Simultaneous Assay of Isotopic Enrichment and Concentration of Guanidinoacetate and Creatine by Gas Chromatography-Mass Spectrometry

Science.gov (United States)

Kasumov, Takhar; Gruca, Lourdes L.; Dasarathy, Srinivasan; Kalhan, Satish C.

2012-01-01

A gas chromatographic-mass spectrometric (GC-MS) method for the simultaneous measurement of isotopic enrichment and concentration of guanidinoacetic acid and creatine in plasma sample for kinetic studies is reported. The method, based on preparation of the bis(trifluoromethyl)-pyrimidine methyl ester derivatives of guanidinoacetic acid and creatine, is robust and sensitive. The lowest measurable m1 and m3 enrichment for guanidinoacetic acid and creatine, respectively, was 0.3%. The calibration curves for measurements of concentration were linear over a range of 0.5-250 μM guanidinoacetic acid and 2-500 μM for creatine. The method was reliable for inter-assay and intra-assay precision, accuracy and linearity. The technique was applied in a healthy adult to determine in vivo fractional synthesis rate of creatine using primed- constant rate infusion of [1-13C]glycine. It was found that isotopic enrichment of guanidinoacetic acid reached plateau by 30 min of infusion of [1-13C]glycine, indicating either a small pool size or a rapid turnover rate or both, of guanidinoacetic acid. In contrast, tracer appearance in creatin was slow (slope: 0.00097), suggesting a large pool size and a slow rate of synthesis of creatine. This method can be used to estimate rate of synthesis of creatine in-vivo in human and animal studies. PMID:19646413

Detection of induced male germline mutation: Correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays

Energy Technology Data Exchange (ETDEWEB)

Singer, Timothy M. [Mutagenesis Section, Environmental and Occupational Toxicology Division, Safe Environments Programme, 0803A, Health Canada, Ottawa, Ont., K1A 0K9 (Canada); Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ont., K1S 5B6 (Canada); Lambert, Iain B. [Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ont., K1S 5B6 (Canada); Williams, Andrew [Biostatistics and Epidemiology Division, Safe Environments Programme, 6604B, Health Canada, Ottawa, Ont., K1A 0K9 (Canada); Douglas, George R. [Mutagenesis Section, Environmental and Occupational Toxicology Division, Safe Environments Programme, 0803A, Health Canada, Ottawa, Ont., K1A 0K9 (Canada); Yauk, Carole L. [Mutagenesis Section, Environmental and Occupational Toxicology Division, Safe Environments Programme, 0803A, Health Canada, Ottawa, Ont., K1A 0K9 (Canada)]. E-mail: carole_yauk@hc-sc.gc.ca

2006-06-25

Several rodent assays are capable of monitoring germline mutation. These include traditional assays, such as the dominant lethal (DL) assay, the morphological specific locus (SL) test and the heritable translocation (HT) assay, and two assays that have been developed more recently-the expanded simple tandem repeat (ESTR) and transgenic rodent (TGR) mutation assays. In this paper, we have compiled the limited amount of experimental data that are currently available to make conclusions regarding the comparative ability of the more recently developed assays to detect germline mutations induced by chemical and radiological agents. The data suggest that ESTR and TGR assays are generally comparable with SL in detecting germline mutagenicity induced by alkylating agents and radiation, though TGR offered less sensitivity than ESTR in some cases. The DL and HT assays detect clastogenic events and are most susceptible to mutations arising in post-spermatogonial cells, and they may not provide the best comparisons with TGR and ESTR instability. The measurement of induced ESTR instability represents a relatively sensitive method of identifying agents causing germline mutation in rodents, and may also be useful for bio-monitoring exposed individuals in the human population. Any future use of the TGR and ESTR germline mutation assays in a regulatory testing context will entail more robust and extensive characterization of assay performance. This will require substantially more data, including experiments measuring multiple endpoints, a greatly expanded database of chemical agents and a focus on characterizing stage-specific activity of mutagens in these assays, preferably by sampling epididymal sperm exposed at defined pre-meiotic, meiotic and post-meiotic stages of development.

Detection of induced male germline mutation: Correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays

International Nuclear Information System (INIS)

Singer, Timothy M.; Lambert, Iain B.; Williams, Andrew; Douglas, George R.; Yauk, Carole L.

2006-01-01

Several rodent assays are capable of monitoring germline mutation. These include traditional assays, such as the dominant lethal (DL) assay, the morphological specific locus (SL) test and the heritable translocation (HT) assay, and two assays that have been developed more recently-the expanded simple tandem repeat (ESTR) and transgenic rodent (TGR) mutation assays. In this paper, we have compiled the limited amount of experimental data that are currently available to make conclusions regarding the comparative ability of the more recently developed assays to detect germline mutations induced by chemical and radiological agents. The data suggest that ESTR and TGR assays are generally comparable with SL in detecting germline mutagenicity induced by alkylating agents and radiation, though TGR offered less sensitivity than ESTR in some cases. The DL and HT assays detect clastogenic events and are most susceptible to mutations arising in post-spermatogonial cells, and they may not provide the best comparisons with TGR and ESTR instability. The measurement of induced ESTR instability represents a relatively sensitive method of identifying agents causing germline mutation in rodents, and may also be useful for bio-monitoring exposed individuals in the human population. Any future use of the TGR and ESTR germline mutation assays in a regulatory testing context will entail more robust and extensive characterization of assay performance. This will require substantially more data, including experiments measuring multiple endpoints, a greatly expanded database of chemical agents and a focus on characterizing stage-specific activity of mutagens in these assays, preferably by sampling epididymal sperm exposed at defined pre-meiotic, meiotic and post-meiotic stages of development

Portable and quantitative point-of-care monitoring of Escherichia coli O157:H7 using a personal glucose meter based on immunochromatographic assay.

Science.gov (United States)

Huang, Haoran; Zhao, Guangying; Dou, Wenchao

2018-06-01

Here we innovate a portable and quantitative immunochromatographic assay (ICA) with a personal glucose meter (PGM) as readout for the detection of Escherichia coli O157:H7 (E. coli O157:H7). The carboxyl group coated Fe 3 O 4 nanoparticles (MNPs) were synthesized by a one pot method and used as carriers of invertase and monoclonal antibody against E. coli O157:H7. Initially, the invertase and antibody double functionalized MNPs (Invertase-MNPs-IgG) conjugates were prepared and used as label probe in this assay system. Before laminating onto the baking card, the absorbent pad was soaked in sucrose solution and desiccated. MNPs produced brown band at the detection zone of the ICA when acting as direct labels. As they were also coupled with invertase, the invertase catalyzed the hydrolysis of sucrose on the absorbent pad into glucose, which was detected by the PGM. To increase the sensitivity, antibody functionalized MNPs were used to enrich E. coli O157:H7 from sample solution. The innovative aspect of this approach lies in the visualization and quantification of E. coli O157:H7 through Invertase-MNPs-IgG and the detection of glucose concentration using PGM. Although the feasibility is demonstrated using E. coli O157:H7 as a model analyte, this approach can be easily developed to be a universal analysis system and applied to detection of a wide variety of foodborne pathogens and protein biomarkers. This study proposed a qualitative and quantitative analysis device for the clinic diagnostics and food safety analysis. Copyright © 2018 Elsevier B.V. All rights reserved.

Stationary and protable instruments for assay of HEU [highly enriched uranium] solids holdup

International Nuclear Information System (INIS)

Russo, P.A.; Sprinkle, J.K. Jr.; Stephens, M.M.; Brumfield, T.L.; Gunn, C.S.; Watson, D.R.

1987-01-01

Two NaI(Tl)-based instruments, one stationary and one portable, designed for automated assay of highly enriched uranium (HEU) solids holdup, are being evaluated at the scrap recovery facility of the Oak Ridge Y-12 Plant. The stationary instrument, a continuous monitor of HEU within the filters of the chip burner exhaust system, measures the HEU deposits that accumulate erratically and rapidly during chip burner operation. The portable system was built to assay HEU in over 100 m of elevated piping used to transfer UO 3 , UO 2 , and UF 4 powder to, from, and between the fluid bed conversion furnances and the powder storage hoods. Both instruments use two detector heads. Both provide immediate automatic readout of accumulated HEU mass. The 186-keV 235 U gamma ray is the assay signature, and the 60-keV gamma ray from an 241 Am source attached to each detector is used to normalize the 186-keV rate. The measurement geometries were selected for compatibility with simple calibration models. The assay calibrations were calculated from these models and were verified and normalized with measurements of HEU standards built to match geometries of uniform accumulations on the surfaces of the process equipment. This instrumentation effort demonstrates that simple calibration models can often be applied to unique measurement geometries, minimizing the otherwise unreasonable requirements for calibration standards and allowing extension of the measurements to other process locations

Attacks and their Defenses for Advanced Metering Infrastructure

DEFF Research Database (Denmark)

Lighari, Sheeraz Niaz; Hussain, Dil Muhammad Akbar; Bak-Jensen, Birgitte

2014-01-01

The smart grid is the digitized, modernized, updated version of archaic traditional electric grid. Advanced Metering Infrastructure (AMI) is an imperative part of the smart grid. It has replaced legacy metering, as it reports the energy consumption to the utility automatically through communicati...

Evaluation of a combined macrophyte–epiphyte bioassay for assessing nutrient enrichment in the Portneuf River, Idaho, USA

Science.gov (United States)

Ray, Andrew M.; Mebane, Christopher A.; Raben, Flint; Irvine, Kathryn M.; Marcarelli, Amy M.

2014-01-01

We describe and evaluate a laboratory bioassay that uses Lemna minor L. and attached epiphytes to characterize the status of ambient and nutrient-enriched water from the Portneuf River, Idaho. Specifically, we measured morphological (number of fronds, longest surface axis, and root length) and population-level (number of plants and dry mass) responses of L. minor and community-level (ash-free dry mass [AFDM] and chlorophyll a [Chl a]) responses of epiphytes to nutrient enrichment. Overall, measures of macrophyte biomass and abundance increased with increasing concentrations of dissolved phosphorus (P) and responded more predictably to nutrient enrichment than morphological measures. Epiphyte AFDM and Chl a were also greatest in P-enriched water; enrichments of N alone produced no measurable epiphytic response. The epiphyte biomass response did not directly mirror macrophyte biomass responses, illustrating the value of a combined macrophyte–epiphyte assay to more fully evaluate nutrient management strategies. Finally, the most P-enriched waters not only supported greater standing stocks of macrophyte and epiphytes but also had significantly higher water column dissolved oxygen and dissolved organic carbon concentrations and a lower pH. Advantages of this macrophyte–epiphyte bioassay over more traditional single-species assays include the use of a more realistic level of biological organization, a relatively short assay schedule (~10 days), and the inclusion of multiple biological response and water-quality measures.

DEVELOPMENT OF ENRICHMENT VERIFICATION ASSAY BASED ON THE AGE AND 235U AND 238U ACTIVITIES OF THE SAMPLES

International Nuclear Information System (INIS)

AL-YAMAHI, H.; EL-MONGY, S.A.

2008-01-01

Development of the enrichment verification methods is the backbone of the nuclear materials safeguards skeleton. In this study, the 235U percentage of depleted , natural and very slightly enriched uranium samples were estimated based on the sample age and the measured activity of 235U and 238U. The HpGe and NaI spectrometry were used for samples assay. A developed equation was derived to correlate the sample age and 235U and 238U activities with the enrichment percentage (E%). The results of the calculated E% by the deduced equation and the target E% values were found to be similar and within 0.58 -1.75% bias in the case of HpGe measurements. The correlation between them was found to be very sharp. The activity was also calculated based on the measured sample count rate and the efficiency at the gamma energies of interest. The correlation between the E% and the 235U activity was estimated and found to be linearly sharp. The results obtained by NaI was found to be less accurate than these obtained by HpGe. The bias in the case of NaI assay was in the range from 6.398% to 22.8% for E% verification

Transforming the blood glucose meter into a general healthcare meter for in vitro diagnostics in mobile health.

Science.gov (United States)

Lan, Tian; Zhang, Jingjing; Lu, Yi

2016-01-01

Recent advances in mobile network and smartphones have provided an enormous opportunity for transforming in vitro diagnostics (IVD) from central labs to home or other points of care (POC). A major challenge to achieving the goal is a long time and high costs associated with developing POC IVD devices in mobile Health (mHealth). Instead of developing a new POC device for every new IVD target, we and others are taking advantage of decades of research, development, engineering and continuous improvement of the blood glucose meter (BGM), including those already integrated with smartphones, and transforming the BGM into a general healthcare meter for POC IVDs of a wide range of biomarkers, therapeutic drugs and other analytical targets. In this review, we summarize methods to transduce and amplify selective binding of targets by antibodies, DNA/RNA aptamers, DNAzyme/ribozymes and protein enzymes into signals such as glucose or NADH that can be measured by commercially available BGM, making it possible to adapt many clinical assays performed in central labs, such as immunoassays, aptamer/DNAzyme assays, molecular diagnostic assays, and enzymatic activity assays onto BGM platform for quantification of non-glucose targets for a wide variety of IVDs in mHealth. Copyright © 2016 Elsevier Inc. All rights reserved.

Community Net Energy Metering: How Novel Policies Expand Benefits of Net Metering to Non-Generators

Energy Technology Data Exchange (ETDEWEB)

Rose, James; Varnado, Laurel

2009-04-01

As interest in community solutions to renewable energy grows, more states are beginning to develop policies that encourage properties with more than one meter to install shared renewable energy systems. State net metering policies are evolving to allow the aggregation of multiple meters on a customer’s property and to dissolve conventional geographical boundaries. This trend means net metering is expanding out of its traditional function as an enabling incentive to offset onsite customer load at a single facility. This paper analyzes community net energy metering (CNEM) as an emerging vehicle by which farmers, neighborhoods, and municipalities may more easily finance and reap the benefits of renewable energy. Specifically, it aims to compare and contrast the definition of geographical boundaries among different CNEM models and examine the benefits and limitations of each approach. As state policies begin to stretch the geographic boundaries of net metering, they allow inventive solutions to encourage renewable energy investment. This paper attempts to initiate the conversation on this emerging policy mechanism and offers recommendations for further development of these policies.

Uranium enrichment plans

International Nuclear Information System (INIS)

Gagne, R.W.; Thomas, D.C.

1977-01-01

The status of existing uranium enrichment contracts in the US is reviewed and expected natural uranium requirements for existing domestic uranium enrichment contracts are evaluated. Uncertainty in natural uranium requirements associated with requirements-type and fixed-commitment type contracts is discussed along with implementation of variable tails assay

Design of Remote Heat-Meter System Based on Trusted Technology

Science.gov (United States)

Yu, Changgeng; Lai, Liping

2018-03-01

This article presents a proposal of a heat meter and remote meter reading system for the disadvantages of the hackers very easily using eavesdropping, tampering, replay attack of traditional remote meter reading system. The system selects trusted technology such as, the identity authentication, integrity verifying, and data protection. By the experiments, it is proved that the remote meter reading system of the heat meter can be used to verify the feasibility of the technology, and verify the practicability and operability of data protection technology.

Development of a real-time multiplex PCR assay for the detection of multiple Salmonella serotypes in chicken samples

Directory of Open Access Journals (Sweden)

Whyte Paul

2008-09-01

Full Text Available Abstract Background A real-time multiplex PCR assay was developed for the detection of multiple Salmonella serotypes in chicken samples. Poultry-associated serotypes detected in the assay include Enteritidis, Gallinarum, Typhimurium, Kentucky and Dublin. The traditional cultural method according to EN ISO 6579:2002 for the detection of Salmonella in food was performed in parallel. The real-time PCR based method comprised a pre-enrichment step in Buffered Peptone Water (BPW overnight, followed by a shortened selective enrichment in Rappaport Vasilliadis Soya Broth (RVS for 6 hours and subsequent DNA extraction. Results The real-time multiplex PCR assay and traditional cultural method showed 100% inclusivity and 100% exclusivity on all strains tested. The real-time multiplex PCR assay was as sensitive as the traditional cultural method in detecting Salmonella in artificially contaminated chicken samples and correctly identified the serotype. Artificially contaminated chicken samples resulted in a detection limit of between 1 and 10 CFU per 25 g sample for both methods. A total of sixty-three naturally contaminated chicken samples were investigated by both methods and relative accuracy, relative sensitivity and relative specificity of the real-time PCR method were determined to be 89, 94 and 87%, respectively. Thirty cultures blind tested were correctly identified by the real-time multiplex PCR method. Conclusion Real-time PCR methodology can contribute to meet the need for rapid identification and detection methods in food testing laboratories.

Immunochromatographic strip assay for the rapid and sensitive detection of Salmonella Typhimurium in artificially contaminated tomato samples.

Science.gov (United States)

Shukla, Shruti; Leem, Hyerim; Lee, Jong-Suk; Kim, Myunghee

2014-06-01

This study was designed to confirm the applicability of a liposome-based immunochromatographic assay for the rapid detection of Salmonella enterica subsp. enterica serovar Typhimurium (Salmonella Typhimurium) in artificially contaminated tomato samples. To determine the detection limit and pre-enrichment incubation time (10, 12, and 18 h pre-enrichment in 1% buffered peptone water), the tests were performed with different cell numbers of Salmonella Typhimurium (3 × 10(0), 3 × 10(1), 3 × 10(2), and 3 × 10(3) CFU·mL(-1)) inoculated into 25 g of crushed tomato samples. The assay was able to detect as few as 30 Salmonella Typhimurium cells per 25 g of tomato samples (1.2 cells·g(-1)) after 12 h pre-enrichment incubation. Moreover, when the developed assay was compared with traditional morphological and biochemical culture-based methods as well as colloidal gold nanoparticle-based commercial test strips, the developed assay yielded positive results for the detection of Salmonella Typhimurium within a shorter period time. These findings confirm that the developed assay may have practical application for the sensitive detection of Salmonella Typhimurium in various food samples, including raw vegetables, with a relatively low detection limit and shorter analysis time.

Enrichment allows identification of diverse, rare elements in metagenomic resistome-virulome sequencing.

Science.gov (United States)

Noyes, Noelle R; Weinroth, Maggie E; Parker, Jennifer K; Dean, Chris J; Lakin, Steven M; Raymond, Robert A; Rovira, Pablo; Doster, Enrique; Abdo, Zaid; Martin, Jennifer N; Jones, Kenneth L; Ruiz, Jaime; Boucher, Christina A; Belk, Keith E; Morley, Paul S

2017-10-17

Shotgun metagenomic sequencing is increasingly utilized as a tool to evaluate ecological-level dynamics of antimicrobial resistance and virulence, in conjunction with microbiome analysis. Interest in use of this method for environmental surveillance of antimicrobial resistance and pathogenic microorganisms is also increasing. In published metagenomic datasets, the total of all resistance- and virulence-related sequences accounts for enrichment system that incorporates unique molecular indices to count DNA molecules and correct for enrichment bias. The use of the bait-capture and enrichment system significantly increased on-target sequencing of the resistome-virulome, enabling detection of an additional 1441 gene accessions and revealing a low-abundance portion of the resistome-virulome that was more diverse and compositionally different than that detected by more traditional metagenomic assays. The low-abundance portion of the resistome-virulome also contained resistance genes with public health importance, such as extended-spectrum betalactamases, that were not detected using traditional shotgun metagenomic sequencing. In addition, the use of the bait-capture and enrichment system enabled identification of rare resistance gene haplotypes that were used to discriminate between sample origins. These results demonstrate that the rare resistome-virulome contains valuable and unique information that can be utilized for both surveillance and population genetic investigations of resistance. Access to the rare resistome-virulome using the bait-capture and enrichment system validated in this study can greatly advance our understanding of microbiome-resistome dynamics.

Determining antioxidant activities of lactobacilli cell-free supernatants by cellular antioxidant assay: a comparison with traditional methods.

Directory of Open Access Journals (Sweden)

Jiali Xing

Full Text Available Antioxidant activity of lactic acid bacteria is associated with multiple health-protective effects. Traditional indexes of chemical antioxidant activities poorly reflect the antioxidant effects of these bacteria in vivo. Cellular antioxidant activity (CAA assay was used in this study to determine the antioxidant activity of cell-free supernatants (CFSs of 10 Lactobacillus strains. The performance of the CAA assay was compared with that of four chemical antioxidant activity assays, namely, DPPH radical scavenging, hydroxyl radical scavenging (HRS, reducing power (RP, and inhibition of linoleic acid peroxidation (ILAP. Results of the CAA assay were associated with those of DPPH and ILAP assays, but not with those of RP and HRS assays. The inter- and intra-specific antioxidant activities of CFS were characterized by chemical and CAA assays. L. rhamnosus CCFM 1107 displayed a high antioxidative effect similar to positive control L. rhamnosus GG ATCC 53103 in all of the assays. The CAA assay is a potential method for the detection of antioxidant activities of lactobacilli CFSs.

A Study on Watt-hour Meter Data Acquisition Method Based on RFID Technology

Science.gov (United States)

Chen, Xiangqun; Huang, Rui; Shen, Liman; Chen, Hao; Xiong, Dezhi; Xiao, Xiangqi; Liu, Mouhai; Xu, Renheng

2018-03-01

Considering that traditional watt-hour meter data acquisition was subjected to the influence of distance and occlusion, a watt-hour meter data acquisition method based on RFID technology was proposed in this paper. In detail, RFID electronic tag was embedded in the watt-hour meter to identify the meter and record electric energy information, which made RFID based wireless data acquisition for watt-hour meter come true. Eventually, overall lifecycle management of watt-hour meter is realized.

A Novel Smart Meter Controlling System with Dynamic IP Addresses

DEFF Research Database (Denmark)

Manembu, Pinrolinvic; Welang, Brammy; Kalua Lapu, Aditya

2017-01-01

Smart meters are the electronic devices for measuring energy consumption in real time. Usually, static public IP addresses are allocated to realize the point-to-point (P2P) communication and remote controlling for smart metering systems. This, however, restricts the wide deployment of smart meters......, due to the deficiency of public IP resources. This paper proposes a novel subscription-based communication architecture for the support of dynamic IP addresses and group controlling of smart meters. The paper evaluates the proposed architecture by comparing the traditional P2P architecture...

Monte Carlo calculational design of an NDA instrument for the assay of waste products from high enriched uranium spent fuels

International Nuclear Information System (INIS)

Eccleston, G.W.; Schrandt, R.G.; MacDonald, J.L.; Cverna, F.H.

1979-01-01

The Monte Carlo design of the waste assay region of a dual assay system, to be installed at the Fluorinal and Storage Facility, is described. The instrument will be used by the facility operator to assay high-enriched spent fuel packages and waste solids produced from dissolution of the fuels. The fissile content discharged in the waste is expected to vary between 0 and 400 g of 235 U. Material accountability measurements of the waste must be obtained in the presence of large neutron (0.5 x 10 6 n/s) and gamma (50,000 R/hr) backgrounds. The assay system employs fast-neutron irradiation of the sample, using a 5 mg 252 Cf source, followed by delayed neutron counting after the source is transferred to storage. Calculations indicate a +-4-g (2 sigma) assay for a waste canister containing 300 g of 235 U is achievable with an end-of-life (1 mg) 252 Cf source and a background rate of 0.5 x 10 6 n/s

Medium Access Control for Thermal Energy Harvesting in Advanced Metering Infrastructures

DEFF Research Database (Denmark)

Vithanage, Madava D.; Fafoutis, Xenofon; Andersen, Claus Bo

2013-01-01

In this paper we investigate the feasibility of powering wireless metering devices, namely heat cost allocators, by thermal energy harvested from radiators. The goal is to take a first step toward the realization of Energy-Harvesting Advanced Metering Infrastructures (EH-AMIs). While traditional...

Fast Enrichment Screening for Safeguards Applications

International Nuclear Information System (INIS)

Simpson, A.; McElhaney, S.

2010-01-01

bremsstrahlung radiation and neutron emissions are considered in addition to photopeak ratio analysis. Benchmark comparisons are performed against well-established enrichment analysis methods such as PC-FRAM, MGAU, and the Enrichment Meter. The suitability/limitations of the more traditional methods is discussed. (author)

Technical note: Validation of the BHBCheck blood β-hydroxybutyrate meter as a diagnostic tool for hyperketonemia in dairy cows.

Science.gov (United States)

Sailer, K J; Pralle, R S; Oliveira, R C; Erb, S J; Oetzel, G R; White, H M

2018-02-01

Accurate cow-side blood β-hydroxybutyrate (BHB) detection meters are valuable tools for rapid diagnosis of hyperketonemia. The main objective of this study was to compare the blood BHB measured in whole blood by the BHBCheck meter (PortaCheck, Moorestown, NJ) to a previously validated meter, Precision Xtra meter (Abbott Laboratories, Abbott Park, IL) and a colorimetric laboratory assay. Samples (n = 426) were collected from postpartum primiparous and multiparous Holstein cows (n = 79 cows) enrolled in 1 of 2 experiments (Exp) with different sampling schedules (Exp 1: n = 39 cows, 58 samples; Exp 2: n = 40 cows, 368 samples). In both Exp, whole-blood samples were collected from the coccygeal vessels after morning milking, before morning feeding. Blood samples were used immediately for BHB quantification via the BHBCheck meter and the Precision Xtra meter. Blood was also collected into evacuated tubes containing no additive (Exp 1) or potassium oxalate/sodium fluoride (Exp 2), which were centrifuged for serum or plasma separation and stored at -20°C for subsequent analysis. Laboratory quantification of BHB concentration was done by the BHB LiquiColor Assay (EKF Diagnostics-Stanbio, Boerne, TX; certified for serum and plasma). Data were analyzed by UNIVARIATE, CORR, FREQ, REG, and LOGISTIC procedures of SAS 9.4 (SAS Institute Inc., Cary, NC). Within this sample set, average parity was 3.3 lactations and DIM was 14 d. The proportion of samples classified as hyperketonemia (BHB ≥1.2 mmol/L) was 25, 28, and 31% as determined by the colorimetric assay, BHBCheck meter, and Precision Xtra meter, respectively. The correlation for BHBCheck meter BHB concentration compared with the colorimetric assay concentrations was r = 0.96, with a sensitivity of 91% and specificity of 93%. Correlation, sensitivity, and specificity of the Precision Xtra meter concentrations were 0.97, 98%, and 92%, respectively. Bland-Altman plots demonstrated minimal bias for both meters. Area under

233U Assay A Neutron NDA System

International Nuclear Information System (INIS)

Hensley, D.C.; Lucero, A.J.; Pierce, L.

1998-01-01

The assay of highly enriched 233 U material presents some unique challenges. Techniques which apply to the assay of materials of Pu or enriched 235 U do not convert easily over to the assay of 233 U. A specialized neutron assay device is being fabricated to exploit the singles neutron signal, the weak correlated neutron signal, and an active correlated signal. These pieces of information when combined with γ ray isotopics information should give a good overall determination of 233 U material now stored in bldg. 3019 at the Oak Ridge National Laboratory

Enriched uranium sales: effect on supply industry

International Nuclear Information System (INIS)

Andersen, R.K.

1985-01-01

The subject is covered in sections: introduction (combined effect of low-enriched uranium (LEU) inventory sales and utility services enrichment contract terms); enrichment market overview; enrichment market dynamics; the reaction of the US Department of Energy; elimination of artificial demand; draw down of inventories; purchase and sale of LEU inventories; tails assay option; unfulfilled requirements for U 3 O 8 ; conclusions. (U.K.)

Continuous monitoring of variations in the 235U enrichment of uranium in the header pipework of a centrifuge enrichment plant

International Nuclear Information System (INIS)

Packer, T.W.

1991-01-01

Non-destructive assay equipment, based on gamma-ray spectrometry and x-ray fluorescence analysis has previously been developed for confirming the presence of low enriched uranium in the header pipework of UF 6 gas centrifuge enrichment plants. However inspections can only be carried out occasionally on a limited number of pipes. With the development of centrifuge enrichment technology it has been suggested that more frequent, or ideally, continuous measurements should be made in order to improve safeguards assurance between inspections. For this purpose we have developed non-destructive assay equipment based on continuous gamma-ray spectrometry and x-ray transmission measurements. This equipment is suitable for detecting significant changes in the 235 U enrichment of uranium in the header pipework of new centrifuge enrichment plants. Results are given in this paper of continuous measurements made in the laboratory and also on header pipework of a centrifuge enrichment plant at Capenhurst

MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples.

Science.gov (United States)

McCarthy, David; Pulverer, Walter; Weinhaeusel, Andreas; Diago, Oscar R; Hogan, Daniel J; Ostertag, Derek; Hanna, Michelle M

2016-06-01

Development of a sensitive method for DNA methylation profiling and associated mutation detection in clinical samples. Formalin-fixed and paraffin-embedded tumors received by clinical laboratories often contain insufficient DNA for analysis with bisulfite or methylation sensitive restriction enzymes-based methods. To increase sensitivity, methyl-CpG DNA capture and Coupled Abscription PCR Signaling detection were combined in a new assay, MethylMeter(®). Gliomas were analyzed for MGMT methylation, glioma CpG island methylator phenotype and IDH1 R132H. MethylMeter had 100% assay success rate measuring all five biomarkers in formalin-fixed and paraffin-embedded tissue. MGMT methylation results were supported by survival and mRNA expression data. MethylMeter is a sensitive and quantitative method for multitarget DNA methylation profiling and associated mutation detection. The MethylMeter-based GliomaSTRAT assay measures methylation of four targets and one mutation to simultaneously grade gliomas and predict their response to temozolomide. This information is clinically valuable in management of gliomas.

Enriching Traditional Cataloging for Improved Access to Information:Library of Congress Tables of Contents Projects

Directory of Open Access Journals (Sweden)

John D. Byrum Jr.

2006-03-01

Full Text Available Traditionally, standard catalog records have provided bibliographic data that mostly address the basic features of library resources. At the same time, catalogs have offered access to these records through a limited array of names, titles, series, subject headings, class numbers, and a relatively small number of keywords contained within descriptions. Today’s catalog users expect access to information well beyond what can be offered by traditional approaches to bibliographic description and access. By pursuing a suite of projects, the Library of Congress (LC has responded to the challenge of enticing patrons to continue to include the online catalog among the tools they use for information retrieval. Drawing extensively on the power of automation, staff of LC’s Bibliographic Enrichment Advisory Team (BEAT have created and implemented a variety of initiatives to link researchers, catalogs, and Web resources; increase the content of the catalog record; and link the catalog to electronic resources. BEAT’s ongoing work demonstrates how, in the electronic era, it is possible to provide new and improved ways to capitalize on traditional services in the digital age. This paper will illustrate these points by focusing on BEAT’s tables of contents projects to demonstrate how library automation can make significant bibliographic enhancement efforts quick, easy, and affordable to achieve.

Uranium Enrichment, an overview

International Nuclear Information System (INIS)

Coates, J.H.

1994-01-01

This general presentation on uranium enrichment will be followed by lectures on more specific topics including descriptions of enrichment processes and assessments of the prevailing commercial and industrial situations. I shall therefore avoid as much as possible duplications with these other lectures, and rather dwell on: some theoretical aspects of enrichment in general, underlying the differences between statistical and selective processes, a review and comparison between enrichment processes, remarks of general order regarding applications, the proliferation potential of enrichment. It is noteworthy that enrichment: may occur twice in the LWR fuel cycle: first by enriching natural uranium, second by reenriching uranium recovered from reprocessing, must meet LWR requirements, and in particular higher assays required by high burn up fuel elements, bears on the structure of the entire front part of the fuel cycle, namely in the conversion/reconversion steps only involving UF 6 for the moment. (author). tabs., figs., 4 refs

Smart Meter Data Analytics: Systems, Algorithms and Benchmarking

DEFF Research Database (Denmark)

Liu, Xiufeng; Golab, Lukasz; Golab, Wojciech

2016-01-01

the proposed benchmark using five representative platforms: a traditional numeric computing platform (Matlab), a relational DBMS with a built-in machine learning toolkit (PostgreSQL/MADlib), a main-memory column store (“System C”), and two distributed data processing platforms (Hive and Spark/Spark Streaming......Smart electricity meters have been replacing conventional meters worldwide, enabling automated collection of fine-grained (e.g., every 15 minutes or hourly) consumption data. A variety of smart meter analytics algorithms and applications have been proposed, mainly in the smart grid literature......-line feature extraction and model building as well a framework for on-line anomaly detection that we propose. Second, since obtaining real smart meter data is difficult due to privacy issues, we present an algorithm for generating large realistic data sets from a small seed of real data. Third, we implement...

The enrichment secondary market

International Nuclear Information System (INIS)

Einbund, D.R.

1986-01-01

This paper will addresses two topics: the background to the present status of the enrichment secondary market and the future outlook of the secondary market in enrichment services, and the viability of the nuclear fuel brokerage industry. These two topics are inevitably connected, as most secondary market activity, not only in enrichment but also in natural uranium, has traditionally been conducted with the participation of brokers. Therefore, the author interrelates these topics

233U Assay A Neutron NDA System

Energy Technology Data Exchange (ETDEWEB)

Hensley, D.C.; Lucero, A.J.; Pierce, L.

1998-11-17

The assay of highly enriched {sup 233}U material presents some unique challenges. Techniques which apply to the assay of materials of Pu or enriched {sup 235}U do not convert easily over to the assay of {sup 233}U. A specialized neutron assay device is being fabricated to exploit the singles neutron signal, the weak correlated neutron signal, and an active correlated signal. These pieces of information when combined with {gamma} ray isotopics information should give a good overall determination of {sup 233}U material now stored in bldg. 3019 at the Oak Ridge National Laboratory.

Antioxidant activities of traditional plants in Sri Lanka by DPPH free radical-scavenging assay

Directory of Open Access Journals (Sweden)

Kotaro Hara

2018-04-01

Full Text Available This article describes free radical-scavenging activities of extracts of several plants harvested in Sri Lanka through the 1,1-diphenyl-2-picrylhydrazyl (DPPH assay. These plants have traditionally been used in the indigenous systems of medicine in Sri Lanka, such as Ayurveda, as described below. (English name, “local name in Sri Lanka,” (scientific name.bougainvillea plant, “bouganvilla,” (Bougainvillea grabla, purple fruited pea eggplant,”welthibbatu,” (Solanum trilobatum [1], country borage plant, “kapparawalliya,” (Plectranthus amboinicus [2], malabar nut plant, “adhatoda,” (Justicia adhatoda [3], long pepper plant,”thippili,” (Piper longum [4], holy basil plant, “maduruthala,” (Ocimum tenuiflorum [5], air plant, “akkapana,” (Kalanchoe pinnata [6], plumed cockscomb plant, “kiri-henda,” (Celosia argentea [7], neem plant,”kohomba,” (Azadirachta indica [8], balipoovu plant, “polpala,” (Aerva lanata [9], balloon-vine plant, “wel penera,” (Cardiospermum halicacabum [10], emblic myrobalan plant, “nelli,” (Phyllanthus emblica [11], indian copperleaf plant, “kuppameniya,” (Acalypha indica [12], spreading hogweed plant, “pita sudu sarana,” (Boerhavia diffusa [13], curry leaf plant, “karapincha,” (Murraya koenigii [14], indian pennywort plant, “gotukola,” (Centera asiatica [15], jewish plum plant, “ambarella,”(Spondias dulcis [16]. Keywords: Antioxidative activity, DPPH radical-scavenging assay, Traditional plant, Medical herb

Advanced Metering Infrastructure based on Smart Meters

Science.gov (United States)

Suzuki, Hiroshi

By specifically designating penetrations rates of advanced meters and communication technologies, devices and systems, this paper introduces that the penetration of advanced metering is important for the future development of electric power system infrastructure. It examines the state of the technology and the economical benefits of advanced metering. One result of the survey is that advanced metering currently has a penetration of about six percent of total installed electric meters in the United States. Applications to the infrastructure differ by type of organization. Being integrated with emerging communication technologies, smart meters enable several kinds of features such as, not only automatic meter reading but also distribution management control, outage management, remote switching, etc.

Conceptual design for the field test and evaluation of the gas-phase UF6 enrichment meter

International Nuclear Information System (INIS)

Strittmatter, R.B.; Leavitt, J.N.; Slice, R.W.

1980-12-01

An in-line enrichment monitor is being developed to provide real-time enrichment data for the gas-phase UF 6 feed stream of an enrichment plant. Data from proof-of-principle measurements using a laboratory prototype system are presented. A conceptual design for an enrichment monitor to be field tested and evaluated at the Oak Ridge Gaseous Diffusion Plant is reported

Enrichment Assay Methods Development for the Integrated Cylinder Verification System

Energy Technology Data Exchange (ETDEWEB)

Smith, Leon E.; Misner, Alex C.; Hatchell, Brian K.; Curtis, Michael M.

2009-10-22

International Atomic Energy Agency (IAEA) inspectors currently perform periodic inspections at uranium enrichment plants to verify UF6 cylinder enrichment declarations. Measurements are typically performed with handheld high-resolution sensors on a sampling of cylinders taken to be representative of the facility's entire product-cylinder inventory. Pacific Northwest National Laboratory (PNNL) is developing a concept to automate the verification of enrichment plant cylinders to enable 100 percent product-cylinder verification and potentially, mass-balance calculations on the facility as a whole (by also measuring feed and tails cylinders). The Integrated Cylinder Verification System (ICVS) could be located at key measurement points to positively identify each cylinder, measure its mass and enrichment, store the collected data in a secure database, and maintain continuity of knowledge on measured cylinders until IAEA inspector arrival. The three main objectives of this FY09 project are summarized here and described in more detail in the report: (1) Develop a preliminary design for a prototype NDA system, (2) Refine PNNL's MCNP models of the NDA system, and (3) Procure and test key pulse-processing components. Progress against these tasks to date, and next steps, are discussed.

Enrichment Assay Methods Development for the Integrated Cylinder Verification System

International Nuclear Information System (INIS)

Smith, Leon E.; Misner, Alex C.; Hatchell, Brian K.; Curtis, Michael M.

2009-01-01

International Atomic Energy Agency (IAEA) inspectors currently perform periodic inspections at uranium enrichment plants to verify UF6 cylinder enrichment declarations. Measurements are typically performed with handheld high-resolution sensors on a sampling of cylinders taken to be representative of the facility's entire product-cylinder inventory. Pacific Northwest National Laboratory (PNNL) is developing a concept to automate the verification of enrichment plant cylinders to enable 100 percent product-cylinder verification and potentially, mass-balance calculations on the facility as a whole (by also measuring feed and tails cylinders). The Integrated Cylinder Verification System (ICVS) could be located at key measurement points to positively identify each cylinder, measure its mass and enrichment, store the collected data in a secure database, and maintain continuity of knowledge on measured cylinders until IAEA inspector arrival. The three main objectives of this FY09 project are summarized here and described in more detail in the report: (1) Develop a preliminary design for a prototype NDA system, (2) Refine PNNL's MCNP models of the NDA system, and (3) Procure and test key pulse-processing components. Progress against these tasks to date, and next steps, are discussed.

Methods for nondestructive assay holdup measurements in shutdown uranium enrichment facilities

International Nuclear Information System (INIS)

Hagenauer, R.C.; Mayer, R.L. II.

1991-09-01

Measurement surveys of uranium holdup using nondestructive assay (NDA) techniques are being conducted for shutdown gaseous diffusion facilities at the Oak Ridge K-25 Site (formerly the Oak Ridge Gaseous Diffusion Plant). When in operation, these facilities processed UF 6 with enrichments ranging from 0.2 to 93 wt % 235 U. Following final shutdown of all process facilities, NDA surveys were initiated to provide process holdup data for the planning and implementation of decontamination and decommissioning activities. A three-step process is used to locate and quantify deposits: (1) high-resolution gamma-ray measurements are performed to generally define the relative abundances of radioisotopes present, (2) sizable deposits are identified using gamma-ray scanning methods, and (3) the deposits are quantified using neutron measurement methods. Following initial quantitative measurements, deposit sizes are calculated; high-resolution gamma-ray measurements are then performed on the items containing large deposits. The quantitative estimates for the large deposits are refined on the basis of these measurements. Facility management is using the results of the survey to support a variety of activities including isolation and removal of large deposits; performing health, safety, and environmental analyses; and improving facility nuclear material control and accountability records. 3 refs., 1 tab

Sixty-fold electrolytic batch enrichment for the assay of environmental tritium

International Nuclear Information System (INIS)

Gugelmann, A.A.; Brenninkmeijer, C.A.M.; Jalil, A.

1977-01-01

In Part 1 the general principles for the evaluation of low-level counting systems are outlined. Part 2 reviews current practices and experiences in tritium enrichment and counting systems. Part 3 describes a new approach to achieve high enrichment factors in a simple batch process. Sixty-fold tritium enrichment is achieved with an eighty-fold volume reduction. Specially designed large surface electrolysis cells are operated initially in series at 13A constant current, then for the final rundown at a constant voltage at 3.5V the cells are connected in parallel. (auth.)

New generation enrichment monitoring technology for gas centrifuge enrichment plants

International Nuclear Information System (INIS)

Ianakiev, Kiril D.; Alexandrov, Boian S.; Boyer, Brian D.; Hill, Thomas R.; Macarthur, Duncan W.; Marks, Thomas; Moss, Calvin E.; Sheppard, Gregory A.; Swinhoe, Martyn T.

2008-01-01

The continuous enrichment monitor, developed and fielded in the 1990s by the International Atomic Energy Agency, provided a go-no-go capability to distinguish between UF 6 containing low enriched (approximately 4% 235 U) and highly enriched (above 20% 235 U) uranium. This instrument used the 22-keV line from a 109 Cd source as a transmission source to achieve a high sensitivity to the UF 6 gas absorption. The 1.27-yr half-life required that the source be periodically replaced and the instrument recalibrated. The instrument's functionality and accuracy were limited by the fact that measured gas density and gas pressure were treated as confidential facility information. The modern safeguarding of a gas centrifuge enrichment plant producing low-enriched UF 6 product aims toward a more quantitative flow and enrichment monitoring concept that sets new standards for accuracy stability, and confidence. An instrument must be accurate enough to detect the diversion of a significant quantity of material, have virtually zero false alarms, and protect the operator's proprietary process information. We discuss a new concept for advanced gas enrichment assay measurement technology. This design concept eliminates the need for the periodic replacement of a radioactive source as well as the need for maintenance by experts. Some initial experimental results will be presented.

Privacy-Preserving Smart Metering with Authentication in a Smart Grid

Directory of Open Access Journals (Sweden)

Jun Beom Hur

2015-12-01

Full Text Available The traditional security objectives of smart grids have been availability, integrity, and confidentiality. However, as the grids incorporate smart metering and load management, user and corporate privacy is increasingly becoming an issue in smart grid networks. Although transmitting current power consumption levels to the supplier or utility from each smart meter at short intervals has an advantage for the electricity supplier’s planning and management purposes, it threatens user privacy by disclosing fine-grained consumption data and usage behavior to utility providers. In this study, we propose a distributed incremental data aggregation scheme where all smart meters on an aggregation path are involved in routing the data from the source meter to the collection unit. User privacy is preserved by symmetric homomorphic encryption, which allows smart meters to participate in the aggregation without seeing any intermediate or final result. Aggregated data is further integrated with an aggregate signature to achieve data integrity and smart meter authentication in such a way that dishonest or fake smart meters cannot falsify data en route. Only the collection unit can obtain the aggregated data and verify its integrity while the individual plain data are not exposed to the collection unit. Therefore, user privacy and security are improved for the smart metering in a smart grid network.

Performance Analysis of Secure and Private Billing Protocols for Smart Metering

Directory of Open Access Journals (Sweden)

Tom Eccles

2017-11-01

Full Text Available Traditional utility metering is to be replaced by smart metering. Smart metering enables fine-grained utility consumption measurements. These fine-grained measurements raise privacy concerns due to the lifestyle information which can be inferred from the precise time at which utilities were consumed. This paper outlines and compares two privacy-respecting time of use billing protocols for smart metering and investigates their performance on a variety of hardware. These protocols protect the privacy of customers by never transmitting the fine-grained utility readings outside of the customer’s home network. One protocol favors complexity on the trusted smart meter hardware while the other uses homomorphic commitments to offload computation to a third device. Both protocols are designed to operate on top of existing cryptographic secure channel protocols in place on smart meters. Proof of concept software implementations of these protocols have been written and their suitability for real world application to low-performance smart meter hardware is discussed. These protocols may also have application to other privacy conscious aggregation systems, such as electronic voting.

Metering Plan: Intelligent Operational Strategies Through Enhanced Metering Systems

Energy Technology Data Exchange (ETDEWEB)

Pope, Jason E.

2016-07-27

The Sustainability Program at Pacific Northwest National Laboratory (PNNL) has adopted a “triple-bottom-line” approach of environmental stewardship, social responsibility, and economic prosperity to its operations. Metering at PNNL works in support of all three, specifically to measure and inform building energy use and greenhouse gas emissions and minimize water use. The foundation for metering at PNNL is a core goal set, which consists of four objectives: providing accurate data without interruption, analyzing data while it is still new, providing actionable recommendations to operations management, and ensuring PNNL’s compliance with contract metering requirements. These core objectives guide the decisions that we make during annual planning and as we operate throughout the year. This 2016 edition of the Metering Plan conveys the metering practices for and vision of the Sustainability Program. Changes in this plan from the 2015 edition include updated tables and an enhanced discussion on energy tracking systems used at PNNL. This plan also discusses updated benchmarking strategies using PNNL’s graphics and analytics tool, BuildingOS by Lucid Design Group. This plan presents our progress toward the metering goals shared by all federal agencies and highlights our successful completion of metering requirements. Currently, PNNL is fully compliant with the applicable legislative and Executive Order metering requirements. PNNL’s approach to the installation of new meters will be discussed. Perhaps most importantly, this plan details the analysis techniques utilized at PNNL that rely on the endless streams of data newly available as a result of increased meter deployment over the last several years. Previous Metering Plans have documented specific meter connection schemes as PNNL focused on deploying meters in a first step toward managing energy and water use. This plan serves not only to highlight PNNL’s successful completion of agency metering goals, but

Use of L-Glutamic Acid in a New Enrichment Broth (R-TATP Broth) for Detecting the Presence or Absence of Molds in Raw Ingredients/Personal Care Product Formulations by Using an ATP Bioluminescence Assay.

Science.gov (United States)

Yang, Youjun; English, Donald J

The present study reports the effects of adding L-glutamic acid to a new enrichment broth designated as R-TATP broth, to promote the growth of slow-growing mold microorganisms such as Aspergillus brasiliensis and Aspergillus oryzae , without interfering in the growth of other types of microorganisms. This L-glutamic acid containing enrichment broth would be particularly valuable in a rapid microbial detection assay such as an adenosine triphosphate (ATP) bioluminescence assay. By using this new enrichment broth, the amount of ATP (represented as relative light unit ratio after normalized with the negative test control) from mold growth was significantly increased by reducing the time of detection of microbial contamination in a raw ingredient or personal care product formulation from an incubation period of 48-18 h. By using L-glutamic acid in this enrichment broth, the lag phase of the mold growth cycle was shortened. In response to various concentrations of L-glutamic acid in R-TATP broth, there was an increased amount of ATP that had been produced by mold metabolism in an ATP bioluminescence assay. By using L-glutamic acid in R-TATP broth in an ATP bioluminescence assay, the presence of mold could be detected in 18 h as well as other types of microorganisms that may or may not be present in a test sample. By detecting the presence or absence of microbial contamination in 18 h, it is superior in comparison to a 48-96 h incubation period by using either a standard or rapid detection method.

An Internal Standard for Assessing Phosphopeptide Recovery from Metal Ion/Oxide Enrichment Strategies

Science.gov (United States)

Paulo, Joao A.; Navarrete-Perea, Jose; Erickson, Alison R.; Knott, Jeffrey; Gygi, Steven P.

2018-04-01

Phosphorylation-mediated signaling pathways have major implications in cellular regulation and disease. However, proteins with roles in these pathways are frequently less abundant and phosphorylation is often sub-stoichiometric. As such, the efficient enrichment, and subsequent recovery of phosphorylated peptides, is vital. Mass spectrometry-based proteomics is a well-established approach for quantifying thousands of phosphorylation events in a single experiment. We designed a peptide internal standard-based assay directed toward sample preparation strategies for mass spectrometry analysis to understand better phosphopeptide recovery from enrichment strategies. We coupled mass-differential tandem mass tag (mTMT) reagents (specifically, TMTzero and TMTsuper-heavy), nine mass spectrometry-amenable phosphopeptides (phos9), and peak area measurements from extracted ion chromatograms to determine phosphopeptide recovery. We showcase this mTMT/phos9 recovery assay by evaluating three phosphopeptide enrichment workflows. Our assay provides data on the recovery of phosphopeptides, which complement other metrics, namely the number of identified phosphopeptides and enrichment specificity. Our mTMT/phos9 assay is applicable to any enrichment protocol in a typical experimental workflow irrespective of sample origin or labeling strategy. [Figure not available: see fulltext.

From Smart Metering to Smart Grid

Science.gov (United States)

Kukuča, Peter; Chrapčiak, Igor

2016-06-01

The paper deals with evaluation of measurements in electrical distribution systems aimed at better use of data provided by Smart Metering systems. The influence of individual components of apparent power on the power loss is calculated and results of measurements under real conditions are presented. The significance of difference between the traditional and the complex evaluation of the electricity consumption efficiency by means of different definitions of the power factor is illustrated.

Uranium enrichment plans and policies

International Nuclear Information System (INIS)

Schwennesen, J.L.

1981-01-01

Significant progress has been made in US efforts to expand its enrichment capacity. The Cascade Improvement Program (CIP) and Cascade Upgrading Program (CUP) are now complete at Oak Ridge and Paducah and almost complete at Portsmouth. Considerable progress has also been made in constructing the Gas Centrifuge Enrichment Plant (GCEP), and physical construction of the first process building is well under way. Current plans are to have two process buildings on-line by 1989 with the remaining six buildings to be added sequentially as needed to meet demand. The status of DOE enrichment services contracts is essentially unchanged from that reported at last year's seminar. The OUEA latest forecast of nuclear power growth, however, is considerably lower than reported last year, although a leveling trend is becoming apparent. The Variable Tails Assay Option (VTAO) of the AFC contract was made available for the third time for FY 1983. The DOE inventories of natural uranium still remain high. The Department of Energy will dispose of this material by using it for Government programs and for enrichment plant operations. It appears that Government inventories of uranium are adequate through at least the mid-1990s. It remains DOE policy not to dispose of its natural uranium stocks through direct sales in the marketplace, except for very small quantities or if an emergency situation would exist and all reasonable attempts had been made, without success, to obtain natural uranium from commercial sources. Finally, with regard to DOE plans on future transaction tails assays, it still appears likely that the current 0.20 percent uranium-235 reference tails assay will be maintained until well into the 1990s, at which time it might be increased up to 0.25 percent uranium-235

Privacy-Preserving Meter Report Protocol of Isolated Smart Grid Devices

Directory of Open Access Journals (Sweden)

Zhiwei Wang

2017-01-01

Full Text Available Smart grid aims to improve the reliability, efficiency, and security of the traditional grid, which allows two-way transmission and efficiency-driven response. However, a main concern of this new technique is that the fine-grained metering data may leak the personal privacy information of the customers. Thus, the data aggregation mechanism for privacy protection is required for the meter report protocol in smart grid. In this paper, we propose an efficient privacy-preserving meter report protocol for the isolated smart grid devices. Our protocol consists of an encryption scheme with additively homomorphic property and a linearly homomorphic signature scheme, where the linearly homomorphic signature scheme is suitable for privacy-preserving data aggregation. We also provide security analysis of our protocol in the context of some typical attacks in smart grid. The implementation of our protocol on the Intel Edison platform shows that our protocol is efficient enough for the physical constrained devices, like smart meters.

Active interrogation of highly enriched uranium

Science.gov (United States)

Fairrow, Nannette Lea

Safeguarding special nuclear material (SNM) in the Department of Energy Complex is vital to the national security of the United States. Active and passive nondestructive assays are used to confirm the presence of SNM in various configurations ranging from waste to nuclear weapons. Confirmation measurements for nuclear weapons are more challenging because the design complicates the detection of a distinct signal for highly enriched uranium. The emphasis of this dissertation was to investigate a new nondestructive assay technique that provides an independent and distinct signal to confirm the presence of highly enriched uranium (HEU). Once completed and tested this assay method could be applied to confirmation measurements of nuclear weapons. The new system uses a 14-MeV neutron source for interrogation and records the arrival time of neutrons between the pulses with a high efficiency detection system. The data is then analyzed by the Feynman reduced variance method. The analysis determined the amount of correlation in the data and provided a unique signature of correlated fission neutrons. Measurements of HEU spheres were conducted at Los Alamos with the new system. Then, Monte Carlo calculations were performed to verify hypothesis made about the behavior of the neutrons in the experiment. Comparisons of calculated counting rates by the Monte Carlo N-Particle Transport Code (MCNP) were made with the experimental data to confirm that the measured response reflected the desired behavior of neutron interactions in the highly enriched uranium. In addition, MCNP calculations of the delayed neutron build-up were compared with the measured data. Based on the results obtained from this dissertation, this measurement method has the potential to be expanded to include mass determinations of highly enriched uranium. Although many safeguards techniques exist for measuring special nuclear material, the number of assays that can be used to confirm HEU in shielded systems is

A glucose meter evaluation co-designed with both health professional and consumer input.

Science.gov (United States)

Thompson, Harmony; Chan, Huan; Logan, Florence J; Heenan, Helen F; Taylor, Lynne; Murray, Chris; Florkowski, Christopher M; Frampton, Christopher M A; Lunt, Helen

2013-11-22

Health consumer's input into assessment of medical device safety is traditionally given either as part of study outcome (trial participants) or during post marketing surveillance. Direct consumer input into the methodological design of device assessment is less common. We discuss the difference in requirements for assessment of a measuring device from the consumer and clinician perspectives, using the example of hand held glucose meters. Around 80,000 New Zealanders with diabetes recently changed their glucose meter system, to enable ongoing access to PHARMAC subsidised meters and strips. Consumers were most interested in a direct comparison of their 'old' meter system (Accu-Chek Performa) with their 'new' meter system (CareSens brand, including the CareSens N POP), rather than comparisons against a laboratory standard. This direct comparison of meter/strip systems showed that the CareSens N POP meter read around 0.6 mmol/L higher than the Performa system. Whilst this difference is unlikely to result in major errors in clinical decision making such as major insulin dosing errors, this information is nevertheless of interest to consumers who switched meters so that they could maintain access to PHARMAC subsidised meters and strips. We recommend that when practical, the consumer perspective be incorporated into study design related to medical device assessment.

Smart Metering. Technological, economic and legal aspects. 2. ed.; Smart Metering. Technologische, wirtschaftliche und juristische Aspekte des Smart Metering

Energy Technology Data Exchange (ETDEWEB)

Koehler-Schute, Christiana (ed.)

2010-07-01

Smart metering comprises more than just meter technology, and the use of information and communication technologies is indispensable. Processes, roles and business models must be reconsidered as further challenges arise in the context of smart metering. For one, there is the operator of the metering points. Secondly, there is the end user who is in the role of an active market partner. Further, there is smart metering as a basic technology, e.g. for smart grids and smart homes. In spite of the need for action, many utilities are reluctant to introduce smart metering. Reasons for this are the cost, a lack of defined standards, and an unclear legal situation. On the other hand, smart metering offers potential for grids and distribution that should be made use of. The authors discuss all aspects of the subject. The point out the chances and limitations of smart metering and present their own experience. [German] Smart Metering geht weit ueber die Zaehlertechnologie hinaus und der Einsatz von Informations- und Kommunikationstechnologien ist unabdingbar. Damit einhergehend muessen Prozesse, Rollen und auch Geschaeftsmodelle neu durchdacht werden. Denn weitere Herausforderungen stehen im direkten Zusammenhang mit Smart Metering. Das ist zum einen die Rolle des Messstellenbetreibers / Messdienstleisters. Das ist zum anderen der Endnutzer, dem die Rolle des aktiven Marktpartners zugedacht wird. Das ist des Weiteren das Smart Metering als Basistechnologie beispielsweise fuer Smart Grid und Smart Home. Trotz des Handlungsdrucks stehen viele Unternehmen der Energiewirtschaft dem Smart Metering zurueckhaltend gegenueber. Drei gewichtige Gruende werden ins Feld gefuehrt: die Kostenfrage, nicht definierte Standards und die in vielen Bereichen ungeklaerte Gesetzeslage. Demgegenueber bietet das Smart Metering Potenziale fuer Netz und Vertrieb, die es zu nutzen gilt. Die Autoren setzen sich in ihren Beitraegen mit diesen Themen auseinander, zeigen Chancen, aber auch Grenzen des

Changing characteristics of the TDx digoxin II assay in detecting bufadienolides in a traditional Chinese medicine: for better or worse?

Science.gov (United States)

Panesar, Nirmal S; Chan, Kam W; Law, Lap K

2005-10-01

In 1992, apparent digoxin concentrations determined by the Abbott TDx II assay 5 hours after the ingestion of 10 pills of traditional Chinese medicine containing toad secretions (chan su) by 7 volunteers, yielded results that were equimolar to bufalin measured by 2 in-house bufalin radioimmunoassays (RIAs). Recently, a 17-year-old Chinese female unintentionally took 100 (instead of 10) of these pills for a sore throat but suffered no ill effects. The blood bufalin concentration at 3 hours by 1 of the 2 RIAs was 10.93 nmol/L, which was commensurate with the dose. However, the apparent digoxin measured by a TDx II assay produced in 2004 was only 3.08 nmol/L, which probably reflects the change in the specificity of the polyclonal digoxin antisera used in the assay over the years. In 1989, the TDx assay was commended for its ability to detect poisoning from plant and animal cardenolides, a property that seems to be waning and, thus, bad news for those wishing to use the assay to detect alternative cardenolides. But, on the other hand, it possibly eliminates the "specter" of digoxin-like immunoreactive substance (DLIS) that has afflicted some digoxin assays, which can only be good news.

Requirements for Pseudomonas aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay.

Science.gov (United States)

Heussler, Gary E; Miller, Jon L; Price, Courtney E; Collins, Alan J; O'Toole, George A

2016-11-15

CRISPR (clustered regularly interspaced short palindromic repeat)-Cas (CRISPR-associated protein) systems are diverse and found in many archaea and bacteria. These systems have mainly been characterized as adaptive immune systems able to protect against invading mobile genetic elements, including viruses. The first step in this protection is acquisition of spacer sequences from the invader DNA and incorporation of those sequences into the CRISPR array, termed CRISPR adaptation. Progress in understanding the mechanisms and requirements of CRISPR adaptation has largely been accomplished using overexpression of cas genes or plasmid loss assays; little work has focused on endogenous CRISPR-acquired immunity from viral predation. Here, we developed a new biofilm-based assay system to enrich for Pseudomonas aeruginosa strains with new spacer acquisition. We used this assay to demonstrate that P. aeruginosa rapidly acquires spacers protective against DMS3vir, an engineered lytic variant of the Mu-like bacteriophage DMS3, through primed CRISPR adaptation from spacers present in the native CRISPR2 array. We found that for the P. aeruginosa type I-F system, the cas1 gene is required for CRISPR adaptation, recG contributes to (but is not required for) primed CRISPR adaptation, recD is dispensable for primed CRISPR adaptation, and finally, the ability of a putative priming spacer to prime can vary considerably depending on the specific sequences of the spacer. Our understanding of CRISPR adaptation has expanded largely through experiments in type I CRISPR systems using plasmid loss assays, mutants of Escherichia coli, or cas1-cas2 overexpression systems, but there has been little focus on studying the adaptation of endogenous systems protecting against a lytic bacteriophage. Here we describe a biofilm system that allows P. aeruginosa to rapidly gain spacers protective against a lytic bacteriophage. This approach has allowed us to probe the requirements for CRISPR adaptation in

Application of the MGAU code for measuring 235U enrichment at the Brazilian Safeguards Laboratory

International Nuclear Information System (INIS)

Grund, Marcos S.; Dias, Fabio C.

2009-01-01

MGAU is a software tool for conducting uranium enrichment measurements based on high-resolution gamma ray spectroscopy. The code is capable of analyzing spectra (90 - 120 KeV region) collected from a wide variety of sample geometries and compositions. The main advantage of the code is its ability to perform spectra evaluation without a requirement for calibration with representative standards. However, it does require that the daughter isotopes be in activity equilibrium with the 235 U and 238 U parent isotopes. In order for the code to be more versatile in overcoming its limitations, a modified version of the traditional 'enrichment meter' method has been also added. In order to perform confirmatory uranium enrichment measurements for safeguards purposes at a laboratory environment, the Brazilian Safeguards Laboratory is investigating the performance of a nondestructive technique based on the use of the MGAU code for analyzing of gamma-ray spectra collected from pure uranium samples (primarily natural and low enriched powders and pellets). Several new good practice procedures were implemented in order to optimize the performance of the method at the best achievable level. This includes positioning of both the high-purity germanium detector and the sample inside a lead chamber for reducing background influence, collection of replicate measurements, and application of robust statistical treatment of data to reduce random contributions from counting statistics to the final uncertainty. Also, temperature and humidity inside the laboratory were monitored so that significant influences in results could be observed. Based on the results arising from analysis of certified reference materials, this paper discusses the performance of the MGAU code version 4.0 with focus on the uncertainties related to sample-dependent effects (mass, density, matrix composition and enrichment level). The reliability of the MGAU predicted uncertainty for single measurements and the occurrence

BH3105 type neutron dose equivalent meter of high sensitivity

International Nuclear Information System (INIS)

Ji Changsong; Zhang Enshan; Yang Jianfeng; Zhang Hong; Huang Jiling

1995-10-01

It is noted that to design a neutron dose meter of high sensitivity is almost impossible in the frame of traditional designing principle--'absorption net principle'. Based on a newly proposed principle of obtaining neutron dose equi-biological effect adjustment--' absorption stick principle', a brand-new neutron dose-equivalent meter with high neutron sensitivity BH3105 has been developed. Its sensitivity reaches 10 cps/(μSv·h -1 ), which is 18∼40 times higher than one of foreign products of the same kind and is 10 4 times higher than that of domestic FJ342 neutron rem-meter. BH3105 has a measurement range from 0.1μSv/h to 1 Sv/h which is 1 or 2 orders wider than that of the other's. It has the advanced properties of gamma-resistance, energy response, orientation, etc. (6 tabs., 5 figs.)

Using smart meter to monitor the energy consumption of home appliances

International Nuclear Information System (INIS)

Dong, M.; Xu, W.

2010-01-01

A smart meter provides the foundation for the smart grid, which represent the future electric system in terms of communications, sensors and automation to improve the flexibility, reliability and efficiency of power systems. Smart meters are installed at the utility-customer interface point to provide real-time power usage and price data to each electricity user. The purpose is to create customer awareness on electricity consumption and help users to conserve energy. Smart meters are being deployed throughout North America to replace most traditional meters. However, this paper discussed a major technical gap of the smart meter. Existing smart meters do not provide households with enough feedback needed to achieve effective energy saving. In order to support the energy conservation effort of a customer, the whole house energy data must be displayed on minute or second basis, and it must also be broken down into individual appliance levels. The data of an appliance's energy usage is the most useful information for users to modify their actions and conserve energy. This paper proposed to make the smart meter capable of reporting the overall consumption of a household, as well as monitoring how individual appliances use electricity. It presented a method on using different appliance signatures to identify appliances and make energy estimations on their respective consumptions. Paired with time-of-use or other real time pricing mechanisms, the method enables customers to save energy. This paper also demonstrated how to implement an algorithm on the smart meter platform. Future work will focus on making the algorithm more accurate and faster, and on integrating the smart meter with an appliance energy monitoring system. 21 refs., 6 tabs., 3 figs.

Adoption of Enriched Local Complementary Food in Osun State ...

African Journals Online (AJOL)

Locally processed complementary foods, appropriately enriched can complement breast milk and traditional foods during the nutritionally vulnerable periods of a child life. The study therefore examines the adoption of enriched local complementary foods in Osun State Nigeria. Structured interview schedule was used to ...

NUCLEAR MIXING METERS FOR CLASSICAL NOVAE

Energy Technology Data Exchange (ETDEWEB)

Kelly, Keegan J.; Iliadis, Christian; Downen, Lori; Champagne, Art [Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255 (United States); José, Jordi [Departament de Física i Enginyeria Nuclear, EUETIB, Universitat Politècnica de Catalunya, E-08036 Barcelona (Spain)

2013-11-10

Classical novae are caused by mass transfer episodes from a main-sequence star onto a white dwarf via Roche lobe overflow. This material possesses angular momentum and forms an accretion disk around the white dwarf. Ultimately, a fraction of this material spirals in and piles up on the white dwarf surface under electron-degenerate conditions. The subsequently occurring thermonuclear runaway reaches hundreds of megakelvin and explosively ejects matter into the interstellar medium. The exact peak temperature strongly depends on the underlying white dwarf mass, the accreted mass and metallicity, and the initial white dwarf luminosity. Observations of elemental abundance enrichments in these classical nova events imply that the ejected matter consists not only of processed solar material from the main-sequence partner but also of material from the outer layers of the underlying white dwarf. This indicates that white dwarf and accreted matter mix prior to the thermonuclear runaway. The processes by which this mixing occurs require further investigation to be understood. In this work, we analyze elemental abundances ejected from hydrodynamic nova models in search of elemental abundance ratios that are useful indicators of the total amount of mixing. We identify the abundance ratios ΣCNO/H, Ne/H, Mg/H, Al/H, and Si/H as useful mixing meters in ONe novae. The impact of thermonuclear reaction rate uncertainties on the mixing meters is investigated using Monte Carlo post-processing network calculations with temperature-density evolutions of all mass zones computed by the hydrodynamic models. We find that the current uncertainties in the {sup 30}P(p, γ){sup 31}S rate influence the Si/H abundance ratio, but overall the mixing meters found here are robust against nuclear physics uncertainties. A comparison of our results with observations of ONe novae provides strong constraints for classical nova models.

Enrichment behavior and transport mechanism of soil-bound PAHs during rainfall-runoff events

International Nuclear Information System (INIS)

Zheng Yi; Luo Xiaolin; Zhang Wei; Wu Bin; Han Feng; Lin Zhongrong; Wang Xuejun

2012-01-01

Polycyclic Aromatic Hydrocarbons (PAHs) transported by surface runoff result in nonpoint source pollution and jeopardize aquatic ecosystems. The transport mechanism of PAHs during rainfall-runoff events has been rarely studied regarding pervious areas. An experimental system was setup to simulate the runoff pollution process on PAHs-contaminated soil. The enrichment behavior of soil-bound PAHs was investigated. The results show that soil organic matters (SOM), rather than clay particles, seem to be the main carrier of PAHs. The enrichment is highly conditioned on runoff and erosion processes, and its magnitude varies among PAH compounds. It is not feasible to build a simple and universal relationship between enrichment ratio and sediment discharge following the traditional enrichment theory. To estimate the flux of PAHs from pervious areas, soil erosion process has to be clearly understood, and both organic carbon content and composition of SOM should be factored into the calculation. - Highlights: ► Significant enrichment of particle-bound PAHs during rainfall-runoff events. ► Organic matters as the direct carrier of PAHs in runoff from contaminated soil. ► The traditional enrichment theory is not fully valid for PAHs. - The traditional enrichment theory is not fully valid for PAHs, and soil organic matters have a significant impact on the transport of PAHs during rainfall-runoff events.

Aesthetic and emotional effects of meter and rhyme in poetry.

Science.gov (United States)

Obermeier, Christian; Menninghaus, Winfried; von Koppenfels, Martin; Raettig, Tim; Schmidt-Kassow, Maren; Otterbein, Sascha; Kotz, Sonja A

2013-01-01

Metrical patterning and rhyme are frequently employed in poetry but also in infant-directed speech, play, rites, and festive events. Drawing on four line-stanzas from nineteenth and twentieth German poetry that feature end rhyme and regular meter, the present study tested the hypothesis that meter and rhyme have an impact on aesthetic liking, emotional involvement, and affective valence attributions. Hypotheses that postulate such effects have been advocated ever since ancient rhetoric and poetics, yet they have barely been empirically tested. More recently, in the field of cognitive poetics, these traditional assumptions have been readopted into a general cognitive framework. In the present experiment, we tested the influence of meter and rhyme as well as their interaction with lexicality in the aesthetic and emotional perception of poetry. Participants listened to stanzas that were systematically modified with regard to meter and rhyme and rated them. Both rhyme and regular meter led to enhanced aesthetic appreciation, higher intensity in processing, and more positively perceived and felt emotions, with the latter finding being mediated by lexicality. Together these findings clearly show that both features significantly contribute to the aesthetic and emotional perception of poetry and thus confirm assumptions about their impact put forward by cognitive poetics. The present results are explained within the theoretical framework of cognitive fluency, which links structural features of poetry with aesthetic and emotional appraisal.

Alteration in Business Models of Electricity Distribution Companies - A Case of Smart Metering

Energy Technology Data Exchange (ETDEWEB)

Trygg, P.

2013-09-01

Smart metering is currently implemented in many countries. The change from traditional metering is significant and impacts many of the Distribution system operator's (DSO's) activities. This dissertation aims to provide a structured model for analysing the impacts of Smart metering on a DSO's business. Research was conducted by gathering a theoretical framework for understanding how the business operates. The concept of business model has been presented. It is used as a framework of metering business. Detailed studies on specific parts of the business model have been carried out. These concentrate on finding a theoretical background of what Smart metering can provide. Cost analyses were conducted to better understand resources required by Smart metering. Problems related to ICT resources have also been studied based on the DSO's experiences. Partner network was studied based on DSO's experiences related to service purchasing and finally experiences in working with IT services provided to the DSOs has been presented. This dissertation presents a development trend that has taken place regarding Smart metering in implementation and operation. Results are presented in a business model framework to provide a more structured view on issues related to Smart metering. Also non-technical issues should be analysed to fully understand the extent of the changes taking place when implementing Smart metering. The information presented can be utilized when significant change factors to the DSO's business models can be recognized. (orig.)

Study on Differentiation Management of Grid Energy Metering Device under High Permeability by Distributed Energy and Smart Grid Technology

Science.gov (United States)

Wang, Haiyuan; Huang, Rui; Yang, Maotao; Chen, Hao

2017-12-01

At present, the electric energy metering device is classified according to the amount of electric energy and the degree of importance of the measurement object. The measuring device is also selected according to the characteristics of the traditional metering object.With the continuous development of smart grid, the diversification of measurement objects increasingly appear, the traditional measurement object classification has been unable to meet the new measurement object of personalized, differentiated needs.Withal, this paper constructs the subdivision model based on the object feature-system evaluation, classifies according to the characteristics of the measurement object, and carries on the empirical analysis with some kind of measurement object as the research object.The results show that the model works well and can be used to subdivide the metrological objects into different customer groups, which can be reasonably configured and managed for the metering devices. The research of this paper has effectively improved the economy and rationality of the energy metering device management, and improved the working efficiency.

Analysis of Flavonoids in Lotus (Nelumbo nucifera Leaves and Their Antioxidant Activity Using Macroporous Resin Chromatography Coupled with LC-MS/MS and Antioxidant Biochemical Assays

Directory of Open Access Journals (Sweden)

Ming-Zhi Zhu

2015-06-01

Full Text Available Lotus (Nelumbo nucifera leaves, a traditional Chinese medicinal herb, are rich in flavonoids. In an effort to thoroughly analyze their flavonoid components, macroporous resin chromatography coupled with HPLC-MS/MS was employed to simultaneously enrich and identify flavonoids from lotus leaves. Flavonoids extracted from lotus leaves were selectively enriched in the macroporous resin column, eluted subsequently as fraction II, and successively subjected to analysis with the HPLC-MS/MS and bioactivity assays. Altogether, fourteen flavonoids were identified, four of which were identified from lotus leaves for the first time, including quercetin 3-O-rhamnopyranosyl-(1→2-glucopyranoside, quercetin 3-O-arabinoside, diosmetin 7-O-hexose, and isorhamnetin 3-O-arabino- pyranosyl-(1→2-glucopyranoside. Further bioactivity assays revealed that these flavonoids from lotus leaves possess strong antioxidant activity, and demonstrate very good potential to be explored as food supplements or even pharmaceutical products to improve human health.

Forecasting Uncertainty in Electricity Smart Meter Data by Boosting Additive Quantile Regression

KAUST Repository

Taieb, Souhaib Ben

2016-03-02

Smart electricity meters are currently deployed in millions of households to collect detailed individual electricity consumption data. Compared with traditional electricity data based on aggregated consumption, smart meter data are much more volatile and less predictable. There is a need within the energy industry for probabilistic forecasts of household electricity consumption to quantify the uncertainty of future electricity demand in order to undertake appropriate planning of generation and distribution. We propose to estimate an additive quantile regression model for a set of quantiles of the future distribution using a boosting procedure. By doing so, we can benefit from flexible and interpretable models, which include an automatic variable selection. We compare our approach with three benchmark methods on both aggregated and disaggregated scales using a smart meter data set collected from 3639 households in Ireland at 30-min intervals over a period of 1.5 years. The empirical results demonstrate that our approach based on quantile regression provides better forecast accuracy for disaggregated demand, while the traditional approach based on a normality assumption (possibly after an appropriate Box-Cox transformation) is a better approximation for aggregated demand. These results are particularly useful since more energy data will become available at the disaggregated level in the future.

77 FR 40586 - Draft NIST Interagency Report (NISTIR) 7823, Advanced Metering Infrastructure Smart Meter...

Science.gov (United States)

2012-07-10

...-01] Draft NIST Interagency Report (NISTIR) 7823, Advanced Metering Infrastructure Smart Meter... Technology (NIST) seeks comments on Draft NISTIR 7823, Advanced Metering Infrastructure Smart Meter... conformance test requirements for the firmware upgradeability process for the Advanced Metering Infrastructure...

Environmental enrichment and exercise are better than social enrichment to reduce memory deficits in amyloid beta neurotoxicity.

Science.gov (United States)

Prado Lima, Mariza G; Schimidt, Helen L; Garcia, Alexandre; Daré, Letícia R; Carpes, Felipe P; Izquierdo, Ivan; Mello-Carpes, Pâmela B

2018-03-06

Recently, nongenetic animal models to study the onset and development of Alzheimer's disease (AD) have appeared, such as the intrahippocampal infusion of peptides present in Alzheimer amyloid plaques [i.e., amyloid-β (Aβ)]. Nonpharmacological approaches to AD treatment also have been advanced recently, which involve combinations of behavioral interventions whose specific effects are often difficult to determine. Here we isolate the neuroprotective effects of three of these interventions-environmental enrichment (EE), anaerobic physical exercise (AnPE), and social enrichment (SE)-on Aβ-induced oxidative stress and on impairments in learning and memory induced by Aβ. Wistar rats were submitted to 8 wk of EE, AnPE, or SE, followed by Aβ infusion in the dorsal hippocampus. Short-term memory (STM) and long-term memory (LTM) of object recognition (OR) and social recognition (SR) were evaluated. Biochemical assays determined hippocampal oxidative status: reactive oxygen species, lipid peroxidation by thiobarbituric acid reactive substance (TBARS) test, and total antioxidant capacity by ferric reducing/antioxidant power (FRAP), as well as acetylcholinesterase activity. Aβ infusion resulted in memory deficits and hippocampal oxidative damage. EE and AnPE prevented all memory deficits (STM and LTM of OR and SR) and lipid peroxidation (i.e., TBARS). SE prevented only the SR memory deficits and the decrease of total antioxidant capacity decrease (i.e., FRAP). Traditionally, findings obtained with EE protocols do not allow discrimination of the roles of the three individual factors involved. Here we demonstrate that EE and physical exercise have better neuroprotective effects than SE in memory deficits related to Aβ neurotoxicity in the AD model tested.

Smart meters. Smart metering. A solution module for a future-oriented energy system; Intelligente Zaehler. Smart Metering. Ein Loesungsbaustein fuer ein zukunftsfaehiges Energiesystem

Energy Technology Data Exchange (ETDEWEB)

Grimm, Nadia; Seidl, Hans [comps.

2011-12-15

The German Energy Agency GmbH (Berlin, Federal Republic of Germany) reports on smart metering as a solution module for a future-oriented energy system by means of the following contributions: (1) Key role for smart meters; (2) What is smart metering? (3) Implementation of smart metering in Europe; (4) The market development to date in Germany; (5) Practical experiences with smart metering in Germany; (6) Frequently asked questions; (7) Smart metering in intelligent networks; (8) Legal framework conditions; (9) Data security and data protection in the utilisation of smart meters; (10) Ongoing information; (11) Efficient energy systems.

Portable wireless metering

Energy Technology Data Exchange (ETDEWEB)

DiPaola, L

1996-12-31

Electric utilities often face situations where conventional distribution station billing meters have been removed from service. This paper presents an innovative alternative to traditional solutions to the temporary billing situation such as the use of clamp-on devices called electronic recording ammeters. It examines how Ontario Hydro is measuring current, voltage, and power factor at a distribution station to calculate kilowatts and kVAR using an easy-to-install product that communicates its live readings directly to an existing billing system. The devices used for the measurements can be easily attached to a power line with a hotstick and contain a special core which senses current flow and powers appropriate electronics, which digitizes voltage and current data and transmits it via low-power FM radio for subsequent data storage and processing. The paper includes results of field trials and outlines the advantages of using the device.

Investigation and Comparison of Separate Meter-In Separate Meter-Out Control Strategies

DEFF Research Database (Denmark)

Pedersen, Henrik C.; Andersen, Torben Ole; Skoubo, Tobias

2014-01-01

In the later years, there has been an increased focus on new valve types, which yield the possibility to do Separate Meter-In Separate Meter-Out (SMISMO) control. This includes both digital valves, but proportional valves with separate metering spools and build in pressure sensors are also emerging....... The possibility to independently control the meter-in and meter-out side not only increase the functionality of the system, but also opens up for better performance and/or lowered energy consumption. The focus of the current paper is therefore on investigation and comparison of what may be obtained using...

Beyond revenue metering -- a new age for automatic meter reading

Energy Technology Data Exchange (ETDEWEB)

Chebra, R. J. [RJC Consulting L.L.C., PQ (Canada)

2002-10-01

Advanced metering, data management, and communications possibilities of automated meter reading are explored. Applications in the area of demand side management, including load reduction, peak shaving and load shifting, new tariff structures based on the 'time of use incentive/penalty' approach, and information grade metering are emphasized. Based on trends and expectations, it is predicted that AMR will continue to experience rapid growth and deployment as new services are made available to the mass market. For example, technological advances will enable the industry to make 'time of use metering ' more attractive and beneficial to residential consumers, and embedded intelligence will make it possible to achieve more holistic energy environments.

Capability of the electromagnetic isotope-enrichment facility at ORNL

International Nuclear Information System (INIS)

Newman, E.

1982-01-01

The isotope separation program at Oak Ridge National Laboratory (ORNL) prepares and distributes electromagnetically enriched stable isotopes to the worldwide scientific community. Among the topics discussed in the present paper are the methods of enriching isotopes, the limitations that apply to the quantity and final assay of the separation products, and a generalized production flowsheet indicating the capability of the facility. A brief description of each of the production steps, from the selection and preparation of initial feedstock to the recovery and distribution of the isotopically enriched material, is presented. The future of the facility, the continued supply of enriched isotopes, and the response of the program to new and changing requirements are emphasized

Assessment of the implementation regulations for smart meters; Beoordeling uitvoeringsregelingen Slimme Meter

Energy Technology Data Exchange (ETDEWEB)

Boekema, J.

2011-03-15

TNO (Netherlands) assessed whether the smart meter is reliable and future proof. By request of the Dutch Ministry of Economic Affairs, Agriculture and Innovation (ELI) an assessment was conducted of the requirements for smart meters and, as formulated in the Order in Council 'Decree on remotely readable metering devices', based on 48 tests regarding security, privacy and future stability. Taking into account a number of described recommendations, TNO deems the legislation and implementation schemes sufficient to allow for safe, reliable and future proof implementation of smart meters in the Netherlands. [Dutch] TNO heeft beoordeeld of de slimme meter betrouwbaar en toekomstvast is. Ten behoeve van het ministerie van Economische Zaken, Landbouw en Innovatie (ELI) zijn de eisen die aan slimme meters worden gesteld, en zoals verwoord in de AmvB 'Besluit op afstand uitleesbare meetinrichtingen', beoordeeld aan de hand van 48 toetsen over zekerheid (security), persoonlijke levenssfeer (privacy) en toekomstvastheid. Met inachtneming van een aantal omschreven aanbevelingen, vindt TNO wetgeving en uitvoeringsregelingen zodanig dat daarmee een veilige, betrouwbare en toekomstvaste slimme meter geimplementeerd kan worden in Nederland.

Exploring the energy benefits of advanced water metering

Energy Technology Data Exchange (ETDEWEB)

Berger, Michael A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hans, Liesel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Piscopo, Kate [Univ. of California, Berkeley, CA (United States); Sohn, Michael D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

2016-08-01

, due to structural economic and regulatory barriers. In California, we see examples of deployed advanced metering systems with demonstrated embedded energy savings through water conservation and leak detection. Finally, we also see substantial untapped opportunity in the agricultural sector for enabling electric demand response for both traditional peak shaving and more complex flexible and ancillary services through improved water tracking and farm automation.

Design and Realization of a Condition Management System for the Gateway Electrical Energy Metering Device

Directory of Open Access Journals (Sweden)

Chao Tang

2013-12-01

Full Text Available With the construction of firm and intelligent power grid in China, it is difficult for the traditional management method of electrical energy metering device to meet the prospecting requirements. Using the computer and internet techniques to realize the information and intelligentization of the electrical energy metering management has become a necessary guarantee of improving power supply ability, marketing control, and customer service. This paper introduced a kind of large and intelligent condition management system of the gateway electrical energy metering device. The key technologies and realize process were analyzed. Moreover, a detailed description of the application modules such as the GIS smart display of metering point, the condition management of metering devices and the visual monitoring of metering point was presented. The trial operation in the selected transformer substations and the power stations of Chongqing Power Electrical Corp. indicated that, the condition management system is very open, safety and efficient. According to the data exchange with the production and scheduling platform, the system improved the efficient operation of the electrical energy metering devices. Meanwhile, combined with the real-time visual monitoring, the condition management system improved the prevention ability of electricity filching, realized the unified automatic large-scale management of electrical energy metering devices.

Monitoring the enrichment of the UF6 in the pipework of a gas centrifuge enrichment plant

International Nuclear Information System (INIS)

Packer, T.W.; Close, D.A.; Pratt, J.C.

1987-01-01

Research in the UK and the US has resulted in the development of a nondestructive assay instrument which can confirm the presence of low enriched uranium, on a rapid Go, No-Go basis, in cascade header pipework in the centrifuge enrichment plant at Capenhurst. The instrument is based on gamma-ray spectrometry and x-ray fluorescence analysis. It allows pipes, 120mm outer diameter, to be inspected in a total measurement time of approximately 30 minutes. This paper describes the techniques developed and includes the results obtained during a demonstration to, and preliminary in-plant measurements by, members of the IAEA and EURATOM Inspectorates at Capenhurst

Portable wireless metering

Energy Technology Data Exchange (ETDEWEB)

DiPaola, L [Powtel Monitoring Systems, Inc., Ajax, ON (Canada)

1996-12-31

Portable meters were discussed as alternatives to standard billing meters for temporary installations. Current, voltage and power factor at a distribution station were measured to calculate kW and kVAR, using an easy to install product that communicates live readings directly to the existing billing system. A background of situations where temporary metering is a possible alternative to regular meters was presented. Use of electronic, clamp on Electronic Recording Ammeters (ERA) and their drawbacks were discussed. An improved temporary metering solution using FM radio transmission to deliver live data to a receiving device, the Eagle Series 3500, was introduced. Improvements over previous ERA systems were discussed, including accuracy, lack of batteries, immediate confirmation of functionality, current, voltage and power factor monitoring, direct feed to billing system, line crew savings, need for only a single unit at any given site, bi-directional power flow metering, independent report storage media, and a portable voltage and P.F. diagnostic tool. Details of trial applications at the Utopia distribution station west of Barrie, ON were presented. This technology was said to be still in the testing stage, but its flexibility and economy were sonsidered to be very promising for future application.

Smart metering. Conformance tests for electricity meters; Smart Metering. Konformitaetstests an Stromzaehlern

Energy Technology Data Exchange (ETDEWEB)

Bormann, Matthias; Pongratz, Siegfried [VDE Pruef- und Zertifizierungsinstitut, Offenbach (Germany)

2012-07-01

Introduction of communication technologies into today's energy network enables the interworking between the domains of smart metering, smart grid, smart home and e-mobility as well as the creation and provisioning of new innovative services such as efficient load adjustment. Due to this convergence the new energy networks are becoming increasingly complex. Ensuring the interworking between all network elements (e.g. electricity meters, gateways) in these smart energy networks is of utmost importance. To this end conformance and interoperability tests have to be defined to ensure that services work as expected. (orig.)

Micro-gen metering solutions

Energy Technology Data Exchange (ETDEWEB)

Elland, J.; Dickson, J.; Cranfield, P.

2003-07-01

This report summarises the results of a project to investigate the regulation of domestic electricity metering work and identify the most economic options for micro-generator installers to undertake work on electricity meters. A micro-generation unit is defined as an energy conversion system converting non-electrical energy into electrical energy and can include technologies such as photovoltaic systems, small-scale wind turbines, micro-hydroelectric systems, and combined heat and power systems. Details of six tasks are given and cover examination of the existing framework and legal documentation for metering work, the existing technical requirements for meter operators, meter operator personnel accreditation, appraisal of options for meter changes and for micro-generation installation, document change procedures, industry consultation, and a review of the costs implications of the options.

Analysis of copper-nickel ores by gamma-gamma method in ore enrichment works

International Nuclear Information System (INIS)

Bol'shakov, A.Yu.; Tovstenko, Yu.G.; Chinskij, E.B.; Eliseev, G.I.

1973-01-01

The paper presents experimental data on continuous gamma-gamma assay of copper-nickel ores on conveyor belts and of dry discrete samples of classifier overflow at the enrichment plants of the Pechenganikel' group. The relative errors are given of the results of comparison of two-hour rapid analyses and shift and 24-hour chemical analyses of classifier overflow samples with the figures for gamma-gamma assay. The factors affecting the accuracy of the latter technique are elucidated. Practical recommendations are given on the use of this technique at the above enrichment plants. (author)

Use of a real time PCR assay for detection of the ctxA gene of Vibrio cholerae in an environmental survey of Mobile Bay.

Science.gov (United States)

Blackstone, George M; Nordstrom, Jessica L; Bowen, Michael D; Meyer, Richard F; Imbro, Paula; DePaola, Angelo

2007-02-01

Toxigenic Vibrio cholerae, the etiological agent of cholera, is a natural inhabitant of the marine environment and causes severe diarrheal disease affecting thousands of people each year in developing countries. It is the subject of extensive testing of shrimp produced and exported from these countries. We report the development of a real time PCR (qPCR) assay to detect the gene encoding cholera toxin, ctxA, found in toxigenic V. cholerae strains. This assay was tested against DNA isolated from soil samples collected from diverse locations in the US, a panel of eukaryotic DNA from various sources, and prokaryotic DNA from closely related and unrelated bacterial sources. Only Vibrio strains known to contain ctxA generated a fluorescent signal with the 5' nuclease probe targeting the ctxA gene, thus confirming the specificity of the assay. In addition, the assay was quantitative in pure culture across a six-log dynamic range down to <10 CFU per reaction. To test the robustness of this assay, oysters, aquatic sediments, and seawaters from Mobile Bay, AL, were analyzed by qPCR and traditional culture methods. The assay was applied to overnight alkaline peptone water enrichments of these matrices after boiling the enrichments for 10 min. Toxigenic V. cholerae strains were not detected by either qPCR or conventional methods in the 16 environmental samples examined. A novel exogenous internal amplification control developed by us to prevent false negatives identified the samples that were inhibitory to the PCR. This assay, with the incorporated internal control, provides a highly specific, sensitive, and rapid detection method for the detection of toxigenic strains of V. cholerae.

Evaluation of a multi-marker immunomagnetic enrichment assay for the quantification of circulating melanoma cells

Directory of Open Access Journals (Sweden)

Freeman James B

2012-09-01

Full Text Available Abstract Background Circulating melanoma cells (CMCs are thought to be valuable in improving measures of prognosis in melanoma patients and may be a useful marker of residual disease to identify non-metastatic patients requiring adjuvant therapy. We investigated whether immunomagnetic enrichment targeting multiple markers allows more efficient enrichment of CMCs from patient peripheral blood than targeting a single marker. Furthermore, we aimed to determine whether the number of CMCs in patient blood was associated with disease stage. Methods We captured CMCs by targeting the melanoma associated markers MCSP and MCAM as well as the melanoma stem cell markers ABCB5 and CD271, both individually and in combination, by immunomagnetic enrichment. CMCs were enriched and quantified from the peripheral blood of 10 non-metastatic and 13 metastatic melanoma patients. Results Targeting all markers in combination resulted in the enrichment of more CMCs than when any individual marker was targeted (p  Conclusions Our results demonstrated that a combination of markers should be targeted for optimal isolation of CMCs. In addition, there are significantly more CMCs in metastatic patients compared with non-metastatic patients and therefore quantification of CMCs may prove to be a useful marker of disease progression.

Aptamer based peptide enrichment for quantitative analysis of gonadotropin-releasing hormone by LC-MS/MS.

Science.gov (United States)

Richards, S L; Cawley, A T; Cavicchioli, R; Suann, C J; Pickford, R; Raftery, M J

2016-04-01

Over recent years threats to racing have expanded to include naturally occurring biological molecules, such as peptides and proteins, and their synthetic analogues. Traditionally, antibodies have been used to enable detection of these compounds as they allow purification and concentration of the analyte of interest. The rapid expansion of peptide-based therapeutics necessitates a similarly rapid development of suitable antibodies or other means of enrichment. Potential alternative enrichment strategies include the use of aptamers, which offer the significant advantage of chemical synthesis once the nucleic acid sequence is known. A method was developed for the enrichment, detection and quantitation of gonadotropin-releasing hormone (GnRH) in equine urine using aptamer-based enrichment and LC-MS/MS. The method achieved comparable limits of detection (1 pg/mL) and quantification (2.5 pg/mL) to previously published antibody-based enrichment methods. The intra- and inter-assay precision achieved was less than 10% at both 5 and 20 pg/mL, and displayed a working dynamic range of 2.5-100 pg/mL. Significant matrix enhancement (170 ± 8%) and low analytical recovery (29 ± 15%) was observed, although the use of an isotopically heavy labelled GnRH peptide, GnRH (Pro(13)C5,(15)N), as the internal standard provides compensation for these parameters. Within the current limits of detection GnRH was detectable up to 1h post administration in urine and identification of a urinary catabolite extended this detection window to 4h. Based on the results of this preliminary investigation we propose the use of aptamers as a viable alternative to antibodies in the enrichment of peptide targets from equine urine. Copyright © 2016 Elsevier B.V. All rights reserved.

Conducted interference on smart meters

NARCIS (Netherlands)

Keyer, Cornelis H.A.; Leferink, Frank

2017-01-01

The increasing conducted interference caused by modern electronic equipment is causing more problems for electronic, or static, energy meters. These meters are called smart meters when equipped with a communication link, and are replacing the conventional electromechanical meters. It is known that

Optimal Meter Placement for Distribution Network State Estimation: A Circuit Representation Based MILP Approach

DEFF Research Database (Denmark)

Chen, Xiaoshuang; Lin, Jin; Wan, Can

2016-01-01

State estimation (SE) in distribution networks is not as accurate as that in transmission networks. Traditionally, distribution networks (DNs) are lack of direct measurements due to the limitations of investments and the difficulties of maintenance. Therefore, it is critical to improve the accuracy...... of SE in distribution networks by placing additional physical meters. For state-of-the-art SE models, it is difficult to clearly quantify measurements' influences on SE errors, so the problems of optimal meter placement for reducing SE errors are mostly solved by heuristic or suboptimal algorithms....... Under this background, this paper proposes a circuit representation model to represent SE errors. Based on the matrix formulation of the circuit representation model, the problem of optimal meter placement can be transformed to a mixed integer linear programming problem (MILP) via the disjunctive model...

Fundamentals of passive nondestructive assay of fissionable material: laboratory workbook

International Nuclear Information System (INIS)

Reilly, T.D.; Augustson, R.H.; Parker, J.L.; Walton, R.B.; Atwell, T.L.; Umbarger, C.J.; Burns, C.E.

1975-02-01

This workbook is a supplement to LA-5651-M, ''Fundamentals of Passive Nondestructive Assay of Fissionable Material'' which is the text used during the Nondestructive Assay Training Session given by Group A-1 of the Los Alamos Scientific Laboratory. It contains the writeups used during the six laboratory sessions covering basic gamma-ray principles, quantitative gamma-ray measurements, uranium enrichment measurements, equipment holdup measurements, basic neutron principles, and quantitative neutron assay

Net metering study of switching effects on electromechanical meters[Report prepared for the Measurement Canada Electricity Net Metering Project

Energy Technology Data Exchange (ETDEWEB)

Van Overberghe, L. [Measurement Canada, London, ON (Canada)

2006-03-03

The feasibility of introducing net metering in the electricity sector was evaluated with particular reference to a project administered by Measurement Canada and Electro-Federation Canada (MicroPower Connect) in collaboration with Natural Resources Canada. The objective of the Measurement Canada Electricity Net Metering Project is to identify and eliminate the barriers introduced by the Electricity and Gas Inspection Act regarding the introduction of net metering. The purpose was to design a device that would allow rotation reversal in a residential electromechanical single phase meter. The device should approximate any fluctuations found in a typical net metering system. A series of tests were conducted to understand the influences, on errors, of forward-to-reverse and reverse-to-forward transitions, specifically to find evidence of error migration and mechanical stress. The project was designed to find and measure the effects of forward reverse switching on an electromechanical meter resulting from a change in energy flow. Twenty metres were calibrated in the forward direction in series from light load to high load. Power factor was not adjustable. Test points were then applied in both the forward and reverse directions. The exercise yielded individual errors which were aggregated to show average found errors after 3,000 transitions. Small shifts in errors were apparent and there was no evidence to support a disk flutter theory. refs., tabs., figs.

Assessment of the disc pasture meter on natural veld in the False ...

African Journals Online (AJOL)

The use of the standard disc pasture meter is found to be a reliable technique for estimating the yield of the densely tufted grass swards found in the False Thornveld of the Eastern Province. It compares favourably with traditional methods of yield estimation in the veld type and its attractiveness lies in the rapidity with which ...

A volumetric meter chip for point-of-care quantitative detection of bovine catalase for food safety control.

Science.gov (United States)

Cui, Xingye; Hu, Jie; Choi, Jane Ru; Huang, Yalin; Wang, Xuemin; Lu, Tian Jian; Xu, Feng

2016-09-07

A volumetric meter chip was developed for quantitative point-of-care (POC) analysis of bovine catalase, a bioindicator of bovine mastitis, in milk samples. The meter chip displays multiplexed quantitative results by presenting the distance of ink bar advancement that is detectable by the naked eye. The meter chip comprises a poly(methyl methacrylate) (PMMA) layer, a double-sided adhesive (DSA) layer and a glass slide layer fabricated by the laser-etching method, which is typically simple, rapid (∼3 min per chip), and cost effective (∼$0.2 per chip). Specially designed "U shape" reaction cells are covered by an adhesive tape that serves as an on-off switch, enabling the simple operation of the assay. As a proof of concept, we employed the developed meter chip for the quantification of bovine catalase in raw milk samples to detect catalase concentrations as low as 20 μg/mL. The meter chip has great potential to detect various target analytes for a wide range of POC applications. Copyright © 2016 Elsevier B.V. All rights reserved.

Acoustic propagation in viscous fluid with uniform flow and a novel design methodology for ultrasonic flow meter.

Science.gov (United States)

Chen, Yong; Huang, Yiyong; Chen, Xiaoqian

2013-02-01

Ultrasonic flow meter with non-invasive no-moving-parts construction has good prospective application for space on-orbit fluid gauging. In traditional pulse transit time flow meter, inconsistency of ultrasonic transducers leads to measurement error and plane wave theory, bases of transit time flow meter, is valuable only for low-frequency wave propagation in inviscid fluid and will lose feasibility when fluid viscosity is considered. In this paper, based on the hydrodynamics of viscous fluid, wave propagation with uniform flow profile is mathematically formulated and a novel solution for viscous fluid using potential theory is firstly presented. Then a novel design methodology of continuous ultrasonic flow meter is proposed, where high measurement rangeability and accuracy are guaranteed individually by solving the integral ambiguity using multi-tone wide laning strategy and the fractional phase shift using phase lock loop tracking method. A comparison with transit time ultrasonic flow meter shows the advantage of proposed methodology. In the end, parametric analysis of viscosity on wave propagation and ultrasonic flow meter is compressively investigated. Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved.

Lab-on-a-Chip-Based PCR-RFLP Assay for the Detection of Malayan Box Turtle (Cuora amboinensis) in the Food Chain and Traditional Chinese Medicines

Science.gov (United States)

Asing; Ali, Md. Eaqub; Abd Hamid, Sharifah Bee; Hossain, M. A. Motalib; Mustafa, Shuhaimi; Kader, Md. Abdul; Zaidul, I. S. M.

2016-01-01

The Malayan box turtle (Cuora amboinensis) (MBT) is a vulnerable and protected turtle species, but it is a lucrative item in the illegal wildlife trade because of its great appeal as an exotic food item and in traditional medicine. Although several polymerase chain reaction (PCR) assays to identify MBT by various routes have been documented, their applicability for forensic authentication remains inconclusive due to the long length of the amplicon targets, which are easily broken down by natural decomposition, environmental stresses or physiochemical treatments during food processing. To address this research gap, we developed, for the first time, a species-specific PCR-restriction fragment length polymorphism (RFLP) assay with a very short target length (120 bp) to detect MBT in the food chain; this authentication ensured better security and reliability through molecular fingerprints. The PCR-amplified product was digested with Bfa1 endonuclease, and distinctive restriction fingerprints (72, 43 and 5 bp) for MBT were found upon separation in a microfluidic chip-based automated electrophoresis system, which enhances the resolution of short oligos. The chances of any false negative identifications were eliminated through the use of a universal endogenous control for eukaryotes, and the limit of detection was 0.0001 ng DNA or 0.01% of the meat under admixed states. Finally, the optimized PCR-RFLP assay was validated for the screening of raw and processed commercial meatballs, burgers and frankfurters, which are very popular in most countries. The optimized PCR-RFLP assay was further used to screen MBT materials in 153 traditional Chinese medicines of 17 different brands and 62 of them were found MBT positive; wherein the ingredients were not declared in product labels. Overall, the novel assay demonstrated sufficient merit for use in any forensic and/or archaeological authentication of MBT, even under a state of decomposition. PMID:27716792

Lab-on-a-Chip-Based PCR-RFLP Assay for the Detection of Malayan Box Turtle (Cuora amboinensis) in the Food Chain and Traditional Chinese Medicines.

Science.gov (United States)

Asing; Ali, Md Eaqub; Abd Hamid, Sharifah Bee; Hossain, M A Motalib; Mustafa, Shuhaimi; Kader, Md Abdul; Zaidul, I S M

2016-01-01

The Malayan box turtle (Cuora amboinensis) (MBT) is a vulnerable and protected turtle species, but it is a lucrative item in the illegal wildlife trade because of its great appeal as an exotic food item and in traditional medicine. Although several polymerase chain reaction (PCR) assays to identify MBT by various routes have been documented, their applicability for forensic authentication remains inconclusive due to the long length of the amplicon targets, which are easily broken down by natural decomposition, environmental stresses or physiochemical treatments during food processing. To address this research gap, we developed, for the first time, a species-specific PCR-restriction fragment length polymorphism (RFLP) assay with a very short target length (120 bp) to detect MBT in the food chain; this authentication ensured better security and reliability through molecular fingerprints. The PCR-amplified product was digested with Bfa1 endonuclease, and distinctive restriction fingerprints (72, 43 and 5 bp) for MBT were found upon separation in a microfluidic chip-based automated electrophoresis system, which enhances the resolution of short oligos. The chances of any false negative identifications were eliminated through the use of a universal endogenous control for eukaryotes, and the limit of detection was 0.0001 ng DNA or 0.01% of the meat under admixed states. Finally, the optimized PCR-RFLP assay was validated for the screening of raw and processed commercial meatballs, burgers and frankfurters, which are very popular in most countries. The optimized PCR-RFLP assay was further used to screen MBT materials in 153 traditional Chinese medicines of 17 different brands and 62 of them were found MBT positive; wherein the ingredients were not declared in product labels. Overall, the novel assay demonstrated sufficient merit for use in any forensic and/or archaeological authentication of MBT, even under a state of decomposition.

Fundamentals of passive nondestructive assay of fissionable material: laboratory workbook

Energy Technology Data Exchange (ETDEWEB)

Reilly, T.D.; Augustson, R.H.; Parker, J.L. Walton, R.B.; Atwell, T.L.; Umbarger, C.J.; Burns, C.E.

1975-02-01

This workbook is a supplement to LA-5651-M, ''Fundamentals of Passive Nondestructive Assay of Fissionable Material'' which is the text used during the Nondestructive Assay Training Session given by Group A-1 of the Los Alamos Scientific Laboratory. It contains the writeups used during the six laboratory sessions covering basic gamma-ray principles, quantitative gamma-ray measurements, uranium enrichment measurements, equipment holdup measurements, basic neutron principles, and quantitative neutron assay.

Development of a plutonium solution-assay instrument with isotopic capability

International Nuclear Information System (INIS)

Hsue, S.T.; Marks, T.

1992-01-01

A new generation of solution-assay instrument has been developed to satisfy all the assay requirements of an aqueous plutonium-recovery operation. The assay is based on a transmission-corrected passive assay technique. We have demonstrated that the system can cover a concentration range of 0.5--300 g/ell with simultaneous isotopic determination. The system can be used to assay input and eluate streams of the recovery operation. The system can be modified to measure low-concentration effluent solutions from the recovery operation covering 0.01--40 g/ell. The same system has also been modified to assay plutonium solutions enriched in 242 Pu. 6 refs

Rover waste assay system

International Nuclear Information System (INIS)

Akers, D.W.; Stoots, C.M.; Kraft, N.C.; Marts, D.J.

1997-01-01

The Rover Waste Assay System (RWAS) is a nondestructive assay system designed for the rapid assay of highly-enriched 235 U contaminated piping, tank sections, and debris from the Rover nuclear rocket fuel processing facility at the Idaho Chemical Processing Plant. A scanning system translates a NaI(Tl) detector/collimator system over the structural components where both relative and calibrated measurements for 137 Cs are made. Uranium-235 concentrations are in operation and is sufficiently automated that most functions are performed by the computer system. These functions include system calibration, problem identification, collimator control, data analysis, and reporting. Calibration of the system was done through a combination of measurements on calibration standards and benchmarked modeling. A description of the system is presented along with the methods and uncertainties associated with the calibration and analysis of the system for components from the Rover facility. 4 refs., 2 figs., 4 tabs

Effects of varying hydraulics on the calibration of eight path chordal ultrasonic meters

International Nuclear Information System (INIS)

Hauser, E.; Estrada, H.; Regan, J.

2003-01-01

Eight path transit time ultrasonic meters are being used in the US, Europe and Japan to support measurement uncertainty power uprates of nuclear power plants. Power uprates rely on the demonstration of improved power accuracy to justify a reduction in the traditional 2% margin between operating power and the power at which loss of coolant accidents and other transients have been analyzed. The flow, density and enthalpy of the feedwater are key elements in the power calculation, and the eight path ultrasonic meters measure the flow and temperature from which these elements are derived. A key element in the uncertainty analysis for these meters is an allowance for the uncertainties that the feedwater flow profiles introduce in the meters' flow calibrations. To minimize and bound this uncertainty calibration tests are performed on each eight path element to be used in an uprate application. This paper describes extensive testing of a prototype eight path meter, results of which have be used to define the sensitivity of 8 path meters to broad variations in flow profiles, both axial and transverse and to establish a methodology whereby the impact of these changes on the uncertainty of the meters can be minimized. This testing confirms the general insensitivity of 8 path chordal systems to axial and transverse fluid velocity profiles. An 8 path chordal system provides a quantitative measurement of the flatness of the axial profile, which allows a quantitative assessment of the differences in hydraulic profile seen by a meter in a plant versus the hydraulic profile seen by that same meter in the calibration lab. Since the sensitivity of the meter's calibration can be established as a function of profile flatness in the lab through parametric testing, the profile flatness in the plant can be used to confirm or to adapt as necessary the calibration coefficient measured in the lab for use in the plant. (author)

Enrichment and purification process of astragalosides and their anti ...

African Journals Online (AJOL)

2014-03-01

Mar 1, 2014 ... water until there was no smell of ethanol and set aside. Enrichment and .... Detection of the effect of astragelosides on cell proliferation by. MTT assay6-7 ... relatively large leakage starting from 10 BV; mass con- centration of ...

Fundamental principles of rotary displacement meters

Energy Technology Data Exchange (ETDEWEB)

Rosen, J. [Schlumberger Industries, Owenton, KY (United States)

1995-12-01

The gas meter exists to continually and accurately measure the volume of gas supplied over the complete flow range of the load. In effect the gas meter serves as the {open_quotes}cash register{close_quotes} of the gas industry; its accurate and dependable performance ensures fair dealings for both the supplier and the user. An investment both in and of itself, the gas meter should be chosen as a function of its usefullness both over the short term and the long term. Thus in addition to initial cost, one must take into account various associated factors, costs and benefits, including the following: Design Characteristics Application, suitability, Meter features and options, Operation constraints, Installation, Service and maintenance, Repair and replacement, Life expectancy, Compatibility with complimentary products, Correcting devices, Remote reading capabilities, Data generation and gathering, Upgradeabilty. This paper will look at one positive displacement meter, the Rotary meter, and address the fundamentals principals of the technology as well as looking at some of the benefits derived from its application. Rotary positive displacement meters were introduced at the end of last century. Used primarily for metering transmission sized loads, the meters` measuring capabilities have extended to cover nearly all areas of distribution with exception of domestic applications. Rotary meters are available in rated capacities from 800 cfh to 102,000 cfh and operating pressures from 175 PSIG to 1440 PSIG. The use of rotary meters on load ranges in the 800 to 10,000 cfh category has increased and is replacing the use of diaphragm meters because of the smaller relative size of rotaries, and improvements in rangeabilities in the last few years. Turbine meters are usually the meter of choice on loads over 16,000 cfh unless a meter with high rangeability is required because of varying load characteristics, in which case a large foot mounted rotary might still be selected.

Digital temperature meter

Energy Technology Data Exchange (ETDEWEB)

Glowacki, S

1982-01-01

Digital temperature meter for precise temperature measurements is presented. Its parts such as thermostat, voltage-frequency converter and digital frequency meter are described. Its technical parameters such as temperature range 50degC-700degC, measurement precision 1degC, measurement error +-1degC are given. (A.S.).

Ultrasonic flow meter

NARCIS (Netherlands)

Lötters, Joost Conrad; Snijders, G.J.; Volker, A.W.F.

2014-01-01

The invention relates to an ultrasonic flow meter comprising a flow tube for the fluid whose flow rate is to be determined. The flow meter comprises a transmitting element for emitting ultrasonic waves, which is provided on the outer jacket of the flow tube. A receiving element, which is provided on

Federal Building Metering Guidance (per 42 U.S.C. 8253(e), Metering of Energy Use)

Energy Technology Data Exchange (ETDEWEB)

None

2014-11-01

Guidance defines which federal buildings are appropriate to meter, provides metering prioritization recommendations for agencies with limited resources, and discusses the requirement for agencies to submit metering implementation plans to the U.S. Department of Energy.

Rover waste assay system

Energy Technology Data Exchange (ETDEWEB)

Akers, D.W.; Stoots, C.M.; Kraft, N.C.; Marts, D.J. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

1997-11-01

The Rover Waste Assay System (RWAS) is a nondestructive assay system designed for the rapid assay of highly-enriched {sup 235}U contaminated piping, tank sections, and debris from the Rover nuclear rocket fuel processing facility at the Idaho Chemical Processing Plant. A scanning system translates a NaI(Tl) detector/collimator system over the structural components where both relative and calibrated measurements for {sup 137}Cs are made. Uranium-235 concentrations are in operation and is sufficiently automated that most functions are performed by the computer system. These functions include system calibration, problem identification, collimator control, data analysis, and reporting. Calibration of the system was done through a combination of measurements on calibration standards and benchmarked modeling. A description of the system is presented along with the methods and uncertainties associated with the calibration and analysis of the system for components from the Rover facility. 4 refs., 2 figs., 4 tabs.

Improved verification methods for safeguards verifications at enrichment plants

International Nuclear Information System (INIS)

Lebrun, A.; Kane, S. C.; Bourva, L.; Poirier, S.; Loghin, N. E.; Langlands, D.

2009-01-01

The International Atomic Energy Agency (IAEA) has initiated a coordinated research and development programme to improve its verification methods and equipment applicable to enrichment plants. The programme entails several individual projects to meet the objectives of the IAEA Safeguards Model Approach for Gas Centrifuge Enrichment Plants updated in 2006. Upgrades of verification methods to confirm the absence of HEU (highly enriched uranium) production have been initiated and, in particular, the Cascade Header Enrichment Monitor (CHEM) has been redesigned to reduce its weight and incorporate an electrically cooled germanium detector. Such detectors are also introduced to improve the attended verification of UF 6 cylinders for the verification of the material balance. Data sharing of authenticated operator weighing systems such as accountancy scales and process load cells is also investigated as a cost efficient and an effective safeguards measure combined with unannounced inspections, surveillance and non-destructive assay (NDA) measurement. (authors)

Improved verification methods for safeguards verifications at enrichment plants

Energy Technology Data Exchange (ETDEWEB)

Lebrun, A.; Kane, S. C.; Bourva, L.; Poirier, S.; Loghin, N. E.; Langlands, D. [Department of Safeguards, International Atomic Energy Agency, Wagramer Strasse 5, A1400 Vienna (Austria)

2009-07-01

The International Atomic Energy Agency (IAEA) has initiated a coordinated research and development programme to improve its verification methods and equipment applicable to enrichment plants. The programme entails several individual projects to meet the objectives of the IAEA Safeguards Model Approach for Gas Centrifuge Enrichment Plants updated in 2006. Upgrades of verification methods to confirm the absence of HEU (highly enriched uranium) production have been initiated and, in particular, the Cascade Header Enrichment Monitor (CHEM) has been redesigned to reduce its weight and incorporate an electrically cooled germanium detector. Such detectors are also introduced to improve the attended verification of UF{sub 6} cylinders for the verification of the material balance. Data sharing of authenticated operator weighing systems such as accountancy scales and process load cells is also investigated as a cost efficient and an effective safeguards measure combined with unannounced inspections, surveillance and non-destructive assay (NDA) measurement. (authors)

Smart meter status report from Toronto

International Nuclear Information System (INIS)

O'Brien, D.

2006-01-01

An update of Toronto Hydro's smart metering program was presented. Electricity demand is expected to keep increasing, and there is presently insufficient generation to match supply needs in Ontario. The smart metering program was introduced to aid in the Ontario government's energy conservation strategy, as well as to address peak supply problems that have led to power outages. It is expected that the smart metering program will reduce provincial peak supply by 5 per cent, as the meters support both time-of-use rates and critical peak pricing. Over 800,000 smart meters will be supplied to customers by 2007, and all 4.3 million homes in Toronto will have a smart meter by 2010. In order to meet targets for 2010, the utility will continue to install more 15,000 meters each month for the next 4 years. While the Ontario government has planned and coordinated the rollout and developed smart metering specifications and standards, Toronto Hydro is responsible for the purchase, installation, operation and maintenance of the meters. Advance testing of each meter is needed to ensure billing accuracy, and customer education on meter use is also. The complexity of the metering program has led the utility to establish a rigid project management process. Customer education pilot program are currently being conducted. Experience gained during the earlier phases of the program have enabled the utility to select appropriate metering systems based on density, topography and physical conditions. Project expenditures have been within budget due to improved project estimating and planning. The metering program has been conducted in tandem with the utility's peakSAVER program, a residential and small commercial load control program that has been successful in reducing summer peak demand by cycling air conditioners without causing discomfort. It was concluded that the utility will continue with its mass deployment of smart meters, and is currently preparing its call center to handled

Streamlining Smart Meter Data Analytics

OpenAIRE

Liu, Xiufeng; Nielsen, Per Sieverts

2015-01-01

Today smart meters are increasingly used in worldwide. Smart meters are the advanced meters capable of measuring customer energy consumption at a fine-grained time interval, e.g., every 15 minutes. The data are very sizable, and might be from different sources, along with the other social-economic metrics such as the geographic information of meters, the information about users and their property, geographic location and others, which make the data management very complex. On the other hand, ...

Calibration of reference KAP-meters at SSDL and cross calibration of clinical KAP-meters

International Nuclear Information System (INIS)

Hetland, Per O.; Friberg, Eva G.; Oevreboe, Kirsti M.; Bjerke, Hans H.

2009-01-01

In the summer of 2007 the secondary standard dosimetry laboratory (SSDL) in Norway established a calibration service for reference air-kerma product meter (KAP-meter). The air-kerma area product, PKA, is a dosimetric quantity that can be directly related to the patient dose and used for risk assessment associated with different x-ray examinations. The calibration of reference KAP-meters at the SSDL gives important information on parameters influencing the calibration factor for different types of KAP-meters. The use of reference KAP-meters calibrated at the SSDL is an easy and reliable way to calibrate or verify the PKA indicated by the x-ray equipment out in the clinics. Material and methods. Twelve KAP-meters were calibrated at the SSDL by use of the substitution method at five diagnostic radiation qualities (RQRs). Results. The calibration factors varied from 0.94 to 1.18. The energy response of the individual KAP-meters varied by a total of 20% between the different RQRs and the typical chamber transmission factors ranged from 0.78 to 0.91. Discussion. It is important to use a calibrated reference KAP-meter and a harmonised calibration method in the PKA calibration in hospitals. The obtained uncertainty in the PKA readings is comparable with other calibration methods if the information in the calibration certificate is correct used, corrections are made and proper positioning of the KAP-chamber is performed. This will ensure a reliable estimate of the patient dose and a proper optimisation of conventional x-ray examinations and interventional procedures

Solid state semiconductor detectorized survey meter

International Nuclear Information System (INIS)

Okamoto, Eisuke; Nagase, Yoshiyuki; Furuhashi, Masato

1987-01-01

Survey meters are used for measurement of gamma ray dose rate of the space and the surface contamination dencity that the atomic energy plant and the radiation facility etc. We have recently developed semiconductor type survey meter (Commercial name: Compact Survey Meter). This survey meter is a small-sized dose rate meter with excellent function. The special features are using semiconductor type detector which we have developed by our own technique, stablar wide range than the old type, long life, and easy to carry. Now we introduce the efficiency and the function of the survey meter. (author)

Simple meters get smart? Cost benefit analysis of smart metering infrastructure

International Nuclear Information System (INIS)

Van Gerwen, R.J.F.; Jaarsma, S.A.; Koenis, F.T.C.

2005-08-01

The Dutch Ministry of Economic Affairs requested a cost-benefit analysis of the large scale introduction of a smart meter infrastructure for gas and electricity consumption by small consumers. The questions asked in the study need to be answered in order to enable a well-founded evaluation of the implementation of smart meters. [mk] [nl

Metering apparatus and tariffs for electricity supply

International Nuclear Information System (INIS)

1990-01-01

Conference papers presented cover system economies and tariff structure with papers on pricing of electricity and new metering technologies. Other topics reviewed include metering apparatus design, electronic metering apparatus and solid phase metering technology. Meter data retrieval, bulk supply metering, test equipment and maintenance, and legal requirements and standards are discussed. (author)

Cross-cultural differences in meter perception.

Science.gov (United States)

Kalender, Beste; Trehub, Sandra E; Schellenberg, E Glenn

2013-03-01

We examined the influence of incidental exposure to varied metrical patterns from different musical cultures on the perception of complex metrical structures from an unfamiliar musical culture. Adults who were familiar with Western music only (i.e., simple meters) and those who also had limited familiarity with non-Western music were tested on their perception of metrical organization in unfamiliar (Turkish) music with simple and complex meters. Adults who were familiar with Western music detected meter-violating changes in Turkish music with simple meter but not in Turkish music with complex meter. Adults with some exposure to non-Western music that was unmetered or metrically complex detected meter-violating changes in Turkish music with both simple and complex meters, but they performed better on patterns with a simple meter. The implication is that familiarity with varied metrical structures, including those with a non-isochronous tactus, enhances sensitivity to the metrical organization of unfamiliar music.

Multitasking metering enhances generation, transmission operations

Energy Technology Data Exchange (ETDEWEB)

Sullivan, E.

2008-11-15

The Dairyland Power Cooperative (DPC) which operates from La Crosse, Wisconsin has the capacity to generate and transmit 1000 MW of power to 25 member cooperatives and 20 municipalities who serve over 500,000 customers. When DPC was experiencing diminished service within its analog cellular-based data communications system, it was presented with an opportunity to install a new automated telecommunications system that would provide secure collection of meter readings from all of its substations. DPC decided to evaluate an advanced multifunctional digital meter from Schweitzer Engineering Laboratories (SEL). The SEL-734 Revenue Metering System offers complete instantaneous metering functions, including voltages, currents, power, energy and power factor. Other capabilities include predictive demand, time-of-use metering, automatic voltage monitoring, harmonics metering and synchrophasor measurement. From a metering perspective, DPC wanted to perform daily load profiles and interval-by-interval metering of their delivery points for billing purposes. They also wanted to provide real-time monitoring of electricity being delivered for both generation and transmission purposes and to make that information available to a distribution SCADA system for their members. The SEL-734 Revenue Meter was well suited to those needs. The SEL-734 provides very high-accuracy energy metering, load profile data collection, instantaneous power measurements, power quality monitoring, and communicates simultaneously over a modem, serial ports, and wide area networks (WAN). The meter is backed with a ten-year warranty as well as field support engineers. 5 figs.

Smart meter incorporating UWB technology

NARCIS (Netherlands)

Khan, T.A.; Khan, A.B.; Babar, M.; Taj, T.A.

2014-01-01

Smart Meter is a key element in the evolving concept of Smart Grid, which plays an important role in interaction between the consumer and the supplier. In general, the smart meter is an intelligent digital energy meter that measures the consumption of electrical energy and provides other additional

Good standards for smart meters

NARCIS (Netherlands)

Hoenkamp, R.A.; Huitema, G.B.

2012-01-01

This paper examines what lessons can be learned from the rollout of smart meters in the Netherlands to improve the European smart meter standardization. This study is based on the case of the Dutch meter rollout which preparations started in 2005 but finally was delayed until 2011 by governmental

Targeted resequencing and variant validation using pxlence PCR assays

Directory of Open Access Journals (Sweden)

Frauke Coppieters

2016-01-01

Full Text Available The advent of next-generation sequencing technologies had a profound impact on molecular diagnostics. PCR is a popular method for target enrichment of disease gene panels. Using our proprietary primer-design pipeline, primerXL, we have created almost one million assays covering over 98% of the human exome. Here we describe the assay specification and both in silico and wet-lab validation of a selected set of 2294 assays using both next-generation sequencing and Sanger sequencing. Using a universal PCR protocol without optimization, these assays result in high coverage uniformity and limited non-specific coverage. In addition, data indicates a positive correlation between the predictive in silico specificity score and the amount of assay non-specific coverage.

RFID-BASED Prepaid Power Meter

OpenAIRE

Teymourzadeh, Rozita

2013-01-01

An Electric power meter is an important component in electric energy service. In the past, many consumers have complained about reading inaccurate of the electric meter. This research presents the development of an electrical power meter equipped with RFID reader. The RFID reader reads a valid RFID card and activates the power meter so that it can supply electricity. When the credit is about low or before the electricity is auto cut off, an SMS message will be sent to the user’s handphone to ...

Cancer-meter: measure and cure.

Science.gov (United States)

Kashyap, Sunil Kumar; Sharma, Birendra Kumar; Banerjee, Amitabh

2017-05-01

This paper presents a theory and system on "Cancer-Meter'. This idea came through the statement that "cancer is curable if it is measurable". The Cancer-Meter proves that it is possible. This paper proposes the cancer-meter in two ways, theoretical and electronically, as per the measurement and treatment. By the mathematics, first part is defined but the second part is based on computer programming, electrical and electronics. Thus, the cancer-meter is a programmed-electrical-electronic device which measures and cures the cancer both.

A volumetric meter chip for point-of-care quantitative detection of bovine catalase for food safety control

International Nuclear Information System (INIS)

Cui, Xingye; Hu, Jie; Choi, Jane Ru; Huang, Yalin; Wang, Xuemin; Lu, Tian Jian; Xu, Feng

2016-01-01

A volumetric meter chip was developed for quantitative point-of-care (POC) analysis of bovine catalase, a bioindicator of bovine mastitis, in milk samples. The meter chip displays multiplexed quantitative results by presenting the distance of ink bar advancement that is detectable by the naked eye. The meter chip comprises a poly(methyl methacrylate) (PMMA) layer, a double-sided adhesive (DSA) layer and a glass slide layer fabricated by the laser-etching method, which is typically simple, rapid (∼3 min per chip), and cost effective (∼$0.2 per chip). Specially designed “U shape” reaction cells are covered by an adhesive tape that serves as an on-off switch, enabling the simple operation of the assay. As a proof of concept, we employed the developed meter chip for the quantification of bovine catalase in raw milk samples to detect catalase concentrations as low as 20 μg/mL. The meter chip has great potential to detect various target analytes for a wide range of POC applications. - Highlights: • The meter chip is a standalone point-of-care diagnostic tool with visible readouts of quantification results. • A fast and low cost fabrication protocol (~3 min and ~$0.2 per chip) of meter chip was proposed. • The chip may hold the potential for rapid scaning of bovine mastitis in cattle farms for food safety control.

A volumetric meter chip for point-of-care quantitative detection of bovine catalase for food safety control

Energy Technology Data Exchange (ETDEWEB)

Cui, Xingye; Hu, Jie; Choi, Jane Ru; Huang, Yalin; Wang, Xuemin [The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi' an Jiaotong University, Xi' an, 710049 (China); Bioinspired Engineering and Biomechanics Center (BEBC), Xi' an Jiaotong University, Xi' an, 710049 (China); Lu, Tian Jian, E-mail: tjlu@mail.xjtu.edu.cn [Bioinspired Engineering and Biomechanics Center (BEBC), Xi' an Jiaotong University, Xi' an, 710049 (China); Xu, Feng, E-mail: fengxu@mail.xjtu.edu.cn [The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi' an Jiaotong University, Xi' an, 710049 (China); Bioinspired Engineering and Biomechanics Center (BEBC), Xi' an Jiaotong University, Xi' an, 710049 (China)

2016-09-07

A volumetric meter chip was developed for quantitative point-of-care (POC) analysis of bovine catalase, a bioindicator of bovine mastitis, in milk samples. The meter chip displays multiplexed quantitative results by presenting the distance of ink bar advancement that is detectable by the naked eye. The meter chip comprises a poly(methyl methacrylate) (PMMA) layer, a double-sided adhesive (DSA) layer and a glass slide layer fabricated by the laser-etching method, which is typically simple, rapid (∼3 min per chip), and cost effective (∼$0.2 per chip). Specially designed “U shape” reaction cells are covered by an adhesive tape that serves as an on-off switch, enabling the simple operation of the assay. As a proof of concept, we employed the developed meter chip for the quantification of bovine catalase in raw milk samples to detect catalase concentrations as low as 20 μg/mL. The meter chip has great potential to detect various target analytes for a wide range of POC applications. - Highlights: • The meter chip is a standalone point-of-care diagnostic tool with visible readouts of quantification results. • A fast and low cost fabrication protocol (~3 min and ~$0.2 per chip) of meter chip was proposed. • The chip may hold the potential for rapid scaning of bovine mastitis in cattle farms for food safety control.

Privacy friendly aggregation of smart meter readings, even when meters crash

NARCIS (Netherlands)

Hoepman, J.H.

2017-01-01

A well studied privacy problem in the area of smart grids is the question of how to aggregate the sum of a set of smart meter readings in a privacy friendly manner, i.e., in such a way that individual meter readings are not revealed to the adversary. Much less well studied is how to deal with

Enriching traditional biology lectures digital concept maps and their influence on cognition and motivation

Directory of Open Access Journals (Sweden)

Steffen Schaal

2010-04-01

Full Text Available Higher education deals with complex knowledge and university teaching should focus on conceptual understanding. Adequate knowledge structures are essential and active knowledge construction should be supported for meaningful learning. But traditional lectures mostly are structured by slides which may misleadingly cause linear representations of knowledge. In this study, a framework for digital concept maps was developed to complement lectures in human biology. The course was aimed at student science teachers at the undergraduate level. The work is based on theoretical research on computer-supported learning, on knowledge structures perspectives within learning environments as well as on self-determination theory. Each session was supplemented by a digital, multimedia-enriched concept map. After each single lecture, students had free access to the concept maps to reinforce the latest topics. The objective of the study was to examine if the use of complementary concept maps (i influences achievement and (ii if motivational variables influence the use of the concept maps. In both cases, influences of computer-user self-efficacy were expected (iii. The students’ (N = 171 concept map use was logged, achievement was tested and motivational variables were surveyed (e.g. interest/ enjoyment, perceived competence, effort/ importance, value/usefulness. The logfile-data allowed distinguishing learners according to their concept map use. Results reveal the benefit of additional concept maps for achievement, positive motivational aspects and computer-user self-efficacy as mediating factors showed some influence. The emphasize of further research should be on students’ active engagement in structuring their individual learning by constructing concept maps themselves, especially in science education courses.

Digital reactivity meter

International Nuclear Information System (INIS)

Jiang Zongbing

1996-02-01

The importance and the usual methods of reactivity measurement in a nuclear reactor are presented. Emphasis is put upon the calculation principle, software and hardware components, main specifications, application, as well as the features of the digital reactivity meter. The test results of operation in various reactors shown that the meter possess the following features: high accuracy, short response time, low output noise, high resolution, wide measuring range, simple and flexible to operate, high stability and reliability. In addition, the reactivity meter can save the measuring data automatically and have a perfect capability of self-verifying. It not only meet the requirement of the reactivity measurement in nuclear power plant, but also can be applied to various types of reactors. (1 tab.)

Advances in uranium enrichment processes

International Nuclear Information System (INIS)

Rae, H.K.; Melvin, J.G.; Slater, J.B.

1986-05-01

Advances in gas centrifuges and development of the atomic vapour laser isotope separation process promise substantial reductions in the cost of enriched uranium. The resulting reduction in LWR fuel costs could seriously erode the economic advantage of CANDU, and in combination with LWR design improvements, shortened construction times and increased operational reliability could allow the LWR to overtake CANDU. CANDU's traditional advantages of neutron economy and high reliability may no longer be sufficient - this is the challenge. The responses include: combining neutron economy and dollar economy by optimizing CANDU for slightly enriched uranium fuel; developing cost-reducing improvements in design, manufacture and construction; and reducing the cost of heavy water. Technology is a renewable resource which must be continually applied to a product for it to remain competitive in the decades to come. Such innovation is a prerequisite to Canada increasing her share of the international market for nuclear power stations. The higher burn-up achievable with enriched fuel in CANDU can reduce the fuel cycle costs by 20 to 40 percent for a likely range of costs for yellowcake and separative work. Alternatively, some of the benefits of a higher fissile content can take the form of a cheaper reactor core containing fewer fuel channels and less heavy water, and needing only a single fuelling machine. An opportunity that is linked to this need to introduce an enriched uranium fuel cycle into CANDU is to build an enrichment business in Canada. This could offer greater value added to our uranium exports, security of supply for enriched CANDUs, technological growth in Canada and new employment opportunities. AECL has a study in progress to define this opportunity

Smart metering design and applications

CERN Document Server

Weranga, K S K; Chandima, D P

2013-01-01

Taking into account the present day trends and the requirements, this Brief focuses on smart metering of electricity for next generation energy efficiency and conservation. The contents include discussions on the smart metering concepts and existing technologies and systems as well as design and implementation of smart metering schemes together with detailed examples.

Evaluation of an Electrochemical Point-of-Care Meter for Measuring Glucose Concentration in Blood from Periparturient Dairy Cattle.

Science.gov (United States)

Megahed, A A; Hiew, M W H; Townsend, J R; Messick, J B; Constable, P D

2015-01-01

The Precision Xtra(®) meter is a promising low cost electrochemical point-of-care unit for measuring blood glucose concentration ([gluc]) in cattle blood. The meter uses an algorithm that assumes the intra-erythrocyte [gluc] equals the plasma [gluc] on a molal basis, and that the hematocrit is similar in humans and cattle. The primary objective was to determine the accuracy of the meter for measuring plasma [gluc] in dairy cattle. Secondary objectives were to characterize the influence of hematocrit and sample temperature on the measured value for [gluc]. A total of 106 periparturient Holstein-Friesian cattle. Blood and plasma samples (1,109) were obtained and Deming regression and Bland-Altman plots were used to determine the accuracy of the meter against the reference method (plasma hexokinase assay). Multivariable regression and linear regression were used to determine the effect of hematocrit and sample temperature on the plasma [gluc] measured by the meter. Intra-erythrocyte [gluc] was 18% of plasma [gluc] on a molar basis. Sample temperature had a significant linear effect on plasma [gluc] as measured by the meter for 3/5 plasma samples when measured [gluc] > 160 mg/dL. The meter utilizes an algorithm that is optimized for human blood and is inaccurate when applied to bovine blood. Until a cattle-specific algorithm is developed, we recommend using plasma as the analyte instead of blood and calculating plasma [gluc] using the equation: [gluc] = 0.66 × [gluc]p-meter + 15, where [gluc]p-meter is the value reported by the meter. If blood is measured, then we recommend using the equation: [gluc] = 0.90 × [gluc]b-meter + 15. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

Efficient Management of Certificate Revocation Lists in Smart Grid Advanced Metering Infrastructure

Energy Technology Data Exchange (ETDEWEB)

Cebe, Mumin [Florida Intl Univ., Miami, FL (United States); Akkaya, Kemal [Florida Intl Univ., Miami, FL (United States)

2017-07-19

Advanced Metering Infrastructure (AMI) forms a communication network for the collection of power data from smart meters in Smart Grid. As the communication within an AMI needs to be secure, key management becomes an issue due to overhead and limited resources. While using public-keys eliminate some of the overhead of key management, there is still challenges regarding certificates that store and certify the publickeys. In particular, distribution and storage of certificate revocation list (CRL) is major a challenge due to cost of distribution and storage in AMI networks which typically consist of wireless multi-hop networks. Motivated by the need of keeping the CRL distribution and storage cost effective and scalable, in this paper, we present a distributed CRL management model utilizing the idea of distributed hash trees (DHTs) from peer-to-peer (P2P) networks. The basic idea is to share the burden of storage of CRLs among all the smart meters by exploiting the meshing capability of the smart meters among each other. Thus, using DHTs not only reduces the space requirements for CRLs but also makes the CRL updates more convenient. We implemented this structure on ns-3 using IEEE 802.11s mesh standard as a model for AMI and demonstrated its superior performance with respect to traditional methods of CRL management through extensive simulations.

Hydrogen meter prooftesting

International Nuclear Information System (INIS)

McCown, J.J.; Mettler, G.W.

1976-04-01

Two diffusion type hydrogen meters have been tested on the Prototype Applications Loop (PAL). The ANL designed unit was used to monitor hydrogen in sodium during FFTF startup and over a wide range of hydrogen concentrations resulting from chemical additions to the sodium and cover gas. A commercially available meter was added and its performance compared with the ANL unit. Details of the test work are described

Streamlining Smart Meter Data Analytics

DEFF Research Database (Denmark)

Liu, Xiufeng; Nielsen, Per Sieverts

2015-01-01

of the so-called big data possible. This can improve energy management, e.g., help utilities improve the management of energy and services, and help customers save money. As this regard, the paper focuses on building an innovative software solution to streamline smart meter data analytic, aiming at dealing......Today smart meters are increasingly used in worldwide. Smart meters are the advanced meters capable of measuring customer energy consumption at a fine-grained time interval, e.g., every 15 minutes. The data are very sizable, and might be from different sources, along with the other social......-economic metrics such as the geographic information of meters, the information about users and their property, geographic location and others, which make the data management very complex. On the other hand, data-mining and the emerging cloud computing technologies make the collection, management, and analysis...

Evaluation of different disinfectants on the performance of an on-meter dosed amperometric glucose-oxidase-based glucose meter.

Science.gov (United States)

Sarmaga, Don; Dubois, Jeffrey A; Lyon, Martha E

2011-11-01

Off-meter dosed photometric glucose-oxidase-based glucose meters have been reported to be susceptible to interference by hydrogen-peroxide-based disinfecting agents. The objective of this study was to determine if a single application of hydrogen-peroxide-containing Accel® wipe to disinfect an on-meter dosed amperometric glucose-oxidase-based glucose meter will influence its performance. The performance of five on-meter dosed amperometric glucose-oxidase-based glucose meters was determined before and after disinfecting the devices with a single application of either CaviWipes® (14.3% isopropanol and 0.23% diisobutyl-phenoxy-ethoxyethyl dimethyl benzyl ammonium chloride) or Accel (0.5% hydrogen peroxide) wipes. Replicate glucose measurements were conducted before disinfecting the devices, immediately after disinfecting, and then 1 and 2 min postdisinfecting, with measurements in triplicate. Analysis was sequentially completed for five different meters. Results were analyzed by a two-way analysis of variance (Analyze-it software). No clinical ( .05) in glucose concentration were detected when the on-meter dosed amperometric glucose-oxidase-based glucose meters were disinfected with either CaviWipes or Accel wipes and measured immediately or 1 or 2 min postdisinfecting. No clinically significant difference in glucose concentration was detected between meters (glucose oxidase amperometric-based glucose meters are not analytically susceptible to interference by a single application of hydrogen-peroxide-containing Accel disinfectant wipes. © 2011 Diabetes Technology Society.

Endogenous Locus Reporter Assays.

Science.gov (United States)

Liu, Yaping; Hermes, Jeffrey; Li, Jing; Tudor, Matthew

2018-01-01

Reporter gene assays are widely used in high-throughput screening (HTS) to identify compounds that modulate gene expression. Traditionally a reporter gene assay is built by cloning an endogenous promoter sequence or synthetic response elements in the regulatory region of a reporter gene to monitor transcriptional activity of a specific biological process (exogenous reporter assay). In contrast, an endogenous locus reporter has a reporter gene inserted in the endogenous gene locus that allows the reporter gene to be expressed under the control of the same regulatory elements as the endogenous gene, thus more accurately reflecting the changes seen in the regulation of the actual gene. In this chapter, we introduce some of the considerations behind building a reporter gene assay for high-throughput compound screening and describe the methods we have utilized to establish 1536-well format endogenous locus reporter and exogenous reporter assays for the screening of compounds that modulate Myc pathway activity.

Net metering: zero electricity bill

International Nuclear Information System (INIS)

Mangi, A.; Khan, Z.

2011-01-01

Worldwide move towards renewable energy sources, environmental concerns and decentralization of the power sector have made net metering an attractive option for power generation at small scale. This paper discusses the net metering, economical issues of renewable sources in Pakistan, technical aspects, installation suitability according to varying terrain, existing utility rules and formulation of legislation for net metering making it economically attractive. (author)

Modeling of UF{sub 6} enrichment with gas centrifuges for nuclear safeguards activities

Energy Technology Data Exchange (ETDEWEB)

Mercurio, G.; Peerani, P.; Richir, P.; Janssens, W.; Eklund, G. [European Commission, Joint Research Centre, Institute for Transuranium Elements Via Fermi, 2749-TP181,20127 Ispra (Italy)

2012-09-26

The physical modeling of uranium isotopes ({sup 235}U, {sup 238}U) separation process by centrifugation of is a key aspect for predicting the nuclear fuel enrichment plant performances under surveillance by the Nuclear Safeguards Authorities. In this paper are illustrated some aspects of the modeling of fast centrifuges for UF{sub 6} gas enrichment and of a typical cascade enrichment plant with the Theoretical Centrifuge and Cascade Simulator (TCCS). The background theory for reproducing the flow field characteristics of a centrifuge is derived from the work of Cohen where the separation parameters are calculated using the solution of a differential enrichment equation. In our case we chose to solve the hydrodynamic equations for the motion of a compressible fluid in a centrifugal field using the Berman - Olander vertical velocity radial distribution and the solution was obtained using the Matlab software tool. The importance of a correct estimation of the centrifuge separation parameters at different flow regimes, lies in the possibility to estimate in a reliable way the U enrichment plant performances, once the separation external parameters are set (feed flow rate and feed, product and tails assays). Using the separation parameters of a single centrifuge allow to determine the performances of an entire cascade and, for this purpose; the software Simulink was used. The outputs of the calculation are the concentrations (assays) and the flow rates of the enriched (product) and depleted (tails) gas mixture. These models represent a valid additional tool, in order to verify the compliance of the U enrichment plant operator declarations with the 'on site' inspectors' measurements.

New Prototype Safeguards Technology Offers Improved Confidence and Automation for Uranium Enrichment Facilities

Energy Technology Data Exchange (ETDEWEB)

Brim, Cornelia P.

2013-04-01

An important requirement for the international safeguards community is the ability to determine the enrichment level of uranium in gas centrifuge enrichment plants and nuclear fuel fabrication facilities. This is essential to ensure that countries with nuclear nonproliferation commitments, such as States Party to the Nuclear Nonproliferation Treaty, are adhering to their obligations. However, current technologies to verify the uranium enrichment level in gas centrifuge enrichment plants or nuclear fuel fabrication facilities are technically challenging and resource-intensive. NNSA’s Office of Nonproliferation and International Security (NIS) supports the development, testing, and evaluation of future systems that will strengthen and sustain U.S. safeguards and security capabilities—in this case, by automating the monitoring of uranium enrichment in the entire inventory of a fuel fabrication facility. One such system is HEVA—hybrid enrichment verification array. This prototype was developed to provide an automated, nondestructive assay verification technology for uranium hexafluoride (UF6) cylinders at enrichment plants.

Balanced Flow Meters without Moving Parts

Science.gov (United States)

Kelley, Anthony R.; VanBuskirk, Paul

2008-01-01

Balanced flow meters are recent additions to an established class of simple, rugged flow meters that contain no moving parts in contact with flow and are based on measurement of pressure drops across objects placed in flow paths. These flow meters are highly accurate, minimally intrusive, easily manufacturable, and reliable. A balanced flow meter can be easily mounted in a flow path by bolting it between conventional pipe flanges. A balanced flow meter can be used to measure the flow of any of a variety of liquids or gases, provided that it has been properly calibrated. Relative to the standard orifice-plate flow meter, the balanced flow meter introduces less turbulence and two times less permanent pressure loss and is therefore capable of offering 10 times greater accuracy and repeatability with less dissipation of energy. A secondary benefit of the reduction of turbulence is the reduction of vibration and up to 15 times less acoustic noise generation. Both the balanced flow meter and the standard orifice-plate flow meter are basically disks that contain holes and are instrumented with pressure transducers on their upstream and downstream faces. The most obvious difference between them is that the standard orifice plate contains a single, central hole while the balanced flow meter contains multiple holes. The term 'balanced' signifies that in designing the meter, the sizes and locations of the holes are determined in an optimization procedure that involves balancing of numerous factors, including volumetric flow, mass flow, dynamic pressure, kinetic energy, all in an effort to minimize such undesired effects as turbulence, pressure loss, dissipation of kinetic energy, and non-repeatability and nonlinearity of response over the anticipated range of flow conditions. Due to proper balancing of these factors, recent testing demonstrated that the balanced flow-meter performance was similar to a Venturi tube in both accuracy and pressure recovery, but featured reduced

How to use your peak flow meter

Science.gov (United States)

... meter - how to use; Asthma - peak flow meter; Reactive airway disease - peak flow meter; Bronchial asthma - peak ... 2014:chap 55. National Asthma Education and Prevention Program website. How to use a peak flow meter. ...

Serotype determination of Salmonella by xTAG assay.

Science.gov (United States)

Zheng, Zhibei; Zheng, Wei; Wang, Haoqiu; Pan, Jincao; Pu, Xiaoying

2017-10-01

Currently, no protocols or commercial kits are available to determine the serotypes of Salmonella by using Luminex MAGPIX®. In this study, an xTAG assay for serotype determination of Salmonella suitable for Luminex MAGPIX® is described and 228 Salmonella isolates were serotype determined by this xTAG assay. The xTAG assay consists of two steps: 1) Multiplex PCR to amplify simultaneously O, H and Vi antigen genes of Salmonella, and 2) Magplex-TAG™ microsphere hybridization to identify accurately the specific PCR products of different antigens. Compared with the serotyping results of traditional serum agglutination test, the sensitivity and specificity of the xTAG assay were 95.1% and 100%, respectively. The agreement rate of these two assays was 95.2%. Compared with Luminex xMAP® Salmonella Serotyping Assay (SSA) kit, the advantages of this xTAG assay are: First, the magnetic beads make it applicable to both the Luminex®100/200™ and MAGPIX® systems. Second, only primers rather than both primers and probes are needed in the xTAG assay, and the process of coupling antigen-specific oligonucleotide probes to beads is circumvented, which make the xTAG assay convenient to be utilized by other laboratories. The xTAG assay may serve as a rapid alternative or complementary method for traditional Salmonella serotyping tests, especially for laboratories that utilize the MAGPIX® systems. Copyright © 2017 Elsevier B.V. All rights reserved.

¹³⁶ Xe enrichment through cryogenic distillation

Energy Technology Data Exchange (ETDEWEB)

Back, Henning O.; Bottenus, Daniel R.; Clayton, Christopher K.; Stephenson, David E.; TeGrotenhuis, Ward E.

2017-09-01

The next generation of 136Xe neutrinoless double beta decay experiments will require on the order of 5 tons of enriched 136Xe. By estimating the relative volatilities of the xenon isotopes and using standard chemical engineering techniques we explore the feasibility of using cryogenic distillation to produce 5 tons of 80% enriched 136Xe in 5-6 years. With current state-of-the-art distillation column packing materials we can estimate the total height of a traditional cryogenic distillation column. We also, report on how Micro Channel Distillation may reduce the overall size of a distillation system for 136Xe production.

Sector smart meter audit review report

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-03-31

This paper presented the results of an electricity distributor sector smart meter audit review conducted by the Ontario Energy Board (OEB) for the period of January 1, 2006 to September 30, 2009. The review summarized the results of a questionnaire related to distributors' smart meter regulatory accounting treatment. Seventy-eight distributors responded to the survey. The review included details of: (1) total investments in smart metering initiative for capital expenditures (CAPEX) and operating maintenance and administrative expenses (OM and A), (2) funding dollars received by the distributors, (3) board-approved recoveries for CAPEX and OM and A, (4) recorded stranded meter costs, and (5) number of smart meters installed in the review period. The audit review demonstrated that some distributors incorrectly recorded carrying charges related to smart meter OM and A expenses, and that some smart meter transactions were recorded in accounts other than OEB established accounts in the general ledger. Results of the audit will be used to provide further accounting assistance to electricity distributors. 7 tabs.

Impact of fuel-dependent electricity retail charges on the value of net-metered PV applications in vertically integrated systems

International Nuclear Information System (INIS)

Nikolaidis, Alexandros I.; Milidonis, Andreas; Charalambous, Charalambos A.

2015-01-01

Retail electricity charges inevitably influence the financial rationale of using net-metered photovoltaic (PV) applications since their structure as well as their level may vary significantly over the life-cycle of a customer-sited PV generation system. This subsequently introduces a further uncertainty for a ratepayer considering a net-metered PV investment. To thoroughly comprehend this uncertainty, the paper employs a top-down approach – in vertically integrated environments – to model the volatility of partially hedged electricity charges and its subsequent impact on the value of bill savings from net-metered PV systems. Besides the utility's pricing strategy and rate structures, particular emphasis is given in modeling the fossil fuel mix component that introduces a significant source of uncertainty on electricity charges and thus on the value of bill savings of net-metered, customer-sited, PV applications. - Highlights: • A top-down approach of developing traditional electricity charges is provided. • The combined effect of pricing strategies, rate structures and fuels is examined. • Fossil fuel prices can substantially affect the net metering compensation. • A financial risk assessment for net-metered PV systems is performed

Hardware Design of a Smart Meter

OpenAIRE

Ganiyu A. Ajenikoko; Anthony A. Olaomi

2014-01-01

Smart meters are electronic measurement devices used by utilities to communicate information for billing customers and operating their electric systems. This paper presents the hardware design of a smart meter. Sensing and circuit protection circuits are included in the design of the smart meter in which resistors are naturally a fundamental part of the electronic design. Smart meters provides a route for energy savings, real-time pricing, automated data collection and elimina...

Optical cycle power meter

DEFF Research Database (Denmark)

2014-01-01

A bicycle power meter for measuring power generated when riding a bicycle, the power meter comprising a position-sensitive radiation detector (409) attachable to a component of a crank set (404) of bicycle, and a radiation source (408) attachable to the component of the crank set and configured t...

Simulation of a short-cable Q-meter for measuring the deuteron target polarization

International Nuclear Information System (INIS)

Karnaukhov, I.M.; Lukhanin, A.A.; Telegin, Yu.N.; Trotsenko, V.I.; Chechetenko, V.F.

1984-01-01

Simulation of Q-meter with a phase automatic-frequency control of a reception circuit is carried out in the paper. Effect of circuit parameters and connecting cable on Q-meter sensitivity and magnitude of distortions of recorded signal is studied. It is shown that usage of the cable with a length of lambda/12-lambda/10 instead of traditional semiwave one enables to increase essentially the circuit sensitivity at the same distortion rate. Errors conditioned by distortions of the deuteron magnetic resonance (DMR) signal forms in the reception circuit, which can effect essertially on accuracy of deuteron polarization detection by the method of DMR spectrum decomposition, are discussed. It is shown that in the case of utilization of a short cable the polarization error due to spectrum distortions does not exceed 4...5%

Bio-active nanoemulsions enriched with gold nanoparticle, marigold extracts and lipoic acid: In vitro investigations.

Science.gov (United States)

Guler, Emine; Barlas, F Baris; Yavuz, Murat; Demir, Bilal; Gumus, Z Pinar; Baspinar, Yucel; Coskunol, Hakan; Timur, Suna

2014-09-01

A novel and efficient approach for the preparation of enriched herbal formulations was described and their potential applications including wound healing and antioxidant activity (cell based and cell free) were investigated via in vitro cell culture studies. Nigella sativa oil was enriched with Calendula officinalis extract and lipoic acid capped gold nanoparticles (AuNP-LA) using nanoemulsion systems. The combination of these bio-active compounds was used to design oil in water (O/W) and water in oil (W/O) emulsions. The resulted emulsions were characterized by particle size measurements. The phenolic content of each nanoemulsion was examined by using both colorimetric assay and chromatographic analyses. Two different methods containing cell free chemical assay (1-diphenyl-2-picrylhydrazyl method) and cell based antioxidant activity test were used to evaluate the antioxidant capacities. In order to investigate the bio-activities of the herbal formulations, in vitro cell culture experiments, including cytotoxicity, scratch assay, antioxidant activity and cell proliferation were carried out using Vero cell line as a model cell line. Furthermore, to monitor localization of the nanoemulsions after application of the cell culture, the cell images were monitored via fluorescence microscope after FITC labeling. All data confirmed that the enriched N. sativa formulations exhibited better antioxidant and wound healing activity than N. sativa emulsion without any enrichment. In conclusion, the incorporation of AuNP-LA and C. officinalis extract into the N. sativa emulsions significantly increased the bio-activities. The present work may support further studies about using the other bio-active agents for the enrichment of herbal preparations to strengthen their activities. Copyright © 2014 Elsevier B.V. All rights reserved.

Field experience of a project with the Dutch Consultancy Services Wind Energy Developing Countries (CWD) and traditional wind pumps in Nicaragua

International Nuclear Information System (INIS)

Holtslag, H.A.G.

1991-01-01

The main objective of the title project, which started in October 1986, was to promote the use of wind energy in Nicaragua by means of a study on the wind potential, the production and use of wind pumps, and repairs of traditional wind pumps. Involved in the project were a Dutch project coordinator, a Dutch, a German and a Danish advisor for the technical aspects and a Dutch advisor for irrigation. The Nicaraguan National Institute of Energy coordinated the project until 1988. Then the (state) factory, where the mills were manufactured, took over. The study on the wind potential was only partly completed. The production was done at the state factory in Managua (IMEP), where two models were produced: a traditional mill with a rotor of 3 meter, and a CWD-mill with a rotor of 5 meter. Adaptations, based on field experiences, were made in the CWD-model in the third year of the project. The total production after 4 years was 50 mills of 3 meter and 15 mills of 5 meter. The objective was 200 mills per year after the third year of the project. Of the 3 meter mill, 35 were installed and used mainly for cattle watering (sales price US$ 2,200). Of the 5 meter mill, 7 were installed in demonstration projects for small-scale irrigation (sales price US$ 4,000). The production rate of the 3 meter mill at the end of the project was 10 mills per 8 weeks. Production of the 5 meter mill stopped for several reasons, but may go on when adaptations in the mill prove to be effective. Repairs of the traditional mills could not be realized. The overall conclusion is that the achievements of the project were lower than the original objectives for reasons which are formulated in the conclusions. 3 ills

Net metering in British Columbia : white paper

International Nuclear Information System (INIS)

Berry, T.

2003-01-01

Net metering was described as being the reverse registration of an electricity customer's revenue meter when interconnected with a utility's grid. It is a provincial policy designed to encourage small-distributed renewable power generation such as micro-hydro, solar energy, fuel cells, and larger-scale wind energy. It was noted that interconnection standards for small generation is an important issue that must be addressed. The British Columbia Utilities Commission has asked BC Hydro to prepare a report on the merits of net metering in order to support consultations on a potential net metering tariff application by the utility. This report provides information on net metering with reference to experience in other jurisdictions with net metering, and the possible costs and benefits associated with net metering from both a utility and consumer perspective. Some of the barriers and policy considerations for successful implementation of net metering were also discussed. refs., tabs., figs

Molecular assays for the detection of prostate tumor derived nucleic acids in peripheral blood

Directory of Open Access Journals (Sweden)

Kinnunen Martin

2010-07-01

Full Text Available Abstract Background Prostate cancer is the second leading cause of cancer mortality in American men. Although serum PSA testing is widely used for early detection, more specific prognostic tests are needed to guide treatment decisions. Recently, the enumeration of circulating prostate epithelial cells has been shown to correlate with disease recurrence and metastasis following definitive treatment. The purpose of our study was to investigate an immunomagnetic fractionation procedure to enrich circulating prostate tumor cells (CTCs from peripheral blood specimens, and to apply amplified molecular assays for the detection of prostate-specific markers (PSA, PCA3 and TMPRSS2:ERG gene fusion mRNAs. Results As few as five prostate cancer cells were detected per 5 mL of whole blood in model system experiments using anti-EpCAM magnetic particles alone or in combination with anti-PSMA magnetic particles. In our experiments, anti-EpCAM magnetic particles alone exhibited equivalent or better analytical performance with patient samples compared to a combination of anti-EpCAM + anti-PSMA magnetic particles. Up to 39% of men with advanced prostate cancer tested positive with one or more of the molecular assays tested, whereas control samples from men with benign prostate hyperplasia gave consistently negative results as expected. Interestingly, for the vast majority of men who tested positive for PSA mRNA following CTC enrichment, their matched plasma samples also tested positive, although CTC enrichment gave higher overall mRNA copy numbers. Conclusion CTCs were successfully enriched and detected in men with advanced prostate cancer using an immunomagnetic enrichment procedure coupled with amplified molecular assays for PSA, PCA3, and TMPRSS2:ERG gene fusion mRNAs. Our results indicate that men who test positive following CTC enrichment also exhibit higher detectable levels of non-cellular, circulating prostate-specific mRNAs.

Anticoagulants Influence the Performance of In Vitro Assays Intended for Characterization of Nanotechnology-Based Formulations

Directory of Open Access Journals (Sweden)

Edward Cedrone

2017-12-01

Full Text Available The preclinical safety assessment of novel nanotechnology-based drug products frequently relies on in vitro assays, especially during the early stages of product development, due to the limited quantities of nanomaterials available for such studies. The majority of immunological tests require donor blood. To enable such tests one has to prevent the blood from coagulating, which is usually achieved by the addition of an anticoagulant into blood collection tubes. Heparin, ethylene diamine tetraacetic acid (EDTA, and citrate are the most commonly used anticoagulants. Novel anticoagulants such as hirudin are also available but are not broadly used. Despite the notion that certain anticoagulants may influence assay performance, a systematic comparison between traditional and novel anticoagulants in the in vitro assays intended for immunological characterization of nanotechnology-based formulations is currently not available. We compared hirudin-anticoagulated blood with its traditional counterparts in the standardized immunological assay cascade, and found that the type of anticoagulant did not influence the performance of the hemolysis assay. However, hirudin was more optimal for the complement activation and leukocyte proliferation assays, while traditional anticoagulants citrate and heparin were more appropriate for the coagulation and cytokine secretion assays. The results also suggest that traditional immunological controls such as lipopolysaccharide (LPS are not reliable for understanding the role of anticoagulant in the assay performance. We observed differences in the test results between hirudin and traditional anticoagulant-prepared blood for nanomaterials at the time when no such effects were seen with traditional controls. It is, therefore, important to recognize the advantages and limitations of each anticoagulant and consider individual nanoparticles on a case-by-case basis.

Nondestructive assay methods for irradiated nuclear fuels

International Nuclear Information System (INIS)

Hsue, S.T.; Crane, T.W.; Talbert, W.L. Jr.; Lee, J.C.

1978-01-01

This report is a review of the status of nondestructive assay (NDA) methods used to determine burnup and fissile content of irradiated nuclear fuels. The gamma-spectroscopy method measures gamma activities of certain fission products that are proportional to the burnup. Problems associated with this method are migration of the fission products and gamma-ray attenuation through the relatively dense fuel material. The attenuation correction is complicated by generally unknown activity distributions within the assemblies. The neutron methods, which usually involve active interrogation and prompt or delayed signal counting, are designed to assay the fissile content of the spent-fuel elements. Systems to assay highly enriched spent-fuel assemblies have been tested extensively. Feasibility studies have been reported of systems to assay light-water reactor spent-fuel assemblies. The slowing-down spectrometer and neutron resonance absorption methods can distinguish between the uranium and plutonium fissile contents, but they are limited to the assay of individual rods. We have summarized the status of NDA techniques for spent-fuel assay and present some subjects in need of further investigation. Accuracy of the burnup calculations for power reactors is also reviewed

ATD-2 Surface Scheduling and Metering Concept

Science.gov (United States)

Coppenbarger, Richard A.; Jung, Yoon Chul; Capps, Richard Alan; Engelland, Shawn A.

2017-01-01

This presentation describes the concept of ATD-2 tactical surface scheduling and metering. The concept is composed of several elements, including data exchange and integration; surface modeling; surface scheduling; and surface metering. The presentation explains each of the elements. Surface metering is implemented to balance demand and capacity• When surface metering is on, target times from surface scheduler areconverted to advisories for throttling demand• Through the scheduling process, flights with CTOTs will not get addedmetering delay (avoids potential for ‘double delay’)• Carriers can designate certain flights as exempt from metering holds• Demand throttle in Phase 1 at CLT is through advisories sent to rampcontrollers for pushback instructions to the flight deck– Push now– Hold for an advised period of time (in minutes)• Principles of surface metering can be more generally applied to otherairports in the NAS to throttle demand via spot-release times (TMATs Strong focus on optimal use of airport resources• Flexibility enables stakeholders to vary the amount of delay theywould like transferred to gate• Addresses practical aspects of executing surface metering in aturbulent real world environment• Algorithms designed for both short term demand/capacityimbalances (banks) or sustained metering situations• Leverage automation to enable surface metering capability withoutrequiring additional positions• Represents first step in Tactical/Strategic fusion• Provides longer look-ahead calculations to enable analysis ofstrategic surface metering potential usage

Evaluation of the BD Max Cdiff assay for the detection of toxigenic Clostridium difficile in human stool specimens.

Science.gov (United States)

Putsathit, Papanin; Morgan, Justin; Bradford, Damien; Engelhardt, Nelly; Riley, Thomas V

2015-02-01

The Becton Dickinson (BD) PCR-based GeneOhm Cdiff assay has demonstrated a high sensitivity and specificity for detecting Clostridium difficile. Recently, the BD Max platform, using the same principles as BD GeneOhm, has become available in Australia. This study aimed to investigate the sensitivity and specificity of BD Max Cdiff assay for the detection of toxigenic C. difficile in an Australian setting. Between December 2013 and January 2014, 406 stool specimens from 349 patients were analysed with the BD Max Cdiff assay. Direct and enrichment toxigenic culture were performed on bioMérieux ChromID C. difficile agar as a reference method. isolates from specimens with discrepant results were further analysed with an in-house PCR to detect the presence of toxin genes. The overall prevalence of toxigenic C. difficile was 7.2%. Concordance between the BD Max assay and enrichment culture was 98.5%. The sensitivity, specificity, positive predictive value and negative predictive value for the BD Max Cdiff assay were 95.5%, 99.0%, 87.5% and 99.7%, respectively, when compared to direct culture, and 91.7%, 99.0%, 88.0% and 99.4%, respectively, when compared to enrichment culture. The new BD Max Cdiff assay appeared to be an excellent platform for rapid and accurate detection of toxigenic C. difficile.

Tunable, Quantitative Fenton-RAFT Polymerization via Metered Reagent Addition.

Science.gov (United States)

Nothling, Mitchell D; McKenzie, Thomas G; Reyhani, Amin; Qiao, Greg G

2018-05-10

A continuous supply of radical species is a key requirement for activating chain growth and accessing quantitative monomer conversions in reversible addition-fragmentation chain transfer (RAFT) polymerization. In Fenton-RAFT, activation is provided by hydroxyl radicals, whose indiscriminate reactivity and short-lived nature poses a challenge to accessing extended polymerization times and quantitative monomer conversions. Here, an alternative Fenton-RAFT procedure is presented, whereby radical generation can be finely controlled via metered dosing of a component of the Fenton redox reaction (H 2 O 2 ) using an external pumping system. By limiting the instantaneous flux of radicals and ensuring sustained radical generation over tunable time periods, metered reagent addition reduces unwanted radical "wasting" reactions and provides access to consistent quantitative monomer conversions with high chain-end fidelity. Fine tuning of radical concentration during polymerization is achieved simply via adjustment of reagent dose rate, offering significant potential for automation. This modular strategy holds promise for extending traditional RAFT initiation toward more tightly regulated radical concentration profiles and affords excellent prospects for the automation of Fenton-RAFT polymerization. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Preparation and characterization of a laboratory scale selenomethionine-enriched bread. Selenium bioaccessibility.

Science.gov (United States)

Sánchez-Martínez, María; Pérez-Corona, Teresa; Caímara, Carmen; Madrid, Yolanda

2015-01-14

This study focuses on the preparation at lab scale of selenomethionine-enriched white and wholemeal bread. Selenium was supplemented either by adding selenite directly to the dough or by using lab-made selenium-enriched yeast. The best results were obtained when using fresh selenium-enriched yeast. The optimum incubation time for selenomethionine-enriched yeast preparation, while keeping formation of selenium byproducts to a minimum, was 96 h. Selenium content measured by isotope dilution analysis (IDA)-ICP-MS in Se-white and Se-wholemeal bread was 1.28 ± 0.02 μg g–1 and 1.16 ± 0.02 μg g–1 (expressed as mean ± SE, 3 replicates), respectively. HPLC postcolumn IDA-ICP-MS measurements revealed that selenomethionine was the main Se species found in Se-enriched bread, which accounted for ca. 80% of total selenium. In vitro gastrointestinal digestion assay provided selenium bioaccessibility values of 100 ± 3% and 40 ± 1% for white and wholemeal Se-enriched bread, respectively, being selenomethionine the main bioaccessible Se species in white bread, while in wholemeal bread this compound was undetectable.

Digital reactivity meter

International Nuclear Information System (INIS)

Akkus, B.; Anac, H.; Alsan, S.; Erk, S.

1991-01-01

Nowadays, various digital methods making use of microcomputers for neutron detector signals and determining the reactivity by numerical calculations are used in reactor control systems in place of classical reactivity meters. In this work, a calculation based on the ''The Time Dependent Transport Equation'' has been developed for determining the reactivity numerically. The reactivity values have been obtained utilizing a computer-based data acquisition and control system and compared with the analog reactivity meter values as well as the values calculated from the ''Inhour Equation''

Automated borehole gravity meter system

International Nuclear Information System (INIS)

Lautzenhiser, Th.V.; Wirtz, J.D.

1984-01-01

An automated borehole gravity meter system for measuring gravity within a wellbore. The gravity meter includes leveling devices for leveling the borehole gravity meter, displacement devices for applying forces to a gravity sensing device within the gravity meter to bring the gravity sensing device to a predetermined or null position. Electronic sensing and control devices are provided for (i) activating the displacement devices, (ii) sensing the forces applied to the gravity sensing device, (iii) electronically converting the values of the forces into a representation of the gravity at the location in the wellbore, and (iv) outputting such representation. The system further includes electronic control devices with the capability of correcting the representation of gravity for tidal effects, as well as, calculating and outputting the formation bulk density and/or porosity

A simple reactivity-meter system

International Nuclear Information System (INIS)

Ferreira, P.S.B.

1992-01-01

This paper describes a new version of a reactivity meter developed at the Institute of Nuclear Energy Research (IPEN) (Brazil). The reactivity meter computes the reactor reactivity utilizing a programmable electrometer that performs the data aquisition. The software commands the main functions of the electrometer, the data acquisition, data transfer, and reactivity calculation. The necessary hardware for this reactivity meter are a programmable electrometer, a microcomputer, and interfaces for the microcomputer to communicate with the electrometer. If it is necessary, it is possible to connect a graphic register to the microcomputer. With this conventional hardware, available in any nuclear reactor facility, one can build a powerful reactivity meter. Adding to these advantages, one can use the microcomputer on-line to analyze the data, store the data on diskettes, or create graphics

MULTICHANNEL DISTRIBUTION METER: A VERITABLE ...

African Journals Online (AJOL)

eobe

Usually, commercial home owners preferred the installation of one or few .... communication (GSM) based solution were presented. The authors ... meters. The proposed meters in their work uses .... The most probable data entry component to ...

Attenuation of a non-parallel beam of gamma radiation by thick shielding-application to the determination of the 235U enrichment with NaI detectors

International Nuclear Information System (INIS)

Mortreau, Patricia; Berndt, Reinhard

2005-01-01

The traditional method used to determine the Uranium enrichment by nondestructive analysis is based on the 'enrichment meter principle' [1]. It involves measuring the intensity of the 186 keV net peak area of 235 U in 'quasi-infinite' samples. A prominent factor, which affects the peak intensity, is the presence of gamma absorbing material (e.g., container wall, detector cover) between the sample and the detector. Its effect is taken into consideration in a commonly called 'wall thickness' correction factor. Often calculated on the basis of approximations, its performance is adequate for small attenuation factors applicable to the case of narrow beams. However these approximations do not lead to precise results when wide non-parallel beams are attenuated through thick container walls. This paper is dedicated to the calculation by numerical integration of the geometrical correction factor (K wtc ) which describes the effective mean path length of the radiation through the absorbing layer. This factor was calculated as a function of various measurement parameters (types and dimensions of the detector, of the collimator and of the shielding) for the most commonly used collimator shapes and detectors. Both coherent scattering (Rayleigh) and incoherent scattering (Compton) are taken into account for the calculation of the radiation interaction within the detector

Hydro Ottawa achieves Smart Meter milestone

International Nuclear Information System (INIS)

Anon.

2008-01-01

As Ontario's second largest municipal electricity company, Hydro Ottawa serves more than 285,000 residential and business customers in the city of Ottawa and the village of Casselman. Since 2006, the utility has installed more than 230,000 Smart Meters throughout its service territory in an effort to provide better services to its customers. This initiative represents the largest operational advanced metering infrastructure network in Canada. This move was necessary before time-of-use rates can be implemented in Ottawa. The Smart Meters deliver data wirelessly to Hydro Ottawa's Customer Information System for billing and eliminating manual readings. The Smart Meters are designed to promote more efficient use of electricity. The Government of Ontario has passed legislation requiring the installation of Smart Meters throughout the province by the end of 2010

Technical and economic aspects of new gaseous diffusion uranium enrichment capacity

International Nuclear Information System (INIS)

Langley, R.A. Jr.; O'Donnell, A.J.

1977-01-01

Work is well advanced on design and construction of the next major increment of U.S. uranium enrichment capacity. The plant will use the gaseous diffusion process to provide the required capacity and reliability at a competitive enrichment services cost. Gaseous diffusion technology is the base against which other processes are compared in order to assess their commercial viability. While it has generally been described as a mature technology with limited future development potential, work on design of the new U.S. plant has resulted in major improvement in plant design with corresponding decreases in plant capacity and operating costs. The paper describes major technological advances incorporated into the new plant design and their impact on enrichment costs. These include the effects of: - advanced barrier technology; - tandem compressor drive systems; - optimization of number of equipment sizes; - single level plant design; - development of rapid power level change capability; - electrical system simplification; - plant arrangement and layout. Resulting capital costs and projected enrichment costs are summarized. Enrichment costs are placed in the context of total nuclear fuel cycle costs. Trade-offs between uranium feed material quantities and enrichment plant tails assays are described, and optimization of this aspect of the nuclear fuel cycle is discussed. The effect on enrichment plant characteristics is described. Flexibility and capability of the new U.S. enrichment plant to meet these changing optimization conditions are described

Comparative study of ß-glucan induced respiratory burst measured by nitroblue tetrazolium assay and real-time luminol-enhanced chemiluminescence assay in common carp (Cyprinus carpio L.)

DEFF Research Database (Denmark)

Jiménez, Natalia Ivonne Vera; Pietretti, D.; Wiegertjes, G. F.

2013-01-01

kidney cells of carp. However, whereas the NBT assay was shown to detect the production of only superoxide anions, the real-time luminol-enhanced assay could detect the production of both superoxide anions and hydrogen peroxide. Only the chemiluminescence assay could reliably record the production of ROS......-point measurement based on the intracellular reduction of nitroblue tetrazolium (NBT) and a real-time luminol-enhanced assay based on the detection of native chemiluminescence. Both assays allowed for detection of dose-dependent changes in magnitude of the respiratory burst response induced by β-glucans in head...... on a real-time scale at frequent and continual time intervals for time course experiments, providing more detailed information on the respiratory burst response. The real-time chemiluminescence assay was used to measure respiratory burst activity in macrophage and neutrophilic granulocyte-enriched head...

Oleuropein-Enriched Olive Leaf Extract Affects Calcium Dynamics and Impairs Viability of Malignant Mesothelioma Cells

Directory of Open Access Journals (Sweden)

Carla Marchetti

2015-01-01

Full Text Available Malignant mesothelioma is a poor prognosis cancer in urgent need of alternative therapies. Oleuropein, the major phenolic of olive tree (Olea europaea L., is believed to have therapeutic potentials for various diseases, including tumors. We obtained an oleuropein-enriched fraction, consisting of 60% w/w oleuropein, from olive leaves, and assessed its effects on intracellular Ca2+ and cell viability in mesothelioma cells. Effects of the oleuropein-enriched fraction on Ca2+ dynamics and cell viability were studied in the REN mesothelioma cell line, using fura-2 microspectrofluorimetry and MTT assay, respectively. Fura-2-loaded cells, transiently exposed to the oleuropein-enriched fraction, showed dose-dependent transient elevations of cytosolic Ca2+ concentration (Ca2+i. Application of standard oleuropein and hydroxytyrosol, and of the inhibitor of low-voltage T-type Ca2+ channels NNC-55-0396, suggested that the effect is mainly due to oleuropein acting through its hydroxytyrosol moiety on T-type Ca2+ channels. The oleuropein-enriched fraction and standard oleuropein displayed a significant antiproliferative effect, as measured on REN cells by MTT cell viability assay, with IC50 of 22 μg/mL oleuropein. Data suggest that our oleuropein-enriched fraction from olive leaf extract could have pharmacological application in malignant mesothelioma anticancer therapy, possibly by targeting T-type Ca2+ channels and thereby dysregulating intracellular Ca2+ dynamics.

Biotin Switch Assays for Quantitation of Reversible Cysteine Oxidation.

Science.gov (United States)

Li, R; Kast, J

2017-01-01

Thiol groups in protein cysteine residues can be subjected to different oxidative modifications by reactive oxygen/nitrogen species. Reversible cysteine oxidation, including S-nitrosylation, S-sulfenylation, S-glutathionylation, and disulfide formation, modulate multiple biological functions, such as enzyme catalysis, antioxidant, and other signaling pathways. However, the biological relevance of reversible cysteine oxidation is typically underestimated, in part due to the low abundance and high reactivity of some of these modifications, and the lack of methods to enrich and quantify them. To facilitate future research efforts, this chapter describes detailed procedures to target the different modifications using mass spectrometry-based biotin switch assays. By switching the modification of interest to a biotin moiety, these assays leverage the high affinity between biotin and avidin to enrich the modification. The use of stable isotope labeling and a range of selective reducing agents facilitate the quantitation of individual as well as total reversible cysteine oxidation. The biotin switch assay has been widely applied to the quantitative analysis of S-nitrosylation in different disease models and is now also emerging as a valuable research tool for other oxidative cysteine modifications, highlighting its relevance as a versatile, robust strategy for carrying out in-depth studies in redox proteomics. © 2017 Elsevier Inc. All rights reserved.

Detection of Small Numbers of Campylobacter jejuni and Campylobacter coli Cells in Environmental Water, Sewage, and Food Samples by a Seminested PCR Assay

Science.gov (United States)

Waage, Astrid S.; Vardund, Traute; Lund, Vidar; Kapperud, Georg

1999-01-01

A rapid and sensitive assay was developed for detection of small numbers of Campylobacter jejuni and Campylobacter coli cells in environmental water, sewage, and food samples. Water and sewage samples were filtered, and the filters were enriched overnight in a nonselective medium. The enrichment cultures were prepared for PCR by a rapid and simple procedure consisting of centrifugation, proteinase K treatment, and boiling. A seminested PCR based on specific amplification of the intergenic sequence between the two Campylobacter flagellin genes, flaA and flaB, was performed, and the PCR products were visualized by agarose gel electrophoresis. The assay allowed us to detect 3 to 15 CFU of C. jejuni per 100 ml in water samples containing a background flora consisting of up to 8,700 heterotrophic organisms per ml and 10,000 CFU of coliform bacteria per 100 ml. Dilution of the enriched cultures 1:10 with sterile broth prior to the PCR was sometimes necessary to obtain positive results. The assay was also conducted with food samples analyzed with or without overnight enrichment. As few as ≤3 CFU per g of food could be detected with samples subjected to overnight enrichment, while variable results were obtained for samples analyzed without prior enrichment. This rapid and sensitive nested PCR assay provides a useful tool for specific detection of C. jejuni or C. coli in drinking water, as well as environmental water, sewage, and food samples containing high levels of background organisms. PMID:10103261

Enriched-uranium feed costs for the High-Temperature Gas-Cooled reactor: trends and comparison with other reactor concepts

International Nuclear Information System (INIS)

Thomas, W.E.

1976-04-01

This report discusses each of the components that affect the unit cost for enriched uranium; that is, ore costs, U 3 O 8 to UF 6 conversion cost, costs for enriching services, and changes in transaction tails assay. Historical trends and announced changes are included. Unit costs for highly enriched uranium (93.15 percent 235 U) and for low-enrichment uranium (3.0, 3.2, and 3.5 percent 235 U) are displayed as a function of changes in the above components and compared. It is demonstrated that the trends in these cost components will probably result in significantly less cost increase for highly enriched uranium than for low-enrichment uranium--hence favoring the High-Temperature Gas-Cooled Reactor

Nuclear material enrichment identification method based on cross-correlation and high order spectra

International Nuclear Information System (INIS)

Yang Fan; Wei Biao; Feng Peng; Mi Deling; Ren Yong

2013-01-01

In order to enhance the sensitivity of nuclear material identification system (NMIS) against the change of nuclear material enrichment, the principle of high order statistic feature is introduced and applied to traditional NMIS. We present a new enrichment identification method based on cross-correlation and high order spectrum algorithm. By applying the identification method to NMIS, the 3D graphs with nuclear material character are presented and can be used as new signatures to identify the enrichment of nuclear materials. The simulation result shows that the identification method could suppress the background noises, electronic system noises, and improve the sensitivity against enrichment change to exponential order with no system structure modification. (authors)

Market implications of advanced enrichment techniques

International Nuclear Information System (INIS)

Rougeau, J.-P.

1987-01-01

The only commercial outlet for uranium is for nuclear reactors and the uranium market will be closely linked to the nuclear power market for the forseeable future. Any production cost saving in the uranium cycle clearly, therefore, increases the chances for world-wide expansion of the nuclear industry. Thus, although there is overcapacity in enrichment, development of cheaper, new or more efficient established techniques, is important. The atomic vapour laser isotope separation process is considered and discussed against this background. Separative work units are explained for this technique. The problems of integrating laser isotope separation into the fuel cycle are discussed. The effects on the amount of natural uranium required for different recycling strategies, and for different laser tails assay and time schedules are illustrated. Over the next twenty years laser-based enrichment will have an important effect on the fuel cycle industry. COGEMA is expected to play a part in developing these new techniques. (U.K.)

Method for semi-automated microscopy of filtration-enriched circulating tumor cells.

Science.gov (United States)

Pailler, Emma; Oulhen, Marianne; Billiot, Fanny; Galland, Alexandre; Auger, Nathalie; Faugeroux, Vincent; Laplace-Builhé, Corinne; Besse, Benjamin; Loriot, Yohann; Ngo-Camus, Maud; Hemanda, Merouan; Lindsay, Colin R; Soria, Jean-Charles; Vielh, Philippe; Farace, Françoise

2016-07-14

Circulating tumor cell (CTC)-filtration methods capture high numbers of CTCs in non-small-cell lung cancer (NSCLC) and metastatic prostate cancer (mPCa) patients, and hold promise as a non-invasive technique for treatment selection and disease monitoring. However filters have drawbacks that make the automation of microscopy challenging. We report the semi-automated microscopy method we developed to analyze filtration-enriched CTCs from NSCLC and mPCa patients. Spiked cell lines in normal blood and CTCs were enriched by ISET (isolation by size of epithelial tumor cells). Fluorescent staining was carried out using epithelial (pan-cytokeratins, EpCAM), mesenchymal (vimentin, N-cadherin), leukocyte (CD45) markers and DAPI. Cytomorphological staining was carried out with Mayer-Hemalun or Diff-Quik. ALK-, ROS1-, ERG-rearrangement were detected by filter-adapted-FISH (FA-FISH). Microscopy was carried out using an Ariol scanner. Two combined assays were developed. The first assay sequentially combined four-color fluorescent staining, scanning, automated selection of CD45(-) cells, cytomorphological staining, then scanning and analysis of CD45(-) cell phenotypical and cytomorphological characteristics. CD45(-) cell selection was based on DAPI and CD45 intensity, and a nuclear area >55 μm(2). The second assay sequentially combined fluorescent staining, automated selection of CD45(-) cells, FISH scanning on CD45(-) cells, then analysis of CD45(-) cell FISH signals. Specific scanning parameters were developed to deal with the uneven surface of filters and CTC characteristics. Thirty z-stacks spaced 0.6 μm apart were defined as the optimal setting, scanning 82 %, 91 %, and 95 % of CTCs in ALK-, ROS1-, and ERG-rearranged patients respectively. A multi-exposure protocol consisting of three separate exposure times for green and red fluorochromes was optimized to analyze the intensity, size and thickness of FISH signals. The semi-automated microscopy method reported here

Intelligent Metering for Urban Water: A Review

OpenAIRE

Rodney Stewart; Stuart White; Candice Moy; Ariane Liu; Pierre Mukheibir; Damien Giurco; Thomas Boyle

2013-01-01

This paper reviews the drivers, development and global deployment of intelligent water metering in the urban context. Recognising that intelligent metering (or smart metering) has the potential to revolutionise customer engagement and management of urban water by utilities, this paper provides a summary of the knowledge-base for researchers and industry practitioners to ensure that the technology fosters sustainable urban water management. To date, roll-outs of intelligent metering have been ...

A two-hybrid assay to study protein interactions within the secretory pathway.

Directory of Open Access Journals (Sweden)

Danielle H Dube

Full Text Available Interactions of transcriptional activators are difficult to study using transcription-based two-hybrid assays due to potent activation resulting in false positives. Here we report the development of the Golgi two-hybrid (G2H, a method that interrogates protein interactions within the Golgi, where transcriptional activators can be assayed with negligible background. The G2H relies on cell surface glycosylation to report extracellularly on protein-protein interactions occurring within the secretory pathway. In the G2H, protein pairs are fused to modular domains of the reporter glycosyltransferase, Och1p, and proper cell wall formation due to Och1p activity is observed only when a pair of proteins interacts. Cells containing interacting protein pairs are identified by selectable phenotypes associated with Och1p activity and proper cell wall formation: cells that have interacting proteins grow under selective conditions and display weak wheat germ agglutinin (WGA binding by flow cytometry, whereas cells that lack interacting proteins display stunted growth and strong WGA binding. Using this assay, we detected the interaction between transcription factor MyoD and its binding partner Id2. Interfering mutations along the MyoD:Id2 interaction interface ablated signal in the G2H assay. Furthermore, we used the G2H to detect interactions of the activation domain of Gal4p with a variety of binding partners. Finally, selective conditions were used to enrich for cells encoding interacting partners. The G2H detects protein-protein interactions that cannot be identified via traditional two-hybrid methods and should be broadly useful for probing previously inaccessible subsets of the interactome, including transcriptional activators and proteins that traffic through the secretory pathway.

In Vitro Antimicrobial Assay Of Plants Used In Traditional Medicine ...

African Journals Online (AJOL)

The paper discusses the probable therapeutic basis of these traditional plants based on their secondary metabolite profiles and for the first time draws research attention to Bukoba Rural district as a source for plants with potential pharmaceutical applications. Keywords: Antimicrobial activity, Secondary metabolites, ...

Assessment of Listeria sp. Interference Using a Molecular Assay To Detect Listeria monocytogenes in Food.

Science.gov (United States)

Zittermann, Sandra I; Stanghini, Brenda; See, Ryan Soo; Melano, Roberto G; Boleszczuk, Peter; Murphy, Allana; Maki, Anne; Mallo, Gustavo V

2016-01-01

Detection of Listeria monocytogenes in food is currently based on enrichment methods. When L. monocytogenes is present with other Listeria species in food, the species compete during the enrichment process. Overgrowth competition of the nonpathogenic Listeria species might result in false-negative results obtained with the current reference methods. This potential issue was noted when 50 food samples artificially spiked with L. monocytogenes were tested with a real-time PCR assay and Canada's current reference method, MFHPB-30. Eleven of the samples studied were from foods naturally contaminated with Listeria species other than those used for spiking. The real-time PCR assay detected L. monocytogenes in all 11 of these samples; however, only 6 of these samples were positive by the MFHPB-30 method. To determine whether L. monocytogenes detection can be affected by other species of the same genus due to competition, an L. monocytogenes strain and a Listeria innocua strain with a faster rate of growth in the enrichment broth were artificially coinoculated at different ratios into ground pork meat samples and cultured according to the MFHPB-30 method. L. monocytogenes was detected only by the MFHPB-30 method when L. monocytogenes/L. innocua ratios were 6.0 or higher. In contrast, using the same enrichments, the real-time PCR assay detected L. monocytogenes at ratios as low as 0.6. Taken together, these findings support the hypothesis that L. monocytogenes can be outcompeted by L. innocua during the MFHPB-30 enrichment phase. However, more reliable detection of L. monocytogenes in this situation can be achieved by a PCR-based method mainly because of its sensitivity.

Ambiguity effects of rhyme and meter.

Science.gov (United States)

Wallot, Sebastian; Menninghaus, Winfried

2018-04-23

Previous research has shown that rhyme and meter-although enhancing prosodic processing ease and memorability-also tend to make semantic processing more demanding. Using a set of rhymed and metered proverbs, as well as nonrhymed and nonmetered versions of these proverbs, the present study reveals this hitherto unspecified difficulty of comprehension to be specifically driven by perceived ambiguity. Roman Jakobson was the 1st to propose this hypothesis, in 1960. He suggested that "ambiguity is an intrinsic, inalienable feature" of "parallelistic" diction of which the combination of rhyme and meter is a pronounced example. Our results show that ambiguity indeed explains a substantial portion of the rhyme- and meter-driven difficulty of comprehension. Longer word-reading times differentially reflected ratings for ambiguity and comprehension difficulty. However, the ambiguity effect is not "inalienable." Rather, many rhymed and metered sentences turned out to be low in ambiguity. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Properties of cellulose triacetate dose meter

International Nuclear Information System (INIS)

Tamura, N.; Tanaka, R.; Mitomo, S.; Matsuda, K.; Nagai, S.

1981-01-01

Several clear plastics and dyed plastics are commercially available for dosimetry in intense radiation field, especially for radiation processing applications. Among these dose meters cellulose triacetate (CTA) dose meter has two advantages for routine uses; (1) it has linear response in mega-rad dose region and (2) the main product form is long tape. However, the manufacture of Numelec CTA film so far used had been discontinued, and for this reason we developed a new film for dosimetry uses. To determine the manufacturing conditions of the film, we examined the influence of additives, triphenylphosphate (TPP) and others, and film thickness on the dosimetric properties, since these two conditions remarkably influence the sensitivity of the dose meter. It is necessary for the reliability of plastic dose meters that the radiation induced colorations should be understood as radiation chemical processes. In this paper we describe the determination of the manufacturing conditions of the new film, the feature of the new dose meter, and the coloration mechanism. (author)

39 CFR 501.15 - Computerized Meter Resetting System.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Computerized Meter Resetting System. 501.15... AND DISTRIBUTE POSTAGE EVIDENCING SYSTEMS § 501.15 Computerized Meter Resetting System. (a) Description. The Computerized Meter Resetting System (CMRS) permits customers to reset their postage meters at...

A Probabilistic Model of Meter Perception: Simulating Enculturation

Directory of Open Access Journals (Sweden)

Bastiaan van der Weij

2017-05-01

Full Text Available Enculturation is known to shape the perception of meter in music but this is not explicitly accounted for by current cognitive models of meter perception. We hypothesize that the induction of meter is a result of predictive coding: interpreting onsets in a rhythm relative to a periodic meter facilitates prediction of future onsets. Such prediction, we hypothesize, is based on previous exposure to rhythms. As such, predictive coding provides a possible explanation for the way meter perception is shaped by the cultural environment. Based on this hypothesis, we present a probabilistic model of meter perception that uses statistical properties of the relation between rhythm and meter to infer meter from quantized rhythms. We show that our model can successfully predict annotated time signatures from quantized rhythmic patterns derived from folk melodies. Furthermore, we show that by inferring meter, our model improves prediction of the onsets of future events compared to a similar probabilistic model that does not infer meter. Finally, as a proof of concept, we demonstrate how our model can be used in a simulation of enculturation. From the results of this simulation, we derive a class of rhythms that are likely to be interpreted differently by enculturated listeners with different histories of exposure to rhythms.

Gamma techniques for IAEA [International Atomic Energy Agency] safeguards at centrifuge enrichment cascades

International Nuclear Information System (INIS)

Aaldijk, J.K.; de Betue, P.A.C.; van der Meer, K.; Harry, R.J.S.

1987-01-01

On February 4, 1983, the Hexapartite Safeguards Project (HSP) concluded that the safeguards approach involving limited frequency unannounced access (LFUA) by International Atomic Energy Agency (IAEA) inspectors to cascades areas together with inspection activities outside the cascade areas meets the IAEA safeguards objectives in an effective and efficient way. In this way, the risks of revealing sensitive information were also minimized. The approach has been defined clearly and unambiguously, and it should be applied equally to all technology holders. One of the conclusions of the HSP was that a nondestructive assay go/no-go technique should be used during the LFUA inspections in the cascade areas of centrifuge enrichment plants. The purpose is to verify that the enrichment of the product UF 6 gas is in the range of low-enriched uranium (LEU), i.e., the enrichment is below 20%

Radiofrequency energy exposure from the Trilliant smart meter.

Science.gov (United States)

Foster, Kenneth R; Tell, Richard A

2013-08-01

This paper reviews radiofrequency (RF) field levels produced by electric utility meters equipped with RF transceivers (so-called Smart Meters), focusing on meters from one manufacturer (Trilliant, Redwood City, CA, USA, and Granby, QC, Canada). The RF transmission levels are summarized based on publicly available data submitted to the U.S. Federal Communications Commission supplemented by limited independent measurements. As with other Smart Meters, this meter incorporates a low powered radiofrequency transceiver used for a neighborhood mesh network, in the present case using ZigBee-compliant physical and medium access layers, operating in the 2.45 GHz unlicensed band but with a proprietary network architecture. Simple calculations based on a free space propagation model indicate that peak RF field intensities are in the range of 10 mW m or less at a distance of more than 1-2 m from the meters. However, the duty cycle of transmission from the meters is very low (meter that were consistent with data reported by the vendor to the U.S. Federal Communications Commission. Limited measurements conducted in two houses with the meters were unable to clearly distinguish emissions from the meters from the considerable electromagnetic clutter in the same frequency range from other sources, including Wi-Fi routers and, when it was activated, a microwave oven. These preliminary measurements disclosed the difficulties that would be encountered in characterizing the RF exposures from these meters in homes in the face of background signals from other household devices in the same frequency range. An appendix provides an introduction to Smart Meter technology. The RF transmitters in wireless-equipped Smart Meters operate at similar power levels and in similar frequency ranges as many other digital communications devices in common use, and their exposure levels are very far below U.S. and international exposure limits.

Electricity Submetering on the Cheap: Stick-on Electricity Meters

Energy Technology Data Exchange (ETDEWEB)

Lanzisera, Steven; Lorek, Michael; Pister, Kristofer

2014-08-17

We demonstrate a low-cost, 21 x 12 mm prototype Stick-on Electricity Meter (SEM) to replace traditional in-circuit-breaker-panel current and voltage sensors for building submetering. A SEM sensor is installed on the external face of a circuit breaker to generate voltage and current signals. This allows for the computation of real and apparent power as well as capturing harmonics created by non-linear loads. The prototype sensor is built using commercially available components, resulting in a production cost of under $10 per SEM. With no highvoltage install work requiring an electrician, home owners or other individuals can install the system in a few minutes with no safety implications. This leads to an installed system cost that is much lower than traditional submetering technology.. Measurement results from lab characterization as well as a real-world residential dwelling installation are presented, verifying the operation of our proposed SEM sensor. The SEM sensor can resolve breaker power levels below 10W, and it can be used to provide data for non-intrusive load monitoring systems at full sample rate.

Charge Meter

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 4. Charge Meter: Easy Way to Measure Charge and Capacitance: Some Interesting Electrostatic Experiments. M K Raghavendra V Venkataraman. Classroom Volume 19 Issue 4 April 2014 pp 376-390 ...

A Probabilistic Model of Meter Perception: Simulating Enculturation

NARCIS (Netherlands)

van der Weij, B.; Pearce, M.T.; Honing, H.

Enculturation is known to shape the perception of meter in music but this is not explicitly accounted for by current cognitive models of meter perception. We hypothesize that the induction of meter is a result of predictive coding: interpreting onsets in a rhythm relative to a periodic meter

Fast critical assembly safeguards: NDA methods for highly enriched uranium. Summary report, October 1978-September 1979

International Nuclear Information System (INIS)

Bellinger, F.O.; Winslow, G.H.

1980-12-01

Nondestructive assay (NDA) methods, principally passive gamma measurements and active neutron interrogation, have been studied for their safeguards effectiveness and programmatic impact as tools for making inventories of highly enriched uranium fast critical assembly fuel plates. It was concluded that no NDA method is the sole answer to the safeguards problem, that each of those emphasized here has its place in an integrated safeguards system, and that each has minimum facility impact. It was found that the 185-keV area, as determined with a NaI detector, was independent of highly-enriched uranium (HEU) plate irradiation history, though the random neutron driver methods used here did not permit accurate assay of irradiated plates. Containment procedures most effective for accurate assaying were considered, and a particular geometry is recommended for active interrogation by a random driver. A model, pertinent to that geometry, which relates the effects of multiplication and self-absorption, is described. Probabilities of failing to detect that plates are missing are examined

Measuring methods in power metering 2013; Elektrizitaetsmesstechnik 2013

Energy Technology Data Exchange (ETDEWEB)

Kahmann, Martin; Zayer, Peter (eds.)

2012-07-01

The book addresses technical and economic issues of power metering, data communication and data processing. Smart metering is the key issue discussed in all 14 contributions: 1. The perspective of Smart Metering in Europe through 2020; 2. Introduction of Smart Metering in Austria; 3. Metering after the amended EnWG 2011; 4. The FNN project ''MessSystem 2020''; 5. Technological requirements of Smart Grid and Smart Market; 6. DIN Spec 33440 ''Ergonomic Aspects of Smart Grids and Electromobility''; 7. Load management as a key element of energy transition; 8. Added value in Smart Metering as a result of Smart Home applications, 9. The main cost factors of the new metering systems; 10. BSI protection profile: Smart Meter Gateway certification; 11. The influence of new boundary conditions in metering on intercompany processes; 12. Reliable time allotment via internet; 13. Recommendations of the EEG Clearing Authority on metering problems; 14. Outline quality management manual for state-authorized test services for electric power, gas, water, and heat. [German] Dieses Buch richtet seinen Blick sowohl auf technische wie auch auf energiewirtschaftliche Themen rund um das Thema Mess- und Zaehltechnik sowie die inzwischen immer bedeutsamer werdende zugehoerige Datenkommunikations- und Datenverarbeitungstechnik. Eine zunehmende Betrachtung des Smart Metering als einen Teilaspekt des grossen Themas Smart Grid bildet die gemeinsame Klammer um die Beitraege. Die Themen der 14 Beitraege sind: 1. Perspektive Smart Metering in Europa bis 2020; 2. Smart-Meter-Einfuehrung in Oesterreich; 3. Das Messwesen nach der EnWG-Novelle 2011; 4. Das FNN-Projekt ''MessSystem 2020''; 5. Anforderungen durch Smart Grid und Smart Market an die intelligente Messtechnik; 6. DIN Spec 33440 ''Ergonomie-Aspekte zu Smart Grid und Elektromobilitaet''; 7. Lastverschiebung als Baustein der Energiewende; 8. Mehrwerte beim Smart

Automated nondestructive assay system for the measurement of irradiated Rover fuel

International Nuclear Information System (INIS)

Augustson, R.H.; Menlove, H.O.; Smith, D.B.; Bond, A.L.; Durrill, D.C.; Hollowell, W.P.; Bromley, C.P.

1975-01-01

With the termination of the Nuclear Rocket Propulsion (Rover) Program, and associated reactor testing at the Nuclear Rocket Development Station (NRDS), Nevada, plans are progressing to recover the 93 percent enriched uranium contained in irradiated fuel from twenty various test reactors. This fuel is being packaged into 7-cm-dia by 137-cm-long cardboard tubes, using the remote handling facilities (E-MAD Bldg) of NRDS. After packaging, the fuel is shipped to Allied Chemical Corporation, Idaho Falls, Idaho, for uranium recovery. About 4000 tubes will be needed to package and ship the inventory of fuel elements presently at NRDS. This represents a total of approximately 2500 kg of enriched uranium. To complete the accounting records each tube is being nondestructively assayed and records kept on a reactor-by-reactor basis where possible. The assayed values for a reactor are then compared with original input inventory values and discrepancies resolved. The tubes are being assayed by an active neutron interrogation system designed and fabricated by Los Alamos Scientific Laboratory (LASL) and operated by Westinghouse Astronuclear Laboratory (WANL)-Nevada Operations personnel. WANL is the operating contractor in charge of loading and shipping this fuel. (U.S.)

24 CFR 965.401 - Individually metered utilities.

Science.gov (United States)

2010-04-01

... URBAN DEVELOPMENT PHA-OWNED OR LEASED PROJECTS-GENERAL PROVISIONS Individual Metering of Utilities for Existing PHA-Owned Projects § 965.401 Individually metered utilities. (a) All utility service shall be... supplier or through the use of checkmeters, unless: (1) Individual metering is impractical, such as in the...

Metering error quantification under voltage and current waveform distortion

Science.gov (United States)

Wang, Tao; Wang, Jia; Xie, Zhi; Zhang, Ran

2017-09-01

With integration of more and more renewable energies and distortion loads into power grid, the voltage and current waveform distortion results in metering error in the smart meters. Because of the negative effects on the metering accuracy and fairness, it is an important subject to study energy metering combined error. In this paper, after the comparing between metering theoretical value and real recorded value under different meter modes for linear and nonlinear loads, a quantification method of metering mode error is proposed under waveform distortion. Based on the metering and time-division multiplier principles, a quantification method of metering accuracy error is proposed also. Analyzing the mode error and accuracy error, a comprehensive error analysis method is presented which is suitable for new energy and nonlinear loads. The proposed method has been proved by simulation.

Ultrasensitive and Facile Detection of MicroRNA via a Portable Pressure Meter.

Science.gov (United States)

Shi, Lu; Lei, Jing; Zhang, Bei; Li, Baoxin; Yang, Chaoyong James; Jin, Yan

2018-04-18

The upregulation of microRNA (miRNA) is highly related with some kinds of tumor, such as breast, prostate, lung, and pancreatic cancers. Therefore, for an important tumor biomarker, the point-of-care testing (POCT) of miRNA is of significant importance and is in great demand for disease diagnosis and clinical prognoses. Herein, a POCT assay for miRNA detection was developed via a portable pressure meter. Two hairpin DNA probes, H1 and H2, were ingeniously designed and functionalized with magnetic beads (MBs) and platinum nanoparticles (PtNPs), respectively, to form MBs-H1 and PtNPs-H2 complexes. In the presence of target microRNA 21 (miR-21), the cyclic strand displacement reaction (SDR) between MBs-H1 and PtNPs-H2 was triggered to continuously form the MBs-H1/PtNPs-H2 duplex. Owing to the amplification of cyclic SDR, numerous PtNPs were enriched onto the surface of MBs to catalytically decompose H 2 O 2 for the generation of much O 2 . The gas pressure value has a linear relationship with the logarithmic value of miR-21 concentration in the range of 10 fM to 10 pM. The limit of detection is 7.6 fM, which is more sensitive than that in a number of previous reports. Hairpin DNA probes and magnetic separation highly ensured the specificity and reliability. Single-base mutation was easily discriminated, and the detection of miR-21 in the serum sample achieved satisfactory result. Therefore, it offers a reliable POCT strategy for the detection of miRNA, which is of great theoretical and practical importance for POCT clinical diagnostics.

Digital Receiver Phase Meter

Science.gov (United States)

Marcin, Martin; Abramovici, Alexander

2008-01-01

The software of a commercially available digital radio receiver has been modified to make the receiver function as a two-channel low-noise phase meter. This phase meter is a prototype in the continuing development of a phase meter for a system in which radiofrequency (RF) signals in the two channels would be outputs of a spaceborne heterodyne laser interferometer for detecting gravitational waves. The frequencies of the signals could include a common Doppler-shift component of as much as 15 MHz. The phase meter is required to measure the relative phases of the signals in the two channels at a sampling rate of 10 Hz at a root power spectral density measurements in laser metrology of moving bodies. To illustrate part of the principle of operation of the phase meter, the figure includes a simplified block diagram of a basic singlechannel digital receiver. The input RF signal is first fed to the input terminal of an analog-to-digital converter (ADC). To prevent aliasing errors in the ADC, the sampling rate must be at least twice the input signal frequency. The sampling rate of the ADC is governed by a sampling clock, which also drives a digital local oscillator (DLO), which is a direct digital frequency synthesizer. The DLO produces samples of sine and cosine signals at a programmed tuning frequency. The sine and cosine samples are mixed with (that is, multiplied by) the samples from the ADC, then low-pass filtered to obtain in-phase (I) and quadrature (Q) signal components. A digital signal processor (DSP) computes the ratio between the Q and I components, computes the phase of the RF signal (relative to that of the DLO signal) as the arctangent of this ratio, and then averages successive such phase values over a time interval specified by the user.

Profile of World Uranium Enrichment Programs - 2007

International Nuclear Information System (INIS)

Laughter, Mark D.

2007-01-01

of the future, but has yet to be demonstrated commercially. In the early 1980s, six countries developing gas centrifuge technology (United States, United Kingdom, Germany, the Netherlands, Japan, and Australia) along with the International Atomic Energy Agency (IAEA) and the European Atomic Energy Community (EURATOM) began developing effective safeguards techniques for GCEPs. This effort was known as the Hexapartite Safeguards Project (HSP). The HSP had the goal of maximizing safeguards effectiveness while minimizing the cost to the operator and inspectorate, and adopted several recommendations, such as the acceptance of limited-frequency unannounced access (LFUA) inspections in cascade halls, and the use of nondestructive assay (NDA) measurements and tamper-indicating seals. While only the HSP participants initially committed to implementing all the measures of the approach, it has been used as a model for the safeguards applied to GCEPs in additional states. This report provides a snapshot overview of world enrichment capacity in 2007, including profiles of the uranium enrichment programs of individual states. It is based on open-source information, which is dependent on unclassified sources and may therefore not reflect the most recent developments. In addition, it briefly describes some of the safeguards techniques being used at various enrichment plants, including implementation of HSP recommendations

Investigation of Separate Meter-In Separate Meter-Out Control Strategies for Systems with Over Centre Valves

DEFF Research Database (Denmark)

Pedersen, Henrik C.; Andersen, Torben Ole; Hansen, Rico Hjerm

2010-01-01

to overcome this problem, but it typically implies higher energy consumption and/or decreased control performance. With the development of robust sensors and new valve types with separate meter-in, separate meter-out control it is, however, possible to overcome these stability problems in a much more...... intelligent way, also adding increased functionality to the system. The focus of the current paper is therefore on investigation of different control strategies for Separate Meter-In Separate Meter-Out (SMISMO) control of general single axis hydraulic system with a differential cylinder and an over......-centre valve included. The paper first presents a general model of the system considered, which is experimentally verified. This is followed by a discussion of different control strategies and their implications. For each of the control strategies controllers are described, taking into account the dynamics...

Standardization of portable assay instrumentation: the neutron-coincidence tree

International Nuclear Information System (INIS)

Menlove, H.O.

1983-01-01

Standardization of portable neutron assay instrumentation has been achieved by using the neutron coincidence technique as a common basis for a wide range of instruments and applications. The electronics originally developed for the High-Level Neutron Coincidence Counter has been adapted to both passive- and active-assay instrumentation for field verification of bulk plutonium, inventory samples, pellets, powders, nitrates, high-enriched uranium, and materials-testing-reactor, light-water-reactor, and mixed-oxide fuel assemblies. The family of detectors developed at Los Alamos National Laboratory and their performance under in-field conditions are described. 16 figures, 3 tables

Using Online Video Lectures to Enrich Traditional Face-to-Face Courses

Science.gov (United States)

Makarem, Suzanne C.

2015-01-01

University educators need to meet changing needs of the digital generation by integrating technology through online content delivery. Despite the many advantages of online education, a large number of university professors are reluctant to make the transition from traditional-face-to-face lectures to online delivery, mainly due to the time, cost,…

Atomics International fuel fabrication facility and low enrichment program. Part 2

International Nuclear Information System (INIS)

Hassel, H.W.

1993-01-01

Most of you know our company from the last meeting in May in Vienna, so I won't steal your time with explaining and demonstrating the same techniques that we have heard this morning f rom the other speakers. I would just take some words to explain the order of business with highly enriched uranium. NUKEM handles around almost two tons of highly enriched uranium a year and it was necessary to satisfy all the new physical protection philosophies. That means that we have to install storage and safe fabrication sites for a lot of money, 2.5 meter thick concrete walls, and different alarm systems. So just to demonstrate how silly this business is, we have just overcome this for highly enriched uranium, and now we speak about low enriched uranium for which we don't need all of these investments to make this business safe. I would just like to concentrate my words on the status of fabrication and considerations in my company concerning the medium enriched uranium and low enriched uranium. In TABLE I are the different fuel types (see column 1) and then we have the fabrication in column 2; (The reason that I use the blackboard this morning is that I try to demonstrate all the techniques. However, all the speakers before me did this and in theory we are not so far away from each other.) the experience of my company in kg. In column 3 is the irradiation experience of these fuels types. Column 4 shows the studies and calculations made in our company for lower and medium enriched fuels. The preliminary fabrication tests and calculations are in column 5, and in column 6 we have the delivery time for a prototype core in months after UF 6 supply. Column 7 shows the time for the development of specifications including irradiation time in years for 6 and 7, and column 8 is the estimated cost of 6 and 7. There is just one fuel that is not in this summary and that is U-Zr

Using Online Video Lectures to Enrich Traditional Face-to-Face Courses

Directory of Open Access Journals (Sweden)

Suzanne C. Makarem

2015-07-01

Full Text Available University educators need to meet changing needs of the digital generation by integrating technology through online content delivery. Despite the many advantages of online education, a large number of university professors are reluctant to make the transition from traditional-face-to-face lectures to online delivery, mainly due to the time, cost, and technical competence requirements to make this transition, in addition to the lack of beliefs in the legitimacy of online education. This article demonstrates the use of online video lectures to adapt traditional university courses to a blended format. The study is implemented for a School of Business Marketing course. We illustrate a cost-effective and timeefficient way for faculty members to record and share online video lectures with limited training and technical support. Using a student sample from two sections of the same marketing course, the study findings support the use of online video lectures as an effective way to free class time for learner-centred activities, without sacrificing student performance outcomes or course satisfaction.

Smart Metering System for Microgrids

DEFF Research Database (Denmark)

Palacios-Garcia, Emilio; Guan, Yajuan; Savaghebi, Mehdi

2015-01-01

suppliers, but they can also play a big role in the control of the Microgrid since the recorded power and energy profiles can be integrated in energy management systems (EMS). In addition, basic power quality (PQ) disturbance can de detected and reported by some advanced metering systems. Thus, this paper...... will expose an example of Smart Meters integration in a Microgrid scenario, which is the Intelligent Microgrid Lab of Aalborg University (AAU). To do this, first the installation available in the Microgrid Lab will be introduced. Then, three different test scenarios and their respective results...... will be presented, regarding the capabilities of this system and the advantages of integration the Smart Meters information in the Microgrid control....

Low Cost Digital Vibration Meter.

Science.gov (United States)

Payne, W Vance; Geist, Jon

2007-01-01

This report describes the development of a low cost, digital Micro Electro Mechanical System (MEMS) vibration meter that reports an approximation to the RMS acceleration of the vibration to which the vibration meter is subjected. The major mechanical element of this vibration meter is a cantilever beam, which is on the order of 500 µm in length, with a piezoresistor deposited at its base. Vibration of the device in the plane perpendicular to the cantilever beam causes it to bend, which produces a measurable change in the resistance of a piezoresistor. These changes in resistance along with a unique signal-processing scheme are used to determine an approximation to the RMS acceleration sensed by the device.

Robust Meter Network for Water Distribution Pipe Burst Detection

OpenAIRE

Donghwi Jung; Joong Hoon Kim

2017-01-01

A meter network is a set of meters installed throughout a water distribution system to measure system variables, such as the pipe flow rate and pressure. In the current hyper-connected world, meter networks are being exposed to meter failure conditions, such as malfunction of the meter’s physical system and communication system failure. Therefore, a meter network’s robustness should be secured for reliable provision of informative meter data. This paper introduces a multi-objective optimal me...

Nociceptor-Enriched Genes Required for Normal Thermal Nociception

Directory of Open Access Journals (Sweden)

Ken Honjo

2016-07-01

Full Text Available Here, we describe a targeted reverse genetic screen for thermal nociception genes in Drosophila larvae. Using laser capture microdissection and microarray analyses of nociceptive and non-nociceptive neurons, we identified 275 nociceptor-enriched genes. We then tested the function of the enriched genes with nociceptor-specific RNAi and thermal nociception assays. Tissue-specific RNAi targeted against 14 genes caused insensitive thermal nociception while targeting of 22 genes caused hypersensitive thermal nociception. Previously uncategorized genes were named for heat resistance (i.e., boilerman, fire dancer, oven mitt, trivet, thawb, and bunker gear or heat sensitivity (firelighter, black match, eucalyptus, primacord, jet fuel, detonator, gasoline, smoke alarm, and jetboil. Insensitive nociception phenotypes were often associated with severely reduced branching of nociceptor neurites and hyperbranched dendrites were seen in two of the hypersensitive cases. Many genes that we identified are conserved in mammals.

Versatile operation meter for nuclear information

International Nuclear Information System (INIS)

Huang Yong; Xiao Yabin; Wang Shuyuan; Shu Jingfang; Di Shaoliang; Wu Hongbin

1995-01-01

This paper states a low-cost, small-volume, multi-function, reproducible and new model intelligent nuclear electronic meter. It's hardware and Software were detailed and the 137 Cs spectrum with this meter was presented

Smart metering - new possibilities for energy distribution in the mass customer sector; Smart Metering - neue Moeglichkeiten fuer den Energievertrieb im Massenkundenbereich

Energy Technology Data Exchange (ETDEWEB)

Haller, T. [Simon-Kucher aand Partners GmbH, Wien (Austria); Hoffmann, S.O.; Rentschler, M.D. [Simon-Kucher and Partners Strategy and Marketing Consultants GmbH, Bonn (Germany)

2008-06-15

As a result of the liberalisation of gas and electricity metering procedures energy suppliers are more and more turning their attention to innovative and intelligent metering techniques. Smart Metering allows energy suppliers to improve their metering processes while at the same time responding better to their customers' needs. These developments are also opening up new sales opportunities because intelligent meters facilitate the launch of new products in the mass customer sector. There is therefore much in favour of looking at this topic in greater detail.

Quantitative mass spectrometric analysis of glycoproteins combined with enrichment methods.

Science.gov (United States)

Ahn, Yeong Hee; Kim, Jin Young; Yoo, Jong Shin

2015-01-01

Mass spectrometry (MS) has been a core technology for high sensitive and high-throughput analysis of the enriched glycoproteome in aspects of quantitative assays as well as qualitative profiling of glycoproteins. Because it has been widely recognized that aberrant glycosylation in a glycoprotein may involve in progression of a certain disease, the development of efficient analysis tool for the aberrant glycoproteins is very important for deep understanding about pathological function of the glycoprotein and new biomarker development. This review first describes the protein glycosylation-targeting enrichment technologies mainly employing solid-phase extraction methods such as hydrizide-capturing, lectin-specific capturing, and affinity separation techniques based on porous graphitized carbon, hydrophilic interaction chromatography, or immobilized boronic acid. Second, MS-based quantitative analysis strategies coupled with the protein glycosylation-targeting enrichment technologies, by using a label-free MS, stable isotope-labeling, or targeted multiple reaction monitoring (MRM) MS, are summarized with recent published studies. © 2014 The Authors. Mass Spectrometry Reviews Published by Wiley Periodicals, Inc.

Ssemakalu et al., Afr J Tradit Complement Altern Med. (2016) 13(1 ...

African Journals Online (AJOL)

PROF ADEWUNMI

Background: Pterocarpus angolensis (P. angolensis) is a large deciduous tree native to Sub-Saharan ... This tree usually grows to about 16 meters tall, has a dark brown bark and a ... Besides furniture, this tree has traditionally been used to treat diseases and ..... Osteoarthritis in a North Eastern Nigerian Rural Community.

Assaying Auxin Receptor Activity Using SPR Assays with F-Box Proteins and Aux/IAA Degrons.

Science.gov (United States)

Quareshy, Mussa; Uzunova, Veselina; Prusinska, Justyna M; Napier, Richard M

2017-01-01

The identification of TIR1 as an auxin receptor combined with advanced biophysical instrumentation has led to the development of real-time activity assays for auxins. Traditionally, molecules have been assessed for auxinic activity using bioassays, and agrochemical compound discovery continues to be based on "spray and pray" technologies. Here, we describe the methodology behind an SPR-based assay that uses TIR1 and related F-box proteins with surface plasmon resonance spectrometry for rapid compound screening. In addition, methods for collecting kinetic binding data and data processing are given so that they may support programs for rational design of novel auxin ligands.

Proceedings of the 2006 smart metering conference and expo

International Nuclear Information System (INIS)

2006-01-01

Ontario's smart metering program was launched as part of a general demand response management strategy to improve energy conservation in the province. Smart metering will help consumers to control their electricity bills through conservation and demand response, and will allow consumers to better manage their energy consumption and use it more effectively during cheaper, off-peak times of day. Smart metering systems measure how much electricity a customer uses on an hourly basis, and data is transferred daily to local electricity distributors. Toronto Hydro will have close to 200,000 smart meters installed by the end of 2006. By 2010, Toronto will be North America's largest urban centre to have made the full transition to smart metering technology across its entire base. This conference provided an update of Toronto Hydro's smart metering project, as well as details of their demand response program. Presentations were given by a variety of experts in information technology as well as electric power industry leaders North American demand and response metering strategies were reviewed, as well as various initiatives in advanced metering infrastructure (AMI). Security risks associated with smart metering environments were reviewed. An evaluation of the current regulatory environment was presented along with a discussion of smart metering standards and compatibility issues. New metering technologies were presented as well as various associated demand side management tools. Smart metering pilot programs and initiatives were discussed, and best practices in smart metering were evaluated. Twenty-nine presentations were given at the conference, 13 of which have been indexed separately for inclusion in this database. refs., tabs., figs

Use of enriched uranium in Canada's power reactors

International Nuclear Information System (INIS)

Dormuth, K.W.; Jackson, D.P.

2011-01-01

Recent trends in Canadian nuclear power reactor design and proposed development of nuclear power in Canada have indicated the possibility that Canada will break with its tradition of natural uranium fuelled systems, designed for superior neutron economy and, hence, superior uranium utilization. For instance, the Darlington B new reactor project procurement process included three reactor designs, all employing enriched fuel, although a natural uranium reactor design was included at a late stage in the ensuing environmental assessment for the project as an alternative technology. An evaluation of the alternative designs should include an assessment of the environmental implications through the entire fuel cycle, which unfortunately is not required by the environmental assessment process. Examples of comparative environmental implications of the reactor designs throughout the fuel cycle indicate the importance of these considerations when making a design selection. As Canada does not have enrichment capability, a move toward the use of enriched fuel would mean that Canada would be exporting natural uranium and buying back enriched uranium with value added. From a waste management perspective, Canada would need to deal with mill, refinery, and conversion tailings, as well as with the used fuel from its own reactors, while the enrichment supplier would retain depleted uranium with some commercial value. On the basis of reasoned estimates based on publicly available information, it is expected that enrichment in Canada is likely to be more profitable than exporting natural uranium and buying back enriched uranium. Further, on the basis of environmental assessments for enrichment facilities in other countries, it is expected that an environmental assessment of a properly sited enrichment facility would result in approval. (author)

Arduino based radiation survey meter

International Nuclear Information System (INIS)

Rahman, Nur Aira Abd; Lombigit, Lojius; Abdullah, Nor Arymaswati; Azman, Azraf; Dolah, Taufik; Jaafar, Zainudin; Mohamad, Glam Hadzir Patai; Ramli, Abd Aziz Mhd; Zain, Rasif Mohd; Said, Fazila; Khalid, Mohd Ashhar; Taat, Muhamad Zahidee; Muzakkir, Amir

2016-01-01

This paper presents the design of new digital radiation survey meter with LND7121 Geiger Muller tube detector and Atmega328P microcontroller. Development of the survey meter prototype is carried out on Arduino Uno platform. 16-bit Timer1 on the microcontroller is utilized as external pulse counter to produce count per second or CPS measurement. Conversion from CPS to dose rate technique is also performed by Arduino to display results in micro Sievert per hour (μSvhr −1 ). Conversion factor (CF) value for conversion of CPM to μSvhr −1 determined from manufacturer data sheet is compared with CF obtained from calibration procedure. The survey meter measurement results are found to be linear for dose rates below 3500 µSv/hr

Method for semi-automated microscopy of filtration-enriched circulating tumor cells

International Nuclear Information System (INIS)

Pailler, Emma; Oulhen, Marianne; Billiot, Fanny; Galland, Alexandre; Auger, Nathalie; Faugeroux, Vincent; Laplace-Builhé, Corinne; Besse, Benjamin; Loriot, Yohann; Ngo-Camus, Maud; Hemanda, Merouan; Lindsay, Colin R.; Soria, Jean-Charles; Vielh, Philippe; Farace, Françoise

2016-01-01

Circulating tumor cell (CTC)-filtration methods capture high numbers of CTCs in non-small-cell lung cancer (NSCLC) and metastatic prostate cancer (mPCa) patients, and hold promise as a non-invasive technique for treatment selection and disease monitoring. However filters have drawbacks that make the automation of microscopy challenging. We report the semi-automated microscopy method we developed to analyze filtration-enriched CTCs from NSCLC and mPCa patients. Spiked cell lines in normal blood and CTCs were enriched by ISET (isolation by size of epithelial tumor cells). Fluorescent staining was carried out using epithelial (pan-cytokeratins, EpCAM), mesenchymal (vimentin, N-cadherin), leukocyte (CD45) markers and DAPI. Cytomorphological staining was carried out with Mayer-Hemalun or Diff-Quik. ALK-, ROS1-, ERG-rearrangement were detected by filter-adapted-FISH (FA-FISH). Microscopy was carried out using an Ariol scanner. Two combined assays were developed. The first assay sequentially combined four-color fluorescent staining, scanning, automated selection of CD45 − cells, cytomorphological staining, then scanning and analysis of CD45 − cell phenotypical and cytomorphological characteristics. CD45 − cell selection was based on DAPI and CD45 intensity, and a nuclear area >55 μm 2 . The second assay sequentially combined fluorescent staining, automated selection of CD45 − cells, FISH scanning on CD45 − cells, then analysis of CD45 − cell FISH signals. Specific scanning parameters were developed to deal with the uneven surface of filters and CTC characteristics. Thirty z-stacks spaced 0.6 μm apart were defined as the optimal setting, scanning 82 %, 91 %, and 95 % of CTCs in ALK-, ROS1-, and ERG-rearranged patients respectively. A multi-exposure protocol consisting of three separate exposure times for green and red fluorochromes was optimized to analyze the intensity, size and thickness of FISH signals. The semi-automated microscopy method reported here

Determination of reactor fuel burnup using passive neutron assay

International Nuclear Information System (INIS)

Kodeli, I.; Trkov, A.; Najzer, M.; Ertek, C.

1988-01-01

Passive neutron assay (PNA) method was developed to verify the fissile inventory of the irradiated reactor fuels. The characteristics of the method were studied at 'Jozef Stefan' Institute. The dependence of neutron source in the fuel on burnup, cooling time, initial enrichment and specific power were investigated and the accuracy of the method, using available computer codes was estimated. (author)

Turbine flow meter response in two-phase flows

International Nuclear Information System (INIS)

Shim, W.J.; Dougherty, T.J.; Cheh, H.Y.

1996-01-01

The purpose of this paper is to suggest a simple method of calibrating turbine flow meters to measure the flow rates of each phase in a two-phase flow. The response of two 50.8 mm (2 inch) turbine flow meters to air-water, two-phase mixtures flowing vertically in a 57 mm I.D. (2.25 inch) polycarbonate tube has been investigated for both upflow and downflow. The flow meters were connected in series with an intervening valve to provide an adjustable pressure difference between them. Void fractions were measured by two gamma densitometers, one upstream of the flow meters and the other downstream. The output signal of the turbine flow meters was found to depend only on the actual volumetric flow rate of the gas, F G , and liquid, F L , at the location of the flow meter

Automatic ranging circuit for a digital panel meter

International Nuclear Information System (INIS)

Mueller, T.R.; Ross, H.H.

1976-01-01

This invention relates to a range changing circuit that operates in conjunction with a digital panel meter of fixed sensitivity. The circuit decodes the output of the panel meter and uses that information to change the gain of an input amplifier to the panel meter in order to ensure that the maximum number of significant figures is always displayed in the meter. The circuit monitors five conditions in the meter and responds to any of four combinations of these conditions by means of logic elements to carry out the function of the circuit. The system was designed for readout of a fluorescence analyzer for uranium analysis

An indicator cell assay for blood-based diagnostics.

Directory of Open Access Journals (Sweden)

Samuel A Danziger

Full Text Available We have established proof of principle for the Indicator Cell Assay Platform™ (iCAP™, a broadly applicable tool for blood-based diagnostics that uses specifically-selected, standardized cells as biosensors, relying on their innate ability to integrate and respond to diverse signals present in patients' blood. To develop an assay, indicator cells are exposed in vitro to serum from case or control subjects and their global differential response patterns are used to train reliable, disease classifiers based on a small number of features. In a feasibility study, the iCAP detected pre-symptomatic disease in a murine model of amyotrophic lateral sclerosis (ALS with 94% accuracy (p-Value = 3.81E-6 and correctly identified samples from a murine Huntington's disease model as non-carriers of ALS. Beyond the mouse model, in a preliminary human disease study, the iCAP detected early stage Alzheimer's disease with 72% cross-validated accuracy (p-Value = 3.10E-3. For both assays, iCAP features were enriched for disease-related genes, supporting the assay's relevance for disease research.

EU data protection and smart metering. Legal boundary conditions; EU-Datenschutz und Smart Metering. Rechtliche Rahmenbedingungen

Energy Technology Data Exchange (ETDEWEB)

Hladjk, Joerg [Praxisgruppe European Data Protection and Privacy, Hunton and Williams, Bruessel (Belgium)

2011-07-01

With the introduction of smart metering, the problem of data protection arises. The independent Article 29 Data Protection Group of the European Commission drew up an expert opinion with the intention of explaining the applicable EU data protection regulations for the smart metering technology in the power supply sector. (orig.)

Monitoring cyclodextrin-polyviologen pseudopolyrotaxanes with the Bradford assay.

Science.gov (United States)

Belitsky, Jason M; Nelson, Alshakim; Stoddart, J Fraser

2006-01-21

Self-assembled multivalent pseudopolyrotaxanes, composed of lactoside-bearing cyclodextrin (CD) rings threaded on linear polyviologen polymers, have been introduced recently as flexible and dynamic neoglycoconjugates. In the course of this research, it was found that polyviologens are responsive to the Bradford assay, which is traditionally highly selective for proteins. The response of the pseudopolyrotaxanes to the Bradford assay was dependant on, and thus indicative of, the degree of threading of the CD rings onto the polyelectrolyte. The assay was then used to report on the threading and dethreading of native and lactoside-bearing alpha-CD rings onto and off of polyviologen chains, a phenomenon which demonstrates the utility of biochemical assays to address problems unique to supramolecular chemistry.

Your Glucose Meter

Science.gov (United States)

... Medical Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco ... 164KB) En Español Basic Facts 7 Tips for Testing Your Blood Sugar and Caring for Your Meter ...

Arduino based radiation survey meter

Energy Technology Data Exchange (ETDEWEB)

Rahman, Nur Aira Abd, E-mail: nur-aira@nm.gov.my; Lombigit, Lojius; Abdullah, Nor Arymaswati; Azman, Azraf; Dolah, Taufik; Jaafar, Zainudin; Mohamad, Glam Hadzir Patai; Ramli, Abd Aziz Mhd; Zain, Rasif Mohd; Said, Fazila; Khalid, Mohd Ashhar; Taat, Muhamad Zahidee [Malaysian Nuclear Agency, 43000, Bangi, Selangor (Malaysia); Muzakkir, Amir [Sinaran Utama Teknologi Sdn Bhd, 43650, Bandar Baru Bangi, Selangor (Malaysia)

2016-01-22

This paper presents the design of new digital radiation survey meter with LND7121 Geiger Muller tube detector and Atmega328P microcontroller. Development of the survey meter prototype is carried out on Arduino Uno platform. 16-bit Timer1 on the microcontroller is utilized as external pulse counter to produce count per second or CPS measurement. Conversion from CPS to dose rate technique is also performed by Arduino to display results in micro Sievert per hour (μSvhr{sup −1}). Conversion factor (CF) value for conversion of CPM to μSvhr{sup −1} determined from manufacturer data sheet is compared with CF obtained from calibration procedure. The survey meter measurement results are found to be linear for dose rates below 3500 µSv/hr.

Attenuation of a non-parallel beam of gamma radiation by thick shielding-application to the determination of the {sup 235}U enrichment with NaI detectors

Energy Technology Data Exchange (ETDEWEB)

Mortreau, Patricia [European Commission, Joint Research Centre, Institute for the Protection and Security of the Citizen, TP 800 Via Fermi, Ispra (Vatican City State, Holy See,) (Italy)]. E-mail: patricia.mortreau@jrc.it; Berndt, Reinhard [European Commission, Joint Research Centre, Institute for the Protection and Security of the Citizen, TP 800 Via Fermi, Ispra (VA) (Italy)

2005-09-21

The traditional method used to determine the Uranium enrichment by nondestructive analysis is based on the 'enrichment meter principle' [1]. It involves measuring the intensity of the 186 keV net peak area of {sup 235}U in 'quasi-infinite' samples. A prominent factor, which affects the peak intensity, is the presence of gamma absorbing material (e.g., container wall, detector cover) between the sample and the detector. Its effect is taken into consideration in a commonly called 'wall thickness' correction factor. Often calculated on the basis of approximations, its performance is adequate for small attenuation factors applicable to the case of narrow beams. However these approximations do not lead to precise results when wide non-parallel beams are attenuated through thick container walls. This paper is dedicated to the calculation by numerical integration of the geometrical correction factor (K {sub wtc}) which describes the effective mean path length of the radiation through the absorbing layer. This factor was calculated as a function of various measurement parameters (types and dimensions of the detector, of the collimator and of the shielding) for the most commonly used collimator shapes and detectors. Both coherent scattering (Rayleigh) and incoherent scattering (Compton) are taken into account for the calculation of the radiation interaction within the detector.

Measurement of 235U enrichment in UF6 by passive gamma spectrometry

International Nuclear Information System (INIS)

Sawai, Hideo; Ochiai, Ken-ichi; Kaya, Akira

1979-01-01

For the assay of UF 6 , a single-channel analyzer (SCA) system of a passive gamma spectrometer has been developed. Basic measuring conditions were studied: such as the effects of sample density and heterogeneity and the effects of cylinder material and wall thickness. Called ''enrichment analyzer'', the system is operated to carry out the measurement and calculation of 235 U enrichment by a directive of the program in a calculator. The resulting data are available in real time output. Measurements were carried out in two modes: ''all way'' mode which measured in the rotation of the cylinder and the up-and-down motion of the detector, and ''spot'' mode which measured at one point on the cylinder. The average accuracy was about 1.8% in case of the former, and 3.2% in case of the latter. It was shown that the ''all way'' mode is preferable, but the ''spot'' mode is also necessary for the assay of large cylinders such as 30 A type. (J.P.N.)

How today's USM diagnostics solve metering problems[Ultrasonic meters

Energy Technology Data Exchange (ETDEWEB)

Lansing, John

2005-07-01

This paper discusses both basic and advanced diagnostic features of gas ultrasonic meters (USM), and how capabilities built into today's electronics can identify problems that often may not have been identified in the past. It primarily discusses fiscal-quality, multi-path USMs and does not cover issues that may be different with non-fiscal meters. Although USMs basically work the same, the diagnostics for each manufacturer does vary. All brands provide basic features as discussed in AGA 9. However, some provide advanced features that can be used to help identify issues such as blocked flow conditioners and gas compositional errors. This paper is based upon the Daniel USM design and the information presented here may or may not be applicable to other manufacturers. (author) (tk)

De Minimis Thresholds for Federal Building Metering Appropriateness

Energy Technology Data Exchange (ETDEWEB)

Henderson, Jordan W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2015-03-31

The U.S. Department of Energy (DOE) is required by statute and Presidential Memorandum to establish guidelines for agencies to meter their Federal buildings for energy (electricity, natural gas, and steam) and water. See 42 U.S.C. § 8253(e). DOE issued guidance in February 2006 on the installation of electric meters in Federal buildings. A recent update to the 2006 guidance accounts for more current metering practices within the Federal Government. The updated metering guidance specifies that all Federal buildings shall be considered “appropriate” for energy or water metering unless identified for potential exclusion. In developing the updated guidance to carry out the statue, Congress also directed DOE to (among other things) establish exclusions from the metering requirements based on the de minimis quantity of energy use of a Federal building, industrial process, or structure. This paper discusses the method used to identify de minimis values.

Water metering in England and Wales

Directory of Open Access Journals (Sweden)

David Zetland

2016-02-01

Full Text Available The transformation of water services that began with the privatisation of water companies in 1989 extended to households with the implementation of water metering. Meters 'privatised' water and the cost of provision by allocating to individual households costs that had previously been shared within the community. This (ongoing conversion of common pool to private good has mostly improved economic, environmental and social impacts, but the potential burden of metering on poorer households has slowed the transition. Stronger anti-poverty programmes would be better at addressing this poverty barrier than existing coping mechanisms reliant on subsidies from other water consumers.

18 CFR 367.9020 - Account 902, Meter reading expenses.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 902, Meter... GAS ACT Operation and Maintenance Expense Chart of Accounts § 367.9020 Account 902, Meter reading... customer meters, and determining consumption when performed by employees engaged in reading meters. (b...

Smart Metering. Between technical challenge and societal acceptance - Interdisciplinary status quo; Smart Metering. Zwischen technischer Herausforderung und gesellschaftlicher Akzeptanz - Interdisziplinaerer Status Quo

Energy Technology Data Exchange (ETDEWEB)

Westermann, Dirk; Doering, Nicola; Bretschneider, Peter (eds.)

2013-04-01

The international research project RESIDENS (more efficient energy utilization by means of system technical integration of the private ultimate consumer) investigates the technology of smart metering that is the utilization of intelligent smart meters in private households. The interdisciplinary character of the RESIDENS project becomes visible by different sub-projects examining different formulations of a question from perspectives of different scientific disciplines: First of all, chapter 2 of the contribution under consideration follows up the question, what impact the media coverage on smart metering has on the perception of this technology in the population at large. Chapter 3 reports on the state of the art of the smart metering. Chapter 4 illustrates how a load control of private consumers can be performed by means of the smart meter technology. Chapter 5 reports on the impacts of the smart metering on the procurement of energy in the liberalised energy market. Chapter 6 investigates the smart metering from the customer's point of view. Concretely, the user-friendliness of an internet portal is evaluated by which the customers may follow up their consumption of electricity by means of an intelligent smart meter continuously. Chapter 7 illustrates legal aspects of smart metering from the perspective of the customer, electricity suppliers and distribution system operators. Chapter 8 presents the conception and implementation of an online gaming operation for the promotion of competency of private power customers: In line with this game, the participants may learn to handle smart metering and flexible electricity tariffs in an entertaining manner. Finally, chapter 9 reports on an expert interview in which the smart metering technology is evaluated by public utilities being involved in this project.

Multiphase flow metering: 4 years on

Energy Technology Data Exchange (ETDEWEB)

Falcone, G.; Hewitt, G.F.; Alimonti, C.; Harrison, B.

2005-07-01

Since the authors' last review in 2001 [1], the use of Multiphase Flow Metering (MFM) within the oil and gas industry continues to grow apace, being more popular in some parts of the world than others. Since the early 1990's, when the first commercial meters started to appear, there have been more than 1,600 field applications of MFM for field allocation, production optimisation and mobile well testing. As the authors predicted, wet gas metering technology has improved to such an extent that its use has rapidly increased worldwide. A ''who's who'' of the MFM sector is provided, which highlights the mergers in the sector and gives an insight into the meters and measurement principles available today. Cost estimates, potential benefits and reliability in the field of the current MFM technologies are revisited and brought up to date. Several measurements technologies have resurfaced, such as passive acoustic energy patterns, infrared wavelengths, Nuclear Magnetic Resonance (NMR) and Electrical Capacitance Tomography (ECT), and they are becoming commercial. The concept of ''virtual metering'', integrated with ''classical MFM'', is now widely accepted. However, sometimes the principles of the MFM measurements themselves are forgotten, submerged in the sales and marketing hype. (author) (tk)

Micropatterned comet assay enables high throughput and sensitive DNA damage quantification.

Science.gov (United States)

Ge, Jing; Chow, Danielle N; Fessler, Jessica L; Weingeist, David M; Wood, David K; Engelward, Bevin P

2015-01-01

The single cell gel electrophoresis assay, also known as the comet assay, is a versatile method for measuring many classes of DNA damage, including base damage, abasic sites, single strand breaks and double strand breaks. However, limited throughput and difficulties with reproducibility have limited its utility, particularly for clinical and epidemiological studies. To address these limitations, we created a microarray comet assay. The use of a micrometer scale array of cells increases the number of analysable comets per square centimetre and enables automated imaging and analysis. In addition, the platform is compatible with standard 24- and 96-well plate formats. Here, we have assessed the consistency and sensitivity of the microarray comet assay. We showed that the linear detection range for H2O2-induced DNA damage in human lymphoblastoid cells is between 30 and 100 μM, and that within this range, inter-sample coefficient of variance was between 5 and 10%. Importantly, only 20 comets were required to detect a statistically significant induction of DNA damage for doses within the linear range. We also evaluated sample-to-sample and experiment-to-experiment variation and found that for both conditions, the coefficient of variation was lower than what has been reported for the traditional comet assay. Finally, we also show that the assay can be performed using a 4× objective (rather than the standard 10× objective for the traditional assay). This adjustment combined with the microarray format makes it possible to capture more than 50 analysable comets in a single image, which can then be automatically analysed using in-house software. Overall, throughput is increased more than 100-fold compared to the traditional assay. Together, the results presented here demonstrate key advances in comet assay technology that improve the throughput, sensitivity, and robustness, thus enabling larger scale clinical and epidemiological studies. © The Author 2014. Published by

Comparison of five portable peak flow meters

Directory of Open Access Journals (Sweden)

Glaucia Nency Takara

2010-01-01

Full Text Available OBJECTIVE: To compare the measurements of spirometric peak expiratory flow (PEF from five different PEF meters and to determine if their values are in agreement. Inaccurate equipment may result in incorrect diagnoses of asthma and inappropriate treatments. METHODS: Sixty-eight healthy, sedentary and insufficiently active subjects, aged from 19 to 40 years, performed PEF measurements using Air Zone®, Assess®, Galemed®, Personal Best® and Vitalograph® peak flow meters. The highest value recorded for each subject for each device was compared to the corresponding spirometric values using Friedman's test with Dunn's post-hoc (p<0.05, Spearman's correlation test and Bland-Altman's agreement test. RESULTS: The median and interquartile ranges for the spirometric values and the Air Zone®, Assess®, Galemed®, Personal Best® and Vitalograph® meters were 428 (263-688 L/min, 450 (350-800 L/min, 420 (310-720 L/min, 380 (300-735 L/min, 400 (310-685 L/min and 415 (335-610 L/min, respectively. Significant differences were found when the spirometric values were compared to those recorded by the Air Zone® (p<0.001 and Galemed ® (p<0.01 meters. There was no agreement between the spirometric values and the five PEF meters. CONCLUSIONS: The results suggest that the values recorded from Galemed® meters may underestimate the actual value, which could lead to unnecessary interventions, and that Air Zone® meters overestimate spirometric values, which could obfuscate the need for intervention. These findings must be taken into account when interpreting both devices' results in younger people. These differences should also be considered when directly comparing values from different types of PEF meters.

Modification of the BAX System PCR assay for detecting Salmonella in beef, produce, and soy protein isolate. Performance Tested Method 100201.

Science.gov (United States)

Peng, Linda X; Wallace, Morgan; Andaloro, Bridget; Fallon, Dawn; Fleck, Lois; Delduco, Dan; Tice, George

2011-01-01

The BAX System PCR assay for Salmonella detection in foods was previously validated as AOAC Research Institute (RI) Performance Tested Method (PTM) 100201. New studies were conducted on beef and produce using the same media and protocol currently approved for the BAX System PCR assay for E. coli O157:H7 multiplex (MP). Additionally, soy protein isolate was tested for matrix extension using the U.S. Food and Drug Administration-Bacteriological Analytical Manual (FDA-BAM) enrichment protocols. The studies compared the BAX System method to the U.S. Department of Agriculture culture method for detecting Salmonella in beef and the FDA-BAM culture method for detecting Salmonella in produce and soy protein isolate. Method comparison studies on low-level inoculates showed that the BAX System assay for Salmonella performed as well as or better than the reference method for detecting Salmonella in beef and produce in 8-24 h enrichment when the BAX System E. coli O157:H7 MP media was used, and soy protein isolate in 20 h enrichment with lactose broth followed by 3 h regrowth in brain heart infusion broth. An inclusivity panel of 104 Salmonella strains with diverse serotypes was tested by the BAX System using the proprietary BAX System media and returned all positive results. Ruggedness factors involved in the enrichment phase were also evaluated by testing outside the specified parameters, and none of the factors examined affected the performance of the assay.

A Functional Assay for GPR55: Envision Protocol.

Science.gov (United States)

Anavi-Goffer, Sharon; Ross, Ruth A

2016-01-01

AlphaScreen(®) SureFire(®) assay is a novel technology that combines luminescent oxygen channeling technology, nano-beads, and monocloncal antibodies to detect the level of a selected protein in a volume lower than 5 μl. This method is more sensitive compared with the traditional enzyme-linked immunosorbent assays (ELISA), and can detect an increasing number of new targets. Here, we described a method for AlphaScreen(®) SureFire(®) assay that targets ERK1/2 phosphorylation, a primary downstream signaling pathway that conveys activation of GPR55 by L-α-lysophosphatidylinositol (LPI) and certain cannabinoids.

Intelligent Metering for Urban Water: A Review

Directory of Open Access Journals (Sweden)

Rodney Stewart

2013-07-01

Full Text Available This paper reviews the drivers, development and global deployment of intelligent water metering in the urban context. Recognising that intelligent metering (or smart metering has the potential to revolutionise customer engagement and management of urban water by utilities, this paper provides a summary of the knowledge-base for researchers and industry practitioners to ensure that the technology fosters sustainable urban water management. To date, roll-outs of intelligent metering have been driven by the desire for increased data regarding time of use and end-use (such as use by shower, toilet, garden, etc. as well as by the ability of the technology to reduce labour costs for meter reading. Technology development in the water sector generally lags that seen in the electricity sector. In the coming decade, the deployment of intelligent water metering will transition from being predominantly “pilot or demonstration scale” with the occasional city-wide roll-out, to broader mainstream implementation. This means that issues which have hitherto received little focus must now be addressed, namely: the role of real-time data in customer engagement and demand management; data ownership, sharing and privacy; technical data management and infrastructure security, utility workforce skills; and costs and benefits of implementation.

Lipase assay in soils by copper soap colorimetry.

Science.gov (United States)

Saisuburamaniyan, N; Krithika, L; Dileena, K P; Sivasubramanian, S; Puvanakrishnan, R

2004-07-01

A simple and sensitive method for the estimation of lipase activity in soils is reported. In this method, 50mg of soil is incubated with emulsified substrate, the fatty acids liberated are treated with cupric acetate-pyridine reagent, and the color developed is measured at 715 nm. Use of olive oil in this protocol leads to an estimation of true lipase activity in soils. The problem of released fatty acids getting adsorbed onto the soil colloids is obviated by the use of isooctane, and separate standards for different soils need not be developed. Among the various surfactants used for emulsification, polyvinyl alcohol is found to be the most effective. Incubation time of 20 min, soil concentration of 50 mg, pH 6.5, and incubation temperature of 37 degrees C were found to be the most suitable conditions for this assay. During the process of enrichment of the soils with oil, interference by the added oil is avoided by the maintenance of a suitable control, wherein 50 mg of soil is added after stopping the reaction. This assay is sensitive and it could be adopted to screen for lipase producers from enriched soils and oil-contaminated soils before resorting to isolation of the microbes by classical screening methods.

Research on Operation Assessment Method for Energy Meter

Science.gov (United States)

Chen, Xiangqun; Huang, Rui; Shen, Liman; chen, Hao; Xiong, Dezhi; Xiao, Xiangqi; Liu, Mouhai; Xu, Renheng

2018-03-01

The existing electric energy meter rotation maintenance strategy regularly checks the electric energy meter and evaluates the state. It only considers the influence of time factors, neglects the influence of other factors, leads to the inaccuracy of the evaluation, and causes the waste of resources. In order to evaluate the running state of the electric energy meter in time, a method of the operation evaluation of the electric energy meter is proposed. The method is based on extracting the existing data acquisition system, marketing business system and metrology production scheduling platform that affect the state of energy meters, and classified into error stability, operational reliability, potential risks and other factors according to the influencing factors, based on the above basic test score, inspecting score, monitoring score, score of family defect detection. Then, according to the evaluation model according to the scoring, we evaluate electric energy meter operating state, and finally put forward the corresponding maintenance strategy of rotation.

The Achievement of Economically Disadvantaged Fifth Graders in Summer Enrichment Camp

Science.gov (United States)

Boulden, Laurie

2013-01-01

The achievement gap between economically disadvantaged students and their traditional counterparts has continued to be a problem in education. Based on cognitive constructivist theory and enrichment theory, the purpose of this study was to investigate the relationship between scores on a high-stakes achievement test and participation in a summer…

Accuracy of the HumaSensplus point-of-care uric acid meter using capillary blood obtained by fingertip puncture.

Science.gov (United States)

Fabre, Stéphanie; Clerson, Pierre; Launay, Jean-Marie; Gautier, Jean-François; Vidal-Trecan, Tiphaine; Riveline, Jean-Pierre; Platt, Adam; Abrahamsson, Anna; Miner, Jeffrey N; Hughes, Glen; Richette, Pascal; Bardin, Thomas

2018-05-02

The uric acid (UA) level in patients with gout is a key factor in disease management and is typically measured in the laboratory using plasma samples obtained after venous puncture. This study aimed to assess the reliability of immediate UA measurement with capillary blood samples obtained by fingertip puncture with the HumaSens plus point-of-care meter. UA levels were measured using both the HumaSens plus meter in the clinic and the routine plasma UA method in the biochemistry laboratory of 238 consenting diabetic patients. HumaSens plus capillary and routine plasma UA measurements were compared by linear regression, Bland-Altman plots, intraclass correlation coefficient (ICC), and Lin's concordance coefficient. Values outside the dynamic range of the meter, low (LO) or high (HI), were analyzed separately. The best capillary UA thresholds for detecting hyperuricemia were determined by receiver operating characteristic (ROC) curves. The impact of potential confounding factors (demographic and biological parameters/treatments) was assessed. Capillary and routine plasma UA levels were compared to reference plasma UA measurements by liquid chromatography-mass spectrometry (LC-MS) for a subgroup of 67 patients. In total, 205 patients had capillary and routine plasma UA measurements available. ICC was 0.90 (95% confidence interval (CI) 0.87-0.92), Lin's coefficient was 0.91 (0.88-0.93), and the Bland-Altman plot showed good agreement over all tested values. Overall, 17 patients showed values outside the dynamic range. LO values were concordant with plasma values, but HI values were considered uninterpretable. Capillary UA thresholds of 299 and 340 μmol/l gave the best results for detecting hyperuricemia (corresponding to routine plasma UA thresholds of 300 and 360 μmol/l, respectively). No significant confounding factor was found among those tested, except for hematocrit; however, this had a negligible influence on the assay reliability. When capillary and routine

PELATIHAN RENANG GAYA DADA 8 KALI 25 METER 4 SET LEBIH MENINGKATKAN KECEPATAN RENANG 100 METER GAYA DADA DARIPADA 4 KALI 50 METER 4 SET PADA RENANG PEMULA PUTRA

Directory of Open Access Journals (Sweden)

I Wayan Suarta

2013-07-01

Full Text Available Sports pool in Indonesia are well known to the public, which is reduced when driving (after the end of the recovery to begin hand pull another hand, the breaststroke is the style of the most interesting because it does not quickly tiring when compared with other styles, because the process of respiration take place with ease, making them easier use in long-distance swim, at the start to affect the pace to continue this next movement needs to get training and a variety of training models, especially at students aged 10-12 years. Training pool 8 times 25 times 50 meters and 4 meters is one of the training methods that can speed up travel time. The best training model has not been encountered in the data. So do the research to find a model training 25 meter pool 8 times and 4 times 4 sets of 50 meters. The study was conducted with pretest-postes group design. Samples taken from the novice swimmer Toya Ening on Dalung Badung, as many as 26 people were randomly selected simple. Samples were divided into 2 groups each group totaled 13 people. Both groups were equally give training in the first group to pool 8 by 25 feet 4 sets, and 4 times the second group of 4 sets of 50 meters. 0.05 ab. Differences in results were analyzed statistically with  The data analyzed were age, height, weight, leg length and physical fitness.  13.49 seconds.± 107.69, and 126.38 ±The mean test results of the final 100 meter breaststroke swimming in a row 12.14 seconds  F count the results obtained respectively by 0.95 seconds with p = 0.59 and 0.93 seconds with a value of p = 0.34. Data showed significant differences significant (p> 0.05. These results indicate that the training of swimming the breaststroke 8 by 25 feet 4 sets is better than 4 times in 4 sets of 50 meter speed up travel time 100-meter breaststroke swimming novice men (p <0.05. Suggested the use of breaststroke swimming training method 8 by 25 feet 4 sets to be intensified to provide training pool at 100

10 CFR 451.7 - Metering requirements.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Metering requirements. 451.7 Section 451.7 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION RENEWABLE ENERGY PRODUCTION INCENTIVES § 451.7 Metering requirements. The net electric energy generated and sold (kilowatt-hours) by the owner or operator of a qualified...

Validation of Folate-Enriched Eggs as a Functional Food for Improving Folate Intake in Consumers.

Science.gov (United States)

Altic, Leslie; McNulty, Helene; Hoey, Leane; McAnena, Liadhan; Pentieva, Kristina

2016-11-30

Functional foods enriched with folate may be beneficial as a means of optimizing folate status in consumers. We recently developed novel eggs enriched with folate through folic acid supplementation of the hen's feed, but their potential to influence consumer folate status is unknown because the natural folate forms incorporated into the eggs may not necessarily be retained during storage and cooking. This study aimed to determine the stability of natural folates in folate-enriched eggs under typical conditions of storage and cooking. Total folate was determined by microbiological assay following tri-enzyme treatment in folate-enriched eggs and un-enriched (barn and free-range) on the day they were laid, after storage (up to 27 days) and after using four typical cooking methods (boiling, poaching, frying, scrambling) for different durations. On the day of laying, the folate content of enriched eggs was found to be significantly higher than that of un-enriched barn or free-range eggs (mean ± SD; 123.2 ± 12.4 vs. 41.2 ± 2.8 vs. 65.6 ± 18.5 µg/100 g; p functional foods with enriched folate content. Further studies will confirm their effectiveness in optimizing the biomarker folate status of consumers.

A Scalable Smart Meter Data Generator Using Spark

DEFF Research Database (Denmark)

Iftikhar, Nadeem; Liu, Xiufeng; Danalachi, Sergiu

2017-01-01

Today, smart meters are being used worldwide. As a matter of fact smart meters produce large volumes of data. Thus, it is important for smart meter data management and analytics systems to process petabytes of data. Benchmarking and testing of these systems require scalable data, however, it can ...

Multichannel Distribution Meter: A Veritable Solution in Power ...

African Journals Online (AJOL)

Partitioned apartments in commercial buildings particularly in congested environments shares energy supply meters among several users. This often leads to disputes and results to power theft in the form of unpaid bills and meter tampering. This paper described how power from a single supply meter can be adequately ...

Is work-family balance more than conflict and enrichment?

Science.gov (United States)

Carlson, Dawn S; Grzywacz, Joseph G; Zivnuska, Suzanne

2009-10-01

This study deepens our theoretical and practical understanding of work-family balance, defined as the 'accomplishment of role-related expectations that are negotiated and shared between an individual and his/her role-related partners in the work and family domains' (Grzywacz & Carlson, 2007: 458). We develop a new measure of work-family balance and establish discriminant validity between it, work-family conflict, and work-family enrichment. Further, we examine the relationship of work-family balance with six key work and family outcomes. Results suggest that balance explains variance beyond that explained by traditional measures of conflict and enrichment for five of six outcomes tested: job satisfaction, organizational commitment, family satisfaction, family performance, and family functioning. We conclude with a discussion of the applications of our work.

40 CFR 1065.245 - Sample flow meter for batch sampling.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Sample flow meter for batch sampling... Sample flow meter for batch sampling. (a) Application. Use a sample flow meter to determine sample flow... difference between a diluted exhaust sample flow meter and a dilution air meter to calculate raw exhaust flow...

Enriching semantic knowledge bases for opinion mining in big data applications.

Science.gov (United States)

Weichselbraun, A; Gindl, S; Scharl, A

2014-10-01

This paper presents a novel method for contextualizing and enriching large semantic knowledge bases for opinion mining with a focus on Web intelligence platforms and other high-throughput big data applications. The method is not only applicable to traditional sentiment lexicons, but also to more comprehensive, multi-dimensional affective resources such as SenticNet. It comprises the following steps: (i) identify ambiguous sentiment terms, (ii) provide context information extracted from a domain-specific training corpus, and (iii) ground this contextual information to structured background knowledge sources such as ConceptNet and WordNet. A quantitative evaluation shows a significant improvement when using an enriched version of SenticNet for polarity classification. Crowdsourced gold standard data in conjunction with a qualitative evaluation sheds light on the strengths and weaknesses of the concept grounding, and on the quality of the enrichment process.

The relationships between common measures of glucose meter performance.

Science.gov (United States)

Wilmoth, Daniel R

2012-09-01

Glucose meter performance is commonly measured in several different ways, including the relative bias and coefficient of variation (CV), the total error, the mean absolute relative deviation (MARD), and the size of the interval around the reference value that would be necessary to contain a meter measurement at a specified probability. This fourth measure is commonly expressed as a proportion of the reference value and will be referred to as the necessary relative deviation. A deeper understanding of the relationships between these measures may aid health care providers, patients, and regulators in comparing meter performances when different measures are used. The relationships between common measures of glucose meter performance were derived mathematically. Equations are presented for calculating the total error, MARD, and necessary relative deviation using the reference value, relative bias, and CV when glucose meter measurements are normally distributed. When measurements are also unbiased, the CV, total error, MARD, and necessary relative deviation are linearly related and are therefore equivalent measures of meter performance. The relative bias and CV provide more information about meter performance than the other measures considered but may be difficult for some audiences to interpret. Reporting meter performance in multiple ways may facilitate the informed selection of blood glucose meters. © 2012 Diabetes Technology Society.

Wanted: competitive metering infrastructure. Metering must be automated in a high grade; Gesucht: wettbewerbsfaehige Metering-Infrastruktur. Metering muss hochgradig automatisiert werden

Energy Technology Data Exchange (ETDEWEB)

Mueller-Elschner, C. [T-Systems Enterprise Services GmbH, Bonn (Germany). Business Development und Marketing

2008-04-21

Accurate on-time consumption metering and data transmission are increasingly important as energy markets are being deregulated. Measuring and information systems combine measurements with intelligent modules for automatic transmission of consumption information. A meaningful cost-benefit comparision results only when the total system is considered. Telecommunication companies as ICT service systems and service sectors can do a clear contribution to the total system. (orig./GL)

21 CFR 868.1780 - Inspiratory airway pressure meter.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Inspiratory airway pressure meter. 868.1780 Section 868.1780 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... meter. (a) Identification. An inspiratory airway pressure meter is a device used to measure the amount...

Analysis of a quantum nondemolition speed-meter interferometer

International Nuclear Information System (INIS)

Purdue, Patricia

2002-01-01

In the quest to develop viable designs for third-generation optical interferometric gravitational-wave detectors (e.g. LIGO-III and EURO), one strategy is to monitor the relative momentum or speed of the test-mass mirrors rather than monitoring their relative position. This paper describes and analyzes the most straightforward design for a speed meter interferometer that accomplishes this--a design (due to Braginsky, Gorodetsky, Khalili and Thorne) that is analogous to a microwave-cavity speed meter conceived by Braginsky and Khalili. A mathematical mapping between the microwave speed meter and the optical interferometric speed meter is developed and is used to show [in accord with the speed being a quantum nondemolition observable] that in principle the interferometric speed meter can beat the gravitational-wave standard quantum limit (SQL) by an arbitrarily large amount, over an arbitrarily wide range of frequencies, and can do so without the use of squeezed vacuum or any auxiliary filter cavities at the interferometer's input or output. However, in practice, to reach or beat the SQL, this specific speed meter requires exorbitantly high input light power. The physical reason for this is explored, along with other issues such as constraints on performance due to optical dissipation. This analysis forms a foundation for ongoing attempts to develop a more practical variant of an interferometric speed meter and to combine the speed meter concept with other ideas to yield a promising LIGO-III/EURO interferometer design that entails low laser power

Metering in the gas supply sector; Metering in der Gasversorgung

Energy Technology Data Exchange (ETDEWEB)

Wernekinck, U. [RWE Westfalen-Weser-Ems, Recklinghausen (Germany)

2007-10-15

The new conditions of competition in the gas supply sector have strongly increased the requirements on gas grid operators. Mainly an exact gas metering and -accouting will become more and more important. The systems and procedures are presented in detail in this contribution. (GL)

Diesel-Enriched Particulate Matter Functionally Activates Human Dendritic Cells

Science.gov (United States)

Porter, Michael; Karp, Matthew; Killedar, Smruti; Bauer, Stephen M.; Guo, Jia; Williams, D'Ann; Breysse, Patrick; Georas, Steve N.; Williams, Marc A.

2007-01-01

Epidemiologic studies have associated exposure to airborne particulate matter (PM) with exacerbations of asthma. It is unknown how different sources of PM affect innate immunity. We sought to determine how car- and diesel exhaust–derived PM affects dendritic cell (DC) activation. DC development was modeled using CD34+ hematopoietic progenitors. Airborne PM was collected from exhaust plenums of Fort McHenry Tunnel providing car-enriched particles (CEP) and diesel-enriched particles (DEP). DC were stimulated for 48 hours with CEP, DEP, CD40-ligand, or lipopolysaccharide. DC activation was assessed by flow cytometry, enzyme-linked immunosorbent assay, and standard culture techniques. DEP increased uptake of fluorescein isothiocyanate–dextran (a model antigen) by DC. Diesel particles enhanced cell-surface expression of co-stimulatory molecules (e.g., CD40 [P < 0.01] and MHC class II [P < 0.01]). By contrast, CEP poorly affected antigen uptake and expression of cell surface molecules, and did not greatly affect cytokine secretion by DC. However, DEP increased production of TNF, IL-6, and IFN-γ (P < 0.01), IL-12 (P < 0.05), and vascular endothelial growth factor (P < 0.001). In co-stimulation assays of PM-exposed DC and alloreactive CD4+ T cells, both CEP and DEP directed a Th2-like pattern of cytokine production (e.g., enhanced IL-13 and IL-18 and suppressed IFN-γ production). CD4+ T cells were not functionally activated on exposure to either DEP or CEP. Car- and diesel-enriched particles exert a differential effect on DC activation. Our data support the hypothesis that DEP (and to a lesser extent CEP) regulate important functional aspects of human DC, supporting an adjuvant role for this material. PMID:17630318

Smart Metering. Synergies within medium voltage automation; Synergien durch Smart Metering. Automatisierung auf Mittelspannungsebene

Energy Technology Data Exchange (ETDEWEB)

Maas, Peter [IDS GmbH, Ettlingen (Germany)

2010-11-15

Transparent interdivisional system solutions are an indispensable and decisive precondition for the optimization of business processes. The implementation of a Smart Metering solution does not only provide data for billing purposes, but also renders important data for network operation. Synergies can be achieved through the use of a common infrastructure which covers both the needs of Smart Metering and network operation. An open architecture of the solution allows for the future integration of further services of the domains Smart Grid and Smart Home. (orig.)

Calibration of dose meters used in radiotherapy

International Nuclear Information System (INIS)

1979-01-01

This manual is a practical guide, not a comprehensive textbook, to the instrumentation and procedures necessary to calibrate a radiation dose meter used in clinical practice against a secondary standard dose meter

Comparison of five portable peak flow meters.

Science.gov (United States)

Takara, Glaucia Nency; Ruas, Gualberto; Pessoa, Bruna Varanda; Jamami, Luciana Kawakami; Di Lorenzo, Valéria Amorim Pires; Jamami, Mauricio

2010-05-01

To compare the measurements of spirometric peak expiratory flow (PEF) from five different PEF meters and to determine if their values are in agreement. Inaccurate equipment may result in incorrect diagnoses of asthma and inappropriate treatments. Sixty-eight healthy, sedentary and insufficiently active subjects, aged from 19 to 40 years, performed PEF measurements using Air Zone, Assess, Galemed, Personal Best and Vitalograph peak flow meters. The highest value recorded for each subject for each device was compared to the corresponding spirometric values using Friedman's test with Dunn's post-hoc (pmeters were 428 (263-688 L/min), 450 (350-800 L/min), 420 (310-720 L/min), 380 (300-735 L/min), 400 (310-685 L/min) and 415 (335-610 L/min), respectively. Significant differences were found when the spirometric values were compared to those recorded by the Air Zone(R) (pmeters. There was no agreement between the spirometric values and the five PEF meters. The results suggest that the values recorded from Galemed meters may underestimate the actual value, which could lead to unnecessary interventions, and that Air Zone meters overestimate spirometric values, which could obfuscate the need for intervention. These findings must be taken into account when interpreting both devices' results in younger people. These differences should also be considered when directly comparing values from different types of PEF meters.

In-situ calibration of clinical built-in KAP meters with traceability to a primary standard using a reference KAP meter.

Science.gov (United States)

Malusek, A; Helmrot, E; Sandborg, M; Grindborg, J-E; Carlsson, G Alm

2014-12-07

The air kerma-area product (KAP) is used for settings of diagnostic reference levels. The International Atomic Energy Agency (IAEA) recommends that doses in diagnostic radiology (including the KAP values) be estimated with an accuracy of at least ± 7% (k = 2). Industry standards defined by the International Electrotechnical Commission (IEC) specify that the uncertainty of KAP meter measurements should be less than ± 25% (k = 2). Medical physicists willing to comply with the IAEA's recommendation need to apply correction factors to KAP values reported by x-ray units. The aim of this work is to present and evaluate a calibration method for built-in KAP meters on clinical x-ray units. The method is based on (i) a tandem calibration method, which uses a reference KAP meter calibrated to measure the incident radiation, (ii) measurements using an energy-independent ionization chamber to correct for the energy dependence of the reference KAP meter, and (iii) Monte Carlo simulations of the beam quality correction factors that correct for differences between beam qualities at a standard laboratory and the clinic. The method was applied to the KAP meter in a Siemens Aristos FX plus unit. It was found that values reported by the built-in KAP meter differed from the more accurate values measured by the reference KAP meter by more than 25% for high tube voltages (more than 140 kV) and heavily filtered beams (0.3 mm Cu). Associated uncertainties were too high to claim that the IEC's limit of 25% was exceeded. Nevertheless the differences were high enough to justify the need for a more accurate calibration of built-in KAP meters.

Analysing Smart Metering Systems from a Consumer Perspective

Science.gov (United States)

Yesudas, Rani

Many countries are deploying smart meters and Advanced Metering Infrastructure systems as part of demand management and grid modernisation efforts. Several of these projects are facing consumer resistance. The advertised benefits to the consumer appear mainly monetary but detailed analysis shows that financial benefits are hard to realise since the fixed services charges are high. Additionally, the data collected from smart meters have security and privacy implications for the consumer. These projects failed to consider end-users as an important stakeholder group during planning stages resulting in the design and roll-out of expensive systems, which do not demonstrate clear consumer benefits. The overall goal of the research reported in this thesis was to improve the smart metering system to deliver consumer benefits that increase confidence and acceptance of these projects. The smart metering system was examined from an end-user perspective for realistic insights into consumer concerns. Processes from Design Science Research methodology were utilised to conduct this research due to the utilitarian nature of the objective. Consumer segmentation was central to the proposed measures. Initially, a consumer-friendly risk analysis framework was devised, and appropriate requirement elicitation techniques were identified. Control options for smart meter data transfer and storage were explored. Various scenarios were analysed to determine consumer-friendly features in the smart metering system, including control options for smart meter data transfer and storage. Proposed functionalities (billing choices, feedback information and specific configurations to match the needs of different user segments) were studied using the Australian smart metering system. Smart meters vary in capabilities depending on the manufacturer, mode and place of deployment. The research showed that features proposed in this thesis are implementable in smart meters, by examining their applicability

Comparative Analysis of Phenolic Content and Anti oxidative Activities of Eight Malaysian Traditional Vegetables

International Nuclear Information System (INIS)

Nur Huda-Faujan; Zulaikha Abdul Rahim; Maryam Mohamed Rehan; Faujan Ahmad

2015-01-01

Vegetables have been believed to exhibit antioxidant activities due to its phenolic content. Thus, this study was carried out to determine the total phenolic content of water and ethanolic extracts of Malaysian traditional vegetables and assess their antioxidant activities. Eight samples of Malaysian traditional vegetables were dried and extracted its phenolic compounds using water and ethanolic solvent. Total phenolic content of the extracts were compared and evaluated using Folin-Ciocalteu and Prussian Blue reagent. The antioxidant activity were assessed using ferric thiocyanate assay and DPPH free radical scavenging assays. Results found that total phenolic content of water extracts ranged from 7.08 to 14.76 mg GAE (Folin-Ciocalteu assay) and 3.50 to 7.82 mg GAE (Prussian Blue assay). However, the content of phenolic of ethanolic extracts ranged from 5.21 to 15.86 mg GAE (Folin-Ciocalteu assay), and 1.84 to 11.54 mg GAE (Prussian Blue assay). The highest antioxidant activity was observed in water extracts of Etlingera elatior (75.6 %) and ethanolic extracts of Sauropus androgynus (78.1 %). Results also found that the best half maximal inhibitory concentration or IC 50 were demonstrated by water and ethanolic extracts of Sauropus androgynus which demonstrated 0.077 mg/mL and 0.078 mg/ mL, respectively. Hence, this study obtained that most of the Malaysian traditional vegetables have a potential source of natural antioxidant. (author)

Liquid ultrasonic flow meters for crude oil measurement

Energy Technology Data Exchange (ETDEWEB)

Kalivoda, Raymond J.; Lunde, Per

2005-07-01

Liquid ultrasonic flow meters (LUFMs) are gaining popularity for the accurate measurement of petroleum products. In North America the first edition of the API standard ''Measurement of liquid hydrocarbons by ultrasonic flow meters using transit time technology'' was issued in February 2005. It addresses both refined petroleum products and crude oil applications. Its field of application is mainly custody transfer applications but it does provide general guidelines for the installation and operation of LUFM's other applications such as allocation, check meters and leak detection. As with all new technologies performance claims are at times exaggerated or misunderstood and application knowledge is limited. Since ultrasonic meters have no moving parts they appear to have fewer limitations than other liquid flow meters. Liquids ultrasonic flow meters, like turbine meters, are sensitive to fluid properties. It is increasingly more difficult to apply on high viscosity products then on lighter hydrocarbon products. Therefore application data or experience on the measurement of refined or light crude oil may not necessarily be transferred to measuring medium to heavy crude oils. Before better and more quantitative knowledge is available on how LUFMs react on different fluids, the arguments advocating reduced need for in-situ proving and increased dependency on laboratory flow calibration (e.g. using water instead of hydrocarbons) may be questionable. The present paper explores the accurate measurement of crude oil with liquid ultrasonic meters. It defines the unique characteristics of the different API grades of crude oils and how they can affect the accuracy of the liquid ultrasonic measurement. Flow testing results using a new LUFM design are discussed. The paper is intended to provide increased insight into the potentials and limitations of crude oil measurement using ultrasonic flow meters. (author) (tk)

Multiplex target enrichment using DNA indexing for ultra-high throughput SNP detection.

LENUS (Irish Health Repository)

Kenny, Elaine M

2011-02-01

Screening large numbers of target regions in multiple DNA samples for sequence variation is an important application of next-generation sequencing but an efficient method to enrich the samples in parallel has yet to be reported. We describe an advanced method that combines DNA samples using indexes or barcodes prior to target enrichment to facilitate this type of experiment. Sequencing libraries for multiple individual DNA samples, each incorporating a unique 6-bp index, are combined in equal quantities, enriched using a single in-solution target enrichment assay and sequenced in a single reaction. Sequence reads are parsed based on the index, allowing sequence analysis of individual samples. We show that the use of indexed samples does not impact on the efficiency of the enrichment reaction. For three- and nine-indexed HapMap DNA samples, the method was found to be highly accurate for SNP identification. Even with sequence coverage as low as 8x, 99% of sequence SNP calls were concordant with known genotypes. Within a single experiment, this method can sequence the exonic regions of hundreds of genes in tens of samples for sequence and structural variation using as little as 1 μg of input DNA per sample.

Sperm DNA quality evaluated by comet assay and sperm chromatin structure assay in stallions after unilateral orchiectomy.

Science.gov (United States)

Serafini, R; Varner, D D; Bissett, W; Blanchard, T L; Teague, S R; Love, C C

2015-09-15

Unilateral orchiectomy (UO) may interfere with thermoregulation of the remaining testis caused by inflammation surrounding the incision site, thus altering normal spermatogenesis and consequently sperm quality. Two measures of sperm DNA quality (neutral comet assay and the sperm chromatin structure assay [SCSA]) were compared before UO (0 days) and at 14, 30, and 60 days after UO to determine whether sperm DNA changed after a mild testis stress (i.e., UO). The percent DNA in the comet tail was higher at 14 and 60 days compared to 0 days (P comet tail measures (i.e., length, moment, migration) were higher at all time periods after UO compared to 0 days (P comet assay and the SCSA, which was not identified using traditional measures of sperm quality. Copyright © 2015 Elsevier Inc. All rights reserved.

Measurement of highly enriched uranium metal buttons with the high-level neutron coincidence counter operating in the active mode

International Nuclear Information System (INIS)

Foley, J.E.

1980-10-01

The portable High-Level Neutron Coincidence Counter is used in the active mode with the addition of AmLi neutron sources to assay the 235 U content of highly enriched metal pieces or buttons. It is concluded that the portable instrument is a practical instrument for assaying uranium metal buttons with masses in the range 1.5 to 4 kg

Two laboratory methods for the calibration of GPS speed meters

International Nuclear Information System (INIS)

Bai, Yin; Sun, Qiao; Du, Lei; Yu, Mei; Bai, Jie

2015-01-01

The set-ups of two calibration systems are presented to investigate calibration methods of GPS speed meters. The GPS speed meter calibrated is a special type of high accuracy speed meter for vehicles which uses Doppler demodulation of GPS signals to calculate the measured speed of a moving target. Three experiments are performed: including simulated calibration, field-test signal replay calibration, and in-field test comparison with an optical speed meter. The experiments are conducted at specific speeds in the range of 40–180 km h −1 with the same GPS speed meter as the device under calibration. The evaluation of measurement results validates both methods for calibrating GPS speed meters. The relative deviations between the measurement results of the GPS-based high accuracy speed meter and those of the optical speed meter are analyzed, and the equivalent uncertainty of the comparison is evaluated. The comparison results justify the utilization of GPS speed meters as reference equipment if no fewer than seven satellites are available. This study contributes to the widespread use of GPS-based high accuracy speed meters as legal reference equipment in traffic speed metrology. (paper)

Automated Enrichment of Sulfanilamide in Milk Matrices by Utilization of Aptamer-Linked Magnetic Particles.

Science.gov (United States)

Fischer, Christin; Kallinich, Constanze; Klockmann, Sven; Schrader, Jil; Fischer, Markus

2016-12-07

The present work demonstrates the first automated enrichment approach for antibiotics in milk using specific DNA aptamers. First, aptamers toward the antibiotic sulfanilamide were selected and characterized regarding their dissociation constants and specificity toward relevant antibiotics via fluorescence assay and LC-MS/MS detection. The performed enrichment was automated using the KingFisherDuo and compared to a manual approach. Verifying the functionality, trapping was realized in different milk matrices: (i) 0.3% fat milk, (ii) 1.5% fat milk, (iii) 3.5% fat milk, and (iv) 0.3% fat cocoa milk drink. Enrichment factors up to 8-fold could be achieved. Furthermore, it could be shown that novel implementation of a magnetic separator increases the reproducibility and reduces the hands-on time from approximately half a day to 30 min.

Synergisms between smart metering and smart grid; Synergien zwischen Smart Metering und Smart Grid

Energy Technology Data Exchange (ETDEWEB)

Maas, Peter [IDS GmbH, Ettlingen (Germany)

2010-04-15

With the implementation of a smart metering solution, it is not only possible to acquire consumption data for billing but also to acquire relevant data of the distribution grid for grid operation. There is still a wide gap between the actual condition and the target condition. Synergies result from the use of a common infrastructure which takes account both of the requirements of smart metering and of grid operation. An open architecture also enables the future integration of further applications of the fields of smart grid and smart home. (orig.)

Advanced Metering Installations – A Perspective from Federal Sites

Energy Technology Data Exchange (ETDEWEB)

Earni, Shankar [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Technologies Area

2016-05-02

This report is intended to provide guidance to the United States Department of Energy (DOE) and other federal agencies to highlight some of the existing practices related to advanced building metering systems. This study identified some of the existing actions related to advanced meter data and proposes how advanced metered data can be employed to develop robust cost effective measurement and verification (M&V) strategies. This report proposes an integrated framework on how advanced meter data can be used to identify energy conservation opportunities and to develop proactive M&V strategies to ensure that the savings for energy projects are being realized. This information will help improve metering, feedback, and dashboard implementations for reducing energy use at DOE facilities, based on lessons learned from various advanced metering implementations.

Comparison of reverse transcriptase PCR, reverse transcriptase loop-mediated isothermal amplification, and culture-based assays for Salmonella detection from pork processing environments.

Science.gov (United States)

Techathuvanan, Chayapa; Draughon, Frances Ann; D'Souza, Doris Helen

2011-02-01

Novel rapid Salmonella detection assays without the need for sophisticated equipment or labor remain in high demand. Real-time reverse transcriptase PCR (RT-PCR) assays, though rapid and sensitive, require expensive thermocyclers, while a novel RT loop-mediated isothermal amplification (RT-LAMP) method requires only a simple water bath. Our objective was to compare the detection sensitivity of Salmonella Typhimurium from the pork processing environment by RT-LAMP, RT-PCR, and culture-based assays. Carcass and surface swabs and carcass rinses were obtained from a local processing plant. Autoclaved carcass rinses (500 ml) were spiked with Salmonella Typhimurium and filtered. Filters were placed in stomacher bags containing tetrathionate broth (TTB) and analyzed with or without 10-h enrichment at 37 °C. Natural swabs were stomached with buffered peptone water, and natural carcass rinses were filtered, preenriched, and further enriched in TTB. Serially-diluted enriched samples were enumerated by spread plating on xylose lysine Tergitol 4 agar. RNA was extracted from 5 ml of enriched TTB with TRIzol. RT-LAMP assay using previously described invA primers was conducted at 62 °C for 90 min in a water bath with visual detection and by gel electrophoresis. SYBR Green I-based-real-time RT-PCR was carried out with invA primers followed by melt temperature analysis. The results of RT-LAMP detection for spiked carcass rinses were comparable to those of RT-PCR and cultural plating, with detection limits of 1 log CFU/ml, although they were obtained significantly faster, within 24 h including preenrichment and enrichment. RT-LAMP showed 4 of 12 rinse samples positive, while RT-PCR showed 1 of 12 rinse samples positive. For swabs, 6 of 27 samples positive by RT-LAMP and 5 of 27 by RT-PCR were obtained. This 1-day RT-LAMP assay shows promise for routine Salmonella screening by the pork industry. Copyright ©, International Association for Food Protection

FLOW METERS WITH VERY GOOD PERFORMANCES

Directory of Open Access Journals (Sweden)

Mircea Dimitrie CAZACU

2011-11-01

Full Text Available We present the theoretical calculus of a patented flow meter, concerning such the thermodynamic and aerodynamic calculus, as well as the offered precision to measure the flow of the air in any meteorological conditions. In the same time we remark that the proposed flow meter, by its positioning, has not loss of head.

Study of correcting the effect of daughter age on determining 235U enrichment of fuel rods

International Nuclear Information System (INIS)

Deng Jingshan; Zhou Chengfang; Luo Minxuan; Liu Yun

1997-01-01

Gamma-ray passive technique is a very effective method to assay and determine 235 U enrichment of nuclear power plant fuel rods. There is a weakness in this passive method, i.e. only after the uranium isotope daughters of UO 2 pellets have reached to equilibrium with uranium parent, then the 235 U enrichment can be determined. This weakness greatly restricts the application of the method. A new two-peak and two-window technique is developed that can overcome the interference of uranium daughter decay in determining 235 U enrichment of nuclear fuel rods, and the results are very satisfactory. The new technique will play an important role in the gamma-ray passive technique for determining 235 U enrichment of fuel rods. This new technique also makes the gamma-ray passive method perfectly. (11 figs., 6 tabs.)

Enrichment planting without soil treatment

Energy Technology Data Exchange (ETDEWEB)

Hagner, Mats

1998-12-31

Where enrichment planting had been carried out with either of the two species Picea abies and Pinus contorta, the survival of the planted seedlings was at least as good as after planting in a normal clear cut area treated with soil scarification. This was in spite of the fact that the seedlings were placed shallow in the humus layer without any soil treatment. However, they were sheltered from insects by treatment before planting. Where enrichment planting was carried out with Pinus sylvestris the survival in dense forest was poor, but in open forest the survival was good. The growth of planted seedlings was enhanced by traditional clearing and soil treatment. However, this was for Pinus sylvestris not enough to compensate for the loss of time, 1-2 years, caused by arrangement of soil scarification. The growth of seedlings planted under crown cover was directly related to basal area of retained trees. However, the variation in height growth among individual seedlings was very big, which meant that some seedlings grow well also under a fairly dense forest cover. The pioneer species Pinus sylvestris reacted more strongly to basal area of retained trees than did the shade tolerant species Picea abies. Enrichment planting seems to be a necessary tool for preserving volume productivity, at places where fairly intensive harvest of mature trees has been carried out in stands of ordinary forest type in central Sweden. If double seedlings, with one Picea abies and one Pinus sylvestris, are used, the probability for long term establishment is enhanced 13 refs, 20 figs, 4 tabs

Uranium enrichment

International Nuclear Information System (INIS)

1990-01-01

This report looks at the following issues: How much Soviet uranium ore and enriched uranium are imported into the United States and what is the extent to which utilities flag swap to disguise these purchases? What are the U.S.S.R.'s enriched uranium trading practices? To what extent are utilities required to return used fuel to the Soviet Union as part of the enriched uranium sales agreement? Why have U.S. utilities ended their contracts to buy enrichment services from DOE?

Smart Metering: Learning from telecommunication providers. Innovative customized products; Beim Smart Metering von Telekommunikationsanbietern lernen. Innovative Buendelprodukte

Energy Technology Data Exchange (ETDEWEB)

Isbrecht, Volker; Sombrutzki, Ingo [Putz und Partner Unternehmensberatung AG, Hamburg (Germany). Strategie- und Projektmanagement - Energiewirtschaft; Hofer, Kristina [Putz und Partner Unternehmensberatung AG, Hamburg (Germany). CRM- und Telekommunikation

2010-04-06

Deregulation in the electricity and gas metering has raised interest in smart meters. Experts estimate that in a four-person household, smart meters may reduce electricity consumption by up to 10 percent, i.e. 50 - 90 Euros, and CO2 emissions by 8.5 million tonnes, which amounts to 4 percent of the total CO2 emissions in Germany. These are ideal conditions for utilities to develop innovative products for the mass market of private consumers and to improve their competitive standing in the market by a clearly communicated advantage to both the customers and the climate. By utilizing the experience gained in the telecommunications industry, they will be able to respond quickly to impending challenges. (orig.)

Design and Implementation of Enhanced Smart Energy Metering System

Directory of Open Access Journals (Sweden)

Oday A.L.A Ridha

2017-03-01

Full Text Available In this work, the design and implementation of a smart energy metering system has been developed. This system consists of two parts: billing center and a set of distributed smart energy meters. The function of smart energy meter is measuring and calculating the cost of consumed energy according to a multi-tariff scheme. This can be effectively solving the problem of stressing the electrical grid and rising consumer awareness. Moreover, smart energy meter decreases technical losses by improving power factor. The function of the billing center is to issue a consumer bill and contributes in locating the irregularities on the electrical grid (non-technical losses. Moreover, it sends the switch off command in case of the consumer bill is not paid. For implementation of smart energy meter, the microcontroller (PIC 18F45K22 is used. For communication between billing center and smart energy meters, ZigBee technology is adopted. The necessary program for smart energy meter is written in MicroC PRO, while the program for billing center is written in visual C#.

Profile of World Uranium Enrichment Programs-2009

International Nuclear Information System (INIS)

Laughter, Mark D.

2009-01-01

demonstrated commercially. In the early 1980s, six countries developing gas centrifuge technology (United States, United Kingdom, Germany, the Netherlands, Japan, and Australia) along with the International Atomic Energy Agency and the European Atomic Energy Community began developing effective safeguards techniques for GCEPs. This effort was known as the Hexapartite Safeguards Project (HSP). The HSP had the goal of maximizing safeguards effectiveness while minimizing the cost to the operator and inspectorate, and adopted several recommendations, such as the acceptance of limited-frequency unannounced access inspections in cascade halls, and the use of nondestructive assay measurements and tamper-indicating seals. While only the HSP participants initially committed to implementing all the measures of the approach, it has been used as a model for the safeguards applied to GCEPs in additional states. Uranium enrichment capacity has continued to expand on all fronts in the last few years. GCEP capacity is expanding in anticipation of the eventual shutdown of the less-efficient GDPs, the termination of the U.S.-Russia HEU blend-down program slated for 2013, and the possible resurgence of nuclear reactor construction as part of an expected 'Nuclear Renaissance'. Overall, a clear trend in the world profile of uranium enrichment plant operation is the continued movement towards multinational projects driven by commercial and economic interests. Along this vein, the safeguards community is continuing to develop new safeguards techniques and technologies that are not overly burdensome to enrichment plant operators while delivering more effective and efficient results. This report provides a snapshot overview of world enrichment capacity in 2009, including profiles of the uranium enrichment programs of individual states. It is a revision of a 2007 report on the same topic; significant changes in world enrichment programs between the previous and current reports are emphasized. It is

A Prediction-based Smart Meter Data Generator

DEFF Research Database (Denmark)

Iftikhar, Nadeem; Liu, Xiufeng; Nordbjerg, Finn Ebertsen

2016-01-01

With the prevalence of cloud computing and In-ternet of Things (IoT), smart meters have become one of the main components of smart city strategy. Smart meters generate large amounts of fine-grained data that is used to provide useful information to consumers and utility companies for decision......, mainly due to privacy issues. This paper proposes a smart meter data generator that can generate realistic energy consumption data by making use of a small real-world dataset as seed. The generator generates data using a prediction-based method that depends on historical energy consumption patterns along......-making. Now-a-days, smart meter analytics systems consist of analytical algorithms that process massive amounts of data. These analytics algorithms require ample amounts of realistic data for testing and verification purposes. However, it is usually difficult to obtain adequate amounts of realistic data...

Bandwidth Analysis of Smart Meter Network Infrastructure

DEFF Research Database (Denmark)

Balachandran, Kardi; Olsen, Rasmus Løvenstein; Pedersen, Jens Myrup

2014-01-01

Advanced Metering Infrastructure (AMI) is a net-work infrastructure in Smart Grid, which links the electricity customers to the utility company. This network enables smart services by making it possible for the utility company to get an overview of their customers power consumption and also control...... devices in their costumers household e.g. heat pumps. With these smart services, utility companies can do load balancing on the grid by shifting load using resources the customers have. The problem investigated in this paper is what bandwidth require-ments can be expected when implementing such network...... to utilize smart meters and which existing broadband network technologies can facilitate this smart meter service. Initially, scenarios for smart meter infrastructure are identified. The paper defines abstraction models which cover the AMI scenarios. When the scenario has been identified a general overview...

New consumer services provided by smart metering

Directory of Open Access Journals (Sweden)

Daminov Ildar

2015-01-01

Full Text Available This paper focuses on the issues of smart metering market and considers different services provided by smart metering from consumer point of view. Firstly, smart metering deployment challenges emerging and conventional tariffs, which modify a consumer behavior and thus, the entire electric energy market can be optimized since the customer is motivated to consume less energy. Secondly, the authors illustrate changes in electricity quality, which have an impact on consumer relations with utility. Additionally, two main indices of grid resilience – SAIDI and SAIFI – are exemplified to reveal the improvement potential of smart metering implementation in certain regions of Russia that also influence the consumer. Finally, in-home display and privacy problem directly reflect the consumer’s behavior, thus the private life rights should not be violated as they are guaranteed by law.

A neutron dose equivalent meter at CAEP

International Nuclear Information System (INIS)

Tian Shihai; Lu Yan; Wang Heyi; Yuan Yonggang; Chen Xu

2012-01-01

The measurement of neutron dose equivalent has been a widespread need in industry and research. In this paper, aimed at improving the accuracy of neutron dose equivalent meter: a neutron dose counter is simulated with MCNP5, and the energy response curve is optimized. The results show that the energy response factor is from 0.2 to 1.8 for neutrons in the energy range of 2.53×10 -8 MeV to 10 MeV Compared with other related meters, it turns that the design of this meter is right. (authors)

A micro-controller based wide range survey meter

International Nuclear Information System (INIS)

Bhingare, R.R.; Bajaj, K.C.; Kannan, S.

2004-01-01

Wide range survey meters (1μSv/h -10 Sv/h) with the detector(s) mounted at the end of a two-to-four meter-long extendable tube are widely used for radiation protection survey of difficult to reach locations and high dose rate areas, The commercially available survey meters of this type use two GM counters to cover a wide range of dose rate measurement. A new micro-controller based wide range survey meter using two Si diode detectors has been developed. The use of solid state detectors in the survey meter has a number of advantages like low power consumption, lighter battery powered detector probe, elimination of high voltage for the operation of the detectors, etc. The design uses infrared communication between the probe and the readout unit through a light-weight collapsible extension tube for high reliability. The design details and features are discussed in detail. (author)

HJD-I record and analysis meter for nuclear information

International Nuclear Information System (INIS)

Di Shaoliang; Huang Yong; Xiao Yanbin

1992-01-01

A low-cost, small-volume, multi-function and new model intelligent nuclear electronic meter HJD-I Record and Analysis Meter are stated for Nuclear Information. It's hardware and software were detailed and the 137 Cs spectrum with this meter was presented

Adjustment equipment for reactor radioactivity meter

International Nuclear Information System (INIS)

Denisov, V.P.; Malishev, A.N.; Shebanova, L.E.; Kirilyuk, N.A.; Maksimov, Yu.N.; Bessalov, G.G.; Vikhorev, Yu.V.; Lukyanov, M.A.

1978-01-01

An activity meter is described movably located in a channel placed in the peripheral biological shielding of a nuclear reactor. It is connected to a weight moving in a second channel by means of a pulley. This arrangement allows locating the radioactivity meter drive on the outer side of the biological shield and vacating space above the reactor body. (Ha)

The reactivity meter and core reactivity

International Nuclear Information System (INIS)

Siltanen, P.

1999-01-01

This paper discussed in depth the point kinetic equations and the characteristics of the point kinetic reactivity meter, particularly for large negative reactivities. From a given input signal representing the neutron flux seen by a detector, the meter computes a value of reactivity in dollars (ρ/β), based on inverse point kinetics. The prompt jump point of view is emphasised. (Author)

Comparative study on gene set and pathway topology-based enrichment methods.

Science.gov (United States)

Bayerlová, Michaela; Jung, Klaus; Kramer, Frank; Klemm, Florian; Bleckmann, Annalen; Beißbarth, Tim

2015-10-22

Enrichment analysis is a popular approach to identify pathways or sets of genes which are significantly enriched in the context of differentially expressed genes. The traditional gene set enrichment approach considers a pathway as a simple gene list disregarding any knowledge of gene or protein interactions. In contrast, the new group of so called pathway topology-based methods integrates the topological structure of a pathway into the analysis. We comparatively investigated gene set and pathway topology-based enrichment approaches, considering three gene set and four topological methods. These methods were compared in two extensive simulation studies and on a benchmark of 36 real datasets, providing the same pathway input data for all methods. In the benchmark data analysis both types of methods showed a comparable ability to detect enriched pathways. The first simulation study was conducted with KEGG pathways, which showed considerable gene overlaps between each other. In this study with original KEGG pathways, none of the topology-based methods outperformed the gene set approach. Therefore, a second simulation study was performed on non-overlapping pathways created by unique gene IDs. Here, methods accounting for pathway topology reached higher accuracy than the gene set methods, however their sensitivity was lower. We conducted one of the first comprehensive comparative works on evaluating gene set against pathway topology-based enrichment methods. The topological methods showed better performance in the simulation scenarios with non-overlapping pathways, however, they were not conclusively better in the other scenarios. This suggests that simple gene set approach might be sufficient to detect an enriched pathway under realistic circumstances. Nevertheless, more extensive studies and further benchmark data are needed to systematically evaluate these methods and to assess what gain and cost pathway topology information introduces into enrichment analysis. Both

Household Classification Using Smart Meter Data

Directory of Open Access Journals (Sweden)

Carroll Paula

2018-03-01

Full Text Available This article describes a project conducted in conjunction with the Central Statistics Office of Ireland in response to a planned national rollout of smart electricity metering in Ireland. We investigate how this new data source might be used for the purpose of official statistics production. This study specifically looks at the question of determining household composition from electricity smart meter data using both Neural Networks (a supervised machine learning approach and Elastic Net Logistic regression. An overview of both classification techniques is given. Results for both approaches are presented with analysis. We find that the smart meter data alone is limited in its capability to distinguish between household categories but that it does provide some useful insights.

Water velocity meter

Science.gov (United States)

Roberts, C. W.; Smith, D. L.

1970-01-01

Simple, inexpensive drag sphere velocity meter with a zero to 6 ft/sec range measures steady-state flow. When combined with appropriate data acquisition system, it is suited to applications where large numbers of simultaneous measurements are needed for current mapping or velocity profile determination.

Chitosan scaffold modified with D-(+) raffinose and enriched with thiol-modified gelatin for improved osteoblast adhesion

International Nuclear Information System (INIS)

Galli, C; Parisi, L; Smerieri, A; Lumetti, S; Manfredi, E; Macaluso, G M; Elviri, L; Bianchera, A; Bettini, R; Lagonegro, P

2016-01-01

The aim of the present study was to investigate whether chitosan-based scaffolds modified with D-(+) raffinose and enriched with thiol-modified gelatin could selectively improve osteoblast adhesion and proliferation. 2, 3 and 4.5% chitosan films were prepared. Chitosan suitability for tissue engineering was confirmed by protein adsorption assay. Scaffolds were incubated with a 2.5 mg ml −1 BSA solution and the decrease of protein content in the supernatants was measured by spectrophotometry. Chitosan films were then enriched with thiol-modified gelatin and their ability to bind BSA was also measured. Then, 2% chitosan discs with or without thiol-modified gelatin were used as culture substrates for MC3T3-E1 cells. After 72 h cells were stained with trypan blue or with calcein AM and propidium iodide for morphology, viability and proliferation assays. Moreover, cell viability was measured at 48, 72, 96 and 168 h to obtain a growth curve. Chitosan films efficiently bound and retained BSA proportionally to the concentration of chitosan discs. The amount of protein retained was higher on chitosan enriched with thiol-modified gelatin. Moreover, chitosan discs allowed the adhesion and the viability of cells, but inhibited their proliferation. The functionalization of chitosan with thiol-modified gelatin enhanced cell spreading and proliferation. Our data confirm that chitosan is a suitable material for tissue engineering. Moreover, our data show that the enrichment of chitosan with thiol-modified gelatin enhances its biological properties. (paper)

Enrichment behavior and transport mechanism of soil-bound PAHs during rainfall-runoff events.

Science.gov (United States)

Zheng, Yi; Luo, Xiaolin; Zhang, Wei; Wu, Bin; Han, Feng; Lin, Zhongrong; Wang, Xuejun

2012-12-01

Polycyclic Aromatic Hydrocarbons (PAHs) transported by surface runoff result in nonpoint source pollution and jeopardize aquatic ecosystems. The transport mechanism of PAHs during rainfall-runoff events has been rarely studied regarding pervious areas. An experimental system was setup to simulate the runoff pollution process on PAHs-contaminated soil. The enrichment behavior of soil-bound PAHs was investigated. The results show that soil organic matters (SOM), rather than clay particles, seem to be the main carrier of PAHs. The enrichment is highly conditioned on runoff and erosion processes, and its magnitude varies among PAH compounds. It is not feasible to build a simple and universal relationship between enrichment ratio and sediment discharge following the traditional enrichment theory. To estimate the flux of PAHs from pervious areas, soil erosion process has to be clearly understood, and both organic carbon content and composition of SOM should be factored into the calculation. Copyright © 2012 Elsevier Ltd. All rights reserved.

49 CFR 192.359 - Customer meter installations: Operating pressure.

Science.gov (United States)

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Customer meter installations: Operating pressure... SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.359 Customer meter installations: Operating pressure...

Calibration of ionization chamber and GM counter survey meters, (1)

International Nuclear Information System (INIS)

Bingo, Kazuyoshi; Kajimoto, Yoichi; Suga, Shin-ichi

1978-01-01

Three types of ionization chamber survey meters and a type of GM counter survey meter were calibrated for measuring the β-ray absorbed dose rate in a working area. To estimate the β-ray absorbed dose rate, a survey meter was used without and with a filter. A reading of survey meter's indicator measured with the filter was subtracted from a reading measured without the filter, and then the absorbed dose rate was obtained by multiplying this remainder by a conversion coefficient. The conversion coefficients were roughly constant with distance more than 8 cm (ionization chamber survey meters) and with distance more than 5 cm (GM counter survey meter). The conversion coefficient was dependent on β-ray energies. In order to measure the absorbed dose rate of tissue whose epidermal thickness is 40 mg/cm 2 , the constant value, 4 (mrad/h)/(mR/h), was chosen independently of β-ray energies as the conversion coefficient of three types of ionization chamber survey meters. The conversion coefficient of the GM counter survey meter was more energy dependent than that of every type of ionization chamber survey meter. (author)

Multiplex Real-Time PCR for Detection of Staphylococcus aureus, mecA and Panton-Valentine Leukocidin (PVL) Genes from Selective Enrichments from Animals and Retail Meat

Science.gov (United States)

Velasco, Valeria; Sherwood, Julie S.; Rojas-García, Pedro P.; Logue, Catherine M.

2014-01-01

The aim of this study was to compare a real-time PCR assay, with a conventional culture/PCR method, to detect S. aureus, mecA and Panton-Valentine Leukocidin (PVL) genes in animals and retail meat, using a two-step selective enrichment protocol. A total of 234 samples were examined (77 animal nasal swabs, 112 retail raw meat, and 45 deli meat). The multiplex real-time PCR targeted the genes: nuc (identification of S. aureus), mecA (associated with methicillin resistance) and PVL (virulence factor), and the primary and secondary enrichment samples were assessed. The conventional culture/PCR method included the two-step selective enrichment, selective plating, biochemical testing, and multiplex PCR for confirmation. The conventional culture/PCR method recovered 95/234 positive S. aureus samples. Application of real-time PCR on samples following primary and secondary enrichment detected S. aureus in 111/234 and 120/234 samples respectively. For detection of S. aureus, the kappa statistic was 0.68–0.88 (from substantial to almost perfect agreement) and 0.29–0.77 (from fair to substantial agreement) for primary and secondary enrichments, using real-time PCR. For detection of mecA gene, the kappa statistic was 0–0.49 (from no agreement beyond that expected by chance to moderate agreement) for primary and secondary enrichment samples. Two pork samples were mecA gene positive by all methods. The real-time PCR assay detected the mecA gene in samples that were negative for S. aureus, but positive for Staphylococcus spp. The PVL gene was not detected in any sample by the conventional culture/PCR method or the real-time PCR assay. Among S. aureus isolated by conventional culture/PCR method, the sequence type ST398, and multi-drug resistant strains were found in animals and raw meat samples. The real-time PCR assay may be recommended as a rapid method for detection of S. aureus and the mecA gene, with further confirmation of methicillin-resistant S. aureus (MRSA) using

Multiplex real-time PCR for detection of Staphylococcus aureus, mecA and Panton-Valentine Leukocidin (PVL genes from selective enrichments from animals and retail meat.

Directory of Open Access Journals (Sweden)

Valeria Velasco

Full Text Available The aim of this study was to compare a real-time PCR assay, with a conventional culture/PCR method, to detect S. aureus, mecA and Panton-Valentine Leukocidin (PVL genes in animals and retail meat, using a two-step selective enrichment protocol. A total of 234 samples were examined (77 animal nasal swabs, 112 retail raw meat, and 45 deli meat. The multiplex real-time PCR targeted the genes: nuc (identification of S. aureus, mecA (associated with methicillin resistance and PVL (virulence factor, and the primary and secondary enrichment samples were assessed. The conventional culture/PCR method included the two-step selective enrichment, selective plating, biochemical testing, and multiplex PCR for confirmation. The conventional culture/PCR method recovered 95/234 positive S. aureus samples. Application of real-time PCR on samples following primary and secondary enrichment detected S. aureus in 111/234 and 120/234 samples respectively. For detection of S. aureus, the kappa statistic was 0.68-0.88 (from substantial to almost perfect agreement and 0.29-0.77 (from fair to substantial agreement for primary and secondary enrichments, using real-time PCR. For detection of mecA gene, the kappa statistic was 0-0.49 (from no agreement beyond that expected by chance to moderate agreement for primary and secondary enrichment samples. Two pork samples were mecA gene positive by all methods. The real-time PCR assay detected the mecA gene in samples that were negative for S. aureus, but positive for Staphylococcus spp. The PVL gene was not detected in any sample by the conventional culture/PCR method or the real-time PCR assay. Among S. aureus isolated by conventional culture/PCR method, the sequence type ST398, and multi-drug resistant strains were found in animals and raw meat samples. The real-time PCR assay may be recommended as a rapid method for detection of S. aureus and the mecA gene, with further confirmation of methicillin-resistant S. aureus (MRSA

Effects of the leakage magnetic field from an analog meter on the response of scintillation survey meters

International Nuclear Information System (INIS)

Abe, Toshiaki; Yamamoto, Hisao; Norimura, Toshiyuki; Katase, Akira

2003-01-01

Effects of the weak leakage magnetic field are studied on the response of two kinds of scintillation survey meters: an ordinary type for γ-rays and that optimized for the detection of low-energy photons from 125 I. In the presence of the magnetic field, the response of the optimized survey meter decreases to the photons from 125 I, and increases considerably to the background radiations. On the other hand, the response of the ordinary survey meter decreases slightly to both the γ-rays from 131 I and the background radiations. From analysis of the pulse-height spectra for the radiations, such variations of the response are ascribed to the reduction of the amplification factor of photomultiplier tubes by the magnetic field. (author)

49 CFR 192.357 - Customer meters and regulators: Installation.

Science.gov (United States)

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Customer meters and regulators: Installation. 192... SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Customer Meters, Service Regulators, and Service Lines § 192.357 Customer meters and regulators: Installation. (a...

Apparent losses due to domestic water meter under-registration in ...

African Journals Online (AJOL)

By combining these results with the average age of meters in South Africa, estimated from the National Water Demand Archive, it was possible to estimate the average meter under-registration due to meter aging. The study concluded that apparent losses due to water meter under-registration are around 5% of consumption ...

Evaluation of a PCR assay for identification and differentiation of Campylobacter fetus subspecies

DEFF Research Database (Denmark)

Hum, S.; Quinn, K.; Brunner, J.

1997-01-01

methods were attributed to methodological differences used in various laboratories. Conclusion Our results indicate that misidentification of C fetus in routine diagnostic laboratories may be relatively common. The PCR assay evaluated gave rapid and reproducible results and is thus a valuable adjunctive......Objective To evaluate a polymerase chain reaction assay for identification of Campylobacter fetus and differentiation of the defined subspecies. Design Characterisation of bacterial strains by traditional phenotyping, polymerase chain reaction, a probabilistic identification scheme...... by traditional phenotypic methods and the PCR assay was found to be 80.8%. The polymerase chain reaction proved to be a reliable technique for the species and subspecies identification of C fetus; equivocal results were obtained in only two instances. Initial misidentifications by conventional phenotyping...

Herbal distillates: A new era of grape marc distillates with enriched antioxidant profile.

Science.gov (United States)

Andreou, Vasiliki; Strati, Irini F; Fotakis, Charalambos; Liouni, Maria; Zoumpoulakis, Panagiotis; Sinanoglou, Vassilia J

2018-07-01

Grape marc distillates are traditional alcoholic beverages, produced mostly in the Mediterranean countries. The present study proposes the enrichment of a Greek traditional grape marc distillate (tsikoudia) with selected herbs to enhance its natural antioxidants and functional properties. Total phenolic content, the antiradical and antioxidant activities, as well as the phenolic and sugar profiles using NMR and FT-IR spectroscopy were evaluated. The enrichment of distillates with Syzygium aromaticum L., Jasminum officinale L. and Eucalyptus globulus Labill. exhibited the highest total phenolic content as well as the highest antioxidant and antiradical activities, whereas the lowest values were observed with Hippophae rhamnoides L. and Lycium Barbarum Mill. The implementation of NMR and FT-IR spectroscopies attested to the presence of phenolic compounds and of specific carbohydrates in herbal distillates, postulating their migration from selected herbal species to tsikoudia and probably contributing to their organoleptic characteristics. The target of this approach leads to new added-value distillates with enhanced characteristics. Copyright © 2018 Elsevier Ltd. All rights reserved.

Deep subsurface life from North Pond: enrichment, isolation, characterization and genomes of heterotrophic bacteria

Directory of Open Access Journals (Sweden)

Joseph A. Russell

2016-05-01

Full Text Available Studies of subsurface microorganisms have yielded few environmentally relevant isolates for laboratory studies. In order to address this lack of cultivated microorganisms, we initiated several enrichments on sediment and underlying basalt samples from North Pond, a sediment basin ringed by basalt outcrops underlying an oligotrophic water-column west of the Mid-Atlantic Ridge at 22°N. In contrast to anoxic enrichments, growth was observed in aerobic, heterotrophic enrichments from sediment of IODP site U1382B at 4 and 68 meters below seafloor (mbsf. These sediment depths, respectively, correspond to the fringes of oxygen penetration from overlying seawater in the top of the sediment column and upward migration of oxygen from oxic seawater from the basalt aquifer below the sediment. Here we report the enrichment, isolation, and initial characterizations of three isolated aerobic heterotrophs from North Pond sediments; an Arthrobacter species from 4 mbsf, and Paracoccus and Pseudomonas species from 68 mbsf. These cultivated bacteria are represented in the amplicon 16S rRNA gene libraries created from whole sediments, albeit at low (up to 2% relative abundance. We provide genomic evidence from our isolates demonstrating that the Arthrobacter and Pseudomonas isolates have the potential to respire nitrate and oxygen, though dissimilatory nitrate reduction could not be confirmed in laboratory cultures. The cultures from this study represent members of environmentally significant phyla, and allow for further studies into geochemical factors impacting life in the deep subsurface.

40 CFR 92.122 - Smoke meter calibration.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Smoke meter calibration. 92.122 Section 92.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... meter calibration. The smokemeter shall be checked according to the following procedure prior to each...

Integrating an embedded system in a microwave moisture meter

Science.gov (United States)

The conversion of a PC- or laptop-controlled microwave moisture meter to a stand-alone meter hosting its own embedded system is discussed. The moisture meter measures the attenuation and phase shift of low power microwaves traversing the sample, from which the dielectric properties are calculated. T...

A Method of Evaluating Operation of Electric Energy Meter

Science.gov (United States)

Chen, Xiangqun; Li, Tianyang; Cao, Fei; Chu, Pengfei; Zhao, Xinwang; Huang, Rui; Liu, Liping; Zhang, Chenglin

2018-05-01

The existing electric energy meter rotation maintenance strategy regularly checks the electric energy meter and evaluates the state. It only considers the influence of time factors, neglects the influence of other factors, leads to the inaccuracy of the evaluation, and causes the waste of resources. In order to evaluate the running state of the electric energy meter in time, a method of the operation evaluation of the electric energy meter is proposed. The method is based on extracting the existing data acquisition system, marketing business system and metrology production scheduling platform that affect the state of energy meters, and classified into error stability, operational reliability, potential risks and other factors according to the influencing factors, based on the above basic test score, inspecting score, monitoring score, score of family defect detection. Then, according to the evaluation model according to the scoring, we evaluate electric energy meter operating state, and finally put forward the corresponding maintenance strategy of rotation.

Characterization of radiofrequency field emissions from smart meters.

Science.gov (United States)

Tell, Richard A; Kavet, Robert; Mezei, Gabor

2013-01-01

This study presents measurement data that describe radiofrequency emission levels and patterns from smart meters (rated nominally at 1 W) currently deployed in Pacific Gas and Electric Company's service territory in northern California. The smart meters in our investigation could not be set to operate continuously and required a Field Service Unit to induce short periods of emitted fields. To obtain peak field data under both laboratory and ambient conditions, a spectrum analyzer scanned across the 83 transmitting channels between 902 and 928 MHz used by the smart meter on a random frequency-hopping basis. To obtain data describing temporal emission patterns, the analyzer operated in scope mode. Duty cycle was estimated using transmit data acquired by the system operator from over 88,000 m. Instantaneous peak fields at 0.3 m in front of the meters were no more than 15% of the US Federal Communications Commission (FCC) exposure limit for the general public, and 99.9% of the meters operated with a duty cycle of 1.12% or less during the sampling period. In a sample of measurements in six single-detached residences equipped with individual smart meters, no interior measurement of peak field exceeded 1% of the FCC's general public exposure limit.

Development of a VHH-Based Erythropoietin Quantification Assay

DEFF Research Database (Denmark)

Kol, Stefan; Beuchert Kallehauge, Thomas; Adema, Simon

2015-01-01

Erythropoietin (EPO) quantification during cell line selection and bioreactor cultivation has traditionally been performed with ELISA or HPLC. As these techniques suffer from several drawbacks, we developed a novel EPO quantification assay. A camelid single-domain antibody fragment directed against...... human EPO was evaluated as a capturing antibody in a label-free biolayer interferometry-based quantification assay. Human recombinant EPO can be specifically detected in Chinese hamster ovary cell supernatants in a sensitive and pH-dependent manner. This method enables rapid and robust quantification...

Energy saving by smart metering with consumption feedback; Energieeinsparung durch Smart Metering mit Verbrauchs-Feedback

Energy Technology Data Exchange (ETDEWEB)

Hoffmann, Patrick [Institut fuer ZukunftsEnergieSysteme (IZES), Saarbruecken (Germany); Friedrich, Malte [Institut fuer Soziologische Meinungsforschung (IsoMe), Berlin (Germany); Kerber-Clasen, Stefan [Institut fuer Sozialforschung und Sozialwirtschaft e.V., Saarbruecken (Germany); Frey, Guenther

2012-08-15

While the German legislative, e.g. in the EnWG (Power Industry Act) assumes that electricity consumption metering will contribute to energy conservation in any case, many studies have arrived at a different contribution: Only a combination of consumption metering and direct feedback methods will result in significant energy savings. A recent research project (''Moderne Energiesparsysteme fuer Haushalte'') analysed an energy conservation system of this type. The findings will provide socio-economic insight into the background of successful energy conservation, and they will show how feedback methods can be optimised.

Metering: EU policy and implications for fuel poor households

International Nuclear Information System (INIS)

Darby, Sarah J.

2012-01-01

Fuel poverty is a function of household energy consumption, income, and the cost of delivered energy. The paper discusses ways in which current EU policy on the development of ‘smart’ metering could affect fuel poor households. The main focus is on developments in electricity metering and the development of ‘active demand’ and smart grids, so that demand can be matched closely with available supply. Advances in metering and related technologies open the way to time-of-use charging, easier switching between suppliers and between credit payment and prepayment, direct load control of some end-uses by the utility, greater scope for microgeneration, and improved consumption feedback for customers. These options open up both uncertainties and risks. The paper offers definitions and discussion of various functions of smart metering, summarizes the EU policy background, and considers some possible equity implications of rolling out a new generation of meters. There follows an assessment of potential implications to the fuel poor of changes to metering, based on a review of the literature on energy feedback, tariffing, and supplier–customer relationships. Much of the discussion is based on the UK experience, with examples from other EU member states and, where appropriate, from other parts of the world. - Highlights: ► Smart meters are part of general upgrading of electricity and gas networks. ► EU policy is to roll out the meters to 80%+ of the population by 2020. ► Improved feedback and prepayment metering may benefit the fuel poor. ► Remote disconnection and data privacy are issues for all consumers. ► We need careful assessment of potential gains and losses to the fuel poor.

EMMNet: Sensor Networking for Electricity Meter Monitoring

Directory of Open Access Journals (Sweden)

Zhi-Ting Lin

2010-06-01

Full Text Available Smart sensors are emerging as a promising technology for a large number of application domains. This paper presents a collection of requirements and guidelines that serve as a basis for a general smart sensor architecture to monitor electricity meters. It also presents an electricity meter monitoring network, named EMMNet, comprised of data collectors, data concentrators, hand-held devices, a centralized server, and clients. EMMNet provides long-distance communication capabilities, which make it suitable suitable for complex urban environments. In addition, the operational cost of EMMNet is low, compared with other existing remote meter monitoring systems based on GPRS. A new dynamic tree protocol based on the application requirements which can significantly improve the reliability of the network is also proposed. We are currently conducting tests on five networks and investigating network problems for further improvements. Evaluation results indicate that EMMNet enhances the efficiency and accuracy in the reading, recording, and calibration of electricity meters.

EMMNet: sensor networking for electricity meter monitoring.

Science.gov (United States)

Lin, Zhi-Ting; Zheng, Jie; Ji, Yu-Sheng; Zhao, Bao-Hua; Qu, Yu-Gui; Huang, Xu-Dong; Jiang, Xiu-Fang

2010-01-01

Smart sensors are emerging as a promising technology for a large number of application domains. This paper presents a collection of requirements and guidelines that serve as a basis for a general smart sensor architecture to monitor electricity meters. It also presents an electricity meter monitoring network, named EMMNet, comprised of data collectors, data concentrators, hand-held devices, a centralized server, and clients. EMMNet provides long-distance communication capabilities, which make it suitable suitable for complex urban environments. In addition, the operational cost of EMMNet is low, compared with other existing remote meter monitoring systems based on GPRS. A new dynamic tree protocol based on the application requirements which can significantly improve the reliability of the network is also proposed. We are currently conducting tests on five networks and investigating network problems for further improvements. Evaluation results indicate that EMMNet enhances the efficiency and accuracy in the reading, recording, and calibration of electricity meters.

Uranium enrichment

International Nuclear Information System (INIS)

Rae, H.K.; Melvin, J.G.

1988-06-01

Canada is the world's largest producer and exporter of uranium, most of which is enriched elsewhere for use as fuel in LWRs. The feasibility of a Canadian uranium-enrichment enterprise is therefore a perennial question. Recent developments in uranium-enrichment technology, and their likely impacts on separative work supply and demand, suggest an opportunity window for Canadian entry into this international market. The Canadian opportunity results from three particular impacts of the new technologies: 1) the bulk of the world's uranium-enrichment capacity is in gaseous diffusion plants which, because of their large requirements for electricity (more than 2000 kW·h per SWU), are vulnerable to competition from the new processes; 2) the decline in enrichment costs increases the economic incentive for the use of slightly-enriched uranium (SEU) fuel in CANDU reactors, thus creating a potential Canadian market; and 3) the new processes allow economic operation on a much smaller scale, which drastically reduces the investment required for market entry and is comparable with the potential Canadian SEU requirement. The opportunity is not open-ended. By the end of the century the enrichment supply industry will have adapted to the new processes and long-term customer/supplier relationships will have been established. In order to seize the opportunity, Canada must become a credible supplier during this century

Look at the Beat, Feel the Meter: Top-Down Effects of Meter Induction on Auditory and Visual Modalities.

Science.gov (United States)

Celma-Miralles, Alexandre; de Menezes, Robert F; Toro, Juan M

2016-01-01

Recent research has demonstrated top-down effects on meter induction in the auditory modality. However, little is known about these effects in the visual domain, especially without the involvement of motor acts such as tapping. In the present study, we aim to assess whether the projection of meter on auditory beats is also present in the visual domain. We asked 16 musicians to internally project binary (i.e., a strong-weak pattern) and ternary (i.e., a strong-weak-weak pattern) meter onto separate, but analog, visual and auditory isochronous stimuli. Participants were presented with sequences of tones or blinking circular shapes (i.e., flashes) at 2.4 Hz while their electrophysiological responses were recorded. A frequency analysis of the elicited steady-state evoked potentials allowed us to compare the frequencies of the beat (2.4 Hz), its first harmonic (4.8 Hz), the binary subharmonic (1.2 Hz), and the ternary subharmonic (0.8 Hz) within and across modalities. Taking the amplitude spectra into account, we observed an enhancement of the amplitude at 0.8 Hz in the ternary condition for both modalities, suggesting meter induction across modalities. There was an interaction between modality and voltage at 2.4 and 4.8 Hz. Looking at the power spectra, we also observed significant differences from zero in the auditory, but not in the visual, binary condition at 1.2 Hz. These findings suggest that meter processing is modulated by top-down mechanisms that interact with our perception of rhythmic events and that such modulation can also be found in the visual domain. The reported cross-modal effects of meter may shed light on the origins of our timing mechanisms, partially developed in primates and allowing humans to synchronize across modalities accurately.

Look at the Beat, Feel the Meter: Top–Down Effects of Meter Induction on Auditory and Visual Modalities

Science.gov (United States)

Celma-Miralles, Alexandre; de Menezes, Robert F.; Toro, Juan M.

2016-01-01

Recent research has demonstrated top–down effects on meter induction in the auditory modality. However, little is known about these effects in the visual domain, especially without the involvement of motor acts such as tapping. In the present study, we aim to assess whether the projection of meter on auditory beats is also present in the visual domain. We asked 16 musicians to internally project binary (i.e., a strong-weak pattern) and ternary (i.e., a strong-weak-weak pattern) meter onto separate, but analog, visual and auditory isochronous stimuli. Participants were presented with sequences of tones or blinking circular shapes (i.e., flashes) at 2.4 Hz while their electrophysiological responses were recorded. A frequency analysis of the elicited steady-state evoked potentials allowed us to compare the frequencies of the beat (2.4 Hz), its first harmonic (4.8 Hz), the binary subharmonic (1.2 Hz), and the ternary subharmonic (0.8 Hz) within and across modalities. Taking the amplitude spectra into account, we observed an enhancement of the amplitude at 0.8 Hz in the ternary condition for both modalities, suggesting meter induction across modalities. There was an interaction between modality and voltage at 2.4 and 4.8 Hz. Looking at the power spectra, we also observed significant differences from zero in the auditory, but not in the visual, binary condition at 1.2 Hz. These findings suggest that meter processing is modulated by top–down mechanisms that interact with our perception of rhythmic events and that such modulation can also be found in the visual domain. The reported cross-modal effects of meter may shed light on the origins of our timing mechanisms, partially developed in primates and allowing humans to synchronize across modalities accurately. PMID:27047358

Look at the Beat, Feel the Meter:Top-down Effects of Meter Induction on Auditory and Visual Modalities

Directory of Open Access Journals (Sweden)

Alexandre eCelma-Miralles

2016-03-01

Full Text Available Recent research has demonstrated top-down effects on meter induction in the auditory modality. However, little is known about these effects in the visual domain, especially without the involvement of motor acts such as tapping. In the present study, we aim to assess whether the projection of meter on auditory beats is also present in the visual domain. We asked sixteen musicians to internally project binary (i.e. a strong-weak pattern and ternary (i.e. a strong-weak-weak pattern meter onto separate, but analogue, visual and auditory isochronous stimuli. Participants were presented with sequences of tones or blinking circular shapes (i.e. flashes at 2.4 Hz while their electrophysiological responses were recorded. A frequency analysis of the elicited steady-state evoked potentials allowed us to compare the frequencies of the beat (2.4 Hz, its first harmonic (4.8 Hz, the binary subharmonic (1.2 Hz, and ternary subharmonic (0.8 Hz within and across modalities. Taking the amplitude spectra into account, we observed an enhancement of the amplitude at 0.8 Hz in the ternary condition for both modalities, suggesting meter induction across modalities. There was an interaction between modality and voltage at 2.4 and 4.8 Hz. Looking at the power spectra, we also observed significant differences from zero in the auditory, but not in the visual, binary condition at 1.2 Hz. These findings suggest that meter processing is modulated by top-down mechanisms that interact with our perception of rhythmic events and that such modulation can also be found in the visual domain. The reported cross-modal effects of meter may shed light on the origins of our timing mechanisms, partially developed in primates and allowing humans to synchronize across modalities accurately.

KVP meter errors induced by plastic wrap

International Nuclear Information System (INIS)

Jefferies, D.; Morris, J.W.; White, V.P.

1991-01-01

The purpose of this study was to determine whether erroneous kVp meter readings, induced by plastic wrap, affected the actual kVp (output) of a dental X-ray machine. To evaluate the effect of plastic wrap on dental X-ray machine kVp meters, a radiation output device was used to measure output in mR/ma.s. An intraoral dental X-ray unit (S.S. White Model number-sign 90W) was used to make the exposures. First, the kVp meter was not covered with plastic wrap and output readings were recorded at various kVp settings with the milliamperage and time held constant. Secondly, the same kVp settings were selected before the plastic wrap was placed. Milliamperage and time were again held to the same constant. The X-ray console was then covered with plastic wrap prior to measuring the output for each kVp. The wrap possessed a static charge. This charge induced erroneous kVp meter readings. Out-put readings at the various induced kVp settings were then recorded. A kVp of 50 with no wrap present resulted in the same output as a kVp of 50 induced to read 40 or 60 kVp by the presence of wrap. Similar results were obtained at other kVp settings. This indicates that the plastic wrap influences only the kVp meter needle and not the actual kilovoltage of the X-ray machine. Dental X-ray machine operators should select kVp meter readings prior to placing plastic wrap and should not adjust initial settings if the meter is deflected later by the presence of wrap. The use of such a procedure will result in proper exposures, fewer retakes, and less patient radiation. If plastic wrap leads to consistent exposure errors, clinicians may wish to use a 0.5% sodium hypochlorite disinfectant as an alternative to the barrier technique

Integrating an Embedded System within a Microwave Moisture Meter

Science.gov (United States)

In this paper, the conversion of a PC or laptop-controlled microwave moisture meter to a stand-alone meter hosting its own embedded system is discussed. The moisture meter uses low-power microwaves to measure the attenuation and phase shift of the sample, from which the dielectric properties are cal...

21 CFR 868.1860 - Peak-flow meter for spirometry.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Peak-flow meter for spirometry. 868.1860 Section... (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Diagnostic Devices § 868.1860 Peak-flow meter for spirometry. (a) Identification. A peak-flow meter for spirometry is a device used to measure a patient's...

A novel multiparametric flow cytometry-based cytotoxicity assay simultaneously immunophenotypes effector cells: Comparisons to a 4 h 51Cr-release assay

OpenAIRE

Kim, GG; Donnenberg, VS; Donnenberg, AD; Gooding, W; Whiteside, TL

2007-01-01

Natural killer (NK) cell- or T cell-mediated cytotoxicity traditionally is measured in 4-16h 51Cr-release assays (CRA). A new four-color flow cytometry-based cytotoxicity assay (FCC) was developed to simultaneously measure NK cell cytotoxicity and NK cell phenotype (CD3−CD16+CD56+). Target cells, K562 or Daudi, were labeled with Cell Tracker Orange (CTO) prior to the addition of effector cells. Following co-incubation, 7 amino-actinomycin D (7-AAD) was added to measure death of target cells. ...

Performance of a Modern Glucose Meter in ICU and General Hospital Inpatients: 3 Years of Real-World Paired Meter and Central Laboratory Results.

Science.gov (United States)

Zhang, Ray; Isakow, Warren; Kollef, Marin H; Scott, Mitchell G

2017-09-01

Due to accuracy concerns, the Food and Drug Administration issued guidances to manufacturers that resulted in Center for Medicare and Medicaid Services stating that the use of meters in critically ill patients is "off-label" and constitutes "high complexity" testing. This is causing significant workflow problems in ICUs nationally. We wished to determine whether real-world accuracy of modern glucose meters is worse in ICU patients compared with non-ICU inpatients. We reviewed glucose results over the preceding 3 years, comparing results from paired glucose meter and central laboratory tests performed within 60 minutes of each other in ICU versus non-ICU settings. Seven ICU and 30 non-ICU wards at a 1,300-bed academic hospital in the United States. A total of 14,763 general medicine/surgery inpatients and 20,970 ICU inpatients. None. Compared meter results with near simultaneously performed laboratory results from the same patient by applying the 2016 U.S. Food and Drug Administration accuracy criteria, determining mean absolute relative difference and examining where paired results fell within the Parkes consensus error grid zones. A higher percentage of glucose meter results from ICUs than from non-ICUs passed 2016 Food and Drug Administration accuracy criteria (p meter results with laboratory results. At 1 minute, no meter result from ICUs posed dangerous or significant risk by error grid analysis, whereas at 10 minutes, less than 0.1% of ICU meter results did, which was not statistically different from non-ICU results. Real-world accuracy of modern glucose meters is at least as accurate in the ICU setting as in the non-ICU setting at our institution.

Guanabara Bay and Pecem LNG flexible metering systems

Energy Technology Data Exchange (ETDEWEB)

Torres, Vinicus Roberto C.; Carvalho, Gustavo L.A.; Bruel, Edson L.; Santana, Jose P.C. de; Vidal, Lud C.C.N. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

2009-12-19

This work presents to the community the metering systems installed in the Liquefied Natural (LNG) Gas Flexible Terminals of the Pecem Port and Guanabara Bay. A brief description of the Terminals facilities and its operation is firstly made to provide a background of the systems discussed. Then, the LNG custody transfer metering system, the operational control metering system, the energy balance of the LNG transferring system and the Natural Gas custody transfer metering system - that are our systems of interest - are described in detail. It is intended to use the philosophy adopted in the Guanabara Bay and Pecem Flexible Terminals design as a standard to future installations, integrated with improvements brought by the operation experience that will be obtained in those terminals. (author)

Feasibility of Low Enriched Uranium Fuel for Space Nuclear Propulsion

Energy Technology Data Exchange (ETDEWEB)

Venneri, Paolo; Kim, Yonghee [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

2013-05-15

The purpose of this initial study is to create a baseline with which to perform further analysis and to build a solid understanding of the neutronic characteristics of a solid core for the nuclear thermal rocket. Once consistency with work done at Idaho National Laboratory (INL) is established, this paper will provide a study of other fuel types, such as low and medium-enriched uranium fuels. This paper will examine how the implementation of each fuel type affects the multiplication factor of the reactor, and will then explore different possibilities for alterations needed to accommodate their successful usage. The reactor core analysis was done using the MCNP5 code. While this study has not shown that the SNRE can be easily retrofitted for low-enriched U fuel, it has made a detailed study of the SNRE, and identified the difficulties of the implementation of low-enriched fuels in small nuclear rockets. These difficulties are the need for additional moderation and fuel mass in order to achieve a critical mass. Neither of these is insurmountable. Future work includes finding the best method by which to increase the internal moderation of the reactor balanced with appropriate sizing to prevent neutron leakage. Both of these are currently being studied. This paper will present a study of the Small Nuclear Rocket Engine (SNRE) and the feasibility of using low enriched Uranium (LEU) instead of the traditional high enriched Uranium (HEU) fuels.

The disc pasture meter: Possible applications in grazing management.

African Journals Online (AJOL)

The disc meter is a simple inexpensive instrument which may be used to make rapid yield estimates of standing forage. Linear regression relationships between meter reading and pasture dry matter yield are usually fairly good, but these may be affected by a number of different factors. The meter should therefore be ...

Hydrogen meter for service in liquid sodium

International Nuclear Information System (INIS)

McCown, J.J.

1983-11-01

This standard establishes the requirements for the design, materials, fabrication, quality assurance, examination, and acceptance testing of a hydrogen meter and auxiliary equipment for use in radioactive or nonradioactive liquid sodium service. The meter shall provide a continuous and accurate indication of the hydrogen impurity concentration over the range 0.03 to 10 ppM hydrogen in sodium at temperatures between 800 and 1000 0 F (427 and 538 0 C). The meter may also be used to rapidly monitor changes in hydrogen concentration, over the same concentration range, and, therefore can be used as a sensor for sodium-water reactions in LMFBR steam generators

Additional functions of remotely read kWh-meters

Energy Technology Data Exchange (ETDEWEB)

Koponen, P. [VTT Energy, Espoo (Finland); Vehvilaeinen, S. [Mittrix Oy (Finland); Rantanen, J. [Helsinki Energy Board, Helsinki (Finland)

1996-12-31

In this presentation the possibilities to include new applications into remotely read smart kWh-meters are considered. New electronic meters can measure various electric quantities and have some extra calculating capacity. So they can be used to provide functions that distribution automation and the customer need and thus share the costs. Some applications like monitoring the state of the distribution network or locating faults are only for the utility, but many applications also need an interface to the customer or his automation system. Among those are monitoring the quality of electricity, estimating load curves, applying dynamic tariffs and selling electricity and accounting. As a special item, the continuous monitoring of the quality of electricity is discussed. This includes voltage levels, total distortion, asymmetry and so on. If such a kWh-meter indicates quality problems the situation can be detected with a suitable portable quality meter. The poor quality can be detected before it causes harm to equipment owned by the customers or the power distribution company. This presentation also presents a prototype of such a quality monitoring kWh-meter

Additional functions of remotely read kWh-meters

Energy Technology Data Exchange (ETDEWEB)

Koponen, P [VTT Energy, Espoo (Finland); Vehvilaeinen, S [Mittrix Oy (Finland); Rantanen, J [Helsinki Energy Board, Helsinki (Finland)

1997-12-31

In this presentation the possibilities to include new applications into remotely read smart kWh-meters are considered. New electronic meters can measure various electric quantities and have some extra calculating capacity. So they can be used to provide functions that distribution automation and the customer need and thus share the costs. Some applications like monitoring the state of the distribution network or locating faults are only for the utility, but many applications also need an interface to the customer or his automation system. Among those are monitoring the quality of electricity, estimating load curves, applying dynamic tariffs and selling electricity and accounting. As a special item, the continuous monitoring of the quality of electricity is discussed. This includes voltage levels, total distortion, asymmetry and so on. If such a kWh-meter indicates quality problems the situation can be detected with a suitable portable quality meter. The poor quality can be detected before it causes harm to equipment owned by the customers or the power distribution company. This presentation also presents a prototype of such a quality monitoring kWh-meter

Development of in vitro and in vivo rabies virus neutralization assays based on a high-titer pseudovirus system

Science.gov (United States)

Nie, Jianhui; Wu, Xiaohong; Ma, Jian; Cao, Shouchun; Huang, Weijin; Liu, Qiang; Li, Xuguang; Li, Yuhua; Wang, Youchun

2017-01-01

Pseudoviruses are useful virological tools because of their safety and versatility; however the low titer of these viruses substantially limits their wider applications. We developed a highly efficient pseudovirus production system capable of yielding 100 times more rabies pseudovirus than the traditional method. Employing the high-titer pseudoviruses, we have developed robust in vitro and in vivo neutralization assays for the evaluation of rabies vaccine, which traditionally relies on live-virus based assays. Compared with current rapid fluorescent focus inhibition test (RFFIT), our in vitro pseudovirus-based neutralization assay (PBNA) is much less labor-intensive while demonstrating better reproducibility. Moreover, the in vivo PBNA assay was also found to be superior to the live virus based assay. Following intravenous administration, the pseudovirus effectively infected the mice, with dynamic viral distributions being sequentially observed in spleen, liver and brain. Furthermore, data from in vivo PBNA showed great agreement with those generated from the live virus model but with the experimental time significantly reduced from 2 weeks to 3 days. Taken together, the effective pseudovirus production system facilitated the development of novel PBNA assays which could replace live virus-based traditional assays due to its safety, rapidity, reproducibility and high throughput capacity. PMID:28218278

Advanced enrichment techniques

International Nuclear Information System (INIS)

Johnson, A.

1988-01-01

BNFL is in a unique position in that it has commercial experience of diffusion enrichment, and of centrifuge enrichment through its associate company Urenco. In addition BNFL is developing laser enrichment techniques as part of a UK development programme in this area. The paper describes the development programme which led to the introduction of competitive centrifuge enrichment technology by Urenco and discusses the areas where improvements have and will continue to be made in the centrifuge process. It also describes the laser development programme currently being undertaken in the UK. The paper concludes by discussing the relative merits of the various methods of uranium enrichment, with particular reference to the enrichment market likely to obtain over the rest of the century

Advanced enrichment techniques

International Nuclear Information System (INIS)

Johnson, A.

1987-01-01

BNFL is in a unique position in that it has commercial experience of diffusion enrichment, and of centrifuge enrichment through its associate company Urenco. In addition BNFL is developing laser enrichment techniques as part of a UK development programme in this area. The paper describes the development programme which led to the introduction of competitive centrifuge enrichment technology by Urenco and discusses the areas where improvements have and will continue to be made in the centrifuge process. It also describes the laser development programme currently being undertaken in the UK. The paper concludes by discussing the relative merits of the various methods of uranium enrichment, with particular reference to the enrichment market likely to obtain over the rest of the century. (author)

Polarization speed meter for gravitational-wave detection

Science.gov (United States)

Wade, Andrew R.; McKenzie, Kirk; Chen, Yanbei; Shaddock, Daniel A.; Chow, Jong H.; McClelland, David E.

2012-09-01

We propose a modified configuration of an advanced gravitational-wave detector that is a speed-meter-type interferometer with improved sensitivity with respect to quantum noise. With the addition of polarization-controlling components to the output of an arm cavity Michelson interferometer, an orthogonal polarization state of the interferometer can be used to store signal, returning it later with opposite phase to cancel position information below the storage bandwidth of the opposite mode. This modification provides an alternative to an external kilometer-scale Fabry-Pérot cavity, as presented in earlier work of Purdue and Chen [Phys. Rev. D 66, 122004 (2002)]. The new configuration requires significantly less physical infrastructure to achieve speed meter operation. The quantity of length and alignment degrees of freedom is also reduced. We present theoretical calculations to show that such a speed meter detector is capable of beating the strain sensitivity imposed by the standard quantum limit over a broad range of frequencies for Advanced Laser Interferometer Gravitational-wave Observatory-like parameters. The benefits and possible difficulties of implementing such a scheme are outlined. We also present results for tuning of the speed meter by adjusting the degree of polarization coupling, a novel possibility that does not exist in previously proposed designs, showing that there is a smooth transition from speed meter operation to that of a signal-recycling Michelson behavior.

Hybrid Enrichment Verification Array: Module Characterization Studies

Energy Technology Data Exchange (ETDEWEB)

Zalavadia, Mital A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Smith, Leon E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McDonald, Benjamin S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kulisek, Jonathan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mace, Emily K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deshmukh, Nikhil S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2016-03-01

The work presented in this report is focused on the characterization and refinement of the Hybrid Enrichment Verification Array (HEVA) approach, which combines the traditional 186-keV ²³⁵U signature with high-energy prompt gamma rays from neutron capture in the detector and surrounding collimator material, to determine the relative enrichment and ²³⁵U mass of the cylinder. The design of the HEVA modules (hardware and software) deployed in the current field trial builds on over seven years of study and evolution by PNNL, and consists of a ø3''×3'' NaI(Tl) scintillator coupled to an Osprey digital multi-channel analyzer tube base from Canberra. The core of the HEVA methodology, the high-energy prompt gamma-ray signature, serves as an indirect method for the measurement of total neutron emission from the cylinder. A method for measuring the intrinsic efficiency of this “non-traditional” neutron signature and the results from a benchmark experiment are presented. Also discussed are potential perturbing effects on the non-traditional signature, including short-lived activation of materials in the HEVA module. Modeling and empirical results are presented to demonstrate that such effects are expected to be negligible for the envisioned implementation scenario. In comparison to previous versions, the new design boosts the high-energy prompt gamma-ray signature, provides more flexible and effective collimation, and improves count-rate management via commercially available pulse-processing electronics with a special modification prompted by PNNL.

Juvenile psittacine environmental enrichment.

Science.gov (United States)

Simone-Freilicher, Elisabeth; Rupley, Agnes E

2015-05-01

Environmental enrichment is of great import to the emotional, intellectual, and physical development of the juvenile psittacine and their success in the human home environment. Five major types of enrichment include social, occupational, physical, sensory, and nutritional. Occupational enrichment includes exercise and psychological enrichment. Physical enrichment includes the cage and accessories and the external home environment. Sensory enrichment may be visual, auditory, tactile, olfactory, or taste oriented. Nutritional enrichment includes variations in appearance, type, and frequency of diet, and treats, novelty, and foraging. Two phases of the preadult period deserve special enrichment considerations: the development of autonomy and puberty. Copyright © 2015 Elsevier Inc. All rights reserved.

Optimization on Measurement Method for Neutron Moisture Meter

International Nuclear Information System (INIS)

Gong Yalin; Wu Zhiqiang; Li Yanfeng; Wang Wei; Song Qingfeng; Liu Hui; Wei Xiaoyun; Zhao Zhonghua

2010-01-01

When the water in the measured material is nonuniformity, the measured results of the neutron moisture meter in the field may have errors, so the measured errors of the moisture meter associated with the water nonuniformity in material were simulated by Monte Carlo method. A new measurement method of moisture meter named 'transmission plus scatter' was put forward. The experiment results show that the new measurement method can reduce the error even if the water in the material is nonuniformity. (authors)

Uranium enrichment

International Nuclear Information System (INIS)

1989-01-01

GAO was asked to address several questions concerning a number of proposed uranium enrichment bills introduced during the 100th Congress. The bill would have restructured the Department of Energy's uranium enrichment program as a government corporation to allow it to compete more effectively in the domestic and international markets. Some of GAO's findings discussed are: uranium market experts believe and existing market models show that the proposed DOE purchase of a $750 million of uranium from domestic producers may not significantly increase production because of large producer-held inventories; excess uranium enrichment production capacity exists throughout the world; therefore, foreign producers are expected to compete heavily in the United States throughout the 1990s as utilities' contracts with DOE expire; and according to a 1988 agreement between DOE's Offices of Nuclear Energy and Defense Programs, enrichment decommissioning costs, estimated to total $3.6 billion for planning purposes, will be shared by the commercial enrichment program and the government

Isotope enrichment

International Nuclear Information System (INIS)

Lydtin, H-J.; Wilden, R.J.; Severin, P.J.W.

1978-01-01

The isotope enrichment method described is based on the recognition that, owing to mass diffusion and thermal diffusion in the conversion of substances at a heated substrate while depositing an element or compound onto the substrate, enrichment of the element, or a compound of the element, with a lighter isotope will occur. The cycle is repeated for as many times as is necessary to obtain the degree of enrichment required

Field Trial of LANL On-Line Advanced Enrichment Monitor for UF6 GCEP

Energy Technology Data Exchange (ETDEWEB)

Ianakiev, Kiril D. [Los Alamos National Laboratory; Lombardi, Marcie [Los Alamos National Laboratory; MacArthur, Duncan W. [Los Alamos National Laboratory; Parker, Robert F. [Los Alamos National Laboratory; Smith, Morag K. [Los Alamos National Laboratory; Keller, Clifford [Los Alamos National Laboratory; Friend, Peter [URENCO; Dunford, Andrew [URENCO

2012-07-13

The outline of this presentation is: (1) Technology basis of on-line enrichment monitoring; (2) Timescale of trial; (3) Description of installed equipment; (4) Photographs; (5) Results; (6) Possible further development; and (7) Conclusions. Summary of the good things about the Advanced Enrichment Monitor (AEM) performance is: (1) High accuracy - normally better than 1% relative, (2) Active system as accurate as passive system, (3) Fast and accurate detection of enrichment changes, (4) Physics is well understood, (5) Elegant method for capturing pressure signal, and (6) Data capture is automatic, low cost and fast. A couple of negative things are: (1) Some jumps in measured passive enrichment - of around +2% relative (due to clock errors?); and (2) Data handling and evaluation is off-line, expensive and very slow. Conclusions are: (1) LANL AEM is being tested on E23 plant at Capenhurst; (2) The trial is going very well; (3) AEM could detect production of HEU at potentially much lower cost than existing CEMO; (4) AEM can measure {sup 235}U assay accurately; (5) Active system using X-Ray source would avoid need for pressure measurement; (6) Substantial work lies ahead to go from current prototype to a production instrument.

Radiofrequency fields associated with the Itron smart meter.

Science.gov (United States)

Tell, R A; Sias, G G; Vazquez, A; Sahl, J; Turman, J P; Kavet, R I; Mezei, G

2012-08-01

This study examined radiofrequency (RF) emissions from smart electric power meters deployed in two service territories in California for the purpose of evaluating potential human exposure. These meters included transmitters operating in a local area mesh network (RF LAN, ∼250 mW); a cell relay, which uses a wireless wide area network (WWAN, ∼1 W); and a transmitter serving a home area network (HAN, ∼70 mW). In all instances, RF fields were found to comply by a wide margin with the RF exposure limits established by the US Federal Communications Commission. The study included specialised measurement techniques and reported the spatial distribution of the fields near the meters and their duty cycles (typically smart meters as deployed. However, the results are restricted to a single manufacturer's emitters.

Solutions For Smart Metering Under Harsh Environmental Condicions

Directory of Open Access Journals (Sweden)

Kunicina N.

2015-02-01

Full Text Available The described case study concerns application of wireless sensor networks to the smart control of power supply substations. The solution proposed for metering is based on the modular principle and has been tested in the intersystem communication paradigm using selectable interface modules (IEEE 802.3, ISM radio interface, GSM/GPRS. The solution modularity gives 7 % savings of maintenance costs. The developed solution can be applied to the control of different critical infrastructure networks using adapted modules. The proposed smart metering is suitable for outdoor installation, indoor industrial installations, operation under electromagnetic pollution, temperature and humidity impact. The results of tests have shown a good electromagnetic compatibility of the prototype meter with other electronic devices. The metering procedure is exemplified by operation of a testing company's workers under harsh environmental conditions.

Pulse counting period meter output during startup transients

International Nuclear Information System (INIS)

Cummins, J.D.

1962-12-01

The time response of a period meter whose input signal comes from a pulse counting channel may be calculated using a Ferranti Mercury autocode programme details of which are given. The period meter considered is the type for which the logarithmic characteristic is approximated by several diode pump circuits. The input excitation is a terminated ramp of reactivity. Other reactivity inputs may be treated. In particular the step change of reactivity may be used as the input excitation. Allowance is made for the effective time constants of the diode pump circuits and the period meter. The programme may be used for instrument assessment and for safety and operations studies on reactors which use this type of period meter. An example of the use of the programme is given. (author)

IMAGE TYPE WATER METER CHARACTER RECOGNITION BASED ON EMBEDDED DSP

OpenAIRE

LIU Ying; HAN Yan-bin; ZHANG Yu-lin

2015-01-01

In the paper, we combined DSP processor with image processing algorithm and studied the method of water meter character recognition. We collected water meter image through camera at a fixed angle, and the projection method is used to recognize those digital images. The experiment results show that the method can recognize the meter characters accurately and artificial meter reading is replaced by automatic digital recognition, which improves working efficiency.

Optimisation of the RT-PCR detection of immunomagnetically enriched carcinoma cells

International Nuclear Information System (INIS)

Raynor, Michael; Stephenson, Sally-Anne; Walsh, David CA; Pittman, Kenneth B; Dobrovic, Alexander

2002-01-01

Immunomagnetic enrichment followed by RT-PCR (immunobead RT-PCR) is an efficient methodology to identify disseminated carcinoma cells in the blood and bone marrow. The RT-PCR assays must be both specific for the tumor cells and sufficiently sensitive to enable detection of single tumor cells. We have developed a method to test RT-PCR assays for any cancer. This has been investigated using a panel of RT-PCR markers suitable for the detection of breast cancer cells. In the assay, a single cell line-derived tumor cell is added to 100 peripheral blood mononuclear cells (PBMNCs) after which mRNA is isolated and reverse transcribed for RT-PCR analysis. PBMNCs without added tumor cells are used as specificity controls. The previously studied markers epidermal growth factor receptor (EGFR), mammaglobin 1 (MGB1), epithelial cell adhesion molecule (EpCAM/TACSTD1), mucin 1 (MUC1), carcinoembryonic antigen (CEA) were tested. Two new epithelial-specific markers ELF3 and EphB4 were also tested. MUC1 was unsuitable as strong amplification was detected in 100 cell PBMNC controls. Expression of ELF3, EphB4, EpCAM, EGFR, CEA and MGB1 was found to be both specific for the tumor cell, as demonstrated by the absence of a signal in most 100 cell PBMNC controls, and sensitive enough to detect a single tumor cell in 100 PBMNCs using a single round of RT-PCR. ELF3, EphB4, EpCAM, EGFR, CEA and MGB1 are appropriate RT-PCR markers for use in a marker panel to detect disseminated breast cancer cells after immunomagnetic enrichment

Metagenome enrichment approach used for selection of oil-degrading bacteria consortia for drill cutting residue bioremediation.

Science.gov (United States)

Guerra, Alaine B; Oliveira, Jorge S; Silva-Portela, Rita C B; Araújo, Wydemberg; Carlos, Aline C; Vasconcelos, Ana Tereza R; Freitas, Ana Teresa; Domingos, Yldeney Silva; de Farias, Mirna Ferreira; Fernandes, Glauber José Turolla; Agnez-Lima, Lucymara F

2018-04-01

Drill cuttings leave behind thousands of tons of residues without adequate treatment, generating a large environmental liability. Therefore knowledge about the microbial community of drilling residue may be useful for developing bioremediation strategies. In this work, samples of drilling residue were enriched in different culture media in the presence of petroleum, aiming to select potentially oil-degrading bacteria and biosurfactant producers. Total DNA was extracted directly from the drill cutting samples and from two enriched consortia and sequenced using the Ion Torrent platform. Taxonomic analysis revealed the predominance of Proteobacteria in the metagenome from the drill cuttings, while Firmicutes was enriched in consortia samples. Functional analysis using the Biosurfactants and Biodegradation Database (BioSurfDB) revealed a similar pattern among the three samples regarding hydrocarbon degradation and biosurfactants production pathways. However, some statistical differences were observed between samples. Namely, the pathways related to the degradation of fatty acids, chloroalkanes, and chloroalkanes were enriched in consortia samples. The degradation colorimetric assay using dichlorophenolindophenol as an indicator was positive for several hydrocarbon substrates. The consortia were also able to produce biosurfactants, with biosynthesis of iturin, lichnysin, and surfactin among the more abundant pathways. A microcosms assay followed by gas chromatography analysis showed the efficacy of the consortia in degrading alkanes, as we observed a reduction of around 66% and 30% for each consortium in total alkanes. These data suggest the potential use of these consortia in the bioremediation of drilling residue based on autochthonous bioaugmentation. Copyright © 2018 Elsevier Ltd. All rights reserved.

Technique of Hurdle Clearing in 400 Meters Hurdles

OpenAIRE

Jakoubek, Jiří

2018-01-01

Title: Technique of Hurdle Clearing in 400 Meters Hurdles Authors: Jiří Jakoubek Supervisor: PhDr. Aleš Kaplan, Ph.D. Aims: The aim of this thesis is to describe technique of hurdle clearing in 400 meters hurdle race using study review and to examine this technique at particular athlete during training and racing sessions in 400 meters hurdles race. Methods: Technique was compared and examined at young athlete. Two kinograms were used for analysis, one from training and one from racing sessio...

Characteristics of starch breads enriched with red potatoes

Directory of Open Access Journals (Sweden)

Dorota Gumul

2017-01-01

Full Text Available Starch breads may often be low in nutritional value, in comparison to traditional products, as they contain less dietary fibre, protein and micro and macro elements. As an effect a risk of mineral deficiencies and digestive problems caused by lack of dietary fibre could be expected in persons adhering to gluten free diet. To eliminate such problems, a continuous research on gluten-free bread nutritional enrichment, has been done in recent years. Raw material used to enrich gluten free products should include: inulin, lupine, radish, soy, lucerne sprouts, oilseeds, different type of dried fruits. Among the most commonly used raw materials, there are flours from gluten free cereals and pseudocereals such as buckwheat, amaranth and maize are very popular. It seem that valuable alternative could be considered a red, purple or pink potatoes as starch breads additives. The aim of this work was to investigate the effect addition of freeze-dried color potatoes on crude fiber, polyphenols, anthocyanins and flavonoids and nutritional value of gluten free breads. It could be concluded, that freeze-dried color (red, purple, pink potatoes enriched the gluten free breads (starch breads with health promoting bioactive components, like polyphenols, and highly valuable protein. The most promising additive was Magenta Love red potato variety lyophilisates, because gluten free breads enriched with this component were characterized by high protein content and the highest content of free and bound polyphenols, flavonoids, anthocyanins. The presence of all these components increased the nutritional and pro-health value of gluten free product as starch bread.

Predicting wind shear effects: A study of Minnesota wind data collected at heights up to 70 meters

Energy Technology Data Exchange (ETDEWEB)

Artig, R. [Minnesota Dept. of Public Service, St. Paul, MN (United States)

1997-12-31

The Minnesota Department of Public Service (DPS) collects wind data at carefully selected sites around the state and analyzes the data to determine Minnesota`s wind power potential. DPS recently installed advanced new monitoring equipment at these sites and began to collect wind data at 30, 50, and 70 meters above ground level, with two anemometers at each level. Previously, the Department had not collected data at heights above ground level higher than 30 meters. DPS also, with the U.S. Department of Energy (DOE), installed four sophisticated monitoring sites as part of a Tall Tower Wind Shear Study that is assessing the effects of wind shear on wind power potential. At these sites, wind data are being collected at the 10, 30, 40, 50, 60, and 70 meter heights. This paper presents the preliminary results of the analysis of wind data from all sites. These preliminary results indicate that the traditional 1/7 power law does not effectively predict wind shear in Minnesota, and the result is an underestimation of Minnesota`s wind power potential at higher heights. Using a power factor of 1/5 or 1/4 may be more accurate and provide sound justification for installing wind turbines on taller towers in Minnesota.

IMPORTANT: Fluke is recalling Digital Clamp Meters

CERN Multimedia

2013-01-01

Fluke is voluntarily recalling four models of Digital Clamp Meters: Fluke 373, 374, 375 and 376. If you own one of these clamp meters, please stop using it and send it back to Fluke for repair even if you have not experienced problems.   Description of the problem: "The printed circuit assembly may not be properly fastened to the test lead input jack. This may result in inaccurate voltage readings, including a low or no-voltage reading on a circuit energised with a hazardous voltage, presenting a shock, electrocution or thermal burn hazard." To determine if your clamp meter is affected by this recall notice, and for more information, click here.

Ramp Metering Influence on Freeway Operational Safety near On-ramp Exits

Directory of Open Access Journals (Sweden)

Chiu Liu, PhD, PE, PTOE

2013-06-01

Full Text Available Ramp metering has been widely installed in urban areas where congestion on a freeway or an expressway may occur recurrently during weekday peak periods to enhance mainline throughput and reduce system-wide delay. These operational benefits may also help reduce vehicular emissions and improve air quality in urban areas. However, the impact on traffic safety due to ramp metering hasn't been explored in details before. Supported by physical understanding and arguments, we characterize the ramp metering influence on freeway safety by examining vehicular collisions near on-ramp exits within the ramp meter operating hours before and after the activation of the ramp metering. Collisions for a sample of 19 operating ramp meters along several freeways in northern California were collected and organized to show that ramp metering can help reduce freeway collisions at the vicinity of on-ramp exits. It was found that the average reductions on freeway collisions in the vicinity of an on-ramp exit are around 36%. Although most of the reduced collisions belong to the property damage only category, a 36% reduction shows the significant safety benefit of ramp metering. The traffic congestion induced by each collision, especially during peak hours when ramp metering is in operation, could last for an hour or two. Consequently, ramp metering must be contributing to the reduction of non-recurrent congestion in addition to mitigating recurrent congestion, which is better documented. This study strongly supports the implementation of ramp metering in California.

Polyphenols and antioxidant activities of Kombucha beverage enriched with Coffeeberry® extract

Directory of Open Access Journals (Sweden)

Essawet Najmi Ahmed

2015-01-01

Full Text Available Kombucha is a traditional beverage obtained by fermenting sweetened black tea with tea fungus, which represents a consortium of acetic acid bacteria and yeasts. Also, CoffeeBerry® products, which derived from the whole fruit of the coffee plant, are valuable ingredients with nutritional and health-enhancing potential. Samples of fermentation broths enriched with CoffeeBerry® extract and traditional Kombucha were analysed. The fermentation was performed in a bioreactor at 28±1°C for nine days. The results showed that the CoffeeBerry® extract has contributed to a faster fermentation of cultivation medium. Some individual polyphenolic compounds and catehins in fermentation broth samples were identified and quantified by High Performance Liquid Chromatography (HPLC. Among the bioactive compounds present in investigated samples obtained during Kombucha fermentation of the sweetened black tea enriched with CoffeeBerry® extract, chlorogenic acid (188.94-458.56 μg/mL was the predominant. The antioxidant activity of investigated samples was tested by measuring their ability to scavenge DPPH and reactive hydroxyl radicals by electron spin resonance (ESR spectroscopy. The scavenging activities on DPPH and hydroxyl radicals were increased with duration of fermentation. IC50 values for Kombucha fermentation broth enriched with CoffeBerry®, based on DPPH and hydroxyl radical scavenging activities, were in the range 26.33-170.13 μL/mL and 11.33-102.22 μL/mL, respectively.

Field-Metered Data from Portable Unit Dehumidifiers in the U.S. Residential Sector: Initial Results of a Pilot Study

Energy Technology Data Exchange (ETDEWEB)

Willem, Henry [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Beraki, Bereket [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Burke, Tom [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Melody, Moya [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Nagaraju, Mythri [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Ni, Chun Chun [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Pratt, Stacy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Dominique Yang, Hung-Chia [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division

2013-01-29

The work described herein is intended to enrich the body of literature regarding dehumidifiers in residential settings—in particular the hours of use and energy consumption of various types of dehumidifiers. In the United States, portable unit dehumidifiers most commonly are used in basements during humid summer days in northern climates. Dehumidifier energy consumption differs among households depending on settings selected by the user, frequency of use, and conditions of operation. Although some estimates of dehumidifier use have been developed, and a few metering studies performed, there remains a paucity of metered data collected from individual households that use dehumidifiers. For this study we obtained field data on the energy consumption of dehumidifiers to supplement currently available analyses. Our goal was to obtain data from a pilot study that we could use to develop initial distributions describing the capacities and applications of dehumidifiers used in individual homes. More precisely characterizing the use of dehumidifiers in real-world applications will enable a more accurate estimate of the range of energy use in various operational modes. Our pilot field-metering exercise was aimed at compiling real-time data on the energy consumption of portable dehumidifiers in residential households in the New England and Mid-Atlantic areas. Our analysis furthers the process of developing a more precise estimate of dehumidifier energy use, which will support the evaluation of the potential energy savings and attendant costs associated with more energy efficient dehumidifiers.

Autonomous replication of plasmids bearing monkey DNA origin-enriched sequences

International Nuclear Information System (INIS)

Frappier, L.; Zannis-Hadjopoulos, M.

1987-01-01

Twelve clones of origin-enriched sequences (ORS) isolated from early replicating monkey (CV-1) DNA were examined for transient episomal replication in transfected CV-1, COS-7, and HeLa cells. Plasmid DNA was isolated at time intervals after transfection and screened by the Dpn I resistance assay or by the bromodeoxyuridine substitution assay to differentiate between input and replicated DNA. The authors have identified four monkey ORS (ORS3, -8, -9, and -12) that can support plasmid replication in mammalian cells. This replication is carried out in a controlled and semiconservative manner characteristic of mammalian replicons. ORS replication was most efficient in HeLa cells. Electron microscopy showed ORS8 and ORS12 plasmids of the correct size with replication bubbles. Using a unique restriction site in ORS12, we have mapped the replication bubble within the monkey DNA sequence

Some problems in calibrating surface contamination meters

International Nuclear Information System (INIS)

Chen Zigen; LI Xingyuan; Shuai Xiaoping.

1984-01-01

It is necessary that instruments are calibrated accurately in order to obtain reliable survey data of surface contamination. Some problems in calibrating surface contamination meters are expounded in this paper. Measurement comparison for beta surface contamination meters is organized within limited scope, thus survey quality is understood, questions are discovered, significance of calibration is expounded further. (Author)

BCM6: New Generation of Boron Meter

International Nuclear Information System (INIS)

Pirat, P.

2010-01-01

Full text of publication follows: Rolls-Royce has developed a new generation of boron meter, based on more than 30 years of experience. The Rolls-Royce BCM6 boron meter provides Nuclear Power Plant (NPP) operators with the boron concentration of the primary circuit. The meter provides continuous and safe measurements with no manual sampling and no human contact. In this paper, technical features, advantages and customer benefits of the use of the new generation of Rolls-Royce BCM6 boron meter will be detailed. Values and associated alarms are provides over different media: 4-20 mA outputs, relays, displays in the main control room and in the chemical lab, and digital links. A special alarm avoids unexpected homogeneous dilution of the primary circuit, which is a critical operational parameter. The Rolls-Royce BCM6 boron meter is fully configurable over a set of parameters allowing adaptation to customer needs. It has a differential capability, thus eliminating neutronic noise and keeping measurements accurate, even in the case of fuel clad rupture. Measurements are accurate, reliable, and have a quick response time. Equipment meets state-of-the-art qualification requests. Designed in 2008, the BCM6 boron meter is the newest equipment of Rolls-Royce boron meters product line. It has been chosen to equip the French EPR NPP and complies with the state-of-the-art of the technology. Rolls-Royce has more than 30 years of experience in Instrumentation and Controls with more than 75 NPP units operating worldwide. All of this experience return has been put in this new generation of equipment to provide the customer with the best operation. About Rolls-Royce Rolls-Royce is a global business providing integrated power systems for use on land, at sea and in the air. The Group has a balanced business portfolio with leading market positions. Rolls-Royce has a broad range of civil nuclear expertise, including work related to licensing and safety reviews, engineering design

Carbon activity meter

International Nuclear Information System (INIS)

Roy, P.; Krankota, J.L.

1975-01-01

A carbon activity meter utilizing an electrochemical carbon cell with gaseous reference electrodes having particular application for measuring carbon activity in liquid sodium for the LMFBR project is described. The electrolyte container is electroplated with a thin gold film on the inside surface thereof, and a reference electrode consisting of CO/CO 2 gas is used. (U.S.)

Interest in smart metering project surprises utility, IBM

International Nuclear Information System (INIS)

Horne, D.

2006-01-01

This article provided an outline of Hydro Ottawa and IBM's smart metering pilot project, which has resulted in high approval ratings from the public. The project features 375 participants broken down into 3 separate groups to look for potential consumption differences between customers charged according to standard time-of-use pricing; time-of-use with critical peak pricing; and time-of-use with critical peak rebates. The Ontario Smart Price Pilot project will be run for 5 months, and is expected to provide detailed energy information about usage. Past projects have indicated that customers respond quickly to smart metering, as they are able to monitor their energy usage and more effectively manage their energy consumption. Ontario plans to have all homes and small businesses using smart meters by 2010, as high seasonal demand has indicated that conservation and balanced resource use are now top priorities for many utility companies. At least 10 states in the United States have conducted smart metering pilot projects. The California Public Utilities Commissions has recently approved a $1.7 billion statewide plan to replace old meters with smart meters. In Ontario, customers have ordered 10,000 electricity monitors that Hydro One is giving away. It was concluded that research results from an earlier Hydro One demonstration project with 500 Ontario homeowners showed that real time electricity monitors can help homeowners reduce their consumption of electricity by up to 15 per cent. 4 figs

Microprocessor controlled digital period meter

International Nuclear Information System (INIS)

Keefe, D.J.; McDowell, W.P.; Rusch, G.K.

1980-01-01

A microprocessor controlled digital period meter has been developed and tested operationally on a reactor at Argonne National Laboratory. The principle of operation is the mathematical relationship between asymptotic periods and pulse counting circuitry. This relationship is used to calculate and display the reactor periods over a range of /plus or minus/1 second to /plus or minus/999 seconds. The time interval required to update each measurement automatically varies from 8 seconds at the lowest counting rates to 2 seconds at higher counting rates. The paper will describe hardware and software design details and show the advantages of this type of Period Meter over the conventional circuits. 1 ref

Two-channel neutron boron meter

International Nuclear Information System (INIS)

Chen Yongqing; Yin Guowei; Chai Songshan; Deng Zhaoping; Zhou Bin

1993-09-01

The two-channel neutron boron meter is a continuous on-line measuring device to measure boron concentration of primary cooling liquid of reactors. The neutron-leakage-compensation method is taken in the measuring mechanism. In the primary measuring configuration, the mini-boron-water annulus and two-channel and central calibration loop are adopted. The calibration ring and constant-temperature of boron-water can be remotely controlled by secondary instruments. With the microcomputer data processing system the boron concentration is automatically measured and calibrated in on-line mode. The meter has many advantages such as high accuracy, fast response, multi-applications, high reliability and convenience

Epithelial cells as alternative human biomatrices for comet assay.

Science.gov (United States)

Rojas, Emilio; Lorenzo, Yolanda; Haug, Kristiane; Nicolaissen, Bjørn; Valverde, Mahara

2014-01-01

The comet assay is a valuable experimental tool aimed at mapping DNA damage in human cells in vivo for environmental and occupational monitoring, as well as for therapeutic purposes, such as storage prior to transplant, during tissue engineering, and in experimental ex vivo assays. Furthermore, due to its great versatility, the comet assay allows to explore the use of alternative cell types to assess DNA damage, such as epithelial cells. Epithelial cells, as specialized components of many organs, have the potential to serve as biomatrices that can be used to evaluate genotoxicity and may also serve as early effect biomarkers. Furthermore, 80% of solid cancers are of epithelial origin, which points to the importance of studying DNA damage in these tissues. Indeed, studies including comet assay in epithelial cells have either clear clinical applications (lens and corneal epithelial cells) or examine genotoxicity within human biomonitoring and in vitro studies. We here review improvements in determining DNA damage using the comet assay by employing lens, corneal, tear duct, buccal, and nasal epithelial cells. For some of these tissues invasive sampling procedures are needed. Desquamated epithelial cells must be obtained and dissociated prior to examination using the comet assay, and such procedures may induce varying amounts of DNA damage. Buccal epithelial cells require lysis enriched with proteinase K to obtain free nucleosomes. Over a 30 year period, the comet assay in epithelial cells has been little employed, however its use indicates that it could be an extraordinary tool not only for risk assessment, but also for diagnosis, prognosis of treatments and diseases.

Antioxidant Capacity of a Turkish Traditional Alcoholic Drink, Raki

Directory of Open Access Journals (Sweden)

Yalcin Gorkem

2016-07-01

Full Text Available Raki is an aniseed flavoured traditional Turkish alcoholic drink. Antioxidant capacity of raki samples from different commercial brands were evaluated by CUPRAC, DPPH, TEAC and ORAC assays and correlations between these assays and total phenolic content were also investigated. Additionally, the one-way ANOVA and Bonferroni tests were performed to compare differences between values of the samples. Results indicated that different raki samples exhibited different antioxidant capacity and total phenolic content. The mean antioxidant capacity values of samples were in the order of: ORAC>TEAC>CUPRAC>DPPH. The correlations of total phenolic content of samples with their CUPRAC, TEAC and ORAC results were found statistically significant, while DPPH assay showed no significant correlation.

Duplex real-time PCR assay using SYBR Green to detect and quantify Malayan box turtle (Cuora amboinensis) materials in meatballs, burgers, frankfurters and traditional Chinese herbal jelly powder.

Science.gov (United States)

Asing; Ali, Eaqub; Hamid, Sharifah Bee Abd; Hossain, Motalib; Ahamad, Mohammad Nasir Uddin; Hossain, S M Azad; Naquiah, Nina; Zaidul, I S M

2016-11-01

The Malayan box turtle (Cuora amboinensis) (MBT) is a vulnerable and protected species widely used in exotic foods and traditional medicines. Currently available polymerase chain reaction (PCR) assays to identify MBT lack automation and involve long targets which break down in processed or denatured tissue. This SYBR Green duplex real-time PCR assay has addressed this research gap for the first time through the combination of 120- and 141-bp targets from MBT and eukaryotes for the quantitative detection of MBT DNA in food chain and herbal medicinal preparations. This authentication ensures better security through automation, internal control and short targets that were stable under the processing treatments of foods and medicines. A melting curve clearly demonstrated two peaks at 74.63 ± 0.22 and 78.40 ± 0.31°C for the MBT and eukaryotic products, respectively, under pure, admixed and commercial food matrices. Analysis of 125 reference samples reflected a target recovery of 93.25-153.00%, PCR efficiency of 99-100% and limit of detection of 0.001% under various matrices. The quantification limits were 0.00001, 0.00170 ± 0.00012, 0.00228 ± 0.00029, 0.00198 ± 0.00036 and 0.00191 ± 0.00043 ng DNA for the pure meat, binary mixtures, meatball, burger and frankfurter products, respectively. The assay was used to screen 100 commercial samples of traditional Chinese herbal jelly powder from eight different brands; 22% of them were found to be MBT-positive (5.37 ± 0.50-7.00 ± 0.34% w/w), which was reflected through the Ct values (26.37 ± 0.32-28.90 ± 0.42) and melting curves (74.63-78.65 ± 0.22°C) of the amplified MBT target (120 bp), confirming the speculation that MBT materials are widely used in Chinese herbal desserts, exotic dishes consumed with the hope of prolonging life and youth.

Development of PIC-based digital survey meter

International Nuclear Information System (INIS)

Nor Arymaswati Abdullah; Nur Aira Abdul Rahman; Mohd Ashhar Khalid; Taiman Kadni; Glam Hadzir Patai Mohamad; Abd Aziz Mhd Ramli; Chong Foh Yong

2006-01-01

The need of radiation monitoring and monitoring of radioactive contamination in the workplace is very important especially when x-ray machines, linear accelerators, electron beam machines and radioactive sources are present. The appropriate use of radiation detector is significant in order to maintain a radiation and contamination free workplace. This paper reports on the development of a prototype of PIC-based digital survey meter. This prototype of digital survey meter is a hand held instrument for general-purpose radiation monitoring and surface contamination meter. Generally, the device is able to detect some or all of the three major types of ionizing radiation, namely alpha, beta and gamma. It uses a Geiger-Muller tube as a radiation detector, which converts gamma radiation quanta to electric pulses and further processed by the electronic devices. The development involved the design of the controller, counter and high voltage circuit. All these circuit are assembled and enclosed in a plastic casing together with a GM detector and LCD display to form a prototype survey meter. The number of counts of the pulses detected by the survey meter varies due to the random nature of radioactivity. By averaging the reading over a time-period, more accurate and stable reading is achieved. To test the accuracy and the linearity of the design, the prototype was calibrated using standard procedure at the Secondary Standard Dosimetry Laboratory (SSDL) in MINT. (Author)

Status of neutron monitoring meters for radiation protection purpose

International Nuclear Information System (INIS)

Li Taosheng

2003-01-01

The status of and trends towards the development of neutron monitoring meters, such as dose survey meter, workplace (ambient) spectrometer and individual dosimeters, are discussed in the present paper from the perspectives of workplace and individual dose monitoring. Over the past 4 decades, both neutron dose survey meter and workplace spectrometer have declined to be more reasonable in design of their probes, with more broaden applications. With the development of electronic technology, there is a trend towards being more small-compacted and smart. Although many technical difficulties in the practical measurement, some significant progresses have be made in the development and research of these kinds of meters. (authors)

Downhole multiphase metering in wells by means of soft-sensing

NARCIS (Netherlands)

Leskens, M.; Kruif, B. de; Belfroid, S.P.C.; Smeulers, J.P.M.; Gryzlov, A.

2008-01-01

Multiphase flow meters are indispensable tools for achieving optimal operation and control of wells as these meters deliver real-time information about their performance. For example, multiphase flow meters located downhole can improve the production of multilateral and multizone wells by timely

Hybrid TLC-pair meter for the Sphinx Project

Science.gov (United States)

Wada, T.; Yamamoto, I.; Takahashi, N.; Misaki, A.

1985-01-01

The chief aims in THE SPHINX PROJECT are research of super lepton physics and new detector experiments. At the second phase of THE SPHINX PROJECT, a hybrid TLC-PAIR METER was designed for measuring high energy neutrino sources (E upsilon * TeV), searching high energy muon sources (E mu TeV) and measuring muon group (E mu 1 TeV). The principle of PAIR METER has been already proposed. In this TLC-PAIR METER, electromagnetic shower induced by cosmic ray muons are detected using TL (Thermoluminescence) sheets with position counters.

Hybrid TLC-pair meter for the Sphinx Project

International Nuclear Information System (INIS)

Wada, T.; Yamamoto, I.; Takahashi, N.; Misaki, A.

1985-01-01

The chief aims in the Sphinx Project are research on super lepton physics and new detector experiments. In the second phase of the Sphinx Project, a hybrid TLC-pair meter was designed for measuring for high energy neutrino sources (E upsilon * TeV), searching high energy muon sources (E mu TeV), and measuring muon groups (E mu 1 TeV). The principle of the pair meter has been already proposed. In this TLC pair meter, electromagnetic showers induced by cosmic ray muons are detected using thermoluminescene sheets with position counters

Federal metering data analysis needs and existing tools

Energy Technology Data Exchange (ETDEWEB)

Henderson, Jordan W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fowler, Kimberly M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2015-07-01

Agencies have been working to improve their metering data collection, management, and analysis efforts over the last decade (since EPAct 2005) and will continue to address these challenges as new requirements and data needs come into place. Unfortunately there is no “one-size-fits-all” solution. As agencies continue to expand their capabilities to use metered consumption data to reducing resource use and improve operations, the hope is that shared knowledge will empower others to follow suit. This paper discusses the Federal metering data analysis needs and some existing tools.

Deducing Energy Consumer Behavior from Smart Meter Data

DEFF Research Database (Denmark)

Ebeid, Emad Samuel Malki; Heick, Rune; Jacobsen, Rune Hylsberg

2017-01-01

The ongoing upgrade of electricity meters to smart ones has opened a new market of intelligent services to analyze the recorded meter data. This paper introduces an open architecture and a unified framework for deducing user behavior from its smart main electricity meter data and presenting...... the results in a natural language. The framework allows a fast exploration and integration of a variety of machine learning algorithms combined with data recovery mechanisms for improving the recognition’s accuracy. Consequently, the framework generates natural language reports of the user’s behavior from...

Real time Aanderaa current meter data collection system

Digital Repository Service at National Institute of Oceanography (India)

AshokKumar, K.; Diwan, S.G.

Aanderaa current meters are widely used for recording the current speed and such other 4 parameters by deploying them over extended period of time. Normally data are recorded on magnetic tape and after recovery of current meters, data are read...

Analysis of an indirect neutron signature for enhanced UF{sub 6} cylinder verification

Energy Technology Data Exchange (ETDEWEB)

Kulisek, J.A., E-mail: Jonathan.Kulisek@pnnl.gov; McDonald, B.S.; Smith, L.E.; Zalavadia, M.A.; Webster, J.B.

2017-02-21

The International Atomic Energy Agency (IAEA) currently uses handheld gamma-ray spectrometers combined with ultrasonic wall-thickness gauges to verify the declared enrichment of uranium hexafluoride (UF{sub 6}) cylinders. The current method provides relatively low accuracy for the assay of {sup 235}U enrichment, especially for natural and depleted UF{sub 6}. Furthermore, the current method provides no capability to assay the absolute mass of {sup 235}U in the cylinder due to the localized instrument geometry and limited penetration of the 186-keV gamma-ray signature from {sup 235}U. Also, the current verification process is a time-consuming component of on-site inspections at uranium enrichment plants. Toward the goal of a more-capable cylinder assay method, the Pacific Northwest National Laboratory has developed the hybrid enrichment verification array (HEVA). HEVA measures both the traditional 186-keV direct signature and a non-traditional, high-energy neutron-induced signature (HEVA{sub NT}). HEVA{sub NT} enables full-volume assay of UF{sub 6} cylinders by exploiting the relatively larger mean free paths of the neutrons emitted from the UF{sub 6}. In this work, Monte Carlo modeling is used as the basis for characterizing HEVA{sub NT} in terms of the individual contributions to HEVA{sub NT} from nuclides and hardware components. Monte Carlo modeling is also used to quantify the intrinsic efficiency of HEVA for neutron detection in a cylinder-assay geometry. Modeling predictions are validated against neutron-induced gamma-ray spectra from laboratory measurements and a relatively large population of Type 30B cylinders spanning a range of enrichments. Implications of the analysis and findings on the viability of HEVA for cylinder verification are discussed, such as the resistance of the HEVA{sub NT} signature to manipulation by the nearby placement of neutron-conversion materials.

Analysis of an indirect neutron signature for enhanced UF_6 cylinder verification

International Nuclear Information System (INIS)

Kulisek, J.A.; McDonald, B.S.; Smith, L.E.; Zalavadia, M.A.; Webster, J.B.

2017-01-01

The International Atomic Energy Agency (IAEA) currently uses handheld gamma-ray spectrometers combined with ultrasonic wall-thickness gauges to verify the declared enrichment of uranium hexafluoride (UF_6) cylinders. The current method provides relatively low accuracy for the assay of "2"3"5U enrichment, especially for natural and depleted UF_6. Furthermore, the current method provides no capability to assay the absolute mass of "2"3"5U in the cylinder due to the localized instrument geometry and limited penetration of the 186-keV gamma-ray signature from "2"3"5U. Also, the current verification process is a time-consuming component of on-site inspections at uranium enrichment plants. Toward the goal of a more-capable cylinder assay method, the Pacific Northwest National Laboratory has developed the hybrid enrichment verification array (HEVA). HEVA measures both the traditional 186-keV direct signature and a non-traditional, high-energy neutron-induced signature (HEVA_N_T). HEVA_N_T enables full-volume assay of UF_6 cylinders by exploiting the relatively larger mean free paths of the neutrons emitted from the UF_6. In this work, Monte Carlo modeling is used as the basis for characterizing HEVA_N_T in terms of the individual contributions to HEVA_N_T from nuclides and hardware components. Monte Carlo modeling is also used to quantify the intrinsic efficiency of HEVA for neutron detection in a cylinder-assay geometry. Modeling predictions are validated against neutron-induced gamma-ray spectra from laboratory measurements and a relatively large population of Type 30B cylinders spanning a range of enrichments. Implications of the analysis and findings on the viability of HEVA for cylinder verification are discussed, such as the resistance of the HEVA_N_T signature to manipulation by the nearby placement of neutron-conversion materials.

ORNL Pocket Meter Program: internal operating procedures

International Nuclear Information System (INIS)

Berger, C.D.; Miller, J.H.; Dunsmore, M.R.

1984-12-01

The ORNL Pocket Meter Program is designed for auditing the approximate photon radiation exposure of Oak Ridge National Laboratory (ORNL) radiation workers. Although pocket meters are considered to be a secondary personnel dosimetry system at ORNL, they are valuable indicators of unplanned exposures if proper procedures are followed for testing, calibrating, deploying, wearing, processing, and recording data. 4 figures, 1 table

Implementation plan for smart meters in Ontario

International Nuclear Information System (INIS)

2004-01-01

This paper presents Ontario Energy Board's implementation plan to install 800,000 smart meters by December 31, 2007. The objective is to help consumers control their electricity bills through conservation and demand response. The three conditions that will change power consumption habits are price changes in response to demand and supply forces; the ability of consumers to see and respond to the price signals; and, a measurement of the response so that consumers get credit for their actions. This paper identifies the mandatory technical requirements for smart meters and the support operations of distributors. It sets priorities, identifies barriers and regulatory mechanisms for cost recovery. It also discusses options for ownership of the meters. 18 refs., 1 tab., 2 figs

Additional functions of remotely read kWh-meters

Energy Technology Data Exchange (ETDEWEB)

Koponen, P [VTT Energy, Espoo (Finland); Vehvilaeinen, S [Mittrix Oy (Finland); Rantanen, J [Helsinki Energy Board (Finland)

1998-08-01

In this chapter the possibilities to include new applications into remotely read smart kWh-meters are considered. New electronic meters can measure various electric quantities and have some extra calculating capacity. So they can be used to provide functions that distribution automation and the customer need and thus share the costs. Some applications like monitoring the state of the distribution network or locating faults are only for the utility, but many applications also need an interface to the customers or their automation systems. Among those are monitoring the quality of electricity, estimating load curves, applying dynamic tariffs and selling electricity and accounting. As a special item, the continuous monitoring of the quality of electricity is discussed. This includes voltage levels, total distortion, asymmetry and so on. If such a kWh-meter indicates quality problems it is possible to go there with a portable quality meter that is suitable for the case and inspect the situation. The poor quality can be detected before it causes harm to equipment owned by the customers or the power distribution company. This article also presents a prototype of such a quality monitoring kWh-meter. Dynamic tariffs and free electricity markets require two way communication with the utility and the customer and measurement of the time variations of the energy consumption. The customers or their energy management system must receive the energy prices from the utility and calculate the energy costs and decide upon the energy consumption control actions. Some alternative ways to meet these customer interface requirements are compared. Remote reading of kWh-meters requires a certain investment in meters and their data communication with the utility. Because smart meters can have some additional memory and calculating capacity and are capable of measuring various electric quantities, it is possible to share the costs with other applications that use the same hardware and data

Optical position meters analyzed in the noninertial reference frames

International Nuclear Information System (INIS)

Tarabrin, Sergey P.; Seleznyov, Alexander A.

2008-01-01

In the framework of general relativity we develop a method for the analysis of the operation of the optical position meters in their photodetectors proper reference frames. These frames are noninertial in general due to the action of external fluctuative forces on meters test masses, including detectors. For comparison we also perform the calculations in the laboratory (globally inertial) reference frame and demonstrate that for certain optical schemes laboratory-based analysis results in unmeasurable quantities, in contrast to the detector-based analysis. We also calculate the response of the simplest optical meters to weak plane gravitational waves and fluctuative motions of their test masses. It is demonstrated that for the round-trip meter analysis in both the transverse-traceless (TT) and local Lorentz (LL) gauges produces equal results, while for the forward-trip meter corresponding results differ in accordance with different physical assumptions (e.g. procedure of clocks synchronization) implicitly underlying the construction of the TT and LL gauges.

Uranium enrichment plans

International Nuclear Information System (INIS)

Thomas, D.C.; Gagne, R.W.

1978-01-01

The following topics are covered: the status of the Government's existing uranium enrichment services contracts, natural uranium requirements based on the latest contract information, uncertainty in predicting natural uranium requirements based on uranium enrichment contracts, and domestic and foreign demand assumed in enrichment planning

Smart metering gateway works as Smart Home Energy Manager; Smart Metering Gateway als Smart Home Energy Manager

Energy Technology Data Exchange (ETDEWEB)

Walter, Klaus-Dieter [SSV Software Systems GmbH, Hannover (Germany)

2011-07-01

The installation of smart meters together with real time consumption data visualization doesn't help to save energy CO2 emissions. With regards to refinancing options, the situation in Germany has been quite different since the middle of last year for buildings equipped with a photovoltaic system. If a heat pump system is also present, intelligent energy use in conjunction with smart meters can save considerable amounts of money. A Smart Home Energy Manager (SHEM) automates the energy saving. (orig.)

Electric Power Substitute Meter Management via Mobile Application

Directory of Open Access Journals (Sweden)

Nelson C. Rodelas

2014-10-01

Full Text Available EPSMvMA is composed of Digital Sub-Meter connected to different components namely the GSM module, Bluetooth module, Power Analyzer Module, LCD Module, Relay Module and Main Microcontroller module. The connection via Mobile is made possible by the modules mentioned. The software that the proponents will be dealing with in the study is C++ language, which will be used in programming the Main Microcontroller module and Visual Basic Language for the Android Phones. The Bluetooth module can access the Android Phones and connect to the digital sub-meter in a limited distance. The users will be at ease since a code embedded to the microcontroller will make the utility sub-meter produce the desired value of electricity (KWH and wherein the computed Sub-meter reading can be viewed through the LCD. This project is accommodating to those person that is always on the go and prudent.

Radiofrequency fields associated with the Itron smart meter

International Nuclear Information System (INIS)

Tell, R. A.; Sias, G. G.; Vazquez, A.; Sahl, J.; Turman, J. P.; Kavet, R. I.; Mezei, G.

2008-01-01

This study examined radiofrequency (RF) emissions from smart electric power meters deployed in two service territories in California for the purpose of evaluating potential human exposure. These meters included transmitters operating in a local area mesh network (RF LAN, ∼250 mW); a cell relay, which uses a wireless wide area network (WWAN, ∼1 W); and a transmitter serving a home area network (HAN, ∼70 mW). In all instances, RF fields were found to comply by a wide margin with the RF exposure limits established by the US Federal Communications Commission. The study included specialised measurement techniques and reported the spatial distribution of the fields near the meters and their duty cycles (typically <1 %) whose value is crucial to assessing time-averaged exposure levels. This study is the first to characterise smart meters as deployed. However, the results are restricted to a single manufacturer's emitters. (authors)

Reactor Power Meter type SG-8

Energy Technology Data Exchange (ETDEWEB)

Glowacki, S W

1981-01-01

The report describes the principle and electronic circuits of the Reactor Power Meter type SG-8. The gamma radiation caused by the activity of the reactor first cooling circuit affectes the ionization chamber being the detector of the instrument. The output detector signal direct current is converted into the frequency of electric pulses by means of the current-to-frequency converter. The output converter frequency is measured by the digital frequency meter: the number of measured digits in time unit is proportional to the reactor power.

Liquid metal Flow Meter - Final Report

Energy Technology Data Exchange (ETDEWEB)

Andersen, C.; Hoogendoom, S.; Hudson, B.; Prince, J.; Teichert, K.; Wood, J.; Chase, K.

2007-01-30

Measuring the flow of liquid metal presents serious challenges. Current commercially-available flow meters use ultrasonic, electromagnetic, and other technologies to measure flow, but are inadequate for liquid metal flow measurement because of the high temperatures required by most liquid metals. As a result of the reactivity and high temperatures of most liquid metals, corrosion and leakage become very serious safety concerns. The purpose of this project is to develop a flow meter for Lockheed Martin that measures the flow rate of molten metal in a conduit.

Chlorophyll meter for estimating nitrogen status of irrigated wheat

International Nuclear Information System (INIS)

Schepers, J.S.

2000-01-01

Chlorophyll-meter readings, generated from the leaves of irrigated wheat at particular growth stages, were normalized to the data obtained with locally recommended rates of fertilizer N, in Chile China, India and Mexico. Normalizing permitted comparisons of crop-N status across growth stages, locations, cultivars, and years. Relative yields and meter readings at growth-stage Z-50 are presented; they revealed similar trends for India, China, and Chile, however, for Mexico, the combination of soil, wheat cultivar, and climate resulted in much less response to N fertilization in the meter data. The implications are discussed. The SPAD meter proved to be a good tool to monitor and evaluate the N status of irrigated wheat. (author)

Nondestructive assay of sale materials

International Nuclear Information System (INIS)

Rodenburg, W.W.; Fleissner, J.G.

1981-01-01

This paper covers three primary areas: (1) reasons for performing nondestructive assay on SALE materials; (2) techniques used; and (3) discussion of investigators' revised results. The study shows that nondestructive calorimetric assay of plutonium offers a viable alternative to traditional wet chemical techniques. For these samples, the precision ranged from 0.4 to 0.6% with biases less than 0.2%. Thus, for those materials where sampling errors are the predominant source of uncertainty, this technique can provide improved accuracy and precision while saving time and money as well as reducing the amount of liquid wastes to be handled. In addition, high resolution gamma-ray spectroscopy measurements of solids can provide isotopic analysis data in a cost effective and timely manner. The timeliness of the method can be especially useful to the plant operator for production control and quality control measurements

Delineating a road-salt plume in lakebed sediments using electrical resistivity, piezometers, and seepage meters at Mirror Lake, New Hampshire, U.S.A

Science.gov (United States)

Toran, Laura; Johnson, Melanie; Nyquist, Jonathan E.; Rosenberry, Donald O.

2010-01-01

Electrical-resistivity surveys, seepage meter measurements, and drive-point piezometers have been used to characterize chloride-enriched groundwater in lakebed sediments of Mirror Lake, New Hampshire, U.S.A. A combination of bottom-cable and floating-cable electrical-resistivity surveys identified a conductive zone (ohm-m)">(ohm-m)(ohm-m) overlying resistive bedrock (ohm-m)">(ohm-m)(ohm-m)beneath the lake. Shallow pore-water samples from piezometers in lakebed sediments have chloride concentrations of 200–1800μeq/liter">200–1800μeq/liter200–1800μeq/liter, and lake water has a chloride concentration of 104μeq/liter">104μeq/liter104μeq/liter. The extent of the plume was estimated and mapped using resistivity and water-sample data. The plume (20×35m">20×35m20×35m wide and at least 3m">3m3m thick) extends nearly the full length and width of a small inlet, overlying the top of a basin formed by the bedrock. It would not have been possible to mapthe plume's shape without the resistivity surveys because wells provided only limited coverage. Seepage meters were installed approximately 40m">40m40m from the mouth of a small stream discharging at the head of the inlet in an area where the resistivity data indicated lake sediments are thin. These meters recorded in-seepage of chloride-enriched groundwater at rates similar to those observed closer to shore, which was unexpected because seepage usually declines away from shore. Although the concentration of road salt in the northeast inlet stream is declining, the plume map and seepage data indicate the groundwater contribution of road salt to the lake is not declining. The findings demonstrate the benefit of combining geophysical and hydrologic data to characterize discharge of a plume beneath Mirror Lake. The extent of the plume in groundwater beneath the lake and stream indicate there will likely be a long-term source of chloride to the lake from groundwater.

How Should Blood Glucose Meter System Analytical Performance Be Assessed?

Science.gov (United States)

Simmons, David A

2015-08-31

Blood glucose meter system analytical performance is assessed by comparing pairs of meter system and reference instrument blood glucose measurements measured over time and across a broad array of glucose values. Consequently, no single, complete, and ideal parameter can fully describe the difference between meter system and reference results. Instead, a number of assessment tools, both graphical (eg, regression plots, modified Bland-Altman plots, and error grid analysis) and tabular (eg, International Organization for Standardization guidelines, mean absolute difference, and mean absolute relative difference) have been developed to evaluate meter system performance. The strengths and weaknesses of these methods of presenting meter system performance data, including a new method known as Radar Plots, are described here. © 2015 Diabetes Technology Society.

Enrichment and Molecular Analysis of Breast Cancer Disseminated Tumor Cells from Bone Marrow Using Microfiltration.

Directory of Open Access Journals (Sweden)

Sreeraj G Pillai

Full Text Available Molecular characterization of disseminated tumor cells (DTCs in the bone marrow (BM of breast cancer (BC patients has been hindered by their rarity. To enrich for these cells using an antigen-independent methodology, we have evaluated a size-based microfiltration device in combination with several downstream biomarker assays.BM aspirates were collected from healthy volunteers or BC patients. Healthy BM was mixed with a specified number of BC cells to calculate recovery and fold enrichment by microfiltration. Specimens were pre-filtered using a 70 μm mesh sieve and the effluent filtered through CellSieve microfilters. Captured cells were analyzed by immunocytochemistry (ICC, FISH for HER-2/neu gene amplification status, and RNA in situ hybridization (RISH. Cells eluted from the filter were used for RNA isolation and subsequent qRT-PCR analysis for DTC biomarker gene expression.Filtering an average of 14×106 nucleated BM cells yielded approximately 17-21×103 residual BM cells. In the BC cell spiking experiments, an average of 87% (range 84-92% of tumor cells were recovered with approximately 170- to 400-fold enrichment. Captured BC cells from patients co-stained for cytokeratin and EpCAM, but not CD45 by ICC. RNA yields from 4 ml of patient BM after filtration averaged 135ng per 10 million BM cells filtered with an average RNA Integrity Number (RIN of 5.3. DTC-associated gene expression was detected by both qRT-PCR and RISH in filtered spiked or BC patient specimens but, not in control filtered normal BM.We have tested a microfiltration technique for enrichment of BM DTCs. DTC capture efficiency was shown to range from 84.3% to 92.1% with up to 400-fold enrichment using model BC cell lines. In patients, recovered DTCs can be identified and distinguished from normal BM cells using multiple antibody-, DNA-, and RNA-based biomarker assays.

Other enrichment related contracts

International Nuclear Information System (INIS)

Hall, J.C.

1978-01-01

In addition to long-term enrichment contracts, DOE has other types of contracts: (1) short-term, fixed-commitment enrichment contract; (2) emergency sales agreement for enriched uranium; (3) feed material lease agreement; (4) enriched uranium storage agreement; and (5) feed material usage agreement

Topology-Based Estimation of Missing Smart Meter Readings

Directory of Open Access Journals (Sweden)

Daisuke Kodaira

2018-01-01

Full Text Available Smart meters often fail to measure or transmit the data they record when measuring energy consumption, known as meter readings, owing to faulty measuring equipment or unreliable communication modules. Existing studies do not address successive and non-periodical missing meter readings. This paper proposes a method whereby missing readings observed at a node are estimated by using circuit theory principles that leverage the voltage and current data from adjacent nodes. A case study is used to demonstrate the ability of the proposed method to successfully estimate the missing readings over an entire day during which outages and unpredictable perturbations occurred.

Evaluation of the antioxidants activities of four Slovene medicinal plant species by traditional and novel biosensory assays.

Science.gov (United States)

Kintzios, Spiridon; Papageorgiou, Katerina; Yiakoumettis, Iakovos; Baricevic, Dea; Kusar, Anita

2010-11-02

We investigated the antioxidant activity of methanolic and water extracts of Slovene accessions of four medicinal plant species (Salvia officinalis, Achillea millefolium, Origanum vulgare subsp. vulgare and Gentiana lutea). Their free radical-scavenging activity against the DPPH. free radical was studied with a spectrophotometric assay, while their biological activity with the help of a laboratory-made biosensor based on immobilized fibroblast cells (assay duration: 3 min). The observed antioxidant activity of the extracts from the four investigated medicinal plant species was dependent on both the solvent used for extraction and the assay method (conventional or biosensor-based). Independently from the assay method and the solvent used for extraction, the lowest scavenging activity was observed in root extracts of G. lutea. Treatment of the immobilized cells with the plant extracts resulted in an increase of the cell membrane potential (membrane hyperpolarization), possibly due to the reduction of membrane damage due to oxidation. The novel cell biosensor could be utilized as a rapid, high throughput tool for screening the antioxidant properties of plant-derived compounds. Copyright (c) 2010 Elsevier B.V. All rights reserved.

A committee report on the state-of-art of uranium isotope enrichment measurement techniques

International Nuclear Information System (INIS)

1982-06-01

The activity of a sectional meeting (June, 1979 - February, 1982) for uranium enrichment measurement under the Committee on Analytical Chemistry of Nuclear Fuels and Reactor Materials is summarized. In the first part of this report, the object and present state of the measurement at the following organization are described; two development organizations (Power Reactor and Nuclear Fuel Development Corporation and Japan Nuclear Fuel Development), two nuclear fuel makers (Japan Nuclear Fuel and Mitsubishi Nuclear Fuel), one safeguards inspection organization (Nuclear Material Control Center) and one research organization (Japan Atomic Energy Research Institute). The second part contains the principle and technique of several measurement methods for uranium isotopic assay, such as mass spectrometry, passive and active assays and optical spectral method. Lastly, the concept of the reference materials and its practical information for mass spectrometry and non-destructive assay are described. (author)

Arrival-Time Detection and Ultrasonic Flow-Meter Applications

International Nuclear Information System (INIS)

Willatzen, Morten; Soendergaard, Peter; Latino, Carl; Voss, Frands; Andersen, Niels Lervad; Brokate, Martin; Bounaim, Aicha

2006-01-01

The Danfoss problem on ultrasonic flow measurement has been separated into three parts each handled by a subgroup of the authors listed above. The first subgroup deals with a presentation of modelling equations describing the physics of ultrasonic flow meters employing reciprocal ultrasonic transducer systems. The mathematical model presented allows the electrical output signal to be determined corresponding to any time-dependent electrical input signal. The transducers modelled consist of a piezoceramic material layer and a passive acoustic matching layer. The second subgroup analyzes the possibility of coding the input signal so as to simplify arrival-time detection by re.nding the coded input sequence in the received signal. The narrow-band nature of the transducers makes this problem non-trivial but suggestions for improvement are proposed. The analysis given is based on traditional autoand cross-correlation techniques. The third subgroup attempts to improve existing correlation methods in determining arrival-time detection of signals. A mathematical formulation of the problem is given and the application to a set of real signals provided by Danfoss A/S is performed with good results

Integration of auditory and tactile inputs in musical meter perception.

Science.gov (United States)

Huang, Juan; Gamble, Darik; Sarnlertsophon, Kristine; Wang, Xiaoqin; Hsiao, Steven

2013-01-01

Musicians often say that they not only hear but also "feel" music. To explore the contribution of tactile information to "feeling" music, we investigated the degree that auditory and tactile inputs are integrated in humans performing a musical meter-recognition task. Subjects discriminated between two types of sequences, "duple" (march-like rhythms) and "triple" (waltz-like rhythms), presented in three conditions: (1) unimodal inputs (auditory or tactile alone); (2) various combinations of bimodal inputs, where sequences were distributed between the auditory and tactile channels such that a single channel did not produce coherent meter percepts; and (3) bimodal inputs where the two channels contained congruent or incongruent meter cues. We first show that meter is perceived similarly well (70-85 %) when tactile or auditory cues are presented alone. We next show in the bimodal experiments that auditory and tactile cues are integrated to produce coherent meter percepts. Performance is high (70-90 %) when all of the metrically important notes are assigned to one channel and is reduced to 60 % when half of these notes are assigned to one channel. When the important notes are presented simultaneously to both channels, congruent cues enhance meter recognition (90 %). Performance dropped dramatically when subjects were presented with incongruent auditory cues (10 %), as opposed to incongruent tactile cues (60 %), demonstrating that auditory input dominates meter perception. These observations support the notion that meter perception is a cross-modal percept with tactile inputs underlying the perception of "feeling" music.

Development of in vitro assay method with radioisotope

International Nuclear Information System (INIS)

Choi, Chang Woon; Lim, S. M.; An, S. H.; Woo, K. S.; Chung, W. S.; Lim, S. J.; Hong, S. W.; Oh, O. D.

1999-04-01

Radioimmunoassay (RIA) and related competitive protein-binding methods began a little over 20 years ago as a cumbersome research methodology in a few specialized laboratories. Endocrinology has been greatly enriched by the new knowledge that has come as a direct result of RIA methods. Establishment of the taxol RIA system will be expected to develop RIA for drug monitoring. Scintillation proximity assay was useful since any separation step is not required, it has the advantage of dealing with multiple samples. The increased sensitivity of the new assay in determining HCV RT([ 125 I]dUTP) suggests that it would be worth investigating whether the system can be applied to analysis. [ 125 I] lodotyramine with 98.5% radiochemical purity. Optimal background counts was certificated using varied radioactivity of radionuclides. Appropriate standard curve was obtained from SPA method successively, and the concentration of hCG from unknown serum was determined by standard curve. The result concentration of hCG from unknown serum was determined by synthesized successively and purified by HPLC system. Hybridoma reducing monoclonal anti thyroglobulin antibodies titer is measured by ELISA. These studies play an important role in development of in vitro assay with radionuclides

Development of in vitro assay method with radioisotope

Energy Technology Data Exchange (ETDEWEB)

Choi, Chang Woon; Lim, S. M.; An, S. H.; Woo, K. S.; Chung, W. S.; Lim, S. J.; Hong, S. W. [Korea Atomic Energy Research Institute. Korea Cancer Center Hospital, Seoul (Korea, Republic of); Oh, O. D. [Yonsei University, Seoul (Korea, Republic of)

1999-04-01

Radioimmunoassay (RIA) and related competitive protein-binding methods began a little over 20 years ago as a cumbersome research methodology in a few specialized laboratories. Endocrinology has been greatly enriched by the new knowledge that has come as a direct result of RIA methods. Establishment of the taxol RIA system will be expected to develop RIA for drug monitoring. Scintillation proximity assay was useful since any separation step is not required, it has the advantage of dealing with multiple samples. The increased sensitivity of the new assay in determining HCV RT([{sup 125}I]dUTP) suggests that it would be worth investigating whether the system can be applied to analysis. [{sup 125}I] lodotyramine with 98.5% radiochemical purity. Optimal background counts was certificated using varied radioactivity of radionuclides. Appropriate standard curve was obtained from SPA method successively, and the concentration of hCG from unknown serum was determined by standard curve. The result concentration of hCG from unknown serum was determined by synthesized successively and purified by HPLC system. Hybridoma reducing monoclonal anti thyroglobulin antibodies titer is measured by ELISA. These studies play an important role in development of in vitro assay with radionuclides.

Development of quick-response area-averaged void fraction meter

International Nuclear Information System (INIS)

Watanabe, Hironori; Iguchi, Tadashi; Kimura, Mamoru; Anoda, Yoshinari

2000-11-01

Authors are performing experiments to investigate BWR thermal-hydraulic instability under coupling of neutronics and thermal-hydraulics. To perform the experiment, it is necessary to measure instantaneously area-averaged void fraction in rod bundle under high temperature/high pressure gas-liquid two-phase flow condition. Since there were no void fraction meters suitable for these requirements, we newly developed a practical void fraction meter. The principle of the meter is based on the electrical conductance changing with void fraction in gas-liquid two-phase flow. In this meter, metal flow channel wall is used as one electrode and a L-shaped line electrode installed at the center of flow channel is used as the other electrode. This electrode arrangement makes possible instantaneous measurement of area-averaged void fraction even under the metal flow channel. We performed experiments with air/water two-phase flow to clarify the void fraction meter performance. Experimental results indicated that void fraction was approximated by α=1-I/I o , where α and I are void fraction and current (I o is current at α=0). This relation holds in the wide range of void fraction of 0∼70%. The difference between α and 1-I/I o was approximately 10% at maximum. The major reasons of the difference are a void distribution over measurement area and an electrical insulation of the center electrode by bubbles. The principle and structure of this void fraction meter are very basic and simple. Therefore, the meter can be applied to various fields on gas-liquid two-phase flow studies. (author)

Research on data collection key technology of smart electric energy meters

Science.gov (United States)

Chen, Xiangqun; Huang, Rui; Shen, Liman; Chen, Hao; Xiong, Dezhi; Xiao, Xiangqi; Mouhailiu; Renheng, Xu

2018-02-01

In recent years, smart electric energy meters are demand at 70 million to 90 million with the strong smart grid construction every year in China. However, there are some issues in smart electric energy meters data collection such as the interference of environment, low collection efficiency and inability to work when the power is off. In order to solve these issues above, it uses the RFID communication technology to collect the numbers and electric energy information of smart electric energy meters on the basis of the existing smart electric energy meters, and the related data collection communication experiments were made. The experimental result shows that the electric information and other data batch collection of RFID smart electric energy meters are realized in power and power off. It improves the efficiency and the overall success rate is 99.2% within 2 meters. It provides a new method for smart electric energy meters data collection.

A wireless mesh communication protocol for smart-metering

NARCIS (Netherlands)

Geelen, D.J.M.; Kempen, van G.M.P.; Hoogstraten, van F.; Liotta, A.

2012-01-01

Worldwide there has been increasing interest over the past few years for so-called "Smart Meters", in academia, governments and in industry. Such smart-metering systems need a way to communicate the collected data reliably and cost efficiently to the back-office for analysis. Several competing

7 CFR 801.6 - Tolerances for moisture meters.

Science.gov (United States)

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Tolerances for moisture meters. 801.6 Section 801.6 Agriculture Regulations of the Department of Agriculture (Continued) GRAIN INSPECTION, PACKERS AND STOCKYARD... FOR GRAIN INSPECTION EQUIPMENT § 801.6 Tolerances for moisture meters. (a) The maintenance tolerances...

Rapid multiplex detection of 10 foodborne pathogens with an up-converting phosphor technology-based 10-channel lateral flow assay

Science.gov (United States)

Zhao, Yong; Wang, Haoran; Zhang, Pingping; Sun, Chongyun; Wang, Xiaochen; Wang, Xinrui; Yang, Ruifu; Wang, Chengbin; Zhou, Lei

2016-01-01

The rapid high-throughput detection of foodborne pathogens is essential in controlling food safety. In this study, a 10-channel up-converting phosphor technology-based lateral flow (TC-UPT-LF) assay was established for the rapid and simultaneous detection of 10 epidemic foodborne pathogens. Ten different single-target UPT-LF strips were developed and integrated into one TC-UPT-LF disc with optimization. Without enrichment the TC-UPT-LF assay had a detection sensitivity of 104 CFU mL−1 or 105 CFU mL−1 for each pathogen, and after sample enrichment it was 10 CFU/0.6 mg. The assay also showed good linearity, allowing quantitative detection, with a linear fitting coefficient of determination (R2) of 0.916–0.998. The 10 detection channels did not cross-react, so multiple targets could be specifically detected. When 279 real food samples were tested, the assay was highly consistent (100%) with culture-based methods. The results for 110 food samples artificially contaminated with single or multiple targets showed a high detection rate (≥80%) for most target bacteria. Overall, the TC-UPT-LF assay allows the rapid, quantitative, and simultaneous detection of 10 kinds of foodborne pathogens within 20 min, and is especially suitable for the rapid detection and surveillance of foodborne pathogens in food and water. PMID:26884128

Experience with environmental sampling at gas centrifuge enrichment plants

International Nuclear Information System (INIS)

Ekenstam, G. af; Bush, W.; Janov, J.; Kuhn, E.; Ryjinski, M.

2001-01-01

results obtained for two samples taken in May 1997 from the cascade hall at one of the enrichment plants. The evaluation of the results, using model enrichment calculations, showed that at least two enrichment processes had taken place - feeding with natural uranium and with recycled uranium. The effectiveness of environmental sampling was also demonstrated by analyzing a series of swipe samples taken at regular intervals in the process area of a newly commissioned centrifuge enrichment cascade in which the product enrichment was stepwise increased up to 5% 235 U. Experience is still being gained with environmental sampling at centrifuge enrichment plants but it is already considered to be a very useful technique, which allows determining past and current enrichment activities, in particular providing complementary assurance that no clandestine HEU production has occurred. Sampling both inside cascade areas and in cylinder filling and blending areas has proven to be useful and appropriate. A safeguards approach based on the traditional safeguards measures combined with environmental sampling for routine use is under development. This approach will enhance the efficiency of inspector's work in the field and the detection probability for clandestine activities

Modeling and Analysis Methods for an On-line Enrichment Monitor

Energy Technology Data Exchange (ETDEWEB)

Smith, Leon E.; Jarman, Kenneth D.; Wittman, Richard S.; Zalavadia, Mital A.; March-Leuba, Jose A.

2016-05-30

The International Atomic Energy Agency (IAEA) has developed an On-Line Enrichment Monitor (OLEM) as one possible component in a new generation of safeguards measures for uranium enrichment plants. The OLEM measures 235U emissions from the UF6 gas flowing through a unit header pipe using NaI(Tl) spectrometers, and corrects for gas density changes using pressure and temperature sensors in order to determine the enrichment of the gas as a function of time. In parallel with the OLEM instrument development, a Virtual OLEM (VOLEM) software tool has been developed that is capable of producing synthetic gamma-ray, pressure, and temperature data representative of a wide range of enrichment plant operating conditions. VOLEM complements instrument development activities and allows the study of OLEM for scenarios that will be difficult or impossible to evaluate empirically. Uses of VOLEM include: investigation of hardware design options; inter-comparison of candidate gamma-ray spectral analysis and enrichment estimation algorithms; uncertainty budget analysis and performance prediction for typical and atypical operational scenarios; and testing of the OLEM data acquisition, analysis and reporting software. This paper describes the technical foundations of VOLEM and illustrates how it can be used. An overview of the nominal instrument design and deployment scenario for OLEM is provided, with emphasis on the key online-assay measurement challenge: accurately determining the portion of the total 235U signal that comes from a background that includes solid uranium deposits on the piping walls. Monte Carlo modeling tools, data analysis algorithms and uncertainty quantification methods are described. VOLEM is then used to quantitatively explore the uncertainty budgets and predicted instrument performance for a plausible range of typical plant operating parameters, and one set of candidate analysis algorithms. Additionally, a series of VOLEM case studies illustrates how an online

Development of a hand-held fast neutron survey meter

International Nuclear Information System (INIS)

Yoshida, T.; Tsujimura, N.; Yamano, T.

2011-01-01

A neutron survey meter with a ZnS(Ag) scintillator to measure recoil protons was built. The detection probe weighs ∼2 kg, therefore providing us with true portability. Performance tests exhibited satisfactory neutron dosimetry characteristics in unmoderated or lightly moderated fission neutron fields and in particular work environments at a mixed oxide fuel facility. This new survey meter will augment a routine of neutron monitoring that is inconveniently being carried out by moderator-based neutron survey meters. (authors)

Comprehensive evaluation of the Berthold LB1200 survey meter

International Nuclear Information System (INIS)

Davis, M.W.

1986-05-01

The performance of two Berthod LB1200 survey meters was evaluated under the influence of a range of beta and photon radiation energies and environmental conditions likely to be encountered in the field. The survey meters responded satisfactorily to the range of beta particle and photon radiation energies emitted by most radioisotopes commonly used in Canada. The survey meters performed acceptably under most of the environmental conditions tested here with the exception of radiofrequency interference and electrostatic charge

Validation of Folate-Enriched Eggs as a Functional Food for Improving Folate Intake in Consumers

Directory of Open Access Journals (Sweden)

Leslie Altic

2016-11-01

Full Text Available Functional foods enriched with folate may be beneficial as a means of optimizing folate status in consumers. We recently developed novel eggs enriched with folate through folic acid supplementation of the hen’s feed, but their potential to influence consumer folate status is unknown because the natural folate forms incorporated into the eggs may not necessarily be retained during storage and cooking. This study aimed to determine the stability of natural folates in folate-enriched eggs under typical conditions of storage and cooking. Total folate was determined by microbiological assay following tri-enzyme treatment in folate-enriched eggs and un-enriched (barn and free-range on the day they were laid, after storage (up to 27 days and after using four typical cooking methods (boiling, poaching, frying, scrambling for different durations. On the day of laying, the folate content of enriched eggs was found to be significantly higher than that of un-enriched barn or free-range eggs (mean ± SD; 123.2 ± 12.4 vs. 41.2 ± 2.8 vs. 65.6 ± 18.5 µg/100 g; p < 0.001. Storage at refrigerator and room temperature for periods up to the Best Before date resulted in no significant losses to the folate content of folate-enriched eggs. Furthermore, folate in enriched eggs remained stable when cooked by four typical methods for periods up to the maximum cooking time (e.g., 135 ± 22.5, 133.9 ± 23.0 and 132.5 ± 35.1; p = 0.73, for raw, scrambled for 50 s and scrambled for 2 min, respectively. Thus, natural folates in folate-enriched eggs remain highly stable with little or no losses following storage and cooking. These findings are important because they demonstrate the feasibility of introducing folate-enriched eggs into the diet of consumers as functional foods with enriched folate content. Further studies will confirm their effectiveness in optimizing the biomarker folate status of consumers.

The British Gas Quantum Metering System for pre-payment customers

International Nuclear Information System (INIS)

Williams, P.; Fitzpatrick, B.

1992-01-01

The development work leading up to the design of the Quantum Metering System is outlined. The main features of the meter including the reusable tokens, metering equipment, credit charging equipment, central controlling equipment and a portable token reader for field use are described in detail, and the two way communication of information is highlighted. (UK)

On-Line Enrichment Monitor for UF{sub 6} Gas Centrifuge Enrichment Plant

Energy Technology Data Exchange (ETDEWEB)

Ianakiev, K. D.; Boyer, B.; Favalli, A.; Goda, J. M.; Hill, T.; Keller, C.; Lombardi, M.; Paffett, M.; MacArthur, D. W.; McCluskey, C.; Moss, C. E.; Parker, R.; Smith, M. K.; Swinhoe, M. T. [Los Alamos National Laboratory, Los Alamos (United States)

2012-06-15

This paper is a continuation of the Advanced Enrichment Monitoring Technology for UF{sub 6} Gas Centrifuge Enrichment Plant (GCEP) work, presented in the 2010 IAEA Safeguards Symposium. Here we will present the system architecture for a planned side-by-side field trial test of passive (186-keV line spectroscopy and pressure-based correction for UF{sub 6} gas density) and active (186-keV line spectroscopy and transmission measurement based correction for UF{sub 6} gas density) enrichment monitoring systems in URENCO's enrichment plant in Capenhurst. Because the pressure and transmission measurements of UF{sub 6} are complementary, additional information on the importance of the presence of light gases and the UF{sub 6} gas temperature can be obtained by cross-correlation between simultaneous measurements of transmission, pressure and 186-keV intensity. We will discuss the calibration issues and performance in the context of accurate, on-line enrichment measurement. It is hoped that a simple and accurate on-line enrichment monitor can be built using the UF{sub 6} gas pressure provided by the Operator, based on online mass spectrometer calibration, assuming a negligible (a small fraction of percent) contribution of wall deposits. Unaccounted-for wall deposits present at the initial calibration will lead to unwanted sensitivity to changes in theUF{sub 6} gas pressure and thus to error in the enrichment results. Because the accumulated deposits in the cascade header pipe have been identified as an issue for Go/No Go measurements with the Cascade Header Enrichment Monitor (CHEM) and Continuous Enrichment Monitor (CEMO), it is important to explore their effect. Therefore we present the expected uncertainty on enrichment measurements obtained by propagating the errors introduced by deposits, gas density, etc. and will discuss the options for a deposit correction during initial calibration of an On-Line Enrichment Monitor (OLEM).

Remotely metering one million customers in concrete jungle; Telecomptage d'un million d'usagers au milieu d'une jungle de beton

Energy Technology Data Exchange (ETDEWEB)

Kwan, J.Y.C.; Siu, Ph. K.S. [Hong Kong and China Gas Company Limited (China)

2000-07-01

Remote meter reading is probably one of the fastest growing areas for the meter manufacturing industry. There are fixed installation system, RF system, power line signal system etc. Nevertheless, it is rather difficult to have a system in the market that is both cost-effective and suitable for situations like Hong Kong which is full of high rises and concrete jungle. This payer will describe how The Hong Kong and China Gas Company Limited, being the gas utility in Hong Kong serving more than 1.2 million residential customers, successfully comes up with an innovative remote meter reading system which takes advantage of the uniqueness of local gas supply system. Instead of trying to concentrate data from scattering points of the massive piping system through layers of concrete slabs, the new design being developed abandons the traditional spatial RF transmission approach. It utilizes the piping system itself as trunk links to transmit RF signal and negotiate through concrete layers without difficulties. (authors)

What to look for when selecting ANSI protocol meters

Energy Technology Data Exchange (ETDEWEB)

York, T.

2001-09-01

A large number of major manufacturers now offer American National Standards Institute (ANSI) protocol meters, with ever improving capabilities. It is now time to consider ANSI Protocol Meters (APM). One of the advantages of the industry moving toward APMs is the fact that the eventual exclusion of proprietary technology should accelerate and additional software tools should become available to fully support APMs. The emphasis on the part of suppliers and potential users must now be placed on the acquisition of metering products that provide maximum benefits. The proper evaluation of APM will provide valuable feedback to the meter manufacturers, which in turn will encourage the development of new and improved metering products to increase productivity. The customers should be mindful of the following: insist on end device language files, and look for product flexibility. Other interesting features are: billing data (so it can be presented in standard format), present values (for inclusion of instrumentation measurements for quick retrieval by the customer), interval data recording, security features, user defined tables, logging, and power quality monitoring. 1 fig.

Modelling and calibration of a ring-shaped electrostatic meter

Energy Technology Data Exchange (ETDEWEB)

Zhang Jianyong [University of Teesside, Middlesbrough TS1 3BA (United Kingdom); Zhou Bin; Xu Chuanlong; Wang Shimin, E-mail: zhoubinde1980@gmail.co [Southeast University, Sipailou 2, Nanjing 210096 (China)

2009-02-01

Ring-shaped electrostatic flow meters can provide very useful information on pneumatically transported air-solids mixture. This type of meters are popular in measuring and controlling the pulverized coal flow distribution among conveyors leading to burners in coal-fired power stations, and they have also been used for research purposes, e.g. for the investigation of electrification mechanism of air-solids two-phase flow. In this paper, finite element method (FEM) is employed to analyze the characteristics of ring-shaped electrostatic meters, and a mathematic model has been developed to express the relationship between the meter's voltage output and the motion of charged particles in the sensing volume. The theoretical analysis and the test results using a belt rig demonstrate that the output of the meter depends upon many parameters including the characteristics of conditioning circuitry, the particle velocity vector, the amount and the rate of change of the charge carried by particles, the locations of particles and etc. This paper also introduces a method to optimize the theoretical model via calibration.

A Study of the Meters of Bidel Dehlavi\\'s Ghazals(Sonnets and their Comparison with the Meters of Ghazals(Sonnets in Persian and Indian-Style Ghazals(Sonnets

Directory of Open Access Journals (Sweden)

Mahdi Kamali

2010-03-01

Full Text Available Abstract  Bidel Dehlavi ( 1644 A.D./1054 A.H.-1721 A.D./1133 A.H . was one of the most famous Persian poets of India and the greatest poet in Indian branch of a style well-known as Sabk-e Hendi (Indian Style. However, his poems have not sufficiently been studied in Iran .   Meter is one of the basic elements and most effective one in poetry. Therefore, examining the quality of its meter could be one of the basic steps in interpreting and evaluating a poem.   Most of Bidel-readers and Bidel-scholars consider his ghazals as the most valuable product of his wit. Furthermore, according to its history and lyrical nature, ghazal pattern has a closer connection with music and the function of meter in ghazal form is more prominent than that of the others. For this reason, in the present study, first the meters of this poet's ghazals have been introduced and then they are compared with current meters of Persian ghazal and those of the eleventh ( A.H . century. Finally, the metrical features of his ghazals are determined as follows:  Bidel composed 2858 ghazals in 32 different meters, six of which were the most frequent ones in all Persian ghazals and in the eleventh ( A.H . century. In this way, Bidel, whose poems are famous because of their different and unusual quality, significantly conforms four fifth of his ghazals to the standard and thus they are considered "ordinary". But one can see some creativity and experimentation in the meters which are relatively less frequent meters: among the five less frequent meters in Persian poetry, Bidel composed from 1 to 56 ghazals in those meters and 4 ghazals in one meter which, according to the current evidence, there was not such an example known in Persian classical poetry at all.

Status of Net Metering: Assessing the Potential to Reach Program Caps

Energy Technology Data Exchange (ETDEWEB)

Heeter, J.; Gelman, R.; Bird, L.

2014-09-01

Several states are addressing the issue of net metering program caps, which limit the total amount of net metered generating capacity that can be installed in a state or utility service territory. In this analysis, we examine net metering caps to gain perspective on how long net metering will be available in various jurisdictions under current policies. We also surveyed state practices and experience to understand important policy design considerations.

Remote calibration system of a smart electrical energy meter

Directory of Open Access Journals (Sweden)

Zakariae Jebroni

2017-12-01

Full Text Available The need to control the power grid in real time has opened a new field of research, today researchers are trying to design electrical meters that are completely remote controlled, to create an advanced metering infrastructure. One of the most important processes in the field of measurement is the calibration of measuring instruments. The calibration process of the electrical meters was performed at laboratories. However, the new directives, now, require a regular test of accuracy. Nevertheless, moving each time on site to check the accuracy of a meter can be annoying. To solve this problem our contribution is to propose a new structure of a smart meter that integrates a calibration card, so that, this process is carried out remotely. To be able to calibrate the meter or test its accuracy, we have included an AC-AC converter powered by the electrical grid and that provides a stable voltage independent of the electrical grid in term of frequency and amplitude. The output voltage of the converter is used as the reference signal during calibration or accuracy testing. In this paper, we will present the structure of the calibration card, the study and dimensioning of the converter, as well as the control technique used to eliminate variations of the input voltage. At the end, we will present the results of simulations and experiments.

A new kind high-reliability digital reactivity meter

International Nuclear Information System (INIS)

Shen Feng; Jiang Zongbing

2001-01-01

The paper introduces a new kind of high-reliability Digital Reactivity Meter developed by the DRM developing group in designing department of Nuclear Power Institute of China. The meter has two independent measure channels, which can be set as either master-slave structure or working independently. This structure will ensure that the meter can continually fulfill its online measure task under the condition of single failure with it. It provides a solution for the conflict between nuclear station's extreme demand in DRM's reliability and instability of computer's business software platform. The instrument reaches both advance and reliability by covering a lot of kinds of complex functions in data process and display

Gas centrifuge enrichment plants inspection frequency and remote monitoring issues for advanced safeguards implementation

International Nuclear Information System (INIS)

Boyer, Brian David; Erpenbeck, Heather H.; Miller, Karen A.; Ianakiev, Kiril D.; Reimold, Benjamin A.; Ward, Steven L.; Howell, John

2010-01-01

Current safeguards approaches used by the IAEA at gas centrifuge enrichment plants (GCEPs) need enhancement in order to verify declared low enriched uranium (LEU) production, detect undeclared LEU production and detect high enriched uranium (BEU) production with adequate probability using non destructive assay (NDA) techniques. At present inspectors use attended systems, systems needing the presence of an inspector for operation, during inspections to verify the mass and 235 U enrichment of declared cylinders of uranium hexafluoride that are used in the process of enrichment at GCEPs. This paper contains an analysis of how possible improvements in unattended and attended NDA systems including process monitoring and possible on-site destructive analysis (DA) of samples could reduce the uncertainty of the inspector's measurements providing more effective and efficient IAEA GCEPs safeguards. We have also studied a few advanced safeguards systems that could be assembled for unattended operation and the level of performance needed from these systems to provide more effective safeguards. The analysis also considers how short notice random inspections, unannounced inspections (UIs), and the concept of information-driven inspections can affect probability of detection of the diversion of nuclear material when coupled to new GCEPs safeguards regimes augmented with unattended systems. We also explore the effects of system failures and operator tampering on meeting safeguards goals for quantity and timeliness and the measures needed to recover from such failures and anomalies.

Mangrove microniches determine the structural and functional diversity of enriched petroleum hydrocarbon-degrading consortia.

Science.gov (United States)

Gomes, Newton C M; Flocco, Cecilia G; Costa, Rodrigo; Junca, Howard; Vilchez, Ramiro; Pieper, Dietmar H; Krögerrecklenfort, Ellen; Paranhos, Rodolfo; Mendonça-Hagler, Leda C S; Smalla, Kornelia

2010-11-01

In this study, the combination of culture enrichments and molecular tools was used to identify bacterial guilds, plasmids and functional genes potentially important in the process of petroleum hydrocarbon (PH) decontamination in mangrove microniches (rhizospheres and bulk sediment). In addition, we aimed to recover PH-degrading consortia (PHDC) for future use in remediation strategies. The PHDC were enriched with petroleum from rhizosphere and bulk sediment samples taken from a mangrove chronically polluted with oil hydrocarbons. Southern blot hybridization (SBH) assays of PCR amplicons from environmental DNA before enrichments resulted in weak positive signals for the functional gene types targeted, suggesting that PH-degrading genotypes and plasmids were in low abundance in the rhizosphere and bulk sediments. However, after enrichment, these genes were detected and strong microniche-dependent differences in the abundance and composition of hydrocarbonoclastic bacterial populations, plasmids (IncP-1α, IncP-1β, IncP-7 and IncP-9) and functional genes (naphthalene, extradiol and intradiol dioxygenases) were revealed by in-depth molecular analyses [PCR-denaturing gradient gel electrophoresis and hybridization (SBH and microarray)]. Our results suggest that, despite the low abundance of PH-degrading genes and plasmids in the environmental samples, the original bacterial composition of the mangrove microniches determined the structural and functional diversity of the PHDC enriched. © 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

Investigating water meter performance in developing countries: A ...

African Journals Online (AJOL)

High levels of water losses in distribution systems are the main challenge that water utilities in developing countries currently face. The water meter is an essential tool for both the utility and the customers to measure and monitor consumption. When metering is inefficient and coupled with low tariffs, the financial ...

40 CFR 1065.230 - Raw exhaust flow meter.

Science.gov (United States)

2010-07-01

... the following cases, you may use a raw exhaust flow meter signal that does not give the actual value... dew and pressure, p total at the flow meter inlet. Use these values in emission calculations according... CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments Flow-Related Measurements § 1065.230 Raw exhaust...

In vitro and in vivo probiotic assessment of Leuconostoc mesenteroides P45 isolated from pulque, a Mexican traditional alcoholic beverage.

Science.gov (United States)

Giles-Gómez, Martha; Sandoval García, Jorge Giovanni; Matus, Violeta; Campos Quintana, Itzia; Bolívar, Francisco; Escalante, Adelfo

2016-01-01

Pulque is a Mexican traditional alcoholic, non-distilled, fermented beverage produced by the fermentation of the sap, known as aguamiel, extracted from several maguey (Agave) species. Pulque has traditionally been considered a healthy beverage due to its nutrient content and also a traditional medicine for the treatment of gastrointestinal disorders and intestinal infections. During pulque fermentation, the development of acidity, alcohol and viscosity define its final sensorial properties, developing an enriched environment where dominant lactic acid bacteria (LAB), including diverse Leuconostoc species, are present. Because traditional pulque is consumed directly from the fermentation vessel, the naturally associated LAB are ingested and reach the human small intestine alive. Here, we report the in vitro and in vivo probiotic assessment of Leuconostoc mesenteroides strain P45 isolated from pulque. This isolated LAB species exhibited lysozyme, acid (pH 3.5) and bile salts (0.1 and 0.3 % oxgall) resistance. Antibacterial activity against the pathogens Listeria monocytogenes, enteropathogenic Escherichia coli, Salmonella enterica serovar Typhi and S. enterica serovar Typhimurium were observed in assays involving cell-to-cell contact, cell-free 2× concentrated supernatants and cell-to-cell contact under exopolysaccharide-producing conditions. The in vivo probiotic assessment showed an anti-infective activity of L. mesenteroides P45 against S. enterica serovar Typhimurium in challenged male and female BALB/c mice. Analysis of the available genome sequence of strain P45 allowed identified a pre-bacteriocin coding gene and six peptidoglycan hydrolase enzymes, probably involved in the antimicrobial activity of this strain. The results presented in this study support some potential microbial mechanisms associated with the beneficial effects on human health of this LAB involved in the fermentation of pulque.

An assessment of the Italian smart gas metering program

International Nuclear Information System (INIS)

Di Castelnuovo, Matteo; Fumagalli, Elena

2013-01-01

The introduction of smart metering is one of the core elements in recent European policies targeting environmental sustainability and competitiveness of energy markets. Following the roll-out of smart electricity meters, in 2008 the Italian regulator designed an ambitious deployment program also for smart gas meters, that was recently modified in both scope and timing. This paper assesses Italy's original and current deployment plans, with a specific focus on the results of its cost–benefit analysis. In light of the evidence derived from the literature, we observe that the case for the roll-out of smart gas meters in Italy was not supported by a strong emphasis on energy savings but rather focused on increasing efficiency of the Italian gas market; in this respect, we argue that options other than smart gas metering should also be considered. Moreover the Italian cost–benefit analysis, which mostly dealt with the potential cost savings for distributors and suppliers, led to ambiguous results in terms of net present values; thus, we believe that an updated assessment would be extremely useful. Finally, in terms of technological choices, our analysis positively evaluates the regulator's recent proposal to consider a dual-fuel solution for the mass market deployment. - Highlights: • This paper assesses Italy's original and current deployment plans for smart gas meters. • The plan was not supported by a strong emphasis on energy savings. • A focus on increasing efficiency of the Italian gas market appears only partly justifiable. • The business case for adopting smart gas meters should be updated. • Our analysis positively evaluates the a dual-fuel solution for the mass market

Revealing household characteristics from smart meter data

International Nuclear Information System (INIS)

Beckel, Christian; Sadamori, Leyna; Staake, Thorsten; Santini, Silvia

2014-01-01

Utilities are currently deploying smart electricity meters in millions of households worldwide to collect fine-grained electricity consumption data. We present an approach to automatically analyzing this data to enable personalized and scalable energy efficiency programs for private households. In particular, we develop and evaluate a system that uses supervised machine learning techniques to automatically estimate specific “characteristics” of a household from its electricity consumption. The characteristics are related to a household's socio-economic status, its dwelling, or its appliance stock. We evaluate our approach by analyzing smart meter data collected from 4232 households in Ireland at a 30-min granularity over a period of 1.5 years. Our analysis shows that revealing characteristics from smart meter data is feasible, as our method achieves an accuracy of more than 70% over all households for many of the characteristics and even exceeds 80% for some of the characteristics. The findings are applicable to all smart metering systems without making changes to the measurement infrastructure. The inferred knowledge paves the way for targeted energy efficiency programs and other services that benefit from improved customer insights. On the basis of these promising results, the paper discusses the potential for utilities as well as policy and privacy implications. - Highlights: • Many household characteristics can be automatically inferred from smart meter data. • We develop a system to infer employment status and number of occupants, for instance. • We evaluate our system analyzing data collected from 4232 households in Ireland. • The insights enable personalized and scalable efficiency campaigns for utilities. • Energy efficiency measures must be complemented by privacy protection

Smart Metering Guide. Energy Saving and the Customer. Edition 2010

Energy Technology Data Exchange (ETDEWEB)

Kester, J.C.P. (ed.) [Energy research Centre of the Netherlands ECN, Petten (Netherlands); Gonzalez Burgos, M.J. (ed.) [Endesa Ingenieria, Madrid (Spain); Parsons, J. (ed.) [British Electrotechnical and Allied Manufacturers Association BEAMA, London (United Kingdom)

2010-11-15

Smart metering can provide the foundations for a radically different approach to energy reduction schemes. However, the implementation of smart metering is a complex undertaking and its success depends on getting many factors right, from technology choice to how the information is presented to final customers. Making the expected reduction in energy consumption depends on achieving a positive reaction from final customers. Maintaining and increasing these savings will need the engagement of Energy Retailers, energy agencies and others. This Guide has been produced to bring together the lessons learnt from smart metering systems and trials, targeted on the promotion of End Use Energy Efficiency. The aim is to assist those groups who are considering implementing smart metering for this purpose and to maximise the benefits arising from those implementations. . The main target audience for the Guide are utilities, ESCO's and service providers across Europe. In most countries these are the parties investing in the smart metering systems and providing the smart metering services. In addition to these, governments, regulators, consumer bodies and energy agencies, as well as suppliers and system integrators, will also find valuable information in the Guide. As the subtitle of the Guide indicates, the focus of this Guide is on the application of smart metering for delivering energy saving. Making the expected reduction in energy consumption depends on achieving a positive reaction from final customers. In general, the successful provision of smart metering services is highly dependent on the right involvement of the energy final customer. This guide is not a ready-to-go manual for the installation of a specific type of smart metering system. Rather, the authors have tried to give the reader an insight into some of the complexities of the whole implementation process of smart metering systems. Also the guide is impartial regarding different technologies unless there is

Succession of Selected Strains of Acetobacter pasteurianus and Other Acetic Acid Bacteria in Traditional Balsamic Vinegar

OpenAIRE

Gullo, M.; De Vero, L.; Giudici, P.

2009-01-01

The application of a selected Acetobacter pasteurianus strain for traditional balsamic vinegar production was assessed. Genomic DNA was extracted from biofilms after enrichment cultures on GYC medium (10% glucose, 1.0% yeast extract, 2.0% calcium carbonate) and used for PCR/denaturing gradient gel electrophoresis, 16S rRNA gene sequencing, and enterobacterial repetitive intergenic consensus/PCR sequencing. Results suggested that double-culture fermentation is suitable for traditional balsamic...

Enriching semantic knowledge bases for opinion mining in big data applications

OpenAIRE

Weichselbraun, A.; Gindl, S.; Scharl, A.

2014-01-01

This paper presents a novel method for contextualizing and enriching large semantic knowledge bases for opinion mining with a focus on Web intelligence platforms and other high-throughput big data applications. The method is not only applicable to traditional sentiment lexicons, but also to more comprehensive, multi-dimensional affective resources such as SenticNet. It comprises the following steps: (i) identify ambiguous sentiment terms, (ii) provide context information extracted from a doma...

Gamma absorption meter

International Nuclear Information System (INIS)

Dincklage, R.D. von.

1984-01-01

The absorption meter consists of a radiation source, a trough for the absorbing liquid and a detector. It is characterized by the fact that there is a foil between the detector and the trough, made of a material whose binding energy of the K electrons is a little greater than the energy of the photons emitted by the radiation source. The source of radiation and foil are replaceable. (orig./HP) [de

Retention and distribution of polyphenols after pan-frying of French fries in oils enriched with olive leaf extract.

Science.gov (United States)

Chiou, A; Salta, F N; Kalogeropoulos, N; Mylona, A; Ntalla, I; Andrikopoulos, N K

2007-10-01

Palm oil, olive oil, and sunflower oil were supplemented with an extract rich in polyphenols obtained from olive tree (Olea europaea) leaves at levels of 120 and 240 mg total polyphenols per kilogram of oil. Pan-frying of potatoes was performed in both the enriched and the nonsupplemented oils under domestic frying conditions. Total polyphenol content was estimated by the Folin-Ciocalteau assay, oleuropein was determined by HPLC analysis, while other individual polyphenols by GC/MS analysis. Fourteen polyphenol species were identified in the olive leaf extract, among which oleuropein predominated (1.25 g/kg olive leaves). All the enriched oils contained oleuropein before and after frying. Oleuropein as well as other polyphenol species were detected in all French fries cooked in enriched oils. Polyphenol intake by consuming French fries pan-fried in the enriched oils was calculated to be 6 to 31 times higher than that in the case of French fries fried in commercial oils, being dependent on the frying oil type.

Quantitative CrAssphage PCR Assays for Human Fecal ...

Science.gov (United States)

Environmental waters are monitored for fecal pollution to protect public health and water resources. Traditionally, general fecal indicator bacteria are used; however, they cannot distinguish human fecal waste from pollution from other animals. Recently, a novel bacteriophage, crAssphage, was discovered by metagenomic data mining and reported to be abundant in and closely associated with human fecal waste. To confirm bioinformatic predictions, 384 primer sets were designed along the length of the crAssphage genome. Based upon initial screening, two novel crAssphage qPCR assays (CPQ_056 and CPQ_064) were designed and evaluated in reference fecal samples and water matrices. The assays exhibited high specificities (98.6%) when tested against a large animal fecal reference library and were highly abundant in raw sewage and sewage impacted water samples. In addition, CPQ_056 and CPQ_064 assay performance was compared to HF183/BacR287 and HumM2 methods in paired experiments. Findings confirm viral crAssphage qPCR assays perform at a similar level to well established bacterial human-associated fecal source identification technologies. These new viral based assays could become important water quality management and research tools. To inform the public.

Meters and systems for future. Meters fit for retrofitting with a communication module; Zaehler und Systeme fuer die Zukunft. Mit Kommunikationsmodul nachruestbare Zaehler

Energy Technology Data Exchange (ETDEWEB)

Kaiser, Martin [Itron GmbH, Karlsruhe (Germany). Marketing Gas Germany; Sievers, Marco [Allmess GmbH, Oldenburg (Germany). Marketing und Vertrieb Systeme, Wasser- und Waermewirtschaft

2011-04-18

The contribution looks at the situation of smart meters in view of the German government's decision of 2007, which required that smart meters should be installed within a period of six years. However, there is no market-compatible strategy for their introduction, and legal regulations are still lacking. For example, the EnWG demands the obligatory installation of smart meters from 1 January 2010 only in newly constructed or extensively modernized buildings and also on the user's demand.

FUSION OF VENTURI AND ULTRASONIC FLOW METER FOR ENHANCED FLOW METER CHARACTERISTICS USING FUZZY LOGIC

Directory of Open Access Journals (Sweden)

K.V. Santhosh

2015-04-01

Full Text Available This paper proposes a technique for measurement of liquid flow using venturi and ultrasonic flow meter(UFM to have following objectives a to design a multi-sensor data fusion (MSDF architecture for using both the sensors, b improve sensitivity and linearity of venturi and ultrasonic flow meter, and c detect and diagnosis of faults in sensor if any. Fuzzy logic algorithm is used to fuse outputs of both the sensor and train the fuzzy block to produces output which has an improved characteristics in terms of both sensitivity and linearity. For identification of sensor faults a comparative test algorithm is designed. Once trained proposed technique is tested in real life, results show successful implementation of proposed objectives.

Biosensor technology for the detection of illegal drugs I: objectives, preparatory work, and drug enrichment

Science.gov (United States)

Hilpert, Reinhold; Binder, Florian; Grol, Michael; Hallermayer, Klaus; Josel, Hans-Peter; Klein, Christian; Maier, Josef; Oberpriller, Helmut; Ritter, Josef; Scheller, Frieder W.

1994-10-01

In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase and detection by immunological means. This publication covers the description of our objectives, preparatory work and results concerning enrichment of drugs from the gas phase. Vapor pressures of cocaine and cannabinoids have been determined. A test gas generator has been constructed which allows for reproducible preparation of cocaine concentrations between 2 ng/l and 2 pg/l. Coupling of a thermodesorption unit with GC/MS has been established for reference analysis. As another analytical tool, an ELISA with a lower detection limit of about 0,5 pg cocaine/assay has been developed. Applying fleece-type adsorbers, enrichment factors for cocaine in the range of 105 have been realized. No significant interference was found with potentially disturbing substances.

The SmartH2O project: a platform supporting residential water management through smart meters and data intensive modeling

Science.gov (United States)

Cominola, A.; Nanda, R.; Giuliani, M.; Piga, D.; Castelletti, A.; Rizzoli, A. E.; Maziotis, A.; Garrone, P.; Harou, J. J.

2014-12-01

Designing effective urban water demand management strategies at the household level does require a deep understanding of the determinants of users' consumption. Low resolution data on residential water consumption, as traditionally metered, can only be used to model consumers' behavior at an aggregate level whereas end uses breakdown and the motivations and individual attitudes of consumers are hidden. The recent advent of smart meters allows gathering high frequency consumption data that can be used both to provide instantaneous information to water utilities on the state of the network and continuously inform the users on their consumption and savings. Smart metered data also allow for the characterization of water end uses: this information, coupled with users' psychographic variables, constitutes the knowledge basis for developing individual and multi users models, through which water utilities can test the impact of different management strategies. SmartH2O is an EU funded project which aims at creating an ICT platform able to (i) capture and store quasi real time, high resolution residential water usage data measured with smart meters, (ii) infer the main determinants of residential water end uses and build customers' behavioral models and (iii) predict how the customer behavior can be influenced by various water demand management strategies, spanning from dynamic water pricing schemes to social awareness campaigns. The project exploits a social computing approach for raising users' awareness about water consumption and pursuing water savings in the residential sector. In this work, we first present the SmartH2O platform and data collection, storage and analysis components. We then introduce some preliminary models and results on total water consumption disaggregation into end uses and single user behaviors using innovative fully automated algorithms and overcoming the need of invasive metering campaigns at the fixture level.

Bacterial Community Profiling of H2/CO2 or Formate-Utilizing Acetogens Enriched from Diverse Ecosystems

Science.gov (United States)

Han, R.; Zhang, L.; Fu, B.; Liu, H.

2014-12-01

Synthetic gases are usually generated from either cellulosic agricultural waste combustion or industrial release and could be subsequently transformed into acetate, ethanol, and/or butyrate by homoacetogenic bacteria, which commonly possess reductive acetyl-CoA synthesis pathway. Homoacetogen-based syngas fermentation technology provides an alternative solution to link greenhouse gas emission control and cellulosic solid waste treatment with biofuels production. The objective of our current project is to hunt for homoacetogens with capabilities of highly efficiently converting syngases to chemical solvents. In this study, we evaluated homoacetogens population dynamics during enrichments and pinpointed dominant homoacetogens representing diverse ecosystems enriched by different substrates. We enriched homoacetogens from four different samples including waste activate sludge, freshwater sediment, anaerobic methanogenic sludge, and cow manure using H2/CO2 (4:1) or formate as substrate for homoacetogen enrichment. Along with the formyltetrahydrofolate synthetase (FTHFS) gene (fhs gene)-specific real time qPCR assay and Terminal Restriction Fragment Length Polymorphism (T-RFLP) analysis, 16S rRNA based 454 high-throughput pyrosequencing was applied to reveal the population dynamic and community structure during enrichment from different origins. Enrichment of homoacetogenic populations coincided with accumulations of short chain fatty acids such as acetate and butyrate. 454 high-throughput pyrosequencing revealed Firmicutes and Spirochaetes populations became dominant while the overall microbial diversity decreased after enrichment. The most abundant sequences among the four origins belonged to the following phyla: Firmicutes, Spirochaetes, Proteobacteria, and Bacteroidetes, accounting for 62.1%-99.1% of the total reads. The major putative homoacetogenic species enriched on H2/CO2 or formate belonged to Clostridium spp., Acetobacterium spp., Acetoanaerobium spp

Evaluation of the Thermo Scientific SureTect Listeria monocytogenes Assay.

Science.gov (United States)

Cloke, Jonathan; Leon-Velarde, Carlos; Larson, Nathan; Dave, Keron; Evans, Katharine; Crabtree, David; Hughes, Annette; Hopper, Craig; Simpson, Helen; Withey, Sophie; Oleksiuk, Milena; Holopainen, Jani; Wickstrand, Nina; Kauppinen, Mikko

2014-01-01

The Thermo Scientific SureTect Listeria monocytogenes Assay is a new real-time PCR assay for the detection of Listeria monocytogenes in food and environmental samples. This assay was validated using the AOAC Research Institute (AOAC-RI) Performance Tested Methods program in comparison to the reference method detailed in International Organization for Standardization 11290-1:1996, including Amendment 1:2004 with the following foods and food contact surfaces: smoked salmon, processed cheese, fresh bagged spinach, fresh cantaloupe, cooked prawns (chilled product), cooked sliced turkey meat (chilled product), ice cream, pork frankfurters, salami, ground raw beef meat (12% fat), plastic, and stainless steel. All matrixes were tested by Thermo Fisher Scientific, Microbiology Division, Basingstoke, UK. In addition, three matrixes (pork frankfurters, bagged lettuce, and stainless steel) were analyzed independently as part of the AOAC-RI controlled laboratory study by the University of Guelph, Canada. Using probability of detection (POD) statistical analysis, a significant difference was demonstrated between the candidate and reference methods for salami, cooked sliced turkey and ice cream in favor of the SureTect assay. For all other matrixes, no significant difference by POD was seen between the two methods during the study. Inclusivity and exclusivity testing was also conducted with 53 and 30 isolates, respectively, which demonstrated that the SureTect assay was able to detect all serotypes of L. monocytogenes. None of the exclusivity isolates analyzed were detected by the SureTect assay. Ruggedness testing was conducted to evaluate the performance of the assay with specific method deviations outside the recommended parameters open to variation, i.e., enrichment time and temperature and lysis temperature, which demonstrated that the assay gave reliable performance. Accelerated stability testing was also conducted, validating the assay shelf life.

The Anti-RFI Design of Intelligent Electric Energy Meters with UHF RFID

Science.gov (United States)

Chen, Xiangqun; Huang, Rui; Shen, Liman; chen, Hao; Xiong, Dezhi; Xiao, Xiangqi; Liu, Mouhai; Xu, Renheng

2018-03-01

In order to solve the existing artificial meter reading watt-hour meter industry is still slow and inventory of common problems, using the uhf radio frequency identification (RFID) technology and intelligent watt-hour meter depth fusion, which has a one-time read multiple tags, identification distance, high transmission rate, high reliability, etc, while retaining the original asset management functions, in order to ensure the uhf RFID and minimum impact on the operation of the intelligent watt-hour meter, proposed to improve the stability of the electric meter system while working at the same time, this paper designs the uhf RFID intelligent watt-hour meter radio frequency interference resistance, put forward to improve intelligent watt-hour meter electromagnetic compatibility design train of thought, and introduced its power and the hardware circuit design of printed circuit board, etc.

Five training sessions improves 3000 meter running performance.

Science.gov (United States)

Riiser, A; Ripe, S; Aadland, E

2015-12-01

The primary aim of the present study was to evaluate the effect of two weeks of endurance training on 3000-meter running performance. Secondary we wanted to assess the relationship between baseline running performance and change in running performance over the intervention period. We assigned 36 military recruits to a training group (N.=28) and a control group. The training group was randomly allocated to one of three sub-groups: 1) a 3000 meter group (test race); 2) a 4x4-minutes high-intensity interval group; 3) a continuous training group. The training group exercised five times over a two-week period. The training group improved its 3000 meter running performance with 50 seconds (6%) compared to the control group (P=0.003). Moreover, all sub-groups improved their performance by 37 to 73 seconds (4-8%) compared to the control group (Ptraining group. We conclude that five endurance training sessions improved 3000 meter running performance and the slowest runners achieved the greatest improvement in running performance.

Atomics international fuel fabrication facility and low enrichment program [contributed by H.W. Hassel, NUKEM

International Nuclear Information System (INIS)

Hassel, H.W.

1993-01-01

NUKEM handles around almost two tons of highly enriched uranium a year and it was necessary to satisfy all the new physical protection philosophies. That means that we have to install storage and safe fabrication sites for a lot of money, 25 meter thick concrete walls, and different alarm systems. So just to demonstrate how silly this business is, we have just overcome this for highly enriched uranium, and now we speak about low enriched uranium for which we don't need all of these investments to make this business safe. I would-just like to concentrate my words on the status of fabrication and considerations in my company concerning the medium enriched uranium and low enriched uranium. In the table are the different fuel types (see column) and then we have the fabrication in column 2 the experience of my comp any in kg. In column 3 is the irradiation experience of these fuels types. Column 4 shows the studies and calculations made in our company for lower and medium enriched fuels. The preliminary fabrication tests and calculations are in column 5, and in column 6 we have the delivery time for a prototype core in months after UF 6 supply. Column 7 shows the time for the development of specifications including irradiation time in years for 6 and 7 and column is the estimated cost of 6 and 7 There is just one fuel that is not in this summary and that is U-Zr. We now see how complex and sophisticated this business is. I have told you already that we have installed for a lot of millions of Deutsche Mark the physical protection, storage vaults and things like that. Now we have to investigate all these different types of fuels for, as you see, a lot of money. Maybe these are a lot of optimistic figures; anyway the question is, does this make all the overall nuclear situation worldwide easier or not. One cannot answer for the moment, but anyway we have a lot of problems

Metering instrument of quality factor Q of gravitational wave antenna

International Nuclear Information System (INIS)

Jia-yan, C.; Tong-ren, G.

1982-01-01

The quality factor, Q, of gravitational wave antenna depends on the material property as well as external conditions, such as temperature, residual pressure in vacuum tank, support type, additional loss from transducer on antenna, etc. In order to find out the relationship between the antenna Q and external conditions automatical operating in succession is required. The authors have designed and made a metering instrument for quality factor Q. The metering instrument of Q can measure Q of the metal cylinder and other bar of higher Q. It can give data of the measurement at regular intervals as desired. It can measure accurately the longitudinal fundamental mode frequency of the cylinder with a digital frequency meter record oscillating signal from metering instrument. Because the metering instrument excites free-vibration of the cylinder with free-running type and keep up the stationary amplitude for a long time. (Auth.)

Investigation of Seepage Meter Measurements in Steady Flow and Wave Conditions.

Science.gov (United States)

Russoniello, Christopher J; Michael, Holly A

2015-01-01

Water exchange between surface water and groundwater can modulate or generate ecologically important fluxes of solutes across the sediment-water interface. Seepage meters can directly measure fluid flux, but mechanical resistance and surface water dynamics may lead to inaccurate measurements. Tank experiments were conducted to determine effects of mechanical resistance on measurement efficiency and occurrence of directional asymmetry that could lead to erroneous net flux measurements. Seepage meter efficiency was high (average of 93%) and consistent for inflow and outflow under steady flow conditions. Wave effects on seepage meter measurements were investigated in a wave flume. Seepage meter net flux measurements averaged 0.08 cm/h-greater than the expected net-zero flux, but significantly less than theoretical wave-driven unidirectional discharge or recharge. Calculations of unidirectional flux from pressure measurements (Darcy flux) and theory matched well for a ratio of wave length to water depth less than 5, but not when this ratio was greater. Both were higher than seepage meter measurements of unidirectional flux made with one-way valves. Discharge averaged 23% greater than recharge in both seepage meter measurements and Darcy calculations of unidirectional flux. Removal of the collection bag reduced this net discharge. The presence of a seepage meter reduced the amplitude of pressure signals at the bed and resulted in a nearly uniform pressure distribution beneath the seepage meter. These results show that seepage meters may provide accurate measurements of both discharge and recharge under steady flow conditions and illustrate the potential measurement errors associated with dynamic wave environments. © 2014, National Ground Water Association.

Smart meter adoption and deployment strategy for residential buildings in Indonesia

International Nuclear Information System (INIS)

Chou, Jui-Sheng; Gusti Ayu Novi Yutami, I

2014-01-01

Highlights: • Limited consumer awareness of smart meters contributes to skepticism. • Data obtained from a survey of energy users are analyzed using SEM. • A CAP index is developed via SEM results to measure consumer propensity for adopting smart meters. • The findings of this study enhance understanding of consumer perceptions and behaviors. • Concrete strategies are proposed to help policy makers and utility companies. - Abstract: For countries pursuing sustainable development and energy efficiency, the use of smart meters is considered a first step in allowing residential consumers to remotely control their energy consumption, and a promising technology for conserving limited energy resources. However, despite the growing interest in smart meters, limited consumer awareness, knowledge, and understanding of these devices contributes to skepticism. This study thus developed an index to measure consumer propensity to adopt smart meters in residential buildings. Data obtained from a survey of energy use by Indonesian households were analyzed using structural equation modeling to determine the interacting factors in consumer acceptance of smart meters. Consumer perceptions, expectations, and intentions regarding the potential use of smart meters in Indonesia were also discussed. The findings of this study enhance understanding of consumer perceptions and behaviors, and can help decision makers and energy utility companies develop policies and strategies for a “one-size-fits-all” program related to smart meter applications in future residential buildings

Designing remote web-based mechanical-volumetric flow meter ...

African Journals Online (AJOL)

Today, in water and wastewater industry a lot of mechanical-volumetric flow meters are used for the navigation of the produced water and the data of these flow meters, due to use in a wide geographical range, is done physically and by in person presence. All this makes reading the data costly and, in some cases, due to ...

Uranium enrichment

International Nuclear Information System (INIS)

Mohrhauer, H.

1982-01-01

The separation of uranium isotopes in order to enrich the fuel for light water reactors with the light isotope U-235 is an important part of the nuclear fuel cycle. After the basic principals of isotope separation the gaseous diffusion and the centrifuge process are explained. Both these techniques are employed on an industrial scale. In addition a short review is given on other enrichment techniques which have been demonstrated at least on a laboratory scale. After some remarks on the present situation on the enrichment market the progress in the development and the industrial exploitation of the gas centrifuge process by the trinational Urenco-Centec organisation is presented. (orig.)

United States uranium enrichment policies

International Nuclear Information System (INIS)

Roberts, R.W.

1977-01-01

ERDA's uranium enrichment program policies governing the manner in which ERDA's enrichment complex is being operated and expanded to meet customer requirements for separative work, research and development activities directed at providing technology alternatives for future enrichment capacity, and establishing the framework for additional domestic uranium enrichment capacity to meet the domestic and foreign nuclear industry's growing demand for enrichment services are considered. The ERDA enrichment complex consists of three gaseous diffusion plants located in Oak Ridge, Tennessee; Paducah, Kentucky; and Portsmouth, Ohio. Today, these plants provide uranium enrichment services for commercial nuclear power generation. These enrichment services are provided under contracts between the Government and the utility customers. ERDA's program involves a major pilot plant cascade, and pursues an advanced isotope separation technique for the late 1980's. That the United States must develop additional domestic uranium enrichment capacity is discussed

Squid based beam current meter

International Nuclear Information System (INIS)

Kuchnir, M.

1983-01-01

A SQUID based beam current meter has the capability of measuring the current of a beam with as little as 30 x 155 antiprotons (with a signal to noise ratio of 2). If low noise dc current is used to cancel most of the beam or an up-down counter is used to count auto-resets this sensitivity will be available at any time in the acumulation process. This current meter will therefore be a unique diagnostic tool for optimizing the performance of several Tev I components. Besides requiring liquid helium it seems that its only drawback is not to follow with the above sensitivity a sudden beam change larger than 16 μA, something that could be done using a second one in a less sensitive configuration

Blueprint for domestic uranium enrichment

International Nuclear Information System (INIS)

1981-01-01

The AEC advisory committee on domestic production of uranium enrichment has studied for more than a year how to achieve the domestic enrichment of uranium by the construction and operation of a commercial enriching plant using centrifugal separation method, and the report was submitted to the Atomic Energy Commission on August 18, 1980. Japan has depended wholly on overseas services for her uranium enrichment needs, but the development of domestic enrichment has been carried on in parallel. The AEC decided to construct a uranium enrichment pilot plant using centrifuges, and it has been forwarded as a national project. The plant is operated by the Power Reactor and Nuclear Fuel Development Corp. since 1979. The capacity of the plant will be raised to approximately 75 ton SWU a year. The centrifuges already operated have provided the first delivery of fuel of about 1 ton for the ATR ''Fugen''. The demand-supply balance of uranium enrichment service, the significance of the domestic enrichment of uranium, the evaluation of uranium enrichment technology, the target for domestic enrichment plan, the measures to promote domestic uranium enrichment, and the promotion of the construction of a demonstration plant are reported. (Kako, I.)

Antimicrobial Activity of Chitosan Film Forming Solution Enriched with Essential Oils; an in Vitro Assay.

Science.gov (United States)

Raphaël, Kana Jean; Meimandipour, Amir

2017-01-01

Background: The resistance of the bacteria and fungi to the innumerous antimicrobial agents is a major challenge in the treatment of the infections demands to the necessity for searching and finding new sources of substances with antimicrobial properties. The incorporation of the essential oils (EOs) in chitosan film forming solution may enhance antimicrobial properties. However, its use as the feeding additive in the poultry nutrition needs to clarify the product's activity against both pathogen and the useful microbes in the gastrointestinal tract. Objectives: In the present study, we carried out an in vitro investigation and evaluated the antimicrobial activity of chitosan film forming solution incorporated with essential oils (CFs+EOs) against microbial strains including Staphylococcus aureus, Escherichia coli, Enterococcus faecium, Lactobacillus rahmnosus, Aspergillus niger and Alternaria alternate . Material and Methods: In three replicates, the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of different treatments including: 1- essential oils (EOs), 2- chitosan film solution (CFs), and 3-chitosan film solution enriched with EOs (CFs+EOs) were determined against above mentioned microbes. Results: The results indicated that the chitosan solution enriched with essential oils (CFs+EOs) is capable of inhibiting the bacterial and fungal growth even at the lowest concentrations. The MIC and MBC for all the antimicrobial agents against Escherichia coli and Staphylococcus aureus were very low compared to the concentrations needed to inhibit the growth of useful bacteria, Lactobacillus rahmnosu and Enterococcus faecium . The antifungal activity of chitosan was enhanced as the concentration of EOs increased in the film solution. Conclusion: Chitosan-EOs complexes are the promising candidate for novel contact antimicrobial agents that can be used in animal feeds.

The Thirty-Meter Telescope

Indian Academy of Sciences (India)

2016-01-27

Jan 27, 2016 ... The Thirty-Meter Telescope international observatory will enable transformational observations over the full cosmic timeline all the way from the first luminous objects in the Universe to the planets and moons of our own solar system. To realize its full scientific potential, TMT will be equipped with a powerful ...

Development of a real-time PCR melt curve assay for simultaneous detection of virulent and antibiotic resistant Salmonella.

Science.gov (United States)

Singh, Prashant; Mustapha, Azlin

2014-12-01

Multiple drug resistance in Salmonella is an emerging problem in the area of food safety. Depending on the virulence and antibiotic resistance characteristics of the Salmonella strain, infections of varying severity could result. In this study, a multiplex melt curve real-time PCR assay for the detection of virulent and antibiotic resistance strains of Salmonella was developed with two primer sets. The first set targets the virulence gene, invasin (invA), and tetracycline (tetG), streptomycin (aadA2) and sulphonamide (sulI) antibiotic resistance genes, and the second set amplifies ampicillin (blaPSE,blaTEM) and chloramphenicol (floR) resistance genes. The multiplex assay was evaluated using 41 Salmonella strains and was further tested on eight different artificially inoculated food samples. The fluorescent DNA intercalating dye, SYTO9, generated high resolution melt curve peaks and, hence, was used for the development of the assay. This multiplex assay worked efficiently over a DNA concentration range of 20 ng-200 fg and showed a sensitivity of 290 CFU/mL with serially diluted broth cultures. The detection limit for un-enriched artificially inoculated food samples was 10(4) CFU/g, but an enrichment period of 6 h allowed for detection of 10 CFU/g of cells in the samples. Copyright © 2014 Elsevier Ltd. All rights reserved.

Activity meters: Calibration and quality assurance measures by the manufacturer

International Nuclear Information System (INIS)

Pychlau, P.

1992-01-01

A manufacturer of ionisation chambers gives a general idea of such quality assurance programs as may be implemented after an agreement has been reached at the EC level on a guideline for activity meters. Further issues discussed include the final controls, calibration of activity meters by the manufacturer and the advantages that the participation in cooperate tests would offer over a mandatory calibration of activity meters. (orig./DG) [de

Powering the planet : smart meters : a practitioner's perspective

Energy Technology Data Exchange (ETDEWEB)

Smith, W. [Siemens Canada Ltd., Burnaby, BC (Canada)

2006-07-01

The role of smart metering as an energy solution to increased demand was discussed from the perspective of Siemens Canada Ltd. Global megatrends such as increased urbanization, resource scarcity and a greater focus on environmental issues is changing the energy landscape, and many electricity industry leaders are now recognizing the importance of integrated energy solutions. Electric power supply will need to combine economy with security and environmental concern, particularly as utility operations plan up to 10 years in advance of current peak requirements. It is expected that smart metering can postpone capital investment through supply and demand balancing, and will also be used by utilities to remove subsidy and increase customer accountability. While smart metering may seem to respond to environmental requirements and pressures, it is not yet known whether smart metering will change customer behaviour significantly or reduce energy costs. However, the alignment between retail and distribution may create regional advantages by enabling more advanced product offerings in load management and profiling. While smart metering is a proven technology, market operation and back office processes have yet to be determined. Segmentation may prove to be a critical implementation factor which will require an in-depth evaluation of geography; technology; consumption; conservation; and payback. Data availability must be balanced with communications costs. Low cost, low functionality smart meters will enable centralized control. Low cost online communications can allow remote operation of the meter point including real time functions. It was concluded that a centralized scheme operation will enable all points to be managed within a single portfolio, and create significant cost reduction opportunities in meter operations. Rather than investing in complicated technology that may become obsolete, Siemens will rely instead on the creation of a service model that will allow

Mobile metering. Efficient charging infrastructure. Charging stations in the public, semi-public and private room; Mobile Metering. Effiziente Ladeinfrastruktur. Ladepunkte im oeffentlichen, halboeffentlichen und privaten Raum

Energy Technology Data Exchange (ETDEWEB)

Hoerhammer, Marcus; Zayer, Peter [Voltaris GmbH, Merzig (Germany); Hechtfischer, Knut; Pawlitschek, Frank [Ubitricity Gesellschaft fuer Verteilte Energiesysteme mbH, Berlin (Germany)

2013-01-28

Mobile metering shifts the power metering and data communication from the stationary charging stationary into the charger cable or into the vehicle - and thus creates a mobile metering point. Thus, the charging stations are reduced to technically simple system sockets. These system sockets do not cause current expenses and make the charging infrastructure affordable and economically viable.

Evaluation of gamma spectroscopy gauge for uranium-plutonium assay

International Nuclear Information System (INIS)

Notea, A.; Segal, Y.

1975-01-01

A procedure is presented for the characterization of a gamma passive method for nondestructive analysis of nuclear fuel. The approach provides an organized and systematic way for optimizing the assay system. The key function is the relative resolving power defined as the smallest relative change in the Quantity of radionuclide measured, that may be detected within a certain confidence level. This function is derived for nuclear fuel employing a model based on empirical parameters. The ability to detect changes in fuels of binary and trinary compositions with a 50 cc Ge(Li) at a 1 min counting period is discussed. As an example to a binary composition, an enriched uranium fuel was considered. The 185 keV and 1001 keV gamma lines are used for the assay of 235 U and 238 U respectively. As a trinary composition a plutonium-containing gamma line. The interference of the high energy lines is carefully analyzed, and numerical results are presented. For both cases the range of measurement under specific accuracy demands is determined. The approach described is suitable also for evaluation of other passive as well as active assay methods. (author)