deafness in Chinese Population

    Institute of Scientific and Technical Information of China (English)

    LIU Xuezhong; Ouyang Xiaomei; Denise Yan

    2006-01-01

    Deafness is an etiologically heterogeneous trait with many known genetic, environmental causes or a combination thereof. The identification of more than 120 independent genes for deafness has provided profound new insights into the pathophysiology of hearing. However, recent findings indicate that a large proportion of both syndromic and nonsyndromic forms of deafness in Chinese population are caused by a small number of mutations.This review is focused on syndromic and nonsyndromic deafness as well as on the latest information linking inherited mitochondrial pathologies to a variety of etiologies of sensorineural deafness in Chinese population. Better understanding of the genetic causes of deafness in Chinese population is important for accurate genetics counseling and early diagnosis for timely intervention and treatment options.

  1. Genetic Structure of the Spanish Population

    Directory of Open Access Journals (Sweden)

    Gutiérrez Marta

    2010-05-01

    Full Text Available Abstract Background Genetic admixture is a common caveat for genetic association analysis. Therefore, it is important to characterize the genetic structure of the population under study to control for this kind of potential bias. Results In this study we have sampled over 800 unrelated individuals from the population of Spain, and have genotyped them with a genome-wide coverage. We have carried out linkage disequilibrium, haplotype, population structure and copy-number variation (CNV analyses, and have compared these estimates of the Spanish population with existing data from similar efforts. Conclusions In general, the Spanish population is similar to the Western and Northern Europeans, but has a more diverse haplotypic structure. Moreover, the Spanish population is also largely homogeneous within itself, although patterns of micro-structure may be able to predict locations of origin from distant regions. Finally, we also present the first characterization of a CNV map of the Spanish population. These results and original data are made available to the scientific community.

  2. Genetic epidemiology of familial aggregation of cancer.

    Science.gov (United States)

    Schneider, N R; Williams, W R; Chaganti, R S

    1986-01-01

    Literature pertaining to genetic epidemiological studies of familial cancer has been reviewed from a historical perspective. Although interest in the question of heritability of cancer was extant at least as early as the beginning of the nineteenth century, early investigators were unable to produce consistent and meaningful evidence pertaining to the issue because of unsystematic methods of data collection and inadequate methods of data analysis. During the early twentieth century, developments in the fields of genetics, statistics, and epidemiology provided concepts and methods that permitted investigators to recognize important deficiencies in past studies, and to design others in which the critical comparisons could be made between patient groups and control groups. Registries of cancer incidence in large populations became available in several countries in the middle twentieth century, providing a standard "control group" for comparison. Large surveys of site-specific cancer experience in families, rigorously designed and analyzed, found for most kinds of cancers a two- to threefold increased risk for close relatives of propositi. These studies also reemphasized the great difficulty in obtaining even minimally complete family health history information, and the importance of verifying all reported cases with medical or vital records. Although clinical and laboratory investigation will be necessary to understand the mechanisms by which human genes may predispose to cancer, epidemiological approaches can estimate the extent to which genetic etiological factors may be present in a population, whether a general population or one defined by other factors under investigation. Population-based studies are already of practical significance to the clinical geneticist in the estimation of risk of eventual cancer development in unaffected family members, and can be expected to continue to identify specific groups and characteristics associated with genetic cancer

  3. Bacterial Population Genetics in a Forensic Context

    Energy Technology Data Exchange (ETDEWEB)

    Velsko, S P

    2009-11-02

    This report addresses the recent Department of Homeland Security (DHS) call for a Phase I study to (1) assess gaps in the forensically relevant knowledge about the population genetics of eight bacterial agents of concern, (2) formulate a technical roadmap to address those gaps, and (3) identify new bioinformatics tools that would be necessary to analyze and interpret population genetic data in a forensic context. The eight organisms that were studied are B. anthracis, Y. pestis, F. tularensis, Brucella spp., E. coli O157/H7, Burkholderia mallei, Burkholderia pseudomallei, and C. botulinum. Our study focused on the use of bacterial population genetics by forensic investigators to test hypotheses about the possible provenance of an agent that was used in a crime or act of terrorism. Just as human population genetics underpins the calculations of match probabilities for human DNA evidence, bacterial population genetics determines the level of support that microbial DNA evidence provides for or against certain well-defined hypotheses about the origins of an infecting strain. Our key findings are: (1) Bacterial population genetics is critical for answering certain types of questions in a probabilistic manner, akin (but not identical) to 'match probabilities' in DNA forensics. (2) A basic theoretical framework for calculating likelihood ratios or posterior probabilities for forensic hypotheses based on microbial genetic comparisons has been formulated. This 'inference-on-networks' framework has deep but simple connections to the population genetics of mtDNA and Y-STRs in human DNA forensics. (3) The 'phylogeographic' approach to identifying microbial sources is not an adequate basis for understanding bacterial population genetics in a forensic context, and has limited utility, even for generating 'leads' with respect to strain origin. (4) A collection of genotyped isolates obtained opportunistically from international locations

  4. Profesionales y Profesores del Urbanismo. Siglo XX en la F.A.U. de la Universidad de Chile. /Urban Professionals and Professors. Twentieth century in the F.A.U. University of Chile

    Directory of Open Access Journals (Sweden)

    Pavez Reyes, María Isabel

    2000-08-01

    Full Text Available En el marco de las celebraciones de los 150 años de la Enseñanza de la Arquitectura en la Universidad de Chile y, de los 50 años del Departamento de Urbanismo de la Facultad de Arquitectura y Urbanismo se rinde homenaje a los profesionales y profesores del Urbanismo en nuestra casa de estudios en siglo XX./ As part of the celebrations of 150 years of the Teaching of Architecture at the University of Chile and, when the Department of Urban Planning School of Architecture and Urban Design is celebrating 50 years since its creation (experimental 1949 / 1952 official - 1999/2002, we recall the urban planning professionals and professors in our university in the twentieth century.

  5. Genetic Heterogeneity in Algerian Human Populations.

    Science.gov (United States)

    Bekada, Asmahan; Arauna, Lara R; Deba, Tahria; Calafell, Francesc; Benhamamouch, Soraya; Comas, David

    2015-01-01

    The demographic history of human populations in North Africa has been characterized by complex processes of admixture and isolation that have modeled its current gene pool. Diverse genetic ancestral components with different origins (autochthonous, European, Middle Eastern, and sub-Saharan) and genetic heterogeneity in the region have been described. In this complex genetic landscape, Algeria, the largest country in Africa, has been poorly covered, with most of the studies using a single Algerian sample. In order to evaluate the genetic heterogeneity of Algeria, Y-chromosome, mtDNA and autosomal genome-wide makers have been analyzed in several Berber- and Arab-speaking groups. Our results show that the genetic heterogeneity found in Algeria is not correlated with geography or linguistics, challenging the idea of Berber groups being genetically isolated and Arab groups open to gene flow. In addition, we have found that external sources of gene flow into North Africa have been carried more often by females than males, while the North African autochthonous component is more frequent in paternally transmitted genome regions. Our results highlight the different demographic history revealed by different markers and urge to be cautious when deriving general conclusions from partial genomic information or from single samples as representatives of the total population of a region.

  6. Great ape genetic diversity and population history

    DEFF Research Database (Denmark)

    Prado-Martinez, Javier; Sudmant, Peter H.; Kidd, Jeffrey M.

    2013-01-01

    Most great ape genetic variation remains uncharacterized; however, its study is critical for understanding population history, recombination, selection and susceptibility to disease. Here we sequence to high coverage a total of 79 wild- and captive-born individuals representing all six great ape...

  7. Sardinian Population (Italy): a Genetic Review

    African Journals Online (AJOL)

    thou

    The demographic history of Sardinia is that of a population which over the centuries has battled ... period to the present day, a positive trend of demographic development has characterized the ... and to have maintained a genetic identity through their evolution: the cluster constituted .... Haplotype H varies from 41.2% at.

  8. Genetic sources of population epigenomic variation

    NARCIS (Netherlands)

    Taudt, Aaron; Colome-Tatche, Maria; Johannes, Frank

    The field of epigenomics has rapidly progressed from the study of individual reference epigenomes to surveying epigenomic variation in populations. Recent studies in a number of species, from yeast to humans, have begun to dissect the cis- and trans-regulatory genetic mechanisms that shape patterns

  9. Dwudziestowieczna filozofia analityczna. O pewnej próbie całościowego ujęcia (TWENTIETH-CENTURY ANALYTIC PHILOSOPHY. ON A RECENT ATTEMPT OF ITS GENERAL ACCOUNT

    Directory of Open Access Journals (Sweden)

    Tadeusz Szubka

    2007-06-01

    Full Text Available Although analytic philosophy is a major movement shaping contemporary philosophy, there are not too many historical accounts of that movement which would be comprehensive, unified and sufficiently detailed. An impressive attempt to fill in this lacuna is the two-volume book 'Philosophical Analysis in the Twentieth Century', modestly described by its author Scott Soames (renowned mainly for his work in the philosophy of language as 'an introductory overview of the analytic tradition in philosophy covering roughly the period between 1900 and 1975'. The first volume discusses the philosophy of G.E. Moore, the most influential views of Bertrand Russell, Ludwig Wittgenstein's 'Tractatus', logical positivism (including emotivism in ethics and reaction against it, as well as the early philosophy of W.V. Quine. The second volume continues the story of analytic philosophy by providing an account of the later philosophy of Wittgenstein, the ordinary language philosophy and its demise, the philosophical naturalism of W.V. Quine, the theory of meaning of Donald Davidson, and finally Saul Kripke's seminal philosophy of language and its wide-ranging implications. The book contains also a short epilogue outlining the direction taken by analytic philosophy in the last quarter of the twentieth century. The two volumes of Soames' account of contemporary analytic tradition are packed with lucid, sophisticated and detailed discussions of various views of major thinkers of that tradition. However, besides these merits the book by Soames has several weaker points. It defines analytic philosophy in a rather loose and unspecific manner, as well as gives an arbitrarily selective and unbalanced account of its recent developments.

  10. Anticolonial climates: physiology, ecology, and global population, 1920s-1950s.

    Science.gov (United States)

    Bashford, Alison

    2012-01-01

    Historiography on tropical medicine and determinist ideas about climate and racial difference rightly focuses on links with nineteenth- and twentieth-century colonial rule. Occasionally and counterintuitively, however, these ideas have been redeployed as anticolonial argument. This article looks at one such instance; the racial physiology of Indian economist, ecologist, and anticolonial nationalist Radhakamal Mukerjee (1889-1968). It argues that the explanatory context was mid-twentieth-century discussion of global population growth, which raised questions of density and belonging to land. Ecology offered a new language and scientific system within which people and place were conceptually integrated, in this instance to anticolonial ends.

  11. Accomplishments and new challenges in dairy genetic evaluations

    Directory of Open Access Journals (Sweden)

    Christian Maltecca

    Full Text Available This review presents the evolution of dairy genetic methods to estimate breeding values. For centuries, human action has shaped animal populations by choosing progenitors of the next generation. Since the twentieth century, applied concepts were integrated into a new discipline, quantitative genetics. The past quarter-century in genetic evaluation of dairy cattle has been marked by evolution in methodology and computer capacity, expansion in the array of evaluated traits, and globalization. Selection index was replaced by mixed model procedures and animal models replaced by sire and sire-maternal grandsire models. Recently, application of Bayesian theory to breeding values prediction and variance components estimation has become standard. Individual test-day observations have been used more effectively in the estimation of lactation yield as direct input to evaluation models. Computer speed and storage are less limiting in choosing procedures. National evaluations combined internationally provide evaluations for bulls from all participating countries on each of the national scales, facilitating choices from among many more bulls. Selection within countries has increased inbreeding and the use of similar genetics across countries reduces the previously available genetic diversity. Finally, considerable progress in genomics has created a new tool, genomic selection. The collection and analysis of several types of phenotypic data to evaluate genetic merit will continue to be the most important tool for genetic progress in the foreseeable future. Information will increasingly be obtained from smaller reference populations and the extrapolation from these data will require careful validation.

  12. Alignment-free phylogenetics and population genetics.

    Science.gov (United States)

    Haubold, Bernhard

    2014-05-01

    Phylogenetics and population genetics are central disciplines in evolutionary biology. Both are based on comparative data, today usually DNA sequences. These have become so plentiful that alignment-free sequence comparison is of growing importance in the race between scientists and sequencing machines. In phylogenetics, efficient distance computation is the major contribution of alignment-free methods. A distance measure should reflect the number of substitutions per site, which underlies classical alignment-based phylogeny reconstruction. Alignment-free distance measures are either based on word counts or on match lengths, and I apply examples of both approaches to simulated and real data to assess their accuracy and efficiency. While phylogeny reconstruction is based on the number of substitutions, in population genetics, the distribution of mutations along a sequence is also considered. This distribution can be explored by match lengths, thus opening the prospect of alignment-free population genomics.

  13. Loss of genetic diversity in Maculinea populations over 10 years

    DEFF Research Database (Denmark)

    Nash, David Richard; Lomborg, Andreas Eg

    I will present the results of research on the population genetics of Maculinea alcon and M. arion in Southern scandinavia, which shows a strong decrease in genetic diversity in most populations, even if those populations are apparently otherwise healthy.......I will present the results of research on the population genetics of Maculinea alcon and M. arion in Southern scandinavia, which shows a strong decrease in genetic diversity in most populations, even if those populations are apparently otherwise healthy....

  14. Genetic classification of populations using supervised learning.

    LENUS (Irish Health Repository)

    Bridges, Michael

    2011-01-01

    There are many instances in genetics in which we wish to determine whether two candidate populations are distinguishable on the basis of their genetic structure. Examples include populations which are geographically separated, case-control studies and quality control (when participants in a study have been genotyped at different laboratories). This latter application is of particular importance in the era of large scale genome wide association studies, when collections of individuals genotyped at different locations are being merged to provide increased power. The traditional method for detecting structure within a population is some form of exploratory technique such as principal components analysis. Such methods, which do not utilise our prior knowledge of the membership of the candidate populations. are termed unsupervised. Supervised methods, on the other hand are able to utilise this prior knowledge when it is available.In this paper we demonstrate that in such cases modern supervised approaches are a more appropriate tool for detecting genetic differences between populations. We apply two such methods, (neural networks and support vector machines) to the classification of three populations (two from Scotland and one from Bulgaria). The sensitivity exhibited by both these methods is considerably higher than that attained by principal components analysis and in fact comfortably exceeds a recently conjectured theoretical limit on the sensitivity of unsupervised methods. In particular, our methods can distinguish between the two Scottish populations, where principal components analysis cannot. We suggest, on the basis of our results that a supervised learning approach should be the method of choice when classifying individuals into pre-defined populations, particularly in quality control for large scale genome wide association studies.

  15. Genetic structure of nine horse populations

    Directory of Open Access Journals (Sweden)

    Monika Burócziová

    2008-01-01

    Full Text Available In the present study was estimate the genetic diversity and relationships among nine horses breeds in Czech and Slovak Republic.In conclusion, the main objective of study was to show the level of genetic distance among the horse breeds with different history of breeding of each country. Furthermore, it should be clarified whether these populations and subpopulations are distinct enough from each other to justify defining separate breeds. This research concerns the variability of microsatellite markers in genotypes of horse. We compared the genetic diversity and distance among nine horse breeds Czech and Slovak Warmblood both of Czech origin, Slovak Warmblood of Slovak origin, Hucul, Hafling, Furioso, Noriker, Silesian Noriker and Bohemian-Moravian Belgian Horse.In total, 932 animals were genotyped for 17 microsatellites markers (AHT4, AHT5, ASB2, HMS3, HMS6, HMS7, HTG4, HTG10, VHL20, HTG6, HMS2, HTG7, ASB17, ASB23, CA425, HMS1, LEX3 recommended by the International Society of Animal Genetics.In the different population size, the allele frequencies, observed and expected heterozygosity, test for deviations from Hardy-Weinberg equilibrium and Polymorphism information content have been calculated for each breed. We analyzed genetic distance and diversity among them on the base of the dataset of highly polymorphic set of microsatellites representing all autozomes using set of PowerMar­ker v3.25 analysis tools and Structure 2.2. programme for results comparison.

  16. A population genetics model of linkage disequilibrium in admixed populations

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Understanding linkage disequilibrium (LD) created in admixed population and the rate of decay in the disequilibrium over evolution is an important subject in population genetics theory and in disease gene mapping in human populations. The present study represents the theoretical investigation of effects of gene frequencies, levels of LD and admixture proportions of donor populations on the evolutionary dynamics of the LD of the admixed population. We examined the conditions under which the admixed population reached linkage equilibrium or the peak level of the LD. The study reveals the inappropriateness in approximating the dynamics of the LD generated by population admixture by the commonly used formula in literature. An appropriate equation for the dynamics is proposed. The distinct feature of the newly suggested formula is that the value of the nonlinear component of the LD remains constant in the first generation of the population evolution. Comparison between the predicted disequilibrium dynamics shows that the error will be caused by using the old formula, and thus resulting in a misguidance in using the evolutionary information of the admixed population in gene mapping.

  17. Deep Learning for Population Genetic Inference.

    Directory of Open Access Journals (Sweden)

    Sara Sheehan

    2016-03-01

    Full Text Available Given genomic variation data from multiple individuals, computing the likelihood of complex population genetic models is often infeasible. To circumvent this problem, we introduce a novel likelihood-free inference framework by applying deep learning, a powerful modern technique in machine learning. Deep learning makes use of multilayer neural networks to learn a feature-based function from the input (e.g., hundreds of correlated summary statistics of data to the output (e.g., population genetic parameters of interest. We demonstrate that deep learning can be effectively employed for population genetic inference and learning informative features of data. As a concrete application, we focus on the challenging problem of jointly inferring natural selection and demography (in the form of a population size change history. Our method is able to separate the global nature of demography from the local nature of selection, without sequential steps for these two factors. Studying demography and selection jointly is motivated by Drosophila, where pervasive selection confounds demographic analysis. We apply our method to 197 African Drosophila melanogaster genomes from Zambia to infer both their overall demography, and regions of their genome under selection. We find many regions of the genome that have experienced hard sweeps, and fewer under selection on standing variation (soft sweep or balancing selection. Interestingly, we find that soft sweeps and balancing selection occur more frequently closer to the centromere of each chromosome. In addition, our demographic inference suggests that previously estimated bottlenecks for African Drosophila melanogaster are too extreme.

  18. Deep Learning for Population Genetic Inference.

    Science.gov (United States)

    Sheehan, Sara; Song, Yun S

    2016-03-01

    Given genomic variation data from multiple individuals, computing the likelihood of complex population genetic models is often infeasible. To circumvent this problem, we introduce a novel likelihood-free inference framework by applying deep learning, a powerful modern technique in machine learning. Deep learning makes use of multilayer neural networks to learn a feature-based function from the input (e.g., hundreds of correlated summary statistics of data) to the output (e.g., population genetic parameters of interest). We demonstrate that deep learning can be effectively employed for population genetic inference and learning informative features of data. As a concrete application, we focus on the challenging problem of jointly inferring natural selection and demography (in the form of a population size change history). Our method is able to separate the global nature of demography from the local nature of selection, without sequential steps for these two factors. Studying demography and selection jointly is motivated by Drosophila, where pervasive selection confounds demographic analysis. We apply our method to 197 African Drosophila melanogaster genomes from Zambia to infer both their overall demography, and regions of their genome under selection. We find many regions of the genome that have experienced hard sweeps, and fewer under selection on standing variation (soft sweep) or balancing selection. Interestingly, we find that soft sweeps and balancing selection occur more frequently closer to the centromere of each chromosome. In addition, our demographic inference suggests that previously estimated bottlenecks for African Drosophila melanogaster are too extreme.

  19. Deep Learning for Population Genetic Inference

    Science.gov (United States)

    Sheehan, Sara; Song, Yun S.

    2016-01-01

    Given genomic variation data from multiple individuals, computing the likelihood of complex population genetic models is often infeasible. To circumvent this problem, we introduce a novel likelihood-free inference framework by applying deep learning, a powerful modern technique in machine learning. Deep learning makes use of multilayer neural networks to learn a feature-based function from the input (e.g., hundreds of correlated summary statistics of data) to the output (e.g., population genetic parameters of interest). We demonstrate that deep learning can be effectively employed for population genetic inference and learning informative features of data. As a concrete application, we focus on the challenging problem of jointly inferring natural selection and demography (in the form of a population size change history). Our method is able to separate the global nature of demography from the local nature of selection, without sequential steps for these two factors. Studying demography and selection jointly is motivated by Drosophila, where pervasive selection confounds demographic analysis. We apply our method to 197 African Drosophila melanogaster genomes from Zambia to infer both their overall demography, and regions of their genome under selection. We find many regions of the genome that have experienced hard sweeps, and fewer under selection on standing variation (soft sweep) or balancing selection. Interestingly, we find that soft sweeps and balancing selection occur more frequently closer to the centromere of each chromosome. In addition, our demographic inference suggests that previously estimated bottlenecks for African Drosophila melanogaster are too extreme. PMID:27018908

  20. J. B. S. Haldane, Ernst Mayr and the Beanbag genetics dispute.

    Science.gov (United States)

    Rao, Veena; Nanjundiah, Vidyanand

    2011-01-01

    Starting from the early decades of the twentieth century, evolutionary biology began to acquire mathematical overtones. This took place via the development of a set of models in which the Darwinian picture of evolution was shown to be consistent with the laws of heredity discovered by Mendel. The models, which came to be elaborated over the years, define a field of study known as population genetics. Population genetics is generally looked upon as an essential component of modern evolutionary theory. This article deals with a famous dispute between J. B. S. Haldane, one of the founders of population genetics, and Ernst Mayr, a major contributor to the way we understand evolution. The philosophical undercurrents of the dispute remain relevant today. Mayr and Haldane agreed that genetics provided a broad explanatory framework for explaining how evolution took place but differed over the relevance of the mathematical models that sought to underpin that framework. The dispute began with a fundamental issue raised by Mayr in 1959: in terms of understanding evolution, did population genetics contribute anything beyond the obvious? Haldane's response came just before his death in 1964. It contained a spirited defense, not just of population genetics, but also of the motivations that lie behind mathematical modelling in biology. While the difference of opinion persisted and was not glossed over, the two continued to maintain cordial personal relations.

  1. Population Genetics of Three Dimensional Range Expansions

    Science.gov (United States)

    Lavrentovich, Maxim; Nelson, David

    2014-03-01

    We develop a simple model of genetic diversity in growing spherical cell clusters, where the growth is confined to the cluster surface. This kind of growth occurs in cells growing in soft agar, and can also serve as a simple model of avascular tumors. Mutation-selection balance in these radial expansions is strongly influenced by scaling near a neutral, voter model critical point and by the inflating frontier. We develop a scaling theory to describe how the dynamics of mutation-selection balance is cut off by inflation. Genetic drift, i.e., local fluctuations in the genetic diversity, also plays an important role, and can lead to the extinction even of selectively advantageous strains. We calculate this extinction probability, taking into account the effect of rough population frontiers.

  2. Temporal Genetic Variance and Propagule-Driven Genetic Structure Characterize Naturalized Rainbow Trout (Oncorhynchus mykiss) from a Patagonian Lake Impacted by Trout Farming

    Science.gov (United States)

    Seeb, Lisa W.; Seeb, James E.; Arismendi, Ivan; Hernández, Cristián E.; Gajardo, Gonzalo; Galleguillos, Ricardo; Cádiz, Maria I.; Musleh, Selim S.

    2015-01-01

    Knowledge about the genetic underpinnings of invasions—a theme addressed by invasion genetics as a discipline—is still scarce amid well documented ecological impacts of non-native species on ecosystems of Patagonia in South America. One of the most invasive species in Patagonia’s freshwater systems and elsewhere is rainbow trout (Oncorhynchus mykiss). This species was introduced to Chile during the early twentieth century for stocking and promoting recreational fishing; during the late twentieth century was reintroduced for farming purposes and is now naturalized. We used population- and individual-based inference from single nucleotide polymorphisms (SNPs) to illuminate three objectives related to the establishment and naturalization of Rainbow Trout in Lake Llanquihue. This lake has been intensively used for trout farming during the last three decades. Our results emanate from samples collected from five inlet streams over two seasons, winter and spring. First, we found that significant intra- population (temporal) genetic variance was greater than inter-population (spatial) genetic variance, downplaying the importance of spatial divergence during the process of naturalization. Allele frequency differences between cohorts, consistent with variation in fish length between spring and winter collections, might explain temporal genetic differences. Second, individual-based Bayesian clustering suggested that genetic structure within Lake Llanquihue was largely driven by putative farm propagules found at one single stream during spring, but not in winter. This suggests that farm broodstock might migrate upstream to breed during spring at that particular stream. It is unclear whether interbreeding has occurred between “pure” naturalized and farm trout in this and other streams. Third, estimates of the annual number of breeders (Nb) were below 73 in half of the collections, suggestive of genetically small and recently founded populations that might experience

  3. Survival, reproduction, and immigration explain the dynamics of a local Red-backed Shrike population in the Netherlands

    NARCIS (Netherlands)

    Hemerik, L.; Geertsma, M.; Waasdorp, S.; Middelveld, R.P.; Kleef, van H.; Klok, T.C.

    2015-01-01

    Populations of many bird species strongly declined in Western Europe in the late twentieth century. One such species is the Red-backed Shrike in the Netherlands. In one of the last strongholds of this species, the Bargerveen Reserve, the breeding population flourished in the 1990s due to rewetting m

  4. Bacterial Population Genetics in a Forensic Context

    Energy Technology Data Exchange (ETDEWEB)

    Velsko, S P

    2009-11-02

    This report addresses the recent Department of Homeland Security (DHS) call for a Phase I study to (1) assess gaps in the forensically relevant knowledge about the population genetics of eight bacterial agents of concern, (2) formulate a technical roadmap to address those gaps, and (3) identify new bioinformatics tools that would be necessary to analyze and interpret population genetic data in a forensic context. The eight organisms that were studied are B. anthracis, Y. pestis, F. tularensis, Brucella spp., E. coli O157/H7, Burkholderia mallei, Burkholderia pseudomallei, and C. botulinum. Our study focused on the use of bacterial population genetics by forensic investigators to test hypotheses about the possible provenance of an agent that was used in a crime or act of terrorism. Just as human population genetics underpins the calculations of match probabilities for human DNA evidence, bacterial population genetics determines the level of support that microbial DNA evidence provides for or against certain well-defined hypotheses about the origins of an infecting strain. Our key findings are: (1) Bacterial population genetics is critical for answering certain types of questions in a probabilistic manner, akin (but not identical) to 'match probabilities' in DNA forensics. (2) A basic theoretical framework for calculating likelihood ratios or posterior probabilities for forensic hypotheses based on microbial genetic comparisons has been formulated. This 'inference-on-networks' framework has deep but simple connections to the population genetics of mtDNA and Y-STRs in human DNA forensics. (3) The 'phylogeographic' approach to identifying microbial sources is not an adequate basis for understanding bacterial population genetics in a forensic context, and has limited utility, even for generating 'leads' with respect to strain origin. (4) A collection of genotyped isolates obtained opportunistically from international locations

  5. Reliability of genetic bottleneck tests for detecting recent population declines

    NARCIS (Netherlands)

    Peery, M. Zachariah; Kirby, Rebecca; Reid, Brendan N.; Stoelting, Ricka; Doucet-Beer, Elena; Robinson, Stacie; Vasquez-Carrillo, Catalina; Pauli, Jonathan N.; Palsboll, Per J.

    2012-01-01

    The identification of population bottlenecks is critical in conservation because populations that have experienced significant reductions in abundance are subject to a variety of genetic and demographic processes that can hasten extinction. Genetic bottleneck tests constitute an appealing and popula

  6. Genetic diversity in introduced populations with an Allee effect.

    Science.gov (United States)

    Wittmann, Meike J; Gabriel, Wilfried; Metzler, Dirk

    2014-09-01

    A phenomenon that strongly influences the demography of small introduced populations and thereby potentially their genetic diversity is the demographic Allee effect, a reduction in population growth rates at small population sizes. We take a stochastic modeling approach to investigate levels of genetic diversity in populations that successfully overcame either a strong Allee effect, in which populations smaller than a certain critical size are expected to decline, or a weak Allee effect, in which the population growth rate is reduced at small sizes but not negative. Our results indicate that compared to successful populations without an Allee effect, successful populations with a strong Allee effect tend to (1) derive from larger founder population sizes and thus have a higher initial amount of genetic variation, (2) spend fewer generations at small population sizes where genetic drift is particularly strong, and (3) spend more time around the critical population size and thus experience more genetic drift there. In the case of multiple introduction events, there is an additional increase in diversity because Allee-effect populations tend to derive from a larger number of introduction events than other populations. Altogether, a strong Allee effect can either increase or decrease genetic diversity, depending on the average founder population size. By contrast, a weak Allee effect tends to decrease genetic diversity across the entire range of founder population sizes. Finally, we show that it is possible in principle to infer critical population sizes from genetic data, although this would require information from many independently introduced populations.

  7. A population genetics view of animal domestication.

    Science.gov (United States)

    Larson, Greger; Burger, Joachim

    2013-04-01

    The fundamental shift associated with the domestication of plants and animals allowed for a dramatic increase in human population sizes and the emergence of modern society. Despite its importance and the decades of research devoted to studying it, questions regarding the origins and processes of domestication remain. Here, we review recent theoretical advances and present a perspective that underscores the crucial role that population admixture has played in influencing the genomes of domestic animals over the past 10000 years. We then discuss novel approaches to generating and analysing genetic data, emphasising the importance of an explicit hypothesis-testing approach for the inference of the origins and subsequent evolution and demography of domestic animals. By applying next-generation sequencing technology alongside appropriate biostatistical methodologies, a substantially deeper understanding of domestication is on the horizon.

  8. A return to the ‘pretty house’. An interpretative bricolage of documentary sources on menarche rituals among the native peoples of the Argentine Patagonia (nineteenth and twentieth centuries

    Directory of Open Access Journals (Sweden)

    Graciela Hernández

    2015-12-01

    Full Text Available The main aim of this work is to put into consideration a new analysis of the text by the British author George Musters, of his description of a menarche ceremony (which he called “the pretty house” that was observed among the Tehuelches from the Patagonia in 1869, in order to contextualize it from the historic point of view and from a gender perspective.From qualitative methodology we have made a bricolage which expresses an itinerary articulated by a genealogy of documentary sources from the nineteenth century, by testimonies produced in anthropological and linguistic works in the second half of the twentieth century, and by ethnographic records of our works in oral history which focus on rituals to foster the yarns.The comparison of sources of the selected documents leads us to think about the hypothesis that in the ceremonies of the first menstruation, from the nineteenth century on, it was fostered the attachment to yarns and fabric, in societies which also ritualized the field of textile work.

  9. Transition from traditional to modern forest management shaped the spatial extent of cattle pasturing in Białowieża Primeval Forest in the nineteenth and twentieth centuries.

    Science.gov (United States)

    Samojlik, Tomasz; Fedotova, Anastasia; Kuijper, Dries P J

    2016-12-01

    Pasturing of livestock in forests has had profound consequences for Europe's landscapes. In Białowieża Primeval Forest (BPF), cattle pasturing was a part of traditional forest use that ceased only in the second half of the twentieth century. We collected information on the institutional changes governing forest cattle pasturing and the changes in spatial extent of cattle presence in BPF in last two centuries and information on cattle numbers and their impact on forest regeneration. The spatial extent of cattle pasturing was highly variable, with the distribution of grazing areas frequently changing. Forest near villages (constituting less than 10 % of the area) was most often used for cattle grazing during continued longer time periods. Historical data showed that cattle have had a clear impact on forest regeneration. However, the frequent changes that occurred in the extent of cattle grazing indicate that their impact occurred locally, was smaller in other less intensively used areas, and in the forest as a whole.

  10. The Expressions of Mao Zedong's Poems to the Chinese Cultural Transition in the Twentieth Century%毛泽东诗词对20世纪中国文化转型的表达

    Institute of Scientific and Technical Information of China (English)

    华玉振

    2016-01-01

    The twentieth century was the period when the Chinese culture was difficult to choose its fu-ture directions confronted with the disputes between China and the West,the ancient and the modern.Then it started to transit from the traditions to modernization.As the representative of Chinese cultural transi-tion in the 20th century,Mao Zedong's poems artfully spread the historical pictures from criticizing and in-heriting the Chinese traditional culture to constructing the modern culture.They also revealed some contra-dictions,errors and paranoia caused by the historical and personal factors.%20世纪是中国文化面临中西之争、古今之辩最为激烈,民族文化前景抉择最为艰难的时期,开始了中国文化从传统向现代的转型。毛泽东是20世纪中国文化转型的代表。在这个转型过程中,毛泽东诗词艺术地铺展了从批判传统文化、继承传统文化再到建构中国现代文化的历史性画卷,以及基于历史与个人因素而导致的矛盾、错误及偏执。

  11. The historical memory of the twentieth Century silent film era of the Hollywood of a movie%一部电影与对20世纪好莱坞默片时代的历史记忆

    Institute of Scientific and Technical Information of China (English)

    王欢欢

    2013-01-01

    历史记忆是心理学的研究问题,最近几年成为多们学科关注的话题。历史记忆离不开社会、集体,是在现有的社会文化背景下对过去的构建。进入21世纪,影视传媒一如既往地发挥着强大的社会功能,影视传媒是形塑历史的最主要途径之一,本文以《艺术家》对20世纪好莱坞默片时代的历史记忆为例,探讨电影构建的历史记忆与历史真实之间的差异。%Historical memory is to study the problem of psychology, in recent years become a multi discipline topic. Historical memory cannot do without the society and group, is available in the social and cultural background of past construction. In twenty-first Century, film and television media to play strong social function, television media is one of the most important ways to shape plastic history, based on the historical memories of the"artist"of twentieth Century silent film era of the Hollywood as an example, to discuss the difference between the historical memory and historical truth of the movie.

  12. Myth,Revolt and Modernity:Syria's Poetry Creation in the Twentieth Century%论20世纪叙利亚诗歌流变与代表诗人

    Institute of Scientific and Technical Information of China (English)

    邱婧

    2016-01-01

    As one of the important achievements in the moderating transition of Arabic literature , Syria's poetry creation in the twentieth century was plentiful .Most of Syria's poets had western living experi-ence;moreover , they had blended the tradition of Islamic religion with the style of the modern poetry .The myth and revolt due to the politics and nationalism were also infused into the poem .Thereby ,.This novel poetry phenomenon was worth of studying in the world literature .%20世纪的叙利亚诗歌作品十分丰富,是阿拉伯文学现代性转换时期的重要成果之一。20世纪的叙利亚诗人们大多具有西方生活的经验背景,在其诗歌创作中糅合了伊斯兰的宗教传统以及现代新诗的样式,又因政治风云和民族主义的形成而激发了其作品中的迷思和反抗。由此,20世纪的叙利亚诗歌完成了从代言、隐喻到现代性的诗歌流变,是世界文学中较为独特的诗歌现象之一。

  13. Los diarios como espacios públicos: La Prensa en la vida social de Buenos Aires a comienzos del siglo XX Newspapers As Public Spaces: La Prensa In The Social Life Of Buenos Aires In The Early Twentieth Century

    Directory of Open Access Journals (Sweden)

    Hernán E. Gómez

    2008-12-01

    Full Text Available En las primeras décadas del siglo XX, en Argentina, los grandes diarios fueron un fenómeno periodístico y social. Instalados en el centro de la ciudad muchos de ellos abrieron sus puertas al público convirtiéndose en lugares de reuniones, conferencias, manifestaciones, etc. Un caso ejemplar fue el del diario La Prensa cuyo análisis permite discutir críticamente la consideración de los diarios simplemente como productores del soporte impreso de la esfera pública (uno de los fundamentos del modelo elaborado por Jürgen Habermas y analizarlos no sólo como locus de un conjunto de relaciones humanas especializadas (las que hacen a la producción de los diarios sino también como espacios públicos.At the turn of the twentieth century in Argentina the grandes diarios were a journalistic and social phenomenon. Localized in the core of the city, many of them opened their doors to the public, thus becoming a place for meetings, parties, and conferences. An exemplary case was La Prensa; the study of which enables both a critical discussion of representations of newspapers as the print supporter of the public sphere (one of the bases of Jürgen Habermas' model and their analysis not only as the locus of a group of specialised human relations (those involved in newspaper production but also as public places.

  14. Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.

    NARCIS (Netherlands)

    K. Sleegers (Kristel); F. Forey; J. Theuns (Jessie); Y.S. Aulchenko (Yurii); S. Rademakers (Suzanne); M. Cruts (Marc); W.A. van Gool (Willem); P. Heutink (Peter); B.A. Oostra (Ben); J.C. van Swieten (John); C.M. van Duijn (Cock); C. van Broeckhoven (Christine)

    2004-01-01

    textabstractDespite advances in elucidating the genetic epidemiology of Alzheimer's disease and frontotemporal dementia, the aetiology for most patients with dementia remains unclear. We examined the genetic epidemiology of dementia in a recent genetically isolated Dutch population founded around

  15. The population genetics of cooperative gene regulation

    Directory of Open Access Journals (Sweden)

    Stewart Alexander J

    2012-09-01

    Full Text Available Abstract Background Changes in gene regulatory networks drive the evolution of phenotypic diversity both within and between species. Rewiring of transcriptional networks is achieved either by changes to transcription factor binding sites or by changes to the physical interactions among transcription factor proteins. It has been suggested that the evolution of cooperative binding among factors can facilitate the adaptive rewiring of a regulatory network. Results We use a population-genetic model to explore when cooperative binding of transcription factors is favored by evolution, and what effects cooperativity then has on the adaptive re-writing of regulatory networks. We consider a pair of transcription factors that regulate multiple targets and overlap in the sets of target genes they regulate. We show that, under stabilising selection, cooperative binding between the transcription factors is favoured provided the amount of overlap between their target genes exceeds a threshold. The value of this threshold depends on several population-genetic factors: strength of selection on binding sites, cost of pleiotropy associated with protein-protein interactions, rates of mutation and population size. Once it is established, we find that cooperative binding of transcription factors significantly accelerates the adaptive rewiring of transcriptional networks under positive selection. We compare our qualitative predictions to systematic data on Saccharomyces cerevisiae transcription factors, their binding sites, and their protein-protein interactions. Conclusions Our study reveals a rich set of evolutionary dynamics driven by a tradeoff between the beneficial effects of cooperative binding at targets shared by a pair of factors, and the detrimental effects of cooperative binding for non-shared targets. We find that cooperative regulation will evolve when transcription factors share a sufficient proportion of their target genes. These findings help to

  16. Genetic Diversity of RAPD Mark for Natural Davidia involucrata Populations

    Institute of Scientific and Technical Information of China (English)

    Congwen Song; Manzhu Bao

    2006-01-01

    The genetic diversity and genetic variation within and among populations of five natural Davidia involucrata populations were studied from 13 primers based on random amplified polymorphic DNA (RAPD) analysis.The results show that natural D.involucrata population has a rich genetic diversity,and the differences among populations are significant.Twenty-six percent of genetic variation exists among D.involucrata populations,which is similar to that of the endangered tree species Liriodendron chinense and Cathaya argyrophylla in China,but different from more widely distributed tree species.The analysis of the impacts of sampling method on genetic diversity parameters shows that the number of sampled individuals has little effect on the effective number of alleles and genetic diversity,but has a marked effect on the genetic differentiation among populations and gene flows.This study divides the provenances of D.involucrata into two parts,namely,a southeast and a northwest provenance.

  17. Genetic drift and the population history of the Irish travellers.

    Science.gov (United States)

    Relethford, John H; Crawford, Michael H

    2013-02-01

    The Irish Travellers are an itinerant group in Ireland that has been socially isolated. Two hypotheses have been proposed concerning the genetic origin of the Travellers: (1) they are genetically related to Roma populations in Europe that share a nomadic lifestyle or (2) they are of Irish origin, and genetic differences from the rest of Ireland reflect genetic drift. These hypotheses were tested using data on 33 alleles from 12 red blood cell polymorphism loci. Comparison with other European, Roma, and Indian populations shows that the Travellers are genetically distinct from the Roma and Indian populations and most genetically similar to Ireland, in agreement with earlier genetic analyses of the Travellers. However, the Travellers are still genetically distinct from other Irish populations, which could reflect some external gene flow and/or the action of genetic drift in a small group that was descended from a small number of founders. In order to test the drift hypothesis, we analyzed genetic distances comparing the Travellers to four geographic regions in Ireland. These distances were then compared with adjusted distances that account for differential genetic drift using a method developed by Relethford (Hum Biol 68 (1996) 29-44). The unadjusted distances show the genetic distinctiveness of the Travellers. After adjustment for the expected effects of genetic drift, the Travellers are equidistant from the other Irish samples, showing their Irish origins and population history. The observed genetic differences are thus a reflection of genetic drift, and there is no evidence of any external gene flow.

  18. Population size and time since island isolation determine genetic diversity loss in insular frog populations.

    Science.gov (United States)

    Wang, Supen; Zhu, Wei; Gao, Xu; Li, Xianping; Yan, Shaofei; Liu, Xuan; Yang, Ji; Gao, Zengxiang; Li, Yiming

    2014-02-01

    Understanding the factors that contribute to loss of genetic diversity in fragmented populations is crucial for conservation measurements. Land-bridge archipelagoes offer ideal model systems for identifying the long-term effects of these factors on genetic variations in wild populations. In this study, we used nine microsatellite markers to quantify genetic diversity and differentiation of 810 pond frogs (Pelophylax nigromaculatus) from 24 islands of the Zhoushan Archipelago and three sites on nearby mainland China and estimated the effects of the island area, population size, time since island isolation, distance to the mainland and distance to the nearest larger island on reduced genetic diversity of insular populations. The mainland populations displayed higher genetic diversity than insular populations. Genetic differentiations and no obvious gene flow were detected among the frog populations on the islands. Hierarchical partitioning analysis showed that only time since island isolation (square-root-transformed) and population size (log-transformed) significantly contributed to insular genetic diversity. These results suggest that decreased genetic diversity and genetic differentiations among insular populations may have been caused by random genetic drift following isolation by rising sea levels during the Holocene. The results provide strong evidence for a relationship between retained genetic diversity and population size and time since island isolation for pond frogs on the islands, consistent with the prediction of the neutral theory for finite populations. Our study highlights the importance of the size and estimated isolation time of populations in understanding the mechanisms of genetic diversity loss and differentiation in fragmented wild populations.

  19. Highlighting nonlinear patterns in population genetics datasets

    KAUST Repository

    Alanis Lobato, Gregorio

    2015-01-30

    Detecting structure in population genetics and case-control studies is important, as it exposes phenomena such as ecoclines, admixture and stratification. Principal Component Analysis (PCA) is a linear dimension-reduction technique commonly used for this purpose, but it struggles to reveal complex, nonlinear data patterns. In this paper we introduce non-centred Minimum Curvilinear Embedding (ncMCE), a nonlinear method to overcome this problem. Our analyses show that ncMCE can separate individuals into ethnic groups in cases in which PCA fails to reveal any clear structure. This increased discrimination power arises from ncMCE\\'s ability to better capture the phylogenetic signal in the samples, whereas PCA better reflects their geographic relation. We also demonstrate how ncMCE can discover interesting patterns, even when the data has been poorly pre-processed. The juxtaposition of PCA and ncMCE visualisations provides a new standard of analysis with utility for discovering and validating significant linear/nonlinear complementary patterns in genetic data.

  20. TRANSGENE ESCAPE MONITORING, POPULATION GENETICS, AND THE LAW

    Science.gov (United States)

    There has been little discussion about how to apply population genetics methods to monitor the spread of transgenes that are detected outside the agricultural populations where they are deployed. Population geneticists have developed tools for analyzing the genetic makeup of indi...

  1. Genetic structure and diversity within and among six populations of ...

    African Journals Online (AJOL)

    Yomi

    2010-04-24

    Apr 24, 2010 ... positive correlation between molecular genetic variation and actual population size. ... Key words: Capparis decidua, Tandhab, Assos, Population size, RAPD markers, Genetic diversity. .... polymorphism in some population, and were monomorphic ... highly informative and produced 152 bands with an ...

  2. CDPOP: A spatially explicit cost distance population genetics program

    Science.gov (United States)

    Erin L. Landguth; S. A. Cushman

    2010-01-01

    Spatially explicit simulation of gene flow in complex landscapes is essential to explain observed population responses and provide a foundation for landscape genetics. To address this need, we wrote a spatially explicit, individual-based population genetics model (CDPOP). The model implements individual-based population modelling with Mendelian inheritance and k-allele...

  3. The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison's disease.

    Science.gov (United States)

    Pedersen, Niels C; Brucker, Lynn; Tessier, Natalie Green; Liu, Hongwei; Penedo, Maria Cecilia T; Hughes, Shayne; Oberbauer, Anita; Sacks, Ben

    2015-01-01

    Sebaceous adenitis (SA) and Addison's disease (AD) increased rapidly in incidence among Standard Poodles after the mid-twentieth century. Previous attempts to identify specific genetic causes using genome wide association studies and interrogation of the dog leukocyte antigen (DLA) region have been non-productive. However, such studies led us to hypothesize that positive selection for desired phenotypic traits that arose in the mid-twentieth century led to intense inbreeding and the inadvertent amplification of AD and SA associated traits. This hypothesis was tested with genetic studies of 761 Standard, Miniature, and Miniature/Standard Poodle crosses from the USA, Canada and Europe, coupled with extensive pedigree analysis of thousands more dogs. Genome-wide diversity across the world-wide population was measured using a panel of 33 short tandem repeat (STR) loci. Allele frequency data were also used to determine the internal relatedness of individual dogs within the population as a whole. Assays based on linkage between STR genomic loci and DLA genes were used to identify class I and II haplotypes and disease associations. Genetic diversity statistics based on genomic STR markers indicated that Standard Poodles from North America and Europe were closely related and reasonably diverse across the breed. However, genetic diversity statistics, internal relatedness, principal coordinate analysis, and DLA haplotype frequencies showed a marked imbalance with 30 % of the diversity in 70 % of the dogs. Standard Poodles with SA and AD were strongly linked to this inbred population, with dogs suffering with SA being the most inbred. No single strong association was found between STR defined DLA class I or II haplotypes and SA or AD in the breed as a whole, although certain haplotypes present in a minority of the population appeared to confer moderate degrees of risk or protection against either or both diseases. Dogs possessing minor DLA class I haplotypes were half as

  4. Transmission function models of finite population genetic algorithms

    NARCIS (Netherlands)

    Kemenade, C.H.M. van; Kok, J.N.; La Poutré, J.A.; Thierens, D.

    1998-01-01

    Infinite population models show a deterministic behaviour. Genetic algorithms with finite populations behave non-deterministicly. For small population sizes, the results obtained with these models differ strongly from the results predicted by the infinite population model. When the population size i

  5. Identifying the genetic components underlying the pathophysiology of movement disorders

    Directory of Open Access Journals (Sweden)

    Ezquerra M

    2011-06-01

    Full Text Available Mario Ezquerra, Yaroslau Compta, Maria J MartiParkinson’s Disease and Movement Disorders Unit, Service of Neurology, Institute of Clinical Neurosciences, Hospital Clinic of Barcelona, IDIBAPS, CIBERNED, SpainAbstract: Movement disorders are a heterogeneous group of neurological conditions, few of which have been classically described as bona fide hereditary illnesses (Huntington’s chorea, for instance. Most are considered to be either sporadic or to feature varying degrees of familial aggregation (parkinsonism and dystonia. In the late twentieth century, Mendelian monogenic mutations were found for movement disorders with a clear and consistent family history. Although important, these findings apply only to very rare forms of movement disorders. Already in the twenty-first century, and taking advantage of the modern developments in genetics and molecular biology, growing attention is being paid to the complex genetics of movement disorders. The search for risk genetic variants (polymorphisms in large cohorts and the identification of different risk variants across different populations and ethnic groups are under way, with the most relevant findings to date corresponding to recent genome wide association studies in Parkinson’s disease. These new approaches focusing on risk variants may enable the design of screening tests for early or even preclinical disease, and the identification of likely therapeutic targets.Keywords: genetics, movement disorders, Parkinson’s disease, parkinsonism, dystonia

  6. 论20世纪中国女性文学创作中的漂泊意识%On the Wandering Consciousness in Twentieth Century Chinese Female Literature

    Institute of Scientific and Technical Information of China (English)

    翟瑞青

    2016-01-01

    The literature works by the twentieth century Chinese women writers is an important part of Chinese new literature unique . Throughout the twentieth century Chinese women literature writing ,there has been a refuge for wandering nothing latent consciousness ,which has its different rendering features though each period .If we placed the women writers’ wandering consciousness in the context of the development of Chinese literature ,we can find its unique significance and value individuality .Women writers have obviously difference between mechanisms and manifestations in terms of awareness generated by wandering from male writers .Since the majority of women writers are more sensitive to their ow n sex characteristics , they have been looking for the existence or construction of their ow n culture from the resistance to the patriarchal culture in the process ,in order to explore female’s culture w hich has long been obscured the significance of individual life .It is female cultural construction process that women writers constantly toward self life to explore the depths of life ,spirit and emotion of the landing site ,in order to place their own long wandering soul and look for the cultural value of their ow n existence .%20世纪中国女性作家的文学创作是中国新文学中独具特色的重要组成部分。在20世纪中国女性文学创作中,一直有一种无所归依的漂泊意识,而且各个时期有着不同的呈现特点。如果把女作家的漂泊意识放置在整个20世纪中国文学发展的大背景中去考察,可以发现其独特的意义与个性价值。在漂泊意识产生的机制和表现形态方面,女作家与男作家显然不同。女作家更加敏感于自身的性别特点,在抗拒男权中心文化的过程中,她们一直在寻找或者建构着自己所存在的文化,发掘女性长期以来被男权文化遮蔽了的个体生命意义。女性文化建构的过程是女性作

  7. Study on nationality of Chinese symphonic music after twentieth Century eighty years%20世纪八十年代后的中国交响音乐的民族性研究

    Institute of Scientific and Technical Information of China (English)

    张星

    2014-01-01

    Chinese symphonic creation enter prosperous period in twentieth Century eighty years, with national characteristics and spirit of the times of the symphonic music, has become the common desire of most musicians. In this paper, China symphonic music since the eighty as the focus, the paper studies on the national level, mainly from the musical form analysis:ethnic melody, five tone scale,"non three"overlap and"the color"connection harmonic language, rich rhythm, Chinese musical tradition structure, rich and enchanting music and color, and tries to extend to the music aesthetics and philosophy culture level.%中国交响音乐的创作在20世纪八十年代以后进入繁荣时期,创作具有中国民族特色和时代精神的交响音乐,已成为大多数音乐家的共同心愿。本文以八十年代以来的中国交响音乐为重点,就其民族性进行研究,主要从音乐形态的层面分析:民族性的旋律、五声性的音阶、“非三度”叠置与“色彩性”连接的和声语言、丰富的节奏节拍、中国音乐的传统结构、丰富迷人的音乐色彩等,并且力图延伸到音乐美学与哲学文化的层面。

  8. Temporal variation in genetic diversity and effective population size of Mediterranean and subalpine Arabidopsis thaliana populations.

    Science.gov (United States)

    Gomaa, Nasr H; Montesinos-Navarro, Alicia; Alonso-Blanco, Carlos; Picó, F Xavier

    2011-09-01

    Currently, there exists a limited knowledge on the extent of temporal variation in population genetic parameters of natural populations. Here, we study the extent of temporal variation in population genetics by genotyping 151 genome-wide SNP markers polymorphic in 466 individuals collected from nine populations of the annual plant Arabidopsis thaliana during 4 years. Populations are located along an altitudinal climatic gradient from Mediterranean to subalpine environments in NE Spain, which has been shown to influence key demographic attributes and life cycle adaptations. Genetically, A. thaliana populations were more variable across space than over time. Common multilocus genotypes were detected several years in the same population, whereas low-frequency multilocus genotypes appeared only 1 year. High-elevation populations were genetically poorer and more variable over time than low-elevation populations, which might be caused by a higher overall demographic instability at higher altitudes. Estimated effective population sizes were low but also showed a significant decreasing trend with increasing altitude, suggesting a deeper impact of genetic drift at high-elevation populations. In comparison with single-year samplings, repeated genotyping over time captured substantially higher amount of genetic variation contained in A. thaliana populations. Furthermore, repeated genotyping of populations provided novel information on the genetic properties of A. thaliana populations and allowed hypothesizing on their underlying mechanisms. Therefore, including temporal genotyping programmes into traditional population genetic studies can significantly increase our understanding of the dynamics of natural populations.

  9. Study on genetic coadaptability of wild quail populations in China

    Institute of Scientific and Technical Information of China (English)

    CHANG; Guobin; CHANG; Hong; LIU; Xiangping; YANG; Zhangping; CHEN; Guohong; ZHAO; Wenming; JI; Dejun; XUE; Yan; HUANG; Feng; HASSAN; Hussein

    2006-01-01

    Genetic coadaptability of wild Japanese quail, wild Common quail and Domestic quail populations in China was studied using 7 microsatellite DNA markers and Monte Carlo method to test genetic disequilibrium. The molecular effects of genetic coadaptability were analyzed through a new statistical model of neutral site. The results showed that genetic coadaptability dominated the genetic disequilibrium of the three quail populations, and totally 16.67%, 9.66% and 10.05% of non-allelic combinations were in the genetic disequilibrium in wild Japanese quail, wild Common quail and Domestic quail populations, respectively. Genetic coadaptability existed at almost all the tested sites. In the molecular point of view, genetic coadaptability plays an important role of keeping lots of polymorphisms in natural populations. Therefore, it is another key factor to the genetic disequilibrium in the population except for linkage. The results enrich the conceptions and connotations of genetic disequilibrium, and help us know more about genetic coadaptability and its effects, and lay a foundation of evaluation and protection of wild quail genetic resources in China.

  10. The Not-so-Dark Ages: ecology for human growth in medieval and early twentieth century Portugal as inferred from skeletal growth profiles.

    Science.gov (United States)

    Cardoso, Hugo F V; Garcia, Susana

    2009-02-01

    This study attempts to address the issue of relative living standards in Portuguese medieval and early 20th century periods. Since the growth of children provides a good measure of environmental quality for the overall population, the skeletal growth profiles of medieval Leiria and early 20th century Lisbon were compared. Results show that growth in femur length of medieval children did not differ significantly from that of early 20th century children, but after puberty medieval adolescents seem to have recovered, as they have significantly longer femora as adults. This is suggestive of greater potential for catch-up growth in medieval adolescents. We suggest that this results from distinct child labor practices, which impact differentially on the growth of Leiria and Lisbon adolescents. Work for medieval children and adolescents were related to family activities, and care and attention were provided by family members. Conversely, in early 20th century Lisbon children were more often sent to factories at around 12 years of age as an extra source of family income, where they were exploited for their labor. Since medieval and early 20th century children were stunted at an early age, greater potential for catch-up growth in medieval adolescents results from exhausting work being added to modern adolescent's burdens of disease and poor diet, when they entered the labor market. Although early 20th century Lisbon did not differ in overall unfavorable living conditions from medieval Leiria, after puberty different child labor practices may have placed modern adolescents at greater risk of undernutrition and poor growth.

  11. Genetic diversity of Ghanaian local chicken populations based on ...

    African Journals Online (AJOL)

    Genetic diversity of Ghanaian local chicken populations based on ... raised across distinct agro-ecological zones and constitute unique populations with variable ... (GHFO) in the southwest and the Coastal Savannah (GHCS) along the coast in ...

  12. Genetic population structure of the Japanese mitten crab Eriocheir ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-03-20

    Mar 20, 2009 ... However, few studies have focused on the population genetic structures of ... There are two main demographic strategies for benthic estuarine macro- .... differentiation existed in the two populations of Okinawa. Pairwise FST ...

  13. Population characteristics of DNA fingerprints in humpback whales (Megaptera novaeangliae).

    Science.gov (United States)

    Baker, C S; Gilbert, D A; Weinrich, M T; Lambertsen, R; Calambokidis, J; McArdle, B; Chambers, G K; O'Brien, S J

    1993-01-01

    Humpback whales exhibit a remarkable social organization that is characterized by seasonal long-distance migration (> 10,000 km/year) between summer feeding grounds in high latitudes and winter calving and breeding grounds in tropical or near-tropical waters. All populations are currently considered endangered as a result of intensive commercial exploitation during the last 200 years. Using three hypervariable minisatellite DNA probes (33.15, 3'HVR, and M13) originally developed for studies of human genetic variation, we examined genetic variation within and among three regional subpopulations of humpback whales from the North Pacific and one from the North Atlantic oceans. Analysis of DNA extracted from skin tissues collected by biopsy darting from free-ranging whales revealed considerable variation in each subpopulation. The extent of this variation argues against a recent history of inbreeding among humpback whales as a result of nineteenth- and twentieth-century hunting. A canonical variate analysis suggested a relationship between scaled genetic distance, based on similarities of DNA fingerprints, and geographic distance (i.e., longitude of regional subpopulation). Significant categorical differences were found between the two oceanic populations using a multivariate analysis of variance (MANOVA) with a modification of the Mantel nonparametric permutation test. The relationship between DNA fingerprint similarities and geographic distance suggests that nuclear gene flow between regional subpopulations within the North Pacific is restricted by relatively low rates of migratory interchange between breeding grounds or assortative mating on common wintering grounds.

  14. Genetic control of mosquitoes: population suppression strategies.

    Science.gov (United States)

    Wilke, André Barretto Bruno; Marrelli, Mauro Toledo

    2012-01-01

    Over the last two decades, morbidity and mortality from malaria and dengue fever among other pathogens are an increasing Public Health problem. The increase in the geographic distribution of vectors is accompanied by the emergence of viruses and diseases in new areas. There are insufficient specific therapeutic drugs available and there are no reliable vaccines for malaria or dengue, although some progress has been achieved, there is still a long way between its development and actual field use. Most mosquito control measures have failed to achieve their goals, mostly because of the mosquito's great reproductive capacity and genomic flexibility. Chemical control is increasingly restricted due to potential human toxicity, mortality in no target organisms, insecticide resistance, and other environmental impacts. Other strategies for mosquito control are desperately needed. The Sterile Insect Technique (SIT) is a species-specific and environmentally benign method for insect population suppression, it is based on mass rearing, radiation mediated sterilization, and release of a large number of male insects. Releasing of Insects carrying a dominant lethal gene (RIDL) offers a solution to many of the drawbacks of traditional SIT that have limited its application in mosquitoes while maintaining its environmentally friendly and species-specific utility. The self-limiting nature of sterile mosquitoes tends to make the issues related to field use of these somewhat less challenging than for self-spreading systems characteristic of population replacement strategies. They also are closer to field use, so might be appropriate to consider first. The prospect of genetic control methods against mosquito vectored human diseases is rapidly becoming a reality, many decisions will need to be made on a national, regional and international level regarding the biosafety, social, cultural and ethical aspects of the use and deployment of these vector control methods.

  15. Genetic Control of Mosquitoes: population suppression strategies

    Directory of Open Access Journals (Sweden)

    André Barretto Bruno Wilke

    2012-10-01

    Full Text Available Over the last two decades, morbidity and mortality from malaria and dengue fever among other pathogens are an increasing Public Health problem. The increase in the geographic distribution of vectors is accompanied by the emergence of viruses and diseases in new areas. There are insufficient specific therapeutic drugs available and there are no reliable vaccines for malaria or dengue, although some progress has been achieved, there is still a long way between its development and actual field use. Most mosquito control measures have failed to achieve their goals, mostly because of the mosquito's great reproductive capacity and genomic flexibility. Chemical control is increasingly restricted due to potential human toxicity, mortality in no target organisms, insecticide resistance, and other environmental impacts. Other strategies for mosquito control are desperately needed. The Sterile Insect Technique (SIT is a species-specific and environmentally benign method for insect population suppression, it is based on mass rearing, radiation mediated sterilization, and release of a large number of male insects. Releasing of Insects carrying a dominant lethal gene (RIDL offers a solution to many of the drawbacks of traditional SIT that have limited its application in mosquitoes while maintaining its environmentally friendly and species-specific utility. The self-limiting nature of sterile mosquitoes tends to make the issues related to field use of these somewhat less challenging than for self-spreading systems characteristic of population replacement strategies. They also are closer to field use, so might be appropriate to consider first. The prospect of genetic control methods against mosquito vectored human diseases is rapidly becoming a reality, many decisions will need to be made on a national, regional and international level regarding the biosafety, social, cultural and ethical aspects of the use and deployment of these vector control methods.

  16. Evolución de la Coqueluche en la Argentina a finales del siglo XX Pertussis: its evolution in Argentina at the end of the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Clara A. Riva Posse

    2005-03-01

    variation rates for 1969-2000 were -14.34 and for 1980-2000 -17.26; mortality annual mean variation rates for 1980-2000 was -10.41. Vaccination coverage in infants up to one year of age (3 doses was 44.4% in 1980; less than 60% until 1982 and higher than 80% after 1990. A highly significant inverse correlation was observed, between (a vaccine implementation, increase in its coverage, introduction of a fifth vaccine dose, and (b notification and mortality rates. It was observed during the study, that in our country there is a relatively little knowledge about disease occurrence in adults, and an apparent absence of population-based studies performed on the efficacy of erythromycin chemo profilaxis in epidemics outbreaks. Based on these data, strategies for a better surveillance and control of pertussis, are exposed.

  17. Extreme genetic diversity in asexual grass thrips populations.

    Science.gov (United States)

    Fontcuberta García-Cuenca, A; Dumas, Z; Schwander, T

    2016-05-01

    The continuous generation of genetic variation has been proposed as one of the main factors explaining the maintenance of sexual reproduction in nature. However, populations of asexual individuals may attain high levels of genetic diversity through within-lineage diversification, replicate transitions to asexuality from sexual ancestors and migration. How these mechanisms affect genetic variation in populations of closely related sexual and asexual taxa can therefore provide insights into the role of genetic diversity for the maintenance of sexual reproduction. Here, we evaluate patterns of intra- and interpopulation genetic diversity in sexual and asexual populations of Aptinothrips rufus grass thrips. Asexual A. rufus populations are found throughout the world, whereas sexual populations appear to be confined to few locations in the Mediterranean region. We found that asexual A. rufus populations are characterized by extremely high levels of genetic diversity, both in comparison with their sexual relatives and in comparison with other asexual species. Migration is extensive among asexual populations over large geographic distances, whereas close sexual populations are strongly isolated from each other. The combination of extensive migration with replicate evolution of asexual lineages, and a past demographic expansion in at least one of them, generated high local clone diversities in A. rufus. These high clone diversities in asexual populations may mimic certain benefits conferred by sex via genetic diversity and could help explain the extreme success of asexual A. rufus populations.

  18. Governmentality, biopower, and the debate over genetic enhancement.

    Science.gov (United States)

    McWhorter, Ladelle

    2009-08-01

    Although Foucault adamantly refused to make moral pronouncements or dictate moral principles or political programs to his readers, his work offers a number of tools and concepts that can help us develop our own ethical views and practices. One of these tools is genealogical analysis, and one of these concepts is "biopower." Specifically, this essay seeks to demonstrate that Foucault's concept of biopower and his genealogical method are valuable as we consider moral questions raised by genetic enhancement technologies. First, it examines contemporary debate over the development, marketing, and application of such technologies, suggesting that what passes for ethical deliberation is often little more than political maneuvering in a field where stakes are very high and public perceptions will play a crucial role in decisions about which technologies will be funded or disallowed. It goes on to argue that genuine ethical deliberation on these issues requires some serious investigation of their historical context. Accordingly, then, it takes up the oft-heard charge from critics that genetic enhancement technologies are continuous with twentieth-century eugenic projects or will usher in a new age of eugenics. Foucault explicitly links twentieth-century eugenics with the rise of biopower. Through review of some aspects of the twentieth-century eugenics movement alongside some of the rhetoric and claims of enhancement's modern-day proponents, the essay shows ways in which deployment of genetic enhancement technologies is and is not continuous with earlier deployments of biopower.

  19. Identification of management units using population genetic data

    NARCIS (Netherlands)

    Palsboll, Per J.; Berube, Martine; Allendorf, Fred W.

    2007-01-01

    The identification of management units (MUs) is central to the management of natural populations and is crucial for monitoring the effects of human activity upon species abundance. Here, we propose that the identification of MUs from population genetic data should be based upon the amount of genetic

  20. AMOVA-based clustering of population genetic data

    NARCIS (Netherlands)

    Meirmans, P.G.

    2012-01-01

    Determining the genetic structure of populations is becoming an increasingly important aspect of genetic studies. One of the most frequently used methods is the calculation of F-statistics using an Analysis of Molecular Variance (AMOVA). However, this has the drawback that the population hierarchy

  1. Population genetic diversity and fitness in multiple environments

    Directory of Open Access Journals (Sweden)

    McGreevy Thomas J

    2010-07-01

    Full Text Available Abstract Background When a large number of alleles are lost from a population, increases in individual homozygosity may reduce individual fitness through inbreeding depression. Modest losses of allelic diversity may also negatively impact long-term population viability by reducing the capacity of populations to adapt to altered environments. However, it is not clear how much genetic diversity within populations may be lost before populations are put at significant risk. Development of tools to evaluate this relationship would be a valuable contribution to conservation biology. To address these issues, we have created an experimental system that uses laboratory populations of an estuarine crustacean, Americamysis bahia with experimentally manipulated levels of genetic diversity. We created replicate cultures with five distinct levels of genetic diversity and monitored them for 16 weeks in both permissive (ambient seawater and stressful conditions (diluted seawater. The relationship between molecular genetic diversity at presumptive neutral loci and population vulnerability was assessed by AFLP analysis. Results Populations with very low genetic diversity demonstrated reduced fitness relative to high diversity populations even under permissive conditions. Population performance decreased in the stressful environment for all levels of genetic diversity relative to performance in the permissive environment. Twenty percent of the lowest diversity populations went extinct before the end of the study in permissive conditions, whereas 73% of the low diversity lines went extinct in the stressful environment. All high genetic diversity populations persisted for the duration of the study, although population sizes and reproduction were reduced under stressful environmental conditions. Levels of fitness varied more among replicate low diversity populations than among replicate populations with high genetic diversity. There was a significant correlation

  2. GENETICS OF INDO-EUROPEAN POPULATIONS: THE PAST, THE FUTURE

    OpenAIRE

    Balanovsky, Oleg; Utevska, Olga; Balanovska, Elena

    2013-01-01

    We describe our experience of comparing genetic and linguistic data in relation to the Indo-European problem. Our recent comparison of the genetic variation with lexicostatistical data on North Caucasian populations identified the parallel evolution of genes and languages; one can say that history of the populations was reflected in the linguistic and the genetic mirrors. For other linguistic families one can also expect this similarity, though it could be blurred by elite dominance and other...

  3. Genetic diversity of natural Hepatacodium miconioides populations in Zhejiang Province

    Institute of Scientific and Technical Information of China (English)

    LI Junmin; JIN Zexin

    2006-01-01

    Hepatacodium miconioides is the Class Ⅱ protected plant species in China.This paper studies the genetic diversity and differentiation of its nine natural populations in Zhejiang Province by using random amplified polymorphic DNA (RAPD) technique.Twelve random primers were selected in the amplification,and 164 repetitive loci were produced.The percentage of polymorphic loci in each H.miconioides population ranged from 14.60% to 27.44%,with an average of 20.73%.Among the test populations,Kuochangshan had the highest percentage of polymorphic loci,Simingshan took the second place,and Guanyinping had the lowest percentage.As estimated by Shannon index,the genetic diversity within H.miconioides populations accounted for 27.28% of the total genetic diversity,while that among H.miconioides populations accounted for 72.72%.The genetic differentiation among H.miconioides populations as estimated by Nei index was 0.715,7.This figure was generally consistent with that estimated by Shannon index,i.e.,the genetic differentiation among populations was relatively high,but that within populations was relatively low.The gene flow among H.miconioides populations was relatively low (0.198,7),and the genetic similarity ranged from 0.655,7 to 0.811,9,with an average of 0.730,6.The highest genetic distance among populations was 0.422,9,while the lowest was 0.208,3.All the results showed that there was a distinct genetic differentiation among H.miconioides populations.The genetic distance matrix of nine test populations was calculated using this method,and the clustering analysis was made using the unweighted pair group method with arithmetic mean (UPGMA).The cluster analysis suggested that the ninepopulations of H.miconioides in Zhejiang Province could be divided into two groups,the eastern Zhejiang group and the western Zhejiang group.

  4. Measuring differentiation among populations at different levels of genetic integration

    Directory of Open Access Journals (Sweden)

    Gregorius Hans-Rolf

    2008-09-01

    Full Text Available Abstract Background Most genetic studies of population differentiation are based on gene-pool frequencies. Population differences for gene associations that show up as deviations from Hardy-Weinberg proportions (homologous association or gametic disequilibria (non-homologous association are disregarded. Thus little is known about patterns of population differentiation at higher levels of genetic integration nor the causal forces. Results To fill this gap, a conceptual approach to the description and analysis of patterns of genetic differentiation at arbitrary levels of genetic integration (single or multiple loci, varying degrees of ploidy is introduced. Measurement of differentiation is based on the measure Δ of genetic distance between populations, which is in turn based on an elementary genic difference between individuals at any given level of genetic integration. It is proven that Δ does not decrease when the level of genetic integration is increased, with equality if the gene associations at the higher level follow the same function in both populations (e.g. equal inbreeding coefficients, no association between loci. The pattern of differentiation is described using the matrix of pairwise genetic distances Δ and the differentiation snail based on the symmetric population differentiation ΔSD. A measure of covariation compares patterns between levels. To show the significance of the observed differentiation among possible gene associations, a special permutation analysis is proposed. Applying this approach to published genetic data on oak, the differentiation is found to increase considerably from lower to higher levels of integration, revealing variation in the forms of gene association among populations. Conclusion This new approach to the analysis of genetic differentiation among populations demonstrates that the consideration of gene associations within populations adds a new quality to studies on population differentiation that is

  5. History of twentieth-century physics

    CERN Document Server

    Kapitza, Sergei P

    1995-01-01

    The meaning and message of the history of science will be discussed with relevance to XX century physics. This decisive period began in 1894-95 with the discoveries of the electron,X-rays and radioactivity,with the consequent development of relativity and quantumphysics. Connections of the development of science and society in XX century with culture and the influence on industry will be examined. Finally, the corruption of physics by the military will be considered. The influence of physics on chemistry and biology will be briefly treated and the impact of the approach and method of physics on modern thinking will be assessed. It should be kept in mind that the history of science is not a way of getting a simplified or adulterated presentation of the subject ,in this case of physics and so some understanding of general physics will be assumed. On the other hand, the broader generalisations of the history of ideas and events are illustrated (if not proven) by the facts (and myths) of science. Finally,as an e...

  6. Landmark experiments in twentieth-century physics

    CERN Document Server

    Trigg, George L

    2011-01-01

    Physics is very much an experimental science, but too often, students at the undergraduate level are not exposed to the reality of experimental physics ― i.e., what was done in a given experiment, why it was done, the background of physics against which the experiment was carried out and the changes in theory and knowledge that resulted. In this hook, the author helps to remedy the situation by presenting a variety of ""landmark"" experiments that have brought about significant alterations in our ideas about some aspect of nature. Among these scientific milestones are discoveries about the wa

  7. renal transplantation during the twentieth century

    African Journals Online (AJOL)

    2001-06-01

    Jun 1, 2001 ... femoral vessels and a cutaneous ureterostomy was performed. The transplanted ... period radiation was extensively used for immunosuppression. .... critically injured patients from road traffic accidents resulting in reduced ...

  8. Military Planning in the Twentieth Century

    Science.gov (United States)

    1986-01-01

    every turn by a horde of parliamenta- 45 ry carpers and journalist^."^’ There was more truth in the fact that rearmament in France (as in Great...Comparing the Operational Concept and the Defense,” ibid, Dec 1982, pp 13-19; James C. Barbara and Robert F. Brown, “Deep Thrust on the Extended

  9. Misreading Science in the Twentieth Century.

    Science.gov (United States)

    Budd, John M.

    2001-01-01

    Considers textual aspects of scientific communication and problems for reception presented by the complex dynamics of communicating scientific work. Discusses scientific work based on fraud or misconduct and disputes about the nature of science, and applies reception theory and reader-response criticism to understand variations in readings of the…

  10. Gauge Theories in the Twentieth Century

    CERN Document Server

    2001-01-01

    By the end of the 1970s, it was clear that all the known forces of nature (including, in a sense, gravity) were examples of gauge theories , characterized by invariance under symmetry transformations chosen independently at each position and each time. These ideas culminated with the finding of the W and Z gauge bosons (and perhaps also the Higgs boson). This important book brings together the key papers in the history of gauge theories, including the discoveries of: the role of gauge transformations in the quantum theory of electrically charged particles in the 1920s; nonabelian gauge groups

  11. Presentation: Twentieth-century Dictatorships and Religion

    Directory of Open Access Journals (Sweden)

    Jan Nelis

    2009-12-01

    Full Text Available Este dossier agrupa trabajos que cubren una amplia zona geográfica, ofreciendo diferentes puntos de vista sobre aspectos concernientes a la relación entre políticas dictatoriales y religión. El resultado final es ocho artículos que abordan la cuestión en cuatro continentes: Asia, África, América y Europa. Por la diversidad de enfoques, los artículos tratan, desde perspectivas diferentes, las actitudes “pragmáticas” coloniales y postcoloniales hacia la religión en África (Grandhomme y Kroubo Dagnini, la identidad religiosa africana (Chande, el uso de la religión como una fuente de moral y ética en Argentina (Cousins y Francia (Stevens, el punto de tensión entre la religión y política tradicionales y el mito en China (Lee e Italia (Nelis, y las actitudes de la dictadura hacia la identidad religiosa en España (Beck.____________________ABSTRACT:This dossier contains essays that cover a broad geographic area, offering different points of view on various aspects concerning the relation between dictatorship policies and religion. The final result are eight articles, which deal with the situation on four continents: Asia, Africa, America and Europe. Presenting a great variety of approaches, the articles show different views on the “pragmatic” colonial and post-colonial attitudes towards religion in Africa (Grandhomme and Kroubo Dagnini, African religious identity (Chande, the use of religion as a source of morals and ethics in Argentina (Cousins and France (Stevens, the point of tension between traditional religion and politics and the myth in China (Lee and Italy (Nelis and the dictatorship’s attitude towards the religious identity in Spain (Beck.

  12. Twentieth Century Books Influencing American Education

    Science.gov (United States)

    McCaul, Robert L.

    1977-01-01

    Discusses: "Educational Psychology," Thorndike; "Medical Education," Flexner; "Democracy and Education," Dewey; "The Measurement of Intelligence," Terman; "Public Education," Cubberley; "The Thirty-Ninth Yearbook of the National Society for the Study of Education, Intelligence: Its Nature and Nurture;" and, "Why Johnny Can't Read," Flesch. (JM)

  13. Military Planning in the Twentieth Century

    Science.gov (United States)

    1984-10-01

    and Fred Freed. The decision to drop the bomb. New York: Coward-McCann, 1965. (UA 23 .G51) 27 Greenfield, Kent R. American strategy in World War II...Air University, 1974. (UGB 907 .A42 5194) Brauers , W. X. Systems analysis, planning and decision models: with special reference to national defense

  14. Revolutions in twentieth-century physics

    CERN Document Server

    Griffiths, David J

    2013-01-01

    The conceptual changes brought by modern physics are important, radical and fascinating, yet they are only vaguely understood by people working outside the field. Exploring the four pillars of modern physics – relativity, quantum mechanics, elementary particles and cosmology – this clear and lively account will interest anyone who has wondered what Einstein, Bohr, Schrödinger and Heisenberg were really talking about. The book discusses quarks and leptons, antiparticles and Feynman diagrams, curved space-time, the Big Bang and the expanding Universe. Suitable for undergraduate students in non-science as well as science subjects, it uses problems and worked examples to help readers develop an understanding of what recent advances in physics actually mean.

  15. Biology Curriculum in Twentieth-Century Spain.

    Science.gov (United States)

    Barbera, Oscar; Zanon, Beatriz; Perez-Pla, Jose Francisco

    1999-01-01

    Reviews 100 years of history and focuses on the relationship between socially controversial biological issues and the decision-making procedures in the construction of the national curriculum. Contains 39 references. (DDR)

  16. The Twentieth Century Fund Annual Report 1971.

    Science.gov (United States)

    Twentieth Century Fund, New York, NY.

    Research continued and new studies were launched in four major areas: communications, urban problems, politics, and economic issues. The foci of these studies are described briefly. Projects in communications are examining flows of news, media monopoly, press freedoms under pressure, public affairs broadcasting, press councils, political access to…

  17. Companion to science in the twentieth century

    CERN Document Server

    Pestre, Dominique

    2003-01-01

    With over forty chapters, written by leading scholars, this comprehensive volume represents the best work in America, Europe and Asia. Geographical diversity of the authors is reflected in the different perspectives devoted to the subject, and all major disciplinary developments are covered. There are also sections concerning the countries that have made the most significant contributions, the relationship between science and industry, the importance of instrumentation, and the cultural influence of scientific modes of thought. Students and professionals will come to appreciate how, and why, science has developed - as with any other human activity, it is subject to the dynamics of society and politics.

  18. How Ebola impacts genetics of Western lowland gorilla populations.

    Directory of Open Access Journals (Sweden)

    Pascaline J Le Gouar

    Full Text Available BACKGROUND: Emerging infectious diseases in wildlife are major threats for both human health and biodiversity conservation. Infectious diseases can have serious consequences for the genetic diversity of populations, which could enhance the species' extinction probability. The Ebola epizootic in western and central Africa induced more than 90% mortality in Western lowland gorilla population. Although mortality rates are very high, the impacts of Ebola on genetic diversity of Western lowland gorilla have never been assessed. METHODOLOGY/PRINCIPAL FINDINGS: We carried out long term studies of three populations of Western lowland gorilla in the Republic of the Congo (Odzala-Kokoua National Park, Lossi gorilla sanctuary both affected by Ebola and Lossi's periphery not affected. Using 17 microsatellite loci, we compared genetic diversity and structure of the populations and estimate their effective size before and after Ebola outbreaks. Despite the effective size decline in both populations, we did not detect loss in genetic diversity after the epizootic. We revealed temporal changes in allele frequencies in the smallest population. CONCLUSIONS/SIGNIFICANCE: Immigration and short time elapsed since outbreaks could explain the conservation of genetic diversity after the demographic crash. Temporal changes in allele frequencies could not be explained by genetic drift or random sampling. Immigration from genetically differentiated populations and a non random mortality induced by Ebola, i.e., selective pressure and cost of sociality, are alternative hypotheses. Understanding the influence of Ebola on gorilla genetic dynamics is of paramount importance for human health, primate evolution and conservation biology.

  19. Genetic consequences of population decline in the Danish population of the little owl (Athene noctua)

    DEFF Research Database (Denmark)

    Pertoldi, Cino; Pellegrino, Irene; Cucco, Maroc

    2012-01-01

    Background: Danish populations of the little owl (Athene noctua) have experienced dramaticdeclines in size over the past century. Before 1960 the little owl population was abundantin Denmark (estimated N>2000), but between 1960 and 1980 the population declinedrapidly, and since 1980 the little owl...... population has survived only in small and fragmentedareas. Question: Is the decline in population size associated with reduced genetic variation in theseDanish populations of the little owl? Are the populations genetically fragmented?Field site: Samples were collected from birds in Denmark (from 57457″N...... relatively little genetic variability, with more recent onesshowing even less. In addition, pairwise FST values showed evidence for genetic substructuringwith small but significant genetic differences between the extant population and the extinct owlpopulations on the Danish isle of Funen. The modest loss...

  20. Molecular genetic diversity and genetic structure of Vietnamese indigenous pig populations

    DEFF Research Database (Denmark)

    Pham, L. D.; Do, Duy Ngoc; Nam, L. Q.

    2014-01-01

    The study characterized genetic diversity and genetic structure of five indigenous pig populations (Ha Lang, Muong Te, Mong Cai, Lung and Lung Pu), two wild pig populations (Vietnamese and Thai wild pigs) and an exotic pig breed (Yorkshire) using FAO/ISAG recommended 16 microsatellite markers...... eight populations into four groups including Yorkshire, two wild populations, Mong Cai population and a group of four other indigenous populations. The Bayesian clustering with the admixture model implemented in Structure 2.1 indicated seven possible homogenous clusters among eight populations. From 79......% (Ha Lang) to 98% (Mong Cai). individuals in indigenous pigs were assigned to their own populations. The results confirmed high level of genetic diversity and shed a new light on genetic structure of Vietnam indigenous pig populations....

  1. Detailed genetic structure of European bitterling populations in Central Europe

    Directory of Open Access Journals (Sweden)

    Veronika Bartáková

    2015-11-01

    Full Text Available The European bitterling (Rhodeus amarus is a small cyprinid fish whose populations declined markedly between 1950 and 1980. However, its range currently expands, partly due to human-assisted introductions. We determined the genetic variability and detailed spatial structure among bitterling populations in Central Europe and tested alternative hypotheses about colonization of this area. Twelve polymorphic microsatellite loci on a large sample of 688 individuals had been used to analyse genetic variability and population structure. Samples originated from 27 localities with emphasis on area of the Czech Republic where three major sea drainages (Black, Baltic, and Northern Sea meet. Highly variable level of intrapopulation genetic variability had generally been detected and a recent decrease in numbers (“bottleneck” had been indicated by genetic data among six populations. High level of interpopulation differentiation was identified even within the basins. There was a significant role of genetic drift and indications of low dispersal ability of R. amarus. Surprisingly, the Odra River was inhabited by two distinct populations without any genetic signatures of a secondary contact. Czech part of the Odra (Baltic basin was colonized from the Danubian refugium (similarly to adjacent Danubian basin rivers including the Morava, while Polish part of the Odra was genetically similar to the populations in the Vistula River (Baltic basin, that has been colonized by a different (Eastern phylogeographic lineage of R. amarus. Most Czech R. amarus populations were colonized from the Danubian refugium, suggesting potential for a human-mediated colonization of the Odra or Elbe Rivers by R. amarus. One Elbe basin population was genetically mixed from the two (Danubian and Eastern phylogeographic lineages. In general the Czech populations of R. amarus were genetically stable except for a single population which has probably been recently introduced. This research

  2. Population genetic structure of Aedes albopictus in Penang, Malaysia.

    Science.gov (United States)

    Zawani, M K N; Abu, H A; Sazaly, A B; Zary, S Y; Darlina, M N

    2014-10-07

    The mosquito Aedes albopictus is indigenous to Southeast Asian and is a vector for arbovirus diseases. Studies examining the population genetics structure of A. albopictus have been conducted worldwide; however, there are no documented reports on the population genetic structure of A. albopictus in Malaysia, particularly in Penang. We examined the population genetics of A. albopictus based on a 445-base pair segment of the mitochondrial DNA cytochrome oxidase 1 gene among 77 individuals from 9 localities representing 4 regions (Seberang Perai Utara, Seberang Perai Tengah, Northeast, and Southwest) of Penang. A total of 37 haplotypes were detected, including 28 unique haplotypes. The other 9 haplotypes were shared among various populations. These shared haplotypes reflect the weak population genetic structure of A. albopictus. The phylogenetic tree showed a low bootstrap value with no genetic structure, which was supported by minimum spanning network analysis. Analysis of mismatch distribution showed poor fit of equilibrium distribution. The genetic distance showed low genetic variation, while pairwise FST values showed no significant difference between all regions in Penang except for some localities. High haplotype diversity and low nucleotide diversity was observed for cytochrome oxidase 1 mtDNA. We conclude that there is no population genetic structure of A. albopictus mosquitoes in the Penang area.

  3. La editorial Ricordi y su aportación a la publicidad italiana de principios del siglo XX / The publisher Ricordi and his contribution to the Italian advertising early twentieth century

    Directory of Open Access Journals (Sweden)

    Rut Francia Ferrero

    2013-09-01

    Full Text Available El objeto de estudio de la presente investigación es el nacimiento de las campañas publicitarias gráficas orquestadas por la fructífera colaboración entre empresarios, editores e ilustradores entre los siglos XIX y XX en Italia. El estudio se centra en la Casa Editorial Ricordi porque fue la creadora e impulsora del moderno cartel artístico y publicitario italiano, con un vasta producción de ejemplares, hoy considerados obras maestras del género. La etapa de oro del cartel italiano coincide, no por casualidad, con el predominio técnico y artístico de esta empresa en Italia que nada tenía que envidiar a sus competidoras francesas (como la prestigiosa Imprimerie Chaix parisina, tan querida por Jules Chéret, alemanas o inglesas. El período analizado (1890-1914 es el de mayor actividad y esplendor artístico en las artes gráficas. Son los años de los primeros pasos en el campo de la publicidad. Como en todos los comienzos, abundan las ideas, la energía, la ingenuidad y las ganas de experimentar. Es un tiempo lleno de cambios: la transformación económica, social e industrial que vivió Europa en un lapso tan corto de  tiempo es probablemente la mayor de su historia.The purpose of this research is the birth of graphic advertising campaigns orchestrated by the fruitful collaboration between employers, publishers and illustrators between the nineteenth and twentieth centuries in Italy. The study focuses on the Ricordi publishing house because it was the creator and driving force of the modern Italian poster art and advertising with a vast production of copies, today considered masterpieces of the genre. The golden age of Italian poster coincides, not coincidentally, with the technical and artistic dominance of this company in Italy that had nothing to envy their French competitors (including the prestigious Paris Imprimerie Chaix, so beloved by Jules Cheret, German or England. The period analyzed (1890-1914 is the most active and

  4. Las revistas de empresa en España: algunos ejemplos de house organ desde principios del siglo XX / House Organ in Spain: some examples from the early twentieth century

    Directory of Open Access Journals (Sweden)

    Jesús Reina Estevez

    2015-11-01

    Full Text Available Sobre los house organ o revista de empresa parece haberse escrito muy poco y siempre desde su dimensión técnica, obviando su evolución histórica. Pese a ser una técnica con fuerte tradición en otros países como EEUU, Inglaterra o Francia desde finales del siglo XIX, en España su estudio ha pasado casi desapercibido. El principal objetivo de esta investigación es encontrar algunas manifestaciones de este instrumento en las organizaciones patrias desde principios del pasado siglo XX, para confeccionar una lista de ejemplos reales sin carácter exhaustivo. Para alcanzar los resultados se parte de una revisión bibliográfica de las primeras obras sobre publicidad que se publicaron en nuestro país, que dará lugar al estudio de los manuales sobre relaciones públicas que se han editado posteriormente. Esta metodología se completa con la consulta a hemerotecas y las, comúnmente conocidas, como librerías de viejo o librerías de segunda mano, donde a día de hoy se atesoran algunos ejemplares de house organ que han sobrevivido al paso del tiempo. / It´s have written about house organ very little and always from technical dimension, ignoring the historical evolution. Despite being a technique with a strong tradition in other countries like USA, England or France since the late nineteenth century, in Spain study it has gone unnoticed until now. The main objective of this research focuses on finding some manifestations of this instrument in the patriotic organizations since the beginning of the twentieth century, to compile a list of real examples without limitation. To achieve results is part of a literature review of the first works on advertising that were published in our country that will lead to the study of public relations manuals that have been subsequently released. This methodology is supplemented by consulting newspaper archives and used bookstores, where today some specimens of house organs have survived the passage of time.

  5. Genetic variation and population structure in native Americans.

    Directory of Open Access Journals (Sweden)

    Sijia Wang

    2007-11-01

    Full Text Available We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower genetic diversity and greater differentiation than populations from other continental regions. We observe gradients both of decreasing genetic diversity as a function of geographic distance from the Bering Strait and of decreasing genetic similarity to Siberians--signals of the southward dispersal of human populations from the northwestern tip of the Americas. We also observe evidence of: (1 a higher level of diversity and lower level of population structure in western South America compared to eastern South America, (2 a relative lack of differentiation between Mesoamerican and Andean populations, (3 a scenario in which coastal routes were easier for migrating peoples to traverse in comparison with inland routes, and (4 a partial agreement on a local scale between genetic similarity and the linguistic classification of populations. These findings offer new insights into the process of population dispersal and differentiation during the peopling of the Americas.

  6. Genetic analysis in the Collaborative Cross breeding population.

    Science.gov (United States)

    Philip, Vivek M; Sokoloff, Greta; Ackert-Bicknell, Cheryl L; Striz, Martin; Branstetter, Lisa; Beckmann, Melissa A; Spence, Jason S; Jackson, Barbara L; Galloway, Leslie D; Barker, Paul; Wymore, Ann M; Hunsicker, Patricia R; Durtschi, David C; Shaw, Ginger S; Shinpock, Sarah; Manly, Kenneth F; Miller, Darla R; Donohue, Kevin D; Culiat, Cymbeline T; Churchill, Gary A; Lariviere, William R; Palmer, Abraham A; O'Hara, Bruce F; Voy, Brynn H; Chesler, Elissa J

    2011-08-01

    Genetic reference populations in model organisms are critical resources for systems genetic analysis of disease related phenotypes. The breeding history of these inbred panels may influence detectable allelic and phenotypic diversity. The existing panel of common inbred strains reflects historical selection biases, and existing recombinant inbred panels have low allelic diversity. All such populations may be subject to consequences of inbreeding depression. The Collaborative Cross (CC) is a mouse reference population with high allelic diversity that is being constructed using a randomized breeding design that systematically outcrosses eight founder strains, followed by inbreeding to obtain new recombinant inbred strains. Five of the eight founders are common laboratory strains, and three are wild-derived. Since its inception, the partially inbred CC has been characterized for physiological, morphological, and behavioral traits. The construction of this population provided a unique opportunity to observe phenotypic variation as new allelic combinations arose through intercrossing and inbreeding to create new stable genetic combinations. Processes including inbreeding depression and its impact on allelic and phenotypic diversity were assessed. Phenotypic variation in the CC breeding population exceeds that of existing mouse genetic reference populations due to both high founder genetic diversity and novel epistatic combinations. However, some focal evidence of allele purging was detected including a suggestive QTL for litter size in a location of changing allele frequency. Despite these inescapable pressures, high diversity and precision for genetic mapping remain. These results demonstrate the potential of the CC population once completed and highlight implications for development of related populations.

  7. Assessment of Genetic Diversity and Population Genetic Structure of Corylus mandshurica in China Using SSR Markers.

    Directory of Open Access Journals (Sweden)

    Jian-Wei Zong

    Full Text Available Corylus mandshurica, also known as pilose hazelnut, is an economically and ecologically important species in China. In this study, ten polymorphic simple sequence repeat (SSR markers were applied to evaluate the genetic diversity and population structure of 348 C. mandshurica individuals among 12 populations in China. The SSR markers expressed a relatively high level of genetic diversity (Na = 15.3, Ne = 5.6604, I = 1.8853, Ho = 0.6668, and He = 0.7777. According to the coefficient of genetic differentiation (Fst = 0.1215, genetic variation within the populations (87.85% were remarkably higher than among populations (12.15%. The average gene flow (Nm = 1.8080 significantly impacts the genetic structure of C. mandshurica populations. The relatively high gene flow (Nm = 1.8080 among wild C. mandshurica may be caused by wind-pollinated flowers, highly nutritious seeds and self-incompatible mating system. The UPGMA (unweighted pair group method of arithmetic averages dendrogram was divided into two main clusters. Moreover, the results of STRUCTURE analysis suggested that C. mandshurica populations fell into two main clusters. Comparison of the UPGMA dendrogram and the Bayesian STRUCTURE analysis showed general agreement between the population subdivisions and the genetic relationships among populations of C. mandshurica. Group I accessions were located in Northeast China, while Group II accessions were in North China. It is worth noting that a number of genetically similar populations were located in the same geographic region. The results further showed that there was obvious genetic differentiation among populations from Northeast China to North China. Results from the Mantel test showed a weak but still significant positive correlation between Nei's genetic distance and geographic distance (km among populations (r = 0.419, P = 0.005, suggesting that genetic differentiation in the 12 C. mandshurica populations might be related to geographic

  8. An Exploration into Twentieth-Century Poetics: A Study of Poetry On & Off the Page by Marjorie Perloff%从玛乔瑞·帕洛夫的《文里文外之诗》观20世纪诗学

    Institute of Scientific and Technical Information of China (English)

    陈小红

    2011-01-01

    玛乔瑞·帕洛夫的《文里文外之诗》描述20世纪诗学的演变,并追溯其与历史、文化和社会的共同演化。本文主要从在四个方面探讨帕洛夫所论述的20世纪的诗学:语言游戏、自发式写作、相对自由的形式、后现代性。帕洛夫不仅利用诗歌文本,而且还利用音乐、绘画、以及摄影等领域的作品来探讨20世纪的诗学观念。帕洛夫认为,20世纪的诗学最大成就在于开启了一种新的思维方式,这是《文里文外之诗》的主要发展脉络。%Poetry On Off the Page by Marjorie Perloff maps the transformations of twentieth-century poetics, which has evolved in the dialogue with history, culture, and society. This article approaches the poetics in the following four aspects: game of words, spontaneous writing, relatively free form and postmodernity. Perloff extends her exploration into twentieth-century poetics from poetry to music, painting and photography. In her opinion, the greatest achievement of twentieth-century poetics lies in opening a new way of thinking, which is the major developing line of Poetry On Off the Page.

  9. The genetic structure of a relict population of wood frogs

    Science.gov (United States)

    Scherer, Rick; Muths, Erin; Noon, Barry; Oyler-McCance, Sara

    2012-01-01

    Habitat fragmentation and the associated reduction in connectivity between habitat patches are commonly cited causes of genetic differentiation and reduced genetic variation in animal populations. We used eight microsatellite markers to investigate genetic structure and levels of genetic diversity in a relict population of wood frogs (Lithobates sylvatica) in Rocky Mountain National Park, Colorado, where recent disturbances have altered hydrologic processes and fragmented amphibian habitat. We also estimated migration rates among subpopulations, tested for a pattern of isolation-by-distance, and looked for evidence of a recent population bottleneck. The results from the clustering algorithm in Program STRUCTURE indicated the population is partitioned into two genetic clusters (subpopulations), and this result was further supported by factorial component analysis. In addition, an estimate of FST (FST = 0.0675, P value \\0.0001) supported the genetic differentiation of the two clusters. Estimates of migration rates among the two subpopulations were low, as were estimates of genetic variability. Conservation of the population of wood frogs may be improved by increasing the spatial distribution of the population and improving gene flow between the subpopulations. Construction or restoration of wetlands in the landscape between the clusters has the potential to address each of these objectives.

  10. Implications of population structure and ancestry on asthma genetic studies.

    Science.gov (United States)

    Ortega, Victor E; Meyers, Deborah A

    2014-10-01

    The frequency and severity of asthma differ between different racial and ethnic groups. An understanding of the genetic basis for these differences could constitute future genetic biomarker panels for predicting asthma risk and progression in individuals from different ethnic groups. The recent mixing of different ancestries during the European colonization of the Americas and the African slave trade has resulted in the complex population structures identified in different ethnic groups. These population structures represent varying degrees of genetic diversity which impacts the allele frequency of individual variants and, thus, how the gene variation is utilized in genetic association studies. In this review, we will discuss the basis for the complex population structures of modern human genomes and the impact of genetic diversity on genetic studies in different ethnic groups. We will also highlight the potential for admixture and rare variant-based genetic studies to identify novel genetic loci for asthma susceptibility and severity. The ability to account for the consequences of genetic diversity in different racial and ethnic groups will be critical in developing genetic profiles for personalized or precision medicine approaches tailored to asthmatic patients from different ethnic groups.

  11. Population structure and genetic diversity of native and invasive populations of Solanum rostratum (Solanaceae.

    Directory of Open Access Journals (Sweden)

    Jiali Zhao

    Full Text Available AIMS: We investigate native and introduced populations of Solanum rostratum, an annual, self-compatible plant that has been introduced around the globe. This study is the first to compare the genetic diversity of Solanum rostratum between native and introduced populations. We aim to (1 determine the level of genetic diversity across the studied regions; (2 explore the likely origins of invasive populations in China; and (3 investigate whether there is the evidence of multiple introductions into China. METHODS: We genotyped 329 individuals at 10 microsatellite loci to determine the levels of genetic diversity and to investigate population structure of native and introduced populations of S. rostratum. We studied five populations in each of three regions across two continents: Mexico, the U.S.A. and China. IMPORTANT FINDINGS: We found the highest genetic diversity among Mexican populations of S. rostratum. Genetic diversity was significantly lower in Chinese and U.S.A. populations, but we found no regional difference in inbreeding coefficients (F IS or population differentiation (F ST. Population structure analyses indicate that Chinese and U.S.A. populations are more closely related to each other than to sampled Mexican populations, revealing that introduced populations in China share an origin with the sampled U.S.A. populations. The distinctiveness between some introduced populations indicates multiple introductions of S. rostratum into China.

  12. Reintroductions and genetic introgression from domestic pigs have shaped the genetic population structure of Northwest European wild boar

    NARCIS (Netherlands)

    Goedbloed, D.J.; Hooft, van W.F.; Megens, H.J.W.C.; Langenbeck, K.; Lutz, W.; Crooijmans, R.P.M.A.; Wieren, van S.E.; Ydenberg, R.C.; Prins, H.H.T.

    2013-01-01

    Background: Population genetic studies focus on natural dispersal and isolation by landscape barriers as the main drivers of genetic population structure. However, anthropogenic factors such as reintroductions, translocations and wild x domestic hybridization may also have strong effects on genetic

  13. Noninvasive genetics provides insights into the population size and genetic diversity of an Amur tiger population in China.

    Science.gov (United States)

    Wang, Dan; Hu, Yibo; Ma, Tianxiao; Nie, Yonggang; Xie, Yan; Wei, Fuwen

    2016-01-01

    Understanding population size and genetic diversity is critical for effective conservation of endangered species. The Amur tiger (Panthera tigris altaica) is the largest felid and a flagship species for wildlife conservation. Due to habitat loss and human activities, available habitat and population size are continuously shrinking. However, little is known about the true population size and genetic diversity of wild tiger populations in China. In this study, we collected 55 fecal samples and 1 hair sample to investigate the population size and genetic diversity of wild Amur tigers in Hunchun National Nature Reserve, Jilin Province, China. From the samples, we determined that 23 fecal samples and 1 hair sample were from 7 Amur tigers: 2 males, 4 females and 1 individual of unknown sex. Interestingly, 2 fecal samples that were presumed to be from tigers were from Amur leopards, highlighting the significant advantages of noninvasive genetics over traditional methods in studying rare and elusive animals. Analyses from this sample suggested that the genetic diversity of wild Amur tigers is much lower than that of Bengal tigers, consistent with previous findings. Furthermore, the genetic diversity of this Hunchun population in China was lower than that of the adjoining subpopulation in southwest Primorye Russia, likely due to sampling bias. Considering the small population size and relatively low genetic diversity, it is urgent to protect this endangered local subpopulation in China.

  14. Genetic variation and population history of three Carassius auratus populations in Huaihe River, China.

    Science.gov (United States)

    Chen, Wei; Zhao, Yuanjun; Yang, Chengzhong

    2016-11-01

    In order to investigate the relationships of drainage history of Huaihe River with the genetic history of Carassius auratus along the river, we examined the genetic variations and population histories of three wild C. auratus populations in Huaihe River based on the D-loop gene. The results showed that their nucleotide and haplotype diversities were ranged from 0.00268 to 0.00651 and from 0.863 to 0.902, respectively, and their genetic distance was quite small. The analysis of molecular variance demonstrated that a frequent inter-population connection and large historic gene flows occurred among the three populations. Demographic analysis indicated that expansions had been happened in three populations. After investigating the historic process of the Huaihe River, we presumed that both nature and artificial factors may play important roles in shaping the genetic structure of the three populations. The present study also provided genetic information of C. auratus for further conservation of its germplasm resources.

  15. Genetic Variation of Host Populations of Liriomyza sativae Blanchard

    Institute of Scientific and Technical Information of China (English)

    WANG Li-ping; DU Yu-zhou; HE Ya-ting; ZHENG Fu-shan; LU Zi-qiang

    2008-01-01

    In this study, partial sequences of the mitochondrial cytochrome oxidase subunit Ⅰ (mtDNA-COI) gene and the ribosomal internal transcribed spacer 1 (rDNA-ITS1) gene, isolated from five artificial populations of Liriomyza sativae (Diptera:Agromyzidae), were sequenced and compared, to analyze their genetic variation. Analysis of the mtDNA-CO1 gene showed that a low genetic variation was detected among the five populations and only five variable sites were found in the nucleotide sequences. Most of the observed variations that occurred within the populations were because of nucleotide transitions, whereas, the interpopulation variation was because of the differences in haplotype frequencies occurring among the host populations. Analysis of the rDNA-ITS1 gene revealed a small diversity in the five host populations. The trend of genetic differentiation in the host populations was consistent with the preference of L. sativae to the plant hosts.

  16. Experimental Population Genetics in the Introductory Genetics Laboratory Using "Drosophila" as a Model Organism

    Science.gov (United States)

    Johnson, Ronald; Kennon, Tillman

    2009-01-01

    Hypotheses of population genetics are derived and tested by students in the introductory genetics laboratory classroom as they explore the effects of biotic variables (physical traits of fruit flies) and abiotic variables (island size and distance) on fruit fly populations. In addition to this hypothesis-driven experiment, the development of…

  17. Experimental Population Genetics in the Introductory Genetics Laboratory Using "Drosophila" as a Model Organism

    Science.gov (United States)

    Johnson, Ronald; Kennon, Tillman

    2009-01-01

    Hypotheses of population genetics are derived and tested by students in the introductory genetics laboratory classroom as they explore the effects of biotic variables (physical traits of fruit flies) and abiotic variables (island size and distance) on fruit fly populations. In addition to this hypothesis-driven experiment, the development of…

  18. The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape

    NARCIS (Netherlands)

    Dobon, B.; Hassan, H.Y.; Laayouni, H.; Luisi, P.; Ricano-Ponce, I.; Zhernakova, A.; Wijmenga, C.; Tahir, H.; Comas, D.; Netea, M.G.; Bertranpetit, J.

    2015-01-01

    East Africa is a strategic region to study human genetic diversity due to the presence of ethnically, linguistically, and geographically diverse populations. Here, we provide new insight into the genetic history of populations living in the Sudanese region of East Africa by analysing nine ethnic gro

  19. Genetic consequences of population decline in the Danish population of the little owl (Athene noctua)

    DEFF Research Database (Denmark)

    Pertoldi, Cino; Pellegrino, Irene; Cucco, Maroc

    2012-01-01

    Background: Danish populations of the little owl (Athene noctua) have experienced dramaticdeclines in size over the past century. Before 1960 the little owl population was abundantin Denmark (estimated N>2000), but between 1960 and 1980 the population declinedrapidly, and since 1980 the little owl...... population has survived only in small and fragmentedareas. Question: Is the decline in population size associated with reduced genetic variation in theseDanish populations of the little owl? Are the populations genetically fragmented?Field site: Samples were collected from birds in Denmark (from 57457″N...

  20. Genetic diversity in wild populations of Paulownia fortune.

    Science.gov (United States)

    Li, H Y; Ru, G X; Zhang, J; Lu, Y Y

    2014-11-01

    The genetic diversities of 16 Paulownia fortunei populations involving 143 individuals collected from 6 provinces in China were analyzed using amplified fragment length polymorphism (AFLP). A total of 9 primer pairs with 1169 polymorphic loci were screened out, and each pair possessed 132 bands on average. The percentage of polymorphic bands (98.57%), the effective number of alleles (1.2138-1.2726), Nei's genetic diversity (0.1566-0.1887), and Shannon's information index (0.2692-0.3117) indicated a plentiful genetic diversity and different among Paulownia fortunei populations. The genetic differentiation coefficient between populations was 0.2386, while the gene flow was 1.0954, and the low gene exchange promoted genetic differentiation. Analysis of variance indicated that genetic variation mainly occurred within populations (81.62% of total variation) rather than among populations (18.38%). The 16 populations were divided by unweighted pair-group method with arithmetic means (UPGMA) into 4 groups with obvious regionalism, in which the populations with close geographical locations (latitude) were clustered together.

  1. GESP: A computer program for modeling genetic effective population size, inbreeding, and divergence in substructured populations.

    Science.gov (United States)

    Olsson, Fredrik; Laikre, Linda; Hössjer, Ola; Ryman, Nils

    2017-03-24

    The genetically effective population size (Ne) is of key importance for quantifying rates of inbreeding and genetic drift, and is often used in conservation management to set targets for genetic viability. The concept was developed for single, isolated populations and the mathematical means for analyzing the expected Ne in complex, subdivided populations have previously not been available. We recently developed such analytical theory and central parts of that work have now been incorporated into a freely available software tool presented here. GESP (Genetic Effective population size, inbreeding, and divergence in Substructured Populations) is R-based and designed to model short and long term patterns of genetic differentiation and effective population size of subdivided populations. The algorithms performed by GESP allow exact computation of global and local inbreeding and eigenvalue effective population size, predictions of genetic divergence among populations (GST) as well as departures from random mating (FIS, FIT) while varying i) subpopulation census and effective size, separately or including trend of the global population size, ii) rate and direction of migration between all pairs of subpopulations, iii) degree of relatedness and divergence among subpopulations, iv) ploidy (haploid or diploid), and v) degree of selfing. Here, we describe GESP and exemplify its use in conservation genetics modeling. This article is protected by copyright. All rights reserved.

  2. Genetic Variation Within and Among Populations of Delmarva Fox Squirrels

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The objective of this study was to provide important information about genetic variation in populations of the Delmarva Fox Squirrel in the context of a more general...

  3. Genetic structure in four West African population groups.

    Science.gov (United States)

    Adeyemo, Adebowale A; Chen, Guanjie; Chen, Yuanxiu; Rotimi, Charles

    2005-06-24

    Africa contains the most genetically divergent group of continental populations and several studies have reported that African populations show a high degree of population stratification. In this regard, it is important to investigate the potential for population genetic structure or stratification in genetic epidemiology studies involving multiple African populations. The presences of genetic sub-structure, if not properly accounted for, have been reported to lead to spurious association between a putative risk allele and a disease. Within the context of the Africa America Diabetes Mellitus (AADM) Study (a genetic epidemiologic study of type 2 diabetes mellitus in West Africa), we have investigated population structure or stratification in four ethnic groups in two countries (Akan and Gaa-Adangbe from Ghana, Yoruba and Igbo from Nigeria) using data from 372 autosomal microsatellite loci typed in 493 unrelated persons (986 chromosomes). There was no significant population genetic structure in the overall sample. The smallest probability is associated with an inferred cluster of 1 and little of the posterior probability is associated with a higher number of inferred clusters. The distribution of members of the sample to inferred clusters is consistent with this finding; roughly the same proportion of individuals from each group is assigned to each cluster with little variation between the ethnic groups. Analysis of molecular variance (AMOVA) showed that the between-population component of genetic variance is less than 0.1% in contrast to 99.91% for the within population component. Pair-wise genetic distances between the four ethnic groups were also very similar. Nonetheless, the small between-population genetic variance was sufficient to distinguish the two Ghanaian groups from the two Nigerian groups. There was little evidence for significant population substructure in the four major West African ethnic groups represented in the AADM study sample. Ethnicity

  4. Genetic structure of fragmented November moth (Lepidoptera: Geometridae) populations in farmland

    DEFF Research Database (Denmark)

    Wynne, Ian Robert; Loxdale, Hugh D.; Brookes, Cliff P.

    2003-01-01

    allozymes, conservation genetics, Epirrita dilutata, Epirrita christyi, molecular markers, habitat fragmentation, population genetic structure......allozymes, conservation genetics, Epirrita dilutata, Epirrita christyi, molecular markers, habitat fragmentation, population genetic structure...

  5. Genetic diversity and population structure of maize landraces from ...

    African Journals Online (AJOL)

    pc

    2016-11-02

    Nov 2, 2016 ... diversity and genetic structure of 35 maize accessions using 10 microsatellite markers. These accessions ... In addition, they provide new sources of resistance to ..... http://taylor0.biology.ucla.edu/structureHarvester/.The .... environment and in other areas. ..... Molecular population genetics and evolution. In:.

  6. Thirty years of tick population genetics: a comprehensive review.

    Science.gov (United States)

    Araya-Anchetta, Ana; Busch, Joseph D; Scoles, Glen A; Wagner, David M

    2015-01-01

    Population genetic studies provide insights into the basic biology of arthropod disease vectors by estimating dispersal patterns and their potential to spread pathogens. In wingless vectors, such as ticks, gene flow will be defined in large part by the mobility of their hosts. However, tick behaviors and life cycle strategies can limit their dispersal even on highly mobile hosts and lead to an increase in genetic structure. In this review we synthesize the published literature from three decades of tick population genetic studies. Based on studies from 22 tick species (including representatives from Amblyomma, Bothriocroton, Dermacentor, Ixodes, Ornithodoros, and Rhipicephalus), observed levels of population genetic structure in ticks varied from no structure to very high levels. In about half of the species (including representatives from Amblyomma, Bothriocroton, Dermacentor, and Ornithodoros), tick genetic structure appeared to be determined primarily by the movement capacity of hosts, with low gene flow observed in ticks that use smaller bodied less mobile hosts and high gene flow in ticks using highly mobile hosts. In a number of other species (primarily from Ixodes, Ornithodoros, and Rhipicephalus), behavioral limitations to gene flow appeared to result in greater genetic structure than expected based upon host movement capability alone. We also discuss the strengths and limitations of genetic markers and their applicability to ticks and suggest possible analyses when planning population genetic studies for ticks.

  7. Modernization, Population Dispersion, and Papago Genetic Integrity

    Science.gov (United States)

    Smith, David G.

    1972-01-01

    That residents of Papago villages were less closely related in the 19th century than during recent decades is considered in historical and genetic perspectives. A preliminary version of this paper was read at the annual meeting of the American Anthropological Association, New York City, 1971. (FF)

  8. Genetic assessment of captive red panda (Ailurus fulgens) population.

    Science.gov (United States)

    Kumar, Arun; Rai, Upashna; Roka, Bhupen; Jha, Alankar K; Reddy, P Anuradha

    2016-01-01

    Red panda (Ailurus fulgens) is threatened across its range by detrimental human activities and rapid habitat changes necessitating captive breeding programs in various zoos globally to save this flagship species from extinction. One of the ultimate aims of ex situ conservation is reintroduction of endangered animals into their natural habitats while maintaining 90 % of the founder genetic diversity. Advances in molecular genetics and microsatellite genotyping techniques make it possible to accurately estimate genetic diversity of captive animals of unknown ancestry. Here we assess genetic diversity of the red panda population in Padmaja Naidu Himalayan Zoological Park, Darjeeling, which plays a pivotal role in ex situ conservation of red panda in India. We generated microsatellite genotypes of fifteen red pandas with a set of fourteen loci. This population is genetically diverse with 68 % observed heterozygosity (HO) and mean inbreeding (FIS) coefficient of 0.05. However population viability analysis reveals that this population has a very low survival probability (<2 %) and will rapidly loose its genetic diversity to 37 % mainly due to small population size and skewed male-biased sex ratio. Regular supplementation with a pair of adult individuals every five years will increase survival probability and genetic diversity to 99 and 61 % respectively and will also support future harvesting of individuals for reintroduction into the wild and exchange with other zoos.

  9. Genetic diversity and population structure of cucumber (Cucumis sativus L..

    Directory of Open Access Journals (Sweden)

    Jing Lv

    Full Text Available Knowing the extent and structure of genetic variation in germplasm collections is essential for the conservation and utilization of biodiversity in cultivated plants. Cucumber is the fourth most important vegetable crop worldwide and is a model system for other Cucurbitaceae, a family that also includes melon, watermelon, pumpkin and squash. Previous isozyme studies revealed a low genetic diversity in cucumber, but detailed insights into the crop's genetic structure and diversity are largely missing. We have fingerprinted 3,342 accessions from the Chinese, Dutch and U.S. cucumber collections with 23 highly polymorphic Simple Sequence Repeat (SSR markers evenly distributed in the genome. The data reveal three distinct populations, largely corresponding to three geographic regions. Population 1 corresponds to germplasm from China, except for the unique semi-wild landraces found in Xishuangbanna in Southwest China and East Asia; population 2 to Europe, America, and Central and West Asia; and population 3 to India and Xishuangbanna. Admixtures were also detected, reflecting hybridization and migration events between the populations. The genetic background of the Indian germplasm is heterogeneous, indicating that the Indian cucumbers maintain a large proportion of the genetic diversity and that only a small fraction was introduced to other parts of the world. Subsequently, we defined a core collection consisting of 115 accessions and capturing over 77% of the SSR alleles. Insight into the genetic structure of cucumber will help developing appropriate conservation strategies and provides a basis for population-level genome sequencing in cucumber.

  10. Population Genetic Structure of Aedes fluviatilis (Diptera: Culicidae)

    Science.gov (United States)

    Multini, Laura Cristina; Suesdek, Lincoln; Marrelli, Mauro Toledo

    2016-01-01

    Although Aedes fluviatilis is an anthropophilic mosquito found abundantly in urban environments, its biology, epidemiological potential and genetic characteristics are poorly understood. Climate change and urbanization processes that result in environmental modifications benefit certain anthropophilic mosquito species such as Ae. fluviatilis, greatly increasing their abundance in urban areas. To gain a better understanding of whether urbanization processes modulate the genetic structure of this species in the city of São Paulo, we used eight microsatellite loci to genetically characterize Ae. fluviatilis populations collected in nine urban parks in the city of São Paulo. Our results show that there is high gene flow among the populations of this species, heterozygosity deficiency and low genetic structure and that the species may have undergone a recent population expansion. There are two main hypotheses to explain these findings: (i) Ae. fluviatilis populations have undergone a population expansion as a result of urbanization; and (ii) as urbanization of the city of São Paulo occurred recently and was quite intense, the structuring of these populations cannot be observed yet, apart from in the populations of Ibirapuera and Piqueri parks, where the first signs of structuring have appeared. We believe that the expansion found in Ae. fluviatilis populations is probably correlated with the unplanned urbanization of the city of São Paulo, which transformed green areas into urbanized areas, as well as the increasing population density in the city. PMID:27598889

  11. Host genetics and population structure effects on parasitic disease.

    Science.gov (United States)

    Williams-Blangero, Sarah; Criscione, Charles D; VandeBerg, John L; Correa-Oliveira, Rodrigo; Williams, Kimberly D; Subedi, Janardan; Kent, Jack W; Williams, Jeff; Kumar, Satish; Blangero, John

    2012-03-19

    Host genetic factors exert significant influences on differential susceptibility to many infectious diseases. In addition, population structure of both host and parasite may influence disease distribution patterns. In this study, we assess the effects of population structure on infectious disease in two populations in which host genetic factors influencing susceptibility to parasitic disease have been extensively studied. The first population is the Jirel population of eastern Nepal that has been the subject of research on the determinants of differential susceptibility to soil-transmitted helminth infections. The second group is a Brazilian population residing in an area endemic for Trypanosoma cruzi infection that has been assessed for genetic influences on differential disease progression in Chagas disease. For measures of Ascaris worm burden, within-population host genetic effects are generally more important than host population structure factors in determining patterns of infectious disease. No significant influences of population structure on measures associated with progression of cardiac disease in individuals who were seropositive for T. cruzi infection were found.

  12. Molecular Population Genetics of Rice Domestication

    Institute of Scientific and Technical Information of China (English)

    Tian Tang; Suhua Shi

    2007-01-01

    Domestication is a selection process that genetically modifies species to meet human needs. A most intriguing feature of domestication is the extreme phenotypic diversification among breeds. What could be the ultimate source of such genetic variations? Another notable outcome of artificial selection is the reduction in the fitness of domesticated species when they live in the wild without human assistance. The complete sequences of the two subspecies of rice cultivars provide an opportunity to address these questions. Between the two subspecies, we found much higher rates of non-synonymous (N) than synonymous (S) substitutions and the N/S ratios are higher between cultivars than between wild species. Most interestingly, substitutions of highly dissimilar amino acids that are deleterious and uncommon between natural species are disproportionately common between the two subspecies of rice. We suggest strong selection in the absence of effective recombination may be the driving force, which we called the domestication-associated Hill-Robertson effect. These hitchhiking mutations may contribute to some fitness reduction in cultivars. Comparisons of the two genomes also reveal the existence of highly divergent regions in the genomes. Haplotypes in these regions often form highly polymorphic linkage blocks that are much older than speciation between wild species. Genes from such regions could contribute to the differences between indica and japonica and are likely to be involved in the diversifying selection under domestication. Their existence suggests that the amount of genetic variation within the single progenitor species Oryza ruflpogon may be insufficient to account for the variation among rice cultivars, which may come from a more inclusive gene pool comprising most of the A-genome wild species. Genes from the highly polymorphic regions also provide strong support for the independent domestication of the two subspecies. The genomic variation in rice has revealing

  13. The human genetic history of the Americas: the final frontier.

    Science.gov (United States)

    O'Rourke, Dennis H; Raff, Jennifer A

    2010-02-23

    The Americas, the last continents to be entered by modern humans, were colonized during the late Pleistocene via a land bridge across what is now the Bering strait. However, the timing and nature of the initial colonization events remain contentious. The Asian origin of the earliest Americans has been amply established by numerous classical marker studies of the mid-twentieth century. More recently, mtDNA sequences, Y-chromosome and autosomal marker studies have provided a higher level of resolution in confirming the Asian origin of indigenous Americans and provided more precise time estimates for the emergence of Native Americans. But these data raise many additional questions regarding source populations, number and size of colonizing groups and the points of entry to the Americas. Rapidly accumulating molecular data from populations throughout the Americas, increased use of demographic models to test alternative colonization scenarios, and evaluation of the concordance of archaeological, paleoenvironmental and genetic data provide optimism for a fuller understanding of the initial colonization of the Americas.

  14. Toward a Better Understanding of Population Genetics: Pop!World--A Virtual, Inquiry-Based Tool for Teaching Population Genetics

    Science.gov (United States)

    Poulin, Jessica; Ramamurthy, Bina; Dittmar, Katharina

    2013-01-01

    Population genetics is fundamental to understanding evolutionary theory, and is taught in most introductory biology/evolution courses. Many students are unaware that understanding this topic requires pertinent knowledge

  15. Toward a Better Understanding of Population Genetics: Pop!World--A Virtual, Inquiry-Based Tool for Teaching Population Genetics

    Science.gov (United States)

    Poulin, Jessica; Ramamurthy, Bina; Dittmar, Katharina

    2013-01-01

    Population genetics is fundamental to understanding evolutionary theory, and is taught in most introductory biology/evolution courses. Many students are unaware that understanding this topic requires pertinent knowledge

  16. Medical Genetics and the First Studies of the Genetics of Populations in Mexico.

    Science.gov (United States)

    Barahona, Ana

    2016-09-01

    Following World War II (WWII), there was a new emphasis within genetics on studying the genetic composition of populations. This probably had a dual source in the growing strength of evolutionary biology and the new international interest in understanding the effects of radiation on human populations, following the atomic bombings in Japan. These global concerns were shared by Mexican physicians. Indeed, Mexico was one of the leading centers of this trend in human genetics. Three leading players in this story were Mario Salazar Mallén, Adolfo Karl, and Rubén Lisker. Their trajectories and the international networks in human genetics that were established after WWII, paved the way for the establishment of medical and population genetics in Mexico. Salazar Mallén's studies on the distribution and characterization of ABO blood groups in indigenous populations were the starting point while Karl's studies on the distribution of abnormal hemoglobin in Mexican indigenous populations showed the relationships observed in other laboratories at the time. It was Lisker's studies, however, that were instrumental in the development of population genetics in the context of national public policies for extending health care services to the Mexican population. In particular, he conducted studies on Mexican indigenous groups contributing to the knowledge of the biological diversity of human populations according to international trends that focused on the variability of human populations in terms of genetic frequencies. From the start, however, Lisker was as committed to the reconstruction of shared languages and practices as he was to building networks of collaboration in order to guarantee the necessary groundwork for establishing the study of the genetics of human populations in Mexico. This study also allows us to place Mexican science within a global context in which connected narratives describe the interplay between global trends and national contexts. Copyright © 2016 by

  17. The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape.

    Science.gov (United States)

    Dobon, Begoña; Hassan, Hisham Y; Laayouni, Hafid; Luisi, Pierre; Ricaño-Ponce, Isis; Zhernakova, Alexandra; Wijmenga, Cisca; Tahir, Hanan; Comas, David; Netea, Mihai G; Bertranpetit, Jaume

    2015-01-01

    East Africa is a strategic region to study human genetic diversity due to the presence of ethnically, linguistically, and geographically diverse populations. Here, we provide new insight into the genetic history of populations living in the Sudanese region of East Africa by analysing nine ethnic groups belonging to three African linguistic families: Niger-Kordofanian, Nilo-Saharan and Afro-Asiatic. A total of 500 individuals were genotyped for 200,000 single-nucleotide polymorphisms. Principal component analysis, clustering analysis using ADMIXTURE, FST statistics, and the three-population test were used to investigate the underlying genetic structure and ancestry of the different ethno-linguistic groups. Our analyses revealed a genetic component for Sudanese Nilo-Saharan speaking groups (Darfurians and part of Nuba populations) related to Nilotes of South Sudan, but not to other Sudanese populations or other sub-Saharan populations. Populations inhabiting the North of the region showed close genetic affinities with North Africa, with a component that could be remnant of North Africans before the migrations of Arabs from Arabia. In addition, we found very low genetic distances between populations in genes important for anti-malarial and anti-bacterial host defence, suggesting similar selective pressures on these genes and stressing the importance of considering functional pathways to understand the evolutionary history of populations.

  18. Translating Population Difference: The Use and Re-Use of Genetic Ancestry in Brazilian Cancer Genetics.

    Science.gov (United States)

    Gibbon, Sahra

    2016-01-01

    In the past ten years, there has been an expansion of scientific interest in population genetics linked to both understanding histories of human migration and the way that population difference and diversity may account for and/or be implicated in health and disease. In this article, I examine how particular aspects of a globalizing research agenda related to population differences and genetic ancestry are taken up in locally variant ways in the nascent field of Brazilian cancer genetics. Drawing on a broad range of ethnographic data from clinical and nonclinical contexts in the south of Brazil, I examine the ambiguities that attention to genetic ancestry generates, so revealing the disjunctured and diverse ways a global research agenda increasingly orientated to questions of population difference and genetic ancestry is being used and reused.

  19. Genetic variation in natural honeybee populations, Apis mellifera capensis

    Science.gov (United States)

    Hepburn, Randall; Neumann, Peter; Radloff, Sarah E.

    2004-09-01

    Genetic variation in honeybee, Apis mellifera, populations can be considerably influenced by breeding and commercial introductions, especially in areas with abundant beekeeping. However, in southern Africa apiculture is based on the capture of wild swarms, and queen rearing is virtually absent. Moreover, the introduction of European subspecies constantly failed in the Cape region. We therefore hypothesize a low human impact on genetic variation in populations of Cape honeybees, Apis mellifera capensis. A novel solution to studying genetic variation in honeybee populations based on thelytokous worker reproduction is applied to test this hypothesis. Environmental effects on metrical morphological characters of the phenotype are separated to obtain a genetic residual component. The genetic residuals are then re-calculated as coefficients of genetic variation. Characters measured included hair length on the abdomen, width and length of wax plate, and three wing angles. The data show for the first time that genetic variation in Cape honeybee populations is independent of beekeeping density and probably reflects naturally occurring processes such as gene flow due to topographic and climatic variation on a microscale.

  20. Microsatellite analysis of genetic diversity and population structure of Arabian horse populations.

    Science.gov (United States)

    Khanshour, Anas; Conant, Eleanore; Juras, Rytis; Cothran, Ernest Gus

    2013-01-01

    The Arabian horse ignites imagination throughout the world. Populations of this breed exist in many countries, and recent genetic work has examined the diversity and ancestry of a few of these populations in isolation. Here, we explore 7 different populations of Arabians represented by 682 horses. Three of these are Middle Eastern populations from near the historical origin of the breed, including Syrian, Persian, and Saudi Arabian. The remaining Western populations are found in Europe (the Shagya Arabian and Polish Arabian) and in America (American Arabian). Analysis of genetic structure was carried out using 15 microsatellite loci. Genetic distances, analysis of molecular variance, factorial correspondence analysis, and a Bayesian method were applied. The results consistently show higher level of diversity within the Middle Eastern populations than the Western populations. The Western Arabian populations were the main source among population variation. Genetic differentiation was not strong among all Middle Eastern populations, but all American Arabians showed differentiation from Middle Eastern populations and were somewhat uniform among themselves. Here, we explore the diversities of many different populations of Arabian horses and find that populations not from the Middle East have noticeably lower levels of diversity, which may adversely affect the health of these populations.

  1. Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons.

    Science.gov (United States)

    Meng, Hao-Tian; Shen, Chun-Mei; Zhang, Yu-Dang; Dong, Qian; Guo, Yu-Xin; Yang, Guang; Yan, Jiang-Wei; Liu, Yao-Shun; Mei, Ting; Shi, Jian-Feng; Zhu, Bo-Feng

    2017-09-01

    The Xibe population is one of China's officially recognised populations and is now distributed separately from west to east in the northern part of China. X-chromosomal short tandem repeats have a special inheritance pattern, and could be used as complements in forensic application, especially for complex or deficiency cases. This study obtained the allelic and haplotypic frequencies of 19 X-STR loci in the Xibe population from Xinjiang Uygur Autonomous Region, China, and studied the genetic differentiations between the Xibe and other populations. The combined power of discrimination in females and males and mean exclusion chances in deficiency cases, normal trios and duo cases was at least 0.999 999 994. In the haplotypic study, the Xibe population showed a more similar pattern of haplotype distribution with Asian populations than populations from other continents, while allelic study also indicated a closer relationship between the Xibe and Asian populations. The 19 X-STR loci would be useful in forensic application in the studied population. The Xibe population showed a closer genetic relationship with Asian populations in the study, and more population data would be necessary for more detailed genetic relationship studies.

  2. Genetic analysis of population differentiation and adaptation in Leuciscus waleckii.

    Science.gov (United States)

    Chang, Yumei; Tang, Ran; Sun, Xiaowen; Liang, Liqun; Chen, Jinping; Huang, Jinfeng; Dou, Xinjie; Tao, Ran

    2013-12-01

    Demographic events and natural selection both influence animal phenotypic and genetic variation; exploring the effects of demography and selection on population divergence is of great significance in evolutionary biology. To uncover the causes behind the patterns of genetic differentiation and adaptation among six populations of Leuciscus waleckii from Dali Basin (two populations, alkaline vs. freshwater) and Amur Basin (four populations, freshwater rivers vs. alkaline lake), a set of 21 unlinked polymorphic microsatellite markers and two mitochondrial DNA sequences (Cytb and D-loop) were applied to examine whether populations from different environments or habitats have distinct genetic differentiation and whether alkalinity is the major factor that caused population divergence. Bayesian analysis and principal component analysis as well as haplotype network analysis showed that these populations are primarily divided into two groups, which are congruent with geographic separation but not inconsistent with the habitat environment (alkalinity). Using three different approaches, outlier detection indicated that one locus, HLJYL017, may be under directional selection and involved in local adaptation processes. Overall, this study suggested that demographic events and selection of local environmental conditions including of alkalinity are jointly responsible for population divergence. These findings constitute an important step towards the understanding of the genetic basis of differentiation and adaptation, as well as towards the conservation of L. waleckii.

  3. Genetic distance and species formation in evolving populations.

    Science.gov (United States)

    Higgs, P G; Derrida, B

    1992-11-01

    We compare the behavior of the genetic distance between individuals in evolving populations for three stochastic models. In the first model reproduction is asexual and the distribution of genetic distances reflects the genealogical tree of the population. This distribution fluctuates greatly in time, even for very large populations. In the second model reproduction is sexual with random mating allowed between any pair of individuals. In this case, the population becomes homogeneous and the genetic distance between pairs of individuals has small fluctuations which vanish in the limit of an infinitely large population. In the third model reproduction is still sexual but instead of random mating, mating only occurs between individuals which are genetically similar to each other. In that case, the population splits spontaneously into species which are in reproductive isolation from one another and one observes a steady state with a continual appearance and extinction of species in the population. We discuss this model in relation to the biological theory of speciation and isolating mechanisms. We also point out similarities between these three models of evolving populations and the theory of disordered systems in physics.

  4. Population structure and genetic diversity of Sudanese native chickens

    African Journals Online (AJOL)

    User

    2013-11-06

    Nov 6, 2013 ... origin of breeding populations, molecular marker informa-. *Corresponding .... on the phenotypic characteristics of each local breed (Desai, 1962). ..... Development of a genetic map of the chicken with markers of ... variation and population structure of Italian native sheep breeds ... evolutionary studies. Mol.

  5. Population genetics of Wolbachia-infected, parthenogenetic and uninfected, sexual populations of Tetrastichus coeruleus (Hymenoptera: Eulophidae).

    Science.gov (United States)

    Reumer, Barbara M; van Alphen, Jacques J M; Kraaijeveld, Ken

    2013-09-01

    Wolbachia are endosymbiotic bacteria known to manipulate the reproduction of their hosts. These manipulations are expected to have consequences on the population genetics of the host, such as heterozygosity levels, genetic diversity and gene flow. The parasitoid wasp Tetrastichus coeruleus has populations that are infected with parthenogenesis-inducing Wolbachia and populations that are not infected. We studied the population genetics of T. coeruleus between and within Wolbachia-infected and uninfected populations, using nuclear microsatellites and mitochondrial DNA. We expected reduced genetic diversity in both DNA types in infected populations. However, migration and gene flow could introduce new DNA variants into populations. We therefore paid special attention to individuals with unexpected (genetic) characteristics. Based on nuclear and mitochondrial DNA, two genetic clusters were evident: a thelytokous cluster containing all Wolbachia-infected, parthenogenetic populations and an arrhenotokous cluster containing all uninfected, sexual populations. Nuclear and mitochondrial DNA did not exhibit concordant patterns of variation, although there was reduced genetic diversity in infected populations for both DNA types. Within the thelytokous cluster, there was nuclear DNA variation, but no mitochondrial DNA variation. This nuclear DNA variation may be explained by occasional sex between infected females and males, by horizontal transmission of Wolbachia, and/or by novel mutations. Several females from thelytokous populations were uninfected and/or heterozygous for microsatellite loci. These unexpected characteristics may be explained by migration, by inefficient transmission of Wolbachia, by horizontal transmission of Wolbachia, and/or by novel mutations. However, migration has not prevented the build-up of considerable genetic differentiation between thelytokous and arrhenotokous populations.

  6. Population genetic structure of Venezuelan chiropterophilous columnar cacti (Cactaceae).

    Science.gov (United States)

    Nassar, Jafet M; Hamrick, J L; Fleming, Theodore H

    2003-11-01

    We conducted allozyme surveys of three Venezuelan self-incompatible chiropterophilous columnar cacti: two diploid species, Stenocereus griseus and Cereus repandus, and one tetraploid, Pilosocereus lanuginosus. The three cacti are pollinated by bats, and both bats and birds disperse seeds. Population sampling comprised two spatial scales: all Venezuelan arid zones (macrogeographic) and two arid regions in northwestern Venezuela (regional). Ten to 15 populations and 17-23 loci were analyzed per species. Estimates of genetic diversity were compared with those of other allozyme surveys in the Cactaceae to examine how bat-mediated gene dispersal affects the population genetic attributes of the three cacti. Genetic diversity was high for both diploid (P(s) = 94.1-100, P(p) = 56.7-72.3, H(s) = 0.182-0.242, H(p) = 0.161-0.205) and tetraploid (P(s) = 93.1, P(p) = 76.1, H(s) = 0.274, H(p) = 0.253) species. Within-population heterozygote deficit was detected in the three cacti at macrogeographic (F(IS) = 0.145-0.182) and regional (F(IS) = 0.057-0.174) levels. Low genetic differentiation was detected at both macrogeographic (G(ST) = 0.043-0.126) and regional (G(ST) = 0.009-0.061) levels for the three species, suggesting substantial gene flow among populations. Gene exchange among populations seems to be regulated by distance among populations. Our results support the hypothesis that bat-mediated gene dispersal confers high levels of genetic exchange among populations of the three columnar cacti, a process that enhances levels of genetic diversity within their populations.

  7. Dynamic Change of Genetic Diversity in Conserved Populations with Different Initial Genetic Architectures

    Institute of Scientific and Technical Information of China (English)

    LU Yun-feng; LI Hong-wei; WU Ke-liang; WU Chang-xin

    2013-01-01

    Maintenance and management of genetic diversity of farm animal genetic resources (AnGR) is very important for biological, socioeconomical and cultural significance. The core concern of conservation for farm AnGR is the retention of genetic diversity of conserved populations in a long-term perspective. However, numerous factors may affect evolution of genetic diversity of a conserved population. Among those factors, the genetic architecture of conserved populations is little considered in current conservation strategies. In this study, we investigated the dynamic changes of genetic diversity of conserved populations with two scenarios on initial genetic architectures by computer simulation in which thirty polymorphic microsatellite loci were chosen to represent genetic architecture of the populations with observed heterozygosity (Ho) and expected heterozygosity (He), observed and mean effective number of alleles (Ao and Ae), number of polymorphic loci (NP) and the percentage of polymorphic loci (PP), number of rare alleles (RA) and number of non-rich polymorphic loci (NRP) as the estimates of genetic diversity. The two scenarios on genetic architecture were taken into account, namely, one conserved population with same allele frequency (AS) and another one with actual allele frequency (AA). The results showed that the magnitude of loss of genetic diversity is associated with genetic architecture of initial conserved population, the amplitude of genetic diversity decline in the context AS was more narrow extent than those in context AA, the ranges of decline of Ho and Ao were about 4 and 2 times in AA compared with that in AS, respectively, the occurrence of first monomorphic locus and the time of change of measure NP in scenario AA is 20 generations and 23 generations earlier than that in scenario AS, respectively. Additionally, we found that NRP, a novel measure proposed by our research group, was a proper estimate for monitoring the evolution of genetic diversity

  8. From hybrids to hermaphrodites in population genetics

    OpenAIRE

    Robert Verity; Jeannine Marquardt; Andrea Hatlen; Jasmin Zohren

    2013-01-01

    Shortly before Christmas 2012, the 46th PopGroup (Popu­ lation Genetics Group) meeting was held at Glasgow University, UK. Over 180 scientists attended from 19 different countries, with speakers from diverse research areas and ranging from PhD students to retired profes­ sors. Some talks dealt with the conservation of exotic species on remote islands, while others took a more theo­ retical approach. Almost all made use of, or anticipated, the volume and ever­reducing cost of d...

  9. Olhares sociológicos sobre a ciência no século vinte: mudanças e continuidades Sociological looks on Science in the twentieth century: changes and continuities

    Directory of Open Access Journals (Sweden)

    Marcelo Fetz

    2011-08-01

    Full Text Available O artigo examina, em dois momentos distintos, as principais abordagens sociológicas sobre a ciência no século vinte: a Sociologia do Conhecimento, a Sociologia da Ciência e a Sociologia do Conhecimento Científico. No primeiro tópico são recapitulados os argumentos sociológicos de Karl Mannheim e de Robert King Merton. Defende-se a interpretação de que a obra de Mannheim seja reconhecida enquanto pressuposto epistemológico para o desenvolvimento da Sociologia da Ciência de Merton. Adaptada por Merton, a metateoria sociológica de Mannheim surge através de uma abordagem estrutural funcionalista associada a uma teoria de médio alcance. No segundo momento, são retomados os argumentos de Thomas Kuhn para, logo após, ser analisada a Sociologia do Conhecimento Científico enquanto apreciação construtiva da tradição de pensamento mertoniana. O estudo dos princípios lógicos da Sociologia do Conhecimento Científico de David Bloor e a investigação acerca da tradição de pensamento iniciada na Universidade de Edimburgo, na Escócia, foram o foco elementar dessa etapa do artigo. Finalmente, as principais características de cada uma das tradições são ressaltadas, buscando-se por mudanças e continuidades que viabilizaram o desenvolvimento da abordagem sociológica sobre a atividade científica desde sua gênese clássica até os estudos contemporâneos.The article examines, in two different moments, the major sociological approaches to science in the twentieth century: the Sociology of Knowledge, the Sociology of Science and the Sociology of Scientific Knowledge. In the first topic, Karl Mannheim's and Robert King Merton's sociological arguments are summarized. We support that the interpretation of Mannheim's work must be recognized as an epistemological prerequisite to the development of Merton's Sociology of Science. Adapted by Merton, Mannheim's sociological metatheory appears in Merton through a functional structuralism

  10. Quantifying population genetic differentiation from next-generation sequencing data

    DEFF Research Database (Denmark)

    Fumagalli, Matteo; Garrett Vieira, Filipe Jorge; Korneliussen, Thorfinn Sand

    2013-01-01

    Over the last few years, new high-throughput DNA sequencing technologies have dramatically increased speed and reduced sequencing costs. However, the use of these sequencing technologies is often challenged by errors and biases associated with the bioinformatical methods used for analyzing the data...... method for quantifying population genetic differentiation from next-generation sequencing data. In addition, we present a strategy to investigate population structure via Principal Components Analysis. Through extensive simulations, we compare the new method herein proposed to approaches based...... individuals, suggesting that employing this new method is useful for investigating the genetic relationships of populations sampled at low coverage....

  11. Population genetics in minority children with type 2 diabetes mellitus.

    Science.gov (United States)

    Wallerstein, Robert

    2002-04-01

    Non-insulin dependent (type 2) diabetes mellitus (DM) is a rapidly emerging health threat in minority populations in the United States, with the African-American, Hispanic, and Native American populations at greatest risk. Clearly, environmental factors play a role in this disorder, but the ethnic predilection suggests a significant genetic component. Type 2 DM is a condition not well understood on a genetic basis. Familial clustering and ethnic variation have been documented. The populations of Africans living in diverse environments provide a unique opportunity to study type 2 DM as the mechanism is becoming more clear.

  12. Stellar Population Analysis of Galaxies based on Genetic Algorithms

    Institute of Scientific and Technical Information of China (English)

    Abdel-Fattah Attia; H.A.Ismail; I.M.Selim; A.M.Osman; I.A.Isaa; M.A.Marie; A.A.Shaker

    2005-01-01

    We present a new method for determining the age and relative contribution of different stellar populations in galaxies based on the genetic algorithm.We apply this method to the barred spiral galaxy NGC 3384, using CCD images in U, B, V, R and I bands. This analysis indicates that the galaxy NGC 3384 is mainly inhabited by old stellar population (age > 109 yr). Some problems were encountered when numerical simulations are used for determining the contribution of different stellar populations in the integrated color of a galaxy. The results show that the proposed genetic algorithm can search efficiently through the very large space of the possible ages.

  13. The Etruscans: a population-genetic study

    DEFF Research Database (Denmark)

    Vernesi, Cristiano; Caramelli, David; Dupanloup, Isabelle;

    2004-01-01

    The origins of the Etruscans, a non-Indo-European population of preclassical Italy, are unclear. There is broad agreement that their culture developed locally, but the Etruscans' evolutionary and migrational relationships are largely unknown. In this study, we determined mitochondrial DNA sequences...

  14. Best practices for population genetic analyses

    Science.gov (United States)

    This review will attempt to address many of these practical questions that are often not readily answered from reading books or reviews on the topic, but emerge from discussions with colleagues and from practical experience. A further complication for microbial or pathogen populations is the frequen...

  15. Population genetic structure in natural and reintroduced beaver (Castor fiber populations in Central Europe

    Directory of Open Access Journals (Sweden)

    Kautenburger, R.

    2008-12-01

    Full Text Available Castor fiber Linnaeus, 1758 is the only indigenous species of the genus Castor in Europe and Asia. Due to extensive hunting until the beginning of the 20th century, the distribution of the formerly widespread Eurasian beaver was dramatically reduced. Only a few populations remained and these were in isolated locations, such as the region of the German Elbe River. The loss of genetic diversity in small or captive populations throughgenetic drift and inbreeding is a severe conservation problem. However, the reintroduction of beaver populations from several regions in Europe has shown high viability and populations today are growing fast. In the present study we analysed the population genetic structure of a natural and two reintroduced beaver populations in Germany and Austria. Furthermore, we studied the genetic differentiation between two beaver species, C. fiber and the American beaver (C. canadensis, using RAPD (Random Amplified Polymorphic DNA as a genetic marker. The reintroduced beaver populations of different origins and the autochthonous population of the Elbe River showed a similar low genetic heterogeneity. There was an overall high genetic similarity in the species C. fiber, and no evidence was found for a clear subspecific structure in the populations studied.

  16. Iberia: population genetics, anthropology, and linguistics.

    Science.gov (United States)

    Arnaiz-Villena, A; Martínez-Laso, J; Alonso-García, J

    1999-10-01

    Basques, Portuguese, Spaniards, and Algerians have been studied for HLA and mitochondrial DNA markers, and the data analysis suggests that pre-Neolithic gene flow into Iberia came from ancient white North Africans (Hamites). The Basque language has also been used to translate the Iberian-Tartesian language and also Etruscan and Minoan Linear A. Physical anthropometry of Iberian Mesolithic and Neolithic skeletons does not support the demic replacement in Iberia of preexisting Mesolithic people by Neolithic people bearing new farming technologies from Europe and the Middle East. Also, the presence of cardial impressed pottery in western Mediterranean Europe and across the Maghreb (North Africa) coasts at the beginning of the Neolithic provides good evidence of pre-Neolithic circum-Mediterranean contacts by sea. In addition, pre-dynastic Egyptian El-Badari culture (4,500 years ago) is similar to southern Iberian Neolithic settlements with regard to pottery and animal domestication. Taking the genetic, linguistic, anthropological, and archeological evidence together with the documented Saharan area desiccation starting about 10,000 years ago, we believe that it is possible that a genetic and cultural pre-Neolithic flow coming from southern Mediterranean coasts existed toward northern Mediterranean areas, including at least Iberia and some Mediterranean islands. This model would substitute for the demic diffusion model put forward to explain Neolithic innovations in Western Europe.

  17. O Jequitinhonha dos viajantes, séculos XIX e XX: olhares diversos sobre as relações sociedade - natureza no nordeste mineiro The voyagers' Jequitinhonha, Nineteenth and Twentieth centuries: different views over the society - nature relations in northeast Minas Gerais

    Directory of Open Access Journals (Sweden)

    Marcos Lobato Martins

    2008-12-01

    Full Text Available Este trabalho analisa as mudanças ambientais no Médio Jequitinhonha entre o início do século XIX e o início do XX, através da releitura de relatos de viajantes e textos de memorialistas. São indicadas as principais formas de degradação ambiental presentes na região e avaliados os seus impactos sobre as caatingas e as matas virgens. Conclui-se que: a houve aumento expressivo da velocidade de alteração das paisagens regionais na primeira metade do século XX e; b essa alteração fortaleceu a tendência de pecuarização na economia do Médio Jequitinhonha.This paper analyzes the environmental changes in the Middle Jequitinhonha between the nineteenth and twentieth centuries beginnings, through the reading of the memoirialists and voyagers reports. The major environmental degradating actions that take place in the region are indicated and its impacts over the caatingas and forests are evaluated. It concludes: a an expressive increase in the velocity of the regional landscapes change in the first half of twentieth century; b and this change annealed the tendency of cattle's predominance in Middle Jequitinhonha economy.

  18. Population genetic structure of traditional populations in the Peruvian Central Andes and implications for South American population history.

    Science.gov (United States)

    Cabana, Graciela S; Lewis, Cecil M; Tito, Raúl Y; Covey, R Alan; Cáceres, Angela M; Cruz, Augusto F De La; Durand, Diana; Housman, Genevieve; Hulsey, Brannon I; Iannacone, Gian Carlo; López, Paul W; Martínez, Rolando; Medina, Ángel; Dávila, Olimpio Ortega; Pinto, Karla Paloma Osorio; Santillán, Susan I Polo; Domínguez, Percy Rojas; Rubel, Meagan; Smith, Heather F; Smith, Silvia E; Massa, Verónica Rubín de Celis; Lizárraga, Beatriz; Stone, Anne C

    2014-01-01

    Molecular-based characterizations of Andean peoples are traditionally conducted in the service of elucidating continent-level evolutionary processes in South America. Consequently, genetic variation among "western" Andean populations is often represented in relation to variation among "eastern" Amazon and Orinoco River Basin populations. This west-east contrast in patterns of population genetic variation is typically attributed to large-scale phenomena, such as dual founder colonization events or differing long-term microevolutionary histories. However, alternative explanations that consider the nature and causes of population genetic diversity within the Andean region remain underexplored. Here we examine population genetic diversity in the Peruvian Central Andes using data from the mtDNA first hypervariable region and Y-chromosome short tandem repeats among 17 newly sampled populations and 15 published samples. Using this geographically comprehensive data set, we first reassessed the currently accepted pattern of western versus eastern population genetic structure, which our results ultimately reject: mtDNA population diversities were lower, rather than higher, within Andean versus eastern populations, and only highland Y-chromosomes exhibited significantly higher within-population diversities compared with eastern groups. Multiple populations, including several highland samples, exhibited low genetic diversities for both genetic systems. Second, we explored whether the implementation of Inca state and Spanish colonial policies starting at about ad 1400 could have substantially restructured population genetic variation and consequently constitute a primary explanation for the extant pattern of population diversity in the Peruvian Central Andes. Our results suggest that Peruvian Central Andean population structure cannot be parsimoniously explained as the sole outcome of combined Inca and Spanish policies on the region's population demography: highland populations

  19. The Genetic Theory of Infectious Diseases: A Brief History and Selected Illustrations

    Science.gov (United States)

    Casanova, Jean-Laurent; Abel, Laurent

    2016-01-01

    Until the mid-nineteenth century, life expectancy at birth averaged 20 years worldwide, owing mostly to childhood fevers. The germ theory of diseases then gradually overcame the belief that diseases were intrinsic. However, around the turn of the twentieth century, asymptomatic infection was discovered to be much more common than clinical disease. Paradoxically, this observation barely challenged the newly developed notion that infectious diseases were fundamentally extrinsic. Moreover, interindividual variability in the course of infection was typically explained by the emerging immunological (or somatic) theory of infectious diseases, best illustrated by the impact of vaccination. This powerful explanation is, however, best applicable to reactivation and secondary infections, particularly in adults; it can less easily account for interindividual variability in the course of primary infection during childhood. Population and clinical geneticists soon proposed a complementary hypothesis, a germline genetic theory of infectious diseases. Over the past century, this idea has gained some support, particularly among clinicians and geneticists, but has also encountered resistance, particularly among microbiologists and immunologists. We present here the genetic theory of infectious diseases and briefly discuss its history and the challenges encountered during its emergence in the context of the apparently competing but actually complementary microbiological and immunological theories. We also illustrate its recent achievements by highlighting inborn errors of immunity underlying eight life-threatening infectious diseases of children and young adults. Finally, we consider the far-reaching biological and clinical implications of the ongoing human genetic dissection of severe infectious diseases. PMID:23724903

  20. The genetic theory of infectious diseases: a brief history and selected illustrations.

    Science.gov (United States)

    Casanova, Jean-Laurent; Abel, Laurent

    2013-01-01

    Until the mid-nineteenth century, life expectancy at birth averaged 20 years worldwide, owing mostly to childhood fevers. The germ theory of diseases then gradually overcame the belief that diseases were intrinsic. However, around the turn of the twentieth century, asymptomatic infection was discovered to be much more common than clinical disease. Paradoxically, this observation barely challenged the newly developed notion that infectious diseases were fundamentally extrinsic. Moreover, interindividual variability in the course of infection was typically explained by the emerging immunological (or somatic) theory of infectious diseases, best illustrated by the impact of vaccination. This powerful explanation is, however, best applicable to reactivation and secondary infections, particularly in adults; it can less easily account for interindividual variability in the course of primary infection during childhood. Population and clinical geneticists soon proposed a complementary hypothesis, a germline genetic theory of infectious diseases. Over the past century, this idea has gained some support, particularly among clinicians and geneticists, but has also encountered resistance, particularly among microbiologists and immunologists. We present here the genetic theory of infectious diseases and briefly discuss its history and the challenges encountered during its emergence in the context of the apparently competing but actually complementary microbiological and immunological theories. We also illustrate its recent achievements by highlighting inborn errors of immunity underlying eight life-threatening infectious diseases of children and young adults. Finally, we consider the far-reaching biological and clinical implications of the ongoing human genetic dissection of severe infectious diseases.

  1. Genetic resources of teak (Tectona grandis Linn. f.)—strong genetic structure among natural populations

    DEFF Research Database (Denmark)

    Hansen, Ole Kim; Changtragoon, Suchitra; Ponoy, Bundit;

    2015-01-01

    Twenty-nine provenances of teak (Tectona grandis Linn. f.) representing the full natural distribution range of the species were genotyped with microsatellite DNA markers to analyse genetic diversity and population genetic structure. Provenances originating from the semi-moist east coast of India...... had the highest genetic diversity while provenances from Laos showed the lowest. In the eastern part of the natural distribution area, comprising Myanmar, Thailand and Laos, there was a strong clinal decrease in genetic diversity the further east the provenance was located. Overall, the pattern...... of the findings for conservation and use of genetic resources of the species are discussed....

  2. Genetic mixture of multiple source populations accelerates invasive range expansion.

    Science.gov (United States)

    Wagner, Natalie K; Ochocki, Brad M; Crawford, Kerri M; Compagnoni, Aldo; Miller, Tom E X

    2017-01-01

    A wealth of population genetic studies have documented that many successful biological invasions stem from multiple introductions from genetically distinct source populations. Yet, mechanistic understanding of whether and how genetic mixture promotes invasiveness has lagged behind documentation that such mixture commonly occurs. We conducted a laboratory experiment to test the influence of genetic mixture on the velocity of invasive range expansion. The mechanistic basis for effects of genetic mixture could include evolutionary responses (mixed invasions may harbour greater genetic diversity and thus elevated evolutionary potential) and/or fitness advantages of between-population mating (heterosis). If driven by evolution, positive effects of source population mixture should increase through time, as selection sculpts genetic variation. If driven by heterosis, effects of mixture should peak following first reproductive contact and then dissipate. Using a laboratory model system (beetles spreading through artificial landscapes), we quantified the velocity of range expansion for invasions initiated with one, two, four or six genetic sources over six generations. Our experiment was designed to test predictions corresponding to the evolutionary and heterosis mechanisms, asking whether any effects of genetic mixture occurred in early or later generations of range expansion. We also quantified demography and dispersal for each experimental treatment, since any effects of mixture should be manifest in one or both of these traits. Over six generations, invasions with any amount of genetic mixture (two, four and six sources) spread farther than single-source invasions. Our data suggest that heterosis provided a 'catapult effect', leaving a lasting signature on range expansion even though the benefits of outcrossing were transient. Individual-level trait data indicated that genetic mixture had positive effects on local demography (reduced extinction risk and enhanced

  3. Genetic diversity in Chilean populations of rainbow trout, Oncorhynchus mykiss

    Directory of Open Access Journals (Sweden)

    Claudia B Cárcamo

    2015-03-01

    Full Text Available The rainbow trout Oncorhynchus mykiss, was first introduced in Chile between 1905 and 1920 and is currently widely distributed in Chile from Antofagasta (23°S to Patagonia (55°S. The broad range of the geographic and climatic distributions of this species in Chile offers a unique opportunity to study the effect of naturalization of an introduced species on its genetic variability. It is of particular importance to observe the genetic variability of populations in the northern range of this species distribution, in a transition zone where a Mediterranean-type climate changes to an arid climate. The present study analyzed allozymic variability and distribution within and between populations of O. mykiss from the river basins of Elqui and Limari rivers, and six culture strains, using starch-gel protein electrophoresis. Populations were found to be in Hardy-Weinberg equilibrium and the average values of He (0.045, polymorphism (13.9% and allele per locus (1.19 are similar to rainbow trout in its native distributional range. About 77.8% of the genetic variability was within population, similar to the variability reported for wild populations in the northern hemisphere. However, a marked genetic differentiation between wild populations was also found. This is likely to be the consequence of initial founder effects followed by subsequent introgression of resident populations caused by reseeding with trout of different origins in both basins.

  4. Genetic structure in dwarf bamboo (Bashania fangiana clonal populations with different genet ages.

    Directory of Open Access Journals (Sweden)

    Qing-qing Ma

    Full Text Available Amplified fragment length polymorphism (AFLP fingerprints were used to reveal genotypic diversity of dwarf bamboo (Bashania fangiana clonal populations with two different genet ages (≤30 years versus >70 years at Wolong National Natural Reserve, Sichuan province, China. We generated AFLP fingerprints for 96 leaf samples, collected at 30 m intervals in the two populations, using ten selective primer pairs. A total of 92 genotypes were identified from the both populations. The mean proportion of distinguishable genotypes (G/N was 0.9583 (0.9375 to 0.9792 and Simpson's index of diversity (D was 0.9982 (0.9973 to 0.9991. So, two B. fangiana populations were multiclonal and highly diverse. The largest single clone may occur over a distance of about 30 m. Our results demonstrated that the genotypic diversity and genet density of B. fangiana clonal population did not change significantly (47 versus 45 with genet aging and low partitioned genetic differentiation was between the two populations (Gst = 0.0571. The analysis of molecular variance consistently showed that a large proportion of the genetic variation (87.79% existed among the individuals within populations, whereas only 12.21% were found among populations. In addition, the high level of genotypic diversity in the two populations implies that the further works were needed to investigate the reasons for the poor seed set in B. fangiana after flowering.

  5. Genetic diversity among ancient Nordic populations.

    Science.gov (United States)

    Melchior, Linea; Lynnerup, Niels; Siegismund, Hans R; Kivisild, Toomas; Dissing, Jørgen

    2010-01-01

    Using established criteria for work with fossil DNA we have analysed mitochondrial DNA from 92 individuals from 18 locations in Denmark ranging in time from the Mesolithic to the Medieval Age. Unequivocal assignment of mtDNA haplotypes was possible for 56 of the ancient individuals; however, the success rate varied substantially between sites; the highest rates were obtained with untouched, freshly excavated material, whereas heavy handling, archeological preservation and storage for many years influenced the ability to obtain authentic endogenic DNA. While the nucleotide diversity at two locations was similar to that among extant Danes, the diversity at four sites was considerably higher. This supports previous observations for ancient Britons. The overall occurrence of haplogroups did not deviate from extant Scandinavians, however, haplogroup I was significantly more frequent among the ancient Danes (average 13%) than among extant Danes and Scandinavians (approximately 2.5%) as well as among other ancient population samples reported. Haplogroup I could therefore have been an ancient Southern Scandinavian type "diluted" by later immigration events. Interestingly, the two Neolithic samples (4,200 YBP, Bell Beaker culture) that were typed were haplogroup U4 and U5a, respectively, and the single Bronze Age sample (3,300-3,500 YBP) was haplogroup U4. These two haplogroups have been associated with the Mesolithic populations of Central and Northern Europe. Therefore, at least for Southern Scandinavia, our findings do not support a possible replacement of a haplogroup U dominated hunter-gatherer population by a more haplogroup diverse Neolithic Culture.

  6. An integrated approach to historical population assessment of the great whales: case of the New Zealand southern right whale.

    Science.gov (United States)

    Jackson, Jennifer A; Carroll, Emma L; Smith, Tim D; Zerbini, Alexandre N; Patenaude, Nathalie J; Baker, C Scott

    2016-03-01

    Accurate estimation of historical abundance provides an essential baseline for judging the recovery of the great whales. This is particularly challenging for whales hunted prior to twentieth century modern whaling, as population-level catch records are often incomplete. Assessments of whale recovery using pre-modern exploitation indices are therefore rare, despite the intensive, global nature of nineteenth century whaling. Right whales (Eubalaena spp.) were particularly exploited: slow swimmers with strong fidelity to sheltered calving bays, the species made predictable and easy targets. Here, we present the first integrated population-level assessment of the whaling impact and pre-exploitation abundance of a right whale, the New Zealand southern right whale (E. australis). In this assessment, we use a Bayesian population dynamics model integrating multiple data sources: nineteenth century catches, genetic constraints on bottleneck size and individual sightings histories informing abundance and trend. Different catch allocation scenarios are explored to account for uncertainty in the population's offshore distribution. From a pre-exploitation abundance of 28 800-47 100 whales, nineteenth century hunting reduced the population to approximately 30-40 mature females between 1914 and 1926. Today, it stands at less than 12% of pre-exploitation abundance. Despite the challenges of reconstructing historical catches and population boundaries, conservation efforts of historically exploited species benefit from targets for ecological restoration.

  7. Genetic structure and phylogeography of European catfish (Silurus glanis) populations.

    Science.gov (United States)

    Triantafyllidis, A; Krieg, F; Cottin, C; Abatzopoulos, T J; Triantaphyllidis, C; Guyomard, R

    2002-06-01

    The genetic structure of Silurus glanis (Europe's largest freshwater fish species) across most of its natural distribution was investigated using 10 microsatellite loci. The revealed levels of genetic diversity were much higher than previous allozyme and restriction fragment length polymorphism mitochondrial DNA analyses had shown; relative levels of variability among populations were however, in good agreement with the previous studies. Populations from large basins (Volga and Danube rivers) were the most polymorphic, while samples from the smaller Greek rivers, which are more prone to genetic bottleneck, exhibited the lowest levels of genetic diversity. Microsatellite multilocus genotyping permitted the assignment of individual fish to their population of origin with a score as high as 98.3%. Despite the great genetic differentiation of S. glanis populations, no consistent pattern of geographical structuring was revealed, in contrast to previous studies of European freshwater fish species. A model of isolation by distance seems more probable and a hypothesis of recent dispersion from only one glacial refugium is proposed. The discovery of the highest levels of microsatellite and mitochondrial diversity in the Volga sample and the presence of river connections, during the Pleistocene, between this area and all major areas of the present catfish distribution, place this refugium around the Ponto-Caspian region. Combining these data with those from previous studies, a number of markers are now available to monitor wild and hatchery populations even at the individual level.

  8. Population status and population genetics of northern leopard frogs in Arizona

    Science.gov (United States)

    Theimer, Tad C.; Drost, Charles A.; O'Donnell, Ryan P.; Mock, Karen E.

    2011-01-01

    Increasing isolation of populations by habitat fragmentation threatens the persistence of many species, both from stochastic loss of small isolated populations, and from inbreeding effects in populations that have become genetically isolated. In the southwestern United States, amphibian habitat is naturally patchy in occurrence because of the prevailing aridity of the region. Streams, rivers, and other wetlands are important both as habitat and as corridors that connect populations. However, populations of some species have become more fragmented and isolated by habitat degradation and loss. Northern leopard frogs (Rana pipiens) have experienced serious declines in the Southwest. We conducted an extensive survey across the known range of northern leopard frogs in Arizona to determine the current distribution and abundance of the species. From a range that once spanned much of the northern and central part of the State, northern leopard frogs have been reduced to three or four widely separated populations, near Lyman Lake in east-central Arizona, in the Stoneman Lake area south of Flagstaff, along Truxton Wash near Peach Springs, and a population of uncertain extent on Navajo Nation lands. The Lyman Lake and Truxton Wash populations are small and extremely isolated. The Stoneman Lake population, however, is an extensive metapopulation spread across several stream drainages, including numerous ponds, wetlands, and artificial tanks. This is the only population in Arizona that is increasing in extent and numbers, but there is concern about the apparent introduction of nonnative genetic stock from eastern North America into this area. We analyzed genetic diversity within and genetic divergence among populations of northern leopard frogs, across both extant and recently extirpated populations in Arizona. We also analyzed mitochondrial DNA to place these populations into a larger phylogenetic framework and to determine whether any populations contained genetic material

  9. Genetic diversity among ancient Nordic populations.

    Directory of Open Access Journals (Sweden)

    Linea Melchior

    Full Text Available Using established criteria for work with fossil DNA we have analysed mitochondrial DNA from 92 individuals from 18 locations in Denmark ranging in time from the Mesolithic to the Medieval Age. Unequivocal assignment of mtDNA haplotypes was possible for 56 of the ancient individuals; however, the success rate varied substantially between sites; the highest rates were obtained with untouched, freshly excavated material, whereas heavy handling, archeological preservation and storage for many years influenced the ability to obtain authentic endogenic DNA. While the nucleotide diversity at two locations was similar to that among extant Danes, the diversity at four sites was considerably higher. This supports previous observations for ancient Britons. The overall occurrence of haplogroups did not deviate from extant Scandinavians, however, haplogroup I was significantly more frequent among the ancient Danes (average 13% than among extant Danes and Scandinavians (approximately 2.5% as well as among other ancient population samples reported. Haplogroup I could therefore have been an ancient Southern Scandinavian type "diluted" by later immigration events. Interestingly, the two Neolithic samples (4,200 YBP, Bell Beaker culture that were typed were haplogroup U4 and U5a, respectively, and the single Bronze Age sample (3,300-3,500 YBP was haplogroup U4. These two haplogroups have been associated with the Mesolithic populations of Central and Northern Europe. Therefore, at least for Southern Scandinavia, our findings do not support a possible replacement of a haplogroup U dominated hunter-gatherer population by a more haplogroup diverse Neolithic Culture.

  10. Population and genomic lessons from genetic analysis of two Indian populations.

    Science.gov (United States)

    Juyal, Garima; Mondal, Mayukh; Luisi, Pierre; Laayouni, Hafid; Sood, Ajit; Midha, Vandana; Heutink, Peter; Bertranpetit, Jaume; Thelma, B K; Casals, Ferran

    2014-10-01

    Indian demographic history includes special features such as founder effects, interpopulation segregation, complex social structure with a caste system and elevated frequency of consanguineous marriages. It also presents a higher frequency for some rare mendelian disorders and in the last two decades increased prevalence of some complex disorders. Despite the fact that India represents about one-sixth of the human population, deep genetic studies from this terrain have been scarce. In this study, we analyzed high-density genotyping and whole-exome sequencing data of a North and a South Indian population. Indian populations show higher differentiation levels than those reported between populations of other continents. In this work, we have analyzed its consequences, by specifically assessing the transferability of genetic markers from or to Indian populations. We show that there is limited genetic marker portability from available genetic resources such as HapMap or the 1,000 Genomes Project to Indian populations, which also present an excess of private rare variants. Conversely, tagSNPs show a high level of portability between the two Indian populations, in contrast to the common belief that North and South Indian populations are genetically very different. By estimating kinship from mates and consanguinity in our data from trios, we also describe different patterns of assortative mating and inbreeding in the two populations, in agreement with distinct mating preferences and social structures. In addition, this analysis has allowed us to describe genomic regions under recent adaptive selection, indicating differential adaptive histories for North and South Indian populations. Our findings highlight the importance of considering demography for design and analysis of genetic studies, as well as the need for extending human genetic variation catalogs to new populations and particularly to those with particular demographic histories.

  11. Genetic variants associated with warfarin dosage in Kuwaiti population.

    Science.gov (United States)

    John, Sumi Elsa; Antony, Dinu; Eaaswarkhanth, Muthukrishnan; Hebbar, Prashantha; Alkayal, Fadi; Tuomilehto, Jaakko; Alsmadi, Osama; Thanaraj, Thangavel Alphonse

    2017-06-01

    Assessing the distinct prevalence or absence of genetic variants associated with differential response to the anticoagulant medication of warfarin in different population groups is actively pursued by pharmacogenomics community. Populations from Arabian Peninsula are underrepresented in such studies. By way of examining exome- and genome-wide genotype data from 1395 Arab individuals in Kuwait, we report distinct occurrence of warfarin response-related variants rs12460590_A/CYP2A7, rs2108622_T/CYP4F2, rs2884737_C/VKORC1 and distinct absence of rs11150606_C/PRSS53 in Kuwaiti population. The presented results in conjunction with similar literature reports on Qatari population enhance the worldwide understanding on population-specific distributions of genetic variants associated with warfarin drug dosage.

  12. Population structure and genetic diversity in natural populations of Theobroma speciosum Willd. Ex Spreng (Malvaceae).

    Science.gov (United States)

    Giustina, L D; Luz, L N; Vieira, F S; Rossi, F S; Soares-Lopes, C R A; Pereira, T N S; Rossi, A A B

    2014-02-14

    The genus Theobroma found in the Amazon region is composed of 22 species, including Theobroma speciosum, better known as cacauí. These species are constantly threatened by forest fragmentation caused by human activities and require conservation strategies and management aimed at preserving them in their natural environments. The main objective of this study was to analyze the population structure and genetic diversity within and between natural populations of T. speciosum by using ISSR molecular markers to understand the population structure of the species. Four natural populations belonging to the Amazon rainforest (BAC, CRO, FLA, and PNA), located in the State of Mato Grosso, were selected. Amplification reactions were performed using 15 ISSR primers. A total of 101 loci were found, of which 54.46% were polymorphic at the species level. The BAC population showed higher genetic diversity (H=0.095 and I=0.144) and higher percentage of polymorphism (28.71%). The populations showed an FST value of 0.604, indicating marked genetic differentiation. The highest genetic variation was found between populations. Gene flow was low between populations, indicating genetic isolation between populations.

  13. Population connectivity and genetic structure of burbot (Lota lota) populations in the Wind River Basin, Wyoming

    Science.gov (United States)

    Underwood, Zachary E.; Mandeville, Elizabeth G.; Walters, Annika W.

    2016-01-01

    Burbot (Lota lota) occur in the Wind River Basin in central Wyoming, USA, at the southwestern extreme of the species’ native range in North America. The most stable and successful of these populations occur in six glacially carved mountain lakes on three different tributary streams and one large main stem impoundment (Boysen Reservoir) downstream from the tributary populations. Burbot are rarely found in connecting streams and rivers, which are relatively small and high gradient, with a variety of potential barriers to upstream movement of fish. We used high-throughput genomic sequence data for 11,197 SNPs to characterize the genetic diversity, population structure, and connectivity among burbot populations on the Wind River system. Fish from Boysen Reservoir and lower basin tributary populations were genetically differentiated from those in the upper basin tributary populations. In addition, fish within the same tributary streams fell within the same genetic clusters, suggesting there is movement of fish between lakes on the same tributaries but that populations within each tributary system are isolated and genetically distinct from other populations. Observed genetic differentiation corresponded to natural and anthropogenic barriers, highlighting the importance of barriers to fish population connectivity and gene flow in human-altered linked lake-stream habitats.

  14. Alu polymorphic insertions reveal genetic structure of north Indian populations.

    Science.gov (United States)

    Tripathi, Manorama; Tripathi, Piyush; Chauhan, Ugam Kumari; Herrera, Rene J; Agrawal, Suraksha

    2008-10-01

    The Indian subcontinent is characterized by the ancestral and cultural diversity of its people. Genetic input from several unique source populations and from the unique social architecture provided by the caste system has shaped the current genetic landscape of India. In the present study 200 individuals each from three upper-caste and four middle-caste Hindu groups and from two Muslim populations in North India were examined for 10 polymorphic Alu insertions (PAIs). The investigated PAIs exhibit high levels of polymorphism and average heterozygosity. Limited interpopulation variance and genetic flow in the present study suggest admixture. The results of this study demonstrate that, contrary to common belief, the caste system has not provided an impermeable barrier to genetic exchange among Indian groups.

  15. A population genetic transect of Panicum hallii (Poaceae).

    Science.gov (United States)

    Lowry, David B; Purmal, Colin T; Juenger, Thomas E

    2013-03-01

    Understanding the relationship between climate, adaptation, and population structure is of fundamental importance to botanists because these factors are crucial for the evolution of biodiversity and the response of species to future climate change. Panicum hallii is an emerging model system for perennial grass and bioenergy research, yet very little is known about the relationship between climate and population structure in this system. • We analyzed geographic population differentiation across 39 populations of P. hallii along a longitudinal transect from the savannas of central Texas through the deserts of Arizona and New Mexico. A combination of morphological and genetic (microsatellite) analysis was used to explore patterns of population structure. • We found strong differentiation between high elevation western desert populations and lower elevation eastern populations of P. hallii, with a pronounced break in structure occurring in western Texas. In addition, we confirmed that there are high levels of morphological and genetic structure between previous recognized varieties (var. hallii and var. filipes) within this species. • The results of this study suggest that patterns of population structure within P. hallii may be driven by climatic variation over space. Overall, this study lays the groundwork for future studies on the genetics of local adaptation and reproductive isolation in this system.

  16. Population genetic structure of a colonising, triploid weed, Hieracium lepidulum.

    Science.gov (United States)

    Chapman, H; Robson, B; Pearson, M L

    2004-03-01

    Understanding the breeding system and population genetic structure of invasive weed species is important for biocontrol, and contributes to our understanding of the evolutionary processes associated with invasions. Hieracium lepidulum is an invasive weed in New Zealand, colonising a diverse range of habitats including native Nothofagus forest, pine plantations, scrubland and tussock grassland. It is competing with native subalpine and alpine grassland and herbfield vegetation. H. lepidulum is a triploid, diplosporous apomict, so theoretically all seed is clonal, and there is limited potential for the creation of variation through recombination. We used intersimple sequence repeats (ISSRs) to determine the population genetic structure of New Zealand populations of H. lepidulum. ISSR analysis of five populations from two regions in the South Island demonstrated high intrapopulation genotypic diversity, and high interpopulation genetic structuring; PhiST = 0.54 over all five populations. No private alleles were found in any of the five populations, and allelic differentiation was correlated to geographic distance. Cladistic compatibility analysis indicated that both recombination and mutation were important in the creation of genotypic diversity. Our data will contribute to any biocontrol program developed for H. lepidulum. It will also be a baseline data set for future comparisons of genetic structure during the course of H. lepidulum invasions.

  17. Genetic affinities between endogamous and inbreeding populations of Uttar Pradesh

    Directory of Open Access Journals (Sweden)

    Borkar Minal

    2007-04-01

    Full Text Available Abstract Background India has experienced several waves of migration since the Middle Paleolithic. It is believed that the initial demic movement into India was from Africa along the southern coastal route, approximately 60,000–85,000 years before present (ybp. It has also been reported that there were two other major colonization which included eastward diffusion of Neolithic farmers (Elamo Dravidians from Middle East sometime between 10,000 and 7,000 ybp and a southern dispersal of Indo Europeans from Central Asia 3,000 ybp. Mongol entry during the thirteenth century A.D. as well as some possible minor incursions from South China 50,000 to 60,000 ybp may have also contributed to cultural, linguistic and genetic diversity in India. Therefore, the genetic affinity and relationship of Indians with other world populations and also within India are often contested. In the present study, we have attempted to offer a fresh and immaculate interpretation on the genetic relationships of different North Indian populations with other Indian and world populations. Results We have first genotyped 20 tetra-nucleotide STR markers among 1800 north Indian samples of nine endogamous populations belonging to three different socio-cultural strata. Genetic distances (Nei's DA and Reynold's Fst were calculated among the nine studied populations, Caucasians and East Asians. This analysis was based upon the allelic profile of 20 STR markers to assess the genetic similarity and differences of the north Indian populations. North Indians showed a stronger genetic relationship with the Europeans (DA 0.0341 and Fst 0.0119 as compared to the Asians (DA 0.1694 and Fst – 0.0718. The upper caste Brahmins and Muslims were closest to Caucasians while middle caste populations were closer to Asians. Finally, three phylogenetic assessments based on two different NJ and ML phylogenetic methods and PC plot analysis were carried out using the same panel of 20 STR markers and 20

  18. Quantifying population genetic differentiation from next-generation sequencing data

    DEFF Research Database (Denmark)

    Fumagalli, Matteo; Vieira, Filipe G.; Korneliussen, Thorfinn Sand;

    2013-01-01

    Over the last few years, new high-throughput DNA sequencing technologies have dramatically increased speed and reduced sequencing costs. However, the use of these sequencing technologies is often challenged by errors and biases associated with the bioinformatical methods used for analyzing the da...... individuals, suggesting that employing this new method is useful for investigating the genetic relationships of populations sampled at low coverage....... method for quantifying population genetic differentiation from next-generation sequencing data. In addition, we present a strategy to investigate population structure via Principal Components Analysis. Through extensive simulations, we compare the new method herein proposed to approaches based...... on genotype calling and demonstrate a marked improvement in estimation accuracy for a wide range of conditions. We apply the method to a large-scale genomic data set of domesticated and wild silkworms sequenced at low coverage. We find that we can infer the fine-scale genetic structure of the sampled...

  19. Quasispecies theory in the context of population genetics

    Directory of Open Access Journals (Sweden)

    Wilke Claus O

    2005-08-01

    Full Text Available Abstract Background A number of recent papers have cast doubt on the applicability of the quasispecies concept to virus evolution, and have argued that population genetics is a more appropriate framework to describe virus evolution than quasispecies theory. Results I review the pertinent literature, and demonstrate for a number of cases that the quasispecies concept is equivalent to the concept of mutation-selection balance developed in population genetics, and that there is no disagreement between the population genetics of haploid, asexually-replicating organisms and quasispecies theory. Conclusion Since quasispecies theory and mutation-selection balance are two sides of the same medal, the discussion about which is more appropriate to describe virus evolution is moot. In future work on virus evolution, we would do good to focus on the important questions, such as whether we can develop accurate, quantitative models of virus evolution, and to leave aside discussions about the relative merits of perfectly equivalent concepts.

  20. gPGA: GPU Accelerated Population Genetics Analyses.

    Directory of Open Access Journals (Sweden)

    Chunbao Zhou

    Full Text Available The isolation with migration (IM model is important for studies in population genetics and phylogeography. IM program applies the IM model to genetic data drawn from a pair of closely related populations or species based on Markov chain Monte Carlo (MCMC simulations of gene genealogies. But computational burden of IM program has placed limits on its application.With strong computational power, Graphics Processing Unit (GPU has been widely used in many fields. In this article, we present an effective implementation of IM program on one GPU based on Compute Unified Device Architecture (CUDA, which we call gPGA.Compared with IM program, gPGA can achieve up to 52.30X speedup on one GPU. The evaluation results demonstrate that it allows datasets to be analyzed effectively and rapidly for research on divergence population genetics. The software is freely available with source code at https://github.com/chunbaozhou/gPGA.