WorldWideScience

Sample records for total deviatoric stress

  1. Deviatoric stress: a nuisance or a gold mine?

    International Nuclear Information System (INIS)

    Bassett, W A

    2006-01-01

    Both synchrotron radiation and deviatoric stress were once considered to be nuisances. Now synchrotron radiation is one of the most important tools available to scientists of all disciplines and deviatoric stress is one of the most useful aspects of x-ray diffraction at extreme conditions. Samples in high-pressure devices are under true hydrostatic pressure only when surrounded by a fluid, thus limiting true hydrostatic pressure studies at ambient temperatures to pressures below about 11 GPa. Elevated temperature is able to extend this limit but has rarely been used for this purpose. Instead, noble gases have been used as pressure media as their solids are especially soft. Deviatoric stress and resultant anisotropic elastic strain in solid samples and solid media have led to many subtle errors in determinations of elastic properties and crystal structures, especially in the days before it was realized that they could be measured and were potentially a valuable source of information. In recent years, measuring anisotropic elastic strain by x-ray diffraction has provided new insights into materials strength, elastic properties, crystal structures, mechanisms of phase transitions, slip systems, lattice preferred orientation, and, of course, ways to make corrections when deviatoric stress is indeed a nuisance

  2. Triaxial Wetting Test on Rockfill Materials under Stress Combination Conditions of Spherical Stress p and Deviatoric Stress q

    Directory of Open Access Journals (Sweden)

    Yan-yi Zhang

    2018-01-01

    Full Text Available A GCTS medium-sized triaxial apparatus is used to conduct a single-line method wetting test on three kinds of rockfill materials of different mother rocks such as mixture of sandstone and slate, and dolomite and granite, and the test stress conditions is the combination of spherical stress p and deviatoric stress q. The test results show that (1 for wetting shear strain, the effects of spherical stress p and deviatoric stress q are equivalent, and wetting shear strain and deviatoric stress q show the power function relationship preferably. (2 For wetting volumetric strain, the effect of deviatoric stress q can be neglected because it is extremely insignificant, and spherical stress p is the main influencing factor and shows the power function relationship preferably. (3 The wetting strains decrease significantly with the increase in initial water content and sample density generally, but the excessively high dry density will increase the wetting deformation. Also, the wetting strains will decrease with the increase in the saturated uniaxial compressive strength and average softening coefficient of the mother rock. Based on the test results, a wetting strain model is proposed for rockfill materials. The verification results indicate that the model satisfactorily reflects the development law of wetting deformation.

  3. Effects of deviatoric stress and radial strain on the shock-induced diffusionless transformation in boron nitride

    International Nuclear Information System (INIS)

    Sekine, T.; Kobayashi, T.; Nameki, H.

    1997-01-01

    The phase transformation of graphitelike BN (h-BN) to wurtzite-type high-pressure BN (w-BN) was investigated through shock-recovery techniques under quasihydrodynamic and nonhydrodynamic shock compressions and under various strain conditions. The experimental results support a diffusionless mechanism, by which the hydrodynamic c-axis compression of h-BN is preferred. This mechanism is topologically considered based on the relationship of crystal structures between h-BN and w-BN. The presence of deviatoric stress and strain depresses the yield of w-BN and the development of w-BN (100) relative to (002). copyright 1997 American Institute of Physics

  4. The deviatoric response of three dense glasses under shock loading conditions

    International Nuclear Information System (INIS)

    Radford, D.D.; Proud, W.G.; Field, J.E.

    2002-01-01

    In-material longitudinal and lateral stress histories in three dense, silica-based glasses were directly measured by embedded manganin stress gauges during plate impact experiments. Lateral stress profiles in all of the materials show evidence of failure fronts that behave in a similar manner to those observed in open-structured glasses. The measured stress histories were used to calculate the deviatoric responses and results indicate that ahead of the failure front the shear stress increases linearly along the estimated elastic response. Behind the failure front, however, the shear stress appears to first decrease and then increase as the pressure increases, contrary to a previous interpretation

  5. Pre-earthquake signals – Part I: Deviatoric stresses turn rocks into a source of electric currents

    Directory of Open Access Journals (Sweden)

    F. T. Freund

    2007-09-01

    Full Text Available Earthquakes are feared because they often strike so suddenly. Yet, there are innumerable reports of pre-earthquake signals. Widespread disagreement exists in the geoscience community how these signals can be generated in the Earth's crust and whether they are early warning signs, related to the build-up of tectonic stresses before major seismic events. Progress in understanding and eventually using these signals has been slow because the underlying physical process or processes are basically not understood. This has changed with the discovery that, when igneous or high-grade metamorphic rocks are subjected to deviatoric stress, dormant electronic charge carriers are activated: electrons and defect electrons. The activation increases the number density of mobile charge carriers in the rocks and, hence, their electric conductivity. The defect electrons are associated with the oxygen anion sublattice and are known as positive holes or pholes for short. The boundary between stressed and unstressed rock acts a potential barrier that lets pholes pass but blocks electrons. Therefore, like electrons and ions in an electrochemical battery, the stress-activated electrons and pholes in the "rock battery" have to flow out in different directions. When the circuit is closed, the battery currents can flow. The discovery of such stress-activated currents in crustal rocks has far-reaching implications for understanding pre-earthquake signals.

  6. A Family of Invariant Stress Surfaces

    DEFF Research Database (Denmark)

    Krenk, S.

    A family of invariant stress surfaces with a cubic dependence on the deviatoric stress components is expressed as a linear combination of the second and third deviatori stress invariants. A simple geometric derivation demonstrates the convexity of the contours in the deviatoric plane. An explicit...... representation of the deviatoric contours in terms of a size and a shape parameter is given. The shape parameter effects a continuous transition from a triangle to a circle in the deviatoric plane. An explicit format in terms of the triaxial compresson and tension generators is derived, and the plane stress...

  7. Crack propagation model taking into consideration the local effect of the deviatoric stress and the non-local effect of the isotropic stress

    Czech Academy of Sciences Publication Activity Database

    Kafka, Vratislav

    2011-01-01

    Roč. 56, č. 4 (2011), s. 343-358 ISSN 0001-7043 R&D Projects: GA ČR(CZ) GA103/09/2101 Institutional research plan: CEZ:AV0Z20710524 Keywords : crack propagation * nonlocal effect * deviatoric local effect * isotropic nonlocal Subject RIV: BM - Solid Matter Physics ; Magnetism

  8. On Rayleigh waves in a thinly layered laminated thermoelastic medium with stress couples under initial stresses

    Directory of Open Access Journals (Sweden)

    Pijush Pal Roy

    1988-01-01

    Full Text Available A study is made of the propagation of Rayleigh waves in a thinly layered laminated thermoelastic medium under deviatoric, hydrostatic, and couple stresses. The frequency equation of the Rayleigh waves is obtained. The phase velocity of the Rayleigh waves depends on the initial stress, deviatoric stress, and the couple stress. The laminated medium is first replaced by an equivalent anisotropic thermoelastic continuum. The corresponding thermoelastic coefficients (after deformation are derived in terms of initially isotropic thermoelastic coefficients (before deformation of individual layers. Several particular cases are discussed for the determination of the displacement fields with or without the effect of the couple stress.

  9. Stress field models from Maxwell stress functions: southern California

    Science.gov (United States)

    Bird, Peter

    2017-08-01

    The lithospheric stress field is formally divided into three components: a standard pressure which is a function of elevation (only), a topographic stress anomaly (3-D tensor field) and a tectonic stress anomaly (3-D tensor field). The boundary between topographic and tectonic stress anomalies is somewhat arbitrary, and here is based on the modeling tools available. The topographic stress anomaly is computed by numerical convolution of density anomalies with three tensor Green's functions provided by Boussinesq, Cerruti and Mindlin. By assuming either a seismically estimated or isostatic Moho depth, and by using Poisson ratio of either 0.25 or 0.5, I obtain four alternative topographic stress models. The tectonic stress field, which satisfies the homogeneous quasi-static momentum equation, is obtained from particular second derivatives of Maxwell vector potential fields which are weighted sums of basis functions representing constant tectonic stress components, linearly varying tectonic stress components and tectonic stress components that vary harmonically in one, two and three dimensions. Boundary conditions include zero traction due to tectonic stress anomaly at sea level, and zero traction due to the total stress anomaly on model boundaries at depths within the asthenosphere. The total stress anomaly is fit by least squares to both World Stress Map data and to a previous faulted-lithosphere, realistic-rheology dynamic model of the region computed with finite-element program Shells. No conflict is seen between the two target data sets, and the best-fitting model (using an isostatic Moho and Poisson ratio 0.5) gives minimum directional misfits relative to both targets. Constraints of computer memory, execution time and ill-conditioning of the linear system (which requires damping) limit harmonically varying tectonic stress to no more than six cycles along each axis of the model. The primary limitation on close fitting is that the Shells model predicts very sharp

  10. The Effect of Pressure and Deviatoric Stress on Rock Magnetism

    Science.gov (United States)

    1988-10-31

    34 I 0 z 0.6 I 0.5 0 50 100 150 200 PRESSURE, MPaI 1.0 UNIAXIAL STRESS H0.9 z U 0.8 Lw 0.7 I 0 .6 I Z 0.5 .. m 0.4 ’ ’ ’ 0 50 100 150 200 m STRESS...DIFFERENCE, MPaI Figure 2-1. Normalized TRM is shown as a function of pressure or stress difference for the first loading cycle on diabase specimens. The

  11. Viscosity, granular-temperature, and stress calculations for shearing assemblies of inelastic, frictional disks

    International Nuclear Information System (INIS)

    Walton, O.R.; Braun, R.L.

    1986-01-01

    Employing nonequilibrium molecular-dynamics methods the effects of two energy loss mechanisms on viscosity, stress, and granular-temperature in assemblies of nearly rigid, inelastic frictional disks undergoing steady-state shearing are calculated. Energy introduced into the system through forced shearing is dissipated by inelastic normal forces or through frictional sliding during collisions resulting in a natural steady-state kinetic energy density (granular-temperature) that depends on the density and shear rate of the assembly and on the friction and inelasticity properties of the disks. The calculations show that both the mean deviatoric particle velocity and the effective viscosity of a system of particles with fixed friction and restitution coefficients increase almost linearly with strain rate. Particles with a velocity-dependent coefficient of restitution show a less rapid increase in both deviatoric velocity and viscosity as strain rate increases. Particles with highly dissipative interactions result in anisotropic pressure and velocity distributions in the assembly, particularly at low densities. At very high densities the pressure also becomes anisotropic due to high contact forces perpendicular to the shearing direction. The mean rotational velocity of the frictional disks is nearly equal to one-half the shear rate. The calculated ratio of shear stress to normal stress varies significantly with density while the ratio of shear stress to total pressure shows much less variation. The inclusion of surface friction (and thus particle rotation) decreases shear stress at low density but increases shear stress under steady shearing at higher densities

  12. Energetical and multiscale approaches for the definition of an equivalent stress for magneto-elastic couplings

    International Nuclear Information System (INIS)

    Hubert, Olivier; Daniel, Laurent

    2011-01-01

    A main limitation of most models describing the effect of stress on the magnetic behavior is that they are restricted to uniaxial - tensile or compressive - stress. Nevertheless, stress is multiaxial in most of industrial applications. An idea to overcome the strong limitation of models is to define a fictive uniaxial stress, the equivalent stress, that would change the magnetic behavior in a similar manner than a multiaxial stress. A first definition of equivalent stress, called the deviatoric equivalent stress, is proposed. It is based on an equivalence in magneto-elastic energy. This formulation is first derived for isotropic materials under specific assumptions. An extension to orthotropic media under disoriented magneto-mechanical loading is made. A new equivalent stress expression, called generalized equivalent stress, is then proposed. It is based on an equivalence in magnetization. Inverse identification of equivalent stress is made possible thanks to a strong simplification of the description of the material seen as an assembly of elementary magnetic domains. It is shown that this second proposal is a generalization of the deviatoric expression. Equivalent stress proposals are compared to former proposals and validated using experimental results carried out on an iron-cobalt sheet submitted to biaxial mechanical loading. These results are compared to the predictions obtained thanks to the equivalent stress formulations. The generalized equivalent stress is shown to be a tool able to foresee the magnetic behavior of a large panel of materials submitted to multiaxial stress. - Research highlights: → Classical magneto-elastic models restricted to uniaxial stress. → Stress demonstrated multiaxial in most of industrial applications. → Proposals of deviatoric and generalized equivalent stresses - multidomain modeling. → Experimental validation using iron-cobalt sheet submitted to biaxial loading. → Generalization of former proposals and modeling of

  13. Stress- and Chemistry-Mediated Permeability Enhancement/Degradation in Stimulated Critically-Stressed Fractures

    Energy Technology Data Exchange (ETDEWEB)

    Derek Elsworth; Abraham S. Grader; Chris Marone; Phillip Halleck; Peter Rose; Igor Faoro; Joshua Taron; André Niemeijer; Hideaki Yasuhara

    2009-03-30

    This work has investigated the interactions between stress and chemistry in controlling the evolution of permeability in stimulated fractured reservoirs through an integrated program of experimentation and modeling. Flow-through experiments on natural and artificial fractures in Coso diorite have examined the evolution of permeability under paths of mean and deviatoric stresses, including the role of dissolution and precipitation. Models accommodating these behaviors have examined the importance of incorporating the complex couplings between stress and chemistry in examining the evolution of permeability in EGS reservoirs. This document reports the findings of experiment [1,2] and analysis [3,4], in four sequential chapters.

  14. Stress, strain, and temperature induced permeability changes in potential repository rocks

    International Nuclear Information System (INIS)

    Heard, H.C.; Duba, A.

    1977-01-01

    Work is in progress to assess the permeability characteristics of coarse-grained igneous rocks as affected by pressure, deviatoric stress, and temperature. In order to predict the long-term behavior of these rocks, both virgin and fractured, permeability and all principal strains resulting from an imposed deviatoric stress under various simulated lithostatic pressures are being measured. In addition, compressional as well as shear velocities and electrical conductivity are being evaluated along these principal directions. These simultaneous measurements are being made initially at 25 0 C on a 15 cm diameter by 30 cm long sample in a pressure apparatus controlled by a mini-computer. Correlation of these data with similar field observations should then allow simplified exploration for a suitable repository site as well as the prediction of the response of a mined cavity with both distance and time at this site. After emplacement of the waste canisters, the mechanical stability and hydrologic integrity of this mined repository will be directly influenced by the fracturing of the surrounding rock which results from local temperature differences and the thermal expansion of that rock. Temperatures (and, hence, these differences) in the vicinity of the repository are expected to be affected by the presence of pore fluids (single- or two-phase) in the rock, the heat capacity and the thermal conductivity of this system. In turn, these are all dependent upon lithostatic pressure, pore pressure, and stress. Thermal expansion (and fracturing) will also be affected by the lithostatic (and effective) pressure, the deviatoric stress field, and the initial anisotropy of the rock

  15. Calculation of Debye-Scherrer diffraction patterns from highly stressed polycrystalline materials

    Energy Technology Data Exchange (ETDEWEB)

    MacDonald, M. J., E-mail: macdonm@umich.edu [Applied Physics Program, University of Michigan, Ann Arbor, Michigan 48109 (United States); SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Vorberger, J. [Helmholtz Zentrum Dresden-Rossendorf, 01328 Dresden (Germany); Gamboa, E. J.; Glenzer, S. H.; Fletcher, L. B. [SLAC National Accelerator Laboratory, Menlo Park, California 94025 (United States); Drake, R. P. [Climate and Space Sciences and Engineering, Applied Physics, and Physics, University of Michigan, Ann Arbor, Michigan 48109 (United States)

    2016-06-07

    Calculations of Debye-Scherrer diffraction patterns from polycrystalline materials have typically been done in the limit of small deviatoric stresses. Although these methods are well suited for experiments conducted near hydrostatic conditions, more robust models are required to diagnose the large strain anisotropies present in dynamic compression experiments. A method to predict Debye-Scherrer diffraction patterns for arbitrary strains has been presented in the Voigt (iso-strain) limit [Higginbotham, J. Appl. Phys. 115, 174906 (2014)]. Here, we present a method to calculate Debye-Scherrer diffraction patterns from highly stressed polycrystalline samples in the Reuss (iso-stress) limit. This analysis uses elastic constants to calculate lattice strains for all initial crystallite orientations, enabling elastic anisotropy and sample texture effects to be modeled directly. The effects of probing geometry, deviatoric stresses, and sample texture are demonstrated and compared to Voigt limit predictions. An example of shock-compressed polycrystalline diamond is presented to illustrate how this model can be applied and demonstrates the importance of including material strength when interpreting diffraction in dynamic compression experiments.

  16. On the modelling of semi-insulating GaAs including surface tension and bulk stresses

    Energy Technology Data Exchange (ETDEWEB)

    Dreyer, W.; Duderstadt, F.

    2004-07-01

    Necessary heat treatment of single crystal semi-insulating Gallium Arsenide (GaAs), which is deployed in micro- and opto- electronic devices, generate undesirable liquid precipitates in the solid phase. The appearance of precipitates is influenced by surface tension at the liquid/solid interface and deviatoric stresses in the solid. The central quantity for the description of the various aspects of phase transitions is the chemical potential, which can be additively decomposed into a chemical and a mechanical part. In particular the calculation of the mechanical part of the chemical potential is of crucial importance. We determine the chemical potential in the framework of the St. Venant-Kirchhoff law which gives an appropriate stress/strain relation for many solids in the small strain regime. We establish criteria, which allow the correct replacement of the St. Venant-Kirchhoff law by the simpler Hooke law. The main objectives of this study are: (i) We develop a thermo-mechanical model that describes diffusion and interface motion, which both are strongly influenced by surface tension effects and deviatoric stresses. (ii) We give an overview and outlook on problems that can be posed and solved within the framework of the model. (iii) We calculate non-standard phase diagrams, i.e. those that take into account surface tension and non-deviatoric stresses, for GaAs above 786 C, and we compare the results with classical phase diagrams without these phenomena. (orig.)

  17. Implications for anomalous mantle pressure and dynamic topography from lithospheric stress patterns in the North Atlantic Realm

    DEFF Research Database (Denmark)

    Schiffer, Christian; Nielsen, Søren Bom

    2016-01-01

    With convergent plate boundaries at some distance, the sources of the lithospheric stress field of the North Atlantic Realm are mainly mantle tractions at the base of the lithosphere, lithospheric density structure and topography. Given this, we estimate horizontal deviatoric stresses using a wel...

  18. Global and Local Mechanical Responses for Necking of Rectangular Bars Using Updated and Total Lagrangian Finite Element Formulations

    Directory of Open Access Journals (Sweden)

    Claudio A. Careglio

    2016-01-01

    Full Text Available In simulations of forged and stamping processes using the finite element method, load displacement paths and three-dimensional stress and strains states should be well and reliably represented. The simple tension test is a suitable and economical tool to calibrate constitutive equations with finite strains and plasticity for those simulations. A complex three-dimensional stress and strain states are developed when this test is done on rectangular bars and the necking phenomenon appears. In this work, global and local numerical results of the mechanical response of rectangular bars subjected to simple tension test obtained from two different finite element formulations are compared and discussed. To this end, Updated and Total Lagrangian formulations are used in order to get the three-dimensional stress and strain states. Geometric changes together with strain and stress distributions at the cross section where necking occurs are assessed. In particular, a detailed analysis of the effective plastic strain, stress components in axial and transverse directions and pressure, and deviatoric stress components is presented. Specific numerical results are also validated with experimental measurements comparing, in turn, the performance of the two numerical approaches used in this study.

  19. Influence of shear and deviatoric stress on the evolution of permeability in fractured rock

    NARCIS (Netherlands)

    Faoro, Igor; Niemeijer, André; Marone, Chris; Elsworth, Derek

    The evolution of permeability in fractured rock as a function of effective normal stress, shear displacement, and damage remains a complex issue. In this contribution, we report on experiments in which rock surfaces were subject to direct shear under controlled pore pressure and true triaxial stress

  20. Modeling and Measurement of Stress and Strain Evolution in Cu Interconnects

    International Nuclear Information System (INIS)

    Besser, Paul R.; Zhai, Charlie Jun

    2004-01-01

    The damascene fabrication method and the introduction of low-K dielectrics present a host of reliability challenges to Cu interconnects and fundamentally change the mechanical stress state of Cu lines used as interconnects for integrated circuits. In order to capture the effect of individual process steps on the stress evolution in the BEoL (Back End of Line), a process-oriented finite element modeling (FEM) approach was developed. In this model, the complete stress history at any step of BEoL can be simulated as a dual damascene Cu structure is fabricated. The model was calibrated with both wafer-curvature blanket film measurements and X-Ray diffraction (XRD) measurement of metal line stress. The Cu line stress evolution was simulated during the process of multi-step processing for dual damascene Cu/TEOS and Cu/low-k structures. The in-plane stress of Cu lines is nearly independent of subsequent processes, while the out-of-plane stress increases considerably with the subsequent process steps. The modeling results will be compared with recent XRD measurements and extended generically to illustrate the relative influence of the dielectric (ILD) modulus (E) and coefficient of thermal expansion (CTE) on strain/stress in the Cu lines. It will be shown that the stress magnitude and state (hydrostatic, deviatoric) depend on ILD properties. The stress along the line length (longitudinal) is substrate-dominated, while the transverse and normal stresses vary with both CTE and modulus of the dielectric. The hydrostatic stress is primarily determined by ILD modulus and is nearly independent of the ILD CTE, while the Von Mises stress depends on both CTE and E of the ILD. The stress of the Cu line tends to be more deviatoric with spin-on low K ILDs, and more hydrostatic with oxide encapsulation

  1. Ionization and Corona Discharges from Stressed Rocks

    Science.gov (United States)

    Winnick, M. J.; Kulahci, I.; Cyr, G.; Tregloan-Reed, J.; Freund, F. T.

    2008-12-01

    Pre-earthquake signals have long been observed and documented, though they have not been adequately explained scientifically. These signals include air ionization, occasional flashes of light from the ground, radio frequency emissions, and effects on the ionosphere that occur hours or even days before large earthquakes. The theory that rocks function as p-type semiconductors when deviatoric stresses are applied offers a mechanism for this group of earthquake precursors. When an igneous or high-grade metamorphic rock is subjected to deviatoric stresses, peroxy bonds that exist in the rock's minerals as point defects dissociate, releasing positive hole charge carriers. The positive holes travel by phonon-assisted electron hopping from the stressed into and through the unstressed rock volume and build up a positive surface charge. At sufficiently large electric fields, especially along edges and sharp points of the rock, air molecules become field-ionized, loosing an electron to the rock surface and turning into airborne positive ions. This in turn can lead to corona discharges, which manifest themselves by flashes of light and radio frequency emissions. We applied concentrated stresses to one end of a block of gabbro, 30 x 15 x 10 cm3, inside a shielded Faraday cage and observed positive ion currents through an air gap about 25 cm from the place where the stresses were applied, punctuated by short bursts, accompanied by flashes of light and radio frequency emissions characteristic of a corona discharge. These observations may serve to explain a range of pre-earthquake signals, in particular changes in air conductivity, luminous phenomena, radio frequency noise, and ionospheric perturbations.

  2. On elastic waves in an thinly-layered laminated medium with stress couples under initial stress

    Directory of Open Access Journals (Sweden)

    P. Pal Roy

    1988-01-01

    Full Text Available The present work is concerned with a simple transformation rule in finding out the composite elastic coefficients of a thinly layered laminated medium whose bulk properties are strongly anisotropic with a microelastic bending rigidity. These elastic coefficients which were not known completely for a layered laminated structure, are obtained suitably in terms of initial stress components and Lame's constants λi, μi of initially isotropic solids. The explicit solutions of the dynamical equations for a prestressed thinly layered laminated medium under horizontal compression in a gravity field are derived. The results are discussed specifying the effects of hydrostatic, deviatoric and couple stresses upon the characteristic propagation velocities of shear and compression wave modes.

  3. New plastic plane stress model for concrete

    International Nuclear Information System (INIS)

    Winnicki, A.; Cichon, Cz.

    1993-01-01

    In the paper a description of concrete behaviour in the plane stress case is given on the basis of the modified bounding surface plasticity theory. Three independent plastic mechanisms have been introduced describing axiatoric and deviatoric plastic strains and their coupling. All the new analytical formulae for material functions being in agreement with experiments and loading/unloading criteria have been proposed. In addition, for the proper description of concrete behaviour in tension a new, separate function of bounding surface shrinkage has been introduced. (author)

  4. Effects of induced stress on seismic forward modelling and inversion

    Science.gov (United States)

    Tromp, Jeroen; Trampert, Jeannot

    2018-05-01

    We demonstrate how effects of induced stress may be incorporated in seismic modelling and inversion. Our approach is motivated by the accommodation of pre-stress in global seismology. Induced stress modifies both the equation of motion and the constitutive relationship. The theory predicts that induced pressure linearly affects the unstressed isotropic moduli with a slope determined by their adiabatic pressure derivatives. The induced deviatoric stress produces anisotropic compressional and shear wave speeds; the latter result in shear wave splitting. For forward modelling purposes, we determine the weak form of the equation of motion under induced stress. In the context of the inverse problem, we determine induced stress sensitivity kernels, which may be used for adjoint tomography. The theory is illustrated by considering 2-D propagation of SH waves and related Fréchet derivatives based on a spectral-element method.

  5. Deviatoric response of the aluminium alloy, 5083

    Science.gov (United States)

    Appleby-Thomas, Gareth; Hazell, Paul; Millett, Jeremy; Bourne, Neil

    2009-06-01

    Aluminium alloys such as 5083 are established light weight armour materials. As such, the shock response of these materials is of great importance. The shear strength of a material under shock loading provides an insight into its ballistic performance. In this investigation embedded manganin stress gauges have been employed to measure both the longitudinal and lateral components of stress during plate impact experiments over a range of impact stresses. In turn, these results were used to determine the shear strength and to investigate the time dependence of lateral stress behind the shock front to give an indication of material response.

  6. [Seasonal changes and response to stress of total flavonoids content of Farfugium japonicum].

    Science.gov (United States)

    Cui, Dalian; Ma, Yuxin

    2013-05-01

    To investigate the seasonal variation of total flavonoid content of Farfugium japonicum and its response to stress. The total flavonoids of Farfugium japonicum were determined by spectrophotometry in different seasons and under various stressful factors. The total flavonoid content in Farfugium japonicum leaves was the highest, followed by the petiole, and rhizomes (Pseasons (Pwater stress, the total flavonoid content in Farfugium japonicum leaves gradually increased, that in petiole first increased and then decreased,while that in rhizomes decreased (Pstress, the total flavonoid content in leaves, petioles and rhizomes of Farfugium japonicum showed a decreasing trend (Pseasons and that in different parts of the plant has different responses to ecological stressful factors.

  7. Experimental stress analysis of large plastic deformations in a hollow sphere deformed by impact against a concrete block

    Science.gov (United States)

    Morris, R. E.

    1973-01-01

    An experimental plastic strain measurement system is presented for use on the surface of high velocity impact test models. The system was used on a hollow sphere tested in impact against a reinforced concrete block. True strains, deviatoric stresses, and true stresses were calculated from experimental measurements. The maximum strain measured in the model was small compared to the true failure strain obtained from static tensile tests of model material. This fact suggests that a much greater impact velocity would be required to cause failure of the model shell structure.

  8. Decreased total antioxidant levels and increased oxidative stress in ...

    African Journals Online (AJOL)

    Background: Chronic hyperglycaemia in diabetes mellitus leads to increased lipid peroxidation in the body, followed by the development of chronic complications due to oxidative stress. Objective: The aim of this study was to compare total antioxidant (TAO) levels and oxidative stress in type 2 diabetes mellitus (T2DM) ...

  9. Deviatoric Response of AN Armour-Grade Aluminium Alloy

    Science.gov (United States)

    Appleby-Thomas, G. J.; Hazell, P. J.; Millett, J.; Bourne, N. K.

    2009-12-01

    Aluminium alloys such as 5083 H32 are established light-weight armour materials. As such, the shock response of these materials is of great importance. The shear strength of a material under shock loading provides an insight into its ballistic performance. In this investigation embedded manganin stress gauges have been employed to measure both the longitudinal and lateral components of stress during plate-impact experiments over a range of impact stresses. In turn, these results were used to determine the shear strength and to investigate the time dependence of lateral stress behind the shock front to give an indication of material response.

  10. Estimates of stress drop and crustal tectonic stress from the 27 February 2010 Maule, Chile, earthquake: Implications for fault strength

    Science.gov (United States)

    Luttrell, K.M.; Tong, X.; Sandwell, D.T.; Brooks, B.A.; Bevis, M.G.

    2011-01-01

    The great 27 February 2010 Mw 8.8 earthquake off the coast of southern Chile ruptured a ???600 km length of subduction zone. In this paper, we make two independent estimates of shear stress in the crust in the region of the Chile earthquake. First, we use a coseismic slip model constrained by geodetic observations from interferometric synthetic aperture radar (InSAR) and GPS to derive a spatially variable estimate of the change in static shear stress along the ruptured fault. Second, we use a static force balance model to constrain the crustal shear stress required to simultaneously support observed fore-arc topography and the stress orientation indicated by the earthquake focal mechanism. This includes the derivation of a semianalytic solution for the stress field exerted by surface and Moho topography loading the crust. We find that the deviatoric stress exerted by topography is minimized in the limit when the crust is considered an incompressible elastic solid, with a Poisson ratio of 0.5, and is independent of Young's modulus. This places a strict lower bound on the critical stress state maintained by the crust supporting plastically deformed accretionary wedge topography. We estimate the coseismic shear stress change from the Maule event ranged from-6 MPa (stress increase) to 17 MPa (stress drop), with a maximum depth-averaged crustal shear-stress drop of 4 MPa. We separately estimate that the plate-driving forces acting in the region, regardless of their exact mechanism, must contribute at least 27 MPa trench-perpendicular compression and 15 MPa trench-parallel compression. This corresponds to a depth-averaged shear stress of at least 7 MPa. The comparable magnitude of these two independent shear stress estimates is consistent with the interpretation that the section of the megathrust fault ruptured in the Maule earthquake is weak, with the seismic cycle relieving much of the total sustained shear stress in the crust. Copyright 2011 by the American

  11. Thin Sheet Modeling for the Seismogenic Crust of Western North America: How Strong is the top Slice of "Sandwich Bread" Above the "Jelly"?

    Science.gov (United States)

    Klein, E. C.; Holt, W. E.; Flesch, L. M.; Haines, A. J.

    2006-12-01

    The "jelly sandwich" and "crème brûlée" models divides continental lithosphere into distinct rheological layers. Dynamic models from thin sheet approximations provide estimates of the total strength of the lithosphere, but only to a thickness governed by the degree of mechanical coupling between rheological layers. If either the "jelly sandwich" or the "crème brûlée" model of the lithosphere is appropriate for the diffuse plate boundary zone setting of western North America, we expect a sharp contrast or decoupling between the strong upper crust ("bread") layer overlying the weak lower crustal ("jelly") layer. We examine the strength of the upper crust with and without strength contribution from the lower crust using thin sheet modeling methodologies. We use seismically defined densities to constrain vertical integrals of vertical stress (GPE) within the crust. Neglecting stresses due to flexure as well as shear stresses at the base of the crustal layer, lateral differences in GPE within the layer, are balanced solely by gradients in horizontal deviatoric stress [Flesch et al., 2001, 2006]. We solve the force-balance equations for the minimum deviatoric stress field associated with gradients of GPE. This deviatoric stress field calibrates the magnitude of deviatoric stresses within the seismogenic layer. We then solve for stress field boundary conditions associated with the stress field contributions from sources outside the modeled region that together with the minimum solution from GPE differences provide a best match with stress field indicators within western North America. In order to infer appropriate stress field indicators we develop a long-term kinematic strain rate and velocity field model. Where we use this strain rate field we assume that the relationship between deviatoric stress directions and kinematic strain rate directions is isotropic. In our calculations the seismogenic layer extends from the surface to either a uniform depth below sea

  12. Preliminary investigation of the structural influence of entry-entry intersections and inhomogeneous initial-stress fields on repository disposal rooms

    International Nuclear Information System (INIS)

    Loken, M.C.

    1983-07-01

    The structural influence of entry-entry intersections and inhomogeneous initial stress fields on a repository configuration has been investigated. The out-of-plane stress increases rapidly into the pillar from the rib of the connecting corridor to the plane strain value within one pillar width of the intersection, indicating that a two-dimensional analysis is valid over a major portion of the disposal room and pillar. Inhomogeneous initial stress fields do not significantly alter the trends of the resulting post-excavation stress fields. However, the magnitude of the vertical stress and the effective stress is slightly greater near the corner at the intersection. Further nonlinear analyses are required to assess the stability of the pillar at the intersection because of the high deviatoric stresses occurring in that region. 6 references

  13. Use of pressurized eccentric tubes to study the effect of hydrostatic stress on swelling

    International Nuclear Information System (INIS)

    Wolfer, W.G.; Reiley, T.C.

    1977-05-01

    A technique for measuring the effect of hydrostatic stress on radiation-induced swelling is presented. This technique is based on the nonuniform hydrostatic stress that arises when an eccentric tube (a tube with inner and outer surfaces having dissimilar centers of revolution) is internally pressurized. The elastic analyses of the thin- and thick-walled eccentric tube are given. The elastic stress state is allowed to relax plastically, based on a constitutive law for deformation during neutron irradiation. In this case, the constitutive law contains a linearly stress-dependent deviatoric strain rate and a dilatation rate that is linearly dependent on hydrostatic stress. Emphasis is placed on the specimen design and experimental procedure for in-reactor experiments in which the coefficient relating hydrostatic stress and swelling is sought. It is shown that, for the 316L stainless steel specimens placed in EBR-II, we may expect that any appreciable effect of hydrostatic stress on swelling will be observable through changes in specimen curvature

  14. Mitigation method of thermal transient stress by thermalhydraulic-structure total analysis

    International Nuclear Information System (INIS)

    Kasahara, Naoto; Jinbo, Masakazu; Hosogai, Hiromi

    2003-01-01

    This study proposes a rational evaluation and mitigation method of thermal transient loads in fast reactor components by utilizing relationships among plant system parameters and stresses induced by thermal transients of plants. A thermalhydraulic-structure total analysis procedure helps us to grasp relationship among system parameters and thermal stresses. Furthermore, it enables mitigation of thermal transient loads by adjusting system parameters. In order to overcome huge computations, a thermalhydraulic-structure total analysis code and the Design of Experiments methodology are utilized. The efficiency of the proposed mitigation method is validated through thermal stress evaluation of an intermediate heat exchanger in Japanese demonstration fast reactor. (author)

  15. Coping strategies related to total stress score among post graduate medical students and residents

    Directory of Open Access Journals (Sweden)

    R. Irawati Ismail

    2013-05-01

    Full Text Available AbstrakLatar belakang:Beberapa strategi penanganan yang dapat mengurangi tingkat stres. Tujuan penelitian ini untuk mengidentifikasi beberapa strategi yang dominan terhadap tingkat skor stres total.Metode:Pada penelitian potong lintang dengan sampel purposif mahasiswa kedokteran pasca sarjana Fakultas Kedokteran Universitas Indonesia pada bulan April-Juli 2011. Kuesioner yang digunakan ialah kuesioner strategi mengurangi stres dan self reporting questionnaire WHO (SRQ-20. Regresi liniar digunakan Untuk mengidentifikasi faktor dominan terhadap tingkat stres dipergunakan regresi linear.Hasil: Subjek terdiri dari 272 orang, usia 23-44 tahun. Empat hal menurunkan skor stres total (menerima realitas, berbicara dengan seseorang yang dapat melakukan sesuatu, meminta bantuan Allah, dan menertawakan situasi yang bermasalah. Sebaiknya tiga faktor meningkatkan skor stres total (menyelesaikan langkah demi langkah pada suatu waktu, berbicara dengan seseorang untuk mengetahui lebih lanjut tentang situasi, dan mengakui tidak bisa menangani pemecahan situasi. Satu poin menerima realitas situasi mengurangi 0,493 poin skor total stress [koefisien regresi (β = -0,493, P = 0,002]. Sementara satu poin mencari pertolongan Allah akan mengurangi 0,307 poin skor stres total (β = -0,307, P = 0,056. Namun, satu poin melakukan satu langkah pada suatu waktu akan meningkatkan 0,54 poin skor stres total (β = 0,540, P = 0,005.Kesimpulan: Menerima realitas, berbicara dengan seseorang yang dapat melakukan sesuatu, meminta bantuan Allah, dan menertawakan situasi akan menurunkan tingkat stres. Sebaiknya, menyelesaikan langkah demi langkah pada suatu waktu, berbicara dengan seseorang untuk mengetahui lebih lanjut tentang situasi, dan mengakui tidak bisa menangani memecahkan situasi, meningkatkan skor stres total.Kata kunci:strategi pengendalan stres, meminta pertolongan AlllahAbstractBackground:Several coping strategies may minimize stress levels. This study aimed to identify

  16. Decreased total antioxidant levels and increased oxidative stress in ...

    African Journals Online (AJOL)

    21–25 ... Decreased total antioxidant levels and increased oxidative stress in South ... antioxidant-rich diet and lifestyle changes in T2DM patients would help to avert the .... glycation of proteins and the formation of advanced glycosylation.

  17. Non-hydrostatic behavior of KBr as a pressure medium in diamond anvil cells up to 5.63 GPa

    International Nuclear Information System (INIS)

    Zhao, Jing; Ross, Nancy L

    2015-01-01

    Non-hydrostatic stresses of KBr acting as a pressure–transmitting medium have been investigated by examining their effect on a single crystal of quartz in a diamond anvil cell (DAC). The lattice strains or distortions were measured by single-crystal x-ray diffraction methods, and the non-hydrostatic deviatoric stresses for KBr were determined up to 5.63(2) GPa. The experimental results show that differences between axial stress components in the direction normal to the DAC culet face and the radial stress components in directions parallel to the DAC culet face are about 0.063(24) GPa at pressures below 2.14 GPa, and the pressure-transmitting medium can therefore be considered as quasi-hydrostatic up to this pressure. However above 2.14 GPa, after the phase transition pressure of KBr during which it converts from the B1 phase to the B2 phase, the deviatoric stresses constantly increase with increasing pressure. At the maximum pressure of this study, 5.63(2) GPa, the difference between axial stress and radial stress components reaches 0.93(9) GPa. Different variations in the non-hydrostatic deviatoric stresses were observed during both compression and decompression of the DAC, and are mainly ascribed to the phase-transition-induced volume change of KBr. (paper)

  18. Applicability of initial stress measurement methods to Horonobe Siliceous rocks and initial stress state around Horonobe Underground Research Laboratory

    International Nuclear Information System (INIS)

    Sanada, Hiroyuki; Niunoya, Sumio; Matsui, Hiroya; Fujii, Yoshiaki

    2009-01-01

    Understanding initial stress condition in deep underground is important for such construction as rock cavern for geological disposal of HLW and underground power plant. Neogene sedimentary rock is widely distributed in Japan. There are only a few studies of initial stress measurement in Neogene sedimentary rock mass in Japan due to difficulty of measurement. Evaluation of initial stress condition around Horonobe Underground Research Laboratory Project was carried out in order to understand initial stress condition and applicability of AE, DSCA and hydraulic fracturing (HF) methods to Neogene sedimentary rock. Initial stress values obtained from AE method is smaller than overburden pressure due to time dependency of Kaizer effect. It would be difficult to use AE method as initial stress measurement method for Horonobe Siliceous rocks. Principal stress values by DSCA are similar to those by HF tests. Directions of maximum horizontal principal stresses are approximately in E-W and corresponded to HF results. In HF, rod type and wire-line type systems were compared. Workability of rod type was much better than wire-line type. However, re-opening pressure were not able to be precisely measured in case of rod type system due to the large compliance of the packers and rods. Horizontal maximum and minimum principal stresses increase linearly in HF results. Deviatoric stress is acting at shallow depth. Initial stress condition approaches hydrostatic condition with depth. Direction of maximum horizontal principal stress was in E-W direction which was similar to tectonic movement around Horonobe URL by triangular surveying. (author)

  19. Bound-Preserving Reconstruction of Tensor Quantities for Remap in ALE Fluid Dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Klima, Matej [Czech Technical Univ. in Prague, Praha (Czech Republic); Kucharik, MIlan [Czech Technical Univ. in Prague, Praha (Czech Republic); Shashkov, Mikhail Jurievich [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Velechovsky, Jan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-01-06

    We analyze several new and existing approaches for limiting tensor quantities in the context of deviatoric stress remapping in an ALE numerical simulation of elastic flow. Remapping and limiting of the tensor component-by-component is shown to violate radial symmetry of derived variables such as elastic energy or force. Therefore, we have extended the symmetry-preserving Vector Image Polygon algorithm, originally designed for limiting vector variables. This limiter constrains the vector (in our case a vector of independent tensor components) within the convex hull formed by the vectors from surrounding cells – an equivalent of the discrete maximum principle in scalar variables. We compare this method with a limiter designed specifically for deviatoric stress limiting which aims to constrain the J2 invariant that is proportional to the specific elastic energy and scale the tensor accordingly. We also propose a method which involves remapping and limiting the J2 invariant independently using known scalar techniques. The deviatoric stress tensor is then scaled to match this remapped invariant, which guarantees conservation in terms of elastic energy.

  20. Experimental determination of the stress/strain situation in a sheared tunnel model with canister

    International Nuclear Information System (INIS)

    Pusch, R.

    1978-03-01

    A previous report concerned a technical matter which could be of great importance as regards the mechanical strength of canisters embedded in a bentonite/quartz buffer mass, i.e. the effect of a differential movement triggered by a critical deviatoric stress condition. Even if this is extremely unlikeley to occur it was considered to be of importance to verify the theoretical expressions for the maximum bending moment and maximum shear force. A special reason was to test the hypothesis that the contact pressure would soon reach a high value and then stay fairly constant when the displacement increased. The theoretical approach requires that the stress/strain properties of the fill are thoroghly investigated and described in therms of a mathematical model. Experience shows that this may be a tedions and difficult task. (L.E.)

  1. Stress path dependent hydromechanical behaviour of heterogeneous carbonate rock

    Directory of Open Access Journals (Sweden)

    Dimanov A.

    2010-06-01

    Full Text Available The influence of stress paths, representative of reservoir conditions, on the hydromechanical behavior of a moderately heterogeneous carbonate has been investigated. Multiscale structural heterogeneities, common for instance in carbonate rocks, can strongly alter the mechanical response and significantly influence the evolution of flow properties with stress. Using a triaxial cell, the permeability evolutions during compression and the effects of brittle (fracture and plastic (pore collapse deformations at yield, were measured. A strong scattering was observed on the mechanical response both in term of compressibility and failure threshold. Using the porosity scaling predicted by an adapted effective medium theory (based on crack growth under Hertzian contact, we have rescaled the critical pressures by the normalized porosity deviation. This procedure reduces efficiently the scattering, revealing in the framework of proportional stress path loading, a linear relation between the critical pressures and the stress path parameter through all the deformation regimes. It leads to a new formulation for the critical state envelope in the 'mean stress, deviatoric stress' diagram. The attractive feature of this new yield envelope formulation relies on the fact that only the two most common different mechanical tests 'Uniaxial Compression' and 'Hydrostatic Compression', are needed to define entirely the yield envelope. Volumic strains and normalized permeabilities are finally mapped in the stresses diagram and correlated.

  2. Influence of oxidative stress on the development of collateral circulation in total coronary occlusions.

    Science.gov (United States)

    Demirbag, Recep; Gur, Mustafa; Yilmaz, Remzi; Kunt, Alper Sami; Erel, Ozcan; Andac, M Halit

    2007-03-02

    The purpose of this study was to investigate whether the levels of total antioxidant capacity (TAC), total peroxide and oxidative stress index (OSI) are associated with the development of collaterals in total coronary occlusions. Our study group contained 176 consecutive men patients with single-vessel TCO, 94 of whom had poorly developed coronary collateral, while 82 had well-developed coronary collateral. TAC and total peroxide concentration were measured of plasma. The ratio of TAC to total peroxide was accepted as an indicator of oxidative stress. The values of total peroxide and OSI in the Group I were significantly lower than that in Group II (ptotal peroxide and OSI levels (ptotal peroxide and OSI were independent predictors of collaterals score (p=0.006 and ptotal coronary occlusion patients.

  3. High order curvilinear finite elements for elastic–plastic Lagrangian dynamics

    International Nuclear Information System (INIS)

    Dobrev, Veselin A.; Kolev, Tzanio V.; Rieben, Robert N.

    2014-01-01

    This paper presents a high-order finite element method for calculating elastic–plastic flow on moving curvilinear meshes and is an extension of our general high-order curvilinear finite element approach for solving the Euler equations of gas dynamics in a Lagrangian frame [1,2]. In order to handle transition to plastic flow, we formulate the stress–strain relation in rate (or incremental) form and augment our semi-discrete equations for Lagrangian hydrodynamics with an additional evolution equation for the deviatoric stress which is valid for arbitrary order spatial discretizations of the kinematic and thermodynamic variables. The semi-discrete equation for the deviatoric stress rate is developed for 2D planar, 2D axisymmetric and full 3D geometries. For each case, the strain rate is approximated via a collocation method at zone quadrature points while the deviatoric stress is approximated using an L 2 projection onto the thermodynamic basis. We apply high order, energy conserving, explicit time stepping methods to the semi-discrete equations to develop the fully discrete method. We conclude with numerical results from an extensive series of verification tests that demonstrate several practical advantages of using high-order finite elements for elastic–plastic flow

  4. High-pressure crystal structure of elastically isotropic CaTiO3 perovskite under hydrostatic and non-hydrostatic conditions.

    Science.gov (United States)

    Zhao, Jing; Ross, Nancy L; Wang, Di; Angel, Ross J

    2011-11-16

    The structural evolution of orthorhombic CaTiO3 perovskite has been studied using high-pressure single-crystal x-ray diffraction under hydrostatic conditions up to 8.1 GPa and under a non-hydrostatic stress field formed in a diamond anvil cell (DAC) up to 4.7 GPa. Under hydrostatic conditions, the TiO6 octahedra become more tilted and distorted with increasing pressure, similar to other 2:4 perovskites. Under non-hydrostatic conditions, the experiments do not show any apparent difference in the internal structural variation from hydrostatic conditions and no additional tilts and distortions in the TiO6 octahedra are observed, even though the lattice itself becomes distorted due to the non-hydrostatic stress. The similarity between the hydrostatic and non-hydrostatic cases can be ascribed to the fact that CaTiO3 perovskite is nearly elastically isotropic and, as a consequence, its deviatoric unit-cell volume strain produced by the non-hydrostatic stress is very small; in other words, the additional octahedral tilts relevant to the extra unit-cell volume associated with the deviatoric unit-cell volume strain may be totally neglected. This study further addresses the role that three factors--the elastic properties, the crystal orientation and the pressure medium--have on the structural evolution of an orthorhombic perovskite loaded in a DAC under non-hydrostatic conditions. The influence of these factors can be clearly visualized by plotting the three-dimensional distribution of the deviatoric unit-cell volume strain in relation to the cylindrical axis of the DAC and indicates that, if the elasticity of a perovskite is nearly isotropic as it is for CaTiO3, the other two factors become relatively insignificant.

  5. High-pressure crystal structure of elastically isotropic CaTiO3 perovskite under hydrostatic and non-hydrostatic conditions

    International Nuclear Information System (INIS)

    Zhao Jing; Ross, Nancy L; Wang, Di; Angel, Ross J

    2011-01-01

    The structural evolution of orthorhombic CaTiO 3 perovskite has been studied using high-pressure single-crystal x-ray diffraction under hydrostatic conditions up to 8.1 GPa and under a non-hydrostatic stress field formed in a diamond anvil cell (DAC) up to 4.7 GPa. Under hydrostatic conditions, the TiO 6 octahedra become more tilted and distorted with increasing pressure, similar to other 2:4 perovskites. Under non-hydrostatic conditions, the experiments do not show any apparent difference in the internal structural variation from hydrostatic conditions and no additional tilts and distortions in the TiO 6 octahedra are observed, even though the lattice itself becomes distorted due to the non-hydrostatic stress. The similarity between the hydrostatic and non-hydrostatic cases can be ascribed to the fact that CaTiO 3 perovskite is nearly elastically isotropic and, as a consequence, its deviatoric unit-cell volume strain produced by the non-hydrostatic stress is very small; in other words, the additional octahedral tilts relevant to the extra unit-cell volume associated with the deviatoric unit-cell volume strain may be totally neglected. This study further addresses the role that three factors-the elastic properties, the crystal orientation and the pressure medium-have on the structural evolution of an orthorhombic perovskite loaded in a DAC under non-hydrostatic conditions. The influence of these factors can be clearly visualized by plotting the three-dimensional distribution of the deviatoric unit-cell volume strain in relation to the cylindrical axis of the DAC and indicates that, if the elasticity of a perovskite is nearly isotropic as it is for CaTiO 3 , the other two factors become relatively insignificant. (paper)

  6. Assessment of an improved multiaxial strength theory based on creep-rupture data for Inconel 600

    International Nuclear Information System (INIS)

    Huddleston, R.L.

    1993-01-01

    A new multiaxial strength theory incorporating three independent stress parameters was developed and reported by the author in 1984. It was formally incorporated into ASME Code Case N47-29 in 1990. The new theory provided significantly more accurate stress-rupture life predictions than obtained using the classical theories of von Mises, Tresca, and Rankins (maximum principal stress), for Types 304 and 316 stainless steel tested at 593 and 600 degrees C respectively under different biaxial stress states. Additional results for Inconel 600 specimens tested at 816 degrees C under tension-tension and tension-compression stress states are presented in this paper and show a factor of approximately 2.4 reduction in the scatter of predicted versus observed lives as compared to the classical theories of von Mises and Tresca and a factor of about 5 as compared to the Rankins theory. A key feature of the theory, which incorporates the maximum deviatoric stress, the first invariant of the stress tensor, and the second invariant of the deviatoric stress tensor, is its ability to distinguish between life under tensile versus compressive stress states

  7. Experimental investigation of creep behavior of clastic rock in Xiangjiaba Hydropower Project

    Directory of Open Access Journals (Sweden)

    Yu Zhang

    2015-01-01

    Full Text Available There are many fracture zones crossing the dam foundation of the Xiangjiaba Hydropower Project in southwestern China. Clastic rock is the main media of the fracture zone and has poor physical and mechanical properties. In order to investigate the creep behavior of clastic rock, triaxial creep tests were conducted using a rock servo-controlling rheological testing machine. The results show that the creep behavior of clastic rock is significant at a high level of deviatoric stress, and less time-dependent deformation occurs at high confining pressure. Based on the creep test results, the relationship between axial strain and time under different confining pressures was investigated, and the relationship between axial strain rate and deviatoric stress was also discussed. The strain rate increases rapidly, and the rock sample fails eventually under high deviatoric stress. Moreover, the creep failure mechanism under different confining pressures was analyzed. The main failure mechanism of clastic rock is plastic shear, accompanied by a significant compression and ductile dilatancy. On the other hand, with the determined parameters, the Burgers creep model was used to fit the creep curves. The results indicate that the Burgers model can exactly describe the creep behavior of clastic rock in the Xiangjiaba Hydropower Project.

  8. A computational model of blast loading on the human eye.

    Science.gov (United States)

    Bhardwaj, Rajneesh; Ziegler, Kimberly; Seo, Jung Hee; Ramesh, K T; Nguyen, Thao D

    2014-01-01

    Ocular injuries from blast have increased in recent wars, but the injury mechanism associated with the primary blast wave is unknown. We employ a three-dimensional fluid-structure interaction computational model to understand the stresses and deformations incurred by the globe due to blast overpressure. Our numerical results demonstrate that the blast wave reflections off the facial features around the eye increase the pressure loading on and around the eye. The blast wave produces asymmetric loading on the eye, which causes globe distortion. The deformation response of the globe under blast loading was evaluated, and regions of high stresses and strains inside the globe were identified. Our numerical results show that the blast loading results in globe distortion and large deviatoric stresses in the sclera. These large deviatoric stresses may be indicator for the risk of interfacial failure between the tissues of the sclera and the orbit.

  9. Numerical and experimental investigations on the time dependent behavior of a salt dome with a high-level waste repository

    International Nuclear Information System (INIS)

    Prij, J.; Vons, L.H.

    1984-01-01

    Results are presented of in-situ measurements, performed in a 300 m deep dry-drilled borehole, in the ASSE-mine. Convergence measurements at ambient as well as elevated temperatures and pressure measurements at elevated temperatures are discussed. Creep equations derived from these experiments are used for the numerical analysis of the time dependent behavior of a salt dome with a HLW repository. The analyses show that the total stresses in the salt remain compressive with deviatoric components smaller than 3 MPa. 9 references, 6 figures, 1 table

  10. Diamond-anvil cell for radial x-ray diffraction

    International Nuclear Information System (INIS)

    Chesnut, G N; Schiferl, D; Streetman, B D; Anderson, W W

    2006-01-01

    We have designed a new diamond-anvil cell capable of radial x-ray diffraction to pressures of a few hundred GPa. The diffraction geometry allows access to multiple angles of Ψ, which is the angle between each reciprocal lattice vector g(hkl) and the compression axis of the cell. At the 'magic angle', Ψ∼54.7 0 , the effects of deviatoric stresses on the interplanar spacings, d(hkl), are significantly reduced. Because the systematic errors, which are different for each d(hkl), are significantly reduced, the crystal structures and the derived equations of state can be determined reliably. At other values of Ψ, the effects of deviatoric stresses on the diffraction pattern could eventually be used to determine elastic constants

  11. Ratchetting strain prediction

    International Nuclear Information System (INIS)

    Noban, Mohammad; Jahed, Hamid

    2007-01-01

    A time-efficient method for predicting ratchetting strain is proposed. The ratchetting strain at any cycle is determined by finding the ratchetting rate at only a few cycles. This determination is done by first defining the trajectory of the origin of stress in the deviatoric stress space and then incorporating this moving origin into a cyclic plasticity model. It is shown that at the beginning of the loading, the starting point of this trajectory coincides with the initial stress origin and approaches the mean stress, displaying a power-law relationship with the number of loading cycles. The method of obtaining this trajectory from a standard uniaxial asymmetric cyclic loading is presented. Ratchetting rates are calculated with the help of this trajectory and through the use of a constitutive cyclic plasticity model which incorporates deviatoric stresses and back stresses that are measured with respect to this moving frame. The proposed model is used to predict the ratchetting strain of two types of steels under single- and multi-step loadings. Results obtained agree well with the available experimental measurements

  12. Contact stresses, pressure and area in a fixed-bearing total ankle replacement: a finite element analysis.

    Science.gov (United States)

    Martinelli, Nicolo; Baretta, Silvia; Pagano, Jenny; Bianchi, Alberto; Villa, Tomaso; Casaroli, Gloria; Galbusera, Fabio

    2017-11-25

    Mobile-bearing ankle implants with good clinical results continued to increase the popularity of total ankle arthroplasty to address endstage ankle osteoarthritis preserving joint movement. Alternative solutions used fixed-bearing designs, which increase stability and reduce the risk of bearing dislocation, but with a theoretical increase of contact stresses leading to a higher polyethylene wear. The purpose of this study was to investigate the contact stresses, pressure and area in the polyethylene component of a new total ankle replacement with a fixed-bearing design, using 3D finite element analysis. A three-dimensional finite element model of the Zimmer Trabecular Metal Total Ankle was developed and assembled based on computed tomography images. Three different sizes of the polyethylene insert were modeled, and a finite element analysis was conducted to investigate the contact pressure, the von Mises stresses and the contact area of the polyethylene component during the stance phase of the gait cycle. The peak value of pressure was found in the anterior region of the articulating surface, where it reached 19.8 MPa at 40% of the gait cycle. The average contact pressure during the stance phase was 6.9 MPa. The maximum von Mises stress of 14.1 MPa was reached at 40% of the gait cycle in the anterior section. In the central section, the maximum von Mises stress of 10.8 MPa was reached at 37% of the gait cycle, whereas in the posterior section the maximum stress of 5.4 MPa was reached at the end of the stance phase. The new fixed-bearing total ankle replacement showed a safe mechanical behavior and many clinical advantages. However, advanced models to quantitatively estimate the wear are need. To the light of the clinical advantages, we conclude that the presented prosthesis is a good alternative to the other products present in the market.

  13. Combined nitrogen limitation and cadmium stress stimulate total carbohydrates, lipids, protein and amino acid accumulation in Chlorella vulgaris (Trebouxiophyceae)

    Energy Technology Data Exchange (ETDEWEB)

    Chia, Mathias Ahii, E-mail: chia28us@yahoo.com [Department of Botany, Federal University of São Carlos, Rodovia Washington Luis km 235, São Carlos, SP Cep 13565905 (Brazil); Lombardi, Ana Teresa [Department of Botany, Federal University of São Carlos, Rodovia Washington Luis km 235, São Carlos, SP Cep 13565905 (Brazil); Graça Gama Melão, Maria da [Department of Hydrobiology, Federal University of São Carlos, Rodovia Washington Luis km 235, São Carlos, SP Cep 13565905 (Brazil); Parrish, Christopher C. [Department of Ocean Sciences, Memorial University of Newfoundland, St. John’s, Newfoundland A1C 5S7 (Canada)

    2015-03-15

    Highlights: • Chlorella vulgaris was exposed to Cd under varying N concentrations. • Growth rate and cell density decreased with increasing Cd stress and N limitation. • Dry weight, chlorophyll a, total lipid, carbohydrate and protein were accumulated. • Amino acids like proline and glutamine were accumulated under N and Cd stress. • Changes in amino acid composition are sensitive biomarkers for Cd and N stress. - Abstract: Metals have interactive effects on the uptake and metabolism of nutrients in microalgae. However, the effect of trace metal toxicity on amino acid composition of Chlorella vulgaris as a function of varying nitrogen concentrations is not known. In this research, C. vulgaris was used to investigate the influence of cadmium (10{sup −7} and 2.0 × 10{sup −8} mol L{sup −1} Cd) under varying nitrogen (2.9 × 10{sup −6}, 1.1 × 10{sup −5} and 1.1 × 10{sup −3} mol L{sup −1} N) concentrations on its growth rate, biomass and biochemical composition. Total carbohydrates, total proteins, total lipids, as well as individual amino acid proportions were determined. The combination of Cd stress and N limitation significantly inhibited growth rate and cell density of C. vulgaris. However, increasing N limitation and Cd stress stimulated higher dry weight and chlorophyll a production per cell. Furthermore, biomolecules like total proteins, carbohydrates and lipids increased with increasing N limitation and Cd stress. Ketogenic and glucogenic amino acids were accumulated under the stress conditions investigated in the present study. Amino acids involved in metal chelation like proline, histidine and glutamine were significantly increased after exposure to combined Cd stress and N limitation. We conclude that N limitation and Cd stress affects the physiology of C. vulgaris by not only decreasing its growth but also stimulating biomolecule production.

  14. Comparison of stress and total energy methods for calculation of elastic properties of semiconductors.

    Science.gov (United States)

    Caro, M A; Schulz, S; O'Reilly, E P

    2013-01-16

    We explore the calculation of the elastic properties of zinc-blende and wurtzite semiconductors using two different approaches: one based on stress and the other on total energy as a function of strain. The calculations are carried out within the framework of density functional theory in the local density approximation, with the plane wave-based package VASP. We use AlN as a test system, with some results also shown for selected other materials (C, Si, GaAs and GaN). Differences are found in convergence rate between the two methods, especially in low symmetry cases, where there is a much slower convergence for total energy calculations with respect to the number of plane waves and k points used. The stress method is observed to be more robust than the total energy method with respect to the residual error in the elastic constants calculated for different strain branches in the systems studied.

  15. Total antioxidant capacity, total oxidant status and oxidative stress index in the men exposed to 1.5 T static magnetic field.

    Science.gov (United States)

    Sirmatel, O; Sert, C; Sirmatel, F; Selek, S; Yokus, B

    2007-06-01

    The aim of this study was to investigate the effects of a high-strength magnetic field produced by a magnetic resonance imaging (MRI) apparatus on oxidative stress. The effects of a 1.5 T static magnetic field on the total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) in male subjects were investigated. In this study, 33 male volunteers were exposed to a 1.5 T static magnetic field for a short time and the TAC, TOS and OSI of each subject were determined. Magnetic field exposure was provided using a magnetic resonance apparatus; radiofrequency was not applied. Blood samples were taken from subjects and TAC, TOS and OSI values were measured using the methods of Erel. TAC showed a significant increase in post-exposures compared to pre-exposures to the magnetic field (p < 0.05). OSI and TOS showed a significant decrease in post-exposures compared to pre-exposures to a 1.5 T magnetic field (for each of two, p < 0.01). The 1.5 T static magnetic field used in the MRI apparatus did not yield a negative effect; on the contrary, it produced the positive effect of decreasing oxidative stress in men following short-term exposure.

  16. Induced groundwater flux by increases in the aquifer's total stress.

    Science.gov (United States)

    Chang, Ching-Min; Yeh, Hund-Der

    2015-01-01

    Fluid-filled granular soils experience changes in total stress because of earth and oceanic tides, earthquakes, erosion, sedimentation, and changes in atmospheric pressure. The pore volume may deform in response to the changes in stress and this may lead to changes in pore fluid pressure. The transient fluid flow can therefore be induced by the gradient in excess pressure in a fluid-saturated porous medium. This work demonstrates the use of stochastic methodology in prediction of induced one-dimensional field-scale groundwater flow through a heterogeneous aquifer. A closed-form of mean groundwater flux is developed to quantify the induced field-scale mean behavior of groundwater flow and analyze the impacts of the spatial correlation length scale of log hydraulic conductivity and the pore compressibility. The findings provided here could be useful for the rational planning and management of groundwater resources in aquifers that contain lenses with large vertical aquifer matrix compressibility values. © 2014, National Ground Water Association.

  17. Stress-reaction during hypokinesia and its effect on total resistance of the animal body

    International Nuclear Information System (INIS)

    Chernov, I.P.

    1980-01-01

    In the experiments on rats, shown has been that three-phase stress-reaction develops during the hypokinetic syndrome formation. This reaction is confirmed by specific changes of general state of the organism, body mass and by the activity of hypothalamic-hypophysial-adrenal system evaluated by oscillations of relative mass of pituitary body and adrenal glands and by karyometry of neuron of the hypothalamus arcuate nuclear and cells of zona fasciculata of adrenal glands. The hypokinetic stress affects the total resistance of the body, its sensitivity to gamma-irradiation in the dose of 800 rad. On the definite stage of development the hypokinetic stress forms the state of heightened ''cross'' stability

  18. Oxidative stress and total antioxidant status in term newborns and their mothers

    Directory of Open Access Journals (Sweden)

    Maria Wilinska

    2015-12-01

    Full Text Available The peripartum period and delivery are considered critical for maintaining a balance between the production of free oxygen radicals and functional incompetence of the antioxidant system of a foetus and a neonate. [b]Objective.[/b] The aim of the study was to evaluate the oxidoreductive state of mothers and their newborns immediately after delivery and in the first few days after birth. [b]Method.[/b] Eighty-five mothers and their healthy, term newborns were included into the prospective study. Total antioxidant capacity (TAC and thiobarbituric acid reactive substances (TBARS in maternal placenta and milk, as well as blood and urine of the neonates on the first and third day after birth, were examined. [b]Results.[/b] Elevated levels of TBARS were found in maternal placenta and neonatal blood on the third day after birth, but low concentrations were observed in maternal milk. On the contrary, total antioxidant status (TAS showed a declining tendency in neonatal blood and an increasing tendency in breast milk. Markers of oxidative stress and antioxidant capacity were independent of the mode of delivery. [b]Conclusions.[/b] Values of oxidative stress markers in mothers and newborns immediately after birth were elevated and increased further during the first few days of neonatal life. Breast milk was the only nutritional substance with high antioxidant activity. At the same time, TBARS levels in breast milk decreased, which might indicate its protective role in reducing oxidative stress in newborns.

  19. Modeling and simulation of blast-induced, early-time intracranial wave physics leading to traumatic brain injury.

    Energy Technology Data Exchange (ETDEWEB)

    Ford, Corey C. (University of New Mexico, Albuquerque, NM); Taylor, Paul Allen

    2008-02-01

    The objective of this modeling and simulation study was to establish the role of stress wave interactions in the genesis of traumatic brain injury (TBI) from exposure to explosive blast. A high resolution (1 mm{sup 3} voxels), 5 material model of the human head was created by segmentation of color cryosections from the Visible Human Female dataset. Tissue material properties were assigned from literature values. The model was inserted into the shock physics wave code, CTH, and subjected to a simulated blast wave of 1.3 MPa (13 bars) peak pressure from anterior, posterior and lateral directions. Three dimensional plots of maximum pressure, volumetric tension, and deviatoric (shear) stress demonstrated significant differences related to the incident blast geometry. In particular, the calculations revealed focal brain regions of elevated pressure and deviatoric (shear) stress within the first 2 milliseconds of blast exposure. Calculated maximum levels of 15 KPa deviatoric, 3.3 MPa pressure, and 0.8 MPa volumetric tension were observed before the onset of significant head accelerations. Over a 2 msec time course, the head model moved only 1 mm in response to the blast loading. Doubling the blast strength changed the resulting intracranial stress magnitudes but not their distribution. We conclude that stress localization, due to early time wave interactions, may contribute to the development of multifocal axonal injury underlying TBI. We propose that a contribution to traumatic brain injury from blast exposure, and most likely blunt impact, can occur on a time scale shorter than previous model predictions and before the onset of linear or rotational accelerations traditionally associated with the development of TBI.

  20. Combined nitrogen limitation and cadmium stress stimulate total carbohydrates, lipids, protein and amino acid accumulation in Chlorella vulgaris (Trebouxiophyceae).

    Science.gov (United States)

    Chia, Mathias Ahii; Lombardi, Ana Teresa; da Graça Gama Melão, Maria; Parrish, Christopher C

    2015-03-01

    Metals have interactive effects on the uptake and metabolism of nutrients in microalgae. However, the effect of trace metal toxicity on amino acid composition of Chlorella vulgaris as a function of varying nitrogen concentrations is not known. In this research, C. vulgaris was used to investigate the influence of cadmium (10(-7) and 2.0×10(-8)molL(-1) Cd) under varying nitrogen (2.9×10(-6), 1.1×10(-5) and 1.1×10(-3)molL(-1)N) concentrations on its growth rate, biomass and biochemical composition. Total carbohydrates, total proteins, total lipids, as well as individual amino acid proportions were determined. The combination of Cd stress and N limitation significantly inhibited growth rate and cell density of C. vulgaris. However, increasing N limitation and Cd stress stimulated higher dry weight and chlorophyll a production per cell. Furthermore, biomolecules like total proteins, carbohydrates and lipids increased with increasing N limitation and Cd stress. Ketogenic and glucogenic amino acids were accumulated under the stress conditions investigated in the present study. Amino acids involved in metal chelation like proline, histidine and glutamine were significantly increased after exposure to combined Cd stress and N limitation. We conclude that N limitation and Cd stress affects the physiology of C. vulgaris by not only decreasing its growth but also stimulating biomolecule production. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Non-Newtonian stress tensor and thermal conductivity tensor in granular plane shear flow

    Science.gov (United States)

    Alam, Meheboob; Saha, Saikat

    2014-11-01

    The non-Newtonian stress tensor and the heat flux in the plane shear flow of smooth inelastic disks are analysed from the Grad-level moment equations using the anisotropic Gaussian as a reference. Closed-form expressions for shear viscosity, pressure, first normal stress difference (N1) and the dissipation rate are given as functions of (i) the density or the area fraction (ν), (ii) the restitution coefficient (e), (iii) the dimensionless shear rate (R), (iv) the temperature anisotropy [ η, the difference between the principal eigenvalues of the second moment tensor] and (v) the angle (ϕ) between the principal directions of the shear tensor and the second moment tensor. Particle simulation data for a sheared hard-disk system is compared with theoretical results, with good agreement for p, μ and N1 over a large range of density. In contrast, the predictions from a Navier-Stokes order constitutive model are found to deviate significantly from both the simulation and the moment theory even at moderate values of e. We show that the gradient of the deviatoric part of the kinetic stress drives a heat current and the thermal conductivity is characterized by an anisotropic 2nd rank tensor for which explicit expressions are derived.

  2. Differences in the stress distribution in the distal femur between patellofemoral joint replacement and total knee replacement: a finite element study

    Directory of Open Access Journals (Sweden)

    van Jonbergen Hans-Peter W

    2012-06-01

    Full Text Available Abstract Background Patellofemoral joint replacement is a successful treatment option for isolated patellofemoral osteoarthritis. However, results of later conversion to total knee replacement may be compromised by periprosthetic bone loss. Previous clinical studies have demonstrated a decrease in distal femoral bone mineral density after patellofemoral joint replacement. It is unclear whether this is due to periprosthetic stress shielding. The main objective of the current study was to evaluate the stress shielding effect of prosthetic replacement with 2 different patellofemoral prosthetic designs and with a total knee prosthesis. Methods We developed a finite element model of an intact patellofemoral joint, and finite element models of patellofemoral joint replacement with a Journey PFJ prosthesis, a Richards II prosthesis, and a Genesis II total knee prosthesis. For each of these 4 finite element models, the average Von Mises stress in 2 clinically relevant regions of interest were evaluated during a simulated squatting movement until 120 degrees of flexion. Results During deep knee flexion, in the anterior region of interest, the average Von Mises stress with the Journey PFJ design was comparable to the physiological knee, while reduced by almost 25% for both the Richards II design and the Genesis II total knee joint replacement design. The average Von Mises stress in the supracondylar region of interest was similar for both patellofemoral prosthetic designs and the physiological model, with slightly lower stress for the Genesis II design. Conclusions Patellofemoral joint replacement results in periprosthetic stress-shielding, although to a smaller degree than in total knee replacement. Specific patellofemoral prosthetic design properties may result in differences in femoral stress shielding.

  3. Differences in the stress distribution in the distal femur between patellofemoral joint replacement and total knee replacement: a finite element study

    Science.gov (United States)

    2012-01-01

    Background Patellofemoral joint replacement is a successful treatment option for isolated patellofemoral osteoarthritis. However, results of later conversion to total knee replacement may be compromised by periprosthetic bone loss. Previous clinical studies have demonstrated a decrease in distal femoral bone mineral density after patellofemoral joint replacement. It is unclear whether this is due to periprosthetic stress shielding. The main objective of the current study was to evaluate the stress shielding effect of prosthetic replacement with 2 different patellofemoral prosthetic designs and with a total knee prosthesis. Methods We developed a finite element model of an intact patellofemoral joint, and finite element models of patellofemoral joint replacement with a Journey PFJ prosthesis, a Richards II prosthesis, and a Genesis II total knee prosthesis. For each of these 4 finite element models, the average Von Mises stress in 2 clinically relevant regions of interest were evaluated during a simulated squatting movement until 120 degrees of flexion. Results During deep knee flexion, in the anterior region of interest, the average Von Mises stress with the Journey PFJ design was comparable to the physiological knee, while reduced by almost 25% for both the Richards II design and the Genesis II total knee joint replacement design. The average Von Mises stress in the supracondylar region of interest was similar for both patellofemoral prosthetic designs and the physiological model, with slightly lower stress for the Genesis II design. Conclusions Patellofemoral joint replacement results in periprosthetic stress-shielding, although to a smaller degree than in total knee replacement. Specific patellofemoral prosthetic design properties may result in differences in femoral stress shielding. PMID:22704638

  4. Trench motion-controlled slab morphology and stress variations: Implications for the isolated 2015 Bonin Islands deep earthquake

    Science.gov (United States)

    Yang, Ting; Gurnis, Michael; Zhan, Zhongwen

    2017-07-01

    The subducted old and cold Pacific Plate beneath the young Philippine Sea Plate at the Izu-Bonin trench over the Cenozoic hosts regional deep earthquakes. We investigate slab morphology and stress regimes under different trench motion histories with mantle convection models. Viscosity, temperature, and deviatoric stress are inherently heterogeneous within the slab, which we link to the occurrence of isolated earthquakes. Models expand on previous suggestions that observed slab morphology variations along the Izu-Bonin subduction zone, exhibited as shallow slab dip angles in the north and steeper dip angles in the south, are mainly due to variations in the rate of trench retreat from the north (where it is fast) to the south (where it is slow). Geodynamic models consistent with the regional plate tectonics, including oceanic plate age, plate convergence rate, and trench motion history, reproduce the seismologically observed principal stress direction and slab morphology. We suggest that the isolated 680 km deep, 30 May 2015 Mw 7.9 Bonin Islands earthquake, which lies east of the well-defined Benioff zone and has its principal compressional stress direction oriented toward the tip of the previously defined Benioff zone, can be explained by Pacific slab buckling in response to the slow trench retreat.

  5. Active stress from earthquake focal mechanisms along the Padan-Adriatic side of the Northern Apennines (Italy), with considerations on stress magnitudes and pore-fluid pressures

    Science.gov (United States)

    Boncio, Paolo; Bracone, Vito

    2009-10-01

    The active tectonic regime along the outer Northern Apennines (Padan-Adriatic area) is a matter of debate. We analyse the active tectonic regime by systematically inverting earthquake focal mechanisms in terms of their driving stress field, comparing two different stress inversion methods. Earthquakes within the area often deviate from Andersonian conditions, being characterized by reverse or transpressional slip on high-angle faults even if the regime is almost purely thrust faulting (e.g. Reggio Emilia 1996 and Faenza 2000 earthquakes). We analyse the stress conditions at faulting for the Reggio Emilia and Faenza earthquakes in order to infer the stress magnitudes and the possible role of fluid pressures. The stress analysis defines a consistent pattern of sub-horizontal active deviatoric compression arranged nearly perpendicular to the eastern front of the Padan-Adriatic fold-and-thrust system, independent of the stress inversion method used. The results are consistent with active compression operating within the Padan-Adriatic belt. The stress field is thrust faulting (sub-vertical σ3), except for the Cesena-Forlì and Ancona areas, where a strike-slip regime (sub-vertical or steeply-plunging σ2) operates. The strike-slip regimes are interpreted as being caused by the superposition of local tensional stresses due to oroclinal bending (i.e. rotations of the belt about vertical axes) on the regional compressional stress field. Kinematic complexities characterize the 1996 Reggio Emilia seismic sequence. The distribution of these complexities is not random, suggesting that they are due to local variations of the regional stress field within the unfaulted rocks surrounding the coseismic rupture. The stress conditions at faulting for the Reggio Emilia 1996 and Faenza 2000 earthquakes, coupled with the observation that seismicity in the Padan-Adriatic area often occurs in swarms, suggest that high pore-fluid pressures (Pf ≥ 70% of the lithostatic load) operate

  6. High-resolution mapping of yield curve shape and evolution for high porosity sandstones

    Science.gov (United States)

    Bedford, J. D.; Faulkner, D.; Wheeler, J.; Leclere, H.

    2017-12-01

    The onset of permanent inelastic deformation for porous rock is typically defined by a yield curve plotted in P-Q space, where P is the effective mean stress and Q is the differential stress. Sandstones usually have broadly elliptical shaped yield curves, with the low pressure side of the ellipse associated with localized brittle faulting (dilation) and the high pressure side with distributed ductile deformation (compaction). However recent works have shown that these curves might not be perfectly elliptical and that significant evolution in shape occurs with continued deformation. We therefore use a novel stress-probing methodology to map in high-resolution the yield curve shape for Boise and Idaho Gray sandstones (36-38% porosity) and also investigate curve evolution with increasing deformation. The data reveal yield curves with a much flatter geometry than previously recorded for porous sandstone and that the compactive side of the curve is partly comprised of a near vertical limb. The yield curve evolution is found to be strongly dependent on the nature of inelastic strain. Samples that were compacted under a deviatoric load, with a component of inelastic shear strain, were found to have yield curves with peaks that are approximately 50% higher than similar porosity samples that were hydrostatically compacted (i.e. purely volumetric strain). The difference in yield curve evolution along the different loading paths is attributed to mechanical anisotropy that develops during deviatoric loading by the closure of preferentially orientated fractures. Increased shear strain also leads to the formation of a plateau at the peak of the yield curve as samples deform along the deviatoric loading path. These results have important implications for understanding how the strength of porous rock evolves along different stress paths, including during fluid extraction from hydrocarbon reservoirs where the stress state is rarely isotropic.

  7. Decreased total antioxidant capacity and increased oxidative stress in passive smoker infants and their mothers.

    Science.gov (United States)

    Aycicek, Ali; Erel, Ozcan; Kocyigit, Abdurrahim

    2005-12-01

    Smoking has many adverse health effects in infants and adults. The purpose of the study was to study the effect of passive cigarette smoking on oxidative and antioxidative status of plasma in passive smoker infants and their mothers and to compare with those of non-smokers. Subjects were randomly chosen from infants aged 8-26 weeks and their mothers aged 20-34 years. Passive smoker infants (n = 29) and their mothers (n = 29) were defined as having other family members who smoked six or more cigarettes per day continually for at least 8 weeks. Non-smokers were defined as infants (n = 30) and their mothers (n = 24) who had never been exposed to passive smoking. The antioxidative status of plasma were perused by measuring the total antioxidant capacity. Oxidative status was evaluated by predicating total peroxide level, oxidative stress index, protein oxidation and lipid peroxidation. Plasma concentrations of total antioxidant capacity were significantly lower in passive smoker infants and their mothers than non-passive smoker infants and their mothers. However, lipid peroxidation and oxidative stress index were remarkably higher in passive smoker infants and their mothers than those of non-passive smoker infants and their mothers. There were significant correlations between the oxidative and antioxidative parameters of the passive smoker infants and their mothers. Oxidants are increased and antioxidants are decreased in passive smoker infants and their mothers than those of non-smokers. Passive smoker infants and their mothers are exposed to potent oxidative stress.

  8. Plasma oxidative stress and total thiol levels in Crimean-Congo hemorrhagic fever.

    Science.gov (United States)

    Karadag-Oncel, Eda; Erel, Ozcan; Ozsurekci, Yasemin; Caglayik, Dilek Yagci; Kaya, Ali; Gozel, Mustafa Gokhan; Icagasioglu, Fusun Dilara; Engin, Aynur; Korukluoglu, Gulay; Uyar, Yavuz; Elaldi, Nazif; Ceyhan, Mehmet

    2014-01-01

    In this study, we investigated the pro- and antioxidant status of patients with a pathogenesis of Crimean-Congo hemorrhagic fever (CCHF) in terms of their role in its pathogenesis. During the study period, 34 children and 41 adults were diagnosed with CCHF. The control group consisted of healthy age- and gender-matched children and adults. Serum levels of the total antioxidant capacity (TAC), total oxidant status (TOS), oxidative stress index (OSI), and plasma total thiol (TTL) were evaluated and compared between groups. The difference in mean TAC values between CCHF patients and healthy controls was not statistically significant (P > 0.05). Mean TOS, OSI, and TTL values were significantly lower in CCHF patients than in healthy controls (P 0.05). Our results suggest that TTL may play a more important role in CCHF pathogenesis than the other parameters investigated. The mean TOS and OSI values were higher in the control group than in CCHF patients.

  9. One- and multistage total strain and stress-controlled fatigue tests with a steel of type 42 CrMo 4 subject to varied residual and mean stress loading. Final report

    International Nuclear Information System (INIS)

    Macherauch, E.; Schulze, V.

    1995-01-01

    Work under this research project covered tests with the quenched and tempered steel 42 CrMo 4 to which one- and two-stage tension-compression fatigue stresses were applied with varying mean loads, under conditions of nominal stress and total strain control. Shot peening was used to induce various microstructural conditions in the material at the surface and near below. Softening in the material was observed to be a continuous process, and the steel showed no stabilised, cyclic deformation behaviour. The cyclic stress-strain curve measured with equal stress amplitudes and total strain control applied shows higher plastic strain amplitudes than that measured with nominal stresses. The fatigue behaviour under two-stage loading depends on the chosen sequence of loads applied, the testing periods, and the overall testing procedure, so that there is no way of deriving data for two-stage testing procedures from single-stage test results. (orig.) [de

  10. Tibiofemoral contact stress and stress distribution evaluation of total knee arthroplasties.

    Science.gov (United States)

    Szivek, J A; Cutignola, L; Volz, R G

    1995-08-01

    The Fuji film (Itochu, Los Angeles, CA) area analysis technique demonstrates that a more accurate assessment of tibiofemoral contact stresses is possible when the film is used at 37 degrees C and at the upper end of its sensitivity range (in this case, a 2,000-N load). An AMK with a regular and Hylamer-M insert (DePuy, Warsaw, IN), an MG II (Zimmer, Warsaw, IN), an Omnifit (Osteonics, Allendale, NJ), an Ortholoc III (Dow Corning Wright, Midland, MI), a PCA II (Howmedica, Rutherford, NJ), and a PFC (Johnson & Johnson Orthopaedics, Raynham, MA) had average contact stresses that varied only 12% at 60 degrees flexion. At 0 degrees, 15 degrees and 60 degrees flexion, stresses ranged from 13 to 25 MPa. Contact area distribution ratios, which were smaller at 37 degrees C than at 24 degrees C, provide a quantitative means of grouping implants according to the shape of the tibiofemoral contact area. The Omnifit, MG II, PCA II, and PFC had small ratios (symmetric areas). The AMK and Ortholoc III had large ratios (asymmetric contact areas). If the impression is reflective of wear, it would be expected to be focal in knees with small ratios and contact areas, and uniform in knees with large ratios and contact areas, whereas large ratios and small areas would imply a linear wear pattern. Calibrated electrical resistance contact stress measurements indicated that the Fuji film measurements underestimated the magnitude of contact stresses. They also provided a means of quantifying the rate of area increase during initial loading of the knees, with the highest area increase noted for the knee with the roughest insert (Ortholoc III) and the lowest area increase for the knee with the smoothest insert (PCA II).

  11. Characterization of Shear Properties for APO/MBI Syntactic Foam

    Energy Technology Data Exchange (ETDEWEB)

    Reser, Patrick M. [Univ. of New Mexico, Albuquerque, NM (United States); Lewis, Matthew W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Clark, Jarod [Univ. of New Mexico, Albuquerque, NM (United States); Ahuja, Nishant [Univ. of New Mexico, Albuquerque, NM (United States); Lenke, Lary R. [Univ. of New Mexico, Albuquerque, NM (United States)

    2017-12-14

    Triaxial compression testing is a means for mechanical characterization of a material. A unique feature of the triaxial compression test is the application of two different magnitudes of compressive pressures on the material simultaneously. The material behavior under these different compressive pressures can be monitored over time. Several important characteristics of the material, such as stress yield values and the shear failure envelope may then be determined. Also mechanical properties such as Poisson’s ratio, Young’s modulus and bulk modulus can be determined from the triaxial compression test. The triaxial compression test was employed in this investigation to characterize the shear behavior, shear failure envelope, and mechanical properties of a syntactic foam. Los Alamos National Laboratory (LANL) supplied a total of 36 samples of APO-BMI syntactic foam to the University of New Mexico, Department of Civil Engineering for testing between December 2003 and May 2004. Each sample had a diameter of 1.395±0.005 in. (3.543±0.013cm.) and a length of 2.796±0.004 in. (7.102±0.010 cm.). The samples had an average density of 0.295 g/cm3. Additional information about the material tested in this investigation can be found in the “Specimen Description” section contained in Chapter 1. The nomenclatures used in this study is presented in Chapter 1. In addition to designing and implementing triaxial compression tests capable of up to 2,000 psi. confining pressure (minor principal stress) and roughly 13,000 psi. in axial pressure (major principal stress), a pure tension test was designed and conducted on the foam material. The purpose of this pure tension test was to obtain maximum tensile stress values to enhance the characterization of the shear envelope in the stress space. The sampling procedure and specimen preparation for a standard test can be found in the American Society for Testing Materials (ASTM) D 5379/ D 5379 – 93. The above tests mentioned and

  12. Anisotropic plastic deformation by viscous flow in ion tracks

    NARCIS (Netherlands)

    van Dillen, T; Polman, A; Onck, PR; van der Giessen, E

    2005-01-01

    A model describing the origin of ion beam-induced anisotropic plastic deformation is derived and discussed. It is based on a viscoelastic thermal spike model for viscous flow in single ion tracks derived by Trinkaus and Ryazanov. Deviatoric (shear) stresses, brought about by the rapid thermal

  13. Bilateral periprosthetic tibial stress fracture after total knee arthroplasty: A case report.

    Science.gov (United States)

    Ozdemir, Guzelali; Azboy, Ibrahim; Yilmaz, Baris

    2016-01-01

    Periprosthetic fractures around the knee after total knee arthroplasty can be seen in the femur, tibia and patella. The tibial fractures are rare cases. Our case with bilateral tibial stress fracture developed after total knee arthroplasty (TKA) is the first of its kind in the literature. 75-year-old male patient with bilateral knee osteoarthritis had not benefited from conservative treatment methods previously applied. Left TKA was applied. In the second month postoperatively, periprosthetic tibial fracture was identified and osteosynthesis was implemented with locked tibia proximal plate-screw. Bone union in 12 weeks was observed in his follow-ups. After 15 months of his first operation, TKA was applied to the right knee. Postoperatively in the second month, as in the first operation, periprosthetic tibial fracture was detected. Osteosynthesis with locking plate-screw was applied and union in 12 weeks was observed in his follow-up. He was seen mobilized independently and without support in the last control of the case made in the 24th month after the second operation. The number of TKA applications is expected to increase in the future. The incidence of periprosthetic fractures should also be expected to increase in these cases. Periprosthetic tibial fractures after TKA are rarely seen. The treatment of periprosthetic fractures around the knee after TKA can be difficult. In the case of persistent pain in the upper end of the tibia after the surgery, stress fracture should be considered. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Plastic flow in weak shock waves in uranium

    International Nuclear Information System (INIS)

    Tonks, D.L.

    1992-01-01

    Measurements of the particle velocity in weak shock waves in metals are available for a number of materials. These measurements use the laser interferometer or VISAR technique in conjunction with a plate impact experiment. These measurements are important for determining the elastic -- plastic behavior of materials at high strain rates. Strain rates up to 10 7 /s are measurable with this technique, while more conventional mechanical testing machines, such as the Hopkinson bar, achieve rates only up to about 10 4 /s. In this paper, the VISAR measurements of Grady on uranium are analyzed using the weak shock analysis of Wallace to extract the plastic and total strains, the deviatoric and total stresses, and the plastic strain rates. A brief error analysis of the results will be given. 7 refs

  15. Investigation of Catalase, Proxidase and Total Protein Level in Some Cold Treated Grapevine Cultivars Cold Stress Response

    Directory of Open Access Journals (Sweden)

    M. Karimi Alavijeh

    2016-02-01

    Full Text Available Chilling is an important environmental stress that influences the yield and quality of many agricultural crops. Different plants use different systems to endure this stress and minimize its effects. One of these systems is enzymatic reaction. To find out more about responses of different grapevine species and cultivars to the low temperature conditions, their enzymatic changes were evaluated in a factorial experiment based on randomized complete design with 3 replication during different periods after chilling stress. Leaf samples of plants under cold stress had been taken and maintained in -80 °C until enzyme extraction. Low temperature around 4 °C is sufficient to induce genes that produce chilling acclimatization proteins. In the present study, leaf samples were collected from the plants that were kept at 4 °C during different time intervals, and then total proteins as well as two main antioxidant enzymes (catalase and guaiacolperoxidase activities were measured. Results showed that as temperature decreased, enzymatic activities were increased in six Iranian grapevine cultivars (‘Atabaki’, ‘Khalili-Danedar’, ‘Shahroodi’, ‘Rajabi-Siah’, ‘Askari’ and ‘Bidane-Sefid’ as well as ‘Riparia’, an American species. The highest enzymatic activities of catalase and ceroxidase were recorded in ‘Khalili-Danedar’ and ‘Riparia’. However,the lowest activities were recorded in ‘Rajabi-Siah’, ‘Bidane-Sefid’ and ‘Shahroodi’. For all studied cultivars, peroxidase showed its highest activity at 12 h after chilling stress, then remained constant, while, the highest activity of catalase were recorded at 8 h. In addition, cold stress increased the total protein content for all studied cultivars, in which ‘Khalili-Danedar’ had the highest protein content amongstudied cultivars. Also, the highest proteins content were recorded at 12 h after exposing plants to cold.

  16. Inversion of calcite twin data for paleostress orientations and magnitudes: A new technique tested and calibrated on numerically-generated and natural data

    Science.gov (United States)

    Parlangeau, Camille; Lacombe, Olivier; Schueller, Sylvie; Daniel, Jean-Marc

    2018-01-01

    The inversion of calcite twin data is a powerful tool to reconstruct paleostresses sustained by carbonate rocks during their geological history. Following Etchecopar's (1984) pioneering work, this study presents a new technique for the inversion of calcite twin data that reconstructs the 5 parameters of the deviatoric stress tensors from both monophase and polyphase twin datasets. The uncertainties in the parameters of the stress tensors reconstructed by this new technique are evaluated on numerically-generated datasets. The technique not only reliably defines the 5 parameters of the deviatoric stress tensor, but also reliably separates very close superimposed stress tensors (30° of difference in maximum principal stress orientation or switch between σ3 and σ2 axes). The technique is further shown to be robust to sampling bias and to slight variability in the critical resolved shear stress. Due to our still incomplete knowledge of the evolution of the critical resolved shear stress with grain size, our results show that it is recommended to analyze twin data subsets of homogeneous grain size to minimize possible errors, mainly those concerning differential stress values. The methodological uncertainty in principal stress orientations is about ± 10°; it is about ± 0.1 for the stress ratio. For differential stresses, the uncertainty is lower than ± 30%. Applying the technique to vein samples within Mesozoic limestones from the Monte Nero anticline (northern Apennines, Italy) demonstrates its ability to reliably detect and separate tectonically significant paleostress orientations and magnitudes from naturally deformed polyphase samples, hence to fingerprint the regional paleostresses of interest in tectonic studies.

  17. Shock wave plasticity in Mo at 293K and 1673K

    International Nuclear Information System (INIS)

    Tonks, D.L.

    1996-01-01

    The shock wave plasticity of Mo is extracted from two VISAR wave profiles; of about 110 kbar strength at 293 K and of about 120 kbar strength at 1673 K. The Wallace weak shock analysis is used to obtain the plastic strain and deviatoric stress, and the normal stress and volumetric strain, through the shock rise from the velocity profile data. The Wallace analysis uses the steady wave assumption for the plastic portion of the shock rise, a plausible evolution for the precursor portion, a thermoelastic model, and the mechanical equations of motion. Comparison of the high and low temperature results is of interest in assessing the mechanisms of plastic flow. In the results, the (von Mises equivalent) peak deviatoric stresses are 12.8 kbar and 20.3 kbar, for the hot and cold Mo, respectively, while the peak plastic strain rate of the hot Mo is about 2.6 times that of the cold Mo. These values rule out thermal activation. In addition, they are not consistent with a simple phonon viscosity linear in the temperature. Additional effects are needed to explain the results, e.g. evolution of the mobile dislocation density. copyright 1996 American Institute of Physics

  18. Rhynchophylla total alkaloid rescues autophagy, decreases oxidative stress and improves endothelial vasodilation in spontaneous hypertensive rats.

    Science.gov (United States)

    Li, Chao; Jiang, Feng; Li, Yun-Lun; Jiang, Yue-Hua; Yang, Wen-Qing; Sheng, Jie; Xu, Wen-Juan; Zhu, Qing-Jun

    2018-03-01

    Autophagy plays an important role in alleviating oxidative stress and stabilizing atherosclerotic plaques. However, the potential role of autophagy in endothelial vasodilation function has rarely been studied. This study aimed to investigate whether rhynchophylla total alkaloid (RTA) has a positive role in enhancing autophagy through decreasing oxidative stress, and improving endothelial vasodilation. In oxidized low-density lipoprotein (ox-LDL)-treated human umbilical vein endothelial cells (HUVECs), RTA (200 mg/L) significantly suppressed ox-LDL-induced oxidative stress through rescuing autophagy, and decreased cell apoptosis. In spontaneous hypertensive rats (SHR), administration of RTA (50 mg·kg -1 ·d -1 , ip, for 6 weeks) improved endothelin-dependent vasodilation of thoracic aorta rings. Furthermore, RTA administration significantly increased the antioxidant capacity and alleviated oxidative stress through enhancing autophagy in SHR. In ox-LDL-treated HUVECs, we found that the promotion of autophagy by RTA resulted in activation of the AMP-activated protein kinase (AMPK) signaling pathway. Our results show that RTA treatment rescues the ox-LDL-induced autophagy impairment in HUVECs and improves endothelium-dependent vasodilation function in SHR.

  19. Sustained delivery of exogenous melatonin influences biomarkers of oxidative stress and total antioxidant capacity in summer-stressed anestrous water buffalo (Bubalus bubalis).

    Science.gov (United States)

    Kumar, Ashok; Mehrotra, S; Singh, G; Narayanan, K; Das, G K; Soni, Y K; Singh, Mahak; Mahla, A S; Srivastava, N; Verma, M R

    2015-06-01

    High ambient temperature during summer in tropical and subtropical countries predisposes water buffaloes (Bubalus bubalis) to develop oxidative stress having antigonadotropic and antisteroidogenic actions. Melatonin is a regulator of seasonal reproduction in photoperiodic species and highly effective antioxidant and free radical scavenger. Therefore, a study was designed to evaluate the effect of sustained-release melatonin on biomarkers of oxidative stress i.e., the serum malondialdehyde (MDA) and nitric oxide (NO), and the total antioxidant capacity (TAC). For the study, postpartum buffaloes diagnosed as summer anestrus (absence of overt signs of estrus, concurrent rectal examination, and RIA for serum progesterone) were grouped as treated (single subcutaneous injection of melatonin at 18 mg/50 kg body weight dissolved in sterilized corn oil as vehicle, n = 20) and untreated (subcutaneous sterilized corn oil, n = 8). Blood sampling for estimation of serum TAC and MDA (mmol/L) and NO (μmol/L) was carried out at 4 days of interval from 8 days before treatment till 28 days after treatment or for the ensuing entire cycle length. Results showed serum TAC concentration was higher in the treatment group with a significant (P stress resulting in the induction of cyclicity in summer-stressed anestrous buffaloes. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. A nominally second-order cell-centered Lagrangian scheme for simulating elastic-plastic flows on two-dimensional unstructured grids

    Science.gov (United States)

    Maire, Pierre-Henri; Abgrall, Rémi; Breil, Jérôme; Loubère, Raphaël; Rebourcet, Bernard

    2013-02-01

    In this paper, we describe a cell-centered Lagrangian scheme devoted to the numerical simulation of solid dynamics on two-dimensional unstructured grids in planar geometry. This numerical method, utilizes the classical elastic-perfectly plastic material model initially proposed by Wilkins [M.L. Wilkins, Calculation of elastic-plastic flow, Meth. Comput. Phys. (1964)]. In this model, the Cauchy stress tensor is decomposed into the sum of its deviatoric part and the thermodynamic pressure which is defined by means of an equation of state. Regarding the deviatoric stress, its time evolution is governed by a classical constitutive law for isotropic material. The plasticity model employs the von Mises yield criterion and is implemented by means of the radial return algorithm. The numerical scheme relies on a finite volume cell-centered method wherein numerical fluxes are expressed in terms of sub-cell force. The generic form of the sub-cell force is obtained by requiring the scheme to satisfy a semi-discrete dissipation inequality. Sub-cell force and nodal velocity to move the grid are computed consistently with cell volume variation by means of a node-centered solver, which results from total energy conservation. The nominally second-order extension is achieved by developing a two-dimensional extension in the Lagrangian framework of the Generalized Riemann Problem methodology, introduced by Ben-Artzi and Falcovitz [M. Ben-Artzi, J. Falcovitz, Generalized Riemann Problems in Computational Fluid Dynamics, Cambridge Monogr. Appl. Comput. Math. (2003)]. Finally, the robustness and the accuracy of the numerical scheme are assessed through the computation of several test cases.

  1. NW transverse fault system in Southern Bogota, Colombia: New seismologic and structural evidences derived from focal mechanisms and stress field determination

    Science.gov (United States)

    Angel Amaya, J.; Fierro Morales, J.; Ordoñez Potes, M.; Blanco, M.

    2012-12-01

    We present new seismological, morphotectonic and structural data of the Southern Bogota area. The goals of the study were to characterize the NW transverse fault system and to evaluate its effect on seismic wave's generation and propagation. The data set included epicenters of the RSNC (Red Sismologica Nacional de Colombia) catalog over the period 1993-2012, historical description of seismic events (period 1644-1921), structural field data (scale 1:100000) and remote sensors interpretation. The methodology included the structural analysis of over 476 faults having a known sense of offset by using a least squares iterative inversion outlined by Angelier (1984) to determinate the mean deviatoric principal stress tensor. Preliminary conclusions showed that both propagation medium and direction are determined by the structural and mechanic conditions of the Southern Bogota Shear Zone (SBSZ) defined by Fierro & Angel, (2008) as a NW-SE oblique-slip fault zone within sinistral and normal regimes. Based on both data sources (focal mechanism and field structural data) we attempted to reconstruct the stress field starting with a strike slip faulting stress regime (S2 vertical), the solution yielded a ENE-WSW orientation for horizontal principal stress (S1). It is hypothesized that the NW oblique-slip fault zone may generate and/or propagate seismic waves, as a local source, implying local hazard to Bogota the capital city of Colombia with over 8 million habitants.

  2. Cement stress predictions after anatomic total shoulder arthroplasty are correlated with preoperative glenoid bone quality.

    Science.gov (United States)

    Terrier, Alexandre; Obrist, Raphaël; Becce, Fabio; Farron, Alain

    2017-09-01

    We hypothesized that biomechanical parameters typically associated with glenoid implant failure after anatomic total shoulder arthroplasty (aTSA) would be correlated with preoperative glenoid bone quality. We developed an objective automated method to quantify preoperative glenoid bone quality in different volumes of interest (VOIs): cortical bone, subchondral cortical plate, subchondral bone after reaming, subchondral trabecular bone, and successive layers of trabecular bone. Average computed tomography (CT) numbers (in Hounsfield units [HU]) were measured in each VOI from preoperative CT scans. In parallel, we built patient-specific finite element models of simulated aTSAs to predict cement stress, bone-cement interfacial stress, and bone strain around the glenoid implant. CT measurements and finite element predictions were obtained for 20 patients undergoing aTSA for primary glenohumeral osteoarthritis. We tested all linear correlations between preoperative patient characteristics (age, sex, height, weight, glenoid bone quality) and biomechanical predictions (cement stress, bone-cement interfacial stress, bone strain). Average CT numbers gradually decreased from cortical (717 HU) to subchondral and trabecular (362 HU) bone. Peak cement stress (4-10 MPa) was located within the keel hole, above the keel, or behind the glenoid implant backside. Cement stress, bone-cement interfacial stress, and bone strain were strongly negatively correlated with preoperative glenoid bone quality, particularly in VOIs behind the implant backside (subchondral trabecular bone) but also in deeper trabecular VOIs. Our numerical study suggests that preoperative glenoid bone quality is an important parameter to consider in aTSA, which may be associated with aseptic loosening of the glenoid implant. These initial results should now be confronted with clinical and radiologic outcomes. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc

  3. Sleep deprived and sweating it out: the effects of total sleep deprivation on skin conductance reactivity to psychosocial stress.

    Science.gov (United States)

    Liu, Jean C J; Verhulst, Silvan; Massar, Stijn A A; Chee, Michael W L

    2015-01-01

    We examined how sleep deprivation alters physiological responses to psychosocial stress by evaluating changes in skin conductance. Between-subjects design with one group allocated to 24 h of total sleep deprivation and the other to rested wakefulness. The study took place in a research laboratory. Participants were 40 healthy young adults recruited from a university. Sleep deprivation and feedback. Electrodermal activity was monitored while participants completed a difficult perceptual task with false feedback. All participants showed increased skin conductance levels following stress. However, compared to well-rested participants, sleep deprived participants showed higher skin conductance reactivity with increasing stress levels. Our results suggest that sleep deprivation augments allostatic responses to increasing psychosocial stress. Consequentially, we propose sleep loss as a risk factor that can influence the pathogenic effects of stress. © 2014 Associated Professional Sleep Societies, LLC.

  4. Electromigration-induced plastic deformation in passivated metal lines

    Science.gov (United States)

    Valek, B. C.; Bravman, J. C.; Tamura, N.; MacDowell, A. A.; Celestre, R. S.; Padmore, H. A.; Spolenak, R.; Brown, W. L.; Batterman, B. W.; Patel, J. R.

    2002-11-01

    We have used scanning white beam x-ray microdiffraction to study microstructural evolution during an in situ electromigration experiment on a passivated Al(Cu) test line. The data show plastic deformation and grain rotations occurring under the influence of electromigration, seen as broadening, movement, and splitting of reflections diffracted from individual metal grains. We believe this deformation is due to localized shear stresses that arise due to the inhomogeneous transfer of metal along the line. Deviatoric stress measurements show changes in the components of stress within the line, including relaxation of stress when current is removed.

  5. Total Glucosides of Danggui Buxue Tang Attenuate BLM-Induced Pulmonary Fibrosis via Regulating Oxidative Stress by Inhibiting NOX4

    Science.gov (United States)

    Zhao, Ping; Zhou, Wen-Cheng; Li, De-Lin; Mo, Xiao-Ting; Xu, Liang; Li, Liu-Cheng; Cui, Wen-Hui; Gao, Jian

    2015-01-01

    Pulmonary fibrosis (PF) is a serious chronic lung disease with unknown pathogenesis. Researches have confirmed that oxidative stress which is regulated by NADPH oxidase-4 (NOX4), a main source of reactive oxygen species (ROS), is an important molecular mechanism underlying PF. Previous studies showed that total glucosides of Danggui Buxue Tang (DBTG), an extract from a classical traditional Chinese herbal formula, Danggui Buxue Tang (DBT), attenuated bleomycin-induced PF in rats. However, the mechanisms of DBTG are still not clear. We hypothesize that DBTG attenuates PF through regulating the level of oxidative stress by inhibiting NOX4. And we found that fibrosis indexes hydroxyproline (HYP) and type I collagen (Col-I) were lower in DBTG groups compared with the model group. In addition, the expression of transforming growth factor-β1 (TGF-β1) and expression of alpha smooth muscle actin (α-SMA) were also much more decreased than the model group. For oxidative stress indicators, DBTG blunted the decrease of superoxide dismutase (SOD) activity, total antioxidant capacity (T-AOC), and the increase in malondialdehyde (MDA), 8-iso-prostaglandin in lung homogenates. Treatment with DBTG restrained the expression of NOX4 compared to the model group. Present study confirms that DBTG inhibits BLM-induced PF by modulating the level of oxidative stress via suppressing NOX4. PMID:26347805

  6. Increased risk of attempted suicide in Australian veterans is associated with total and permanent incapacitation, unemployment and posttraumatic stress disorder severity.

    Science.gov (United States)

    Kerr, Katelyn; Romaniuk, Madeline; McLeay, Sarah; Khoo, Andrew; Dent, Michael T; Boshen, Mark

    2018-06-01

    Military veterans have higher rates of suicidality and completed suicides compared to the general population. Previous research has demonstrated suicidal behaviour is higher in US combat veterans who are younger, suffer from posttraumatic stress disorder, depression and anxiety and score lower on measures of health. However, research on predictors of suicide for Australian veterans is limited. The aim of this study was to identify significant demographic and psychological differences between veterans with posttraumatic stress disorder who had attempted suicide and those with posttraumatic stress disorder who had not, as well as determine predictors of suicide attempts within an Australian cohort. A retrospective analysis was conducted on 229 ex-service personnel diagnosed with posttraumatic stress disorder who had attended a Military Service Trauma Recovery Day Program as outpatients at Toowong Private Hospital from 2007 to 2014. Patients completed a battery of mental health self-report questionnaires assessing symptoms of posttraumatic stress disorder, alcohol use, anger, depression, anxiety and quality of life. Demographic information and self-reported history of suicide attempts were also recorded. Results indicated the average age was significantly lower, and the rates of posttraumatic stress disorder, anger, anxiety and depression symptoms were significantly higher in those veterans with history of a suicide attempt. Multivariate logistic regression analyses indicated posttraumatic stress disorder symptom severity, unemployment or total and permanent incapacity pension status significantly predicted suicide attempt history. Among a cohort of Australian veterans with posttraumatic stress disorder, psychopathology severity, unemployment and total and permanent incapacity status are significantly associated with suicidality. This study highlights the importance of early identification of posttraumatic stress disorder and psychopathology, therapeutic and social

  7. Implications for anomalous mantle pressure and dynamic topography from lithospheric stress patterns in the North Atlantic Realm

    Science.gov (United States)

    Schiffer, Christian; Nielsen, Søren Bom

    2016-08-01

    With convergent plate boundaries at some distance, the sources of the lithospheric stress field of the North Atlantic Realm are mainly mantle tractions at the base of the lithosphere, lithospheric density structure and topography. Given this, we estimate horizontal deviatoric stresses using a well-established thin sheet model in a global finite element representation. We adjust the lithospheric thickness and the sub-lithospheric pressure iteratively, comparing modelled in plane stress with the observations of the World Stress Map. We find that an anomalous mantle pressure associated with the Iceland and Azores melt anomalies, as well as topography are able to explain the general pattern of the principle horizontal stress directions. The Iceland melt anomaly overprints the classic ridge push perpendicular to the Mid Atlantic ridge and affects the conjugate passive margins in East Greenland more than in western Scandinavia. The dynamic support of topography shows a distinct maximum of c. 1000 m in Iceland and amounts <150 m along the coast of south-western Norway and 250-350 m along the coast of East Greenland. Considering that large areas of the North Atlantic Realm have been estimated to be sub-aerial during the time of break-up, two components of dynamic topography seem to have affected the area: a short-lived, which affected a wider area along the rift system and quickly dissipated after break-up, and a more durable in the close vicinity of Iceland. This is consistent with the appearance of a buoyancy anomaly at the base of the North Atlantic lithosphere at or slightly before continental breakup, relatively fast dissipation of the fringes of this, and continued melt generation below Iceland.

  8. The transmission of stress to grafted bone inside a titanium mesh cage used in anterior column reconstruction after total spondylectomy: a finite-element analysis.

    Science.gov (United States)

    Akamaru, Tomoyuki; Kawahara, Norio; Sakamoto, Jiro; Yoshida, Akira; Murakami, Hideki; Hato, Taizo; Awamori, Serina; Oda, Juhachi; Tomita, Katsuro

    2005-12-15

    A finite-element study of posterior alone or anterior/posterior combined instrumentation following total spondylectomy and replacement with a titanium mesh cage used as an anterior strut. To compare the effect of posterior instrumentation versus anterior/posterior instrumentation on transmission of the stress to grafted bone inside a titanium mesh cage following total spondylectomy. The most recent reconstruction techniques following total spondylectomy for malignant spinal tumor include a titanium mesh cage filled with autologous bone as an anterior strut. The need for additional anterior instrumentation with posterior pedicle screws and rods is controversial. Transmission of the mechanical stress to grafted bone inside a titanium mesh cage is important for fusion and remodeling. To our knowledge, there are no published reports comparing the load-sharing properties of the different reconstruction methods following total spondylectomy. A 3-dimensional finite-element model of the reconstructed spine (T10-L4) following total spondylectomy at T12 was constructed. A Harms titanium mesh cage (DePuy Spine, Raynham, MA) was positioned as an anterior replacement, and 3 types of the reconstruction methods were compared: (1) multilevel posterior instrumentation (MPI) (i.e., posterior pedicle screws and rods at T10-L2 without anterior instrumentation); (2) MPI with anterior instrumentation (MPAI) (i.e., MPAI [Kaneda SR; DePuy Spine] at T11-L1); and (3) short posterior and anterior instrumentation (SPAI) (i.e., posterior pedicle screws and rods with anterior instrumentation at T11-L1). The mechanical energy stress distribution exerted inside the titanium mesh cage was evaluated and compared by finite-element analysis for the 3 different reconstruction methods. Simulated forces were applied to give axial compression, flexion, extension, and lateral bending. In flexion mode, the energy stress distribution in MPI was higher than 3.0 x 10 MPa in 73.0% of the total volume inside

  9. Energy budgets of mining-induced earthquakes and their interactions with nearby stopes

    Science.gov (United States)

    McGarr, A.

    2000-01-01

    In the early 1960's, N.G.W. Cook, using an underground network of geophones, demonstrated that most Witwatersrand tremors are closely associated with deep level gold mining operations. He also showed that the energy released by the closure of the tabular stopes at depths of the order of 2 km was more than sufficient to account for the mining-induced earthquakes. I report here updated versions of these two results based on more modern underground data acquired in the Witwatersrand gold fields. Firstly, an extensive suite of in situ stress data indicate that the ambient state of crustal stress here is close to the failure state in the absence of mining even though the tectonic setting is thoroughly stable. Mining initially stabilizes the rock mass by reducing the pore fluid pressure from its initial hydrostatic state to nearly zero. The extensive mine excavations, as Cook showed, concentrate the deviatoric stresses, in localized regions of the abutments, back into a failure state resulting in seismicity. Secondly, there appears to be two distinct types of mining-induced earthquakes: the first is strongly coupled to the mining and involves shear failure plus a coseismic volume reduction; the second type is not evidently coupled to any particular mine face, shows purely deviatoric failure, and is presumably caused by more regional changes in the state of stress due to mining. Thirdly, energy budgets for mining induced earthquakes of both types indicate that, of the available released energy, only a few per cent is radiated by the seismic waves with the majority being consumed in overcoming fault friction. Published by Elsevier Science Ltd.In the early 1960's, N.G.W. Cook, using an underground network of geophones, demonstrated that most Witwatersrand tremors are closely associated with deep level gold mining operations. He also showed that the energy released by the closure of the tabular stopes at depths of the order of 2 km was more than sufficient to account for the

  10. [Stress analysis of femoral stems in cementless total hip arthroplasty by two-dimensional finite element method using boundary friction layer].

    Science.gov (United States)

    Oomori, H; Imura, S; Gesso, H

    1992-04-01

    To develop stem design achieving primary fixation of stems and effective load transfer to the femur, we studied stress analysis of stems in cementless total hip arthroplasty by two-dimensional finite element method using boundary friction layer in stem-bone interface. The results of analyses of stem-bone interface stresses and von Mises stresses at the cortical bones indicated that ideal stem design features would be as follows: 1) Sufficient length, with the distal end extending beyond the isthmus region. 2) Maximum possible width, to contact the cortical bones in the isthmus region. 3) No collars but a lateral shoulder at the proximal portion. 4) A distal tip, to contact the cortical bones at the distal portion.

  11. Post-Cam Design and Contact Stress on Tibial Posts in Posterior-Stabilized Total Knee Prostheses: Comparison Between a Rounded and a Squared Design.

    Science.gov (United States)

    Watanabe, Toshifumi; Koga, Hideyuki; Horie, Masafumi; Katagiri, Hiroki; Sekiya, Ichiro; Muneta, Takeshi

    2017-12-01

    The post-cam mechanism in posterior stabilized (PS) prostheses plays an important role in total knee arthroplasty (TKA). The purpose of this study is to clarify the difference of the contact stress on the tibial post between a rounded post-cam design and a squared design during deep knee flexion and at hyperextension using the three-dimensional (3D) finite element models. We created 2 types of 3D, finite element models of PS prostheses (types A and B), whose surfaces were identical except for the post-cam geometries: type A has a rounded post-cam design, while type B has a squared design. Both types have a similar curved-shape intercondylar notch of the femoral component. Stress distributions, peak contact stresses, and contact areas on the tibial posts at 90°, 120°, and 150° flexion with/without 10° tibial internal rotation and at 10° hyperextension were compared between the 2 models. Type B demonstrated more concentrated stress distribution compared to type A. The peak contact stresses were similar in both groups during neutral flexion; however, the stresses were much higher in type B during flexion with 10° rotation and at hyperextension. The higher peak contact stresses corresponded to the smaller contact areas in the tibial post. A rounded post-cam design demonstrated less stress concentration during flexion with rotation and at hyperextension compared with a squared design. The results would be useful for development of implant designs and prediction of the contact stress on the tibial post in PS total knee arthroplasty. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Impact on adenosine stress cardiac magnetic resonance for recanalisation and follow up of chronic total coronary occlusions

    Energy Technology Data Exchange (ETDEWEB)

    Heyne, J.P. [Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Jens-Peter.Heyne@med.uni-jena.de; Goernig, M. [Clinic for Internal Medicine I, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Matthias.Goernig@med.uni-jena.de; Feger, J. [Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Joachim.Feger@email.de; Kurrat, C. [Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Claudia.Kurrat@med.uni-jena.de; Werner, G.S. [Clinic for Internal Medicine I, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Gerald.Werner@Klinikum-Darmstadt.de; Figulla, H.R. [Clinic for Internal Medicine I, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Hans.Figulla@med.uni-jena.de; Kaiser, W.A. [Institute of Diagnostic and Interventional Radiology, Friedrich Schiller University Jena, Erlanger Allee 101, D-07740 Jena (Germany)], E-mail: Werner.Kaiser@med.uni-jena.de

    2007-09-15

    Objective: To evaluate the impact on cardiac magnetic resonance imaging (CMRI) with adenosine stress and delayed enhancement for indication and follow up after interventional recanalisation of chronic total coronary occlusions (CTOs). Material and methods: Twenty consecutive patients (15 males; 5 females; mean age 65 years) with CTO verified by cardiac catheterisation referred to CMRI. Sixteen of them got CMRI before and after coronary recanalisation. Wall motion abnormalities (WMAs), first pass perfusion with adenosine and viability were assessed using a 1.5 T MR scanner (Sonata; Siemens). CMRI results were compared with clinical classifications, the results of cardiac catheterisation and follow up angiography. Results: Sixteen patients had a successful recanalisation, 15 of the occluded coronary artery and one of collateral donor artery stenosis. After recanalisation all stress-induced progressive or new wall motion abnormalities (WMAs) of the corresponding segments and in the collateral donor territory (5 patients) and all adenosine induced perfusion defects (PD) or delay (12 patients) were regredient. 13/16 patients showed no transmural and one patient transmural delayed enhancement (DE) indicating myocardial scar. In 10/16 patients CSS grading of angina improved after recanalisation. Conclusion: After successful recanalisation of CTOs, patients with preinterventional stress-induced PDs and WMAs in viable myocardium did not display any signs of stress-induced ischemia postinterventionally. A comprehensive CMRI approach, including assessment of rest and stress WMAs, first pass perfusion and myocardial viability represents an important tool for the pre-interventional decision to recanalise CTOs and follow up.

  13. Application of a new thermo-mechanical model for the study of the nuclear waste disposal in clay rocks

    International Nuclear Information System (INIS)

    Dizier, A.; Li, X.L.; Francois, B.; Collin, F.; Charlier, R.

    2012-01-01

    (LY curve (Loading Yield)). This one may be considered analogous with the LC curve (Loading Collapse) met in the Barcelona Basic Model dedicated to unsaturated soil mechanics. This thermo-mechanical law has been used to model the PRACLAY experiment and particularly to analyse the evolution of the damaged zone with temperature. In this study, the damaged zone is considered as the sum of two plastic strain components, a deviatoric and a volumetric one. The deviatoric strains are induced when the internal friction criterion is reached while the volumetric strains are a consequence of the Cam - Clay model or the TY curve. The results of the evolution of the deviatoric strain show that the magnitude of this strain is modified near the wall but the extension of the size of the plastic deviatoric zone is not affected by temperature. The modification of the deviatoric strain near the wall can be explained by hydro-mechanical coupling caused by thermally induced excess pore water pressure which permits the stress path to reach the internal friction criterion. Concerning the volumetric plastic strains, these follow the effect of the thermal load and the size of the zone affected by these strains correspond to the zone affected by the temperature. On the contrary the magnitude of the strain depends on the state of stress of the clay as observed near the wall. Indeed, the stresses near the wall are reduced due to the process of excavation and the state of stress exhibits a kind of over-consolidation effect where only thermal dilation is possible. In that modelling, the set of parameters chosen doesn't allow the activation of the LY curve. Finally the results obtained with this new thermo-mechanical law have been compared with results obtained with other thermo-mechanical law, that is to say with ACMEG-T which is a thermo-plastic law developed at EPFL and a classical thermo-elastic law. The comparison shows that the results obtained with the two thermo-plastic constitutive laws

  14. Oxidative stress and lowered total antioxidant status are associated with a history of suicide attempts.

    Science.gov (United States)

    Vargas, Heber Odebrecht; Nunes, Sandra Odebrecht Vargas; Pizzo de Castro, Marcia; Bortolasci, Chiara Cristina; Sabbatini Barbosa, Décio; Kaminami Morimoto, Helena; Venugopal, Kamalesh; Dodd, Seetal; Maes, Michael; Berk, Michael

    2013-09-25

    There is evidence that depression is accompanied by inflammation, oxidative and nitrosative stress (O&NS) and metabolic disorders. However links between oxidative stress and suicide attempts in depressed patients are poorly understood. This study examines whether a history of suicide attempts is associated with inflammation, O&NS and metabolic disorders. Blood specimens were collected from study participants aged 18-60 (N=342) recruited at the State University of Londrina, Brazil, and measured for oxidative stress biomarkers: nitric oxide metabolites (NOx), lipid hydroperoxides, malondialdehyde, advanced oxidation protein products and plasma total antioxidant potential (TRAP); inflammatory biomarkers: fibrinogen, high-sensitivity C-reactive protein, erythrocyte sedimentation rate, interleukin-6 and tumor necrosis factor-α; and metabolic variables. Subjects were divided into those with (n=141) and without (n=201) a history of suicidal attempts. Individuals with a history of suicide attempts had significantly higher levels of NOx and lipid hydroperoxides and lowered TRAP as compared to individuals without suicide attempts. There were no significant associations between a history of suicide attempts and inflammatory and metabolic biomarkers and metabolic syndrome. Logistic regression showed that both unipolar and bipolar disorder, female gender, smoking behavior and lipid hydroperoxides were significantly associated with a history of suicide attempts. The combined effects of oxidative stress, smoking, depression, female gender were independent from classical risk factors, including marital status, years of education and anxiety. O&NS as well as lowered antioxidant levels may play a role in the pathophysiology of suicidal behavior independently from the effects of depression and smoking, both of which are associated with increased O&NS, and classical suicide predictors, such as years of education and marital status. © 2013 Published by Elsevier B.V.

  15. Modelling of the elastic behaviour of metallic powders

    International Nuclear Information System (INIS)

    Riera, M.D.; Prado, J.M.

    1998-01-01

    In this work the elastic behaviour of metal powders compacted to different densities is studied. The authors apply a model based on the experimental observation that the elastic volumetric strain and the hydrostatic component of the applied stress are exponentially related. While a complete analysis should include both the volumetric and deviatoric components of the elastic strain, we only present here the first one. (Author) 9 refs

  16. Dynamics of shock waves in elastic-plastic solids

    OpenAIRE

    Favrie , Nicolas; Gavrilyuk , Sergey ,

    2010-01-01

    Submitted in ESAIM Procedings; The Maxwell type elastic-plastic solids are characterized by decaying the absolute values of the principal components of the deviatoric part of the stress tensor during the plastic relaxation step. We propose a mathematical formulation of such a model which is compatible with the von Mises criterion of plasticity. Numerical examples show the ability of the model to deal with complex physical phenomena.

  17. Evaluation of Oxidative Stress and Using a Novel Automated Method For Measurement of Total Antioxidant Status in Preeclampsia

    Directory of Open Access Journals (Sweden)

    Ebru Kale

    2006-04-01

    CONCLUSIONS: Our findings suggest that preeclampsia is related with enhanced lipid peroxidation and decreased total antioxidant response before delivery and these parameters may be related at least partly to the pathogenesis of preeclampsia. Decreased lipid peroxidation and increased total antioxidant response after delivery may suggest recov ery of preeclampsia and using a simple, rapid and reliable automated method f acilitates to ev aluate and follow up of the lev els of oxidativ e stress in preeclampsia and this novel method may be used as a routine test in clinical practice while managing preeclampsia

  18. Stress-induced hyperglycaemia and venous thromboembolism following total hip or total knee arthroplasty Analysis from the RECORD trials

    NARCIS (Netherlands)

    Cohn, Danny M.; Hermanides, Jeroen; DeVries, J. Hans; Kamphuisen, Pieter-Willem; Kuhls, Silvia; Homering, Martin; Hoekstra, Joost B. L.; Lensing, Anthonie W. A.; Büller, Harry R.

    2012-01-01

    Stress-induced hyperglycaemia is common during orthopaedic surgery. In addition, hyperglycaemia activates coagulation. The aim of the study was to assess whether stress-induced hyperglycaemia is associated with symptomatic or asymptomatic venous thromboembolism (VTE) following orthopaedic surgery.

  19. Experimental study on poro-mechanical behavior of saturated Meuse-Haute/Marne argillite subjected to triaxial compression

    International Nuclear Information System (INIS)

    Hu, Dawei; Zhang, Fan; Xie, Shouyi; Shao, Jianfu

    2012-01-01

    Document available in extended abstract form only. Due to its low permeability (10 -18 to 10 -20 m 2 ), the Meuse-Haute/Marne argillite is chosen as the candidate host rock for the geological disposal of high-level radioactive waste by 'Agence Nationale de gestion des Dechets Radioactifs' (ANDRA). During the excavation of the underground tunnel in argillite formation, the Excavation Damaged Zone (EDZ) is expected to develop due to the stress redistribution during excavation and subsequent rock convergence. The nucleation and propagation of microcracks in EDZ can consequently affect the poro-mechanical behavior of the host rock. Therefore, it is of crucial importance to study the poro-mechanical behavior of Meuse-Haute/Marne argillite under the influence of stress induced microcracks. For this purpose, this paper presents the original experimental results of drained and undrained triaxial compression tests as well as evolution of Biot's coefficient during hydrostatic and deviatoric loading of saturated Meuse-Haute/Marne argillite. The size of samples used in the present work is 20x20 mm in order to reduce the saturating time. The axis of the cylindrical sample is perpendicular to the bedding planes. The test system is placed in an insulated room and a temperature control system is used to maintain a constant temperature of 20 ±0.2 C. The saturation condition is an important factor for the determination of the mechanical and poro-elastic properties of saturated argillite. Thus, for each sample, after putting into the triaxial cell, the confining pressure is loaded to 2 MPa and we inject distilled water both at the injection and outlet faces in order to insure the pore pressure at the two faces hold at 1 MPa. This procedure will be keep to 72 hours. Then, the pore pressure at the injection face is increased to 1.5 MPa, and we record the pore pressure at the outlet face. Once the pore pressure at the outlet face reaches the same value at injection face, the sample is

  20. Sensitivity of total stress to changes in externally applied water pressure in KBS-3 buffer bentonite

    Energy Technology Data Exchange (ETDEWEB)

    Harrington, J.F.; Birchall, D.J. [British Geological Survey, Chemical and Biological Hazards Programme, Kingsley Dunham Centre (United Kingdom)

    2007-04-15

    In the current Swedish repository design concept, composite copper and steel canisters containing spent nuclear fuel will be placed in large diameter disposal boreholes drilled into the floor of the repository tunnels. The space around each canister will be filled with pre-compacted bentonite which over time will draw in the surrounding ground water and swell, closing up any construction joints. However, for the purposes of performance assessment, it is necessary to consider the effect of glacial loading of a future repository and its impact on the mechanical behaviour of the bentonite, in particular, the sensitivity of total stress to changes in porewater pressure (backpressure). Two experimental histories have been undertaken using a custom-designed constant volume and radial flow (CVRF) apparatus. In both tests backpressure was varied in a number of incremental and decremental cycles while total stress, porewater pressure and volumetric flow rate were continuously monitored. The swelling pressure of the buffer clay at dry densities of 1.8 Mg/m{sup 3} and 1.61 Mg/m{sup 3} was determined to be around 5.5 MPa and 7.2 MPa respectively. For initial ascending porewater pressure histories the average proportionality factor {alpha} ranged from 0.86 and 0.92. Data exhibited a general trend of increasing {alpha} with increasing backpressure. In test Mx80-11 this was supported by analysis of the water inflow data which indicated a reduction in system compressibility. Asymptotic values of porewater pressure within the clay are in good agreement with externally applied backpressure values. Inspection of data provides no evidence for the development of hydraulic thresholds within the clay, subject to the boundary conditions of this test geometry. Analysis of the stress data demonstrates significant hysteresis between ascending and descending porewater pressure histories. The amount of hysteresis appears to be linked to the magnitude of the backpressure applied to the specimen

  1. Sensitivity of total stress to changes in externally applied water pressure in KBS-3 buffer bentonite

    International Nuclear Information System (INIS)

    Harrington, J.F.; Birchall, D.J.

    2007-04-01

    In the current Swedish repository design concept, composite copper and steel canisters containing spent nuclear fuel will be placed in large diameter disposal boreholes drilled into the floor of the repository tunnels. The space around each canister will be filled with pre-compacted bentonite which over time will draw in the surrounding ground water and swell, closing up any construction joints. However, for the purposes of performance assessment, it is necessary to consider the effect of glacial loading of a future repository and its impact on the mechanical behaviour of the bentonite, in particular, the sensitivity of total stress to changes in porewater pressure (backpressure). Two experimental histories have been undertaken using a custom-designed constant volume and radial flow (CVRF) apparatus. In both tests backpressure was varied in a number of incremental and decremental cycles while total stress, porewater pressure and volumetric flow rate were continuously monitored. The swelling pressure of the buffer clay at dry densities of 1.8 Mg/m 3 and 1.61 Mg/m 3 was determined to be around 5.5 MPa and 7.2 MPa respectively. For initial ascending porewater pressure histories the average proportionality factor α ranged from 0.86 and 0.92. Data exhibited a general trend of increasing α with increasing backpressure. In test Mx80-11 this was supported by analysis of the water inflow data which indicated a reduction in system compressibility. Asymptotic values of porewater pressure within the clay are in good agreement with externally applied backpressure values. Inspection of data provides no evidence for the development of hydraulic thresholds within the clay, subject to the boundary conditions of this test geometry. Analysis of the stress data demonstrates significant hysteresis between ascending and descending porewater pressure histories. The amount of hysteresis appears to be linked to the magnitude of the backpressure applied to the specimen, suggesting some

  2. [Characterization of kale (Brassica oberacea var acephala) under thallium stress by in situ attenuated total reflection FTIR].

    Science.gov (United States)

    Yao, Yan; Zhang, Ping; Wang, Zhen-Chun; Chen, Yong-Heng

    2009-01-01

    The experiment was designed based on consumption of carbon dioxide through the photosynthesis of Brassica oberacea var acephala leaf, and the photosynthesis of kale leaf under thallium stress was investigated by in situ attenuated total reflection FTIR (in situ ATR-FTIR). The ATR-FTIR showed that the absorption peaks of leaves had no obvious difference between plants growing in thallium stress soil and plants growing in non-thallium pollution soil, and the strong peaks at 3,380 cm(-1) could be assigned to the absorption of water, carbohydrate, protein or amide; the strong peaks at 2,916 and 2,850 cm(-1) assigned to the absorption of carbohydrate or aliphatic compound; the peaks at 1,640 cm(-1) assigned to the absorption of water. However, as detected by the in situ ATR-FTIR, the double peaks (negative peaks) at 2,360 and 2,340 cm(-1) that are assigned to the absorption of CO2 appeared and became high gradually. It was showed that kale was carrying photosynthesis. At the same time, the carbon dioxide consumption speed of leaf under thallium stress was obviously larger than that of the blank It was expressed that photosynthesis under thallium stress was stronger than the blank All these represented that kale had certain tolerance to the heavy metal thallium. Meanwhile, the carbon dioxide consumption of grown-up leaf was more than that of young leaf whether or not under thallium stress. It was also indicated that the intensity of photosynthesis in grown-up leaf is higher than that in young leaf.

  3. Development of total systems of piping stress analysis and evaluation: ISAPPS

    International Nuclear Information System (INIS)

    Oki, Teizaburo; Koyanagi, Ryoichi; Fukuda, Masanao

    1978-01-01

    IHI has developed the systems of piping stress analysis and evaluation: ISAPPS (IHI Stress Analysis Program for Piping Systems), which are further described in this paper. In addition, the results of structural analysis and heat transfer analysis were confirmed. An example of stress evaluation in accordance with the modified ASME Code Sec. III is shown. ISAPPS consists of the following seven parts, and is designed for easy adoption of other programs by making modifications. 1. Piping design oriented language programs 2. Structural analysis programs 3. Isometric plotting programs 4. Multi-file dumping program 5. Load combination program 6. Heat transfer program 7. Stress evaluation programs As one of the examples of structural analysis programs, IHI make use of the modified SAP IV developed by the University of California. Evaluations of stresses are performed in accordance with: 1. ASME Boiler and Pressure Vessel Code, Sec. III Class 1, 2 and 3 2. ANSI Code, B31.1 and B31.3 3. MITI (Ministry of International Trade and Industry ) Code ISAPPS is very useful for design of nuclear and chemical pipings and so on. (author)

  4. The Importance of Lower Mantle Structure to Plate Stresses and Plate Motions

    Science.gov (United States)

    Holt, W. E.; Wang, X.; Ghosh, A.

    2016-12-01

    Plate motions and plate stresses are widely assumed as the surface expression of mantle convection. The generation of plate tectonics from mantle convection has been studied for many years. Lithospheric thickening (or ridge push) and slab pull forces are commonly accepted as the major driving forces for the plate motions. However, the importance of the lower mantle to plate stresses and plate motions remains less clear. Here, we use the joint modeling of lithosphere and mantle dynamics approach of Wang et al. (2015) to compute the tractions originating from deeper mantle convection and follow the method of Ghosh et al. (2013) to calculate gravitational potential energy per unit area (GPE) based on Crust 1.0 (Laske et al., 2013). Absolute values of deviatoric stresses are determined by the body force distributions (GPE gradients and traction magnitudes applied at the base of the lithosphere). We use the same relative viscosity model that Ghosh et al. (2013) used, and we solve for one single adjustable scaling factor that multiplies the entire relative viscosity field to provide absolute values of viscosity throughout the lithosphere. This distribution of absolute values of lithosphere viscosities defines the magnitudes of surface motions. In this procedure, the dynamic model first satisfies the internal constraint of no-net-rotation of motions. The model viscosity field is then scaled by the single factor until we achieve a root mean square (RMS) minimum between computed surface motions and the kinematic no-net-rotation (NNR) model of Kreemer et al. (2006). We compute plate stresses and plate motions from recently published global tomography models (over 70 based on Wang et al., 2015). We find that RMS misfits are significantly reduced when details of lower mantle structure from the latest tomography models are added to models that contain only upper and mid-mantle density distributions. One of the key reasons is that active upwelling from the Large Low Shear

  5. Evaluation of nitrogen status and total chlorophyll in longkong (Aglaia dookkoo Griff. leaves under water stress using a chlorophyll meter

    Directory of Open Access Journals (Sweden)

    Sdoodee, S.

    2005-07-01

    Full Text Available A chlorophyll meter (SPAD-502 was used to assess nitrogen status and total chlorophyll in longkong leaves, leaves from twelve of 10-year-old trees grown in the experimental plot at Prince of Songkla University, Songkhla province. The relationship between SPAD-502 meter reading and nitrogen status and total chlorophyll content analyzed in the laboratory was evaluated during 8 months (May-December 2003. It was found that the trend of the relationships in each month was similar. There was no significant differenceamong regression linears of all months. The data of 8 months showed that SPAD-reading and nitrogen content, and SPAD-reading and total chlorophyll content were related in a positive manner. They were Y = 0.19X+10.10, r = 0.76** (n = 240, and Y = 0.43X-7.89, r = 0.79** (n = 400, respectively. The SPAD-502 was then used to assess total nitrogen and total chlorophyll content during imposed water stress. Fifteen 4-yearold plants were grown in pots (each pot containing 50 kg soil volume. The experiment was arranged in acompletely randomized design with 3 treatments: (1 daily watering (2 once watering on day 7 (3 no watering with 5 replications during 14 days of the experimental period. Measurements showed a continuous decrease of SPAD-reading in the treatment of no watering. On day 14, a significant difference of SPAD- reading values between the treatment of daily watering and no watering was found. Then, the values of nitrogen content and total chlorophyll were assessed by using the linear regression equations. From the result, it is suggested that the measurement by chlorophyll meter is a rapid technique for the evaluation of total chlorophyll and nitrogen status in longkong leaves during water stress.

  6. Quantitative monitoring of sucrose, reducing sugar and total sugar dynamics for phenotyping of water-deficit stress tolerance in rice through spectroscopy and chemometrics

    Science.gov (United States)

    Das, Bappa; Sahoo, Rabi N.; Pargal, Sourabh; Krishna, Gopal; Verma, Rakesh; Chinnusamy, Viswanathan; Sehgal, Vinay K.; Gupta, Vinod K.; Dash, Sushanta K.; Swain, Padmini

    2018-03-01

    In the present investigation, the changes in sucrose, reducing and total sugar content due to water-deficit stress in rice leaves were modeled using visible, near infrared (VNIR) and shortwave infrared (SWIR) spectroscopy. The objectives of the study were to identify the best vegetation indices and suitable multivariate technique based on precise analysis of hyperspectral data (350 to 2500 nm) and sucrose, reducing sugar and total sugar content measured at different stress levels from 16 different rice genotypes. Spectral data analysis was done to identify suitable spectral indices and models for sucrose estimation. Novel spectral indices in near infrared (NIR) range viz. ratio spectral index (RSI) and normalised difference spectral indices (NDSI) sensitive to sucrose, reducing sugar and total sugar content were identified which were subsequently calibrated and validated. The RSI and NDSI models had R2 values of 0.65, 0.71 and 0.67; RPD values of 1.68, 1.95 and 1.66 for sucrose, reducing sugar and total sugar, respectively for validation dataset. Different multivariate spectral models such as artificial neural network (ANN), multivariate adaptive regression splines (MARS), multiple linear regression (MLR), partial least square regression (PLSR), random forest regression (RFR) and support vector machine regression (SVMR) were also evaluated. The best performing multivariate models for sucrose, reducing sugars and total sugars were found to be, MARS, ANN and MARS, respectively with respect to RPD values of 2.08, 2.44, and 1.93. Results indicated that VNIR and SWIR spectroscopy combined with multivariate calibration can be used as a reliable alternative to conventional methods for measurement of sucrose, reducing sugars and total sugars of rice under water-deficit stress as this technique is fast, economic, and noninvasive.

  7. Micro-mechanical investigation of the effect of fine content on mechanical behavior of gap graded granular materials using DEM

    Directory of Open Access Journals (Sweden)

    Taha Habib

    2017-01-01

    Full Text Available In this paper, we present a micro-mechanical study of the effect of fine content on the behavior of gap graded granular samples by using numerical simulations performed with the Discrete Element Method. Different samples with fine content varied from 0% to 30% are simulated. The role of fine content in reinforcing the granular skeleton and in supporting the external deviatoric stress is then brought into the light.

  8. The stress response and anesthetic potency of unilateral spinal anesthesia for total Hip Replacement in geriatric patients.

    Science.gov (United States)

    Zhu, Li; Tian, Chun; Li, Min; Peng, Ming-Qing; Ma, Kun-Long; Wang, Zhong-Lin; Ding, Jia-Hui; Cai, Yi

    2014-11-01

    Recently, some scholars suggested that it is important to keep a stablehemodynamic state and prevent the stress responses in geriatric patients undergoing total hip replacement (THR). We conducted this randomized prospective study to observe anesthetic potency of unilateral spinal anesthesia and stress response to it in geriatric patients during THR. We compared the effect of unilateral spinal and bilateral spinal on inhibition of stress response through measuring Norepinephrine (NE), epinephrine (E) and cortisol (CORT). Plasma concentrations of NE, E and CORT were determined in blood samples using ELISA (enzyme-linked immunosorbent assays) at three time points: To (prior to anesthesia) T1 (at the time point of skin closure), T2 (twenty-four hours after the operation). Sixty patients were randomly divided into two groups: group A (unilateral spinal anesthesia) and group B (conventional bilateral spinal anesthesia). 7.5tymg of hypobaric bupivacaine were injected into subarachnoid cavity at group A and 12mg hypobaric bupivacaine were given at group B. The onset time of sensory and motor block, loss of pinprick sensation, degree of motor block, regression of sensory and motor blocks and hemodynamic changes were also recorded. These data were used to evaluate anesthetic potency of spinal anesthesia. The results of this experiment show that unilateral spinal anesthesia can provide restriction of sensory and motor block, minimize the incidence of hypotension and prevent the stress responses undergoing THR. It is optimal anesthesia procedure for geriatric patients by rapid subarachnoid injection of small doses of bupivacaine.

  9. Resuspended contaminated sediments cause sublethal stress to oysters: A biomarker differentiates total suspended solids and contaminant effects.

    Science.gov (United States)

    Edge, Katelyn J; Dafforn, Katherine A; Simpson, Stuart L; Ringwood, Amy H; Johnston, Emma L

    2015-06-01

    Resuspended contaminated sediments represent an important route of contaminant exposure for aquatic organisms. During resuspension events, filter-feeding organisms are exposed to contaminants, in both the dissolved form (at the gills) and the particulate form (in the digestive system). In addition, these organisms must manage the physical stress associated with an increase in total suspended solids (TSS). To date, few studies have experimentally compared the contributions to biological stress of contaminated and clean suspended solids. The authors mixed field-collected sediments (cellular biomarkers (lysosomal membrane stability, lipid peroxidation, and glutathione) were measured to evaluate sublethal toxicity. Lysosomal membrane stability was the most sensitive biomarker for distinguishing effects from resuspended contaminated sediments, as increasing amounts of contaminated TSS increased lysosomal membrane destabilization. The authors' results illustrate the importance of considering contaminant exposures from resuspended sediments when assessing the toxicity of contaminants to aquatic organisms. © 2015 SETAC.

  10. Complete stress tensor determination by microearthquake analysis

    Science.gov (United States)

    Slunga, R.

    2010-12-01

    Jones 1984 found that half of the shallow strike-slip EQ in California had at least one M>2 foreshock. By the Gutenberg law this means at least 3-20 M>0 (low b-value 0.4-0.8). deformations within the crust. This was confirmed by observations in Iceland after 1990 when anew seismic network in Iceland operated by IMO started. Like the Parkfield project in California the SIL network in Iceland was established in an area predicted (Einarsson et al 1981, Stefansson and Halldorsson 1988) to be struck by major EQs within decades of years. The area of main interest have a detection threshold of M=0. A physical approach was chosen to the earthquake warning problem (Stefansson et al 1993) and therefore all microearthquakes were analyzed for FPS by the spectral amplitude method (Slunga 1981). As the shear slip is caused by the in situ stress it is logical to investigate what bounds the FPS puts on the stress tensor. McKenzie 1969 assumed that the earthquake takes place in a crust containing only one fracture, the fault plane. He found that in s uch a case only very weak constraints could be put on the stress. This was widely accepted t o be valid also for microearthquakes in the real crust and lead to methods (Angelier 1978, G ephart and Forsythe 1984 etc) to put four constraints on the stress tensor by assuming that the same stress tensor is causing the slip on four or more different fractures. Another and more realistic approach is to assume that the crust have frequent fractures with almost all orientations. In such a case one can rely on Coulomb's failure criterion for isotropic mat erial (gives four constraints) instead of the weaker Bolt's criterion (giving only one const raint). One obvious fifth constraint is to require the vertical stress to equal the lithosta tic pressure. A sixth constraint is achieved by requiring that the deviatoric elastic energy is minimized. The water pressure is also needed for the fourth constraint by Coulomb (CFS=0 ). It can be related to

  11. Recent approaches to the total synthesis of phytoprostanes, isoprostanes and neuroprostanes as important products of lipid oxidative stress and biomarkers of disease

    Czech Academy of Sciences Publication Activity Database

    Jahn, Emanuela; Durand, T.; Galano, J. M.; Jahn, Ullrich

    2014-01-01

    Roč. 108, č. 4 (2014), s. 301-319 ISSN 0009-2770 Institutional support: RVO:61388963 Keywords : lipids * oxidative stress * phytoprostanes * isoprostanes * neuroprostanes * total synthesis Subject RIV: CC - Organic Chemistry Impact factor: 0.272, year: 2014

  12. Experimental study on the thermo-mechanical behaviour of stiff clay under non-isotropic stress state

    International Nuclear Information System (INIS)

    Tang, Anh Minh; Cui, Yu-Jun; Li, Xiang-Ling

    2012-01-01

    conditions. Hueckel et al. (2009) cited some few laboratory tests where undrained heating was performed on clays under non-isotropic stress state. Some other tests can be found in Monfared et al. (2012). Both works show that heating under non-isotropic stress state and undrained conditions can induce thermal failure in saturated clays. In the present work, the thermo-mechanical behaviour of clays is also investigated but drained conditions were applied. The soil studied was Boom clay, taken form the Mol underground research laboratory operated by EURIDICE in Belgium. Beside common triaxial compression tests performed at various temperatures (ranging from 20 C to 80 C), specific tests were performed under the similar thermo-mechanical loading path as in the near field of the repository. One of these tests is detailed here. A temperature-controlled high-pressure triaxial cell was used in this studied. After the installation of the soil specimen in the cell, the soil was re-saturated under isotropic in situ stress state (2.5 MPa) to reach similar in situ conditions. At the end of the saturation phase (t = 500 h), the confining pressure (p) was 3.5 MPa, the back pressure (u) was 1.0 MPa, and the effective isotropic stress (p-u) was 2.5 MPa. From this state, the deviatoric stress was increased slowly (with a rate of 0.3 kPa/min) to reach 1.6 MPa. This value was then kept constant until the end of the test (figure 1b). This shearing induce axial strain and volumetric strain which stabilised at 2.30% and 0.23% respectively (at t = 1700 h). From this state, the soil temperature, which was kept constant at 25 C from the beginning of the test, was increased step-by-step to 40 C, 60 C, and 80 C. The results show that heating increased the axial strain respectively to 3.10%, 4.10%, and 5.73%. The volumetric behaviour of soil during heating did not show a clear trend, the volumetric strain decreased to 0% at the end of 40 C stage, reached 0.89% at the end of 60 C stage, and reached up to

  13. Improving stress shielding following total hip arthroplasty by using a femoral stem made of β type Ti-33.6Nb-4Sn with a Young's modulus gradation

    NARCIS (Netherlands)

    Yamako, Go; Janssen, Dennis; Hanada, Shuji; Anijs, Thomas; Ochiai, Kiyohide; Totoribe, Koji; Chosa, Etsuo; Verdonschot, Nico

    2017-01-01

    Stress shielding-related bone loss occurs after total hip arthroplasty because the stiffness of metallic implants differs from that of the host femur. Although reducing stem stiffness can ameliorate the bone resorption, it increases stress at the bone–implant interface and can inhibit fixation. To

  14. Ipsilateral stress fracture of the proximal fibula after total knee arthroplasty in a patient with severe valgus knee deformity on a background of Rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Hirokazu Takai

    Full Text Available Introduction: Previous studies have reported a lower extremity stress fracture after total knee arthroplasty (TKA. However, a fibular fracture after TKA is quite rare. We report a case of proximal fibula fracture after TKA in a patient with rheumatoid arthritis (RA. Presentation of case: A 45 year old woman with RA had severe knee and foot pain with an antalgic gait disturbance. There was a significant joint deformity in many of lower limb joints. Interval bilateral TKAs were performed two weeks apart. Right TKA was performed using a constraint-type prosthesis, through lateral parapatellar approach. Left TKA was performed using a posterior-stabilized (PS prosthesis through the more commonly employed, medial parapatellar approach. Seven weeks after the right TKA, the patient was found to have an atraumatic proximal fibular fracture. The fracture went on to heal conservatively. Discussion: The fracture was considered to have occurred after the TKA. The callus appeared eleven weeks after the TKA. The factors that contributed to the fracture were thought to be overload of the fragile bone secondarily to disuse osteopaenia, RA or potentially the significant valgus malalignment correction. The surgical approach, the implant or implantation or the persisting joint deformity, were thought to be contributing factors to the aetiology of the stress fracture. The resultant change in clinical outcome/course is outlined in this case report. Conclusion: A stress fracture of the proximal fibula has the potential in the aetiology of may cause other stress fractures, joint other instability, and/or malalignment of the total lower extremity. Keywords: Stress fracture, Insufficiency fracture, Total knee arthroplasty, Fibula fracture, Valgus deformity, Rheumatoid arthritis

  15. Inversion of calcite twin data for paleostress (1) : improved Etchecopar technique tested on numerically-generated and natural data

    Science.gov (United States)

    Parlangeau, Camille; Lacombe, Olivier; Daniel, Jean-Marc; Schueller, Sylvie

    2015-04-01

    Inversion of calcite twin data are known to be a powerful tool to reconstruct the past-state of stress in carbonate rocks of the crust, especially in fold-and-thrust belts and sedimentary basins. This is of key importance to constrain results of geomechanical modelling. Without proposing a new inversion scheme, this contribution reports some recent improvements of the most efficient stress inversion technique to date (Etchecopar, 1984) that allows to reconstruct the 5 parameters of the deviatoric paleostress tensors (principal stress orientations and differential stress magnitudes) from monophase and polyphase twin data sets. The improvements consist in the search of the possible tensors that account for the twin data (twinned and untwinned planes) and the aid to the user to define the best stress tensor solution, among others. We perform a systematic exploration of an hypersphere in 4 dimensions by varying different parameters, Euler's angles and the stress ratio. We first record all tensors with a minimum penalization function accounting for 20% of the twinned planes. We then define clusters of tensors following a dissimilarity criterion based on the stress distance between the 4 parameters of the reduced stress tensors and a degree of disjunction of the related sets of twinned planes. The percentage of twinned data to be explained by each tensor is then progressively increased and tested using the standard Etchecopar procedure until the best solution that explains the maximum number of twinned planes and the whole set of untwinned planes is reached. This new inversion procedure is tested on monophase and polyphase numerically-generated as well as natural calcite twin data in order to more accurately define the ability of the technique to separate more or less similar deviatoric stress tensors applied in sequence on the samples, to test the impact of strain hardening through the change of the critical resolved shear stress for twinning as well as to evaluate the

  16. Total workload, work stress and perceived symptoms in Swedish male and female white-collar employees.

    Science.gov (United States)

    Krantz, Gunilla; Berntsson, Leeni; Lundberg, Ulf

    2005-04-01

    The aim of this study was to analyse how paid work, unpaid household tasks, child care, work-child care interactions and perceived work stress are associated with reported symptoms in male and female white-collar employees. A questionnaire was mailed to 1300 men and 1300 women belonging to the white-collar sector, with at least 35 hours of regular employment a week and a participant age of between 32 and 58 years. It contained items relating to total workload (hours spent on paid work, unpaid household tasks and childcare), subjective indices for work stress and symptoms. The response rate was 65% (743 women; 595 men). Gender difference in symptom prevalence was tested by analyses of variance. Odds ratios were used to estimate the bivariate associations between work-related variables and symptom prevalence. A multivariate analysis estimated the effect of paid and unpaid work interaction, work-childcare interplay and possible synergy. The frequency and severity of symptoms was higher in women than in men (P women's health was determined by the interaction between conditions at work and household duties (OR 2.09; 1.06-4.14), whereas men responded more selectively to long working hours, i.e. >50 h/week (OR 1.61; 1.02-2.54). However, childcare (women.

  17. X-Ray Microdiffraction as a Probe to Reveal Flux Divergences in Interconnects

    Science.gov (United States)

    Spolenak, R.; Tamura, N.; Patel, J. R.

    2006-02-01

    Most reliability issues in interconnect systems occur at a local scale and many of them include the local build-up of stresses. Typical failure mechanisms are electromigration and stress voiding in interconnect lines and fatigue in surface acoustic wave devices. Thus a local probe is required for the investigation of these phenomena. In this paper the application of the Laue microdiffraction technique to investigate flux divergences in interconnect systems will be described. The deviatoric strain tensor of single grains can be correlated with the local microstructure, orientation and defect density. Especially the latter led to recent results about the correlation of stress build-up and orientation in Cu lines and electromigration-induced grain rotation in Cu and Al lines.

  18. Microdiffraction: X-rays as a probe to reveal flux divergences ininterconnects

    Energy Technology Data Exchange (ETDEWEB)

    Spolenak, R.; Tamura, N.; Patel, J.R.

    2006-01-01

    Most reliability issues in interconnect systems occur at a local scale and many of them include the local build-up of stresses. Typical failure mechanisms are electromigration and stress voiding in interconnect lines and fatigue in surface acoustic wave devices. Thus a local probe is required for the investigation of these phenomena. In this paper the application of the Laue microdiffraction technique to investigate flux divergences in interconnect systems will be described. The deviatoric strain tensor of single grains can be correlated with the local microstructure, orientation and defect density. Especially the latter led to recent results about the correlation of stress build-up and orientation in Cu lines and electromigration-induced grain rotation in Cu and Al lines.

  19. Numerical model of total artificial heart hemodynamics and the effect of its size on stress accumulation.

    Science.gov (United States)

    Marom, Gil; Chiu, Wei-Che; Slepian, Marvin J; Bluestein, Danny

    2014-01-01

    The total artificial heart (TAH) is a bi-ventricular mechanical circulatory support device that replaces the heart in patients with end-stage congestive heart failure. The device acts as blood pump via pneumatic activation of diaphragms altering the volume of the ventricular chambers. Flow in and out of the ventricles is controlled by mechanical heart valves. The aim of this study is to evaluate the flow regime in the TAH and to estimate the thrombogenic potential during systole. Toward that goal, three numerical models of TAHs of differing sizes, that include the deforming diaphragm and the blood flow from the left chamber to the aorta, are introduced. A multiphase model with injection of platelet particles is employed to calculate their trajectories. The shear stress accumulation in the three models are calculated along the platelets trajectories and their probability density functions, which represent the `thrombogenic footprint' of the device are compared. The calculated flow regime successfully captures the mitral regurgitation and the flows that open and close the aortic valve during systole. Physiological velocity magnitudes are found in all three models, with higher velocities and increased stress accumulation predicted for smaller devices.

  20. Glacial Erosion Driven by Seasonal Shifts in Meltwater Drainage

    Science.gov (United States)

    Ugelvig, S. V.; Egholm, D. L.

    2017-12-01

    Subglacial erosion processes, like abrasion and quarrying, have been studied for decades. While models for abrasion clearly points to sliding speed as a primary control on abrasion rates, quarrying rates are thought to be governed by more complex combinations of sliding speed, effective pressure, bedrock slope and short-term water pressure fluctuations. Early models for quarrying focused on the deviatoric stress needed for growth of small isolated cracks in otherwise homogeneous intact bedrock. The rate-limiting factor for quarrying was thus the subcritical crack growth. Later studies have included effects of pre-existing fractures in the bedrock that weaken the rock. Here the strength distribution in the rock is based on the assumption that larger rock bodies have lower strength, because they have a higher probability of containing a weak fracture. However, this approach has been hampered by the assumption of steady-state cavity configuration. Here we attempt to combine previous model efforts in a model that tracks the temporal evolution of cavities while including a statistical treatment of bedrock strength. Using a two-dimensional finite-difference model, we simulate the spatial and temporal evolution of the hydrological system at the base of a glacier, while simultaneously computing rates of abrasion and quarrying. Cavity lengths and channel cross-sections evolve through time, which allow us to study how temporal shifts in ice-bed contact area and deviatoric stress influence quarrying rates over the course of a year. Furthermore, we use the temporal evolution of contact area between ice and bed to predict basal sliding speed and scale abrasion rates. Our results suggest that ice-bed contact area is a key variable in controlling sliding speed and rates of glacial erosion on seasonal time scales, where the subglacial drainage system reorganizes to accommodate the variations in surface melt rates. However, on diurnal timescales cavities and channels cannot adjust

  1. Glacial rebound and crustal stress in Finland

    International Nuclear Information System (INIS)

    Lambeck, K.; Purcell, A.

    2003-11-01

    rebound and sea-level change within the Baltic Basin. (iv) The magnitude and orientation of the regional stress field in the crust since the time of the last glaciation, including the present-day residual stress field. The current models have reached a state where realistic regional stress patterns can be predicted that provide the background data for developing high-resolution local numerical models. This study is confined to the regional stress field only. We use as a measure of the significance of the incremental stress the change in Fault Stability Margin (FSM) resulting from the changes in ice (and ocean) load with time. While ice is present, the crust is stabilized except outside the area of loading, but when the ice retreats the crust becomes less stable and faults that are close to failure may be reactivated. For much of central Finland the deviatoric FSM reach their maximum values at about 10 ka BP but the magnitudes relax with time and at present they represent about 20% of their original values. Thus any failure within the crust triggered by glacial loading and unloading will have occurred preferentially when the region first became ice-free and the potential for reactivating faults today by this process must be considered as negligibly. (orig.)

  2. Conduit Stability and Collapse in Explosive Volcanic Eruptions: Coupling Conduit Flow and Failure Models

    Science.gov (United States)

    Mullet, B.; Segall, P.

    2017-12-01

    Explosive volcanic eruptions can exhibit abrupt changes in physical behavior. In the most extreme cases, high rates of mass discharge are interspaced by dramatic drops in activity and periods of quiescence. Simple models predict exponential decay in magma chamber pressure, leading to a gradual tapering of eruptive flux. Abrupt changes in eruptive flux therefore indicate that relief of chamber pressure cannot be the only control of the evolution of such eruptions. We present a simplified physics-based model of conduit flow during an explosive volcanic eruption that attempts to predict stress-induced conduit collapse linked to co-eruptive pressure loss. The model couples a simple two phase (gas-melt) 1-D conduit solution of the continuity and momentum equations with a Mohr-Coulomb failure condition for the conduit wall rock. First order models of volatile exsolution (i.e. phase mass transfer) and fragmentation are incorporated. The interphase interaction force changes dramatically between flow regimes, so smoothing of this force is critical for realistic results. Reductions in the interphase force lead to significant relative phase velocities, highlighting the deficiency of homogenous flow models. Lateral gas loss through conduit walls is incorporated using a membrane-diffusion model with depth dependent wall rock permeability. Rapid eruptive flux results in a decrease of chamber and conduit pressure, which leads to a critical deviatoric stress condition at the conduit wall. Analogous stress distributions have been analyzed for wellbores, where much work has been directed at determining conditions that lead to wellbore failure using Mohr-Coulomb failure theory. We extend this framework to cylindrical volcanic conduits, where large deviatoric stresses can develop co-eruptively leading to multiple distinct failure regimes depending on principal stress orientations. These failure regimes are categorized and possible implications for conduit flow are discussed, including

  3. Structure and Calibration of Constitutive Equations for Granular Soils

    Directory of Open Access Journals (Sweden)

    Sawicki Andrzej

    2015-02-01

    Full Text Available The form of incremental constitutive equations for granular soils is discussed for the triaxial configuration. The classical elasto-plastic approach and the semi-empirical model are discussed on the basis of constitutive relations determined directly from experimental data. First, the general structure of elasto-plastic constitutive equations is presented. Then, the structure of semiempirical constitutive equations is described, and a method of calibrating the model is presented. This calibration method is based on a single experiment, performed in the triaxial apparatus, which also involves a partial verification of the model, on an atypical stress path. The model is shown to give reasonable predictions. An important feature of the semi-empirical incremental model is the definition of loading and unloading, which is different from that assumed in elasto-plasticity. This definition distinguishes between spherical and deviatoric loading/unloading. The definition of deviatoric loading/unloading has been subject to some criticism. It was therefore discussed and clarified in this paper on the basis of the experiment presented.

  4. Modelling of the fuel mechanical behavior. From creep laws to internal variable models

    International Nuclear Information System (INIS)

    Leclercq, S.

    1997-01-01

    Creep laws are nowadays commonly used to simulate the fuel rod response to the solicitations it faces during its life. These laws are sufficient for describing the base operating conditions (where only creep appears), but they have to be improved for power ramp conditions (where hardening and relaxation appear). The main objective of the present paper was to clearly exhibit the important role of the porosity on the fuel mechanical behavior. It has been shown that viscoplastic properties are activated by the evolution of the porosity. A general framework has been developed, in agreement with the principles of thermodynamics of irreversible processes. The major result of the present model concerns the fact that the viscoplastic strain is non-deviatoric, due to the porosity growth. The purely deviatoric part of the non-linear strain is taken as the Lemaitre law, but any other classical equation may be used. As concerns the hydrostatic part, it is derived from simple assumptions. The coupling between the volume fraction of porosity and the mechanical stress field is introduced into the dissipation term. (author)

  5. Modelling of the fuel mechanical behavior. From creep laws to internal variable models

    Energy Technology Data Exchange (ETDEWEB)

    Leclercq, S. [Electricite de France (EDF), 77 - Moret sur Loing (France)

    1997-12-31

    Creep laws are nowadays commonly used to simulate the fuel rod response to the solicitations it faces during its life. These laws are sufficient for describing the base operating conditions (where only creep appears), but they have to be improved for power ramp conditions (where hardening and relaxation appear). The main objective of the present paper was to clearly exhibit the important role of the porosity on the fuel mechanical behavior. It has been shown that viscoplastic properties are activated by the evolution of the porosity. A general framework has been developed, in agreement with the principles of thermodynamics of irreversible processes. The major result of the present model concerns the fact that the viscoplastic strain is non-deviatoric, due to the porosity growth. The purely deviatoric part of the non-linear strain is taken as the Lemaitre law, but any other classical equation may be used. As concerns the hydrostatic part, it is derived from simple assumptions. The coupling between the volume fraction of porosity and the mechanical stress field is introduced into the dissipation term. (author) 6 refs.

  6. High stresses stored in fault zones: example of the Nojima fault (Japan)

    Science.gov (United States)

    Boullier, Anne-Marie; Robach, Odile; Ildefonse, Benoît; Barou, Fabrice; Mainprice, David; Ohtani, Tomoyuki; Fujimoto, Koichiro

    2018-04-01

    During the last decade pulverized rocks have been described on outcrops along large active faults and attributed to damage related to a propagating seismic rupture front. Questions remain concerning the maximal lateral distance from the fault plane and maximal depth for dynamic damage to be imprinted in rocks. In order to document these questions, a representative core sample of granodiorite located 51.3 m from the Nojima fault (Japan) that was drilled after the Hyogo-ken Nanbu (Kobe) earthquake is studied by using electron backscattered diffraction (EBSD) and high-resolution X-ray Laue microdiffraction. Although located outside of the Nojima damage fault zone and macroscopically undeformed, the sample shows pervasive microfractures and local fragmentation. These features are attributed to the first stage of seismic activity along the Nojima fault characterized by laumontite as the main sealing mineral. EBSD mapping was used in order to characterize the crystallographic orientation and deformation microstructures in the sample, and X-ray microdiffraction was used to measure elastic strain and residual stresses on each point of the mapped quartz grain. Both methods give consistent results on the crystallographic orientation and show small and short wavelength misorientations associated with laumontite-sealed microfractures and alignments of tiny fluid inclusions. Deformation microstructures in quartz are symptomatic of the semi-brittle faulting regime, in which low-temperature brittle plastic deformation and stress-driven dissolution-deposition processes occur conjointly. This deformation occurred at a 3.7-11.1 km depth interval as indicated by the laumontite stability domain. Residual stresses are calculated from deviatoric elastic strain tensor measured using X-ray Laue microdiffraction using the Hooke's law. The modal value of the von Mises stress distribution is at 100 MPa and the mean at 141 MPa. Such stress values are comparable to the peak strength of a

  7. High stresses stored in fault zones: example of the Nojima fault (Japan

    Directory of Open Access Journals (Sweden)

    A.-M. Boullier

    2018-04-01

    Full Text Available During the last decade pulverized rocks have been described on outcrops along large active faults and attributed to damage related to a propagating seismic rupture front. Questions remain concerning the maximal lateral distance from the fault plane and maximal depth for dynamic damage to be imprinted in rocks. In order to document these questions, a representative core sample of granodiorite located 51.3 m from the Nojima fault (Japan that was drilled after the Hyogo-ken Nanbu (Kobe earthquake is studied by using electron backscattered diffraction (EBSD and high-resolution X-ray Laue microdiffraction. Although located outside of the Nojima damage fault zone and macroscopically undeformed, the sample shows pervasive microfractures and local fragmentation. These features are attributed to the first stage of seismic activity along the Nojima fault characterized by laumontite as the main sealing mineral. EBSD mapping was used in order to characterize the crystallographic orientation and deformation microstructures in the sample, and X-ray microdiffraction was used to measure elastic strain and residual stresses on each point of the mapped quartz grain. Both methods give consistent results on the crystallographic orientation and show small and short wavelength misorientations associated with laumontite-sealed microfractures and alignments of tiny fluid inclusions. Deformation microstructures in quartz are symptomatic of the semi-brittle faulting regime, in which low-temperature brittle plastic deformation and stress-driven dissolution-deposition processes occur conjointly. This deformation occurred at a 3.7–11.1 km depth interval as indicated by the laumontite stability domain. Residual stresses are calculated from deviatoric elastic strain tensor measured using X-ray Laue microdiffraction using the Hooke's law. The modal value of the von Mises stress distribution is at 100 MPa and the mean at 141 MPa. Such stress values are comparable to

  8. Elastoplastic cup model for cement-based materials

    Directory of Open Access Journals (Sweden)

    Yan Zhang

    2010-03-01

    Full Text Available Based on experimental data obtained from triaxial tests and a hydrostatic test, a cup model was formulated. Two plastic mechanisms, respectively a deviatoric shearing and a pore collapse, are taken into account. This model also considers the influence of confining pressure. In this paper, the calibration of the model is detailed and numerical simulations of the main mechanical behavior of cement paste over a large range of stress are described, showing good agreement with experimental results. The case study shows that this cup model has extensive applicability for cement-based materials and other quasi-brittle and high-porosity materials in a complex stress state.

  9. On the Magnitude and Orientation of Stress during Shock Metamorphism: Understanding Peak Ring Formation by Combining Observations and Models.

    Science.gov (United States)

    Rae, A.; Poelchau, M.; Collins, G. S.; Timms, N.; Cavosie, A. J.; Lofi, J.; Salge, T.; Riller, U. P.; Ferrière, L.; Grieve, R. A. F.; Osinski, G.; Morgan, J. V.; Expedition 364 Science Party, I. I.

    2017-12-01

    . Our results quantitatively describe the deviatoric stress conditions of rocks in shock, which are consistent with observations of shock deformation. Our integrated analysis provides further support for the dynamic collapse model of peak-ring formation, and places dynamic constraints on the conditions of peak-ring formation.

  10. Total Water Management - Report

    Science.gov (United States)

    There is a growing need for urban water managers to take a more holistic view of their water resource systems as population growth, urbanization, and current operations put different stresses on the environment and urban infrastructure. Total Water Management (TWM) is an approac...

  11. Mining-induced fault reactivation associated with the main conveyor belt roadway and safety of the Barapukuria Coal Mine in Bangladesh: Constraints from BEM simulations

    Energy Technology Data Exchange (ETDEWEB)

    Islam, Md. Rafiqul; Shinjo, Ryuichi [Department of Physics and Earth Sciences, University of the Ryukyus, Okinawa, 903-0213 (Japan)

    2009-09-01

    Fault reactivation during underground mining is a critical problem in coal mines worldwide. This paper investigates the mining-induced reactivation of faults associated with the main conveyor belt roadway (CBR) of the Barapukuria Coal Mine in Bangladesh. The stress characteristics and deformation around the faults were investigated by boundary element method (BEM) numerical modeling. The model consists of a simple geometry with two faults (Fb and Fb1) near the CBR and the surrounding rock strata. A Mohr-Coulomb failure criterion with bulk rock properties is applied to analyze the stability and safety around the fault zones, as well as for the entire mining operation. The simulation results illustrate that the mining-induced redistribution of stresses causes significant deformation within and around the two faults. The horizontal and vertical stresses influence the faults, and higher stresses are concentrated near the ends of the two faults. Higher vertical tensional stress is prominent at the upper end of fault Fb. High deviatoric stress values that concentrated at the ends of faults Fb and Fb1 indicate the tendency towards block failure around the fault zones. The deviatoric stress patterns imply that the reinforcement strength to support the roof of the roadway should be greater than 55 MPa along the fault core zone, and should be more than 20 MPa adjacent to the damage zone of the fault. Failure trajectories that extend towards the roof and left side of fault Fb indicate that mining-induced reactivation of faults is not sufficient to generate water inflow into the mine. However, if movement of strata occurs along the fault planes due to regional earthquakes, and if the faults intersect the overlying Lower Dupi Tila aquiclude, then liquefaction could occur along the fault zones and enhance water inflow into the mine. The study also reveals that the hydraulic gradient and the general direction of groundwater flow are almost at right angles with the trends of

  12. Work-Home Interference, Perceived Total Workload, and the Risk of Future Sickness Absence Due to Stress-Related Mental Diagnoses Among Women and Men: a Prospective Twin Study.

    Science.gov (United States)

    Svedberg, Pia; Mather, Lisa; Bergström, Gunnar; Lindfors, Petra; Blom, Victoria

    2018-02-01

    Work-home interference has been proposed as an important explanation for sickness absence (SA). Previous studies show mixed results, have not accounted for familial factors (genetics and shared everyday environment), or investigated diagnosis specific SA. The aim was to study whether work-home interference and perceived total workload predict SA due to stress-related mental diagnoses, or SA due to other mental diagnoses, among women and men, when adjusting for various confounders and familial factors. This study included 11,916 twins, 19-47 years (49% women). Data on work-to-home and home-to-work conflicts, perceived total workload, and relevant confounders were derived from a 2005 survey, and national register data on SA spells until 2013 were obtained. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated. Discordant twin pair design was applied to adjust for familial factors. Each one unit increase in work-to-home and home-to-work conflicts, and perceived total workload was associated with higher odds for SA due to stress-related mental diagnoses and to SA due to other mental diagnoses among women, when adjusting for sociodemographic factors (ORs 1.15-1.31). Including health or familial factors, no associations remained. For men, each one unit increase in work-to-home conflicts was associated with higher odds for SA due to stress-related diagnoses (ORs 1.23-1.35), independently of confounders. Work-to-home conflict was independently associated with future SA due to stress-related diagnoses among men only. Health- and work-related factors seem to be important confounders when researching work-home interference, perceived total workload, and SA. Not including such confounders involves risking drawing incorrect conclusions. Further studies are needed to confirm sex differences and whether genetic factors are important for the associations studied.

  13. Physiological Indices of Stress Prior to and Following Total Knee Arthroplasty Predict the Occurrence of Severe Post-Operative Pain.

    Science.gov (United States)

    Cremeans-Smith, Julie K; Greene, Kenneth; Delahanty, Douglas L

    2016-05-01

    The severe pain and disability associated with osteoarthritis often motivate individuals to undergo arthroplastic surgery. However, a significant number of surgical patients continue to experience pain following surgery. Prior research has implicated both the hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) in the sensitization of pain receptors and chronic pain conditions. This study uses a prospective, observational, cohort design to examine whether physiological stress responses before and after surgery could predict post-operative pain severity. Participants included 110 patients undergoing total knee arthroplasty. Physiological indices of stress included the measurement of catecholamine and cortisol levels in 15-hour urine samples collected prior to and 1 month following surgery, as well as in-hospital heart rate and blood pressure (before and after surgery), which were abstracted from medical records. Patients completed the pain subscale of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) [Bellamy et al., J Orthop Rheumatol 1: , 95 (1988)] 2.5 weeks prior to surgery and at a 3-month follow-up. Contrary to expectations, lower stress hormone levels at baseline were related to more severe post-operative pain. Data at later time points, however, supported our hypothesis: cardiovascular tone shortly before surgery and urinary levels of epinephrine 1 month following surgery were positively related to pain severity 3 months later. Results suggest that the occurrence of post-operative pain can be predicted on the basis of stress physiology prior to and following arthroplastic surgery. © 2015 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. Acute effect of sorghum flour-containing pasta on plasma total polyphenols, antioxidant capacity and oxidative stress markers in healthy subjects: A randomised controlled trial.

    Science.gov (United States)

    Khan, Imran; Yousif, Adel M; Johnson, Stuart K; Gamlath, Shirani

    2015-06-01

    It has been previously reported that pasta containing wholegrain sorghum flour exhibits high content of polyphenols and antioxidant capacity and hence might enhance antioxidant status and reduce markers of oxidative stress in vivo; however no clinical studies have yet been reported. Therefore, the present study assessed the effect of pasta containing red or white wholegrain sorghum flour on plasma total polyphenols, antioxidant capacity and oxidative stress markers in humans. The study was registered with the Australian New Zealand Clinical Trials Registry (ACTRN: 12612000324819). In a randomised crossover design, healthy subjects (n = 20) consumed three test meals of control pasta (CP), 30% red sorghum pasta (RSP) or 30% white sorghum pasta (WSP), 1-2 wk apart. The test meals were consumed as breakfast after an overnight fast. Blood samples were obtained at fasting and 2 h after consumption and analysed for total polyphenols, antioxidant capacity, superoxide dismutase (SOD) activity, protein carbonyl and 8-isoprostanes. Compared to baseline, the 2 h post-prandial levels following the RSP meal of plasma polyphenols, antioxidant capacity and SOD activity were significantly (P pasta containing red wholegrain sorghum flour enhanced antioxidant status and improved markers of oxidative stress in healthy subjects. Copyright © 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  15. Wheat cultivars selected for high Fv /Fm under heat stress maintain high photosynthesis, total chlorophyll, stomatal conductance, transpiration and dry matter.

    Science.gov (United States)

    Sharma, Dew Kumari; Andersen, Sven Bode; Ottosen, Carl-Otto; Rosenqvist, Eva

    2015-02-01

    The chlorophyll fluorescence parameter Fv /Fm reflects the maximum quantum efficiency of photosystem II (PSII) photochemistry and has been widely used for early stress detection in plants. Previously, we have used a three-tiered approach of phenotyping by Fv /Fm to identify naturally existing genetic variation for tolerance to severe heat stress (3 days at 40°C in controlled conditions) in wheat (Triticum aestivum L.). Here we investigated the performance of the previously selected cultivars (high and low group based on Fv /Fm value) in terms of growth and photosynthetic traits under moderate heat stress (1 week at 36/30°C day/night temperature in greenhouse) closer to natural heat waves in North-Western Europe. Dry matter accumulation after 7 days of heat stress was positively correlated to Fv /Fm . The high Fv /Fm group maintained significantly higher total chlorophyll and net photosynthetic rate (PN ) than the low group, accompanied by higher stomatal conductance (gs ), transpiration rate (E) and evaporative cooling of the leaf (ΔT). The difference in PN between the groups was not caused by differences in PSII capacity or gs as the variation in Fv /Fm and intracellular CO2 (Ci ) was non-significant under the given heat stress. This study validated that our three-tiered approach of phenotyping by Fv /Fm performed under increasing severity of heat was successful in identifying wheat cultivars differing in photosynthesis under moderate and agronomically more relevant heat stress. The identified cultivars may serve as a valuable resource for further studies to understand the physiological mechanisms underlying the genetic variability in heat sensitivity of photosynthesis. © 2014 Scandinavian Plant Physiology Society.

  16. Evaluation of constitutive models for crushed salt

    International Nuclear Information System (INIS)

    Callahan, G.D.; Loken, M.C.; Hurtado, L.D.; Hansen, F.D.

    1996-01-01

    Three constitutive models are recommended as candidates for describing the deformation of crushed salt. These models are generalized to three-dimensional states of stress to include the effects of mean and deviatoric stress and modified to include effects of temperature, grain size, and moisture content. A database including hydrostatic consolidation and shear consolidation tests conducted on Waste Isolation Pilot Plant (WIPP) and southeastern New Mexico salt is used to determine material parameters for the models. To evaluate the capability of the models, parameter values obtained from fitting the complete database are used to predict the individual tests. Finite element calculations of a WIPP shaft with emplaced crushed salt demonstrate the model predictions

  17. Possible superlattice formation in high-temperature treated carbonaceous MgB2 at elevated pressure

    International Nuclear Information System (INIS)

    Tschauner, Oliver; Errandonea, Daniel; Serghiou, George

    2006-01-01

    We report indications of a phase transition in carbonaceous MgB 2 above 9 GPa at 300 K after stress relaxation by laser heating. The transition was detected using Raman spectroscopy and X-ray diffraction. The observed changes are consistent with a second-order structural transition involving a doubling of the unit cell along c and a reduction of the boron site symmetry. Moreover, the Raman spectra suggest a reduction in electron-phonon coupling in the slightly modified MgB 2 structure consistent with the previously proposed topological transition in MgB 2 . However, further attributes including deviatoric stress, lattice defects, and compositional variation may play an important role in the observed phenomena

  18. 77 FR 62396 - Annual Company-Run Stress Test Requirements for Banking Organizations With Total Consolidated...

    Science.gov (United States)

    2012-10-12

    ... minimum risk-based capital requirements.\\3\\ Stress testing is one tool that helps both bank supervisors... the FDIC and the OCC to help to ensure that the company-run stress testing regulations are consistent... purposes of the annual company-run stress tests so that the same set of scenarios can be used to conduct...

  19. Significance of Serum Total Oxidant/Antioxidant Status in Patients with Colorectal Cancer.

    Directory of Open Access Journals (Sweden)

    Rong Wu

    Full Text Available Oxidative stress is involved in a variety of diseases. Prospective studies investigating the relationship between oxidative stress biomarkers and the status and development of colorectal cancer (CRC are scarce; previous studies have failed to establish a relationship between the serum total oxidant/antioxidant status and CRC. Therefore, we compared the total serum oxidant/antioxidant levels of CRC patients and healthy subjects, and analyzed their clinical significance in the CRC. Fasting blood samples from 132 CRC patients and 64 healthy subjects were collected. Oxidative stress parameters, including total oxidant status (TOS and total antioxidant status (TAS, were measured, and the oxidative stress index (OSI was calculated. The TOS and OSI levels increased significantly (P0.05.However, the levels of TOS, TAS, and OSI were significantly different between patients with no metastasis and those with metastases to two organs (P<0.05 Finally, the parameters are affected by smoking and drinking, and subsequent research should be conducted excluding the relevant influencing factors.

  20. Canadian dental students' perceptions of stress.

    Science.gov (United States)

    Muirhead, Vanessa; Locker, David

    2007-05-01

    In this paper, we report the results of a survey on dental student stress carried out in April 2005. A questionnaire was used to collect data from 171 students (62% response rate). Identified stressors were academic, clinic-related, social and financial. "Examination and grades" produced the most academic stress, and inconsistent feedback from instructors created the most clinic-related stress. Students found that having a dual role--wife or husband and dental student--was the most burdensome social stressor. Approximately 60% of students reported marital problems and stress associated with "relations with members of the opposite sex." Survey results showed that students who expected a high graduating debt had higher total and academic stress scores. Total stress was not related to age, gender or marital status. Students living with parents during term time had significantly higher total stress scores than students living in other arrangements. Students residing with parents also had significantly higher debts on entry to dental school. Students with more predental education had (non-significantly) lower stress scores but also had higher student debts. Undergraduate subject major (biological science or non-science) had no bearing on reported stress. This study highlights the negative effects of student debt, the necessity for staff training and the need for further studies exploring relations among stress, psychological well-being and academic performance.

  1. Faulting mechanisms and stress regime at the European HDR site of Soultz-sous-Forets, France

    International Nuclear Information System (INIS)

    Cuenot, Nicolas; Charlety, Jean; Haessler, Henri; Dorbath, Louis

    2006-01-01

    The state of stress and its implications for shear on fault planes during fluid injection are crucial issues for the HDR (Hot Dry Rock) or EGS (Enhanced or Engineered Geothermal System) concept. This is especially true for hydraulic stimulation experiments, aimed at enhancing the connectivity of a borehole to the natural fracture network, since they tend to induce the shearing of fractures, which is controlled by the local stress regime. During the 2000 and 2003 stimulation tests at Soultz-sous-Forets, France, about 10,000 microearthquakes were located with a surface seismological network. Hundreds of double-couple (DC) focal mechanisms were automatically determined from first-motion polarities using the FPFIT program [Reasenberg, P.A., Oppenheimer, D., 1985. FPFIT, FPPLOT and FPPAGE: Fortran computer programs for calculating and displaying earthquake fault-plane solutions. US Geological Survey Open-File Report 85-739, 25 pp.]. The majority of these mechanisms indicate normal-faulting movement with a more or less pronounced strike-slip component. Some quasi-pure strike-slip events also occurred, especially in the deeper part of the stimulated rock volume, at more than 5 km depth. Although we found a double-couple solution for all events, we tried to observe and quantify the proportion of the non-double-couple (NDC) component in the seismic moment tensor for several microseisms from the 2003 data. The study shows that the NDC is higher for the events in the vicinity of the injection well than for the events far from the well. We used the method of Rivera and Cisternas [Rivera, L., Cisternas, A., 1990. Stress tensor and fault-plane solutions for a population of earthquakes. Bull. Seismol. Soc. Am. 80, 600-614.] to perform the inversion of the deviatoric part of the stress tensor from P-wave polarities. This method was applied to different datasets from the 2000 test, taken from the shallower and deeper parts of the stimulated region. The results show a stable

  2. Faulting mechanisms and stress regime at the European HDR site of Soultz-sous-Forets, France

    Energy Technology Data Exchange (ETDEWEB)

    Cuenot, Nicolas; Charlety, Jean; Haessler, Henri [Institut de Physique du Globe de Strasbourg, Ecole et Observatoire des Sciences de la Terre (IPGS-EOST), 5 rue Rene Descartes, 67084 Strasbourg Cedex (France); Dorbath, Louis [Institut de Physique du Globe de Strasbourg, Ecole et Observatoire des Sciences de la Terre (IPGS-EOST), 5 rue Rene Descartes, 67084 Strasbourg Cedex (France); Institut de Recherche pour le Developpement, Laboratoire des Mecanismes et Transferts en Geologie (IRD, LMTG), 14 Avenue Edouard Belin, 31400 Toulouse (France)

    2006-10-15

    The state of stress and its implications for shear on fault planes during fluid injection are crucial issues for the HDR (Hot Dry Rock) or EGS (Enhanced or Engineered Geothermal System) concept. This is especially true for hydraulic stimulation experiments, aimed at enhancing the connectivity of a borehole to the natural fracture network, since they tend to induce the shearing of fractures, which is controlled by the local stress regime. During the 2000 and 2003 stimulation tests at Soultz-sous-Forets, France, about 10,000 microearthquakes were located with a surface seismological network. Hundreds of double-couple (DC) focal mechanisms were automatically determined from first-motion polarities using the FPFIT program [Reasenberg, P.A., Oppenheimer, D., 1985. FPFIT, FPPLOT and FPPAGE: Fortran computer programs for calculating and displaying earthquake fault-plane solutions. US Geological Survey Open-File Report 85-739, 25 pp.]. The majority of these mechanisms indicate normal-faulting movement with a more or less pronounced strike-slip component. Some quasi-pure strike-slip events also occurred, especially in the deeper part of the stimulated rock volume, at more than 5 km depth. Although we found a double-couple solution for all events, we tried to observe and quantify the proportion of the non-double-couple (NDC) component in the seismic moment tensor for several microseisms from the 2003 data. The study shows that the NDC is higher for the events in the vicinity of the injection well than for the events far from the well. We used the method of Rivera and Cisternas [Rivera, L., Cisternas, A., 1990. Stress tensor and fault-plane solutions for a population of earthquakes. Bull. Seismol. Soc. Am. 80, 600-614.] to perform the inversion of the deviatoric part of the stress tensor from P-wave polarities. This method was applied to different datasets from the 2000 test, taken from the shallower and deeper parts of the stimulated region. The results show a stable

  3. Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohepatitis.

    Science.gov (United States)

    Horoz, Mehmet; Bolukbas, Cengiz; Bolukbas, Fusun F; Sabuncu, Tevfik; Aslan, Mehmet; Sarifakiogullari, Serpil; Gunaydin, Necla; Erel, Ozcan

    2005-11-11

    Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of nonalcoholic steatohepatitis. We aimed to investigate the total antioxidant response using a novel automated method in nonalcoholic steatohepatitis subjects. As a reciprocal measure, we also aimed to determine total peroxide level in the same plasma samples. Twenty-two subjects with biopsy proven nonalcoholic steatohepatitis and 22 healthy controls were enrolled. Total antioxidant response and total peroxide level measurements were done in all participants. The ratio percentage of total peroxide level to total antioxidant response was regarded as oxidative stress index. Total antioxidant response of subjects with nonalcoholic steatohepatitis was significantly lower than controls (p total peroxide level and mean oxidative stress index were higher (all p total peroxide level, total antioxidant response and oxidative stress index (p 0.05). Nonalcoholic steatohepatitis is associated with increased oxidant capacity, especially in the presence of liver fibrosis. The novel automated assay is a reliable and easily applicable method for total plasma antioxidant response measurement in nonalcoholic steatohepatitis.

  4. Orientation dependence of shock-induced twinning and substructures in a copper bicrystal

    International Nuclear Information System (INIS)

    Cao Fang; Beyerlein, Irene J.; Addessio, Francis L.; Sencer, Bulent H.; Trujillo, Carl P.; Cerreta, Ellen K.; Gray, George T. III

    2010-01-01

    Shock recovery experiments have been conducted to assess the role of shock stress and orientation dependence on substructure evolution and deformation twinning of a [1 0 0]/[011-bar] copper bicrystal. Transmission electron microscopy of the post-shock specimens revealed that well-defined dislocation cell structures developed in both grains and the average cell size decreased with increasing shock pressure from 5 to 10 GPa. Twinning occurred in the [1 0 0] grain, but not the [011-bar] grain, at the 10 GPa shock pressure. The stress and orientation dependence of incipient twinning can be predicted by the stress and orientation conditions required to dissociate slip dislocations into glissile twinning dislocations. The dynamic widths between the two partials are calculated considering the three-dimensional deviatoric stress state induced by the shock as calculated using plane-strain plate impact simulations and the relativistic and drag effects on dislocations moving at high speeds.

  5. Measures of total stress-induced blood pressure responses are associated with vascular damage.

    Science.gov (United States)

    Nazzaro, Pietro; Seccia, Teresa; Vulpis, Vito; Schirosi, Gabriella; Serio, Gabriella; Battista, Loredana; Pirrelli, Anna

    2005-09-01

    The role of cardiovascular reactivity to study hypertension, and the assessment methods, are still controversial. We aimed to verify the association of hypertension and vascular damage with several measures of cardiovascular response. We studied 40 patients with normal-high (132 +/- 1/87 +/- 1 mm Hg) blood pressure (Group 1) and 80 untreated hypertensive subjects. Postischemic forearm vascular resistance (mFVR) served to differentiate hypertensive subjects (142 +/- 2/92 +/- 1 mm Hg v 143 +/- 2/94 +/- 2 mm Hg, P = NS) with a lower (Group 2) and higher (Group 3) hemodynamic index of vascular damage (4.8 +/- .05 v 6.3 +/- .09, P blood pressure, heart rate, forearm blood flow, and vascular resistance. Reactivity measures included: a) change from baseline, b) residualized score, c) cumulative change from baseline and residualized score, and d) total reactivity as area-under-the-curve (AUC), including changes occurring during baseline and recovery phases. The AUC of systolic blood pressure, diastolic blood pressure, and mFVR progressively increased in the groups (P AUC of SBP, DBP, and forearm blood flow and resistance demonstrated the highest (P AUC of SBP (beta = 0.634) and forearm blood flow (beta = -0.337) were predictive (P blood pressure stress response, as AUC, including baseline and recovery phases, was significantly better associated with hypertension and vascular damage than the other reactivity measures studied.

  6. Total oxidant status, total antioxidant capacity and ischemia modified albumin levels in children with celiac disease.

    Science.gov (United States)

    Sayar, Ersin; Özdem, Sebahat; Uzun, Gülbahar; İşlek, Ali; Yılmaz, Aygen; Artan, Reha

    2015-01-01

    In our study, we aimed to investigate ischemia modified albumin (IMA) as an oxidative stress marker, as well as other oxidant and antioxidant markers that have not been evaluated in children with celiac disease. A total of 37 pediatric patients who were diagnosed with celiac disease (CD) and 29 healthy children were enrolled in this prospective study. We evaluated the IMA, total oxidant status, total antioxidant capacity, sulfhydryl, and advanced oxidation protein products in all of the subjects. We also compared the levels at the time of the diagnosis, and following a gluten-free diet (GFD) in the children with CD. While the IMA and the other oxidant marker levels were significantly higher in the patient group compared to the control group, the antioxidant marker levels were found to be significantly lower in the patient group, compared to the control group. We also determined that the tissue transglutaminase IgA showed a highly positive correlation, and that the IMA showed a moderately positive correlation with the Marsh-Oberhuber histopathological stage. Additionally, the IMA and other oxidant marker levels were significantly lower, while the antioxidant marker levels were significantly higher after the GFD, compared to the pre-diet period. We detected that oxidative stress played a role in the pathogenesis of CD, and that this could be evaluated using oxidative stress markers, which would regress after the GFD. We also detected that IMA is a marker that shows a correlation with the histopathological stage, and may be used in the diagnosis.

  7. The relationship between beginning teachers' stress causes, stress responses, teaching behaviour and attrition

    NARCIS (Netherlands)

    Harmsen, Ruth; Lorenz, Michelle; Maulana, Ridwan; van Veen, Klaas

    2018-01-01

    In this study, the relationships between beginning teachers’ perceived stress causes, stress responses, observed teaching behaviour and attrition is investigated employing structural equation modelling (SEM). A total of 143 BTs were surveyed using the Questionnaire on the Experience and Evaluation

  8. Oxidative stress in hepatitis C infected end-stage renal disease subjects.

    Science.gov (United States)

    Horoz, Mehmet; Bolukbas, Cengiz; Bolukbas, Filiz F; Aslan, Mehmet; Koylu, Ahmet O; Selek, Sahbettin; Erel, Ozcan

    2006-07-14

    Both uremia and hepatitis C infection is associated with increased oxidative stress. In the present study, we aimed to find out whether hepatitis C infection has any impact on oxidative stress in hemodialysis subjects. Sixteen hepatitis C (+) hemodialysis subjects, 24 hepatitis C negative hemodialysis subjects and 24 healthy subjects were included. Total antioxidant capacity, total peroxide level and oxidative stress index were determined in all subjects. Total antioxidant capacity was significantly higher in controls than hemodialysis subjects with or without hepatitis C infection (all p total peroxide level and oxidative stress index were significantly lower (all p total antioxidant capacity compared to hepatitis C (+) hemodialysis subjects (all p Total peroxide level and oxidative stress index was comparable between hemodialysis subjects with or without hepatitis C infection (p > 0.05/3). Oxidative stress is increased in both hepatitis C (+) and hepatitis C (-) hemodialysis subjects. However, hepatitis C infection seems to not cause any additional increase in oxidative stress in hemodialysis subjects and it may be partly due to protective effect of dialysis treatment on hepatitis C infection.

  9. Contralateral limb during total contact casting. A dynamic pressure and thermometric analysis.

    Science.gov (United States)

    Armstrong, D G; Liswood, P J; Todd, W F

    1995-12-01

    The authors draw attention to the importance of evaluation of the contralateral limb when treating unilateral sequelae secondary to distal symmetrical polyneuropathy. Plantar pressure measurements of the contralateral limb during total contact casting are reviewed. The results of thermometric evaluation before and after initiation of repetitive stress were reviewed. The results suggest that the patient walking in a total contact cast may experience a reduced focal pressure on the contralateral limb when compared with uncasted walking and three-point walking with crutches. Dermal thermometry may be a highly sensitive tool in evaluating even mild increases in repetitive stress. To explain this decrease in contralateral stress, the authors examine the features inherent to the total contact cast and propose the concept of proprioceptive stability.

  10. Financial stress spillovers in advanced economies

    NARCIS (Netherlands)

    Apostolakis, G.; Papadopoulos, A.

    2014-01-01

    Financial stress co-movements are positively associated with crisis periods. Dynamic conditional correlations increase during periods of high uncertainty. The US is the dominant transmitter of financial stress spillovers. The total stress spillover index explains 19.9% of the forecast error

  11. Mental Toughness in Competitive Tennis: Relationships with Resilience and Stress

    Directory of Open Access Journals (Sweden)

    Richard Gregory Cowden

    2016-03-01

    Full Text Available The present study investigated the relationships between mental toughness (MT, resilience, and stress among competitive South African tennis players. A total of 351 tennis players participating at various competitive standards completed the Sport Mental Toughness Questionnaire, the Resilience Scale for Adults, and a modified version of the Recovery-Stress Questionnaire for Athletes. The results indicated that total MT was positively associated with total resilience (r = .59, but negatively associated with total stress (r = -.44. The resilience subscales of perception of self, perception of future, social competence, and social resources, but not family cohesion, significantly predicted total MT (R2 = .35. Both total resilience and total MT significantly predicted total stress (R2 = .21. Based on the findings, interrelations between MT and resilience are explored, implications outlined, and additional research is suggested to ascertain the contextual relevance and outcomes associated with each construct in sport.

  12. Mental Toughness in Competitive Tennis: Relationships with Resilience and Stress.

    Science.gov (United States)

    Cowden, Richard G; Meyer-Weitz, Anna; Oppong Asante, Kwaku

    2016-01-01

    The present study investigated the relationships between mental toughness (MT), resilience, and stress among competitive South African tennis players. A total of 351 tennis players participating at various competitive standards completed the Sports Mental Toughness Questionnaire, the Resilience Scale for Adults, and a modified version of the Recovery-Stress Questionnaire for Athletes. The results indicated that total MT was positively associated with total resilience (r = 0.59), but negatively associated with total stress (r = -0.44). The resilience subscales of perception of self, perception of future, social competence, and social resources, but not family cohesion, significantly predicted total MT (R (2) = 0.35). Both total resilience and total MT significantly predicted total stress (R (2) = 0.21). Based on the findings, interrelations between MT and resilience are explored, implications outlined, and additional research is suggested to ascertain the contextual relevance and outcomes associated with each construct in sport.

  13. Associations between circadian and stress response cortisol in children.

    Science.gov (United States)

    Simons, Sterre S H; Cillessen, Antonius H N; de Weerth, Carolina

    2017-01-01

    Hypothalamic-pituitary-adrenal (HPA) axis functioning is characterized by the baseline production of cortisol following a circadian rhythm, as well as by the superimposed production of cortisol in response to a stressor. However, it is relatively unknown whether the basal cortisol circadian rhythm is associated with the cortisol stress response in children. Since alterations in cortisol stress responses have been associated with mental and physical health, this study investigated whether the cortisol circadian rhythm is associated with cortisol stress responses in 6-year-old children. To this end, 149 normally developing children (M age  = 6.09 years; 70 girls) participated in an innovative social evaluative stress test that effectively provoked increases in cortisol. To determine the cortisol stress response, six cortisol saliva samples were collected and two cortisol stress response indices were calculated: total stress cortisol and cortisol stress reactivity. To determine children's cortisol circadian rhythm eight cortisol circadian samples were collected during two days. Total diurnal cortisol and diurnal cortisol decline scores were calculated as indices of the cortisol circadian rhythm. Hierarchical regression analyses indicated that higher total diurnal cortisol as well as a smaller diurnal cortisol decline, were both uniquely associated with higher total stress cortisol. No associations were found between the cortisol circadian rhythm indices and cortisol stress reactivity. Possible explanations for the patterns found are links with children's self-regulatory capacities and parenting quality.

  14. Strengthening and stress relaxation of Opalinus Clay

    International Nuclear Information System (INIS)

    Schulze, Otto

    2010-01-01

    undisturbed far-field for the long lasting periods of geological times. Consequently, demands on concepts for backfilling and closure of a repository in a clay-stone formation as well as model calculations for safety analyses generally do not take into account convergence by viscous deformation, which would result from stress re-distribution at underground openings. Although there is some doubt, whether Opalinus Clay is creeping at all, some very long lasting laboratory tests were performed on this item in the author's laboratory. A nearly linear dependence of the long-term creep rate on the deviatoric stress was found. In recent work, the technique of stress-relaxation was used. For this, strengthening by strain rate controlled deformation was stopped, i.e. the strain was kept constant for a long time, and the relaxation of the stress was measured. In course of this technique, the deformability which may result from artefacts is ruled out as far as possible by compaction and strengthening. Then, the stress relaxation - if any - will be maintained by true long-term deformation processes which should be active and responsible for any convergence in an at least only partly backfilled mine. In this contribution, the results of the laboratory work and their discussion will be presented. (authors)

  15. Association Between Maternal Serum Total Oxidant Status Total Antioxidant Status and Preterm Labor: A Prospective - Controlled Clinical Study

    OpenAIRE

    Hakan Kalaycı; Mete Gürol Uğur; Ebru Öztürk; Özcan Balat; Özcan Erel

    2011-01-01

    OBJECTIVE: To measure the levels of individual antioxidant components of pregnants with preterm labor to evaluate their total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI). STUDY DESIGN: Prospectively-controlled 31 pregnants with a diagnosis of preterm labor (group Ι) and 32 controls (group ΙΙ) were evaluated for demographic data, general and obstetrical physical examination, obstetrical sonography, and routine laboratory tests. TAS, TOS and OSI leve...

  16. Effect of cup inclination on predicted contact stress-induced volumetric wear in total hip replacement.

    Science.gov (United States)

    Rijavec, B; Košak, R; Daniel, M; Kralj-Iglič, V; Dolinar, D

    2015-01-01

    In order to increase the lifetime of the total hip endoprosthesis, it is necessary to understand mechanisms leading to its failure. In this work, we address volumetric wear of the artificial cup, in particular the effect of its inclination with respect to the vertical. Volumetric wear was calculated by using mathematical models for resultant hip force, contact stress and penetration of the prosthesis head into the cup. Relevance of the dependence of volumetric wear on inclination of the cup (its abduction angle ϑA) was assessed by the results of 95 hips with implanted endoprosthesis. Geometrical parameters obtained from standard antero-posterior radiographs were taken as input data. Volumetric wear decreases with increasing cup abduction angle ϑA. The correlation within the population of 95 hips was statistically significant (P = 0.006). Large cup abduction angle minimises predicted volumetric wear but may increase the risk for dislocation of the artificial head from the cup in the one-legged stance. Cup abduction angle and direction of the resultant hip force may compensate each other to achieve optimal position of the cup with respect to wear and dislocation in the one-legged stance for a particular patient.

  17. Greater physiological and behavioral effects of interrupted stress pattern compared to daily restraint stress in rats.

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    Full Text Available Repeated stress can trigger a range of psychiatric disorders, including anxiety. The propensity to develop abnormal behaviors after repeated stress is related to the severity, frequency and number of stressors. However, the pattern of stress exposure may contribute to the impact of stress. In addition, the anxiogenic nature of repeated stress exposure can be moderated by the degree of coping that occurs, and can be reflected in homotypic habituation to the repeated stress. However, expectations are not clear when a pattern of stress presentation is utilized that diminishes habituation. The purpose of these experiments is to test whether interrupted stress exposure decreases homotypic habituation and leads to greater effects on anxiety-like behavior in adult male rats. We found that repeated interrupted restraint stress resulted in less overall homotypic habituation compared to repeated daily restraint stress. This was demonstrated by greater production of fecal boli and greater corticosterone response to restraint. Furthermore, interrupted restraint stress resulted in a lower body weight and greater adrenal gland weight than daily restraint stress, and greater anxiety-like behavior in the elevated plus maze. Control experiments demonstrated that these effects of the interrupted pattern could not be explained by differences in the total number of stress exposures, differences in the total number of days that the stress periods encompased, nor could it be explained as a result of only the stress exposures after an interruption from stress. These experiments demonstrate that the pattern of stress exposure is a significant determinant of the effects of repeated stress, and that interrupted stress exposure that decreases habituation can have larger effects than a greater number of daily stress exposures. Differences in the pattern of stress exposure are therefore an important factor to consider when predicting the severity of the effects of repeated

  18. Mapping of QTLs for Germination Characteristics under Non-stress and Drought Stress in Rice

    Directory of Open Access Journals (Sweden)

    Zahra MARDANI

    2013-11-01

    Full Text Available Identification of genetic factors controlling traits associated with seed germination under drought stress conditions, leads to identification and development of drought tolerant varieties. Present study by using a population of F2:4 derived from a cross between a drought tolerant variety, Gharib (indica and a drought sensitive variety, Sepidroud (indica, is to identify and compare QTLs associated with germination traits under drought stress and non-stress conditions. Through QTL analysis, using composite interval mapping, regarding traits such as germination rate (GR, germination percentage (GP, radicle length (RL, plumule length (PL, coleorhiza length (COL and coleoptile length (CL, totally 13 QTLs were detected under pole drought stress (−8 MPa poly ethylene glycol 6000 and 9 QTLs under non-stress conditions. Of the QTLs identified under non-stress conditions, QTLs associated with COL (qCOL-5 and GR (qGR-1 explained 21.28% and 19.73% of the total phenotypic variations, respectively. Under drought stress conditions, QTLs associated with COL (qCOL-3 and PL (qPL-5 explained 18.34% and 18.22% of the total phenotypic variations, respectively. A few drought-tolerance-related QTLs identified in previous studies are near the QTLs detected in this study, and several QTLs in this study are novel alleles. The major QTLs like qGR-1, qGP-4, qRL-12 and qCL-4 identified in both conditions for traits GR, GP, RL and CL, respectively, should be considered as the important and stable trait-controlling QTLs in rice seed germination. Those major or minor QTLs could be used to significantly improve drought tolerance by marker-assisted selection in rice.

  19. Stress: Concepts and applications

    International Nuclear Information System (INIS)

    Nielsen, O.H.; Martin, R.M.

    1984-01-01

    The stress theorem determines the stress from the electronic ground state of any quantum system with arbitrary strains and atomic displacements. We derive this theorem in reciprocal space, within the local-density-functional approximation. The evaluation of stress, force and total energy permits, among other things, the determination of complete stress-strain relations including all microscopic internal strains. We describe results of ab-initio calculations for Si, Ge, and GaAs, giving the equilibrium lattice constant, all linear elastic constants c ij and the internal strain parameter ζ. (orig.)

  20. Rate dependent inelastic behavior of polycrystalline solids using a dislocation model

    International Nuclear Information System (INIS)

    Werne, R.W.; Kelly, J.M.

    1980-01-01

    A rate dependent theory of polycrystalline plasticity is presented in which the solid is modeled as an isotropic continuum with internal variables. The rate of plastic deformation is shown to be a function of the deviatoric portion of the Cauchy stress tensor as well as two scalar internal variables. The scalar internal variables, which are the dislocation density and mobile fraction, are governed by rate equations which reflect the evolution of microstructural processes. The model has been incorporated into a two dimensional finite element code and several example multidimensional problems are presented which exhibit the rate dependence of the material model

  1. Deformation-driven diffusion and plastic flow in amorphous granular pillars.

    Science.gov (United States)

    Li, Wenbin; Rieser, Jennifer M; Liu, Andrea J; Durian, Douglas J; Li, Ju

    2015-06-01

    We report a combined experimental and simulation study of deformation-induced diffusion in compacted quasi-two-dimensional amorphous granular pillars, in which thermal fluctuations play a negligible role. The pillars, consisting of bidisperse cylindrical acetal plastic particles standing upright on a substrate, are deformed uniaxially and quasistatically by a rigid bar moving at a constant speed. The plastic flow and particle rearrangements in the pillars are characterized by computing the best-fit affine transformation strain and nonaffine displacement associated with each particle between two stages of deformation. The nonaffine displacement exhibits exponential crossover from ballistic to diffusive behavior with respect to the cumulative deviatoric strain, indicating that in athermal granular packings, the cumulative deviatoric strain plays the role of time in thermal systems and drives effective particle diffusion. We further study the size-dependent deformation of the granular pillars by simulation, and find that different-sized pillars follow self-similar shape evolution during deformation. In addition, the yield stress of the pillars increases linearly with pillar size. Formation of transient shear lines in the pillars during deformation becomes more evident as pillar size increases. The width of these elementary shear bands is about twice the diameter of a particle, and does not vary with pillar size.

  2. Mine-by experiment committee report phase 1: excavation response summary and implications

    International Nuclear Information System (INIS)

    Martin, C.D.; Kaiser, P.K.

    1996-05-01

    The first phase of the Mine-by Experiment, i.e., excavation of a 3.5-m-diameter tunnel, was carried out at the 420 Level of the Underground Research Laboratory to investigate rock mass damage and progressive failure around a circular opening in brittle unfractitred Lac du Bonnet granite. The tunnel was excavated without explosives, and state-of-the-art instrumentation comprising both geomechanical and geophysical instruments was used to monitor the failure process. The experiment showed that rock mass damage begins once the deviatoric stress (0'1 - 0'3) near the advancing face of the tunnel exceeds a critical level. Crack propagation can lead to progressive failure around the tunnel; however, it is limited to a region, referred to as the excavation damaged zone, of less than one tunnel radius. Within the damaged zone, stabbing (a typical form of brittle failure) began at stress levels equivalent to about 50% of the short-term laboratory unconfined compressive strength. This reduction in strength between laboratory and in situ conditions occurs because the in situ loading path is far more complex than the monotonic loading path used to test laboratory samples. There is no evidence to suggest that the stabbing failure process would extend beyond the depth of damage defined by the deviatoric stress criterion. The stabbing process stops when the tunnel face has advanced sufficiently (approximately 2 tunnel diameters) such that the rock mass is no longer subjected to excavation-induced stress changes. The strength of the rock mass in the damaged zone must be back-calculated from in situ tests, because the loading path cannot be duplicated readily in the laboratory. Thus, the back-calculated damaged strength must be used to evaluate the stability of the excavation. Sealing systems to reduce the permeability in the axial direction of a tunnel must be keyed into the rock mass beyond the radial extent of the damaged zone. The shape of the seals must be designed so as to

  3. A Membrane Model from Implicit Elasticity Theory

    Science.gov (United States)

    Freed, A. D.; Liao, J.; Einstein, D. R.

    2014-01-01

    A Fungean solid is derived for membranous materials as a body defined by isotropic response functions whose mathematical structure is that of a Hookean solid where the elastic constants are replaced by functions of state derived from an implicit, thermodynamic, internal-energy function. The theory utilizes Biot’s (1939) definitions for stress and strain that, in 1-dimension, are the stress/strain measures adopted by Fung (1967) when he postulated what is now known as Fung’s law. Our Fungean membrane model is parameterized against a biaxial data set acquired from a porcine pleural membrane subjected to three, sequential, proportional, planar extensions. These data support an isotropic/deviatoric split in the stress and strain-rate hypothesized by our theory. These data also demonstrate that the material response is highly non-linear but, otherwise, mechanically isotropic. These data are described reasonably well by our otherwise simple, four-parameter, material model. PMID:24282079

  4. Single-shot full strain tensor determination with microbeam X-ray Laue diffraction and a two-dimensional energy-dispersive detector.

    Science.gov (United States)

    Abboud, A; Kirchlechner, C; Keckes, J; Conka Nurdan, T; Send, S; Micha, J S; Ulrich, O; Hartmann, R; Strüder, L; Pietsch, U

    2017-06-01

    The full strain and stress tensor determination in a triaxially stressed single crystal using X-ray diffraction requires a series of lattice spacing measurements at different crystal orientations. This can be achieved using a tunable X-ray source. This article reports on a novel experimental procedure for single-shot full strain tensor determination using polychromatic synchrotron radiation with an energy range from 5 to 23 keV. Microbeam X-ray Laue diffraction patterns were collected from a copper micro-bending beam along the central axis (centroid of the cross section). Taking advantage of a two-dimensional energy-dispersive X-ray detector (pnCCD), the position and energy of the collected Laue spots were measured for multiple positions on the sample, allowing the measurement of variations in the local microstructure. At the same time, both the deviatoric and hydrostatic components of the elastic strain and stress tensors were calculated.

  5. THE FIELD OF RECENT TECTONIC STRESSES IN CENTRAL AND SOUTH-EASTERN ASIA

    Directory of Open Access Journals (Sweden)

    Yu. L. Rebetsky

    2014-01-01

    Full Text Available  The publication presents results of the study aimed at reconstruction of recent crustal stresses for Central and South-Eastern Asia with application of the method of cataclastic analysis of displacements caused by ruptures, which was proposed by Yu.L. Rebetsky. Two sources of seismic data were referred to: (1 the catalog comprising data from publications covering the period from 1904 to 1992, and (2 the Global Centroid Moment Tensor (CMT Database of earthquake mechanisms (http://earthquake.usgs.gov/eqarchives/sopor, which covers the period from 1978 to 2010. The method of cataclastic analysis in its earliest version was applied in 1996 and 1997 when seismic data from the first catalog were analyzed, and it yielded only parameters of stress ellipsoids; the reconstructions were published in a Russian-Chinese journal (it does not exist now. In this paper, these reconstructions are presented in new graphical formats of GIS. Data from the Global CMT Database were analyzed by the method of cataclastic analysis in the new revision with application of its stages 1 and 2. Based on the calculations, orientations of axes of principal stresses, types of ellipsoids, correlations between spherical and deviatoric components of stress tensors, and reduced stresses were determined. The two sets of reconstructions are compared in this paper. The catalog of earthquake focal mechanisms for the period from 1904 to 1992 consolidated information provided by different authors, and thus focal data for many seismic events were highly inconsistent; therefore, the reliability of reconstructions based on such data seems to be lower than that on the basis the Global CMT Database for the period from 1978 to 2010. Some of the reconstructed stress tensor parameters are mapped. For the areas which data are given in the Global CMT Database and considered as more reliable, mapping is based on stress parameters calculated from such data. For the areas that are not covered by the

  6. Phasic and tonic stress-strain data obtained in intact intestinal segment in vitro

    DEFF Research Database (Denmark)

    Zhao, Jingbo; Liao, Donghua; Gregersen, Hans

    2008-01-01

    segments were isolated from ten Wistar rats and put into an organ bath containing 37 degrees C aerated Krebs solution. Ramp distension was done on active and passive intestinal segments at longitudinal stretch ratios of 0, 10, and 20%. Ramp pressures from 0 to 7.5 cmH(2)O were applied to the intestinal...... was defined as the total stress minus the passive stress. The total and passive circumferential stresses increased exponentially as a function of the strain. The amplitude of both the total and passive stress was biggest in the jejunum. The total circumferential stress decreased whereas the passive...

  7. Alumina strength degradation in the elastic regime

    International Nuclear Information System (INIS)

    Furnish, Michael D.; Chhabildas, Lalit C.

    1998-01-01

    Measurements of Kanel et al. [1991] have suggested that deviatoric stresses in glasses shocked to nearly the Hugoniot Elastic Limit (HEL) relax over a time span of microseconds after initial loading. 'Failure' (damage) waves have been inferred on the basis of these measurements using time-resolved manganin normal and transverse stress gauges. Additional experiments on glass by other researchers, using time-resolved gauges, high-speed photography and spall strength determinations have also lead to the same conclusions. In the present study we have conducted transmitted-wave experiments on high-quality Coors AD995 alumina shocked to roughly 5 and 7 GPa (just below or at the HEL). The material is subsequently reshocked to just above its elastic limit. Results of these experiments do show some evidence of strength degradation in the elastic regime

  8. Submicron X-ray diffraction

    International Nuclear Information System (INIS)

    MacDowell, Alastair; Celestre, Richard; Tamura, Nobumichi; Spolenak, Ralph; Valek, Bryan; Brown, Walter; Bravman, John; Padmore, Howard; Batterman, Boris; Patel, Jamshed

    2000-01-01

    At the Advanced Light Source in Berkeley the authors have instrumented a beam line that is devoted exclusively to x-ray micro diffraction problems. By micro diffraction they mean those classes of problems in Physics and Materials Science that require x-ray beam sizes in the sub-micron range. The instrument is for instance, capable of probing a sub-micron size volume inside micron sized aluminum metal grains buried under a silicon dioxide insulating layer. The resulting Laue pattern is collected on a large area CCD detector and automatically indexed to yield the grain orientation and deviatoric (distortional) strain tensor of this sub-micron volume. A four-crystal monochromator is then inserted into the beam, which allows monochromatic light to illuminate the same part of the sample. Measurement of diffracted photon energy allows for the determination of d spacings. The combination of white and monochromatic beam measurements allow for the determination of the total strain/stress tensor (6 components) inside each sub-micron sized illuminated volume of the sample

  9. Relationship between dilatancy, stresses and plastic dissipation in a granular material with rigid grains

    Science.gov (United States)

    Evesque, Pierre; Stefani, Christian

    1991-11-01

    By considering a drained cohesionless granular sample made up of rigid grains and submitted to a triaxial test, we derive an equation relating the dilatancy K, the deviatoric stress q and the confining pressure p to the energy losses D_plastic due to plastic yielding. We demonstrate that the system is contracting (K le 0) at q = 0, when q is increasing and that spontaneous uncontrolled yielding begins occurring when dilatancy K is maximum. We also demonstrate the existence of the characteristic state introduced by Luong and Habib and the existence of the critical state of Schofield and Wroth. Finally, we give a method to determine the plastic losses during a triaxial cell test using the experimental data. En utilisant un postulat de reproductibilité des essais triaxiaux et une relation liant l'énergie dissipée, la dilatance K et les contraintes imposées à un échantillon, on démontre qu'un matériau granulaire ne peut que se contracter après avoir subi une contrainte de confinement isotrope (i.e. q = 0), que la rupture spontanée a lieu après un maximum de dilatance, qu'il existe un état caractéristique (au sens de Luong et Habib) et qu'il existe un état “ critique ” (au sens de Schofield et Wroth). Nous donnons de plus une méthode pour estimer la dissipation-plastique durant un essai triaxial à partir des résultats expérimentaux.

  10. Stress at work: development of the Stress Perception Questionnaire of Rome (SPQR), an ad hoc questionnaire for multidimensional assessment of work related stress.

    Science.gov (United States)

    Cinti, M E; Cannavò, M; Fioravanti, M

    2017-01-01

    Stress is an emotional condition, mostly experienced as negative, initially identified and defined by Selye in the mid-thirties of the last Century. Since the first definition, stress concerns the adaptation pro- cess mostly related to environmental changes. An application of stress focuses on the evaluation of its interference on work conditions, and the scientific evidence on work related stress is very ample and rich. We are proposing a new ad hoc questionnaire for the multidimensional assessment of work related stress, called Stress Perception Question- naire of Rome (SPQR) composed of 50 items. The development of this questionnaire is based on a multi-step process: a) Identification of all the relevant topics to work related stress and areas in the scientific evidence and their transformation on specific contents of 60 tentative items; b) Exploratory factor analysis aimed to identify the best items (50) which could guarantee the maximum convergence on single scales (8), and the minimum redundancy between scales; c) Validation of the 8 scales' structure by a confirmatory factor analysis (fully achieved); d) Factor analysis for a second level factor resulting in a single factor identified as the questionnaire total score (Stress Score); d) Reliability analysis of the questionnaire total score and the single scale scores (at optimum level); e) Validation by external criteria of work related stress identified in the presence of personal violence episodes experienced by a group of health workers with different professional profiles and from two different hospitals in Rome. Our results show that the SPQR is a useful and sensitive tool for assessing the presence of emotional stress related problems identifiable in a work environment. The advantage of this questionnaire is that it allows for a multidimensional description of the different components of this problematic area besides its ability to quantify the overall stress level of those who have been administered

  11. Axial and transverse stress-strain characterization of the EU dipole high current density Nb{sub 3}Sn strand

    Energy Technology Data Exchange (ETDEWEB)

    Nijhuis, A; Ilyin, Y; Abbas, W [Faculty of Science and Technology, Low Temperature Division, University of Twente, PO Box 217, 7500 AE Enschede (Netherlands)], E-mail: a.nijhuis@tnw.utwente.nl

    2008-06-15

    We have measured the critical current (I{sub c}) of a high current density Nb{sub 3}Sn strand subjected to spatial periodic bending, periodic contact stress and uniaxial strain. The strand is destined for the cable-in-conduit conductors (CICC) of the European dipole (EDIPO) 12.5 T superconducting magnet test facility. The spatial periodic bending was applied on the strand, using the bending wavelengths from 5 to 10 mm with a peak bending strain of 1.5%, a periodic contact stress with a periodicity of 4.7 mm and a stress level exceeding 250 MPa. For the uniaxial strain characterization, the voltage-current characteristics were measured with an applied axial strain from -0.9% to +0.3%, with a magnetic field from 6 to 14 T, temperature from 4.2 to 10 K and currents up to almost 900 A. In addition the axial stiffness was determined by a tensile axial stress-strain test. The characterization of the strand is essential for understanding the behaviour of the strand under mainly axial thermal stress variation during cool down and transverse electromagnetic forces during charging, which is essential for the design of the CICC for the dipole magnet. The strand appears to be fully reversible in the compressive regime during the axial strain testing, while in the tensile regime, the behaviour is already irreversibly degraded when reaching the maximum in the critical current versus strain characteristic. The degradation is accentuated by an immediate decrease of the n value by a factor of 2. The parameters for the improved deviatoric strain description are derived from the I{sub c} data, giving the accuracy of the scaling with a standard deviation of 4 A, which is by far within the expected deviation for the large scale strand production of such a high J{sub c} strand. The I{sub c} versus the applied bending strain follows the low resistivity limit, indicative of full interfilament current transfer, while a strong decrease is observed at a peak bending strain of {approx}0

  12. Total oxidant/antioxidant status in jaundiced newborns before and after phototherapy.

    Science.gov (United States)

    Aycicek, Ali; Erel, Ozcan

    2007-01-01

    To assess the effect of phototherapy on serum oxidant and antioxidant status in hyperbilirubinemic full-term newborns. Thirty-four full-term infants from 3 to 10 days of age exposed to phototherapy were studied. The serum antioxidant status was assessed by measuring the total antioxidant capacity (TAC) and individual antioxidant components: vitamin C, uric acid, albumin, thiol contents and total bilirubin. The oxidant status was assessed by determining the total oxidant status (TOS), oxidative stress index (OSI) and individual oxidant components: malondialdehyde (MDA), and lipid hydroperoxide levels. Vitamin C, uric acid, total bilirubin and MDA concentration were significantly lower, whereas serum TOS, lipid hydroperoxide and OSI levels were significantly higher after phototherapy (p total bilirubin and MDA (r = 0.434, p = 0.001). Although the MDA level was reduced after phototherapy, phototherapy has a negative impact on numerous parts of the oxidant/antioxidant defense system in jaundiced full-term newborns, exposing them to potential oxidative stress.

  13. Adolescents' sleep in low-stress and high-stress (exam) times: a prospective quasi-experiment.

    Science.gov (United States)

    Dewald, Julia F; Meijer, Anne Marie; Oort, Frans J; Kerkhof, Gerard A; Bögels, Susan M

    2014-01-01

    This prospective quasi-experiment (N = 175; mean age = 15.14 years) investigates changes in adolescents' sleep from low-stress (regular school week) to high-stress times (exam week), and examines the (moderating) role of chronic sleep reduction, baseline stress, and gender. Sleep was monitored over three consecutive weeks using actigraphy. Adolescents' sleep was more fragmented during the high-stress time than during the low-stress time, meaning that individuals slept more restless during stressful times. However, sleep efficiency, total sleep time, and sleep onset latency remained stable throughout the three consecutive weeks. High chronic sleep reduction was related to later bedtimes, later sleep start times, later sleep end times, later getting up times, and more time spent in bed. Furthermore, low chronic sleep reduction and high baseline stress levels were related to more fragmented sleep during stressful times. This study shows that stressful times can have negative effects on adolescents' sleep fragmentation, especially for adolescents with low chronic sleep reduction or high baseline stress levels.

  14. Changing stress levels through gaining information on stress

    Directory of Open Access Journals (Sweden)

    S.N. Madu

    2002-09-01

    Full Text Available Objective: The aim of this research was to find out the effect of the Information Phase of a Stress Management Program (SMP on the perceptions of participants about their stress levels. Method: A total sample of 100 workers (nursing staff, private business men and women, laboratory assistants, the protective services [foreman and security staff], as well as people in human resources departments took part in this study. All the participants were from the Northern and Gauteng Provinces in South Africa. The Combined Hassles and Uplifts Scale (Folkman & Lazarus, 1989 was used as an instrument to measure the perceived stress level of participants in a SMP. Result: A significant reduction in stress levels was achieved among those who received the Information Phase of the SMP only, as well as those who received the whole stress management techniques. There was no significant difference between the amount of reduction in perceived stress-levels achieved among those that received the Information Phase of the SMP only, compared to that of those who received the whole techniques. Conclusion: The authors conclude that where the resources are limited, only the information phase of a SMP may be given to desiring clients. That should help to save time and money spent on participating in SMPs. This should however not discourage the use of the whole SPM, where affordable. Keywords: Stress Management Programs, Information Phase, Perception, Stress Level.

  15. Adapting Total Quality Management (TQM) to Government.

    Science.gov (United States)

    Swiss, James E.

    1992-01-01

    Total quality management will not work well in government agencies because of stress on products, not services; on well-defined consumer groups; on inputs/processes, not results; and on preoccupation with quality. An effective revised version emphasizes client feedback, performance monitoring, continuous improvement, and worker participation. (SK)

  16. Cumulative stress and autonomic dysregulation in a community sample.

    Science.gov (United States)

    Lampert, Rachel; Tuit, Keri; Hong, Kwang-Ik; Donovan, Theresa; Lee, Forrester; Sinha, Rajita

    2016-05-01

    Whether cumulative stress, including both chronic stress and adverse life events, is associated with decreased heart rate variability (HRV), a non-invasive measure of autonomic status which predicts poor cardiovascular outcomes, is unknown. Healthy community dwelling volunteers (N = 157, mean age 29 years) participated in the Cumulative Stress/Adversity Interview (CAI), a 140-item event interview measuring cumulative adversity including major life events, life trauma, recent life events and chronic stressors, and underwent 24-h ambulatory ECG monitoring. HRV was analyzed in the frequency domain and standard deviation of NN intervals (SDNN) calculated. Initial simple regression analyses revealed that total cumulative stress score, chronic stressors and cumulative adverse life events (CALE) were all inversely associated with ultra low-frequency (ULF), very low-frequency (VLF) and low-frequency (LF) power and SDNN (all p accounting for additional appreciable variance. For VLF and LF, both total cumulative stress and chronic stress significantly contributed to the variance alone but were not longer significant after adjusting for race and health behaviors. In summary, total cumulative stress, and its components of adverse life events and chronic stress were associated with decreased cardiac autonomic function as measured by HRV. Findings suggest one potential mechanism by which stress may exert adverse effects on mortality in healthy individuals. Primary preventive strategies including stress management may prove beneficial.

  17. Stress and sleep disturbances in female college students.

    Science.gov (United States)

    Lee, Shih-Yu; Wuertz, Caroline; Rogers, Rebecca; Chen, Yu-Ping

    2013-11-01

    To describe the sleep characteristics and examine the associations among perceived stress, sleep disturbances, depressive symptoms, and physical symptoms among female college students. A total of 103 students completed a battery of questionnaires. The students experienced high stress during the school year. The majority of them slept less than 6 hours during weekdays and experienced moderate fatigue. High stress levels are associated with sleep disturbances, less nocturnal total sleep time, higher fatigue severity, and more depressive symptoms. Perceived stress and sleep disturbances are significant predictors for depressive symptoms and physical symptoms. Compared to the good sleepers, the poor sleepers reported more daytime sleepiness, depressive symptoms, and physical symptoms. Interventions to reduce stress and improve sleep are critically needed in college education.

  18. Mechanical behavior of New Mexico rock salt in triaxial compression up to 2000C

    International Nuclear Information System (INIS)

    Wawersik, W.R.; Hannum, D.W.

    1979-07-01

    Three groups of tests are discussed to identify the relative and site-specific importance of deviator stress, confining pressure (mean stress), temperature, time (loading rate), and stress path. The three groups of experiments consist of (1) hydrostatic loading, (2) conventional triaxial compression tests (sigma 1 > sigma 2 = sigma 3 = const.), and (3) variable stress path tests including experiments at approximately constant sigma 1 and at constant mean stress. All data were generated on 100 mm-diameter specimens. The rock salt exhibited nonlinear response under all loading conditions, practically zero initial elastic limit and an apparent inseparability of permanent deformations into time-independent and time-dependent components. Pressure and temperature did not alter the elastic constants but affected the principal strain ratio, the ratio of volumetric to shear strain, rock salt ductility, and the ultimate stress. In particular, low pressure and temperature permitted pronounced dilatancy and loss in load bearing ability. Under such conditions the volumetric strains reached sizable fractions of the shear strains. Pressure remained important even at high temperature because it influenced the rate of shearing. Load path and stress history may be significant under deviatoric loading conditions and for large variations in pressure. 17 figures

  19. The Young and the Stressed

    DEFF Research Database (Denmark)

    Leppink, Eric W.; Odlaug, Brian L.; Lust, Katherine

    2016-01-01

    among college students, are limited. This study examined potential associations between perceived stress, academic achievement, physical/mental health, and impulse control disorders in young adults. A total of 1805 students completed an online survey and were included in the analysis. Responders were...... stress and numerous aspects of mental/physical health in young adults, which could be an important consideration for individuals working with college students.......High levels of stress are common among young adults, particularly those enrolled in college. These degrees of stress have shown numerous deleterious effects across both academic and health variables. Findings regarding the role of stress in the presentation of impulse control disorders, particular...

  20. Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohepatitis

    Directory of Open Access Journals (Sweden)

    Sarifakiogullari Serpil

    2005-11-01

    Full Text Available Abstract Background Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of nonalcoholic steatohepatitis. We aimed to investigate the total antioxidant response using a novel automated method in nonalcoholic steatohepatitis subjects. As a reciprocal measure, we also aimed to determine total peroxide level in the same plasma samples. Methods Twenty-two subjects with biopsy proven nonalcoholic steatohepatitis and 22 healthy controls were enrolled. Total antioxidant response and total peroxide level measurements were done in all participants. The ratio percentage of total peroxide level to total antioxidant response was regarded as oxidative stress index. Results Total antioxidant response of subjects with nonalcoholic steatohepatitis was significantly lower than controls (p In subjects with nonalcoholic steatohepatitis, fibrosis score was significantly correlated with total peroxide level, total antioxidant response and oxidative stress index (p 0.05. Conclusion Nonalcoholic steatohepatitis is associated with increased oxidant capacity, especially in the presence of liver fibrosis. The novel automated assay is a reliable and easily applicable method for total plasma antioxidant response measurement in nonalcoholic steatohepatitis.

  1. Total antioxidant and oxidant status in obese children without insulin resistance

    OpenAIRE

    Ayşegül Doğan Demir; Ufuk Erenberk; İlker Tolga Özgen; Emin Özkaya; Aysel Vahapoğlu Türkmen; M. Ruşen Dündaröz; Özcan Erel

    2014-01-01

    Objective: Oxidative stress in obese children may lead in adulthood serious conditions such as coronary heart diseases or type 2 diabetes mellitus. In childhood oxidative stress is associated with insulin resistance or extreme obesity. In this study, we aimed to evaluate oxidative stress status in moderately obese children without insulin resistance. Methods: A total of 38 obese children (21 male, 17 female) without insulin resistance, mean aged 9.4±3.8 years) and 51 normal weight children...

  2. Response of Different Genotypes of Faba Bean Plant to Drought Stress

    Directory of Open Access Journals (Sweden)

    Manzer H. Siddiqui

    2015-05-01

    Full Text Available Drought stress is one of the major abiotic stresses that are a threat to crop production worldwide. Drought stress impairs the plants growth and yield. Therefore, the aim of the present experiment was to select the tolerant genotype/s on the basis of moprpho-physiological and biochemical characteristics of 10 Vicia faba genotypes (Zafar 1, Zafar 2, Shebam, Makamora, Espan, Giza Blanka, Giza 3, C4, C5 and G853 under drought stress. We studied the effect of different levels of drought stress i.e., (i normal irrigation (ii mild stress (iii moderate stress, and (iv severe stress on plant height (PH plant−1, fresh weight (FW and dry weight (DW plant−1, area leaf−1, leaf relative water content (RWC, proline (Pro content, total chlorophyll (Total Chl content, electrolyte leakage (EL, malondialdehyde (MDA, hydrogen peroxide (H2O2 content, and activities of catalase (CAT, peroxidase (POD and superoxide dismutase (SOD of genotypes of faba bean. Drought stress reduced all growth parameters and Total Chl content of all genotypes. However, the deteriorating effect of drought stress on the growth performance of genotypes “C5” and “Zafar 1” were relatively low due to its better antioxidant enzymes activities (CAT, POD and SOD, and accumulation of Pro and Total Chl, and leaf RWC. In the study, genotype “C5” and “Zafar 1” were found to be relatively tolerant to drought stress and genotypes “G853” and “C4” were sensitive to drought stress.

  3. Effect of osmotic stress and post-stress recovery on the content of phenolics and properties of antioxidants in germinating seeds of grapevine Vitis californica

    Directory of Open Access Journals (Sweden)

    Stanisław Weidner

    2011-05-01

    Full Text Available The tested material consisted of grapevine Vitis californica stratified seeds germinated under optimum conditions (+25°C in water, under osmotic stress (-0.2 MPa in PEG solution and submitted to recovery after stress (+25°C in water. The germinating seeds were determined to contain tannins, catechins and the following phenolic acids: gallic, caffeic, p-coumaric and ferulic. The acids occurred in free, ester- and glycoside-bound forms. The dominant form of phenolic acids was the ester-bound fraction. Gallic acid was the most abundant phenolic acid in germinating seeds, while ferulic acid appeared in the smallest amounts. Our analysis of tannins demonstrated that osmotic stress depressed their concentration. Presence of catechin group compounds such as catechin and epicatechin was also determined. In each sample epicatechin was dominant. The total concentration of catechin increased under stress conditions and declined during post-stress recovery. Catechins are a constituent of tannins and their increase under osmotic stress is most probably caused by the breakdown of some tannins in seeds germinating under stress conditions. Samples submitted to osmotic stress were also found to contain less of total phenolic compounds, whereas in samples which underwent post-stress recovery the total level of phenolic compounds increased. Compared to extracts from seeds germinating under optimum conditions, osmotic stress depressed the capacity of extract to scavenge DPPH● (2,2-diphenyl-1-picrylhydrazyl and ABTS●+ – 2,2-Azino-bis (3-etylbenzothiazoline-6-sulfonic acid free radicals, but the antioxidant activity rose in seeds submitted to recovery after stress. Positive correlation was therefore demonstrated between the total content of phenolic acids in germinating grapevine seeds and the reducing power of extracts obtained from these seeds and their free radical scavenging activity. The results suggest that osmotic stress inhibits the activity of

  4. The Young and the Stressed: Stress, Impulse Control, and Health in College Students.

    Science.gov (United States)

    Leppink, Eric W; Odlaug, Brian L; Lust, Katherine; Christenson, Gary; Grant, Jon E

    2016-12-01

    High levels of stress are common among young adults, particularly those enrolled in college. These degrees of stress have shown numerous deleterious effects across both academic and health variables. Findings regarding the role of stress in the presentation of impulse control disorders, particular among college students, are limited. This study examined potential associations between perceived stress, academic achievement, physical/mental health, and impulse control disorders in young adults. A total of 1805 students completed an online survey and were included in the analysis. Responders were grouped by their overall score on the Perceived Stress Scale into mild, moderate, or severe. Severe perceived stress was associated with worse academic achievement and worse physical health, as well as higher rates of psychiatric and impulsive disorders. These findings may suggest associations between stress and numerous aspects of mental/physical health in young adults, which could be an important consideration for individuals working with college students.

  5. Multiaxial creep of tubes from Incoloy 800 H and Inconel 617 under static and cyclic loading conditions

    International Nuclear Information System (INIS)

    Penkalla, H.J.; Nickel, H.; Schubert, F.

    1989-01-01

    At temperatures above 800 0 C the material behaviour under mechanical load is determined by creep. The service of heat exchanging components leads to multiaxial loading conditions. For design and inelastic analysis of the component behaviour time dependent design values and suitable constitutive equations are necessary. The present report gives a survey of the approaches to describing creep under multiaxial loading. Norton's law and v. Mises' theory are applied. The load combinations of internal pressure, tensile and torsional stress are studied more closely, cyclic stress superposition in the tensile-pulsating range is discussed and cases of partial relaxation are examined. Experimental results are presented for the loading conditions discussed, and satisfactory agreement between theory and experiment has been found up to now for these results. Regarding lifetime determination under multiaxial creep load, a more precise analysis of creep damage is presented suggesting a suitable deviatoric stress for evaluation in the long-time range. (orig.)

  6. Gas migration in argillaceous rock

    International Nuclear Information System (INIS)

    Alonso, E. E.; Olivella, S.

    2007-01-01

    The intrinsic gas permeability of fractured argillaceous rocks depends on the current structure of micro-cracks and fissures of the rock. They are a consequence of the initial state and the subsequent deformations induced by stress and gas pressure changes. Stresses are also coupled with fluid pressures and, therefore, gas flow and mechanical behaviour are intensely coupled. Laboratory experiments, aimed at determining intrinsic permeability, show the relevant effect of volumetric deformations induced by isotropic, as well as deviatoric stress changes. The relevance, in practice, of the flow-mechanical coupling is illustrated by means of some results obtained during the performance of the drift scale test (DST) in fractured tuff in the Yucca Mountain facility. The technique of embedding discontinuities in continuum thermo-hydro-mechanical elements is capable of reproducing observed features of gas flow migration in clayey rocks. An example is described. It is believed that the developed approach provides a powerful computational procedure to handle complex gas phenomena in clayey rocks. (author)

  7. Stress and Posttraumatic Stress in Mothers of Children With Type 1 Diabetes.

    Science.gov (United States)

    Rechenberg, Kaitlyn; Grey, Margaret; Sadler, Lois

    2017-05-01

    The onset of acute and chronic illness in children frequently triggers episodes of stress and posttraumatic stress symptoms (PTSS) in mothers. Mothers of children with type 1 diabetes (T1D) consistently report high levels of stress and PTSS. The purpose of this integrative review was to review and synthesize the published empirical research. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used to conduct this integrative literature review. A total of 19 studies were identified from a sample of 128. Stress and PTSS were prevalent in mothers of youth with T1D. While PTSS was most severe at disease onset, symptoms often persisted 1 to 5 years after diagnosis. The diagnosis of T1D in a child was traumatic for mothers. Stress and PTSS in mothers adversely affected children's health. Management of stress symptoms in mothers may lead to improved behavioral and metabolic outcomes in children.

  8. [Association between occupational psychological stress and metabolic syndrome].

    Science.gov (United States)

    Liu, Herong; Song, Hui; Tian, Rulong; Chen, Lijun; Zhang, Wei; Qiang, Yan

    2015-02-01

    To investigate the association between occupational psychological stress and metabolic syndrome (MS) in Hui and Han populations in Ningxia, China. A 1:1 matched case-control study was performed. A total of 600 unrelated patients aged from 20 to 60 years who were clearly diagnosed with MS in General Hospital of Ningxia Medical University and Wuzhong People's Hospital from October 2011 to October 2012 were collected as the case group (MS group). A total of 600 healthy people who underwent a regular health examination in the same hospital during the same period were selected as the control group with matched gender, nationality, and age (≤ ± 3 years). The self-designed questionnaire was used to investigate the general situations and do the physical examination, and the fasting venous blood samples were collected for laboratory biochemical blood tests. The Occupational Stress Inventory (OSI) was used to investigate the subjects' occupational stress factors and stress levels. With the increase in stress levels, the levels of WC, FPG, TG, AST, and UA were increased, WHR, SBP, and DBP first increased and then decreased, and the level of HDL-C increased. There were statistically significant differences in these parameters between the two groups (P occupational psychological stress test results showed that the total score of stress factors (t = 6.676, P 0.05). There were no significant differences in the total score of stress factors and the score of each factor between Hui and Han groups (P>0.05). The relative risks of MS in the people with moderate stress exposure were 2.325 and 2.331 times those in the people with mild stress exposure before and after adjustment for age, gender, education level, marriage status, smoking, and drinking, and the relative risks for MS in the people with severe stress exposure were 3.000 and 3.126 times those in the people with mild stress exposure. There were significant differences in the detection rates of abdominal obesity, high TG

  9. The Influence of Oral Carbohydrate Solution Intake on Stress Response before Total Hip Replacement Surgery during Epidural and General Anaesthesia.

    Science.gov (United States)

    Çeliksular, M Cem; Saraçoğlu, Ayten; Yentür, Ercüment

    2016-06-01

    The effects of oral carbohydrate solutions, ingested 2 h prior to operation, on stress response were studied in patients undergoing general or epidural anaesthesia. The study was performed on 80 ASA I-II adult patients undergoing elective total hip replacement, which were randomized to four groups (n=20). Group G patients undergoing general anaesthesia fasted for 8 h preoperatively; Group GN patients undergoing general anaesthesia drank oral carbohydrate solutions preoperatively; Group E patients undergoing epidural anaesthesia fasted for 8 h and Group EN patients undergoing epidural anaesthesia drank oral carbohydrate solutions preoperatively. Groups GN and EN drank 800 mL of 12.5% oral carbohydrate solution at 24:00 preoperatively and 400 mL 2 h before the operation. Blood samples were taken for measurements of glucose, insulin, cortisol and IL-6 levels. The effect of preoperative oral carbohydrate ingestion on blood glucose levels was not significant. Insulin levels 24 h prior to surgery were similar; however, insulin levels measured just before surgery were 2-3 times higher in groups GN and EN than in groups G and E. Insulin levels at the 24(th) postoperative hour in epidural groups were increased compared to those at basal levels, although general anaesthesia groups showed a decrease. From these measurements, only the change in Group EN was statistically significant (poral carbohydrate nutrition did not reveal a significant effect on surgical stress response.

  10. Thermally induced motion of marine sediments resulting from disposal of radioactive wastes

    International Nuclear Information System (INIS)

    Chavez, P.F.; Dawson, P.R.

    1981-01-01

    Coupled creep and heat transfer calculations have been performed to assess the sensitivity of heat load, viscosity, and canister density on the motion of waste canisters buried in marine sediments. Results indicate that no upward movement is predicted for heat loads remaining within the metallurgical and geochemical constraints placed on the temperature of sediments near the canister for the times analyzed. Upward movement of the canister is again not observed in calculations involving reasonable variations of the sediment viscosity and canister density. Maximum effective deviatoric stress levels due to thermally induced differential body forces are significantly less than the sediment's short term peak strength

  11. Mindfulness-based stress reduction as a stress management intervention for healthy individuals: a systematic review.

    Science.gov (United States)

    Sharma, Manoj; Rush, Sarah E

    2014-10-01

    Stress is a global public health problem with several negative health consequences, including anxiety, depression, cardiovascular disease, and suicide. Mindfulness-based stress reduction offers an effective way of reducing stress by combining mindfulness meditation and yoga in an 8-week training program. The purpose of this study was to look at studies from January 2009 to January 2014 and examine whether mindfulness-based stress reduction is a potentially viable method for managing stress. A systematic search from Medline, CINAHL, and Alt HealthWatch databases was conducted for all types of quantitative articles involving mindfulness-based stress reduction. A total of 17 articles met the inclusion criteria. Of the 17 studies, 16 demonstrated positive changes in psychological or physiological outcomes related to anxiety and/or stress. Despite the limitations of not all studies using randomized controlled design, having smaller sample sizes, and having different outcomes, mindfulness-based stress reduction appears to be a promising modality for stress management. © The Author(s) 2014.

  12. Stress no trabalho do enfermeiro Estrés en el trabajo del enfermero Stress the nurse's work

    Directory of Open Access Journals (Sweden)

    José Roberto Alves da Costa

    2003-09-01

    Full Text Available Este estudo avaliou o stress associado ao trabalho do enfermeiro no trabalho com o portador de transtorno mental inserido no contexto do hospital psiquiátrico. Trata-se de pesquisa quantitativa, analítica, realizada em sete hospitais psiquiátricos da cidade de Fortaleza, Ceará. Utilizou-se os seguintes instrumentos: dados sociodemográficos para descrição da amostra e um inventário para identificar os sintomas de stress no enfermeiro. A população total abrangeu 48 participantes e a amostra 42, a maioria do sexo feminino, o que corresponde a 92,9% do total. Os resultados mostram que em 62% da amostra não apresentaram stress, 30,9% encontravam-se na fase de Resistência e apenas 7,1% na fase de Exaustão. Não houve associação estatisticamente significativa entre a variável tempo de trabalho com o portador de transtorno mental e sintomas de stress. Portanto, o presente estudo não evidenciou a ocorrência do stress nesses profissionais enfermeiros.Este estudio evaluó el estrés del enfermero asociado al trabajo con el portador de trastorno mental en el contexto del hospital psiquiátrico. Se trata de una investigación cuantitativa, analítica, realizada en siete hospitales psiquiátricos, en la ciudad de Fortaleza, Ceará. Se utilizó los siguientes instrumentos: datos sociodemográficos para la descripción de la muestra y un inventario para identificar los síntomas de stress en el enfermero. La población total abarcó 48, siendo la muestra de 42 participantes, la mayoría del sexo femenino, lo que corresponde al 92,9% del total. Los resultados mostraron que no hubo stress en el 62% de los participantes, el 30,9% se encontró en fase de resistencia y el 7,1% en fase de exhausto. No hubo asociación estadísticamente significativa entre el tiempo de trabajo y los síntomas de stress. Por lo tanto, el presente estudio no evidenció la ocurrencia de stress en los profesionales enfermeros.The aim of this study was to appraise stress

  13. Oxidative Stress in BPH.

    Science.gov (United States)

    Savas, M; Verit, A; Ciftci, H; Yeni, E; Aktan, E; Topal, U; Erel, O

    2009-01-01

    In the present study, we investigated the relationship between potency of oxidative stress and BPH and this may assist to contribute to the realistic explanation of the ethiopathogenesis of BPH. Seventy four newly diagnosed men with BPH (mean age: 54+/-11.2), who had not undergone any previous treatment for BPH, and 62 healthy volunteers (mean age: 55+/-14) were enrolled in the present study. To determine the antioxidative status of plasma, total antioxidant capacity (TAC) was calculated, and to determine the oxidative status of plasma (TOS) total peroxide levels were measured. The ratio of TAC to total peroxide was accepted as an indicator of oxidative stress (OSI). Data are presented as mean SD +/- unless specified. Student t-test and correlation analyses were used to evaluate the statistical significance differences in the median values recorded for all parameters between BPH and control group. Plasma TAC TOS were found in patients and controls (1.70 +/- 0.32, 1.68 +/- 0.19 micromol Trolox Equiv./L), (12.48 +/- 1.98, 12.40 +/- 1.14 micromol / L) respectively. OSI was calculated as 7.57 +/- 1.91, 7.48 +/- 1.33, respectively. Plasma TAC, TOS and OSI levels were not found to be significantly difference between patients and control subjects (p>0.05, p>0.05, p>0.05). The present study has shown that there were not relationship between potency of oxidative stress and BPH. Further well designed studies should be planned to find out whether the oxidative stress-related parameters play role in BPH as an interesting pathology in regard of the etiopathogenesis.

  14. Finite element implementation of a thermo-damage-viscoelastic constitutive model for hydroxyl-terminated polybutadiene composite propellant

    Science.gov (United States)

    Xu, Jinsheng; Han, Long; Zheng, Jian; Chen, Xiong; Zhou, Changsheng

    2017-11-01

    A thermo-damage-viscoelastic model for hydroxyl-terminated polybutadiene (HTPB) composite propellant with consideration for the effect of temperature was implemented in ABAQUS. The damage evolution law of the model has the same form as the crack growth equation for viscoelastic materials, and only a single damage variable S is considered. The HTPB propellant was considered as an isotropic material, and the deviatoric and volumetric strain-stress relations are decoupled and described by the bulk and shear relaxation moduli, respectively. The stress update equations were expressed by the principal stresses σ_{ii}R and the rotation tensor M, the Jacobian matrix in the global coordinate system J_{ijkl} was obtained according to the fourth-order tensor transformation rules. Two models having complex stress states were used to verify the accuracy of the constitutive model. The test results showed good agreement with the strain responses of characteristic points measured by a contactless optical deformation test system, which illustrates that the thermo-damage-viscoelastic model perform well at describing the mechanical properties of an HTPB propellant.

  15. Microplane modelling of shape memory alloys

    International Nuclear Information System (INIS)

    Kadkhodaei, M; Salimi, M; Rajapakse, R K N D; Mahzoon, M

    2007-01-01

    A three-dimensional (3D) constitutive model based on a statically constrained microplane theory with volumetric-deviatoric split is proposed for polycrystalline shape memory alloys (SMAs) under multiaxial loading paths. Microplane governing equations are 1D stress-strain relations for normal and shear stresses on each microplane, in which suitable relationships between the microscopic and macroscopic quantities are considered so that switching between elastic and inelastic local responses automatically occurs according to the macroscopic response of SMA without additional constraint. Shear stress on each microplane is expressed by the resultant shear component within the plane to overcome directional bias and to prevent the appearance of shear strain in a pure axial loading or axial strain in a pure shear loading while microplane formulations based on two shear directions may predict such impractical results. The behaviour of SMA under simple and complicated loadings has been studied. In nonproportional loading paths, the model shows interaction between stress components, as well as deviation from normality. Predicted results from the model are in good agreement with those of the existing theoretical and experimental investigations

  16. Differential Effects of Psychological and Physical Stress on the Sleep Pattern in Rats

    OpenAIRE

    Cui, Ranji; Li, Bingjin; Suemaru, Katsuya; Araki, Hiroaki

    2007-01-01

    In the present study, we investigated the acute effects of 2 different kinds of stress, namely physical stress (foot shock) and psychological stress (non-foot shock) induced by the communication box method, on the sleep patterns of rats. The sleep patterns were recorded for 6 h immediately after 1 h of stress. Physical and psychological stress had almost opposite effects on the sleep patterns: In the physical stress group, hourly total rapid eye movement (REM) sleep and total non-REM sleep we...

  17. Mechanical behaviour and rupture in clayey rocks studied by x-ray micro tomography; Comportement mecanique et rupture dans les roches argileuses etudies par micro tomographie a rayons X

    Energy Technology Data Exchange (ETDEWEB)

    Lenoir, N

    2006-03-15

    Within the framework of feasibility studies of underground repositories for radioactive waste, the study of permeability evolution with damage of the host layer is crucial. The goals of this work were: (i) to characterize experimentally the damage of two clayey rocks (BEAUCAIRE MARL and EAST SHALE) with x-ray micro tomography, (ii) to develop a high pressure triaxial set-up adapted to permeability measurement on very low permeability rocks.A number of original triaxial devices have been realised to characterize damage of clayey rocks, under deviatoric loading, with x-ray micro tomography on a synchrotron beamline at the ESRF (Grenoble). Localized damage and its evolution have been characterized at a fine scale (of order of ten microns). Digital image correlation techniques, extended to 3d images, have been used to measure incremental strain fields from tomographic images. we demonstrated that these techniques are very useful in the study of the localized damage of geo-materials and especially for the initiation. A high pressure triaxial device has been realised to measure permeability evolution of the east shale as a function of applied stress (isotropic and deviatoric). The particularity of this set-up is the small size of the test specimen (cylinder of 10 mm in diameter and 20 mm in height) which allows significant reduction of test duration. (author)

  18. Mechanical behaviour and rupture in clayey rocks studied by x-ray micro tomography

    International Nuclear Information System (INIS)

    Lenoir, N.

    2006-03-01

    Within the framework of feasibility studies of underground repositories for radioactive waste, the study of permeability evolution with damage of the host layer is crucial. The goals of this work were: (i) to characterize experimentally the damage of two clayey rocks (BEAUCAIRE MARL and EAST SHALE) with x-ray micro tomography, (ii) to develop a high pressure triaxial set-up adapted to permeability measurement on very low permeability rocks.A number of original triaxial devices have been realised to characterize damage of clayey rocks, under deviatoric loading, with x-ray micro tomography on a synchrotron beamline at the ESRF (Grenoble). Localized damage and its evolution have been characterized at a fine scale (of order of ten microns). Digital image correlation techniques, extended to 3d images, have been used to measure incremental strain fields from tomographic images. we demonstrated that these techniques are very useful in the study of the localized damage of geo-materials and especially for the initiation. A high pressure triaxial device has been realised to measure permeability evolution of the east shale as a function of applied stress (isotropic and deviatoric). The particularity of this set-up is the small size of the test specimen (cylinder of 10 mm in diameter and 20 mm in height) which allows significant reduction of test duration. (author)

  19. Application of laser interferometry for assessment of surface residual stress by determination of stress-free state

    International Nuclear Information System (INIS)

    Kim, Dong Won; Kwon, Dong Il; Lee, Nak Kyu; Choi, Tae Hoon; Na, Kyoung Hoan

    2003-01-01

    The total relaxed stress in annealing and the thermal strain/stress were obtained from the identification of the residual stress-free state using Electronic Speckle Pattern Interferometry (ESPI). The residual stress fields in case of both single and film/substrate systems were modeled using the thermo-elastic theory and the relationship between relaxed stresses and displacements. We mapped the surface residual stress fields on the indented bulk Cu and the 0.5 μm Au film by ESPI. In indented Cu, the normal and shear residual stress are distributed over -1.7 GPa to 700 MPa and -800 GPa to 600 MPa respectively around the indented point and in deposited Au film on Si wafer, the tensile residual stress is uniformly distributed on the Au film from 500 MPa to 800 MPa. Also we measured the residual stress by the X-Ray Diffractometer (XRD) for the verification of above residual stress results by ESPI

  20. Effect of Stress-Response Psycho-Training on the Stress Levels of Mothers with Autistic Children

    Science.gov (United States)

    Karaman, Ömer

    2018-01-01

    The aim of the study was to assess the effect of stress-response psycho-training on the stress levels of mothers with autistic children. The research was experimental in design encompassing a pretest-posttest model with control and placebo groups. Participation in the study was voluntary with a total of 28 mothers of autistic children included…

  1. Total antioxidant and oxidant status in obese children without insulin resistance

    Directory of Open Access Journals (Sweden)

    Ayşegül Doğan Demir

    2014-06-01

    Full Text Available Objective: Oxidative stress in obese children may lead in adulthood serious conditions such as coronary heart diseases or type 2 diabetes mellitus. In childhood oxidative stress is associated with insulin resistance or extreme obesity. In this study, we aimed to evaluate oxidative stress status in moderately obese children without insulin resistance. Methods: A total of 38 obese children (21 male, 17 female without insulin resistance, mean aged 9.4±3.8 years and 51 normal weight children (25 male, 26 female as the control group, mean aged 9.3±3.9 years were enrolled to the study. Total oxidative status (TOS, total antioxidant capacity (TAC were measured and oxidative stress index (OSI was calculated. Results: The results reveal that obese children had lower TAC than normal weight children (2,27±0,28 vs. 2.76±0.35 mmol Trolox Eq./L; p<0,001. There was no statistical difference between obese and control groups regarding TOS (6,08±3,63 vs 5.25±4.16 μmol H2O2 Eq./L; p=0.333. OSI was higher in obese group (2.65±1.52 vs 1.92±1.56; p=0.029 Conclusion: Balance between oxidant and antioxidant system is disrupted due to the reduced TAC even in moderately obese children without insulin resistance. Further studies should also be performed to evaluate the beneficial effects of dietary intake of antioxidants in these children.

  2. Permeability of WIPP Salt During Damage Evolution and Healing

    International Nuclear Information System (INIS)

    BODNER, SOL R.; CHAN, KWAI S.; MUNSON, DARRELL E.

    1999-01-01

    The presence of damage in the form of microcracks can increase the permeability of salt. In this paper, an analytical formulation of the permeability of damaged rock salt is presented for both initially intact and porous conditions. The analysis shows that permeability is related to the connected (i.e., gas accessible) volumetric strain and porosity according to two different power-laws, which may be summed to give the overall behavior of a porous salt with damage. This relationship was incorporated into a constitutive model, known as the Multimechanism Deformation Coupled Fracture (MDCF) model, which has been formulated to describe the inelastic flow behavior of rock salt due to coupled creep, damage, and healing. The extended model was used to calculate the permeability of rock salt from the Waste Isolation Pilot Plant (WIPP) site under conditions where damage evolved with stress over a time period. Permeability changes resulting from both damage development under deviatoric stresses and damage healing under hydrostatic pressures were considered. The calculated results were compared against experimental data from the literature, which indicated that permeability in damaged intact WIPP salt depends on the magnitude of the gas accessible volumetric strain and not on the total volumetric strain. Consequently, the permeability of WIPP salt is significantly affected by the kinetics of crack closure, but shows little dependence on the kinetics of crack removal by sintering

  3. Investigation of drought stress in pepino (solanum muricatum ait. cv. miskl) leaves

    International Nuclear Information System (INIS)

    Duman, S.; Sivaci, A.

    2015-01-01

    In this study, the effects of drought stress on pepino seedlings (Solanum muricatum cv. Miski) under natural greenhouse conditions were examined. The control plants were watered at field capacity, and the stress group was not watered. Samples were collected on the 6th, 12th, 24th and 36th days from the leaves of S. muricatum seedlings that, were exposed to drought stress. The relative water content, the total phenolic compounds, and the malondialdehyde, total photosynthetic pigments (chlorophyll a, chlorophyll b and carotenoids), and proline contents in these samples were determined. Depending on drought stress, the relative water content, the chlorophyll a, chlorophyll b and carotenoid contents, and the total chlorophylls were found to be lower in the stress group compared with the control group. In contrast, the total phenolic compounds (24th and 36th days) and the proline (12th, 24th and 36th days) levels increased significantly compared with the control group. In addition, a significant increase in the malondialdehyde contents was obtained on the 36th day in the stress group compared with the control group. Such studies may be important for evaluation of metabolic changes in pepino under the drought stress. (author)

  4. Oxidative stress in hepatitis C infected end-stage renal disease subjects

    Directory of Open Access Journals (Sweden)

    Koylu Ahmet O

    2006-07-01

    Full Text Available Abstract Background Both uremia and hepatitis C infection is associated with increased oxidative stress. In the present study, we aimed to find out whether hepatitis C infection has any impact on oxidative stress in hemodialysis subjects. Methods Sixteen hepatitis C (+ hemodialysis subjects, 24 hepatitis C negative hemodialysis subjects and 24 healthy subjects were included. Total antioxidant capacity, total peroxide level and oxidative stress index were determined in all subjects. Results Total antioxidant capacity was significantly higher in controls than hemodialysis subjects with or without hepatitis C infection (all p 0.05/3. Conclusion Oxidative stress is increased in both hepatitis C (+ and hepatitis C (- hemodialysis subjects. However, hepatitis C infection seems to not cause any additional increase in oxidative stress in hemodialysis subjects and it may be partly due to protective effect of dialysis treatment on hepatitis C infection.

  5. Dynamic changes in saliva after acute mental stress

    Science.gov (United States)

    Naumova, Ella A.; Sandulescu, Tudor; Bochnig, Clemens; Khatib, Philipp Al; Lee, Wing-Kee; Zimmer, Stefan; Arnold, Wolfgang H.

    2014-01-01

    Stress-related variations of fluoride concentration in supernatant saliva and salivary sediment, salivary cortisol, total protein and pH after acute mental stress were assessed. The hypothesis was that stress reactions have no influence on these parameters. Thirty-four male students were distributed into two groups: first received the stress exposure followed by the same protocol two weeks later but without stress exposure, second underwent the protocol without stress exposure followed by the stress exposure two weeks later. The stressor was a public speech followed by tooth brushing. Saliva was collected before, immediately after stress induction and immediately, at 10, 30 and 120 min. after tooth brushing. Cortisol concentrations, total protein, intraoral pH, and fluoride content in saliva were measured. The data were analyzed statistically. Salivary sediment was ca 4.33% by weight of whole unstimulated saliva. Fluoride bioavailability was higher in salivary sediment than in supernatant saliva. The weight and fluoride concentration was not altered during 2 hours after stress exposure. After a public speech, the salivary cortisol concentration significantly increased after 20 minutes compared to the baseline. The salivary protein concentration and pH also increased. Public speaking influences protein concentration and salivary pH but does not alter the fluoride concentration of saliva. PMID:24811301

  6. The effects of propolis extract on ovarian tissue and oxidative stress in rats with maternal separation stress

    Directory of Open Access Journals (Sweden)

    Atefeh Arabameri

    2017-09-01

    Full Text Available Abstract Background: Stress in infancy has dramatic effects on different systems, including the nervous system, endocrine, immune, reproductive and etc. Objective: The purpose of this study was to investigate the effects of extract of Iranian propolis (EIP on ovarian tissue and oxidative stress in rats with maternal separation stress. Materials and Methods: 48 immature female rats were divided randomly into six groups. 1 Control group, 2 Control group+saline, 3 Stress group, includes infants that were separated from their mothers 6 hr/day, the 4th, 5th and 6th groups consisted of infants who in addition to daily stress received 50, 100 and 200 mg/kg of EIP, respectively. Then serum corticosterone, 17-beta-estradiol, malondialdehyde, total superoxide dismutase, glutathione peroxidase and ferric reducing antioxidant power levels were measured. The ovarian sections were stained by H&E, PAS, and TUNEL methods and were studied with optical microscopy. Results: Stress increased the blood serum corticosterone levels and 17-beta-estradiol reduced significantly (p<0.001 and EIP prevented from this changes (p<0.01. EIP significantly increased the number of ovarian follicles, oocytes and oocytes diameter in neonatal rat following stress (p<0.01. EIP also significantly decreased the number of atretic follicles, TUNEL+granulosa cells, malondialdehyde levels and increased ferric reducing antioxidant power, total superoxide dismutase and glutathione peroxidase serum levels in neonatal rats following stress. The dose of 200 mg/kg EIP was more effective. Conclusion: This Study showed that the Iranian Propolis significantly could prevent oxidative stress and histopathological changes in the ovary of the neonatal rat the following stress.

  7. Instrumental and laboratory assessment of stressful remodelling processes in bone tissue at total hip replacement

    Directory of Open Access Journals (Sweden)

    E.V. Karjakina

    2010-06-01

    Full Text Available Research objective is to estimate stressful remodelling features of bone tissue according to the densitometry data and to the level of biochemical markers of bone resorption and formation in total hip replacement (THR. Bone tissue mineral density (BTMD, condition of calcium-phosphoric metabolism and biochemical markers of bone formation (osteocalcin and bone isoenzyme of alkaline phosphatase and resorption (С-terminal bodypeptide of the I type collagen have been determined in 52 patients with coxarthrosis of ll-lll stages with marked joint dysfunction before and after THR. The control group included 24 donors. The data were considered to be reliable when the probability index was р<0,05. The reliable (р<0,05 change of BTMD was determined only in 3-6 months after the operation, whereas the change of biochemical markers of remodeling had already been done after 1,5-3 months, allowing to define the group of patients with obvious negative bone balance: strong predominance of resorption processes without compensation of the subsequent adequate osteogenesis, that subsequently could lead to significant bone tissue deficiency in the area adjacent to the endoprosthesis. Changes of indices of calcium-phosphoric metabolism were not certain during the investigation term. ln conclusion it is to state that biochemical markers of remodeling in comparison with BTMD allow to estimate objectively features of adaptive bone tissue remodeling after THR in earlier periods and to define group of patients with sharp intensification of metabolism and obvious negative bone balance

  8. CHALLENGE-STRESS AND HINDRANCE-STRESS IN THE SOUTHEAST ASIAN HOTEL SECTOR

    Directory of Open Access Journals (Sweden)

    Kamaazura Abu Abu

    2015-05-01

    Full Text Available The hospitality industry is an entity that is continuously determined by varying new demands and the needs of its customers. This ever-changing and complex working environment has caused and become a source of stress for the hospitality industries’ workforce. Workplace stress is increasing from year to year and has become a focus of research interest in recent years. Responding to the demands of management who require a more precise understanding of the issues of workplace stress, researchers have conducted studies on a total of 115 respondents from a 3 star-hotel and a 4 star-hotel. The personnel involved came from the food and beverage departments, room services and the front offices, whose daily routines involved direct face to face serving activities and fulfilling their customers’ demands. Using the Statistical Package for Social Science (SPSS version 19.0 and AMOS version 18.0, the results of Exploratory Data Analysis (EFA and Confirmatory Data Analysis (CFA have confirmed that there are two stress factors, namely challenge stress and hindrance stress. Both of these stress factors have a significantly negative relation to one another. Understanding these dimensions in detail can help the hospitality organizations to be well prepared for the task of motivating their employees.

  9. Oxidative Stress and Antioxidant System in Periodontitis

    Science.gov (United States)

    Wang, Yue; Andrukhov, Oleh; Rausch-Fan, Xiaohui

    2017-01-01

    Periodontitis is a common inflammatory disease, which is initiated by bacterial infection and subsequently progressed by aberrant host response. It can result in the destruction of teeth supporting tissues and have an influence on systemic health. When periodontitis occurs, reactive oxygen species, which are overproduced mostly by hyperactive neutrophils, could not be balanced by antioxidant defense system and cause tissues damage. This is characterized by increased metabolites of lipid peroxidation, DNA damage and protein damage. Local and systemic activities of antioxidants can also be influenced by periodontitis. Total antioxidant capacity, total oxidant status and oxidative stress index have been used to evaluate the oxidative stress associated with periodontitis. Studies have confirmed that inflammatory response in periodontitis is associated with an increased local and systemic oxidative stress and compromised antioxidant capacity. Our review focuses on increased oxidative stress in periodontal disease, specifically, on the relationship between the local and systemic biomarkers of oxidative stress and periodontitis and their association with the pathogenesis of periodontitis. Also, the relationship between periodontitis and systemic inflammation, and the effects of periodontal therapy on oxidative stress parameters will be discussed. PMID:29180965

  10. The modified indeterminate couple stress model: Why Yang et al.'s arguments motivating a symmetric couple stress tensor contain a gap and why the couple stress tensor may be chosen symmetric nevertheless

    OpenAIRE

    Münch, Ingo; Neff, Patrizio; Madeo, Angela; Ghiba, Ionel-Dumitrel

    2015-01-01

    We show that the reasoning in favor of a symmetric couple stress tensor in Yang et al.'s introduction of the modified couple stress theory contains a gap, but we present a reasonable physical hypothesis, implying that the couple stress tensor is traceless and may be symmetric anyway. To this aim, the origin of couple stress is discussed on the basis of certain properties of the total stress itself. In contrast to classical continuum mechanics, the balance of linear momentum and the balance of...

  11. Elasto-plastic model for transversely isotropic Tournemire shale based on microstructure approach

    International Nuclear Information System (INIS)

    Abdi, H.; Evgin, E.; Fall, M.; Nguyen, T.S.; Labrie, D.; Barnichon, J.D.; Su, G.; Simon, R.

    2012-01-01

    Document available in extended abstract form only. Argillaceous formations being considered as potential host rocks for the geological disposal of nuclear wastes are usually characterized by the presence of bedding planes, resulting in anisotropy of their strength and deformation properties. A laboratory program of uniaxial tests, triaxial tests, cyclic tests, and Brazilian tests with concurrent monitoring of acoustic emission was performed in order to determine the above properties. The experimental results and their interpretation are presented in detail in a companion paper (Abdi et al., 2012, in these proceedings). Typical results from triaxial tests indicate the following behaviour: 1. There is a strong dependence of the stress-strain behaviour with the loading orientation with respect to the bedding planes. 2. There are four distinct zones of the stress strain curve: a crack and/or bedding closure zone; an elastic zone, a plastic zone with strain hardening, and a collapse zone after the peak that leads abruptly to a residual strength value. 3. There is damage, especially after the peak, resulting in the degradation of the stiffness as shown by unloading-reloading cycles. In order to reproduce the above behaviour, we adopted a classical elasto-plastic framework. In the elastic range, the transversely isotropic nature of the material is taken into account by the adoption of an elastic stiffness matrix that requires five independent elastic constants. These elastic constants show degradation with the accumulated damage. Using the deviatoric plastic strain as a measure of damage, we expressed functional relationships for these constants, using the results of cyclic triaxial tests. For the plastic behaviour, we used a Mohr-Coulomb yield criterion which takes into account the relative orientation of the applied stress and the bedding planes, and also strain hardening and softening. In this work we used the deviatoric plastic strain as the hardening parameter in

  12. User's guide to MITRE, a stress analysis program for Mitred pipe bends

    International Nuclear Information System (INIS)

    Beveridge, D.C.; Carmichael, G.D.T.

    1977-12-01

    The MITRE computer program calculates the flexibility factor, circumferential and longitudinal inside and outside surface bending stress ratio, pressure stresses, and total stresses around the mitre section at both the mid and edge section locations of a pressurised multimitred bend under in and/or out of plane bending. Additionally, the circumferential and longitudinal strains, equivalent stress (Mises and Tresca), principal stresses, and total stresses perpendicular and parallel to the edge section at the inside and outside surfaces are calculated for the edge section. The stresses sustained by single mitres subjected to internal pressure can also be evaluated for bends with either 'long' or 'short' leg lengths. Results are tabulated and plotted in graphical form on the line printer. (author)

  13. Oxidative stress in hepatitis C infected end-stage renal disease subjects

    OpenAIRE

    Koylu Ahmet O; Aslan Mehmet; Bolukbas Filiz F; Bolukbas Cengiz; Horoz Mehmet; Selek Sahbettin; Erel Ozcan

    2006-01-01

    Abstract Background Both uremia and hepatitis C infection is associated with increased oxidative stress. In the present study, we aimed to find out whether hepatitis C infection has any impact on oxidative stress in hemodialysis subjects. Methods Sixteen hepatitis C (+) hemodialysis subjects, 24 hepatitis C negative hemodialysis subjects and 24 healthy subjects were included. Total antioxidant capacity, total peroxide level and oxidative stress index were determined in all subjects. Results T...

  14. Updated of the events tree of total loss of power at the site, SBO, taking into account the results of stress tests and methodological updates, convolution, and hydraulic power recovery from model RCPs

    International Nuclear Information System (INIS)

    Lopez Lorenzo, M. A.; Perez Martin, F.

    2013-01-01

    In this paper, is described a tree of events to an accident loss total power at the site (SBO) considering, first the results of stress tests arising from the Fukushima accident and moreover, various methodological updates related to this initiating event.

  15. Plasma Total Cysteine and Cardiovascular Risk Burden: Action and Interaction

    OpenAIRE

    De Chiara, Benedetta; Sedda, Valentina; Parolini, Marina; Campolo, Jonica; De Maria, Renata; Caruso, Raffaele; Pizzi, Gianluigi; Disoteo, Olga; Dellanoce, Cinzia; Corno, Anna Rosa; Cighetti, Giuliana; Parodi, Oberdan

    2012-01-01

    We hypothesized that redox analysis could provide sensitive markers of the oxidative pathway associated to the presence of an increasing number of cardiovascular risk factors (RFs), independently of type. We classified 304 subjects without cardiovascular disease into 4 groups according to the total number of RFs (smoking, hypertension, hypercholesterolaemia, hyperhomocysteinaemia, diabetes, obesity, and their combination). Oxidative stress was evaluated by measuring plasma total and reduced h...

  16. Failure criterion of concrete type material and punching failure analysis of thick mortar plate

    International Nuclear Information System (INIS)

    Ohno, T.; Kuroiwa, M.; Irobe, M.

    1979-01-01

    In this paper falure surface of concrete type material is proposed and its validity to structural analysis is examined. The study is an introductory part of evaluation for ultimate strength of reinforced and prestressed concrete structures in reactor technology. The failure surface is expressed in a linear form in terms of octahedral normal and shear stresses. Coefficient of the latter stress is given by a trigonometric series in threefold angle of similarity. Hence, its meridians are multilinear and traces of its deviatoric sections are smooth curves having periodicity of 2π/3 around space diagonal in principal stress space. The mathematical expression of the surface has an arbitraty number of parameters so that material test results are well reflected. To confirm the effectiveness of proposed failure criterion, experiment and numerical analysis by the finite element method on punching failure of thick mortar plate in axial symmetry are compared. In the numerical procedure yield surface of the material is assumed to exist mainly in compression region, since a brittle cleavage or elastic fracture occurs in the concrete type material under stress state with tension, while a ductile or plastic fracture occurs under compressive stress state. (orig.)

  17. Enhanced oxidative stress in the jasmonic acid-deficient tomato mutant def-1 exposed to NaCl stress.

    Science.gov (United States)

    Abouelsaad, Ibrahim; Renault, Sylvie

    2018-04-21

    Jasmonic acid (JA) has been mostly studied in responses to biotic stresses, such as herbivore attack and pathogenic infection. More recently, the involvement of JA in abiotic stresses including salinity was highlighted; yet, its role in salt stress remained unclear. In the current study, we compared the physiological and biochemical responses of wild-type (WT) tomato (Solanum lycopersicum) cv Castlemart and its JA-deficient mutant defenseless-1 (def-1) under salt stress to investigate the role of JA. Plant growth, photosynthetic pigment content, ion accumulation, oxidative stress-related parameters, proline accumulation and total phenolic compounds, in addition to both enzymatic and non-enzymatic antioxidant activities, were measured in both genotypes after 14 days of 100 mM NaCl treatment. Although we observed in both genotypes similar growth pattern and sodium, calcium and potassium levels in leaves under salt stress, def-1 plants exhibited a more pronounced decrease of nitrogen content in both leaves and roots and a slightly higher level of sodium in roots compared to WT plants. In addition, def-1 plants exposed to salt stress showed reactive oxygen species (ROS)-associated injury phenotypes. These oxidative stress symptoms in def-1 were associated with lower activity of both enzymatic antioxidants and non-enzymatic antioxidants. Furthermore, the levels of the non-enzymatic ROS scavengers proline and total phenolic compounds increased in both genotypes exposed to salt stress, with a higher amount of proline in the WT plants. Overall the results of this study suggest that endogenous JA mainly enhanced tomato salt tolerance by maintaining ROS homeostasis. Copyright © 2018 Elsevier GmbH. All rights reserved.

  18. Impulsivity and its relationship with anxiety, depression and stress.

    Science.gov (United States)

    Moustafa, Ahmed A; Tindle, Richard; Frydecka, Dorota; Misiak, Błażej

    2017-04-01

    We aimed to assess the association between depression, anxiety, stress and impulsivity with respect to age. The Depression, Anxiety and Stress Scale (DASS-42) and the Barratt Impulsiveness Scale (BIS-11) were administered to 145 individuals. Due to a negative correlation between age, BIS-11 and DASS-42 subscales, participants were divided into three groups: young-aged (18-30years), middle-aged (31-49years) and old-aged (≥50years). Subjects from old-aged group had significantly lower scores of depression, anxiety, stress and impulsivity compared to those from younger groups. Anxiety, followed by stress and depression, was the strongest predictor of BIS-11 total score in young-aged and middle-aged individuals. There were no significant differences in the correlations between BIS-11 total score, depression, anxiety and stress in old-aged individuals. Our results indicate that the levels of depression, anxiety, stress and impulsivity decrease with age. Additionally, age might moderate the effect of depression, anxiety and stress on impulsivity. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Serum total antioxidant capacity in patients with multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Almira Hadžović-Džuvo

    2011-02-01

    Full Text Available Multiple sclerosis (MS is a chronic inflammatory disease of the central nervous system (CNS. It is characterized by loss of myelin, the fatty tissue that surrounds and protects nerve fibres allowing them to conduct electrical impulses. Recent data indicate that oxidative stress (OS plays a major role in the pathogenesis of multiple sclerosis (MS. The aim of this study was to estimate level of serum total antioxidative capacity in patients with multiple sclerosis. Our cross-sectional study included 33 patients with MS and 24 age and sex matched control subjects. All our patients had a Poser criteria for definite diagnostic categories of multiple sclerosis. Serum total antioxidant capacity (TAC was measured by quantitative colorimetric determination, using Total antioxidant Capacity-QuantiCromAntioxidant Assay Kit (BioAssay systems, USA; DTAC-100. Mean serum TAC in multiple sclerosis group of patients was 119.2 mM Trolox equivalents and was significantly lower (p<0.001 compared to the control group of subjects (167.1 mM Trolox equivalents. Our results showed that oxidative stress plays an important role in pathogenesis of multiple sclerosis. This finding, also, suggests the importance of antioxidants in diet and therapy of MS patients.

  20. Structural study of α-Bi2O3 under pressure

    International Nuclear Information System (INIS)

    Pereira, A L J; Sans, J A; Manjón, F J; Errandonea, D; García-Domene, B; Miquel-Veyrat, A; Beltrán, A; Gracia, L; Gomis, O; Muñoz, A; Popescu, C

    2013-01-01

    An experimental and theoretical study of the structural properties of monoclinic bismuth oxide (α-Bi 2 O 3 ) under high pressures is here reported. Both synthetic and mineral bismite powder samples have been compressed up to 45 GPa and their equations of state have been determined with angle-dispersive x-ray diffraction measurements. Experimental results have been also compared with theoretical calculations which suggest the possibility of several phase transitions below 10 GPa. However, experiments reveal only a pressure-induced amorphization between 15 and 25 GPa, depending on sample quality and deviatoric stresses. The amorphous phase has been followed up to 45 GPa and its nature discussed. (paper)

  1. Standard practice for preparation and use of Bent-Beam stress-corrosion test specimens

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2011-01-01

    1.1 This practice covers procedures for designing, preparing, and using bent-beam stress-corrosion specimens. 1.2 Different specimen configurations are given for use with different product forms, such as sheet or plate. This practice applicable to specimens of any metal that are stressed to levels less than the elastic limit of the material, and therefore, the applied stress can be accurately calculated or measured (see Note 1). Stress calculations by this practice are not applicable to plastically stressed specimens. Note 1—It is the nature of these practices that only the applied stress can be calculated. Since stress-corrosion cracking is a function of the total stress, for critical applications and proper interpretation of results, the residual stress (before applying external stress) or the total elastic stress (after applying external stress) should be determined by appropriate nondestructive methods, such as X-ray diffraction (1). 1.3 Test procedures are given for stress-corrosion testing by ex...

  2. [Assessment of stress in childhood: Children's Daily Stress Inventory (Inventario Infantil de Estresores Cotidiano, IIEC)].

    Science.gov (United States)

    Trianes Torres, María Victoria; Blanca Mena, María José; Fernández Baena, Francisco J; Escobar Espejo, Milagros; Maldonado Montero, Enrique F; Muñoz Sánchez, Angela María

    2009-11-01

    The present study introduces the Children's Daily Stress Inventory (Inventario Infantil de Estresores Cotidianos, IIEC) as a measure that assesses daily stress in primary school children. The inventory was applied to a sample of 1094 primary school students. The final version includes 25 dichotomic items covering the areas of health, school/peers, and family. The score is obtained by adding the total of positive answers. Analyses of items, reliability and several external pieces of evidence of validity based on relations with other variables are presented. The results show adequate psychometric properties for the assessment of daily stress in children.

  3. Association of parental stress and early childhood caries

    Directory of Open Access Journals (Sweden)

    Seyed Ebrahim Jabbarifar

    2009-01-01

    Full Text Available Background:Little research has been carried out on whether the parental stress affects children′s oral health in general and dental caries in particular. This study aimed to investigate the association be-tween parental stress and early childhood caries (ECC. Methods: A cross-sectional study was designed that included 250 children of 4-6 year-old; 127 ones attended the pediatric department of Isfahan School of Dentistry who had early childhood caries and a comparison group of 123 caries free children attended five kindergartens and pre-schools in Isfahan city. Clinical examinations were conducted to evaluate the caries status. The parents of the two study groups completed the self-administrated long form of the Parenting Stress Index questionnaire. De-tails of their socio-demographic status were gathered too. The collected data were analyzed by SPSS version 11.5. The nonparametric Mantel-Haenszel test for correlation statistics was used to determine bivariate associations between total parenting stress and their domains scores in the two groups; i.e., those with early childhood caries and the caries free group. Results: Mean score of PSI in the early childhood caries and caries free group were 286.66 ± 66.26 and 273.87 ± 31.03, respectively. There was not any significant relationship between total parental stress and ECC. The scores of the following domains of PSI demonstrated significant differences between ECC and CF groups: child reinforcement, child distractibility, child deficit attention, life stress and relationship with spouse (P = 0.01, 0.01, 0.001, 0.005 respectively. Conclusion: Findings of this study did not show any significant association between total parenting stress score and prevalence of early childhood caries.

  4. Comparative Effects of Salt Stress and Extreme pH Stress Combined on Glycinebetaine Accumulation, Photosynthetic Abilities and Growth Characters of Two Rice Genotypes

    Directory of Open Access Journals (Sweden)

    Suriyan CHA-UM

    2009-12-01

    Full Text Available Glycinebetaine (Glybet accumulation, photosynthetic efficiency and growth performance in indica rice cultivated under salt stress and extreme pH stress were investigated. Betaine aldehyde dehydrogenase (BADH activity and Glybet accumulation in the seedlings of salt-tolerant and salt-sensitive rice varieties grown under saline and acidic conditions peaked after treatment for 72 h and 96 h, respectively, and were higher than those grown under neutral pH and alkaline salt stress. A positive correlation was found between BADH activity and Glybet content in both salt-tolerant (r2 = 0.71 and salt-sensitive (r2 = 0.86 genotypes. The chlorophyll a, chlorophyll b, total chlorophyll and total carotenoids contents in the stressed seedlings significantly decreased under both acidic and alkaline stresses, especially in the salt-sensitive genotype. Similarly, the maximum quantum yield of PSII (Fv/Fm, photon yield of PSII (ΦPSII, non-photochemical quenching (NPQ and net photosynthetic rate (Pn in the stressed seedlings were inhibited, leading to overall growth reduction. The positive correlations between chlorophyll a content and Fv/Fm, total chlorophyll content and ΦPSII, ΦPSII and Pn as well as Pn and leaf area in both salt-tolerant and salt-sensitive genotypes were found. Saline acidic and saline alkaline soils may play a key role affecting vegetative growth prior to the reproductive stage in rice plants.

  5. Overexpression of a cytosolic abiotic stress responsive universal stress protein (SbUSP mitigates salt and osmotic stress in transgenic tobacco plants

    Directory of Open Access Journals (Sweden)

    Pushpika eUdawat

    2016-04-01

    Full Text Available The Universal Stress Protein (USP is a ubiquitous protein and plays an indispensable role in plant abiotic stress tolerance. The genome of Salicornia brachiata contains two homologues of intron less SbUSP gene which encodes for salt and osmotic responsive universal stress protein. In vivo localization reveals that SbUSP is a membrane bound cytosolic protein. The role of the gene was functionally validated by developing transgenic tobacco and compared with control (wild type and vector control plants under different abiotic stress condition. Transgenic lines (T1 exhibited higher chlorophyll, relative water, proline, total sugar, reducing sugar, free amino acids, polyphenol contents, osmotic potential, membrane stability and lower electrolyte leakage and lipid peroxidation (malondialdehyde content under stress treatments than control (WT and VC plants. Lower accumulation of H2O2 and O2- radicals was also detected in transgenic lines compared to control plants under stress conditions. Present study confers that overexpression of the SbUSP gene enhances plant growth, alleviates ROS buildup, maintains ion homeostasis and improves the physiological status of the plant under salt and osmotic stresses. Principal component analysis (PCA exhibited a statistical distinction of plant response to salinity stress, and a significant response was observed for transgenic lines under stress, which provides stress endurance to the plant. A possible signaling role is proposed that some downstream genes may get activated by abiotic stress responsive cytosolic SbUSP, which leads to the protection of cell from oxidative damages. The study unveils that ectopic expression of the gene mitigates salt or osmotic stress by scavenging ROS and modulating the physiological process of the plant.

  6. Neuronal substrates underlying stress resilience and susceptibility in rats

    DEFF Research Database (Denmark)

    Febbraro, Fabia; Svenningsen, Katrine; Thao Phuong Tran

    2017-01-01

    attention has been devoted to understand resiliency to stress. The aim of the present study was to identify changes in neuronal activity, associated with stress-resilient and stress-susceptible chronic mild stress endophenotypes, by examining c-Fos expression in 13 different brain areas. Changes in c...... responses was done by semi-automated profile counting procedures and design-based stereology. RESULTS: Exposure to chronic mild stress significantly altered c-Fos expression in a total of 6 out of 13 investigated areas. Chronic mild stress was found to suppress the c-Fos response within the magnocellular...

  7. Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica

    Directory of Open Access Journals (Sweden)

    Quy Diem Do

    2014-09-01

    Full Text Available Limnophila aromatica is commonly used as a spice and a medicinal herb in Southeast Asia. In this study, water and various concentrations (50%, 75%, and 100% of methanol, ethanol, and acetone in water were used as solvent in the extraction of L. aromatica. The antioxidant activity, total phenolic content, and total flavonoid content of the freeze-dried L. aromatica extracts were investigated using various in vitro assays. The extract obtained by 100% ethanol showed the highest total antioxidant activity, reducing power and DPPH (2,2-diphenyl-1-picrylhydrazyl radical scavenging activity. The same extract also exhibited the highest phenolic content (40.5 mg gallic acid equivalent/g of defatted L. aromatica and the highest flavonoid content (31.11 mg quercetin equivalent/g of defatted L. aromatica. The highest extraction yield was obtained by using 50% aqueous acetone. These results indicate that L. aromatica can be used in dietary applications with a potential to reduce oxidative stress.

  8. Total Quality Management in Higher Education: Applying Deming's Fourteen Points.

    Science.gov (United States)

    Masters, Robert J.; Leiker, Linda

    1992-01-01

    This article presents guidelines to aid administrators of institutions of higher education in applying the 14 principles of Total Quality Management. The principles stress understanding process improvements, handling variation, fostering prediction, and using psychology to capitalize on human resources. (DB)

  9. On some features of the effective behaviour of porous solids with J2- and J3-dependent yielding matrix behaviour

    Science.gov (United States)

    Benallal, Ahmed

    2018-02-01

    Some features od the constitutive behaviour of voided materials taking into account possible effects of the Lode angle in the yielding behaviour of the matrix are discussed. The Gurson approach is used to this end. After providing a parametric representation of the effective behaviour of such materials, some closed-form results are given for pure shear stress states and also at very high stress triaxialities. In the former case corresponding to a zero macroscopic mean stress, the contour of the yield domain in the π-plane has exactly the shape of the yield surface of the matrix in the deviatoric plane, but a size reduced by a factor 1 - f, with f the porosity of the voided material. In the latter, effective yield stresses for the voided material are slightly different from the Gurson result and found to be set by the yield stress at a microscopic stress Lode angle π/3 for very high positive triaxiality and by the yield stress at a microscopic stress Lode angle 0 for very high negative triaxiality. This last result is extended for porous materials with yielding depending further on the hydrostatic stress, fully exhibiting the interaction between volumetric and shear interactions on the yielding behaviour of isotropic porous materials. Applications to many usual yielding criteria for the matrix are also provided. xml:lang="fr"

  10. Having your cake and eating it too: a habit of comfort food may link chronic social stress exposure and acute stress-induced cortisol hyporesponsiveness.

    Science.gov (United States)

    Tryon, M S; DeCant, Rashel; Laugero, K D

    2013-04-10

    Stress has been tied to changes in eating behavior and food choice. Previous studies in rodents have shown that chronic stress increases palatable food intake which, in turn, increases visceral fat and inhibits acute stress-induced hypothalamic-pituitary-adrenal (HPA) axis activity. The effect of chronic stress on eating behavior in humans is less understood, but it may be linked to HPA responsivity. The purpose of this study was to investigate the influence of chronic social stress and acute stress reactivity on food choice and food intake. Forty-one women (BMI=25.9±5.1 kg/m(2), age range=41 to 52 years) were subjected to the Trier Social Stress Test or a control task (nature movie) to examine HPA responses to an acute laboratory stressor and then invited to eat from a buffet containing low- and high-calorie snacks. Women were also categorized as high chronic stress or low chronic stress based on Wheaton Chronic Stress Inventory scores. Women reporting higher chronic stress and exhibiting low cortisol reactivity to the acute stress task consumed significantly more calories from chocolate cake on both stress and control visits. Chronic stress in the low cortisol reactor group was also positively related to total fat mass, body fat percentage, and stress-induced negative mood. Further, women reporting high chronic stress consumed significantly less vegetables, but only in those aged 45 years and older. Chronic stress in women within the higher age category was positively related to total calories consumed at the buffet, stress-induced negative mood and food craving. Our results suggest an increased risk for stress eating in persons with a specific chronic stress signature and imply that a habit of comfort food may link chronic social stress and acute stress-induced cortisol hyporesponsiveness. Published by Elsevier Inc.

  11. Primary teachers' knowledge and acquisition of stress relieving strategies.

    Science.gov (United States)

    Cockburn, A D

    1996-09-01

    Over the last 20 years there have been numerous studies of teacher stress but little is known of how teachers acquire coping strategies; their knowledge of those available to them and their opinion of these techniques. A total of 335 Norfolk primary teachers responded to a postal questionnaire providing biographical details; levels of job satisfaction and work related stress; responses to a range of commonly advocated techniques to reduce teacher stress and their opinion on who-if anyone-should take more responsibility for reducing teacher stress. On average the respondents were aware of 35 stress reduction strategies. The most effective strategies were ensuring that one understood what one was about to teach and thorough lesson preparation. A significant proportion of practitioners said that they would not consider seeking expert sources of advice. A total of 89 per cent of practitioners reported that they acquired at least some strategies through their own experience. It was concluded that the issue of teacher stress needs to be considered at governmental, school and individual levels. In the light of some resistance to traditional methods of stress reduction, the implications for initial and in-service training were explored.

  12. Microseismic Monitoring of the Olivine → Spinel Transition in Fayalite Under Non-Hydrostatic Stress

    Science.gov (United States)

    Officer, T.; Secco, R. A.

    2016-12-01

    In subduction zones, deep earthquakes are thought to be associated with faulting that arises from phase transformations. In order to test the viability of this mechanism experimentally, it is necessary to make microseismic measurements while the mineral under investigation is subjected to the pressure and temperature (P,T) environment at depth. A system has been developed capable of making in situ acoustic emission (AE) measurements on samples under P,T conditions representative of the upper mantle and transition zone. Experiments are performed in a 3000-ton multi-anvil press using an 18/11 octahedral cell with 6 piezoelectric transducers mounted on the rear side of the anvils. AE signals are collected at a sampling rate of 40 MHz using a triggered system and a data buffer for continuous recording so full waveforms of AE events are captured. The use of multiple transducers distributed in a microseismic array allows for events to be located within the sample through automatic arrival time picking and least squares inversion techniques. The multi-anvil apparatus constitutes an inherently noisy environment both acoustically and electrically, therefore methods of noise reduction were developed and will be discussed. This technique has been used to measure acoustic signals generated from the fracturing of quartz beads during high pressure deformation and to investigate the possibility that the phase transformation from olivine to spinel, known to occur in subduction zones, is associated with deep-focus earthquakes (300 - 690 km depth). The analog material fayalite (Fe2SiO4), the iron end member of olivine, has been examined. Information about its synthesis and sintering will be discussed as well as results of AE experiments on samples experiencing deviatoric stress under high pressure (P = 4-9 GPa) and high temperature (T = 773-1273 K) conditions in the spinel stability field.

  13. Pressure pain sensitivity as a marker for stress and pressure pain sensitivity-guided stress management in women with primary breast cancer

    DEFF Research Database (Denmark)

    Axelsson, Christen K; Ballegaard, Søren; Karpatschof, Benny

    2014-01-01

    employees was divided in a High Stress Group (HSG, n = 37) and a Low Stress Group (LSG, n = 128) to evaluate the association between PPS, questionnaire-related Quality of Life (QOL) and self-evaluated stress. (2) A PPS-guided stress management program (n = 40) was compared to a Psychosocial Group......OBJECTIVES: To validate (1) Pressure Pain Sensitivity (PPS) as a marker for stress and (2) a PPS-guided intervention in women with primary Breast Cancer (BC). METHODS: (1) A total of 58 women with BC were examined before and after 6 months of intervention. A control group of 165 women office...... scores: (all p stress scores (all p

  14. Reduced total serum bilirubin levels are associated with ulcerative colitis.

    Directory of Open Access Journals (Sweden)

    Kathleen M Schieffer

    Full Text Available Chronic inflammation associated with inflammatory bowel disease (IBD results in increased oxidative stress that damages the colonic microenvironment. Low levels of serum bilirubin, an endogenous antioxidant, have been associated with increased risk for Crohn's disease (CD. Therefore, the aim of this study was to examine whether total serum bilirubin levels are associated with ulcerative colitis (UC. We identified a retrospective case-control population (n = 6,649 from a single tertiary care center, Penn State Hershey Medical Center (PSU and a validation cohort (n = 1,996 from Virginia Commonwealth University Medical Center (VCU. Cases were age- and sex-matched to controls (PSU: CD n = 254, UC n = 187; VCU: CD n = 233, UC n = 124. Total serum bilirubin levels were obtained from de-identified medical records and segregated into quartiles. Logistic regression analysis was performed on each quartile of total serum bilirubin compared to the last quartile (highest bilirubin levels to determine the association of total serum bilirubin with UC. Similar to CD patients, UC patients demonstrated reduced levels of total serum bilirubin compared to controls at PSU and VCU. The lowest quartile of total serum bilirubin was independently associated with UC for the PSU (OR: 1.98 [95% CI: 1.09-3.63] and VCU cohorts (OR: 6.07 [95% CI: 3.01-12.75]. Lower levels of the antioxidant bilirubin may reduce the capability of UC patients to remove reactive oxygen species leading to an increase in intestinal injury. Therapeutics that reduce oxidative stress may be beneficial for these patients.

  15. Fully porous 3D printed titanium femoral stem to reduce stress-shielding following total hip arthroplasty.

    Science.gov (United States)

    Arabnejad, Sajad; Johnston, Burnett; Tanzer, Michael; Pasini, Damiano

    2017-08-01

    Current hip replacement femoral implants are made of fully solid materials which all have stiffness considerably higher than that of bone. This mechanical mismatch can cause significant bone resorption secondary to stress shielding, which can lead to serious complications such as peri-prosthetic fracture during or after revision surgery. In this work, a high strength fully porous material with tunable mechanical properties is introduced for use in hip replacement design. The implant macro geometry is based off of a short stem taper-wedge implant compatible with minimally invasive hip replacement surgery. The implant micro-architecture is fine-tuned to locally mimic bone tissue properties which results in minimum bone resorption secondary to stress shielding. We present a systematic approach for the design of a 3D printed fully porous hip implant that encompasses the whole activity spectrum of implant development, from concept generation, multiscale mechanics of porous materials, material architecture tailoring, to additive manufacturing, and performance assessment via in vitro experiments in composite femurs. We show that the fully porous implant with an optimized material micro-structure can reduce the amount of bone loss secondary to stress shielding by 75% compared to a fully solid implant. This result also agrees with those of the in vitro quasi-physiological experimental model and the corresponding finite element model for both the optimized fully porous and fully solid implant. These studies demonstrate the merit and the potential of tuning material architecture to achieve a substantial reduction of bone resorption secondary to stress shielding. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1774-1783, 2017. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  16. Overexpression of a Cytosolic Abiotic Stress Responsive Universal Stress Protein (SbUSP) Mitigates Salt and Osmotic Stress in Transgenic Tobacco Plants

    Science.gov (United States)

    Udawat, Pushpika; Jha, Rajesh K.; Sinha, Dinkar; Mishra, Avinash; Jha, Bhavanath

    2016-01-01

    The universal stress protein (USP) is a ubiquitous protein and plays an indispensable role in plant abiotic stress tolerance. The genome of Salicornia brachiata contains two homologs of intron less SbUSP gene which encodes for salt and osmotic responsive USP. In vivo localization reveals that SbUSP is a membrane bound cytosolic protein. The role of the gene was functionally validated by developing transgenic tobacco and compared with control [wild-type (WT) and vector control (VC)] plants under different abiotic stress condition. Transgenic lines (T1) exhibited higher chlorophyll, relative water, proline, total sugar, reducing sugar, free amino acids, polyphenol contents, osmotic potential, membrane stability, and lower electrolyte leakage and lipid peroxidation (malondialdehyde content) under stress treatments than control (WT and VC) plants. Lower accumulation of H2O2 and O2− radicals was also detected in transgenic lines compared to control plants under stress conditions. Present study confers that overexpression of the SbUSP gene enhances plant growth, alleviates ROS buildup, maintains ion homeostasis and improves the physiological status of the plant under salt and osmotic stresses. Principal component analysis exhibited a statistical distinction of plant response to salinity stress, and a significant response was observed for transgenic lines under stress, which provides stress endurance to the plant. A possible signaling role is proposed that some downstream genes may get activated by abiotic stress responsive cytosolic SbUSP, which leads to the protection of cell from oxidative damages. The study unveils that ectopic expression of the gene mitigates salt or osmotic stress by scavenging ROS and modulating the physiological process of the plant. PMID:27148338

  17. Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats.

    Science.gov (United States)

    Su, Jing; Zhang, Pei; Zhang, Jing-Jing; Qi, Xiang-Ming; Wu, Yong-Gui; Shen, Ji-Jia

    2010-03-01

    TGP, extracted from the traditional Chinese herb root of Paeonia lactiflora pall, has been shown to have therapeutic effect in experimental diabetic nephropathy. However, its mechanism is not fully understood. In this study, the effects of TGP on oxidative stress were investigated in the kidney of diabetic rats induced by streptozotocin. TGP (50, 100, 200mg/kg) was orally administered once a day for 8 weeks. TGP treatment in all three doses significantly lowered 24 h urinary albumin excretion rate in diabetic rats and attenuated glomerular volume. TGP treatment with 100 and 200mg/kg significantly reduced indices for tubulointerstitial injury in diabetic rats. The level of MDA was significantly increased in the kidney of diabetic rats and attenuated by TGP treatment at the dose of 200mg/kg. TGP treatment in a dose-dependent manner decreased the level of 3-NT protein of the kidney which increased under diabetes. T-AOC was significantly reduced in diabetic rat kidney and remarkably increased by TGP treatment at the dose of 100 and 200mg/kg. Activity of antioxidant enzyme such as SOD, CAT was markedly elevated by TGP treatment with 200mg/kg. Western blot analysis showed that p-p38 MAPK and NF-kappaB p65 protein expression increased in diabetic rat kidney, which were significantly decreased by TGP treatment. It seems likely that oxidative stress is increased in the diabetic rat kidneys, while TGP can prevent diabetes-associated renal damage against oxidative stress.

  18. Effect of stress on serum cholestrol levels in nurses and housewives of Hyderabad - Pakistan

    International Nuclear Information System (INIS)

    Watto, F.H.; Memon, M.S.; Memon, A.N.; Ghanghro, A.B.; Yaquib, M.; Watto, M.H.S.; Tirmizi, S.A.

    2010-01-01

    A cohort type study was designed to evaluate environmental, psychological and physiological stresses in nurses and housewives and to correlate with their serum total cholesterol, HDL cholesterol, LDL cholesterol and triglyceride levels. Total 160 females from middle socioeconomic groups (nurses, n=80 and housewives, n=80) aged between 25-45 years participated in this study and subjects were selected from Hyderabad and its adjoining areas. Environmental, psychological and physiological stress levels were measured with likert scale. Total cholesterol, LDL cholesterol and HDL cholesterol were measured by CHOD-PAP method and triglyceride levels were measured by GPO method. Housewives were found to have high levels of total cholesterol, LDL cholesterol and triglycerides. The HDL cholesterol were lower. Environmental, psychological and physiological stresses were significantly higher in housewives as compared to the nurses. Highest level of environmental stress was observed in nonworking group i.e. housewives. A significant relation between serum cholesterol levels and three types of stresses was observed. (author)

  19. Effect of liquid sodium thermochemical reactions with stainless steels on mechanical response

    International Nuclear Information System (INIS)

    Subbaraman, G.; Reifsnider, K.L.

    1976-01-01

    An analytical approach is presented to study the elastic response of an LMFBR fuel clad subject to strong property degradation in liquid sodium environment and internal poison pressure, at the gas plenum section of the fuel pin. The nature and analysis of the thermochemical reactions and the available experimental data are briefly reviewed. Property variations in the radial direction due to these inservice reactions are represented by a generalized, continuous function, f(r), which is introduced into the constitutive equations of stress equilibrium. By introducing an adjustable constant A into a specific form of f(r), various severities in the variation of the elastic parameters through the thickness of the clad are accommodated and particular analytical solutions are obtained for the displacement. Closed form solutions, which are available for particular values of A, are used as validity checks in computing the more general solutions. The stress-strain responses including the deviatoric stresses used in creep analyses are presented for several cases. The merits of the analytical formulation of the problem and the need to include similar approaches in fuel performance calculations are stated

  20. Experimental evidence for stress enhanced swelling

    International Nuclear Information System (INIS)

    Bates, J.F.; Gilbert, E.R.

    1976-01-01

    Experimental evidence is presented which shows that the application of a biaxial stress during irradiation can increase the magnitude of irradiation-induced swelling observed in tubular specimens. It is shown that this increase in swelling is linear below the proportional elastic limit of the material and decreases above this value of stress. In the linear region a relationship is found between total swelling and stress free swelling. The phenomenon of reduced swelling is evaluated on the basis of increased cold work due to pre-irradiation straining. This analysis yields a relationship of dislocation density proportional to stress to the 3.82 power. Additional analyses using dislocation density proportional to sigma 2 (sigma = hoop stress) yield a similar but sharper decrease in swelling after the proportional elastic limit is reached. (Auth.)

  1. Total Water Management, the New Paradigm for Urban Water Systems

    Science.gov (United States)

    There is a growing need for urban water managers to take a more holistic view of their water resource systems as population growth, urbanization, and current resource management practices put different stresses on local water resources and urban infrastructure. Total Water Manag...

  2. Effect of stress on serum lipid levels in lady health visitors and housewives

    International Nuclear Information System (INIS)

    Wattoo, F.H.; Memon, M.S.; Memon, A.N.; Wattoo, M.H.S.; Tirmizi, S.A.; Iqbal, J.

    2007-01-01

    To study the effects of stress among lady health visitors and housewives in regard to their serum total cholesterol, HDL cholesterol, and LDL cholesterol and triglyceride levels. The study was performed at the Institute of Biochemistry, University of Sindh, Jamshoro, Pakistan during the years 2003 to 2005. Seventy lady health visitor and housewives aged between 25-40 years participated in this study and were selected from Hyderabad and its adjoining areas. Environmental, psychological and physiological stress levels were measured with likert scale. Total cholesterol, LDL cholesterol and HDL cholesterol and triglyceride levels were measured. Environmental, psychological and physiological stresses were significantly higher in housewives as compared to lady health visitors. A low level of HDL cholesterol was observed in housewives as compared to lady health visitors. The levels of total cholesterol, LDL cholesterol and triglyceride were found higher in housewives than lady health visitors. Housewives are under more stress than lady health visitors. The levels of total cholesterol, LDL cholesterol and triglyceride increases but HDL cholesterol decrease with stress. (author)

  3. Decrease of total antioxidant capacity during coronary artery bypass surgery.

    Science.gov (United States)

    Kunt, Alper Sami; Selek, Sahbettin; Celik, Hakim; Demir, Deniz; Erel, Ozcan; Andac, Mehmet Halit

    2006-09-01

    Cardiac surgery induces an oxidative stress, which may lead to impairment of cardiac function. In this study, we aimed to measure the changes of oxidative and antioxidative status of patients undergoing coronary artery bypass surgery (CABG). We studied 79 patients who underwent CABG with and without cardiopulmonary bypass (CPB). Of the 79 patients, 39 had CPB and 40 did not. Blood samples were drawn before, during, and after the surgery. Antioxidant status was evaluated by measuring total antioxidant capacity (TAC), and oxidative status was evaluated by measuring total peroxide (TP) levels and oxidative stress index (OSI). TP and OSI levels increased, while TAC decreased progressively after the beginning of surgery, for all patients. There were negative correlations between TAC levels and aortic cross-clamping period and anastomosis time ( r = -0.553, p antioxidant vitamins such as vitamins C and E may be beneficial for patients undergoing CABG.

  4. Relationship between Occupational Stress and Gastric Disease in Male Workers.

    Science.gov (United States)

    Lihm, Ho-Seob; Park, Sang-Hyun; Gong, Eun-Hee; Choi, Jong-Soon; Kim, Jung-Won

    2012-09-01

    Physical and mental health of workers is threatened due to various events and chronic occupational stress. This study was conducted to investigate the relationship between occupational stress and gastric disease in male workers of the shipbuilding industry. Occupational stress measured among a total of 498 workers of a shipbuilding firm who visited the hospital for health examination using the Korean Occupational Stress Scale (KOSS)-short form, and the relationship between sociodemographic factors, health-related behaviors, occupational stress, and gastric disease, and the distribution of occupational stress by sociodemographic factors in the gastric disease group was examined. There was no significant association between gastric disease and total occupational stress score and its seven sub-factors. The analysis showed that risk of gastric disease was significantly higher in the Q1 group in which the stress caused by occupational discomfort among seven sub-factors was lowest than that in the Q4 group (odds ratio, 2.819; 95% confidence interval, 1.151 to 6.908). Analysis only on the gastric disease group showed that the stress score of laborers was higher in the four sub-factors than that of office workers (P occupational stress in the low-educated and laborers. It is recommended for future studies to confirm the causal relationship between occupational stress and gastric disease by large scale studies using a KOSS which appropriately reflects workplace culture.

  5. Statistical damage constitutive model for rocks subjected to cyclic stress and cyclic temperature

    Science.gov (United States)

    Zhou, Shu-Wei; Xia, Cai-Chu; Zhao, Hai-Bin; Mei, Song-Hua; Zhou, Yu

    2017-10-01

    A constitutive model of rocks subjected to cyclic stress-temperature was proposed. Based on statistical damage theory, the damage constitutive model with Weibull distribution was extended. Influence of model parameters on the stress-strain curve for rock reloading after stress-temperature cycling was then discussed. The proposed model was initially validated by rock tests for cyclic stress-temperature and only cyclic stress. Finally, the total damage evolution induced by stress-temperature cycling and reloading after cycling was explored and discussed. The proposed constitutive model is reasonable and applicable, describing well the stress-strain relationship during stress-temperature cycles and providing a good fit to the test results. Elastic modulus in the reference state and the damage induced by cycling affect the shape of reloading stress-strain curve. Total damage induced by cycling and reloading after cycling exhibits three stages: initial slow increase, mid-term accelerated increase, and final slow increase.

  6. Person-environment fit: using commensurate scales to predict student stress.

    Science.gov (United States)

    Puccio, G J; Talbot, R J; Joniak, A J

    1993-11-01

    The relationship between person-environment fit and stress was examined for two samples of university students (N = 55 and 79). The Kirton Adaption-Innovation Inventory (KAI) was modified to assess the students' perceptions of the adaptor-innovator style required by their course, the styles they exhibited in the course, and their ideal style preferences. To ascertain fit, the KAI total scores and subscale scores (Originality, Efficiency, and Rule/Group Conformity) were used to classify students on three dimensions: (1) perception of what style their course required, adaptive or innovative; (2) congruence between the style the course required and the style they exhibited in the course; and (3) the magnitude of the difference, if any, between the required style and the exhibited style. Points two and three are measures of fit. The dependent variable was stress. Also the students' ideal style scores, KAI total and subscales, were substituted for the exhibited scores and the classification and analyses were repeated. Analysis of the total scores revealed that a course requiring adaptive behaviours was perceived as more stressful than a course requiring innovative behaviours. Similarly, an analysis of the Rule/Group Conformity scores revealed that the greater the conformity required the greater the stress. Also the less originality demanded in the course the greater was the perceived stress. For the KAI total scores and Rule/Group Conformity scores, the two measures of fit (incongruity and magnitude of the incongruity) were not related to stress. However, analyses of the Originality and Efficiency subscales supported the importance of the P-E fit position. For both subscales, stress was associated with the magnitude of the difference between what was required in the course and what students exhibited in the course. Educational implications derived from these findings as well as recommendations for future research are discussed.

  7. Finite element calculation of stress induced heating of superconductors

    International Nuclear Information System (INIS)

    Akin, J.E.; Moazed, A.

    1976-01-01

    This research is concerned with the calculation of the amount of heat generated due to the development of mechanical stresses in superconducting composites. An emperical equation is used to define the amount of stress-induced heat generation per unit volume. The equation relates the maximum applied stress and the experimental measured hysteresis loop of the composite stress-strain diagram. It is utilized in a finite element program to calculate the total stress-induced heat generation for the superconductor. An example analysis of a solenoid indicates that the stress-induced heating can be of the same order of magnitude as eddy current effects

  8. Psychosocial Stress Among Patients With Type 2 Diabetes: Habitual ...

    African Journals Online (AJOL)

    USER

    A total of 193 adults with type 2 diabetes took part in this study. Psychosocial stress was ... KEY WORDS: Type 2 diabetes, psychosocial stress, habitual physical activity. INTRODUCTION ..... to address them: A qualitative study. PLoS ONE 9(9):.

  9. Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats

    Directory of Open Access Journals (Sweden)

    Xufeng Tao

    2016-07-01

    Full Text Available The effects of total flavonoids (TFs from Rosa laevigata Michx fruit against liver damage and cerebral ischemia/reperfusion (I/R injury have been reported, but its action on hepatic I/R injury remains unknown. In this work, the effects and possible mechanisms of TFs against hepatic I/R injury were examined using a 70% partial hepatic warm ischemia rat model. The results demonstrated TFs decreased serum aspartate transaminase (AST, alanine aminotransferase (ALT, myeloperoxidase (MPO, and lactate dehydrogenase (LDH activities, improved liver histopathology and ultrastructure through hematoxylin-eosin (HE staining and electron microscope observation. In addition, TFs significantly decreased malondialdehyde (MDA and increased the levels of superoxide dismutase (SOD and glutathione peroxidase (GSH-Px, which indicated that TFs alleviated oxidative stress caused by I/R injury. RT-PCR results proved that TFs downregulated the gene levels of inflammatory factors including interleukin-1 beta (IL-1β, interleukin-1 (IL-6, and tumor necrosis factor alpha (TNF-α. Further research indicated that TF-induced hepatoprotection was completed through inhibiting TLR4/MyD88 and activating Sirt1/Nrf2 signaling pathways. Blockade of the TLR4 pathway by TFs inhibited NF-κB and AP-1 transcriptional activities and inflammatory reaction. Activation of Sirt1/Nrf2 pathway by TFs increased the protein levels of HO-1 and GST to improve oxidative stress. Collectively, these findingsconfirmed the potent effects of TFs against hepatic I/R injury, which should be developed as a candidate for the prevention of this disease.

  10. On generalization uniaxial stress-strain relation

    International Nuclear Information System (INIS)

    Sahay, C.; Dubey, R.N.

    1980-01-01

    Different forms of constitutive relations have been advanced for elastic, plastic and elastic-plastic behaviour of materials. It is shown that the various forms of the stress-strain relationship are specialized forms of generalization of a single stress-strain relation. For example, it is shown how the laws of elastic deformation, and the incremental and total deformation relationship for plastic behaviour are derivable from the Ramberg-Osgood relation. (orig.)

  11. Perceived Stress Is Differentially Related to Hippocampal Subfield Volumes among Older Adults.

    Directory of Open Access Journals (Sweden)

    Molly E Zimmerman

    Full Text Available Chronic exposure to stress has been shown to impact a wide range of health-related outcomes in older adults. Despite extensive animal literature revealing deleterious effects of biological markers of stress on the dentate gyrus subfield of the hippocampus, links between hippocampal subfields and psychological stress have not been studied in humans. This study examined the relationship between perceived stress and hippocampal subfield volumes among racially/ethnically diverse older adults.Between July 2011 and March 2014, 116 nondemented participants were consecutively drawn from the Einstein Aging Study, an ongoing community-based sample of individuals over the age of 70 residing in Bronx, New York. All participants completed the Perceived Stress Scale, Geriatric Depression Scale, and underwent 3.0 T MRI. FreeSurfer was used to derive total hippocampal volume, hippocampal subfield volumes (CA1, CA2/CA3, CA4/Dentate Gyrus (CA4/DG, and subiculum, entorhinal cortex volume, whole brain volume, and total intracranial volume.Linear regression analyses revealed that higher levels of perceived stress were associated with smaller total hippocampal volume (β = -0.20, t = -2.40, p = 0.02, smaller CA2/CA3 volumes (β = -0.18, t = -2.24, p = 0.03 and smaller CA4/DG volumes (β = -0.19, t = -2.28, p = 0.03 after controlling for total intracranial volume, age, gender, and race. These findings remained unchanged after removal of individuals with clinically significant symptoms of depression.Our findings provide evidence of a relationship between a direct indicator of psychological stress and specific hippocampal subfield volumes in elderly individuals. These results highlight the importance of clinical screening for chronic stress in otherwise healthy older adults.

  12. Effect of hemodialysis on total antioxidant status of chronic renal ...

    African Journals Online (AJOL)

    Background: Renal failure is accompanied by oxidative stress, which is caused by enhanced production of reactive oxygen species and impaired antioxidant defense. Aim: To assess the effect of hemodialysis (by cellulose membrane dialyzer) on plasma total antioxidant status and lipid peroxidation of patients in chronic ...

  13. Psychological stress-relieving effects of chewing - Relationship between masticatory function-related factors and stress-relieving effects.

    Science.gov (United States)

    Tasaka, Akinori; Kikuchi, Manaki; Nakanishi, Kousuke; Ueda, Takayuki; Yamashita, Shuichiro; Sakurai, Kaoru

    2018-01-01

    The objective of the present study was to investigate the relationship between masticatory function-related factors (masticatory performance, occlusal contact area, maximum bite force, number of chewing strokes, and muscle activity) and the stress-relieving effects of chewing. A total of 28 healthy male subjects were instructed to rest or chew for 10min after 30min of stress loading with arithmetic calculations. Their stress state was assessed by measuring salivary cortisol levels. Saliva was collected at three time points: before stress loading, immediately after stress loading, and 10min after stress loading. Compared to resting, chewing produced a significantly greater reduction in the rate of change in salivary cortisol levels 10min after stress loading. A negative correlation was observed between the rate of decrease in salivary cortisol levels and the number of chewing strokes. No significant correlation was observed between the rate of decrease in salivary cortisol levels and other measurement items. In healthy dentulous people, the number of chewing strokes has been shown to be a masticatory function-related factor that affects stress relief from chewing, suggesting the possibility that more appropriate chewing would produce a greater effect psychological stress relief. Copyright © 2017 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  14. MODIFIED TECHNIQUE OF TOTAL LARYNGECTOMY

    Directory of Open Access Journals (Sweden)

    Predrag Spirić

    2010-12-01

    Full Text Available Surgical technique of total laryngectomy is well presented in many surgical textbooks. Essentially, it has remained the same since Gluck an Soerensen in 1922 described all its details. Generally, it stresses the U shape skin incision with releasing laryngeal structures and removing larynx from up to down. Further, pharyngeal reconstruction is performed with different kinds of sutures in two or more layers and is finished with skin suture and suction drainage. One of worst complications following this surgery is pharyngocutaneous fistula (PF. Modifications proposed in this this article suggests vertical skin incision with larynx removal from below upwards. In pharyngeal reconstruction we used the running locked suture in submucosal plan with „tobacco sac“ at the end on the tongue base instead of traditional T shaped suture. Suction drains were not used.The aim of study was to present the modified surgical technique of total laryingectomy and its impact on hospital stay duration and pharyngocutanous fistula formation. In this randomized study we analyzed 49 patients operated with modified surgical technique compared to 49 patient operated with traditional surgical technique of total laryngectomy. The modified technique of total laryngectomy was presented. Using modified technique we managed to decrease the PF percentage from previous 20,41% to acceptable 8,16% (p=0,0334. Also, the average hospital stay was shortened from 14,96 to 10,63 days (t =-2.9850; p=0.0358.The modified technique of total laryngectomy is safe, short and efficient surgical intervention which decreases the number of pharyngocutaneos fistulas and shortens the hospital stay.

  15. Study on the serum oxidative stress status in silicosis patients

    African Journals Online (AJOL)

    Administrator

    2011-09-07

    Sep 7, 2011 ... oxidative stress parameters were investigated in silicosis patients and controls group. 128 silicosis ... to help clinicians to further delineate the role of oxidative- stress .... in age, working duration smoking, total cholesterol, ALT,.

  16. Relationship between Occupational Stress and Gastric Disease in Male Workers

    Science.gov (United States)

    Lihm, Ho-Seob; Park, Sang-Hyun; Gong, Eun-Hee; Kim, Jung-Won

    2012-01-01

    Background Physical and mental health of workers is threatened due to various events and chronic occupational stress. This study was conducted to investigate the relationship between occupational stress and gastric disease in male workers of the shipbuilding industry. Methods Occupational stress measured among a total of 498 workers of a shipbuilding firm who visited the hospital for health examination using the Korean Occupational Stress Scale (KOSS)-short form, and the relationship between sociodemographic factors, health-related behaviors, occupational stress, and gastric disease, and the distribution of occupational stress by sociodemographic factors in the gastric disease group was examined. Results There was no significant association between gastric disease and total occupational stress score and its seven sub-factors. The analysis showed that risk of gastric disease was significantly higher in the Q1 group in which the stress caused by occupational discomfort among seven sub-factors was lowest than that in the Q4 group (odds ratio, 2.819; 95% confidence interval, 1.151 to 6.908). Analysis only on the gastric disease group showed that the stress score of laborers was higher in the four sub-factors than that of office workers (P occupational stress in the low-educated and laborers. It is recommended for future studies to confirm the causal relationship between occupational stress and gastric disease by large scale studies using a KOSS which appropriately reflects workplace culture. PMID:23115706

  17. Temperature and stress calculation for final disposal

    International Nuclear Information System (INIS)

    Tarandi, T.

    1979-02-01

    Temperature and stress distribution in and around the final storage facility has been calculated for three different arrangements of the tunnels: - 2 planes with 60 m vertical distance between them - 2 planes with 100 m distance and - 1 plane. The highest temperatures and stresses occur for the 2 plane alternative with distance 60 m between planes. The maximum compressive stress is in this case 24.0 MPa 140 years after the time of deposition, compared with 12.6 MPa in the 1 plane case. The maximum tensile stress exists at the surface and is in the 2 plane case 6.0 MPa 800 - 1,500 years after deposition, compared with 4.2 MPa for the 1 plane variant. An estimation of maximum tensile stresses between the tunnel planes yields a value of 1.5 MPa. The above-mentioned stresses are due to temperature distribution induced by the radioactive waste. To obtain the total stresses, initial stresses in the undisturbed rock, which vary according to location, are to be added to these stresses. (author)

  18. Probing Earth's State of Stress

    Science.gov (United States)

    Delorey, A. A.; Maceira, M.; Johnson, P. A.; Coblentz, D. D.

    2016-12-01

    The state of stress in the Earth's crust is a fundamental physical property that controls both engineered and natural systems. Engineered environments including those for hydrocarbon, geothermal energy, and mineral extraction, as well those for storage of wastewater, carbon dioxide, and nuclear fuel are as important as ever to our economy and environment. Yet, it is at spatial scales relevant to these activities where stress is least understood. Additionally, in engineered environments the rate of change in the stress field can be much higher than that of natural systems. In order to use subsurface resources more safely and effectively, we need to understand stress at the relevant temporal and spatial scales. We will present our latest results characterizing the state of stress in the Earth at scales relevant to engineered environments. Two important components of the state of stress are the orientation and magnitude of the stress tensor, and a measure of how close faults are to failure. The stress tensor at any point in a reservoir or repository has contributions from both far-field tectonic stress and local density heterogeneity. We jointly invert seismic (body and surface waves) and gravity data for a self-consistent model of elastic moduli and density and use the model to calculate the contribution of local heterogeneity to the total stress field. We then combine local and plate-scale contributions, using local indicators for calibration and ground-truth. In addition, we will present results from an analysis of the quantity and pattern of microseismicity as an indicator of critically stressed faults. Faults are triggered by transient stresses only when critically stressed (near failure). We show that tidal stresses can trigger earthquakes in both tectonic and reservoir environments and can reveal both stress and poroelastic conditions.

  19. Effects of l-carnitine on oxidative stress parameters in ...

    African Journals Online (AJOL)

    Emel Peri Canbolat

    2016-08-10

    Aug 10, 2016 ... Nitric oxide (NO), malondialdehyde (MDA), total antioxidant status (TAS), total oxidative stress .... Erel's method was used for measuring TOS.19 TOS was ..... antioxidant capacity using a new generation, more stable ABTS.

  20. Communication Patterns and Stress in the Preschool: An Observational Study

    Science.gov (United States)

    Sjödin, Fredrik; Neely, Gregory

    2017-01-01

    The study included 12 preschool departments, with two teachers in six departments characterised by high levels of stress and burnout and two teachers in six departments characterised by low levels of stress and burnout. A total of 24 females with a mean age of 43.5 years participated in the study. The teachers rated stress, fatigue, work demands…

  1. Mechanical behavior of New Mexico rock salt in triaxial compression up to 2000C

    International Nuclear Information System (INIS)

    Wawersik, W.R.; Hannum, D.W.

    1978-01-01

    An extensive experimental program is being conducted to determine the mechanical behavior of New Mexico rock salt in support of the structural design of a Radioactive Waste Isolation Pilot Plant (WIPP). In this initial report, three groups of tests are discussed to identify the relative and site-specific importance of deviator stress, confining pressure (mean stress), temperature, time (loading rate), and stress path. The three groups of experiments consist of (1) hydrostatic loading, (2) conventional triaxial compression tests (sigma 1 > sigma 2 = sigma 3 = const.), and (3) variable stress path tests including experiments at approximately constant sigma 1 and at constant mean stress. All data were generated on 100 mm diameter specimens. The rock salt exhibited nonlinear response under all loading conditions, practically zero initial elastic limit and an apparent inseparability of permanent deformations into time-independent and time-dependent components. Pressure and temperature did not alter the elastic constants but affected the principal strain ratio, the ratio volumetric strain/shear strain, rock salt ductility, and the ultimate stress. In particular, low pressure and temperature permitted pronounced dilatancy and loss in load bearing ability. Under such conditions the volumetric strains reach sizable fractions of the shear strains. Pressure remained important even at high temperature because it influenced the rate of shearing. Load path and stress history may be significant under deviatoric loading conditions and for large variations in pressure

  2. Characterization of the constitutive behavior of municipal solid waste considering particle compressibility.

    Science.gov (United States)

    Lü, Xilin; Zhai, Xinle; Huang, Maosong

    2017-11-01

    This paper presents a characterization of the mechanical behavior of municipal solid waste (MSW) under consolidated drained and undrained triaxial conditions. The constitutive model was established based on a deviatoric hardening plasticity model. A power form function and incremental hyperbolic form function were proposed to describe the shear strength and the hardening role of MSW. The stress ratio that corresponds to the zero dilatancy was not fixed but depended on mean stress, making the Rowe's rule be able to describe the stress-dilatancy of MSW. A pore water pressure reduction coefficient, which attributed to the compressibility of a particle and the solid matrix, was introduced to the effective stress formulation to modify the Terzaghi's principle. The effects of particle compressibility and solid matrix compressibility on the undrained behavior of MSW were analyzed by parametric analysis, and the changing characteristic of stress-path, stress-strain, and pore-water pressure were obtained. The applicability of the proposed model on MSW under drained and undrained conditions was verified by model predictions of three triaxial tests. The comparison between model simulations and experiments indicated that the proposed model can capture the observed different characteristics of MSW response from normal soil, such as nonlinear shear strength, pressure dependent stress dilatancy, and the reduced value of pore water pressure. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Relationship between Occupational Stress and Gastric Disease in Male Workers

    OpenAIRE

    Lihm, Ho-Seob; Park, Sang-Hyun; Gong, Eun-Hee; Choi, Jong-Soon; Kim, Jung-Won

    2012-01-01

    Background Physical and mental health of workers is threatened due to various events and chronic occupational stress. This study was conducted to investigate the relationship between occupational stress and gastric disease in male workers of the shipbuilding industry. Methods Occupational stress measured among a total of 498 workers of a shipbuilding firm who visited the hospital for health examination using the Korean Occupational Stress Scale (KOSS)-short form, and the relationship between ...

  4. Deformation and Fabric in Compacted Clay Soils

    Science.gov (United States)

    Wensrich, C. M.; Pineda, J.; Luzin, V.; Suwal, L.; Kisi, E. H.; Allameh-Haery, H.

    2018-05-01

    Hydromechanical anisotropy of clay soils in response to deformation or deposition history is related to the micromechanics of platelike clay particles and their orientations. In this article, we examine the relationship between microstructure, deformation, and moisture content in kaolin clay using a technique based on neutron scattering. This technique allows for the direct characterization of microstructure within representative samples using traditional measures such as orientation density and soil fabric tensor. From this information, evidence for a simple relationship between components of the deviatoric strain tensor and the deviatoric fabric tensor emerge. This relationship may provide a physical basis for future anisotropic constitutive models based on the micromechanics of these materials.

  5. Oxidative stress parameters in localized scleroderma patients.

    Science.gov (United States)

    Kilinc, F; Sener, S; Akbaş, A; Metin, A; Kirbaş, S; Neselioglu, S; Erel, O

    2016-11-01

    Localized scleroderma (LS) (morphea) is a chronic, inflammatory skin disease with unknown cause that progresses with sclerosis in the skin and/or subcutaneous tissues. Its pathogenesis is not completely understood. Oxidative stress is suggested to have a role in the pathogenesis of localized scleroderma. We have aimed to determine the relationship of morphea lesions with oxidative stress. The total oxidant capacity (TOC), total antioxidant capacity (TAC), paroxonase (PON) and arylesterase (ARES) activity parameters of PON 1 enzyme levels in the serum were investigated in 13 LS patients (generalized and plaque type) and 13 healthy controls. TOC values of the patient group were found higher than the TOC values of the control group (p < 0.01). ARES values of the patient group was found to be higher than the control group (p < 0.0001). OSI was significantly higher in the patient group when compared to the control (p < 0.005). Oxidative stress seems to be effective in the pathogenesis. ARES levels have increased in morphea patients regarding to the oxidative stress and its reduction. Further controlled studies are required in wider series.

  6. Atlas of stress-strain curves

    CERN Document Server

    2002-01-01

    The Atlas of Stress-Strain Curves, Second Edition is substantially bigger in page dimensions, number of pages, and total number of curves than the previous edition. It contains over 1,400 curves, almost three times as many as in the 1987 edition. The curves are normalized in appearance to aid making comparisons among materials. All diagrams include metric (SI) units, and many also include U.S. customary units. All curves are captioned in a consistent format with valuable information including (as available) standard designation, the primary source of the curve, mechanical properties (including hardening exponent and strength coefficient), condition of sample, strain rate, test temperature, and alloy composition. Curve types include monotonic and cyclic stress-strain, isochronous stress-strain, and tangent modulus. Curves are logically arranged and indexed for fast retrieval of information. The book also includes an introduction that provides background information on methods of stress-strain determination, on...

  7. Total Water Management: The New Paradigm for Urban Water Resources Planning

    Science.gov (United States)

    There is a growing need for urban water managers to take a more holistic view of their water resource systems as population growth, urbanization, and current resource management practices put different stresses on local water resources and urban infrastructure. Total Water Manag...

  8. Novel biochemical markers of psychosocial stress in women.

    Directory of Open Access Journals (Sweden)

    Marie Asberg

    Full Text Available BACKGROUND: Prolonged psychosocial stress is a condition assessed through self-reports. Here we aimed to identify biochemical markers for screening and early intervention in women. METHODS: Plasma concentrations of interleukin (IL 1-alpha, IL1-beta, IL-2, IL-4, IL-6, IL-8, IL-10, interferon-gamma (INF-gamma, tumor necrosis factor-alpha (TNF-alpha, monocyte chemotactic protein-1 (MCP-1, epidermal growth factor (EGF, vascular endothelial growth factor (VEGF, thyroid stimulating hormone (TSH, total tri-iodothyronine (TT3, total thyroxine (TT4, prolactin, and testosterone were measured in: 195 women on long-term sick-leave for a stress-related affective disorder, 45 women at risk for professional burnout, and 84 healthy women. RESULTS: We found significantly increased levels of MCP-1, VEGF and EGF in women exposed to prolonged psychosocial stress. Statistical analysis indicates that they independently associate with a significant risk for being classified as ill. CONCLUSIONS: MCP-1, EGF, and VEGF are potential markers for screening and early intervention in women under prolonged psychosocial stress.

  9. Left ventricular performance during psychological stress

    International Nuclear Information System (INIS)

    Young, D.Z.; Massachusetts General Hospital, Boston; Dimsdale, J.E.; Moore, R.H.; Barlai-Kovach, M.; Newell, J.B.; McKusick, K.A.; Boucher, C.A.; Fifer, M.A.; Strauss, H.W.

    1989-01-01

    Left ventricular ejection fraction, systolic blood pressure and plasma norepinephrine were measured in six normotensive and six mildly hypertensive subjects during rest and psychological stress. Compared with rest, 8 of the 12 subjects developed significant changes in ejection fraction (increase in 6, decrease in 2); 10 of 12 subjects developed significant elevations of plasma norepinephrine; and all developed significant increases in systolic blood pressure. When the stress effects were examined for the total group, as opposed to within subjects, there were significant increases in plasma norepinephrine and systolic blood pressure but, interestingly, mean ejection fraction and stroke volume remained unchanged, implying stress led to increased left ventricular contractility. (orig.)

  10. Long-term stability of oxidative stress biomarkers in human serum.

    NARCIS (Netherlands)

    Jansen, Eugène H J M; Beekhof, Piet K; Viezeliene, Dale; Muzakova, Vladimira; Skalicky, Jiri

    2017-01-01

    The storage time and storage temperature might affect stability of oxidative stress biomarkers, therefore, they have to be analyzed after long-term storage of serum samples. The stability of three biomarkers reflecting oxidative stress: reactive oxygen metabolites (ROM) for hydroperoxides, total

  11. [Nursery Teacher's Stress Scale (NTSS): reliability and validity].

    Science.gov (United States)

    Akada, Taro

    2010-06-01

    This study describes the development and evaluation of the Nursery Teacher's Stress Scale (NTSS), which explores the relation between daily hassles at work and work-related stress. In Analysis 1, 29 items were chosen to construct the NTSS. Six factors were identified: I. Stress relating to child care; II. Stress from human relations at work; III. Stress from staff-parent relations; IV. Stress from lack of time; V. Stress relating to compensation; and VI. Stress from the difference between individual beliefs and school policy. All these factors had high degrees of internal consistency. In Analysis 2, the concurrent validity of the NTSS was examined. The results showed that the NTSS total scores were significantly correlated with the Job Stress Scale-Revised Version (job stressor scale, r = .68), the Pre-school Teacher-efficacy Scale (r = -.21), and the WHO-five Well-Being Index Japanese Version (r = -.40). Work stresses are affected by several daily hassles at work. The NTSS has acceptable reliability and validity, and can be used to improve nursery teacher's mental health.

  12. [Effects on Stress, Problem Solving Ability and Quality of Life of as a Stress Management Program for Hospitalized Schizophrenic Patients: Based on the Stress, Appraisal-Coping Model of Lazarus & Folkman].

    Science.gov (United States)

    Park, Sun Ah; Sung, Kyung Mi

    2016-08-01

    The study was done to evaluate the effects a Stress Management Program (SMP) on stress, problem solving skills, and quality of life for hospitalized patients with Schizophrenia. A mixed method design was used: a combination of a repeated-measure design with a non-equivalent control group and qualitative data collection. The participants were 40 patients with schizophrenia admitted in three psychiatric hospitals. The experimental group (n=20) received the SMP twice a week for a total of 8 weeks. Study results revealed that the SMP was effective for stress (F=321.02, pproblem solving ability (F=246.28, peffective strategy to reduce patients' hospitalization stress, and improve problem solving skills and quality of life. Therefore, it is recommended that mental health nurses use this stress management program in clinical practice to assist adaptation to hospitalization for persons with schizophrenia.

  13. Does student debt affect dental students' and dentists' stress levels?

    Science.gov (United States)

    Boyles, J D; Ahmed, B

    2017-10-27

    Introduction Many studies have shown financial worries and debt to induce stress in individuals, this combined with the existing stress of being a dentist raises the question of how student debt affects students' and dentists' stress levels.Objectives Determine whether student debt has had any noticeable effect on student stress levels; investigate whether student debt has any effect on dentists' career choice; investigate whether the increase in tuition fees has influenced the number of applicants to study dentistry at the University of Birmingham.Method Anonymous questionnaires were completed by 70 4th year and 38 5th year BDS and 22 Dental Core Trainees (DCTs). Participants circled the response which best fitted their situation regarding statements on their level of stress and future career path. Ethical approval granted. Application figures to study dentistry obtained from head of admissions.Results Forty-two percent of males and 63% of females strongly agreed with the statement that having no debt would reduce their stress levels. Of those with debt >£40,000, 11% strongly agreed and 42% agreed that their total amount of student debt causes them stress. Whereas, those whose debt is stress. Seventy-seven percent of participants who had parental or family financial support reported this reduced their stress levels. Student debt was found to deter females from undertaking further study more than it deters males (P stressed about their total student loan(s) (P stress (P stress; students reporting a higher level of debt also report more stress and concern about paying off their student debt. Having no student debt would reduce stress levels, although to what extent is undetermined. Applications to study dentistry have fallen since the increase in tuition fees.

  14. Influence of gender and stress on the volatile sulfur compounds and stress biomarkers production.

    Science.gov (United States)

    Lima, P O; Calil, C M; Marcondes, F K

    2013-05-01

    Stress and menstrual cycle have been described as factors influencing bad breath, as they can alter oral homeostasis and contribute to the production of volatile sulfur compounds (VSC). Considering that the experimenter's and volunteer's gender may influence the volunteer's responses to stress, the aim of this work was to evaluate the influence of stress and gender on the production of VSC and salivary biomarkers. The experimental acute stress was induced by the Video-Recorded Stroop Color-Word Test (VRSCWT). The VSC, salivary proteins, and cardiovascular parameters were measured before and after VRSCWT. The VRSCWT induced significant increase in total VSC, hydrogen sulfide, and blood pressure values in men and women. Women presented higher values of both these compounds than men. The increase in systolic blood pressure was more pronounced when subjects were evaluated by an experimenter of the opposite gender. When women were evaluated by a member of the opposite gender, they showed significant increases in salivary alpha-amylase and cortisol compared with baseline values. Thus, the results showed that VRSCWT induced acute stress, which increased VSC production, and these effects were shown to be influenced by the gender. © 2012 John Wiley & Sons A/S.

  15. Relationship between the onset of depression and stress response measured by the Brief Job Stress Questionnaire among Japanese employees: a cohort study.

    Directory of Open Access Journals (Sweden)

    Keiko Wada

    Full Text Available BACKGROUND: The proportion of Japanese workers experiencing intense worry or stress during working life is in excess of 60%, and the incidence of psychiatric disorders and suicide due to psychological burden from work duties is increasing. To confirm whether the stress response measured by the Brief Job Stress Questionnaire (BJSQ can identify risk for depression, a cohort study was conducted to evaluate whether the stress response measured by BJSQ was associated with the onset of depression. METHODS: A total of 1,810 participants aged 20-70 years in 2005 completed the stress response of the BJSQ and were followed-up until August, 2007 by examining sick pay records. Depression was defined by a description in sick pay records that included "depression" or "depressive symptoms" as a reason for sick leave according to a physician's medical certificate. The participants were divided into quartiles (Ql, Q2, Q3, and Q4 according to the total stress response score of BJSQ at baseline. Furthermore, the participants were divided into a higher score category (Q4 and a lower score category (Q1-Q3. Risk ratios of the stress response of the BJSQ for onset of depression were calculated using a multivariable Cox proportional hazard model. RESULTS: Among 1,810 participants, 14 developed depression during a mean of 1.8 years of follow-up. The risk ratio was 2.96 (95% confidence interval [CI], 1.04-8.42, p for trend = 0.002 when the higher stress response score category of BJSQ was compared with the low stress response score category for sick leave due to depression. After adjusting for gender, age, marital status, and having children, the risk ratios were similar to no adjustment. CONCLUSIONS: These findings suggest that the stress response measured by the BJSQ can demonstrate risk for the onset of depression.

  16. A short-term supranutritional vitamin E supplementation alleviated respiratory alkalosis but did not reduce oxidative stress in heat stressed pigs.

    Science.gov (United States)

    Liu, Fan; Celi, Pietro; Chauhan, Surinder Singh; Cottrell, Jeremy James; Leury, Brian Joseph; Dunshea, Frank Rowland

    2018-02-01

    Heat stress (HS) triggers oxidative stress and respiratory alkalosis in pigs. The objective of this experiment was to study whether a short-term supranutritional amount of dietary vitamin E (VE) can mitigate oxidative stress and respiratory alkalosis in heat-stressed pigs. A total of 24 pigs were given either a control diet (17 IU/kg VE) or a high VE (200 IU/kg VE; HiVE) diet for 14 d, then exposed to thermoneutral (TN; 20°C, 45% humidity) or HS (35°C, 35% to 45% humidity, 8 h daily) conditions for 7 d. Respiration rate and rectal temperature were measured three times daily during the thermal exposure. Blood gas variables and oxidative stress markers were studied in blood samples collected on d 7. Although HiVE diet did not affect the elevated rectal temperature or respiration rate observed during HS, it alleviated (all prespiratory alkalosis but did not reduce oxidative stress in heat-stressed pigs.

  17. Web-Based and Mobile Stress Management Intervention for Employees

    DEFF Research Database (Denmark)

    Heber, E.; Lehr, D.; Ebert, D. D.

    2016-01-01

    Background: Work-related stress is highly prevalent among employees and is associated with adverse mental health consequences. Web-based interventions offer the opportunity to deliver effective solutions on a large scale; however, the evidence is limited and the results conflicting. Objective......: This randomized controlled trial evaluated the efficacy of guided Web-and mobile-based stress management training for employees. Methods: A total of 264 employees with elevated symptoms of stress (Perceived Stress Scale-10, PSS-10 >= 22) were recruited from the general working population and randomly assigned...... to an Internet-based stress management intervention (iSMI) or waitlist control group. The intervention (GET. ON Stress) was based on Lazarus's transactional model of stress, consisted of seven sessions, and applied both well-established problem solving and more recently developed emotion regulation strategies...

  18. Drought Stress Responses of Sunflower Germplasm Developed after Wide Hybridization

    Directory of Open Access Journals (Sweden)

    Roumiana Dimova Vassilevska-Ivanova

    2016-10-01

    Full Text Available Response of sunflower germplasms viz. cultivated sunflower H. annuus and two breeding lines H. annuus x T. rotundifolia and H. annuus x V. encelioides developed after wide hybridization were used for identification of drought tolerant sunflower genotypes at the seedling growth stage. Three water stress levels of zero (control, -0.4, and -0.8 MPa were developed using polyethyleneglycol-6000 (PEG-6000. Physiological and biochemical stress determining parameters such as root and shoots length, fresh weight, antioxidant enzyme activities (superoxide dismutase (SOD, catalase (CAT, guaiacol peroxidase (GPO, ascorbate peroxidase (APX and antioxidant metabolite content (total antioxidant capacity, total phenols and total flavonoids content were compared between seedlings of all three genotypes. Results revealed that sunflower genotypes have similar responses at two osmotic potentials for shoot and root length and fresh weight. The data also showed that drought stresss could induce oxidative stress, as indicated by the increase level of ascorbate peroxidase and guaiacol peroxidase at -04 MPa in H. annuus cv 1114. Although the activity of ascorbate peroxidase and guaiacol peroxidase was differentially influenced by drought, the changes of antioxidant enzyme activities such as catalase, superoxide dismutase, guaiacol peroxidase, and ascorbate peroxidase subjected to drought stress follow a similar pattern in both breeding lines, indicating that similar defense systems might be involved in the oxidative stress injury in sunflowers. Increase in content of phenols and flavonoids were detected for all three genotypes under stress, which showed that these were major antioxidant metabolites in scavenging cellular H2O2.

  19. Increased oxidative stress associated with the severity of the liver disease in various forms of hepatitis B virus infection.

    Science.gov (United States)

    Bolukbas, Cengiz; Bolukbas, Fusun Filiz; Horoz, Mehmet; Aslan, Mehmet; Celik, Hakim; Erel, Ozcan

    2005-10-31

    Oxidative stress can be defined as an increase in oxidants and/or a decrease in antioxidant capacity. There is limited information about the oxidative status in subjects with hepatitis B virus infection. We aimed to evaluate the oxidative status in patients with various clinical forms of chronic hepatitis B infection. Seventy-six patients with hepatitis B virus infection, in whom 33 with chronic hepatitis, 31 inactive carriers and 12 with cirrhosis, and 16 healthy subjects were enrolled. Total antioxidant response and total peroxide level measurement, and calculation of oxidative stress index were performed in all participants. Total antioxidant response was significantly lower in cirrhotics than inactive HbsAg carriers and controls (p = 0.008 and p = 0.008, respectively). Total peroxide level and oxidative stress index was significantly higher in cirrhotic (p Total antioxidant response was comparable in chronic hepatitis B subjects, inactive HbsAg carriers and controls (both, p > 0.05/6). Total peroxide level and oxidative stress index were also comparable in inactive HBsAg carriers and controls (both, p > 0.05/6). Serum alanine amino transferase level was positively correlated with total peroxide level and oxidative stress index only in chronic hepatitis B subjects (p = 0.002, r = 0.519 and p = 0.008, r = 0.453, respectively). Oxidative stress occurs secondarily to increased total lipid peroxidation and inadequate total antioxidant response and is related to severity of the disease and replication status of virus in hepatitis B infection.

  20. Oxidative stress and psychological functioning among medical students

    Directory of Open Access Journals (Sweden)

    Rani Srivastava

    2014-01-01

    Full Text Available Background: Oxidative stress has gained attention recently in behavioral medicine and has been reported to be associated with various psychological disturbances and their prognoses. Objectives: Study aims to evaluate the oxidative stress (malonylaldehyde (MDA levels and its relation with psychological factors (dimensions of personality, levels of anxiety, stress, and depression among medical/paramedical students of 1 st and 3 rd year. Materials and Methods: A total of 150 students; 75 from 1 st year (2010-2011 and75 from 3 rd year (2009-2010; of medical and paramedical background were assessed on level of MDA (oxidative stress and personality variables, that is, level of anxiety, stress, and depression. These psychological variables were correlated with the level of their oxidative stress. Results: Findings revealed that both groups are influenced by oxidative stress and their psychological variables are also compatible in order to confirm their vulnerabilities to stress. Conclusions: Stress in 3 rd year students was significantly higher and it was noted that it adversely affects the psychological parameters. Hence, special attention on mental health aspect in these students may be given.

  1. Oxidative stress and plasma lipoproteins in cancer patients

    Energy Technology Data Exchange (ETDEWEB)

    Maia, Fernanda Maria Machado; Santos, Emanuelly Barbosa; Reis, Germana Elias [Universidade Estadual do Ceará, Fortaleza, CE (Brazil)

    2014-07-01

    To evaluate the relation between oxidative stress and lipid profile in patients with different types of cancer. This was an observational cross-sectional. A total of 58 subjects were evaluated, 33 males, divided into two groups of 29 patients each: Group 1, patients with cancer of the digestive tract and accessory organs; Group 2 patients with other types of cancers, all admitted to a public hospital. The plasma levels (lipoproteins and total cholesterol, HDL, and triglycerides, for example) were analyzed by enzymatic kits, and oxidative stress based on thiobarbituric acid-reactive substances, by assessing the formation of malondialdehyde. In general the levels of malondialdehyde of patients were high (5.00μM) as compared to 3.31μM for healthy individuals. The median values of lipids exhibited normal triacylglycerol (138.78±89.88mg/dL), desirable total cholesterol values (163.04±172.38mg/dL), borderline high LDL (151.30±178.25mg/dL) and low HDL (31.70±22.74mg/dL). Median HDL levels in Group 1 were lower (31.32mg/dL) than the cancer patients in Group 2 (43.67mg/dL) (p=0.038). Group 1 also showed higher levels of oxidative stress (p=0.027). The lipid profile of patients with cancer was not favorable, which seems to have contributed to higher lipid peroxidation rate, generating a significant oxidative stress.

  2. Light energy dissipation under water stress conditions

    International Nuclear Information System (INIS)

    Stuhlfauth, T.; Scheuermann, R.; Fock, H.P.

    1990-01-01

    Using 14 CO 2 gas exchange and metabolite analyses, stomatal as well as total internal CO 2 uptake and evolution were estimated. Pulse modulated fluorescence was measured during induction and steady state of photosynthesis. Leaf water potential of Digitalis lanata EHRH. plants decreased to -2.5 megapascals after withholding irrigation. By osmotic adjustment, leaves remained turgid and fully exposed to irradiance even at severe water stress. Due to the stress-induced reduction of stomatal conductance, the stomatal CO 2 exchange was drastically reduced, whereas the total CO 2 uptake and evolution were less affected. Stomatal closure induced an increase in the reassimilation of internally evolved CO 2 . This CO 2 -recycling consumes a significant amount of light energy in the form of ATP and reducing equivalents. As a consequence, the metabolic demand for light energy is only reduced by about 40%, whereas net photosynthesis is diminished by about 70% under severe stress conditions. By CO 2 recycling, carbon flux, enzymatic substrate turnover and consumption of light energy were maintained at high levels, which enabled the plant to recover rapidly after rewatering. In stressed D. lanata plants a variable fluorescence quenching mechanism, termed coefficient of actinic light quenching, was observed. Besides water conservation, light energy dissipation is essential and involves regulated metabolic variations

  3. The total triterpenoid saponins of Xanthoceras sorbifolia improve learning and memory impairments through against oxidative stress and synaptic damage.

    Science.gov (United States)

    Ji, Xue-Fei; Chi, Tian-Yan; Liu, Peng; Li, Lu-Yi; Xu, Ji-Kai; Xu, Qian; Zou, Li-Bo; Meng, Da-Li

    2017-02-15

    X. sorbifolia is a widely cultivated ecologicalcrop in the north of China which is used to produce biodiesel fuel. It also possesses special medicinal value and has attracted keen interests of researchers to explore its bioactivity. To extract the total triterpenoid saponins from the husk of X. sorbifolia (TSX) and investigate its effects on Alzheimer's disease (AD). TSX was prepared via modern extraction techniques. Its effects on two AD animal models, as well as the preliminary mechanism were investigated comprehensively. The behavioral experiments including Y maze test, Morris water maze test and passive avoidance test were performed to observe the learning and memory abilities of the animals. ELISA assays, transmission electron microscope observation and Western blotting were employed in mechanism study. TSX, the main composition of X. sorbifolia, accounted for 88.77% in the plant material. It could significantly increase the spontaneous alternation in Y maze test (F (6, 65)=3.209, Plearning and memory. The preliminary mechanism might associate with its protection effects against oxidative stress damage, cholinergic system deficiency and synaptic damage. TSX are perfectly suitable for AD patients as medicine or functional food, which would be a new candidate to treat AD. Copyright © 2016 Elsevier GmbH. All rights reserved.

  4. Grafting improves cucumber water stress tolerance in Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Abdulaziz R. Al-Harbi

    2018-02-01

    Full Text Available Water scarcity is a major limiting factor for crop productivity in arid and semi-arid areas. Grafting elite commercial cultivars onto selected vigorous rootstocks is considered as a useful strategy to alleviate the impact of environmental stresses. This study aims to investigate the feasibility of using grafting to improve fruit yield and quality of cucumber under water stress conditions. Alosama F1 cucumber cultivar (Cucumis sativus L. was grafted onto Affyne (Cucumis sativus L. and Shintoza A90 (Cucurbitamaxima × C. moschata rootstocks. Non-grafted plants were used as control. All genotypes were grown under three surface drip irrigation regimes: 50%, 75% and 100% of the crop evapotranspiration (ETc, which represent high-water stress, moderate-water stress and non-water stress conditions, respectively. Yield and fruit quality traits were analyzed and assessed. In comparison to the non-grafted plants, the best grafting treatment under water stress was Alosama F1 grafted onto Shintoza A90 rootstock. It had an overall improved yield and fruit quality under water stress owing to an increase in the total fruit yield by 27%, from 4.815 kg plant−1 in non-grafted treatment to 6.149 kg plant−1 in grafted treatment under moderate -water stress, total soluble solid contents (13%, titratable acidity (39% and vitamin C (33%. The soil water contents were low in soil surface and increase gradually with soil depth, while salt distribution showed an adverse trend. The positive effects of grafting on plant growth, productivity, and water use efficiency support this strategy as an useful tool for improving water stress tolerance in greenhouse grown cucumber in Saudi Arabia.

  5. Grafting improves cucumber water stress tolerance in Saudi Arabia.

    Science.gov (United States)

    Al-Harbi, Abdulaziz R; Al-Omran, Abdulrasoul M; Alharbi, Khadiga

    2018-02-01

    Water scarcity is a major limiting factor for crop productivity in arid and semi-arid areas. Grafting elite commercial cultivars onto selected vigorous rootstocks is considered as a useful strategy to alleviate the impact of environmental stresses. This study aims to investigate the feasibility of using grafting to improve fruit yield and quality of cucumber under water stress conditions. Alosama F 1 cucumber cultivar ( Cucumis sativus L.) was grafted onto Affyne ( Cucumis sativus L.) and Shintoza A90 ( Cucurbitamaxima × C. moschata ) rootstocks. Non-grafted plants were used as control. All genotypes were grown under three surface drip irrigation regimes: 50%, 75% and 100% of the crop evapotranspiration (ETc), which represent high-water stress, moderate-water stress and non-water stress conditions, respectively. Yield and fruit quality traits were analyzed and assessed. In comparison to the non-grafted plants, the best grafting treatment under water stress was Alosama F 1 grafted onto Shintoza A90 rootstock. It had an overall improved yield and fruit quality under water stress owing to an increase in the total fruit yield by 27%, from 4.815 kg plant -1 in non-grafted treatment to 6.149 kg plant -1 in grafted treatment under moderate -water stress, total soluble solid contents (13%), titratable acidity (39%) and vitamin C (33%). The soil water contents were low in soil surface and increase gradually with soil depth, while salt distribution showed an adverse trend. The positive effects of grafting on plant growth, productivity, and water use efficiency support this strategy as an useful tool for improving water stress tolerance in greenhouse grown cucumber in Saudi Arabia.

  6. [An investigation of occupational stress, social support, and happiness of junior civil servants].

    Science.gov (United States)

    Wang, Lingfeng

    2015-10-01

    To investigate the current status of occupational stress, social support, and happiness in junior civil servants in northern Zhejiang Province, China, and to investigate the relationship between occupational stress, social support and happiness. A total of 360 junior civil servants from below-county-level administrative organizations in Huzhou, Jiaxing, and Hangzhou were surveyed using the job stress questionnaire and social support rating scale for civil servants. The total average score of occupational stress in junior civil servants was 2.52 ± 0.48, indicating a moderate level of occupational stress; career prospects topped the rank list of sources of occupational stress with a score of 2.90 ± 0.60; different generations showed significant differences in the sources and total average scores of occupational stress, with the scores of the 1980s, 1990s, 1970s, 1950s, and 1960s groups decreasing in the same order (Phappiness among the junior civil servants were relatively low, with scores of 38.43 ± 8.38 and 76.88 ± 12.77, respectively; different generations also showed significant differences, with the scores of 1980s, 1990s, 1970s, 1950s, and 1960s groups increasing in the same order (Phappiness than males (Phappiness of junior civil servants (r=0.405~0.571, Phappiness of junior civil servants.

  7. Effectiveness of patient empowerment over stress related to knee arthroplasty surgery.

    Science.gov (United States)

    Garzón-Rey, Jorge Mario; Arza-Valdés, Adriana; Nuevo-Gayoso, Montserrat; Aguiló, Jordi

    This study aims to show evidence of the Empowerment Session's effectiveness through measurements of surgery related emotional stress before and after this session. The study was performed on 41 patients with knee arthroplasty surgery prescription by measuring the evolution of their emotional stress generated by surgery expectative, during the empowerment session. Two sets of measurements per patient were performed, before and after the empowerment session. Each set consisted of recording an electrocardiogram for 10min while the patients were seated and then applying two standard psychometric tests: State-Trait Anxiety Inventory test and Visual Analog Stress test. Differences in emotional stress were analyzed using psychometric tests and heart rate variability (HRV) analysis as stress biomarkers. Psychometric stress measurement shows a 17.8% reduction in stress according to the total stress scale value, and a 41.9% reduction in stress between test results before and after the session. Mean heart rate values increased by 7.4% with respect to the initial values, very low frequency power and total power also change in value suggesting more sympathetic and less parasympathetic activity. Both psychological and physiological measurements suggest the effectiveness of the empowerment session due to a significant increase in the wellness state of patients. Additionally, the correlation between psychometric tests and HRV indices demonstrates that both emotional stress indicators could be used as feedback on the empowerment sessions or as a reference to enhance surgical outcomes. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  8. Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioning.

    Science.gov (United States)

    Giachero, Marcelo; Calfa, Gaston D; Molina, Victor A

    2013-10-15

    The present research investigated the resulting contextual fear memory and structural plasticity changes in the dorsal hippocampus (DH) following stress and fear conditioning. This combination enhanced fear retention and increased the number of total and mature dendritic spines in DH. Intra-basolateral amygdala (BLA) infusion of midazolam prior to stress prevented both the enhancement of fear retention and an increase in the density of total and mature dendritic spines in DH. These findings emphasize the role of the stress-induced attenuation of GABAergic neurotransmission in BLA in the promoting influence of stress on fear memory and on synaptic remodeling in DH. In conclusion, the structural remodeling in DH accompanied the facilitated fear memory following a combination of fear conditioning and stressful stimulation.

  9. Depression, anxiety and stress in dental students

    OpenAIRE

    Basudan, Sumaya; Binanzan, Najla; Alhassan, Aseel

    2017-01-01

    Objectives To measure the occurrence and levels of depression, anxiety and stress in undergraduate dental students using the Depression, Anxiety and Stress Scale (DASS-21). Methods This cross-sectional study was conducted in November and December of 2014. A total of 289 dental students were invited to participate, and 277 responded, resulting in a response rate of 96%. The final sample included 247 participants. Eligible participants were surveyed via a self-reported questionnaire that includ...

  10. Electroconvulsive stimulations prevent stress-induced morphological changes in the hippocampus

    DEFF Research Database (Denmark)

    Hageman, I; Nielsen, M; Wörtwein, Gitta

    2008-01-01

    whether repeated electroconvulsive stimulations (ECSs) could influence such changes in stressed rats. Furthermore, we investigated whether ECSs per se could influence neuronal branching and total length of the CA3 hippocampal neuronal dendritic tree in normal rats. Rats were stressed using the 21-day 6 h...

  11. Residual stress effects in LMFBR fracture assessment procedures

    International Nuclear Information System (INIS)

    Hooton, D.G.

    1984-01-01

    Two post-yield fracture mechanics methods, which have been developed into fully detailed failure assessment procedures for ferritic structures, have been reviewed from the point of view of the manner in which as-welded residual stress effects are incorporated, and comparisons then made with finite element and theoretical models of centre-cracked plates containing residual/thermal stresses in the form of crack-driving force curves. Applying the procedures to austenitic structures, comparisons are made in terms of failure assessment curves and it is recommended that the preferred method for the prediction of critical crack sizes in LMFBR austenitic structures containing as-welded residual stresses is the CEGB-R6 procedure based on a flow stress defined at 3% strain in the parent plate. When the prediction of failure loads in such structures is required, it is suggested that the CEGB-R6 procedure be used with residual/thermal stresses factored to give a maximum total stress of flow stress magnitude

  12. Estado oxidante/antioxidante total em recém-nascidos ictéricos antes e depois da fototerapia Total oxidant/antioxidant status in jaundiced newborns before and after phototherapy

    Directory of Open Access Journals (Sweden)

    Ali Aycicek

    2007-08-01

    Full Text Available OBJETIVO: Avaliar o efeito da fototerapia no estado oxidante e antioxidante no soro de recém-nascidos a termo com hiperbilirrubinemia. MÉTODO: Trinta e quatro recém-nascidos a termo com idades entre 3 e 10 dias submetidos a fototerapia foram avaliados. O estado antioxidante do soro foi determinado pela capacidade antioxidante total e por componentes antioxidantes individuais: vitamina C, ácido úrico, albumina, concentração de tiol e bilirrubina total. O estado oxidante foi avaliado através do estado oxidante total, índice de estresse oxidativo e componentes oxidantes individuais: malondialdeído e níveis de hidroperóxido lipídico. RESULTADOS: As concentrações de vitamina C, ácido úrico, bilirrubina total e malondialdeído foram significativamente mais baixas, enquanto que o estado oxidante total, níveis de hidroperóxido lipídico e o índice de estresse oxidativo foram significativamente maiores após a fototerapia (p OBJECTIVE: To assess the effect of phototherapy on serum oxidant and antioxidant status in hyperbilirubinemic full-term newborns. METHOD: Thirty-four full-term infants from 3 to 10 days of age exposed to phototherapy were studied. The serum antioxidant status was assessed by measuring the total antioxidant capacity (TAC and individual antioxidant components: vitamin C, uric acid, albumin, thiol contents and total bilirubin. The oxidant status was assessed by determining the total oxidant status (TOS, oxidative stress index (OSI and individual oxidant components: malondialdehyde (MDA, and lipid hydroperoxide levels. RESULTS: Vitamin C, uric acid, total bilirubin and MDA concentration were significantly lower, whereas serum TOS, lipid hydroperoxide and OSI levels were significantly higher after phototherapy (p < 0.05. There were significant positive correlations between serum total bilirubin and MDA (r = 0.434, p = 0.001. CONCLUSIONS: Although the MDA level was reduced after phototherapy, phototherapy has a negative

  13. Plasma Total Cysteine and Cardiovascular Risk Burden: Action and Interaction

    Directory of Open Access Journals (Sweden)

    Benedetta De Chiara

    2012-01-01

    Full Text Available We hypothesized that redox analysis could provide sensitive markers of the oxidative pathway associated to the presence of an increasing number of cardiovascular risk factors (RFs, independently of type. We classified 304 subjects without cardiovascular disease into 4 groups according to the total number of RFs (smoking, hypertension, hypercholesterolaemia, hyperhomocysteinaemia, diabetes, obesity, and their combination. Oxidative stress was evaluated by measuring plasma total and reduced homocysteine, cysteine (Cys, glutathione, cysteinylglycine, blood reduced glutathione, and malondialdehyde. Twenty-seven percent of subjects were in group 0 RF, 26% in 1 RF, 31% in 2 RF, and 16% in ≥3 RF. By multivariable ordinal regression analysis, plasma total Cys was associated to a higher number of RF (OR = 1.068; 95% CI = 1.027–1.110, =0.002. Total RF burden is associated with increased total Cys levels. These findings support a prooxidant effect of Cys in conjunction with RF burden, and shed light on the pathophysiologic role of redox state unbalance in preclinical atherosclerosis.

  14. Adaptive bone remodeling and biomechanical design considerations : for noncemented total hip arthroplasty

    NARCIS (Netherlands)

    Huiskes, H.W.J.; Weinans, H.; Dalstra, M.

    1989-01-01

    Clinical problems with noncemented total hip arthroplasty (THA) stems, directly or indirectly related to load transfer, include mid-thigh pain due to relative (micro) motions or excessive endosteal interface stresses, subsidence and loosening due to inadequate primary stability and fit, and proximal

  15. Interactive effects of salinity stress and nicotinamide on physiological and biochemical parameters of Faba bean plant

    International Nuclear Information System (INIS)

    Abdelhamid, Magdi T; Sadak, Mervat Sh; Schmidhalter, Urs; El Saady, Abdel Kareem M.

    2013-01-01

    A possible survival strategy for plants under saline conditions is to use some compounds that could alleviate the salt stress effect. One of these compounds is nicotinamide (vitamin B3/niacin). The effect of exogenous application of nicotinamide with different concentrations (0,200 or 400 mg l-1) on faba bean (Vicia faba L.) plant grown at different NaCl levels (0,50 or 100 mM) was investigated in the wire house of the National Research Centre, Cairo, Egypt. Salinity stress significantly reduced the photosynthetic pigments, polysaccharides, total carbohydrates, total-N contents of shoot, plant height, leaves number, fresh and dry weights of shoot, seed yield, total carbohydrates and total crude protein of the yielded seeds compared with those of the control plants. In contrast, salinity induced marked increases in sucrose, total soluble sugars, total free amino acids, proline, lipid peroxidation product (MDA) and some oxidative enzymes (polyphenol-oxidase and peroxidase). Also, salinity stress increased Na+ contents with the decreases of other macro and micro elements contents (P, K+, Mg_2+, Ca_2+, Fe_2+, Mn_2+, Zn_2+ and Cu_2+) of shoots and the yielded seeds of faba bean. Foliar spraying of nicotinamide alleviated the adverse effects of salinity stress through increased the photosynthetic pigments, polysaccharides, total carbohydrates, total N concentration of shoot, plant height, leaves number, fresh and dry weights of shoot, and seed yield as well as, sucrose, total soluble sugars, total free amino acids and proline, compared with those of the corresponding salinity levels, while decreased lipid peroxidation product as malondialdehyde (MDA) and the oxidative enzymes (polyphenol oxidase and peroxidase enzymes). Nicotinamide inhibited the uptake of Na+ and accelerated the accumulation of P, K+, Mg_2+, Ca_2+, Fe_2+, Mn_2+, Zn_2+ and Cu_2+ concentrations in the shoots of salt stressed plants and enhanced total carbohydrate and total crude protein percentage and

  16. Investigation on stresses of superconductors under pulsed magnetic fields based on multiphysics model

    International Nuclear Information System (INIS)

    Yang, Xiaobin; Li, Xiuhong; He, Yafeng; Wang, Xiaojun; Xu, Bo

    2017-01-01

    Highlights: • The differential equation including temperature and magnetic field was derived for a long cylindrical superconductor. • Thermal stress and electromagnetic stress were studied at the same time under pulse field magnetizing. • The distributions of the magnetic field, the temperature and stresses are studied and compared for two pulse fields of the different duration. • The Role thermal stress and electromagnetic stress play in the process of pulse field magnetizing is discussed. - Abstract: A multiphysics model for the numerical computation of stresses, trapped field and temperature distribution of a infinite long superconducting cylinder is proposed, based on which the stresses, including the thermal stresses and mechanical stresses due to Lorentz force, and trapped fields in the superconductor subjected to pulsed magnetic fields are analyzed. By comparing the results under pulsed magnetic fields with different pulse durations, it is found that the both the mechanical stress due to the electromagnetic force and the thermal stress due to temperature gradient contribute to the total stress level in the superconductor. For pulsed magnetic field with short durations, the thermal stress is the dominant contribution to the total stress, because the heat generated by AC-loss builds up significant temperature gradient in such short durations. However, for a pulsed field with a long duration the gradient of temperature and flux, as well as the maximal tensile stress, are much smaller. And the results of this paper is meaningful for the design and manufacture of superconducting permanent magnets.

  17. Investigation on stresses of superconductors under pulsed magnetic fields based on multiphysics model

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Xiaobin, E-mail: yangxb@lzu.edu.cn; Li, Xiuhong; He, Yafeng; Wang, Xiaojun; Xu, Bo

    2017-04-15

    Highlights: • The differential equation including temperature and magnetic field was derived for a long cylindrical superconductor. • Thermal stress and electromagnetic stress were studied at the same time under pulse field magnetizing. • The distributions of the magnetic field, the temperature and stresses are studied and compared for two pulse fields of the different duration. • The Role thermal stress and electromagnetic stress play in the process of pulse field magnetizing is discussed. - Abstract: A multiphysics model for the numerical computation of stresses, trapped field and temperature distribution of a infinite long superconducting cylinder is proposed, based on which the stresses, including the thermal stresses and mechanical stresses due to Lorentz force, and trapped fields in the superconductor subjected to pulsed magnetic fields are analyzed. By comparing the results under pulsed magnetic fields with different pulse durations, it is found that the both the mechanical stress due to the electromagnetic force and the thermal stress due to temperature gradient contribute to the total stress level in the superconductor. For pulsed magnetic field with short durations, the thermal stress is the dominant contribution to the total stress, because the heat generated by AC-loss builds up significant temperature gradient in such short durations. However, for a pulsed field with a long duration the gradient of temperature and flux, as well as the maximal tensile stress, are much smaller. And the results of this paper is meaningful for the design and manufacture of superconducting permanent magnets.

  18. Proline accumulation in water-stressed barley leaves in relation to translocation and the nitrogen budget

    International Nuclear Information System (INIS)

    Tully, R.E.; Hanson, A.D.; Nelsen, C.E.

    1979-01-01

    Mobilization of N from leaves of barley (Hordeum vulgare L.) during water stress, and the role of proline as a mobilized species, were examined in plants at the three-leaf stage. The plants responded to water stress by withdrawing about 25% of the total reduced N from the leaf blades via phloem translocation. Most of this N loss was during the first 2 days while translocation of 14 C-photosynthate out of the stressed blade still remained active. Free proline accumulation in the blade was initially slow, and became more rapid during the 2nd day of stress. Although a major free amino acid, proline accounted for only about 5% of the total N(soluble + insoluble) retained in severely stressed blades. When the translocation pathway in water-stressed leaves was interrupted just below the blade by a heat girdle, a cold jacket, or by blade excision, N loss from the blade was prevented and proline began to accumulate rapidly on 1st day of stress. Little free proline accumulated in the blades until after the ability to translocate was lost. Proline was, however, probably not a major species of N translocated during stress, because proline N accumulation in heat-girdled stressed leaves was five times slower than the rate of total N export from intact blades

  19. Management of work-related stress by Finnish occupational physicians.

    Science.gov (United States)

    Kinnunen-Amoroso, M; Liira, J

    2013-07-01

    Occupational stress is a serious threat to the well-being of employees and organizations and may cause ill-health and loss of productivity. Determining the methods that occupational health (OH) services and employers use to manage work-related stress can help to detect both barriers and facilitating factors for effective stress management. To examine stress management methods used by OH physicians in Finland. Anonymous, self-administered e-mail questionnaire to Finnish OH physicians. A total of 222 OH physicians responded. Neither OH services nor their client organizations used standardized tools to assess or manage work-related stress. Work-related stress was assessed using patient interviews. Physicians reported that the main method used to manage occupational stress was supporting the individual employee. Half of the physicians attempted to involve workplaces in stress management by asking their patients to contact their supervisors regarding stress issues. In order to tackle work-related stress consistently and effectively employers and OH services should have agreed standardized protocols for managing stress in the workplace.

  20. Elevated atmospheric CO2 affected photosynthetic products in wheat seedlings and biological activity in rhizosphere soil under cadmium stress.

    Science.gov (United States)

    Jia, Xia; Liu, Tuo; Zhao, Yonghua; He, Yunhua; Yang, Mingyan

    2016-01-01

    The objective of this study was to investigate the effects of elevated CO2 (700 ± 23 μmol mol(-1)) on photosynthetic products in wheat seedlings and on organic compounds and biological activity in rhizosphere soil under cadmium (Cd) stress. Elevated CO2 was associated with decreased quantities of reducing sugars, starch, and soluble amino acids, and with increased quantities of soluble sugars, total sugars, and soluble proteins in wheat seedlings under Cd stress. The contents of total soluble sugars, total free amino acids, total soluble phenolic acids, and total organic acids in the rhizosphere soil under Cd stress were improved by elevated CO2. Compared to Cd stress alone, the activity of amylase, phenol oxidase, urease, L-asparaginase, β-glucosidase, neutral phosphatase, and fluorescein diacetate increased under elevated CO2 in combination with Cd stress; only cellulase activity decreased. Bacterial abundance in rhizosphere soil was stimulated by elevated CO2 at low Cd concentrations (1.31-5.31 mg Cd kg(-1) dry soil). Actinomycetes, total microbial abundance, and fungi decreased under the combined conditions at 5.31-10.31 mg Cd kg(-1) dry soil. In conclusion, increased production of soluble sugars, total sugars, and proteins in wheat seedlings under elevated CO2 + Cd stress led to greater quantities of organic compounds in the rhizosphere soil relative to seedlings grown under Cd stress only. Elevated CO2 concentrations could moderate the effects of heavy metal pollution on enzyme activity and microorganism abundance in rhizosphere soils, thus improving soil fertility and the microecological rhizosphere environment of wheat under Cd stress.

  1. Quercetin prevents chronic unpredictable stress induced behavioral dysfunction in mice by alleviating hippocampal oxidative and inflammatory stress.

    Science.gov (United States)

    Mehta, Vineet; Parashar, Arun; Udayabanu, Malairaman

    2017-03-15

    It is now evident that chronic stress is associated with anxiety, depression and cognitive dysfunction and very few studies have focused on identifying possible methods to prevent these stress-induced disorders. Previously, we identified abundance of quercetin in Urtica dioica extract, which efficiently attenuated stress related complications. Therefore, current study was designed to investigate the effect of quercetin on chronic unpredicted stress (CUS) induced behavioral dysfunction, oxidative stress and neuroinflammation in the mouse hippocampus. Animals were subjected to unpredicted stress for 21days, during which 30mg/kg quercetin was orally administered to them. Effect of CUS and quercetin treatment on animal behavior was assessed between day 22-26. Afterward, the hippocampus was processed to evaluate neuronal damage, oxidative and inflammatory stress. Results revealed that stressed animals were highly anxious (Elevated Plus Maze and Open Field), showed depressive-like behavior (sucrose preference task), performed poorly in short-term and long-term associative memory task (passive avoidance step-through task) and displayed reduced locomotion (open field). Quercetin alleviated behavioral dysfunction in chronically stressed animals. Compared to CUS, quercetin treatment significantly reduced anxiety, attenuated depression, improved cognitive dysfunction and normalized locomotor activity. Further, CUS elevated the levels of oxidative stress markers (TBARS, nitric oxide), lowered antioxidants (total thiol, catalase), enhanced expression of pro-inflammatory cytokines (IL-6, TNF-α, IL-1β and COX-2) in the hippocampus and damaged hippocampal neurons. Quercetin treatment significantly lowered oxidative and inflammatory stress and prevented neural damage. In conclusion, quercetin can efficiently prevent stress induced neurological complications by rescuing brain from oxidative and inflammatory stress. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Long range stress correlations in the inherent structures of liquids at rest

    Energy Technology Data Exchange (ETDEWEB)

    Chowdhury, Sadrul; Abraham, Sneha; Hudson, Toby; Harrowell, Peter [School of Chemistry, University of Sydney, Sydney, NSW 2006 (Australia)

    2016-03-28

    Simulation studies of the atomic shear stress in the local potential energy minima (inherent structures) are reported for binary liquid mixtures in 2D and 3D. These inherent structure stresses are fundamental to slow stress relaxation and high viscosity in supercooled liquids. We find that the atomic shear stress in the inherent structures (IS’s) of both liquids at rest exhibits slowly decaying anisotropic correlations. We show that the stress correlations contribute significantly to the variance of the total shear stress of the IS configurations and consider the origins of the anisotropy and spatial extent of the stress correlations.

  3. Increased oxidative stress associated with the severity of the liver disease in various forms of hepatitis B virus infection

    Directory of Open Access Journals (Sweden)

    Aslan Mehmet

    2005-10-01

    Full Text Available Abstract Background Oxidative stress can be defined as an increase in oxidants and/or a decrease in antioxidant capacity. There is limited information about the oxidative status in subjects with hepatitis B virus infection. We aimed to evaluate the oxidative status in patients with various clinical forms of chronic hepatitis B infection. Methods Seventy-six patients with hepatitis B virus infection, in whom 33 with chronic hepatitis, 31 inactive carriers and 12 with cirrhosis, and 16 healthy subjects were enrolled. Total antioxidant response and total peroxide level measurement, and calculation of oxidative stress index were performed in all participants. Results Total antioxidant response was significantly lower in cirrhotics than inactive HbsAg carriers and controls (p = 0.008 and p = 0.008, respectively. Total peroxide level and oxidative stress index was significantly higher in cirrhotic (p 0.05/6. Total peroxide level and oxidative stress index were also comparable in inactive HBsAg carriers and controls (both, p > 0.05/6. Serum alanine amino transferase level was positively correlated with total peroxide level and oxidative stress index only in chronic hepatitis B subjects (p = 0.002, r = 0.519 and p = 0.008, r = 0.453, respectively. Conclusion Oxidative stress occurs secondarily to increased total lipid peroxidation and inadequate total antioxidant response and is related to severity of the disease and replication status of virus in hepatitis B infection.

  4. Total ankle joint replacement.

    Science.gov (United States)

    2016-02-01

    Ankle arthritis results in a stiff and painful ankle and can be a major cause of disability. For people with end-stage ankle arthritis, arthrodesis (ankle fusion) is effective at reducing pain in the shorter term, but results in a fixed joint, and over time the loss of mobility places stress on other joints in the foot that may lead to arthritis, pain and dysfunction. Another option is to perform a total ankle joint replacement, with the aim of giving the patient a mobile and pain-free ankle. In this article we review the efficacy of this procedure, including how it compares to ankle arthrodesis, and consider the indications and complications. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  5. Interventions: Employees’ Perceptions of What Reduces Stress

    Directory of Open Access Journals (Sweden)

    Silvia Pignata

    2017-01-01

    Full Text Available Objective. To build upon research evaluating stress interventions, this qualitative study tests the framework of the extended Job Demands-Resources model to investigate employees’ perceptions of the stress-reduction measures implemented at 13 Australian universities. Methods. In a cross-sectional survey design, tenured and contract staff indicated whether their overall level of stress had changed during the previous three-four years, and, if so, they described the major causes. A total of 462 staff reported that their level of stress had decreased; the study examines commentary from 115 academic and 304 nonacademic staff who provided details of what they perceived to be effective in reducing stress. Results. Thematic analyses show that the key perceived causes were changes in job or work role, new heads of departments or supervisors, and the use of organizational strategies to reduce or manage stress. A higher percentage of academic staff reported reduced stress due to using protective coping strategies or their increased recognition and/or success, whereas a higher percentage of nonacademic staff reported reduced stress due to increases in staffing resources and/or systems. Conclusion. These results identify the importance of implementing multilevel strategies to enhance employees’ well-being. Nonacademic staff, in particular, specified a variety of organizational stress-reduction interventions.

  6. The effect of academic stress and attachment stress on stress-eaters and stress-undereaters.

    Science.gov (United States)

    Emond, Michael; Ten Eycke, Kayla; Kosmerly, Stacey; Robinson, Adele Lafrance; Stillar, Amanda; Van Blyderveen, Sherry

    2016-05-01

    It is well established that stress is related to changes in eating patterns. Some individuals are more likely to increase their overall food intake under conditions of stress, whereas others are more likely to consume less food when stressed. Attachment style has been linked to disordered eating and eating disorders; however, comparisons of eating behaviors under attachment versus other types of stress have yet to be explored. The present laboratory study examined the eating patterns in self-identified stress-undereaters and stress-eaters under various types of stress. More specifically, the study examined the effects of academic and attachment stress on calorie, carbohydrate and sugar consumption within these two groups. Under the guise of critiquing student films, university students viewed either one of two stress-inducing videos (academic stress or attachment stress, both designed to be emotionally arousing) or a control video (designed to be emotionally neutral), and their food intake was recorded. Results demonstrated that the video manipulations were effective in inducing stress. Differential patterns of eating were noted based on group and stress condition. Specifically, stress-undereaters ate fewer calories, carbohydrates and sugars than stress-eaters in the academic stress condition, but not in the attachment stress or control condition. Findings suggest that specific types of stressors may influence eating behaviors differently. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. [Effect of occupational stress on oxidation/antioxidant capacity in nurses].

    Science.gov (United States)

    Cao, Lili; Tian, Honger; Zhang, Qingdong; Zhu, Xinyun; Zhan, Yongguo; Su, Jingguo; Xu, Tian; Zhu, Huabin; Liu, Ling

    2014-02-01

    To investigate the effect of occupational stress on the oxidation/antioxidant capacity in nurses. A total of 131 nurses were included as study subjects. The occupational health information collection system (based on the Internet of things) was used for measurement of occupational stress. Levels of hydroxyl free radicals and antioxidant enzymes were determined. The serum level of superoxide dismutase (SOD) was the highest in nurses under the age of 30 and the lowest in those over 45 (P occupational stress factors for SOD. Job hazards were negative occupational stress factors for POD. Psychological satisfaction was negative occupational stress reaction for hydroxyl free radicals. Calmness was positive occupational stress reaction for SOD, and daily stress was a negative one. The positive occupational stress reactions for GSH-Px were psychological satisfaction and job satisfaction, and daily stress was negative reaction. Nurses with higher occupational stress have stronger oxidation and weaker antioxidant capacity, which intensifies oxidant-antioxidant imbalance and leads to oxidative stress damage.

  8. A Comparison between Deep and Shallow Stress Fields in Korea Using Earthquake Focal Mechanism Inversions and Hydraulic Fracturing Stress Measurements

    Science.gov (United States)

    Lee, Rayeon; Chang, Chandong; Hong, Tae-kyung; Lee, Junhyung; Bae, Seong-Ho; Park, Eui-Seob; Park, Chan

    2016-04-01

    We are characterizing stress fields in Korea using two types of stress data: earthquake focal mechanism inversions (FMF) and hydraulic fracturing stress measurements (HF). The earthquake focal mechanism inversion data represent stress conditions at 2-20 km depths, whereas the hydraulic fracturing stress measurements, mostly conducted for geotechnical purposes, have been carried out at depths shallower than 1 km. We classified individual stress data based on the World Stress Map quality ranking scheme. A total of 20 FMF data were classified into A-B quality, possibly representing tectonic stress fields. A total of 83 HF data out of compiled 226 data were classified into B-C quality, which we use for shallow stress field characterization. The tectonic stress, revealed from the FMF data, is characterized by a remarkable consistency in its maximum stress (σ1) directions in and around Korea (N79±2° E), indicating a quite uniform deep stress field throughout. On the other hand, the shallow stress field, represented by HF data, exhibits local variations in σ1 directions, possibly due to effects of topography and geologic structures such as faults. Nonetheless, there is a general similarity in σ1 directions between deep and shallow stress fields. To investigate the shallow stress field statistically, we follow 'the mean orientation and wavelength analysis' suggested by Reiter et al. (2014). After the stress pattern analysis, the resulting stress points distribute sporadically over the country, not covering the entire region evenly. In the western part of Korea, the shallow σ1directions are generally uniform with their search radius reaching 100 km, where the average stress direction agrees well with those of the deep tectonic stress. We note two noticeable differences between shallow and deep stresses in the eastern part of Korea. First, the shallow σ1 orientations are markedly non-uniform in the southeastern part of Korea with their search radius less than 25 km

  9. On formal structure of constitutive equations for materials exhibiting shape memory effects

    International Nuclear Information System (INIS)

    Dobovsek, I.

    2000-01-01

    A derivation of constitutive equations in a general three-dimensional setting is described, based on an additive decomposition of the rate of deformation tensor. The rate of deformation tensor is assumed to consist of an elastic part, a thermoelastic part, a plastic part, a part due to shape memory transformation, and a part due to phase transformation. The thermoelastic part due to thermoelastic coupling accounts for the influence of temperature near phase transformation, while the plastic part is taken in the form of classical J 2 flow theory of plasticity with combined isotropic and kinematic hardening, where the back stress represents a tensor of orientational microstresses. It is assumed that the phase transformation part depends on the first and the second invariant of the tensor of crystallographic distortion, on the deviatoric part of the stress tensor, and on a special evolution parameter describing the rate of forming of a new phase. The elastic part of the rate of deformation tensor is connected with the objective rate of Cauchy stress through the tensor of elastic compliance. As a result, a general form of derived constitutive equations exhibits a similar structure as constitutive relations in finite deformation plasticity. (orig.)

  10. Gender disparities among the association between cumulative family-level stress & adolescent weight status.

    Science.gov (United States)

    Hernandez, Daphne C; Pressler, Emily

    2015-04-01

    To investigate precursors to gender-related obesity disparities by examining multiple family-level stress indices. Analyses was based on adolescents born between 1975 and 1991 to women from the 1979 National Longitudinal Study of Youth data set (N=4762). Three types of family-level stressors were captured from birth to age 15: family disruption and conflict, financial strain, and maternal risky health behaviors, along with a total cumulative risk index. Body mass index was constructed on reference criteria for children outlined by the Centers for Disease Control. Multivariate logistic regressions were conducted for the three types of family stressors and for the total cumulative index. The accumulation of family disruption and conflict and financial stress was positively related to female adolescents being overweight/obese. Childhood exposure to maternal risky health behaviors was positively associated with higher weight status for male adolescents. Total cumulative stress was related to overweight/obesity for females, but not males. Different family-level stress indices are associated with the weight status of female and male adolescents. Combining types of family-level stress into one cumulative index appears to mask these differences. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Examining Difference in Immigration Stress, Acculturation Stress and Mental Health Outcomes in Six Hispanic/Latino Nativity and Regional Groups.

    Science.gov (United States)

    Cervantes, Richard C; Gattamorta, Karina A; Berger-Cardoso, Jodi

    2018-02-27

    Little is known about the specific behavioral health impact of acculturation stressors that affect Hispanic/Latino immigrant sub-groups. These immigration-related stressors and traumatic events may have differential impact on depression depending on country/region of origin. Using a measure of immigration and acculturation stress, the current study sought to determine differences in the impact of stress on six sub-groups of Hispanic immigrants. Data on stress and depression were examined using a large, representative adult immigrant sample (N = 641). Controlling for age, gender and years in the US, factorial analysis of covariance revealed significant differences on total Hispanic Stress Inventory 2 (HSI2) stress appraisal scores based on country/region of origin. Pair wise comparisons between country/region of origin groups revealed that Mexicans had higher levels of stress compared to Cuban or Dominican immigrants. Several patterns of differential stress were also found within sub-domains of the HSI2. Using regression models, HSI2 stress appraisals and their interaction with country of origin proved to not be significant predictors of depression (PHQ9), while gender and age were significant. Differences in HSI2 stress that are based on nativity may be moderated by cultural resilience that ultimately serves a protective role to prevent the onset of depression.

  12. Stresses and residual stresses optical measurements systems evaluation; Avaliacao de sistemas opticos de medicao de tensoes e tensoes residuais em dutos

    Energy Technology Data Exchange (ETDEWEB)

    Peixoto Filho, Flavio Tito; Goncalves Junior, Armando Albertazzi [Universidade Federal de Santa Catarina (UFSC), Florianopolis, SC (Brazil). Lab. de Metrologia e Automatizacao (LABMETRO)

    2004-07-01

    There is always a constant concern about the pipelines' integrity. An important control parameter is the level of total mechanical stresses acting over the pipeline. However, the loading and residual stresses acting on a pipeline are not measured in the field as much as necessary. Technical difficulties and the high cost of the nowadays techniques and the hostile measurement conditions are the main reason for that. An alternative method has been developed at the Universidade Federal de Santa Catarina (UFSC) since 1992. A new optical measurement device is used to measure strains, mechanical stresses and residual stresses acting over the structure. A metrological and functional evaluation of this system is the main focus of this paper. (author)

  13. Predictors of Stress in College Students.

    Science.gov (United States)

    Saleh, Dalia; Camart, Nathalie; Romo, Lucia

    2017-01-01

    University students often face different stressful situations and preoccupations: the first contact with the university, the freedom of schedule organization, the selection of their master's degree, very selective fields, etc. The purpose of this study is to evaluate a model of vulnerability to stress in French college students. Stress factors were evaluated by a battery of six scales that was accessible online during 3 months. A total of 483 students, aged between 18 and 24 years (Mean = 20.23, standard deviation = 1.99), was included in the study. The results showed that 72.9, 86.3, and 79.3% of them were suffering from psychological distress, anxiety and depressive symptoms, respectively. More than half the sample was also suffering from low self-esteem (57.6%), little optimism (56.7%), and a low sense of self-efficacy (62.7%). Regression analyses revealed that life satisfaction, self-esteem, optimism, self-efficacy and psychological distress were the most important predictors of stress. These findings allow us to better understand stress-vulnerability factors in students and drive us to substantially consider them in prevention programs.

  14. Evaluation of an energy-based fatigue approach considering mean stress effects

    Energy Technology Data Exchange (ETDEWEB)

    Kabir, S. M. Humayun [Chittagong University of Engineering and Technology, Chittagong (Bangladesh); Yeo, Tae In [University of Ulsan, Ulsan (Korea, Republic of)

    2014-04-15

    In this paper, an attempt is made to extend the total strain energy approach for predicting the fatigue life subjected to mean stress under uniaxial state. The effects of means stress on the fatigue failure of a ferritic stainless steel and high pressure tube steel are studied under strain-controlled low cycle fatigue condition. Based on the fatigue results from different strain ratios, modified total strain energy density approach is proposed to account for the mean stress effects. The proposed damage parameter provides convenient means of evaluating fatigue life with mean stress effects considering the fact that the definitions used for measuring strain energies are the same as in the fully-reversed cycling (R = -1). A good agreement is observed between experimental life and predicted life using proposed approach. Two other mean stress models (Smith-Watson-Topper model and Morrow model) are also used to evaluate the low cycle fatigue data. Based on a simple statistical estimator, the proposed approach is compared with these models and is found realistic.

  15. Evaluation of an energy-based fatigue approach considering mean stress effects

    International Nuclear Information System (INIS)

    Kabir, S. M. Humayun; Yeo, Tae In

    2014-01-01

    In this paper, an attempt is made to extend the total strain energy approach for predicting the fatigue life subjected to mean stress under uniaxial state. The effects of means stress on the fatigue failure of a ferritic stainless steel and high pressure tube steel are studied under strain-controlled low cycle fatigue condition. Based on the fatigue results from different strain ratios, modified total strain energy density approach is proposed to account for the mean stress effects. The proposed damage parameter provides convenient means of evaluating fatigue life with mean stress effects considering the fact that the definitions used for measuring strain energies are the same as in the fully-reversed cycling (R = -1). A good agreement is observed between experimental life and predicted life using proposed approach. Two other mean stress models (Smith-Watson-Topper model and Morrow model) are also used to evaluate the low cycle fatigue data. Based on a simple statistical estimator, the proposed approach is compared with these models and is found realistic.

  16. Comparison of Total Antioxidant Capacity Oxidative Stress and Blood Lipoprotein Parameters in Volleyball Players and Sedentary

    Science.gov (United States)

    Gokhan, Ismail

    2013-01-01

    This study aims to measure, then compare sedentary blood lipoproteins, oxidant- antioxidant state and oxidative stress index in volleyball players. The experimental group of the research consists of regularly practising 20 boys between the ages of 12 and 17, and the control group comprises 32 children practising no particular sports branch, 12 of…

  17. Relationship Between Occupational Stress Dimensions and Sickness Absence Among a Gas Company Employees

    Directory of Open Access Journals (Sweden)

    Rezvan Zare

    2016-07-01

    Full Text Available Background: Working conditions have considerably changed and exposure to psychosocial risk factors, particularly occupational stress, has recently had an increasing trend. Studies have shown that sickness absence was the worst outcome of occupational stress. The present study aimed to assess the relationship between dimensions of occupational stress and sickness absence in a gas company in Boushehr, Iran. Methods: This cross-sectional study was conducted on 400 employees of a gas company, Boushehr, Iran who were selected through random sampling. Osipow occupational stress questionnaire was used to determine the participants’ stress levels. Then, the data were analyzed using descriptive statistics and Kruskal-Wallis test. Results: The participants’ mean of sickness absence was 2.164.57± days per year. Besides, 1.5%, 32.5%, 36.3%, and 29.8% of the participants had low, low to moderate, moderate to severe, and severe occupational stress, respectively. Additionally, the mean of total stress was moderate to severe among the study participants. This was also the case concerning the stress dimensions. The results revealed a significant relationship between the number of sickness absences and dimensions of occupational stress, including workload, role insufficiency, role conflict, responsibility, physical environment, and total stress (P=0.0001. Conclusion: The majority of the employees had high levels of occupational stress. Besides, a significant association was observed between the dimensions of occupational stress and sickness absence. Accordingly, to decrease the number of sickness absence, we should take measures to reduce occupational stress.

  18. Stress perceived by houseman in a hospital in northern Malaysia.

    Science.gov (United States)

    Gopalakrishnan, V; Umabalan, T; Affan, M; Zamri, A A; Kamal, A; Sandheep, S

    2016-02-01

    Being a houseman in Malaysian hospitals can be very stressful. Stress can affect decision making to a great extent while addressing the needs of the patient in an emergency setting. This necessitated a study to find out the main sources of stress among housemen. This was a cross-sectional descriptive study carried out among 55 housemen using a questionnaire on sources of stress. The data was analysed using SPSS version 17. A total of 16 factors leading to stress were studied among the housemen. Poor work and social life balance, annoying non-clinical personnel and medico-legal threats were among the top causes of stress. The factors leading to stress among housemen should be considered for effective working of the hospital and improving the workplace atmosphere for the housemen.

  19. Stress evaluation in hares (Lepus europaeus Pallas captured for traslocation

    Directory of Open Access Journals (Sweden)

    Antonio Lavazza

    2010-01-01

    Full Text Available With the aim to evaluate the capturing techniques some haematic and physiological parameters were studied to discrim- inate stressed hares from non stressed hares. A total of 66 wild hares (experimental group were sampled in 14 different non-hunting areas, where hares are usually captured for later release in low-density areas. In the same season a total of 30 hares (about 1 year old, reared in cages and thus showing a reduced fear of man, were sampled (control group. In each area the hares were captured by cours- ing with 3-4 dogs (greyhounds or lurches. The dogs were released by the different hunter teams to find and drive into trammel nets any hare that was seen running. After capture, the hares remained inside darkened, wooden capture-boxes for a variable period of time before blood drawing. For blood sample collection all the hares were physically restrained and their eyes immediately covered. Blood, always collected within 1-2 minutes, was drawn from the auricular vein. Blood samples (plasma were analysed for glucose, AST, ALT, CPK and cortisol concentrations. Body temperature, heart and respiratory rate, sex, and age were evaluated in each hare. The effect of origin, sex and age on haematic and physiolog- ical parameters was analysed by ANOVA. Every measured parameter of the hares bearing to the capture group or the control group (reared was then subjected to stepwise and to discriminant analysis, in order to select the groups of stressed (discriminated by the controls and non-stressed hares. CPK, AST and glucose were found to be the best parameters for distinguishing stressed from non-stressed hares. The intensive exercise suffered by the wild hares induced a depletion of energetic reserves, so that most of the captured hares showed lower glucose and higher CPK activity in the plasma, probably due to muscle damage (P< 0.05. After reclassi- fying the hares in the two groups of stressed and non stressed hares, the reference values (means

  20. The contribution of total and free iodothyronines to welfare maintenance and management stress coping in Ruminants and Equines: Physiological ranges and reference values.

    Science.gov (United States)

    Ferlazzo, Adriana; Cravana, Cristina; Fazio, Esterina; Medica, Pietro

    2018-06-01

    In order to acquire a pattern of thyroid involvement in welfare maintenance in Ruminants and Equines, this review summarizes data concerning the reference values of total and free iodothyronines and their modifications in physiological conditions and in different management conditions (pregnancy, lactation, weaning, growth, isolation, restraint, shearing, confinement and transportation). Thyroidal and extrathyroidal tissues efficiently respond to management practices, giving a differentiated contribution to circulating iodothyronine changes. The hormonal response could be mainly attributed to the intracellular deiodination of T 4 to T 3. Triiodothyronine (T 3 ) and free iodothyronines (fT 3 and fT 4 ) result more responsive to management stress, showing different pattern with species and to various conditions, as to environmental conditions in which activities are performed. Intrinsic seasonal changes of iodothyronines and a significant pregnancy effect for T 3 were recorded in mares. Higher, although not significant, T 3 and T 4 concentrations in barren than pregnant mares were observed in donkeys. A positive significant correlation between T 3 and T 4 was described only in pregnant donkeys. Moreover, a significant effect of season on T 3 and fT 3 changes was observed both in pregnant and barren donkeys. A significant lactating effect compared with nonlactating stage for T 3 and T 4 was recorded in mares. In growing foals, body weight (BW) and age were positively correlated with T 3 and negatively correlated with T 4 , fT 4 and fT 3 . Weaning effects were shown for T 3 and fT 4 concentrations, indicating that weaning represents a severe stress and the presence of conspecific does not reduce psychological stress in this phase. Lambs showed significant decreased T 3 and elevated T 4 concentrations two weeks after weaning, with higher concentrations in both males and females compared to 24 h. Significant positive correlations were observed between BW and T 4 , fT 3

  1. Calibration of Chaboche Model with a Memory Surface

    Directory of Open Access Journals (Sweden)

    Radim HALAMA

    2013-06-01

    Full Text Available This paper points out a sufficient description of the stress-strain behaviour of the Chaboche nonlinear kinematic hardening model only for materials with the Masing's behaviour, regardless of the number of backstress parts. Subsequently, there are presented two concepts of most widely used memory surfaces: Jiang-Sehitoglu concept (deviatoric plane and Chaboche concept (strain-space. On the base of experimental data of steel ST52 is then shown the possibility of capturing hysteresis loops and cyclic strain curve simultaneously in the usual range for low cycle fatigue calculations. A new model for cyclic hardening/softening behaviour modeling has been also developed based on the Jiang-Sehitoglu memory surface concept. Finally, there are formulated some recommendations for the use of individual models and the direction of further research in conclusions.

  2. Total synthesis of 4-F3t-neuroprostane and its 4-epimer

    Czech Academy of Sciences Publication Activity Database

    Auvinet, A. L.; Eignerová, Barbara; Guy, A.; Kotora, Martin; Durand, T.

    2009-01-01

    Roč. 50, č. 13 (2009), s. 1498-1500 ISSN 0040-4039 R&D Projects: GA MŠk 1M0508 Institutional research plan: CEZ:AV0Z40550506 Keywords : DPA * oxidative stress * neuroprostane * total synthesis Subject RIV: CC - Organic Chemistry Impact factor: 2.660, year: 2009

  3. Light energy dissipation under water stress conditions

    Energy Technology Data Exchange (ETDEWEB)

    Stuhlfauth, T.; Scheuermann, R.; Fock, H.P. (Universitaet Kaiserslautern (West Germany))

    1990-04-01

    Using {sup 14}CO{sub 2} gas exchange and metabolite analyses, stomatal as well as total internal CO{sub 2} uptake and evolution were estimated. Pulse modulated fluorescence was measured during induction and steady state of photosynthesis. Leaf water potential of Digitalis lanata EHRH. plants decreased to {minus}2.5 megapascals after withholding irrigation. By osmotic adjustment, leaves remained turgid and fully exposed to irradiance even at severe water stress. Due to the stress-induced reduction of stomatal conductance, the stomatal CO{sub 2} exchange was drastically reduced, whereas the total CO{sub 2} uptake and evolution were less affected. Stomatal closure induced an increase in the reassimilation of internally evolved CO{sub 2}. This CO{sub 2}-recycling consumes a significant amount of light energy in the form of ATP and reducing equivalents. As a consequence, the metabolic demand for light energy is only reduced by about 40%, whereas net photosynthesis is diminished by about 70% under severe stress conditions. By CO{sub 2} recycling, carbon flux, enzymatic substrate turnover and consumption of light energy were maintained at high levels, which enabled the plant to recover rapidly after rewatering. In stressed D. lanata plants a variable fluorescence quenching mechanism, termed coefficient of actinic light quenching, was observed. Besides water conservation, light energy dissipation is essential and involves regulated metabolic variations.

  4. Stress among dentists in Jeddah, Saudi Arabia

    International Nuclear Information System (INIS)

    Jamjoom, Hana M

    2008-01-01

    The objective of this study was to identify various stress factors affecting dentists and to evaluate their stress manifestations and stress management. A questionnaire was distributed among dentists residing in Jeddah, Saudi Arabia. The questionnaire classified stress factors into professional, patient-related, dental procedure-related, and office management factors. Sign and symptoms of stress manifestations and management were also evaluated. The sample included 80 females and 75 males, with 47% of them below the age of 30 years. Out of the total sample, the largest percentage (60.6%) were general practitioners, 47.7% had experience of less than 5 years and 32.2% had 11 years of experience. The highest mean scores of stress were related to professional factors and dental procedure-related factors. Among those, the main significant factors that caused stress in the surveyed sample were lack of time in relation to workload (76.1%), limited visibility and accessibility (67.7%). The most common manifestations of stress were nervousness (95%), musculoskeletal fatigue (72%) and anger (58%). Dentists predominantly managed their stress by praying and reading holy books (80%) and by spending time alone (75%) or with family and friends (70%). The most prevalent and significant causes of stress among dentists working in Jeddah, Saudi Arabia were professional in nature. Stress has been manifested by nervousness and musculoskeletal problem and was mainly managed by praying and spending time alone or with family and friends. (author)

  5. Temperature distribution and thermal stress

    Indian Academy of Sciences (India)

    Abstract. Thermal effects of a double-end-pumped cubic Nd:YVO4 laser crystal are investigated in this paper. A detailed analysis of temperature distribution and thermal stress in cubic crystal with circular shape pumping is discussed. It has been shown that by considering the total input powers as constant, the ...

  6. The major stressful life events and cancer: stress history and cancer.

    Science.gov (United States)

    Tas, Faruk; Karalar, Umran; Aliustaoglu, Mehmet; Keskin, Serkan; Can, Gulbeyaz; Cinar, Fatma Ebru

    2012-06-01

    The objective of this study was to analyze the extent of stressful life events' etiology and to compare socio-demographic and medical characteristics of the presence and absence of stress in Turkish cancer patients. Patients with cancer who attended ambulatory patient care units answered the questionnaires. Medical information was reviewed from chart data. The study population comprised 465 women (60.5%) and 303 men (39.5%), in total 768 cases. The median age was 53 years, ranging between 18 and 94. Three-hundred and twenty patients (41.7%) had at least one type of stress since last year of the time of initial diagnosis. Among patients had stress, the median number of stress modalities presented was 1 (range 1-6). Death, lack of livelihood, quarrel, illness, and debt almost always consisted of stress types. History of stress within last year was found more in women (66.3% vs. 56.5%, P = 0.006) and overweight patients (57.5% vs. 47.2%, P = 0.005). Similarly, among cancer types, only patients with breast cancer (41.9% vs. 31.7%, P = 0.04) had lived more stressful situation. However, the married patients (72.2% vs. 80.6%, P = 0.03) had less stress. Patients with gastric cancer had more frequent debt (29.0%, P history (21.4%, P = 0.001). Additionally, in lung cancer patients, their rate of livelihood difficulty was highly less than average (2.4%, P = 0.003). We found that overweight patients had more illness history (68.9% vs. 51.6%, P = 0.004), patients who were not working had more death history (89.7% vs. 78%, P = 0.01), and female patients had more quarrel history (78.2% vs. 60.5%, P = 0.002). Likewise, history of debt in patients who is a member of large family (56.2% vs. 27.4%, P = 0.01) was more frequent. Additionally, the lack of livelihood was prominent in urban patients (92.8% vs. 78.6%, P = 0.002) and in patients with low income (48.5% vs. 66.7%, P = 0.004). The question of whether or not psychological factors originated from stressful life events have an

  7. Nontraumatic tibial polyethylene insert cone fracture in mobile-bearing posterior-stabilized total knee arthroplasty

    Directory of Open Access Journals (Sweden)

    Yohei Tanikake

    2016-12-01

    Full Text Available A 72-year-old male patient underwent mobile-bearing posterior-stabilized total knee arthroplasty for osteoarthritis. He experienced a nontraumatic polyethylene tibial insert cone fracture 27 months after surgery. Scanning electron microscopy of the fracture surface of the tibial insert cone suggested progress of ductile breaking from the posterior toward the anterior of the cone due to repeated longitudinal bending stress, leading to fatigue breaking at the anterior side of the cone, followed by the tibial insert cone fracture at the anterior side of the cone, resulting in fracture at the base of the cone. This analysis shows the risk of tibial insert cone fracture due to longitudinal stress in mobile-bearing posterior-stabilized total knee arthroplasty in which an insert is designed to highly conform to the femoral component.

  8. Predictors of stress among parents in pediatric intensive care unit: a prospective observational study.

    Science.gov (United States)

    Aamir, Mohd; Mittal, Kundan; Kaushik, Jaya Shankar; Kashyap, Haripal; Kaur, Gurpreet

    2014-11-01

    To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU). A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at least 48 h duration were eligible for participation. At the end of 48 h, parental stress was assessed using parental stress scale (PSS:PICU) questionnaire which was administered to the parents. Baseline demographic and clinical parameters of children admitted to PICU were recorded. The parental stress was compared with demographic and clinical characteristics of children using appropriate statistical methods. A total of 49 parents were finally eligible for participation. Mean (SD) parental stress scores was highest in domains of procedures [1.52 (0.66)] and behavior and emotional [1.32 (0.42)] subscales. Mean (SD) total parental stress score among intubated children [1.31 (0.25)] was significantly more than among non intubated children [0.97 (0.26)] (p parental stress score were comparable in terms of gender (p = 0.15) and socioeconomic status (p = 0.32). On subscale analysis, it was found that professional communication is a significant stressor in age groups 0-12 mo [0.61(0.41)] (p = 0.02). It was observed that parents of intubated children were significantly stressed by the physical appearance of their children (p parental role (p = 0.002). Total parental stress score had a positive correlation with PRISM score (r = 0.308). Indian parents are stressed maximally with environment of PICU. Factor leading to parental stress was intubation status of the child and was not affected by gender or socio demographic profile of the parents.

  9. Parenting stress trajectories in mothers of very preterm infants to 2 years.

    Science.gov (United States)

    Gray, Peter H; Edwards, Dawn M; Gibbons, Kristen

    2018-01-01

    To examine levels of parenting stress in mothers of preterm and term infants when the children were 2 years old; to determine the trajectory of stress over three time periods and to examine the association of maternal and neonatal factors and developmental outcomes with parenting stress. It is a prospective longitudinal study to determine parenting stress in mothers of preterm and term infants with outcomes having been previously obtained at 4 and 12 months. At 2 years, 79 preterm mothers (96 babies) and 64 term mothers (77 babies) participated. The mothers completed the Parenting Stress Index-Short Form (PSI-SF), the Depression, Anxiety, Stress Scale (DASS) and the Child Behaviour Checklist (CBCL). The infants had a neurological examination and the Bayley-III scales were administered. The mean total PSI-SF at 2 years was significantly higher for the preterm group compared with the term group of mothers (p=0.007). There was a significant increase in the mean total PSI over time for the preterm mothers (pparenting stress and abnormal scores on the DASS (pparenting stress and maternal demographics, neonatal factors or Bayley-III results. Parenting stress in mothers of preterm infants continues to be high at 2 years having increased over time. Maternal mental health problems and infant behavioural issues contribute to the stress. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  10. Trait anxiety mediates the effect of stress exposure on post-traumatic stress disorder and depression risk in cardiac surgery patients.

    Science.gov (United States)

    Kok, Lotte; Sep, Milou S; Veldhuijzen, Dieuwke S; Cornelisse, Sandra; Nierich, Arno P; van der Maaten, Joost; Rosseel, Peter M; Hofland, Jan; Dieleman, Jan M; Vinkers, Christiaan H; Joëls, Marian; van Dijk, Diederik; Hillegers, Manon H

    2016-12-01

    Post-traumatic stress disorder (PTSD) and depression are common after cardiac surgery. Lifetime stress exposure and personality traits may influence the development of these psychiatric conditions. Self-reported rates of PTSD and depression and potential determinants (i.e., trait anxiety and stress exposure) were established 1.5 to 4 years after cardiac surgery. Data was available for 1125 out of 1244 (90.4%) participants. Multivariable linear regressions were conducted to investigate mediating and/or moderating effects of trait anxiety on the relationship between stress exposure, and PTSD and depression. Pre-planned subgroup analyses were performed for both sexes. PTSD and depression symptoms were present in 10.2% and 13.1% of the participants, respectively. Trait anxiety was a full mediator of the association between stress exposure and depression in both the total cohort and female and male subgroups. Moreover, trait anxiety partially mediated the relationship between stress exposure and PTSD in the full cohort and the male subgroup, whereas trait anxiety fully mediated this relationship in female patients. Trait anxiety did not play a moderating role in the total patient sample, nor after stratification on gender. The unequal distribution of male (78%) and female patients (22%) might limit the generalizability of our findings. Furthermore, risk factors were investigated retrospectively and with variable follow-up time. In cardiac surgery patients, trait anxiety was found to be an important mediator of postoperative PTSD and depression. Prospective research is necessary to verify whether these factors are reliable screening measures of individuals' vulnerability for psychopathology development after cardiac surgery. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Association between temperature and maternal stress during pregnancy.

    Science.gov (United States)

    Lin, Yanfen; Hu, Wenjing; Xu, Jian; Luo, Zhongcheng; Ye, Xiaofang; Yan, Chonghuai; Liu, Zhiwei; Tong, Shilu

    2017-10-01

    Maternal psychological stress during pregnancy has essentially been conceptualized as a teratogen. However, little is known about the effect of temperature on maternal stress during pregnancy. The aim of this study is to investigate the relationship between temperature and maternal stress during pregnancy. In 2010, a total of 1931 eligible pregnant women were enrolled across Shanghai from four prenatal-care clinics during their mid-to-late pregnancy. Maternal life-event stress and emotional stress levels during pregnancy were assessed by the "Life Event Scale for Pregnant Women" (LESPW) and "Symptom Checklist-90-Revised Scale" (SCL-90-R), respectively. Exposure to ambient temperature was evaluated based on daily regional average in different moving average and lag days. The generalized estimating equations were used to evaluate the relationship between daily average temperature/temperature difference and maternal stress. After adjusting for relevant confounders, an U-shaped relationship was observed between daily average temperature and maternal Global-Severity-Index (GSI) of the SCL-90-R. Cumulative exposures to extremely low temperatures (stress during pregnancy. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Correlation Between Fracture Network Properties and Stress Variability in Geological Media

    Science.gov (United States)

    Lei, Qinghua; Gao, Ke

    2018-05-01

    We quantitatively investigate the stress variability in fractured geological media under tectonic stresses. The fracture systems studied include synthetic fracture networks following power law length scaling and natural fracture patterns based on outcrop mapping. The stress field is derived from a finite-discrete element model, and its variability is analyzed using a set of mathematical formulations that honor the tensorial nature of stress data. We show that local stress perturbation, quantified by the Euclidean distance of a local stress tensor to the mean stress tensor, has a positive, linear correlation with local fracture intensity, defined as the total fracture length per unit area within a local sampling window. We also evaluate the stress dispersion of the entire stress field using the effective variance, that is, a scalar-valued measure of the overall stress variability. The results show that a well-connected fracture system under a critically stressed state exhibits strong local and global stress variabilities.

  13. Viscoelastic stress modeling in cementitious materials using constant viscoelastic hydration modulus

    NARCIS (Netherlands)

    Hansen, W.; Liu, Z.; Koenders, E.A.B.

    2014-01-01

    Viscoelastic stress modeling in ageing cementitious materials is of major importance in high performance concrete of low water cement ratio (e.g. w/c ~0.35) where crack resistance due to deformation restraint needs to be determined. Total stress analysis is complicated by the occurrence of internal

  14. Effects of temperature and Mo2C layer on stress and structural properties in CVD diamond film grown on Mo foil

    International Nuclear Information System (INIS)

    Long, Fen; Wei, Qiuping; Yu, Z.M.; Luo, Jiaqi; Zhang, Xiongwei; Long, Hangyu; Wu, Xianzhe

    2013-01-01

    Highlights: •Polycrystalline diamond films were grown on Mo foil substrates by HF-CVD. •We investigated the temperature dependence of the film stress for each sample. •We show that how the thermal stress and intrinsic stress affects the total stress. •The stress of Mo foil substrate obtained by XRD was investigated in this study. •The effect of Mo 2 C interface layer for stress of multilayer system was considered. -- Abstract: Polycrystalline diamond films have been prepared by hot-filament-assisted chemical vapor deposition (HFCVD) on Mo foils. The morphology, growth rate, phase composition, element distribution and residual stress of the films at different temperature were investigated by field-emission scanning electron microscopy, Raman spectrum, field emission electron probe microanalysis and X-ray diffraction. Results show that the residual stress of the diamond films is compressive. The thermal stress plays a decisive role in the total stress, while the intrinsic stress can change the trend of the total stress. The residual stress of substrate gradually changes from tensile stress to compressive stress with the increase of the deposited temperature. A Mo 2 C interlayer is formed during deposition process, and this layer has an important influence on the stresses of films and substrates

  15. JOB STRESS AMONG SCHOOL TEACHERS OF JAMMU REGION OF JAMMU AND KASHMIR

    OpenAIRE

    Sapana Sharma; Dr. Rajesh Kumar Sharma

    2017-01-01

    Stress is an organism’s total response to environmental demands or pressures. When stress was first studied in 1950’s, the term was used to denote both the causes and the experienced effects of these pressures .Stress may be good or bad. More recently, however, the word stressor has been used for the stimulus that provokes a stress response. The aim of the study was to find out the factor that creates stress among school teachers in Jammu region .The 60 respondents were selected by random s...

  16. Gravity-driven groundwater flow and slope failure potential: 1. Elastic effective-stress model

    Science.gov (United States)

    Iverson, Richard M.; Reid, Mark E.

    1992-01-01

    Hilly or mountainous topography influences gravity-driven groundwater flow and the consequent distribution of effective stress in shallow subsurface environments. Effective stress, in turn, influences the potential for slope failure. To evaluate these influences, we formulate a two-dimensional, steady state, poroelastic model. The governing equations incorporate groundwater effects as body forces, and they demonstrate that spatially uniform pore pressure changes do not influence effective stresses. We implement the model using two finite element codes. As an illustrative case, we calculate the groundwater flow field, total body force field, and effective stress field in a straight, homogeneous hillslope. The total body force and effective stress fields show that groundwater flow can influence shear stresses as well as effective normal stresses. In most parts of the hillslope, groundwater flow significantly increases the Coulomb failure potential Φ, which we define as the ratio of maximum shear stress to mean effective normal stress. Groundwater flow also shifts the locus of greatest failure potential toward the slope toe. However, the effects of groundwater flow on failure potential are less pronounced than might be anticipated on the basis of a simpler, one-dimensional, limit equilibrium analysis. This is a consequence of continuity, compatibility, and boundary constraints on the two-dimensional flow and stress fields, and it points to important differences between our elastic continuum model and limit equilibrium models commonly used to assess slope stability.

  17. A 3D finite element model to investigate prosthetic interface stresses of different posterior tibial slope.

    Science.gov (United States)

    Shen, Yi; Li, Xiaomiao; Fu, Xiaodong; Wang, Weili

    2015-11-01

    Posterior tibial slope that is created during proximal tibial resection in total knee arthroplasty has emerged as an important factor in the mechanics of the knee joint and the surgical outcome. But the ideal degree of posterior tibial slope for recovery of the knee joint function and preventions of complications remains controversial and should vary in different racial groups. The objective of this paper is to investigate the effects of posterior tibial slope on contact stresses in the tibial polyethylene component of total knee prostheses. Three-dimensional finite element analysis was used to calculate contact stresses in tibial polyethylene component of total knee prostheses subjected to a compressive load. The 3D finite element model of total knee prosthesis was constructed from the images produced by 3D scanning technology. Stresses in tibial polyethylene component were calculated with four different posterior tibial slopes (0°, 3°, 6° and 9°). The 3D finite element model of total knee prosthesis we presented was well validated. We found that the stress distribution in the polythene as evaluated by the distributions of the von Mises stress, the maximum principle stress, the minimum principle stress and the Cpress were more uniform with 3° and 6° posterior tibial slopes than with 0° and 9° posterior tibial slopes. Moreover, the peaks of the above stresses and trends of changes with increasing degree of knee flexion were more ideal with 3° and 6° posterior slopes. The results suggested that the tibial component inclination might be favourable to 7°-10° so far as the stress distribution is concerned. The range of the tibial component inclination also can decrease the wear of polyethylene. Chinese posterior tibial slope is bigger than in the West, and the current domestic use of prostheses is imported from the West, so their demands to tilt back bone cutting can lead to shorten the service life of prostheses; this experiment result is of important

  18. Ganoderma lucidum total triterpenes prevent γ-radiation induced oxidative stress in Swiss albino mice in vivo.

    Science.gov (United States)

    Smina, T P; Joseph, Jini; Janardhanan, K K

    2016-11-01

    The in vivo radio-protective effect of total triterpenes isolated from Ganoderma lucidum (Fr.) P. Karst was evaluated using Swiss albino mice, by pre-treatment with total triterpenes for 14 days, followed by a whole body exposure to γ-radiation. The activities of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), and the level of reduced glutathione (GSH) were analysed in liver and brain homogenates. The extent of lipid and protein peroxidation was also estimated in liver and brain homogenates after irradiation. Protection of radiation-induced DNA strand breaks in peripheral blood lymphocytes and bone marrow cells was assessed using the comet assay. Total triterpenes were highly effective in reducing the levels of lipid peroxidation and protein oxidation to near normal values in both liver and brain tissues. Total triterpenes, when administered in vivo, were also found to be successful in restoring the antioxidant enzyme activities and GSH level in liver and brain of irradiated mice. Administration of total triterpenes, prior to radiation exposure, significantly decreased the DNA strand breaks. The results of the present study thus revealed the potential therapeutic use of Ganoderma total triterpenes as an adjuvant in radiation therapy.

  19. Stressful life events and alcohol use among university students in ...

    African Journals Online (AJOL)

    In this study, the association between stressful life events and alcohol use among young adults pursuing university education in a university in Botswana was studied. A total of 312 young adults participated in the study (55.4% females, mean age = 21.58 (SD =1.87)). Student Stress Scale adapted from Holmes and Rahe's ...

  20. Executive function in cancer patients with posttraumatic stress disorder.

    Science.gov (United States)

    Yang, Juan; Guo, Juncheng; Jiang, Xiangling

    2017-03-01

    Background Cancer patients with posttraumatic stress disorder can lead to their noncompliant behaviors. However, less is known about the neurocognitive functioning of posttraumatic stress disorder in general cancer types or patient populations. The current study attempted to examine the prevalence of posttraumatic stress disorder and their relationships with executive function in individuals with cancer. Methods A total of 285 cancer patients with posttraumatic stress disorder and 150 healthy individuals were recruited for the present study. The Clinician Administered PTSD Scale, Tower of Hanoi, Wisconsin Card Sorting Test, and Wechsler Adult Intelligence Scale-Revised Chinese revision were administered to all participants. Results Significant differences in the score of Tower of Hanoi, Wisconsin Card Sorting Test, and Wechsler Adult Intelligence Scale-Revised Chinese revision were observed between the posttraumatic stress disorder group and the healthy control group ( p posttraumatic stress disorder symptoms and executive function. Conclusions These findings suggest that individuals with cancer-related posttraumatic stress disorder exhibit more severe impairment in executive function than healthy controls do.

  1. Posttraumatic stress disorder in bosnian war veterans: Analysis of stress events and risk factors

    Directory of Open Access Journals (Sweden)

    Kuljić Blagoje

    2004-01-01

    Full Text Available The aim of this study was to determine the incidence of Post-Traumatic Stress Disorder (PTSD, the characteristics of stress-related events, and the risk factors for the development of PTSD. The total patient sample consisted of 100 Bosnian war veterans. Watson’s PTSD module was used in establishing PTSD diagnosis. Patients fulfilled the following questionnaires: personal data form, Posttraumatic Symptom Scale PTSS-10 (Holen, Impact of Event Scale (Horowitz, Life Event Scale, and Eysenck Personality Inventory. PTSD was diagnosed in 30% of the examined patients. Larger number of stress-related events, particularly of those regarded as life-threatening, wounding/death of a close person, and material losses were more frequent in persons with PTSD. The risk factors for the development of PTSD in this study were: age (30-40, marital status (married, lower level of education, the front-line combat exposure, neurotic manifestations, family problems in childhood, and neuroticism.

  2. Stress distribution in two-dimensional silos

    Science.gov (United States)

    Blanco-Rodríguez, Rodolfo; Pérez-Ángel, Gabriel

    2018-01-01

    Simulations of a polydispersed two-dimensional silo were performed using molecular dynamics, with different numbers of grains reaching up to 64 000, verifying numerically the model derived by Janssen and also the main assumption that the walls carry part of the weight due to the static friction between grains with themselves and those with the silo's walls. We vary the friction coefficient, the radii dispersity, the silo width, and the size of grains. We find that the Janssen's model becomes less relevant as the the silo width increases since the behavior of the stresses becomes more hydrostatic. Likewise, we get the normal and tangential stress distribution on the walls evidencing the existence of points of maximum stress. We also obtained the stress matrix with which we observe zones of concentration of load, located always at a height around two thirds of the granular columns. Finally, we observe that the size of the grains affects the distribution of stresses, increasing the weight on the bottom and reducing the normal stress on the walls, as the grains are made smaller (for the same total mass of the granulate), giving again a more hydrostatic and therefore less Janssen-type behavior for the weight of the column.

  3. Subtalar joint stress imaging with tomosynthesis.

    Science.gov (United States)

    Teramoto, Atsushi; Watanabe, Kota; Takashima, Hiroyuki; Yamashita, Toshihiko

    2014-06-01

    The purpose of this study was to perform stress imaging of hindfoot inversion and eversion using tomosynthesis and to assess the subtalar joint range of motion (ROM) of healthy subjects. The subjects were 15 healthy volunteers with a mean age of 29.1 years. Coronal tomosynthesis stress imaging of the subtalar joint was performed in a total of 30 left and right ankles. A Telos stress device was used for the stress load, and the load was 150 N for both inversion and eversion. Tomographic images in which the posterior talocalcaneal joint could be confirmed on the neutral position images were used in measurements. The angle of the intersection formed by a line through the lateral articular facet of the posterior talocalcaneal joint and a line through the surface of the trochlea of the talus was measured. The mean change in the angle of the calcaneus with respect to the talus was 10.3 ± 4.8° with inversion stress and 5.0 ± 3.8° with eversion stress from the neutral position. The result was a clearer depiction of the subtalar joint, and inversion and eversion ROM of the subtalar joint was shown to be about 15° in healthy subjects. Diagnostic, Level IV.

  4. Study of Nitrate Stress in Desulfovibrio vulgaris Hildenborough Using iTRAQ Proteomics

    Energy Technology Data Exchange (ETDEWEB)

    Redding, A.M.; Mukhopadhyay, A.; Joyner, D.; Hazen, T.C.; Keasling, J.D.

    2006-10-12

    The response of Desulfovibrio vulgaris Hildenborough (DvH),a sulphate-reducing bacterium, to nitrate stress was examined usingquantitative proteomic analysis. DvH was stressed with 105 m M sodiumnitrate(NaNO3), a level that caused a 50 percent inhibition in growth.The protein profile of stressed cells was compared with that of cellsgrown in the absence of nitrate using the iTRAQ peptide labellingstrategy and tandem liquid chromatography separation coupled with massspectrometry (quadrupoletime-of-flight) detection. A total of 737 uniqueproteins were identified by two or more peptides, representing 22 percentof the total DvH proteome and spanning every functional category. Theresults indicate that this was a mild stress, as proteins involved incentral metabolism and the sulphate reduction pathway were unperturbed.Proteins involved in the nitrate reduction pathway increased. Increasesseen in transport systems for proline, glycine^ betaineandglutamateindicate that the NaNO3 exposure led to both salt stress and nitratestress.Up-regulation observed in oxidative stress response proteins (Rbr,RbO, etc.) and a large number of ABC transport systems as well as in iron^ sulphur -cluster-containing proteins, however, appear to be specific tonitrate exposure. Finally, a number of hypothetical proteins were amongthe most significant changers, indicating that there may be unknownmechanisms initiated upon nitrate stress in DvH.

  5. Pressure pain sensitivity as a marker for stress and pressure pain sensitivity-guided stress management in women with primary breast cancer.

    Science.gov (United States)

    Axelsson, Christen K; Ballegaard, Søren; Karpatschof, Benny; Schousen, Peer

    2014-08-01

    To validate (1) Pressure Pain Sensitivity (PPS) as a marker for stress and (2) a PPS-guided intervention in women with primary Breast Cancer (BC). (1) A total of 58 women with BC were examined before and after 6 months of intervention. A control group of 165 women office employees was divided in a High Stress Group (HSG, n = 37) and a Low Stress Group (LSG, n = 128) to evaluate the association between PPS, questionnaire-related Quality of Life (QOL) and self-evaluated stress. (2) A PPS-guided stress management program (n = 40) was compared to a Psychosocial Group Intervention (PGI, n = 91) and no treatment (n = 86) with respect to a European Organization for Research and Treatment of Cancer (EORTC) questionnaire measured QOL. (1) Resting PPS and changes in PPS during the intervention period correlated significantly to EORTC and Short Form 36 (SF 36) main scores: (all p stress scores (all p stress. (2) The PPS-guided intervention group improved EORTC main score, pain and nausea, when compared to the control groups (all p stress. PPS-guided intervention improved QOL in women with breast cancer.

  6. Development of the cortisol circadian rhythm in the light of stress early in life.

    Science.gov (United States)

    Simons, Sterre S H; Beijers, Roseriet; Cillessen, Antonius H N; de Weerth, Carolina

    2015-12-01

    The secretion of the stress hormone cortisol follows a diurnal circadian rhythm. There are indications that this rhythm is affected by stress early in life. This paper addresses the development of the cortisol circadian rhythm between 1 and 6 years of age, and the role of maternal stress and anxiety early in the child's life on this (developing) rhythm. Participants were 193 healthy mother-child dyads from a community sample. Self-reported maternal stress and anxiety and physiological stress (saliva cortisol), were assessed prenatally (gestational week 37). Postnatally, self-reported maternal stress and anxiety were measured at 3, 6, 12, 30, and 72 months. Saliva cortisol samples from the children were collected on two days (four times each day) at 12, 30, and 72 months of age. The total amount of cortisol during the day and the cortisol decline over the day were determined to indicate children's cortisol circadian rhythm. Multilevel analyses showed that the total amount of cortisol decreased between 1 and 6 years. Furthermore, more maternal pregnancy-specific stress was related to higher total amounts of cortisol in the child. Higher levels of early postnatal maternal anxiety were associated with flatter cortisol declines in children. Higher levels of early postnatal maternal daily hassles were associated with steeper child cortisol declines over the day. These results indicated developmental change in children's cortisol secretion from 1 to 6 years and associations between maternal stress and anxiety early in children's lives and children's cortisol circadian rhythm in early childhood. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Towards the Identification and Management of Stress in British Teachers.

    Science.gov (United States)

    Brown, Marie; Ralph, Sue

    In many countries today teaching has been identified as one of the most stressful occupations. The total annual cost of stress to the British Education Service has been estimated as high as 360 million U.S. dollars. The objective of this research study with teachers in the Department of Education at the University of Manchester was to identify…

  8. Elevated level of serum triglyceride among high risk stress bank ...

    African Journals Online (AJOL)

    The objective of this study was to estimate lipid profile among high risk stress bank employees' correlated with heart disorders in Riyadh, Saudi Arabia. A total of 129 patients with high risk stress employees were involved in this study, which were divided into 69 males and 60 females between the age of 25 to 55 years.

  9. Investigations on GSK-3β/NF-kB signaling in stress and stress adaptive behavior in electric foot shock subjected mice.

    Science.gov (United States)

    Bali, Anjana; Jaggi, Amteshwar Singh

    2016-04-01

    The present study was designed to explore the role of GSK-3β and NF-kB signaling in electric foot shock-induced stress and stress adaptation. Mice were subjected to foot shocks of 0.5mA intensity and 1s duration of 1h to produce acute stress. Animals were exposed to the same stressor for 5 days to induce stress adaptation. The behavioral alterations were assessed using the actophotometer, hole board, open field and social interaction tests. The serum corticosterone levels were assessed as a marker of the HPA axis. The levels of total GSK-3β, p-GSK-3β-S9 and p-NF-kB were determined in the hippocampus, frontal cortex and amygdala. Acute electric foot shock stress produced behavioral and biochemical changes; decreased the levels of p-GSK-3β-S9, produced no change in total GSK-3β levels and increased p-NF-kB levels in the brain. However, repeated exposure of foot shock stress restored the behavioral and biochemical changes along with normalization of p-GSK-3β-S9 and p-NF-kB levels. Administration of AR-A01, a selective GSK-3β inhibitor, or diethyldithiocarbamic acid (DDTC), a selective NF-kB inhibitor, diminished acute stress-induced behavioral and biochemical changes. Furthermore, AR-A014418 normalized acute stress-induced alterations in p-GSK-3β-S9 and p-NF-kB levels, however, DDTC selectively restored NF-kB levels without any change in p-GSK-3β-S9 levels. It probably suggests that NF-kB is a downstream mediator of the GSK-3 signaling cascade. It may conclude that acute stress associated decrease in p-GSK-3β-S9 and increase in p-NF-kB levels in the brain contribute in the development of behavioral and biochemical alterations and normalization of GSK-3β/NF-kB signaling may contribute in stress adaptive behavior in response to repeated electric foot shock-subjected mice. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. The effective stress concept in saturated sand-clay buffer

    International Nuclear Information System (INIS)

    Graham, J.; Oswell, J.M.; Gray, M.N.

    1992-01-01

    Tests were performed on mixtures of sand and bentonite, to investigate whether the behavior of the mixture can be expressed in terms of effective stresses, defined as the tensor difference between externally applied total stresses and pore water pressures measured outside the cell. Within acceptable bounds of experimental error, the tests show that effective stress can be used to describe consolidation and shear behaviour. However, because part of the effective stress in the clay is derived from net interparticle repulsive (unit) forces seated in diffuse double layers around aggregations of bentonite particles, the applicability of the concept has at this stage been restricted to conditions of constant volume (or possibly constant straining rate), constant chemistry, and constant temperature

  11. Qualità totale e mobilità totale Total Quality and Total Mobility

    Directory of Open Access Journals (Sweden)

    Giuseppe Trieste

    2010-05-01

    Full Text Available FIABA ONLUS (Italian Fund for Elimination of Architectural Barriers was founded in 2000 with the aim of promoting a culture of equal opportunities and, above all, it has as its main goal to involve public and private institutions to create a really accessible and usable environment for everyone. Total accessibility, Total usability and Total mobility are key indicators to define quality of life within cities. A supportive environment that is free of architectural, cultural and psychological barriers allows everyone to live with ease and universality. In fact, people who access to goods and services in the urban context can use to their advantage time and space, so they can do their activities and can maintain relationships that are deemed significant for their social life. The main aim of urban accessibility is to raise the comfort of space for citizens, eliminating all barriers that discriminate people, and prevent from an equality of opportunity. “FIABA FUND - City of ... for the removal of architectural barriers” is an idea of FIABA that has already affected many regions of Italy as Lazio, Lombardy, Campania, Abruzzi and Calabria. It is a National project which provides for opening a bank account in the cities of referring, in which for the first time, all together, individuals and private and public institutions can make a donation to fund initiatives for the removal of architectural barriers within its own territory for a real and effective total accessibility. Last February the fund was launched in Rome with the aim of achieving a Capital without barriers and a Town European model of accessibility and usability. Urban mobility is a prerequisite to access to goods and services, and to organize activities related to daily life. FIABA promotes the concept of sustainable mobility for all, supported by the European Commission’s White Paper. We need a cultural change in management and organization of public means, which might focus on

  12. Parenting stress in parents of children with refractory epilepsy before and after vagus nerve stimulation implantation

    Directory of Open Access Journals (Sweden)

    Sung-Tse Li

    2017-12-01

    Full Text Available Objectives: The purpose of this study was to evaluate parenting stress in parents of children with refractory epilepsy before and after their children received vagus nerve stimulation (VNS implantation. Methods: Parents of children with refractory epilepsy completed the Parenting Stress Index (PSI under a psychologist's assessment before and at least 12 months after their children received VNS implantation. The PSI questionnaire measures parenting stress in two domains; a parent domain with seven subscales, and a child domain with six. Age, gender, epilepsy comorbidity, VNS implantation date, seizure frequency, and anticonvulsant history before and after VNS implantation were obtained from reviews of medical charts. Results: In total, 30 parents completed the first and follow-up PSI questionnaires. Seventeen of their children (56.7% were boys. The children aged from 1 to 12 years (7.43 ± 3.59 years, mean ± SD. After VNS implantation, the mean total parenting stress scores decreased from 282.1 ± 38.0 to 272.4 ± 42.9. A significant decrease was found on the spouse subscale of the parent domain. For the parents of boys, the mean total parenting stress scores decreased significantly. The mean total parenting stress scores also decreased significantly for parents of epileptic children without autism and who did not taper off the number of different anticonvulsants used after VNS. Conclusions: VNS is an advisable choice to treat refractory epilepsy. Our study showed that 12 months or more after VNS implantation, seizure frequency and parenting stress typically decreased. However, in some special cases the parenting stress may increase, and external help may be required to support these patients and their parents. Key Words: children, refractory epilepsy, parenting stress, vagus nerve stimulation

  13. Takotsubo cardiomyopathy precipitated by negative pressure pulmonary oedema following total thyroidectomy

    Directory of Open Access Journals (Sweden)

    K S Bharathi

    2016-01-01

    Full Text Available 'Takotsubo cardiomyopathy (TCM' or 'stress cardiomyopathy' is a reversible cardiomyopathy that is precipitated by intense emotional or physical stress. This syndrome is characterised by symptoms mimicking acute coronary syndrome with transient systolic dysfunction associated with regional wall motion abnormalities, which extend beyond a single coronary vascular bed in the absence of obstructive coronary vascular disease. The presentation of TCM and myocardial infarction is similar with sudden onset of chest pain, breathlessness as well as abnormalities in both the electrocardiogram and cardiac enzymes. It is difficult to differentiate between the two until cardiac catheterisation establishes the diagnosis. We report a case of TCM in a post-menopausal female, precipitated by negative pressure pulmonary oedema following total thyroidectomy in whom timely cardiac catheterisation established the diagnosis and influenced the management. Heightened awareness of this unique cardiomyopathy is essential to have a high index of suspicion in at-risk population for the prompt diagnosis of stress-related cardiomyopathy syndromes occurring in the perioperative period.

  14. Double seismic zone in downgoing slabs and the viscosity of the mesosphere

    International Nuclear Information System (INIS)

    Sleep, N.H.

    1979-01-01

    The seismic zone beneath several island arcs between about 100 and 200 km depth consists of an upper zone having down-dip compression and a lower zone having down-dip tension. Several numerical models of the Aleutina arc were computed to test the hypothesis that these double seismic zones are due to sagging of the slab under its own weight. This sagging occurs because the asthenosphere (between about 100 and 200 km) provides little support or resistance to the slab, which is supported from below by the more viscous mesosphere and from above by the lithosphere. The viscosity of the mesosphere was constrained to the interval between 0.25 x 10 22 and 0.5 x 10 22 P by noting that the slab would have mainly down-dip compression at higher viscosities and mainly down-dip tension at lower viscosities. The deviatoric stress in the slab and the fault plane between the slab and the island arc is about 200--300 bars (expressed as shear stress). The models were calibrated to the observed depth and gravity anomalies in the trench

  15. Perceived work-related stress and early atherosclerotic changes in healthy employees.

    Science.gov (United States)

    Bugajska, Joanna; Widerszal-Bazyl, Maria; Radkiewicz, Piotr; Pasierski, Tomasz; Szulczyk, Grazyna Anna; Zabek, Jakub; Wojciechowska, Bozena; Jedryka-Góral, Anna

    2008-08-01

    This study was conducted to investigate the relationship between perceived work-related stress and preclinical atherosclerosis. A total of 100 managers and 50 office workers aged 35-65 participated in a questionnaire study. Individual, family and work-related stress risk factors and coping were evaluated in all the studied individuals. Serum levels of biochemical (total cholesterol, LDL, HDL, TG, glucose) and serological risk factors of atherosclerosis (anticardiolipin, anti-beta(2) GPI, anti-oxLDL, anti-HSP and anti-hsCRP antibodies) were evaluated. A computer analysis of B-mode ultrasound images was used to assess carotid artery intima-media thickness (IMT) and atherosclerotic plaque in carotid arteries. Statistical analysis was conducted with SPSS v. 11.5. The studied individuals showed average ranges of both the global stress level and of coping results. In 71% no changes were found in the ultrasound image and in 29% of individuals (43) the presence of plaque was shown. The mean value of the IMT measure was 0.0618 +/- 0.013 mm. IMT and plaque correlated negatively with the level of global work-related stress (r = -0.26; P related stress and coping, or between coping and IMT (P > 0.05), or between work-related stress and healthy lifestyle (no smoking, no excessive use of alcohol, high physical activity), or between healthy lifestyle and IMT (P > 0.05). Positive correlation between IMT and LDL and smoking did not result from higher stress reaction in the studied individuals. The explanation of the negative correlation between perceived work-related stress and preclinical atherosclerosis was not confirmed either by the subjects under high stress undertaking healthy protective activities or by their escaping into unhealthy behaviour. The most probable interpretation of the results is that in individuals with a low level of perceived work-related stress, somatization of stress takes place.

  16. Influence of stress on creep deformation properties of 9-12Cr ferritic creep resistant steels

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, K.; Sawada, K.; Kushima, H. [National Institute for Materials Science (Japan)

    2008-07-01

    Creep deformation property of 9-12Cr ferritic creep resistant steels was investigated. With decrease in stress, a magnitude of creep strain at the onset of accelerating creep stage decreased from about 2% in the short-term to less than 1% in the longterm. A time to 1% total strain was observed in the transient creep stage in the short term regime, however, it shifted to the accelerating creep stage in the long-term regime. Life fraction of the times to 1% creep strain and 1% total strain tended to increase with decrease in stress. Difference in stress dependence of the minimum creep rate was observed in the high- and low-stress regimes with a boundary condition of 50% of 0.2% offset yield stress. Stress dependence of the minimum creep rate in the high stress regime was equivalent to a strain rate dependence of the flow stress evaluated by tensile test, and a magnitude of stress exponent, n, in the high stress regime decreased with increase in temperature from 20 at 550 C to 10 at 700 C. On the other hand, n value in the low stress regime was about 5, and creep deformation in the low stress regime was considered to be controlled by dislocation climb. Creep rupture life was accurately predicted by a region splitting method by considering a change in stress dependence of creep deformation. (orig.)

  17. Monitoring Perceived Stress and Recovery in Relation to Cycling Performance in Female Athletes.

    Science.gov (United States)

    Otter, R T A; Brink, M S; van der Does, H T D; Lemmink, K A P M

    2016-01-01

    The purpose was to investigate perceived stress and recovery related to cycling performance of female athletes over one full year. 20 female athletes (age, 27±8 years; ˙VO2max, 50.3±4.6 mL·kg(-1)·min(-1)) were measured 8 times in one year to determine perceived stress and recovery (RESTQ-Sport) in relation to cycling performance (Lamberts and Lambert Submaximal Cycle Test (LSCT)). All 19 RESTQ-Sport scales were calculated and scores of the 4 main categories were determined (i. e., general stress, general recovery, sport-specific stress and sport-specific recovery). A balance score of total stress and recovery was calculated by recovery-stress. Power at the second stage (P80), third stage (P90) and heart rate recovery (HRR60 s) of the LSCT were determined as performance parameters. 110 RESTQ-Sports and LSCTs were analysed using a multilevel approach (random intercepts model). Higher self-efficacy was related to improvement of all performance parameters. Higher total recovery stress, and lower emotional stress were related to improvement of P90 and HRR60 s. Higher sport-specific recovery was related to P80, higher general stress, fatigue and physical complaints were related to decreased P90 and higher social stress and injury were related to decreased HRR60 s. Improved perceived recovery and stress contributed to an improved performance. Relevant information could be provided by monitoring changes in perceived stress and recovery of female athletes. © Georg Thieme Verlag KG Stuttgart · New York.

  18. Maternal active or passive smoking causes oxidative stress in placental tissue.

    Science.gov (United States)

    Aycicek, Ali; Varma, Mustafa; Ahmet, Koc; Abdurrahim, Kocyigit; Erel, Ozcan

    2011-05-01

    The aim of this study was to assess the influence of active and passive maternal smoking on placenta total oxidant/antioxidant status in term infants. The levels of cord blood total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) were measured in samples of fetal placental tissue, cord blood, and the maternal peripheral blood serum and from 19 mothers who were active smokers, 19 who were passive smokers, and 22 who were nonsmokers (not exposed to active or passive smoking). The pregnancies were between 37 and 40 weeks' gestation, were uncomplicated, and the infants were delivered vaginally. Birth weight and head circumference in the active smokers were significantly (P antioxidant balance in fetal placental tissue and causes potent oxidative stress.

  19. Methods for predicting isochronous stress-strain curves

    International Nuclear Information System (INIS)

    Kiyoshige, Masanori; Shimizu, Shigeki; Satoh, Keisuke.

    1976-01-01

    Isochronous stress-strain curves show the relation between stress and total strain at a certain temperature with time as a parameter, and they are drawn up from the creep test results at various stress levels at a definite temperature. The concept regarding the isochronous stress-strain curves was proposed by McVetty in 1930s, and has been used for the design of aero-engines. Recently the high temperature characteristics of materials are shown as the isochronous stress-strain curves in the design guide for the nuclear energy equipments and structures used in high temperature creep region. It is prescribed that these curves are used as the criteria for determining design stress intensity or the data for analyzing the superposed effects of creep and fatigue. In case of the isochronous stress-strain curves used for the design of nuclear energy equipments with very long service life, it is impractical to determine the curves directly from the results of long time creep test, accordingly the method of predicting long time stress-strain curves from short time creep test results must be established. The method proposed by the authors, for which the creep constitution equations taking the first and second creep stages into account are used, and the method using Larson-Miller parameter were studied, and it was found that both methods were reliable for the prediction. (Kako, I.)

  20. Validation of a radioimmunoassay for the determination of total corticosterone in rat plasma

    DEFF Research Database (Denmark)

    Pedersen, Tine Karen Hjort

    2000-01-01

    Abstract A radioimmunoassay (RIA) for total corticosterone (CORT) in rat plasma requiring a plasma volume of 2 μl was established. The importance of inactivating plasma corticosteroid-binding globulin (CBG), denatured by heat, before measuring CORT was shown. The method was evaluated and shown...... the blood sampling procedure. The result showed that the method had a capacity to detect CORT concentrations comparable with previous reported basal concentrations. Finally, the possible stress inducing effect of the blood sampling procedure was examined using two groups of male rats housed under either...... conventional or enriched environmental conditions. The result indicated that conventional environment housing induces slightly stressed animals compared to enriched housing. Enriched housing may provide an environment that makes it possible for rats to compensate for a stressful situation, i.e., the blood...

  1. Chinese Herbal Medicines as Potential Agents for Alleviation of Heat Stress in Poultry.

    Science.gov (United States)

    Shokryazdan, Parisa; Jahromi, Mohammad Faseleh; Md Saadand, Salwani; Ebrahimi, Mahdi; Idrus, Zulkifli; Zhou, Hailong; Diao, Xiao Ping; Liang, Juan Boo

    2017-01-01

    Heat stress negatively affects the productivity of chickens in commercial poultry farms in humid tropics. In this study, the concentrations and types of the antioxidant compounds of eight Chinese herbal medicines, which have previously demonstrated promising effects on suppressing heat stress as a mixture, were investigated using reversed-phase High Performance Liquid Chromatography, spectrophotometry, Liquid Chromatography Mass Spectrometry, and Gas-Liquid Chromatography. Our results provided the levels of phenolic compounds, total amounts of sugars, and total unsaturated fatty acids in the herbal extracts. Apart from the detection and quantification of the active ingredients of herbs that have the potential to mitigate heat stress in poultry, results of this study also provide useful data for developing an efficient and accurate formulation of the herbs' mixtures in order to induce positive effects against heat stress in in vivo studies.

  2. Chinese Herbal Medicines as Potential Agents for Alleviation of Heat Stress in Poultry

    Directory of Open Access Journals (Sweden)

    Parisa Shokryazdan

    2017-01-01

    Full Text Available Heat stress negatively affects the productivity of chickens in commercial poultry farms in humid tropics. In this study, the concentrations and types of the antioxidant compounds of eight Chinese herbal medicines, which have previously demonstrated promising effects on suppressing heat stress as a mixture, were investigated using reversed-phase High Performance Liquid Chromatography, spectrophotometry, Liquid Chromatography Mass Spectrometry, and Gas-Liquid Chromatography. Our results provided the levels of phenolic compounds, total amounts of sugars, and total unsaturated fatty acids in the herbal extracts. Apart from the detection and quantification of the active ingredients of herbs that have the potential to mitigate heat stress in poultry, results of this study also provide useful data for developing an efficient and accurate formulation of the herbs’ mixtures in order to induce positive effects against heat stress in in vivo studies.

  3. Canister displacement in KBS-3V. A theoretical study

    Energy Technology Data Exchange (ETDEWEB)

    Boergesson, Lennart [Clay Technology AB, Lund (Sweden); Hernelind, Jan [FEMTech AB, Vaesteraas (Sweden)

    2006-02-15

    models the deviatoric creep in the buffer during 100,000 years. The volumetric creep is not modelled, which thus may cause a slight underestimation of the canister displacement. The motive for excluding volumetric creep is that a canister settlement caused by volumetric creep will not change the total mass of bentonite under the canister but will only increase the density and is thus not judged to be a problem. Moreover, the volumetric creep is of the same order of magnitude as the deviatoric, which means that the canister displacement caused by this creep will be as insignificant as the deviatoric creep. The calculations show that the canister settlement is very small even at low swelling pressure and density. The base case corresponding to the expected final swelling pressure of the buffer 7,000 kPa yields a total settlement of the canister of only 0.35 mm for the fixed boundary case, while there is a heave of the canister of about 4.5 mm at the other case with 30/70 backfill due to the upwards swelling of the buffer. At reduced swelling pressure the settlement increases but is not more than about 23 mm at the very low swelling pressure 80 kPa for both cases. Another phenomenon that may affect the buffer is a reduction in strength or friction angle with time, which affects the degree of mobilized shear strength, which is a critical creep parameter. A reduced friction angle will reduce the strength and thus affect the degree of mobilized strength in a similar way as a reduced swelling pressure. So the reduction in shear strength can for the creep also correspond to a reduction in friction angle with kept initial density and swelling pressure. At the swelling pressure 80 kPa the deviatoric stress at failure is only 70 kPa, which for the swelling pressure 7,000 kPa corresponds to a friction angle of only 0.29 deg. This shows that not even a strong reduction in friction angle is a threat to the canister integrity. The conclusion is thus that the expected displacement of

  4. Canister displacement in KBS-3V. A theoretical study

    International Nuclear Information System (INIS)

    Boergesson, Lennart; Hernelind, Jan

    2006-02-01

    deviatoric creep in the buffer during 100,000 years. The volumetric creep is not modelled, which thus may cause a slight underestimation of the canister displacement. The motive for excluding volumetric creep is that a canister settlement caused by volumetric creep will not change the total mass of bentonite under the canister but will only increase the density and is thus not judged to be a problem. Moreover, the volumetric creep is of the same order of magnitude as the deviatoric, which means that the canister displacement caused by this creep will be as insignificant as the deviatoric creep. The calculations show that the canister settlement is very small even at low swelling pressure and density. The base case corresponding to the expected final swelling pressure of the buffer 7,000 kPa yields a total settlement of the canister of only 0.35 mm for the fixed boundary case, while there is a heave of the canister of about 4.5 mm at the other case with 30/70 backfill due to the upwards swelling of the buffer. At reduced swelling pressure the settlement increases but is not more than about 23 mm at the very low swelling pressure 80 kPa for both cases. Another phenomenon that may affect the buffer is a reduction in strength or friction angle with time, which affects the degree of mobilized shear strength, which is a critical creep parameter. A reduced friction angle will reduce the strength and thus affect the degree of mobilized strength in a similar way as a reduced swelling pressure. So the reduction in shear strength can for the creep also correspond to a reduction in friction angle with kept initial density and swelling pressure. At the swelling pressure 80 kPa the deviatoric stress at failure is only 70 kPa, which for the swelling pressure 7,000 kPa corresponds to a friction angle of only 0.29 deg. This shows that not even a strong reduction in friction angle is a threat to the canister integrity. The conclusion is thus that the expected displacement of the canister from

  5. Acute Cold / Restraint Stress in Castrated Rats

    Directory of Open Access Journals (Sweden)

    Farideh Zafari Zangeneh

    2008-09-01

    Full Text Available Objective: The present study aimed to determine whether castration altered osmotically stimulated vasopressin (VP release and urinary volume and what is the role of endocrine-stress axis in this process.Materials and methods: Totally 108 mice were studied in two main groups of castrated (n=78 and control (n=30. Each group was extracted by acute cold stress (4◦C for 2h/day, restraint stress (by syringes 60cc 2h/day and cold/restraint stress. The castrated group was treated in sub groups of testosterone, control (sesame oil as vehicle of testosterone. Propranolol as blocker of sympathetic nervous system was given to both groups of castrated mice and main control.Results: Our results showed that, there is interactions between testosterone and sympathetic nervous system on vasopressin, because urine volume was decreased only in testoctomized mice with cold/restraint and cold stress (P<0.001; propranolol as the antagonist of sympathetic nervous system could block and increase urine volume in castrated mice. This increased volume of urine was due to acute cold stress, not restraint stress (p<0.001. The role of testosterone, noradrenalin (NA and Vasopressin (VP in the acute cold stress is confirmed, because testosterone could return the effect of decreased urine volume in control group (P<0.001. Conclusion: Considering the effect of cold/restraint stress on urinary volume in castrated mice shows that there is interaction between sex hormone (testosterone, vasopressin and adrenergic systems.

  6. Occupational stress and its predictors in radiographers

    Energy Technology Data Exchange (ETDEWEB)

    Rutter, D.R. [Centre for Research in Health Behaviour, Department of Psychology, University of Kent, Keynes College, Canterbury CT2 7NP (United Kingdom)], E-mail: d.r.rutter@kent.ac.uk; Lovegrove, M.J. [Department of Allied Health Professions, London South Bank University, London SE1 0AA (United Kingdom)

    2008-05-15

    Purpose: The purpose of this study was to establish the level of occupational stress in UK NHS radiographers, and to examine its causes. A total of more than 1600 radiographers sampled nationally completed a postal questionnaire. Four groups were represented - mammography, diagnostics, radiotherapy, and ultrasound - and both junior staff and superintendents were examined. Method: The questionnaire measured role ambiguity, role conflict, work problems, social support from colleagues, and perceived stress. Results: Levels of perceived stress were high in all four groups. The mean was significantly lower in the mammography group than the others, however, and junior staff reported lower levels than superintendents. Role ambiguity, role conflict and work problems all contributed significantly to stress, but the effects were sometimes buffered by social support from colleagues. Conclusion: The implications of the findings are discussed for theory and for policy and practice: occupational stress was predicted by intrinsic features of the job; the levels were similar to those reported by other NHS professionals; and the pattern of findings suggests possible ways to intervene to reduce it.

  7. Occupational stress and its predictors in radiographers

    International Nuclear Information System (INIS)

    Rutter, D.R.; Lovegrove, M.J.

    2008-01-01

    Purpose: The purpose of this study was to establish the level of occupational stress in UK NHS radiographers, and to examine its causes. A total of more than 1600 radiographers sampled nationally completed a postal questionnaire. Four groups were represented - mammography, diagnostics, radiotherapy, and ultrasound - and both junior staff and superintendents were examined. Method: The questionnaire measured role ambiguity, role conflict, work problems, social support from colleagues, and perceived stress. Results: Levels of perceived stress were high in all four groups. The mean was significantly lower in the mammography group than the others, however, and junior staff reported lower levels than superintendents. Role ambiguity, role conflict and work problems all contributed significantly to stress, but the effects were sometimes buffered by social support from colleagues. Conclusion: The implications of the findings are discussed for theory and for policy and practice: occupational stress was predicted by intrinsic features of the job; the levels were similar to those reported by other NHS professionals; and the pattern of findings suggests possible ways to intervene to reduce it

  8. Nitro-oxidative stress, VEGF and MMP-9 in patients with cirrhotic and non-cirrhotic portal hypertension.

    Science.gov (United States)

    Muti, Leon Adrian; Pârvu, Alina Elena; Crăciun, Alexandra M; Miron, Nicolae; Acalovschi, Monica

    2015-01-01

    Nitro-oxidative stress may have pathophysiological consequences. The study aimed to assess the nitro-oxidative stress, the vascular growth factor, and metalloproteinase-9 levels in patients with noncirrohic and cirrhotic portal hypertension. Patients with noncirrhotic portal hypertension (n=50) and cirrhotic portal hypertension (n=50) from the 3rd Medical Clinic in Cluj-Napoca Romania were prospectively enrolled between October 2004 and October 2006. A control group of healthy volunteers (n=50) was also evaluated. Nitro-oxidative stress was assessed by measuring serum concentration of nitrites and nitrate, 3-nitrotyrosine, total oxidative status, total antioxidant reactivity, and oxidative stress index. Serum vascular growth factor and matrix metalloproteinase-9 were also determined. Serum nitrites and nitrate levels significantly increased in both noncirrhotic (pportal hypertension (p=0.057). 3-nitrotyrosine also increased in noncirrhotic (p=0.001) and cirrhotic portal hypertension patients (p=0.014). Total oxidative status showed a significant increase in noncirrhotic (pportal hypertension (pportal hypertension (pportal hypertension a significant systemic nitro-oxidative stress was found, correlated with an increase of VEGF. MMP-9 decreased in noncirrhotic portal hypertension.

  9. Preliminary Investigation of a Stress Prevention and Mindfulness Group for Teachers

    Science.gov (United States)

    Reiser, Jenson E.; McCarthy, Christopher J.

    2018-01-01

    This exploratory study evaluated a short-term (6-8 weeks) psychoeducation and support group for teachers focused on stress prevention and mindfulness (labeled SPAM group). A total of 4 groups were implemented in different schools, and evaluation was conducted with quantitative (pre- and post-measures of teacher vulnerability to stress, job…

  10. Impact of different analgesic depths and abdominal trauma of different severities on stress and recovery of rats undergoing total intravenous anesthesia

    Directory of Open Access Journals (Sweden)

    Huang HM

    2017-05-01

    Full Text Available Hai-ming Huang,1,2 Jun Cao,3 Lin-mei Zhu,4 Yu-qing Chen,2 Fu-ding Lu,2 Hong-wei Cai1 1Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, 2Department of Anesthesiology, 3Department of Hepatic and Biliary Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 4Department of Obstetrics and Gynecology, Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China Abstract: A number of animal models have been developed to examine the pathophysiological consequences of surgical procedures, but anesthetic methods, monitoring, and management measures in these models are very different from those used in humans. This study was designed to create a rat model of abdominal surgery using anesthetic methods and perioperative treatment similar to those used in the clinic and to investigate the effects of different injury severities and depths of anesthesia and analgesia on surgical stress and postoperative recovery. Abdominal skin/muscle incision was compared with exploratory laparotomy in rats under propofol intravenous anesthesia, accompanied by perioperative measures such as oxygen inhalation, fluid infusion, warmth, blood gas analysis, and infection prevention. Stress indices (mean arterial pressure, heart rate, blood glucose, and plasma corticosterone were monitored during anesthesia and surgery, and recovery indicators (body weight, food consumption, and pain were measured after surgery. In addition, animals undergoing laparotomy were subjected to low and high dosages of propofol and sufentanil, in order to examine the relationship between anesthetic and analgesic depth and stress on recovery. Exploratory laparotomy induced a greater stress response and caused slower postoperative recovery as measured than somatic injury. High-dose sufentanil downregulated plasma corticosterone and improved postoperative recovery more effectively than high-dose propofol (P<0

  11. Simvastatin and oxidative stress in humans

    DEFF Research Database (Denmark)

    Rasmussen, Sanne Tofte; Andersen, Jon Thor Trærup; Nielsen, Torben Kjær

    2016-01-01

    in mitochondrial respiratory complexes I and II and might thereby reduce the formation of reactive oxygen species, which have been implicated in the pathogenesis of arteriosclerosis. Therefore, we hypothesized that simvastatin may reduce oxidative stress in humans in vivo. We conducted a randomized, double......-blinded, placebo-controlled study in which subjects were treated with either 40 mg of simvastatin or placebo for 14 days. The endpoints were six biomarkers for oxidative stress, which represent intracellular oxidative stress to nucleic acids, lipid peroxidation and plasma antioxidants, that were measured in urine.......1% in the placebo group for DNA oxidation and 7.3% in the simvastatin group compared to 3.4% in the placebo group. The differences in biomarkers related to plasma were not statistically significant between the treatments groups, with the exception of total vitamin E levels, which, as expected, were reduced...

  12. Modular femoral component for conversion of previous hip surgery in total hip arthroplasty.

    Science.gov (United States)

    Goldstein, Wayne M; Branson, Jill J

    2005-09-01

    The conversion of previous hip surgery to total hip arthroplasty creates a durable construct that is anatomically accurate. Most femoral components with either cemented or cementless design have a fixed tapered proximal shape. The proximal femoral anatomy is changed due to previous hip surgery for fixation of an intertrochanteric hip fracture, proximal femoral osteotomy, or a fibular allograft for avascular necrosis. The modular S-ROM (DePuy Orthopaedics Inc., Warsaw, Ind) hip stem accommodates these issues and independently prepares the proximal and distal portion of the femur. In preparation and implantation, the S-ROM hip stem creates less hoop stresses on potentially fragile stress risers from screws and thin bone. The S-ROM hip stem also prepares a previously distorted anatomy by milling through cortical bone that can occlude the femoral medullar canals and recreate proper femoral anteversion and reduces the risk of intraoperative or postoperative periprosthetic fracture due to the flexible titanium-slotted stem. The S-ROM femoral stem is recommended for challenging total hip reconstructions.

  13. Stress relaxation in a ferrofluid with clustered nanoparticles

    International Nuclear Information System (INIS)

    Borin, Dmitry Yu; Odenbach, Stefan; Zubarev, Andrey Yu; Chirikov, Dmitry N

    2014-01-01

    The formation of structures in a ferrofluid by an applied magnetic field causes various changes in the rheological behaviour of the ferrofluid. A ferrofluid based on clustered iron nanoparticles was investigated. We experimentally and theoretically consider stress relaxation in the ferrofluid under the influence of a magnetic field, when the flow is suddenly interrupted. It is shown that the residual stress observed in the fluid after the relaxation is correlated with the measured and theoretically predicted magnetic field-induced yield stress. Furthermore, we have shown that the total macroscopic stress in the ferrofluid after the flow is interrupted is defined by the presence of both linear chains and dense, drop-like bulk aggregates. The proposed theoretical approach is consistent with the experimentally observed behaviour, despite a number of simplifications which have been made in the formulation of the model. Thus, the obtained results contribute a lot to the understanding of the complex, magnetic field-induced rheological properties of magnetic colloids near the yield stress point. (paper)

  14. Development of the Seasonal Migrant Agricultural Worker Stress Scale in Sanliurfa, Southeast Turkey.

    Science.gov (United States)

    Simsek, Zeynep; Ersin, Fatma; Kirmizitoprak, Evin

    2016-01-01

    Stress is one of the main causes of health problems, especially mental disorders. These health problems cause a significant amount of ability loss and increase cost. It is estimated that by 2020, mental disorders will constitute 15% of the total disease burden, and depression will rank second only after ischemic heart disease. Environmental experiences are paramount in increasing the liability of mental disorders in those who constantly face sustained high levels of stress. The objective of this study was to develop a stress scale for seasonal migrant agricultural workers aged 18 years and older. The sample consisted of 270 randomly selected seasonal migrant agricultural workers. The average age of the participants was 33.1 ± 14, and 50.7% were male. The Cronbach alpha coefficient and test-retest methods were used for reliability analyses. Although the factor analysis was performed for the structure validity of the scale, the Kaiser-Meyer-Olkin coefficient and Bartlett test were used to determine the convenience of the data for the factor analysis. In the reliability analyses, the Cronbach alpha coefficient of internal consistency was calculated as .96, and the test-retest reliability coefficient was .81. In the exploratory factor analysis for validity of the scale, four factors were obtained, and the factors represented workplace physical conditions (25.7% of the total variance), workplace psychosocial and economic factors (19.3% of the total variance), workplace health problems (15.2% of the total variance), and school problems (10.1% of the total variance). The four factors explained 70.3% of the total variance. As a result of the expert opinions and analyses, a stress scale with 48 items was developed. The highest score to be obtained from the scale was 144, and the lowest score was 0. The increase in the score indicates the increase in the stress levels. The findings show that the scale is a valid and reliable assessment instrument that can be used in

  15. Food cravings mediate the relationship between chronic stress and body mass index.

    Science.gov (United States)

    Chao, Ariana; Grilo, Carlos M; White, Marney A; Sinha, Rajita

    2015-06-01

    This study examined the relationships between chronic stress, food cravings, and body mass index. A community-based sample of adults (N = 619) completed a comprehensive assessment battery and heights and weights were measured. Chronic stress had a significant direct effect on food cravings, and food cravings had a significant direct effect on body mass index. The total effect of chronic stress on body mass index was significant. Food cravings partially mediated the relationship between chronic stress and body mass index. These findings are consistent with research that chronic stress may potentiate motivation for rewarding substances and behaviors and indicate that high food cravings may contribute to stress-related weight gain. © The Author(s) 2015.

  16. Exercise-induced rib stress fractures: influence of reduced bone mineral density

    DEFF Research Database (Denmark)

    Vinther, Anders; Kanstrup, Inge-Lis; Christiansen, Erik

    2005-01-01

    study investigated BMD in seven Danish national team rowers with previous rib stress fracture (RSF) and 7 controls (C) matched for gender, age, height, weight and training experience. Total body scan and specific scans of the lumbar spine (L2-L4), femoral neck and distal radius were performed using......Exercise-induced rib stress fractures have been reported frequently in elite rowers during the past decade. The etiology of rib stress fractures is unclear, but low bone mineral density (BMD) has been suggested to be a potential risk factor for stress fractures in weight-bearing bones. The present...... density may be a potential risk factor for the development of exercise-induced rib stress fractures in elite rowers....

  17. Interaction between the RGS6 gene and psychosocial stress on obesity-related traits.

    Science.gov (United States)

    Kim, Hyun-Jin; Min, Jin-Young; Min, Kyoung-Bok

    2017-03-31

    Obesity is a major risk factor for chronic diseases and arises from the interactions between environmental factors and multiple genes. Psychosocial stress may affect the risk for obesity, modifying food intake and choice. A recent study suggested regulator of G-protein signaling 6 (RGS6) as a novel candidate gene for obesity in terms of reward-related feeding under stress. In this study, we tried to verify the unidentified connection between RGS6 and human obesity with psychosocial stress in a Korean population. A total of 1,462 adult subjects, who participated in the Korean Association Resource cohort project, were included for this analysis. Obesity-related traits including waist circumference, body mass index, and visceral adipose tissue were recorded. A total of 4 intronic SNPs for the RGS6 gene were used for this study. We found that interactions between SNP rs2239219 and psychosocial stress are significantly associated with abdominal obesity (p = 0.007). As risk allele of this SNP increased, prevalence of abdominal obesity under high-stress conditions gradually increased (p = 0.013). However, we found no SNPs-by-stress interaction effect on other adiposity phenotypes. This study suggests that RGS6 is closely linked to stress-induced abdominal obesity in Korean adults.

  18. Total antioxidant capacity and total oxidant status of synovial fluids in patients with temporomandibular joint pain and dysfunction.

    Science.gov (United States)

    Etöz, Osman A; Akçay, Hüseyin; Neşelioğlu, Salim; Erel, Özcan; Alkan, Alper

    2012-12-01

    The objective of this study was to investigate whether a relationship exists between total antioxidant capacity (TAC) and total oxidant status (TOS) of synovial fluids (SFs) of temporomandibular joint (TMJ) pain patients with pain and dysfunction. Forty-two patients with TMJ pain were included in this study. TAC and TOS values of SFs were measured with a novel colorimetric method. Independent t test and correlations were used to analyze the data. TAC of SFs in patients with TMJ pain and limited mouth opening (LMO; n = 21) were significantly lower (P = 0.03) than patients without LMO (n = 21). TOS of SF was negatively correlated with duration of the disease. There was no correlation between TAC, TOS, and VAS scores of the patients as well as age and maximum mouth opening values. Antioxidant response to oxidative changes (TAC and TOS) in SF decreased as the stage of dysfunction increased. Local administration of antioxidant agents might be considered in management of TMJ pain and dysfunction to prevent possible increased oxidative stress.

  19. Exploring Temporal Patterns of Stress in Adolescent Girls with Headache.

    Science.gov (United States)

    Björling, Elin A; Singh, Narayan

    2017-02-01

    As part of a larger study on perceived stress and headaches in 2009, momentary perceived stress, head pain levels and stress-related symptom data were collected. This paper explores a temporal analysis of the patterns of stress, as well as an analysis of momentary and retrospective stress-related symptoms compared by level of headache activity. Adolescent girls (N = 31) ages 14-18 were randomly cued by electronic diaries 7 times per day over a 21-day period responding to momentary questions about level of head pain, perceived stress and stress-related symptoms. Multivariate general linear modelling was used to determine significant differences among headache groups in relation to temporal patterns of stress. Significant headache group differences were found on retrospective and momentary stress-related symptom measures. A total of 2841 diary responses captured stress levels, head pain and related symptoms. The chronic headache (CH) group reported the highest levels of hourly and daily stress, followed by the moderate headache (MH) and low headache (LH) groups. Patterns of stress for the three headache groups were statistically distinct, illustrating increased stress in girls with more frequent head pain. This evidence suggests that because of increased stress, girls with recurrent head pain are likely a vulnerable population who may benefit from stress-reducing interventions. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  20. Perceived Support as a Predictor of Acculturative Stress among International Students in the United States

    Science.gov (United States)

    Bai, Jieru

    2016-01-01

    A quantitative study was conducted to measure the acculturative stress of international students and investigate the predictors of acculturative stress. A total of 186 students participated in the survey. Results showed that 22.4% of the students in this study exceeded the normal stress level and might need counseling or psychological…

  1. [Relationship of job stress with job burnout and quality of work life in workers for offshore oil platforms].

    Science.gov (United States)

    Zhang, Y; Liu, X L; Wei, T D; Lan, Y J

    2017-03-20

    Objective: To evaluate the current status of job burnout and qual ity of work life (QWL) in workers for offshore oil platforms, and to analyze the relationship of job stress with job burnout and QWL and the direct and indirect effects of job stress on QWL. Methods: Cluster random sampling was used to select 382 work-ers for 8 oil platforms of China National Offshore Oil Corporation in October 2015. A self - designed questionnaire was used to collect the individual characteristics of subjects. The Quality of Work Life Scale (QWL7 - 32) , Occupa-tional Stress Inventory - Revised Edition (OSI - R) , and Maslach Burnout Inventory - General Survey (MBI - GS) were used to investigate the QWL, job stress, and job burnout of subjects. Results: Among all the workers for offshore oil platforms, 87.2% had mild job burnout. The total QWL score was 116.01 ± 16.73; 8.3% of the workers had poor QWL, and 68.5% had moderate QWL. QWL was reduced with heavier task, vaguer task, and increasing mental stress and physical stress ( P stress had di-rect and indirect effects on QWL; stress reaction had the most effect on QWL (total effect size - 0.509) , followed by social support (total effect size 0.444) . Conclusion: Most workers for offshore oil platforms have mild job burn-out and moderate QWL. Job stress is associated with job burnout and QWL, and stress reaction and social support have relatively high influence on QWL.

  2. Work-Family Conflict and Work-Related Attitude: The Mediating Effects of Stress Reactions

    OpenAIRE

    Siti Aisyah Binti Panatik; Siti Khadijah Binti Zainal Badri; Azizah Binti Rajab; Rosman Bin Mohd. Yusof

    2012-01-01

    This study aims to investigate the relationship between work-family conflict (i.e.work-to-family and family-to-work) and work-related attitudes (i.e. job satisfaction,affective commitment and turnover intentions) among academician in Malaysia.Mediationeffects of stress reactionswhich arebehavioral stress, somatic stress andcognitive stresswere also tested. A survey method using questionnaire was utilizedto obtain the data. A total of 267 respondents were participated, giving...

  3. Irradiation effects on the adrenal gland of rats undergoing inanition stress

    International Nuclear Information System (INIS)

    Hasan, S.S.; Chaturvedi, P.K.

    1985-01-01

    The effect of total body x-irradiation was studied on rats under inanition stress. In response to irradiation an increase in the activity of cortex and medulla was noted in inanition stress administered rats rather than in the normally fed animals. Similarly, rising levels of urinary catecholamines and 5-hydroxytryptamine were observed in the starved animals after irradiation. (author)

  4. The impact of professional identity on role stress in nursing students: A cross-sectional study.

    Science.gov (United States)

    Sun, Li; Gao, Ying; Yang, Juan; Zang, Xiao-Ying; Wang, Yao-Gang

    2016-11-01

    As newcomers to the clinical workplace, nursing students will encounter a high degree of role stress, which is an important predictor of burnout and engagement. Professional identity is theorised to be a key factor in providing high-quality care to improve patient outcomes and is thought to mediate the negative effects of a high-stress workplace and improve clinical performance and job retention. To investigate the level of nursing students' professional identity and role stress at the end of the first sub-internship, and to explore the impact of the nursing students' professional identity and other characteristics on role stress. A cross-sectional study. Three nursing schools in China. Nursing students after a 6-month sub-internship in a general hospital (n=474). The Role Stress Scale (score range: 12-60) and the Professional Identity Questionnaire for Nursing students (score range: 17-85) were used to investigate the levels of nursing students' role stress and professional identity. Higher scores indicated higher levels of role stress and professional identity. Basic demographic information about the nursing students was collected. The Pearson correlation, point-biserial correlation and multiple linear regression analysis were used to analyse the data. The mean total scores of the Role Stress Scale and Professional Identity Questionnaire for Nursing Students were 34.04 (SD=6.57) and 57.63 (SD=9.63), respectively. In the bivariate analyses, the following independent variables were found to be significantly associated with the total score of the Role Stress Scale: the total score of the Professional Identity Questionnaire for Nursing Students (r=-0.295, pNursing Students (standardised coefficient Beta: -0.260, pStress Scale. The multiple linear regression model explained 18.2% (adjusted R 2 scores 16.5%) of the Role Stress Scale scores variance. The nursing students' level of role stress at the end of the first sub-internship was high. The students with higher

  5. Stress fractures of ankle and wrist in childhood: nature and frequency

    International Nuclear Information System (INIS)

    Oestreich, Alan E.; Bhojwani, Nicholas

    2010-01-01

    Stress fractures of many etiologies are found not infrequently in various tarsal bones but are less commonly recognized in carpal bones. To assess the distribution of tarsal and carpal stress fractures. During the last three decades, the senior author collected locations of tarsal and carpal bone stress fracture callus seen on plain radiographs. 527 children with tarsal and carpal stress fractures were identified (88 children had multiple bones involved). The totals were: calcaneus 244, cuboid 188, talus 121, navicular 24, cuneiforms 23, capitate 18, lunate 1, and scaphoid 1. Stress fractures were more frequently seen once we became aware each particular bone could be involved. Tarsal and carpal stress fractures in children are not rare. Careful perusal of these bones is urged in all susceptible children with limping or wrist pain. (orig.)

  6. Stress fractures of ankle and wrist in childhood: nature and frequency

    Energy Technology Data Exchange (ETDEWEB)

    Oestreich, Alan E. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Bhojwani, Nicholas [University of Cincinnati College of Medicine, Cincinnati, OH (United States)

    2010-08-15

    Stress fractures of many etiologies are found not infrequently in various tarsal bones but are less commonly recognized in carpal bones. To assess the distribution of tarsal and carpal stress fractures. During the last three decades, the senior author collected locations of tarsal and carpal bone stress fracture callus seen on plain radiographs. 527 children with tarsal and carpal stress fractures were identified (88 children had multiple bones involved). The totals were: calcaneus 244, cuboid 188, talus 121, navicular 24, cuneiforms 23, capitate 18, lunate 1, and scaphoid 1. Stress fractures were more frequently seen once we became aware each particular bone could be involved. Tarsal and carpal stress fractures in children are not rare. Careful perusal of these bones is urged in all susceptible children with limping or wrist pain. (orig.)

  7. Endoplasmic reticulum stress in pathogenesis of diabetic retinopathy and effect of calcium dobesilate

    Institute of Scientific and Technical Information of China (English)

    Yu-Min Gui; Ming Zhao; Jie Ding

    2016-01-01

    Objective:To study the mechanism of endoplasmic reticulum stress in the pathogenesis of diabetic retinopathy and effect of calcium dobesilate.Methods:A total of 120 diabetic retinopathy patients treated in our hospital from January 2010 to September 2015 were enrolled in this article. The serum endoplasmic reticulum stress protein and interleukin protein expression levels were analyzed before and after calcium dobesilate treatment. A total of 55 cases of healthy subjects receiving physical examination in our hospital during the same period were taken as control group.Results:Serum endoplasmic reticulum stress proteins PERK, CHOP and IRE as well as interleukin proteins IL1, IL2, IL6 and IL10 expression significantly increased, serum MDA level significantly increased while SOD, CAT and GSHpx levels significantly decreased in diabetic retinopathy patients, and compared with control group (P<0.01); after calcium dobesilate treatment, above factors were significantly restored (P<0.01).Conclusions: Diabetic retinopathy is closely related to endoplasmic reticulum stress and calcium dobesilate treatment may improve diabetic retinopathy by inhibiting endoplasmic reticulum stress.

  8. Evaluation of Diversity and Traits Correlation in Spring Wheat Cultivars under Drought Stress

    Directory of Open Access Journals (Sweden)

    Mohammad Reza NAGHAVI

    2015-09-01

    Full Text Available In order to study of diversity and classify agro-morphological characters under normal irrigation and drought stress in spring wheat cultivars, 20 cultivars were evaluated in the research farm of University of Tabriz, Iran. According to the results, significant correlation was found between grain yield and number of spikes per plant, number of tiller per plant, number of fertile tillers, spike length, root length, root number, root volume, root diameter and root dry weight under both conditions. Moreover, 1,000 grain weight and plant dry weight had significant positive correlation with grain yield under drought stress. Factor analysis detected four and two factors which explained 96.77% and 90.59% of the total variation in normal irrigation and drought stress conditions, respectively. In drought stress condition the first factor justified 69.52% of total variation and was identified as yield factor. The second factor explained 21.07% of total variation and represented the biomass and plant height factor. Cluster analysis was based on the four and two factors obtained. According to the amount of factors for clusters obtained under drought stress, ‘Kavir’, ‘Niknejhad’, ‘Moghan 3’, ‘Darya’ and ‘Marvdasht’ were identified as the most drought tolerant cultivars. Other cluster was comprised of ‘Bahar’, ‘Pishtaz’, ‘Bam’, ‘Sepahan’, ‘Sistan’, ‘Pars’ and ‘Sivand’ and was named as the most sensitive under drought stress. Tolerant cultivars identified within the study can be used for direct culture or as genitors in breeding programs.

  9. Perceived sources of stress among Malaysian dental students.

    Science.gov (United States)

    Babar, Muneer G; Hasan, Syed S; Ooi, Yong J; Ahmed, Syed I; Wong, Pei S; Ahmad, Siti F; Mnm-Rosdy, Nik M; Malik, Normaliza A

    2015-05-02

    The study objectives were to identify the stress levels and to explore the impact of students' year of study and gender on the perceived sources of stress among Malaysian dental students. This was a cross-sectional study involving dental students from year one to year five from private and public universities in Malaysia. The study was formally approved by the Research and Ethics Committee, International Medical University Malaysia. Dental Environment Stress (DES) questionnaire was used for data collection and the gathered data were analyzed using SPSS® version 18. The Kruskal-Wallis and the Mann-Whitney U tests were used to compare stress items across various academic years and universities. A total of five hundred and twenty nine (529) students participated in this study. Fear of failing the course at the end of year exams (mean stress level=5.57); concerns regarding completion of clinical work (mean=5.30); and examination results and grades (mean=5.27) were found as top stressors among dental students. Female students had higher stress scores than males with respect to personal issues, academic performance, educational environment and learning of clinical skills. Students from public universities had higher stress scores than their counterparts from private universities. The Malaysian dental students reported higher levels of stress. Present study identified stressors affecting dental students' academic life, and highlights the importance of stress management programs and other measures to minimize the impact of stress on both academic and personal lives of the students.

  10. Synergistic effects of drought stress and photoperiods on phenology and secondary metabolism of Silybum marianum.

    Science.gov (United States)

    Zahir, Adnan; Abbasi, Bilal Haider; Adil, Muhammad; Anjum, Sumaira; Zia, Muhammad; Ihsan-Ul-Haq

    2014-09-01

    Silybum marianum is an important medicinal plant of the family Asteraceae, well known for its set of bioactive isomeric mixture of secondary metabolites "silymarin", primarily acting as a hepato-protective agent. Abiotic stress augments plant secondary metabolism in different plant tissues to withstand harsh environmental fluctuations. In the current study, our aim was to induce drought stress in vitro on S. marianum under the influence of different photoperiod treatments to study the effects, with respect to variations in secondary metabolic profile and plant growth and development. S. marianum was extremely vulnerable to different levels of mannitol-induced drought stress. Water deficiency inhibited root induction completely and retarded plant growth was observed; however, phytochemical analysis revealed enhanced accumulation of total phenolic content (TPC), total flavonoid content (TFC), and total protein content along with several antioxidative enzymes. Secondary metabolic content was positively regulated with increasing degree of drought stress. A dependent correlation of seed germination frequency at mild drought stress and antioxidative activities was established with 2 weeks dark + 2 weeks 16/8 h photoperiod treatment, respectively, whereas a positive correlation existed for TPC and TFC when 4 weeks 16/8 h photoperiod treatment was applied. The effects of drought stress are discussed in relation to phenology, seed germination frequency, biomass build up, antioxidative potential, and secondary metabolites accumulation.

  11. Depression, anxiety and stress in dental students.

    Science.gov (United States)

    Basudan, Sumaya; Binanzan, Najla; Alhassan, Aseel

    2017-05-24

    To measure the occurrence and levels of depression, anxiety and stress in undergraduate dental students using the Depression, Anxiety and Stress Scale (DASS-21). This cross-sectional study was conducted in November and December of 2014. A total of 289 dental students were invited to participate, and 277 responded, resulting in a response rate of 96%. The final sample included 247 participants. Eligible participants were surveyed via a self-reported questionnaire that included the validated DASS-21 scale as the assessment tool and questions about demographic characteristics and methods for managing stress. Abnormal levels of depression, anxiety and stress were identified in 55.9%, 66.8% and 54.7% of the study participants, respectively. A multiple linear regression analysis revealed multiple predictors: gender (for anxiety b=-3.589, p=.016 and stress b=-4.099, p=.008), satisfaction with faculty relationships (for depression b=-2.318, p=.007; anxiety b=-2.213, p=.004; and stress b=-2.854, prelationships (for depression b=-3.527, panxiety b=-2.213, p=.004; and stress b=-2.854, pstress b=-2.648, p=.045). The standardized coefficients demonstrated the relationship and strength of the predictors for each subscale. To cope with stress, students engaged in various activities such as reading, watching television and seeking emotional support from others. The high occurrence of depression, anxiety and stress among dental students highlights the importance of providing support programs and implementing preventive measures to help students, particularly those who are most susceptible to higher levels of these psychological conditions.

  12. Anticonvulsants to treat post-traumatic stress disorder.

    Science.gov (United States)

    Wang, Hee Ryung; Woo, Young Sup; Bahk, Won-Myong

    2014-09-01

    We reviewed the existing literature on the efficacy of anticonvulsants in treating post-traumatic stress disorder. We performed a literature search using PubMed, EMBASE and the Cochrane database on 30 September 2013. Randomized,controlled studies that investigated the efficacy of anticonvulsants for post-traumatic stress disorder were included in this review. Studies with retrospective designs, case reports and case series were excluded. A total of seven studies met the inclusion criteria for this review. Three studies used topiramate with negative findings regarding its efficacy. Two studies used divalproex, both of which failed to show superiority over placebo. One study used lamotrigine, with favourable results, and one study used tiagabine, with negative results. Future long-term studies with larger sample sizes are needed to investigate the clinical utility of anticonvulsants for posttraumatic stress disorder treatment.

  13. Response of porous beryllium to static and dynamic loading

    Energy Technology Data Exchange (ETDEWEB)

    Isbell, W.M.; Walton, O.R.; Ree, F.H.

    1977-07-01

    Previous investigstions of the mechanical response of porous materials to dynamic loading have been extended to include the shock wave response of a brittle metal. The complex response of berylliums of 85 to 90 percent porosity in two initial conditions has been examined in a theoretical and experimental program to be described. The study has resulted in the development of constitutive relations placed in hydrocodes which are capable of accurately predicting wave propagation in the berylliums. A comprehensive set of static (0 to 4 Gpa) and dynamic (0 to 35 Gpa) experiments was performed to measure the behavior of these brittle, porous materials to imposed loads. The results of the experiments guided a modeling effort which added several new features to previous models, including deviatoric stresses, porosity-dependent relaxation time of pore closure, elastic-plastic reopening of pores, and improved compaction functions.

  14. Response of porous beryllium to static and dynamic loading

    International Nuclear Information System (INIS)

    Isbell, W.M.; Walton, O.R.; Ree, F.H.

    1977-07-01

    Previous investigstions of the mechanical response of porous materials to dynamic loading have been extended to include the shock wave response of a brittle metal. The complex response of berylliums of 85 to 90 percent porosity in two initial conditions has been examined in a theoretical and experimental program to be described. The study has resulted in the development of constitutive relations placed in hydrocodes which are capable of accurately predicting wave propagation in the berylliums. A comprehensive set of static (0 to 4 Gpa) and dynamic (0 to 35 Gpa) experiments was performed to measure the behavior of these brittle, porous materials to imposed loads. The results of the experiments guided a modeling effort which added several new features to previous models, including deviatoric stresses, porosity-dependent relaxation time of pore closure, elastic-plastic reopening of pores, and improved compaction functions

  15. A theoretical argumentation on the consequences of moral stress.

    Science.gov (United States)

    Cronqvist, Agneta; Nyström, Maria

    2007-05-01

    Intensive care units are characterized by heavy workloads, increasing work complexity and ethical concerns related to life-and-death decisions. In the present study, it is assumed that there is a relationship between moral stress, support and competence for nurses in intensive care units. To analyse and describe the theoretical relationship between moral stress and support on the one hand and competence on the other, in the context of intensive care. A form of qualitative secondary analysis based on the findings from three original studies. In the analytic process a theory on professional competence was used. The findings suggest that imbalance due to moral stress between different competences hinders the development of collectively shared caring competence. Moral stress cannot be totally eliminated in the intensive care unit. But moral stress is not only a problem. It can also become a driving force to stimulate competence.

  16. Lymphocyte DNA damage and oxidative stress in patients with iron deficiency anemia.

    Science.gov (United States)

    Aslan, Mehmet; Horoz, Mehmet; Kocyigit, Abdurrahim; Ozgonül, Saadet; Celik, Hakim; Celik, Metin; Erel, Ozcan

    2006-10-10

    Oxidant stress has been shown to play an important role in the pathogenesis of iron deficiency anemia. The aim of this study was to investigate the association between lymphocyte DNA damage, total antioxidant capacity and the degree of anemia in patients with iron deficiency anemia. Twenty-two female with iron deficiency anemia and 22 healthy females were enrolled in the study. Peripheral DNA damage was assessed using alkaline comet assay and plasma total antioxidant capacity was determined using an automated measurement method. Lymphocyte DNA damage of patients with iron deficiency anemia was significantly higher than controls (ptotal antioxidant capacity was significantly lower (ptotal antioxidant capacity and hemoglobin levels (r=0.706, ptotal antioxidant capacity and hemoglobin levels were negatively correlated with DNA damage (r=-0.330, p<0.05 and r=-0.323, p<0.05, respectively). In conclusion, both oxidative stress and DNA damage are increased in IDA patients. Increased oxidative stress seems as an important factor that inducing DNA damage in those IDA patients. The relationships of oxidative stress and DNA damage with the severity of anemia suggest that both oxidative stress and DNA damage may, in part, have a role in the pathogenesis of IDA.

  17. Job stressors and job stress among teachers engaged in nursing activity.

    Science.gov (United States)

    Muto, Shigeki; Muto, Takashi; Seo, Akihiko; Yoshida, Tsutomu; Taoda, Kazushi; Watanabe, Misuzu

    2007-01-01

    Teachers and staff members engaged in nursing activity experience more stress than other workers. However, it is unknown whether teachers engaged in nursing activity in schools for handicapped children experience even greater stress. This study evaluated job stressors and job stress among such teachers using a cross-sectional study design. The subjects were all 1,461 teachers from all 19 prefectural schools for handicapped children in Shizuoka Prefecture, Japan. We used a brief job stress questionnaire for the survey and 831 teachers completed the questionnaire. Job stressors among teachers engaged in nursing activity were compared with those among teachers not engaged in nursing activity. Job stress among such teachers was estimated by the score for total health risk, and was compared with the score in the Japanese general population. Male and female teachers engaged in nursing activity had a significantly higher level of job stressors for physical work load and job control compared with those not engaged in nursing activity. The scores for total health risk among male and female teachers engaged in nursing activity were 102 points and 98 points, respectively. These scores were not markedly above 100 points which is the mean score in the Japanese general population.

  18. Insulin resistance in H pylori infection and its association with oxidative stress.

    Science.gov (United States)

    Aslan, Mehmet; Horoz, Mehmet; Nazligul, Yasar; Bolukbas, Cengiz; Bolukbas, F Fusun; Selek, Sahbettin; Celik, Hakim; Erel, Ozcan

    2006-11-14

    To determine the insulin resistance (IR) and oxidative status in H pylori infection and to find out if there is any relationship between these parameters and insulin resistance. Fifty-five H pylori positive and 48 H pylori negative patients were enrolled. The homeostasis model assessment (HOMA) was used to assess insulin resistance. Serum total antioxidant capacity (TAC), total oxidant status (TOS) and oxidative stress index (OSI) were determined in all subjects. The total antioxidant capacity was significantly lower in H pylori positive group than in H pylori negative group (1.36 +/- 0.33 and 1.70 +/- 0.50, respectively; P total oxidant status and oxidative stress index were significantly higher in H pylori positive group than in H pylori negative group (6.79 +/- 3.40 and 5.08 +/- 0.95, and 5.42 +/- 3.40 and 3.10 +/- 0.92, respectively; P total antioxidant capacity (r = -0.251, P total oxidant status (r = 0.365, P antioxidant vitamins to H pylori eradication therapy on insulin resistance during H pylori infection.

  19. Stress and radioresistance (genetic aspects)

    International Nuclear Information System (INIS)

    Lyubaschevsky, N.M.; Grigorkina, E.B.

    1995-01-01

    Inbred mice and randomly bred stock were exposed to long-term adrenaline and hypothermia stress effects for unification of their functional status, followed by acute total gamma irradiation by equal-effect doses (LD 50/30 ). The significant reduction of lethality distribution in inbred mice after combined stress and radiation effects was observed. The spread of lethality in random bred stock was increased as compared to the control group. The post-irradiation mortality in experimental animals differed only slightly from the values in the control groups. Conclusions are drawn about the principal meaning of genotype in radiosensitivity, about the role of an organism's functional status in determination of death date and about the possible epigenetic structuralisation of linear mice by radioresistance. (Author)

  20. Occupational Stress in Dental Practice amongst Government ...

    African Journals Online (AJOL)

    Objectives: The aim of this study is to compare the level of occupational stress amongst government-employed and private dental practitioners in eastern Nigeria. Materials and methods: A total of 62 questionnaires were randomly distributed among government-employed and private practicing dental surgeons with five ...

  1. Stress-dependent coordination of transcriptome and translatome in yeast.

    Directory of Open Access Journals (Sweden)

    Regula E Halbeisen

    2009-05-01

    Full Text Available Cells rapidly alter gene expression in response to environmental stimuli such as nutrients, hormones, and drugs. During the imposed "remodeling" of gene expression, changes in the levels of particular mRNAs do not necessarily correlate with those of the encoded proteins, which could in part rely on the differential recruitment of mRNAs to translating ribosomes. To systematically address this issue, we have established an approach to rapidly access the translational status of each mRNA in the yeast Saccharomyces cerevisiae by affinity purification of endogenously formed ribosomes and the analysis of associated mRNAs with DNA microarrays. Using this method, we compared changes in total mRNA levels (transcriptome with ribosome associations (translatome after the application of different conditions of cellular stress. Severe stresses, induced by amino acid depletion or osmotic shock, stimulated highly correlated responses affecting about 15% of both total RNA levels and translatome. Many of the regulated messages code for functionally related proteins, thus reflecting logical responses to the particular stress. In contrast, mild stress provoked by addition of Calcofluor-white and menadione altered the translatome of approximately 1% of messages with only marginal effects on total mRNA, suggesting largely uncorrelated responses of transcriptome and translatome. Among these putative translationally regulated messages were most components of the mitochondrial ATPase. Increased polysome associations of corresponding messages and higher mitochondrial ATPase activities upon treatment confirmed the relevance for regulation of this macromolecular complex. Our results suggest the presence of highly sensitive translational regulatory networks that coordinate functionally related messages. These networks are preferentially activated for rapid adaptation of cells to minor environmental perturbations.

  2. Stress Management: Job Stress

    Science.gov (United States)

    Healthy Lifestyle Stress management Job stress can be all-consuming — but it doesn't have to be. Address your triggers, keep perspective and ... stress triggers, it's often helpful to improve time management skills — especially if you tend to feel overwhelmed ...

  3. Developing SyrinOX total antioxidant capacity assay for measuring antioxidants in humans.

    Science.gov (United States)

    Prasetyo, Endry N; Knes, Otto; Nyanhongo, Gibson S; Guebitz, Georg M

    2013-02-01

    Accurate monitoring of the antioxidant status or of oxidative stress in patients is still a big challenge in clinical laboratories. This study investigates the possibility of applying a newly developed total antioxidant capacity assay method based on laccase or peroxidase oxidized syringaldazine [Tetramethoxy azobismethylene quinone (TMAMQ)] which is referred to here as SyrinOX, as a diagnostic tool for monitoring both oxidative stress and antioxidant status in patients. Attempts to adapt the Randox total antioxidant procedure [simultaneous incubation of the radical generating system (metmyoglobin and H(2) O(2) ) and antioxidant sample] for SyrinOX were abandoned after it was discovered that the H(2) O(2) reacted with enzymatically generated TMAMQ and ABTS radicals at a rate of 6.4 × 10(-2) /μM/s and 5.7 × 10(-3) /μM/s respectively. Thus this study for the first time demonstrates the negative effects of H(2) O(2) in the Randox system. This leads to erroneous results because the total antioxidant values obtained are the sum of radicals reduced by antioxidants plus those reacting with the radical generating system. Therefore they should be avoided not only for this particular method but also when using other similar methods. Consequently, SyrinOX is best applied using a three-step approach involving, production of TMAMQ, recovery and purification (free from enzyme and other impurities) and then using TMAMQ for measuring the total antioxidant capacity of samples. Using this approach, the reaction conditions for application of SyrinOX when measuring the total antioxidant capacity of plasma sample were determined to be 50% (v/v) ethanol/50 mM sodium succinate buffer pH 5.5, between 20 and 25 °C for at least 1 h. © 2012 The Authors. International Journal of Experimental Pathology © 2012 International Journal of Experimental Pathology.

  4. Determinants of Perceived Stress in Individuals with Obesity: Exploring the Relationship of Potentially Obesity-Related Factors and Perceived Stress.

    Science.gov (United States)

    Junne, Florian; Ziser, Katrin; Giel, Katrin Elisabeth; Schag, Kathrin; Skoda, Eva; Mack, Isabelle; Niess, Andreas; Zipfel, Stephan; Teufel, Martin

    2017-01-01

    Associations of specific types of stress with increased food intake and subsequent weight gain have been demonstrated in animal models as well as in experimental and epidemiological studies on humans. This study explores the research question of to what extent potentially obesity-related factors determine perceived stress in individuals with obesity. N = 547 individuals with obesity participated in a cross-sectional study assessing perceived stress as the outcome variable and potential determinants of stress related to obesity. Based on the available evidence, a five factorial model of 'obesity-related obesogenic stressors' was hypothesized, including the dimensions, 'drive for thinness', 'impulse regulation', 'ineffectiveness', 'social insecurity', and 'body dissatisfaction'. The model was tested using multiple linear regression analyses. The five factorial model of 'potentially obesity-related stressors' resulted in a total variance explanation of adjusted R² = 0.616 for males and adjusted R² = 0.595 for females for perceived stress. The relative variance contribution of the five included factors differed substantially for the two sexes. The findings of this cross-sectional study support the hypothesized, potentially obesity-related factors: 'drive for thinness', 'impulse regulation', 'ineffectiveness', 'social insecurity', and 'body dissatisfaction' as relevant determinants of perceived stress in individuals with obesity. © 2017 The Author(s) Published by S. Karger GmbH, Freiburg.

  5. Systemic oxidative stress markers in animal model for depression

    DEFF Research Database (Denmark)

    Bouzinova, Elena; Kravtsova, Violetta; Aalkjær, Christian

    Involvement of oxidative stress (OxS) in development of major depressive disorder has recently become evident, though mechanisms behind this remain elusive. We analyzed therefore OxS pathways in rat Chronic Mild Stress (CMS) model of depression. Rats are exposed to chronic unpredictable mild...... mg/kg/day). Saline injections were done to control the vehicle effect. Escitalopram treated rats were sub-divided into 2 groups: responders and non-responders, according to their hedonic state and compared to non-stressed rats, treated with either saline or Escitalopram. Measurement of total...... glutathione and malondialdehyde (MDA) in lungs, heart, skeletal muscles, liver, saphenous, mesenteric, and tail arteries were used as estimates for OxS. In heart, glutathione was increased in CMS rats in comparison with non-stressed vehicle group. Accordingly, an estimate for free radical activity, MDA...

  6. Effect of Alkaline Stress on Some Morphophysiologic Characteristics of Two Varieties of Safflower (Carthamus tinctorius L.

    Directory of Open Access Journals (Sweden)

    Sh Bemany Golnabadi

    2016-12-01

    , shoot and root dry weight, Fv/Fm, PI, proline, total carbohydrate, malondialdehyde content, cha, chb, total chlorophyll, cartonoied content, potassium, sodium content and sodium to potassium rate were measured. Results and Discussion Result showed that with increasing alkaline stress, decreased shoot and root height, shoot and root dry weight. A similar result had observed previously in sugar beet. Researches have indicated that plants respond to elevated NaHCO3 concentrations in soil or in growing medium solution with decreased shoot and root growth. This could be due to either HCO3− or Na+. Many of the data test showed high pH as a key factor in limiting plant growth and development under alkaline conditions. 411 variety showed superiority compared to Sofeh cultivar in mentioned characteristics. Also, Fv/Fm and PI decreased under alkaline stress condition, whereas proline, total carbohydrate and malondialdehyde content increased. Also, the increases in proline and total carbohydrate content were reported in wheat under alkaline stress condition. Baghre and Roosta (2012 reported that Fv/Fm values and PI reduced under alkalinity stress. In the present experiment, alkaline stress decreased cha, chb and total chlorophyll whereas it increased cartonoied content. Yang et al., (2009a concluded that in alkalinity stress, the contents of Chl and Car in the barley plants decreased sharply with increased stress in comparison to salinity stress. They also stated that high pH might decrease contents of photosynthetic pigments. Potassium content decreased under alkaline stress condition whereas sodium and sodium to potassium rate increased. Also, Zhang and Chun-Sheng (2009 reported that with increasing alkaline stress, potassium content decreased in Lathyrus quinquenervius whereas, sodium content and sodium to potassium rate increase. In wheat stems, a decrease in potassium content and potassium to sodium rate and an increase in sodium content were also observed. A high

  7. A Cascade Disaster Caused by Geological and Coupled Hydro-Mechanical Factors—Water Inrush Mechanism from Karst Collapse Column under Confining Pressure

    Directory of Open Access Journals (Sweden)

    Hao Li

    2017-11-01

    Full Text Available The water inrush from karst collapse column (KCC is a cascading, vicious cycle disaster caused by geological and mining activities, that can cause serious casualties and property losses. The key to preventing this risk is to study the mechanism of water inrush under confining pressure. Aiming at the investigationg the characteristics of the KCC named X1 in Chensilou mine, a series of methods, including connectivity experiments, water pressure monitoring tests in two side-walls, and numerical simulations based on plastic damage-seepage (PD-S theory have been developed. The methods are used to test the security of the 2519 mining area, the damage thickness, pore water pressure, and seepage vector in the X1. The results indicate that the X1 has a certain water blocking capacity. In addition, with the decrease of confining pressure and increase of shear stress, deviatoric stress could cause the increase of permeability, the reduction of strength, and the reduction of pore water pressure in KCC. Therefore the increased effective stress in the rock will force the rock to become more fractured. Conversely, the broken rock could cause the change of stress, and further initiate new plastic strains, damage and pore water pressure until a new equilibrium is reached. This cascading water inrush mechanism will contribute to the exploitation of deep coal resources in complex geological and hydrogeological conditions.

  8. Effect of tensile stress on the 3D reversible and irreversible differential magnetic susceptibilities

    International Nuclear Information System (INIS)

    Mao, Weihua; Atherton, David L.

    2001-01-01

    Magnetic hysteresis loops in three orthogonal directions are measured for a line pipe steel sample while the external magnetic field is applied in a direction perpendicular to the tensile stress direction. The total magnetization vector is calculated. This tends to the stress direction when tensile stress is applied. The reversible and irreversible differential magnetic susceptibilities are derived. It is found that the susceptibilities in all three directions are enhanced with increasing tensile stress, although the increase in the stress direction is much larger than in the other directions. [copyright] 2001 American Institute of Physics

  9. Comparative inter-institutional study of stress among dentists.

    Science.gov (United States)

    Pozos-Radillo, Blanca E; Galván-Ramírez, Ma Luz; Pando, Manuel; Carrión, Ma De los Angeles; González, Guillermo J

    2010-01-01

    Dentistry is considered to be a stressful profession due to different factors caused by work, representing a threat to dentists'health. The objectives of this work were to identify and compare chronic stress in dentists among the different health institutions and the association of stress with risk factors. The study in question is observational, transversal and comparative; 256 dentists were included, distributed among five public health institutions in the city of Guadalajara, Jalisco, Mexico, namely: the Mexican Institute of Social Security (IMSS), the Ministry of Health (SS), the Integral Development of the Family (DIF), the Social Security Services Institute for the Workers (ISSSTE) and the University of Guadalajara (U. de G) Data were obtained by means of the census technique. Stress was identified using the Stress Symptoms Inventory and the statistical analysis was performed using the Odds Ratio (O.R.) and the chi-square statistic. From the total population studied, 219 subjects presented high levels of chronic stress and 37, low levels. In the results of comparative analysis, significant differences were found between IMSS and U. de G and likewise between IMSS and SS. However, in the analysis of association, only U. de G was found to be associated with the high level of chronic stress.

  10. The role of stress in IBS symptom severity

    Directory of Open Access Journals (Sweden)

    Sanda Pletikosic

    2016-04-01

    Full Text Available Irritable bowel syndrome is regarded as a biopsychosocial disorder, the result of a complex combination of predisposing, precipitating and perpetuating factors. Personality traits, affective status and stress are some of the relevant factors contributing to lower quality of life and symptom exacerbation in IBS patients. In order to examine the role of stress in IBS symptom exacerbation, the aims of this study were to explore the relationship of daily stressful events and symptom severity in a prospective manner and to explore the roles of neuroticism, anxiety, depression and stress in the vicious circle of symptom perpetuation. A total of 49 patients with IBS reported their symptom severity and daily stressful events intensity each day for 14 consecutive days. They also completed the Big five personality inventory, the Beck Depression Inventory and the State-trait anxiety inventory. Cross-correlation analyses were performed on the time series data for daily stress and symptom severity for each participant separately. Four different patterns of relationships were found in different subgroups of participants: positive cross-correlations of symptom severity and stress intensity on the same day; higher symptom severity on days following stressful days; lower symptom severity on days following stressful days; and lower stress intensity on days following severe symptoms. Using average scores for daily stress and symptom severity, as well as scores for neuroticism, anxiety and depression, we performed a path analysis to test a model of symptom exacerbation. It showed that, on the group level, average stress intensity predicts average symptom severity. Neuroticism and anxiety were not significant predictors of symptom severity, while depression showed a marginally significant relationship with symptom severity, mediated by stress intensity. In conclusion, depression and daily stress seem to be important contributors to the vicious circle of IBS symptom

  11. Web-Based and Mobile Stress Management Intervention for Employees: A Randomized Controlled Trial

    OpenAIRE

    Heber, Elena; Lehr, Dirk; Ebert, David Daniel; Berking, Matthias; Riper, Heleen

    2016-01-01

    Background: Work-related stress is highly prevalent among employees and is associated with adverse mental health consequences. Web-based interventions offer the opportunity to deliver effective solutions on a large scale; however, the evidence is limited and the results conflicting. Objective: This randomized controlled trial evaluated the efficacy of guided Web-and mobile-based stress management training for employees. Methods: A total of 264 employees with elevated symptoms of stress (Perce...

  12. Total antioxidants in plasma of hemodialysed patients and healthy controls measured by two commercial assays

    OpenAIRE

    Ruskovska, Tatjana; Jansen, Eugene

    2012-01-01

    Introduction: As a result of an increased interest in oxidative stress research, in both basic and clinical studies, numerous commercial test kits became available. The aim of this study was to evaluate the results for total antioxidants measured by two commercial assays in a complex clinical condition such as single hemodialysis session in patients on chronic hemodialysis treatment, in comparison to healthy controls. Methods: The level of plasma total antioxidants was measured by BAP ...

  13. Female urogenital dysfunction following total mesorectal excision for rectal cancer

    Directory of Open Access Journals (Sweden)

    Raja Ashraf

    2006-01-01

    Full Text Available Abstract Background The effect of Total Mesorectal Excision (TME on sexual function in the male is well documented. However, there is little literature in female patients. The aim of this study was to review the pelvic autonomic nervous anatomy in the female and to perform a retrospective audit of urinary and sexual function in women following surgery for rectal cancer where TME had been performed. Urogenital dysfunction was assessed through interview and questionnaire. Method Twenty-three questionnaires, eighteen returned, were sent to women with a mean age 65.5 yrs (range 34–86. All had undergone total mesorectal excision for rectal cancer between 1998–2001. Mean follow-up was 18.8 months (range 3–35. Results Preoperatively 5/18 (28% were sexually active, 3/18 (17% of patients described urinary frequency and nocturia and 7/18 (39% described symptoms of stress incontinence prior to surgery. Postoperatively all sexually active patients remained active although all described some discomfort with penetration. Two of the patients sexually active described reduced libido secondary to the stoma. Postoperative urinary symptoms developed with 59% reporting the development of nocturia, 18% developed stress incontinence and one patient required a permanent catheter. Of those with symptoms, 80% persisted longer than three months from surgery. Symptoms were predominant in those patients with low rectal cancers, particularly those undergoing abdomino-perineal excision and in those who had previously undergone abdominal hysterectomy. Conclusion The treatment of rectal cancer involves surgery to the pelvic floor. Despite nerve preservation this is associated with the development of worsening nocturia and stress incontinence. This is most marked in those patients who had previously undergone a hysterectomy. Further studies are warranted to assess the interaction with previous gynaecological surgery.

  14. Interactive effects of dietary restraint and adiposity on stress-induced eating and the food choice of children.

    Science.gov (United States)

    Roemmich, James N; Lambiase, Maya J; Lobarinas, Christina L; Balantekin, Katherine N

    2011-12-01

    The Individual Differences Model posits that individual differences in physiological and psychological factors explain eating behaviors in response to stress. The purpose was to determine the effects of individual differences in adiposity, dietary restraint and stress reactivity on children's energy intake and food choices. A total of 40 boys and girls, age 8-12 years, with wide ranges of dietary restraint, adiposity, and stress reactivity were measured for total energy intake and choice of energy dense 'comfort' and lower density 'healthy' foods following reading and speech stressor manipulations. When exploring the interaction of dietary restraint and stress reactivity, lower restraint/lower reactivity and lower restraint/higher reactivity were associated with reductions in energy intake (37-62 kcal) and comfort food (33-89 kcal). Higher restraint/lower reactivity was associated with consuming 86 fewer total kcal and 45 fewer kcal of comfort food. Only higher restraint/higher reactivity predicted increased energy intake (104 kcal) and comfort food (131 kcal). The interaction of dietary restraint and percentage body fat revealed that lower restraint/lower adiposity was associated with consuming 123 fewer kcal after being stressed with the entire reduction due to a decrease in comfort food. Lower restraint/higher adiposity was associated with consuming 116 kcal more after being stressed with 70% (81 kcal) of the increase in the form of comfort foods. Higher restraint/lower adiposity and higher restraint/higher adiposity were associated with smaller changes in total energy intake of 22 kcal and 1 kcal; respectively. Both restraint and adiposity moderated the effect of stress on energy intake and food choice. Children with greater adiposity may be at risk for stress-induced eating to contribute to their obesity. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. Effects of Meridian Acupressure Massage on Body Composition, Edema, Stress, and Fatigue in Postpartum Women.

    Science.gov (United States)

    Jung, Geum-Sook; Choi, In-Ryoung; Kang, Hee-Young; Choi, Eun-Young

    2017-10-01

    This study aims to investigate the effects of meridian acupressure massage on body composition, edema, stress, and fatigue in postpartum women. A quasi-experimental design with a nonequivalent control group was utilized. The Postpartum Care Center of Women's Hospital in Gwangju City, Republic of Korea. The study group consisted of 39 postpartum women, 19 in the experimental group and 20 in the control group, recruited from the postpartum care center of Women's Hospital in Gwangju city, South Korea. The experimental group was provided with meridian acupressure massage for 90 min daily over 5 days as an experimental therapy. Body composition (body weight, BMI, total body water, ECW ratio, LBM, and body fat) Edema (subjective edema, average girth of the upper limbs, and average girth of the lower limbs), Stress (psychological stress and physical stress), and Fatigue. The experimental group demonstrated a significantly larger decrease compared with the control group in measures of body composition, edema, total subjective stress, psychological stress, and subjective fatigue. Meridian acupressure massage can hasten the return to original body composition after childbirth.

  16. The Malay Version of the Perceived Stress Scale (PSS)-10 is a Reliable and Valid Measure for Stress among Nurses in Malaysia.

    Science.gov (United States)

    Sandhu, Sukhvinder Singh; Ismail, Noor Hassim; Rampal, Krishna Gopal

    2015-11-01

    The Perceived Stress Scale-10 (PSS-10) is widely used to assess stress perception. The aim of this study was to translate the original PSS-10 into Malay and assess the reliability and validity of the Malay version among nurses. The Malay version of the PSS-10 was distributed among 229 nurses from four government hospitals in Selangor State. Test-retest reliability and concurrent validity was conducted with 25 nurses with the Malay version of the Depression Anxiety Stress Scales (DASS) 21. Cronbach's alpha, confirmatory factor analysis (CFA), intraclass correlation coefficient and Pearson's r correlation coefficient were used to determine the psychometric properties of the Malay PSS-10. Two factor components were yielded through exploratory factor analysis with eigenvalues of 3.37 and 2.10, respectively. Both of the factors accounted for 54.6% of the variance. CFA yielded a two-factor structure with satisfactory goodness-of-fit indices [x 2 /df = 2.43; comparative fit index (CFI) = 0.92, goodness-of-fit Index (GFI) = 0.94; standardised root mean square residual (SRMR) = 0.07 and root mean square error of approximation (RMSEA) = 0.08 (90% CI = 0.07-0.09)]. The Cronbach's alpha coefficient for the total items was 0.63 (0.82 for factor 1 and 0.72 for factor 2). The intraclass correlation coefficient (ICC) was 0.81 (95% CI: 0.62-0.91) for test-retest reliability testing after seven days. The total score and the negative component of the PSS-10 correlated significantly with the stress component of the DASS-21: (r = 0.61, P < 0.001) and (r = 0.56, P < 0.004), respectively. The Malay version of the PSS-10 demonstrated a satisfactory level of validity and reliability to assess stress perception. Therefore, this questionnaire is valid in assessing stress perception among nurses in Malaysia.

  17. Stress shadows - a controversial topic

    Science.gov (United States)

    Lasocki, Stanislaw; Karakostas, Vassilis G.; Papadimitriou, Eletheria E.; Orlecka-Sikora, Beata

    2010-05-01

    the sign of the change though distinctly more in areas of positive than of negative change. In the case of seismicity accompanying underground mining exploitation the coseismic stress changes expressed in terms of the Coulomb failure function are at least of one order smaller than those for earthquakes. Furthermore, they are only a small component of the total stress field variations in mining rockmass, which are mainly controlled by the mining process. Nevertheless, our studies of the induced seismicity in the Rudna mine in the Legnica-Głogow Copper District in Poland showed that the influence of the Coulomb stress changes on locations of subsequent events was statistically significant. We analyzed series of seismic events quantifying the triggering and inhibiting effect by the proportion of events in the series whose locations were consistent with the stress increased and stress decreased zones, respectively. It was found out that more than 60 per-cent of the analyzed seismic events occurred in areas where stress was enhanced due to the occurrence of previous events. The significance of this result was determined by comparing it with 2000 results of the same analysis carried out on the random permutations of the original series of events. The test indicated that the locations in positive stress changes areas were preferred statistically significantly when the stress changes exceeded 0.05 bar. However, no statistically significant inhibiting effect of negative static stress changes, within the considered range of these changes, was ascertained. Here we present details of these two studies and discuss possible reasons behind the negative conclusions on the existence of stress shadows.

  18. Modelling Dynamic Behaviour and Spall Failure of Aluminium Alloy AA7010

    Science.gov (United States)

    Ma'at, N.; Nor, M. K. Mohd; Ismail, A. E.; Kamarudin, K. A.; Jamian, S.; Ibrahim, M. N.; Awang, M. K.

    2017-10-01

    A finite strain constitutive model to predict the dynamic deformation behaviour of Aluminium Alloy 7010 including shockwaves and spall failure is developed in this work. The important feature of this newly hyperelastic-plastic constitutive formulation is a new Mandel stress tensor formulated using new generalized orthotropic pressure. This tensor is combined with a shock equation of state (EOS) and Grady spall failure. The Hill’s yield criterion is adopted to characterize plastic orthotropy by means of the evolving structural tensors that is defined in the isoclinic configuration. This material model was developed and integration into elastic and plastic parts. The elastic anisotropy is taken into account through the newly stress tensor decomposition of a generalized orthotropic pressure. Plastic anisotropy is considered through yield surface and an isotropic hardening defined in a unique alignment of deviatoric plane within the stress space. To test its ability to describe shockwave propagation and spall failure, the new material model was implemented into the LLNL-DYNA3D code of UTHM’s. The capability of this newly constitutive model were compared against published experimental data of Plate Impact Test at 234m/s, 450m/s and 895m/s impact velocities. A good agreement is obtained between experimental and simulation in each test.

  19. Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination.

    Science.gov (United States)

    Melillo, Paolo; Bracale, Marcello; Pecchia, Leandro

    2011-11-07

    This study investigates the variations of Heart Rate Variability (HRV) due to a real-life stressor and proposes a classifier based on nonlinear features of HRV for automatic stress detection. 42 students volunteered to participate to the study about HRV and stress. For each student, two recordings were performed: one during an on-going university examination, assumed as a real-life stressor, and one after holidays. Nonlinear analysis of HRV was performed by using Poincaré Plot, Approximate Entropy, Correlation dimension, Detrended Fluctuation Analysis, Recurrence Plot. For statistical comparison, we adopted the Wilcoxon Signed Rank test and for development of a classifier we adopted the Linear Discriminant Analysis (LDA). Almost all HRV features measuring heart rate complexity were significantly decreased in the stress session. LDA generated a simple classifier based on the two Poincaré Plot parameters and Approximate Entropy, which enables stress detection with a total classification accuracy, a sensitivity and a specificity rate of 90%, 86%, and 95% respectively. The results of the current study suggest that nonlinear HRV analysis using short term ECG recording could be effective in automatically detecting real-life stress condition, such as a university examination.

  20. Synthesis of stress proteins in winter wheat seedlings under gamma-radiation

    International Nuclear Information System (INIS)

    Gudkova, N.V.; Kosakovskaya, I.V.; Major, P.S.

    2001-01-01

    A universal cellular response to a number of diverse stresses is the synthesis of a set of stress proteins. Most of them are heat shock proteins (HSP). We show that both heat shock and gamma-radiation enhance the synthesis of HSP70 in the total protein fractions of winter wheat seedlings. It is found that a dose of 15 Gy induced the synthesis of 35 and 45 kD proteins after 5 h of irradiation in both total and mitochondrial protein fractions. On the second day after exposure, both 35 and 45 kD proteins were not observed, but new total proteins with a molecular weight of 90 and 92 kD appeared. The synthesis of 35 and 45 kD proteins after gamma-irradiation is revealed for the first time, their function being now unknown

  1. Measurement techniques for in situ stresses around underground constructions in a deep clay formation

    Directory of Open Access Journals (Sweden)

    Li X.L.

    2010-06-01

    Full Text Available Disposal in deep underground geological formations is internationally recognized as the most viable option for the long-term management of high-level radioactive waste. In Belgium, the Boom clay formation is extensively studied in this context, in particular at the 225 m deep HADES Underground Research Facility in Mol. A cost-effective design of deep underground structures requires an accurate assessment of the in situ stresses; a good estimation of these stresses is also essential when interpreting in situ experiments regarding the hydro-mechanical behaviour of the host formation. Different measurement techniques are available to provide data on the stress evolution and other mechanical properties of the geological formation. The measurement can be direct (measurement of total pressure, or it can be an indirect technique, deriving the stress from related quantities such as strain (changes in structural members. Most total stress measurements are performed through permanently installed sensors; also once-only measurements are performed through specific methods (e.g. pressuremeter. Direct measurement of the stress state is challenging due to the complex mechanical behaviour of the clay, and the fact that the sensor installation inevitably disturbs the original stress field. This paper describes ways to deal with these problems and presents the results obtained using different techniques at HADES.

  2. Lower urinary tract symptoms after total and subtotal hysterectomy

    DEFF Research Database (Denmark)

    Gimbel, Helga; Zobbe, Vibeke; Andersen, Birthe Jakobsen

    2005-01-01

    The aim of this Danish multicenter trial was to compare the proportion of women with lower urinary tract symptoms after total abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (SAH) for benign uterine disorders. A total of 319 women were randomized to TAH (n = 158) or SAH (n = 161......). Women were followed up for 1 year by strict data collection procedures, including postal questionnaires. Results were analyzed by intention-to-treat analyses. Urinary incontinence was found less often among TAH women than among SAH women. This was due to a larger reduction of the number of women...... with stress and urinary incontinence in the TAH group. No other differences were found between the two operation methods. The number of women with urinary incontinence and frequency was reduced from study entry for follow-up, while double/triple voiding was increased. Incontinent women had significantly lower...

  3. Association between oxidative stress index and serum lipid levels in healthy young adults

    International Nuclear Information System (INIS)

    Turkdogan, K.E.

    2014-01-01

    Objectives: To investigate the relationship between lipid levels and oxidative stress index in healthy young adults. Methods: The study was camed out at the Department of Emergency Service, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey, between January 2011 and July 2012. A total of 100 healthy adult volunteers were enrolled in the study. Venous blood samples (10 ml) were collected from all individuals, and serum lipid parameters, total antioxidant capacity and total oxidative levels were studied. SPSS 15 was used for statistical analysis. Results: Overall, there were 84 (84%) males and 16 (16%) females. The mean age of the male population was 30+-3 years, while that of the females was 31+-3 years. Overall age ranged from 25 to 35 years. A statistically significant correlation was found between the oxidative stress index and serum cholesterol (p<0.001; r=0.596), triglyceride (p<0.001; r=0.476) and low-density lipoprotein levels (p<0.001; r=0.318). However, no significant correlation was found between oxidative stress index and serum high-density lipoprotein levels (p=0.564; r=0.058). Conclusion: The results showed that even at an early age, there is a direct linear correlation between oxidative stress and serum lipid levels. (author)

  4. Psychological stress during pregnancy and stillbirth: prospective study

    DEFF Research Database (Denmark)

    Wisborg, K.; Barklin, A.; Hedegaard, M.

    2008-01-01

    habits, alcohol and caffeine intake during pregnancy, education and cohabitation failed to change the result. The results remained essentially unchanged after exclusion of preterm deliveries. Exclusion of women with complications during pregnancy such as diabetes, hypertension, vaginal bleeding......OBJECTIVE: To study the association between psychological stress during pregnancy and stillbirth. DESIGN: Prospective follow-up study. SETTING: Aarhus University Hospital, Skejby, Denmark,1989-98. POPULATION: A total of 19 282 singleton pregnancies in women with valid information about...... psychological stress during pregnancy. METHODS: Information about psychological stress during pregnancy was obtained from questionnaires and measured by the 12-item General Health Questionnaires (GHQ). A score was generated by the sum of all the answers, each contributing a value between 0 (low psychological...

  5. Assessment of oxidative stress markers in recurrent pregnancy loss: a prospective study.

    Science.gov (United States)

    Yiyenoğlu, Özgür Bilgin; Uğur, Mete Gürol; Özcan, Hüseyin Çağlayan; Can, Günay; Öztürk, Ebru; Balat, Özcan; Erel, Özcan

    2014-06-01

    To determine the levels of oxidative stress markers in recurrent pregnancy loss using a novel automated method. 30 pregnant women in their first trimester with a history of recurrent pregnancy loss (RPL) and 30 healthy pregnant women were enrolled in this prospective controlled study. Total antioxidant capacity (TAC), total oxidant level (TOL) and oxidative stress index (OSI) in maternal serum were measured using the more recently designated Erel method. We observed statistically significant increased TOL and OSI levels in patient group (p = 0.032, p = 0.007, respectively). We also demonstrated statistically significant decreased TAC in pregnant women who had a history of RPL (p = 0.013). Our results support the concept that oxidative stress plays a central role in the etiopathogenesis of RPL. Further studies to evaluate the predictive role of TAC, TOL, OSI levels using Erel method are needed.

  6. Heat stress intervention research in construction: gaps and recommendations.

    Science.gov (United States)

    Yang, Yang; Chan, Albert Ping-Chuen

    2017-06-08

    Developing heat stress interventions for construction workers has received mounting concerns in recent years. However, limited efforts have been exerted to elaborate the rationale, methodology, and practicality of heat stress intervention in the construction industry. This study aims to review previous heat stress intervention research in construction, to identify the major research gaps in methodological issues, and to offer detailed recommendations for future studies. A total of 35 peer-reviewed journal papers have been identified to develop administrative, environmental or personal engineering interventions to safeguard construction workers. It was found that methodological limitations, such as arbitrary sampling methods and unreliable instruments, could be the major obstacle in undertaking heat stress intervention research. To bridge the identified research gaps, this study then refined a research framework for conducting heat stress intervention studies in the construction industry. The proposed research strategy provides researchers and practitioners with fresh insights into expanding multidisciplinary research areas and solving practical problems in the management of heat stress. The proposed research framework may foster the development of heat stress intervention research in construction, which further aids researchers, practitioners, and policymakers in formulating proper intervention strategies.

  7. Taking aim at nurse stress: a call to action.

    Science.gov (United States)

    Kashani, Mariam; Eliasson, Arn; Chrosniak, Linda; Vernalis, Marina

    2010-02-01

    The study investigates stress levels and related behaviors of nurses in a military medical center during wartime. In 2007, nurses completed a questionnaire survey with objective validation of data in a subsample using actigraphy over 12 weeks. Of 270 nurses, 255 (94%) returned surveys. A total of 81% reported moderately high or high stress with sources listed as work (66%) and fatigue (39%). Many reported coming to work despite feeling ill and/or stressed (13.6 days/3 months). In contrast, morale was high or moderately high in 71%. Nurses reported an average of 5.5 hours of sleep/night, 8.8 h/wk taken for self, and 3.8 h/wk for exercise. Actigraphy data showed an average of 6.0 hours of sleep/night. These findings highlight a mismatch between stress levels and coping perceptions indicating an inability to properly care for self. To manage the effects of chronic stress, nurse leaders should implement systems targeting healthy life balance.

  8. The Effect of Stress Management on Occupational Stress and Satisfaction among Midwives in Obstetrics and Gynecology Hospital Wards in Iran.

    Science.gov (United States)

    Karimyar Jahromi, Mahdi; Minaei, Shahnaz; Abdollahifard, Sareh; Maddahfar, Majid

    2016-09-01

    Occupational stress is one of the major problems of health care staff, substantially affecting their professional and personal performance. This research has been conducted with the aim of determining the effect of stress management on occupational stress and satisfaction among the Midwives in Obstetrics and Gynecology Hospital wards at Motahari Hospital in Jahrom, Iran 2013-2014. This is a Quasi-experimental study of the pre- and post-clinical trials type. The study population included midwives employed in the Obstetrics and Gynecology Hospital wards selected trough census. The samples were categorized into two groups randomly. The intervention group participated in the short-term training workshop of stress management. The studied samples were measured in terms of occupational stress and satisfaction before, right after, and one month after the workshop. Occupational stress measurement was measured by Toft-Anderson occupational stress questionnaire (1981). Similarly, the occupational satisfaction was measured by JDI checklist developed by Stephen Robins (1994). In order to analyze the information, SPSS 16 together with descriptive statistics tests (frequency, percentile, mean, and standard deviation), independent sample t-tests, iterative measurement and Spearman correlation coefficient were used.  A total of 70 people (two 35-person groups) of midwives participated in this study. The findings revealed that there was a significant difference between the mean of scores of occupational stress between the two groups before and after the workshop (p=0.001). There was, however, no significant difference between the scores of satisfactions across the two groups. Training of skills of coping with stress including stress management can be effective in diminishing level of occupational stress. Mitigation of stress without catering for professional, occupational, organizational, and environmental factors would not lead to development of job satisfaction.

  9. STRESS IN THE TEACHING PROFESSION

    Directory of Open Access Journals (Sweden)

    Karina Wengel-Woźny

    2015-06-01

    Full Text Available Introduction. Teaching profession dates back to ancient times, when formulation of an ideal of a man with comprehensively developed personality was primarily based on such values as wisdom and knowledge. The profession of a teacher/master was influenced by many factors and underwent numerous transformations over the centuries. Aim. The aim is to assess the impact of stress and burnout at work and functioning of the teachers. Material and methods. The survey was conducted using a proprietary questionnaire consisting of 21 questions, in which the respondent select one of the following answers. The study assured full anonymity. The survey was conducted among a group of randomly selected teacher of primary, middle and secondary schools operating in the province of Opole. Results. As a result of conducted research it appeared that 54% of respondents many times a week feel stress related to their work. There are 28% of surveyed to sense nervous tension due to their professional occupation. 10% among them admit to experience this kind of stress up to twice a week whereas 8% of them tend to feel stressed once a week or less often. Conclusions. It is obvious that stress cannot be totally eliminated out of teacher profession. However we can reduce its size by applying a number of tools. These can be following: Implementation of educational programs dedicated for teachers- programs which aim at minimizing consequences of stress on teacher’s health and life as well as on their environment. Organizing of workshops of “coping with stress” and with difficult situations; education of behaving in situations of “overload”. The change of system of educating teachers and gaining professional competences.

  10. Effects of pulsed magnetic field treatment of soybean seeds on calli growth, cell damage, and biochemical changes under salt stress.

    Science.gov (United States)

    Radhakrishnan, Ramalingam; Leelapriya, Thasari; Kumari, Bollipo Diana Ranjitha

    2012-12-01

    The effects of magnetic field (MF) treatments of soybean seeds on calli growth, cell damage, and biochemical changes under salt stress were investigated under controlled conditions. Soybean seeds were exposed to a 1.0 Hz sinusoidal uniform pulsed magnetic field (PMF) of 1.5 µT for 5 h/day for 20 days. Non-treated seeds were considered as controls. For callus regeneration, the embryonic axis explants were taken from seeds and inoculated in a saline medium with a concentration of 10 mM NaCl for calli growth analysis and biochemical changes. The combined treatment of MF and salt stress was found to significantly increase calli fresh weight, total soluble sugar, total protein, and total phenol contents, but it decreased the ascorbic acid, lipid peroxidation, and catalase activity of calli from magnetically exposed seeds compared to the control calli. PMF treatment significantly improved calli tolerance to salt stress in terms of an increase in flavonoid, flavone, flavonole, alkaloid, saponin, total polyphenol, genistein, and daidzein contents under salt stress. The results suggest that PMF treatment of soybean seeds has the potential to counteract the adverse effects of salt stress on calli growth by improving primary and secondary metabolites under salt stress conditions. Copyright © 2012 Wiley Periodicals, Inc.

  11. RAGE polymorphisms and oxidative stress levels in Hashimoto's thyroiditis.

    Science.gov (United States)

    Giannakou, Maria; Saltiki, Katerina; Mantzou, Emily; Loukari, Eleni; Philippou, Georgios; Terzidis, Konstantinos; Lili, Kiriaki; Stavrianos, Charalampos; Kyprianou, Miltiades; Alevizaki, Maria

    2017-05-01

    Polymorphisms of the receptor for advanced glycation end products (RAGE) gene have been studied in various autoimmune disorders, but not in Hashimoto's thyroiditis. Also, increased oxidative stress has been described in patients with Hashimoto's thyroiditis. The aim of this study was to investigate the possible role of two common RAGE polymorphisms (-429T>C, -374T>A) in Hashimoto's thyroiditis; in parallel, we studied oxidative stress levels. A total of 300 consecutive euthyroid women were examined and classified into three groups: Hashimoto's thyroiditis with treatment (n = 96), Hashimoto's thyroiditis without treatment (n = 109) and controls (n = 95). For a rough evaluation of oxidative stress, total lipid peroxide levels in serum were measured. The -429T>C AluI and -374T>A MfeI polymorphisms of RAGE were studied in genomic DNA. Significant association of the RAGE system with Hashimoto's thyroiditis was found only with regard to the prevalence of the -429T>C, but not with -374T>A polymorphism. The levels of oxidative stress were significantly elevated in Hashimoto's thyroiditis patients under treatment. Further analysis demonstrated that an oxidative stress cut-off value of 590 μmol/L is associated with an increased risk of progression of Hashimoto's thyroiditis from euthyroidism to hypothyroidism; this risk is further increased in carriers of the RAGE -429T>C polymorphism. Our findings indicate that both examined risk factors may be implicated in the occurrence of Hashimoto's thyroiditis, but this covers only a fraction of the pathophysiology of the disease. © 2017 Stichting European Society for Clinical Investigation Journal Foundation.

  12. FAST TRACK SURGERY IN TOTAL KNEE ARTHROPLASTY - A REVIEW.

    Directory of Open Access Journals (Sweden)

    Pencho Kosev

    2015-08-01

    Full Text Available The number of orthopedic surgeons who are convinced in the need for significant changes in planned total knee arthroplasty (TKA is increasing slowly and steadily. A new approach to pain control has been developed over the past 10-15 years, and the introduction of techniques to reduce perioperative stress, and the use of minimally invasive surgical techniques can help limit postoperative complications and shorten recovery time. This type of optimization is regarded as Fast-track Care program, where improved healing process is particularly useful to comorbid patients.

  13. Engineering aspects of the salt diapirs; Aspectos de engenharia do diapirismo de sal

    Energy Technology Data Exchange (ETDEWEB)

    Borges, Ricardo Garske [Petroleo Brasileiro S.A. (PETROBRAS/CENPES), Rio de Janeiro, RJ (Brazil). Centro de Pesquisas e Desenvolvimento

    2012-07-01

    From the viewpoint of drilling and well bore integrity, salt presents new significant challenges of geomechanical nature. Saline rocks have a characteristic feature of deforming slowly over time, phenomenon known as creep. Salt bodies affect present geomechanical environment by change of the local stress state. This is due mainly by the fact that salt is not able to withstand deviatoric stresses. In particular, changes in stresses can happen in the vicinity of salt bodies which are of enough magnitude to affect the fracture gradient and well bore stability, the salt-sediment interface region being the one which concentrates the majority of drilling difficulties. During the drilling of an evaporitic section in an oil well, the accumulated strain over a time period can be enough to restrain the passing of the drilling column and even stuck it in an irretrievable way. After the well has been cased, the salt creep can manifest undesirably causing, in some situations, constraints to passing tools along the casing or even causing its rupture by collapse. In order to address this issue, this work seeks to assess how saline structures affect the present geomechanics environment through changes in the local state of stresses, in addition to the consequences to well bore drilling arising from this modified stress state inside and close to the salt. A historic summary is also presented concerning operational problems in well bore drilling in regions influenced by salt movement. (author)

  14. Development of computational methods of design by analysis for pressure vessel components

    International Nuclear Information System (INIS)

    Bao Shiyi; Zhou Yu; He Shuyan; Wu Honglin

    2005-01-01

    Stress classification is not only one of key steps when pressure vessel component is designed by analysis, but also a difficulty which puzzles engineers and designers at all times. At present, for calculating and categorizing the stress field of pressure vessel components, there are several computation methods of design by analysis such as Stress Equivalent Linearization, Two-Step Approach, Primary Structure method, Elastic Compensation method, GLOSS R-Node method and so on, that are developed and applied. Moreover, ASME code also gives an inelastic method of design by analysis for limiting gross plastic deformation only. When pressure vessel components design by analysis, sometimes there are huge differences between the calculating results for using different calculating and analysis methods mentioned above. As consequence, this is the main reason that affects wide application of design by analysis approach. Recently, a new approach, presented in the new proposal of a European Standard, CEN's unfired pressure vessel standard EN 13445-3, tries to avoid problems of stress classification by analyzing pressure vessel structure's various failure mechanisms directly based on elastic-plastic theory. In this paper, some stress classification methods mentioned above, are described briefly. And the computational methods cited in the European pressure vessel standard, such as Deviatoric Map, and nonlinear analysis methods (plastic analysis and limit analysis), are depicted compendiously. Furthermore, the characteristics of computational methods of design by analysis are summarized for selecting the proper computational method when design pressure vessel component by analysis. (authors)

  15. The effect of stress on magnetic Barkhausen activity in ferromagnetic steels

    International Nuclear Information System (INIS)

    Jiles, D.C.

    1989-01-01

    This paper presents results of measurements of the effect of uniaxial tensile stresses of up to 85 MPa on Barkhausen activity and magnetic properties of AISI 4130 and AISI 4140 steels. The results showed that the location of maximum Barkhausen activity was very close to the coercive point. Barkhausen peak height and the total number of pulses were affected by the stress, although there was considerable scatter in some of the results so that it was not clear how the peak height of the AISI 4130 varied with stress

  16. Testing the responses of four wheat crop models to heat stress at anthesis and grain filling.

    Science.gov (United States)

    Liu, Bing; Asseng, Senthold; Liu, Leilei; Tang, Liang; Cao, Weixing; Zhu, Yan

    2016-05-01

    Higher temperatures caused by future climate change will bring more frequent heat stress events and pose an increasing risk to global wheat production. Crop models have been widely used to simulate future crop productivity but are rarely tested with observed heat stress experimental datasets. Four wheat models (DSSAT-CERES-Wheat, DSSAT-Nwheat, APSIM-Wheat, and WheatGrow) were evaluated with 4 years of environment-controlled phytotron experimental datasets with two wheat cultivars under heat stress at anthesis and grain filling stages. Heat stress at anthesis reduced observed grain numbers per unit area and individual grain size, while heat stress during grain filling mainly decreased the size of the individual grains. The observed impact of heat stress on grain filling duration, total aboveground biomass, grain yield, and grain protein concentration (GPC) varied depending on cultivar and accumulated heat stress. For every unit increase of heat degree days (HDD, degree days over 30 °C), grain filling duration was reduced by 0.30-0.60%, total aboveground biomass was reduced by 0.37-0.43%, and grain yield was reduced by 1.0-1.6%, but GPC was increased by 0.50% for cv Yangmai16 and 0.80% for cv Xumai30. The tested crop simulation models could reproduce some of the observed reductions in grain filling duration, final total aboveground biomass, and grain yield, as well as the observed increase in GPC due to heat stress. Most of the crop models tended to reproduce heat stress impacts better during grain filling than at anthesis. Some of the tested models require improvements in the response to heat stress during grain filling, but all models need improvements in simulating heat stress effects on grain set during anthesis. The observed significant genetic variability in the response of wheat to heat stress needs to be considered through cultivar parameters in future simulation studies. © 2016 John Wiley & Sons Ltd.

  17. Psychological Stress and Mitochondria: A Systematic Review.

    Science.gov (United States)

    Picard, Martin; McEwen, Bruce S

    Mitochondria are multifunctional life-sustaining organelles that represent a potential intersection point between psychosocial experiences and biological stress responses. This article provides a systematic review of the effects of psychological stress on mitochondrial structure and function. A systematic review of the literature investigating the effects of psychological stress on mitochondrial function was conducted. The review focused on experimentally controlled studies allowing us to draw causal inference about the effect of induced psychological stress on mitochondria. A total of 23 studies met the inclusion criteria. All studies involved male laboratory animals, and most demonstrated that acute and chronic stressors influenced specific facets of mitochondrial function, particularly within the brain. Nineteen studies showed significant adverse effects of psychological stress on mitochondria and four found increases in function or size after stress. In humans, only six observational studies were available, none with experimental designs, and most only measured biological markers that do not directly reflect mitochondrial function, such as mitochondrial DNA copy number. Overall, evidence supports the notion that acute and chronic stressors influence various aspects of mitochondrial biology, and that chronic stress exposure can lead to molecular and functional recalibrations among mitochondria. Limitations of current animal and human studies are discussed. Maladaptive mitochondrial changes that characterize this subcellular state of stress are termed mitochondrial allostatic load. Prospective studies with sensitive measures of specific mitochondrial outcomes will be needed to establish the link between psychosocial stressors, emotional states, the resulting neuroendocrine and immune processes, and mitochondrial energetics relevant to mind-body research in humans.

  18. Association between Inflammatory Potential of Diet and Stress Levels in Adolescent Women in Iran.

    Science.gov (United States)

    Shivappa, Nitin; Hebert, James R; Rashidkhani, Bahram

    2017-02-01

    The relation between diet and stress has not been widely explored. In this study, we examined the association between the inflammatory potential of diet and levels of stress among adolescent girls in Iran. A total of 299 adolescent girls aged 15-18 years were recruited during 2014-2015. Stress was assessed using the Depression, Anxiety and Stress Scale (DASS)-21 scale. Data were analyzed as continuous DASS scores and as a dichotomous outcome with a cut-off value of 9. The dietary inflammatory index (DII) is a literature-derived population-based dietary. DII scores were index computed from dietary intake assessed using a validated food frequency questionnaire. Multivariable linear and logistic regressions were used to calculate beta estimates and odds ratios adjusting for potential confounding factors. In total, 84 girls (28% of the entire study sample) had at least a moderate level of stress symptoms (DASS > 9). Girls with the most pro-inflammatory diet (tertile 3) had higher DASS stress scores (β = 2.75; 95% CI = 1.05, 4.46) and were at 3.48 times (95% CI = 1.33, 9.09) risk of having at least moderate level of stress compared to girls with the most anti-inflammatory diets (tertile 1). These data suggest that Iranian adolescent girls with a pro-inflammatory diet, as shown by higher DII scores, had higher levels of stress and greater odds of having at least a moderate level of stress symptoms.

  19. The relationship between potency of oxidative stress and severity of dilated cardiomyopathy.

    Science.gov (United States)

    Demirbag, Recep; Yilmaz, Remzi; Erel, Ozcan; Gultekin, Unal; Asci, Durmus; Elbasan, Zafer

    2005-08-01

    It has been suggested that oxidative stress may have a role in the etiopathogenesis of congestive heart failure. To investigate and compare the oxidative-antioxidative status and oxidative stress index (OSI) of patients with idiopathic dilated cardiomyopathy (IDC) with those of healthy volunteers, and to determine the relationship between total antioxidant capacity (TAC) and ejection fraction (EF). Twenty-eight patients with IDC and 24 control subjects were enrolled in the study. Antioxidative status was evaluated by measuring the TAC and the vitamin C and thiol levels in the plasma. Oxidative status was evaluated by measuring the total peroxide level. The per cent ratio of TAC to total peroxide level was accepted as the OSI. EF was measured using Simpson's method. TAC and vitamin C and thiol levels of plasma were found to be significantly lower in patients with IDC than in control subjects (P total peroxide levels and OSIs were significantly higher in patients with IDC than in control subjects (P = 0.002 and P = 0.002, respectively). An important positive correlation was found between TAC and EF (r = 0.772; P total peroxide levels in patients. Oxidants are increased and antioxidants are decreased in patients with IDC; as a result, the oxidative-antioxidative balance is shifted to the oxidative side. There is a significant correlation between the potency of oxidative stress and the severity of IDC. It is believed that supplementation of antioxidants in the treatment of IDC may be helpful to these patients.

  20. Studies of internal stress in diamond films prepared by DC plasma chemical vapour deposition

    International Nuclear Information System (INIS)

    Wang Wanlu; Gao Jinying; Liao Kejun; Liu Anmin

    1992-01-01

    The internal stress in diamond thin films deposited by DC plasma CVD was studied as a function of methane concentration and deposited temperature. Experimental results have shown that total stress in diamond thin films is sensitive to the deposition conditions. The results also indicate that the compressive stress can be explained in terms of amorphous state carbon and hydrogen, and tensile stress is ascribed to the grain boundary relaxation model due to high internal surface area and microstructure with voids

  1. Perceived stress in patients with migraine: a case-control study.

    Science.gov (United States)

    Moon, Hye-Jin; Seo, Jong-Geun; Park, Sung-Pa

    2017-12-01

    Perceived stress is the most common trigger for migraine. The objective of this study was to examine the clinical significance of perceived stress in migraine patients. This is a case-control study. Consecutive migraine patients who visited a tertiary care hospital were enrolled for this study. They completed self-reported questionnaires including Perceived Stress Scale (PSS), 12-item Allodynia Symptom Checklist (ASC-12), Migraine Disability Assessment Scale (MIDAS), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), and Migraine-Specific Quality of Life Questionnaire (MSQ). Degree of perceived stress in migraine patients was measured and compared to that in healthy controls. Predictors for perceived stress and their impact on quality of life (QOL) of migraine patients were also determined. A total of 227 migraine patients were eligible for this study, including 103 (45.4%) who had chronic migraine (CM). Mean PSS score was significantly (p migraine is a critical factor for perceived stress. Perceived stress affects QOL of migraine patients.

  2. Residual stress measurement in 304 stainless steel weld overlay pipes

    International Nuclear Information System (INIS)

    Yen, H.J.; Lin, M.C.C.; Chen, L.J.

    1996-01-01

    Welding overlay repair (WOR) is commonly employed to rebuild piping systems suffering from intergranular stress corrosion cracking (IGSCC). To understand the effects of this repair, it is necessary to investigate the distribution of residual stresses in the welding pipe. The overlay welding technique must induce compressive residual stress at the inner surface of the welded pipe to prevent IGSCC. To understand the bulk residual stress distribution, the stress profile as a function of location within wall is examined. In this study the full destructive residual stress measurement technique -- a cutting and sectioning method -- is used to determine the residual stress distribution. The sample is type 304 stainless steel weld overlay pipe with an outside diameter of 267 mm. A pipe segment is cut from the circular pipe; then a thin layer is removed axially from the inner to the outer surfaces until further sectioning is impractical. The total residual stress is calculated by adding the stress relieved by cutting the section away to the stress relieved by axially sectioning. The axial and hoop residual stresses are compressive at the inner surface of the weld overlay pipe. Compressive stress exists not only at the surface but is also distributed over most of the pipe's cross section. On the one hand, the maximum compressive hoop residual stress appears at the pipe's inner surface. The thermal-mechanical induced crack closure from significant compressive residual stress is discussed. This crack closure can thus prevent IGSCC very effectively

  3. Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohepatitis

    OpenAIRE

    Horoz, Mehmet; Bolukbas, Cengiz; Bolukbas, Fusun F; Sabuncu, Tevfik; Aslan, Mehmet; Sarifakiogullari, Serpil; Gunaydin, Necla; Erel, Ozcan

    2005-01-01

    Abstract Background Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of nonalcoholic steatohepatitis. We aimed to investigate the total antioxidant response using a novel automated method in nonalcoholic steatohepatitis subjects. As a reciprocal measure, we also aimed to determine total peroxide level in the same plasma samples. Methods Twenty-two subjects with biopsy proven nonalco...

  4. Markers of Oxidative Stress and Antioxidant Defense in Romanian Patients with Type 2 Diabetes Mellitus and Obesity.

    Science.gov (United States)

    Picu, Ariana; Petcu, Laura; Ştefan, Simona; Mitu, Manuela; Lixandru, Daniela; Ionescu-Tîrgovişte, Constantin; Pîrcălăbioru, Grațiela Grădișteanu; Ciulu-Costinescu, Felicia; Bubulica, Maria-Viorica; Chifiriuc, Mariana Carmen

    2017-05-01

    Type 2 diabetes mellitus (T2DM) is strongly associated with obesity. The adipose tissue secretes bioactive adipokines leading to low grade inflammation, amplified by oxidative stress, which promotes the formation of advanced glycation end products and eventually leads to dyslipidemia and vascular complications. The aim of this study was to correlate anthropometric, biochemical and oxidative stress parameters in newly diagnosed (ND) T2DM patients and to investigate the role of oxidative stress in T2DM associated with obesity. A group of 115 ND- T2DM patients was compared to a group of 32 healthy subjects in terms of clinical, anthropometric, biochemical and oxidative stress parameters. ND-T2DM patients had significantly lower adiponectin, glutathione (GSH) and gluthatione peroxidase (GPx) and elevated insulin, proinsulin, HOMA-IR index, proinsulin/insulin (P/I) and proinsulin/adiponectin (P/A) ratio, fructosamine, and total oxidant status (TOS). The total body fat mass was positively correlated with total oxidant status (TOS). Positive correlations were found between TOS and glycated hemoglobin (HbA1c), and between TOS and glycaemia. Negative correlations were identified between: GPx and glycaemia, GPx and HbA1c, and also between GSH and fructosamine. The total antioxidant status was negatively correlated with the respiratory burst. The identified correlations suggest the existence of a complex interplay between diabetes, obesity and oxidative stress.

  5. Correlates of parental stress and psychopathology in pediatric epilepsy

    Directory of Open Access Journals (Sweden)

    Rania Shatla

    2011-01-01

    Full Text Available Background: Chronic conditions like epilepsy in a child can affect his/her entire family. The failure of the family members to adapt adequately to the unique demands of this childhood chronic illness can be considered as an important risk factor for development of psychopathology. Objectives: The objectives of this study were to study the profile of parenting stress in parents of children with epilepsy and its correlates; and, to examine the correlates of psychopathology in these children. Material and Methods: Twenty three epileptic children and their families were subjected to Parenting Stress Index (PSI, Scores for indices such as The Children′s Depression Inventory (CDI, Benton Visual Retention test, Spence anxiety scale for children, The Child Behavior Checklist (CBCL and Wechsler Intelligence Scale for Children were calculated. Results: Mean verbal and performance IQ score was 94, while the mean total IQ score was 95. Mean scores for all Wechsler IQ Scores as well as Benton Visual retention test were within the average range. Means for total internalizing CBCL t scores (M, Mean=70; Standard Deviation, SD=4.4, total externalizing CBCL t scores (M=60, SD=9.6, and total behavior problems CBCL t scores (M=67, SD=5.2 were above the standard cut off levels of 65 for clinical behavioral problems. Mean score on CDI was 42 ± 2. Scores of the PSI equal to or higher than 85 th percentile were considered pathologically high. Conclusion: The results of our study indicated that pediatric patients with epilepsy, specifically with intractable cases, are correlated with high levels of parental stress.

  6. Relationship between work stress and health in submariners

    Directory of Open Access Journals (Sweden)

    Nan-nan JIANG

    2013-09-01

    Full Text Available Objective To explore the relationship between work stress and health in submariners. Methods In April 2008, 272 submariners trained in a navy base were selected as study subjects by random group sampling method, and tested by primary personal information questionnaire, self-rated health measurement scale (SRHMS, self-developed submariners' work stressors questionnaire, and work stress self-rated scale. Physical health, mental health and social health of submariners were analyzed, and scores were compared with the norm of reference scores. Correlations were analyzed respectively between 10 items of submariners' general information (including age, length of military service, education degree, years at the present post, times of receiving awards, on-duty hours, off-duty hours, hours of sleep, lost days of leave, positive attitude to work and their physical health score, mental health score, social health score, total health score, as well as between 15 submariners' work stressors (including workrelated risks, diet problems, high temperature, humidity and noise in workplace, shortage of clean clothes, illness, losing contact with outside, lack of information about the task, lacking supports from family members, relationship problems, lack of involvement in task decisions, boring and dull work, on duty, heavy work, high quality of work, coping with unexpected threat and their physical health score, mental health score, social health score and total health score. Results No significant difference was found between submariners' SRHMS total score and the normal referenced score (t=0.56, P>0.05, but the physical health score and mental health score were significantly lower than normal referenced scores respectively (t=–2.172, P<0.05; t=–3.299, P<0.01, and the social health score was significantly higher than normal referenced score (t=9.331, P<0.001. The age, length of military service, years at present post of submariners were related

  7. X-ray fractography by using synchrotron radiation source. Residual stress distribution just beneath fatigue fracture surface

    International Nuclear Information System (INIS)

    Akita, Koichi; Yoshioka, Yasuo; Suzuki, Hiroshi; Sasaki, Toshihiko

    2000-01-01

    The residual stress distributions just beneath the fatigue fracture surface were measured using synchrotron radiation with three different wavelengths, i.e., three different penetration depths. The residual stress distributions were estimated from three kinds of diffraction data by the following process. First, a temporary residual stress distribution in the depth direction is assumed. Theoretical 2θ-sin 2 ψ diagrams for each wavelength, where each has a different penetration depth, are calculated by the cosψ method developed by one of the authors. The sum total of the differences between the theoretical and experimental values of the diffraction angle in 2θ-sin 2 ψ diagrams is calculated. This total value is minimized by changing the assumed stress distribution by the quasi-Newton optimization method. Finally, optimized 2θ-sin 2 ψ diagrams for each penetration depth and detailed stress distribution are determined. The true surface residual stress is obtained from this stress distribution. No effect of load ratio R (= P min /P max ) on the residual stresses of the fatigue fracture surfaces in low-carbon steels was observed when the sin 2 ψ method was used for stress measurement. However, the residual stresses became higher with increasing R when these were measured by the proposed method. On the basis of this, the stress intensity factor range, ΔK, can be estimated from the residual stress on the fatigue fracture surface. (author)

  8. [Parenting stress and the reliability of parental information in the diagnostics of children and adolescents with symptoms of psychiatric and behavioral disorders].

    Science.gov (United States)

    Irlbauer-Müller, Viktoria; Eichler, Anna; Stemmler, Mark; Moll, Gunther H; Kratz, Oliver

    2017-07-01

    Information from parents is regularly used in the diagnostic process of children and adolescents with psychiatric symptoms. But the reliability of this information is debatable, because the parents’ own stress can distort their perceptions of the child’s symptoms. For each of N = 68 children and adolescents (11–18 years) who were using mental health services for the first time, we evaluated the ratings of a parent and a professional clinician (internalizing, externalizing symptoms, total-problem score). In addition, parenting stress was scored on the Eltern-Belastungs-Inventars (EBI, Tröster, 2011), which measures both child-related stress and parent-related stress as well as total stress. Highly stressed parent ratings differed more from the clinicians’ ratings than the ratings of less stressed parents. Additionally, correlations showed that higher parenting stress resulted in larger differences between the parent’s and the clinician’s assessments. Multiple regressions proved the predictive value of child-caused parenting stress for these differences. These results apply for internalizing symptoms, externalizing symptoms, and total-problem score. Parenting stress should be evaluated systematically in order to carefully assess the value of the information from parents and to determine how it should be included in diagnostic and therapeutical decisions.

  9. A short-term supranutritional vitamin E supplementation alleviated respiratory alkalosis but did not reduce oxidative stress in heat stressed pigs

    Directory of Open Access Journals (Sweden)

    Fan Liu

    2018-02-01

    Full Text Available Objective Heat stress (HS triggers oxidative stress and respiratory alkalosis in pigs. The objective of this experiment was to study whether a short-term supranutritional amount of dietary vitamin E (VE can mitigate oxidative stress and respiratory alkalosis in heat-stressed pigs. Methods A total of 24 pigs were given either a control diet (17 IU/kg VE or a high VE (200 IU/kg VE; HiVE diet for 14 d, then exposed to thermoneutral (TN; 20°C, 45% humidity or HS (35°C, 35% to 45% humidity, 8 h daily conditions for 7 d. Respiration rate and rectal temperature were measured three times daily during the thermal exposure. Blood gas variables and oxidative stress markers were studied in blood samples collected on d 7. Results Although HiVE diet did not affect the elevated rectal temperature or respiration rate observed during HS, it alleviated (all p<0.05 for diet×temperature the loss of blood CO2 partial pressure and bicarbonate, as well as the increase in blood pH in the heat-stressed pigs. The HS reduced (p = 0.003 plasma biological antioxidant potential (BAP and tended to increase (p = 0.067 advanced oxidized protein products (AOPP in the heat-stressed pigs, suggesting HS triggers oxidative stress. The HiVE diet did not affect plasma BAP or AOPP. Only under TN conditions the HiVE diet reduced the plasma reactive oxygen metabolites (p<0.05 for diet× temperature. Conclusion A short-term supplementation with 200 IU/kg VE partially alleviated respiratory alkalosis but did not reduce oxidative stress in heat-stressed pigs.

  10. Oxidative stress of crystalline lens in rat menopausal model.

    Science.gov (United States)

    Acer, Semra; Pekel, Gökhan; Küçükatay, Vural; Karabulut, Aysun; Yağcı, Ramazan; Çetin, Ebru Nevin; Akyer, Şahika Pınar; Şahin, Barbaros

    2016-01-01

    To evaluate lenticular oxidative stress in rat menopausal models. Forty Wistar female albino rats were included in this study. A total of thirty rats underwent oophorectomy to generate a menopausal model. Ten rats that did not undergo oophorectomy formed the control group (Group 1). From the rats that underwent oophorectomy, 10 formed the menopause control group (Group 2), 10 were administered a daily injection of methylprednisolone until the end of the study (Group 3), and the remaining 10 rats were administered intraperitoneal streptozocin to induce diabetes mellitus (Group 4). Total oxidant status (TOS), total antioxidant capacity (TAC), and oxidative stress index (OSI) measurements of the crystalline lenses were analyzed. The mean OSI was the lowest in group 1 and highest in group 4. Nevertheless, the difference between the groups was not statistically significant in terms of OSI (p >0.05). The mean TOS values were similar between the groups (p >0.05), whereas the mean TAC of group 1 was significantly higher than that of the other groups (p <0.001). Our results indicate that menopause may not promote cataract formation.

  11. Increased oxidative stress in infants exposed to passive smoking.

    Science.gov (United States)

    Aycicek, Ali; Erel, Ozcan; Kocyigit, Abdurrahim

    2005-12-01

    The purpose of this study was to assess the effect of passive cigarette smoking on the oxidative and anti-oxidative status of plasma in infants. Eighty-four infants aged 6-28 weeks were divided into two groups: the study group included infants who had been exposed to passive smoking via at least five cigarettes per day for at least the past 6 weeks at home, while the control group included infants who had never been exposed to passive smoking. The antioxidative status of plasma was assessed by the measurement of individual antioxidant components: vitamin C, albumin, bilirubin, uric acid, thiol contents and total antioxidant capacity (TAC 1 and TAC 2). Oxidative status was assessed by the determination of total peroxide levels and the oxidative stress index (OSI 1 and OSI 2). Plasma vitamin C, thiol concentration and TAC 1 and TAC 2 levels were significantly lower, whereas plasma total peroxide levels and OSI 1 and OSI 2 were significantly higher, in passive smoking infants than in the controls (Pantioxidant defence system in infants, and exposes them to potent oxidative stress.

  12. Good stress, bad stress and oxidative stress: insights from anticipatory cortisol reactivity.

    Science.gov (United States)

    Aschbacher, Kirstin; O'Donovan, Aoife; Wolkowitz, Owen M; Dhabhar, Firdaus S; Su, Yali; Epel, Elissa

    2013-09-01

    Chronic psychological stress appears to accelerate biological aging, and oxidative damage is an important potential mediator of this process. However, the mechanisms by which psychological stress promotes oxidative damage are poorly understood. This study investigates the theory that cortisol increases in response to an acutely stressful event have the potential to either enhance or undermine psychobiological resilience to oxidative damage, depending on the body's prior exposure to chronic psychological stress. In order to achieve a range of chronic stress exposure, forty-eight post-menopausal women were recruited in a case-control design that matched women caring for spouses with dementia (a chronic stress model) with similarly aged control women whose spouses were healthy. Participants completed a questionnaire assessing perceived stress over the previous month and provided fasting blood. Three markers of oxidative damage were assessed: 8-iso-prostaglandin F(2α) (IsoP), lipid peroxidation, 8-hydroxyguanosine (8-oxoG) and 8-hydroxy-2'-deoxyguanosine (8-OHdG), reflecting oxidative damage to RNA/DNA respectively. Within approximately one week, participants completed a standardized acute laboratory stress task while salivary cortisol responses were measured. The increase from 0 to 30 min was defined as "peak" cortisol reactivity, while the increase from 0 to 15 min was defined as "anticipatory" cortisol reactivity, representing a cortisol response that began while preparing for the stress task. Women under chronic stress had higher 8-oxoG, oxidative damage to RNA (pstress and elevated oxidative stress damage, but only among women under chronic stress. Consistent with this model, bootstrapped path analysis found significant indirect paths from perceived stress to 8-oxoG and IsoP (but not 8-OHdG) via anticipatory cortisol reactivity, showing the expected relations among chronically stressed participants (p≤.01) Intriguingly, among those with low chronic stress

  13. Effects of mindfulness-based stress reduction on perceived stress and psychological health in patients with tension headache.

    Science.gov (United States)

    Omidi, Abdollah; Zargar, Fatemeh

    2015-11-01

    Programs for improving health status of patients with illness related to pain, such as headache, are often still in their infancy. Mindfulness-based stress reduction (MBSR) is a new psychotherapy that appears to be effective in treating chronic pain and stress. This study evaluated efficacy of MBSR in treatment of perceived stress and mental health of client who has tension headache. This study is a randomized clinical trial. Sixty patients with tension type headache according to the International Headache Classification Subcommittee were randomly assigned to the Treatment As Usual (TAU) group or experimental group (MBSR). The MBSR group received eight weekly classmates with 12-min sessions. The sessions were based on MBSR protocol. The Brief Symptom Inventory (BSI) and Perceived Stress Scale (PSS) were administered in the pre- and posttreatment period and at 3 months follow-up for both the groups. The mean of total score of the BSI (global severity index; GSI) in MBSR group was 1.63 ± 0.56 before the intervention that was significantly reduced to 0.73 ± 0.46 and 0.93 ± 0.34 after the intervention and at the follow-up sessions, respectively (P stress in comparison with the control group at posttest evaluation. The mean of perceived stress before the intervention was 16.96 ± 2.53 and was changed to 12.7 ± 2.69 and 13.5 ± 2.33 after the intervention and at the follow-up sessions, respectively (P stress in the TAU group at pretest was 15.9 ± 2.86 and that was changed to 16.13 ± 2.44 and 15.76 ± 2.22 at posttest and follow-up, respectively (P stress and improve general mental health in patients with tension headache.

  14. Alexithymia and Somatosensory Amplification Link Perceived Psychosocial Stress and Somatic Symptoms in Outpatients with Psychosomatic Illness

    Directory of Open Access Journals (Sweden)

    Mutsuhiro Nakao

    2018-05-01

    Full Text Available Background: Psychosomatic patients often complain of a variety of somatic symptoms. We sought to clarify the role of clinical predictors of complaints of somatic symptoms. Methods: We enrolled 604 patients visiting a psychosomatic outpatient clinic. The outcome was the total number of somatic symptoms, and the candidate clinical predictors were perceived psychosocial stress, alexithymia, somatosensory amplification, adaptation, anxiety, and depression. All participants completed questionnaires assessing the outcome and the predictors. Results: The average number of reported somatic symptoms was 4.8; the most frequent was fatigue (75.3%, followed by insomnia (56.1%, low-back pain (49.5%, headache (44.7%, and palpitations (43.1%. Multiple regression analysis showed that the total number of somatic symptoms was significantly associated with the degree of perceived psychosocial stress, alexithymia, somatosensory amplification, and depression. Also, structural equation models indicated links between excessive adaptation (via perceived psychosocial stress, alexithymia, and somatosensory amplification and the total number of somatic symptoms. Conclusion: The results suggested that the association between psychosocial stress and reported somatic symptoms is mediated by alexithymia and somatosensory amplification in psychosomatic patients.

  15. Proteomics analysis of alfalfa response to heat stress.

    Directory of Open Access Journals (Sweden)

    Weimin Li

    Full Text Available The proteome responses to heat stress have not been well understood. In this study, alfalfa (Medicago sativa L. cv. Huaiyin seedlings were exposed to 25 °C (control and 40 °C (heat stress in growth chambers, and leaves were collected at 24, 48 and 72 h after treatment, respectively. The morphological, physiological and proteomic processes were negatively affected under heat stress. Proteins were extracted and separated by two-dimensional polyacrylamide gel electrophoresis (2-DE, and differentially expressed protein spots were identified by mass spectrometry (MS. Totally, 81 differentially expressed proteins were identified successfully by MALDI-TOF/TOF. These proteins were categorized into nine classes: including metabolism, energy, protein synthesis, protein destination/storage, transporters, intracellular traffic, cell structure, signal transduction and disease/defence. Five proteins were further analyzed for mRNA levels. The results of the proteomics analyses provide a better understanding of the molecular basis of heat-stress responses in alfalfa.

  16. The association between changes in pressure pain sensitivity and changes in cardiovascular physiological factors associated with persistent stress

    DEFF Research Database (Denmark)

    Ballegaard, Søren; Petersen, Pernille B.; Harboe, Gitte S.

    2014-01-01

    Abstract Objectives. To evaluate the possible association between pressure pain sensitivity of the chest bone (PPS) and cardiovascular physiological factors related to persistent stress in connection with a three-month PPS-guided stress-reducing experimental intervention programme. Methods. Forty......-two office workers with an elevated PPS (≥ 60 arbitrary units) as a sign of increased level of persistent stress, completed a single-blinded cluster randomized controlled trial. The active treatment was a PPS (self-measurement)-guided stress management programme. Primary endpoints: Blood pressure (BP), heart...... between-group reductions were observed in respect to BP, HR, PRP, total and LDL cholesterol, and total number of elevated risk factors (p stress intervention method applied in this study induced a decrease in PPS which was associated with a clinically relevant decrease in resting...

  17. Adaptogenic potential of royal jelly in liver of rats exposed to chronic stress.

    Directory of Open Access Journals (Sweden)

    Douglas Carvalho Caixeta

    Full Text Available Restraint and cold stress increase both corticosterone and glycemia, which lead to oxidative damages in hepatic tissue. This study assessed the effect of royal jelly (RJ supplementation on the corticosterone level, glycemia, plasma enzymes and hepatic antioxidant system in restraint and cold stressed rats. Wistar rats were allocated into no-stress, stress, no-stress supplemented with RJ and stress supplemented with RJ groups. Initially, RJ (200mg/Kg was administered for fourteen days and stressed groups were submitted to chronic stress from the seventh day. The results showed that RJ supplementation decreases corticosterone levels and improves glycemia control after stress induction. RJ supplementation also decreased the body weight, AST, ALP and GGT. Moreover, RJ improved total antioxidant capacity, SOD activity and reduced GSH, GR and lipoperoxidation in the liver. Thus, RJ supplementation reestablished the corticosterone levels and the hepatic antioxidant system in stressed rats, indicating an adaptogenic and hepatoprotective potential of RJ.

  18. Self-Esteem and Academic Stress among Nursing Students.

    Science.gov (United States)

    Acharya Pandey, R; Chalise, H N

    2015-01-01

    Stress and self-esteem are common issues that everyone has to cope with at some time in their lives and they could also affect other things going on in a persons' life. Academic stress is psychological condition often experienced by college students as, to some extent, being multidimensional variables. Among others are self-esteem and psychological well-being which are considered to have influences in explaining why college students experience stress. Objective The objective of this study was to assess the self-esteem level and academic stress among the nursing students. Method This is a cross-sectional study carried out in 2012. Total respondents were 190 nursing students selected randomly from Kathmandu University. Academic stress was assed using 30-item Scale for Assessing Academic Stress (SAAS) and Self esteem was assessed using 10 item Rosenberg's Self-Esteem Scale. Information was collected through the self-administered questionnaire. The collected data was analyzed using SPSS version 16 software. Simple statistics measurement, percentage, means, correlation was used for the data analysis. Result This study shows mean age of the respondent's was 20.44±2.67 years. Majority (88%) of students getting financial support of less than NRs 6000 per month and 64% have low perceived family support. This study found mean score of self esteem and academic stress was 11.9 and 18.4 respectively. Further nearly 78% students have low self esteem and 74% have high academic stress. Significant variable for high academic stress and low self esteem were lower the age, lower the education and low perceived family support. Lower financial support has also high academic stress. Conclusion Nursing students have low self esteem and high academic stress. Intervention to lower the academic stress and increase the self esteem should be carried out so that the learning of students will be efficient.

  19. Silicon improves seed germination and alleviates oxidative stress of bud seedlings in tomato under water deficit stress.

    Science.gov (United States)

    Shi, Yu; Zhang, Yi; Yao, Hejin; Wu, Jiawen; Sun, Hao; Gong, Haijun

    2014-05-01

    The beneficial effects of silicon on plant growth and development under drought have been widely reported. However, little information is available on the effects of silicon on seed germination under drought. In this work, the effects of exogenous silicon (0.5 mM) on the seed germination and tolerance performance of tomato (Solanum lycopersicum L.) bud seedlings under water deficit stress simulated by 10% (w/v) polyethylene glycol (PEG-6000) were investigated in four cultivars ('Jinpengchaoguan', 'Zhongza No.9', 'Houpi L402' and 'Oubao318'). The results showed that the seed germination percentage was notably decreased in the four cultivars under water stress, and it was significantly improved by added silicon. Compared with the non-silicon treatment, silicon addition increased the activities of superoxide dismutase (SOD) and catalase (CAT), and decreased the production of superoxide anion (O2·) and hydrogen peroxide (H2O2) in the radicles of bud seedlings under water stress. Addition of silicon decreased the total phenol concentrations in radicles under water stress, which might contribute to the decrease of peroxidase (POD) activity, as observed in the in vivo and in vitro experiments. The decrease of POD activity might contribute to a less accumulation of hydroxyl radical (·OH) under water stress. Silicon addition also decreased the concentrations of malondialdehyde (MDA) in the radicles under stress, indicating decreased lipid peroxidation. These results suggest that exogenous silicon could improve seed germination and alleviate oxidative stress to bud seedling of tomato by enhancing antioxidant defense. The positive effects of silicon observed in a silicon-excluder also suggest the active involvement of silicon in biochemical processes in plants. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  20. TIBIAL PERIPROSTHETIC FRACTURE COMBINED WITH TIBIAL STEM STRESS FRACTURE FROM TOTAL KNEE ARTHROPLASTY

    OpenAIRE

    Fonseca, Fernando; Rebelo, Edgar; Completo, Antonio

    2011-01-01

    Total knee arthroplasty complications related to the prosthetic material are very rare, except for polyethylene wear. We report the case of a 58-year-old woman who came to the emergency service of our hospital with a periprosthetic tibial fracture (Mayo Clinic type I). Careful examination showed that this fracture was concomitantly associated with a tibial stem fatigue fracture. The prosthesis and the stem were sent to an independent biomechanics laboratory for evaluation. A finite-element CA...

  1. The impact of long working hours on psychosocial stress response among white-collar workers

    OpenAIRE

    LEE, Kyungjin; SUH, Chunhui; KIM, Jong-Eun; PARK, Jae Oh

    2016-01-01

    This study examined the association between long working hours and psychosocial stress responses. In total, 1,122 white-collar workers from a company in Korea completed self-administered questionnaires following a lecture about the study aim, procedures, and confidentiality. Psychosocial stress responses were evaluated using the Psychosocial Well-being Index - Short Form (PWI-SF), and psychosocial working conditions were evaluated with the Korean Occupational Stress Scale - Short Form (KOSS-S...

  2. Increased oxidative stress and its relation with collagen metabolism in knee osteoarthritis.

    Science.gov (United States)

    Altindag, Ozlem; Erel, Ozcan; Aksoy, Nurten; Selek, Sahabettin; Celik, Hakim; Karaoglanoglu, Mustafa

    2007-02-01

    The purpose of this study was to determine serum oxidative/antioxidative status in patients with knee osteoarthritis and its relation with prolidase activity, which plays an important role in collagen metabolism. Serum antioxidative status was evaluated by measuring total antioxidant capacity (TAC), thiol level and catalase enzyme activity in patients with osteoarthritis and in healthy controls. Serum oxidative status was evaluated by measuring total peroxide (TP) and lipid hydroperoxide. Oxidative stress index (OSI) was calculated. Prolidase enzyme activity was measured to investigate the collagen metabolism. Serum TAC, thiol level, catalase activity and prolidase activity were significantly lower in patients than in controls (P antioxidant parameters decreased in patients with osteoarthritis; therefore, these patients may be exposed to a potent oxidative stress. Decreased collagen metabolism may be related with oxidative stress, which has a role in the ethiopathogenesis and/or in the progression of the disease.

  3. Differential Exposure and Reactivity to Interpersonal Stress Predict Sex Differences in Adolescent Depression

    Science.gov (United States)

    Shih, Josephine H.; Eberhart, Nicole K.; Hammen, Constance L.; Brennan, Patricia A.

    2006-01-01

    This study tested the hypothesis that higher rates of depression in adolescent girls are explained by their greater exposure and reactivity to stress in the interpersonal domain in a large sample of 15-year-olds. Findings indicate that adolescent girls experienced higher levels of total and interpersonal episodic stress, whereas boys experienced…

  4. Adolescent Drinking and Adolescent Stress: A Domain-Specific Relationship in Northern Irish Schoolchildren

    Science.gov (United States)

    McKay, Michael Thomas; Cole, Jon C.

    2013-01-01

    Previous research has suggested an association between heightened levels of stress among adolescents and reduced levels of mental, physical and emotional well-being. This study sought to examine the relationship between 10 domains of adolescent stress and self-reported drinking behaviour. A total of 610 adolescents, aged 12-16 years old, were…

  5. Evaluation Of Oxidative Stress And Some Antioxidant Markers In Pregnant Cows Under Hot Summer Conditions

    International Nuclear Information System (INIS)

    TEAMA, F.E.

    2009-01-01

    Due to the heat stress and the decrease of antioxidants, the oxidative stress is produced which has a negative impact on the efficiency of productive and reproductive functions in cows. The aim of the present study is to evaluate the status of some antioxidant markers as well as measuring the level of progesterone as a criterion essential for duration of pregnancy besides the stress hormone cortisol in heat stressed pregnant and non-pregnant cows under hot summer conditions. Twelve healthy Brown Swiss cows with average body weight 350 kg were divided into two groups, six cows in each according to pregnancy status. The 1 st group consisted of 6 pregnant cows while the 2 nd included 6 non-pregnant cows. The rectal temperature (RT) was measured and blood samples were collected during three months to determine total antioxidant (TA), catalase (CAT) enzyme, malondialdehyde (MDA), cortisol and progesterone hormones.The result showed that there was an increase of rectal temperature for pregnant cows than in non-pregnant but didn't reach the critical value. In addition, there were significant increases in total antioxidant, progesterone and cortisol as compared with non-pregnant heat stressed cows while non-significant decrease in catalase enzyme in pregnant cows and non-significant increase in malondialdehyde in pregnant cows were observed. It could be concluded that total antioxidants, progesterone and cortisol hormones are a good biomarkers for oxidative stress in pregnant heat stressed cows while the non-significant changes in catalase and malondialdehyde may attributed to the small number of animals used and further studies on large number are recommended to evaluate the validity of those markers.

  6. Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis.

    Science.gov (United States)

    Wang, Qingzhong; Shelton, Richard C; Dwivedi, Yogesh

    2018-01-01

    Gene-environment interaction contributes to the risks of psychiatric disorders. Interactions between FKBP5 gene variants and early-life stress may enhance the risk not only for mood disorder, but also for a number of other behavioral phenotypes. The aim of the present study was to review and conduct a meta-analysis on the results from published studies examining interaction between FKBP5 gene variants and early-life stress and their associations with stress-related disorders such as major depression and PTSD. A literature search was conducted using PsychINFO and PubMed databases until May 2017. A total of 14 studies with a pooled total of 15109 participants met the inclusion criteria, the results of which were combined and a meta-analysis was performed using the differences in correlations as the effect measure. Based on literature, rs1360780, rs3800373, and rs9470080 SNPs were selected within the FKBP5 gene and systematic review was conducted. Based on the Comprehensive Meta-Analysis software, no publication bias was detected. Sensitivity analysis and credibility of meta-analysis results also indicated that the analyses were stable. The meta-analysis showed that individuals who carry T allele of rs1360780, C-allele of rs3800373 or T-allele of rs9470080 exposed to early-life trauma had higher risks for depression or PTSD. The effects of ethnicity, age, sex, and different stress measures were not examined due to limited sample size. These results provide strong evidence of interactions between FKBP5 genotypes and early-life stress, which could pose a significant risk factor for stress-associated disorders such as major depression and PTSD. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Prevalence of stress in Casablanca medical students: a cross-sectional study

    Science.gov (United States)

    Ben Loubir, Dalal; Serhier, Zeineb; Diouny, Samir; Battas, Omar; Agoub, Mohamed; Othmani, Mohammed Bennani

    2014-01-01

    Introduction Recently, an important literature data has reported that medical students experience stress more than students in other disciplines. In contrast, there is a significant shortage of the stress impact on the academic performance. The primary purpose of our study was to determine the prevalence of stress among Casablanca Medical students and to investigate if there is an association between stress and academic skills. Methods A total of 275 participants studying at Casablanca Medical School were included. The study was conducted using a self-administered, anonymous questionnaire, which included four subscales on academic skills perception (Academic competence, Test competence, Time management and Strategic study habits) and a Test Anxiety scale to assess the degree of stress related to exams among medical students. Results The overall findings showed that 52.7% of respondents were stressed by examinations, and the highest stress prevalence was among the fifth-year medical students. Measures of comparative stress degrees between male and female students did not show any statistical significant differences (p=0.34). Correlation analysis revealed negative association between stress and academic competence (-0.394), test competence (-0.426), time management (-0.240), strategic study (-0.183) respectively (peducators and psychologists have to increase clinical awareness of stress among medical students, by establishing strategies for stress management. PMID:25767668

  8. Risk of stress urinary incontinence twelve years after the first pregnancy and delivery.

    Science.gov (United States)

    Viktrup, Lars; Rortveit, Guri; Lose, Gunnar

    2006-08-01

    To estimate the impact of onset of stress urinary incontinence in first pregnancy or postpartum period, for the risk of symptoms 12 years after the first delivery. In a longitudinal cohort study, 241 women answered validated questions about stress urinary incontinence after first delivery and 12 years later. Twelve years after first delivery the prevalence of stress urinary incontinence was 42% (102 of 241). The 12-year incidence was 30% (44 of 146). The prevalence of stress urinary incontinence 12 years after first pregnancy and delivery was significantly higher (Ppregnancy (56%, 37 of 66) and in women with onset shortly after delivery (78%, 14 of 18) compared with those without initial symptoms (30%, 44 of 146). In 70 women who had onset of symptoms during first pregnancy or shortly after the delivery but remission 3 months postpartum, a total of 40 (57%) had stress urinary incontinence 12 years later. In 11 women with onset of symptoms during the first pregnancy or shortly after delivery but no remission 3 months postpartum, a total of 10 (91%) had stress urinary incontinence 12 years later. Cesarean during first delivery was significantly associated with a lower risk of incontinence. Other obstetric factors were not significantly associated with the risk of incontinence 12 years later. Patients who were overweight before their first pregnancy were at increased risk. Onset of stress urinary incontinence during first pregnancy or puerperal period carries an increased risk of long-lasting symptoms.

  9. The predictive value of early maladaptive schemas in paranoid responses to social stress.

    Science.gov (United States)

    Sundag, Johanna; Ascone, Leonie; Lincoln, Tania M

    2018-01-01

    Social stress and negatively valenced cognitive representations of the self (self-schemas) play an important role in the formation of delusions. However, it has not been investigated whether and which self-schemas explain paranoid responses to social stress. Building on the framework of schema theory, the aim of this study was thus to investigate whether more pronounced early maladaptive schemas (EMSs) were associated with increased paranoid ideation after a social stress induction in patients with persecutory delusions (PD). Patients with PD (n = 20) and healthy controls (n = 40) were assessed for EMSs with the Young Schema Questionnaire. They were then exposed to a social stress situation in which they were socially excluded in a Cyberball paradigm. Prior to and after the social stress induction, paranoid symptoms were assessed. Patients with PD responded with a stronger increase in paranoia and revealed a significantly higher EMS total score compared to the healthy controls. As expected, higher increases in paranoia following the social stress were accounted for by higher EMS total scores. Exploratory analyses showed that particularly the specific EMSs Defectiveness/Shame and Enmeshment/Undeveloped Self were associated with the increase in paranoia. EMSs are associated with stress-related symptom increases in patients with PD. It thus seems worthwhile to further investigate the relevance of specific schemas for paranoia. The findings also suggest that addressing EMSs in psychological treatment of patients with PD holds potential. Copyright © 2017 John Wiley & Sons, Ltd.

  10. Mental health of recently resettled refugees from the Middle East in Sweden: the impact of pre-resettlement trauma, resettlement stress and capacity to handle stress.

    Science.gov (United States)

    Lindencrona, Fredrik; Ekblad, Solvig; Hauff, Edvard

    2008-02-01

    The pathways to symptoms of common mental disorder and post-traumatic stress symptoms among refugees during resettlement need to be better specified. We aim to identify models of these different mental health outcomes among refugees during resettlement, taking pre-migration, migration and post-migration stress conditions, a person's capacity to handle such stress and socio-demographic variables into consideration. A new questionnaire developed to better cover resettlement stress, as well as pre-resettlement trauma exposures and different measures of a person's capacity to handle stress, was administered to 124 Middle Eastern refugees that had been granted permanent residency in Sweden only a few months before responding. We found four dimensions of resettlement stress: social and economic strain, alienation, discrimination and status loss and violence and threats in Sweden, that account for 62% of the total variance in resettlement stress. Social and economic strain and alienation are important for explaining symptoms of common mental disorder. In the model of core post-traumatic stress symptoms, pre-resettlement trauma exposure seems to have the strongest impact. A person's capacity to handle stress plays significant, direct and mediating roles in both models. The impact of resettlement stressors in the context of the whole migration process for different mental health outcomes is discussed.

  11. Psychosocial stress affects the acquisition of cerebellar-dependent sensorimotor adaptation.

    Science.gov (United States)

    Gheorghe, Delia A; Panouillères, Muriel T N; Walsh, Nicholas D

    2018-03-27

    Despite being overlooked in theoretical models of stress-related disorders, differences in cerebellar structure and function are consistently reported in studies of individuals exposed to current and early-life stressors. However, the mediating processes through which stress impacts upon cerebellar function are currently unknown. The aim of the current experiment was to test the effects of experimentally-induced acute stress on cerebellar functioning, using a classic, forward saccadic adaptation paradigm in healthy, young men and women. Stress induction was achieved by employing the Montreal Imaging Stress Task (MIST), a task employing mental arithmetic and negative social feedback to generate significant physiological and endocrine stress responses. Saccadic adaptation was elicited using the double-step target paradigm. In the experiment, 48 participants matched for gender and age were exposed to either a stress (n = 25) or a control (n = 23) condition. Saliva for cortisol analysis was collected before, immediately after, and 10, and 30 min after the MIST. Saccadic adaptation was assessed approximately 10 min after stress induction, when cortisol levels peaked. Participants in the stress group reported significantly more stress symptoms and exhibited greater total cortisol output compared to controls. The stress manipulation was associated with slower learning rates in the stress group, while control participants acquired adaptation faster. Learning rates were negatively associated with cortisol output and mood disturbance. Results suggest that experimentally-induced stress slowed acquisition of cerebellar-dependent saccadic adaptation, related to increases in cortisol output. These 'proof-of-principle' data demonstrate that stress modulates cerebellar-related functions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Total Antioxidant Capacity and Total Oxidant Status in Saliva of Periodontitis Patients in Relation to Bacterial Load

    Science.gov (United States)

    Zhang, Taowen; Andrukhov, Oleh; Haririan, Hady; Müller-Kern, Michael; Liu, Shutai; Liu, Zhonghao; Rausch-Fan, Xiaohui

    2016-01-01

    The detection of salivary biomarkers has a potential application in early diagnosis and monitoring of periodontal inflammation. However, searching sensitive salivary biomarkers for periodontitis is still ongoing. Oxidative stress is supposed to play an important role in periodontitis progression and tissue destruction. In this cross-sectional study, we investigated total antioxidant capacity (TAC) and total oxidant status (TOS) in saliva of periodontitis patients compared to healthy controls and their relationship with periodontopathic bacteria and periodontal disease severity. Unstimulated saliva was collected from 45 patients with generalized severe periodontitis and 37 healthy individuals and the TAC/TOS were measured. In addition, salivary levels of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Fusobacterium nucleatum in saliva were measured. Salivary TAC was lower in periodontitis patients compared to healthy controls. Moreover, a significant negative correlation of salivary TAC with clinical attachment loss was observed in periodontitis patients. No significant difference in the salivary TOS was observed between periodontitis patients and healthy controls. Bacterial load was enhanced in periodontitis patients and exhibited correlation with periodontal disease severity but not with salivary TAC/TOS. Our data suggest that changes in antioxidant capacity in periodontitis patients are not associated with increased bacterial load and are probably due to a dysregulated immune response. PMID:26779448

  13. Total antioxidant capacity and total oxidant status in saliva of periodontitis patients in relation to bacterial load

    Directory of Open Access Journals (Sweden)

    Taowen eZhang

    2016-01-01

    Full Text Available The detection of salivary biomarkers has a potential application in early diagnosis and monitoring of periodontal inflammation. However, searching sensitive salivary biomarkers for periodontitis is still ongoing. Oxidative stress is supposed to play an important role in periodontitis progression and tissue destruction. In this cross-sectional study, we investigated total antioxidant capacity (TAC and total oxidant status (TOS in saliva of periodontitis patients compared to healthy controls and their relationship with periodontopathic bacteria and periodontal disease severity. Unstimulated saliva was collected from 45 patients with generalized severe periodontitis and 37 healthy individuals and the TAC/TOS were measured. In addition, salivary levels of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Fusobacterium nucleatum in saliva were measured. Salivary TAC was lower in periodontitis patients compared to healthy controls. Moreover, a significant negative correlation of salivary TAC with clinical attachment loss was observed in periodontitis patients. No significant difference in the salivary TOS was observed between periodontitis patients and healthy controls. Bacterial load was enhanced in periodontitis patients and exhibited correlation with periodontal disease severity but not with salivary TAC/TOS. Our data suggest that changes in antioxidant capacity in periodontitis patients are not associated with increased bacterial load and are probably due to a dysregulated immune response.

  14. Plasma total antioxidant capacity (TAC) in obese Malaysian subjects.

    Science.gov (United States)

    Lim, S H; Fan, S H; Say, Y H

    2012-12-01

    There is a pressing need to better understand the complex biochemical pathways that lead to the pathogenesis of obesity. Increased oxidative stress and decreased antioxidant capacity have been identified to be associated with obesity. Therefore, the objectives of this study were to determine the plasma total antioxidant capacity (TAC) levels of Malaysian subjects and to evaluate its potential association with obesity and related anthropometric measurements. Plasma TAC of 362 multi-ethnic Malaysian subjects from the Kampar Health Clinic (138 males, 224 females; 124 ethnic Malays, 152 Chinese, 86 Indians; 192 non-obese, 170 obese) was measured using Trolox equivalent antioxidant capacity (TEAC) 96-well plate assay. Plasma TAC was significantly lower in obese subjects (M +/- SE = 292 +/- 10.4 micromol/L) compared to non-obese subjects (397 +/- 8.58 micromol/L), whereas it was significantly higher in males and those in the 21-30 age group. Those with salty food preference and practising a strict vegetarian diet also had significantly higher plasma TAC. However, no association was found for other dietary habits (coffee intake) and lifestyle factors (physical activity, smoking). Plasma TAC was also significantly negatively correlated with diastolic blood pressure, waist and hip circumferences, weight, body mass index, total body fat, % subcutaneous fat, visceral fat level, resting metabolism and % skeletal muscle. Plasma TAC was found to be associated with obesity, strict vegetarian practice, salty food preference and all obesity anthropometric indicators, except systolic blood pressure and pulse rate. Obese people have decreased plasma TAC indicating a compromised systemic antioxidant defence and increased oxidative stress.

  15. 13 reasons why the brain is susceptible to oxidative stress

    OpenAIRE

    James Nathan Cobley; Maria Luisa Fiorello; Damian Miles Bailey

    2018-01-01

    The human brain consumes 20% of the total basal oxygen (O2) budget to support ATP intensive neuronal activity. Without sufficient O2 to support ATP demands, neuronal activity fails, such that, even transient ischemia is neurodegenerative. While the essentiality of O2 to brain function is clear, how oxidative stress causes neurodegeneration is ambiguous. Ambiguity exists because many of the reasons why the brain is susceptible to oxidative stress remain obscure. Many are erroneously understood...

  16. Occupational Stress and Coping Behaviours Among Dentists in Kerman, Iran

    Directory of Open Access Journals (Sweden)

    Shiva Pouradeli

    2016-08-01

    Full Text Available Objectives: Recognising causes of stress can help prevent associated adverse effects. This study aimed to investigate causes of occupational stress and coping behaviours among general dentists in Iran. Methods: This cross-sectional study was carried out from April to December 2014. A modified version of the Occupational Stress Indicator questionnaire was used to assess causes of stress and coping behaviours among 142 general dentists in Kerman, Iran. Results: A total of 93 dentists participated in the study (response rate: 65.5%. Of these, 58.9% reported often being stressed. The mean general stress score was 63.33 ± 19.99. The most common causes of stress were maintaining high levels of concentration while working (65.6%, time pressures (64.5%, concern over their ability to deliver dental services in future (60.2% and rising costs (59.1%. No significant relationships between stress and gender, age, workplace or working hours per week were noted (P >0.05. However, there was a significant correlation between general stress scores and years of job experience (P = 0.05 and number of patients treated daily (P = 0.03. The most common methods for coping with stress were resting (71.0%, sports (45.2% and entertainment (43.0%. Most dentists felt that stress management courses could help to reduce stress (89.7%. Conclusion: General dentists in Kerman were subject to many sources of stress in their workplaces, with significant relationships between stress scores and years of work experience and number of patients treated daily. Dentists should be encouraged to participate in stress management courses to help alleviate stress.

  17. Screening for Osmotic Stress Responses in Rice Varieties under Drought Condition

    OpenAIRE

    Simon Swapna; Korukkanvilakath Samban Shylaraj

    2017-01-01

    Drought is the major abiotic stress factor that limits rice production worldwide. To evaluate the osmotic stress responses in rice varieties under drought condition, a total of 42 high-yielding rice varieties were collected from various research stations of Kerala Agricultural University in India. The experimental setup comprises of initial hydroponic treatments at different osmotic potentials, artificially induced by desired strengths of polyethylene glycol (PEG6000), and followed by the pot...

  18. Differential expression of genes regulated in response to drought stress in diploid cotton (Gossypium arboreum) (abstract)

    International Nuclear Information System (INIS)

    Hussain, T.; Majeed, A.; Maqbool, A.; Hussain, S.S.; Ali, T.; Riazuddin, S.

    2005-01-01

    Negative effects on the Water status of plants is one of the most common and deleterious stresses experienced by wild and cultivated plants throughout the World. Our project is designed to identify, clone and characterize gene sequences regulated in response to Water stress (e.g., drought). We used the differential-display reverse transcriptase polymerase chain reaction (DD-RT- PCA) methodology to accomplish our Objectives. Structural and functional characterization of environmental stress-induced genes has contributed to a better understanding of how plants respond and adapt to different abiotic stresses. Differential display was used to compare overall difference in gene expression between draught stressed and unstressed (control) plants of diploid Cotton (Gossypium arboreum). DDRT-PCR product from stressed and unstressed samples resolved side by side on 6% PAGE to compare qualitative and quantitative difference in mRNA expression. A total of 81 primer combinations were tested. DDRT -PCR enabled us to identify differentially expressed transcripts between water stressed and non-stressed cotton seedlings. PAGE revealed a total of 347 DNA transcripts in stressed samples (New Transcripts) while 110 down regulated and 209 up regulated DNA transcripts were also recorded. Similarly. 22 DNA transcripts were identified based on the comparative study of PAGE and Agarose gel electrophoresis. These sequences showed various degree homology With draught tolerant genes in the gene bank. (author)

  19. Oxidative Stress ‑a Phenotypic Hallmark of Fanconi Anemia and ...

    African Journals Online (AJOL)

    Keywords: Down syndrome, Oxidative DNA damage, Oxidative stress. Access this ... higher MDA levels (P < 0.01) and non significantly lower total antioxidant .... in their study that carotenoids and carotenoid-rich foods can influence DNA ...

  20. Oxidative and endoplasmic reticulum stress is impaired in leukocytes from metabolically unhealthy vs healthy obese individuals.

    Science.gov (United States)

    Bañuls, C; Rovira-Llopis, S; Lopez-Domenech, S; Diaz-Morales, N; Blas-Garcia, A; Veses, S; Morillas, C; Victor, V M; Rocha, M; Hernandez-Mijares, A

    2017-10-01

    Oxidative stress and inflammation are related to obesity, but the influence of metabolic disturbances on these parameters and their relationship with endoplasmic reticulum (ER) stress is unknown. Therefore, this study was performed to evaluate whether metabolic profile influences ER and oxidative stress in an obese population with/without comorbidities. A total of 113 obese patients were enrolled in the study; 29 were metabolically healthy (MHO), 53 were metabolically abnormal (MAO) and 31 had type 2 diabetes (MADO). We assessed metabolic parameters, proinflammatory cytokines (TNFα and IL-6), mitochondrial and total reactive oxygen species (ROS) production, glutathione levels, antioxidant enzymes activity, total antioxidant status, mitochondrial membrane potential and ER stress marker expression levels (glucose-regulated protein (GRP78), spliced X-box binding protein 1 (XBP1), P-subunit 1 alpha (P-eIF2α) and activating transcription factor 6 (ATF6). The MAO and MADO groups showed higher blood pressure, atherogenic dyslipidemia, insulin resistance and inflammatory profile than that of MHO subjects. Total and mitochondrial ROS production was enhanced in MAO and MADO patients, and mitochondrial membrane potential and catalase activity differed significantly between the MADO and MHO groups. In addition, decreases in glutathione levels and superoxide dismutase activity were observed in the MADO vs MAO and MHO groups. GRP78 and CHOP protein and gene expression were higher in the MAO and MADO groups with respect to MHO subjects, and sXBP1 gene expression was associated with the presence of diabetes. Furthermore, MAO patients exhibited higher levels of ATF6 than their MHO counterparts. Waist circumference was positively correlated with ATF6 and GRP78, and A1c was positively correlated with P-Eif2α. Interestingly, CHOP was positively correlated with TNFα and total ROS production and GRP78 was negatively correlated with glutathione levels. Our findings support the

  1. WeChat Addiction Suppresses the Impact of Stressful Life Events on Life Satisfaction.

    Science.gov (United States)

    Li, Bi; Wu, Yan; Jiang, Shengyi; Zhai, Huizhen

    2018-03-01

    The current study examined the influences of stressful life events and WeChat addiction on life satisfaction, and investigated the mediating role of WeChat addiction on the relationship between the two research variables. A total of 463 undergraduates completed self-reported scales for stressful life events, WeChat addiction, and life satisfaction. Structural equation modeling was used to analyze the questionnaire data. The results showed the suppressing effect of WeChat addiction on the negative impact of stressful life events on life satisfaction. Stressful life events affect life satisfaction both directly and indirectly. Stressful life events are positively associated with WeChat addiction, which exerts positive impact on life satisfaction. The contributions of the findings are discussed.

  2. Psychosocial stress is associated with obesity and diet quality in Hispanic/Latino adults

    Science.gov (United States)

    Isasi, Carmen R; Parrinello, Christina M; Jung, Molly M; Carnethon, Mercedes R; Birnbaum-Weitzman, Orit; Espinoza, Rebeca A; Penedo, Frank J; Perreira, Krista M; Schneiderman, Neil; Sotres-Alvarez, Daniela; Van Horn, Linda; Gallo, Linda C

    2014-01-01

    Purpose To examine the association of psychosocial stress with obesity, adiposity, and dietary intake in a diverse sample of Hispanic/Latino adults. Methods Participants were 5077 men and women, 18–74 years old, from diverse Hispanic/Latino ethnic backgrounds. Linear regression models were used to assess the association of ongoing chronic stressors and recent perceived stress with measures of adiposity (waist circumference and percentage body fat) and dietary intake (total energy, saturated fat, alternative healthy eating index [AHEI-2010]). Multinomial logistic models were used to describe the odds of obesity or overweight relative to normal weight. Results Greater number of chronic stressors and greater perceived stress were associated with higher total energy intake. Greater recent perceived stress was associated with lower diet quality as indicated by AHEI-2010 scores. Compared to no stressors, reporting ≥ 3 chronic stressors was associated with higher odds of being obese (OR = 1.5, 95%CI 1.01–2.1), greater waist circumference (β = 3.3, 95%CI 1.0–5.5) and percentage body fat (β = 1.5, 95%CI 0.4, 2.6). Conclusions The study found an association between stress and obesity and adiposity measures, suggesting that stress management techniques may be useful in obesity prevention and treatment programs that target Hispanic/Latino populations. PMID:25487969

  3. Accelerometer-determined physical activity and the cardiovascular response to mental stress in children.

    Science.gov (United States)

    Spartano, Nicole L; Heffernan, Kevin S; Dumas, Amy K; Gump, Brooks B

    2017-01-01

    Cardiovascular reactivity has been associated with future hypertension and cardiovascular mortality. Higher physical activity (PA) has been associated with lower cardiovascular reactivity in adults, but little data is available in children. The purpose of this study was to examine the relationship between PA and cardiovascular reactivity to mental stress in children. Cross-sectional study. This study sample included children from the Oswego Lead Study (n=79, 46% female, 9-11 years old). Impedance cardiography was performed while children participated in a stress response protocol. Children were also asked to wear Actigraph accelerometers on their wrists for 3 days to measure intensity and duration of PA and sedentary time. In multivariable models, moderate to vigorous (MV) PA was associated with lower body mass index (BMI) percentile and lower total peripheral resistance (TPR) response to stress (beta=-0.025, p=0.02; beta=-0.009, p=0.05). After additional adjustment for BMI, MVPA was also associated with lower diastolic blood pressure response to stress (beta=-0.01, p=0.03). Total PA and sedentary time were not associated with BMI or cardiovascular responses to stress. A modest, inverse relation of PA to vascular reactivity to mental stress was observed in children. These data provide confirmatory evidence that the promotion of PA recommendations for children are important for cardiovascular health. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  4. Psychosocial stress is associated with obesity and diet quality in Hispanic/Latino adults.

    Science.gov (United States)

    Isasi, Carmen R; Parrinello, Christina M; Jung, Molly M; Carnethon, Mercedes R; Birnbaum-Weitzman, Orit; Espinoza, Rebeca A; Penedo, Frank J; Perreira, Krista M; Schneiderman, Neil; Sotres-Alvarez, Daniela; Van Horn, Linda; Gallo, Linda C

    2015-02-01

    To examine the association of psychosocial stress with obesity, adiposity, and dietary intake in a diverse sample of Hispanic/Latino adults. Participants were 5077 men and women, aged 18 to 74 years, from diverse Hispanic/Latino ethnic backgrounds. Linear regression models were used to assess the association of ongoing chronic stressors and recent perceived stress with measures of adiposity (waist circumference and percentage body fat) and dietary intake (total energy, saturated fat, alternative healthy eating index-2010). Multinomial logistic models were used to describe the odds of obesity or overweight relative to normal weight. Greater number of chronic stressors and greater perceived stress were associated with higher total energy intake. Greater recent perceived stress was associated with lower diet quality as indicated by alternative healthy eating index-2010 scores. Compared with no stressors, reporting three or more chronic stressors was associated with higher odds of being obese (odds ratio = 1.5, 95% confidence interval [CI] 1.01-2.1), greater waist circumference (β = 3.3, 95% CI 1.0-5.5), and percentage body fat (β = 1.5, 95% CI 0.4-2.6). The study found an association between stress and obesity and adiposity measures, suggesting that stress management techniques may be useful in obesity prevention and treatment programs that target Hispanic/Latino populations. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. The Effect of Stress Management Training Program on Stress Coping Styles among the Adolescents in Prison in Turkey.

    Science.gov (United States)

    Öztürk, Özlem; Ocakçı, Ayşe F

    2017-08-01

    This study was performed to determine the effects of a stress management training program that was administered to adolescents in prison. This was a semi-experimental study that used pretests and posttests in controlled groups; it was performed between June 2012 and March 2013 in a closed prison for children and adolescents. The study was completed with the participation of 73 adolescents (36 in the experimental group and 37 in the control group). Adolescent Lifestyle Profile scale and the Stress Coping Styles Scale were used as the data collection tools. The Stress Management Training Program was developed by the researchers and carried out for 2 weeks, a total of 10 sessions of 40 min each. The scales were administered before the program was implemented, immediately after the program and 1 month following the program. Although there were no statistically significant differences between the mean Stress Coping Styles Scale scores of the experimental and control groups before the intervention (p > 0.05), a statistically significant difference was found after the intervention and at re-test (p management. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  6. Performance Enhancement with Low Stress and Anxiety Modulated by Cognitive Flexibility

    Science.gov (United States)

    Park, Hyung Woo; Kee, Baik Seok; Na, Churl; Na, Do-Hyun E.; Zaichkowsky, Leonard

    2011-01-01

    Objective The purpose of this study was to compare cognitive flexibility abilities, stress, and anxiety between starters and non-starter athletes. Methods A total of 30 male professional-soccer and 40 professional-baseball athletes were recruited. Wisconsin Card Sorting Test (WCST) and Trail Making Test A & B (TMT A & B) were administered to assess cognitive flexibility during competition. The Korean version of the STAI form Y (STAI-KY) and Visual analogue scale for anxiety and stress were used to assess the anxiety and stress. Results The starter group had better cognitive function (fewer perseverative errors and rapid TMTB times) (Z=3.32, panxiety (F=4.34, p=0.01; F=6.61, pcognitive performances were negatively correlated with stress and anxiety. Current results suggested that cognitive flexibility would enhance human performance by modulation of the anxiety and stress during competition. PMID:21994509

  7. Updated of the events tree of total loss of power at the site, SBO, taking into account the results of stress tests and methodological updates, convolution, and hydraulic power recovery from model RCPs; Actualizacion del arbol de sucesos de perdida total de suministro electro en el emplazamiento, SBO, teniendo en cuenta los resultados de los estres tests y actualizaciones metodologicas, convolucion, recuperacion desde centrales hidraulicas y modelo de sellos de las RCPs

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Lorenzo, M. A.; Perez Martin, F.

    2013-07-01

    In this paper, is described a tree of events to an accident loss total power at the site (SBO) considering, first the results of stress tests arising from the Fukushima accident and moreover, various methodological updates related to this initiating event.

  8. Protective Effects of Alkaloid Compounds from Nelumbinis Plumula on tert-Butyl Hydroperoxide-Induced Oxidative Stress

    Directory of Open Access Journals (Sweden)

    Ze-Bin Guo

    2013-08-01

    Full Text Available This study was conducted to investigate the effect of Nelumbinis Plumula total alkaloid (NPA and its main alkaloid components on oxidative stress induced by tert-butyl hydroperoxide (t-BHP in the human hepatocellular HepG2 cell line. According to HPLC analysis, several major alkaloid compounds such as liensinine, isoliensinine and neferine were present in NPA. The cytotoxic effects in 0.55 mM t-BHP-induced HepG2 cells were significantly inhibited by NPA and the major compound in NPA, neferine, showed the strongest activities. The protective effect of neferine against oxidative stress induced by t-BHP may be associated with decreased ROS formation, TBARS generation, LDH release and increased GSH levels, suggesting their involvement of the cytoprotective on oxidative stress. The effects were comparable with quercetin, which was used as positive control. Overall, total alkaloid and alkaloid compounds from Nelumbinis Plumula displayed a significant cytoprotective effect against oxidative stress. Further study is needed to elucidate the relationship between the chemical structures of the components in NPA and their protective effect on oxidative stress.

  9. Sleep restriction alters the hypothalamic-pituitary-adrenal response to stress

    Science.gov (United States)

    Meerlo, P.; Koehl, M.; van der Borght, K.; Turek, F. W.

    2002-01-01

    Chronic sleep restriction is an increasing problem in many countries and may have many, as yet unknown, consequences for health and well being. Studies in both humans and rats suggest that sleep deprivation may activate the hypothalamic-pituitary-adrenal (HPA) axis, one of the main neuroendocrine stress systems. However, few attempts have been made to examine how sleep loss affects the HPA axis response to subsequent stressors. Furthermore, most studies applied short-lasting total sleep deprivation and not restriction of sleep over a longer period of time, as often occurs in human society. Using the rat as our model species, we investigated: (i) the HPA axis activity during and after sleep deprivation and (ii) the effect of sleep loss on the subsequent HPA response to a novel stressor. In one experiment, rats were subjected to 48 h of sleep deprivation by placing them in slowly rotating wheels. Control rats were placed in nonrotating wheels. In a second experiment, rats were subjected to an 8-day sleep restriction protocol allowing 4 h of sleep each day. To test the effects of sleep loss on subsequent stress reactivity, rats were subjected to a 30-min restraint stress. Blood samples were taken at several time points and analysed for adrenocorticotropic hormone (ACTH) and corticosterone. The results show that ACTH and corticosterone concentrations were elevated during sleep deprivation but returned to baseline within 4 h of recovery. After 1 day of sleep restriction, the ACTH and corticosterone response to restraint stress did not differ between control and sleep deprived rats. However, after 48 h of total sleep deprivation and after 8 days of restricted sleep, the ACTH response to restraint was significantly reduced whereas the corticosterone response was unaffected. These results show that sleep loss not only is a mild activator of the HPA axis itself, but also affects the subsequent response to stress. Alterations in HPA axis regulation may gradually appear under

  10. Emotional labour and stress within mental health nursing.

    Science.gov (United States)

    Mann, S; Cowburn, J

    2005-04-01

    For many within the nursing profession, the work role involves a great deal of emotional work or 'emotional labour'. Such emotional work can be performed through 'surface acting' in which the individual simply feigns an appropriate emotion, or through 'deep acting' in which they actually try to feel the required emotion. The current study aims to aid understanding of the complex relationship between components of emotional labour and stress within the mental health nursing sector. Thirty-five mental health nurses completed questionnaires relating to a total of 122 nurse-patient interactions. Data were collected in relation to: (1) the duration and intensity of the interaction; (2) the variety of emotions expressed; (3) the degree of surface or deep acting the nurse performed; and (4) the perceived level of stress the interaction involved. Nurses also completed Daily Stress Indicators. Results suggest that: (1) emotional labour is positively correlated with both 'interaction stress' and daily stress levels; (2) the deeper the intensity of interactions and the more variety of emotions experienced, the more emotional labour was reported; and (3) surface acting was a more important predictor of emotional labour than deep acting. Implications for mental health nurses are outlined.

  11. Examining the stress-burnout relationship: the mediating role of negative thoughts.

    Science.gov (United States)

    Chang, Ko-Hsin; Lu, Frank J H; Chyi, Theresa; Hsu, Ya-Wen; Chan, Shi-Wei; Wang, Erica T W

    2017-01-01

    Using Smith's (1986) cognitive-affective model of athletic burnout as a guiding framework, the purpose of this study was to examine the relationships among athletes' stress in life, negative thoughts, and the mediating role of negative thoughts on the stress-burnout relationship. A total of 300 college student-athletes (males = 174; females = 126, M age  = 20.43 y, SD = 1.68) completed the College Student Athlete's Life Stress Scale (CSALSS; Lu et al., 2012), the Automatic Thoughts Questionnaire (ATQ; Hollon & Kendall, 1980), and the Athlete Burnout Questionnaire (ABQ; Raedeke & Smith, 2001). Correlational analyses found that two types of life stress and four types of negative thoughts correlated with burnout. Additionally, hierarchical regression analyses found that four types of negative thoughts partially mediated the stress-burnout relationship. We concluded that an athlete's negative thoughts play a pivotal role in predicting athletes' stress-burnout relationship. Future study may examine how irrational cognition influences athletes' motivation and psychological well-being.

  12. Examining the stress-burnout relationship: the mediating role of negative thoughts

    Science.gov (United States)

    Chyi, Theresa; Hsu, Ya-Wen; Chan, Shi-Wei; Wang, Erica T.W.

    2017-01-01

    Background Using Smith’s (1986) cognitive-affective model of athletic burnout as a guiding framework, the purpose of this study was to examine the relationships among athletes’ stress in life, negative thoughts, and the mediating role of negative thoughts on the stress-burnout relationship. Methods A total of 300 college student-athletes (males = 174; females = 126, Mage = 20.43 y, SD = 1.68) completed the College Student Athlete’s Life Stress Scale (CSALSS; Lu et al., 2012), the Automatic Thoughts Questionnaire (ATQ; Hollon & Kendall, 1980), and the Athlete Burnout Questionnaire (ABQ; Raedeke & Smith, 2001). Results Correlational analyses found that two types of life stress and four types of negative thoughts correlated with burnout. Additionally, hierarchical regression analyses found that four types of negative thoughts partially mediated the stress-burnout relationship. Discussion We concluded that an athlete’s negative thoughts play a pivotal role in predicting athletes’ stress-burnout relationship. Future study may examine how irrational cognition influences athletes’ motivation and psychological well-being. PMID:29302397

  13. The Role of Stress and Spirituality in Adolescent Substance Use.

    Science.gov (United States)

    Debnam, Katrina; Milam, Adam J; Furr-Holden, C Debra; Bradshaw, Catherine

    2016-05-11

    Substance use can occur as a result of coping with stress. Within the school context, youth are exposed to stressors related to school achievement and peer-relationships. Protective factors, such as spirituality, may moderate adolescents' engagement in substance use. The current study investigated the role of spirituality in the association between stress and substance use, in an effort to test the hypothesis that spirituality moderates the association between stress and substance use. This study used data from youth in grades 6-8 attending 40 parochial private schools. A total of 5,217 students participated in the web-based survey administered in Spring 2013. Multilevel structural equation models were used to examine the association between stress, spirituality, and substance use, while accounting for the nested nature of the data (i.e., students within schools). Higher stress was significantly associated with increased alcohol, tobacco, and other drug use among youth (b =.306, p stress and substance use. Implications for increasing students' adaptive coping when confronted with school-related stressors and the role of school climate are discussed.

  14. Alleviation of Water Stress Effects on MR220 Rice by Application of Periodical Water Stress and Potassium Fertilization

    Directory of Open Access Journals (Sweden)

    Nurul Amalina Mohd Zain

    2014-02-01

    Full Text Available The use of periodical water stress and potassium fertilization may enhance rice tolerance to drought stress and improve the crop’s instantaneous water use efficiency without much yield reduction. This study was conducted to assess the effects of different periodical water stress combined with potassium fertilization regimes on growth, yield, leaf gas exchanges and biochemical changes in rice grown in pots and compare them with standard local rice grower practices. Five treatments including (1 standard local grower’s practice (control, 80CF = 80 kg K2O/ha + control flooding; (2 120PW15 = 120 kg K2O/ha + periodical water stress for 15 days; (3 120DS15V = 120 kg K2O/ha + drought stress for 15 days during the vegetative stage; (4 120DS25V = 120 kg K2O/ha + drought stress for 25 days and (5 120DS15R = 120 kg K2O/ha + drought stress for 15 days during the reproductive stage, were evaluated in this experiment. Control and 120PW15 treatments were stopped at 100 DAS, and continuously saturated conditions were applied until harvest. It was found that rice under 120PW15 treatment showed tolerance to drought stress evidenced by increased water use efficiency, peroxidase (POX, catalase (CAT and proline levels, maximum efficiency of photosystem II (fv/fm and lower minimal fluorescence (fo, compared to other treatments. Path coefficient analysis revealed that most of parameters contribute directly rather than indirectly to rice yield. In this experiment, there were four factors that are directly involved with rice yield: grain soluble sugar, photosynthesis, water use efficiency and total chlorophyll content. The residual factors affecting rice yield are observed to be quite low in the experiment (0.350, confirming that rice yield was mostly influenced by the parameters measured during the study.

  15. The effects of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients: 6-month follow-up.

    Science.gov (United States)

    Carlson, L E; Ursuliak, Z; Goodey, E; Angen, M; Speca, M

    2001-03-01

    The goals of this work were to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients immediately after and 6 months after program completion. A convenience sample of eligible cancer patients were enrolled after they had given informed consent. All patients completed the Profile of Mood States (POMS) and Symptoms of Stress Inventory (SOSI) both before and after the intervention and 6 months later. The intervention consisted of a mindfulness meditation group lasting 1.5 h each week for 7 weeks, plus daily home meditation practice. A total of 89 patients, average age 51, provided pre-intervention data. Eighty patients provided post-intervention data, and 54 completed the 6-month follow-up The participants were heterogeneous with respect to type and stage of cancer. Patients' scores decreased significantly from before to after the intervention on the POMS and SOSI total scores and most subscales, indicating less mood disturbance and fewer symptoms of stress, and these improvements were maintained at the 6-month follow-up. More advanced stages of cancer were associated with less initial mood disturbance, while more home practice and higher initial POMS scores predicted improvements on the POMS between the pre- and post-intervention scores. Female gender and more education were associated with higher initial SOSI scores, and improvements on the SOSI were predicted by more education and greater initial mood disturbance. This program was effective in decreasing mood disturbance and stress symptoms for up to 6 months in both male and female patients with a wide variety of cancer diagnoses, stages of illness, and educational background, and with disparate ages.

  16. 78 FR 59791 - Annual Company-Run Stress Tests at Banking Organizations With Total Consolidated Assets of More...

    Science.gov (United States)

    2013-09-30

    ... bank on its Consolidated Financial Statements for Bank Holding Companies (FR Y-9C) or Consolidated... companies with $50 billion or more in total consolidated assets and any non-bank financial companies... with total consolidated assets of $50 billion or more and nonbank financial companies supervised by the...

  17. Electroconvulsive Stimulation, but not Chronic Restraint Stress, Causes Structural Alterations in Adult Rat Hippocampus

    DEFF Research Database (Denmark)

    Olesen, Mikkel V.; Wörtwein, Gitta; Pakkenberg, Bente

    2015-01-01

    The neurobiological mechanisms underlying depression are not fully understood. Only a few previous studies have used validated stereological methods to test how stress and animal paradigms of depression affect adult hippocampal neurogenesis and whether antidepressant therapy can counteract possible...... changes in an animal model. Thus, in this study we applied methods that are state of the art in regard to stereological cell counting methods. Using a validated rat model of depression in combination with a clinically relevant schedule of electroconvulsive stimulation, we estimated the total number...... of newly formed neurons in the hippocampal subgranular zone. Also estimated were the total number of neurons and the volume of the granule cell layer in adult rats subjected to chronic restraint stress and electroconvulsive stimulation either alone or in combination. We found that chronic restraint stress...

  18. Stress

    Science.gov (United States)

    ... can be life-saving. But chronic stress can cause both physical and mental harm. There are at least three different types of stress: Routine stress related to the pressures of work, family, and other daily responsibilities Stress brought about ...

  19. Effect of moxifloxacin on oxidative stress, paraoxonase-1 (PON1 ...

    African Journals Online (AJOL)

    oxidative stress in patients with multiple drug-resistant tuberculosis (MDR-TB). Methods: A total ofof ... seriously affects the quality of life and prognosis. [6]. ... balance between pro-oxidants and antioxidant ..... original work is properly credited.

  20. Mental stress: Neurophysiology and its regulation by Sudarshan Kriya Yoga

    Directory of Open Access Journals (Sweden)

    Sushil Chandra

    2017-01-01

    Full Text Available Aim: The present study focuses on analyzing the effects of Sudarshan Kriya yoga (SKY on EEG as well as ECG signals for stress regulation. To envision the regulation of stress Determination Test (DT has been used. We have chosen a control group for contriving a cogent comparison that could be corroborated using statistical tests. Subjects and Methods: A total of 20 subjects were taken in the study, of which 10 were allotted to a control group. Electroencephalograph was taken during a DT task, before and after SKY the sky session with 30 days of SKY session given to the experimental group. No SKY was given to the control group. Results: We quantified mental stress using EEG, ECG and DT synergistically and used SKY to regulate it. We observed that alpha band power decreases in the frontal lobe of the brain with increasing mental stress while frontal brain asymmetry decreases with increasing stress tolerance. Conclusions: These EEG, ECG and DT shows a significant decrement in mental stress and improvement in cognitive performance after SKY, indicating SKY as a good alternative of medication for stress management.