WorldWideScience

Sample records for tool failure monitoring

  1. Tools for in service monitoring and testing of riser to prevent failure and extend service life

    Energy Technology Data Exchange (ETDEWEB)

    Ward, Haakon; Bondevik, Jon Olav; Skjerve, Haavard; Tveit, Oeyvind [SeaFlex AS, Asker (Norway)

    2005-07-01

    Exploration and development of new oil and gas fields is heavily dependant on use of flexible pipes and many field developments would not have been possible without them. The number of flexible risers in service is constantly increasing since relatively few offshore projects have reached the estimated operational life and the operational lifetime of several fields in-service has been extended due to new and improved technology. Many risers have been in service over a large number of years. Some risers have been operated under demanding conditions such as severe dynamic loads, high pressure and temperatures. One may in some cases find that risers actually have shorter service life than estimated in the design phase due to the severe operational conditions. In order to extend the use of the riser, some risers may have to be modified and re-terminated and prepared for a new and less demanding application. In order to operate risers safely, it is important to re-assess the fatigue life in order to prevent potential riser failure. The operator should implement methods and tools for in-service monitoring and testing. This paper addresses efficient and reliable methods and tools for monitoring of critical operational parameters as well as in-service riser testing. A brief description of structural failure modes will also be given in order to understand how to interpret test results in view of potential failure modes. (author)

  2. Heart failure - home monitoring

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000113.htm Heart failure - home monitoring To use the sharing features on this page, please enable JavaScript. Heart failure is a condition in which the heart is ...

  3. VDC Monitoring Tools

    CERN Document Server

    Porat, Itay Gershon

    2017-01-01

    Electron drift velocity is an important parameter for muon path reconstruction capabilities of CMS drift tube chambers. The parameter is monitored independently by six dedicated drift velocity chambers (VDC). This report presents monitoring tools developed to study key VDC parameters such as anode voltage and current, as well as gas source. These graphical tools can be used to learn about VDC operation and performance, and contribute to understanding anode wire aging in the systems.

  4. Remote monitoring of heart failure: benefits for therapeutic decision making.

    Science.gov (United States)

    Martirosyan, Mihran; Caliskan, Kadir; Theuns, Dominic A M J; Szili-Torok, Tamas

    2017-07-01

    Chronic heart failure is a cardiovascular disorder with high prevalence and incidence worldwide. The course of heart failure is characterized by periods of stability and instability. Decompensation of heart failure is associated with frequent and prolonged hospitalizations and it worsens the prognosis for the disease and increases cardiovascular mortality among affected patients. It is therefore important to monitor these patients carefully to reveal changes in their condition. Remote monitoring has been designed to facilitate an early detection of adverse events and to minimize regular follow-up visits for heart failure patients. Several new devices have been developed and introduced to the daily practice of cardiology departments worldwide. Areas covered: Currently, special tools and techniques are available to perform remote monitoring. Concurrently there are a number of modern cardiac implantable electronic devices that incorporate a remote monitoring function. All the techniques that have a remote monitoring function are discussed in this paper in detail. All the major studies on this subject have been selected for review of the recent data on remote monitoring of HF patients and demonstrate the role of remote monitoring in the therapeutic decision making for heart failure patients. Expert commentary: Remote monitoring represents a novel intensified follow-up strategy of heart failure management. Overall, theoretically, remote monitoring may play a crucial role in the early detection of heart failure progression and may improve the outcome of patients.

  5. Individualized Behavioral Health Monitoring Tool

    Science.gov (United States)

    Mollicone, Daniel

    2015-01-01

    Behavioral health risks during long-duration space exploration missions are among the most difficult to predict, detect, and mitigate. Given the anticipated extended duration of future missions and their isolated, extreme, and confined environments, there is the possibility that behavior conditions and mental disorders will develop among astronaut crew. Pulsar Informatics, Inc., has developed a health monitoring tool that provides a means to detect and address behavioral disorders and mental conditions at an early stage. The tool integrates all available behavioral measures collected during a mission to identify possible health indicator warning signs within the context of quantitatively tracked mission stressors. It is unobtrusive and requires minimal crew time and effort to train and utilize. The monitoring tool can be deployed in space analog environments for validation testing and ultimate deployment in long-duration space exploration missions.

  6. Accurate Prediction of Motor Failures by Application of Multi CBM Tools: A Case Study

    Science.gov (United States)

    Dutta, Rana; Singh, Veerendra Pratap; Dwivedi, Jai Prakash

    2018-02-01

    Motor failures are very difficult to predict accurately with a single condition-monitoring tool as both electrical and the mechanical systems are closely related. Electrical problem, like phase unbalance, stator winding insulation failures can, at times, lead to vibration problem and at the same time mechanical failures like bearing failure, leads to rotor eccentricity. In this case study of a 550 kW blower motor it has been shown that a rotor bar crack was detected by current signature analysis and vibration monitoring confirmed the same. In later months in a similar motor vibration monitoring predicted bearing failure and current signature analysis confirmed the same. In both the cases, after dismantling the motor, the predictions were found to be accurate. In this paper we will be discussing the accurate predictions of motor failures through use of multi condition monitoring tools with two case studies.

  7. FFI: A software tool for ecological monitoring

    Science.gov (United States)

    Duncan C. Lutes; Nathan C. Benson; MaryBeth Keifer; John F. Caratti; S. Austin Streetman

    2009-01-01

    A new monitoring tool called FFI (FEAT/FIREMON Integrated) has been developed to assist managers with collection, storage and analysis of ecological information. The tool was developed through the complementary integration of two fire effects monitoring systems commonly used in the United States: FIREMON and the Fire Ecology Assessment Tool. FFI provides software...

  8. The Borg scale as an important tool of self-monitoring and self-regulation of exercise prescription in heart failure patients during hydrotherapy. A randomized blinded controlled trial.

    Science.gov (United States)

    Carvalho, Vitor Oliveira; Bocchi, Edimar Alcides; Guimarães, Guilherme Veiga

    2009-10-01

    The Borg Scale may be a useful tool for heart failure patients to self-monitor and self-regulate exercise on land or in water (hydrotherapy) by maintaining the heart rate (HR) between the anaerobic threshold and respiratory compensation point. Patients performed a cardiopulmonary exercise test to determine their anaerobic threshold/respiratory compensation points. The percentage of the mean HR during the exercise session in relation to the anaerobic threshold HR (%EHR-AT), in relation to the respiratory compensation point (%EHR-RCP), in relation to the peak HR by the exercise test (%EHR-Peak) and in relation to the maximum predicted HR (%EHR-Predicted) was calculated. Next, patients were randomized into the land or water exercise group. One blinded investigator instructed the patients in each group to exercise at a level between "relatively easy and slightly tiring". The mean HR throughout the 30-min exercise session was recorded. The %EHR-AT and %EHR-predicted did not differ between the land and water exercise groups, but they differed in the %EHR-RCP (95 +/-7 to 86 +/-7, P<0.001) and in the %EHR-Peak (85 +/-8 to 78 +/-9, P=0.007). Exercise guided by the Borg scale maintains the patient's HR between the anaerobic threshold and respiratory compensation point (ie, in the exercise training zone).

  9. STUDIES ON TOOL WEAR CONDITION MONITORING

    Directory of Open Access Journals (Sweden)

    Hüseyin Metin ERTUNÇ

    2001-01-01

    Full Text Available In this study, wear mechanisms on cutting tools, especially for the drill bits, during the cutting operation have been investigated. As the importance of full automation in industry has gained substantial importance, tool wear condition monitoring during the cutting operation has been the subject of many investigators. Tool condition monitoring is very crucial in order to change the tool before breakage. Because tool breakage can cause considerable economical damage to both the machine tool and workpiece. In this paper, the studies on the monitoring of drill bit wear in literature have been introduced; the direct/indirect techniques used and sensor fusion techniques have been summarized. The methods which were proposed to determine tool wear evolution as processing the sensor signals collected have been provided and their references have been given for detailed information.

  10. Internet optical infrastructure issues on monitoring and failure restoration

    CERN Document Server

    Tapolcai, János; Babarczi, Péter; Rónyai, Lajos

    2015-01-01

    This book covers the issues of monitoring, failure localization, and restoration in the Internet optical backbone, and focuses on the progress of state-of-the-art in both industry standard and academic research. The authors summarize, categorize, and analyze the developed technology in the context of Internet fault management and failure recovery under the Generalized Multi-Protocol Label Switching (GMPLS), via both aspects of network operations and theories. Examines monitoring, failure localization, and failure restoration in the Internet backbone Includes problem formulations based on combinatorial group testing and topology coding Covers state-of-the-art development for the Internet backbone fault management and failure recovery

  11. Failure Modes and Effects Analysis (FMEA) Assistant Tool

    Data.gov (United States)

    National Aeronautics and Space Administration — The FMEA Assistant tool offers a new and unique approach to assist hardware developers and safety analysts perform failure analysis by using model based systems...

  12. Failure Modes and Effects Analysis (FMEA) Assistant Tool Feasibility Study

    Science.gov (United States)

    Flores, Melissa; Malin, Jane T.

    2013-01-01

    An effort to determine the feasibility of a software tool to assist in Failure Modes and Effects Analysis (FMEA) has been completed. This new and unique approach to FMEA uses model based systems engineering concepts to recommend failure modes, causes, and effects to the user after they have made several selections from pick lists about a component s functions and inputs/outputs. Recommendations are made based on a library using common failure modes identified over the course of several major human spaceflight programs. However, the tool could be adapted for use in a wide range of applications from NASA to the energy industry.

  13. Fatigue Monitoring Tool for Airline Operators (FMT

    Directory of Open Access Journals (Sweden)

    Gislason Sigurdur Hrafn

    2017-12-01

    Full Text Available A Fatigue Monitoring Tool (FMT model was constructed for an operational airline in order to manage the fatigue levels of their crews in accordance with Fatigue Risk Management System (FRMS practices. This article describes the implementation of the Fatigue Monitoring Tool model and the airline’s aims to put the recent scientific findings on aviation fatigue into practical use. The model consists of proxy points allotted to various duties and rest periods.

  14. Web Defacement and Intrusion Monitoring Tool: WDIMT

    CSIR Research Space (South Africa)

    Masango, Mfundo G

    2017-09-01

    Full Text Available at altering the content of the web pages or to make the website inactive. This paper proposes a Web Defacement and Intrusion Monitoring Tool, that could be a possible solution to the rapid identification of altered or deleted web pages. The proposed tool...

  15. Failures of tool steels after heat treatments

    International Nuclear Information System (INIS)

    Nunez-Gonzalez, G.

    1990-01-01

    The main objective of the work was to determine the most common defects occuring in tool steels of the AISI D-2, S-1, 0-1 and W-2 series during thermal treatment. Defects were evaluated by metallographic analyses, a method used to determine and recognize micro structural defects and their origin in order to be able to eliminate and correct some of the stages that are caused by heat treatment. Results show a large number of defects due to irregularities during thermal heating such as excess or lack of temperature, heating time, and atmosphere, rectifying and handling in service and, to a lesser extent, poor design. In conclusion, with the results obtained for each of the thermal treatments it is necessary to define, particularly the values each of these variables should have since they affect the material properties. (Author)

  16. Researches regarding cutting tool condition monitoring

    Directory of Open Access Journals (Sweden)

    Inţă Marinela

    2017-01-01

    Full Text Available The paper main purpose is monitoring of tool wear in metal cutting using neural networks due to their ability of learning and adapting their self, based on experiments. Monitoring the cutting process is difficult to perform on-line because of the complexity of tool wear process, which is the most important parameter that defines the tool state at a certain moment. Most of the researches appraise the tool wear by indirect factors such as forces, consumed power, vibrations or the surface quality. In this case, it is important to combine many factors for increasing the accuracy of tool wear prediction and establish the admissible size of wear. For this, paper both the theoretical data obtained from FEM analyze and experimental ones are used and compared in order to appreciate the reliability of the results.

  17. Skin Examination: An Important Diagnostic Tool in Renal Failure Patients.

    Science.gov (United States)

    Van de Velde-Kossmann, Karen M

    2018-01-26

    Renal failure is common in the United States with an estimated prevalence of 660,000 treated end-stage renal disease patients in 2015 [1]. Causes of renal failure are many, and complications from renal failure, underlying disease, and treatment are not infrequent. Examples of common skin manifestations include xerosis, pigmentary change, and nail dystrophies. Frequent disease-specific skin changes may be helpful in the diagnosis of primary disorders leading to renal disease or severity of disease including bullosis diabeticorum, sclerodactyly, or leukoctoclastic vasculitis. Some cutaneous changes, such as the multiple angiokeratomas of Fabry disease or the plexiform neurofibromas of neurofibromatosis, are pathognomonic of genetic disorders, which often lead to renal failure. Careful examination of the skin can provide crucial clues to diagnosis of renal failure causation and aid in monitoring complications. © 2018 S. Karger AG, Basel.

  18. Triplexer Monitor Design for Failure Detection in FTTH System

    Science.gov (United States)

    Fu, Minglei; Le, Zichun; Hu, Jinhua; Fei, Xia

    2012-09-01

    Triplexer was one of the key components in FTTH systems, which employed an analog overlay channel for video broadcasting in addition to bidirectional digital transmission. To enhance the survivability of triplexer as well as the robustness of FTTH system, a multi-ports device named triplexer monitor was designed and realized, by which failures at triplexer ports can be detected and localized. Triplexer monitor was composed of integrated circuits and its four input ports were connected with the beam splitter whose power division ratio was 95∶5. By means of detecting the sampled optical signal from the beam splitters, triplexer monitor tracked the status of the four ports in triplexer (e.g. 1310 nm, 1490 nm, 1550 nm and com ports). In this paper, the operation scenario of the triplexer monitor with external optical devices was addressed. And the integrated circuit structure of the triplexer monitor was also given. Furthermore, a failure localization algorithm was proposed, which based on the state transition diagram. In order to measure the failure detection and localization time under the circumstance of different failed ports, an experimental test-bed was built. Experiment results showed that the detection time for the failure at 1310 nm port by the triplexer monitor was less than 8.20 ms. For the failure at 1490 nm or 1550 nm port it was less than 8.20 ms and for the failure at com port it was less than 7.20 ms.

  19. A Tool for Preventing Teamwork Failure: the TFP Questionnaire

    DEFF Research Database (Denmark)

    Qvist, Palle; Rebollar, Rubeén; Lidón, Iván

    2010-01-01

    This paper presents the process used to devise the Teamwork Failure Prevention Questionnaire (TFP Questionnaire), a tool that allows teams with problems in functioning to be detected early. The TFP Questionnaire was formulated in a project management course at the University of Zaragoza (Spain...

  20. Electron microscopy--new tool for service failure study

    Energy Technology Data Exchange (ETDEWEB)

    Warke, W.R.; McCall, J.L.

    1965-05-01

    Electron microscopy, now well established as a research tool for the study of metal fractures, can be valuable for analyzing service failures. The high magnifications of electron microscopes, ranging from 500 to 200,000 X, coupled with their large vertical resolution, make it possible to distinguish overload failures from fatigue failures from brittle intergranular failures, and so on. Generally speaking, 2 basic techniques are used to replicate fractured surfaces. They the direct carbon method and the 2-stage plastic carbon technique. Each has its limitations and specific areas of application. Direct carbon eliminates an intermediate step; it thus gives a higher fidelity replica and allows extraction of inclusions and precipitates, but destroys the sample. The plastic carbon replica is nondestructive, but less faithful in reproducing the finest features of the surface. For this reason, the direct method is used primarily for fundamental research, while the plastic carbon technique is used when specimen availability is a problem or service failures are to be analyzed. The applicability of electron microscopy to service failure analyses is illustrated by 3 examples.

  1. Tools for Trigger Rate Monitoring at CMS

    CERN Document Server

    Smith, Geoffrey; Wightman, Andrew Steven

    2017-01-01

    In 2017, we expect the LHC to deliver an instantaneous luminosity of roughly $2.0 \\times 10^{34}$~cm$^{-2}$s$^{-1}$ to the Compact Muon Solenoid (CMS) experiment, with about 60 simultaneous proton-proton collisions (pileup) per event. In these challenging conditions, it is important to be able to intelligently monitor the rate at which data are being collected (the trigger rate). It is not enough to simply look at the trigger rate; it is equally important to compare the trigger rate with expectations. We present a set of software tools that have been developed to accomplish this. The tools include a real-time component - a script that monitors the rates of individual triggers during data-taking, and activates an alarm if rates deviate significantly from expectation. Fits are made to previously collected data and extrapolated to higher pileup. The behavior of triggers as a function of pileup is then monitored as data are collected - plots are automatically produced on an hourly basis and uploaded to a web area...

  2. Predicting Plan Failure by Monitoring Action Sequences and Duration

    Directory of Open Access Journals (Sweden)

    Giovani Parente FARIAS

    2017-07-01

    Full Text Available An agent can attempt to achieve multiple goals and each goal can be achieved by applying various different plans. Anticipating failures in agent plan execution is important to enable an agent to develop strategies to avoid or circumvent such failures, allowing the agent to achieve its goal. Plan recognition can be used to infer which plans are being executed from observations of sequences of activities being performed by an agent. Symbolic Plan Recognition is an algorithm that represents knowledge about the agents under observation in the form of a plan library. In this work, we use this symbolic algorithm to find out which plan the agent is performing and we develop a failure prediction system, based on information available in the plan library and in a simplified calendar which manages the goals the agent has to achieve. This failure predictor is able to monitor the sequence of agent actions and detects if an action is taking too long or does not match the plan that the agent was expected to be performing. We have successfully employed this approach in a health-care prototype system.

  3. A Remote Patient Monitoring System for Congestive Heart Failure

    Science.gov (United States)

    Suh, Myung-kyung; Chen, Chien-An; Woodbridge, Jonathan; Tu, Michael Kai; Kim, Jung In; Nahapetian, Ani; Evangelista, Lorraine S.; Sarrafzadeh, Majid

    2011-01-01

    Congestive heart failure (CHF) is a leading cause of death in the United States affecting approximately 670,000 individuals. Due to the prevalence of CHF related issues, it is prudent to seek out methodologies that would facilitate the prevention, monitoring, and treatment of heart disease on a daily basis. This paper describes WANDA (Weight and Activity with Blood Pressure Monitoring System); a study that leverages sensor technologies and wireless communications to monitor the health related measurements of patients with CHF. The WANDA system is a three-tier architecture consisting of sensors, web servers, and back-end databases. The system was developed in conjunction with the UCLA School of Nursing and the UCLA Wireless Health Institute to enable early detection of key clinical symptoms indicative of CHF-related decompensation. This study shows that CHF patients monitored by WANDA are less likely to have readings fall outside a healthy range. In addition, WANDA provides a useful feedback system for regulating readings of CHF patients. PMID:21611788

  4. Frequency Stability Monitoring Tool: A monitoring tool for the LHC bunch crossing signal

    CERN Document Server

    Hadjiantonis, Marios

    2013-01-01

    One of the basic responsibilities of the ATLAS Level 1 Central Trigger Processor is the distribution of timing signals, for example, the ∼ 40MHz bunch crossing signal from the accelerator, to the various parts of the detector. This is necessary in order to be able to synchronize the different signals coming from all the sub-detectors, so as to be able to reconstruct physical objects, and conduct correct measurements. For this reason, a monitoring tool has been developed, that is able to detect abnormatities in the bunch crossing or any other different timing signal.

  5. Real Time Fire Reconnaissance Satellite Monitoring System Failure Model

    Science.gov (United States)

    Nino Prieto, Omar Ariosto; Colmenares Guillen, Luis Enrique

    2013-09-01

    In this paper the Real Time Fire Reconnaissance Satellite Monitoring System is presented. This architecture is a legacy of the Detection System for Real-Time Physical Variables which is undergoing a patent process in Mexico. The methodologies for this design are the Structured Analysis for Real Time (SA- RT) [8], and the software is carried out by LACATRE (Langage d'aide à la Conception d'Application multitâche Temps Réel) [9,10] Real Time formal language. The system failures model is analyzed and the proposal is based on the formal language for the design of critical systems and Risk Assessment; AltaRica. This formal architecture uses satellites as input sensors and it was adapted from the original model which is a design pattern for physical variation detection in Real Time. The original design, whose task is to monitor events such as natural disasters and health related applications, or actual sickness monitoring and prevention, as the Real Time Diabetes Monitoring System, among others. Some related work has been presented on the Mexican Space Agency (AEM) Creation and Consultation Forums (2010-2011), and throughout the International Mexican Aerospace Science and Technology Society (SOMECYTA) international congress held in San Luis Potosí, México (2012). This Architecture will allow a Real Time Fire Satellite Monitoring, which will reduce the damage and danger caused by fires which consumes the forests and tropical forests of Mexico. This new proposal, permits having a new system that impacts on disaster prevention, by combining national and international technologies and cooperation for the benefit of humankind.

  6. Perspectives on Wellness Self-Monitoring Tools for Older Adults

    Science.gov (United States)

    Huh, Jina; Le, Thai; Reeder, Blaine; Thompson, Hilaire J.; Demiris, George

    2013-01-01

    Purpose Our purpose was to understand different stakeholder perceptions about the use of self-monitoring tools, specifically in the area of older adults’ personal wellness. In conjunction with the advent of personal health records, tracking personal health using self-monitoring technologies shows promising patient support opportunities. While clinicians’ tools for monitoring of older adults have been explored, we know little about how older adults may self-monitor their wellness and health and how their health care providers would perceive such use. Methods We conducted three focus groups with health care providers (n=10) and four focus groups with community-dwelling older adults (n=31). Results Older adult participants’ found the concept of self-monitoring unfamiliar and this influenced a narrowed interest in the use of wellness self-monitoring tools. On the other hand, health care provider participants showed open attitudes towards wellness monitoring tools for older adults and brainstormed about various stakeholders’ use cases. The two participant groups showed diverging perceptions in terms of: perceived uses, stakeholder interests, information ownership and control, and sharing of wellness monitoring tools. Conclusions Our paper provides implications and solutions for how older adults’ wellness self-monitoring tools can enhance patient-health care provider interaction, patient education, and improvement in overall wellness. PMID:24041452

  7. Individual monitoring: A tool for active ALARA

    International Nuclear Information System (INIS)

    Hoefert, M.

    1989-01-01

    The system of individual monitoring at CERN is presented. Following the substantial decrease of individual doses over the last decade, emphasis is now placed on monitoring rather than on dosimetric aspects. Future developments have to face a possible decrease of dose limits that are difficult to control in view of the lower detection limits for the detectors presently used. One possible solution to the problem is the increase in the wearing time for individual dosemeters. (author)

  8. Heart failure patients utilizing an electric home monitor: What effects does heart failure have on their quality of life?

    Science.gov (United States)

    Simuel, Gloria J.

    Heart Failure continues to be a major public health problem associated with high mortality and morbidity. Heart Failure is the leading cause of hospitalization for persons older than 65 years, has a poor prognosis and is associated with poor quality of life. More than 5.3 million American adults are living with heart failure. Despite maximum medical therapy and frequent hospitalizations to stabilize their condition, one in five heart failure patients die within the first year of diagnosis. Several disease-management programs have been proposed and tested to improve the quality of heart failure care. Studies have shown that hospital admissions and emergency room visits decrease with increased nursing interventions in the home and community setting. An alternative strategy for promoting self-management of heart failure is the use of electronic home monitoring. The purpose of this study was to examine what effects heart failure has on patient's quality of life that had been monitoring on an electronic home monitor longer than 2 months. Twenty-one questionnaires were given to patients utilizing an electronic home monitor by their home health agency nurse. Eleven patients completed the questionnaire. The findings showed that there is some deterioration in quality of life with more association with the physical aspects of life than with the emotional aspects of life, which probably was due to the small sample size. There was no significant difference in readmission rates in patients utilizing an electronic home monitor. Further research is needed with a larger population of patients with chronic heart failure and other chronic diseases which may provide more data, and address issues such as patient compliance with self-care, impact of heart failure on patient's quality of life, functional capacity, and heart failure patient's utilization of the emergency rooms and hospital. Telemonitoring holds promise for improving the self-care abilities of persons with HF.

  9. New tools for monitoring biodiversity and environments

    OpenAIRE

    Baker, Edward

    2014-01-01

    How do we do science when the computer of 15 years ago now fits in your pocket and costs less than the battery you need to run it? Should biodiversity scientists work with the hacker and maker community? Should we forge links with engineering departments? Should hardware become a standard tool of the biodiversity informatician?

  10. Multi-Modal Neurodiagnostic Tool for Stress Monitoring, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has a requirement for a neurodiagnostic tool that can be used to monitor the behavioral health of the crew during long duration Exploration missions. The device...

  11. Remote Monitoring for Chronic Disease Management: Atrial Fibrillation and Heart Failure.

    Science.gov (United States)

    Ono, Maki; Varma, Niraj

    2018-03-01

    This review aims to cover the latest evidence of remote monitoring of cardiac implantable electronic devices for the management of atrial fibrillation and heart failure. Remote monitoring is useful for early detection for device-detected atrial fibrillation, which increases the risk of thromboembolic events. Early anticoagulation based on remote monitoring potentially reduces the risk of stroke, but optimal alert setting needs to be clarified. Multiparameter monitoring with automatic transmission is useful for heart failure management. Improved adherence to remote monitoring and an optimal algorithm for transmitted alerts and their management are warranted in the management of heart failure. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Assessing the utilisation of a child health monitoring tool | Blaauw ...

    African Journals Online (AJOL)

    ... tool for growth monitoring and the assessment of health among children from birth to five years of age, was introduced in South Africa in February 2011. Objectives. The study assessed the implementation of growth monitoring and promotion, immunisation, vitamin A supplementation, and deworming sections of the RtHB.

  13. A model of tool wear monitoring system for turning

    OpenAIRE

    Šimunović, Goran; Ficko, Mirko; Šarić, Tomislav; Milošević, Mijodrag; Antić, Aco

    2015-01-01

    Acquiring high-quality and timely information on the tool wear condition in real time, presents a necessary prerequisite for identification of tool wear degree, which significantly improves the stability and quality of the machining process. Defined in this paper is a model of tool wear monitoring system with special emphasis on the module for acquisition and processing of vibration acceleration signal by applying discrete wavelet transformations (DWT) in signal decomposition. The paper prese...

  14. Life cycle strain monitoring in glass fibre reinforced polymer laminates using embedded fibre Bragg grating sensors from manufacturing to failure

    DEFF Research Database (Denmark)

    Nielsen, Michael Wenani; Schmidt, Jacob Wittrup; Høgh, Jacob Herold

    2013-01-01

    A holistic approach to strain monitoring in fibre-reinforced polymer composites is presented using embedded fibre Bragg grating sensors. Internal strains are monitored in unidirectional E-glass/epoxy laminate beams during vacuum infusion, curing, post-curing and subsequent loading in flexure unti...... Bragg gratings within the loading regime. This study confirms the effectiveness of composite life cycle strain monitoring for developing consistent manufacturing processes....... failure. The internal process-induced strain development is investigated through use of different cure schedules and tool/part interactions. The fibre Bragg grating sensors successfully monitor resin flow front progression during infusion, and strain development during curing, representative...... of the different cure temperatures and tool/part interfaces used. Substantial internal process-induced strains develop in the transverse fibre direction, which should be taken into consideration when designing fibre-reinforced polymer laminates. Flexure tests indicate no significant difference in the mechanical...

  15. A Tool for Monitoring of YouTube Content

    DEFF Research Database (Denmark)

    Lashari, Intzar Ali; Wiil, Uffe Kock

    2014-01-01

    The expansion in use of social media has been very significant in the past decade. It has become a topic of interest for many researchers to find the most connected people, the most influential people, etc. in social media for various purposes. However, collection and monitoring of data in abunda......The expansion in use of social media has been very significant in the past decade. It has become a topic of interest for many researchers to find the most connected people, the most influential people, etc. in social media for various purposes. However, collection and monitoring of data...... in abundance from social media is difficult. This paper describes a new tool that can collect, monitor, and mine data from YouTube. The tool is part of a larger framework aimed at monitoring various social media including Facebook, Twitter, and YouTube. A specific case focusing on “Islamic Jihad Holy War......” demonstrates the features of the tool....

  16. Virtual platforms use: a useful monitoring tool

    Directory of Open Access Journals (Sweden)

    Jerónimo Torres-Porras

    2018-03-01

    Full Text Available The European Higher Education Area is motivating a substantial change in university education and is promoting the use of new Technologies of Information and Communication. The educational virtual platform Moodle is one of the most widely used worldwide and also facilitates the creation of online learning sites and provides data of monitoring platform by users. This study focuses on the extent of use of Moodle by university students, following the same groups in their first and last academic year, finding a significant relation with the marks obtained in the subjects analyzed. This relationship shows that students with lower marks have used less Moodle platform, which has been maintained until the end of the Degree. Therefore, it is suggested that records in virtual platforms could be used as an index of interest in the subjects and it is recommended that they be analyzed during the first academic year in order to detect the least motivated groups and thus be able to act.

  17. Tools for automated acoustic monitoring within the R package monitoR

    Science.gov (United States)

    Katz, Jonathan; Hafner, Sasha D.; Donovan, Therese

    2016-01-01

    The R package monitoR contains tools for managing an acoustic-monitoring program including survey metadata, template creation and manipulation, automated detection and results management. These tools are scalable for use with small projects as well as larger long-term projects and those with expansive spatial extents. Here, we describe typical workflow when using the tools in monitoR. Typical workflow utilizes a generic sequence of functions, with the option for either binary point matching or spectrogram cross-correlation detectors.

  18. Perancangan Network Monitoring Tools Menggunakan Autonomous Agent Java

    Directory of Open Access Journals (Sweden)

    Khurniawan Eko S

    2016-08-01

    Full Text Available Tugas pengelolaan jaringan yang dilakukan administrator jaringan diantaranya yaitu pengumpulan informasi resource jaringan yang tersedia. Teknologi SNMP (Simple Network Management Protocol memberikan fleksibilitas bagi administrator jaringan dalam mengatur network secara keseluruhan dari satu lokasi. Aplikasi Network Monitoring Tools berbasis Agent JAVA terdiri dari Master agent yang bertugas untuk melakukan management Request agent serta akses database. Request agent yang bertugas untuk melakukan pemantauan server yang mengimplementasi library SNMP4j dengan sistem multi-agent. Disisi interface, aplikasi Network Monitoring Tools menggunakan media web sebagai interface administrator sehingga dapat digunakan darimana saja  dan kapan saja.  Hasil dari penelitian ini memperlihatkan bahwa aplikasi yang dibuat bekerja sebagai Network Monitoring Tools mampu bekerja dengan persen error pada kisaran 0-18%. Selain itu Aplikasi ini menghasilkan tren pembacaan data server lebih stabil dan cepat dibandingkan dengan aplikasi Cacti. Hal ini didukung oleh kemampuan Request Agent yang mampu merespon tingkat beban kerja server yang di pantau.

  19. Design principles of a web interface for monitoring tools

    International Nuclear Information System (INIS)

    Aiftimiei, C; Pra, S D; Fantinel, S; Andreozzi, S; Fattibene, E; Misurelli, G; Cuscela, G; Donvito, G; Dudhalkar, V; Maggi, G; Pierro, A

    2008-01-01

    A monitoring tool of a complex Grid system can gather a huge amount of information that have to be presented to the users in the most comprehensive way. Moreover different types of consumers could be interested in inspecting and analyzing different subsets of data. The main goal in designing a Web interface for the presentation of monitoring information is to organize the huge amount of data in a simple, user-friendly and usable structure. One more problem is to consider different approaches, skills and interests that all the possible categories of users have in looking for the desired information. Starting from the Information Architecture guidelines for the Web, it is possible to design Web interfaces towards a closer user experience and to deal with an advanced user interaction through the implementation of many Web standard technologies. In this paper, we will present a number of principles for the design of Web interface for monitoring tools that provide a wider, richer range of possibilities for what concerns the user interaction. These principles are based on an extensive review of the current literature in Web design and on the experience with the development of the GridICE monitoring tool. The described principles can drive the evolution of the Web interface of Grid monitoring tools

  20. Frequency and failure of high-resolution monitors in a filmless imaging department

    Science.gov (United States)

    Siegel, Eliot L.; Reiner, Bruce I.; Cadogan, Michael

    1999-07-01

    The purpose of this study was to assess the rate of failure of the high resolution monitors used for primary diagnosis in a filmless radiology department and to analyze the type of problems encountered as well as the action taken to report the monitors. Data were collected from PACS service logs to determine rates of monitor adjustment and replacement, the symptoms reported, and the action taken. Analysis of monitor service records demonstrated a high rate of monitor replacement resulting in a relatively short 'life expectancy of 2.4 years. The result of this study support our subjective impression and those of other colleagues in the PACS community of an unacceptably high monitor failure rate with 2,000 pixel monitors used for primary diagnosis. Requests for proposals for PACS and service contracts must carefully specify requirements for monitor images quality and conditions under which the vendor is required to replace these monitors.

  1. Renal function monitoring in heart failure – what is the optimal frequency? A narrative review

    Science.gov (United States)

    Wright, David; Devonald, Mark Alexander John; Pirmohamed, Munir

    2017-01-01

    The second most common cause of hospitalization due to adverse drug reactions in the UK is renal dysfunction due to diuretics, particularly in patients with heart failure, where diuretic therapy is a mainstay of treatment regimens. Therefore, the optimal frequency for monitoring renal function in these patients is an important consideration for preventing renal failure and hospitalization. This review looks at the current evidence for optimal monitoring practices of renal function in patients with heart failure according to national and international guidelines on the management of heart failure (AHA/NICE/ESC/SIGN). Current guidance of renal function monitoring is in large part based on expert opinion, with a lack of clinical studies that have specifically evaluated the optimal frequency of renal function monitoring in patients with heart failure. Furthermore, there is variability between guidelines, and recommendations are typically nonspecific. Safer prescribing of diuretics in combination with other antiheart failure treatments requires better evidence for frequency of renal function monitoring. We suggest developing more personalized monitoring rather than from the current medication‐based guidance. Such flexible clinical guidelines could be implemented using intelligent clinical decision support systems. Personalized renal function monitoring would be more effective in preventing renal decline, rather than reacting to it. PMID:28901643

  2. Renal function monitoring in heart failure - what is the optimal frequency? A narrative review.

    Science.gov (United States)

    Al-Naher, Ahmed; Wright, David; Devonald, Mark Alexander John; Pirmohamed, Munir

    2018-01-01

    The second most common cause of hospitalization due to adverse drug reactions in the UK is renal dysfunction due to diuretics, particularly in patients with heart failure, where diuretic therapy is a mainstay of treatment regimens. Therefore, the optimal frequency for monitoring renal function in these patients is an important consideration for preventing renal failure and hospitalization. This review looks at the current evidence for optimal monitoring practices of renal function in patients with heart failure according to national and international guidelines on the management of heart failure (AHA/NICE/ESC/SIGN). Current guidance of renal function monitoring is in large part based on expert opinion, with a lack of clinical studies that have specifically evaluated the optimal frequency of renal function monitoring in patients with heart failure. Furthermore, there is variability between guidelines, and recommendations are typically nonspecific. Safer prescribing of diuretics in combination with other antiheart failure treatments requires better evidence for frequency of renal function monitoring. We suggest developing more personalized monitoring rather than from the current medication-based guidance. Such flexible clinical guidelines could be implemented using intelligent clinical decision support systems. Personalized renal function monitoring would be more effective in preventing renal decline, rather than reacting to it. © 2017 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

  3. Identifying the cause of cutting tool failure by using simulation software

    Directory of Open Access Journals (Sweden)

    Zrak Andrej

    2018-01-01

    Full Text Available The article is focused on the construction problems of cutting tools designed for manufacturing components in high numbers. Analysis of the tool with low lifetime is provided with the use of simulation software to detect the causes of the tool failure. Parameters of the simulation are close to the real conditions of the tool in production. The results from the simulation indicate that the bending moment occurs in the tool because of forces which have opposite direction on different areas. On these basis technological adjustments are made. These adjustments are also analysed by using simulation software.

  4. Assessing the utilisation of a child health monitoring tool

    African Journals Online (AJOL)

    2017-12-06

    Dec 6, 2017 ... The Road-to-Health booklet (RtHB), a standardised national tool for growth monitoring and the assessment of health among children from birth to .... [8,9] Overweight and obesity were expressed as the proportion of individuals with weight-for-length/height Z-scores above 2 SD and 3 SD, respectively.[8,9].

  5. Intelligent Tool Condition Monitoring In High-Speed Turning Of ...

    African Journals Online (AJOL)

    In this paper, a Multi-Layered Perceptron (MLP) neural net-work model has been developed for on-line condition monitoring of tool wear in high-speed turning of Titanium-based alloy (Ti-6Al-4V). Machining trials were ... The neural network model was designed using Matlab® neural toolbox. Accuracy of model for the ...

  6. GNAM and OHP Monitoring Tools for ATLAS experiment at LHC.

    CERN Document Server

    Adragna, P; Della Pietra, M; Dotti, A; Ferrari, R; Gaudio, G; Roda, C; Salvatore, D; Vandelli, W; Zema, P F; 2006 Nuclear Science Symposium, Medical Imaging Conference and 15th International Room Temperature Semiconductor Detector Workshop

    2007-01-01

    ATLAS is one of the four experiments under construction along the Large Hadron Collider (LHC) ring at CERN. The LHC will produce interactions at a center-of-mass energy equal to √s = 14 TeV at 40 MHz rate. The detector consists of more than 140 million electronic channels. The challenging experimental environment and the extreme detector complexity impose the necessity of a common scalable distributed monitoring framework, which can be tuned for the optimal use by different ATLAS sub-detectors at the various levels of the ATLAS data flow. This note presents two monitoring tools that have been developed for this aim within the architecture ATLAS Monitoring Framework and the Data Acquisition System: GNAM and OHP. The first one is a framework for online histogram production; the second one is graphical application for histogram presentation. This tools are now widely used during the ATLAS commissioning and their performances are reported in this note

  7. Distributed monitoring for the prevention of cascading failures in operational power grids

    NARCIS (Netherlands)

    M.E. Warnier (Martijn); S.O. Dulman (Stefan); Y. Koç (Yakup); E.J. Pauwels (Eric)

    2017-01-01

    textabstractElectrical power grids are vulnerable to cascading failures that can lead to large blackouts. The detection and prevention of cascading failures in power grids are important problems. Currently, grid operators mainly monitor the states (loading levels) of individual components in a power

  8. Monitoring and remote failure detection of grid-connected PV systems based on satellite observations

    NARCIS (Netherlands)

    Drews, A.; de Keizer, A.C.; Beyer, H.G.; Lorenz, E.; Betcke, J.W.H.; van Sark, W.G.J.H.M.; Heydenreich, W.; Wiemken, E.; Stettler, S.; Toggweiler, P.; Bofinger, S.; Schneider, M.; Heilscher, G.; Heinemann, D.

    Small grid-connected photovoltaic systems up to 5 kWp are often not monitored because advanced surveillance systems are not economical. Hence, some system failures which lead to partial energy losses stay unnoticed for a long time. Even a failure that results in a larger energy deficit can be

  9. Enhanced methodology of focus control and monitoring on scanner tool

    Science.gov (United States)

    Chen, Yen-Jen; Kim, Young Ki; Hao, Xueli; Gomez, Juan-Manuel; Tian, Ye; Kamalizadeh, Ferhad; Hanson, Justin K.

    2017-03-01

    As the demand of the technology node shrinks from 14nm to 7nm, the reliability of tool monitoring techniques in advanced semiconductor fabs to achieve high yield and quality becomes more critical. Tool health monitoring methods involve periodic sampling of moderately processed test wafers to detect for particles, defects, and tool stability in order to ensure proper tool health. For lithography TWINSCAN scanner tools, the requirements for overlay stability and focus control are very strict. Current scanner tool health monitoring methods include running BaseLiner to ensure proper tool stability on a periodic basis. The focus measurement on YIELDSTAR by real-time or library-based reconstruction of critical dimensions (CD) and side wall angle (SWA) has been demonstrated as an accurate metrology input to the control loop. The high accuracy and repeatability of the YIELDSTAR focus measurement provides a common reference of scanner setup and user process. In order to further improve the metrology and matching performance, Diffraction Based Focus (DBF) metrology enabling accurate, fast, and non-destructive focus acquisition, has been successfully utilized for focus monitoring/control of TWINSCAN NXT immersion scanners. The optimal DBF target was determined to have minimized dose crosstalk, dynamic precision, set-get residual, and lens aberration sensitivity. By exploiting this new measurement target design, 80% improvement in tool-to-tool matching, >16% improvement in run-to-run mean focus stability, and >32% improvement in focus uniformity have been demonstrated compared to the previous BaseLiner methodology. Matching <2.4 nm across multiple NXT immersion scanners has been achieved with the new methodology of set baseline reference. This baseline technique, with either conventional BaseLiner low numerical aperture (NA=1.20) mode or advanced illumination high NA mode (NA=1.35), has also been evaluated to have consistent performance. This enhanced methodology of focus

  10. Thermal Analysis for Condition Monitoring of Machine Tool Spindles

    International Nuclear Information System (INIS)

    Clough, D; Fletcher, S; Longstaff, A P; Willoughby, P

    2012-01-01

    Decreasing tolerances on parts manufactured, or inspected, on machine tools increases the requirement to have a greater understanding of machine tool capabilities, error sources and factors affecting asset availability. Continuous usage of a machine tool during production processes causes heat generation typically at the moving elements, resulting in distortion of the machine structure. These effects, known as thermal errors, can contribute a significant percentage of the total error in a machine tool. There are a number of design solutions available to the machine tool builder to reduce thermal error including, liquid cooling systems, low thermal expansion materials and symmetric machine tool structures. However, these can only reduce the error not eliminate it altogether. It is therefore advisable, particularly in the production of high value parts, for manufacturers to obtain a thermal profile of their machine, to ensure it is capable of producing in tolerance parts. This paper considers factors affecting practical implementation of condition monitoring of the thermal errors. In particular is the requirement to find links between temperature, which is easily measureable during production and the errors which are not. To this end, various methods of testing including the advantages of thermal images are shown. Results are presented from machines in typical manufacturing environments, which also highlight the value of condition monitoring using thermal analysis.

  11. Tools and techniques for ageing predictions in nuclear reactors through condition monitoring

    International Nuclear Information System (INIS)

    Verma, R.M.P.

    1994-01-01

    To operate the nuclear reactors beyond their design predicted life is gaining importance because of huge replacement and decommissioning costs. But experience shows that nuclear plant safety and reliability may decline in the later years of plant life due to ageing degradation. Ageing of nuclear plant components, structures and systems, if unmitigated reduces their safety margins provided in the design and thus increases risks to public health and safety. These safety margins must be monitored throughout plant service life including any extended life. Condition monitoring of nuclear reactor components/equipment and systems can be done to study the effect of ageing, status of safety margins and effect of corrective and mitigating actions taken. The tools and techniques of condition monitoring are also important in failure trending, predictive maintenance, evaluation of scheduled maintenance, in mitigation of ageing, life extension and reliability studies. (author). 1 fig., 1 annexure

  12. ATLAS distributed computing monitoring tools during the LHC Run I

    International Nuclear Information System (INIS)

    Schovancová, J; Wenaus, T; Campana, S; Girolamo, A Di; Jézéquel, S; Ueda, I

    2014-01-01

    This contribution summarizes evolution of the ATLAS Distributed Computing (ADC) Monitoring project during the LHC Run I. The ADC Monitoring targets at the three groups of customers: ADC Operations team to early identify malfunctions and escalate issues to an activity or a service expert, ATLAS national contacts and sites for the real-time monitoring and long-term measurement of the performance of the provided computing resources, and the ATLAS Management for long-term trends and accounting information about the ATLAS Distributed Computing resources. During the LHC Run I a significant development effort has been invested in standardization of the monitoring and accounting applications in order to provide extensive monitoring and accounting suite. ADC Monitoring applications separate the data layer and the visualization layer. The data layer exposes data in a predefined format. The visualization layer is designed bearing in mind visual identity of the provided graphical elements, and re-usability of the visualization bits across the different tools. A rich family of various filtering and searching options enhancing available user interfaces comes naturally with the data and visualization layer separation. With a variety of reliable monitoring data accessible through standardized interfaces, the possibility of automating actions under well defined conditions correlating multiple data sources has become feasible. In this contribution we discuss also about the automated exclusion of degraded resources and their automated recovery in various activities.

  13. ATLAS Distributed Computing Monitoring tools during the LHC Run I

    Science.gov (United States)

    Schovancová, J.; Campana, S.; Di Girolamo, A.; Jézéquel, S.; Ueda, I.; Wenaus, T.; Atlas Collaboration

    2014-06-01

    This contribution summarizes evolution of the ATLAS Distributed Computing (ADC) Monitoring project during the LHC Run I. The ADC Monitoring targets at the three groups of customers: ADC Operations team to early identify malfunctions and escalate issues to an activity or a service expert, ATLAS national contacts and sites for the real-time monitoring and long-term measurement of the performance of the provided computing resources, and the ATLAS Management for long-term trends and accounting information about the ATLAS Distributed Computing resources. During the LHC Run I a significant development effort has been invested in standardization of the monitoring and accounting applications in order to provide extensive monitoring and accounting suite. ADC Monitoring applications separate the data layer and the visualization layer. The data layer exposes data in a predefined format. The visualization layer is designed bearing in mind visual identity of the provided graphical elements, and re-usability of the visualization bits across the different tools. A rich family of various filtering and searching options enhancing available user interfaces comes naturally with the data and visualization layer separation. With a variety of reliable monitoring data accessible through standardized interfaces, the possibility of automating actions under well defined conditions correlating multiple data sources has become feasible. In this contribution we discuss also about the automated exclusion of degraded resources and their automated recovery in various activities.

  14. Analysis on machine tool systems using spindle vibration monitoring for automatic tool changer

    OpenAIRE

    Shang-Liang Chen; Yin-Ting Cheng; Chin-Fa Su

    2015-01-01

    Recently, the intelligent systems of technology have become one of the major items in the development of machine tools. One crucial technology is the machinery status monitoring function, which is required for abnormal warnings and the improvement of cutting efficiency. During processing, the mobility act of the spindle unit determines the most frequent and important part such as automatic tool changer. The vibration detection system includes the development of hardware and software, such as ...

  15. Detection of system failures in multi-axes tasks. [pilot monitored instrument approach

    Science.gov (United States)

    Ephrath, A. R.

    1975-01-01

    The effects of the pilot's participation mode in the control task on his workload level and failure detection performance were examined considering a low visibility landing approach. It is found that the participation mode had a strong effect on the pilot's workload, the induced workload being lowest when the pilot acted as a monitoring element during a coupled approach and highest when the pilot was an active element in the control loop. The effects of workload and participation mode on failure detection were separated. The participation mode was shown to have a dominant effect on the failure detection performance, with a failure in a monitored (coupled) axis being detected significantly faster than a comparable failure in a manually controlled axis.

  16. Management and monitoring of haemodynamic complications in acute heart failure.

    Science.gov (United States)

    Aspromonte, Nadia; Cruz, Dinna N; Valle, Roberto; Ronco, Claudio

    2011-11-01

    The pathophysiology of acute heart failure syndromes (AHFS), defined as a change or worsening in heart failure symptoms and signs, is complex. The variety of adverse neurohormonal adaptations includes increased levels of plasma renin, aldosterone and angiotensin II, all responsible for cardio-renal dysfunction. In fact, such alterations result in an array of clinical changes that include abnormal haemodynamics, altered ventricular filling pressures, pathological neurohormonal responses, leading to fluid overload, congestion and ultimately heart failure symptoms. Clinical pictures can be various: in spite of a usual improvement in dyspnoea, little weight change and significant morbidity are generally observed during hospitalization. Short-term outcomes are characterized by a high 60-day re-hospitalization and high mortality rates; apparently, both can be predicted from pre-discharge characteristics. The most frequently used treatments for AHF care include diuretics, inotropic agents, and vasodilator/vasoactive agents; however, the final therapeutic strategy is often individualized. Diuretics are currently the most used agents, but resistance to diuretic therapy is common. In addition, several studies have demonstrated that aggressive diuresis can contribute to reduced renal function, and high doses of diuretics have been associated with increased morbidity and mortality. Many patients with AHFS also suffer from acute or from chronic renal dysfunction (cardio-renal syndromes type 1 and 2, respectively), which further complicate the outcomes and treatment strategies. A personalized patient evaluation of the combined heart and kidney functions is advised to implement the best possible multidisciplinary diagnostic and therapeutic approach.

  17. Novel texture-based descriptors for tool wear condition monitoring

    Science.gov (United States)

    Antić, Aco; Popović, Branislav; Krstanović, Lidija; Obradović, Ratko; Milošević, Mijodrag

    2018-01-01

    All state-of-the-art tool condition monitoring systems (TCM) in the tool wear recognition task, especially those that use vibration sensors, heavily depend on the choice of descriptors containing information about the tool wear state which are extracted from the particular sensor signals. All other post-processing techniques do not manage to increase the recognition precision if those descriptors are not discriminative enough. In this work, we propose a tool wear monitoring strategy which relies on the novel texture based descriptors. We consider the module of the Short Term Discrete Fourier Transform (STDFT) spectra obtained from the particular vibration sensors signal utterance as the 2D textured image. This is done by identifying the time scale of STDFT as the first dimension, and the frequency scale as the second dimension of the particular textured image. The obtained textured image is then divided into particular 2D texture patches, covering a part of the frequency range of interest. After applying the appropriate filter bank, 2D textons are extracted for each predefined frequency band. By averaging in time, we extract from the textons for each band of interest the information regarding the Probability Density Function (PDF) in the form of lower order moments, thus obtaining robust tool wear state descriptors. We validate the proposed features by the experiments conducted on the real TCM system, obtaining the high recognition accuracy.

  18. Automatic Monitoring System Design and Failure Probability Analysis for River Dikes on Steep Channel

    Science.gov (United States)

    Chang, Yin-Lung; Lin, Yi-Jun; Tung, Yeou-Koung

    2017-04-01

    The purposes of this study includes: (1) design an automatic monitoring system for river dike; and (2) develop a framework which enables the determination of dike failure probabilities for various failure modes during a rainstorm. The historical dike failure data collected in this study indicate that most dikes in Taiwan collapsed under the 20-years return period discharge, which means the probability of dike failure is much higher than that of overtopping. We installed the dike monitoring system on the Chiu-She Dike which located on the middle stream of Dajia River, Taiwan. The system includes: (1) vertical distributed pore water pressure sensors in front of and behind the dike; (2) Time Domain Reflectometry (TDR) to measure the displacement of dike; (3) wireless floating device to measure the scouring depth at the toe of dike; and (4) water level gauge. The monitoring system recorded the variation of pore pressure inside the Chiu-She Dike and the scouring depth during Typhoon Megi. The recorded data showed that the highest groundwater level insides the dike occurred 15 hours after the peak discharge. We developed a framework which accounts for the uncertainties from return period discharge, Manning's n, scouring depth, soil cohesion, and friction angle and enables the determination of dike failure probabilities for various failure modes such as overtopping, surface erosion, mass failure, toe sliding and overturning. The framework was applied to Chiu-She, Feng-Chou, and Ke-Chuang Dikes on Dajia River. The results indicate that the toe sliding or overturning has the highest probability than other failure modes. Furthermore, the overall failure probability (integrate different failure modes) reaches 50% under 10-years return period flood which agrees with the historical failure data for the study reaches.

  19. Monitoring operational data production applying Big Data tooling

    Science.gov (United States)

    Som de Cerff, Wim; de Jong, Hotze; van den Berg, Roy; Bos, Jeroen; Oosterhoff, Rijk; Klein Ikkink, Henk Jan; Haga, Femke; Elsten, Tom; Verhoef, Hans; Koutek, Michal; van de Vegte, John

    2015-04-01

    Within the KNMI Deltaplan programme for improving the KNMI operational infrastructure an new fully automated system for monitoring the KNMI operational data production systems is being developed: PRISMA (PRocessflow Infrastructure Surveillance and Monitoring Application). Currently the KNMI operational (24/7) production systems consist of over 60 applications, running on different hardware systems and platforms. They are interlinked for the production of numerous data products, which are delivered to internal and external customers. All applications are individually monitored by different applications, complicating root cause and impact analysis. Also, the underlying hardware and network is monitored separately using Zabbix. Goal of the new system is to enable production chain monitoring, which enables root cause analysis (what is the root cause of the disruption) and impact analysis (what other products will be effected). The PRISMA system will make it possible to dispose all the existing monitoring applications, providing one interface for monitoring the data production. For modeling the production chain, the Neo4j Graph database is used to store and query the model. The model can be edited through the PRISMA web interface, but is mainly automatically provided by the applications and systems which are to be monitored. The graph enables us to do root case and impact analysis. The graph can be visualized in the PRISMA web interface on different levels. Each 'monitored object' in the model will have a status (OK, error, warning, unknown). This status is derived by combing all log information available. For collecting and querying the log information Splunk is used. The system is developed using Scrum, by a multi-disciplinary team consisting of analysts, developers, a tester and interaction designer. In the presentation we will focus on the lessons learned working with the 'Big data' tooling Splunk and Neo4J.

  20. Automated speech quality monitoring tool based on perceptual evaluation

    OpenAIRE

    Vozňák, Miroslav; Rozhon, Jan

    2010-01-01

    The paper deals with a speech quality monitoring tool which we have developed in accordance with PESQ (Perceptual Evaluation of Speech Quality) and is automatically running and calculating the MOS (Mean Opinion Score). Results are stored into database and used in a research project investigating how meteorological conditions influence the speech quality in a GSM network. The meteorological station, which is located in our university campus provides information about a temperature,...

  1. Clustering and Flow Conservation Monitoring Tool for Software Defined Networks

    Directory of Open Access Journals (Sweden)

    Jesús Antonio Puente Fernández

    2018-04-01

    Full Text Available Prediction systems present some challenges on two fronts: the relation between video quality and observed session features and on the other hand, dynamics changes on the video quality. Software Defined Networks (SDN is a new concept of network architecture that provides the separation of control plane (controller and data plane (switches in network devices. Due to the existence of the southbound interface, it is possible to deploy monitoring tools to obtain the network status and retrieve a statistics collection. Therefore, achieving the most accurate statistics depends on a strategy of monitoring and information requests of network devices. In this paper, we propose an enhanced algorithm for requesting statistics to measure the traffic flow in SDN networks. Such an algorithm is based on grouping network switches in clusters focusing on their number of ports to apply different monitoring techniques. Such grouping occurs by avoiding monitoring queries in network switches with common characteristics and then, by omitting redundant information. In this way, the present proposal decreases the number of monitoring queries to switches, improving the network traffic and preventing the switching overload. We have tested our optimization in a video streaming simulation using different types of videos. The experiments and comparison with traditional monitoring techniques demonstrate the feasibility of our proposal maintaining similar values decreasing the number of queries to the switches.

  2. Failure mode and effect analysis in blood transfusion: a proactive tool to reduce risks.

    Science.gov (United States)

    Lu, Yao; Teng, Fang; Zhou, Jie; Wen, Aiqing; Bi, Yutian

    2013-12-01

    The aim of blood transfusion risk management is to improve the quality of blood products and to assure patient safety. We utilize failure mode and effect analysis (FMEA), a tool employed for evaluating risks and identifying preventive measures to reduce the risks in blood transfusion. The failure modes and effects occurring throughout the whole process of blood transfusion were studied. Each failure mode was evaluated using three scores: severity of effect (S), likelihood of occurrence (O), and probability of detection (D). Risk priority numbers (RPNs) were calculated by multiplying the S, O, and D scores. The plan-do-check-act cycle was also used for continuous improvement. Analysis has showed that failure modes with the highest RPNs, and therefore the greatest risk, were insufficient preoperative assessment of the blood product requirement (RPN, 245), preparation time before infusion of more than 30 minutes (RPN, 240), blood transfusion reaction occurring during the transfusion process (RPN, 224), blood plasma abuse (RPN, 180), and insufficient and/or incorrect clinical information on request form (RPN, 126). After implementation of preventative measures and reassessment, a reduction in RPN was detected with each risk. The failure mode with the second highest RPN, namely, preparation time before infusion of more than 30 minutes, was shown in detail to prove the efficiency of this tool. FMEA evaluation model is a useful tool in proactively analyzing and reducing the risks associated with the blood transfusion procedure. © 2013 American Association of Blood Banks.

  3. ANN Based Tool Condition Monitoring System for CNC Milling Machines

    Directory of Open Access Journals (Sweden)

    Mota-Valtierra G.C.

    2011-10-01

    Full Text Available Most of the companies have as objective to manufacture high-quality products, then by optimizing costs, reducing and controlling the variations in its production processes it is possible. Within manufacturing industries a very important issue is the tool condition monitoring, since the tool state will determine the quality of products. Besides, a good monitoring system will protect the machinery from severe damages. For determining the state of the cutting tools in a milling machine, there is a great variety of models in the industrial market, however these systems are not available to all companies because of their high costs and the requirements of modifying the machining tool in order to attach the system sensors. This paper presents an intelligent classification system which determines the status of cutt ers in a Computer Numerical Control (CNC milling machine. This tool state is mainly detected through the analysis of the cutting forces drawn from the spindle motors currents. This monitoring system does not need sensors so it is no necessary to modify the machine. The correct classification is made by advanced digital signal processing techniques. Just after acquiring a signal, a FIR digital filter is applied to the data to eliminate the undesired noisy components and to extract the embedded force components. A Wavelet Transformation is applied to the filtered signal in order to compress the data amount and to optimize the classifier structure. Then a multilayer perceptron- type neural network is responsible for carrying out the classification of the signal. Achieving a reliability of 95%, the system is capable of detecting breakage and a worn cutter.

  4. Optical strain for monitoring of concrete failure mechanism with discontinuity.

    Science.gov (United States)

    Deb, Debasis; Bhattacharjee, Sudipta

    2015-12-10

    Finite-element-based digital image correlation (FEM-DIC) is one of the most widely used noncontact techniques in the field of experimental mechanics for measurement of deformation/strain. In this paper, the FEM-DIC method is refined by introducing the concept of multilevel extended digital image correlation (X-DIC), which also can capture deformation across discontinuity planes if they exist in images. Using regular and enhanced displacements at each node, strain tensors are estimated by applying the concept of smooth particle hydrodynamics (SPH). Numerical works are carried out to check the accuracy level of the developed algorithm by considering discrete discontinuity on the surface of a sample. Work is further extended to determine displacements and strains developed at the surface of several cubical concrete samples under uniaxial loading conditions. The tests are conducted until fractures are developed in the post-failure region. Using the concept of cumulative effective strain, a parameter is identified, which can be used as a precursor in the object failure process.

  5. Software Tool for Automated Failure Modes and Effects Analysis (FMEA) of Hydraulic Systems

    DEFF Research Database (Denmark)

    Stecki, J. S.; Conrad, Finn; Oh, B.

    2002-01-01

    management techniques and a vast array of computer aided techniques are applied during design and testing stages. The paper present and discusses the research and development of a software tool for automated failure mode and effects analysis - FMEA - of hydraulic systems. The paper explains the underlying...

  6. Sentinel-2 ArcGIS Tool for Environmental Monitoring

    Science.gov (United States)

    Plesoianu, Alin; Cosmin Sandric, Ionut; Anca, Paula; Vasile, Alexandru; Calugaru, Andreea; Vasile, Cristian; Zavate, Lucian

    2017-04-01

    This paper addresses one of the biggest challenges regarding Sentinel-2 data, related to the need of an efficient tool to access and process the large collection of images that are available. Consequently, developing a tool for the automation of Sentinel-2 data analysis is the most immediate need. We developed a series of tools for the automation of Sentinel-2 data download and processing for vegetation health monitoring. The tools automatically perform the following operations: downloading image tiles from ESA's Scientific Hub or other venders (Amazon), pre-processing of the images to extract the 10-m bands, creating image composites, applying a series of vegetation indexes (NDVI, OSAVI, etc.) and performing change detection analyses on different temporal data sets. All of these tools run in a dynamic way in the ArcGIS Platform, without the need of creating intermediate datasets (rasters, layers), as the images are processed on-the-fly in order to avoid data duplication. Finally, they allow complete integration with the ArcGIS environment and workflows

  7. Managed PACS operation with an automatic monitoring tool

    Science.gov (United States)

    Zhang, Jianguo; Han, Ruolin; Wu, Dongqing; Zhang, Xiaoyan; Zhuang, Jun; Feng, Jie; Wang, Mingpeng; Zhang, Guozhen; Wang, Cuanfu

    2002-05-01

    Huadong hospital in Shanghai with 800 beds provides health care services for inpatients and outpatients, as well as special senior and VIP patients. In order to move to digital imaging based radiology practice, and also provide better intra-hospital consultation services for senior and VIP patients, we started to implement PACS for hospital wide services from 1999, and also designed and developed an automatic monitoring system (AMS) to monitor and control PACS operation and dataflow to decrease the total cost of ownership for PACS operation. We installed the AMS on top of the Huadong Hospital PACS in the May of 2001. The installation was painless, did not interrupt the normal PACS operation, and took only one month. The PACS administrators with the AMS can now monitor and control the entire PACS operation in real time, and also track patient and image data flow automatically. These features make administrators take proper action even before user's complaint if any failure happened in any PACS component or process, they reduce the size of the management team, and decrease total cost of PACS ownership.

  8. E-beam column monitoring for improved CD SEM stability and tool matching

    Science.gov (United States)

    Hayes, Timothy S.; Henninger, Randall S.

    2000-06-01

    Tool matching is an important metric for in-line semiconductor metrology systems. The ability to obtain the same measurement results on two or more systems allows a semiconductor fabrication facility (fab) to deploy product in an efficient manner improving overall equipment efficiency (OEE). Many parameters on the critical dimension scanning electron microscopes (CDSEMs) can affect the long-term precision component to the tool-matching metric. One such class of parameters is related to the electron beam column stability. The alignment and condition of the gun and apertures, as well as astigmatism correction, have all been found to affect the overall measurements of the CDSEM. These effects are now becoming dominant factors in sub-3nm tool-matching criteria. This paper discusses the methodologies of column parameter monitoring and actions and controls for improving overall stability. Results have shown that column instabilities caused by contamination, gun fluctuations, component failures, detector efficiency, and external issues can be identified through parameter monitoring. The Applied Materials (AMAT) 7830 Series CDSEMs evaluated at IBM's Burlington, Vermont manufacturing facility have demonstrated 5 nm tool matching across 11 systems, which has resulted in non-dedicated product deployment and has significantly reduced cost of ownership.

  9. Estimating changes in cardiac output using an implanted hemodynamic monitor in heart failure patients

    DEFF Research Database (Denmark)

    Ståhlberg, Marcus; Damgaard, Morten; Ersgård, David

    2010-01-01

    OBJECTIVES: The aim of this study was to evaluate an algorithm that estimates changes in cardiac output (CO) from right ventricular (RV) pressure waveforms derived from an implantable hemodynamic monitor (IHM) in heart failure patients. DESIGN: Twelve heart failure patients (NYHA II-III, EF 32...... was -0.39 L/min (11%). Limits of agreement were +/-1.56 L/min and relative error was 21%. CONCLUSIONS: A simple algorithm based on RV pressure wave form characteristics derived from an IHM can be used to estimate changes in CO in heart failure patients. These findings encourage further research aiming...

  10. Is age a factor in the success or failure of remote monitoring in heart failure? Telemonitoring and structured telephone support in elderly heart failure patients.

    Science.gov (United States)

    Inglis, Sally C; Conway, Aaron; Cleland, John Gf; Clark, Robyn A

    2015-06-01

    There are few data regarding the effectiveness of remote monitoring for older people with heart failure. We conducted a post-hoc sub-analysis of a previously published large Cochrane systematic review and meta-analysis of relevant randomized controlled trials to determine whether structured telephone support and telemonitoring were effective in this population. A post hoc sub-analysis of a systematic review and meta-analysis that applied the Cochrane methodology was conducted. Meta-analyses of all-cause mortality, all-cause hospitalizations and heart failure-related hospitalizations were performed for studies where the mean or median age of participants was 70 or more years. The mean or median age of participants was 70 or more years in eight of the 16 (n=2659/5613; 47%) structured telephone support studies and four of the 11 (n=894/2710; 33%) telemonitoring studies. Structured telephone support (RR 0.80; 95% CI=0.63-1.00) and telemonitoring (RR 0.56; 95% CI=0.41-0.76) interventions reduced mortality. Structured telephone support interventions reduced heart failure-related hospitalizations (RR 0.81; 95% CI=0.67-0.99). Despite a systematic bias towards recruitment of individuals younger than the epidemiological average into the randomized controlled trials, older people with heart failure did benefit from structured telephone support and telemonitoring. These post-hoc sub-analysis results were similar to overall effects observed in the main meta-analysis. While further research is required to confirm these observational findings, the evidence at hand indicates that discrimination by age alone may be not be appropriate when inviting participation in a remote monitoring service for heart failure. © The European Society of Cardiology 2014.

  11. Configuration monitoring tool for large-scale distributed computing

    International Nuclear Information System (INIS)

    Wu, Y.; Graham, G.; Lu, X.; Afaq, A.; Kim, B.J.; Fisk, I.

    2004-01-01

    The Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) at CERN will likely use a grid system to achieve much of its offline processing need. Given the heterogeneous and dynamic nature of grid systems, it is desirable to have in place a configuration monitor. The configuration monitoring tool is built using the Globus toolkit and web services. It consists of an information provider for the Globus MDS, a relational database for keeping track of the current and old configurations, and client interfaces to query and administer the configuration system. The Grid Security Infrastructure (GSI), together with EDG Java Security packages, are used for secure authentication and transparent access to the configuration information across the CMS grid. This work has been prototyped and tested using US-CMS grid resources

  12. A tool for monitoring lecturers’ interactions with Learning Management Systems

    Directory of Open Access Journals (Sweden)

    Magdalena Cantabella

    2016-12-01

    Full Text Available Learning Management Systems’ (LMS interaction mechanisms are mainly focused on the improvement of students’ experiences and academic results. However, special attention should also be given to the interaction between these LMS and other actors involved in the educational process. This paper specifically targets the interaction of degree coordinators with LMS when monitoring lecturers’ performance, especially in an online mode. The methodology is guided by the following three objectives: (1 analysis of the limitations of monitoring lecturers in current LMS; (2 development of software program to overcome such limitations; and (3 empirical evaluation of the proposed program. The results show that this type of tool helps coordinators to intuitively and efficiently analyze the status of the subjects taught in their degree programs.

  13. Configuration monitoring tool for large-scale distributed computing

    CERN Document Server

    Wu, Y; Fisk, I; Graham, G; Kim, B J; Lü, X

    2004-01-01

    The Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC) at CERN will likely use a grid system to achieve much of its offline processing need. Given the heterogeneous and dynamic nature of grid systems, it is desirable to have in place a configuration monitor. The configuration monitoring tool is built using the Globus toolkit and web services. It consists of an information provider for the Globus MDS, a relational database for keeping track of the current and old configurations, and client interfaces to query and administer the configuration system. The Grid Security Infrastructure (GSI), together with EDG Java Security packages, are used for secure authentication and transparent access to the configuration information across the CMS grid. This work has been prototyped and tested using US-CMS grid resources.

  14. FT-NIR: A Tool for Process Monitoring and More.

    Science.gov (United States)

    Martoccia, Domenico; Lutz, Holger; Cohen, Yvan; Jerphagnon, Thomas; Jenelten, Urban

    2018-03-30

    With ever-increasing pressure to optimize product quality, to reduce cost and to safely increase production output from existing assets, all combined with regular changes in terms of feedstock and operational targets, process monitoring with traditional instruments reaches its limits. One promising answer to these challenges is in-line, real time process analysis with spectroscopic instruments, and above all Fourier-Transform Near Infrared spectroscopy (FT-NIR). Its potential to afford decreased batch cycle times, higher yields, reduced rework and minimized batch variance is presented and application examples in the field of fine chemicals are given. We demonstrate that FT-NIR can be an efficient tool for improved process monitoring and optimization, effective process design and advanced process control.

  15. Advanced software tools for digital loose part monitoring systems

    International Nuclear Information System (INIS)

    Ding, Y.

    1996-01-01

    The paper describes two software modules as analysis tools for digital loose part monitoring systems. The first module is called acoustic module which utilizes the multi-media features of modern personal computers to replay the digital stored short-time bursts with sufficient length and in good quality. This is possible due to the so-called puzzle technique developed at ISTec. The second module is called classification module which calculates advanced burst parameters and classifies the acoustic events in pre-defined classes with the help of an artificial multi-layer perception neural network trained with the back propagation algorithm. (author). 7 refs, 7 figs

  16. New tools to monitor social networks in business sector

    Directory of Open Access Journals (Sweden)

    Cosmin Cătălin Olteanu

    2014-05-01

    Full Text Available The main purpose of the paper is to illustrate the importance of new software tools that can help your business to monitor all social networks and combat all negative messages about your products or services. We really need this kind of software to see where all viral messages are in every social network of your products or services and take all measures necessary to diminish negative feelings. In the past we had seen some companies that have ignored negative viral messages and in the end that ended in negative profit figures.

  17. MONITORING OF LARGE INSTABLE AREAS: system reliability and new tools.

    Science.gov (United States)

    Leandro, G.; Mucciarelli, M.; Pellicani, R.; Spilotro, G.

    2009-04-01

    emission (AE) measurement has constituted for decades a monitoring system able to define precisely, in presence of a favourable geometry, the micro-cracks pattern, describing both propagation of cracks and formation of failure surfaces. In stiff materials the deformations are associated to micro distortions or micro failures, with release of vibrational energy in the acoustic range of the frequencies. Therefore, the survey of such precursors can result extremely profitable to the goals of an early recognition of the evolution of stress states towards the failure. For this reason, the survey of AE in geological materials, besides monitoring and forecast of landslide movements, has revealed very useful in other fields, as the safety auscultation of the mines, the stability of underground deposits of liquid and gaseous hydrocarbons and radioactive cinders, and the forecast of avalanches. The studies in literature, especially in the mining field, have underlined that the typical emission is in the low frequencies range, where waves suffer a limited attenuation in the propagation through the rocks. The generation of micro-fractures is, on the other hand, accompanied by acoustic emission at higher frequencies. The Authors in the last years have experienced the possibility of acoustic emission measurement, finally coming to the design and construction of a simple mono-channel device. This device is unable to determine the location of the spreading point of new failures, which is possible only with more than three channels devices. A mono-channel device can realize: a - recognition of the phenomenon (definition of AE frequency range of rock mass under examination, characteristic ampleness), b - recognition of the physiological activity (number of issues in time), c - enucleation of the remarkable noises from those physiological or occasional produced outside. The third point is realized through the transformation of sampled noise in FFT, for which is easier to define a threshold

  18. Monitoring and Reporting Tools of the International Data Centre and International Monitoring System

    Science.gov (United States)

    Lastowka, L.; Anichenko, A.; Galindo, M.; Villagran Herrera, M.; Mori, S.; Malakhova, M.; Daly, T.; Otsuka, R.; Stangel, H.

    2007-05-01

    The Comprehensive Test-Ban Treaty (CTBT) which prohibits all nuclear explosions was opened for signature in 1996. Since then, the Preparatory Commission for the CTBT Organization has been working towards the establishment of a global verification regime to monitor compliance with the ban on nuclear testing. The International Monitoring System (IMS) comprises facilities for seismic, hydroacoustic, infrasound and radionuclide monitoring, and the means of communication. This system is supported by the International Data Centre (IDC), which provides objective products and services necessary for effective global monitoring. Upon completion of the IMS, 321 stations will be contributing to both near real-time and reviewed data products. Currently there are 194 facilities in IDC operations. This number is expected to increase by about 40% over the next few years, necessitating methods and tools to effectively handle the expansion. The requirements of high data availability as well as operational transparency are fundamental principals of IMS network operations, therefore, a suite of tools for monitoring and reporting have been developed. These include applications for monitoring Global Communication Infrastructure (GCI) links, detecting outages in continuous and segmented data, monitoring the status of data processing and forwarding to member states, and for systematic electronic communication and problem ticketing. The operation of the IMS network requires the help of local specialists whose cooperation is in some cases ensured by contracts or other agreements. The PTS (Provisional Technical Secretariat) strives to make the monitoring of the IMS as standardized and efficient as possible, and has therefore created the Operations Centre in which the use of most the tools are centralized. Recently the tasks of operations across all technologies, including the GCI, have been centralized within a single section of the organization. To harmonize the operations, an ongoing State

  19. Practical clinical tool to monitor dementia symptoms: the HABC-Monitor

    Science.gov (United States)

    Monahan, Patrick O; Boustani, Malaz A; Alder, Catherine; Galvin, James E; Perkins, Anthony J; Healey, Patrick; Chehresa, Azita; Shepard, Polly; Bubp, Corby; Frame, Amie; Callahan, Chris

    2012-01-01

    Background Dementia care providers need a clinical assessment tool similar to the blood pressure cuff (sphygmomanometer) used by clinicians and patients for managing hypertension. A “blood pressure cuff ” for dementia would be an inexpensive, simple, user-friendly, easily standardized, sensitive to change, and widely available multidomain instrument for providers and informal caregivers to measure severity of dementia symptoms. The purpose of this study was to assess the reliability and validity of the Healthy Aging Brain Care Monitor (HABC-Monitor) for measuring and monitoring the severity of dementia symptoms through caregiver reports. Methods The first prototype of the HABC-Monitor was developed in collaboration with the Indianapolis Discovery Network for Dementia, which includes 200 members representing 20 disciplines from 20 local organizations, and an expert panel of 22 experts in dementia care and research. The HABC-Monitor has three patient symptom domains (cognitive, functional, behavioral/psychological) and a caregiver quality of life domain. Patients (n = 171) and their informal caregivers (n = 171) were consecutively approached and consented during, or by phone shortly following, a patient’s routine visit to their memory care provider. Results The HABC-Monitor demonstrated good internal consistency (0.73–0.92); construct validity indicated by correlations with the caregiver-reported Neuropsychiatric Inventory (NPI) total score and NPI caregiver distress score; sensitivity to three-month change compared with NPI “reliable change” groups; and known-groups validity, indicated by significant separation of Mini-Mental Status Examination severity groups and clinical diagnostic groups. Although not designed as a screening study, there was evidence for good operating characteristics, according to area under the receiver-operator curve with respect to gold standard clinical diagnoses, relative to Mini-Mental Status Examination or NPI. Conclusion The

  20. Tool wear monitoring using neuro-fuzzy techniques: a comparative study in a turning process

    OpenAIRE

    Gajate, Agustín; Haber Guerra, Rodolfo E.; Toro Matamoros, Raúl Mario del; Vega, Pastora; Bustillo, Andrés

    2012-01-01

    Tool wear detection is a key issue for tool condition monitoring. The maximization of useful tool life is frequently related with the optimization of machining processes. This paper presents two model-based approaches for tool wear monitoring on the basis of neuro-fuzzy techniques. The use of a neuro-fuzzy hybridization to design a tool wear monitoring system is aiming at exploiting the synergy of neural networks and fuzzy logic, by combining human reasoning with learning and connectionist st...

  1. An intelligent condition monitoring system for on-line classification of machine tool wear

    Energy Technology Data Exchange (ETDEWEB)

    Fu Pan; Hope, A.D.; Javed, M. [Systems Engineering Faculty, Southampton Institute (United Kingdom)

    1997-12-31

    The development of intelligent tool condition monitoring systems is a necessary requirement for successful automation of manufacturing processes. This presentation introduces a tool wear monitoring system for milling operations. The system utilizes power, force, acoustic emission and vibration sensors to monitor tool condition comprehensively. Features relevant to tool wear are drawn from time and frequency domain signals and a fuzzy pattern recognition technique is applied to combine the multisensor information and provide reliable classification results of tool wear states. (orig.) 10 refs.

  2. Full autonomous monitoring tools inside nuclear reactor building

    International Nuclear Information System (INIS)

    Giraud, A.; Veau, J.

    2009-01-01

    In this paper, we define, design and test a radiation tolerant autonomous monitoring tool for nuclear embedded applications. The goal of the instrumentation system was to record the values of some parameters such as dose, temperature or vibrations appearing inside the containment building of nuclear power plants. The knowledge of these parameters will be a good help for predictive maintenance of the power plant components. For the design of the monitoring tool, we rely on commercial-off-the-shelf (COTS) low power electronic components to use battery-supplied power. A large amount of components starting from discrete transistors or logic units to memories and micro-controllers was associated to define and design a prototype. We then confirm the environment conditions tolerance estimated to up to 2 kGy of total dose and 80 C for temperature by on-line irradiation experiments for individual components and functions and prototypes. Two different sets of about 60 systems were realised as industrial products and then installed in EDF facilities. They were exploited during NPPs operating times of about eighteen months. This large scale experiment was concluded with the inspection of some withdrawn systems. No major degradations were observed showing the efficiency of the hardening method allowing regular use of COTS

  3. GenSAA: A tool for advancing satellite monitoring with graphical expert systems

    Science.gov (United States)

    Hughes, Peter M.; Luczak, Edward C.

    1993-01-01

    During numerous contacts with a satellite each day, spacecraft analysts must closely monitor real time data for combinations of telemetry parameter values, trends, and other indications that may signify a problem or failure. As satellites become more complex and the number of data items increases, this task is becoming increasingly difficult for humans to perform at acceptable performance levels. At the NASA Goddard Space Flight Center, fault-isolation expert systems have been developed to support data monitoring and fault detection tasks in satellite control centers. Based on the lessons learned during these initial efforts in expert system automation, a new domain-specific expert system development tool named the Generic Spacecraft Analyst Assistant (GenSAA) is being developed to facilitate the rapid development and reuse of real-time expert systems to serve as fault-isolation assistants for spacecraft analysts. Although initially domain-specific in nature, this powerful tool will support the development of highly graphical expert systems for data monitoring purposes throughout the space and commercial industry.

  4. Design and performance of a multisensor heart failure monitoring algorithm: results from the multisensor monitoring in congestive heart failure (MUSIC) study.

    Science.gov (United States)

    Anand, Inder S; Tang, W H Wilson; Greenberg, Barry H; Chakravarthy, Niranjan; Libbus, Imad; Katra, Rodolphe P

    2012-04-01

    Remote monitoring of heart failure (HF) patients may help in the early detection of acute decompensation before the onset of symptoms, providing the opportunity for early intervention to reduce HF-related hospitalizations, improve outcomes, and lower costs. MUSIC is a multicenter nonrandomized study designed to develop and validate an algorithm for prediction of impending acute HF decompensation with the use of physiologic signals obtained from an external device adhered to the chest. A total of 543 HF patients (206 development, 337 validation) with ejection fraction ≤40% and a recent HF admission were enrolled. Patients were remotely monitored for 90 days using a multisensor device. Accounting for device failure and patient withdrawal, 314 patients (114 development, 200 validation) were included in the analysis. Development patient data were used to develop a multiparameter HF detection algorithm. Algorithm performance in the development cohort had 65% sensitivity, 90% specificity, and a false positive rate of 0.7 per patient-year for detection of HF events. In the validation cohort, algorithm performance met the prespecified end points with 63% sensitivity, 92% specificity, and a false positive rate of 0.9 per patient-year. The overall rate of significant adverse skin response was 0.4%. Using an external multisensor monitoring system, an HF decompensation prediction algorithm was developed that met the prespecified performance end point. Further studies are required to determine whether the use of this system will improve patient outcomes. Published by Elsevier Inc.

  5. Role of telephone monitoring in patients with chronic heart failure: theory and practical implications

    Directory of Open Access Journals (Sweden)

    Host JF

    2014-02-01

    Full Text Available Jennifer Farroni Host, Ayesha Hasan Division of Cardiovascular Medicine, Wexner Medical Center at the Ohio State University, Columbus, OH, USA Abstract: With the aging of the world's population and the rise of chronic illness such as heart failure (HF, the economic burden, number of hospitalizations, and penalties imposed for failure to meet hospital readmission expectations will continue to rise, thus increasing pressure on clinicians to utilize successful HF monitoring interventions to improve these measures. Telephone monitoring in patients with chronic HF utilizes a proactive approach in the care of such patients, and for this review is grouped into three categories, ie, structured telephone support, telemonitoring, and remote implantable device monitoring. Earlier studies on structured telephone support and telemonitoring suggested a clear benefit on mortality and HF admissions, although several recent large, randomized controlled studies have been neutral. Optimizing medical therapy requires an accurate assessment of volume status by the clinician; therefore, symptom report and weight monitoring alone are often challenging in the identification of true HF decompensation because they are not very sensitive markers. The use of remote monitoring technology for follow-up of patients with implantable devices, including implantable cardiac defibrillators and cardiac resynchronization therapy devices, can aid in identifying HF decompensation. Self-care or self-management is an essential component of a chronic illness such as HF, and it is important for such patients to be engaged in their health care to best utilize the telephone monitoring intervention. System design, adequate staffing, patient satisfaction, and treatment adherence are important for success of the telemonitoring system. Telephone monitoring seems to be an effective approach in the chronic HF population. In the future, large-scale telemonitoring programs may come into place as

  6. Breath acetone analyzer: diagnostic tool to monitor dietary fat loss.

    Science.gov (United States)

    Kundu, S K; Bruzek, J A; Nair, R; Judilla, A M

    1993-01-01

    Acetone, a metabolite of fat catabolism, is produced in excessive amounts in subjects on restricted-calorie weight-loss programs. Breath acetone measurements are useful as a motivational tool during dieting and for monitoring the effectiveness of weight-loss programs. We have developed a simple, easy-to-read method that quantifies the amount of acetone in a defined volume of exhaled breath after trapping the sample in a gas-analyzer column. The concentration of acetone, as measured by the length of a blue color zone in the analyzer column, correlates with results obtained by gas chromatography. Using the breath acetone analyzer to quantify breath acetone concentrations of dieting subjects, we established a correlation between breath acetone concentration and rate of fat loss (slope 52.2 nmol/L per gram per day, intercept 15.3 nmol/L, n = 78, r = 0.81). We also discussed the possibility of using breath acetone in diabetes management.

  7. Network analytical tool for monitoring global food safety highlights China.

    Directory of Open Access Journals (Sweden)

    Tamás Nepusz

    Full Text Available BACKGROUND: The Beijing Declaration on food safety and security was signed by over fifty countries with the aim of developing comprehensive programs for monitoring food safety and security on behalf of their citizens. Currently, comprehensive systems for food safety and security are absent in many countries, and the systems that are in place have been developed on different principles allowing poor opportunities for integration. METHODOLOGY/PRINCIPAL FINDINGS: We have developed a user-friendly analytical tool based on network approaches for instant customized analysis of food alert patterns in the European dataset from the Rapid Alert System for Food and Feed. Data taken from alert logs between January 2003-August 2008 were processed using network analysis to i capture complexity, ii analyze trends, and iii predict possible effects of interventions by identifying patterns of reporting activities between countries. The detector and transgressor relationships are readily identifiable between countries which are ranked using i Google's PageRank algorithm and ii the HITS algorithm of Kleinberg. The program identifies Iran, China and Turkey as the transgressors with the largest number of alerts. However, when characterized by impact, counting the transgressor index and the number of countries involved, China predominates as a transgressor country. CONCLUSIONS/SIGNIFICANCE: This study reports the first development of a network analysis approach to inform countries on their transgressor and detector profiles as a user-friendly aid for the adoption of the Beijing Declaration. The ability to instantly access the country-specific components of the several thousand annual reports will enable each country to identify the major transgressors and detectors within its trading network. Moreover, the tool can be used to monitor trading countries for improved detector/transgressor ratios.

  8. Challenges in Getting Building Performance Monitoring Tools for Everyday Use: User Experiences with A New Tool

    Directory of Open Access Journals (Sweden)

    Heikki Ihasalo

    2014-05-01

    Full Text Available There is a need for building performance monitoring because it is common that buildings do not perform as intended. A number of advanced tools for the purpose have been developed within the last tens of years. However, these tools have not been widely adopted in real use. A new tool presented here utilizes building automation data and transforms the data into a set of performance metrics, and is capable of visualizing building performance from energy, indoor conditions, and HVAC (heating, ventilation and air conditioning system perspectives. The purpose of this paper is to study the users’ perceptions of the use of tool. The research method was semi-structured interviews. Although the users were satisfied with the solution in general, it was not taken into operative use. The main challenges with the use of the solution were related to accessibility, trust, and management practices. The interviewees were struggling to manage with numerous information systems and therefore had problems in finding the solution and authenticating to it. All the interviewees did not fully trust the solution, since they did not entirely understand what the performance metrics meant or because the solution had limitations in assessing building performance. Management practices are needed to support the performance measurement philosophy.

  9. TRTViewer: the ATLAS TRT detector monitoring and diagnostics tool.

    CERN Document Server

    Smirnov, S Yu; The ATLAS collaboration

    2011-01-01

    The Transition Radiation Tracker (TRT) is the outermost of the three sub-systems of the ATLAS Inner Detector at the Large Hadron Collider (LHC) at CERN. It consists of close to 300000 thin-walled drift tubes (straws), providing on average 30 two-dimensional space points with 130 um resolution for charged particle tracks. Along with continuous tracking, it provides particle identification capability through the detection of transition radiation X-ray photons generated by high velocity particles in the many polymer fibers or films that fill the spaces between the straws, thus enabling the detector to separate electrons from pions over the energy range between 1 and 200 GeV. The TRT performance and its operation conditions have been permanently monitored during all commissioning and data-taking periods using various software tools, one of which - TRTViewer - is described in the present paper. The TRTViewer is the dedicated program for monitoring the TRT raw data quality and detector performance at different hard...

  10. Diagnostic value of different adherence measures using electronic monitoring and virologic failure as reference standards.

    Science.gov (United States)

    Deschamps, Ann E; De Geest, Sabina; Vandamme, Anne-Mieke; Bobbaers, Herman; Peetermans, Willy E; Van Wijngaerden, Eric

    2008-09-01

    Nonadherence to antiretroviral therapy is a substantial problem in HIV and jeopardizes the success of treatment. Accurate measurement of nonadherence is therefore imperative for good clinical management but no gold standard has been agreed on yet. In a single-center prospective study nonadherence was assessed by electronic monitoring: percentage of doses missed and drug holidays and by three self reports: (1) a visual analogue scale (VAS): percentage of overall doses taken; (2) the Swiss HIV Cohort Study Adherence Questionnaire (SHCS-AQ): percentage of overall doses missed and drug holidays and (3) the European HIV Treatment Questionnaire (EHTQ): percentage of doses missed and drug holidays for each antiretroviral drug separately. Virologic failure prospectively assessed during 1 year, and electronic monitoring were used as reference standards. Using virologic failure as reference standard, the best results were for (1) the SHCS-AQ after electronic monitoring (sensitivity, 87.5%; specificity, 78.6%); (2) electronic monitoring (sensitivity, 75%; specificity, 85.6%), and (3) the VAS combined with the SHCS-AQ before electronic monitoring (sensitivity, 87.5%; specificity, 58.6%). The sensitivity of the complex EHTQ was less than 50%. Asking simple questions about doses taken or missed is more sensitive than complex questioning about each drug separately. Combining the VAS with the SHCS-AQ seems a feasible nonadherence measure for daily clinical practice. Self-reports perform better after electronic monitoring: their diagnostic value could be lower when given independently.

  11. Design of the Multi-Sensor Monitoring in Congestive Heart Failure (MUSIC) study: prospective trial to assess the utility of continuous wireless physiologic monitoring in heart failure.

    Science.gov (United States)

    Anand, Inder S; Greenberg, Barry H; Fogoros, Richard N; Libbus, Imad; Katra, Rodolphe P

    2011-01-01

    Remote monitoring of heart failure (HF) patients may help in the early detection of acute HF decompensation before the onset of symptoms. Appropriate early intervention in these patients may reduce HF-related hospitalizations and costs. The MUSIC (Multi-Sensor Monitoring in Congestive Heart Failure) study comprises 2 multicenter nonrandomized phases (MUSIC-Development and MUSIC-Validation) designed to develop and validate an algorithm for the prediction of acute HF decompensation using multiple physiologic signals obtained from an external, adherent, multisensor system capable of intermittent transmission of physiologic signals. Data obtained from MUSIC-Development will be used to develop the algorithm to predict HF decompensation. The algorithm will be validated in MUSIC-Validation with the objectives of ≥ 60% sensitivity for correctly predicting an acute HF event, a false-positive patient status signal rate of ≤ 1.0 per patient-year, and a safety endpoint of ≤ 5% of patients experiencing significant adverse skin conditions related to the prolonged wearing of the adherent device. A total of 542 patients in New York Heart Association functional class III-IV HF, with ejection fraction ≤ 40% and a recent HF admission, are enrolled in MUSIC-Development (n = 180) and MUSIC-Validation (n = 362). All patients are remotely monitored for 90 days using the Corventis multisensor system that transmits bioimpedance, electrocardiogram, and accelerometer data. The MUSIC study has completed patient enrollment and follow-up in both phases. Once algorithm development is complete from the MUSIC-Development phase, the sequestered data set from the MUSIC-Validation phase will be used for algorithm validation. Published by Elsevier Inc.

  12. Personnel reliability impact on petrochemical facilities monitoring system's failure skipping probability

    Science.gov (United States)

    Kostyukov, V. N.; Naumenko, A. P.

    2017-08-01

    The paper dwells upon urgent issues of evaluating impact of actions conducted by complex technological systems operators on their safe operation considering application of condition monitoring systems for elements and sub-systems of petrochemical production facilities. The main task for the research is to distinguish factors and criteria of monitoring system properties description, which would allow to evaluate impact of errors made by personnel on operation of real-time condition monitoring and diagnostic systems for machinery of petrochemical facilities, and find and objective criteria for monitoring system class, considering a human factor. On the basis of real-time condition monitoring concepts of sudden failure skipping risk, static and dynamic error, monitoring systems, one may solve a task of evaluation of impact that personnel's qualification has on monitoring system operation in terms of error in personnel or operators' actions while receiving information from monitoring systems and operating a technological system. Operator is considered as a part of the technological system. Although, personnel's behavior is usually a combination of the following parameters: input signal - information perceiving, reaction - decision making, response - decision implementing. Based on several researches on behavior of nuclear powers station operators in USA, Italy and other countries, as well as on researches conducted by Russian scientists, required data on operator's reliability were selected for analysis of operator's behavior at technological facilities diagnostics and monitoring systems. The calculations revealed that for the monitoring system selected as an example, the failure skipping risk for the set values of static (less than 0.01) and dynamic (less than 0.001) errors considering all related factors of data on reliability of information perception, decision-making, and reaction fulfilled is 0.037, in case when all the facilities and error probability are under

  13. Efficacy of medication directed by home-monitoring cardiac resynchronization therapy in chronic heart failure patients.

    Science.gov (United States)

    Yang, Hao; Zhang, Fei-fei; Peng, Xin-hui; Zhao, Dong-hua; Peng, Jian

    2014-03-01

    PATIENTS with chronic heart failure (CHF) have a high incidence of atrial/ventricular arrhythmias which seriously affect life span and quality of life. Cardiac re-synchronization therapy (CRT) can improve cardiac function and reverse myocardial remodeling, therefore improving the quality of life and reducing mortality. CRT with Home-Monitoring (HM) can be used to monitor cardiac arrhythmias and other heart physiological indexes such as intrathoracic impedance and hemodynamics. Through wireless satellites, the data from the patients are sent to a monitor center for analysis. Doctors can identify emergent information and make a rapid diagnosis based on the information stored in the monitor center. CRT with HM has been verified as a valid method to optimize drug treatment according to individual parameters.

  14. A multi-sensor approach to landslide monitoring of rainfall-induced failures in Scotland.

    Science.gov (United States)

    Gilles, Charlie; Hoey, Trevor; Williams, Richard

    2017-04-01

    Landslides are of significant interest in upland areas of the United Kingdom due to their: complex mechanics, potential to channelize into hazardous debris flows and their costly potential impacts on infrastructure. The British Geological Survey National Landslide Database contains an average of 367 landslides per year (from 1970). Slope failures in the UK are typically triggered by extended periods of intense rainfall, and can occur at any time of year. In any given rainfall event that triggers landslides, most potentially vulnerable slopes remain stable. Accurate warning systems would be facilitated by identifying landslide precursors prior to failure events. This project tests whether such precursors can be identified in the valley of Glen Ogle, Scotland (87 km north-west of Edinburgh), where in summer 2004 two debris flows blocked the main road (A85), trapping fifty-seven people. Two adjacent sites have been selected on a west facing slope in Glen Ogle, one of which (the control) has been stable since at least 2004 and the other failed in 2004 and remains unstable. Understanding the immediate causes and antecedent conditions responsible for landslides requires a multi-scale approach. This project uses multiple sensors to assess failure mechanisms of landslides in Glen Ogle: (1) 3-monthly, high (1.8 arcsec) resolution terrestrial laser scanning of topography to detect changes and identify patterns of movement prior to major failure, using the Riegl VZ-1000 (NERC Geophysical Equipment Fund); (2) rainfall and soil moisture data to monitor pore pressure of landslide failure prior to and after hydrologically triggered events; (3) monitoring ground motion using grain-scale sensors which are becoming lower cost, more efficient in terms of power, and can be wirelessly networked these will be used to detect small scale movement of the landslide. Comparative data from the control and test sites will be presented, from which patterns of surface deformation between failure

  15. Data Quality Monitoring : Automatic MOnitoRing Environment (AMORE ) Web Administration Tool in ALICE Experiment

    CERN Document Server

    Nagi, Imre

    2013-01-01

    ALICE (A Large Ion Collider Experiment) is the heavy-ion detector designed to study the physics of strongly interacting matter and the quark-gluon plasma at the CERN Large Hadron Collider (LHC). The quality of the acquired data evolves over time depending on the status of the detectors, its components and the operating environment. To get an excellent performance of detector, all detector configurations have to be set perfectly so that the data-taking can be done in an optimal way. This report describes a new implementation of the administration tools of the ALICE’s DQM framework called AMORE (Automatic MonitoRing Environment) with web technologies.

  16. Development of a permanent installation tool for structural health monitoring of pipelines

    International Nuclear Information System (INIS)

    Gan, Tat Hean; Jackson, Paul; France, Andy; Daniel, Ian

    2009-01-01

    There are over 10 million kilometers of pipes and pipelines around the world that carry hazardous fluids. These fluids include oil, oil products, chemicals such as solvents, caustics, acids, corrosives and combustibles and gases, often at high pressure and temperature. These pipes are subjected to corrosion by the environment and contents. The inspection of a great majority of the pipes is mandatory to ascertain their structural integrity as failure to inspect can result in leakage of hazardous material into the environment and even explosion. This paper presents a new and novel permanently installed tool-head called Teletest Perm-A-Mount. This device consists of a transducer array attached directly to the pipe surface providing all the benefits of Teletest Focus Guided Wave Inspection without the problem of access. Perm-A-Mount is a low cost, long life tool installation intended for regular monitoring of piping systems in environmentally hostile, safety critical or difficult to access areas. The installation process has been developed in conjunction with TWI Ltd surfacing and corrosion departments and tested to ensure that the tool will not be a future source of corrosion in piping systems. In this paper, potential benefits will be discussed together with examples of industrial applications of the newly developed system. (author)

  17. Immunisation Information Systems - useful tools for monitoring vaccination programmes in EU/EEA countries, 2016.

    Science.gov (United States)

    Derrough, Tarik; Olsson, Kate; Gianfredi, Vincenza; Simondon, Francois; Heijbel, Harald; Danielsson, Niklas; Kramarz, Piotr; Pastore-Celentano, Lucia

    2017-04-27

    Immunisation Information Systems (IIS) are computerised confidential population based-systems containing individual-level information on vaccines received in a given area. They benefit individuals directly by ensuring vaccination according to the schedule and they provide information to vaccine providers and public health authorities responsible for the delivery and monitoring of an immunisation programme. In 2016, the European Centre for Disease Prevention and Control (ECDC) conducted a survey on the level of implementation and functionalities of IIS in 30 European Union/European Economic Area (EU/EEA) countries. It explored the governance and financial support for the systems, IIS software, system characteristics in terms of population, identification of immunisation recipients, vaccinations received, and integration with other health record systems, the use of the systems for surveillance and programme management as well as the challenges involved with implementation. The survey was answered by 27 of the 30 EU/EEA countries having either a system in production at national or subnational levels (n = 16), or being piloted (n = 5) or with plans for setting up a system in the future (n = 6). The results demonstrate the added-value of IIS in a number of areas of vaccination programme monitoring such as monitoring vaccine coverage at local geographical levels, linking individual immunisation history with health outcome data for safety investigations, monitoring vaccine effectiveness and failures and as an educational tool for both vaccine providers and vaccine recipients. IIS represent a significant way forward for life-long vaccination programme monitoring. This article is copyright of The Authors, 2017.

  18. Uncertain added value of Global Trigger Tool for monitoring of patient safety in cancer care

    DEFF Research Database (Denmark)

    Lipczak, Henriette; Neckelmann, Kirsten; Steding-Jessen, Marianne

    2011-01-01

    Monitoring patient safety is a challenging task. The lack of a golden standard has contributed to the recommendation and introduction of several methods. In 2000 the Danish Lung Cancer Registry (DLCR) was established to monitor the clinical management of lung cancer. In 2008 the Global Trigger Tool...... (GTT) was recommended in Denmark as a tool for the monitoring of patient safety. Ideally, the recommendation of a new tool should be preceded by a critical assessment of its added value....

  19. Can individualized weight monitoring using the HeartPhone algorithm improve sensitivity for clinical deterioration of heart failure?

    LENUS (Irish Health Repository)

    Ledwidge, Mark T

    2013-04-01

    Previous studies have demonstrated poor sensitivity of guideline weight monitoring in predicting clinical deterioration of heart failure (HF). This study aimed to evaluate patterns of remotely transmitted daily weights in a high-risk HF population and also to compare guideline weight monitoring and an individualized weight monitoring algorithm.

  20. Construct validity of the Heart Failure Screening Tool (Heart-FaST) to identify heart failure patients at risk of poor self-care: Rasch analysis.

    Science.gov (United States)

    Reynolds, Nicholas A; Ski, Chantal F; McEvedy, Samantha M; Thompson, David R; Cameron, Jan

    2018-02-14

    The aim of this study was to psychometrically evaluate the Heart Failure Screening Tool (Heart-FaST) via: (1) examination of internal construct validity; (2) testing of scale function in accordance with design; and (3) recommendation for change/s, if items are not well adjusted, to improve psychometric credential. Self-care is vital to the management of heart failure. The Heart-FaST may provide a prospective assessment of risk, regarding the likelihood that patients with heart failure will engage in self-care. Psychometric validation of the Heart-FaST using Rasch analysis. The Heart-FaST was administered to 135 patients (median age = 68, IQR = 59-78 years; 105 males) enrolled in a multidisciplinary heart failure management program. The Heart-FaST is a nurse-administered tool for screening patients with HF at risk of poor self-care. A Rasch analysis of responses was conducted which tested data against Rasch model expectations, including whether items serve as unbiased, non-redundant indicators of risk and measure a single construct and that rating scales operate as intended. The results showed that data met Rasch model expectations after rescoring or deleting items due to poor discrimination, disordered thresholds, differential item functioning, or response dependence. There was no evidence of multidimensionality which supports the use of total scores from Heart-FaST as indicators of risk. Aggregate scores from this modified screening tool rank heart failure patients according to their "risk of poor self-care" demonstrating that the Heart-FaST items constitute a meaningful scale to identify heart failure patients at risk of poor engagement in heart failure self-care. © 2018 John Wiley & Sons Ltd.

  1. Attitudes of heart failure patients and health care providers towards mobile phone-based remote monitoring.

    Science.gov (United States)

    Seto, Emily; Leonard, Kevin J; Masino, Caterina; Cafazzo, Joseph A; Barnsley, Jan; Ross, Heather J

    2010-11-29

    Mobile phone-based remote patient monitoring systems have been proposed for heart failure management because they are relatively inexpensive and enable patients to be monitored anywhere. However, little is known about whether patients and their health care providers are willing and able to use this technology. The objective of our study was to assess the attitudes of heart failure patients and their health care providers from a heart function clinic in a large urban teaching hospital toward the use of mobile phone-based remote monitoring. A questionnaire regarding attitudes toward home monitoring and technology was administered to 100 heart failure patients (94/100 returned a completed questionnaire). Semi-structured interviews were also conducted with 20 heart failure patients and 16 clinicians to determine the perceived benefits and barriers to using mobile phone-based remote monitoring, as well as their willingness and ability to use the technology. The survey results indicated that the patients were very comfortable using mobile phones (mean rating 4.5, SD 0.6, on a five-point Likert scale), even more so than with using computers (mean 4.1, SD 1.1). The difference in comfort level between mobile phones and computers was statistically significant (Pmobile phones to view health information (mean 4.4, SD 0.9). Patients and clinicians were willing to use the system as long as several conditions were met, including providing a system that was easy to use with clear tangible benefits, maintaining good patient-provider communication, and not increasing clinical workload. Clinicians cited several barriers to implementation of such a system, including lack of remuneration for telephone interactions with patients and medicolegal implications. Patients and clinicians want to use mobile phone-based remote monitoring and believe that they would be able to use the technology. However, they have several reservations, such as potential increased clinical workload, medicolegal

  2. Analysis on machine tool systems using spindle vibration monitoring for automatic tool changer

    Directory of Open Access Journals (Sweden)

    Shang-Liang Chen

    2015-12-01

    Full Text Available Recently, the intelligent systems of technology have become one of the major items in the development of machine tools. One crucial technology is the machinery status monitoring function, which is required for abnormal warnings and the improvement of cutting efficiency. During processing, the mobility act of the spindle unit determines the most frequent and important part such as automatic tool changer. The vibration detection system includes the development of hardware and software, such as vibration meter, signal acquisition card, data processing platform, and machine control program. Meanwhile, based on the difference between the mechanical configuration and the desired characteristics, it is difficult for a vibration detection system to directly choose the commercially available kits. For this reason, it was also selected as an item for self-development research, along with the exploration of a significant parametric study that is sufficient to represent the machine characteristics and states. However, we also launched the development of functional parts of the system simultaneously. Finally, we entered the conditions and the parameters generated from both the states and the characteristics into the developed system to verify its feasibility.

  3. Geospatial climate monitoring products: Tools for food security assessment

    Science.gov (United States)

    Verdin, James Patrick

    Many of the 250 million people living in the drylands of Sub-Saharan Africa are food insecure---they lack access at all times to enough food for an active and healthy life. Their vulnerability is due in large measure to highly variable climatic conditions and a dependence on rainfed agriculture. Famine, the most extreme food security emergency, is caused by crop failure due to bad weather, conflict, or both. Famine is a slow onset disaster, culminating after two or more bad growing seasons. After the disastrous African famines of the 1970s and 1980s, the U.S. established the Famine Early Warning System (FEWS) to make the observations of climatic and socioeconomic variables needed for early detection of food security emergencies. Two geospatial climate monitoring products, rainfall estimate and vegetation index images derived from satellite data, are operationally used by FEWS analysts. This dissertation describes research to derive new products from them to reduce ambiguity and improve the link between early warning and early response. First, rainfall estimate images were used in a geospatial crop water accounting scheme. The resulting water requirement satisfaction index was used to estimate crop yield, and a correlation of 0.80 with conventional yield reports was obtained for the 1997 maize harvest in Zimbabwe. Thus, the agricultural significance of remotely sensed patterns of precipitation in time and space was made more clear. The second product tested was the expression of a seasonal climate forecast as a series of vegetation index anomaly images. Correlations between sea surface temperature anomalies in the equatorial Pacific and vegetation index anomalies in Southern Africa were established and predictive relationships cross-validated. Using model forecast values of Pacific sea surface temperature from the National Oceanic and Atmospheric Administration for January, February, and March, forecast images of vegetation index anomalies were prepared prior to the

  4. CISN ShakeAlert Earthquake Early Warning System Monitoring Tools

    Science.gov (United States)

    Henson, I. H.; Allen, R. M.; Neuhauser, D. S.

    2015-12-01

    CISN ShakeAlert is a prototype earthquake early warning system being developed and tested by the California Integrated Seismic Network. The system has recently been expanded to support redundant data processing and communications. It now runs on six machines at three locations with ten Apache ActiveMQ message brokers linking together 18 waveform processors, 12 event association processes and 4 Decision Module alert processes. The system ingests waveform data from about 500 stations and generates many thousands of triggers per day, from which a small portion produce earthquake alerts. We have developed interactive web browser system-monitoring tools that display near real time state-of-health and performance information. This includes station availability, trigger statistics, communication and alert latencies. Connections to regional earthquake catalogs provide a rapid assessment of the Decision Module hypocenter accuracy. Historical performance can be evaluated, including statistics for hypocenter and origin time accuracy and alert time latencies for different time periods, magnitude ranges and geographic regions. For the ElarmS event associator, individual earthquake processing histories can be examined, including details of the transmission and processing latencies associated with individual P-wave triggers. Individual station trigger and latency statistics are available. Detailed information about the ElarmS trigger association process for both alerted events and rejected events is also available. The Google Web Toolkit and Map API have been used to develop interactive web pages that link tabular and geographic information. Statistical analysis is provided by the R-Statistics System linked to a PostgreSQL database.

  5. Application of cleaner production tools and failure modes and effects analysis in pig slaughterhourses

    Directory of Open Access Journals (Sweden)

    J. M. Fonseca

    2017-07-01

    Full Text Available Cleaner production programs (CP and Failure Modes and Effects Analysis (FMEA are tools used to improve the sustainability of industries, ensuring greater profitability, quality, reliability and safety of their products and services. The meat industry is among the most polluting industries because of the large amounts of organic waste produced during meat processing. The objective of this study was to combine the CP and FMEA tools and to apply them in a pig slaughterhouse in order to detect critical points along the production chain that have a major environmental impact and to establish corrective and preventive actions that could minimize these problems. The results showed that water is the most consumed resource by the industry and also the main producer of waste due to microbiological contamination with animal feces and blood and meat residues. All impacts were found to be real due to their daily occurrence in the industry. Their severity, occurrence, detection and coverage were classified as moderate and high, high, low and moderate, and moderate and high, respectively. The application of the CP and FMEA tools was efficient in identifying and evaluating the environmental impacts caused by the slaughter and processing of pork carcasses. Liquid slaughter effluents and solid wastes (blood and bones are the factors that pose the greatest risks to the environment. The substitution of treatment plant chemicals with decomposing microorganisms, composting, and the production of animal meal and feed from solid waste are appropriate measures the industry could adopt to minimize the contamination of water resources and soil.

  6. An open system approach to change detection and failure monitoring of complex plants: the NPP experience

    International Nuclear Information System (INIS)

    Kiss, J.; Bokor, J.; Edelmayer, A.; Soumelidis, A.

    1996-01-01

    Along the lines of the recent developments of the diagnostic information system (DIS) in the Nuclear Power Plant Co., Paks, Hungary, in this paper the concept and main features of the system is discussed. DIS is a plant-wide failure monitoring and diagnosis assistance system, whose computational framework is based on distributed computational and diagnostic information resources ensuring fast information retrieval thus considerably improving the availability of diagnostic data in the organization. Main functional constituents of DIS include reactor and primary loops diagnostic, in-core diagnostic and turbine diagnostic subsystems. Experimental leakage detection and loose part monitoring are also part of the system. Advances networking technology makes the integration of inhomogeneous computing technologies to the architecture possible. The idea can play invaluable role in developing next generations of large-scale diagnosis assistance systems and applies directly to surveillance and failure monitoring of the VVER-440 type pressurized water reactor units and to their main components in the plant, enhancing operational safety and reliability. (authors)

  7. ATLAS Distributed Computing Monitoring tools during the LHC Run I

    CERN Document Server

    Schovancova, J; The ATLAS collaboration; Di Girolamo, A; Jezequel, S; Ueda, I; Wenaus, T

    2014-01-01

    This contribution summarizes evolution of the ATLAS Distributed Computing (ADC) Monitoring project during the LHC Run I. The ADC Monitoring targets at the three groups of customers: ADC Operations team to early identify malfunctions and escalate issues to an activity or a service expert, ATLAS national contacts and sites for the real-time monitoring and long-term measurement of the performance of the provided computing resources, and the ATLAS Management for long-term trends and accounting information about the ATLAS Distributed Computing resources.\\\\ During the LHC Run I a significant development effort has been invested in standardization of the monitoring and accounting applications in order to provide extensive monitoring and accounting suite. ADC Monitoring applications separate the data layer and the visualization layer. The data layer exposes data in a predefined format. The visualization layer is designed bearing in mind visual identity of the provided graphical elements, and re-usability of the visua...

  8. ATLAS Distributed Computing Monitoring tools during the LHC Run I

    CERN Document Server

    Schovancova, J; The ATLAS collaboration; Di Girolamo, A; Jezequel, S; Ueda, I; Wenaus, T

    2013-01-01

    This contribution summarizes evolution of the ATLAS Distributed Computing (ADC) Monitoring project during the LHC Run I. The ADC Monitoring targets at the three groups of customers: ADC Operations team to early identify malfunctions and escalate issues to an activity or a service expert, ATLAS national contacts and sites for the real-time monitoring and long-term measurement of the performance of the provided computing resources, and the ATLAS Management for long-term trends and accounting information about the ATLAS Distributed Computing resources.\\\\ During the LHC Run I a significant development effort has been invested in standardization of the monitoring and accounting applications in order to provide extensive monitoring and accounting suite. ADC Monitoring applications separate the data layer and the visualization layer. The data layer exposes data in a predefined format. The visualization layer is designed bearing in mind visual identity of the provided graphical elements, and re-usability of the visua...

  9. Motivational Monitoring as a Tool of Managing Fluctuation of Personnel

    OpenAIRE

    Darchenko Nataliya D.

    2013-01-01

    The goal of the article lies in the study of a possibility to manage fluctuation of personnel at a modern enterprise through application of the motivational monitoring and in identification of some methodical aspects of formation of the system of monitoring the fluctuation of personnel. The article considers the essence, tasks and main directions of motivational monitoring at an enterprise and offers its classification. It proves urgency of the problem of fluctuation of personnel at enterpris...

  10. NASA Prototype All Composite Tank Cryogenic Pressure Tests to Failure with Structural Health Monitoring

    Science.gov (United States)

    Werlink, Rudolph J.; Pena, Francisco

    2015-01-01

    This Paper will describe the results of pressurization to failure of 100 gallon composite tanks using liquid nitrogen. Advanced methods of health monitoring will be compared as will the experimental data to a finite element model. The testing is wholly under NASA including unique PZT (Lead Zirconate Titanate) based active vibration technology. Other technologies include fiber optics strain based systems including NASA AFRC technology, Acoustic Emission, Acellent smart sensor, this work is expected to lead to a practical in-Sutu system for composite tanks.

  11. CEP biomarkers as potential tools for monitoring therapeutics.

    Directory of Open Access Journals (Sweden)

    Kutralanathan Renganathan

    Full Text Available Carboxyethylpyrrole (CEP adducts are oxidative modifications derived from docosahexaenoate-containing lipids that are elevated in ocular tissues and plasma in age-related macular degeneration (AMD and in rodents exposed to intense light. The goal of this study was to determine whether light-induced CEP adducts and autoantibodies are modulated by pretreatment with AL-8309A under conditions that prevent photo-oxidative damage of rat retina. AL-8309A is a serotonin 5-HT1A receptor agonist.Albino rats were dark adapted prior to blue light exposure. Control rats were maintained in normal cyclic light. Rats were injected subcutaneously 3x with 10 mg/kg AL-8309A (2 days, 1 day and 0 hours before light exposure for 6 h (3.1 mW/cm(2, λ=450 nm. Animals were sacrificed immediately following light exposure and eyes, retinas and plasma were collected. CEP adducts and autoantibodies were quantified by Western analysis or ELISA.ANOVA supported significant differences in mean amounts of CEP adducts and autoantibodies among the light + vehicle, light + drug and dark control groups from both retina and plasma. Light-induced CEP adducts in retina were reduced ~20% following pretreatment with AL-8309A (n = 62 rats, p = 0.006 and retinal CEP immunoreactivity was less intense by immunohistochemistry. Plasma levels of light-induced CEP adducts were reduced at least 30% (n = 15 rats, p = 0.004 by drug pretreatment. Following drug treatment, average CEP autoantibody titer in light exposed rats (n = 22 was unchanged from dark control levels, and ~20% (p = 0.046 lower than in vehicle-treated rats.Light-induced CEP adducts in rat retina and plasma were significantly decreased by pretreatment with AL-8309A. These results are consistent with and extend previous studies showing AL-8309A reduces light-induced retinal lesions in rats and support CEP biomarkers as possible tools for monitoring the efficacy of select therapeutics.

  12. Genetic monitoring as a promising tool for conservation and management

    Science.gov (United States)

    Michael K. Schwartz; Gordon Luikart; Robin S. Waples

    2007-01-01

    In response to ever-increasing anthropogenic changes to natural ecosystems, regional, national and international organizations have established guidelines for monitoring biological diversity. Most monitoring programs, however, do not take full advantage of the potential afforded by molecular genetic markers, which can provide information relevant to both ecological and...

  13. Motivational Monitoring as a Tool of Managing Fluctuation of Personnel

    Directory of Open Access Journals (Sweden)

    Darchenko Nataliya D.

    2013-12-01

    Full Text Available The goal of the article lies in the study of a possibility to manage fluctuation of personnel at a modern enterprise through application of the motivational monitoring and in identification of some methodical aspects of formation of the system of monitoring the fluctuation of personnel. The article considers the essence, tasks and main directions of motivational monitoring at an enterprise and offers its classification. It proves urgency of the problem of fluctuation of personnel at enterprises of the country and a possibility of its management through application of the motivational monitoring. It offers methodical principles of monitoring of fluctuation of personnel of an enterprise. It provides results of application of the motivational monitoring in managerial practice of a real enterprise for analysis and study of fluctuation of personnel, which show that monitoring of fluctuation of personnel, development and introduction on its basis of the programme of management of fluctuation of personnel, improvement of the motivational mechanism of management of an enterprise would allow increase of business efficiency, introduce the proactive practice with respect to the personnel, and become a more attractive employer in the labour market. The direction of further studies is development and improvement of organisational and technical aspects of the motivational monitoring and development of recommendations on application of its results with the aim of development of the motivational mechanism that exists at an enterprise.

  14. A web application for self-monitoring improves symptoms in chronic systolic heart failure.

    Science.gov (United States)

    Dorsch, Michael P; Farris, Karen B; Bleske, Barry E; Koelling, Todd M

    2015-04-01

    The objective of this study was to determine if a Web application that promoted mindfulness of the progress of the chronic disease through self-monitoring improved quality of life in heart failure. This was a prospective single-center single-group study. Participants were instructed how to use the Web application and to perform self-monitoring daily for 12 weeks. A comprehensive physical exam, assessment of New York Heart Association (NYHA) class, the Minnesota Living with Heart Failure Questionnaire (MLHFQ), and an evaluation of self-management were performed in person at baseline and at 12 weeks. Participants consisted of older (mean, 59 years), predominantly female (63%) adults with NYHA class II or III symptoms. NYHA classification (preintervention versus postintervention, 2.5±0.13 versus 2.0±0.13; p=0.0032) and MLHFQ score (55.7±4.6 versus 42.6±5.1, respectively; p=0.0078) improved over 12 weeks of self-monitoring. A trend toward improvement was also demonstrated in weight (preintervention versus postintervention, 209±9.6 pounds versus 207±9.4 pounds; by paired t test, p=0.389), number of times exercised per week (1.29±0.5 versus 2.5±0.6, respectively; p=0.3), and walk distance (572±147 yards versus 845±187 yards, respectively; p=0.119). Jugular venous distention (preintervention versus postintervention, 8.1±0.6 cm versus 6.7±0.3 cm; p=0.083) and peripheral edema (29.2% versus 16.7%, respectively; p=0.375) decreased after 12 weeks of self-monitoring via the Web application. A Web application for self-monitoring heart failure over 12 weeks improved both NYHA classification and MLHFQ score. The trend in improved physical activity and physical exam support these outcomes. The number of patients reporting a sodium-restricted diet increased over the 12 weeks, which may have led to the positive findings.

  15. Application of Quality Management Tools for Evaluating the Failure Frequency of Cutter-Loader and Plough Mining Systems

    Science.gov (United States)

    Biały, Witold

    2017-06-01

    Failure frequency in the mining process, with a focus on the mining machine, has been presented and illustrated by the example of two coal-mines. Two mining systems have been subjected to analysis: a cutter-loader and a plough system. In order to reduce costs generated by failures, maintenance teams should regularly make sure that the machines are used and operated in a rational and effective way. Such activities will allow downtimes to be reduced, and, in consequence, will increase the effectiveness of a mining plant. The evaluation of mining machines' failure frequency contained in this study has been based on one of the traditional quality management tools - the Pareto chart.

  16. Development of a comprehensive monitoring and auditing tool for ...

    African Journals Online (AJOL)

    The main purpose of the study was to provide DWAF Free State with a strategic tool to evaluate the current status of the sewage pond systems, thereby providing a base line of information from where immediate interceptive actions can be taken. Further- more, the tool will assist in ensuring that strategic environmen-.

  17. Wear monitoring of single point cutting tool using acoustic emission ...

    Indian Academy of Sciences (India)

    This paper examines the flank and crater wear characteristics of coated carbide tool inserts during dry turning of steel workpieces. A brief review of tool wear mechanisms is presented together with new evidence showing that wear of the TiC layer on both flank and rake faces is dominated by discrete plastic deformation, ...

  18. Reducing unidentified MOV failures: An innovative approach to thermal overload monitoring

    International Nuclear Information System (INIS)

    Hill, K.; Watson, M.E.; Ali, H.S.; Schlesinger, R.

    1991-01-01

    Historically the failure of motor-operated valves to actuate on demand has caused plant transients, reduced safety system reliability, and lost plant availability. The typical control and indication circuit design uses thermal overload contacts in the control circuit only. This has been recognized as a significant unidentified valve failure mode that may prevent the valve from performing its safety function when required. Different approaches have been evaluated to alert operations personnel to this thermal overload condition, but no cost-effective solution has provided indication of the thermal overload while maintaining valve position indication. Iowa Electric Light and Power Company's Duane Arnold Energy Center (DAEC) is utilizing a nuclear-qualified thermal overload monitor in valve control and indication circuits. This innovative approach has proven economical as no new cabling or indicating devices are required. Indication is provided using existing valve position indicating lights. The monitor is engineered to provide indication of a thermal overload trip as well as continuous indication of valve position, consistent with Regulatory Guide 1.97 and guidance provided by Generic Letter 89-10

  19. Tools and strategies to monitor the ATLAS online computing farm

    CERN Document Server

    Ballestrero, S; The ATLAS collaboration; Darlea, G L; Dumitru, I; Scannicchio, DA; Twomey, M S; Valsan, M L; Zaytsev, A

    2012-01-01

    In the ATLAS experiment the collection, processing, selection and conveyance of event data from the detector front-end electronics to mass storage is performed by the ATLAS online farm consisting of nearly 3000 PCs with various characteristics. To assure the correct and optimal working conditions the whole online system must be constantly monitored. The monitoring system should be able to check up to 100000 health parameters and provide alerts on a selected subset. In this paper we present the assessment of a new monitoring and alerting system based on Icinga. This is an open source monitoring system derived from Nagios, granting backward compatibility with already known configurations, plugins and add-ons, while providing new features. We also report on the evaluation of different data gathering systems and visualization interfaces.

  20. On-Line Fuel Failure Monitor for Fuel Testing and Monitoring of Gas Cooled Very High Temperature Reactors

    International Nuclear Information System (INIS)

    Hawari, Ayman I.; Bourham, Mohamed A.

    2010-01-01

    Very High Temperature Reactors (VHTR) utilize the TRISO microsphere as the fundamental fuel unit in the core. The TRISO microsphere (∼ 1-mm diameter) is composed of a UO2 kernel surrounded by a porous pyrolytic graphite buffer, an inner pyrolytic graphite layer, a silicon carbide (SiC) coating, and an outer pyrolytic graphite layer. The U-235 enrichment of the fuel is expected to range from 4%-10% (higher enrichments are also being considered). The layer/coating system that surrounds the UO2 kernel acts as the containment and main barrier against the environmental release of radioactivity. To understand better the behavior of this fuel under in-core conditions (e.g., high temperature, intense fast neutron flux, etc.), the US Department of Energy (DOE) is launching a fuel testing program that will take place at the Advanced Test Reactor (ATR) located at Idaho National Laboratory (INL). During this project North Carolina State University (NCSU) researchers will collaborate with INL staff for establishing an optimized system for fuel monitoring for the ATR tests. In addition, it is expected that the developed system and methods will be of general use for fuel failure monitoring in gas cooled VHTRs.

  1. On0Line Fuel Failure Monitor for Fuel Testing and Monitoring of Gas Cooled Very High Temperature Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Ayman I. Hawari; Mohamed A. Bourham

    2010-04-22

    IVery High Temperature Reactors (VHTR) utilize the TRISO microsphere as the fundamental fuel unit in the core. The TRISO microsphere (~ 1- mm diameter) is composed of a UO2 kernel surrounded by a porous pyrolytic graphite buffer, an inner pyrolytic graphite layer, a silicon carbide (SiC) coating, and an outer pyrolytic graphite layer. The U-235 enrichment of the fuel is expected to range from 4% – 10% (higher enrichments are also being considered). The layer/coating system that surrounds the UO2 kernel acts as the containment and main barrier against the environmental release of radioactivity. To understand better the behavior of this fuel under in-core conditions (e.g., high temperature, intense fast neutron flux, etc.), the US Department of Energy (DOE) is launching a fuel testing program that will take place at the Advanced Test Reactor (ATR) located at Idaho National Laboratory (INL). During this project North Carolina State University (NCSU) researchers will collaborate with INL staff for establishing an optimized system for fuel monitoring for the ATR tests. In addition, it is expected that the developed system and methods will be of general use for fuel failure monitoring in gas cooled VHTRs.

  2. A multi-layer monitoring system for clinical management of Congestive Heart Failure.

    Science.gov (United States)

    Guidi, Gabriele; Pollonini, Luca; Dacso, Clifford C; Iadanza, Ernesto

    2015-01-01

    Congestive Heart Failure (CHF) is a serious cardiac condition that brings high risks of urgent hospitalization and death. Remote monitoring systems are well-suited to managing patients suffering from CHF, and can reduce deaths and re-hospitalizations, as shown by the literature, including multiple systematic reviews. The monitoring system proposed in this paper aims at helping CHF stakeholders make appropriate decisions in managing the disease and preventing cardiac events, such as decompensation, which can lead to hospitalization or death. Monitoring activities are stratified into three layers: scheduled visits to a hospital following up on a cardiac event, home monitoring visits by nurses, and patient's self-monitoring performed at home using specialized equipment. Appropriate hardware, desktop and mobile software applications were developed to enable a patient's monitoring by all stakeholders. For the first two layers, we designed and implemented a Decision Support System (DSS) using machine learning (Random Forest algorithm) to predict the number of decompensations per year and to assess the heart failure severity based on a variety of clinical data. For the third layer, custom-designed sensors (the Blue Scale system) for electrocardiogram (EKG), pulse transit times, bio-impedance and weight allowed frequent collection of CHF-related data in the comfort of the patient's home. We also performed a short-term Heart Rate Variability (HRV) analysis on electrocardiograms self-acquired by 15 healthy volunteers and compared the obtained parameters with those of 15 CHF patients from PhysioNet's PhysioBank archives. We report numerical performances of the DSS, calculated as multiclass accuracy, sensitivity and specificity in a 10-fold cross-validation. The obtained average accuracies are: 71.9% in predicting the number of decompensations and 81.3% in severity assessment. The most serious class in severity assessment is detected with good sensitivity and specificity (0

  3. Wear monitoring of single point cutting tool using acoustic emission ...

    Indian Academy of Sciences (India)

    It clearly indicates that the three stages of wear viz., Stage I, where the rate of wear is low, Stage II, where the rate of wear is moderate and. Stage III, where the rate of wear is faster and leading to the termination of tool life. In stage I, 0 to 8.5 min of the machining operation the tool wear is in the range of 0–8.3 μm only.

  4. Actualities and Development of Heavy-Duty CNC Machine Tool Thermal Error Monitoring Technology

    Science.gov (United States)

    Zhou, Zu-De; Gui, Lin; Tan, Yue-Gang; Liu, Ming-Yao; Liu, Yi; Li, Rui-Ya

    2017-09-01

    Thermal error monitoring technology is the key technological support to solve the thermal error problem of heavy-duty CNC (computer numerical control) machine tools. Currently, there are many review literatures introducing the thermal error research of CNC machine tools, but those mainly focus on the thermal issues in small and medium-sized CNC machine tools and seldom introduce thermal error monitoring technologies. This paper gives an overview of the research on the thermal error of CNC machine tools and emphasizes the study of thermal error of the heavy-duty CNC machine tool in three areas. These areas are the causes of thermal error of heavy-duty CNC machine tool and the issues with the temperature monitoring technology and thermal deformation monitoring technology. A new optical measurement technology called the "fiber Bragg grating (FBG) distributed sensing technology" for heavy-duty CNC machine tools is introduced in detail. This technology forms an intelligent sensing and monitoring system for heavy-duty CNC machine tools. This paper fills in the blank of this kind of review articles to guide the development of this industry field and opens up new areas of research on the heavy-duty CNC machine tool thermal error.

  5. REMOTE SENSING TECHNIQUES AS A TOOL FOR ENVIRONMENTAL MONITORING

    Directory of Open Access Journals (Sweden)

    K. Faisal

    2012-07-01

    Full Text Available The disposal of the solid wastes in landfill sites should be properly monitored by analyzing samples from soil, water, and landfill gases within the landfill site. Nevertheless, ground monitoring systems require intensive efforts and cost. Furthermore, ground monitoring may be difficult to be achieved in large geographic extent. Remote sensing technology has been introduced for waste disposal management and monitoring effects of the landfill sites on the environment. In this paper, two case studies are presented in the Trail Road landfill, Ottawa, Canada and the Al-Jleeb landfill, Al-Farwanyah, Kuwait to evaluate the use of multi-temporal remote sensing images to monitor the landfill sites. The work objectives are: 1 to study the usability of multi-temporal Landsat images for landfill site monitoring by studying the land surface temperature (LST in the Trail Road landfill, 2 to investigate the relationship between the LST and the amount of the landfill gas emitted in the Trail Road landfill, and 3 to use the multi-temporal LST images to detect the suspicious dumping areas within the Al-Jleeb landfill site. Free archive of multi-temporal Landsat images are obtained from the USGS EarthExplorer. The Landsat images are then atmospherically corrected and the LST images are derived from the thermal band of the corrected Landsat images. In the Trail Road landfill, the results reveal that the LST of the landfill site is always higher than the air temperature by 10°C in average as well as the surroundings. A correlation is also observed between the recorded emitted methane (CH4 from the ground monitoring stations and the LST derived from the Landsat images. Based on the findings in the Al-Jleeb landfill, five locations are identified as suspicious dumping areas by overlaying the highest LST contours generated from the multi-temporal LST images. The study demonstrates that the use of multi-temporal remote sensing images can provide supplementary

  6. Monitoring the International Standardization Process Theoretical Choices and Methodological Tools

    Directory of Open Access Journals (Sweden)

    Brigitte Juanals

    2012-08-01

    Full Text Available Many organizations are in charge of global security management. This paper outlines and argues for the construction of a theoretical and methodological framework in order to critically assess the new technopolitics currently being developed in the field of global security and which are materialized in standards. The main purpose is to design both a methodology and specific text mining tools to investigate these standards. These tools will be implemented in a platform designed to provide cartographic representations of standards and to assist the navigation of an end-user through a corpus of standards.

  7. The constant failure rate model for fault tree evaluation as a tool for unit protection reliability assessment

    International Nuclear Information System (INIS)

    Vichev, S.; Bogdanov, D.

    2000-01-01

    The purpose of this paper is to introduce the fault tree analysis method as a tool for unit protection reliability estimation. The constant failure rate model applies for making reliability assessment, and especially availability assessment. For that purpose an example for unit primary equipment structure and fault tree example for simplified unit protection system is presented (author)

  8. A Monitoring Tool of Infant and Toddler Movement Skills

    Science.gov (United States)

    Leitschuh, Carol A.; Harring, Jeffrey R.; Dunn, Winnie

    2014-01-01

    Physical activity in infancy is essential for early brain development. Development in the early years is the most rapid at any time during life. Monitoring functional movement skills of infants and toddlers frequently (3-week intervals) and quickly (minutes) produces information on whether development is on track or in need of intervention. To…

  9. Tools for Monitoring Social Media: A Marketing Research Project

    Science.gov (United States)

    Veeck, Ann; Hoger, Beth

    2014-01-01

    Knowledge of how to effectively monitor social media is an increasingly valued marketing research skill. This study tests an approach for adding social media content to an undergraduate marketing research class team project. The revised project maintains the expected objectives and parameters of a traditional research project, while integrating…

  10. Building software tools to help contextualize and interpret monitoring data

    Science.gov (United States)

    Even modest monitoring efforts at landscape scales produce large volumes of data.These are most useful if they can be interpreted relative to land potential or other similar sites. However, for many ecological systems reference conditions may not be defined or are poorly described, which hinders und...

  11. Development of a comprehensive monitoring and auditing tool for ...

    African Journals Online (AJOL)

    An investigation of the current status of municipal sewage pond systems in the Free State region was undertaken to provide the Department of Water Affairs and Forestry (DWAF) Free State Regional Office with a strategic decision support tool to evaluate the current status of sewage pond systems in order to provide ...

  12. INTELLIGENT TOOL CONDITION MONITORING IN HIGH-SPEED ...

    African Journals Online (AJOL)

    MR PRINCE

    designed using Matlab® neural toolbox. Accuracy of model for the prediction of tool wear at dif- ferent wear stages were evaluated based on the Percentage Error (PE) for both roughing and finishing operations. Results showed that, the heavy wear stage (PE = ±5%) was predicted more accurately compared to the light (PE ...

  13. Monitoring burst (M-burst) — A novel framework of failure localization in all-optical mesh networks

    KAUST Repository

    Ali, Mohammed L.

    2011-10-10

    Achieving instantaneous and precise failure localization in all-optical wavelength division multiplexing (WDM) networks has been an attractive feature of network fault management systems, and is particularly important when failure-dependent protection is employed. The paper introduces a novel framework of real-time failure localization in all-optical WDM mesh networks, called monitoring-burst (m-burst), which aims to initiate a graceful compromise between consumed monitoring resources and monitoring delay. Different from any previously reported solution, the proposed m-burst framework has a single monitoring node (MN) which launches optical bursts along a set of pre-defined close-loop routes, called monitoring cycles (m-cycles), to probe the links along the m-cycles. Bursts along different m-cycles are kept non-overlapping through any link of the network. By identifying the lost bursts due to single link failure events only, the MN can unambiguously localize the failed link in at least 3-connected networks. We will justify the feasibility and applicability of the proposed m-burst framework in the scenario of interest. To avoid possible collision among optical bursts launched by the MN, we define the problem of collision-free scheduling and formulate it into an integer linear program (ILP) in order to minimize the monitoring delay. Numerical results demonstrate the effectiveness of the proposed framework and the proposed solution.

  14. Airport Gate Activity Monitoring Tool Suite for Improved Turnaround Prediction, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of this research is to create a suite of tools for monitoring airport gate activities with the objective of improving aircraft turnaround prediction....

  15. Airport Gate Activity Monitoring Tool Suite for Improved Turnaround Prediction, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this research is to create a suite of tools for monitoring airport gate activities with the objective of improving aircraft turnaround. Airport ramp...

  16. SURFmap: A Network Monitoring Tool Based on the Google Maps API

    NARCIS (Netherlands)

    Hofstede, R.J.; Hofstede, R. J.; Fioreze, Tiago

    2009-01-01

    Network monitoring allows network managers to get a better insight in the network traffic transiting in a managed network. In order to make the tasks of a network manager easier, many network monitoring tools are made available for a wide range of purposes (e.g., traffic accounting, performance

  17. Uncertain added value of Global Trigger Tool for monitoring of patient safety in cancer care

    DEFF Research Database (Denmark)

    Lipczak, Henriette; Neckelmann, Kirsten; Steding-Jessen, Marianne

    2011-01-01

    Monitoring patient safety is a challenging task. The lack of a golden standard has contributed to the recommendation and introduction of several methods. In 2000 the Danish Lung Cancer Registry (DLCR) was established to monitor the clinical management of lung cancer. In 2008 the Global Trigger Tool...

  18. Future Issues and Approaches to Health Monitoring and Failure Prevention for Oil-Free Gas Turbines

    Science.gov (United States)

    DellaCorte, Christopher

    2004-01-01

    Recent technology advances in foil air bearings, high temperature solid lubricants and computer based modeling has enabled the development of small Oil-Free gas turbines. These turbomachines are currently commercialized as small (<100 kW) microturbine generators and larger machines are being developed. Based upon these successes and the high potential payoffs offered by Oil-Free systems, NASA, industry, and other government entities are anticipating Oil-Free gas turbine propulsion systems to proliferate future markets. Since an Oil-Free engine has no oil system, traditional approaches to health monitoring and diagnostics, such as chip detection, oil analysis, and possibly vibration signature analyses (e.g., ball pass frequency) will be unavailable. As such, new approaches will need to be considered. These could include shaft orbit analyses, foil bearing temperature measurements, embedded wear sensors and start-up/coast down speed analysis. In addition, novel, as yet undeveloped techniques may emerge based upon concurrent developments in MEMS technology. This paper introduces Oil-Free technology, reviews the current state of the art and potential for future turbomachinery applications and discusses possible approaches to health monitoring, diagnostics and failure prevention.

  19. Failure mode analysis of preliminary design of ITER divertor impurity monitor

    International Nuclear Information System (INIS)

    Kitazawa, Sin-iti; Ogawa, Hiroaki

    2016-01-01

    Highlights: • Divertor impurity influx monitor for ITER (DIM) is procured by JADA. • DIM is designed to observe light from nuclear fusion plasma directly. • DIM is under preliminary design phase. • Failure mode of DIM was prepared for RAMI analysis. • RAMI analysis on DIM was performed to reduce technical risks. - Abstract: The objective of the divertor impurity influx monitor (DIM) for ITER is to measure the parameters of impurities and hydrogen isotopes (tritium, deuterium, and hydrogen) in divertor plasma using visible and UV spectroscopic techniques in the 200–1000 nm wavelength range. In ITER, special provisions are required to ensure accuracy and full functionality of the diagnostic components under harsh conditions (high temperature, high magnetic field, high vacuum condition, and high radiation field). Japan Domestic Agency is preparing the preliminary design of the ITER DIM system, which will be installed in the upper, equatorial and lower ports. The optical and mechanical designs of the DIM are conducted to fit ITER’s requirements. The optical and mechanical designs meet the requirements of spatial resolution. Some auxiliary systems were examined via prototyping. The preliminary design of the ITER DIM system was evaluated by RAMI analysis. The availability of the designed system is adequately high to satisfy the project requirements. However, some equipment does not have certain designs, and this may cause potential technical risks. The preliminary design should be modified to reduce technical risks and to prepare the final design.

  20. Failure mode analysis of preliminary design of ITER divertor impurity monitor

    Energy Technology Data Exchange (ETDEWEB)

    Kitazawa, Sin-iti, E-mail: kitazawa.siniti@qst.go.jp; Ogawa, Hiroaki

    2016-11-15

    Highlights: • Divertor impurity influx monitor for ITER (DIM) is procured by JADA. • DIM is designed to observe light from nuclear fusion plasma directly. • DIM is under preliminary design phase. • Failure mode of DIM was prepared for RAMI analysis. • RAMI analysis on DIM was performed to reduce technical risks. - Abstract: The objective of the divertor impurity influx monitor (DIM) for ITER is to measure the parameters of impurities and hydrogen isotopes (tritium, deuterium, and hydrogen) in divertor plasma using visible and UV spectroscopic techniques in the 200–1000 nm wavelength range. In ITER, special provisions are required to ensure accuracy and full functionality of the diagnostic components under harsh conditions (high temperature, high magnetic field, high vacuum condition, and high radiation field). Japan Domestic Agency is preparing the preliminary design of the ITER DIM system, which will be installed in the upper, equatorial and lower ports. The optical and mechanical designs of the DIM are conducted to fit ITER’s requirements. The optical and mechanical designs meet the requirements of spatial resolution. Some auxiliary systems were examined via prototyping. The preliminary design of the ITER DIM system was evaluated by RAMI analysis. The availability of the designed system is adequately high to satisfy the project requirements. However, some equipment does not have certain designs, and this may cause potential technical risks. The preliminary design should be modified to reduce technical risks and to prepare the final design.

  1. Upgrade and integration of the configuration and monitoring tools for the ATLAS Online farm

    CERN Document Server

    Ballestrero, S; The ATLAS collaboration; Darlea, G L; Dumitru, I; Scannicchio, DA; Twomey, M S; Valsan, M L; Zaytsev, A

    2012-01-01

    The ATLAS Online farm is a non-homogeneous cluster of nearly 3000 PCs which run the data acquisition, trigger and control of the ATLAS detector. The systems are configured and monitored by a combination of open-source tools, such as Quattor and Nagios, and tools developed in-house, such as ConfDB. We report on the ongoing introduction of new provisioning and configuration tools, Puppet and ConfDB v2 which are more flexible and allow automation for previously uncovered needs, and on the upgrade and integration of the monitoring and alerting tools, including the interfacing of these with the TDAQ Shifter Assistant software and their integration with configuration tools. We discuss the selection of the tools and the assessment of their functionality and performance, and how they enabled the introduction of virtualization for selected services.

  2. Upgrade and integration of the configuration and monitoring tools for the ATLAS Online farm

    International Nuclear Information System (INIS)

    Ballestrero, S; Darlea, G–L; Twomey, M S; Brasolin, F; Dumitru, I; Valsan, M L; Scannicchio, D A; Zaytsev, A

    2012-01-01

    The ATLAS Online farm is a non-homogeneous cluster of nearly 3000 systems which run the data acquisition, trigger and control of the ATLAS detector. The systems are configured and monitored by a combination of open-source tools, such as Quattor and Nagios, and tools developed in-house, such as ConfDB. We report on the ongoing introduction of new provisioning and configuration tools, Puppet and ConfDB v2, which are more flexible and allow automation for previously uncovered needs, and on the upgrade and integration of the monitoring and alerting tools, including the interfacing of these with the TDAQ Shifter Assistant software and their integration with configuration tools. We discuss the selection of the tools and the assessment of their functionality and performance, and how they enabled the introduction of virtualization for selected services.

  3. Dose record keeping: a multi purpose tool in individual monitoring

    International Nuclear Information System (INIS)

    Bermann, F.; Julius, H.W.

    1993-01-01

    Proper recording of radiation doses is an essential part of the process of individual monitoring and shares in the same objective. A dose record keeping system is more than just a computer based data storage system and should rather be a Dose Registration and Information System (DRIS). Objectives of dose record keeping are given. As a result of the integration of member states of the European Communities, co-operation and exchange of personnel between countries will be increasing. This will probably require national dose registration systems and adequate data communication between them. These developments emphasize the necessity for international harmonization of dose record keeping systems and categorization of the data they contain. General characteristics and specific aspects of dose record keeping systems will be dealt with. Attention will also be given to some special applications of the recorded information, such as: the use of data for epidemiological studies and for QA purposes. (authors). 5 tabs., 4 refs

  4. UAV – a useful tool for monitoring woodlands

    Directory of Open Access Journals (Sweden)

    Zmarz Anna

    2014-06-01

    Full Text Available Unmanned aerial systems are in many countries one of the most dynamically developing branches of technology. They have also been recognized and are being utilized by scientists who find remote sensing indispensable in their work. Today, it is increasingly common to find research teams utilizing so-called drones in field research. Unmanned systems are becoming ever more important for environment monitoring by, on the one hand, providing data from inaccessible or remote areas, and, on the other hand, reducing the human costs required by traditional large field teams while also increasing the efficiency of the work. This paper presents the possibility of utilizing UAVs for image data collection in woodland areas.

  5. Brain Multimodality Monitoring: A New Tool in Neurocritical Care of Comatose Patients

    Directory of Open Access Journals (Sweden)

    Nudrat Tasneem

    2017-01-01

    Full Text Available Neurocritical care patients are at risk of developing secondary brain injury from inflammation, ischemia, and edema that follows the primary insult. Recognizing clinical deterioration due to secondary injury is frequently challenging in comatose patients. Multimodality monitoring (MMM encompasses various tools to monitor cerebral metabolism, perfusion, and oxygenation aimed at detecting these changes to help modify therapies before irreversible injury sets in. These tools include intracranial pressure (ICP monitors, transcranial Doppler (TCD, Hemedex™ (thermal diffusion probe used to measure regional cerebral blood flow, microdialysis catheter (used to measure cerebral metabolism, Licox™ (probe used to measure regional brain tissue oxygen tension, and continuous electroencephalography. Although further research is needed to demonstrate their impact on improving clinical outcomes, their contribution to illuminate the black box of the brain in comatose patients is indisputable. In this review, we further elaborate on commonly used MMM parameters, tools used to measure them, and the indications for monitoring per current consensus guidelines.

  6. A software tool for design of process monitoring and analysis systems

    DEFF Research Database (Denmark)

    Singh, Ravendra; Gernaey, Krist; Gani, Rafiqul

    2009-01-01

    A well designed process monitoring and analysis system is necessary to consistently achieve any predefined end product quality. Systematic computer aided methods and tools provide the means to design the necessary process monitoring and analysis systems and/or to validate any existing monitoring...... and analysis system. A software to achieve this has been developed. Two developed supporting tools for the design, a knowledge base (consisting of the process knowledge as well as the knowledge on measurement methods & tools) and a model library (consisting of the process operational models) have been extended...... rigorously and integrated with the user interface, which made the software more generic and applicable to a wide range of problems. The software for the design of a process monitoring and analysis system is presented and illustrated with a tablet manufacturing process example....

  7. Heart failure - tests

    Science.gov (United States)

    CHF - tests; Congestive heart failure - tests; Cardiomyopathy - tests; HF - tests ... best test to: Identify which type of heart failure (systolic, diastolic, valvular) Monitor your heart failure and ...

  8. DNA Sequencing as a Tool to Monitor Marine Ecological Status

    Directory of Open Access Journals (Sweden)

    Kelly D. Goodwin

    2017-05-01

    Full Text Available Many ocean policies mandate integrated, ecosystem-based approaches to marine monitoring, driving a global need for efficient, low-cost bioindicators of marine ecological quality. Most traditional methods to assess biological quality rely on specialized expertise to provide visual identification of a limited set of specific taxonomic groups, a time-consuming process that can provide a narrow view of ecological status. In addition, microbial assemblages drive food webs but are not amenable to visual inspection and thus are largely excluded from detailed inventory. Molecular-based assessments of biodiversity and ecosystem function offer advantages over traditional methods and are increasingly being generated for a suite of taxa using a “microbes to mammals” or “barcodes to biomes” approach. Progress in these efforts coupled with continued improvements in high-throughput sequencing and bioinformatics pave the way for sequence data to be employed in formal integrated ecosystem evaluation, including food web assessments, as called for in the European Union Marine Strategy Framework Directive. DNA sequencing of bioindicators, both traditional (e.g., benthic macroinvertebrates, ichthyoplankton and emerging (e.g., microbial assemblages, fish via eDNA, promises to improve assessment of marine biological quality by increasing the breadth, depth, and throughput of information and by reducing costs and reliance on specialized taxonomic expertise.

  9. Tools for Developing a Quality Management Program: Proactive Tools (Process Mapping, Value Stream Mapping, Fault Tree Analysis, and Failure Mode and Effects Analysis)

    International Nuclear Information System (INIS)

    Rath, Frank

    2008-01-01

    This article examines the concepts of quality management (QM) and quality assurance (QA), as well as the current state of QM and QA practices in radiotherapy. A systematic approach incorporating a series of industrial engineering-based tools is proposed, which can be applied in health care organizations proactively to improve process outcomes, reduce risk and/or improve patient safety, improve through-put, and reduce cost. This tool set includes process mapping and process flowcharting, failure modes and effects analysis (FMEA), value stream mapping, and fault tree analysis (FTA). Many health care organizations do not have experience in applying these tools and therefore do not understand how and when to use them. As a result there are many misconceptions about how to use these tools, and they are often incorrectly applied. This article describes these industrial engineering-based tools and also how to use them, when they should be used (and not used), and the intended purposes for their use. In addition the strengths and weaknesses of each of these tools are described, and examples are given to demonstrate the application of these tools in health care settings

  10. Post-discharge heart failure monitoring program in Turkey: Hit-PoinT

    Science.gov (United States)

    Çavuşoğlu, Yüksel; Zoghi, Mehdi; Eren, Mehmet; Bozçalı, Evin; Kozdağ, Güliz; Şentürk, Tunay; Alicik, Güray; Soylu, Korhan; Sarı, İbrahim; Berilgen, Rida; Temizhan, Ahmet; Gencer, Erkan; Orhan, Ahmet Lütfü; Polat, Veli; Kaderli, Aysel Aydın; Aktoz, Meryem; Zengin, Halit; Aksoy, Mehmet; Selçuk, Mehmet Timur; Ergene, Oktay; Soran, Özlem

    2017-01-01

    Objective: The aim of this study was to assess the efficacy and feasibility of an enhanced heart failure (HF) education with a 6-month telephone follow- up program in post-discharge ambulatory HF patients. Methods: The Hit-Point trial was a multicenter, randomized, controlled trial of enhanced HF education with a 6-month telephone follow-up program (EHFP) vs routine care (RC) in patients with HF and reduced ejection fraction. A total of 248 patients from 10 centers in various geographical areas were randomized: 125 to EHFP and 123 to RC. Education included information on adherence to treatment, symptom recognition, diet and fluid intake, weight monitoring, activity and exercise training. Patients were contacted by telephone after 1, 3, and 6 months. The primary study endpoint was cardiovascular death. Results: Although all-cause mortality didn’t differ between the EHFP and RC groups (p=NS), the percentage of cardiovascular deaths in the EHFP group was significantly lower than in the RC group at the 6-month follow up (5.6% vs. 8.9%, p=0.04). The median number of emergency room visits was one and the median number of all cause hospitalizations and heart failure hospitalizations were zero. Twenty-tree percent of the EHFP group and 35% of the RC group had more than a median number of emergency room visits (p=0.05). There was no significant difference regarding the median number of all–cause or heart failure hospitalizations. At baseline, 60% of patients in EHFP and 61% in RC were in NYHA Class III or IV, while at the 6-month follow up only 12% in EHFP and 32% in RC were in NYHA Class III or IV (p=0.001). Conclusion: These results demonstrate the potential clinical benefits of an enhanced HF education and follow up program led by a cardiologist in reducing cardiovascular deaths and number of emergency room visits with an improvement in functional capacity at 6 months in post-discharge ambulatory HF patients. PMID:27488754

  11. Cost effective tools for soil organic carbon monitoring

    Science.gov (United States)

    Shepherd, Keith; Aynekulu, Ermias

    2013-04-01

    There is increasing demand for data on soil properties at fine spatial resolution to support management and planning decisions. Measurement of soil organic carbon has attracted much interest because (i) soil organic carbon is widely cited as a useful indicator of soil condition and (ii) of the importance of soil carbon in the global carbon cycle and climate mitigation strategies. However in considering soil measurement designs there has been insufficient attention given to careful analysis of the specific decisions that the measurements are meant to support and on what measurements have high information value for decision-making. As a result, much measurement effort may be wasted or focused on the wrong variables. A cost-effective measurement is one that reduces risk in decisions and does not cost more than the societal returns to additional evidence. A key uncertainty in measuring soil carbon as a soil condition indicator is what constitutes a good or bad level of carbon on a given soil. A measure of soil organic carbon concentration may have limited value for informing management decisions without the additional information required to interpret it, and so expending further efforts on improving measurements to increase precision may then have no value to improving the decision. Measuring soil carbon stock changes for carbon trading purposes requires high levels of measurement precision but there is still large uncertainty on whether the costs of measurement exceed the benefits. Since the largest cost component in soil monitoring is often travel to the field and physically sampling soils, it is generally cost-effective to meet multiple objectives by analysing a number of properties on a soil sample. Diffuse reflectance infrared spectroscopy is playing a key role in allowing multiple soil properties to be determined rapidly and at low cost. The method provides estimation of multiple soil properties (e.g. soil carbon, texture and mineralogy) in one measurement

  12. Use of Remote Monitoring to Improve Outcomes in Patients with Heart Failure: A Pilot Trial

    Science.gov (United States)

    Kulshreshtha, Ambar; Kvedar, Joseph C.; Goyal, Abhinav; Halpern, Elkan F.; Watson, Alice J.

    2010-01-01

    Remote monitoring (RM) of homebound heart failure (HF) patients has previously been shown to reduce hospital admissions. We conducted a pilot trial of ambulatory, non-homebound patients recently hospitalized for HF to determine whether RM could be successfully implemented in the ambulatory setting. Eligible patients from Massachusetts General Hospital (n = 150) were randomized to a control group (n = 68) or to a group that was offered RM (n = 82). The participants transmitted vital signs data to a nurse who coordinated care with the physician over the course of the 6-month study. Participants in the RM program had a lower all-cause per person readmission rate (mean = 0.64, SD ± 0.87) compared to the usual care group (mean = 0.73, SD ± 1.51; P-value = .75) although the difference was not statistically significant. HF-related readmission rate was similarly reduced in participants. This pilot study demonstrates that RM can be successfully implemented in non-homebound HF patients and may reduce readmission rates. PMID:20508741

  13. Monitoring and Failure Analysis of Corroded Bridge Cables under Fatigue Loading Using Acoustic Emission Sensors

    Directory of Open Access Journals (Sweden)

    Hui Li

    2012-03-01

    Full Text Available Cables play an important role in cable-stayed systems, but are vulnerable to corrosion and fatigue damage. There is a dearth of studies on the fatigue damage evolution of corroded cable. In the present study, the acoustic emission (AE technology is adopted to monitor the fatigue damage evolution process. First, the relationship between stress and strain is determined through a tensile test for corroded and non-corroded steel wires. Results show that the mechanical performance of corroded cables is changed considerably. The AE characteristic parameters for fatigue damage are then established. AE energy cumulative parameters can accurately describe the fatigue damage evolution of corroded cables. The failure modes in each phase as well as the type of acoustic emission source are determined based on the results of scanning electron microscopy. The waveform characteristics, damage types, and frequency distribution of the corroded cable at different damage phases are collected. Finally, the number of broken wires and breakage time of the cables are determined according to the variation in the margin index.

  14. Force Sensor Based Tool Condition Monitoring Using a Heterogeneous Ensemble Learning Model

    Directory of Open Access Journals (Sweden)

    Guofeng Wang

    2014-11-01

    Full Text Available Tool condition monitoring (TCM plays an important role in improving machining efficiency and guaranteeing workpiece quality. In order to realize reliable recognition of the tool condition, a robust classifier needs to be constructed to depict the relationship between tool wear states and sensory information. However, because of the complexity of the machining process and the uncertainty of the tool wear evolution, it is hard for a single classifier to fit all the collected samples without sacrificing generalization ability. In this paper, heterogeneous ensemble learning is proposed to realize tool condition monitoring in which the support vector machine (SVM, hidden Markov model (HMM and radius basis function (RBF are selected as base classifiers and a stacking ensemble strategy is further used to reflect the relationship between the outputs of these base classifiers and tool wear states. Based on the heterogeneous ensemble learning classifier, an online monitoring system is constructed in which the harmonic features are extracted from force signals and a minimal redundancy and maximal relevance (mRMR algorithm is utilized to select the most prominent features. To verify the effectiveness of the proposed method, a titanium alloy milling experiment was carried out and samples with different tool wear states were collected to build the proposed heterogeneous ensemble learning classifier. Moreover, the homogeneous ensemble learning model and majority voting strategy are also adopted to make a comparison. The analysis and comparison results show that the proposed heterogeneous ensemble learning classifier performs better in both classification accuracy and stability.

  15. Laboratory versus industrial cutting force sensor in tool condition monitoring system

    International Nuclear Information System (INIS)

    Szwajka, K

    2005-01-01

    Research works concerning the utilisation of cutting force measures in tool condition monitoring usually present results and deliberations based on laboratory sensors. These sensors are too fragile to be used in industrial practice. Industrial sensors employed on the factory floor are less accurate, and this must be taken into account when creating a tool condition monitoring strategy. Another drawback of most of these works is that constant cutting parameters are used for the entire tool life. This does not reflect industrial practice where the same tool is used at different feeds and depths of cut in sequential passes. This paper presents a comparison of signals originating from laboratory and industrial cutting force sensors. The usability of the sensor output was studied during a laboratory simulation of industrial cutting conditions. Instead of building mathematical models for the correlation between tool wear and cutting force, an FFBP artificial neural network was used to find which combination of input data would provide an acceptable estimation of tool wear. The results obtained proved that cross talk between channels has an important influence on cutting force measurements, however this input configuration can be used for a tool condition monitoring system

  16. Topological clustering as a tool for planning water quality monitoring in water distribution networks

    DEFF Research Database (Denmark)

    Kirstein, Jonas Kjeld; Albrechtsen, Hans-Jørgen; Rygaard, Martin

    2015-01-01

    identification of potential contamination and affected consumers in contamination cases. Although still in development, the method shows potential for assisting utilities during planning of monitoring programs and as decision support tool during emergency contingency situations.......Topological clustering was explored as a tool for water supply utilities in preparation of monitoring and contamination contingency plans. A complex water distribution network model of Copenhagen, Denmark, was simplified by topological clustering into recognizable water movement patterns to: (1......) identify steady clusters for a part of the network where an actual contamination has occurred; (2) analyze this event by the use of mesh diagrams; and (3) analyze the use of mesh diagrams as a decision support tool for planning water quality monitoring. Initially, the network model was divided...

  17. Artificial intelligence tools decision support systems in condition monitoring and diagnosis

    CERN Document Server

    Galar Pascual, Diego

    2015-01-01

    Artificial Intelligence Tools: Decision Support Systems in Condition Monitoring and Diagnosis discusses various white- and black-box approaches to fault diagnosis in condition monitoring (CM). This indispensable resource: Addresses nearest-neighbor-based, clustering-based, statistical, and information theory-based techniques Considers the merits of each technique as well as the issues associated with real-life application Covers classification methods, from neural networks to Bayesian and support vector machines Proposes fuzzy logic to explain the uncertainties associated with diagnostic processes Provides data sets, sample signals, and MATLAB® code for algorithm testing Artificial Intelligence Tools: Decision Support Systems in Condition Monitoring and Diagnosis delivers a thorough evaluation of the latest AI tools for CM, describing the most common fault diagnosis techniques used and the data acquired when these techniques are applied.

  18. G-REALM: A lake/reservoir monitoring tool for drought monitoring and water resources management.

    Science.gov (United States)

    Birkett, C. M.; Ricko, M.; Beckley, B. D.; Yang, X.; Tetrault, R. L.

    2017-12-01

    G-REALM is a NASA/USDA funded operational program offering water-level products for lakes and reservoirs and these are currently derived from the NASA/CNES Topex/Jason series of satellite radar altimeters. The main stakeholder is the USDA/Foreign Agricultural Service (FAS) though many other end-users utilize the products for a variety of interdisciplinary science and operational programs. The FAS utilize the products within their CropExplorer Decision Support System (DSS) to help assess irrigation potential, and to monitor both short-term (agricultural) and longer-term (hydrological) drought conditions. There is increasing demand for a more global monitoring service that in particular, captures the variations in the smallest (1 to 100km2) reservoirs and water holdings in arid and semi-arid regions. Here, water resources are critical to both agriculture and regional security. A recent G-REALM 10-day resolution product upgrade and expansion has allowed for more accurate lake level products to be released and for a greater number of water bodies to be monitored. The next program phase focuses on the exploration of the enhanced radar altimeter data sets from the Cryosat-2 and Sentinel-3 missions with their improved spatial resolution, and the expansion of the system to the monitoring of 1,000 water bodies across the globe. In addition, a new element, the monitoring of surface water levels in wetland zones, is also being introduced. This aims to satisfy research and stakeholder requirements with respect to programs examining the links between inland fisheries catch potential and declining water levels, and to those monitoring the delicate balance between water resources, agriculture, and fisheries management in arid basins.

  19. Analysis of arrhythmic events is useful to detect lead failure earlier in patients followed by remote monitoring.

    Science.gov (United States)

    Nishii, Nobuhiro; Miyoshi, Akihito; Kubo, Motoki; Miyamoto, Masakazu; Morimoto, Yoshimasa; Kawada, Satoshi; Nakagawa, Koji; Watanabe, Atsuyuki; Nakamura, Kazufumi; Morita, Hiroshi; Ito, Hiroshi

    2018-03-01

    Remote monitoring (RM) has been advocated as the new standard of care for patients with cardiovascular implantable electronic devices (CIEDs). RM has allowed the early detection of adverse clinical events, such as arrhythmia, lead failure, and battery depletion. However, lead failure was often identified only by arrhythmic events, but not impedance abnormalities. To compare the usefulness of arrhythmic events with conventional impedance abnormalities for identifying lead failure in CIED patients followed by RM. CIED patients in 12 hospitals have been followed by the RM center in Okayama University Hospital. All transmitted data have been analyzed and summarized. From April 2009 to March 2016, 1,873 patients have been followed by the RM center. During the mean follow-up period of 775 days, 42 lead failure events (atrial lead 22, right ventricular pacemaker lead 5, implantable cardioverter defibrillator [ICD] lead 15) were detected. The proportion of lead failures detected only by arrhythmic events, which were not detected by conventional impedance abnormalities, was significantly higher than that detected by impedance abnormalities (arrhythmic event 76.2%, 95% CI: 60.5-87.9%; impedance abnormalities 23.8%, 95% CI: 12.1-39.5%). Twenty-seven events (64.7%) were detected without any alert. Of 15 patients with ICD lead failure, none has experienced inappropriate therapy. RM can detect lead failure earlier, before clinical adverse events. However, CIEDs often diagnose lead failure as just arrhythmic events without any warning. Thus, to detect lead failure earlier, careful human analysis of arrhythmic events is useful. © 2017 Wiley Periodicals, Inc.

  20. Monitoring and Control by Virtual Tools of an Educational Renewable Energy System

    Directory of Open Access Journals (Sweden)

    Gligor Adrian

    2009-12-01

    Full Text Available The scope of the present paper is to present the architecture and design of an effective tool useful for monitoring, maintenance and training of specialists in the field of photovoltaic renewable energy Among renewable energy resources, solar energy represents an easy to use, accessible and green source of energy. An important goal is the efficient use of solar energy which can only be achieved by the knowledge of solar datum and equipment characteristics from a studied area. Based on this idea, the paper presents a concept of virtual tools developed on web technologies and virtual instrumentation for monitoring and control of solar renewable energy. These tools are mainly designed as a base for a virtual laboratory that can be used for the study of photovoltaic and thermal solar energy parameters, representing, by didactical point of view, a handful way for students to study the phenomenology and also a training tool for specialists in the field of solar photovoltaic energy.

  1. Moisture monitoring of ferrocyanide tanks: An evaluation of methods and tools

    Energy Technology Data Exchange (ETDEWEB)

    Meacham, J.E.; Babad, H.; Toffer, H.

    1993-04-01

    This report reviews the strengths and limitations of moisture monitoring technologies that could be used for determining moisture concentration in Hanford Site single-shell ferrocyanide waste tanks. Two technologies (neutron diffusion and near-infrared spectroscopy) are being pursued as part of the ferrocyanide program. A third technology, Raman spectroscopy, is in development as a speciation tool at the Westinghouse Hanford Company 222-S Laboratory. The potential application of Raman spectroscopy to moisture monitoring is discussed.

  2. BARC-risk monitor- a tool for operational safety assessment in nuclear power plants

    International Nuclear Information System (INIS)

    Vinod, Gopika; Saraf, R.K.; Babar, A.K.; Hadap, Nikhil

    2000-12-01

    Probabilistic safety assessment has become a key tool as on today to identify and understand nuclear power plant vulnerabilities. As a result of the availability of these PSA studies, there is a desire to use them to enhance plant safety and to operate the nuclear stations in the most efficient manner. Risk monitor is a PC based tool, which computes the real time safety level and assists plant personnel to manage day-to-day activities. Risk monitor is a PC based user friendly software tool used for modification and re-analysis of a nuclear power plant. Operation of risk monitor is based on PSA methods for assisting in day to day applications. Risk monitoring programs can assess the risk profile and are used to optimise the operation of nuclear power plants with respect to a minimum risk level over the operating time. This report presents the background activities of risk monitor, its application areas and also gives the status of such tools in international scenarios. The software is based on the PSA model of Kaiga generating station and would be applicable to similar design configuration. (author)

  3. Next steps in the evolution of GridICE: a monitoring tool for grid systems

    International Nuclear Information System (INIS)

    Andreozzi, S; Fattibene, E; Misurelli, G; Aiftimiei, C; Pra, S D; Fantinel, S; Cuscela, G; Donvito, G; Dudhalkar, V; Maggi, G; Pierro, A

    2008-01-01

    GridICE is a monitoring tool for Grid systems that support the operations and management activities of different types of users: site administrators, VO managers, Grid operators and end-users. The tool is designed to deal with the dynamics, diversity and geographical distribution of the observed resources. It is continuously evolved driven by user requirements. The purpose of this paper is to disseminate the evolution strategy in order to solicit for a community feedback

  4. Multiple sensor monitoring in nickel alloy turning for tool wear assessment via sensor fusion

    OpenAIRE

    Segreto, T.; Simeone, A.; Teti, R.

    2013-01-01

    A multiple sensor monitoring system comprising cutting force, acoustic emission and vibration sensing units was employed for tool state assessment during turning of Inconel 718 nickel alloy. Feature extraction was realised by processing the detected sensor signals in order to reduce the high dimensionality of the sensorial data. The extracted features were fused to realise a sensor fusion methodology based on neural network pattern recognition for decision making on tool wear condition.

  5. [Use of lung ultrasound as a prognostic tool in outpatients with heart failure].

    Science.gov (United States)

    Tojo Villanueva, María Del Carmen; Fernández López, María; Canora Lebrato, Jesús; Satué Bartolomé, José Ángel; San Martín Prado, Alberto; Zapatero Gaviria, Antonio

    2016-07-01

    To assess the prognostic value of lung ultrasound for patients with chronic heart failure. Prospective observational cohort study, in which a lung ultrasound was performed on 54 patients at a heart failure outpatient consultation. Ultrasonography was classified as positive or negative for ultrasound interstitial syndrome depending on the number of B lines observed. Patients were followed up for six months; considering emergency visits, readmissions and deaths due to heart failure as markers of poor prognosis. 53.7% (29) of the patients had ultrasound interstitial syndrome. Among them, 48.3% (14) were readmitted, compared to 16% (4) of those without the syndrome (P=.012). Considering any of the events previously described as end points (readmissions, emergencies and deaths), we found that in the group of patients with ultrasound interstitial syndrome, 55.2% (16) had at least one of these complications, compared to 20% (5) of participants without the syndrome (P=.008). Lung ultrasound in the outpatient setting is useful in predicting which patients are at increased risk of heart failure decompensation in the mid-term. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  6. Tool Monitoring and Electronic Event Logging for Sheet Metal Forming Processes

    Directory of Open Access Journals (Sweden)

    Gerd Heiserich

    2010-06-01

    Full Text Available This contribution describes some innovative solutions regarding sensor systems for tool monitoring in the sheet metal industry. Autonomous and tamper-proof sensors, which are integrated in the forming tools, can detect and count the strokes carried out by a sheet metal forming press. Furthermore, an electronic event logger for documentary purposes and quality control was developed. Based on this technical solution, new business models such as leasing of sheet metal forming tools can be established for cooperation among enterprises. These models allow usage-based billing for the contractors, taking the effectively produced number of parts into account.

  7. Electronic monitoring of adherence to inhaled corticosteroids: an essential tool in identifying severe asthma in children.

    Science.gov (United States)

    Jochmann, Anja; Artusio, Luca; Jamalzadeh, Angela; Nagakumar, Prasad; Delgado-Eckert, Edgar; Saglani, Sejal; Bush, Andrew; Frey, Urs; Fleming, Louise J

    2017-12-01

    International guidelines recommend that severe asthma can only be diagnosed after contributory factors, including adherence, have been addressed. Accurate assessment of adherence is difficult in clinical practice. We hypothesised that electronic monitoring in children would identify nonadherence, thus delineating the small number with true severe asthma.Asthmatic children already prescribed inhaled corticosteroids were prospectively recruited and persistence of adherence assessed using electronic monitoring devices. Spirometry, airway inflammation and asthma control were measured at the start and end of the monitoring period.93 children (62 male; median age 12.4 years) were monitored for a median of 92 days. Median (range) monitored adherence was 74% (21-99%). We identified four groups: 1) good adherence during monitoring with improved control, 24% (likely previous poor adherence); 2) good adherence with poor control, 18% (severe therapy-resistant asthma); 3) poor adherence with good control, 26% (likely overtreated); and 4) poor adherence with poor control, 32%. No clinical parameter prior to monitoring distinguished these groups.Electronic monitoring is a useful tool for identifying children in whom a step up in treatment is indicated. Different approaches are needed in those who are controlled when adherent or who are nonadherent. Electronic monitoring is essential in a paediatric severe asthma clinic. Copyright ©ERS 2017.

  8. Monitoring Global Food Security with New Remote Sensing Products and Tools

    Science.gov (United States)

    Budde, M. E.; Rowland, J.; Senay, G. B.; Funk, C. C.; Husak, G. J.; Magadzire, T.; Verdin, J. P.

    2012-12-01

    Global agriculture monitoring is a crucial aspect of monitoring food security in the developing world. The Famine Early Warning Systems Network (FEWS NET) has a long history of using remote sensing and crop modeling to address food security threats in the form of drought, floods, pests, and climate change. In recent years, it has become apparent that FEWS NET requires the ability to apply monitoring and modeling frameworks at a global scale to assess potential impacts of foreign production and markets on food security at regional, national, and local levels. Scientists at the U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center and the University of California Santa Barbara (UCSB) Climate Hazards Group have provided new and improved data products as well as visualization and analysis tools in support of the increased mandate for remote monitoring. We present our monitoring products for measuring actual evapotranspiration (ETa), normalized difference vegetation index (NDVI) in a near-real-time mode, and satellite-based rainfall estimates and derivatives. USGS FEWS NET has implemented a Simplified Surface Energy Balance (SSEB) model to produce operational ETa anomalies for Africa and Central Asia. During the growing season, ETa anomalies express surplus or deficit crop water use, which is directly related to crop condition and biomass. We present current operational products and provide supporting validation of the SSEB model. The expedited Moderate Resolution Imaging Spectroradiometer (eMODIS) production system provides FEWS NET with an improved NDVI dataset for crop and rangeland monitoring. eMODIS NDVI provides a reliable data stream with a relatively high spatial resolution (250-m) and short latency period (less than 12 hours) which allows for better operational vegetation monitoring. We provide an overview of these data and cite specific applications for crop monitoring. FEWS NET uses satellite rainfall estimates as inputs for

  9. Reflectance confocal microscopy: an effective tool for monitoring ultraviolet B phototherapy in psoriasis.

    NARCIS (Netherlands)

    Wolberink, E.A.W.; Erp, P.E.J. van; Boer-van Huizen, R.T. de; Kerkhof, P.C.M. van de; Gerritsen, M.J.P.

    2012-01-01

    Background In vivo reflectance confocal microscopy (RCM) is a novel, noninvasive imaging technique which enables imaging of skin at a cellular resolution comparable to conventional microscopy. Objectives We performed a pilot study to evaluate RCM as a noninvasive tool for monitoring ultraviolet (UV)

  10. Web-based monitoring tools for Resistive Plate Chambers in the CMS experiment at CERN

    Science.gov (United States)

    Kim, M. S.; Ban, Y.; Cai, J.; Li, Q.; Liu, S.; Qian, S.; Wang, D.; Xu, Z.; Zhang, F.; Choi, Y.; Kim, D.; Goh, J.; Choi, S.; Hong, B.; Kang, J. W.; Kang, M.; Kwon, J. H.; Lee, K. S.; Lee, S. K.; Park, S. K.; Pant, L. M.; Mohanty, A. K.; Chudasama, R.; Singh, J. B.; Bhatnagar, V.; Mehta, A.; Kumar, R.; Cauwenbergh, S.; Costantini, S.; Cimmino, A.; Crucy, S.; Fagot, A.; Garcia, G.; Ocampo, A.; Poyraz, D.; Salva, S.; Thyssen, F.; Tytgat, M.; Zaganidis, N.; Doninck, W. V.; Cabrera, A.; Chaparro, L.; Gomez, J. P.; Gomez, B.; Sanabria, J. C.; Avila, C.; Ahmad, A.; Muhammad, S.; Shoaib, M.; Hoorani, H.; Awan, I.; Ali, I.; Ahmed, W.; Asghar, M. I.; Shahzad, H.; Sayed, A.; Ibrahim, A.; Aly, S.; Assran, Y.; Radi, A.; Elkafrawy, T.; Sharma, A.; Colafranceschi, S.; Abbrescia, M.; Calabria, C.; Colaleo, A.; Iaselli, G.; Loddo, F.; Maggi, M.; Nuzzo, S.; Pugliese, G.; Radogna, R.; Venditti, R.; Verwilligen, P.; Benussi, L.; Bianco, S.; Piccolo, D.; Paolucci, P.; Buontempo, S.; Cavallo, N.; Merola, M.; Fabozzi, F.; Iorio, O. M.; Braghieri, A.; Montagna, P.; Riccardi, C.; Salvini, P.; Vitulo, P.; Vai, I.; Magnani, A.; Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P.; Aleksandrov, A.; Genchev, V.; Iaydjiev, P.; Rodozov, M.; Sultanov, G.; Vutova, M.; Stoykova, S.; Hadjiiska, R.; Ibargüen, H. S.; Morales, M. I. P.; Bernardino, S. C.; Bagaturia, I.; Tsamalaidze, Z.; Crotty, I.

    2014-10-01

    The Resistive Plate Chambers (RPC) are used in the CMS experiment at the trigger level and also in the standard offline muon reconstruction. In order to guarantee the quality of the data collected and to monitor online the detector performance, a set of tools has been developed in CMS which is heavily used in the RPC system. The Web-based monitoring (WBM) is a set of java servlets that allows users to check the performance of the hardware during data taking, providing distributions and history plots of all the parameters. The functionalities of the RPC WBM monitoring tools are presented along with studies of the detector performance as a function of growing luminosity and environmental conditions that are tracked over time.

  11. Web-based monitoring tools for Resistive Plate Chambers in the CMS experiment at CERN

    CERN Document Server

    Kim, Min Suk

    2014-01-01

    The Resistive Plate Chambers (RPC) are used in the CMS experiment at the trigger level and also in the standard offline muon reconstruction. In order to guarantee the quality of the data collected and to monitor online the detector performance, a set of tools has been developed in CMS which is heavily used in the RPC system. The Web-based monitoring (WBM) is a set of java servlets that allows users to check the performance of the hardware during data taking, providing distributions and history plots of all the parameters. The functionalities of the RPC WBM monitoring tools are presented along with studies of the detector performance as a function of growing luminosity and environmental conditions that are tracked over time.

  12. Web-based monitoring tools for Resistive Plate Chambers in the CMS experiment at CERN

    International Nuclear Information System (INIS)

    Kim, M.S.; Ban, Y.; Cai, J.; Li, Q.; Liu, S.; Qian, S.; Wang, D.; Xu, Z.; Zhang, F.; Choi, Y.; Kim, D.; Goh, J.; Choi, S.; Hong, B.; Kang, J.W.; Kang, M.; Kwon, J.H.; Lee, K.S.; Lee, S.K.; Park, S.K.

    2014-01-01

    The Resistive Plate Chambers (RPC) are used in the CMS experiment at the trigger level and also in the standard offline muon reconstruction. In order to guarantee the quality of the data collected and to monitor online the detector performance, a set of tools has been developed in CMS which is heavily used in the RPC system. The Web-based monitoring (WBM) is a set of java servlets that allows users to check the performance of the hardware during data taking, providing distributions and history plots of all the parameters. The functionalities of the RPC WBM monitoring tools are presented along with studies of the detector performance as a function of growing luminosity and environmental conditions that are tracked over time

  13. Diagnostic tool for structural health monitoring: effect of material nonlinearity and vibro-impact process

    Science.gov (United States)

    Hiwarkar, V. R.; Babitsky, V. I.; Silberschmidt, V. V.

    2013-07-01

    Numerous techniques are available for monitoring structural health. Most of these techniques are expensive and time-consuming. In this paper, vibration-based techniques are explored together with their use as diagnostic tools for structural health monitoring. Finite-element simulations are used to study the effect of material nonlinearity on dynamics of a cracked bar. Additionally, several experiments are performed to study the effect of vibro-impact behavior of crack on its dynamics. It was observed that a change in the natural frequency of the cracked bar due to crack-tip plasticity and vibro-impact behavior linked to interaction of crack faces, obtained from experiments, led to generation of higher harmonics; this can be used as a diagnostic tool for structural health monitoring.

  14. Diagnostic tool for structural health monitoring: effect of material nonlinearity and vibro-impact process

    International Nuclear Information System (INIS)

    Hiwarkar, V R; Babitsky, V I; Silberschmidt, V V

    2013-01-01

    Numerous techniques are available for monitoring structural health. Most of these techniques are expensive and time-consuming. In this paper, vibration-based techniques are explored together with their use as diagnostic tools for structural health monitoring. Finite-element simulations are used to study the effect of material nonlinearity on dynamics of a cracked bar. Additionally, several experiments are performed to study the effect of vibro-impact behavior of crack on its dynamics. It was observed that a change in the natural frequency of the cracked bar due to crack-tip plasticity and vibro-impact behavior linked to interaction of crack faces, obtained from experiments, led to generation of higher harmonics; this can be used as a diagnostic tool for structural health monitoring

  15. Can monitoring of intrathoracic impedance reduce morbidity and mortality in patients with chronic heart failure? Rationale and design of the Diagnostic Outcome Trial in Heart Failure (DOT-HF)

    NARCIS (Netherlands)

    Braunschweig, Frieder; Ford, Ian; Conraads, Viviane; Cowie, Martin R.; Jondeau, Guillaume; Kautzner, Josef; Lunati, Maurizio; Aguilera, Roberto Munoz; Yu, Cheuk Man; Marijianowskii, Monique; Borggrefe, Martin; van Veldhuisen, Dirk J.

    Background: Chronic heart failure is associated with frequent hospitalisations which are often due to volume-overload decompensation. Monitoring of intrathoracic impedance, measured from an implanted device, can detect increases in pulmonary fluid retention early and facilitate timely treatment

  16. New software tool for dynamic radiological characterisation and monitoring in nuclear sites

    International Nuclear Information System (INIS)

    Szoeke, Istvan; Louka, Michael N.; Mark, Niels K.; Bryntesen, Tom R.; Bratteli, Joachim; Edvardsen, Svein T.; Gustavsen, Morten A.; Toppe, Aleksander L.; Johnsen, Terje; Rindahl, Grete

    2012-01-01

    The Halden Reactor Project (HRP) is a jointly sponsored international cooperation, under the aegis of the Organisation for Economic Co-operation and Development - Nuclear Energy Agency. Extensive and valuable guidance and tools, connected to safe and reliable operation of nuclear facilities, has been elaborated throughout the years within the frame of this programme. The HRP has particularly high level results in virtual-reality based tools for real-time areal and personal monitoring. The techniques, developed earlier, are now being supplemented to enhance the planning and monitoring capabilities, and support general radiological characterisation connected to nuclear sites and facilities. Due to the complexity and abundance of the input information required, software tools, dedicated to the radiological characterization of contaminated materials, buildings, land and groundwater, are applied to review, evaluate and visualize the data. Characterisation of the radiation situation in a realistic environment can be very complex, and efficient visualisation of the data to the user is not straight forward. The monitoring and planning tools elaborated in the frame of the HRP feature very sophisticated three-dimensional (3D) high definition visualisation and user interfaces to promote easy interpretation of the input data. The visualisation tools permit dynamic visualisation of radiation fields in virtual or augmented reality by various techniques and real-time personal monitoring of humanoid models. In addition new techniques are being elaborated to visualise the 3D distribution of activities in structures and materials. The dosimetric algorithms, feeding information to the visualisation and user interface of these planning tools, include deterministic radiation transport techniques suitable for fast photon dose estimates, in case physical and radio- and spectrometric characteristics of the gamma sources are known. The basic deterministic model, implemented in earlier

  17. Modeling and monitoring of pipelines and networks advanced tools for automatic monitoring and supervision of pipelines

    CERN Document Server

    Torres, Lizeth

    2017-01-01

    This book focuses on the analysis and design of advanced techniques for on-line automatic computational monitoring of pipelines and pipe networks. It discusses how to improve the systems’ security considering mathematical models of the flow, historical flow rate and pressure data, with the main goal of reducing the number of sensors installed along a pipeline. The techniques presented in the book have been implemented in digital systems to enhance the abilities of the pipeline network’s operators in recognizing anomalies. A real leak scenario in a Mexican water pipeline is used to illustrate the benefits of these techniques in locating the position of a leak. Intended for an interdisciplinary audience, the book addresses researchers and professionals in the areas of mechanical, civil and control engineering. It covers topics on fluid mechanics, instrumentation, automatic control, signal processing, computing, construction and diagnostic technologies.

  18. ''PSAD'' on-line monitoring and aid to diagnosis workstation: a monitoring tool for EDF power plants

    International Nuclear Information System (INIS)

    Morel, J.; Mazalerat, J.M.; Monnier, B.; Cordier, R.

    1993-01-01

    Like other electricity utilities, Electricite de France seeks to enhance the safety and availability of its nuclear power plants. To this end, for over ten years EDF has been installing on each plant unit two monitoring systems of its own design, one to monitor the primary cooling system, and the other, the turbogenerator set. Since the beginning of this project, widespread progress has been made in techniques of signal acquisition and processing, and in diagnosis using artificial intelligence methods. EDF has decided to call on these advanced techniques in developing its new-generation monitoring equipment, and to integrate them in its development of a workstation for on-line monitoring and diagnosis-support (PSAD: Poste de Surveillance et d'Aide au Diagnostic). PSAD will be a tool for on-line monitoring of the main components in nuclear power plants (initially the main coolant pumps and turbogenerator sets, and soon thereafter, monitoring of internal structures, detection of loose parts in the primary cooling system, etc.). PSAD will provide plant personnel with indispensable support in their diagnosis of the condition of plant equipment. It will integrate user-friendly, high-performance systems that also free the operator from many day-to-day tasks. PSAD will have a flexible architecture, for optimum distribution of the computing power where it is most needed, thereby improving the quality of the data. This paper presents the project objectives and describes work currently under way to implement EDF's diagnosis-support strategy for the years to come. (authors). 5 figs., 6 refs

  19. MURMoT. Design and Application of Microbial Uranium Reduction Monitoring Tools

    Energy Technology Data Exchange (ETDEWEB)

    Loeffler, Frank E. [Univ. of Tennessee, Knoxville, TN (United States)

    2014-12-31

    Uranium (U) contamination in the subsurface is a major remediation challenge at many DOE sites. Traditional site remedies present enormous costs to DOE; hence, enhanced bioremediation technologies (i.e., biostimulation and bioaugmentation) combined with monitoring efforts are being considered as cost-effective corrective actions to address subsurface contamination. This research effort improved understanding of the microbial U reduction process and developed new tools for monitoring microbial activities. Application of these tools will promote science-based site management decisions that achieve contaminant detoxification, plume control, and long-term stewardship in the most efficient manner. The overarching hypothesis was that the design, validation and application of a suite of new molecular and biogeochemical tools advance process understanding, and improve environmental monitoring regimes to assess and predict in situ U immobilization. Accomplishments: This project (i) advanced nucleic acid-based approaches to elucidate the presence, abundance, dynamics, spatial distribution, and activity of metal- and radionuclide-detoxifying bacteria; (ii) developed proteomics workflows for detection of metal reduction biomarker proteins in laboratory cultures and contaminated site groundwater; (iii) developed and demonstrated the utility of U isotopic fractionation using high precision mass spectrometry to quantify U(VI) reduction for a range of reduction mechanisms and environmental conditions; and (iv) validated the new tools using field samples from U-contaminated IFRC sites, and demonstrated their prognostic and diagnostic capabilities in guiding decision making for environmental remediation and long-term site stewardship.

  20. Developing a tool to preserve eye contact with patients undergoing colonoscopy for pain monitoring

    Directory of Open Access Journals (Sweden)

    Niv Y

    2012-08-01

    Full Text Available Yaron Niv, Yossi TalDepartment of Gastroenterology, Rabin Medical Center, Tel Aviv University, IsraelAbstract: Colonoscopy has become the leading procedure for early detection and prevention of colorectal cancer. Patients’ experience of colonic endoscopic procedures is scarcely reported, even though it is considered a major factor in colorectal cancer screening participation. Pain due to air inflation or stretching the colon with an endoscope is not rare during examination and may be the main obstacle to cooperation and participation in a screening program. We propose a four-stage study for developing a tool dedicated to pain monitoring during colonoscopy, as follows: (1 comparison of patient, nurse, and endoscopist questionnaire responses about patient pain and technical details of the procedure using the PAINAD tool during colonoscopy; (2 observation of the correlation between patients’ facial expressions and other parameters (using the short PAINAD; (3 development of a device for continuous monitoring of the patient’s facial expression during the procedure; (4 assessment of the usability of such a tool and its contribution to the outcomes of colonoscopy procedures. Early intervention by the staff performing the procedure, in reaction to alerts encoded by this tool, may prevent adverse events during the procedure.Keywords: pain scoring, colonoscopy, pain monitoring, facial expression

  1. The development of daily monitoring tool in a service part manufacturing company

    Science.gov (United States)

    Marpaung, Seamus Tadeo; Rosyidi, Cucuk Nur

    2018-02-01

    Production lead time is one of the key measures to assess whether a production system is running well or not. A short lead time will lead to higher customer satisfaction and will be a solid proof that a system is well-organized. To shorten the production lead time, a good production planning and control are required. There are many obstacles which can occur at any time, for instance shortage of material and worker, or poor production scheduling. Service Parts Planning Department works with many parties from the beginning of service parts production until it is delivered to the customer. This research was conducted to find an appropriate production monitoring tool for Service Parts Planning Department, which is a control method that make problems appears to the surface and can be overcome quickly so that the production process can run normally. The tool development started with a field study to find out the production flow from start to finish, a literature review and a interview with some employees who will later use the production control tool, and the creation of a daily control that went through several modifications until finally meet the needs of the department. In this research, a production monitoring tool which is developed can be used to monitor the entire order status, the production lead time, and also serves as the records and reports for presentation.

  2. The influence of deformation-induced microvoids on mechanical failure of AISI A8-Mod martensitic tool steel

    Science.gov (United States)

    Ghasemi-Nanesa, Hadi; Jahazi, Mohammad; Heidari, Majid; Levasseur, Tom

    2017-10-01

    Tool steels are considered as hard to deform materials since they have a mixture of soft ferritic matrix with hard carbides as secondary particles. In this study, 5 mm thick plates of AISI A8-Modified tool steel were subjected to cold rolling prior to the quench-temper cycle with the view to investigate the work hardening behavior of this steel during rolling and to reduce the brittleness of the product after the quench-temper cycle. 5mm thick samples were rolled 10, 20, 30, 40, and 50 (%) under similar conditions and then cut parallel to the rolling direction. Microstructure evolution, deformation-induced microvoids, and hardness evolution as a function of prior deformation were investigated. Electron microscopy was used to investigate the root causes for the formation of microvoids and potential alligatoring failure. The influence of microvoids on mechanical properties after the quench-temper cycle was evaluated through bending tests. Results showed no failure for 50% cold rolled sample in comparison with fracture for non-deformed sample indicating that prior deformation could be a novel route for improving the in service properties of these alloys. Hardness of 50% cold rolled after thermal hardening was lower than that for non-deformed sample. The analysis of prior austenite grain size, volume fraction of retained austenite, and volume fraction of carbides for both testing conditions showed that hardness reduction can be related to the presence of microvoids formed in the microstructure during rolling.

  3. Monitoring failure rates of commercial implant brands; substantial equivalence in question?

    Science.gov (United States)

    Hujoel, Philippe; Becker, William; Becker, Burton

    2013-07-01

    The aim of this study was to report on the failure rates of two distinct dental implant systems in a clinical practice setting. Date of implant placement and loss were entered prospectively in a data registry system. Failure rates of two commercially pure titanium implants, one with a porous oxydized surface (POS) and the other with a chemically altered surface (CAS), were assessed using a quality control chart and survival analyses. A total of 860 POS and 759 CAS implants were placed. A warning of an increased failure rate of the CAS implant was identified by means of the quality control chart. Survival analyses indicated that the CAS implant failure rate was twice that of the POS implant (Hazard Ratio: 2.08; 95% CI: 1.33-3.28, P-value POS implant was associated with a non-significant 64% drop in the implant failure rate within less than a year (HR: 0.36; 95% CI: 0.12-1.14; P-value POS implant and an 8% failure with the CAS implant appears inconsistent with the assumption of substantial equivalence. © 2012 John Wiley & Sons A/S.

  4. Predictive analytics tools to adjust and monitor performance metrics for the ATLAS Production System

    CERN Document Server

    Barreiro Megino, Fernando Harald; The ATLAS collaboration

    2017-01-01

    Having information such as an estimation of the processing time or possibility of system outage (abnormal behaviour) helps to assist to monitor system performance and to predict its next state. The current cyber-infrastructure presents computing conditions in which contention for resources among high-priority data analysis happens routinely, that might lead to significant workload and data handling interruptions. The lack of the possibility to monitor and to predict the behaviour of the analysis process (its duration) and system’s state itself caused to focus on design of the built-in situational awareness analytic tools.

  5. Tool wear monitoring by machine learning techniques and singular spectrum analysis

    Science.gov (United States)

    Kilundu, Bovic; Dehombreux, Pierre; Chiementin, Xavier

    2011-01-01

    This paper explores the use of data mining techniques for tool condition monitoring in metal cutting. Pseudo-local singular spectrum analysis (SSA) is performed on vibration signals measured on the toolholder. This is coupled to a band-pass filter to allow definition and extraction of features which are sensitive to tool wear. These features are defined, in some frequency bands, from sums of Fourier coefficients of reconstructed and residual signals obtained by SSA. This study highlights two important aspects: strong relevance of information in high frequency vibration components and benefits of the combination of SSA and band-pass filtering to get rid of useless components (noise).

  6. PROMO: a computerized tool to support process monitoring activities -application in CANDU simulators

    International Nuclear Information System (INIS)

    Singh, D.T.; Singh, P.P.

    1995-01-01

    PROMO, a prototype computerized PROcess MOnitoring tool, has been designed for the resolution of perceived complexity under conditions of time constraints and criticality. It is suggested that this makes it uniquely suitable for applications such as nuclear power plant operator training and support. This paper describes the tool, the theory underlying its design, and results from preliminary laboratory experiments. While field tests are necessary prior to the drawing of conclusions, the results from the laboratory trials are promising. Efforts are currently underway to extend the research setting to power plant operator training centers. (author). 57 refs., 1 fig

  7. [Hospital statistics as tool in epidemiologic studies: heart failure in Trieste].

    Science.gov (United States)

    Di Lenarda, Andrea; Goliani, Paolo; Grella, Maddalena; Sabbadini, Gastone; Driussi, Mauro; Sinagra, Gianfranco

    2002-01-01

    Since 1995, the reimbursement of hospital healthcare expenditure in Italy has been based upon the so-called Diagnosis Related Groups (DRGs). The DRG 127 includes all the cases in which the main clinical diagnosis is "heart failure or shock" and, therefore, it may be used to obtain epidemiological data concerning this syndrome. The analysis appears to be of relevance, since in the district of Trieste the phenomenon of progressive aging of the general population has already reached a very advanced phase. In this study, we evaluated, using the database of the Sistema Informativo Sanitario Regionale, the epidemiological data and clinical outcome of patients hospitalized for DRG 127 in the district of Trieste from 1997 to 2000 (5514 hospital admissions and 69,236 days of hospital stay). The DRG 127 accounted for 2.6% of the total hospital admissions and 4% of the total days of hospital stay; moreover, it was found to be the first cause of hospitalization for medical DRGs (18.8%) as well as the first cause of hospitalization and of the days of hospital stay for cardiovascular DRGs (27.5 and 40.5%, respectively). Seventy-two percent of patients admitted for DRG 127 were > 75 years. In 1997, a mean of 4/1000 inhabitants of the district of Trieste were hospitalized for DRG 127 (4.6 hospital admissions and 63 days of hospital stay/1000 inhabitants). Over the 4-year period, the number of hospital admissions for DRG 127 increased by 20.4%, the days of hospital stay by 11.1%, and the related healthcare costs rose by 36.7%. Most of the patients (89%) were admitted in Internal Medicine or Geriatric wards. By using suitable corrective factors, the prevalence rate of heart failure in 1997 was estimated at 6.4@1000 ( or = 85 years 47.4@1000). On the basis of the first hospital admission, the incidence was estimated at 2.4@1000 ( or = 85 years 20.4@1000). The in-hospital 1-, 2- and 3-year survival rates from the time of the first hospital admission for heart failure were

  8. Development of a practice tool for community-based nurses: the Heart Failure Palliative Approach to Care (HeFPAC).

    Science.gov (United States)

    Strachan, Patricia H; Joy, Cathy; Costigan, Jeannine; Carter, Nancy

    2014-04-01

    Patients living with advanced heart failure (HF) require a palliative approach to reduce suffering. Nurses have described significant knowledge gaps about the disease-specific palliative care (PC) needs of these patients. An intervention is required to facilitate appropriate end-of-life care for HF patients. The purpose of this study was to develop a user-friendly, evidence-informed HF-specific practice tool for community-based nurses to facilitate care and communication regarding a palliative approach to HF care. Guided by the Knowledge to Action framework, we identified key HF-specific issues related to advanced HF care provision within the context of a palliative approach to care. Informed by current evidence and subsequent iterative consultation with community-based and specialist PC and HF nurses, a pocket guide tool for community-based nurses was created. We developed the Heart Failure Palliative Approach to Care (HeFPAC) pocket guide to promote communication and a palliative approach to care for HF patients. The HeFPAC has potential to improve the quality of care and experiences for patients with advanced HF. It will be piloted in community-based practice and in a continuing education program for nurses. The HeFPAC pocket guide offers PC nurses a concise, evidence-informed and practical point-of care tool to communicate with other clinicians and patients about key HF issues that are associated with improving disease-specific HF palliative care and the quality of life of patients and their families. Pilot testing will offer insight as to its utility and potential for modification for national and international use.

  9. EEG-based "serious" games and monitoring tools for pain management.

    Science.gov (United States)

    Sourina, Olga; Wang, Qiang; Nguyen, Minh Khoa

    2011-01-01

    EEG-based "serious games" for medical applications attracted recently more attention from the research community and industry as wireless EEG reading devices became easily available on the market. EEG-based technology has been applied in anesthesiology, psychology, etc. In this paper, we proposed and developed EEG-based "serious" games and doctor's monitoring tools that could be used for pain management. As EEG signal is considered to have a fractal nature, we proposed and develop a novel spatio-temporal fractal based algorithm for brain state quantification. The algorithm is implemented with blobby visualization tools for patient monitoring and in EEG-based "serious" games. Such games could be used by patient even at home convenience for pain management as an alternative to traditional drug treatment.

  10. The safety monitor and RCM workstation as complementary tools in risk based maintenance optimization

    International Nuclear Information System (INIS)

    Rawson, P.D.

    2000-01-01

    Reliability Centred Maintenance (RCM) represents a proven technique for rendering maintenance activities safer, more effective, and less expensive, in terms of systems unavailability and resource management. However, it is believed that RCM can be enhanced by the additional consideration of operational plant risk. This paper discusses how two computer-based tools, i.e., the RCM Workstation and the Safety Monitor, can complement each other in helping to create a living preventive maintenance strategy. (author)

  11. CD4 count-based failure criteria combined with viral load monitoring may trigger worse switch decisions than viral load monitoring alone.

    Science.gov (United States)

    Hoffmann, Christopher J; Maritz, Jean; van Zyl, Gert U

    2016-02-01

    CD4 count decline often triggers antiretroviral regimen switches in resource-limited settings, even when viral load testing is available. We therefore compared CD4 failure and CD4 trends in patients with viraemia with or without antiretroviral resistance. Retrospective cohort study investigating the association of HIV drug resistance with CD4 failure or CD4 trends in patients on first-line antiretroviral regimens during viraemia. Patients with viraemia (HIV RNA >1000 copies/ml) from two HIV treatment programmes in South Africa (n = 350) were included. We investigated the association of M184V and NNRTI resistance with WHO immunological failure criteria and CD4 count trends, using chi-square tests and linear mixed models. Fewer patients with the M184V mutation reached immunologic failure criteria than those without: 51 of 151(34%) vs. 90 of 199 (45%) (P = 0.03). Similarly, 79 of 220 (36%) patients, who had major NNRTI resistance, had immunological failure, whereas 62 of 130 (48%) without (chi-square P = 0.03) did. The CD4 count decline among patients with the M184V mutation was 2.5 cells/mm(3) /year, whereas in those without M184V it was 14 cells/mm(3) /year (P = 0.1), but the difference in CD4 count decline with and without NNRTI resistance was marginal. Our data suggest that CD4 count monitoring may lead to inappropriate delayed therapy switches for patients with HIV drug resistance. Conversely, patients with viraemia but no drug resistance are more likely to have a CD4 count decline and thus may be more likely to be switched to a second-line regimen. © 2015 John Wiley & Sons Ltd.

  12. Cointegration as a data normalization tool for structural health monitoring applications

    Science.gov (United States)

    Harvey, Dustin Y.; Todd, Michael D.

    2012-04-01

    The structural health monitoring literature has shown an abundance of features sensitive to various types of damage in laboratory tests. However, robust feature extraction in the presence of varying operational and environmental conditions has proven to be one of the largest obstacles in the development of practical structural health monitoring systems. Cointegration, a technique adapted from the field of econometrics, has recently been introduced to the SHM field as one solution to the data normalization problem. Response measurements and feature histories often show long-run nonstationarity due to fluctuating temperature, load conditions, or other factors that leads to the occurrence of false positives. Cointegration theory allows nonstationary trends common to two or more time series to be modeled and subsequently removed. Thus, the residual retains sensitivity to damage with dependence on operational and environmental variability removed. This study further explores the use of cointegration as a data normalization tool for structural health monitoring applications.

  13. A failure-type specific risk prediction tool for selection of head-and-neck cancer patients for experimental treatments

    DEFF Research Database (Denmark)

    Håkansson, Katrin; Rasmussen, Jacob H.; Rasmussen, Gregers B.

    2017-01-01

    OBJECTIVES: The objective of this work was to develop a tool for decision support, providing simultaneous predictions of the risk of loco-regional failure (LRF) and distant metastasis (DM) after definitive treatment for head-and-neck squamous cell carcinoma (HNSCC). MATERIALS AND METHODS......: Retrospective data for 560HNSCC patients were used to generate a multi-endpoint model, combining three cause-specific Cox models (LRF, DM and death with no evidence of disease (death NED)). The model was used to generate risk profiles of patients eligible for/included in a de-intensification study (RTOG 1016.......8%, p20% risk of tumor relapse. Conversely, 9 of the 15 dose escalation trial participants had LRF risks

  14. Development of a novel heart failure risk tool: the barcelona bio-heart failure risk calculator (BCN bio-HF calculator).

    Science.gov (United States)

    Lupón, Josep; de Antonio, Marta; Vila, Joan; Peñafiel, Judith; Galán, Amparo; Zamora, Elisabet; Urrutia, Agustín; Bayes-Genis, Antoni

    2014-01-01

    A combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF). A novel calculator (BCN Bio-HF calculator) incorporating N-terminal pro B-type natriuretic peptide (NT-proBNP, a marker of myocardial stretch), high-sensitivity cardiac troponin T (hs-cTnT, a marker of myocyte injury), and high-sensitivity soluble ST2 (ST2), (reflective of myocardial fibrosis and remodeling) was developed. Model performance was evaluated using discrimination, calibration, and reclassification tools for 1-, 2-, and 3-year mortality. Ten-fold cross-validation with 1000 bootstrapping was used. The BCN Bio-HF calculator was derived from 864 consecutive outpatients (72% men) with mean age 68.2 ± 12 years (73%/27% New York Heart Association (NYHA) class I-II/III-IV, LVEF 36%, ischemic etiology 52.2%) and followed for a median of 3.4 years (305 deaths). After an initial evaluation of 23 variables, eight independent models were developed. The variables included in these models were age, sex, NYHA functional class, left ventricular ejection fraction, serum sodium, estimated glomerular filtration rate, hemoglobin, loop diuretic dose, β-blocker, Angiotensin converting enzyme inhibitor/Angiotensin-2 receptor blocker and statin treatments, and hs-cTnT, ST2, and NT-proBNP levels. The calculator may run with the availability of none, one, two, or the three biomarkers. The calculated risk of death was significantly changed by additive biomarker data. The average C-statistic in cross-validation analysis was 0.79. A new HF risk-calculator that incorporates available biomarkers reflecting different pathophysiological pathways better allowed individual prediction of death at 1, 2, and 3 years.

  15. Development of a novel heart failure risk tool: the barcelona bio-heart failure risk calculator (BCN bio-HF calculator.

    Directory of Open Access Journals (Sweden)

    Josep Lupón

    Full Text Available BACKGROUND: A combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF. A novel calculator (BCN Bio-HF calculator incorporating N-terminal pro B-type natriuretic peptide (NT-proBNP, a marker of myocardial stretch, high-sensitivity cardiac troponin T (hs-cTnT, a marker of myocyte injury, and high-sensitivity soluble ST2 (ST2, (reflective of myocardial fibrosis and remodeling was developed. METHODS: Model performance was evaluated using discrimination, calibration, and reclassification tools for 1-, 2-, and 3-year mortality. Ten-fold cross-validation with 1000 bootstrapping was used. RESULTS: The BCN Bio-HF calculator was derived from 864 consecutive outpatients (72% men with mean age 68.2 ± 12 years (73%/27% New York Heart Association (NYHA class I-II/III-IV, LVEF 36%, ischemic etiology 52.2% and followed for a median of 3.4 years (305 deaths. After an initial evaluation of 23 variables, eight independent models were developed. The variables included in these models were age, sex, NYHA functional class, left ventricular ejection fraction, serum sodium, estimated glomerular filtration rate, hemoglobin, loop diuretic dose, β-blocker, Angiotensin converting enzyme inhibitor/Angiotensin-2 receptor blocker and statin treatments, and hs-cTnT, ST2, and NT-proBNP levels. The calculator may run with the availability of none, one, two, or the three biomarkers. The calculated risk of death was significantly changed by additive biomarker data. The average C-statistic in cross-validation analysis was 0.79. CONCLUSIONS: A new HF risk-calculator that incorporates available biomarkers reflecting different pathophysiological pathways better allowed individual prediction of death at 1, 2, and 3 years.

  16. Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure.

    Science.gov (United States)

    Reed, Shelby D; Neilson, Matthew P; Gardner, Matthew; Li, Yanhong; Briggs, Andrew H; Polsky, Daniel E; Graham, Felicia L; Bowers, Margaret T; Paul, Sara C; Granger, Bradi B; Schulman, Kevin A; Whellan, David J; Riegel, Barbara; Levy, Wayne C

    2015-11-01

    Heart failure disease management programs can influence medical resource use and quality-adjusted survival. Because projecting long-term costs and survival is challenging, a consistent and valid approach to extrapolating short-term outcomes would be valuable. We developed the Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model, a Web-based simulation tool designed to integrate data on demographic, clinical, and laboratory characteristics; use of evidence-based medications; and costs to generate predicted outcomes. Survival projections are based on a modified Seattle Heart Failure Model. Projections of resource use and quality of life are modeled using relationships with time-varying Seattle Heart Failure Model scores. The model can be used to evaluate parallel-group and single-cohort study designs and hypothetical programs. Simulations consist of 10,000 pairs of virtual cohorts used to generate estimates of resource use, costs, survival, and incremental cost-effectiveness ratios from user inputs. The model demonstrated acceptable internal and external validity in replicating resource use, costs, and survival estimates from 3 clinical trials. Simulations to evaluate the cost-effectiveness of heart failure disease management programs across 3 scenarios demonstrate how the model can be used to design a program in which short-term improvements in functioning and use of evidence-based treatments are sufficient to demonstrate good long-term value to the health care system. The Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model provides researchers and providers with a tool for conducting long-term cost-effectiveness analyses of disease management programs in heart failure. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Evaluation of Heat Flux Measurement as a New Process Analytical Technology Monitoring Tool in Freeze Drying.

    Science.gov (United States)

    Vollrath, Ilona; Pauli, Victoria; Friess, Wolfgang; Freitag, Angelika; Hawe, Andrea; Winter, Gerhard

    2017-05-01

    This study investigates the suitability of heat flux measurement as a new technique for monitoring product temperature and critical end points during freeze drying. The heat flux sensor is tightly mounted on the shelf and measures non-invasively (no contact with the product) the heat transferred from shelf to vial. Heat flux data were compared to comparative pressure measurement, thermocouple readings, and Karl Fischer titration as current state of the art monitoring techniques. The whole freeze drying process including freezing (both by ramp freezing and controlled nucleation) and primary and secondary drying was considered. We found that direct measurement of the transferred heat enables more insights into thermodynamics of the freezing process. Furthermore, a vial heat transfer coefficient can be calculated from heat flux data, which ultimately provides a non-invasive method to monitor product temperature throughout primary drying. The end point of primary drying determined by heat flux measurements was in accordance with the one defined by thermocouples. During secondary drying, heat flux measurements could not indicate the progress of drying as monitoring the residual moisture content. In conclusion, heat flux measurements are a promising new non-invasive tool for lyophilization process monitoring and development using energy transfer as a control parameter. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  18. Collaboration pathway(s) using new tools for optimizing `operational' climate monitoring from space

    Science.gov (United States)

    Helmuth, Douglas B.; Selva, Daniel; Dwyer, Morgan M.

    2015-09-01

    Consistently collecting the earth's climate signatures remains a priority for world governments and international scientific organizations. Architecting a long term solution requires transforming scientific missions into an optimized robust `operational' constellation that addresses the collective needs of policy makers, scientific communities and global academic users for trusted data. The application of new tools offers pathways for global architecture collaboration. Recent rule-based expert system (RBES) optimization modeling of the intended NPOESS architecture becomes a surrogate for global operational climate monitoring architecture(s). These rulebased systems tools provide valuable insight for global climate architectures, by comparison/evaluation of alternatives and the sheer range of trade space explored. Optimization of climate monitoring architecture(s) for a partial list of ECV (essential climate variables) is explored and described in detail with dialogue on appropriate rule-based valuations. These optimization tool(s) suggest global collaboration advantages and elicit responses from the audience and climate science community. This paper will focus on recent research exploring joint requirement implications of the high profile NPOESS architecture and extends the research and tools to optimization for a climate centric case study. This reflects work from SPIE RS Conferences 2013 and 2014, abridged for simplification30, 32. First, the heavily securitized NPOESS architecture; inspired the recent research question - was Complexity (as a cost/risk factor) overlooked when considering the benefits of aggregating different missions into a single platform. Now years later a complete reversal; should agencies considering Disaggregation as the answer. We'll discuss what some academic research suggests. Second, using the GCOS requirements of earth climate observations via ECV (essential climate variables) many collected from space-based sensors; and accepting their

  19. Animal-based welfare monitoring: using keeper ratings as an assessment tool.

    Science.gov (United States)

    Whitham, Jessica C; Wielebnowski, Nadja

    2009-11-01

    Zoological institutions are in urgent need of identifying and implementing welfare assessment tools that allow for ongoing, quantitative monitoring of individual animal well-being. Although the American Zoological Association's (AZA) Animal Welfare Committee (AWC) promotes the use of such tools in internal review processes, current approaches to institutional welfare assessment are resource-based and outline the resources, environmental parameters and "best practices" recommended for promoting good welfare in a species in general. We highlight the value of incorporating animal-based monitoring tools that capture the individual animal's perspective and subjective experiences, including positive events and feelings, by validating zookeepers' qualitative assessments. We present evidence that, across a variety of species, caretakers' assessments of traits related to the well-being of individual animals can be both reliable and valid. Furthermore, we demonstrate that among researchers investigating the welfare of farm, laboratory, companion and even zoo animals, support already exists for developing and validating instruments that objectively evaluate the qualitative assessments of caretakers. Finally, we outline a process currently being evaluated at Brookfield Zoo for developing, validating and testing a cost-effective, user-friendly monitoring tool that will help to quantify keepers' qualitative assessments of individual well-being and can be integrated into daily operations. This tool (i.e. species-specific Welfare Score Sheets designed through consultation with animal experts) will result in weekly scores of individual well-being that are expected to provide a first indicator of welfare issues in the collection. Specifically, scores can be reviewed during regular workgroup meetings to identify welfare issues proactively, to assess whether particular conditions, practices or events impact individual well-being, and finally, to evaluate the effectiveness of efforts

  20. HappyFace as a generic monitoring tool for HEP experiments

    Science.gov (United States)

    Kawamura, Gen; Magradze, Erekle; Musheghyan, Haykuhi; Quadt, Arnulf; Rzehorz, Gerhard

    2015-12-01

    The importance of monitoring on HEP grid computing systems is growing due to a significant increase in their complexity. Computer scientists and administrators have been studying and building effective ways to gather information on and clarify a status of each local grid infrastructure. The HappyFace project aims at making the above-mentioned workflow possible. It aggregates, processes and stores the information and the status of different HEP monitoring resources into the common database of HappyFace. The system displays the information and the status through a single interface. However, this model of HappyFace relied on the monitoring resources which are always under development in the HEP experiments. Consequently, HappyFace needed to have direct access methods to the grid application and grid service layers in the different HEP grid systems. To cope with this issue, we use a reliable HEP software repository, the CernVM File System. We propose a new implementation and an architecture of HappyFace, the so-called grid-enabled HappyFace. It allows its basic framework to connect directly to the grid user applications and the grid collective services, without involving the monitoring resources in the HEP grid systems. This approach gives HappyFace several advantages: Portability, to provide an independent and generic monitoring system among the HEP grid systems. Eunctionality, to allow users to perform various diagnostic tools in the individual HEP grid systems and grid sites. Elexibility, to make HappyFace beneficial and open for the various distributed grid computing environments. Different grid-enabled modules, to connect to the Ganga job monitoring system and to check the performance of grid transfers among the grid sites, have been implemented. The new HappyFace system has been successfully integrated and now it displays the information and the status of both the monitoring resources and the direct access to the grid user applications and the grid collective

  1. Monitoring the efficacy of antimalarial medicines in India via sentinel sites: Outcomes and risk factors for treatment failure.

    Science.gov (United States)

    Mishra, Neelima; Srivastava, Bina; Bharti, Ram Suresh; Rana, Roma; Kaitholia, Kamlesh; Anvikar, Anupkumar R; Das, Manoj Kumar; Ghosh, Susanta K; Bhatt, Rajendra M; Tyagi, Prajesh K; Dev, Vas; Phookan, Sobhan; Wattal, Suman Lata; Sonal, Gagan Singh; Dhariwal, Akshay Chand; Valecha, Neena

    2016-01-01

    To combat the problem of antimalarial drug resistance, monitoring the changes in drug efficacy over time through periodic surveillance is essential. Since 2009, systematic and continuous monitoring is being done through nationwide sentinel site system. Potential early warning signs like partner drug resistance markers were also monitored in the clinical samples from the study areas. A total of 1864 patients with acute uncomplicated malaria were enrolled in therapeutic efficacy studies of artesunate plus sulphadoxine-pyrimethamine (AS+SP) for Plasmodium falciparum; those infected with P. vivax were given chloroquine (CQ). Polymerase chain reaction (PCR) was used to distinguish post-treatment reinfection from treatment failures. Isolates of P. falciparum were also analysed for dihydropteroate synthase (dhps) and dihydrofolate reductase (dhfr) gene mutations. Overall, 1687 (91.7%) patients completed the follow-up. In most of the falciparum patients the parasitaemia was cleared within 24 h of treatment, except 12 patients who remained parasite positive after 72 h. Presence of dhfr and dhps quintuple mutation was observed predominantly in treatment failure samples. A daily dose of artesunate of 95% cases in all the sentinel sites except in Northeastern region (NE). Chloroquine remained 100% efficacious in case of P. vivax infections. Till 2012, India's national antimalarial drug resistance monitoring system proved highly efficacious and safe towards first-line antimalarials used in the country, except in Northeastern region where a decline in efficacy of AS+SP has been observed. This led to change in first-line treatment for P. falciparum to artemether-lumefantrine in Northeastern region.

  2. Analysis of trends in fuel rod depressurization and determination of 'gas leak' and 'pellet-water interaction' type failures using radiation monitoring techniques of fuel rod leak tightness

    International Nuclear Information System (INIS)

    Panov, E.A.; Shestakov, Yu.M.; Miglo, V.N.

    1993-01-01

    Analysis of fuel rod failures in the Light Water Reactor operation is presented. Analysis includes the mechanism of formation and development of fuel rod cladding failure until through-wall defects appear (welding defects; inner hydriding defects; pellet-cladding interaction; crud deposit - intensified corrosion) as well as factors that determine defects propagation after fuel rod depressurization (metal condition in the vicinity of defect determined by the mechanism of formation and propagation defect; operational transients; degree of core cooldown after depressurization during preventive maintenance). Possibilities of in-service monitoring of fuel rod through-wall crack propagation using normal tools of cladding back-tightness monitoring are addressed and used in the course of analysis. Characteristics and values are presented for radiation parameters for fuel assemblies during propagation of defects with different degrees of rod depressurization, including ''gas leak'', cladding crack and ''open pellet-water interaction'' with potential particulate fission product release from the damaged rods as well as after formation of recurring defects. Based on experimental data on specific activity of different iodine isotopes in the primary coolant, a mathematical model to analyse defect propagation trends has been developed. The model describes the rate of radionuclide release from depressurized rods and the rate of nuclear fuel fission processes in the vicinity of defects. The model and results of analysis are illustrated by experimental and statistical data on depressurization of WWER (PWR) and RBMK (BWR) reactor fuel rods. Possibility to solve the problem of predicting defect propagation is considered. (author). 5 refs, 9 figs, 3 tabs

  3. Nucleic acids-based tools for ballast water surveillance, monitoring, and research

    Science.gov (United States)

    Darling, John A.; Frederick, Raymond M.

    2018-03-01

    Understanding the risks of biological invasion posed by ballast water-whether in the context of compliance testing, routine monitoring, or basic research-is fundamentally an exercise in biodiversity assessment, and as such should take advantage of the best tools available for tackling that problem. The past several decades have seen growing application of genetic methods for the study of biodiversity, driven in large part by dramatic technological advances in nucleic acids analysis. Monitoring approaches based on such methods have the potential to increase dramatically sampling throughput for biodiversity assessments, and to improve on the sensitivity, specificity, and taxonomic accuracy of traditional approaches. The application of targeted detection tools (largely focused on PCR but increasingly incorporating novel probe-based methodologies) has led to a paradigm shift in rare species monitoring, and such tools have already been applied for early detection in the context of ballast water surveillance. Rapid improvements in community profiling approaches based on high throughput sequencing (HTS) could similarly impact broader efforts to catalogue biodiversity present in ballast tanks, and could provide novel opportunities to better understand the risks of biotic exchange posed by ballast water transport-and the effectiveness of attempts to mitigate those risks. These various approaches still face considerable challenges to effective implementation, depending on particular management or research needs. Compliance testing, for instance, remains dependent on accurate quantification of viable target organisms; while tools based on RNA detection show promise in this context, the demands of such testing require considerable additional investment in methods development. In general surveillance and research contexts, both targeted and community-based approaches are still limited by various factors: quantification remains a challenge (especially for taxa in larger size

  4. Emerging tools for continuous nutrient monitoring networks: Sensors advancing science and water resources protection

    Science.gov (United States)

    Pellerin, Brian; Stauffer, Beth A; Young, Dwane A; Sullivan, Daniel J.; Bricker, Suzanne B.; Walbridge, Mark R; Clyde, Gerard A; Shaw, Denice M

    2016-01-01

    Sensors and enabling technologies are becoming increasingly important tools for water quality monitoring and associated water resource management decisions. In particular, nutrient sensors are of interest because of the well-known adverse effects of nutrient enrichment on coastal hypoxia, harmful algal blooms, and impacts to human health. Accurate and timely information on nutrient concentrations and loads is integral to strategies designed to minimize risk to humans and manage the underlying drivers of water quality impairment. Using nitrate sensors as an example, we highlight the types of applications in freshwater and coastal environments that are likely to benefit from continuous, real-time nutrient data. The concurrent emergence of new tools to integrate, manage and share large data sets is critical to the successful use of nutrient sensors and has made it possible for the field of continuous nutrient monitoring to rapidly move forward. We highlight several near-term opportunities for Federal agencies, as well as the broader scientific and management community, that will help accelerate sensor development, build and leverage sites within a national network, and develop open data standards and data management protocols that are key to realizing the benefits of a large-scale, integrated monitoring network. Investing in these opportunities will provide new information to guide management and policies designed to protect and restore our nation’s water resources.

  5. Evaluation of Passive Samplers as a Monitoring Tool for Early Warning of Dinophysis Toxins in Shellfish

    Science.gov (United States)

    Pizarro, Gemita; Moroño, Ángeles; Paz, Beatriz; Franco, José M.; Pazos, Yolanda; Reguera, Beatriz

    2013-01-01

    From June 2006 to January 2007 passive samplers (solid phase adsorbing toxin tracking, SPATT) were tested as a monitoring tool with weekly monitoring of phytoplankton and toxin content (liquid chromatography–mass spectrometry, LC-MS) in picked cells of Dinophysis and plankton concentrates. Successive blooms of Dinophysis acuminata, D. acuta and D. caudata in 2006 caused a long mussel harvesting closure (4.5 months) in the Galician Rías (NW Spain) and a record (up to 9246 ng·g resin-week−1) accumulation of toxins in SPATT discs. Best fit of a toxin accumulation model was between toxin accumulation in SPATT and the product of cell densities by a constant value, for each species of Dinophysis, of toxin content (average) in picked cells. Detection of Dinophysis populations provided earlier warning of oncoming diarrhetic shellfish poisoning (DSP) outbreaks than the SPATT, which at times overestimated the expected toxin levels in shellfish because: (i) SPATT accumulated toxins did not include biotransformation and depuration loss terms and (ii) accumulation of toxins not available to mussels continued for weeks after Dinophysis cells were undetectable and mussels were toxin-free. SPATT may be a valuable environmental monitoring and research tool for toxin dynamics, in particular in areas with no aquaculture, but does not provide a practical gain for early warning of DSP outbreaks. PMID:24152559

  6. A real time dose monitoring and dose reconstruction tool for patient specific VMAT QA and delivery

    International Nuclear Information System (INIS)

    Tyagi, Neelam; Yang Kai; Gersten, David; Yan Di

    2012-01-01

    Purpose: To develop a real time dose monitoring and dose reconstruction tool to identify and quantify sources of errors during patient specific volumetric modulated arc therapy (VMAT) delivery and quality assurance. Methods: The authors develop a VMAT delivery monitor tool called linac data monitor that connects to the linac in clinical mode and records, displays, and compares real time machine parameters with the planned parameters. A new measure, called integral error, keeps a running total of leaf overshoot and undershoot errors in each leaf pair, multiplied by leaf width, and the amount of time during which the error exists in monitor unit delivery. Another tool reconstructs Pinnacle 3 ™ format delivered plan based on the saved machine logfile and recalculates actual delivered dose in patient anatomy. Delivery characteristics of various standard fractionation and stereotactic body radiation therapy (SBRT) VMAT plans delivered on Elekta Axesse and Synergy linacs were quantified. Results: The MLC and gantry errors for all the treatment sites were 0.00 ± 0.59 mm and 0.05 ± 0.31°, indicating a good MLC gain calibration. Standard fractionation plans had a larger gantry error than SBRT plans due to frequent dose rate changes. On average, the MLC errors were negligible but larger errors of up to 6 mm and 2.5° were seen when dose rate varied frequently. Large gantry errors occurred during the acceleration and deceleration process, and correlated well with MLC errors (r= 0.858, p= 0.0004). PTV mean, minimum, and maximum dose discrepancies were 0.87 ± 0.21%, 0.99 ± 0.59%, and 1.18 ± 0.52%, respectively. The organs at risk (OAR) doses were within 2.5%, except some OARs that showed up to 5.6% discrepancy in maximum dose. Real time displayed normalized total positive integral error (normalized to the total monitor units) correlated linearly with MLC (r= 0.9279, p < 0.001) and gantry errors (r= 0.742, p= 0.005). There is a strong correlation between total integral

  7. Development of Dual-Axis MEMS Accelerometers for Machine Tools Vibration Monitoring

    Directory of Open Access Journals (Sweden)

    Chih-Yung Huang

    2016-07-01

    Full Text Available With the development of intelligent machine tools, monitoring the vibration by the accelerometer is an important issue. Accelerometers used for measuring vibration signals during milling processes require the characteristics of high sensitivity, high resolution, and high bandwidth. A commonly used accelerometer is the lead zirconate titanate (PZT type; however, integrating it into intelligent modules is excessively expensive and difficult. Therefore, the micro electro mechanical systems (MEMS accelerometer is an alternative with the advantages of lower price and superior integration. In the present study, we integrated two MEMS accelerometer chips into a low-pass filter and housing to develop a low-cost dual-axis accelerometer with a bandwidth of 5 kHz and a full scale range of ±50 g for measuring machine tool vibration. In addition, a platform for measuring the linearity, cross-axis sensitivity and frequency response of the MEMS accelerometer by using the back-to-back calibration method was also developed. Finally, cutting experiments with steady and chatter cutting were performed to verify the results of comparing the MEMS accelerometer with the PZT accelerometer in the time and frequency domains. The results demonstrated that the dual-axis MEMS accelerometer is suitable for monitoring the vibration of machine tools at low cost.

  8. Moving towards tangible decision-making tools for policy makers: Measuring and monitoring energy access provision

    International Nuclear Information System (INIS)

    Bhanot, Jaya; Jha, Vivek

    2012-01-01

    Access to energy services has been recognised as central to achieving economic growth and sustainable development. However, almost 1.3 billion people in the world still lack access to electricity and 2.7 billion lack access to clean cooking facilities. In this backdrop, the issue of energy access is receiving more interest than ever before and this has brought to the fore, the need for a robust decision support tool for policy makers to measure the progress of energy access provision and also to provide direction for future policy making. The paper studies existing definitions of energy access and identifies the key requirements for an appropriate decision-making tool to measure and monitor energy access provision. In this context the paper assesses the strengths and weaknesses of the metrics currently being used to measure energy access in policy, as well as of contemporary monitoring and evaluation frameworks being used in other sectors. Based on these insights, a dashboard of indicators is proposed as an alternate decision support tool for policy makers to measure energy access. The paper concludes with a discussion on what is needed to operationalise this proposed framework. - Highlights: ► No one indicator or metric can successfully capture progress on energy access. ► A service oriented approach is necessary to measure energy access. ► Socio-economic and political contexts influence success of energy access policies.

  9. Monitoring the Damage State of Fiber Reinforced Composites Using an FBG Network for Failure Prediction

    Directory of Open Access Journals (Sweden)

    Esat Selim Kocaman

    2017-01-01

    Full Text Available A structural health monitoring (SHM study of biaxial glass fibre-reinforced epoxy matrix composites under a constant, high strain uniaxial fatigue loading is performed using fibre Bragg grating (FBG optical sensors embedded in composites at various locations to monitor the evolution of local strains, thereby understanding the damage mechanisms. Concurrently, the temperature changes of the samples during the fatigue test have also been monitored at the same locations. Close to fracture, significant variations in local temperatures and strains are observed, and it is shown that the variations in temperature and strain can be used to predict imminent fracture. It is noted that the latter information cannot be obtained using external strain gages, which underlines the importance of the tracking of local strains internally.

  10. [Use of a monitoring tool for growth and development in Brazilian children - systematic literature review].

    Science.gov (United States)

    de Almeida, Ana Claudia; Mendes, Larissa da Costa; Sad, Izabela Rocha; Ramos, Eloane Gonçalves; Fonseca, Vânia Matos; Peixoto, Maria Virginia Marques

    2016-01-01

    To assess the use of a health monitoring tool in Brazilian children, with emphasis on the variables related to growth and development, which are crucial aspects of child health care. A systematic review of the literature was carried out in studies performed in Brazil, using the Cochrane Brazil, Lilacs, SciELO and Medline databases. The descriptors and keywords used were "growth and development", "child development", "child health record", "child health handbook", "health record and child" and "child handbook", as well as the equivalent terms in Portuguese. Studies were screened by title and summary and those considered eligible were read in full. Sixty-eight articles were identified and eight articles were included in the review, as they carried out a quantitative analysis of the filling out of information. Five studies assessed the completion of the Child's Health Record and three of the Child's Health Handbook. All articles concluded that the information was not properly recorded. Growth monitoring charts were rarely filled out, reaching 96.3% in the case of weight for age. The use of the BMI chart was not reported, despite the growing rates of childhood obesity. Only two studies reported the completion of development milestones and, in these, the milestones were recorded in approximately 20% of the verified tools. The results of the assessed articles disclosed underutilization of the tool and reflect low awareness by health professionals regarding the recording of information in the child's health monitoring document. Copyright © 2015 Sociedade de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  11. Geographical information systems as a tool for monitoring tobacco industry advertising.

    Science.gov (United States)

    Vardavas, C I; Connolly, G N; Kafatos, A G

    2009-06-01

    Although the use of a geographical information systems (GIS) approach is usually applied to epidemiological disease outbreaks and environmental exposure mapping, it has significant potential as a tobacco control research tool in monitoring point-of-purchase (POP) tobacco advertising. An ecological study design approach was applied so as to primarily evaluate and interpret the spatial density and intensity of POP and tobacco industry advertisements within advertisements per POP (range 0-25) were noted, and 80% of them were below child height. The GIS protocol identified that kiosks, that were excepted from the Greek ban on tobacco advertising, in comparison to other POP, were found not only to be closer and visible from the school gates (44.1% vs 10.8%, padvertisements (8 (5) vs 5 (3), padvertising on a large population-based scale and implies its use as a standardised method for monitoring tobacco industry strategies and tobacco control efforts.

  12. Laboratory tools for diagnosis and monitoring response in patients with chronic myeloid leukemia.

    Science.gov (United States)

    Tohami, Tali; Nagler, Arnon; Amariglio, Ninette

    2012-08-01

    Chronic myeloid leukemia (CML) is a clonal hematological disease that represents 15-20% of all adult leukemia cases. The study and treatment of CML has contributed pivotal advances to translational medicine and cancer therapy. The discovery that a single chromosomal abnormality, the Philadelphia (Ph) chromosome, is responsible for the etiology of this disease was a milestone for treating and understanding CML. Subsequently, CML became the first disease for which allogeneic bone marrow transplantation is the treatment of choice. Currently, CML is one of the few diseases where treatment targeted against the chromosomal abnormality is the sole frontline therapy for newly diagnosed patients. The use of directed therapy for CML challenged disease monitoring during treatment and led to the development of definitions that document response and predict relapse sooner than the former routine methods. These methods relied on classical cytogenetics through molecular cytogenetics (FISH) and, finally, on molecular monitoring assays. This review discusses the laboratory tools used for diagnosing CML, for monitoring during treatment, and for assessing remission or relapse. The advantages and disadvantages of each test, the common definition of response levels, and the efforts to standardize molecular monitoring for CML patient management are discussed.

  13. WLCG transfers dashboard: a unified monitoring tool for heterogeneous data transfers

    International Nuclear Information System (INIS)

    Andreeva, J; Beche, A; Saiz, P; Tuckett, D; Belov, S; Kadochnikov, I

    2014-01-01

    The Worldwide LHC Computing Grid provides resources for the four main virtual organizations. Along with data processing, data distribution is the key computing activity on the WLCG infrastructure. The scale of this activity is very large, the ATLAS virtual organization (VO) alone generates and distributes more than 40 PB of data in 100 million files per year. Another challenge is the heterogeneity of data transfer technologies. Currently there are two main alternatives for data transfers on the WLCG: File Transfer Service and XRootD protocol. Each LHC VO has its own monitoring system which is limited to the scope of that particular VO. There is a need for a global system which would provide a complete cross-VO and cross-technology picture of all WLCG data transfers. We present a unified monitoring tool – WLCG Transfers Dashboard – where all the VOs and technologies coexist and are monitored together. The scale of the activity and the heterogeneity of the system raise a number of technical challenges. Each technology comes with its own monitoring specificities and some of the VOs use several of these technologies. This paper describes the implementation of the system with particular focus on the design principles applied to ensure the necessary scalability and performance, and to easily integrate any new technology providing additional functionality which might be specific to that technology.

  14. WLCG Transfers Dashboard: a Unified Monitoring Tool for Heterogeneous Data Transfers

    Science.gov (United States)

    Andreeva, J.; Beche, A.; Belov, S.; Kadochnikov, I.; Saiz, P.; Tuckett, D.

    2014-06-01

    The Worldwide LHC Computing Grid provides resources for the four main virtual organizations. Along with data processing, data distribution is the key computing activity on the WLCG infrastructure. The scale of this activity is very large, the ATLAS virtual organization (VO) alone generates and distributes more than 40 PB of data in 100 million files per year. Another challenge is the heterogeneity of data transfer technologies. Currently there are two main alternatives for data transfers on the WLCG: File Transfer Service and XRootD protocol. Each LHC VO has its own monitoring system which is limited to the scope of that particular VO. There is a need for a global system which would provide a complete cross-VO and cross-technology picture of all WLCG data transfers. We present a unified monitoring tool - WLCG Transfers Dashboard - where all the VOs and technologies coexist and are monitored together. The scale of the activity and the heterogeneity of the system raise a number of technical challenges. Each technology comes with its own monitoring specificities and some of the VOs use several of these technologies. This paper describes the implementation of the system with particular focus on the design principles applied to ensure the necessary scalability and performance, and to easily integrate any new technology providing additional functionality which might be specific to that technology.

  15. A tool for the LHCb MWPC production monitoring the LNF on-line database

    CERN Document Server

    Sarti, A

    2006-01-01

    The LHCb Muon detector system is made of several (1368) Multi Wire Proportional Chambers (MWPCs). Those chambers differ in size, readout and constructing materials and are built in various countries: their assembly takes place in different sites and foresee many steps. To ensure the production quality and keep track of panels/chambers production an on-line database has been set up. This web based tool allows an easy sharing of the information: the database update is made possible trough a web interface. The update is easy and reliable. The interface helps the information sharing in different sites and helps optimizing the production rate by allowing feedback on production needs and quality between sites contributing to the production chain. The planning is made using the information on the material availability. Quality tests and crosschecks are made easier, as well as the overall production monitoring. The tool has been developed using mySQL, PHP, ROOT and PERL software languages.

  16. Managing and monitoring tuberculosis using web-based tools in combination with traditional approaches.

    Science.gov (United States)

    Chapman, Ann Ln; Darton, Thomas C; Foster, Rachel A

    2013-01-01

    Tuberculosis (TB) remains a global health emergency. Ongoing challenges include the coordination of national and international control programs, high levels of drug resistance in many parts of the world, and availability of accurate and rapid diagnostic tests. The increasing availability and reliability of Internet access throughout both affluent and resource-limited countries brings new opportunities to improve TB management and control through the integration of web-based technologies with traditional approaches. In this review, we explore current and potential future use of web-based tools in the areas of TB diagnosis, treatment, epidemiology, service monitoring, and teaching and training.

  17. Strategies for rock slope failure early warning using acoustic emission monitoring

    Science.gov (United States)

    Codeglia, D.; Dixon, N.; Fowmes, G. J.; Marcato, G.

    2015-09-01

    Research over the last two decades has led to development of a system for soil slopes monitoring based on the concept of measuring Acoustic Emission (AE). A feature of the system is the use of waveguides installed within unstable soil slopes. It has been demonstrated that the AE measured through this technique are proportional to soil displacement rate. Attention has now been focused on the prospect of using the system within rock materials. The different nature of the slope material to be monitored and its setting means that different acoustic trends are measured, and development of new approaches for their interpretation are required. A total of six sensors have been installed in two pilot sites, firstly in Italy, for monitoring of a stratified limestone slope which can threaten a nationally important road, and secondly in Austria, for monitoring of a conglomerate slope that can endanger a section of the local railway. In this paper an outline of the two trial sites is given and AE data collected are compared with other physical measurements (i.e. rainfall and temperature) and traditional geotechnical instrumentation, to give an overview of recurring AE trends. These include clear AE signatures generated by stress changes linked to increased ground water levels and high energy events generated by freeze-thaw of the rock mass.

  18. Effectiveness of Remote Patient Monitoring After Discharge of Hospitalized Patients With Heart Failure: The Better Effectiveness After Transition–Heart Failure (BEAT-HF) Randomized Clinical Trial

    Science.gov (United States)

    Ong, Michael K.; Romano, Patrick S.; Edgington, Sarah; Aronow, Harriet U.; Auerbach, Andrew D.; Black, Jeanne T.; De Marco, Teresa; Escarce, Jose J.; Evangelista, Lorraine S.; Hanna, Barbara; Ganiats, Theodore G.; Greenberg, Barry H.; Greenfield, Sheldon; Kaplan, Sherrie H.; Kimchi, Asher; Liu, Honghu; Lombardo, Dawn; Mangione, Carol M.; Sadeghi, Bahman; Sadeghi, Banafsheh; Sarrafzadeh, Majid; Tong, Kathleen; Fonarow, Gregg C.

    2016-01-01

    Importance It remains unclear whether telemonitoring approaches provide benefits for patients with heart failure (HF) after hospitalization. Objective To evaluate the effectiveness of a care transition intervention using remote patient monitoring in reducing 180-day all-cause readmissions among a broad population of older adults hospitalized with HF. Design, Setting, and Participants We randomized 1437 patients hospitalized for HF between October 12, 2011, and September 30, 2013, to the intervention arm (715 patients) or to the usual care arm (722 patients) of the Better Effectiveness After Transition–Heart Failure (BEAT-HF) study and observed them for 180 days. The dates of our study analysis were March 30, 2014, to October 1, 2015. The setting was 6 academic medical centers in California. Participants were hospitalized individuals 50 years or older who received active treatment for decompensated HF. Interventions The intervention combined health coaching telephone calls and telemonitoring. Telemonitoring used electronic equipment that collected daily information about blood pressure, heart rate, symptoms, and weight. Centralized registered nurses conducted telemonitoring reviews, protocolized actions, and telephone calls. Main outcomes and measures The primary outcome was readmission for any cause within 180 days after discharge. Secondary outcomes were all-cause readmission within 30 days, all-cause mortality at 30 and 180 days, and quality of life at 30 and 180 days. Results Among 1437 participants, the median age was 73 years. Overall, 46.2% (664 of 1437) were female, and 22.0% (316 of 1437) were African American. The intervention and usual care groups did not differ significantly in readmissions for any cause 180 days after discharge, which occurred in 50.8% (363 of 715) and 49.2% (355 of 722) of patients, respectively (adjusted hazard ratio, 1.03; 95% CI, 0.88-1.20; P = .74). In secondary analyses, there were no significant differences in 30-day

  19. Evolution of an audit and monitoring tool into an infection prevention and control process.

    Science.gov (United States)

    Denton, A; Topping, A; Humphreys, P

    2016-09-01

    In 2010, an infection prevention and control team in an acute hospital trust integrated an audit and monitoring tool (AMT) into the management regime for patients with Clostridium difficile infection (CDI). To examine the mechanisms through which the implementation of an AMT influenced the care and management of patients with CDI. A constructivist grounded theory approach was used, employing semi-structured interviews with ward staff (N=8), infection prevention and control practitioners (IPCPs) (N=7) and matrons (N=8), and subsequently a theoretical sample of senior managers (N=4). All interviews were transcribed verbatim and analysed using a constant comparison approach until explanatory categories emerged. The AMT evolved into a daily review process (DRP) that became an essential aspect of the management of all patients with CDI. Participants recognized that the DRP had positively influenced the care received by patients with CDI. Two main explanatory themes emerged to offer a framework for understanding the influence of the DRP on care management: education and learning, and the development and maintenance of relationships. The use of auditing and monitoring tools as part of a daily review process may enable ward staff, matrons, and IPCPs to improve patient outcomes and achieve the required levels of environmental hygiene if they act as a focal point for interaction, education, and collaboration. The findings offer insights into the behavioural changes and improved patient outcomes that ensue from the implementation of a DRP. Copyright © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  20. Tool for objective quantification of pulmonary sequelae in monitoring of patients with tuberculosis

    International Nuclear Information System (INIS)

    Giacomini, Guilherme; Alvarez, Matheus; Pina, Diana R. de; Bacchim Neto, Fernando A.; Pereira, Paulo C.M.; Ribeiro, Sergio M.; Miranda, Jose Ricardo de A.

    2014-01-01

    Tuberculosis (TB), caused by Mycobacterium tuberculosis, is an ancient infectious disease that remains a global health problem. Chest radiography is the method commonly employed in assessing the evolution of TB. However, lung damage quantification methods are usually performed on a computerized tomography (CT). This objective quantification is important in the radiological monitoring of the patient by assessing the progression and treatment of TB. However, precise quantification is not feasible by the number of CT examinations necessary due to the high dose subjected to the patient and high cost to the institution. The purpose of this work is to develop a tool to quantify pulmonary sequelae caused by TB through chest X-rays. Aiming the proposed objective, a computational algorithm was developed, creating a three-dimensional representation of the lungs, with regions of dilated sequelae inside. It also made the quantification of pulmonary sequelae of these patients through CT scans performed in upcoming dates, minimizing the differences in disease progression. The measurements from the two methods were compared with results suggest that the effectiveness and applicability of the developed tool, allowing lower doses radiological monitoring of the patient during treatment

  1. An Evaluation of an Assignment Management and Monitoring Tool to Support Student Assessment

    Directory of Open Access Journals (Sweden)

    Mee Chin Wee

    2006-06-01

    Full Text Available Information and communication technology (ICT has influenced many fields and revolutionized the way they function. One of the major fields is education. In institutions of higher education, lecturers rely on ICT tools such as the Internet, email, word processing and presentation software for assistance in teaching and learning. Automated assignment management is another important technique that is used in managing student assessments. However, existing systems have limited features to support assignment supervision. The aim of this paper is to present a prototype called Lightweight Assignment Management Prototype (LAMP and its evaluation. This prototype is designed to assist in the assignment monitoring process, which is not supported by existing systems. The paper starts with a description of the assignment supervision process at the higher education level. Then the tools available in supporting assignment management are reviewed. This is followed by a proposed scenario for assignment management and monitoring. The methodology used to test the prototype is then presented. A few user interfaces of the prototype’s main modules, from both the lecturers’ and the students’ perspectives, are described. Finally, the results of the evaluation are discussed.

  2. Early warning indicators for monitoring the process failure of anaerobic digestion system of food waste.

    Science.gov (United States)

    Li, Lei; He, Qingming; Wei, Yunmei; He, Qin; Peng, Xuya

    2014-11-01

    To determine reliable state parameters which could be used as early warning indicators of process failure due to the acidification of anaerobic digestion of food waste, three mesophilic anaerobic digesters of food waste with different operation conditions were investigated. Such parameters as gas production, methane content, pH, concentrations of volatile fatty acid (VFA), alkalinity and their combined indicators were evaluated. Results revealed that operation conditions significantly affect the responses of parameters and thus the optimal early warning indicators of each reactor differ from each other. None of the single indicators was universally valid for all the systems. The universally valid indicators should combine several parameters to supply complementary information. A combination of total VFA, the ratio of VFA to total alkalinity (VFA/TA) and the ratio of bicarbonate alkalinity to total alkalinity (BA/TA) can reflect the metabolism of the digesting system and realize rapid and effective early warning. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Heart failure analysis dashboard for patient's remote monitoring combining multiple artificial intelligence technologies.

    Science.gov (United States)

    Guidi, G; Pettenati, M C; Miniati, R; Iadanza, E

    2012-01-01

    In this paper we describe an Heart Failure analysis Dashboard that, combined with a handy device for the automatic acquisition of a set of patient's clinical parameters, allows to support telemonitoring functions. The Dashboard's intelligent core is a Computer Decision Support System designed to assist the clinical decision of non-specialist caring personnel, and it is based on three functional parts: Diagnosis, Prognosis, and Follow-up management. Four Artificial Intelligence-based techniques are compared for providing diagnosis function: a Neural Network, a Support Vector Machine, a Classification Tree and a Fuzzy Expert System whose rules are produced by a Genetic Algorithm. State of the art algorithms are used to support a score-based prognosis function. The patient's Follow-up is used to refine the diagnosis.

  4. Remote sensing change detection tools for natural resource managers: Understanding concepts and tradeoffs in the design of landscape monitoring projects

    Science.gov (United States)

    Robert E. Kennedy; Philip A. Townsend; John E. Gross; Warren B. Cohen; Paul Bolstad; Wang Y. Q.; Phyllis Adams

    2009-01-01

    Remote sensing provides a broad view of landscapes and can be consistent through time, making it an important tool for monitoring and managing protected areas. An impediment to broader use of remote sensing science for monitoring has been the need for resource managers to understand the specialized capabilities of an ever-expanding array of image sources and analysis...

  5. Improving health aid for a better planet: The planning, monitoring and evaluation tool (PLANET).

    Science.gov (United States)

    Sridhar, Devi; Car, Josip; Chopra, Mickey; Campbell, Harry; Woods, Ngaire; Rudan, Igor

    2015-12-01

    International development assistance for health (DAH) quadrupled between 1990 and 2012, from US$ 5.6 billion to US$ 28.1 billion. This generates an increasing need for transparent and replicable tools that could be used to set investment priorities, monitor the distribution of funding in real time, and evaluate the impact of those investments. In this paper we present a methodology that addresses these three challenges. We call this approach PLANET, which stands for planning, monitoring and evaluation tool. Fundamentally, PLANET is based on crowdsourcing approach to obtaining information relevant to deployment of large-scale programs. Information is contributed in real time by a diverse group of participants involved in the program delivery. PLANET relies on real-time information from three levels of participants in large-scale programs: funders, managers and recipients. At each level, information is solicited to assess five key risks that are most relevant to each level of operations. The risks at the level of funders involve systematic neglect of certain areas, focus on donor's interests over that of program recipients, ineffective co-ordination between donors, questionable mechanisms of delivery and excessive loss of funding to "middle men". At the level of managers, the risks are corruption, lack of capacity and/or competence, lack of information and /or communication, undue avoidance of governmental structures / preference to non-governmental organizations and exclusion of local expertise. At the level of primary recipients, the risks are corruption, parallel operations / "verticalization", misalignment with local priorities and lack of community involvement, issues with ethics, equity and/or acceptability, and low likelihood of sustainability beyond the end of the program's implementation. PLANET is intended as an additional tool available to policy-makers to prioritize, monitor and evaluate large-scale development programs. In this, it should complement

  6. French citizens monitoring ordinary birds provide tools for conservation and ecological sciences

    Science.gov (United States)

    Jiguet, Frédéric; Devictor, Vincent; Julliard, Romain; Couvet, Denis

    2012-10-01

    efficient scientific tool (numerous papers published in international peer-reviewed journals) which is furthermore highly cost-effective, with a reduced permanent staff in a state insitution coordonating the network and analysing the data, while a similar survey conducted by state staff only would cost more than one million euros annually. The future development of bio-economic dynamic models for providing scenarios of sustainable farming and logging to maintain biodiversity will further highlight the necessity of such volunteer monitoring for policy makers and decision planning. Scientific and logistic partnerships could be proposed to help developing such a monitoring scheme in China.

  7. Activation analysis of human hair as a tool for environmental pollution monitoring

    International Nuclear Information System (INIS)

    Obrusnik, I.

    1986-01-01

    Recent development and uses of neutron activation techniques for human hair analyses are reviewed. The method of neutron activation analysis (NAA) appears to have the potential to be used as a tool for environmental pollution monitoring. Principally, two types of NAA procedure are in use nowadays for multi-element analyses of human scalp hair. The more common of these is the method of instrumental neutron activation analysis (INAA) consisting in a single short-term (3 to 10 hours) exposure of hair to a beam of neutrons in a nuclear reactor, followed by two measurements of gamma-ray spectra at 2 to 3 days and 3 to 4 weeks after the irradiation. The following microelements can be commonly determined by this type of activation procedure: As, Au, Br, Cu, K, La, Na, Sb, Sm, Co, Cr, Cs, Fe, Hg, Rb, Sc, Se and Zn. The other procedure involves the use of radiochemical separation techniques and is employed for quantitative determinations of elements that are not easily determined by INAA (Mo, Cd, Ni, etc.), or in cases where there is a need to achieve the lowest possible limits of analytical determination. The accuracy of NAA techniques is strongly dependent on the hair sampling and hair sample processing methods used. The analytical error of this method may vary within the range of 5 to 15%. Its applicability as a tool for monitoring the environmental pollution level is demonstrated on an example of groups of individuals living in areas differing by the degree of environmental pollution. The use of other biological materials, such as mammalian hair, for the purpose of environmental exposure monitoring is also considered. (author)

  8. Remote monitoring as a tool in condition assessment of a highway bridge

    Science.gov (United States)

    Tantele, Elia A.; Votsis, Renos A.; Onoufriou, Toula; Milis, Marios; Kareklas, George

    2016-08-01

    The deterioration of civil infrastructure and their subsequent maintenance is a significant problem for the responsible managing authorities. The ideal scenario is to detect deterioration and/or structural problems at early stages so that the maintenance cost is kept low and the safety of the infrastructure remains undisputed. The current inspection regimes implemented mostly via visual inspection are planned at specific intervals but are not always executed on time due to shortcomings in expert personnel and finance. However the introduction of technological advances in the assessment of infrastructures provides the tools to alleviate this problem. This study describes the assessment of a highway RC bridge's structural condition using remote structural health monitoring. A monitoring plan is implemented focusing on strain measurements; as strain is a parameter influenced by the environmental conditions supplementary data are provided from temperature and wind sensors. The data are acquired using wired sensors (deployed at specific locations) which are connected to a wireless sensor unit installed at the bridge. This WSN application enables the transmission of the raw data from the field to the office for processing and evaluation. The processed data are then used to assess the condition of the bridge. This case study, which is part of an undergoing RPF research project, illustrates that remote monitoring can alleviate the problem of missing structural inspections. Additionally, shows its potential to be the main part of a fully automated smart procedure of obtaining structural data, processed them and trigger an alarm when certain undesirable conditions are met.

  9. Self-report instruments of cognitive failures as screening tools for Subjective Cognitive Impairment in older adults.

    Science.gov (United States)

    Papaliagkas, Vasileios; Papantoniou, G; Tsolaki, Magda; Moraitou, Despina

    2017-01-01

    The term "Subjective Cognitive Impairment (SCI)" is the most widely accepted term for cognitive complaints of otherwise apparently healthy older adults. It is presently clear that SCI might be a risk factor for the development of Mild Cognitive Impairment and dementia. As regards SCI measurement and potential diagnosis, several studies showed that SCI is a condition in which people score in the normal range on common tests but believe they experience cognitive decline. Hence, to assess the characteristic of the SCI subtle cognitive decline, self-report measures were developed to estimate "self-experience" of minimal decline in cognition seem the most appropriate tools. In this vein, the present study aimed at examining the capacity of the Greek version of two self-report instruments of the aforementioned type to detect SCI in community dwelling older adults. The study sample consisted of 295 participants, who were allocated into four age-groups: young adults, middle-aged adults, older adults and older-old adults. The first three groups were gender and education-matched. The participants were examined via two objective tests of the Delis-Kaplan Executive Function System (D-KEFS) which is a neuropsychological battery designed to measure executive functions. In specific, they were tested via the D-KEFS Tower Test (TT) which mainly measures "planning" function, and the D-KEFS Color-Word Interference Test (C-WIT) which primarily measures "inhibition" and "switching" functions. Both tests consist of four conditions. The participants were also asked to answer to: (a) the Cognitive Failures Questionnaire (CFQ), and (b) the Prospective and Retrospective Memory Questionnaire (PRMQ), which were designed to assess subjective estimations of everyday slips of actions and cognitive failures, and episodic memory slips in everyday life, respectively. As concerns the psychometric qualities of the two questionnaires, a single-factor structure of the Greek versions of the CFQ and the

  10. Invasive intracranial pressure monitoring is a useful adjunct in the management of severe hepatic encephalopathy associated with pediatric acute liver failure.

    Science.gov (United States)

    Kamat, Pradip; Kunde, Sachin; Vos, Miriam; Vats, Atul; Gupta, Nitika; Heffron, Thomas; Romero, Rene; Fortenberry, James D

    2012-01-01

    Pediatric acute liver failure is often accompanied by hepatic encephalopathy, cerebral edema, and raised intracranial pressure. Elevated intracranial pressure can be managed more effectively with intracranial monitoring, but acute-liver-failure-associated coagulopathy is often considered a contraindication for invasive monitoring due to risk for intracranial bleeding. We reviewed our experience with use of early intracranial pressure monitoring in acute liver failure in children listed for liver transplantation. Retrospective review of all intubated pediatric acute liver failure patients with grade III and grade IV encephalopathy requiring intracranial pressure monitoring and evaluated for potential liver transplant who were identified from an institutional liver transplant patient database from 1999 to 2009. None. A total of 14 patients were identified who met the inclusion criteria. Their ages ranged from 7 months to 20 yrs. Diagnoses of acute liver failure were infectious (three), drug-induced (seven), autoimmune hepatitis (two), and indeterminate (two). Grade III and IV encephalopathy was seen in ten (71%) and four (29%) patients, respectively. Computed tomography scans before intracranial pressure monitor placement showed cerebral edema in five (35.7%) patients. Before intracranial pressure monitor placement, fresh frozen plasma, vitamin K, and activated recombinant factor VIIa were given to all 14 patients, with significant improvement in coagulopathy (p liver transplant, with 100% surviving neurologically intact. Four of 14 (28%) patients had spontaneous recovery without liver transplant. Two of 14 (14%) patients died due to multiple organ failure before transplant. One patient had a small 9-mm intracranial hemorrhage but survived after receiving a liver transplant. No patient developed intracranial infection. In our series of patients, intracranial pressure monitoring had a low complication rate and was associated with a high survival rate despite severe

  11. Predictors of sudden death and death from pump failure in congestive heart failure are different. Analysis of 24 h Holter monitoring, clinical variables, blood chemistry, exercise test and radionuclide angiography

    DEFF Research Database (Denmark)

    Madsen, B K; Rasmussen, Verner; Hansen, J F

    1997-01-01

    One hundred and ninety consecutive patients discharged with congestive heart failure were examined with clinical evaluation, blood chemistry, 24 h Holter monitoring, exercise test and radionuclide angiography. Median left ventricular ejection fraction was 0.30, 46% were in New York Heart...

  12. A Novel Thermal-Mechanical Detection System for Reactor Pressure Vessel Bottom Failure Monitoring in Severe Accidents

    International Nuclear Information System (INIS)

    Bi, Daowei; Bu, Jiangtao; Xu, Dongling

    2013-06-01

    Following the Fukushima Daiichi nuclear accident in Japan, there is an increased need of enhanced capabilities for severe accident management (SAM) program. Among others, a reliable method for detecting reactor pressure vessel (RPV) bottom failure has been evaluated as imperative by many utility owners. Though radiation and/or temperature measurement are potential solutions by tradition, there are some limitations for them to function desirably in such severe accident as that in Japan. To provide reliable information for assessment of accident progress in SAM program, in this paper we propose a novel thermal-mechanical detection system (TMDS) for RPV bottom failure monitoring in severe accidents. The main components of TMDS include thermally sensitive element, metallic cables, tension controlled switch and main control room annunciation device. With TMDS installed, there shall be a reliable means of keeping SAM decision-makers informed whether the RPV bottom has indeed failed. Such assurance definitely guarantees enhancement of severe accident management performance and significantly improve nuclear safety and thus protect the society and people. (authors)

  13. Insulin Micropump with Embedded Pressure Sensors for Failure Detection and Delivery of Accurate Monitoring

    Directory of Open Access Journals (Sweden)

    Dimitry Dumont-Fillon

    2014-11-01

    Full Text Available Improved glycemic control with insulin pump therapy in patients with type 1 diabetes mellitus has shown gradual reductions in nephropathy and retinopathy. More recently, the emerging concept of the artificial pancreas, comprising an insulin pump coupled to a continuous glucose meter and a control algorithm, would become the next major breakthrough in diabetes care. The patient safety and the efficiency of the therapy are directly derived from the delivery accuracy of rapid-acting insulin. For this purpose, a specific precision-oriented design of micropump has been built. The device, made of a stack of three silicon wafers, comprises two check valves and a pumping membrane that is actuated against stop limiters by a piezo actuator. Two membranes comprising piezoresistive strain gauges have been implemented to measure the pressure in the pumping chamber and at the outlet of the pump. Their high sensitivity makes possible the monitoring of the pumping accuracy with a tolerance of ±5% for each individual stroke of 200 nL. The capability of these sensors to monitor priming, reservoir overpressure, reservoir emptying, outlet occlusion and valve leakage has also been studied.

  14. Tools for Trade Analysis and Open Source Information Monitoring for Non-proliferation

    International Nuclear Information System (INIS)

    Cojazzi, G.G.M.; Versino, C.; Wolfart, E.; Renda, G.; Janssens, W.A.M.; )

    2015-01-01

    The new state level approach being proposed by IAEA envisions an objective based and information driven safeguards approach utilizing all relevant information to improve the effectiveness and efficiency of safeguards. To this goal the IAEA makes also use of open source information, here broadly defined as any information that is neither classified nor proprietary. It includes, but is not limited to: media sources, government and non-governmental reports and analyzes, commercial data, and scientific/technical literature, including trade data. Within the EC support programme to IAEA, JRC has surveyed and catalogued open sources on import-export customs trade data and developed tools for supporting the use of the related databases in safeguards. The JRC software The Big Table, (TBT), supports i.a.: a) the search through a collection of reference documents relevant to trade analysis (legal/regulatory documents, technical handbooks); b) the selection of items of interests to specific verifications and c) the mapping of these items to customs commodities searchable in trade databases. In the field of open source monitoring, JRC is developing and operating a ''Nuclear Security Media Monitor'' (NSMM), which is a web-based multilingual news aggregation system that automatically collects news articles from pre-defined web sites. NSMM is a domain specific version of the general JRC-Europe Media Monitor (EMM). NSMM has been established within the EC support programme with the aim, i.e., to streamline IAEA's process of open source information monitoring. In the first part, the paper will recall the trade data sources relevant for non-proliferation and will then illustrate the main features of TBT, recently coupled with the IAEA Physical Model, and new visualization techniques applied to trade data. In the second part it will present the main aspects of the NSMM also by illustrating some of uses done at JRC. (author)

  15. Visual exploration and analysis of ionospheric scintillation monitoring data: The ISMR Query Tool

    Science.gov (United States)

    Vani, Bruno César; Shimabukuro, Milton Hirokazu; Galera Monico, João Francisco

    2017-07-01

    Ionospheric Scintillations are rapid variations on the phase and/or amplitude of a radio signal as it passes through ionospheric plasma irregularities. The ionosphere is a specific layer of the Earth's atmosphere located approximately between 50 km and 1000 km above the Earth's surface. As Global Navigation Satellite Systems (GNSS) - such as GPS, Galileo, BDS and GLONASS - use radio signals, these variations degrade their positioning service quality. Due to its location, Brazil is one of the places most affected by scintillation in the world. For that reason, ionosphere monitoring stations have been deployed over Brazilian territory since 2011 through cooperative projects between several institutions in Europe and Brazil. Such monitoring stations compose a network that generates a large amount of monitoring data everyday. GNSS receivers deployed at these stations - named Ionospheric Scintillation Monitor Receivers (ISMR) - provide scintillation indices and related signal metrics for available satellites dedicated to satellite-based navigation and positioning services. With this monitoring infrastructure, more than ten million observation values are generated and stored every day. Extracting the relevant information from this huge amount of data was a hard process and required the expertise of computer and geoscience scientists. This paper describes the concepts, design and aspects related to the implementation of the software that has been supporting research on ISMR data - the so-called ISMR Query Tool. Usability and other aspects are also presented via examples of application. This web based software has been designed and developed aiming to ensure insights over the huge amount of ISMR data that is fetched every day on an integrated platform. The software applies and adapts time series mining and information visualization techniques to extend the possibilities of exploring and analyzing ISMR data. The software is available to the scientific community through the

  16. A multi path, weather independent avalanche monitoring tool using distributed acoustic fiber optic sensing

    Science.gov (United States)

    Prokop, Alexander; Wirbel, Anna

    2013-04-01

    Information on avalanche activity is a paramount parameter in avalanche forecasting. When avalanches are released spontaneously, the risk of avalanches is very high. Triggering avalanches by artificial means, such as explosives launched from helicopter or avalanche towers, can also give information on the stability of the snow pack. Hence, monitoring of avalanches released naturally or artificially, is an important quantity in avalanche forecasting. This information is also needed when deciding whether to close or not endangered ski runs, roads or railway lines. So far monitoring systems lack certain benefits. Either they monitor only large avalanches, can only be used for single avalanche tracks or are weather/sight dependant. Therefore a new tool for avalanche- monitoring, a distributed fiber optic system, is for the first time installed and adapted for the purpose of monitoring snow avalanche activity. The method is based on an optical time domain reflectometer (OTDR) system, which dates back to the 1970`s and detects seismic vibrations and acoustic signals on a fiber optic cable that can have a length of up to 30 km. An appropriate test slope for this configuration has been found in the ski area of "Lech am Arlberg". In this work a detailed description of the theoretical background, the system implementation, the field installation, realization of tests and an investigation of the recorded data is presented. We conducted 100 tests and triggered 41 avalanches so far with a runout distances ranging from a few meters to approximately 250 meters, all of which were detected by the system, as well as the 59 not successful attempts of artificial triggering. Moreover we measured properly if critical infrastructure (in our case a ski run) was reached by the avalanches or not. The spatial distributed sensing approach allowed us to relate the amplitude and spectral content of the signals to avalanche size, avalanche speed and snow properties of the avalanches. In

  17. Usability testing of a monitoring and feedback tool to stimulate physical activity

    Directory of Open Access Journals (Sweden)

    van der Weegen S

    2014-03-01

    Full Text Available Sanne van der Weegen,1 Renée Verwey,1,2 Huibert J Tange,3 Marieke D Spreeuwenberg,1 Luc P de Witte1,2 1Department of Health Services Research, CAPHRI School for Public Health and Primary Care, Faculty of Health Medicine and Life Sciences, Maastricht University, the Netherlands; 2Research Centre Technology in Care, Zuyd University of Applied Sciences, Heerlen, the Netherlands; 3Department of General Practice, CAPHRI School for Public Health and Primary Care, Faculty of Health Medicine and Life Sciences, Maastricht University, the Netherlands Introduction: A monitoring and feedback tool to stimulate physical activity, consisting of an activity sensor, smartphone application (app, and website for patients and their practice nurses, has been developed: the 'It's LiFe!' tool. In this study the usability of the tool was evaluated by technology experts and end users (people with chronic obstructive pulmonary disease or type 2 diabetes, with ages from 40–70 years, to improve the user interfaces and content of the tool. Patients and methods: The study had four phases: 1 a heuristic evaluation with six technology experts; 2 a usability test in a laboratory by five patients; 3 a pilot in real life wherein 20 patients used the tool for 3 months; and 4 a final lab test by five patients. In both lab tests (phases 2 and 4 qualitative data were collected through a thinking-aloud procedure and video recordings, and quantitative data through questions about task complexity, text comprehensiveness, and readability. In addition, the post-study system usability questionnaire (PSSUQ was completed for the app and the website. In the pilot test (phase 3, all patients were interviewed three times and the Software Usability Measurement Inventory (SUMI was completed. Results: After each phase, improvements were made, mainly to the layout and text. The main improvement was a refresh button for active data synchronization between activity sensor, app, and server

  18. High Resolution Monitoring of River Bluff Erosion Reveals Failure Mechanisms and Geomorphically Effective Flows

    Directory of Open Access Journals (Sweden)

    Sara Ann Kelly

    2018-03-01

    Full Text Available Using a combination of Structure from Motion and time lapse photogrammetry, we document rapid river bluff erosion occurring in the Greater Blue Earth River (GBER basin, a muddy tributary to the sediment-impaired Minnesota River in south central Minnesota. Our datasets elucidated dominant bluff failure mechanisms and rates of bluff retreat in a transient system responding to ongoing streamflow increases and glacial legacy impacts. Specifically, we document the importance of fluvial scour, freeze–thaw, as well as other drivers of bluff erosion. We find that even small flows, a mere 30% of the two-year recurrence interval flow, are capable of causing bluff erosion. During our study period (2014–2017, the most erosion was associated with two large flood events with 13- and 25-year return periods. However, based on the frequency of floods and magnitude of bluff face erosion associated with floods over the last 78 years, the 1.2-year return interval flood has likely accomplished the most cumulative erosion, and is thus more geomorphically effective than larger magnitude floods. Flows in the GBER basin are nonstationary, increasing across the full range of return intervals. We find that management implications differ considerably depending on whether the bluff erosion-runoff power law exponent, γ, is greater than, equal to, or less than 1. Previous research has recommended installation of water retention sites in tributaries to the Minnesota River in order to reduce flows and sediment loading from river bluffs. Our findings support the notion that water retention would be an effective practice to reduce sediment loading and highlight the importance of managing for both runoff frequency and magnitude.

  19. Geotechnical assessment of road failure and slope monitoring along Nsukka-Adoru-Idah highway, Southeastern Nigeria.

    Science.gov (United States)

    Maduka, Raphael Iweanya; Igwe, Ogbonnaya; Ayogu, Nnadozie Onyekachi; Ayogu, Chinero Nneka; Nwachukwu, Martin

    2017-01-01

    The quality of highway pavement is greatly influenced by the subgrade materials, the general geology of the area, and the materials used for construction. Investigation into the 75-km Nsukka-Adoru-Idah highway revealed that the pavement was underlain by three lithological units-Imo, Nsukka, and Ajali formations. The geotechnical evaluation carried out in the study includes the particle size distribution, Atterberg limit, specific gravity, compaction tests, and California bearing ratio (CBR). The base course has clay/silt (7-14%), fine sand (1-4%), medium sand (6-13%), and coarse sand (65-86%), while the subgrade presented clay/silt (74-82%), fine sand (6-9%), medium sand (10-17%), and coarse sand (1-3%). The average specific gravity results for the studied base course and subgrades are 2.58 and 2.52. Liquid limit (LL) result ranges from 27 to 60%, while plastic limit (PL) ranges between 17 and 24%, and plasticity index (PI) ranges from 5 to 39%. The maximum dry density (MDD) result ranges from 1.70 to 2.10 mg/m 3 , while the optimum moisture content (OMC) for the samples ranges between 14.1 and 18.0%. The CBR result for soaked and unsoaked samples ranges from 37 to 74 and 48 to 83%, respectively. The low unsoaked CBR ( 30% and PI > 12%) failed the stipulated Nigerian standard, signifying the need for stabilization. A geotechnical model of a highway road cut generated a factor of safety of 1.45, indicating possibility of slope failure.

  20. Intrathoracic impedance and ultrasound lung comets in heart failure deterioration monitoring.

    Science.gov (United States)

    Maines, Massimiliano; Catanzariti, Domenico; Angheben, Carlo; Valsecchi, Sergio; Comisso, Jennifer; Vergara, Giuseppe

    2011-08-01

    Echographic examination of the lung surface may reveal multiple ultrasound lung comets (ULCs) originating from water-thickened interlobular septa. These images were demonstrated to be useful for noninvasive assessment of interstitial pulmonary edema. Similarly, the correlation between implantable defibrillator-measured intrathoracic impedance and pulmonary capillary wedge pressure (PCWP) was demonstrated in heart failure (HF) patients. The aims of this analysis were to assess the agreement between defibrillator-detected impedance decrease and the presence of ULCs, as well as to compare the performance of the impedance-detection algorithm and the ULCs assessment in predicting HF worsening. We studied 23 HF patients implanted with a defibrillator capable of intrathoracic impedance measurement and alerting for fluid accumulation diagnosis. At regular follow-up and at visits for HF decompensation or device alert, clinical status was assessed, chest ultrasound was performed, and PCWP was noninvasively estimated with Doppler echocardiography. During 23 ± 11 months of follow-up, 45 paired assessments of defibrillator-measured intrathoracic impedance and ULCs were performed. The number of ULCs resulted significantly correlated to the paired PCWP estimations (r = 0.917, P < 0.001) and to the impedance fluid index (r = 0.669, P < 0.001). During follow-up, 12 episodes of HF decompensation were reported in 12 patients. The impedance alert detected clinical HF deterioration with 92% sensitivity and 69% positive predictive value. The presence of ≥5 ULCs showed 83% sensitivity and 91% positive predictive value. These data demonstrate the correlation between intrathoracic impedance and the number of ULCs at chest ultrasound, and a good agreement between the defibrillator warning for fluid index and the detection of multiple ULCs. ©2011, The Authors. Journal compilation ©2011 Wiley Periodicals, Inc.

  1. Proposal for an Ultrasonic Tool to Monitor the Osseointegration of Dental Implants

    Directory of Open Access Journals (Sweden)

    José Carlos Pereira

    2007-07-01

    Full Text Available The longevity of dental implants depends on osseointegration, which providesload-bearing capacity without putting the prosthesis at risk from micromotions at theimplant-bone interface. This research involved an analysis of the viability of an ultrasonicevaluation tool to quantify osseointegration. Ultrasonic transmission is directly dependenton the difference between the acoustic impedance of materials in intimate contact witheach other. The closer their acoustic impedances the more intense their transmission.Therefore, an analysis of the ultrasonic echoes would presumably allow for a quantitativeevaluation of the bone tissue that has grown into the pores of the implant. In addition, theliterature reports that bone fracture healing can be accelerated by the application of acontrolled low-amplitude mechanical stimulus on the site of the lesion. In fact, acousticpressure waves of low-intensity pulsed ultrasound are reportedly a secure technique forpromoting mechanical stimulus without impairing the healing process. Many experimentaland clinical trials have confirmed that daily transcutaneous ultrasound applications on theinjured site are beneficial to the enhancement of fractured bone. This proposal aims tobring together the characteristics of ultrasound propagation and the positive effect ofultrasound on bone growth into a single tool that quantitatively monitors the evolution ofthe osseointegration process. The viability of a device with these features was investigatedthrough simulations and experimentally. The initial simulations were conducted to explorethe influence of waveguide shapes on the tool’s sensitivity to changes in the implantsupporting media. The waveguides were designed in two parts, one consisting of a screw-shaped part to attach to the implant and the other a conical or step-shaped part to which the ultrasonic source was fixed in the first simulations. The step-shaped waveguide proved to be the more sensitive

  2. Feature Usage Explorer: Usage Monitoring and Visualization Tool in HTML5 Based Applications

    Directory of Open Access Journals (Sweden)

    Sarunas Marciuska

    2013-10-01

    Full Text Available Feature Usage Explorer is a JavaScript library, which automatically detects features in HTML5 based applications and monitors their usage. The collected information can be visualized in a Feature Usage Diagram, which is automatically generated from an input json file. Currently, the users of Feature Usage Explorer have to design their own tool in order to generate the json file from collected usage information. This option remains viable when using the library in order not to constraint the user’s choice of preferred data storage. Feature Usage Explorer can be reused in any HTML5 based applications where an understanding of how users interact with the system is required (i.e. user experience and usability studies, human computer interaction field, or requirement prioritization area.

  3. Managing and monitoring tuberculosis using web-based tools in combination with traditional approaches

    Directory of Open Access Journals (Sweden)

    Chapman AL

    2013-11-01

    Full Text Available Ann LN Chapman,1 Thomas C Darton,2 Rachel A Foster11Department of Infection and Tropical Medicine, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, 2Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UKAbstract: Tuberculosis (TB remains a global health emergency. Ongoing challenges include the coordination of national and international control programs, high levels of drug resistance in many parts of the world, and availability of accurate and rapid diagnostic tests. The increasing availability and reliability of Internet access throughout both affluent and resource-limited countries brings new opportunities to improve TB management and control through the integration of web-based technologies with traditional approaches. In this review, we explore current and potential future use of web-based tools in the areas of TB diagnosis, treatment, epidemiology, service monitoring, and teaching and training.Keywords: tuberculosis, information communication technology, Internet

  4. Floristic Quality Index: An assessment tool for restoration projects and monitoring sites in coastal Louisiana

    Science.gov (United States)

    Cretini, K.F.; Steyer, G.D.

    2011-01-01

    The Coastwide Reference Monitoring System (CRMS) program was established to assess the effectiveness of individual coastal restoration projects and the cumulative effects of multiple projects at regional and coastwide scales. In order to make these assessments, analytical teams have been assembled for each of the primary data types sampled under the CRMS program, including vegetation, hydrology, landscape, and soils. These teams consist of scientists and support staff from the U.S. Geological Survey and other Federal agencies, the Louisiana Office of Coastal Protection and Restoration, and university academics. Each team is responsible for developing or identifying parameters, indices, or tools that can be used to assess coastal wetlands at various scales. The CRMS Vegetation Analytical Team has developed a Floristic Quality Index for coastal Louisiana to determine the quality of a wetland based on its plant species composition and abundance.

  5. Handgrip strength test as a complementary tool in monitoring asthma in daily clinical practice in children.

    Science.gov (United States)

    Latorre-Román, Pedro Ángel; Navarro-Martínez, Ana Vanesa; Mañas-Bastidas, Alfonso; García-Pinillos, Felipe

    2014-12-01

    The aim of this study was to demonstrate that handgrip strength test can discriminate the presence/absence of asthma and between intermittent and moderate persistent asthma in children. 140 children (70 healthy and 70 with asthma) completed the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) and performed the handgrip strength test. Forty-eight hours later, subjects performed spirometry. The results showed Handgrip strength was significantly lower (pstrength test was a predictive factor for asthma (cut-off at 16.84 kg) and for severity of pathology (cut-off at 15.06 kg). Handgrip strength was reduced in children with asthma. Handgrip strength was positively associated with lung capacity and quality of life. The fact that the handgrip strength test was able to discriminate between presence/absence of asthma and between intermittent and moderate persistent asthma in children suggested that this test could be used as a complementary tool in the monitoring of asthma in daily clinical practice.

  6. Reliable groundwater levels: failures and lessons learned from modeling and monitoring studies

    Science.gov (United States)

    Van Lanen, Henny A. J.

    2017-04-01

    Adequate management of groundwater resources requires an a priori assessment of impacts of intended groundwater abstractions. Usually, groundwater flow modeling is used to simulate the influence of the planned abstraction on groundwater levels. Model performance is tested by using observed groundwater levels. Where a multi-aquifer system occurs, groundwater levels in the different aquifers have to be monitored through observation wells with filters at different depths, i.e. above the impermeable clay layer (phreatic water level) and beneath (artesian aquifer level). A reliable artesian level can only be measured if the space between the outer wall of the borehole (vertical narrow shaft) and the observation well is refilled with impermeable material at the correct depth (post-drilling phase) to prevent a vertical hydraulic connection between the artesian and phreatic aquifer. We were involved in improper refilling, which led to impossibility to monitor reliable artesian aquifer levels. At the location of the artesian observation well, a freely overflowing spring was seen, which implied water leakage from the artesian aquifer affected the artesian groundwater level. Careful checking of the monitoring sites in a study area is a prerequisite to use observations for model performance assessment. After model testing the groundwater model is forced with proposed groundwater abstractions (sites, extraction rates). The abstracted groundwater volume is compensated by a reduction of groundwater flow to the drainage network and the model simulates associated groundwater tables. The drawdown of groundwater level is calculated by comparing the simulated groundwater level with and without groundwater abstraction. In lowland areas, such as vast areas of the Netherlands, the groundwater model has to consider a variable drainage network, which means that small streams only carry water during the wet winter season, and run dry during the summer. The main streams drain groundwater

  7. Validity and reliability of a pressure ulcer monitoring tool for persons with spinal cord impairment.

    Science.gov (United States)

    Thomason, Susan S; Luther, Stephen L; Powell-Cope, Gail M; Harrow, Jeffrey J; Palacios, Polly

    2014-05-01

    The purpose was to provide support for validity and reliability of the spinal cord impairment pressure ulcer monitoring tool (SCI-PUMT) to assess pressure ulcer (PrU) healing. Expert panels developed a 30-item pool, including new items and items from two established PrU healing tools, to represent potential variables for monitoring PrU healing. Subjects were prospectively assessed weekly for each variable over a 12-week period. Data collection was conducted on a cohort of inpatients and outpatients in one Spinal Cord Injury/Disorders Center in the Veterans' Health Administration. A convenience sample of Veterans (n = 66) with spinal cord impairment (SCI) was recruited. Eligible subjects had at least one PrU (n = 167) and a history of SCI for longer than 1 year. Interventions Not applicable. A change in PrU volume was calculated using VeV Measurement Documentation software and a digital imaging camera. Content validity was established for a pool of items designed to gauge PrU healing. Exploratory factor analysis (construct validity) identified a parsimonious set of seven items for inclusion in the SCI-PUMT to assess PrU healing. The SCI-PUMT was found to explain 59% of the variance of the volume across the study. Inter-rater reliability was 0.79 and intra-rater reliability ranged from 0.81 to 0.99 among research assistants. Similar levels of reliability were subsequently established among registered nurses, who used the SCI-PUMT in the clinical setting. The final version of the SCI-PUMT was determined to be valid, reliable, and sensitive in detecting PrU healing over time in Veterans with SCI.

  8. Natural variations in xenobiotic-metabolizing enzymes: developing tools for coral monitoring

    Science.gov (United States)

    Rougée, L. R. A.; Richmond, R. H.; Collier, A. C.

    2014-06-01

    The continued deterioration of coral reefs worldwide demonstrates the need to develop diagnostic tools for corals that go beyond general ecological monitoring and can identify specific stressors at sublethal levels. Cellular diagnostics present an approach to defining indicators (biomarkers) that have the potential to reflect the impact of stress at the cellular level, allowing for the detection of intracellular changes in corals prior to outright mortality. Detoxification enzymes, which may be readily induced or inhibited by environmental stressors, present such a set of indicators. However, in order to apply these diagnostic tools for the detection of stress, a detailed understanding of their normal, homeostatic levels within healthy corals must first be established. Herein, we present molecular and biochemical evidence for the expression and activity of major Phase I detoxification enzymes cytochrome P450 (CYP450), CYP2E1, and CYP450 reductase, as well as the Phase II enzymes UDP, glucuronosyltransferase (UGT), β-glucuronidase, glutathione- S-transferase (GST), and arylsulfatase C (ASC) in the coral Pocillopora damicornis. Additionally, we characterized enzyme expression and activity variations over a reproductive cycle within a coral's life history to determine natural endogenous changes devoid of stress exposure. Significant changes in enzyme activity over the coral's natural lunar reproductive cycle were observed for CYP2E1 and CYP450 reductase as well as UGT and GST, while β-glucuronidase and ASC did not fluctuate significantly. The data represent a baseline description of `health' for the expression and activity of these enzymes that can be used toward understanding the impact of environmental stressors on corals. Such knowledge can be applied to address causes of coral reef ecosystem decline and to monitor effectiveness of mitigation strategies. Achieving a better understanding of cause-and-effect relationships between putative stressors and biological

  9. TIDE TOOL: Open-Source Sea-Level Monitoring Software for Tsunami Warning Systems

    Science.gov (United States)

    Weinstein, S. A.; Kong, L. S.; Becker, N. C.; Wang, D.

    2012-12-01

    -series data in the GUI as well. This GUI also includes mouse-clickable functions such as zooming or expanding the time-series display, measuring tsunami signal characteristics (arrival time, wave period and amplitude, etc.), and removing the tide signal from the time-series data. De-tiding of the time series is necessary to obtain accurate measurements of tsunami wave parameters and to maintain accurate historical tsunami databases. With TIDE TOOL, de-tiding is accomplished with a set of tide harmonic coefficients routinely computed and updated at PTWC for many of the stations in PTWC's inventory (~570). PTWC also uses the decoded time series files (previous 3-5 days' worth) to compute on-the-fly tide coefficients. The latter is useful in cases where the station is new and a long-term stable set of tide coefficients are not available or cannot be easily obtained due to various non-astronomical effects. The international tsunami warning system is coordinated globally by the UNESCO IOC, and a number of countries in the Pacific and Indian Ocean, and Caribbean depend on Tide Tool to monitor tsunamis in real time.

  10. Tool Wear Prediction in Ti-6Al-4V Machining through Multiple Sensor Monitoring and PCA Features Pattern Recognition

    OpenAIRE

    Alessandra Caggiano

    2018-01-01

    Machining of titanium alloys is characterised by extremely rapid tool wear due to the high cutting temperature and the strong adhesion at the tool-chip and tool-workpiece interface, caused by the low thermal conductivity and high chemical reactivity of Ti alloys. With the aim to monitor the tool conditions during dry turning of Ti-6Al-4V alloy, a machine learning procedure based on the acquisition and processing of cutting force, acoustic emission and vibration sensor signals during turning i...

  11. Genome profiling (GP) as an effective tool for monitoring culture collections: a case study with Trichosporon.

    Science.gov (United States)

    Hamano, Keiichi; Ueno-Tsuji, Sachika; Tanaka, Reiko; Suzuki, Motofumi; Nishimura, Kazuko; Nishigaki, Koichi

    2012-05-01

    Species identification and classification of a large number of microbes are essential and heavy workloads in culture collections and relevant laboratories. The identification of species usually requires different methods depending on species. Therefore, the development of a method which is simple and applicable to any organisms will lessen the burdens, increase the reliability of databases and thus enhance the science on microbes. The genome profiling (GP) method, developed previously, was found effective in monitoring authenticities of all strains/species tested in culture collections and expectedly various species, which was shown by applying the GP and the conventional sequencing methods to identifying and classifying species/strains belonging to the genus Trichosporon (38 strains; 16 species). Small differences between strains (11 strains of Trichosporon asahii and 4 strains of Trichosporon coremiiforme) can be reliably discriminated by GP, which was unsuccessful in the conventional sequencing approach. Importantly, seven possible false-assignments contained in the database were all pointed out by the GP method with near-perfect correctness, showing the power of the GP method.GP was shown to be a potent tool for rapidly and correctly monitoring species and strains of fungi in culture collections owing to its simple and informative natures. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Isothermal microcalorimetry, a new tool to monitor drug action against Trypanosoma brucei and Plasmodium falciparum.

    Directory of Open Access Journals (Sweden)

    Tanja Wenzler

    Full Text Available Isothermal microcalorimetry is an established tool to measure heat flow of physical, chemical or biological processes. The metabolism of viable cells produces heat, and if sufficient cells are present, their heat production can be assessed by this method. In this study, we investigated the heat flow of two medically important protozoans, Trypanosoma brucei rhodesiense and Plasmodium falciparum. Heat flow signals obtained for these pathogens allowed us to monitor parasite growth on a real-time basis as the signals correlated with the number of viable cells. To showcase the potential of microcalorimetry for measuring drug action on pathogenic organisms, we tested the method with three antitrypanosomal drugs, melarsoprol, suramin and pentamidine and three antiplasmodial drugs, chloroquine, artemether and dihydroartemisinin, each at two concentrations on the respective parasite. With the real time measurement, inhibition was observed immediately by a reduced heat flow compared to that in untreated control samples. The onset of drug action, the degree of inhibition and the time to death of the parasite culture could conveniently be monitored over several days. Microcalorimetry is a valuable element to be added to the toolbox for drug discovery for protozoal diseases such as human African trypanosomiasis and malaria. The method could probably be adapted to other protozoan parasites, especially those growing extracellularly.

  13. Process analytical tools for monitoring, understanding, and control of pharmaceutical fluidized bed granulation: A review.

    Science.gov (United States)

    Burggraeve, Anneleen; Monteyne, Tinne; Vervaet, Chris; Remon, Jean Paul; De Beer, Thomas

    2013-01-01

    Fluidized bed granulation is a widely applied wet granulation technique in the pharmaceutical industry to produce solid dosage forms. The process involves the spraying of a binder liquid onto fluidizing powder particles. As a result, the (wetted) particles collide with each other and form larger permanent aggregates (granules). After spraying the required amount of granulation liquid, the wet granules are rapidly dried in the fluid bed granulator. Since the FDA launched its Process Analytical Technology initiative (and even before), a wide range of analytical process sensors has been used for real-time monitoring and control of fluid bed granulation processes. By applying various data analysis techniques to the multitude of data collected from the process analyzers implemented in fluid bed granulators, a deeper understanding of the process has been achieved. This review gives an overview of the process analytical technologies used during fluid bed granulation to monitor and control the process. The fundamentals of the mechanisms contributing to wet granule growth and the characteristics of fluid bed granulation processing are briefly discussed. This is followed by a detailed overview of the in-line applied process analyzers, contributing to improved fluid bed granulation understanding, modeling, control, and endpoint detection. Analysis and modeling tools enabling the extraction of the relevant information from the complex data collected during granulation and the control of the process are highlighted. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Self-assembled monolayer-based immunoassays for okadaic acid detection in seawater as monitoring tools.

    Science.gov (United States)

    Leonardo, Sandra; Toldrà, Anna; Rambla-Alegre, Maria; Fernández-Tejedor, Margarita; Andree, Karl B; Ferreres, Laura; Campbell, Katrina; Elliott, Christopher T; O'Sullivan, Ciara K; Pazos, Yolanda; Diogène, Jorge; Campàs, Mònica

    2018-02-01

    Rapid and cost-effective methods to monitor the presence of diarrhetic shellfish poisoning (DSP) toxins in seawater samples in an easy and reliable manner are required to protect human health and avoid economic losses to shellfish industry. Immunoassays for the detection of okadaic acid (OA) and dinophysistoxin-1 and dinophysistoxin-2 are developed by immobilising OA on self-assembled monothiols or dithiols in an ordered and oriented way, providing an effective limit of detection of ∼1 ng OA equiv./mL seawater. The immunoassays are applied to the analysis of the particulate fraction of seawater samples from two Catalan harbours (NW Mediterranean) and samples collected periodically from the Galician Rias (E Atlantic), as well as a reference mussel sample. Results are in agreement with LC-MS/MS and the certified values. OA concentration in seawater correlates with Dinophysis cell abundance, with a 1-2 weeks lag. The immunoassays provide powerful high-throughput analytical methods potentially applicable as alternative monitoring tools. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Focused beam reflectance measurement as a tool for in situ monitoring of the lactose crystallization process.

    Science.gov (United States)

    Pandalaneni, K; Amamcharla, J K

    2016-07-01

    Lactose accounts for about 75 and 85% of the solids in whey and deproteinized whey, respectively. Production of lactose is usually carried out by a process called crystallization. Several factors including rate of cooling, presence of impurities, and mixing speed influence the crystal size characteristics. To optimize the lactose crystallization process parameters to maximize the lactose yield, it is important to monitor the crystallization process. However, efficient in situ tools to implement at concentrations relevant to the dairy industry are lacking. The objective of the present work was to use a focused beam reflectance measurement (FBRM) system for in situ monitoring of lactose crystallization at supersaturated concentrations (wt/wt) 50, 55, and 60% at 20 and 30°C. The FBRM data were compared with Brix readings collected using a refractometer during isothermal crystallization. Chord length distributions obtained from FBRM in the ranges of lactose crystallization at various concentrations and temperatures was successfully assessed in the study. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  16. The importance of geoprocessing tools in radiometric monitoring of large areas

    International Nuclear Information System (INIS)

    Dias, Danila Carrijo da Silva; Comissao Nacional de Energia Nuclear; Silva, Nivaldo Carlos da; Alberti, Heber Luiz Caponi; Guerrero, Eder Tadeu Zenun

    2011-01-01

    Throughout history, the natural tendency of men to physically characterize their different surroundings has played an important role on the evolution of societies. Today, that tendency combined to the development of computer technologies, has allowed the accelerated growth of the Geographical Information Systems, which permits the analysis and manipulation of spatial data from diverse sources, producing geo referenced databases. The gamma radiation, one of the main contributors of human exposure to natural radiation, is known for its high penetration energy. Today, the environmental gamma radiation is measured through radiometric tracking mobile units, allowing large scale samplings and precise assessments. As a geo processing case study, a radiometric monitoring work was conducted in the town of Aguas da Prata-SP using a tracking mobile system, composed by a scintillator detector, a GPS and a computer, all installed in a vehicle. The data made of collected points and their respective doses and geographical references were captured and stored in a computer software and then inserted and treated in a GIS environment. After a cartographic base was created using a digitalized map of Aguas da Prata, the sampled points were plotted and interpolated with the cartographic base, producing two maps that demonstrate the tracking route and the gamma radiation dose range throughout the monitored area. Geo processing tools have shown great efficiency in this study, allowing agile manipulation and management of a large quantity of data, thus promoting a spatial analysis of natural radiation levels in the studied region. (author)

  17. The importance of geoprocessing tools in radiometric monitoring of large areas

    Energy Technology Data Exchange (ETDEWEB)

    Dias, Danila Carrijo da Silva [Universidade Federal de Alfenas (UNIFAL), Pocos de Caldas, MG (Brazil); Comissao Nacional de Energia Nuclear (LAPOC/CNEN-MG), Pocos de Caldas, MG (Brazil). Lab. de Pocos de Caldas; Silva, Nivaldo Carlos da; Alberti, Heber Luiz Caponi; Guerrero, Eder Tadeu Zenun, E-mail: ncsilva@cnen.gov.b, E-mail: heber@cnen.gov.b, E-mail: edertzg@cnen.gov.b [Comissao Nacional de Energia Nuclear (LAPOC/CNEN-MG), Pocos de Caldas, MG (Brazil). Lab. de Pocos de Caldas

    2011-07-01

    Throughout history, the natural tendency of men to physically characterize their different surroundings has played an important role on the evolution of societies. Today, that tendency combined to the development of computer technologies, has allowed the accelerated growth of the Geographical Information Systems, which permits the analysis and manipulation of spatial data from diverse sources, producing geo referenced databases. The gamma radiation, one of the main contributors of human exposure to natural radiation, is known for its high penetration energy. Today, the environmental gamma radiation is measured through radiometric tracking mobile units, allowing large scale samplings and precise assessments. As a geo processing case study, a radiometric monitoring work was conducted in the town of Aguas da Prata-SP using a tracking mobile system, composed by a scintillator detector, a GPS and a computer, all installed in a vehicle. The data made of collected points and their respective doses and geographical references were captured and stored in a computer software and then inserted and treated in a GIS environment. After a cartographic base was created using a digitalized map of Aguas da Prata, the sampled points were plotted and interpolated with the cartographic base, producing two maps that demonstrate the tracking route and the gamma radiation dose range throughout the monitored area. Geo processing tools have shown great efficiency in this study, allowing agile manipulation and management of a large quantity of data, thus promoting a spatial analysis of natural radiation levels in the studied region. (author)

  18. TSN Database Australia, a new tool to monitor antimicrobial resistance in Australia.

    Science.gov (United States)

    Turnidge, John; McCarthy, Laurence R; Master, Ronald N; Kepner, Douglas E; Weslock, James

    2003-01-01

    An electronic network of Australian microbiology laboratories was established to monitor the emergence and occurrence of antimicrobial resistance among clinically relevant bacteria. It is believed that the data network collected approximately 42 per cent of all antibacterial susceptibility test results generated by Australian laboratories. The network comprised 94 hospitals and 9 private commercial laboratories. Selected data elements were extracted and electronically transmitted to a central location. Upon receipt, all data were first normalised and thereafter examined for errors. Duplicate results for the same patient were identified to prevent skewing of the data toward resistance. All data passing quality assessment was staged for release of a new database release that occurred monthly. Unusual test results were first validated prior to their inclusion into the database. Using an Internet-based query tool, individual institutions could query their own data, but could only query aggregated data for other regional or national analyses. Individual patient results could be examined nor could the results of any individual institution other than their own. As of March 2002, TSN Database Australia contained 14,648,752 test results, from 2,000,394 strains (453 different taxa) and 1,213,605 patients. Since the same database concept has been established in 10 other countries (United States of America, Europe, and Canada), observations made in Australia may be compared to those observed elsewhere in the world. This article will describe TSN in greater detail, describe the query tool and some of the analyses that are possible.

  19. Verification of an emerging LCA design tool through real life performance monitoring

    Directory of Open Access Journals (Sweden)

    Eon Christine

    2017-01-01

    Full Text Available Recent research has demonstrated that low-emission houses often underperform, consuming more energy than predicted by their designs. Life cycle assessments (LCA have been employed to complement mandatory energy assessments, as they offer a more comprehensive evaluation of greenhouse gas (GHG emissions over the building lifespan. This research monitored ten energy efficient Australian houses and recorded data about energy use and photovoltaic generation over 1 year. The houses were assessed with a relatively new LCA tool in addition to the Australian mandatory house energy assessment Nationwide House Energy Rating Scheme (NatHERS. The objective of this study was twofold: first, to evaluate the results of the assessment tools compared to actual house energy requirements and second, to understand how design, renewable energy, and occupancy can impact the overall GHG emissions of the houses. The results show that energy use is positively related to NatHERS ratings, but some of the high performance houses perform poorly and there was significant variation in energy use between houses with the same ratings. The LCA revealed that modern houses have higher embodied energy than older houses, while solar panels are not always used to their full potential. This paper attributes some of the variations between theoretical and actual energy use to construction issues and occupant practices.

  20. ConfocalCheck--a software tool for the automated monitoring of confocal microscope performance.

    Directory of Open Access Journals (Sweden)

    Keng Imm Hng

    Full Text Available Laser scanning confocal microscopy has become an invaluable tool in biomedical research but regular quality testing is vital to maintain the system's performance for diagnostic and research purposes. Although many methods have been devised over the years to characterise specific aspects of a confocal microscope like measuring the optical point spread function or the field illumination, only very few analysis tools are available. Our aim was to develop a comprehensive quality assurance framework ranging from image acquisition to automated analysis and documentation. We created standardised test data to assess the performance of the lasers, the objective lenses and other key components required for optimum confocal operation. The ConfocalCheck software presented here analyses the data fully automatically. It creates numerous visual outputs indicating potential issues requiring further investigation. By storing results in a web browser compatible file format the software greatly simplifies record keeping allowing the operator to quickly compare old and new data and to spot developing trends. We demonstrate that the systematic monitoring of confocal performance is essential in a core facility environment and how the quantitative measurements obtained can be used for the detailed characterisation of system components as well as for comparisons across multiple instruments.

  1. Goniometry: is it a reliable tool to monitor passive joint range of motion in horses?

    Science.gov (United States)

    Liljebrink, Y; Bergh, A

    2010-11-01

    Simple objective assessment tools are essential to monitor the clinical efficacy of therapeutic interventions used in equine orthopaedics and rehabilitation. In human medicine, goniometry is a validated tool to quantify restrictions in joint range of motion (ROM); however, the technique is not validated in horses. To validate 2 different goniometry techniques for the measurement of passive flexion of the fetlock, carpus and hock by examining; 1) the intra- and inter-tester reliability; 2) the differences between 2 goniometry techniques and 3) differences between standing and anaesthetised horses. The study is composed of three parts: 1) the intra- and inter-tester reliability was examined on 10 horses, where each horse was assessed by 5 pairs of testers measuring ROM with a universal goniometer; 2) the differences between 2 goniometry techniques were examined on 14 horses, each assessed by 2 investigators (either working in pairs with one investigator holding the limb and the other measuring the joint angle, or working individually at the same time holding and measuring); 3) on 6 horses, the differences between standing and anaesthetised horses were assessed by 2 investigators with the same techniques as described above. Nonparametric tests (Mann-Whitney, Wilcoxon sign-rank) and Intraclass Correlation Coefficient (ICC) were used for statistical analysis (P reliability was high to excellent (ICC 0.8-1) and the inter-tester reliability low to average (ICC 0.1-0.5); 2) significant differences in joint ROM were registered in carpus and hock when measuring in pairs compared to singly and 3) significant differences in joint ROM were registered measuring anaesthetised compared to standing horses. As shown in human studies, goniometry is a promising tool in documenting passive flexion of fetlock, carpus and hock, if used by the same investigator. However, additional studies are needed for further validation. © 2010 EVJ Ltd.

  2. Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts e Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring

    NARCIS (Netherlands)

    Di Paolo, C.; Ottermanns, R.; Keiter, S.; Ait-Aissa, S.; Bluhm, K.; Brack, W.; Breitholz, M.; Buchinger, S.; Carere, M.; Chalon, C.; Cousin, X.; Dulio, V.; Escher, B.I.; Hamers, T.; Jarque, S.; Jonas, A.; Maillot-Marechal, E.; Marneffe, Y.; Nguyen, M.T.; Pandard, P.; Schifferli, A.; Schulze, T.; Seidensticker, S.; Seiler, T.B.; Tang, J.; van der Oost, R.; Vermeirssen, E.; Zounková, R.; Zwart, N.; Hollert, H.

    2016-01-01

    Bioassays are particularly useful tools to link the chemical and ecological assessments in water quality monitoring. Different methods cover a broad range of toxicity mechanisms in diverse organisms, and account for risks posed by non-target compounds and mixtures. Many tests are already applied in

  3. Are Your Students Ready for Anatomy and Physiology? Developing Tools to Identify Students at Risk for Failure

    Science.gov (United States)

    Gultice, Amy; Witham, Ann; Kallmeyer, Robert

    2015-01-01

    High failure rates in introductory college science courses, including anatomy and physiology, are common at institutions across the country, and determining the specific factors that contribute to this problem is challenging. To identify students at risk for failure in introductory physiology courses at our open-enrollment institution, an online…

  4. Review and Analysis of Existing Mobile Phone Apps to Support Heart Failure Symptom Monitoring and Self-Care Management Using the Mobile Application Rating Scale (MARS).

    Science.gov (United States)

    Masterson Creber, Ruth M; Maurer, Mathew S; Reading, Meghan; Hiraldo, Grenny; Hickey, Kathleen T; Iribarren, Sarah

    2016-06-14

    Heart failure is the most common cause of hospital readmissions among Medicare beneficiaries and these hospitalizations are often driven by exacerbations in common heart failure symptoms. Patient collaboration with health care providers and decision making is a core component of increasing symptom monitoring and decreasing hospital use. Mobile phone apps offer a potentially cost-effective solution for symptom monitoring and self-care management at the point of need. The purpose of this review of commercially available apps was to identify and assess the functionalities of patient-facing mobile health apps targeted toward supporting heart failure symptom monitoring and self-care management. We searched 3 Web-based mobile app stores using multiple terms and combinations (eg, "heart failure," "cardiology," "heart failure and self-management"). Apps meeting inclusion criteria were evaluated using the Mobile Application Rating Scale (MARS), IMS Institute for Healthcare Informatics functionality scores, and Heart Failure Society of America (HFSA) guidelines for nonpharmacologic management. Apps were downloaded and assessed independently by 2-4 reviewers, interclass correlations between reviewers were calculated, and consensus was met by discussion. Of 3636 potentially relevant apps searched, 34 met inclusion criteria. Most apps were excluded because they were unrelated to heart failure, not in English or Spanish, or were games. Interrater reliability between reviewers was high. AskMD app had the highest average MARS total (4.9/5). More than half of the apps (23/34, 68%) had acceptable MARS scores (>3.0). Heart Failure Health Storylines (4.6) and AskMD (4.5) had the highest scores for behavior change. Factoring MARS, functionality, and HFSA guideline scores, the highest performing apps included Heart Failure Health Storylines, Symple, ContinuousCare Health App, WebMD, and AskMD. Peer-reviewed publications were identified for only 3 of the 34 apps. This review suggests

  5. The TrialsTracker: Automated ongoing monitoring of failure to share clinical trial results by all major companies and research institutions

    OpenAIRE

    Powell-Smith, Anna; Goldacre, Ben

    2016-01-01

    Background: Failure to publish trial results is a prevalent ethical breach with a negative impact on patient care. Audit is an important tool for quality improvement. We set out to produce an online resource that automatically identifies the sponsors with the best and worst record for failing to share trial results. Methods: A tool was produced that identifies all completed trials from clinicaltrials.gov, searches for results in the clinicaltrials.gov registry and on PubMed, and presents summ...

  6. Continuous monitoring of an earth fissure in Chino, California, USA – a management tool

    Directory of Open Access Journals (Sweden)

    M. C. Carpenter

    2015-11-01

    -time adaptive management tool for restricting pumping if strain approaches the lower limit of strain-at-failure or a stress-strain curve deviates from the previous mostly elastic regimen.

  7. Stored CO2 and Methane Leakage Risk Assessment and Monitoring Tool Development: CO2 Capture Project Phase 2 (CCP2)

    Energy Technology Data Exchange (ETDEWEB)

    Dan Kieki

    2008-09-30

    The primary project goal is to develop and test tools for optimization of ECBM recovery and geologic storage of CO{sub 2} in coalbeds, in addition to tools for monitoring CO{sub 2} sequestration in coalbeds to support risk assessment. Three critical topics identified are (1) the integrity of coal bed methane geologic and engineered systems, (2) the optimization of the coal bed storage process, and (3) reliable monitoring and verification systems appropriate to the special conditions of CO{sub 2} storage and flow in coals.

  8. Online monitoring of stable carbon isotopes of methane in anaerobic digestion as a new tool for early warning of process instability.

    Science.gov (United States)

    Polag, D; May, T; Müller, L; König, H; Jacobi, F; Laukenmann, S; Keppler, F

    2015-12-01

    Effective control of anaerobic digestion in biogas plants requires the monitoring of process sensitive and rapid response parameters in order to ensure efficient biogas production and to prevent potential process failure. In this study, stable carbon isotopes of methane (δ(13)CCH4) produced in a full-scale continuous stirred-tank reactor were investigated as a potential new monitoring tool for this purpose. Over a six-month period with variable organic loading rates, δ(13)CCH4-values were measured online by a portable high-precision laser absorption spectrometer. During a stress period of consecutive high organic loading, δ(13)CCH4-values early indicated process changes in contrast to traditionally monitored parameters where a change was observed some five to ten days later. Comparison of the stable isotope values with data from microbial analyses showed a distinct relationship between the quantity of potentially acetoclastic methanogens and δ(13)CCH4-values. This finding indicates an association between dominant methanogenic pathways and carbon isotope values. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Protocol-driven remote monitoring of cardiac resynchronization therapy as part of a heart failure disease management strategy.

    Science.gov (United States)

    Smeets, Christophe J P; Verbrugge, Frederik H; Vranken, Julie; Van der Auwera, Jo; Mullens, Wilfried; Dupont, Matthias; Grieten, Lars; De Cannière, Hélène; Lanssens, Dorien; Vandenberk, Thijs; Storms, Valerie; Thijs, Inge M; Vandervoort, Pieter

    2017-08-14

    Cardiac resynchronisation therapy (CRT) is an established treatment for heart failure (HF) with reduced ejection fraction. CRT devices are equipped with remote monitoring functions, which are pivotal in the detection of device problems, but may also facilitate disease management. The aim of this study was to provide a comprehensive overview of the clinical interventions taken based on remote monitoring. This is a single centre observational study of consecutive CRT patients (n = 192) participating in protocol-driven remote follow-up. Incoming technical- and disease-related alerts were analysed together with subsequently triggered interventions. During 34 ± 13 months of follow-up, 1372 alert-containing notifications were received (2.53 per patient-year of follow-up), comprising 1696 unique alerts (3.12 per patient-year of follow-up). In 60%, notifications resulted in a phone contact. Technical alerts constituted 8% of incoming alerts (0.23 per patient-year of follow-up). Rhythm (1.43 per patient-year of follow-up) and bioimpedance alerts (0.98 per patient-year of follow-up) were the most frequent disease-related alerts. Notifications included a rhythm alert in 39%, which triggered referral to the emergency room (4%), outpatient cardiology clinic (36%) or general practitioner (7%), or resulted in medication changes (13%). Sole bioimpedance notifications resulted in a telephone contact in 91%, which triggered outpatient evaluation in 8% versus medication changes in 10%. Clinical outcome was excellent with 97% 1-year survival. Remote CRT follow-up resulted in 0.23 technical- versus 2.64 disease-related alerts annually. Rhythm and bioimpedance notifications constituted the majority of incoming notifications which triggered an actual intervention in 22% and 15% of cases, respectively.

  10. Damage tolerant design and condition monitoring of composite material and bondlines in wind turbine blades: Failure and crack propagation

    DEFF Research Database (Denmark)

    Pereira, Gilmar Ferreira; Mikkelsen, Lars Pilgaard; McGugan, Malcolm

    2015-01-01

    This research presents a novel method to asses a crack growing/damage event in composite material, in polymer, or in structural adhesive using Fibre Bragg Grating (FBG) sensors embedded in the host material, and its application in to a composite material structure: Wind Turbine Trailing Edge....... A Structure-Material-Sensor Finite Element Method (FEM) model was developed to simulate the Fibre Bragg Grating sensor output response, when embedded in a host material (Composite material, polymer or adhesive), during a crack growing/damage event. This Structure-Material-Sensor model provides a tool...... to analyse the application of this monitoring technique in other locations/structures, by predicting the sensor output and deciding, based on this, the optimal sensor distribution/configuration....

  11. Space Weather Products and Tools Used in Auroral Monitoring and Forecasting at CCMC/SWRC

    Science.gov (United States)

    Zheng, Yihua; Rastaetter, Lutz

    2015-01-01

    Key points discussed in this chapter are (1) the importance of aurora research to scientific advances and space weather applications, (2) space weather products at CCMC that are relevant to aurora monitoring and forecasting, and (3) the need for more effort from the whole community to achieve a better and long-lead-time forecast of auroral activity. Aurora, as manifestations of solar wind-magnetosphere-ionosphere coupling that occurs in a region of space that is relatively easy to access for sounding rockets, satellites, and other types of observational platforms, serves as a natural laboratory for studying the underlying physics of the complex system. From a space weather application perspective, auroras can cause surface charging of technological assets passing through the region, result in scintillation effects affecting communication and navigation, and cause radar cluttering that hinders military and civilian applications. Indirectly, an aurora and its currents can induce geomagnetically induced currents (GIC) on the ground, which poses major concerns for the wellbeing and operation of power grids, particularly during periods of intense geomagnetic activity. In addition, accurate auroral forecasting is desired for auroral tourism. In this chapter, we first review some of the existing auroral models and discuss past validation efforts. Such efforts are crucial in transitioning a model(s) from research to operations and for further model improvement and development that also benefits scientific endeavors. Then we will focus on products and tools that are used for auroral monitoring and forecasting at the Space Weather Research Center (SWRC). As part of the CCMC (Community Coordinated Modeling Center), SWRC has been providing space weather services since 2010.

  12. Simulating high frequency water quality monitoring data using a catchment runoff attenuation flux tool (CRAFT).

    Science.gov (United States)

    Adams, Russell; Quinn, Paul F; Perks, Matthew; Barber, Nicholas J; Jonczyk, Jennine; Owen, Gareth J

    2016-12-01

    High resolution water quality data has recently become widely available from numerous catchment based monitoring schemes. However, the models that can reproduce time series of concentrations or fluxes have not kept pace with the advances in monitoring data. Model performance at predicting phosphorus (P) and sediment concentrations has frequently been poor with models not fit for purpose except for predicting annual losses. Here, the data from the Eden Demonstration Test Catchments (DTC) project have been used to calibrate the Catchment Runoff Attenuation Flux Tool (CRAFT), a new, parsimonious model developed with the aim of modelling both the generation and attenuation of nutrients and sediments in small to medium sized catchments. The CRAFT has the ability to run on an hourly timestep and can calculate the mass of sediments and nutrients transported by three flow pathways representing rapid surface runoff, fast subsurface drainage and slow groundwater flow (baseflow). The attenuation feature of the model is introduced here; this enables surface runoff and contaminants transported via this pathway to be delayed in reaching the catchment outlet. It was used to investigate some hypotheses of nutrient and sediment transport in the Newby Beck Catchment (NBC) Model performance was assessed using a suite of metrics including visual best fit and the Nash-Sutcliffe efficiency. It was found that this approach for water quality models may be the best assessment method as opposed to using a single metric. Furthermore, it was found that, when the aim of the simulations was to reproduce the time series of total P (TP) or total reactive P (TRP) to get the best visual fit, that attenuation was required. The model will be used in the future to explore the impacts on water quality of different mitigation options in the catchment; these will include attenuation of surface runoff. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse

    Science.gov (United States)

    Zuccato, Ettore; Chiabrando, Chiara; Castiglioni, Sara; Calamari, Davide; Bagnati, Renzo; Schiarea, Silvia; Fanelli, Roberto

    2005-01-01

    Background Cocaine use seems to be increasing in some urban areas worldwide, but it is not straightforward to determine the real extent of this phenomenon. Trends in drug abuse are currently estimated indirectly, mainly by large-scale social, medical, and crime statistics that may be biased or too generic. We thus tested a more direct approach based on 'field' evidence of cocaine use by the general population. Methods Cocaine and its main urinary metabolite (benzoylecgonine, BE) were measured by mass spectrometry in water samples collected from the River Po and urban waste water treatment plants of medium-size Italian cities. Drug concentration, water flow rate, and population at each site were used to estimate local cocaine consumption. Results We showed that cocaine and BE are present, and measurable, in surface waters of populated areas. The largest Italian river, the Po, with a five-million people catchment basin, steadily carried the equivalent of about 4 kg cocaine per day. This would imply an average daily use of at least 27 ± 5 doses (100 mg each) for every 1000 young adults, an estimate that greatly exceeds official national figures. Data from waste water treatment plants serving medium-size Italian cities were consistent with this figure. Conclusion This paper shows for the first time that an illicit drug, cocaine, is present in the aquatic environment, namely untreated urban waste water and a major river. We used environmental cocaine levels for estimating collective consumption of the drug, an approach with the unique potential ability to monitor local drug abuse trends in real time, while preserving the anonymity of individuals. The method tested here – in principle extendable to other drugs of abuse – might be further refined to become a standardized, objective tool for monitoring drug abuse. PMID:16083497

  14. Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse

    Directory of Open Access Journals (Sweden)

    Bagnati Renzo

    2005-08-01

    Full Text Available Abstract Background Cocaine use seems to be increasing in some urban areas worldwide, but it is not straightforward to determine the real extent of this phenomenon. Trends in drug abuse are currently estimated indirectly, mainly by large-scale social, medical, and crime statistics that may be biased or too generic. We thus tested a more direct approach based on 'field' evidence of cocaine use by the general population. Methods Cocaine and its main urinary metabolite (benzoylecgonine, BE were measured by mass spectrometry in water samples collected from the River Po and urban waste water treatment plants of medium-size Italian cities. Drug concentration, water flow rate, and population at each site were used to estimate local cocaine consumption. Results We showed that cocaine and BE are present, and measurable, in surface waters of populated areas. The largest Italian river, the Po, with a five-million people catchment basin, steadily carried the equivalent of about 4 kg cocaine per day. This would imply an average daily use of at least 27 ± 5 doses (100 mg each for every 1000 young adults, an estimate that greatly exceeds official national figures. Data from waste water treatment plants serving medium-size Italian cities were consistent with this figure. Conclusion This paper shows for the first time that an illicit drug, cocaine, is present in the aquatic environment, namely untreated urban waste water and a major river. We used environmental cocaine levels for estimating collective consumption of the drug, an approach with the unique potential ability to monitor local drug abuse trends in real time, while preserving the anonymity of individuals. The method tested here – in principle extendable to other drugs of abuse – might be further refined to become a standardized, objective tool for monitoring drug abuse.

  15. Simulation and monitoring tools to protect disaster management facilities against earthquakes

    Science.gov (United States)

    Saito, Taiki

    2017-10-01

    The earthquakes that hit Kumamoto Prefecture in Japan on April 14 and 16, 2016 severely damaged over 180,000 houses, including over 8,000 that were completely destroyed and others that were partially damaged according to the Cabinet Office's report as of November 14, 2016 [1]. Following these earthquakes, other parts of the world have been struck by earthquakes including Italy and New Zealand as well as the central part of Tottori Prefecture in October, where the earthquake-induced collapse of buildings has led to severe damage and casualties. The earthquakes in Kumamoto Prefecture, in fact, damaged various disaster management facilities including Uto City Hall, which significantly hindered the city's evacuation and recovery operations. One of the most crucial issues in times of disaster is securing the functions of disaster management facilities such as city halls, hospitals and fire stations. To address this issue, seismic simulations are conducted on the East and the West buildings of Toyohashi City Hall using the analysis tool developed by the author, STERA_3D, with the data of the ground motion waveform prediction for the Nankai Trough earthquake provided by the Ministry of Land, Infrastructure, Transport and Tourism. As the result, it was found that the buildings have sufficient earthquake resistance. It turned out, however, that the west building is at risk for wall cracks or ceiling panel's collapse while in the east building, people would not be able to stand through the strong quakes of 7 on the seismic intensity scale and cabinets not secured to the floors or walls would fall over. Additionally, three IT strong-motion seismometers were installed in the city hall to continuously monitor vibrations. Every five minutes, the vibration data obtained by the seismometers are sent to the computers in Toyohashi University of Technology via the Internet for the analysis tools to run simulations in the cloud. If an earthquake strikes, it is able to use the results

  16. Saliva as a tool for monitoring steroid, peptide and immune markers in sport and exercise science.

    Science.gov (United States)

    Papacosta, Elena; Nassis, George P

    2011-09-01

    This paper discusses the use of saliva analysis as a tool for monitoring steroid, peptide, and immune markers of sports training. Salivary gland physiology, regarding the regulation and stimulation of saliva secretion, as well as methodological issues including saliva collection, storage and analysis are addressed in this paper. The effects of exercise on saliva composition are then considered. Exercise elicits changes in salivary levels of steroid hormones, immunoglobulins, antimicrobial proteins and enzymes. Cortisol, testosterone and dehydroepiandrosterone can be assessed in saliva, providing a non-invasive option to assess the catabolic and anabolic effects of exercise. Validation studies using blood and salivary measures of steroid hormones are addressed in this paper. Effects of acute exercise and training on salivary immunoglobulins (SIgA, SIgM, SIgG) and salivary antimicrobial proteins, including α-amylase, lysozyme and lactoferrin, are also discussed. Analysis of cortisol and testosterone in saliva may help detect the onset of non-functional overreaching and subsequently may help to prevent the development of overtraining syndrome. Assessment of salivary immunoglobulins and antimicrobial proteins has been shown to successfully represent the effects of exercise on mucosal immunity. Increases in SIgA and antimicrobial proteins concentration and/or secretion rate are associated with acute exercise whereas conversely, decreases have been reported in athletes over a training season leaving the athlete susceptible for upper respiratory tract infections. The measurement of physiological biomarkers in whole saliva can provide a significant tool for assessing the immunological and endocrinological status associated with exercise and training. Copyright © 2011 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  17. ES4LUCC: A GIS-tool for remotely monitoring landscape dynamics

    Science.gov (United States)

    Forzieri, Giovanni; Battistini, Alessandro; Catani, Filippo

    2012-12-01

    Given the potential impacts of land cover changes on surface processes, accurate mapping of landscape dynamics is a crucial task in environmental monitoring. The use of commercial software for remote sensing of landscape changes requires appropriate expertise in sensor technology and computing resources that are not always available to decision makers. This paper presents the development of an experimental prototype of a lightweight and user-friendly GIS tool - ES4LUCC - a semiautomatic software for change detection and classification of land use/cover. The tool is based on image processing techniques applied on multi-temporal remotely sensed spectral and surface model data. The GIS-based tiling approach allows to non-specialists of remote sensing to manage high-dimensional data even from low performance computing platforms. The paper synthesizes the implemented digital image processing that form the basis of ES4LUCC, including data correction, classification and change detection, map refinements. It also describes the software architecture, the main IDL modules and the integration with GIS through a tight coupling approach and.dll calling functions. The main modelling process is controlled through a powerful GUI developed as part of the ArcMap component of ESRI ArcGIS. The software is tested by using bi-temporal color-infrared ADS40 and Light detection and ranging data acquired on a 80-km transect of the Marecchia river (Italy). The outputs of ES4LUCC give an understanding of the natural- and human-induced surface processes, such as urban planning, agricultural and forest practices, fluvial dynamics and slope instability. The model provides reliable maps (90.77% overall classification accuracy) that represent useful layers for environmental landscape management.

  18. Minimization of the energy loss of nuclear power plants in case of partial in-core monitoring system failure

    Science.gov (United States)

    Zagrebaev, A. M.; Ramazanov, R. N.; Lunegova, E. A.

    2017-01-01

    In this paper we consider the optimization problem minimize of the energy loss of nuclear power plants in case of partial in-core monitoring system failure. It is possible to continuation of reactor operation at reduced power or total replacement of the channel neutron measurements, requiring shutdown of the reactor and the stock of detectors. This article examines the reconstruction of the energy release in the core of a nuclear reactor on the basis of the indications of height sensors. The missing measurement information can be reconstructed by mathematical methods, and replacement of the failed sensors can be avoided. It is suggested that a set of ‘natural’ functions determined by means of statistical estimates obtained from archival data be constructed. The procedure proposed makes it possible to reconstruct the field even with a significant loss of measurement information. Improving the accuracy of the restoration of the neutron flux density in partial loss of measurement information to minimize the stock of necessary components and the associated losses.

  19. Tools for resistance monitoring in oriental fruit moth (Lepidoptera: Tortricidae) and first assessment in Brazilian populations.

    Science.gov (United States)

    Siegwart, M; Monteiro, L B; Maugin, S; Olivares, J; Malfitano Carvalho, S; Sauphanor, B

    2011-04-01

    In southern Brazilian apple (Malus spp.) orchards, predominantly organophosphates are used to control the oriental fruit moth, Cydia molesta (Busck) (Lepidoptera: Tortricidae), but control failures often occur. Therefore the susceptibility of three C. molesta Brazilian populations was investigated to five insecticides of different groups and modes of action, in comparison with a susceptible laboratory strain mass reared in southern France for >10 yr. At the same time, comparative biochemical and genetic analysis were performed, assessing the activities of the detoxification enzymatic systems and sequencing a gene of insecticide molecular target to find out markers associated with resistance. The three Brazilian populations were significantly resistant to chlorpyrifos ethyl compared with the reference strain. One of the field populations that had been frequently exposed to deltamethrin treatments showed significant decreasing susceptibility to this compound, whereas none of the three populations had loss of susceptibility to tebufenozide and thiacloprid compared with the reference strain. All three populations had slight but significant increases of glutathione transferase and carboxylesterases activities and significant decrease of specific acetylcholinesterase activities compared with the reference. Only the most resistant population to chlorpyriphos exhibited a significantly higher mixed function oxidase activity than the reference. The acetylcholinesterase of females was significantly less inhibited by carbaryl in the Brazilian populations than in the reference strain (1.7-2.5-fold), and this difference was not expressed in the male moth. However, no mutation in the MACE locus was detected. These biological and molecular characterizations of adaptive response to insecticides in C. molesta provide tools for early detection of insecticide resistance in field populations of this pest.

  20. Crop Monitoring as a Tool for Modelling the Genesis of Millet Prices in Senegal

    Science.gov (United States)

    Jacques, D.; Marinho, E.; Defourny, P.; Waldner, F.; d'Andrimont, R.

    2015-12-01

    Food security in Sahelian countries strongly relies on the ability of markets to transfer staplesfrom surplus to deficit areas. Market failures, leading to the inefficient geographical allocation of food,are expected to emerge from high transportation costs and information asymmetries that are commonin moderately developed countries. As a result, important price differentials are observed betweenproducing and consuming areas which damages both poor producers and food insecure consumers. Itis then vital for policy makers to understand how the prices of agricultural commodities are formed byaccounting for the existing market imperfections in addition to local demand and supply considerations. To address this issue, we have gathered an unique and diversified set of data for Senegal andintegrated it in a spatially explicit model that simulates the functioning of agricultural markets, that isfully consistent with the economic theory. Our departure point is a local demand and supply modelaround each market having its catchment areas determined by the road network. We estimate the localsupply of agricultural commodities from satellite imagery while the demand is assumed to be a functionof the population living in the area. From this point on, profitable transactions between areas with lowprices to areas with high prices are simulated for different levels of per kilometer transportation costand information flows (derived from call details records i.e. mobile phone data). The simulated prices are then comparedwith the actual millet prices. Despite the parsimony of the model that estimates only two parameters, i.e. the per kilometertransportation cost and the information asymmetry resulting from low levels of mobile phone activitybetween markets, it impressively explains more than 80% of the price differentials observed in the 40markets included in the analysis. In one hand these results can be used in the assessment of the socialwelfare impacts of the further development of

  1. Monitoring granulation rate processes using three PAT tools in a pilot-scale fluidized bed.

    Science.gov (United States)

    Tok, Ai Tee; Goh, Xueping; Ng, Wai Kiong; Tan, Reginald B H

    2008-01-01

    The purpose of this research was to analyze and compare the responses of three Process Analytical Technology (PAT) techniques applied simultaneously to monitor a pilot-scale fluidized bed granulation process. Real-time measurements using focused beam reflectance measurement (Lasentec FBRM) and near-infra red spectroscopy (Bruker NIR) were taken by inserting in-line probes into the fluidized bed. Non-intrusive acoustic emission measurements (Physical Acoustic AE) were performed by attaching piezoelectric sensors on the external wall of the fluidized bed. Powder samples were collected at regular intervals during the granulation process and characterized offline using laser diffraction, scanning electron microscopy, stereo-optical microscopy and loss on drying method. PAT data comprising chord length distribution and chord count (from FBRM), absorption spectra (from NIR) and average signal levels and counts (from AE) were compared with the particle properties measured using offline samples. All three PAT techniques were able to detect the three granulation regimes or rate processes (wetting and nucleation, consolidation and growth, breakage) to varying degrees of sensitivity. Being dependent on optical signals, the sensitivities of the FBRM and NIR techniques were susceptible to fouling on probe windows. The AE technique was sensitive to background fluidizing air flows and external interferences. The sensitivity, strengths and weaknesses of the PAT techniques examined may facilitate the selection of suitable PAT tools for process development and scale-up studies.

  2. A refined Frequency Domain Decomposition tool for structural modal monitoring in earthquake engineering

    Science.gov (United States)

    Pioldi, Fabio; Rizzi, Egidio

    2017-07-01

    Output-only structural identification is developed by a refined Frequency Domain Decomposition ( rFDD) approach, towards assessing current modal properties of heavy-damped buildings (in terms of identification challenge), under strong ground motions. Structural responses from earthquake excitations are taken as input signals for the identification algorithm. A new dedicated computational procedure, based on coupled Chebyshev Type II bandpass filters, is outlined for the effective estimation of natural frequencies, mode shapes and modal damping ratios. The identification technique is also coupled with a Gabor Wavelet Transform, resulting in an effective and self-contained time-frequency analysis framework. Simulated response signals generated by shear-type frames (with variable structural features) are used as a necessary validation condition. In this context use is made of a complete set of seismic records taken from the FEMA P695 database, i.e. all 44 "Far-Field" (22 NS, 22 WE) earthquake signals. The modal estimates are statistically compared to their target values, proving the accuracy of the developed algorithm in providing prompt and accurate estimates of all current strong ground motion modal parameters. At this stage, such analysis tool may be employed for convenient application in the realm of Earthquake Engineering, towards potential Structural Health Monitoring and damage detection purposes.

  3. Ionic Conductivity Measurements-A Powerful Tool for Monitoring Polyol Reduction Reactions.

    Science.gov (United States)

    El-Sayed, Hany A; Burger, Veronika M; Miller, Melanie; Wagenbauer, Klaus; Wagenhofer, Manuel; Gasteiger, Hubert A

    2017-11-28

    The reduction of metal precursors during the polyol synthesis of metal nanoparticles was monitored by ex situ ionic conductivity measurements. Using commonly used platinum precursors (K 2 PtCl 6 , H 2 PtCl 6 , and K 2 PtCl 4 ) as well as iridium and ruthenium precursors (IrCl 3 and RuCl 3 ), we demonstrate that their reduction in ethylene glycol at elevated temperatures is accompanied by a predictable change in ionic conductivity, enabling a precise quantification of the onset temperature for their reduction. This method also allows detecting the onset temperature for the further reaction of ethylene glycol with HCl produced by the reduction of chloride-containing metal precursors (at ≈120 °C). On the basis of these findings, we show that the conversion of the metal precursor to reduced metal atoms/clusters can be precisely quantified, if the reaction occurs below 120 °C, which also enables a distinction between the stages of metal particle nucleation and growth. The latter is demonstrated by the reduction of H 2 PtCl 6 in ethylene glycol, comparing ionic conductivity measurements with transmission electron microscopy analysis. In summary, ionic conductivity measurements are a simple and straightforward tool to quantify the reduction kinetics of commonly used metal precursors in the polyol synthesis.

  4. Development of a Tool Condition Monitoring System for Impregnated Diamond Bits in Rock Drilling Applications

    Science.gov (United States)

    Perez, Santiago; Karakus, Murat; Pellet, Frederic

    2017-05-01

    The great success and widespread use of impregnated diamond (ID) bits are due to their self-sharpening mechanism, which consists of a constant renewal of diamonds acting at the cutting face as the bit wears out. It is therefore important to keep this mechanism acting throughout the lifespan of the bit. Nonetheless, such a mechanism can be altered by the blunting of the bit that ultimately leads to a less than optimal drilling performance. For this reason, this paper aims at investigating the applicability of artificial intelligence-based techniques in order to monitor tool condition of ID bits, i.e. sharp or blunt, under laboratory conditions. Accordingly, topologically invariant tests are carried out with sharp and blunt bits conditions while recording acoustic emissions (AE) and measuring-while-drilling variables. The combined output of acoustic emission root-mean-square value (AErms), depth of cut ( d), torque (tob) and weight-on-bit (wob) is then utilized to create two approaches in order to predict the wear state condition of the bits. One approach is based on the combination of the aforementioned variables and another on the specific energy of drilling. The two different approaches are assessed for classification performance with various pattern recognition algorithms, such as simple trees, support vector machines, k-nearest neighbour, boosted trees and artificial neural networks. In general, Acceptable pattern recognition rates were obtained, although the subset composed by AErms and tob excels due to the high classification performances rates and fewer input variables.

  5. [Ambulatory blood pressure monitoring is a useful tool for all patients].

    Science.gov (United States)

    de la Sierra, A

    Clinical blood pressure measurement (BP) is an occasional and imperfect way of estimating this biological variable. Ambulatory blood pressure monitoring (ABPM) is by far the best clinical tool for measuring an individual's blood pressure. Mean values over 24h, through the daytime and at night all make it more possible to predict organic damage and the future development of the disorder. ABPM enables the detection of white-coat hypertension and masked hypertension in both the diagnosis and follow-up of treated patients. Although some of the advantages of ABPM can be reproduced by more automated measurement without the presence of an observer in the clinic or self-measurement at home, there are some other elements of great interest that are unique to ABPM, such as seeing what happens to a patient's BP at night, the night time dipping pattern and short-term variability, all of which relate equally to the patient's prognosis. There is no scientific or clinical justification for denying these advantages, and ABPM should form part of the evaluation and follow-up of practically all hypertensive patients. Rather than continuing unhelpful discussions as to its availability and acceptability, we should concentrate our efforts on ensuring its universal availability and clearly explaining its advantages to both doctors and patients. Copyright © 2016 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Integrated knowledge-based tools for documenting and monitoring damages to built heritage

    Science.gov (United States)

    Cacciotti, R.

    2015-08-01

    The advancements of information technologies as applied to the most diverse fields of science define a breakthrough in the accessibility and processing of data for both expert and non-expert users. Nowadays it is possible to evidence an increasingly relevant research effort in the context of those domains, such as that of cultural heritage protection, in which knowledge mapping and sharing constitute critical prerequisites for accomplishing complex professional tasks. The aim of this paper is to outline the main results and outputs of the MONDIS research project. This project focusses on the development of integrated knowledge-based tools grounded on an ontological representation of the field of heritage conservation. The scope is to overcome the limitations of earlier databases by the application of modern semantic technologies able to integrate, organize and process useful information concerning damages to built heritage objects. In particular MONDIS addresses the need for supporting a diverse range of stakeholders (e.g. administrators, owners and professionals) in the documentation and monitoring of damages to historical constructions and in finding related remedies. The paper concentrates on the presentation of the following integrated knowledgebased components developed within the project: (I) MONDIS mobile application (plus desktop version), (II) MONDIS record explorer, (III) Ontomind profiles, (IV) knowledge matrix and (V) terminology editor. An example of practical application of the MONDIS integrated system is also provided and finally discussed.

  7. Integrated knowledge-based tools for documenting and monitoring damages to built heritage

    Directory of Open Access Journals (Sweden)

    R. Cacciotti

    2015-08-01

    Full Text Available The advancements of information technologies as applied to the most diverse fields of science define a breakthrough in the accessibility and processing of data for both expert and non-expert users. Nowadays it is possible to evidence an increasingly relevant research effort in the context of those domains, such as that of cultural heritage protection, in which knowledge mapping and sharing constitute critical prerequisites for accomplishing complex professional tasks. The aim of this paper is to outline the main results and outputs of the MONDIS research project. This project focusses on the development of integrated knowledge-based tools grounded on an ontological representation of the field of heritage conservation. The scope is to overcome the limitations of earlier databases by the application of modern semantic technologies able to integrate, organize and process useful information concerning damages to built heritage objects. In particular MONDIS addresses the need for supporting a diverse range of stakeholders (e.g. administrators, owners and professionals in the documentation and monitoring of damages to historical constructions and in finding related remedies. The paper concentrates on the presentation of the following integrated knowledgebased components developed within the project: (I MONDIS mobile application (plus desktop version, (II MONDIS record explorer, (III Ontomind profiles, (IV knowledge matrix and (V terminology editor. An example of practical application of the MONDIS integrated system is also provided and finally discussed.

  8. Stable isotope analysis as an early monitoring tool for community-scale effects of rat eradication

    Science.gov (United States)

    Nigro, Katherine M.; Hathaway, Stacie A.; Wegmann, Alex; Miller-ter Kuile, Ana; Fisher, Robert N.; Young, Hillary S.

    2017-01-01

    Invasive rats have colonized most of the islands of the world, resulting in strong negative impacts on native biodiversity and on ecosystem functions. As prolific omnivores, invasive rats can cause local extirpation of a wide range of native species, with cascading consequences that can reshape communities and ecosystems. Eradication of rats on islands is now becoming a widespread approach to restore ecosystems, and many native island species show strong numerical responses to rat eradication. However, the effect of rat eradication on other consumers can extend beyond direct numerical effects, to changes in behavior, dietary composition, and other ecological parameters. These behavioral and trophic effects may have strong cascading impacts on the ecology of restored ecosystems, but they have rarely been examined. In this study, we explore how rat eradication has affected the trophic ecology of native land crab communities. Using stable isotope analysis of rats and crabs, we demonstrate that the diet or trophic position of most crabs changed subsequent to rat eradication. Combined with the numerical recovery of two carnivorous land crab species (Geograpsus spp.), this led to a dramatic widening of the crab trophic niche following rat eradication. Given the established importance of land crabs in structuring island communities, particularly plants, this suggests an unappreciated mechanism by which rat eradication may alter island ecology. This study also demonstrates the potential for stable isotope analysis as a complementary monitoring tool to traditional techniques, with the potential to provide more nuanced assessments of the community- and ecosystem-wide effects of restoration.

  9. Assessment of respiratory disturbance index determined with a non-restrictive monitor and of autonomic nervous system parameters in heart failure patients: A pilot study.

    Science.gov (United States)

    Shimazu, Shuzo; Hirashiki, Akihiro; Kamimura, Yoshihiro; Nakano, Yoshihisa; Adachi, Shiro; Kondo, Takahisa; Murohara, Toyoaki

    2015-09-01

    There is a link between sympathetic overactivity and sleep-disordered breathing (SDB), and both of which are important indicators of the development of heart failure. To manage the increasing numbers of heart failure patients, any method used to check for them needs to be as non-invasive, simple, and cost-effective as possible. The purpose of this study is to assess screening of SDB with a non-restrictive monitor and the autonomic nervous system in heart failure patients. The subjects were 49 patients (mean age: 67 years; male: 78%) hospitalized for worsening heart failure. After stabilization with appropriate medical therapy, each patient simultaneously underwent sleep apnea syndrome (SAS) screening with the SD-101 (Kenzmedico Co. Ltd., Saitama, Japan), which is a novel, non-restrictive, sheet-like monitor for SAS screening, and assessment of heart rate variability (HRV) with a Holter monitor. In addition, we assessed daytime sleepiness by using the Epworth Sleepiness Scale. The mean respiratory disturbance index (RDI) was 21.9 events/h. Males had significantly greater RDI values than females (24.5±11.2 events/h vs. 13.0±6.2 events/h, p<0.001). RDI on SD-101 testing was closely correlated with cyclic variation of heart rate index obtained with a Holter electrocardiogram scanner (r=0.843). Although plasma brain natriuretic peptide level was not correlated with HRV, plasma norepinephrine level was moderately well correlated with the total low- to high-frequency ratio of HRV (r=0.529). SAS screening is important for heart failure patients, because absence of subjective sleepiness is not reliable in ruling out SDB. The SAS screening with SD-101 might apply for managing heart failure. Copyright © 2015 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  10. The IVOG feeding station: a tool for monitoring the individual feed intake of group-housed weanling pigs

    NARCIS (Netherlands)

    Bruininx, E.M.A.M.; Peet-Schwering, van der C.M.C.; Schrama, J.W.; Vesseur, P.C.; Everts, H.; Beynen, A.C.

    2001-01-01

    Three batches of weanling pigs (total n=310 pigs) were used in a 34-day experiment to validate the use of an IVOG? feeding station as a tool for monitoring individual feed intake of group-housed weanling pigs. An IVOG? feeding station for weanling pigs consists of a single-space dry feeder placed on

  11. Incorporating ICT Tools in an Active Engagement Strategy-Based Classroom to Promote Learning Awareness and Self-Monitoring

    Science.gov (United States)

    Kean, Ang Chooi; Embi, Mohamed Amin; Yunus, Melor Md

    2012-01-01

    The paper examines the influence of incorporating information and communication technology (ICT) tools to help learners to promote learning awareness and self-monitoring skills. An open-ended online questionnaire survey was administered to 15 course participants at the conclusion of the course. The data were analysed on the basis of the percentage…

  12. Lot quality assurance sampling to monitor supplemental immunization activity quality: an essential tool for improving performance in polio endemic countries.

    Science.gov (United States)

    Brown, Alexandra E; Okayasu, Hiromasa; Nzioki, Michael M; Wadood, Mufti Z; Chabot-Couture, Guillaume; Quddus, Arshad; Walker, George; Sutter, Roland W

    2014-11-01

    Monitoring the quality of supplementary immunization activities (SIAs) is a key tool for polio eradication. Regular monitoring data, however, are often unreliable, showing high coverage levels in virtually all areas, including those with ongoing virus circulation. To address this challenge, lot quality assurance sampling (LQAS) was introduced in 2009 as an additional tool to monitor SIA quality. Now used in 8 countries, LQAS provides a number of programmatic benefits: identifying areas of weak coverage quality with statistical reliability, differentiating areas of varying coverage with greater precision, and allowing for trend analysis of campaign quality. LQAS also accommodates changes to survey format, interpretation thresholds, evaluations of sample size, and data collection through mobile phones to improve timeliness of reporting and allow for visualization of campaign quality. LQAS becomes increasingly important to address remaining gaps in SIA quality and help focus resources on high-risk areas to prevent the continued transmission of wild poliovirus. © Crown copyright 2014.

  13. New and Improved Remotely Sensed Products and Tools for Agricultural Monitoring Applications in Support of Famine Early Warning

    Science.gov (United States)

    Budde, M. E.; Rowland, J.; Senay, G. B.; Funk, C. C.; Pedreros, D.; Husak, G. J.; Bohms, S.

    2011-12-01

    The high global food prices in 2008 led to the acknowledgement that there is a need to monitor the inter-connectivity of global and regional markets and their potential impacts on food security in many more regions than previously considered. The crisis prompted an expansion of monitoring by the Famine Early Warning Systems Network (FEWS NET) to include additional countries, beyond those where food security has long been of concern. Scientists at the U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center and the University of California Santa Barbara Climate Hazards Group have provided new and improved data products as well as visualization and analysis tools in support of this increased mandate for remote monitoring. We present a new product for measuring actual evapotranspiration (ETa) based on the implementation of a surface energy balance model and site improvements of two standard FEWS NET monitoring products: normalized difference vegetation index (NDVI) and satellite-based rainfall estimates. USGS FEWS NET has implemented a simplified surface energy balance model to produce operational ETa anomalies for Africa. During the growing season, ETa anomalies express surplus or deficit crop water use which is directly related to crop condition and biomass. The expedited Moderate Resolution Imaging Spectroradiometer (eMODIS) production system provides FEWS NET with a much improved NDVI dataset for crop and rangeland monitoring. eMODIS NDVI provides a reliable data stream with a vastly improved spatial resolution (250-m) and short latency period (less than 12 hours) which allows for better operational vegetation monitoring. FEWS NET uses satellite rainfall estimates as inputs for monitoring agricultural food production. By combining high resolution (0.05 deg) rainfall mean fields with Tropical Rainfall Measuring Mission rainfall estimates and infrared temperature data, we provide pentadal (5-day) rainfall fields suitable for crop

  14. Enhancement of Physics-of-Failure Prognostic Models with System Level Features

    National Research Council Canada - National Science Library

    Kacprzynski, Gregory

    2002-01-01

    .... The novelty in the current prognostic tool development is that predictions are made through the fusion of stochastic physics-of-failure models, relevant system or component level health monitoring...

  15. Insights into the HyPer biosensor as molecular tool for monitoring cellular antioxidant capacity.

    Science.gov (United States)

    Hernández, Helen; Parra, Alejandra; Tobar, Nicolas; Molina, Jessica; Kallens, Violeta; Hidalgo, Miltha; Varela, Diego; Martínez, Jorge; Porras, Omar

    2018-06-01

    Aerobic metabolism brings inexorably the production of reactive oxygen species (ROS), which are counterbalanced by intrinsic antioxidant defenses avoiding deleterious intracellular effects. Redox balance is the resultant of metabolic functioning under environmental inputs (i.e. diet, pollution) and the activity of intrinsic antioxidant machinery. Monitoring of intracellular hydrogen peroxide has been successfully achieved by redox biosensor advent; however, to track the intrinsic disulfide bond reduction capacity represents a fundamental piece to understand better how redox homeostasis is maintained in living cells. In the present work, we compared the informative value of steady-state measurements and the kinetics of HyPer, a H 2 O 2 -sensitive fluorescent biosensor, targeted at the cytosol, mitochondrion and endoplasmic reticulum. From this set of data, biosensor signal recovery from an oxidized state raised as a suitable parameter to discriminate reducing capacity of a close environment. Biosensor recovery was pH-independent, condition demonstrated by experiments on pH-clamped cells, and sensitive to pharmacological perturbations of enzymatic disulfide reduction. Also, ten human cell lines were characterized according their H 2 O 2 -pulse responses, including their capacity to reduce disulfide bonds evaluated in terms of their migratory capacity. Finally, cellular migration experiments were conducted to study whether migratory efficiency was associated with the disulfide reduction activity. The migration efficiency of each cell type correlates with the rate of signal recovery measured from the oxidized biosensor. In addition, HyPer-expressing cells treated with N-acetyl-cysteine had accelerated recovery rates and major migratory capacities, both reversible effects upon treatment removal. Our data demonstrate that the HyPer signal recovery offers a novel methodological tool to track the cellular impact of redox active biomolecules. Copyright © 2018 The Authors

  16. DNA profiling, telomere analysis and antioxidant properties as tools for monitoring ex situ seed longevity.

    Science.gov (United States)

    Donà, M; Balestrazzi, A; Mondoni, A; Rossi, G; Ventura, L; Buttafava, A; Macovei, A; Sabatini, M E; Valassi, A; Carbonera, D

    2013-05-01

    The germination test currently represents the most used method to assess seed viability in germplasm banks, despite the difficulties caused by the occurrence of seed dormancy. Furthermore, seed longevity can vary considerably across species and populations from different environments, and studies related to the eco-physiological processes underlying such variations are still limited in their depth. The aim of the present work was the identification of reliable molecular markers that might help in monitoring seed deterioration. Dry seeds were subjected to artificial ageing and collected at different time points for molecular/biochemical analyses. DNA damage was measured using the RAPD (random amplified polymorphic DNA) approach while the seed antioxidant profile was obtained using both the DPPH (1,1-diphenyl, 2-picrylhydrazyl) assay and the Folin-Ciocalteu reagent method. Electron paramagnetic resonance (EPR) provided profiles of free radicals. Quantitative real-time polymerase chain reaction (QRT-PCR) was used to assess the expression profiles of the antioxidant genes MT2 (type 2 metallothionein) and SOD (superoxide dismutase). A modified QRT-PCR protocol was used to determine telomere length. The RAPD profiles highlighted different capacities of the two Silene species to overcome DNA damage induced by artificial ageing. The antioxidant profiles of dry and rehydrated seeds revealed that the high-altitude taxon Silene acaulis was characterized by a lower antioxidant specific activity. Significant upregulation of the MT2 and SOD genes was observed only in the rehydrated seeds of the low-altitude species. Rehydration resulted in telomere lengthening in both Silene species. Different seed viability markers have been selected for plant species showing inherent variation of seed longevity. RAPD analysis, quantification of redox activity of non-enzymatic antioxidant compounds and gene expression profiling provide deeper insights to study seed viability during storage

  17. Relevance of chest sonography in the diagnosis of acute respiratory failure: Comparison with current diagnostic tools in intensive care units

    Directory of Open Access Journals (Sweden)

    Rasha Daabis

    2014-10-01

    Conclusions: Lung ultrasound provided an immediate diagnosis of the underlying etiology of acute respiratory failure in most cases; it can therefore be added to the armamentarium of ICU where urgent decisions are needed for rapid diagnosis and management of patients with ARF.

  18. Stroma-supported progenitor production as a prognostic tool for graft failure following autologous stem cell transplantation

    NARCIS (Netherlands)

    van Hennik, P. B.; Breems, D. A.; Kusadasi, N.; Slaper-Cortenbach, I. C.; van den Berg, H.; van der Lelie, H. J.; Schipperus, M. R.; Cornelissen, J. J.; Ploemacher, R. E.

    2000-01-01

    To analyse the involvement of a possible numerical or qualitative stem cell defect in the development of sustained graft failure after autologous transplantation, we have determined the graft content of CD34+ nucleated cells, colony-forming cells and cobblestone area-forming cell subsets, as well as

  19. Diagnostic power and healthcare resource consumption of a dedicated workflow algorithm designed to manage thoracic impedance alerts in heart failure patients by remote monitoring.

    Science.gov (United States)

    Ricci, Renato P; Morichelli, Loredana; Porfili, Antonio; Quarta, Laura; Sassi, Anna

    2018-03-01

    Modern cardiac implantable devices provide diagnostic information on several physiological variables which are associated with worsening heart failure, creating an opportunity for early intervention to prevent heart failure symptoms and hospitalizations. We evaluated diagnostic accuracy and workload of a remote monitoring (RM) workflow algorithm which leverages intrathoracic impedance and other device diagnostics. In our RM workflow a team of expert nurses was responsible for continuity of care, direct relationship with patients and implementation of a specific protocol to evaluate RM alerts and to limit unnecessary resource consumption. Each patient was univocally assigned to a reference nurse. End points were diagnostic accuracy, healthcare utilization, defined as any hospital admission, and actionability of alerts, defined as medication change or other clinical action. One-hundred twenty-six consecutive patients with implantable cardioverter defibrillator/cardiac resynchronization therapy defibrillator were followed for a median time of 23 months. Out of 2176 remote transmissions, 893 (41%) in 111 patients (88.1%) showed clinically relevant events triggered by 574 alerts [2.2 (95% confidence interval = 2.0-2.4) per patient per year]. Among 309 alerts with intrathoracic impedance crossing, heart failure deterioration was confirmed in 116 (37.5%). Clinical actions followed 76/116 (65.5%) true heart failure alerts and 17/193 (8.8%) false-positive alerts (P change followed 72/116 (62.1%) true heart failure alerts and 15/193 (7.8%) false-positive alerts (P < 0.001). Healthcare utilization occurred in 65.5% true heart failure alerts and in 24.9% false-positive alerts (P < 0.001). A dedicated workflow algorithm results in more focused clinical surveillance leading to prompt detection and treatment of acute heart failure events without wasting healthcare resource.

  20. Development of the Heart Failure Screening Tool (Heart-FaST) to measure barriers that impede engagement in self-care.

    Science.gov (United States)

    Cameron, Jan; Ski, Chantal F; McLennan, Skye N; Rendell, Peter G; Whitbourn, Robert J; Thompson, David R

    2014-10-01

    Screening for self-care capacity is advocated before applying educational strategies. No screening tool has been specifically developed to assess barriers that impede engagement in self-care in people with heart failure. Earlier conceptual work (InCOGNITO) identified NYHA class, mild cognitive impairment and depressive symptoms as barriers that impede engagement in HF self-care. Study aims were: 1) to develop the Heart Failure Screening Tool (Heart-FaST) as a means of assessing three critical barriers to self-care; 2) to assess the content validity of the Heart-FaST; and 3) to test the feasibility of implementing the Heart-FaST in clinical practice. The Heart-FaST was developed from barriers identified in previous research (InCOGNITO) and from expert panel consensus. Content validity was assessed by examining the proportion of experts who scored each item as relevant. The InCOGNITO study indicated that four cognitive tasks, seven emotional questions and NYHA functional class were significantly correlated with the self-care scales: maintenance, management and confidence. These factors were used to create the Heart-FaST items. Consensus on wording and items to be included in the Heart-FaST was reached after two rounds of panel discussion. All items had an item-level content validity index ≥ 0.78. High scores on each barrier (physical, cognitive and emotional functioning) suggest poor self-care and the need for more intensive disease management efforts. The Heart-FaST measures three critical barriers that impede engagement in self-care. In clinical practice this tool may assist in individually tailoring educational and support strategies to promote effective heart failure self-care. © The European Society of Cardiology 2013.

  1. Evaluation of digital photography as a tool for field monitoring in potentially inhospitable environments

    Directory of Open Access Journals (Sweden)

    K.R. Butt

    2009-05-01

    Full Text Available Efficient and accurate vegetation monitoring is essential for successful assessment of upland moorland restoration. Working conditions on open moorland may be difficult, and surveying and monitoring of vegetation problematic. Image capture by digital photography, with subsequent computer analysis, was used to monitor Calluna vulgaris post-wildfire. Problems, for example picture warp, associated with close range photography of quadrats, were overcome. Digital imagery measurements of vegetation cover showed no significant difference compared with a traditional point quadrat method.

  2. Perceptions of seniors with heart failure regarding autonomous zero-effort monitoring of physiological parameters in the smart-home environment.

    Science.gov (United States)

    Grace, Sherry L; Taherzadeh, Golnoush; Jae Chang, Isaac Sung; Boger, Jennifer; Arcelus, Amaya; Mak, Susanna; Chessex, Caroline; Mihailidis, Alex

    Technological advances are leading to the ability to autonomously monitor patient's health status in their own homes, to enable aging-in-place. To understand the perceptions of seniors with heart failure (HF) regarding smart-home systems to monitor their physiological parameters. In this qualitative study, HF outpatients were invited to a smart-home lab, where they completed a sequence of activities, during which the capacity of 5 autonomous sensing modalities was compared to gold standard measures. Afterwards, a semi-structured interview was undertaken. These were transcribed and analyzed using an interpretive-descriptive approach. Five themes emerged from the 26 interviews: (1) perceptions of technology, (2) perceived benefits of autonomous health monitoring, (3) disadvantages of autonomous monitoring, (4) lack of perceived need for continuous health monitoring, and (5) preferences for autonomous monitoring. Patient perception towards autonomous monitoring devices was positive, lending credence to zero-effort technology as a viable and promising approach. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Bench-Scale Experiments to Evaluate ERT as a Monitoring Tool for Geologic CO2 Sequestration

    Science.gov (United States)

    Breen, S. J.; Detwiler, R. L.; Carrigan, C. R.

    2010-12-01

    Field-scale studies have shown Electrical Resistivity Tomography (ERT) to be an effective tool for imaging resistivity anomalies and monitoring changing saturations in the near subsurface. Despite the challenges of implementing ERT in the deep subsurface, it has potential as a surveying technology for visualizing sequestered CO2, in part because it can be localized within the target reservoir. Currently, the technology is being evaluated as part of a geologic sequestration project in Cranfield, MS, where supercritical CO2 is injected to ten thousand feet below the surface. In support of this field-scale activity, we have designed an analog bench-scale experimental system to further evaluate the ability of ERT to quantify both the volume and spatial distribution of gas injected into a saline aquifer. Our translucent sand chambers measure 58cm x 30cm x 1cm and are lined with twenty-one stainless steel electrodes on each long side, inserted into a nonconductive plastic gasket. We fill the chamber with quartz sand with different grain sizes with a filling procedure that generates small-scale layering within the injection zone, which is overlain by a fine-grained layer that serves as a capillary barrier. Prior to gas injection, the porous medium is saturated with a low resistivity salt solution. We then inject gas into the bottom of the injection zone. Buoyant forces drive gas migration into the chamber, resulting in a combination of small-scale trapping in horizontal layers, fingering between the horizontal layers, and large-scale trapping of the gas plume along the upper capillary barrier. During pauses in gas injection, a CCD camera captures high-resolution images, and an ERT data acquisition system scans the chamber. Quantitative visualization techniques are used to process the CCD images resulting in high-resolution measurements of the spatial distribution of the injected gas. These results are directly compared to resistivity fields that result from the inversion

  4. Development of tools to manage the operational monitoring and pre-design of the NPP-LV cycle

    International Nuclear Information System (INIS)

    Perusquia, R.; Arredondo S, C.; Hernandez M, J. L.; Montes T, J. L.; Castillo M, A.; Ortiz S, J. J.

    2015-09-01

    This paper presents the development of tools to facilitate the management so much, the operational monitoring of boiling water reactors (BWR) of the nuclear power plant of Laguna Verde (NPP-LV) through independent codes, and how to carry out the static calculations corresponding to process of optimized pre-design of the reference cycle next to current cycle. The progress and preliminary results obtained with the program SACal, developed at Instituto Nacional de Investigaciones Nucleares (ININ), central tool to achieve provide a management platform of the operational monitoring and pre-design of NPP-LV cycle are also described. The reached preliminary advances directed to get an Analysis center and automated design of fuel assembly cells are also presented, which together with centers or similar modules related with the fuel reloads form the key part to meet the targets set for the realization of a Management Platform of Nuclear Fuel of the NPP-LV. (Author)

  5. Development of tools for integrated monitoring and assessment of hazardous substances and their biological effects in the Baltic Sea.

    Science.gov (United States)

    Lehtonen, Kari K; Sundelin, Brita; Lang, Thomas; Strand, Jakob

    2014-02-01

    The need to develop biological effects monitoring to facilitate a reliable assessment of hazardous substances has been emphasized in the Baltic Sea Action Plan of the Helsinki Commission. An integrated chemical-biological approach is vitally important for the understanding and proper assessment of anthropogenic pressures and their effects on the Baltic Sea. Such an approach is also necessary for prudent management aiming at safeguarding the sustainable use of ecosystem goods and Services. The BEAST project (Biological Effects of Anthropogenic Chemical Stress: Tools for the Assessment of Ecosystem Health) set out to address this topic within the BONUS Programme. BEAST generated a large amount of quality-assured data on several biological effects parameters (biomarkers) in various marine species in different sub-regions of the Baltic Sea. New indicators (biological response measurement methods) and management tools (integrated indices) with regard to the integrated monitoring approach were suggested.

  6. The 24-hour report as an effective monitoring and communication tool in infection prevention and control in nursing homes.

    Science.gov (United States)

    Fisch, Jay; McNamara, Sara E; Lansing, Bonnie J; Mody, Lona

    2014-10-01

    Twenty-four-hour reports are filled out by nurses daily to monitor nursing home residents and document any changes in resident status. Semistructured interviews conducted with ICPs from 12 southeast Michigan nursing homes showed that although 24-hour reports were used, they were not standardized for infection prevention activities. Our results indicate 24-hour reports can be an effective communication tool and potentially aid in early recognition of infections and outbreaks. Published by Elsevier Inc.

  7. Self-Monitoring Tools and Student Academic Success: When Perception Matches Reality

    Science.gov (United States)

    Bercher, Debra A.

    2012-01-01

    Accurate self-monitoring of one's mastery of material is a necessary skill for student success. Without this skill students lack the awareness of when to prolong or terminate their studying for an exam, or when to modify their study strategies. Inaccurate self-monitoring can lead to false assessment of mastery, premature termination of study,…

  8. On-line bioprocess monitoring - an academic discipline or an industrial tool?

    DEFF Research Database (Denmark)

    Olsson, Lisbeth; Schulze, Ulrik; Nielsen, Jens Bredal

    1998-01-01

    Bioprocess monitoring capabilities are gaining increasing Importance bath in physiological studies and in bioprocess development, The present article focuses on on-line analytical systems since these represent the backbone of most bioprocess monitoring systems, both in academia and in industry. W...

  9. Raman Spectroscopy as a Promising Tool for Noninvasive Point-of-Care Glucose Monitoring

    NARCIS (Netherlands)

    Scholtes-Timmerman, M.J.; Bijlsma, S.; Fokkert, M.J.; Slingerland, R.; Veen, S.J.F. van

    2014-01-01

    Self-monitoring of glucose is important for managing diabetes. Noninvasive glucose monitors are not yet available, but patients would benefit highly from such a device. We present results that may lead to a novel, point-of-care noninvasive system to measure blood glucose based on Raman spectroscopy.

  10. Using Healthcare Failure Mode and Effect Analysis tool to review the process of ordering and administrating potassium chloride and potassium phosphate.

    Science.gov (United States)

    Esmail, Rosmin; Cummings, Cheryl; Dersch, Deonne; Duchscherer, Greg; Glowa, Judy; Liggett, Gail; Hulme, Terrance

    2005-01-01

    During the spring of 2004, in the Calgary Health Region (CHR) two critical incidents occurred involving patients receiving continuous renal replacement therapy (CRRT) in the intensive care unit (ICU). The outcome of these events resulted in the sudden death of both patients. The Department of Critical Care Medicine's Patient Safety and Adverse Events Team (PSAT), utilized the Healthcare Failure Mode and Effect Analysis (HFMEA) tool to review the process and conditions surrounding the ordering and administration of potassium chloride (KCI) and potassium phosphate (KPO4) in our ICUs. The HFMEA tool and the multidisciplinary team structure provided a solid framework for systematic analysis and prioritization of areas for improvement regarding the use of intravenous, high-concentration KCL and KPO4 in the ICU.

  11. Failure to Rescue as a Quality Improvement Approach in Transplantation: A First Effort to Evaluate This Tool in Pediatric Liver Transplantation.

    Science.gov (United States)

    Cramm, Shannon L; Waits, Seth A; Englesbe, Michael J; Bucuvalas, John C; Horslen, Simon P; Mazariegos, George V; Soltys, Kyle A; Anand, Ravinder; Magee, John C

    2016-04-01

    Significant intercenter variation exists in mortality and death-censored graft loss (DCGL) after transplantation. Failure to rescue (FTR, death after a major complication) is an emerging tool in quality improvement and may underlie this variation. This study is the first effort to investigate the relationship between FTR and outcomes in transplantation to assess its utility in care improvement. Using the Studies of Pediatric Liver Transplantation database, we identified 2330 children undergoing primary liver transplants at 21 centers. Centers were ranked by risk-adjusted mortality and sorted into tertiles. We then compared mortality, complications, and FTR across tertiles. Overall mortality was 4.9%, ranging from 1.4% to 8.1% in the low and high mortality tertiles (P pediatric liver transplantation recipients. This preliminary study indicates that FTR may provide a useful quality improvement tool for the field of transplantation and warrants further investigation.

  12. The use of animals as a surveillance tool for monitoring environmental health hazards, human health hazards and bioterrorism.

    Science.gov (United States)

    Neo, Jacqueline Pei Shan; Tan, Boon Huan

    2017-05-01

    This review discusses the utilization of wild or domestic animals as surveillance tools for monitoring naturally occurring environmental and human health hazards. Besides providing early warning to natural hazards, animals can also provide early warning to societal hazards like bioterrorism. Animals are ideal surveillance tools to humans because they share the same environment as humans and spend more time outdoors than humans, increasing their exposure risk. Furthermore, the biologically compressed lifespans of some animals may allow them to develop clinical signs more rapidly after exposure to specific pathogens. Animals are an excellent channel for monitoring novel and known pathogens with outbreak potential given that more than 60 % of emerging infectious diseases in humans originate as zoonoses. This review attempts to highlight animal illnesses, deaths, biomarkers or sentinel events, to remind human and veterinary public health programs that animal health can be used to discover, monitor or predict environmental health hazards, human health hazards, or bioterrorism. Lastly, we hope that this review will encourage the implementation of animals as a surveillance tool by clinicians, veterinarians, ecosystem health professionals, researchers and governments. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  13. An Observation Tool for Monitoring Social Skill Implementation in Contextually Relevant Environments

    Science.gov (United States)

    Morgan, Joseph John; Hsiao, Yun-Ju; Dobbins, Nicole; Brown, Nancy B.; Lyons, Catherine

    2015-01-01

    Skills related to social-emotional learning (SEL) are essential for college and career readiness. Failure to use appropriate skills for SEL in school is often linked to several negative academic outcomes, including rejection by school community members, academic deficits, and higher rates of problematic behavior. Social skills interventions are…

  14. Monitoring Cray Cooling Systems

    Energy Technology Data Exchange (ETDEWEB)

    Maxwell, Don E [ORNL; Ezell, Matthew A [ORNL; Becklehimer, Jeff [Cray, Inc.; Donovan, Matthew J [ORNL; Layton, Christopher C [ORNL

    2014-01-01

    While sites generally have systems in place to monitor the health of Cray computers themselves, often the cooling systems are ignored until a computer failure requires investigation into the source of the failure. The Liebert XDP units used to cool the Cray XE/XK models as well as the Cray proprietary cooling system used for the Cray XC30 models provide data useful for health monitoring. Unfortunately, this valuable information is often available only to custom solutions not accessible by a center-wide monitoring system or is simply ignored entirely. In this paper, methods and tools used to harvest the monitoring data available are discussed, and the implementation needed to integrate the data into a center-wide monitoring system at the Oak Ridge National Laboratory is provided.

  15. Key indicator tools for shallow slope failure assessment using soil chemical property signatures and soil colour variables.

    Science.gov (United States)

    Othman, Rashidi; Hasni, Shah Irani; Baharuddin, Zainul Mukrim; Hashim, Khairusy Syakirin Has-Yun; Mahamod, Lukman Hakim

    2017-10-01

    Slope failure has become a major concern in Malaysia due to the rapid development and urbanisation in the country. It poses severe threats to any highway construction industry, residential areas, natural resources and tourism activities. The extent of damages that resulted from this catastrophe can be lessened if a long-term early warning system to predict landslide prone areas is implemented. Thus, this study aims to characterise the relationship between Oxisols properties and soil colour variables to be manipulated as key indicators to forecast shallow slope failure. The concentration of each soil property in slope soil was evaluated from two different localities that consist of 120 soil samples from stable and unstable slopes located along the North-South Highway (PLUS) and East-West Highway (LPT). Analysis of variance established highly significant difference (P < 0.0001) between the locations, the total organic carbon (TOC), soil pH, cation exchange capacity (CEC), soil texture, soil chromaticity and all combinations of interactions. The overall CIELAB analysis leads to the conclusion that the CIELAB variables lightness L*, c* (Chroma) and h* (Hue) provide the most information about soil colour and other related soil properties. With regard to the relationship between colour variables and soil properties, the analysis detected that soil texture, organic carbon, iron oxide and aluminium concentration were the key factors that strongly correlate with soil colour variables at the studied area. Indicators that could be used to predict shallow slope failure were high value of L*(62), low values of c* (20) and h* (66), low concentration of iron (53 mg kg -1 ) and aluminium oxide (37 mg kg -1 ), low soil TOC (0.5%), low CEC (3.6 cmol/kg), slightly acidic soil pH (4.9), high amount of sand fraction (68%) and low amount of clay fraction (20%).

  16. Tool Wear Prediction in Ti-6Al-4V Machining through Multiple Sensor Monitoring and PCA Features Pattern Recognition.

    Science.gov (United States)

    Caggiano, Alessandra

    2018-03-09

    Machining of titanium alloys is characterised by extremely rapid tool wear due to the high cutting temperature and the strong adhesion at the tool-chip and tool-workpiece interface, caused by the low thermal conductivity and high chemical reactivity of Ti alloys. With the aim to monitor the tool conditions during dry turning of Ti-6Al-4V alloy, a machine learning procedure based on the acquisition and processing of cutting force, acoustic emission and vibration sensor signals during turning is implemented. A number of sensorial features are extracted from the acquired sensor signals in order to feed machine learning paradigms based on artificial neural networks. To reduce the large dimensionality of the sensorial features, an advanced feature extraction methodology based on Principal Component Analysis (PCA) is proposed. PCA allowed to identify a smaller number of features ( k = 2 features), the principal component scores, obtained through linear projection of the original d features into a new space with reduced dimensionality k = 2, sufficient to describe the variance of the data. By feeding artificial neural networks with the PCA features, an accurate diagnosis of tool flank wear ( VB max ) was achieved, with predicted values very close to the measured tool wear values.

  17. Tool Wear Prediction in Ti-6Al-4V Machining through Multiple Sensor Monitoring and PCA Features Pattern Recognition

    Directory of Open Access Journals (Sweden)

    Alessandra Caggiano

    2018-03-01

    Full Text Available Machining of titanium alloys is characterised by extremely rapid tool wear due to the high cutting temperature and the strong adhesion at the tool-chip and tool-workpiece interface, caused by the low thermal conductivity and high chemical reactivity of Ti alloys. With the aim to monitor the tool conditions during dry turning of Ti-6Al-4V alloy, a machine learning procedure based on the acquisition and processing of cutting force, acoustic emission and vibration sensor signals during turning is implemented. A number of sensorial features are extracted from the acquired sensor signals in order to feed machine learning paradigms based on artificial neural networks. To reduce the large dimensionality of the sensorial features, an advanced feature extraction methodology based on Principal Component Analysis (PCA is proposed. PCA allowed to identify a smaller number of features (k = 2 features, the principal component scores, obtained through linear projection of the original d features into a new space with reduced dimensionality k = 2, sufficient to describe the variance of the data. By feeding artificial neural networks with the PCA features, an accurate diagnosis of tool flank wear (VBmax was achieved, with predicted values very close to the measured tool wear values.

  18. Tool Wear Prediction in Ti-6Al-4V Machining through Multiple Sensor Monitoring and PCA Features Pattern Recognition

    Science.gov (United States)

    2018-01-01

    Machining of titanium alloys is characterised by extremely rapid tool wear due to the high cutting temperature and the strong adhesion at the tool-chip and tool-workpiece interface, caused by the low thermal conductivity and high chemical reactivity of Ti alloys. With the aim to monitor the tool conditions during dry turning of Ti-6Al-4V alloy, a machine learning procedure based on the acquisition and processing of cutting force, acoustic emission and vibration sensor signals during turning is implemented. A number of sensorial features are extracted from the acquired sensor signals in order to feed machine learning paradigms based on artificial neural networks. To reduce the large dimensionality of the sensorial features, an advanced feature extraction methodology based on Principal Component Analysis (PCA) is proposed. PCA allowed to identify a smaller number of features (k = 2 features), the principal component scores, obtained through linear projection of the original d features into a new space with reduced dimensionality k = 2, sufficient to describe the variance of the data. By feeding artificial neural networks with the PCA features, an accurate diagnosis of tool flank wear (VBmax) was achieved, with predicted values very close to the measured tool wear values. PMID:29522443

  19. Applying the self-organization feature map (SOM) algorithm to AE-based tool wear monitoring in micro-cutting

    Science.gov (United States)

    Yen, Chia-Liang; Lu, Ming-Chyuan; Chen, Jau-Liang

    2013-01-01

    This study applies a self-organization feature map (SOM) neural network to acoustic emission (AE) signal-based tool wear monitoring for a micro-milling process. An experiment was set up to collect the signal during cutting for the system development and performance analysis. The AE signal generated on the workpiece was first transformed to the frequency domain by Fast Fourier transformation (FFT), followed by feature extraction processing using the SOM algorithm. The performance verification in this study adopts a learning vector quantification (LVQ) network to evaluate the effects of the SOM algorithm on the classification performance for tool wear monitoring. To investigate the improvement achieved by the SOM algorithms, this study also investigates cases applying only the LVQ classifier and based on the class mean scatter feature selection (CMSFS) criterion and LVQ. Results show that accurate classification of the tool wear can be obtained by properly selecting features closely related to the tool wear based on the CMSFS and frequency resolution of spectral features. However, the SOM algorithms provide a more reliable methodology of reducing the effect on the system performance contributed by noise or variations in the cutting system.

  20. The internal model: A study of the relative contribution of proprioception and visual information to failure detection in dynamic systems. [sensitivity of operators versus monitors to failures

    Science.gov (United States)

    Kessel, C.; Wickens, C. D.

    1978-01-01

    The development of the internal model as it pertains to the detection of step changes in the order of control dynamics is investigated for two modes of participation: whether the subjects are actively controlling those dynamics or are monitoring an autopilot controlling them. A transfer of training design was used to evaluate the relative contribution of proprioception and visual information to the overall accuracy of the internal model. Sixteen subjects either tracked or monitored the system dynamics as a 2-dimensional pursuit display under single task conditions and concurrently with a sub-critical tracking task at two difficulty levels. Detection performance was faster and more accurate in the manual as opposed to the autopilot mode. The concurrent tracking task produced a decrement in detection performance for all conditions though this was more marked for the manual mode. The development of an internal model in the manual mode transferred positively to the automatic mode producing enhanced detection performance. There was no transfer from the internal model developed in the automatic mode to the manual mode.

  1. Self-reported recall and daily diary-recorded measures of weight monitoring adherence: associations with heart failure-related hospitalization.

    Science.gov (United States)

    Jones, Christine D; Holmes, George M; DeWalt, Darren A; Erman, Brian; Wu, Jia-Rong; Cene, Crystal W; Baker, David W; Schillinger, Dean; Ruo, Bernice; Bibbins-Domingo, Kirsten; Macabasco-O'Connell, Aurelia; Hawk, Victoria; Broucksou, Kimberly; Pignone, Michael

    2014-01-31

    Weight monitoring is an important element of HF self-care, yet the most clinically meaningful way to evaluate weight monitoring adherence is uncertain. We conducted this study to evaluate the association of (1) self-reported recall and (2) daily diary-recorded weight monitoring adherence with heart failure-related (HF-related) hospitalization. We conducted a prospective cohort study among 216 patients within a randomized trial of HF self-care training. All patients had an initial self-care training session followed by 15 calls (median) to reinforce educational material; patients were also given digital scales, instructed to weigh daily, record weights in a diary, and mail diaries back monthly. Weight monitoring adherence was assessed with a self-reported recall question administered at 12 months and dichotomized into at least daily versus less frequent weighing. Diary-recorded weight monitoring was evaluated over 12 months and dichotomized into ≥80% and review. Over 12 months in 216 patients, we identified 50 HF-related hospitalizations. Patients self-reporting daily or more frequent weight monitoring had an incidence rate ratio of 1.34 (95% CI 0.24-7.32) for HF-related hospitalizations compared to those reporting less frequent weight monitoring. Patients who completed ≥80% of weight diaries had an IRR of 0.37 (95% CI 0.18-0.75) for HF-related hospitalizations compared to patients who completed <80% of weight diaries. Self-reported recall of weight monitoring adherence was not associated with fewer HF hospitalizations. In contrast, diary-recorded adherence ≥80% of days was associated with fewer HF-related hospitalizations. Incorporating diary-based measures of weight monitoring adherence into HF self-care training programs may help to identify patients at risk for HF-related hospitalizations.

  2. Are your students ready for anatomy and physiology? Developing tools to identify students at risk for failure.

    Science.gov (United States)

    Gultice, Amy; Witham, Ann; Kallmeyer, Robert

    2015-06-01

    High failure rates in introductory college science courses, including anatomy and physiology, are common at institutions across the country, and determining the specific factors that contribute to this problem is challenging. To identify students at risk for failure in introductory physiology courses at our open-enrollment institution, an online pilot survey was administered to 200 biology students. The survey results revealed several predictive factors related to academic preparation and prompted a comprehensive analysis of college records of >2,000 biology students over a 5-yr period. Using these historical data, a model that was 91% successful in predicting student success in these courses was developed. The results of the present study support the use of surveys and similar models to identify at-risk students and to provide guidance in the development of evidence-based advising programs and pedagogies. This comprehensive approach may be a tangible step in improving student success for students from a wide variety of backgrounds in anatomy and physiology courses. Copyright © 2015 The American Physiological Society.

  3. Monitoring Subsurface Fluid Flow Using Perfluorocarbon Tracers: Another Tool Potentially Available for Subsurface Fluid Flow Assessments

    Science.gov (United States)

    Perfluorocarbon Tracers (PFTs) Complement stable Isotopes and Geochemistry for Verifying, Assessing or Modeling Fluid Flow. Geochemistry, Isotopes and PFT’s complement Geophysics to monitor and verify plume movement, leakage to shallow aquifers or surface

  4. Monitoring Natural Events Globally in Near Real-Time Using NASA's Open Web Services and Tools

    Science.gov (United States)

    Boller, Ryan A.; Ward, Kevin Alan; Murphy, Kevin J.

    2015-01-01

    Since 1960, NASA has been making global measurements of the Earth from a multitude of space-based missions, many of which can be useful for monitoring natural events. In recent years, these measurements have been made available in near real-time, making it possible to use them to also aid in managing the response to natural events. We present the challenges and ongoing solutions to using NASA satellite data for monitoring and managing these events.

  5. Quantitative monitoring of gas flooding in oil-bearing reservoirs using a pulsed neutron tool

    International Nuclear Information System (INIS)

    Ruhovets, N.; Wyatt, D.F. Jr.

    1991-01-01

    This paper reports on quantitative monitoring of gas flooding in oil bearing reservoirs which is unique in that saturations of three fluids (gas, oil and water) in the effective pore space have to be determined, while in most other applications saturation behind casing is determined only for two fluids: hydrocarbons and water. A new method has been developed to monitor gas flooding of oil reservoirs. The method is based on computing two porosities: true effective (base) porosity determined before gas flooding, and apparent effective (monitor) porosity determined after gas flooding. The base porosity is determined from open and/or cased hole porosity logs run before the flooding. When open hole logs are available, the cased hole porosity logs are calibrated against open hole log. The monitor porosity is determined from one of the cased hole porosity logs, such as a neutron log or count rate ratio curve from a pulsed neutron log run after the gas flooding. The base and monitor porosities provide determination of the hydrogen index of the reservoir fluid after the flooding. This hydrogen index is then used to determine saturation of the flood agent after flooding. Water saturation after flooding can be determined from the equation which relates neutron total cross section (Σm) to volumetric constituent cross sections, using Σm values from a monitor run (after flooding)

  6. Solid transport in mountain rivers: monitoring techniques and long term assessment as flood prevention tools

    Science.gov (United States)

    Longoni, Laura; Brambilla, Davide; Ivanov, Vladislav; Messa, Giacomo; Veronelli, Andrea; Radice, Alessio; Papini, Monica

    2017-04-01

    Floods are calamitous phenomena with an ever-increasing frequency around the globe, that often result in socio-economic damage and casualties. The role of the solid fraction in the river dynamic has been widely debated in the last decade and its importance is recognized as critical and not negligible in flood simulations as it has been evidenced that the severity of an event is often the result of the coupling of a flood wave with elevated solid transport rates. Nevertheless, assessing the quantity of sediment mobilized in a particular event is not feasible without a long term analysis of the river's dynamics and its morphological evolution since it is defined by past events. This work is focused on the techniques to improve knowledge about sediment production and transport through hydrological networks as a necessary component of a wise flood prevention planning. In particular, a multidisciplinary approach that combines hydraulic and geological knowledge is required in order to understand the evolution of the river sediment and how it will influence the following critical event. The methods are presented through a case study in Italy where a series of different approaches have been integrated to gain a comprehensive understanding of the problem: the sediment movement has been studied by a Eulerian as well as a Lagrangian approaches while hydraulic properties of the stream have been measured. The research started with an attempt to monitor sediment movements: in June 2016 300 sample pebbles, equipped with RFID (Radio Frequency IDentification) transponders, have been deployed in the river and tracked after every major rainfall event. The obtained data-set has been combined with a morphological analysis and a river flow discharge computed through PIV (Particle Image Velocimetry) method in order to identify the relation between a given rainfall event and sediment transport. Moreover, critical sediment size has been estimated from field data using three approaches: two

  7. Application of two quality indices as monitoring and management tools of rivers. Case study: the Imera Meridionale River, Italy.

    Science.gov (United States)

    Bonanno, Giuseppe; Lo Giudice, Rosa

    2010-04-01

    On the basis of the European Water Framework Directive (2000/60), the water resources of the member states of the European Community should reach good quality standards by 2015. Although such regulations illustrate the basic points for a comprehensive and effective policy of water monitoring and management, no practical tools are provided to face and solve the issues concerning freshwater ecosystems such as rivers. The Italian government has developed a set of regulations as adoption of the European Directive but failed to indicate feasible procedures for river monitoring and management. On a local scale, Sicilian authorities have implemented monitoring networks of watersheds, aiming at describing the general conditions of rivers. However, such monitoring programs have provided a relatively fragmentary picture of the ecological conditions of the rivers. In this study, the integrated use of environmental quality indices is proposed as a methodology able to provide a practical approach to river monitoring and management. As a case study, the Imera Meridionale River, Sicily's largest river, was chosen. The water quality index developed by the U.S. National Sanitation Foundation and the floristic quality index based on the Wilhelm method were applied. The former enabled us to describe the water quality according to a spatial-temporal gradient, whereas the latter focused on the ecological quality of riparian vegetation. This study proposes a holistic view of river ecosystems by considering biotic and abiotic factors in agreement with the current European regulations. How the combined use of such indices can guide sustainable management efforts is also discussed.

  8. The Application of State-of-the-Art Analytic Tools (Biosensors and Spectroscopy in Beverage and Food Fermentation Process Monitoring

    Directory of Open Access Journals (Sweden)

    Shaneel Chandra

    2017-09-01

    Full Text Available The production of several agricultural products and foods are linked with fermentation. Traditional methods used to control and monitor the quality of the products and processes are based on the use of simple chemical analysis. However, these methods are time-consuming and do not provide sufficient relevant information to guarantee the chemical changes during the process. Commonly used methods applied in the agriculture and food industries to monitor fermentation are those based on simple or single-point sensors, where only one parameter is measured (e.g., temperature or density. These sensors are used several times per day and are often the only source of data available from which the conditions and rate of fermentation are monitored. In the modern food industry, an ideal method to control and monitor the fermentation process should enable a direct, rapid, precise, and accurate determination of several target compounds, with minimal to no sample preparation or reagent consumption. Here, state-of-the-art advancements in both the application of sensors and analytical tools to monitor beverage and food fermentation processes will be discussed.

  9. A Novel Application for Low Frequency Electrochemical Impedance Spectroscopy as an Online Process Monitoring Tool for Viable Cell Concentrations

    Directory of Open Access Journals (Sweden)

    Christoph Slouka

    2016-11-01

    Full Text Available New approaches in process monitoring during industrial fermentations are not only limited to classical pH, dO2 and offgas analysis, but use different in situ and online sensors based on different physical principles to determine biomass, product quality, lysis and far more. One of the very important approaches is the in situ accessibility of viable cell concentration (VCC. This knowledge provides increased efficiency in monitoring and controlling strategies during cultivations. Electrochemical impedance spectroscopy—EIS—is used to monitor biomass in a fermentation of E. coli BL21(DE3, producing a recombinant protein using a fed batch-based approach. Increases in the double layer capacitance (Cdl, determined at frequencies below 1 kHz, are proportional to the increase of biomass in the batch and fed batch phase, monitored in offline and online modes for different cultivations. A good correlation of Cdl with cell density is found and in order to get an appropriate verification of this method, different state-of-the-art biomass measurements are performed and compared. Since measurements in this frequency range are largely determined by the double layer region between the electrode and media, rather minor interferences with process parameters (aeration, stirring are to be expected. It is shown that impedance spectroscopy at low frequencies is a powerful tool for cultivation monitoring.

  10. Evaluation of Florida physicians' knowledge and attitudes toward accessing the state prescription drug monitoring program as a prescribing tool.

    Science.gov (United States)

    Gershman, Jennifer A; Gershman, Jason A; Fass, Andrea D; Popovici, Ioana

    2014-12-01

    The purpose of this study is to assess Florida physicians' attitudes and knowledge toward accessing the state's prescription drug monitoring program (PDMP). Five thousand medical doctors and osteopathic physicians licensed in Florida were randomly selected for a voluntary and anonymous 15-question self-administered survey approved by the Institutional Review Board. Surveys were distributed through U.S. postal service mail. Likert-scale questions were used to assess prior knowledge (1 = none to 5 = excellent) and attitudes toward accessing the PDMP (1 = strongly disagree to 5 = strongly agree). The study yielded a response rate of 7.8%, 71.5% of whom agreed or strongly agreed that the PDMP is a useful tool. Among participants that have access and answered the PDMP usefulness question, 94.8% agree or strongly agree that it is a useful tool. There were 63 out of 64 physicians (98.4%) who conducted 25 or more searches who agreed or strongly agreed that the PDMP is a useful tool for monitoring patients' controlled substance histories. There were 72.5% of participants with access that answered the "doctor shopping" question who agreed that "doctor shopping" will decrease. Among the 64 most frequent PDMP users, 69.4% agreed or strongly agreed that they have prescribed fewer controlled substances after accessing the PDMP. The study revealed that a majority of participants believe that the PDMP is a useful tool for monitoring patients' controlled substance histories. More continuing education programs should be provided to Florida physicians to enhance their knowledge regarding PDMPs. Wiley Periodicals, Inc.

  11. Instruction Guide and Macro Analysis Tool for Community-led Air Monitoring

    Science.gov (United States)

    EPA has developed two tools for evaluating the performance of low-cost sensors and interpreting the data they collect to help citizen scientists, communities, and professionals interested in learning about local air quality.

  12. MURMoT: Design and Application of Microbial Uranium Reduction Monitoring Tools

    Energy Technology Data Exchange (ETDEWEB)

    Pennell, Kurt [Tufts Univ., Medford, MA (United States)

    2014-12-31

    The overarching project goal of the MURMoT project was the design of tools to elucidate the presence, abundance, dynamics, spatial distribution, and activity of metal- and radionuclide-transforming bacteria. To accomplish these objectives, an integrated approach that combined nucleic acid-based tools, proteomic workflows, uranium isotope measurements, and U(IV) speciation and structure analyses using the Advanced Photon Source (APS) at Argonne National Laboratory was developed.

  13. MURMoT: Design and Application of Microbial Uranium Reduction Monitoring Tools

    International Nuclear Information System (INIS)

    Pennell, Kurt

    2014-01-01

    The overarching project goal of the MURMoT project was the design of tools to elucidate the presence, abundance, dynamics, spatial distribution, and activity of metal- and radionuclide-transforming bacteria. To accomplish these objectives, an integrated approach that combined nucleic acid-based tools, proteomic workflows, uranium isotope measurements, and U(IV) speciation and structure analyses using the Advanced Photon Source (APS) at Argonne National Laboratory was developed.

  14. A review of the growth of monitoring and evaluation in South Africa: Monitoring and evaluation as a profession, an industry and a governance tool

    Directory of Open Access Journals (Sweden)

    Mark A. Abrahams

    2015-09-01

    Full Text Available South Africa is one several African countries with an official ministry responsible for monitoring and evaluation (M&E. Some of the other countries include Ghana, Kenya, Benin and Uganda. The development of M&E in South Africa has been stymied in part by its interdisciplinary nature, trying to find roots within historically a very discipline-based higher education system. Over the last ten years, however, there has been a huge increase in the number, scope and quality of evaluations conducted in this country. Government agencies and Non-government organisations (NGOs often using international donor funds for their own projects, have been engaged in outsourcing evaluation studies, and currently all government departments have established their own M&E units. There are statutory bodies such as the Public Service Commission (PSC and the Department for Planning, Monitoring and Evaluation (DPME with the responsibility to monitor and evaluate the government’s service delivery and performance. The South African Monitoring and Evaluation Association (SAMEA, established in 2005, draws together M&E practitioners, trainers in M&E, development agencies as well as government officials at its biennial conferences and sustains a vibrant community via its listserv – SAMEATalk. This article reviews the growth of monitoring and evaluation in South Africa and reflects on the current or prominent nature of M&E in this country. It deliberates about M&E developing into a profession, its growth as an industry or businessand its increasing adoption as a governance tool for development in South Africa. The paper concludes with some critical reflections on the growth of M&E in South Africa.

  15. Use of self-monitoring tools in a clinic sample of adults with type 2 diabetes.

    Science.gov (United States)

    Tanenbaum, Molly L; Bhatt, Harikrashna B; Thomas, Valerie A; Wing, Rena R

    2017-06-01

    Self-monitoring is an effective strategy for chronic disease management; many readily available mobile applications allow tracking of diabetes-related health behaviors but their use has not yet been integrated into routine clinical care. How patients engage with these applications in the real world is not well understood. The specific aim of this study is to survey adults with type 2 diabetes (T2D) regarding self-monitoring behaviors, including mobile application use. In 2015, we surveyed an adult diabetes clinic population (n = 96) regarding self-monitoring behaviors: diet, physical activity, weight, and blood glucose. Self-monitoring with any method ranged from 20-90 %. About half of the participants owned smartphones; few had mobile applications. The most common app-tracked behavior was physical activity, then weight and diet. Despite numerous available mobile health-tracking applications, few T2D adults from our sample used them, though many reported self-monitoring with other methods.

  16. Bioindicator plants as monitoring tools for urban and industrial pollutant sources - case studies from Austria

    Energy Technology Data Exchange (ETDEWEB)

    Soja, G.; Schafler, P.; Gerzabek, M. [Austrian Research Center Seibersdorf (Austria). Dept. of Environmental Research

    2002-07-01

    This paper presents two examples for the application of bioindicator techniques in environmental monitoring projects. The results presented here refer to the quantitation of the effects of environmental parameters on the behaviour of bioindicator plants. a.) Environmental monitoring of an industrial pollutant emitter in a rural environment. For monitoring the environmental impact of a coal-fired power plant, an extensive multi-annual monitoring programme had been established four years prior to the start of operation of the power plant. The programme included analyses of soils and field crops and the physiological responses of crop plants in non-filtered and carbon-filtered open-top chambers (OTC). b.) Monitoring of ozone effects on bioindicator plants in a large city and its rural environs. In a two-year multi-location study, the region of Vienna was analysed along a profile from the west to the southeast of the city for visual ozone injury of bioindicator plants. Meteorological conditions and air pollutant concentrations were recorded in detail at 9 out of 25 indicator stations. The resulting dataset was processed with multivariate techniques. (orig.)

  17. On-line sodium and cover as purity monitors gas operating tools at EBR-II

    International Nuclear Information System (INIS)

    Smith, C.R.F.; Richardson, W.J.; Holmes, J.T.

    1976-01-01

    Plugging temperature indicators, electrochemical oxygen meters and hydrogen diffusion meters are the on-line sodium purity monitors now in use at EBR-II. On-line gas chromatographs are used to monitor helium, hydrogen, oxygen and nitrogen impurities in the argon cover gases. Monitors for tritium-in-sodium and for hydrocarbons-in-cover gas have been developed and are scheduled for installation in the near future. An important advantage of on-line monitors over the conventional grab-sampling techniques is the speed of response to changing reactor conditions. This helps us to identify the source of the impurity, whether the cause may be transient or constant, and take corrective action as necessary. The oxygen meter is calibrated monthly against oxygen in sodium determined by the vanadium wire equilibration method. The other instruments either do not require calibration or are self-calibrating. The ranges, sensitivity and response times of all of the on-line purity monitors has proven satisfactory under EBR-II operating conditions

  18. Fiber‐optic distributed temperature sensing: A new tool for assessment and monitoring of hydrologic processes

    Science.gov (United States)

    Lane, John W.; Day-Lewis, Frederick D.; Johnson, Carole D.; Dawson, Cian B.; Nelms, David L.; Miller, Cheryl; Wheeler, Jerrod D.; Harvey, Charles F.; Karam, Hanan N.

    2008-01-01

    Fiber‐optic distributed temperature sensing (FO DTS) is an emerging technology for characterizing and monitoring a wide range of important earth processes. FO DTS utilizes laser light to measure temperature along the entire length of standard telecommunications optical fibers. The technology can measure temperature every meter over FO cables up to 30 kilometers (km) long. Commercially available systems can measure fiber temperature as often as 4 times per minute, with thermal precision ranging from 0.1 to 0.01 °C depending on measurement integration time. In 2006, the U.S. Geological Survey initiated a project to demonstrate and evaluate DTS as a technology to support hydrologic studies. This paper demonstrates the potential of the technology to assess and monitor hydrologic processes through case‐study examples of FO DTS monitoring of stream‐aquifer interaction on the Shenandoah River near Locke's Mill, Virginia, and on Fish Creek, near Jackson Hole, Wyoming, and estuary‐aquifer interaction on Waquoit Bay, Falmouth, Massachusetts. The ability to continuously observe temperature over large spatial scales with high spatial and temporal resolution provides a new opportunity to observe and monitor a wide range of hydrologic processes with application to other disciplines including hazards, climate‐change, and ecosystem monitoring.

  19. Framework and catalogue of tools for Participatory monitoring for Farmer Family Learning Groups and Marketing Associations

    DEFF Research Database (Denmark)

    Vaarst, Mette; Nalunga, Jane; Tibasiima, Thaddeo

    2016-01-01

    external facilitators of FFLGs, four FFLG officers from the four organisations in ECOSAF, 21 Marketing Association officers, and staff members and volunteers from NOGAMU, SATNET and Organic Denmark. In the process we have worked together from each our context, and exchanged ideas on farmer group...... of this project (2013-2015) was Farmer Family Learning Groups (FFLG) as a method for developing long-term food security through social capital building. Furthermore, another project based on the FFLG approach but focusing on the formation of Marketing Associations (MAs) contributed to this booklet. This project...... development, participation and monitoring. Participatory monitoring in Farmer Family Learning Groups and Marketing Associations is for the people and the groups who have set goals for themselves and need to monitor themselves whether they are getting closer to the goals which they have set. These groups...

  20. Implementation strategies and tools for condition based monitoring at nuclear power plants

    International Nuclear Information System (INIS)

    2007-05-01

    There is now an acute need to optimize maintenance to improve both reliability and competitiveness of nuclear power plant operation. There is an increasing tendency to move from the preventive (time based) maintenance concept to one dependent on plant and component conditions. In this context, various on-line and off-line condition monitoring and diagnostics, nondestructive inspection techniques and surveillance are used. Component selection for condition based maintenance, parameter selection for monitoring condition, evaluation of condition monitoring results are issues influencing the effectiveness of condition based maintenance. All these selections of components and parameters to be monitored, monitoring and diagnostics techniques to be used, acceptance criteria and trending for condition evaluation, and the economic aspect of predictive maintenance and condition monitoring should be incorporated into an integrated, effective condition based maintenance programme, which is part of the plant's overall maintenance optimization programme. This publication collects and analyses proven condition based maintenance strategies and techniques (engineering and organizational) in Member States. It includes selected papers on maintenance optimization presented during its preparation. This report was prepared under IAEA project on integrated NPP life cycle management including decommissioning. The main objective of an integrated life cycle management programme is to enable NPP's to compete, without compromising safety, successfully in the changing energy markets throughout their service life and to facilitate life extension and eventual decommissioning through improved engineering, technological, economic and managerial actions. The technical working group on NPP life management and other advisory groups nominated by the Member States provide recommendations on high priority needs of Member States in this area

  1. IDENTIFICATION AND MONITORING OF NOISE SOURCES OF CNC MACHINE TOOLS BY ACOUSTIC HOLOGRAPHY METHODS

    Directory of Open Access Journals (Sweden)

    Jerzy Józwik

    2016-06-01

    Full Text Available The paper presents the analysis of sound field emitted by selected CNC machine tools. The identification of noise sources and level was measured by acoustic holography for the 3-axis DMC 635eco machine tool and the 5-axis vertical machining centre DMU 65 monoBlock. The acoustic holography method allows precise identification and measurement of noise sources at different bandwidths of frequency. Detection of noise sources in tested objects allows diagnosis of their technical condition, as well as choice of effective means of noise reduction, which is highly significant from the perspective of minimising noise at the CNC machine operator workstation. Test results were presented as acoustic maps in various frequency ranges. Noise sources of the machine tool itself were identified, as well as the range of noise influence and the most frequent places of reflections and their span. The results of measurements were presented in figures and diagrams.

  2. A Business Analytics Software Tool for Monitoring and Predicting Radiology Throughput Performance.

    Science.gov (United States)

    Jones, Stephen; Cournane, Seán; Sheehy, Niall; Hederman, Lucy

    2016-12-01

    Business analytics (BA) is increasingly being utilised by radiology departments to analyse and present data. It encompasses statistical analysis, forecasting and predictive modelling and is used as an umbrella term for decision support and business intelligence systems. The primary aim of this study was to determine whether utilising BA technologies could contribute towards improved decision support and resource management within radiology departments. A set of information technology requirements were identified with key stakeholders, and a prototype BA software tool was designed, developed and implemented. A qualitative evaluation of the tool was carried out through a series of semi-structured interviews with key stakeholders. Feedback was collated, and emergent themes were identified. The results indicated that BA software applications can provide visibility of radiology performance data across all time horizons. The study demonstrated that the tool could potentially assist with improving operational efficiencies and management of radiology resources.

  3. Improving inflammatory arthritis management through tighter monitoring of patients and the use of innovative electronic tools

    NARCIS (Netherlands)

    Riel, P. van; Alten, R.; Combe, B.; Abdulganieva, D.; Bousquet, P.; Courtenay, M.; Curiale, C.; Gomez-Centeno, A.; Haugeberg, G.; Leeb, B.; Puolakka, K.; Ravelli, A.; Rintelen, B.; Sarzi-Puttini, P.

    2016-01-01

    Treating to target by monitoring disease activity and adjusting therapy to attain remission or low disease activity has been shown to lead to improved outcomes in chronic rheumatic diseases such as rheumatoid arthritis and spondyloarthritis. Patient-reported outcomes, used in conjunction with

  4. Shape selection in Landsat time series: A tool for monitoring forest dynamics

    Science.gov (United States)

    Gretchen G. Moisen; Mary C. Meyer; Todd A. Schroeder; Xiyue Liao; Karen G. Schleeweis; Elizabeth A. Freeman; Chris Toney

    2016-01-01

    We present a new methodology for fitting nonparametric shape-restricted regression splines to time series of Landsat imagery for the purpose of modeling, mapping, and monitoring annual forest disturbance dynamics over nearly three decades. For each pixel and spectral band or index of choice in temporal Landsat data, our method delivers a smoothed rendition of...

  5. Prism Foil from an LCD Monitor as a Tool for Teaching Introductory Optics

    Science.gov (United States)

    Planinsic, Gorazd; Gojkosek, Mihael

    2011-01-01

    Transparent prism foil is part of a backlight system in LCD monitors that are widely used today. This paper describes the optical properties of the prism foil and several pedagogical applications suitable for undergraduate introductory physics level. Examples include experiments that employ refraction, total internal reflection, diffraction and…

  6. The analysis of animal faeces as a tool to monitor antibiotic usage

    NARCIS (Netherlands)

    Berendsen, B.J.A.; Wegh, R.S.; Memelink, J.; Zuidema, T.; Stolker, A.A.M.

    2015-01-01

    The analysis of antibiotics in animal faeces is important to obtain more insight in the possible formation of bacterial resistance in the animals¿ gut, to learn about the dissemination of antibiotics to the environment, to monitor trends in antibiotic usage and to detect the illegal and off-label

  7. The NETLAKE Metadatabase – A tool to support automatic monitoring on lakes in Europe and beyond

    Czech Academy of Sciences Publication Activity Database

    Jennings, E.; de Eyto, E.; Laas, A.; Pierson, D. C.; Mircheva, G.; Naumoski, A.; Clarke, A.; Helay, M.; Šumberová, Kateřina; Langenhaun, D.

    2017-01-01

    Roč. 26, č. 4 (2017), s. 95-100 ISSN 1539-607X Grant - others:COST(XE) ES1201 Program:ES Institutional support: RVO:67985939 Keywords : sensor-based monitoring * data sharing * lakes and reservoirs Subject RIV: DA - Hydrology ; Limnology OBOR OECD: Marine biology, freshwater biology, limnology

  8. In vitro liver models are important tools to monitor the abuse of anabolic steroids in cattle

    NARCIS (Netherlands)

    Puymbroeck, M. van; Kuilman, M.E.M.; Maas, R.F.M.; Witkamp, R.F.; Leyssens, T.; Zande, D.J.M. van der; Gelan, J.; Raus, J.

    1998-01-01

    Current veterinary residue analysis mainly focuses on the monitoring of residues of the administered parent compound. However, it is possible that larger amounts of metabolites are excreted and that they can have a prolonged excretion period. In order to unravel specific metabolic steps and to

  9. Multivariate data analysis as a tool in advanced quality monitoring in the food production chain

    DEFF Research Database (Denmark)

    Bro, R.; van den Berg, F.; Thybo, A.

    2002-01-01

    This paper summarizes some recent advances in mathematical modeling of relevance in advanced quality monitoring in the food production chain. Using chemometrics-multivariate data analysis - it is illustrated how to tackle problems in food science more efficiently and, moreover, solve problems...

  10. Designing a Business Model for Environmental Monitoring Services Using Fast MCDS Innovation Support Tools

    Directory of Open Access Journals (Sweden)

    Tuomo Eskelinen

    2017-11-01

    Full Text Available The free availability of open data provides opportunities to start new businesses and gain business intelligence. However, although data is often used to support decisions and actions, the possibilities offered by modern sensor technologies with connections to cloud-based data collection services are not being effectively capitalized. Data collection systems are also not generally open source solutions, even though open and flexibly adjustable systems would broaden the opportunities for solutions and larger revenue streams. In this article, we used action research methods to discover new business opportunities in a semi-open information system that utilizes environmental monitoring data. We applied a four-stage innovation process for industry, which included context definition, idea generation, and selection, and produced multi-criteria decision support (MCDS data to help the design of business model. This was done to reveal business opportunities for an environmental monitoring service. Among these opportunities, one service-style business model canvas was identified as feasible and selected for further development. We identified items that are needed in the commercialization process of environmental monitoring services. Our process combines open environmental monitoring data, participative innovation process, and MCDS support, and it supports and accelerates a co-creative business model creation process that is cost-beneficial in terms of saving time. The results are applicable to the creation of an open data information system that supports data-driven innovation.

  11. Structural health monitoring (vibration) as a tool for identifying structural alterations of the lumbar spine

    DEFF Research Database (Denmark)

    Kawchuk, Gregory N; Hartvigsen, Jan; Edgecombe, Tiffany

    2016-01-01

    Structural health monitoring (SHM) is an engineering technique used to identify mechanical abnormalities not readily apparent through other means. Recently, SHM has been adapted for use in biological systems, but its invasive nature limits its clinical application. As such, the purpose...

  12. The Gypsy Moth Event Monitor for FVS: a tool for forest and pest managers

    Science.gov (United States)

    Kurt W. Gottschalk; Anthony W. Courter

    2007-01-01

    The Gypsy Moth Event Monitor is a program that simulates the effects of gypsy moth, Lymantria dispar (L.), within the confines of the Forest Vegetation Simulator (FVS). Individual stands are evaluated with a susceptibility index system to determine the vulnerability of the stand to the effects of gypsy moth. A gypsy moth outbreak is scheduled in the...

  13. Failure database and tools for wind turbine availability and reliability analyses. The application of reliability data for selected wind turbines

    DEFF Research Database (Denmark)

    Kozine, Igor; Christensen, P.; Winther-Jensen, M.

    2000-01-01

    The objective of this project was to develop and establish a database for collecting reliability and reliability-related data, for assessing the reliability of wind turbine components and subsystems and wind turbines as a whole, as well as for assessingwind turbine availability while ranking the ...... similar safety systems. The database was established with Microsoft Access DatabaseManagement System, the software for reliability and availability assessments was created with Visual Basic.......The objective of this project was to develop and establish a database for collecting reliability and reliability-related data, for assessing the reliability of wind turbine components and subsystems and wind turbines as a whole, as well as for assessingwind turbine availability while ranking...... the contributions at both the component and system levels. The project resulted in a software package combining a failure database with programs for predicting WTB availability and the reliability of all thecomponents and systems, especially the safety system. The report consists of a description of the theoretical...

  14. Reference chart of inspiratory muscle strength: a new tool to monitor the effect of pre-operative training.

    Science.gov (United States)

    van Buuren, S; Hulzebos, E H J; Valkenet, K; Lindeman, E; van Meeteren, N L U

    2014-06-01

    To develop a reference chart to monitor inspiratory muscle strength during pre-operative inspiratory muscle training for patients at high risk of developing postoperative pulmonary complications awaiting coronary artery bypass graft (CABG) surgery. Secondary data analysis using patients from the intervention arm of a randomised clinical trial. University medical centre. Patients at high risk of developing postoperative pulmonary complications awaiting CABG surgery. Patients performed inspiratory muscle training seven times per week for at least 2 weeks before surgery. Maximal inspiratory muscle strength. A new reference chart was produced using a non-linear time trend model with a normal error structure. The chart is a novel tool for monitoring the progress of inspiratory muscle training for physiotherapy practice. Wider use of this chart is recommended. Copyright © 2013 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  15. DoD-GEIS Rift Valley Fever Monitoring and Prediction System as a Tool for Defense and US Diplomacy

    Science.gov (United States)

    Anyamba, Assaf; Tucker, Compton J.; Linthicum, Kenneth J.; Witt, Clara J.; Gaydos, Joel C.; Russell, Kevin L.

    2011-01-01

    Over the last 10 years the Armed Forces Health Surveillance Center's Global Emerging Infections Surveillance and Response System (GEIS) partnering with NASA'S Goddard Space Flight Center and USDA's USDA-Center for Medical, Agricultural & Veterinary Entomology established and have operated the Rift Valley fever Monitoring and Prediction System to monitor, predict and assess the risk of Rift Valley fever outbreaks and other vector-borne diseases over Africa and the Middle East. This system is built on legacy DoD basic research conducted by Walter Reed Army Institute of Research overseas laboratory (US Army Medical Research Unit-Kenya) and the operational satellite environmental monitoring by NASA GSFC. Over the last 10 years of operation the system has predicted outbreaks of Rift Valley fever in the Horn of Africa, Sudan, South Africa and Mauritania. The ability to predict an outbreak several months before it occurs provides early warning to protect deployed forces, enhance public health in concerned countries and is a valuable tool use.d by the State Department in US Diplomacy. At the international level the system has been used by the Food and Agricultural Organization (FAD) and the World Health Organization (WHO) to support their monitoring, surveillance and response programs in the livestock sector and human health. This project is a successful testament of leveraging resources of different federal agencies to achieve objectives of force health protection, health and diplomacy.

  16. The six-sphere framework: A practical tool for assessing monitoring and evaluation systems

    Directory of Open Access Journals (Sweden)

    Kieron D. Crawley

    2017-04-01

    Conclusion: The article describes the framework in relation to other organisational development tools and gives some examples of how it can be used to make sense of the ECD environment. It highlights the potential of the framework to contribute to a more nuanced understanding of the ECD environment using a structured diagnostic approach and to move beyond conventional supply and demand models.

  17. Blood Glucose Monitoring as a Teaching Tool for Endocrinology: A New Perspective

    Science.gov (United States)

    Moats, Robert K., II

    2009-01-01

    The education of new allied health professionals and nurses in proper endocrine evaluation and care has become critical in recent years, especially considering the greatly increased prevalence of diabetes in adults and children. The evaluation of blood glucose levels in human volunteers over time is a powerful teaching tool for endocrinology that…

  18. Scorecard - An innovative simplified tool to supplement the existing monitoring mechanism to assess and improve performance of antiretroviral treatment centers

    Directory of Open Access Journals (Sweden)

    Sudhir Chawla

    2017-01-01

    Full Text Available Introduction: All 26 antiretroviral treatment (ART centers of Gujarat were monitored by Gujarat State AIDS Control Society under the National AIDS Control Program. A comprehensive tool is needed to identify gap in service delivery and to prioritize monitoring visits. Objectives: To supplement the existing monitoring system, identify strengths/weakness of ART centers, and give recommendations. Methodology: Scorecard was developed in spreadsheet format with 17 scoring indicators on monthly base from March 2014 onward. The centers were classified in three color zones: green (score ≥80%, yellow (score <80% and ≥50%, and red (score <50%. Visits were prioritized at centers with more indicators in yellow/red zone. The performance of centers was compared for March 2014 and March 2015. Results: The statistically significant improvement was observed in indicator “ART initiation within 2 months of eligibility,” while after removing red zone from analysis, four more indicators named “eligible patients transferred out before ART initiation, general clients started on ART, antenatal women started on ART, and pre-ART follow-up CD4 done” reflect statistically significant improvement. Quadrant analysis was done for some indicators, which provide insight that less number of eligible patients may be a reason for low initiation of ART at one center, and at four other centers, the possible reasons for low retention are high death rate and high lost to follow-up rate. Based on these findings, the recommendations were made to regular mentoring centers, improve coordination between ART center and care and support centers (CSCs, and conduct verbal autopsy. Conclusion: Scorecard is a simple and cost-effective tool for monitoring, and by highlighting low-performing indicators, it helps in improving quality of services provided at ART centers.

  19. TH-C-18A-08: A Management Tool for CT Dose Monitoring, Analysis, and Protocol Review

    International Nuclear Information System (INIS)

    Wang, J; Chan, F; Newman, B; Larson, D; Leung, A; Fleischmann, D; Molvin, L; Marsh, D; Zorich, C; Phillips, L

    2014-01-01

    Purpose: To develop a customizable tool for enterprise-wide managing of CT protocols and analyzing radiation dose information of CT exams for a variety of quality control applications Methods: All clinical CT protocols implemented on the 11 CT scanners at our institution were extracted in digital format. The original protocols had been preset by our CT management team. A commercial CT dose tracking software (DoseWatch,GE healthcare,WI) was used to collect exam information (exam date, patient age etc.), scanning parameters, and radiation doses for all CT exams. We developed a Matlab-based program (MathWorks,MA) with graphic user interface which allows to analyze the scanning protocols with the actual dose estimates, and compare the data to national (ACR,AAPM) and internal reference values for CT quality control. Results: The CT protocol review portion of our tool allows the user to look up the scanning and image reconstruction parameters of any protocol on any of the installed CT systems among about 120 protocols per scanner. In the dose analysis tool, dose information of all CT exams (from 05/2013 to 02/2014) was stratified on a protocol level, and within a protocol down to series level, i.e. each individual exposure event. This allows numerical and graphical review of dose information of any combination of scanner models, protocols and series. The key functions of the tool include: statistics of CTDI, DLP and SSDE, dose monitoring using user-set CTDI/DLP/SSDE thresholds, look-up of any CT exam dose data, and CT protocol review. Conclusion: our inhouse CT management tool provides radiologists, technologists and administration a first-hand near real-time enterprise-wide knowledge on CT dose levels of different exam types. Medical physicists use this tool to manage CT protocols, compare and optimize dose levels across different scanner models. It provides technologists feedback on CT scanning operation, and knowledge on important dose baselines and thresholds

  20. Aquatic indicator organisms as a tool to monitor discharges from nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Outola, Iisa; Vartti, Vesa-Pekka; Klemola, Seppo [STUK - Radiation and Nuclear Safety Authority, P.O. Box 14, 00881 Helsinki (Finland)

    2014-07-01

    There are four operating nuclear power plant units in Finland at two separate locations. The units started operation during 1977-1980. The surveillance of radioactive substances in the vicinities of the nuclear power plant is carried out under the permanent monitoring programs. Some 1000 samples are taken annually from the surroundings of the power plants to confirm that the discharges from the power plants are within permissible release limits and to monitor the dispersion of discharges in the environment. Aquatic indicator organisms (macro-algae, periphyton, mussels, crustacean, submerged aquatic plants) are included in the monitoring program. The indicator organisms are valuable monitoring objects both in normal and emergency situations because they accumulate effectively and often very rapidly radioactive substances from the medium. Six different species (Periphyton, Fucus vesiculosus, Myriophyllum spicatum, Potamogeton pectinatus, Saduria entomon, Macoma Baltica/Mytilus edulis) are collected regularly. Number of sampling location for each species varies from 1 to 7. Some species are collected continuously, some 1-2 times in a year. In this study we have evaluated the monitoring results for the aquatic indicator organisms for the period of 2005-2010 concerning concentration of discharge nuclides. Our aim was to answer the following questions using the monitoring data from aquatic organisms: 1) Which radionuclides are released to the marine environment and how often do we detect them? 2) How far from the nuclear power plants discharge radionuclides are detected? 3) How concentration of discharge radionuclides has changed with time in aquatic organisms? The number of discharge nuclides detected in the aquatic indicator samples was 11. Most of them were only detected in few samples, but {sup 58}Co, {sup 60}Co, {sup 54}Mn and {sup 110m}Ag were detected more frequently. Most of the observations above detection limits were made within the 5 km distance from the

  1. Monitoring Compliance to Promote Quality Assurance: Development of a Mental Health Clinical Chart Audit Tool in Belize, 2013.

    Science.gov (United States)

    Winer, Rachel A; Bennett, Eleanor; Murillo, Illouise; Schuetz-Mueller, Jan; Katz, Craig L

    2015-09-01

    Belize trained psychiatric nurse practitioners (PNPs) in the early 1990s to provide mental health services throughout the country. Despite overwhelming success, the program is limited by lack of monitoring, evaluation, and surveillance. To promote quality assurance, we developed a chart audit tool to monitor mental healthcare delivery compliance for initial psychiatric assessment notes completed by PNPs. After reviewing the Belize Health Information System electronic medical record system, we developed a clinical audit tool to capture 20 essential components for initial assessment clinical notes. The audit tool was then piloted for initial assessment notes completed during July through September of 2013. One hundred and thirty-four initial psychiatric interviews were audited. The average chart score among all PNPs was 9.57, ranging from 3 to 15. Twenty-three charts-or 17.2%-had a score of 14 or higher and met a 70% compliance benchmark goal. Among indicators most frequently omitted included labs ordered and named (15.7%) and psychiatric diagnosis (21.6%). Explicit statement of medications initiated with dose and frequency occurred in 47.0% of charts. Our findings provide direction for training and improvement, such as emphasizing the importance of naming labs ordered, medications and doses prescribed, and psychiatric diagnoses in initial assessment clinical notes. We hope this initial assessment helps enhance mental health delivery compliance by prompting creation of BHIS templates, development of audits tools for revisit follow-up visits, and establishment of corrective actions for low-scoring practitioners. These efforts may serve as a model for implementing quality assurance programming in other low resource settings.

  2. Regulated bioluminescence as a tool for bioremediation process monitoring and control of bacterial cultures

    Science.gov (United States)

    Burlage, Robert S.; Heitzer, Armin; Digrazia, Philip M.

    1991-01-01

    An effective on-line monitoring technique for toxic waste bioremediation using bioluminescent microorganisms has shown great potential for the description and optimization of biological processes. The lux genes of the bacterium Vibrio fischeri are used by this species to produce visible light. The lux genes can be genetically fused to the control region of a catabolic gene, with the result that bioluminescence is produced whenever the catabolic gene is induced. Thus the detection of light from a sample indicates that genetic expression from a specific gene is occurring. This technique was used to monitor biodegradation of specific contaminants from waste sites. For these studies, fusions between the lux genes and the operons for naphthalene and toluene/xylene degradation were constructed. Strains carrying one of these fusions respond sensitively and specifically to target substrates. Bioluminescence from these cultures can be rapidly measured in a nondestructive and noninvasive manner. The potential for this technique in this and other biological systems is discussed.

  3. Microalgal process-monitoring based on high-selectivity spectroscopy tools: status and future perspectives

    DEFF Research Database (Denmark)

    Podevin, Michael Paul Ambrose; Fotidis, Ioannis; Angelidaki, Irini

    2017-01-01

    -value chemicals in a biorefinery concept. On-line and in-line monitoring of macromolecules such as lipids, proteins, carbohydrates, and high-value pigments will be more critical to maintain product quality and consistency for downstream processing in a biorefinery to maintain and valorize these markets. The main......Microalgae are well known for their ability to accumulate lipids intracellularly, which can be used for biofuels and mitigate CO2 emissions. However, due to economic challenges, microalgae bioprocesses have maneuvered towards the simultaneous production of food, feed, fuel, and various high...... contribution of this review is to present current and prospective advances of on-line and in-line process analytical technology (PAT), with high-selectivity – the capability of monitoring several analytes simultaneously – in the interest of improving product quality, productivity, and process automation...

  4. Structural health monitoring tools for late and end of life management of offshore wind turbines

    DEFF Research Database (Denmark)

    McGugan, Malcolm; McKirdy, Scott

    2016-01-01

    optimisation and service condition monitoring. However, as with other structures, in time the issues of "wear and tear" and remaining life assessment become increasingly prevalent. The dynamics of operating an offshore wind farm varies considerably from existing oil & gas structures. With lower operating...... margins and the predominance of low redundancy structures, accurate structural health monitoring can play a strong role in safe management and enable increased operating time at end of life and decommissioning. Late life operations of offshore wind farms can pose significant challenges, balancing......The late and end of life stages in an offshore wind turbines (OWT) life cycle have unique features that must be considered. The initial focus on risks associated with start-up issues due to design, manufacturing or process elements gives way to a stable period of operation and maintenance...

  5. Oracle as a tool for monitoring data management in French nuclear power plants

    International Nuclear Information System (INIS)

    Joussellin, A.; Tarteret, P.; Gal, A.

    1996-05-01

    On-line monitoring of the main components of the French nuclear power plants is performed using an integrated system called PSAD (Poste de Surveillance et d'Aide au Diagnostic). In real-time, physical measurement data are continuously acquired, computed and stored in an ORACLE database. All measurement data are dated and represent a wide range of physical variables (temperatures, vibrations, acoustic waves,...). Then, millions of measurements are available to the operator for diagnostic. (author)

  6. LYSIMETER - A UNIQUE TOOL FOR MONITORING THE INTERACTIONS AMONG THE COMPONENTS OF ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Ivan Matušek

    2016-06-01

    Full Text Available Modern lysimeter facilities in connection with meteorological stations allow monitoring and evaluation of mutual basic components of the environment, such as water, air, soil and vegetation. Water is the most important component of the ecosystem and the component which connects all the other components. Therefore, we need to know the basic distribution and water balance in the different components of the environment to be able to interpret some processes in nature. Rainfall, which is the primary source of vital processes in the soil, is formed in the air. The amount of precipitation that gets into the soil and into the groundwater is affected by weather conditions. Primary distribution of rainwater is divided between infiltration, surface runoff, transpiration and evapotranspiration. The amount of water infiltrated into the soil and then evaporated by solar activity or activities of plants can be identified primarily by monitoring changes in weight. For this monitoring we use weighable lysimeter. This equipment with the monolith size of surface area 1 m2 and the depth of 1.5 m is able to follow online updates of weight of the 2 ton body with an accuracy of 100 g. When we add to quantification of leakages through the bottom layer, we obtain a comprehensive record of rainfall at the time in the natural environment of the individual components. The obtained data can be further interpreted in terms of the needs of hydrology, agriculture, and environmental studies, and according to the purpose and objectives for which we want to use them.

  7. HappyFace as a monitoring tool for the ATLAS experiment

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00367045; Yahyapour, Ramin

    The importance of monitoring on HEP grid computing systems is growing due to a significant increase in their complexity. Computer scientists and administrators have been studying and building effective ways to gather information on and clarify a status of each local grid infrastructure. The HappyFace project aims at making the above-mentioned workflow possible. It aggregates, processes and stores the informa- tion and the status of different HEP monitoring resources into the common database of HappyFace. The system displays the information and the status through a single interface. However, this model of HappyFace relied on the monitoring resources which are al- ways under development in the HEP experiments. Consequently, HappyFace needed to have direct access methods to the grid application and grid service layers in the dif- ferent HEP grid systems. To cope with this issue, we use a reliable HEP software repos- itory, the CernVM File System. We propose a new implementation and an architecture of HappyFace, ...

  8. Ultramicroelectrode Array Based Sensors: A Promising Analytical Tool for Environmental Monitoring

    OpenAIRE

    Orozco, Jahir; Fern?ndez-S?nchez, C?sar; Jim?nez-Jorquera, Cecilia

    2010-01-01

    The particular analytical performance of ultramicroelectrode arrays (UMEAs) has attracted a high interest by the research community and has led to the development of a variety of electroanalytical applications. UMEA-based approaches have demonstrated to be powerful, simple, rapid and cost-effective analytical tools for environmental analysis compared to available conventional electrodes and standardised analytical techniques. An overview of the fabrication processes of UMEAs, their characteri...

  9. Optical Method For Monitoring Tool Control For Green Burnishing With Using Of Algorithms With Adaptive Settings

    Science.gov (United States)

    Lukyanov, A. A.; Grigoriev, S. N.; Bobrovskij, I. N.; Melnikov, P. A.; Bobrovskij, N. M.

    2017-05-01

    With regard to the complexity of the new technology and increase its reliability requirements laboriousness of control operations in industrial quality control systems increases significantly. The importance of quality management control due to the fact that its promotes the correct use of production conditions, the relevant requirements are required. Digital image processing allows to reach a new technological level of production (new technological way). The most complicated automated interpretation of information is the basis for decision-making in the management of production processes. In the case of surface analysis of tools used for processing with the using of metalworking fluids (MWF) it is more complicated. The authors suggest new algorithm for optical inspection of the wear of the cylinder tool for burnishing, which used in surface plastic deformation without using of MWF. The main advantage of proposed algorithm is the possibility of automatic recognition of images of burnisher tool with the subsequent allocation of its boundaries, finding a working surface and automatically allocating the defects and wear area. Software that implements the algorithm was developed by the authors in Matlab programming environment, but can be implemented using other programming languages.

  10. DNAqua-Net: Developing new genetic tools for bioassessment and monitoring of aquatic ecosystems in Europe

    Directory of Open Access Journals (Sweden)

    Florian Leese

    2016-11-01

    Full Text Available The protection, preservation and restoration of aquatic ecosystems and their functions are of global importance. For European states it became legally binding mainly through the EU-Water Framework Directive (WFD. In order to assess the ecological status of a given water body, aquatic biodiversity data are obtained and compared to a reference water body. The quantified mismatch obtained determines the extent of potential management actions. The current approach to biodiversity assessment is based on morpho-taxonomy. This approach has many drawbacks such as being time consuming, limited in temporal and spatial resolution, and error-prone due to the varying individual taxonomic expertise of the analysts. Novel genomic tools can overcome many of the aforementioned problems and could complement or even replace traditional bioassessment. Yet, a plethora of approaches are independently developed in different institutions, thereby hampering any concerted routine application. The goal of this Action is to nucleate a group of researchers across disciplines with the task to identify gold-standard genomic tools and novel eco-genomic indices for routine application in biodiversity assessments of European fresh- and marine water bodies. Furthermore, DNAqua-Net will provide a platform for training of the next generation of European researchers preparing them for the new technologies. Jointly with water managers, politicians, and other stakeholders, the group will develop a conceptual framework for the standard application of eco-genomic tools as part of legally binding assessments.

  11. New Electric Online Oil Condition Monitoring Sensor – an Innovation in Early Failure Detection of Industrial Gears

    Directory of Open Access Journals (Sweden)

    Manfred Mauntz

    2013-02-01

    Full Text Available A new online diagnostics system for the continuous condition monitoring of lubricating oils in industrial gearboxes is presented. Characteristic features of emerging component damage, such as wear, contamination or chemical aging, are identified in an early stage. The OilQSens® sensor effectively controls the proper operation conditions of bearings and cogwheels in gears. Also, the condition of insulating oils in transformers can be monitored. The online diagnostics system measures components of the specific complex impedance of oils. For instance, metal abrasion due to wear debris, broken oil molecules, forming acids or oil soaps result in an increase of the electrical conductivity, which directly correlates with the degree of contamination in the oil. The dielectrical properties of the oils are particularly determined by the water content that becomes accessible via an additional accurate measurement of the dielectric constant. For additivated oils, statements on the degradation of additives can also be derived from changes in the dielectric constant. For an efficient machine utilization and targeted damage prevention, the new OilQSens® online condition monitoring sensor system allows for timely preventative maintenance on demand rather than in rigid inspection intervals. The determination of impurities or reduction in the quality of the oil and the quasi continuous evaluation of wear and chemical aging follow the holistic approach of a real-time monitoring of a change in the condition of the oil-machine system. Once the oil condition monitoring sensors are installed on the plants, the measuring data can be displayed and evaluated elsewhere. The measuring signals are transmitted to a web-based condition monitoring system via LAN, WLAN or serial interfaces of the sensor system. Monitoring of the damage mechanisms during proper operation below the tolerance limits of the components enables specific preventive maintenance independent of rigid

  12. Application of Two Quality Indices as Monitoring and Management Tools of Rivers. Case Study: The Imera Meridionale River, Italy

    Science.gov (United States)

    Bonanno, Giuseppe; Giudice, Rosa Lo

    2010-04-01

    On the basis of the European Water Framework Directive (2000/60), the water resources of the member states of the European Community should reach good quality standards by 2015. Although such regulations illustrate the basic points for a comprehensive and effective policy of water monitoring and management, no practical tools are provided to face and solve the issues concerning freshwater ecosystems such as rivers. The Italian government has developed a set of regulations as adoption of the European Directive but failed to indicate feasible procedures for river monitoring and management. On a local scale, Sicilian authorities have implemented monitoring networks of watersheds, aiming at describing the general conditions of rivers. However, such monitoring programs have provided a relatively fragmentary picture of the ecological conditions of the rivers. In this study, the integrated use of environmental quality indices is proposed as a methodology able to provide a practical approach to river monitoring and management. As a case study, the Imera Meridionale River, Sicily’s largest river, was chosen. The water quality index developed by the U.S. National Sanitation Foundation and the floristic quality index based on the Wilhelm method were applied. The former enabled us to describe the water quality according to a spatial-temporal gradient, whereas the latter focused on the ecological quality of riparian vegetation. This study proposes a holistic view of river ecosystems by considering biotic and abiotic factors in agreement with the current European regulations. How the combined use of such indices can guide sustainable management efforts is also discussed.

  13. Italian monitoring registries: a tool for a safer use of innovative drugs? Data from the national pharmacovigilance system.

    Science.gov (United States)

    Magro, Lara; Arzenton, Elena; Moretti, Ugo; Sottosanti, Laura; Potenza, Simona; Leone, Roberto

    2016-12-01

    Our aim was to investigate the ADR reports of drugs with a monitoring registry (MR drugs), in particular those related to abuse/misuse, medication error, overdose, which might indicate an unsafe use. We compared these reports with those of similar drugs without a registry (non-MR drugs), thus verifying whether the registries could be useful tools for a safer use of innovative drugs. All ADR reports included in the Italian Pharmacovigilance Network database from January 1 st 2013 to December 31 st 2015 (vaccines and literature cases excluded) were analysed. We compared the ADR reports of MR and non-MR drugs with the same ATC class at III level. The percentage of ADR reports with a completed 'Section 7' was significantly lower for MR compared to non-MR drugs (2.0 versus 6.2, p < 0.001). The difference concerned in particular the ADR reports related to abuse/misuse, medication errors and overdose. These reports, more strictly related to inappropriate use, were less frequent for MR drugs in all the considered ATC classes. Our study suggests that monitoring registries could be a useful tool for the reduction of frequency of ADRs related to inappropriate use, besides the control of pharmaceutical budget.

  14. Focused beam reflectance method as an innovative (PAT) tool to monitor in-line granulation process in fluidized bed.

    Science.gov (United States)

    Alshihabi, Firas; Vandamme, Thierry; Betz, Gabriele

    2013-02-01

    Fluidized bed granulation is a commonly used unit operation in the pharmaceutical industry. But still to obtain and control the desired granule size is challenging due to many process variables affecting the final product. Focused beam reflectance measurement (FBRM, Mettler-Toledo, Switzerland) is an increasingly popular particle growth analysis technique. FBRM tool was installed in two different locations inside a fluidized bed granulator (GPCG2, Glatt, Binzen) in order to monitor the granulation growth kinetics. An experimental design was created to study the effect of process variables using FBRM probe and comparing the results with the one's measured by sieve analysis. The probe location is of major importance to get smooth and robust curves. The excess feeding of binder solution might lead to agglomeration and thus to process collapse, however this phenomenon was clearly detected with FBRM method. On the other hand, the process variables at certain levels might affect the FBRM efficiency by blocking the probe window with sticky particles. A good correlation was obtained (R(2) = 0.95) between FBRM and sieve analysis mean particle size. The proposed in-line monitoring tool enables the operator to select appropriate process parameters and control the wet granulation process more efficiently.

  15. Veno-occlusive disease nurse management: development of a dynamic monitoring tool by the GITMO nursing group.

    Science.gov (United States)

    Botti, Stefano; Orlando, Laura; Gargiulo, Gianpaolo; Cecco, Valentina De; Banfi, Marina; Duranti, Lorenzo; Samarani, Emanuela; Netti, Maria Giovanna; Deiana, Marco; Galuppini, Vera; Pignatelli, Adriana Concetta; Ceresoli, Rosanna; Vedovetto, Alessio; Rostagno, Elena; Bambaci, Marilena; Dellaversana, Cristina; Luminari, Stefano; Bonifazi, Francesca

    2016-01-01

    Veno-occlusive disease (VOD) is a complication arising from the toxicity of conditioning regimens that have a significant impact on the survival of patients who undergo stem cell transplantation. There are several known risk factors for developing VOD and their assessment before the start of conditioning regimens could improve the quality of care. Equally important are early identification of signs and symptoms ascribable to VOD, rapid diagnosis, and timely adjustment of support therapy and treatment. Nurses have a fundamental role at the stages of assessment and monitoring for signs and symptoms; therefore, they should have documented skills and training. The literature defines nurses' areas of competence in managing VOD, but in the actual clinical practice, this is not so clear. Moreover, there is an intrinsic difficulty in managing VOD due to its rapid and often dramatic evolution, together with a lack of care tools to guide nurses. Through a complex evidence-based process, the Gruppo Italiano per il Trapianto di Midollo Osseo (GITMO), cellule staminali emopoietiche e terapia cellulare nursing board has developed an operational flowchart and a dynamic monitoring tool applicable to haematopoietic stem cell transplantation patients, whether they develop this complication or not.

  16. CRIT-LINE: a noninvasive tool to monitor hemoglobin levels in pediatric hemodialysis patients.

    Science.gov (United States)

    Garro, Rouba; Sutherland, Scott; Bayes, Liz; Alexander, Steven; Wong, Cynthia

    2015-06-01

    The national average for achieving the KDOQI-recommended hemoglobin (Hgb) target level of 11-12 g/dL is low with the current anemia management protocol of measuring Hgb levels every 2-4 weeks to guide intervention. The objective of this study was to correlate initial Hgb readings from the CRIT-LINE monitor with actual serum Hgb levels in pediatric patients on hemodialysis (HD). Data were collected from pediatric HD patients who had Hgb tests ordered for routine and/or clinical reasons. Hgb concentrations were read with the CRIT-LINE after 0.5 or 1 L of blood had been processed by HD in patients with a body weight of ≤20 or >20 kg, respectively. Ultrafiltration was kept at a minimum until the CRIT-LINE Hgb was read. In total, 217 Hgb readings from 23 HD patients were analyzed. Results showed a statistically significant correlation between CRIT-LINE readings and laboratory Hgb measurements (r = 0.94, p < 0.0001) using Pearson correlation coefficients for well-distributed data. The mean Hgb levels measured by CRIT-LINE and the laboratory were 11.12 ± 1.63 and 11.31 ± 1.69 g/dL, respectively. The CRIT-LINE monitor is an accurate instrument for monitoring Hgb levels in HD patients. Further studies will be needed to evaluate whether using CRIT-LINE Hgb levels to guide anemia management will improve the percentage of children with Hgb levels within target.

  17. A Novel Chronic Opioid Monitoring Tool to Assess Prescription Drug Steady State Levels in Oral Fluid.

    Science.gov (United States)

    Shaparin, Naum; Mehta, Neel; Kunkel, Frank; Stripp, Richard; Borg, Damon; Kolb, Elizabeth

    2017-11-01

    Interpretation limitations of urine drug testing and the invasiveness of blood toxicology have motivated the desire for the development of simpler methods to assess biologically active drug levels on an individualized patient basis. Oral fluid is a matrix well-suited for the challenge because collections are based on simple noninvasive procedures and drug concentrations better correlate to blood drug levels as oral fluid is a filtrate of the blood. Well-established pharmacokinetic models were utilized to generate oral fluid steady state concentration ranges to assess the interpretive value of the alternative matrix to monitor steady state plasma oxycodone levels. Paired oral fluid and plasma samples were collected from patients chronically prescribed oxycodone and quantitatively analyzed by liquid chromatography tandem mass spectrometry. Steady state plasma concentration ranges were calculated for each donor and converted to an equivalent range in oral fluid. Measured plasma and oral fluid oxycodone concentrations were compared with respective matrix-matched steady state ranges, using each plasma steady state classification as the control. A high degree of correlation was observed between matrices when classifying donors according to expected steady state oxycodone concentration. Agreement between plasma and oral fluid steady state classifications was observed in 75.6% of paired samples. This study supports novel application of basic pharmacokinetic knowledge to the pain management industry, simplifying and improving individualized drug monitoring and risk assessment through the use of oral fluid drug testing. Many benefits of established therapeutic drug monitoring in plasma can be realized in oral fluid for patients chronically prescribed oxycodone at steady state. © 2017 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  18. Brainstem auditory evoked potential monitoring and neuro-endoscopy: Two tools to ensure hearing preservation and surgical success during microvascular decompression

    Directory of Open Access Journals (Sweden)

    Cheng-Chia Lee

    2014-06-01

    Conclusion: The results of this retrospective study emphasized the importance of BAEP monitoring and neuro-endoscopy during MVD. It is well known that BAEP monitoring can preserve hearing function, and the endoscope offers neurosurgeons a second look to identify the nerve root entry zone and confirms the position of the Teflon felt. These two tools are especially useful in difficult cases.

  19. Comparison of Raman, NIR, and ATR FTIR spectroscopy as analytical tools for in-line monitoring of CO2 concentration in an amine gas treating process

    NARCIS (Netherlands)

    Kachko, A.; Ham, L.V. van der; Bardow, A.; Vlugt, T.J.H.; Goetheer, E.L.V.

    2016-01-01

    Chemical absorption of CO2 using aqueous amine-based solvents is one of the common approaches to control acidic gases emissions to the atmosphere. Improvement in the efficiency of industrial processes requires precise monitoring tools that fit with the specific application. Process monitoring using

  20. Methods and tools for students' health indicators computer evaluation and monitoring

    International Nuclear Information System (INIS)

    Finagin, V.G.

    2011-01-01

    Architecture, structure, interfaces and functional tasks of the computer monitoring the health of students have been defined in this work. A pattern of a graphical representation of a set of health indicators in the form of a radar chart with the designation of criteria of indicator's norms allowing the professionals to make a comprehensive medical report on the state of health of the student have been proposed. A pattern of a graphical representation of the results of the correlation analysis, which allows the expert to make a medical report on a causal relationship between the set of health indicators, have been also proposed [ru

  1. Are trophic and diversity indices based on macrophyte communities pertinent tools to monitor water quality?

    Science.gov (United States)

    Thiebaut, Gabrielle; Guérold, François; Muller, Serge

    2002-08-01

    Diversity and trophic indices based on macrophyte communities were calculated to test their pertinence to monitoring water quality in the Northern Vosges (NE of France). Highly significant correlations were found between the four tested chemical variables (bicarbonate, calcium, phosphorus and ammonium nitrogen) and trophic indices and between them and abundance and richness. Trophic indices and McIntosh's index appeared to be more effective in predicting water quality than diversity indices. Diversity indices do not necessarily provide any direct information on the quality or degree of degradation of the environment from which the sample was taken, whereas trophic indices do.

  2. Verification of organ doses calculated by a dose monitoring software tool based on Monte Carlo Simulation in thoracic CT protocols.

    Science.gov (United States)

    Guberina, Nika; Suntharalingam, Saravanabavaan; Naßenstein, Kai; Forsting, Michael; Theysohn, Jens; Wetter, Axel; Ringelstein, Adrian

    2018-03-01

    Background The importance of monitoring of the radiation dose received by the human body during computed tomography (CT) examinations is not negligible. Several dose-monitoring software tools emerged in order to monitor and control dose distribution during CT examinations. Some software tools incorporate Monte Carlo Simulation (MCS) and allow calculation of effective dose and organ dose apart from standard dose descriptors. Purpose To verify the results of a dose-monitoring software tool based on MCS in assessment of effective and organ doses in thoracic CT protocols. Material and Methods Phantom measurements were performed with thermoluminescent dosimeters (TLD LiF:Mg,Ti) using two different thoracic CT protocols of the clinical routine: (I) standard CT thorax (CTT); and (II) CTT with high-pitch mode, P = 3.2. Radiation doses estimated with MCS and measured with TLDs were compared. Results Inter-modality comparison showed an excellent correlation between MCS-simulated and TLD-measured doses ((I) after localizer correction r = 0.81; (II) r = 0.87). The following effective and organ doses were determined: (I) (a) effective dose = MCS 1.2 mSv, TLD 1.3 mSv; (b) thyroid gland = MCS 2.8 mGy, TLD 2.5 mGy; (c) thymus = MCS 3.1 mGy, TLD 2.5 mGy; (d) bone marrow = MCS 0.8 mGy, TLD 0.9 mGy; (e) breast = MCS 2.5 mGy, TLD 2.2 mGy; (f) lung = MCS 2.8 mGy, TLD 2.7 mGy; (II) (a) effective dose = MCS 0.6 mSv, TLD 0.7 mSv; (b) thyroid gland = MCS 1.4 mGy, TLD 1.8 mGy; (c) thymus = MCS 1.4 mGy, TLD 1.8 mGy; (d) bone marrow = MCS 0.4 mGy, TLD 0.5 mGy; (e) breast = MCS 1.1 mGy, TLD 1.1 mGy; (f) lung = MCS 1.2 mGy, TLD 1.3 mGy. Conclusion Overall, in thoracic CT protocols, organ doses simulated by the dose-monitoring software tool were coherent to those measured by TLDs. Despite some challenges, the dose-monitoring software was capable of an accurate dose calculation.

  3. The TrialsTracker: Automated ongoing monitoring of failure to share clinical trial results by all major companies and research institutions.

    Science.gov (United States)

    Powell-Smith, Anna; Goldacre, Ben

    2016-01-01

    Background : Failure to publish trial results is a prevalent ethical breach with a negative impact on patient care. Audit is an important tool for quality improvement. We set out to produce an online resource that automatically identifies the sponsors with the best and worst record for failing to share trial results. Methods: A tool was produced that identifies all completed trials from clinicaltrials.gov, searches for results in the clinicaltrials.gov registry and on PubMed, and presents summary statistics for each sponsor online. Results : The TrialsTracker tool is now available. Results are consistent with previous publication bias cohort studies using manual searches. The prevalence of missing studies is presented for various classes of sponsor. All code and data is shared. Discussion: We have designed, built, and launched an easily accessible online service, the TrialsTracker, that identifies sponsors who have failed in their duty to make results of clinical trials available, and which can be maintained at low cost. Sponsors who wish to improve their performance metrics in this tool can do so by publishing the results of their trials.

  4. Ultramicroelectrode Array Based Sensors: A Promising Analytical Tool for Environmental Monitoring

    Directory of Open Access Journals (Sweden)

    Cecilia Jiménez-Jorquera

    2010-01-01

    Full Text Available The particular analytical performance of ultramicroelectrode arrays (UMEAs has attracted a high interest by the research community and has led to the development of a variety of electroanalytical applications. UMEA-based approaches have demonstrated to be powerful, simple, rapid and cost-effective analytical tools for environmental analysis compared to available conventional electrodes and standardised analytical techniques. An overview of the fabrication processes of UMEAs, their characterization and applications carried out by the Spanish scientific community is presented. A brief explanation of theoretical aspects that highlight their electrochemical behavior is also given. Finally, the applications of this transducer platform in the environmental field are discussed.

  5. Ultramicroelectrode array based sensors: a promising analytical tool for environmental monitoring.

    Science.gov (United States)

    Orozco, Jahir; Fernández-Sánchez, César; Jiménez-Jorquera, Cecilia

    2010-01-01

    The particular analytical performance of ultramicroelectrode arrays (UMEAs) has attracted a high interest by the research community and has led to the development of a variety of electroanalytical applications. UMEA-based approaches have demonstrated to be powerful, simple, rapid and cost-effective analytical tools for environmental analysis compared to available conventional electrodes and standardised analytical techniques. An overview of the fabrication processes of UMEAs, their characterization and applications carried out by the Spanish scientific community is presented. A brief explanation of theoretical aspects that highlight their electrochemical behavior is also given. Finally, the applications of this transducer platform in the environmental field are discussed.

  6. Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis.

    Science.gov (United States)

    Ciulli, A; Abell, C

    2005-08-01

    Knowledge of biomolecular interactions is of importance to our understanding of biological processes such as enzyme catalysis and inhibition. Biophysical techniques enable sensitive detection and accurate characterization of binding and are therefore powerful tools in enzymology and rational drug design. The applications of NMR spectroscopy and isothermal titration calorimetry to study enzyme-ligand interactions will be discussed. Recent work on ketopantoate reductase, which catalyses an important step on the biosynthetic pathway to vitamin B5, is used to illustrate the potential of this approach.

  7. Tools for Texts Monitoring and Analysis Aimed at the Field of Social Disasters, Catastrophes, and Terrorism

    Directory of Open Access Journals (Sweden)

    Svetlana Cojocaru

    2016-08-01

    Full Text Available Throughout its life mankind faces various disasters and catastrophes: natural, technogenic, social. One of the important sources of information for these situations is the huge volume of unstructured data available in the global information networks. In this study, we describe a tool set that includes methods for extracting relevant texts from the networks, their classification and analysis. Two stages are described: preparatory and processing. The first one deals with patterns (texts and keywords creation, during the second phase news texts are processed using database and controlled vocabulary.

  8. The ACB technique: a biomagentic tool for monitoring gastrointestinal contraction directly from smooth muscle in dogs

    International Nuclear Information System (INIS)

    Américo, Madileine F; Andreis, Uilian; Miranda, José Ricardo A; Oliveira, Ricardo B; Corá, Luciana A; Marques, Rozemeire G; Romeiro, Fernando G

    2010-01-01

    The aim of this paper was to verify whether AC biosusceptometry (ACB) is suitable for monitoring gastrointestinal (GI) contraction directly from smooth muscle in dogs, comparing with electrical recordings simultaneously. All experiments were performed in dogs with magnetic markers implanted under the serosa of the right colon and distal stomach, and their movements were recorded by ACB. Monopolar electrodes were implanted close to the magnetic markers and their electric potentials were recorded by electromyography (EMG). The effects of neostigmine, hyoscine butylbromide and meal on gastric and colonic parameters were studied. The ACB signal from the distal stomach was very similar to EMG; in the colonic recordings, however, within the same low-frequency band, ACB and EMG signals were characterized by simultaneity or a widely changeable frequency profile with time. ACB recordings were capable of demonstrating the changes in gastric and colonic motility determined by pharmacological interventions as well as by feeding. Our results reinforce the importance of evaluating the mechanical and electrical components of motility and show a temporal association between them. ACB and EMG are complementary for studying motility, with special emphasis on the colon. ACB offers an accurate method for monitoring in vivo GI motility

  9. The analysis of animal faeces as a tool to monitor antibiotic usage.

    Science.gov (United States)

    Berendsen, Bjorn J A; Wegh, Robin S; Memelink, Joost; Zuidema, Tina; Stolker, Linda A M

    2015-01-01

    The analysis of antibiotics in animal faeces is important to obtain more insight in the possible formation of bacterial resistance in the animals׳ gut, to learn about the dissemination of antibiotics to the environment, to monitor trends in antibiotic usage and to detect the illegal and off-label use of antibiotics. To facilitate these studies a comprehensive method for the analysis of trace levels of 44 antibiotic compounds including tetracyclines, quinolones, macrolides and sulfonamides in animal faeces by liquid chromatography in combination with tandem mass spectrometric (LC-MS/MS) detection is reported. The method is fully validated according to European regulation and showed satisfactory quantitative performance according to the stringent criteria adopted, with the exception of some of the macrolide compounds, which can be analysed with somewhat high measurement uncertainty. A large survey was carried out monitoring swine and cattle faeces and the outcomes were striking. In 55% of the swines, originating from 80% of the swine farms and in 75% of the calves, originating from 95% of the cattle farms, antibiotics were detected. Oxytetracycline, doxycycline and sulfadiazine were the most detected antibiotics, followed by tetracycline, flumequine, lincomycin and tylosin. Over 34% of the faeces samples contained two or more different antibiotics with a maximum of eight. Possible explanations for these findings are given and the effects are discussed. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Microalgal process-monitoring based on high-selectivity spectroscopy tools: status and future perspectives.

    Science.gov (United States)

    Podevin, Michael; Fotidis, Ioannis A; Angelidaki, Irini

    2017-11-27

    Microalgae are well known for their ability to accumulate lipids intracellularly, which can be used for biofuels and mitigate CO 2 emissions. However, due to economic challenges, microalgae bioprocesses have maneuvered towards the simultaneous production of food, feed, fuel, and various high-value chemicals in a biorefinery concept. On-line and in-line monitoring of macromolecules such as lipids, proteins, carbohydrates, and high-value pigments will be more critical to maintain product quality and consistency for downstream processing in a biorefinery to maintain and valorize these markets. The main contribution of this review is to present current and prospective advances of on-line and in-line process analytical technology (PAT), with high-selectivity - the capability of monitoring several analytes simultaneously - in the interest of improving product quality, productivity, and process automation of a microalgal biorefinery. The high-selectivity PAT under consideration are mid-infrared (MIR), near-infrared (NIR), and Raman vibrational spectroscopies. The current review contains a critical assessment of these technologies in the context of recent advances in software and hardware in order to move microalgae production towards process automation through multivariate process control (MVPC) and software sensors trained on "big data". The paper will also include a comprehensive overview of off-line implementations of vibrational spectroscopy in microalgal research as it pertains to spectral interpretation and process automation to aid and motivate development.

  11. Damage Characterization and Real-Time Health Monitoring of Aerospace Materials Using Innovative NDE Tools

    Science.gov (United States)

    Matikas, Theodore E.

    2010-07-01

    The objective of this work is to characterize the damage and monitor in real-time aging structural components used in aerospace applications by means of advanced nondestructive evaluation techniques. Two novel experimental methodologies are used in this study, based on ultrasonic microscopy and nonlinear acoustics. It is demonstrated in this work that ultrasonic microscopy can be successfully utilized for local elastic property measurement, crack-size determination as well as for interfacial damage evaluation in high-temperature materials, such as metal matrix composites. Nonlinear acoustics enables real-time monitoring of material degradation in aerospace structures. When a sinusoidal ultrasonic wave of a given frequency and of sufficient amplitude is introduced into a nonharmonic solid, the fundamental wave distorts as it propagates, and therefore the second and higher harmonics of the fundamental frequency are generated. Measurements of the amplitude of these harmonics provide information on the coefficient of second- and higher-order terms of the stress-strain relation for a nonlinear solid. It is shown in this article that the material bulk nonlinear parameter for metallic alloy samples at different fatigue levels exhibits large changes compared to linear ultrasonic parameters, such as velocity and attenuation.

  12. InSAR as a volcano monitoring tool for Auckland City, New Zealand.

    Science.gov (United States)

    Stevens, N. F.; Miller, C. A.; Williams, C. A.

    2004-12-01

    Auckland City, New Zealand, with a population exceeding 1 million, is built directly on top of an active monogenetic volcanic field, which last erupted several hundred years ago. The field contains around 50 discrete volcanoes that have erupted over the last 250ka. The eruptions are typically small volume (Auckland region means that coherence between acquisitions persists for years, allowing long-term baselines to be established. Auckland magma is thought to ascend exceptionally rapidly. We undertook Mogi modelling of ascending volumes at different depths in the crust to simulate a rising diapir, and ascertained whether the precursive deformation signals are likely to be (a) within the detection limits of C-band InSAR, and (b) discernible above any atmospheric noise. As a result of our research, a program of regular radar data collection from the Envisat satellite has been established for monitoring purposes, with data collected every 3 months, ensuring that an adequate archive of suitable data is available for inter-comparison with future Envisat acquisitions, should a volcanic crisis occur. Once near-real-time data supply issues are totally overcome, the InSAR monitoring capability at Auckland will be fully operational.

  13. In situ ellipsometry — A powerful tool for monitoring alkali doping of organic thin films

    International Nuclear Information System (INIS)

    Haidu, F.; Ludemann, M.; Schäfer, P.; Gordan, O.D.; Zahn, D.R.T.

    2014-01-01

    The changes of the optical properties of several organic thin films induced by potassium doping were monitored using in situ spectroscopic ellipsometry. The samples were prepared in a high vacuum chamber by organic molecular deposition. Then, potassium (K) was evaporated by passing current through K getters. The three different organic molecules used, show very distinct and different spectral behaviour upon doping. While for Tris-(8-hydroxyquinoline)-aluminium(III) and N,N′-Di-[(1-naphthyl)-N,N′-diphenyl]-(1,1′-biphenyl)-4,4′-diamine only small shifts of the spectral features were noticed, Manganese Phthalocyanine revealed significant changes of the optical properties induced by the K doping. This work indicates that the K doping process can have a dramatic effect on the electronic and the optical properties of the organic molecules, but the effect on the optical spectra remains specific for each organic molecule used, and cannot be easily predicted. - Highlights: • Monitoring organic film growth and doping with in situ spectroscopic ellipsometry • K doped organic thin films • Optical properties of organic thin films change by K doping. • The changes in the optical spectra remain specific for each organic molecule used

  14. Comprehensive description of the photodegradation of bromophenols using chromatographic monitoring and chemometric tools.

    Science.gov (United States)

    Mas, Sílvia; Carbó, Albert; Lacorte, Sílvia; de Juan, Anna; Tauler, Romà

    2011-01-30

    A general procedure for the study of complex photodegradation processes of environmental pollutants based on chromatographic monitoring and chemometric method is proposed. The procedure consists of multiset data analysis of aliquots collected at different reaction times and injected in High-Performance Liquid Chromatography coupled to diode array detection and mass spectrometry (HPLC-DAD-MS). In this study, photodegradation of six bromophenols with different degrees of bromination has been investigated in order to find out their photodegradation pathways and kinetics and to show the potential of the procedure proposed. Multivariate curve resolution-alternating least squares (MCR-ALS) has been used to resolve chromatographic elution profiles and pure spectra of species involved in the photodegradation process and, hence, to elucidate the photodegradation mechanism and to propose the chemical structure of the main photoproducts. This study shows that chromatographic monitoring is the preferred option when photochemical systems with large number of components with similar spectra and kinetic evolution are analyzed. This work reveals the advantages of the double DAD and MS detection to provide mechanistic and structural information about these complex photodegradation processes. Copyright © 2010 Elsevier B.V. All rights reserved.

  15. Molecular Tools to Monitor Microbial Contaminants During Long-Term Exploration Class Missions

    Science.gov (United States)

    Larios-Sanz, M.; Kourentzi, K.; Willson, R.; Pierson, D.; Fox, G.

    Microbial contaminants will inevitably accompany a human crew in our adventures into space. Humans constantly shed large numbers of microorganisms into the environment, and during spaceflight some normally benign microbes may become pathogenic. Concerns about microbial disease during Exploration Class human space missions are particularly important in light of the clinically significant changes that the immune system undergoes during spaceflight. Additionally, increased microbial burdens on closed air and water systems may lead to disease and become dangerous sources of contamination for replacement crews. These microbes might also become a serious threat to regenerative life support systems. The development of a robust system to detect, identify and monitor these contaminants i therefore critical. Wes are currently developing a monitoring system that employs 16S ribosomal RNA sequence information to identify bacterial contaminants at the genus and species level. Despite extensive secondary structure, a large number of regions on the 16S rRNA molecule have been successfully targeted. Probes specific for certain groups, such as "all bacteria", "Gram positives", "Gram negatives", and "enterics", as well as some targeting specific genera and species have been designed and optimized. A set of working probes is now being tested in a variety of solution assays that exploit new and exciting technologies such as molecular beacons and DNA microarrays.

  16. Satellite-based hybrid drought monitoring tool for prediction of vegetation condition in Eastern Africa: A case study for Ethiopia

    Science.gov (United States)

    Tadesse, Tsegaye; Demisse, Getachew Berhan; Zaitchik, Ben; Dinku, Tufa

    2014-03-01

    An experimental drought monitoring tool has been developed that predicts the vegetation condition (Vegetation Outlook) using a regression-tree technique at a monthly time step during the growing season in Eastern Africa. This prediction tool (VegOut-Ethiopia) is demonstrated for Ethiopia as a case study. VegOut-Ethiopia predicts the standardized values of the Normalized Difference Vegetation Index (NDVI) at multiple time steps (weeks to months into the future) based on analysis of "historical patterns" of satellite, climate, and oceanic data over historical records. The model underlying VegOut-Ethiopia capitalizes on historical climate-vegetation interactions and ocean-climate teleconnections (such as El Niño and the Southern Oscillation (ENSO)) expressed over the 24 year data record and also considers several environmental characteristics (e.g., land cover and elevation) that influence vegetation's response to weather conditions to produce 8 km maps that depict future general vegetation conditions. VegOut-Ethiopia could provide vegetation monitoring capabilities at local, national, and regional levels that can complement more traditional remote sensing-based approaches that monitor "current" vegetation conditions. The preliminary results of this case study showed that the models were able to predict the vegetation stress (both spatial extent and severity) in drought years 1-3 months ahead during the growing season in Ethiopia. The correlation coefficients between the predicted and satellite-observed vegetation condition range from 0.50 to 0.90. Based on the lessons learned from past research activities and emerging experimental forecast models, future studies are recommended that could help Eastern Africa in advancing knowledge of climate, remote sensing, hydrology, and water resources.

  17. Monitoring of in vitro dynamics of Acanthamoeba strains isolated from infected eyes as a useful tool in keratitis management.

    Science.gov (United States)

    Chomicz, Lidia; Padzik, Marcin; Szaflik, Jacek P; Nahorski, Wacław L; Kryczka, Tomasz; Szaflik, Jerzy

    2014-11-01

    Free-living amoebae of Acanthamoeba genus are ubiquitous in various parts of the world. Some species of these amoebozoans present a serious risk to human health as the causative agents of vision-threatening diseases, Acanthamoeba keratitis. Correct diagnosis requires both a clinical examination of the cornea and amoebic form identification in affected eyes. Despite advances in pharmacotherapy, the infection is difficult to diagnose and to threat. Population dynamics of five different Acanthamoeba strains cultured in vitro under bacteria-free condition in BSC medium, was monitored in terms of diagnostic and therapeutic management. The range of protozoan number in the exponential growth phase, the morpho-physiological status of amoeba forms and their ability to multiply were evaluated. Results of the studies revealed that early and continued monitoring of the strains maintained in an axenic culture showed correlation between the dynamics of cultivated amoebae and the course of the disease, differences in response to pharmacotherapy and the surgical management efficacy. Concluding, the in vitro monitoring of dynamics of Acanthamoeba strains isolated from infected corneas may be important not only for proper diagnosis but also as a useful tool in keratitis management and therapeutic prognosis. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Virtual Reality Simulation as a Tool to Monitor Surgical Performance Indicators: VIRESI Observational Study.

    Science.gov (United States)

    Muralha, Nuno; Oliveira, Manuel; Ferreira, Maria Amélia; Costa-Maia, José

    2017-05-31

    Virtual reality simulation is a topic of discussion as a complementary tool to traditional laparoscopic surgical training in the operating room. However, it is unclear whether virtual reality training can have an impact on the surgical performance of advanced laparoscopic procedures. Our objective was to assess the ability of the virtual reality simulator LAP Mentor to identify and quantify changes in surgical performance indicators, after LAP Mentor training for digestive anastomosis. Twelve surgeons from Centro Hospitalar de São João in Porto (Portugal) performed two sessions of advanced task 5: anastomosis in LAP Mentor, before and after completing the tutorial, and were evaluated on 34 surgical performance indicators. The results show that six surgical performance indicators significantly changed after LAP Mentor training. The surgeons performed the task significantly faster as the median 'total time' significantly reduced (p virtual reality training simulation as a benchmark tool to assess the surgical performance of Portuguese surgeons. LAP Mentor is able to identify variations in surgical performance indicators of digestive anastomosis.

  19. Infrasound as a Long Standing Tool for Monitoring Continental Ecuadorean Volcanoes

    Science.gov (United States)

    Ruiz, M. C.; Ortiz, H. D.; Hernandez, S.; Palacios, P.; Anzieta, J. C.

    2017-12-01

    In the last 10 years, infrasound and seismic methods have been successfully used in the continuous monitoring of eruptive activity at Tunguruhua, Reventador, Sangay and Cotopaxi volcanoes. After a dormant period of 81 years, Tungurahua woke up in 1999 and has since been characterized by vulcanian and strombolian eruptions. Beginning in July 2006, a permanent seismo-infrasonic network with 5 collocated seismic and infrasound sensors was installed through a cooperation with Japan International Cooperation Agency (JICA). It recorded more than 6,000 explosions at Tungurahua with reduced amplitudes larger than 270 Pa at 1 km from the active crater, including 3 explosions greater than 6000 Pa associated with short-lived explosions. Major and long sustained eruptions (July 14-15, 2006; August 16-17, 2006; February 6-8, 2008, May 28, 2010; December 4, 2010; December 3-4, 2011; August 18, 2012) generated seismic and infrasound tremors with complex waveforms. In 2002, Reventador volcano produced the largest eruption in Ecuador in the last century (VEI-4). Since September 2012, alternating periods of strombolian activity and short-lived vulcanian explosions are monitored by seismic and microbarometer sensors located on the south-east border of the caldera rim. Non-steady activity with fluctuations between quiescence and frequent explosions, tremor, and chugging events is recorded. Infrasound of explosions ranges from 75 to 6350 Pa in reduced peak-to-peak amplitudes. Sangay, a remote and very active volcano, is monitored by a broadband seismometer and microbarometer collocated at 8 km from the summit. Active periods during the last few months are characterized by explosion events followed by lava flows and small ash emissions. In March 2016, more than 100 explosions were recorded in a single day. Finally, in 2015 Cotopaxi volcano began its recent eruptive period after 138 years of quiescence. One month after the initiation of its eruptive activity, 76 harmonic infrasound

  20. Assessment of the global trigger tool to measure, monitor and evaluate pateint safety in cancer patients

    DEFF Research Database (Denmark)

    Otto Mattsson, Thea; Lehmann-Knudsen, Janne; Lauritsen, Jens M

    2013-01-01

    on identical charts by two independent review teams in 2010 at a department of oncology in a university hospital. Standard GTT outcome measurements were obtained and compared between teams using statistical process control (SPC) charts. A Bland-Altman plot assessed measurement error and limits of agreement....... RESULTS: Only 31% of adverse events (AE) were identified by both teams, and further differences in categorisation of identical events was found. Moderate interrater agreement (κ=0.45) between teams gave rise to different conclusions on the patient safety process when monitoring using SPC charts. The Bland......-Altman plot suggests little systematic error but large random error. CONCLUSIONS: Review teams may identify different AE and reach different conclusions on the safety process when using the GTT on identical charts. Tracking true change in the safety level is difficult due to measurement error of the GTT...

  1. Characterization of GEM foils and materials simulation, measurements and interferometric monitoring tools

    CERN Document Server

    Benussi, Luigi

    2015-01-01

    The GE1/1 CMS project consists of 144 GEM chambers of about 0.5 qm active area each, based on the triple GEMs technology, to be installed in the very forward region of the CMS endcap during the long shutdown of LHC in 2108-2019. GE1/1 chambers will be operated for decades in harsh environment, and are expected to perform consistently providing good space and time resolution and excellent rate capabilities. An extensive material science simulation and measurement campaign is in progress to characterize GEM materials, with main focus on the GEM foils. Results are presented on full Finite Element Analysis simulations, measurement of tensile properties and humidity absorption coefficients, both for unused and irradiated samples. Preliminary results are shown on interferometric methods based on Moirè fringes for the monitoring of GEM foils mechanical properties during chamber construction.

  2. Predictive analytics tools to adjust and monitor performance metrics for the ATLAS Production System

    CERN Document Server

    Titov, Mikhail; The ATLAS collaboration

    2017-01-01

    Every scientific workflow involves an organizational part which purpose is to plan an analysis process thoroughly according to defined schedule, thus to keep work progress efficient. Having such information as an estimation of the processing time or possibility of system outage (abnormal behaviour) will improve the planning process, provide an assistance to monitor system performance and predict its next state. The ATLAS Production System is an automated scheduling system that is responsible for central production of Monte-Carlo data, highly specialized production for physics groups, as well as data pre-processing and analysis using such facilities as grid infrastructures, clouds and supercomputers. With its next generation (ProdSys2) the processing rate is around 2M tasks per year that is more than 365M jobs per year. ProdSys2 evolves to accommodate a growing number of users and new requirements from the ATLAS Collaboration, physics groups and individual users. ATLAS Distributed Computing in its current stat...

  3. Space Based Measurements for Atmospheric Carbon Dioxide: a New Tool for Monitoring Our Environment

    Science.gov (United States)

    Crisp, David

    2015-01-01

    Fossil fuel combustion, deforestation, and other human activities are now adding almost 40 billion tons of carbon dioxide (CO2) to the atmosphere each year. Interestingly, as these emissions have increased over time, natural "sinks" in land biosphere and oceans have absorbed roughly half of this CO2, reducing the rate of atmospheric buildup by a half. Measurements of the increasing acidity (pH) of seawater indicate that the ocean absorbs one quarter of this CO2. Another quarter is apparently being absorbed by the land biosphere, but the identity and location of these natural land CO2 "sinks" are still unknown. The existing ground-based greenhouse gas monitoring network provides an accurate record of the atmospheric buildup, but still does not have the spatial resolution or coverage needed to identify or quantify CO2 sources and sinks.

  4. saltPAD: A New Analytical Tool for Monitoring Salt Iodization in Low Resource Settings

    Directory of Open Access Journals (Sweden)

    Nicholas M. Myers

    2016-03-01

    Full Text Available We created a paper test card that measures a common iodizing agent, iodate, in salt. To test the analytical metrics, usability, and robustness of the paper test card when it is used in low resource settings, the South African Medical Research Council and GroundWork performed independ‐ ent validation studies of the device. The accuracy and precision metrics from both studies were comparable. In the SAMRC study, more than 90% of the test results (n=1704 were correctly classified as corresponding to adequately or inadequately iodized salt. The cards are suitable for market and household surveys to determine whether salt is adequately iodized. Further development of the cards will improve their utility for monitoring salt iodization during production.

  5. Checklists: An under-used tool for the inventory and monitoring of plants and animals

    Science.gov (United States)

    Droege, S.; Cyr, A.; Larivee, J.

    1998-01-01

    Checklists are widely used to catalog field observations of plants and animals. We used 25 years of bird checklist data from the Etudes des Populations d'Oiseaux du Quebec program to examine the ability of checklists to produce reliable conservation, management, and ecological information. We found that checklists can provide reliable information on changes in bird populations, phenology, and geographic and climate abundance patterns at local, regional, and continental scales. Professional and amateur conservation groups that need to develop extensive monitoring programs should take advantage of the fact that checklists, unlike other time-consuming and expensive techniques, can be used to detect large-scale changes in an entire community of species.

  6. Rain Check Application: Mobile tool to monitor rainfall in remote parts of Haiti

    Science.gov (United States)

    Huang, X.; Baird, J.; Chiu, M. T.; Morelli, R.; de Lanerolle, T. R.; Gourley, J. R.

    2011-12-01

    Rainfall observations performed uniformly and continuously over a period of time are valuable inputs in developing climate models and predicting events such as floods and droughts. Rain-Check is a mobile application developed in Google App Inventor Platform, for android based smart phones, to allow field researchers to monitor various rain gauges distributed though out remote regions of Haiti and send daily readings via SMS messages for further analysis and long term trending. Rainfall rate and quantity interact with many other factors to influence erosion, vegetative cover, groundwater recharge, stream water chemistry and runoff into streams impacting agriculture and livestock. Rainfall observation from various sites is especially significant in Haiti with over 80% of the country is mountainous terrain. Data sets from global models and limited number of ground stations do not capture the fine-scale rainfall patterns necessary to describe local climate. Placement and reading of rain gauges are critical to accurate measurement of rainfall.

  7. Methods and Tools for Measurement,Monitoring and Verification for Soil Carbon Sequestration (Invited)

    Science.gov (United States)

    Rice, C. W.

    2009-12-01

    Agriculture, forests, and other working lands, when properly managed, provide low cost and viable options for reducing greenhouse gas (GHG) emissions while providing additional carbon (C) sinks. These lands in the United States (U.S.) have the capacity to sequester about 650 million metric tons of carbon dioxide (CO2) every year, offsetting up to 11 % of U.S. greenhouse gas (GHG) emissions annually. However to fully account for soil changes in soil c requires better measuring and monitoring sustems. To meet this interest a transparent and verifiable accounting system for estimating the amounts and uncertainties of soil carbon stock changes and greenhouse gas (GHG) emissions is needed at multiple scales. The accounting system must include climate, land use and management databases linked to ecological models and temporal and spatial scaling processes. Protocols need to be established for measurement of soil C stock changes and trace gas emissions and develop methodologies for monitoring soil C stock changes and trace gas emissions. The objective of this paper is to synthesize critical issues and methodological advances made to detect changes in soil C at the field and regional scales as a result of changes in management or land use. New technologies for soil C measurements can help reduce costs and time for C measurements. New technologies include Laser Induced Breakdown Spectroscopy (LIBS), Mid Infra Red Spectroscopy (MIRS), Inelastic Neutron Scattering (INS) and dry combustion. Elements of an accounting system must be based on the best science available to provide accurate estimates of GHG sources and sinks within resource constraints; be verifiable by an independent third party; and be able to incorporate new data at finer resolutions as becomes more readily available. At present the system could utilize sites for physical measurements, existing databases, and models and remote sensing to extrapolate to larger scales. International collaboration will help develop

  8. Efficient Data Assimilation Tool For Real Time CO2 Reservoir Monitoring and Characterization

    Science.gov (United States)

    Li, J. Y.; Ambikasaran, S.; Kokkinaki, A.; Darve, E. F.; Kitanidis, P. K.

    2014-12-01

    Reservoir forecasting and management are increasingly relying on a data-driven approach, which involves data assimilation to calibrate and keep up to date the complex model of multi-phase flow and transport in the geologic formation and to evaluate its uncertainty using monitoring data of different types and temporal resolution. The numbers of unknowns and measurements are usually very large, which represents a major computational challenge. Kalman filter (KF), the archetypical recursive filter, provides the framework to assimilate reservoir monitoring data into a dynamic system but the cost of implementing the original algorithm to large systems is computationally prohibitive. In our work, we have developed several Kalman-filter based approaches that reduce the computational and storage cost of standard KF from O (m2) to O (m), where m is the number of unknowns, and have the potential to be applied to field-scale problems. HiKF, a linear filter based on the hierarchical matrix approach, takes advantage of the informative high-frequency data acquired quasi-continuously and uses a random-walk model in the state forecast step when the a state evolution model is unavailable. A more general-purpose nonlinear filter CSKF achieves computational efficiency by exploiting the fact that the state covariance matrix for most dynamical systems can be approximated adequately through a low-rank matrix, and it allows using a forward simulator as a black-box for nonlinear error propagation. We will demonstrate both methods using synthetic CO2 injection cases and compare with the standard ensemble Kalman filter (EnKF).

  9. Reliability of periodontal diagnostic tools for monitoring peri-implant health and disease.

    Science.gov (United States)

    Coli, Pierluigi; Christiaens, Véronique; Sennerby, Lars; Bruyn, Hugo De

    2017-02-01

    The prevalence, causes and consequences of crestal bone loss at dental implants are a matter of debate. In recent years, a high prevalence of peri-implant soft-tissue inflammation, associated with peri-implant bone loss, has been reported and the need for treatments similar to those offered for natural teeth affected by periodontitis has been proposed. This suggestion is based on the assumption that periodontal indices, such as probing pocket depth and bleeding on probing, are reliable indicators of the peri-implant tissue conditions and good predictors of future bone loss. However, based on a critical review of the literature in the present paper, it is concluded that periodontal indices are not reliable either for identifying peri-implant disease or for predicting future risk for peri-implant crestal bone loss and implant failure. The long-term experiences with dental implants, presented in the literature, indicate that the presence of bleeding on probing, probing pocket depths much larger than 4 mm and some bone loss seem to reflect, in most instances, normal conditions of well-functioning dental implants, bearing in mind that healing of dental implants is the result of a foreign body reaction with the formation of scar tissue. Therefore, the use of probing pocket depth and bleeding on probing assessments may lead to over-diagnosis and possibly to over-treatment of assumed biofilm-mediated peri-implantitis lesions. It is the opinion of the authors of this review that a treatment should only be initiated when a clinical problem is present based on patient's symptoms (discomfort, pain), the presence of swelling, redness and pus, and significant crestal bone loss over time (as verified with radiographs). The treatment should aim at resolving the infection, which could include removal of the implant. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Seroepidemiology: an underused tool for designing and monitoring vaccination programmes in low- and middle-income countries.

    Science.gov (United States)

    Cutts, Felicity T; Hanson, Matt

    2016-09-01

    Seroepidemiology, the use of data on the prevalence of bio-markers of infection or vaccination, is a potentially powerful tool to understand the epidemiology of infection before vaccination and to monitor the effectiveness of vaccination programmes. Global and national burden of disease estimates for hepatitis B and rubella are based almost exclusively on serological data. Seroepidemiology has helped in the design of measles, poliomyelitis and rubella elimination programmes, by informing estimates of the required population immunity thresholds for elimination. It contributes to monitoring of these programmes by identifying population immunity gaps and evaluating the effectiveness of vaccination campaigns. Seroepidemiological data have also helped to identify contributing factors to resurgences of diphtheria, Haemophilus Influenzae type B and pertussis. When there is no confounding by antibodies induced by natural infection (as is the case for tetanus and hepatitis B vaccines), seroprevalence data provide a composite picture of vaccination coverage and effectiveness, although they cannot reliably indicate the number of doses of vaccine received. Despite these potential uses, technological, time and cost constraints have limited the widespread application of this tool in low-income countries. The use of venous blood samples makes it difficult to obtain high participation rates in surveys, but the performance of assays based on less invasive samples such as dried blood spots or oral fluid has varied greatly. Waning antibody levels after vaccination may mean that seroprevalence underestimates immunity. This, together with variation in assay sensitivity and specificity and the common need to take account of antibody induced by natural infection, means that relatively sophisticated statistical analysis of data is required. Nonetheless, advances in assays on minimally invasive samples may enhance the feasibility of including serology in large survey programmes in low

  11. Remote monitoring improves outcome after ICD implantation: the clinical efficacy in the management of heart failure (EFFECT) study.

    Science.gov (United States)

    De Simone, Antonio; Leoni, Loira; Luzi, Mario; Amellone, Claudia; Stabile, Giuseppe; La Rocca, Vincenzo; Capucci, Alessandro; D'onofrio, Antonio; Ammendola, Ernesto; Accardi, Francesco; Valsecchi, Sergio; Buja, Gianfranco

    2015-08-01

    Internet-based remote interrogation systems have been shown to reduce emergency department and in-office visits in patients with implantable cardioverter defibrillators (ICDs), resulting in increased efficiency for healthcare providers. Nonetheless, studies sized to demonstrate the impact of remote monitoring on patients' outcome have been lacking. The EFFECT study was a multicentre clinical trial aimed at measuring and comparing the outcome of ICD patients conventionally followed-up by means of in-clinic visits (Standard arm) or by remote monitoring (Remote arm) in the clinical practice of 25 Italian centres. From 2011 to 2013, 987 consecutive patients were enrolled and followed up for at least 12 months. The primary endpoint was the rate of death and cardiovascular hospitalizations. Remote monitoring was adopted by 499 patients. Patients in the Standard and Remote arms did not differ significantly in terms of baseline clinical characteristics, except for a more frequent use of ICD with cardiac resynchronization therapy (CRT-D) in the Remote arm (48 vs. 36%, P Remote arm (incident rate ratio, 0.55; 95% CI, 0.41-0.73; P Remote arms were 0.27 and 0.08 events/year, respectively, among CRT-D recipients (P Remote arm. Compared with the standard follow-up through in-office visits, remote monitoring is associated with reduced death and cardiovascular hospitalizations in patients with ICD in clinical practice. URL: http://clinicaltrials.gov/ Identifier: NCT01723865. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.

  12. Tree-Ring Nitrogen Isotopes As Environmental Monitoring Tools - Inferring Air Quality Changes And Climate Effects

    Science.gov (United States)

    Savard, M. M.; Begin, C.; Smirnoff, A.; Marion, J.

    2008-12-01

    Anthropogenic emissions of atmospheric nitrogen greatly increased over the last 150 years, however the monitoring of nitrous oxide concentration in North America started only recently, generally during the last 30 years. Could the geochemical characteristics of tree rings be used to infer past changes in nitrogen cycles of temperate regions? To address this question we use long-term series (125 years) of nitrogen stable isotopes (δ15N) obtained from rings of pine (Pinus strobus) and beech (Fagus grandifolia) trees in the Montreal region (western Quebec), and of beech specimens in the Georgian Bay Islands National Park (central Ontario). Reliability tests of N concentrations in wood treated for removal of soluble materials reveal that the reproducibility from tree to tree is poor, and that the concentrations in both Pine and Beech trees change in the heartwood-sapwood transition zones. We therefore reject N concentration as environmental indicator. Alternatively, the N stable isotopes pass all reliability tests. In Montreal, short-term δ15N fluctuations correlate directly with precipitation and inversely with temperature. A long-term decreasing isotope trend suggests progressive changes in soil chemistry after 1951. A pedochemical change is also inferred for the Georgian Bay site on the basis of a positive δ15N trend initiated after 1971. At both sites, the long-term δ15N series correlate with a proxy for NOx emissions, and the δ13C values of the same ring series suggest that all studied trees have been stressed by phytotoxic pollutants. We propose that the contrasted long-term δ15N changes of Montreal and Georgian Bay reflect deposition of NOx emissions from cars and coal-power plants, with higher proportions from coal burning in Georgian Bay. This interpretation is conceivable because recent monitoring indicates that coal-power plant NOx emissions play an important role in the annual N budget in Ontario, but they seem negligible on the Quebec side. This

  13. Real-time Seismic Amplitude Measurement (RSAM): a volcano monitoring and prediction tool

    Science.gov (United States)

    Endo, E.T.; Murray, T.

    1991-01-01

    Seismicity is one of the most commonly monitored phenomena used to determine the state of a volcano and for the prediction of volcanic eruptions. Although several real-time earthquake-detection and data acquisition systems exist, few continuously measure seismic amplitude in circumstances where individual events are difficult to recognize or where volcanic tremor is prevalent. Analog seismic records provide a quick visual overview of activity; however, continuous rapid quantitative analysis to define the intensity of seismic activity for the purpose of predicing volcanic eruptions is not always possible because of clipping that results from the limited dynamic range of analog recorders. At the Cascades Volcano Observatory, an inexpensive 8-bit analog-to-digital system controlled by a laptop computer is used to provide 1-min average-amplitude information from eight telemetered seismic stations. The absolute voltage level for each station is digitized, averaged, and appended in near real-time to a data file on a multiuser computer system. Raw realtime seismic amplitude measurement (RSAM) data or transformed RSAM data are then plotted on a common time base with other available volcano-monitoring information such as tilt. Changes in earthquake activity associated with dome-building episodes, weather, and instrumental difficulties are recognized as distinct patterns in the RSAM data set. RSAM data for domebuilding episodes gradually develop into exponential increases that terminate just before the time of magma extrusion. Mount St. Helens crater earthquakes show up as isolated spikes on amplitude plots for crater seismic stations but seldom for more distant stations. Weather-related noise shows up as low-level, long-term disturbances on all seismic stations, regardless of distance from the volcano. Implemented in mid-1985, the RSAM system has proved valuable in providing up-to-date information on seismic activity for three Mount St. Helens eruptive episodes from 1985 to

  14. Novel experimental methods for investigating high speed friction of titanium-aluminum-vanadium/tool steel interface and dynamic failure of extrinsically toughened DRA composites

    Science.gov (United States)

    Irfan, Mohammad Abdulaziz

    Dynamic deformation, flow, and failure are integral parts of all dynamic processes in materials. Invariably, dynamic failure also involves the relative sliding of one component of the material over the other. Advances in elucidation of these failure mechanisms under high loading rates has been of great interest to scientists working in this area. The need to develop new dynamic mechanical property tests for materials under well characterized and controllable loading conditions has always been a challenge to experimentalists. The current study focuses on the development of two experimental methods to study some aspects of dynamic material response. The first part focuses on the development of a single stage gas gun facility for investigating high-speed metal to metal interfacial friction with applications to high speed machining. During the course of this investigation a gas gun was designed and built capable of accelerating projectiles upto velocities of 1 km/s. Using this gas gun pressure-shear plate impact friction experiments were conducted to simulate conditions similar to high speed machining at the tool-workpiece interface. The impacting plates were fabricated from materials representing the tribo-pair of interest. Accurate measurements of the interfacial tractions, i.e. the normal pressure and the frictional stress at the tribo-pair interface, and the interfacial slip velocity could be made by employing laser interferometry. Normal pressures of the order of 1-2 MPa were generated and slipping velocities of the order of 50 m/s were obtained. In order to illustrate the structure of the constitutive law governing friction, the study included experimental investigation of frictional response to step changes in normal pressure and interfacial shear stress. The results of these experiments indicate that sliding resistance for Ti6Al4V/CH steel interface is much lower than measured under quasi-static sliding conditions. Also the temperature at the interface strongly

  15. Ribosomal intergenic spacer analysis as a tool for monitoring methanogenic Archaea changes in an anaerobic digester.

    Science.gov (United States)

    Ciesielski, Slawomir; Bułkowska, Katarzyna; Dabrowska, Dorota; Kaczmarczyk, Dariusz; Kowal, Przemyslaw; Możejko, Justyna

    2013-08-01

    The applicability of a newly-designed PCR primer pair in examination of methanogenic Archaea in a digester treating plant biomass was evaluated by Ribosmal Intergenic Spacer Analysis (RISA). To find a suitable approach, three variants of RISA were tested: (1) standard, polyacrylamide gel-based, (2) automated, utilized capillary electrophoresis (GA-ARISA), and (3) automated microfluidics-based (MF-ARISA). All three techniques yielded a consistent picture of archaeal community structure changes during anaerobic digestion monitored for more than 6 weeks. While automated variants were more practical for handling and rapid analysis of methanogenic Archaea, the gel-based technique was advantageous when micro-organism identification was required. A DNA-sequence analysis of dominant bands extracted from the gel revealed that the main role in methane synthesis was played by micro-organisms affiliated with Methanosarcina barkeri. The obtained results revealed that RISA is a robust method allowing for detailed analysis of archaeal community structure during organic biomass conversion into biogas. In addition, our results showed that GA-ARISA has a higher resolution and reproducibility than other variants of RISA and could be used as a technique for tracking changes in methanogenic Archaea in an anaerobic digester.

  16. Monitoring survival of Lactobacillus casei ATCC 393 in probiotic yogurts using an efficient molecular tool.

    Science.gov (United States)

    Sidira, Marianthi; Saxami, Georgia; Dimitrellou, Dimitra; Santarmaki, Valentini; Galanis, Alex; Kourkoutas, Yiannis

    2013-05-01

    The aim of the present study was to monitor the survival of the probiotic strain Lactobacillus casei ATCC 393 during refrigerated storage of natural regular yogurts compared with Lactobacillus delbrueckii ssp. bulgaricus. Both free and immobilized cells on supports of high industrial interest, such as fruits and oat pieces, were tested. Microbiological and strain-specific multiplex PCR analysis showed that both free and immobilized Lb. casei ATCC 393 were detected in the novel products at levels required to confer a probiotic effect (at least 6 log cfu/g) for longer periods than required by the dairy industry (≥ 30 d) during storage at 4°C. In contrast, the viable bacterial density of Lb. delbrueckii ssp. bulgaricus decreased to levels pH of all products was 4.2 to 4.3. Acid resistance or cold tolerance of Lb. casei ATCC 393 apparently allows for increased survival compared with Lb. delbrueckii ssp. bulgaricus in these yogurt formulations. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  17. The utility of mosquito-borne disease as an environmental monitoring tool in tropical ecosystems.

    Science.gov (United States)

    Jardine, Andrew; Cook, Angus; Weinstein, Philip

    2008-12-01

    The intrinsic link between ecosystem health and human health has been firmly established in the literature and has given rise to the development of new multidisciplinary fields of research such as medical geology. An important practical implication of the ecosystem health approach is the utility of human disease outbreaks as indicators of underlying ecosystem disruption. The use of such a bioindicator is particularly relevant in developing countries where monitoring of traditional environmental and ecological indicators is not routinely undertaken. Mosquito-borne diseases appear to have good potential as bioindicators in tropical regions because the burden of disease is high, the disease ecology has a strong environmental component and intensive surveillance systems are well established. Evidence is reviewed regarding the utility of mosquito-borne disease to detect a range of ecosystem insults including: hydro-geological disruption in soil-water systems (e.g. secondary soil salinisation and waterlogging); escalating agricultural intensification; deforestation; and urbanisation. The evidence suggests that overall, mosquito-borne disease is a specific but insensitive indicator, because human modification of natural ecosystems does not always result in increases in disease incidence and can, in some cases, lead to reductions. Nevertheless, mosquito-borne disease remain useful as bioindicators if utilised as a complement to traditional environmental variables in identifying ecological disturbances; they can then assist in directing interventions that are concurrently beneficial to both human health and ecosystem health.

  18. Reflectance spectroscopy is an effective tool for monitoring soot pollution in an urban suburb.

    Science.gov (United States)

    Saaroni, H; Chudnovsky, A; Ben-Dor, E

    2010-02-01

    This study examines whether converting the fossil fuel of the Tel Aviv power station from oil to gas influences air pollution in the local urban environment. To this end, the spectral properties of accumulated dust on tree leaves and paper bags were assessed before (2004) and after (2006) the conversion. The sampling site was a garden in a neighborhood located 2700m downwind of the power station. In addition, air pollution concentrations and particulate matter parameters recorded by a local meteorological station were analyzed (PM(10), NO(x), NO(2), NO, and SO(2)). Although differences in the average monthly concentration of pollution parameters are mostly insignificant between the two periods, the accumulated particulate matter exhibits considerably different spectral patterns. All first period samples exhibit a distinctly concave slope in the spectral region between 400 and 1400nm, indicative of high amounts of soot, most likely due to the combustion products of fuel oil exhausted by the power plant. In contrast, the second period samples exhibit spectra that indicate reduced soot content and even appear slightly convex, evidencing the presence of dust of mineral origin, a feature likely masked by the soot in the first period. Thus, the spectral data support that the power plant conversion results in less pollution. More generally, this study corroborates that VIS-NIR-SWIR spectroscopy characterizes key properties of the particulate layer accumulating on sampled surfaces and thus, is a powerful method for monitoring the urban environment. Copyright 2009 Elsevier B.V. All rights reserved.

  19. Infrared thermography: A potential noninvasive tool to monitor udder health status in dairy cows

    Directory of Open Access Journals (Sweden)

    M. Sathiyabarathi

    2016-10-01

    Full Text Available The animal husbandry and livestock sectors play a major role in the rural economy, especially for the small and marginal farmers. India has the largest livestock population in the world and ranks first in the milk production. Mastitis is the most common and expensive infectious disease in dairy cattle. The global economic losses per year due to mastitis amounts to USD 35 billion and for Indian dairy industry INR 6000 crores per year. Early detection of mastitis is very important to reduce the economic loss to the dairy farmers and dairy industry. Automated methods for early and reliable detection of mastitis are currently in focus under precision dairying. Skin surface temperature is an important indicator for the diagnosis of cow’s illnesses and for the estimation of their physiological status. Infrared thermography (IRT is a simple, effective, on-site, and noninvasive method that detects surface heat, which is emitted as infrared radiation and generates pictorial images without causing radiation exposure. In human and bovine medicine, IRT is used as a diagnostic tool for assessment of normal and physiological status.

  20. A voltammetric electronic tongue as tool for water quality monitoring in wastewater treatment plants.

    Science.gov (United States)

    Campos, Inmaculada; Alcañiz, Miguel; Aguado, Daniel; Barat, Ramón; Ferrer, José; Gil, Luis; Marrakchi, Mouna; Martínez-Mañez, Ramón; Soto, Juan; Vivancos, José-Luis

    2012-05-15

    The use of a voltammetric electronic tongue as tool for the prediction of concentration levels of certain water quality parameters from influent and effluent wastewater from a Submerged Anaerobic Membrane Bioreactor pilot plant applied to domestic wastewater treatment is proposed here. The electronic tongue consists of a set of noble (Au, Pt, Rh, Ir, and Ag) and non-noble (Ni, Co and Cu) electrodes that were housed inside a stainless steel cylinder which was used as the body of the electronic tongue system. As a previous step an electrochemical study of the response of the ions sulphate, orthophosphate, acetate, bicarbonate and ammonium was carried out in water using the electrodes contained in the electronic tongue. The second part of the work was devoted to the application of the electronic tongue to the characterization of the influent and effluent waters from the wastewater treatment plant. Partial Least Squares analysis was used to obtain a correlation between the data from the tongue and the pollution parameters measured in the laboratory such as soluble chemical oxygen demand (CODs), soluble biological oxygen demand (BODs), ammonia (NH(4)-N), orthophosphate (PO(4)-P), Sulphate (SO(4)-S), acetic acid (HAC) and alkalinity (Alk). A total of 28 and 11 samples were used in the training and the validation steps, respectively, for both influent and effluent water samples. The electronic tongue showed relatively good predictive power for the determination of BOD, COD, NH(4)-N, PO(4)-P, SO(4)-S, and Alk. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Exploring JavaScript and ROOT technologies to create Web-based ATLAS analysis and monitoring tools

    CERN Document Server

    Sanchez, Arturo; The ATLAS collaboration

    2015-01-01

    We explore the potentialities of current web applications to create online interfaces that allow the visualization, interaction and real physics cut-based analysis and monitoring of processes trough a web browser. The project consists in the initial development of web-based and cloud computing services to allow students and researches to perform fast and very useful cut-based analysis on a browser, reading and using real data and official Monte-Carlo simulations stored in ATLAS computing facilities. Several tools are considered: ROOT, JavaScript and HTML. Our study case is the current cut-based H->ZZ->llqq analysis of the ATLAS experiment. Preliminary but satisfactory results have been obtained online; this presentation describes the tests and plans and future upgrades.

  2. Exploring JavaScript and ROOT technologies to create Web-based ATLAS analysis and monitoring tools

    CERN Document Server

    Pineda, A S

    2015-01-01

    We explore the potential of current web applications to create online interfaces that allow the visualization, interaction and real cut-based physics analysis and monitoring of processes through a web browser. The project consists in the initial development of web- based and cloud computing services to allow students and researchers to perform fast and very useful cut-based analysis on a browser, reading and using real data and official Monte- Carlo simulations stored in ATLAS computing facilities. Several tools are considered: ROOT, JavaScript and HTML. Our study case is the current cut-based H → ZZ → llqq analysis of the ATLAS experiment. Preliminary but satisfactory results have been obtained online.

  3. Foraminiferal single chamber analyses of heavy metals as a tool for monitoring permanent and short term anthropogenic footprints.

    Science.gov (United States)

    Titelboim, Danna; Sadekov, Aleksey; Hyams-Kaphzan, Orit; Almogi-Labin, Ahuva; Herut, Barak; Kucera, Michal; Abramovich, Sigal

    2018-03-01

    In order to establish environmentally sustainable industries there is a need for high-resolution temporal and spatial monitoring of heavy metal pollutants even at low concentrations before they become hazardous for local ecosystems. Here we present single chamber records of Cu, Zn and Pb in shells of two benthic foraminifera species with different shell types from two shallow coastal stations in Israel: An area adjacent to an electrical power plant and desalination factory (Hadera) and an industrially free nature reserve (Nachsholim). Records of both foraminifera species show elevated metal concentrations in Hadera clearly identifying the footprint of the local industrial facilities. Moreover, short-term events of elevated Cu and Pb concentrations were detected by single chamber analyses. This study demonstrates the potential of using heavy metals anomalies in foraminiferal single chambers as a tool for detecting the industrial footprint of coastal facilities as well as short term events of elevated heavy metals. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. Energy Efficiency in Norway 1996-1999. Monitoring tools for energy efficiency in Europe: the ODYSSEE and MURE projects

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, Eva

    2002-05-01

    This is the national report for Norway in the EU/SAVE project ''Monitoring tools for energy efficiency in Europe: the ODYSSEE and MURE projects''. The report deals with energy use and energy efficiency in Norway 1990-1999. Final energy use per Gross Domestic Product (GDP) was reduced by approximately 1.6% per year from 1990 to 1999. The energy efficiency improvement has been calculated to 0.4% pr year, while the role of structural changes has been 1.2% pr year. A detailed sector analysis has been done, applying Laspeyres indices to attribute changes in energy use to activity, structure or intensity (efficiency). Aggregating sectors, we have found a total efficiency improvement of approximately 8 TWh from 1990 to 1999. (author)

  5. Is monocyte HLA-DR expression monitoring a useful tool to predict the risk of secondary infection?

    Science.gov (United States)

    Lukaszewicz, A-C; Faivre, V; Payen, D

    2010-09-01

    Downregulation of the immune response is common among Intensive Care Unit (ICU) patients after an acute inflammatory injury, whether it was septic or not. Such a modification could be seen as an adaptation to attenuate the effects of the inflammatory storm on tissues, but it exposes the subject to the risk of nosocomial infection and impairs recovery processes. The intensity of immunity downregulation is difficult to characterize, since clinical presentation is silent and non-specific, which urges the use of tools for immune monitoring. This review focuses on the use of monocyte HLA-DR expression to detect immune hyporesponsiveness and to select the appropriate immunomodulating therapy, as well as the efficiency of this technique in controlling secondary infections.

  6. Laser-induced breakdown spectroscopy of dental lesions: diagnostic and therapeutic monitoring tool

    Science.gov (United States)

    Borisova, Ekaterina; Uzunov, Tzonko; Penev, Dimitar; Genova, Tsanislava; Avramov, Latchezar

    2016-01-01

    The carious decay develops a tiny area of demineralization on the enamel, which could be detected by element analytic techniques such as laser-induced breakdown spectroscopy (LIBS). That demineralization can quickly turn into a large lesion inside the tooth, it is often discovered too late to prevent the kind of decay that leads to cavities. The same optical LIBS detection approach could be used for monitoring of the caries removal using laser ablation or drilling techniques. For LIBS measurements we applied LIBS 2500Plus (Ocean Optics Inc., Dunedin, USA) system, which consists of seven spectrometric channels, covering spectral region from 200 to 980 nm, which optical resolution 0,05 nm, the spectrometers are connected with sample fiber bundle for 7-channels spectral system to the chamber for solid and liquid samples, Q-switched Nd:YAG laser, at 1 064 nm, with energy per pulse - 40 mJ, which is applied to induce plasma in the samples. LIBS spectra were obtained after single shot of the laser in the region of pathology. Samples investigated by LIBS are extracted teeth from patients, with periodontal problems on different stage of carious lesions, and their LIBS spectra are compared with the LIBS signals obtained from normal enamel and dentine tissues to receive complete picture of the carious lesion development. The major line of our investigations is related to the development of a methodology for real-time optical feedback control during selective ablation of tooth tissues using LIBS. Tooth structures, with and without pathological changes, are compared and their LIBS element analysis is used to differentiate major changes, which occur during tooth carious process and growth.

  7. Evaluation of mobile smartphones app as a screening tool for environmental noise monitoring.

    Science.gov (United States)

    Ibekwe, Titus S; Folorunsho, David O; Dahilo, Enoch A; Gbujie, Ibeneche O; Nwegbu, Maxwell M; Nwaorgu, Onyekwere G

    2016-01-01

    Noise is a global occupational and environmental health hazard with considerable social and physiological impact and, therefore, there is a need for regular measurements to boost monitoring and regulations of environmental noise levels in our communities. This necessitates a readily available, inexpensive, and easy to use noise measuring device. We aimed to test the sensitivity and validity of mobile "smart" phones for this purpose. This was a comparative analysis of a cross sectional study done between January 2014 and February 2015. Noise levels were measured simultaneously at different locations within Abuja Nigeria at day and night hours in real time environments. A sound level meter (SLM) (Extech407730 Digital Soundmeter, serial no.: 2310135, calibration no: 91037) and three smartphones (Samsung Galaxy note3, Nokia S, and Techno Phantom Z running on Android "Apps" Androidboy1) were used. Statistical calculations were done with Pearson correlation, T-test and Consistency within American National Standards Institute acceptable standard errors. Noise level readings for both daytime and night with the SLM and the mobile phones showed equivalent values. All noise level meters measured were <100dB. The daytime readings were nearly identical in six locations and the maximum difference in values between the SLM and Smartphone instruments was 3db, noted in two locations. Readings in dBA showed strong correlation (r = 0.9) within acceptable error limits for Type 2 SLM devices and no significant difference in the values (p = 0.12 & 0.58) for both day and night. Sensitivity of the instrument yielded 92.9%. The androidboy1 "app" performance in this study showed a good correlation and comparative high sensitivity to the Standard SLM (type 2 SLM device). However there is the need for further studies.

  8. Moving standard deviation and moving sum of outliers as quality tools for monitoring analytical precision.

    Science.gov (United States)

    Liu, Jiakai; Tan, Chin Hon; Badrick, Tony; Loh, Tze Ping

    2018-02-01

    An increase in analytical imprecision (expressed as CV a ) can introduce additional variability (i.e. noise) to the patient results, which poses a challenge to the optimal management of patients. Relatively little work has been done to address the need for continuous monitoring of analytical imprecision. Through numerical simulations, we describe the use of moving standard deviation (movSD) and a recently described moving sum of outlier (movSO) patient results as means for detecting increased analytical imprecision, and compare their performances against internal quality control (QC) and the average of normal (AoN) approaches. The power of detecting an increase in CV a is suboptimal under routine internal QC procedures. The AoN technique almost always had the highest average number of patient results affected before error detection (ANPed), indicating that it had generally the worst capability for detecting an increased CV a . On the other hand, the movSD and movSO approaches were able to detect an increased CV a at significantly lower ANPed, particularly for measurands that displayed a relatively small ratio of biological variation to CV a. CONCLUSION: The movSD and movSO approaches are effective in detecting an increase in CV a for high-risk measurands with small biological variation. Their performance is relatively poor when the biological variation is large. However, the clinical risks of an increase in analytical imprecision is attenuated for these measurands as an increased analytical imprecision will only add marginally to the total variation and less likely to impact on the clinical care. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  9. Power analysis as a tool to identify statistically informative indicators for monitoring coral reef disturbances.

    Science.gov (United States)

    Van Wynsberge, Simon; Gilbert, Antoine; Guillemot, Nicolas; Heintz, Tom; Tremblay-Boyer, Laura

    2017-07-01

    Extensive biological field surveys are costly and time consuming. To optimize sampling and ensure regular monitoring on the long term, identifying informative indicators of anthropogenic disturbances is a priority. In this study, we used 1800 candidate indicators by combining metrics measured from coral, fish, and macro-invertebrate assemblages surveyed from 2006 to 2012 in the vicinity of an ongoing mining project in the Voh-Koné-Pouembout lagoon, New Caledonia. We performed a power analysis to identify a subset of indicators which would best discriminate temporal changes due to a simulated chronic anthropogenic impact. Only 4% of tested indicators were likely to detect a 10% annual decrease of values with sufficient power (>0.80). Corals generally exerted higher statistical power than macro-invertebrates and fishes because of lower natural variability and higher occurrence. For the same reasons, higher taxonomic ranks provided higher power than lower taxonomic ranks. Nevertheless, a number of families of common sedentary or sessile macro-invertebrates and fishes also performed well in detecting changes: Echinometridae, Isognomidae, Muricidae, Tridacninae, Arcidae, and Turbinidae for macro-invertebrates and Pomacentridae, Labridae, and Chaetodontidae for fishes. Interestingly, these families did not provide high power in all geomorphological strata, suggesting that the ability of indicators in detecting anthropogenic impacts was closely linked to reef geomorphology. This study provides a first operational step toward identifying statistically relevant indicators of anthropogenic disturbances in New Caledonia's coral reefs, which can be useful in similar tropical reef ecosystems where little information is available regarding the responses of ecological indicators to anthropogenic disturbances.

  10. cortisol/cortisone ratio as a valid tool of training load monitoring

    Directory of Open Access Journals (Sweden)

    T Bouaziz

    2016-08-01

    Full Text Available The effectiveness of selected physiological and perceptual measures for monitoring training load and fatigue was studied in 16 male elite rugby sevens players during a 6-week intense training block (IT and 2-week tapering (TAP. Daily training load (TL and strain (TS as well as weekly total score of fatigue (TSF were quantified respectively by the session-rating of perceived exertion (RPE method and an 8-item questionnaire. Also, testing was performed and 24 h urinary cortisol (C, cortisone (Cn, adrenaline (A and noradrenalin (NA excretion was measured before (T0 and after the IT (T1 and after the TAP (T2. The TL, TS and TSF increased during the IT and decreased during the TAP, in conjunction with a significant drop and improvement, respectively, of performance standards during the two periods. At T1, C and Cn levels increased while A and NA levels decreased, resulting in a higher C/Cn ratio and lower A/NA ratio, respectively. At T2, both C/Cn and A/NA returned to baseline values. The changes in C/Cn ratio, after the 6-week IT, were more closely related to mean TL, TS and TSF (r=0.75-0.76 vs. r=0.48-0.58, p<0.01 and to changes in the majority of performance measures than to A/NA ratio. Only the changes in C/Cn ratio after the 2-week TAP were related to mean TL, TS and TSF (r=0.61-0.68, p<0.01. The changes in hormone levels, training strain and performance standards reflected the physical and mental stressors of training, with complete recovery, as indicated by physiological homeostasis, achieved after an appropriate tapering period.

  11. Monitoring PAH contamination in water: Comparison of biological and physico-chemical tools

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeault, A., E-mail: bourgeault@ensil.unilim.fr; Gourlay-Francé, C.

    2013-06-01

    The suitability of biological methods and chemical-based passive samplers to determine exposure to PAHs was tested by deploying zebra mussels and SPMDs along the Seine River over 11 months. The concentration of 13 PAHs was analyzed every month in both water and mussels. The sum of the PAH concentrations in mussels, initially at 299 ng g{sub dry} {sub wt}{sup −1}, reached 2654, 3972 and 3727 ng g{sup −1} at the end of exposure in the three sampling points taken through the river. The respective SPMD-available concentrations of TPAHs reached 9, 52 and 34 ng L{sup −1}. Results showed seasonal variations of total PAH concentrations in the mussels, characterized by a decrease during spawning. The non-achievement of steady state concentration that was observed in mussels may be accounted for by the temporal variation of environmental concentrations. Thus, a bioaccumulation model based on kinetic rather than simple equilibrium partitioning was found to be more appropriate to describe PAH content in mussels. Moreover, biodynamic kinetic modeling proved useful to better understand the uptake and loss processes of pyrene. It clearly shows that these processes are markedly influenced by the biological state of the zebra mussels. The most realistic hypothesis is that the temporal variation of the biodynamic parameters may originate from a decrease of the mussels' metabolization of PAHs during spawning. Since SPMD passive samplers cannot integrate such biological factors, they are poor predictors of PAH bioavailability in mussels. - Highlights: • PAH contamination was monitored by deploying mussels and SPMDs over 11 months along the Seine River. • 5–6 ring PAHs which could not be quantified in spot samples, were measured in SPMDs. • PAH concentrations in the mussels decreased during spawning. • Temporal variation of bioaccumulated PAH may originate from a decrease of the mussels' metabolism during spawning. • Biodynamic model was allowed to explain

  12. Monitoring PAH contamination in water: Comparison of biological and physico-chemical tools

    International Nuclear Information System (INIS)

    Bourgeault, A.; Gourlay-Francé, C.

    2013-01-01

    The suitability of biological methods and chemical-based passive samplers to determine exposure to PAHs was tested by deploying zebra mussels and SPMDs along the Seine River over 11 months. The concentration of 13 PAHs was analyzed every month in both water and mussels. The sum of the PAH concentrations in mussels, initially at 299 ng g dry wt −1 , reached 2654, 3972 and 3727 ng g −1 at the end of exposure in the three sampling points taken through the river. The respective SPMD-available concentrations of TPAHs reached 9, 52 and 34 ng L −1 . Results showed seasonal variations of total PAH concentrations in the mussels, characterized by a decrease during spawning. The non-achievement of steady state concentration that was observed in mussels may be accounted for by the temporal variation of environmental concentrations. Thus, a bioaccumulation model based on kinetic rather than simple equilibrium partitioning was found to be more appropriate to describe PAH content in mussels. Moreover, biodynamic kinetic modeling proved useful to better understand the uptake and loss processes of pyrene. It clearly shows that these processes are markedly influenced by the biological state of the zebra mussels. The most realistic hypothesis is that the temporal variation of the biodynamic parameters may originate from a decrease of the mussels' metabolization of PAHs during spawning. Since SPMD passive samplers cannot integrate such biological factors, they are poor predictors of PAH bioavailability in mussels. - Highlights: • PAH contamination was monitored by deploying mussels and SPMDs over 11 months along the Seine River. • 5–6 ring PAHs which could not be quantified in spot samples, were measured in SPMDs. • PAH concentrations in the mussels decreased during spawning. • Temporal variation of bioaccumulated PAH may originate from a decrease of the mussels' metabolism during spawning. • Biodynamic model was allowed to explain the bioaccumulation

  13. Low-Frequency Electrochemical Impedance Spectroscopy as a Monitoring Tool for Yeast Growth in Industrial Brewing Processes

    Directory of Open Access Journals (Sweden)

    Christoph Slouka

    2017-08-01

    Full Text Available Today’s yeast total biomass and viability measurements during the brewing process are dependent on offline methods such as methylene blue or florescence dye-based staining, and/or the usage of flow cytometric measurements. Additionally, microscopic cell counting methods decelerate an easy and quick prediction of yeast viability. These processes are time consuming and result in a time-delayed response signal, which not only reduces the knowledge of the performance of the yeast itself, but also impacts the quality of the final product. Novel approaches in process monitoring during the aerobic and anaerobic fermentation of Saccharomyces cerevisiae are not only limited to classical pH, dO2 and off-gas analysis, but they also use different in situ and online sensors based on different physical principles to determine the biomass, product quality and cell death. Within this contribution, electrochemical impedance spectroscopy (EIS was used to monitor the biomass produced in aerobic and anaerobic batch cultivation approaches, simulating the propagation and fermentation unit operation of industrial brewing processes. Increases in the double-layer capacitance (CDL, determined at frequencies below 1 kHz, were proportional to the increase of biomass in the batch, which was monitored in the online and inline mode. A good correlation of CDL with the cell density was found. In order to prove the robustness and flexibility of this novel method, different state-of-the-art biomass measurements (dry cell weight—DCW and optical density—OD were performed for comparison. Because measurements in this frequency range are largely determined by the double-layer region between the electrode and media, rather minor interferences with process parameters (aeration and stirring were to be expected. It is shown that impedance spectroscopy at low frequencies is not only a powerful tool for the monitoring of viable yeast cell concentrations during operation, but it is

  14. [An ongoing twin pregnancy after embryo time laps monitoring in a patient with a history of IVF failures--case report and literature review].

    Science.gov (United States)

    Radwan, Paweł; Krasiński, Rafał; Radwan, Michał; Połać, Ireneusz

    2014-04-01

    A standard assessment of embryo morphology at given time points does not always allow to transfer the embryo with the highest implantation potential. The effect of transfer of an improper embryo results in a lack of pregnancy or a miscarriage and, as a consequence, exposes the patient to unnecessary emotional stress and necessity to perform yet another transfer of frozen embryos. We present a case of a patient with earlier IVF failures. The use of time-lapse technique in this case helped to choose two good embryos. The transfer resulted in ongoing twin pregnancy. A 35-year-old woman with history of IVF-ET treatment failure was deemed eligible for an ICSI procedure because of the male factor. Ovarian stimulation was performed according to the agonist long protocol. Eight MII oocytes were fertilized and seven embryos were obtained. Continuous embryo monitoring was performed with the use of Primo Vision system. Forty-four hours after fertilization only 2 correctly developing embryos were identified. They were transferred on day 3. The development of the remaining 5 embryos was arrested. These embryos did not achieve the blastocyst stage on day 5-6 after fertilization. Forty days after embryo transfer a twin pregnancy, confirmed with fetal heart rate of both fetuses, was revealed on ultrasound examination. Currently the patient is at 27 weeks of ongoing twin gestation. The system of continuous embryo monitoring introduces new criteria for the examination of embryo development. These new parameters can be useful in clinical practice. However prospective randomized studies are necessary to provide data confirming the usefulness of time-lapse technique in IVF treatment.

  15. Bacteriophage removal efficiency as a validation and operational monitoring tool for virus reduction in wastewater reclamation: Review.

    Science.gov (United States)

    Amarasiri, Mohan; Kitajima, Masaaki; Nguyen, Thanh H; Okabe, Satoshi; Sano, Daisuke

    2017-09-15

    The multiple-barrier concept is widely employed in international and domestic guidelines for wastewater reclamation and reuse for microbiological risk management, in which a wastewater reclamation system is designed to achieve guideline values of the performance target of microbe reduction. Enteric viruses are one of the pathogens for which the target reduction values are stipulated in guidelines, but frequent monitoring to validate human virus removal efficacy is challenging in a daily operation due to the cumbersome procedures for virus quantification in wastewater. Bacteriophages have been the first choice surrogate for this task, because of the well-characterized nature of strains and the presence of established protocols for quantification. Here, we performed a meta-analysis to calculate the average log 10 reduction values (LRVs) of somatic coliphages, F-specific phages, MS2 coliphage and T4 phage by membrane bioreactor, activated sludge, constructed wetlands, pond systems, microfiltration and ultrafiltration. The calculated LRVs of bacteriophages were then compared with reported human enteric virus LRVs. MS2 coliphage LRVs in MBR processes were shown to be lower than those of norovirus GII and enterovirus, suggesting it as a possible validation and operational monitoring tool. The other bacteriophages provided higher LRVs compared to human viruses. The data sets on LRVs of human viruses and bacteriophages are scarce except for MBR and conventional activated sludge processes, which highlights the necessity of investigating LRVs of human viruses and bacteriophages in multiple treatment unit processes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Biological and biochemical soil indicators: monitoring tools of different agricultural managements

    Science.gov (United States)

    Scotti, Riccardo; Sultana, Salma; Scelza, Rosalia; Marzaioli, Rossana; D'Ascoli, Rosaria; Rao, Maria A.

    2010-05-01

    The intensive agricultural managements, increased in the last twenty years, have resulted in a decrease in fertility of soils, representing a serious threat to agricultural productivity due to both the increase in production cost, mainly for intensive use of mineral fertilizers, and the loss of the quality of crops themselves. Organic matter content is closely related to the soil fertility and its progressive reduction in cultivates soils, without a satisfactory recovery, could make agriculture untenable, resulting in a high detrimental effect on environment. But an appropriate soil management practices can improve soil quality by utilizing organic amendments as alternative to mineral fertilizers to increase soil quality and plant growth. In this context, demand of suitable indicators, whose are able to assess the impact of different agricultural managements on soil quality, has increased. It has shown that soil biological and biochemical properties are able to respond to small changes in soil conditions, thus providing information on subtle alterations in soil quality. Aim of this study was to evaluate the use of soil biological and biochemical properties as fertility indicators in agricultural soils under different agricultural managements, sited in Campania Region (Southern Italy). After a preliminary monitoring phase of soil fertility on different farms sited in five agricultural areas of Campania Region, we have selected two farms in two different study areas to assess the effect on soil quality of different organic amendments. In particular, a compost from municipal solid waste and wood from scraps of poplars pruning were supplied in different doses and ratios. Soil samplings after one month from the amendment addition and then every 4 months until a year were carried out. All collected soil samples were characterized by main physical, chemical, biochemical and biological properties. In general, the use of different organic amendments showed a positive effect

  17. Development of Tools and Techniques to Survey, Assess, Stabilise, Monitor and Preserve Underwater Archaeological Sites: SASMAP

    Science.gov (United States)

    Gregory, D. J.

    2015-08-01

    SASMAP's purpose is to develop new technologies and best practices in order to locate, assess and manage Europe's underwater cultural heritage in a more effective way than is possible today. SASMAP has taken an holistic- and process- based approach to investigating underwater environments and the archaeological sites contained therein. End user of the results of SASMAP are severalfold; i) to benefiet the SMEs involved in the project and development of their products for the offshore industry (not just for archaeological purposes) ii) a better understanding of the marine environment and its effect on archaeological materials iii) the collation of the results from the project into guidelines that can be used by cultural resource managers to better administer and optimise developer lead underwater archaeological project within Europe in accordance with European legislation (Treaty of Valetta (1992). Summarily the project has utilised a down scaling approach to localise archaeological sites at a large scale regional level. This has involved using innovative satellite imagery to obtain seamless topography maps over coastal areas and the seabed (accurate to a depth of 6m) as well as the development of a 3D sub bottom profiler to look within the seabed. Results obtained from the downscaling approach at the study areas in the project (Greece and Denmark) have enabled geological models to be developed inorder to work towards predictive modelling of where submerged prehistoric sites may be encountered. Once sites have been located an upscaling approach has been taken to assessing an individual site and the materials on and within it in order to better understand the state of preservation and dynamic conditions of a site and how it can best be preserved through in situ preservation or excavation. This has involved the development of equipment to monitor the seabed environment (open water and in sediments), equipment for sampling sediments and assessing the state of

  18. Damage tolerant design and condition monitoring of composite material and bondlines in wind turbine blades: Failure and crack propagation

    DEFF Research Database (Denmark)

    Pereira, Gilmar Ferreira; Mikkelsen, Lars Pilgaard; McGugan, Malcolm

    2015-01-01

    This research presents a novel method to asses a crack growing/damage event in composite material, in polymer, or in structural adhesive using Fibre Bragg Grating (FBG) sensors embedded in the host material, and its application in to a composite material structure: Wind Turbine Trailing Edge....... A Structure-Material-Sensor Finite Element Method (FEM) model was developed to simulate the Fibre Bragg Grating sensor output response, when embedded in a host material (Composite material, polymer or adhesive), during a crack growing/damage event. This Structure-Material-Sensor model provides a tool...

  19. Post-exercise contractility, diastolic function, and pressure: Operator-independent sensor-based intelligent monitoring for heart failure telemedicine

    Directory of Open Access Journals (Sweden)

    Giannoni Massimo

    2009-05-01

    Full Text Available Abstract Background New sensors for intelligent remote monitoring of the heart should be developed. Recently, a cutaneous force-frequency relation recording system has been validated based on heart sound amplitude and timing variations at increasing heart rates. Aim To assess sensor-based post-exercise contractility, diastolic function and pressure in normal and diseased hearts as a model of a wireless telemedicine system. Methods We enrolled 150 patients and 22 controls referred for exercise-stress echocardiography, age 55 ± 18 years. The sensor was attached in the precordial region by an ECG electrode. Stress and recovery contractility were derived by first heart sound amplitude vibration changes; diastolic times were acquired continuously. Systemic pressure changes were quantitatively documented by second heart sound recording. Results Interpretable sensor recordings were obtained in all patients (feasibility = 100%. Post-exercise contractility overshoot (defined as increase > 10% of recovery contractility vs exercise value was more frequent in patients than controls (27% vs 8%, p 1 in 20 patients and in none of the controls (p 1 in only 3 patients (p Conclusion Post-exercise contractility, diastolic time and pressure changes can be continuously measured by a cutaneous sensor. Heart disease affects not only exercise systolic performance, but also post-exercise recovery, diastolic time intervals and blood pressure changes – in our study, all of these were monitored by a non-invasive wearable sensor.

  20. Management Information System (MIS: Tool for Monitoring the Waste Management Health Service (RSS and Cost of Treatment

    Directory of Open Access Journals (Sweden)

    Vania Elisabete Schneider

    2013-06-01

    Full Text Available One of the major challenges of solid waste management has been improve and deploy systems that perform monitoring and control of management processes of health service’s waste (HSW. This study aims to evaluate the total cost per category of HSW/day and active bed/day with the handling of HSW in a teaching hospital in northeastern area of Brazil`s Rio Grande do Sul state and identify contributions of a management information system (MIS in the management process, especially considering the generation and segregation of waste. Utilized methodology was developed in two stages: data collection about the management of the HSW and proposition, implementation and feed of a MIS for recording and processing of data related to waste characterization. Results show that whether the management system of the hospital in this study were 100% right, the monthly savings for the treatment of infectious waste would be 18.4% of the costs and 5.83% of costs of chemical waste. The implementation of MIS becomes an essential tool in the evaluation of the management process of HSW since it makes possible to raise issues of fundamental importance to the implementation and evaluation of strategies contained in the HSW management plan. The MIS also represents a tool of easy reference and of great importance to evaluate generation of HSW as it helps to promote the surveillance, identification of sectors that have the biggest problems with segregation, as well as ways to minimize costs and impacts.

  1. Detection of UV-treatment effects on plankton by rapid analytic tools for ballast water compliance monitoring immediately following treatment

    Science.gov (United States)

    Bradie, Johanna; Gianoli, Claudio; He, Jianjun; Lo Curto, Alberto; Stehouwer, Peter; Veldhuis, Marcel; Welschmeyer, Nick; Younan, Lawrence; Zaake, André; Bailey, Sarah

    2018-03-01

    Non-indigenous species seriously threaten native biodiversity. To reduce establishments, the International Maritime Organization established the Convention for the Control and Management of Ships' Ballast Water and Sediments which limits organism concentrations at discharge under regulation D-2. Most ships will comply by using on-board treatment systems to disinfect their ballast water. Port state control officers will need simple, rapid methods to detect compliance. Appropriate monitoring methods may be dependent on treatment type, since different treatments will affect organisms by a variety of mechanisms. Many indicative tools have been developed, but must be examined to ensure the measured variable is an appropriate signal for the response of the organisms to the applied treatment. We assessed the abilities of multiple analytic tools to rapidly detect the effects of a ballast water treatment system based on UV disinfection. All devices detected a large decrease in the concentrations of vital organisms ≥ 50 μm and organisms organisms, as examined herein for UV-C treatment systems.

  2. Assessment of the global trigger tool to measure, monitor and evaluate patient safety in cancer patients: reliability concerns are raised.

    Science.gov (United States)

    Mattsson, Thea Otto; Knudsen, Janne Lehmann; Lauritsen, Jens; Brixen, Kim; Herrstedt, Jørn

    2013-07-01

    Countries around the world are currently aiming to improve patient safety by means of the Institute for Healthcare Improvement global trigger tool (GTT), which is considered a valid tool for evaluating and measuring patient safety within organisations. So far, only few data on the measurement properties and utility of the GTT have been published. To determine and evaluate the effect of interrater variation between review teams on the standard outcome measures of the GTT and to assess and quantify measurement error of the GTT. Retrospective chart reviews were conducted on identical charts by two independent review teams in 2010 at a department of oncology in a university hospital. Standard GTT outcome measurements were obtained and compared between teams using statistical process control (SPC) charts. A Bland-Altman plot assessed measurement error and limits of agreement. Only 31% of adverse events (AE) were identified by both teams, and further differences in categorisation of identical events was found. Moderate interrater agreement (κ=0.45) between teams gave rise to different conclusions on the patient safety process when monitoring using SPC charts. The Bland-Altman plot suggests little systematic error but large random error. Review teams may identify different AE and reach different conclusions on the safety process when using the GTT on identical charts. Tracking true change in the safety level is difficult due to measurement error of the GTT. The results do not encourage further use of the GTT until additional evaluation studies on the measurement properties of the GTT have been conducted.

  3. Flood Foresight: A near-real time flood monitoring and forecasting tool for rapid and predictive flood impact assessment

    Science.gov (United States)

    Revilla-Romero, Beatriz; Shelton, Kay; Wood, Elizabeth; Berry, Robert; Bevington, John; Hankin, Barry; Lewis, Gavin; Gubbin, Andrew; Griffiths, Samuel; Barnard, Paul; Pinnell, Marc; Huyck, Charles

    2017-04-01

    -scale view of the extent and depth of possible riverine flood events several days in advance by linking forecast river flow from a hydrological model to a global flood risk map. The Monitoring component provides a similar local-scale view of a flood inundation extent but in near real time, as an event unfolds, by combining the global flood risk map with observed river gauge telemetry. Immediately following an event, the maximum extent of the flood is also generated. Users of Flood Foresight will be able to receive current and forecast flood extents and depth information via API into their own GIS or analytics software. The set of tools is currently operational for the UK and Europe; the methods presented can be applied globally, allowing provision of service to any country or region. This project was supported by InnovateUK under the Solving Business Problems with Environmental Data competition.

  4. SURFACE GEOPHYSICAL EXPLORATION DEVELOPING NONINVASIVE TOOLS TO MONITOR PAST LEAKS AROUND HANFORD TANK FARMS

    Energy Technology Data Exchange (ETDEWEB)

    MYERS DA; RUCKER DF; LEVITT MT; CUBBAGE B; NOONAN GE; MCNEILL M; HENDERSON C

    2011-06-17

    A characterization program has been developed at Hanford to image past leaks in and around the underground storage tank facilities. The program is based on electrical resistivity, a geophysical technique that maps the distribution of electrical properties of the subsurface. The method was shown to be immediately successful in open areas devoid of underground metallic infrastructure, due to the large contrast in material properties between the highly saline waste and the dry sandy host environment. The results in these areas, confirmed by a limited number of boreholes, demonstrate a tendency for the lateral extent of the underground waste plume to remain within the approximate footprint of the disposal facility. In infrastructure-rich areas, such as tank farms, the conventional application of electrical resistivity using small point-source surface electrodes initially presented a challenge for the resistivity method. The method was then adapted to directly use the buried infrastructure as electrodes for both transmission of electrical current and measurements of voltage. For example, steel-cased wells that surround the tanks were used as long electrodes, which helped to avoid much of the infrastructure problems. Overcoming the drawbacks of the long electrode method has been the focus of our work over the past seven years. The drawbacks include low vertical resolution and limited lateral coverage. The lateral coverage issue has been improved by supplementing the long electrodes with surface electrodes in areas devoid of infrastructure. The vertical resolution has been increased by developing borehole electrode arrays that can fit within the small-diameter drive casing of a direct push rig. The evolution of the program has led to some exceptional advances in the application of geophysical methods, including logistical deployment of the technology in hazardous areas, development of parallel processing resistivity inversion algorithms, and adapting the processing tools

  5. Evaluating detection and monitoring tools for incipient and relictual non-native ungulate populations

    Science.gov (United States)

    Judge, Seth W.; Hess, Steve; Faford, Jonathan K.J.; Pacheco, Dexter; Leopold, Christina R.; Cole, Colleen; Deguzman, Veronica

    2016-01-01

    Hawai‘i Volcanoes National Park (HAVO) encompasses 1,308 km2 on Hawai‘i Island. The park harbors endemic plants and animals which are threatened by a variety of invasive species. Introduced ungulates have caused sharp declines of numerous endemic species and have converted ecosystems to novel grazing systems in many cases. Local ranchers and the Territorial Government of Hawai‘i had long conducted regional ungulate control even prior to the establishment of HAVO in 1916. In 1995 the park’s hunting team began a new hunt database that allowed managers to review hunt effort and effectiveness in each management unit. Target species included feral pigs (Sus scrofa), European mouflon sheep (Ovis gmelini musimon), feral goats (Capra hircus) and wild cattle (Bos taurus). Hunters removed 1,204 feral pigs from HAVO over a 19-year period (1996‒2014). A variety of methods were employed, but trapping, snaring and ground hunts with dogs accounted for the most kills. Trapping yielded the most animals per unit effort. Hunters and volunteers removed 6,657 mouflon from HAVO; 6,601 of those were from the 468 km2 Kahuku Unit. Aerial hunts yielded the most animals followed by ground hunt methods. Hunters completed eradications of goats in several management units over an 18- year period (1997‒2014) when they removed the last 239 known individuals in HAVO primarily with aerial hunts. There have also been seven cattle and five feral dogs (Canis familiaris) removed from HAVO. Establishing benchmarks and monitoring the success of on-the-ground ungulate removal efforts can improve the efficiency of protecting and restoring native forest for high-priority watersheds and native wildlife. We tested a variety of methods to detect small populations of ungulates within HAVO and the Hō‘ili Wai study area in the high-priority watershed of Ka‘ū Forest Reserve on Hawai‘i Island. We conducted ground surveys, aerial surveys and continuous camera trap monitoring in both fence

  6. Use of a real time continuous glucose monitoring system as an educational tool for patients with gestational diabetes.

    Science.gov (United States)

    Alfadhli, Eman; Osman, Eman; Basri, Taghreed

    2016-01-01

    Women with gestational diabetes mellitus (GDM) are required to control their blood glucose shortly after GDM diagnosis to minimize adverse pregnancy outcomes. A real time-continuous glucose monitoring system (RT-CGMS) provides the patient with continuous information about the alterations in levels of the blood glucose. This visibility may empower the patient to modify her lifestyle and engage in therapeutic management. The aim of this study was to determine whether a single application of RT-CGMS to pregnant women shortly after GDM diagnosis is useful as an educational and motivational tool. This study was a prospective open label randomized controlled study conducted at Maternity and Children Hospital, Medina, Saudi Arabia. A total of 130 pregnant women with GDM were randomised to either blood glucose self-monitor alone (SMBG group) (n = 62) or in addition to SMBG, patients wore a Guardian(®) REAL-Time Continuous Glucose Monitoring System (Medtronic MiniMed) once for 3-7 days, within 2 weeks of GDM diagnosis (RT-CGMS group) (n = 68). The primary outcomes were maternal glycemic control and pregnancy outcomes. Secondary outcomes were the changes in parameters of glucose variability, which includes mean sensor readings, standard deviation (SD) of blood glucose, and area under the curve for hyper and hypoglycaemia at the end of the RT-CGMS application. HbA1c, mean fasting and postprandial glucose levels were similar in both groups at the end of the pregnancy. Pregnancy outcomes were comparable. However, there was significant improvement in the parameters of glucose variability on the last day of sensor application; both mean glucose and the SD of mean glycaemia were reduced significantly; P = 0.016 and P = 0.034, respectively. The area under the curve for hyper and hypoglycaemia were improved, however, the results were not statistically significant. Although a single application of RT-CGMS shortly after GDM diagnosis is helpful as an educational tool, it

  7. Acoustic Emission Monitoring of Incipient Failure in Journal Bearings( III ) - Development of AE Diagnosis System for Journal Bearings -

    International Nuclear Information System (INIS)

    Chung, Min Hwa; Cho, Yong Sang; Yoon, Dong Jin; Kwon, Oh Yang

    1996-01-01

    For the condition monitoring of the journal bearing in rotating machinery, a system for their diagnosis by acoustic emission(AE) was developed. AE has been used to detect abnormal conditions in the bearing system. It was found from the field application study as well as the laboratory experiment using a simulated journal bearing system that AE RMS voltage was the most efficient parameter for the purpose of current study. Based on the above results, algorithms and judgement criteria for the diagnosis system was established. The system is composed of four parts as follows: the sensing part including AE sensor and preamplifier, the signal processing part for RMS-to-DC conversion to measure AE ms voltage, the interface part for transferring RMS voltage data into PC using A/D converter, and the software part including the graphic display of bearing conditions and the diagnosis program

  8. Preliminary Development of Real Time Usage-Phase Monitoring System for CNC Machine Tools with a Case Study on CNC Machine VMC 250

    Science.gov (United States)

    Budi Harja, Herman; Prakosa, Tri; Raharno, Sri; Yuwana Martawirya, Yatna; Nurhadi, Indra; Setyo Nogroho, Alamsyah

    2018-03-01

    The production characteristic of job-shop industry at which products have wide variety but small amounts causes every machine tool will be shared to conduct production process with dynamic load. Its dynamic condition operation directly affects machine tools component reliability. Hence, determination of maintenance schedule for every component should be calculated based on actual usage of machine tools component. This paper describes study on development of monitoring system to obtaining information about each CNC machine tool component usage in real time approached by component grouping based on its operation phase. A special device has been developed for monitoring machine tool component usage by utilizing usage phase activity data taken from certain electronics components within CNC machine. The components are adaptor, servo driver and spindle driver, as well as some additional components such as microcontroller and relays. The obtained data are utilized for detecting machine utilization phases such as power on state, machine ready state or spindle running state. Experimental result have shown that the developed CNC machine tool monitoring system is capable of obtaining phase information of machine tool usage as well as its duration and displays the information at the user interface application.

  9. Imaging assessment of a portable hemodialysis device: detection of possible failure modes and monitoring of functional performance.

    Science.gov (United States)

    Olorunsola, Olufoladare G; Kim, Steven H; Chang, Ryan; Kuo, Yuo-Chen; Hetts, Steven W; Heller, Alex; Kant, Rishi; Saeed, Maythem; Fissell, William H; Roy, Shuvo; Wilson, Mark W

    2014-03-27

    The purpose of this study was to investigate the utility and limitations of various imaging modalities in the noninvasive assessment of a novel compact hemodialyzer under development for renal replacement therapy, with specific aim towards monitoring its functional performance. The prototype is a 4×3×6 cm aluminum cartridge housing "blood" and "dialysate" flow paths arranged in parallel. A sheet of semipermeable silicon nanopore membranes forms the blood-dialysate interface, allowing passage of small molecules. Blood flow was simulated using a peristaltic pump to instill iodinated contrast through the blood compartment, while de-ionized water was instilled through the dialysate compartment at a matched rate in the countercurrent direction. Images were acquired under these flow conditions using multi-detector computed tomography (MDCT), fluoroscopy, high-resolution quantitative computed tomography (HR-QCT), and magnetic resonance imaging (MRI). MDCT was used to monitor contrast diffusion efficiency by plotting contrast density as a function of position along the path of flow through the cartridge during steady state infusion at 1 and 20 mL/min. Both linear and exponential regressions were used to model contrast decay along the flow path. Both linear and exponential models of contrast decay appeared to be reasonable approximations, yielding similar results for contrast diffusion during a single pass through the cartridge. There was no measurable difference in contrast diffusion when comparing 1 mL/min and 20 mL/min flow rates. Fluoroscopy allowed a gross qualitative assessment of flow within the device, and revealed flow inhomogeneity within the corner of the cartridge opposite the blood inlet port. MRI and HR-QCT were both severely limited due to the paramagnetic properties and high atomic number of the target material, respectively. During testing, we encountered several causes of device malfunction, including leak formation, trapped gas, and contrast

  10. Diabetes Mellitus, Microalbuminuria, and Subclinical Cardiac Disease: Identification and Monitoring of Individuals at Risk of Heart Failure.

    Science.gov (United States)

    Swoboda, Peter P; McDiarmid, Adam K; Erhayiem, Bara; Ripley, David P; Dobson, Laura E; Garg, Pankaj; Musa, Tarique A; Witte, Klaus K; Kearney, Mark T; Barth, Julian H; Ajjan, Ramzi; Greenwood, John P; Plein, Sven

    2017-07-17

    Patients with type 2 diabetes mellitus and elevated urinary albumin:creatinine ratio (ACR) have increased risk of heart failure. We hypothesized this was because of cardiac tissue changes rather than silent coronary artery disease. In a case-controlled observational study 130 subjects including 50 ACR+ve diabetes mellitus patients with persistent microalbuminuria (ACR >2.5 mg/mol in males and >3.5 mg/mol in females, ≥2 measurements, no previous renin-angiotensin-aldosterone therapy, 50 ACR-ve diabetes mellitus patients and 30 controls underwent cardiovascular magnetic resonance for investigation of myocardial fibrosis, ischemia and infarction, and echocardiography. Thirty ACR+ve patients underwent further testing after 1-year treatment with renin-angiotensin-aldosterone blockade. Cardiac extracellular volume fraction, a measure of diffuse fibrosis, was higher in diabetes mellitus patients than controls (26.1±3.4% and 23.3±3.0% P =0.0002) and in ACR+ve than ACR-ve diabetes mellitus patients (27.2±4.1% versus 25.1±2.9%, P =0.004). ACR+ve patients also had lower E' measured by echocardiography (8.2±1.9 cm/s versus 8.9±1.9 cm/s, P =0.04) and elevated high-sensitivity cardiac troponin T 18% versus 4% ≥14 ng/L ( P =0.05). Rate of silent myocardial ischemia or infarction were not influenced by ACR status. Renin-angiotensin-aldosterone blockade was associated with increased left ventricular ejection fraction (59.3±7.8 to 61.5±8.7%, P =0.03) and decreased extracellular volume fraction (26.5±3.6 to 25.2±3.1, P =0.01) but no changes in diastolic function or high-sensitivity cardiac troponin T levels. Asymptomatic diabetes mellitus patients with persistent microalbuminuria have markers of diffuse cardiac fibrosis including elevated extracellular volume fraction, high-sensitivity cardiac troponin T, and diastolic dysfunction, which may in part be reversible by renin-angiotensin-aldosterone blockade. Increased risk in these patients may be mediated by

  11. Value of Telemonitoring and Telemedicine in Heart Failure Management

    Science.gov (United States)

    Alderighi, Camilla; Rasoini, Raffaele; Mazzanti, Marco; Casolo, Giancarlo

    2017-01-01

    The use of telemonitoring and telemedicine is a relatively new but quickly developing area in medicine. As new digital tools and applications are being created and used to manage medical conditions such as heart failure, many implications require close consideration and further study, including the effectiveness and safety of these telemonitoring tools in diagnosing, treating and managing heart failure compared to traditional face-to-face doctor–patient interaction. When compared to multidisciplinary intervention programs which are frequently hindered by economic, geographic and bureaucratic barriers, non-invasive remote monitoring could be a solution to support and promote the care of patients over time. Therefore it is crucial to identify the most relevant biological parameters to monitor, which heart failure sub-populations may gain real benefits from telehealth interventions and in which specific healthcare subsets these interventions should be implemented in order to maximise value. PMID:29387464

  12. State of the Art and Trends in the Monitoring, Detection and Diagnosis of Failures in Electric Induction Motors

    Directory of Open Access Journals (Sweden)

    Yuri Merizalde

    2017-07-01

    Full Text Available Despite the complex mathematical models and physical phenomena on which it is based, the simplicity of its construction, its affordability, the versatility of its applications and the relative ease of its control have made the electric induction motor an essential element in a considerable number of processes at the industrial and domestic levels, in which it converts electrical energy into mechanical energy. The importance of this type of machine for the continuity of operation, mainly in industry, is such that, in addition to being an important part of the study programs of careers related to this branch of electrical engineering, a large number of investigations into monitoring, detecting and quickly diagnosing its incipient faults due to a variety of factors have been conducted. This bibliographic research aims to analyze the conceptual aspects of the first discoveries that served as the basis for the invention of the induction motor, ranging from the development of the Fourier series, the Fourier transform mathematical formula in its different forms and the measurement, treatment and analysis of signals to techniques based on artificial intelligence and soft computing. This research also includes topics of interest such as fault types and their classification according to the engine, software and hardware parts used and modern approaches or maintenance strategies.

  13. Research on RCP400-TB50 type reactor coolant pump shaft seal failure analysis and monitoring method

    International Nuclear Information System (INIS)

    Yuan Chaolian; Shen Yuxian; Wang Chuan; Du Pengcheng

    2014-01-01

    Mechanical seal is widely applied in mechanical devices of nuclear power plant. 3-stages mechanical seal applied in reactor coolant pump (abbreviate to RCP) is a kind of product with top technology and manufacture difficulty. As the only running machine in primary loop of nuclear power plant, RCP is designed with high security, reliability and perform ability. So performance of its key component, 3-stages mechanical seal, could directly decide whether units can operate safely and reliably. In this paper mechanical seal used in RCP400-TB50 type RCP which in designed and manufactured by Andritz AG is selected as a typical example of dynamic pressure type mechanical seal applied in second generation NPP. Its structure and working principle is expounded. Engineering fluid mechanics theory is used to establish the mathematical model using for analyzing status of mechanical seal and deducing the theoretical formula. Its correctness is verified by compare with the test data. So that research result can be used as the theoretical basis for analysis of RCP400-TB50 RCP shaft seal's working condition. According to the shaft seal operation characteristic we can establish a suitable RCP shaft seal monitoring method and interlock protection setting for NPP operation. (authors)

  14. Monitoring of ventilation during the early part of cardiopulmonary exercise testing: the first step to detect central sleep apnoea in chronic heart failure.

    Science.gov (United States)

    Roche, Frédéric; Maudoux, Delphine; Jamon, Yann; Barthelemy, Jean-Claude

    2008-05-01

    To evaluate the prediction of nocturnal central sleep apnoea (CSA) syndrome from the presence of periodic breathing (PB) on diurnal monitoring of pre-exercise (cardiopulmonary exercise test [CPX]) parameters. CSA syndrome is commonly found in congestive heart failure (CHF) patients and has several prognostic and therapeutic implications but is frequently undiagnosed. Awake PB pattern is sometimes observed during the CPX cardiopulmonary monitoring period of gas exchanges in CHF patients referred to the stress test laboratory for routine peak VO2 determination. Forty-five consecutive ambulatory patients (2 women/43 men; 60.2+/-11.7 years old) with clinically moderate to severe CHF (New York Heart Association [NYHA] class II/III: 22/23; mean+/-standard deviation left ventricular ejection fraction [LVEF]: 30.5+/-6.6%) underwent a classical maximal CPX test including a 2-min period (pre-test) of gas exchange monitoring and nocturnal ambulatory polygraphic monitoring. PB was defined when a cyclical pattern of VE, VO2, VCO2, was visually noted during the pre-exercise period and/or during the first 4 min of the CPX. CSA syndrome was retained as a central apnoea-plus-hypopnea index (cAHI) equal to or more than 10/h. The sleep study scoring procedure was done independently of the knowledge of the CPX results. Sensitivity, specificity and predictive values were calculated and receiver operating characteristic (ROC) curve analysis was constructed. Peak VO2 reached 16.4+/-5.2 mL kg(-1)min(-1) (55% of the theoretical value adjusted for gender and age). The polygraphy was completed and validated (at least five consecutive hours of sleep) in all cases. CSA syndrome was found in 28 (62%) patients (mean cAHI: 19.3+/-8.6/h). Sensitivity for the prediction of CSA syndrome reached 92.9% (two false-negative patients with a cAHI of nine) and specificity 94.1% with a predictive accuracy of 93.3%. The only false-positive patient suffered a moderate but significant obstructive sleep apnoea

  15. Failure Assessment

    Science.gov (United States)

    Lutz, Robyn; Nikora, Allen

    2005-01-01

    Three questions to which software developers want accurate, precise answers are "How can the software system fail?", "mat bad things will happen if the software fails?t', and "How many failures will the software experience?". Numerous techniques have been devised to answer these questions; three of the best known are: 1) Software Fault Tree Analysis (SFTA) 2) Software Failure Modes, Effects, and Criticality Analysis (SFMECA 3) Software Fault/Failure Modeling. SFTA and SFMECA have been successfully used to analyze the flight software for a number of robotic planetary exploration missions, including Galileo, Cassini, and Deep Space 1. Given the increasing interest in reusing software components from mission to mission, one of us has developed techniques for reusing the corresponding portions of the SFTA and SFMECA, reducing the effort required to conduct these analyses. SFTA has also been shown to be effective in analyzing the security aspects of software systems; intrusion mechanisms and effects can easily be modeled using these techniques. The Bi- Directional Safety Analysis (BDSA) method combines a forward search (similar to SFMECA) from potential failure modes to their effects, with a backward search (similar to SFTA) from feasible hazards to the contributing causes of each hazard. BDSA offers an efficient way to identify latent failures. Recent work has extended BDSA to product-line applications such as flight-instrumentation displays and developed tool support for the reuse of the failure-analysis artifacts within a product line. BDSA has also been streamlined to support those projects having tight cost and/or schedule constraints for their failure analysis efforts. We discuss lessons learned from practice, describe available tools, and identi@ some future directions for the topic. A substantial amount of research has been devoted to estimating the number of failures that a software system will experience during test and operations, as well as the number of

  16. Actigraphy in human African trypanosomiasis as a tool for objective clinical evaluation and monitoring: a pilot study.

    Directory of Open Access Journals (Sweden)

    Alfred K Njamnshi

    Full Text Available Human African trypanosomiasis (HAT or sleeping sickness leads to a complex neuropsychiatric syndrome with characteristic sleep alterations. Current division into a first, hemolymphatic stage and second, meningoencephalitic stage is primarily based on the detection of white blood cells and/or trypanosomes in the cerebrospinal fluid. The validity of this criterion is, however, debated, and novel laboratory biomarkers are under study. Objective clinical HAT evaluation and monitoring is therefore needed. Polysomnography has effectively documented sleep-wake disturbances during HAT, but could be difficult to apply as routine technology in field work. The non-invasive, cost-effective technique of actigraphy has been widely validated as a tool for the ambulatory evaluation of sleep disturbances. In this pilot study, actigraphy was applied to the clinical assessment of HAT patients.Actigraphy was recorded in patients infected by Trypanosoma brucei gambiense, and age- and sex-matched control subjects. Simultaneous nocturnal polysomnography was also performed in the patients. Nine patients, including one child, were analyzed at admission and two of them also during specific treatment. Parameters, analyzed with user-friendly software, included sleep time evaluated from rest-activity signals, rest-activity rhythm waveform and characteristics. The findings showed sleep-wake alterations of various degrees of severity, which in some patients did not parallel white blood cell counts in the cerebrospinal fluid. Actigraphic recording also showed improvement of the analyzed parameters after treatment initiation. Nocturnal polysomnography showed alterations of sleep time closely corresponding to those derived from actigraphy.The data indicate that actigraphy can be an interesting tool for HAT evaluation, providing valuable clinical information through simple technology, well suited also for long-term follow-up. Actigraphy could therefore objectively contribute to

  17. Molecular Tools for Monitoring the Ecological Sustainability of a Stone Bio-Consolidation Treatment at the Royal Chapel, Granada

    Science.gov (United States)

    Jroundi, Fadwa; Gonzalez-Muñoz, Maria Teresa; Sterflinger, Katja; Piñar, Guadalupe

    2015-01-01

    . The molecular strategy employed here is suggested as an efficient monitoring tool to assess the impact on the stone-autochthonous microbiota of the application of biomineralization processes as a restoration/conservation procedure. PMID:26222040

  18. Molecular Tools for Monitoring the Ecological Sustainability of a Stone Bio-Consolidation Treatment at the Royal Chapel, Granada.

    Directory of Open Access Journals (Sweden)

    Fadwa Jroundi

    as an efficient monitoring tool to assess the impact on the stone-autochthonous microbiota of the application of biomineralization processes as a restoration/conservation procedure.

  19. Development and implementation of tools for self-monitoring of staff exposed to 131I in nuclear medicine centres of Chile

    International Nuclear Information System (INIS)

    Diaz-Londono, G.; Garcia, M.; Astudillo, R.; Hermosilla, A.

    2017-01-01

    Currently in Chile, there are about 42 nuclear medicine centres that mainly use 99m Tc and 131 I in diagnostic and therapeutic procedures. Therefore, staff performs various tasks that increase the risk of internal incorporation and the need to implement routine monitoring programmes. This article shows tools for self-monitoring of staff who exposed to 131 I from measurements in thyroid and urine samples, using the gamma cameras of Nuclear Medicine Units. Then, the calibration factors of gamma cameras of participating units were determined, and a one-worker dose was calculated due to internal incorporation, using an Excel spreadsheet for self-monitoring. The worker who handles 131 I in one of the studied units was monitored for 6 months. The goal of this study is to implement a routine self-monitoring programme for the estimation of committed effective dose of staff exposed to 131 I using gamma cameras in Nuclear Medicine Units of clinical centres in Chile. (authors)

  20. Informing the Design of "Lifestyle Monitoring" Technology for the Detection of Health Deterioration in Long-Term Conditions: A Qualitative Study of People Living With Heart Failure.

    Science.gov (United States)

    Hargreaves, Sarah; Hawley, Mark S; Haywood, Annette; Enderby, Pamela M

    2017-06-28

    Health technologies are being developed to help people living at home manage long-term conditions. One such technology is "lifestyle monitoring" (LM), a telecare technology based on the idea that home activities may be monitored unobtrusively via sensors to give an indication of changes in health-state. However, questions remain about LM technology: how home activities change when participants experience differing health-states; and how sensors might capture clinically important changes to inform timely interventions. The objective of this paper was to report the findings of a study aimed at identifying changes in activity indicative of important changes in health in people with long-term conditions, particularly changes indicative of exacerbation, by exploring the relationship between home activities and health among people with heart failure (HF). We aimed to add to the knowledge base informing the development of home monitoring technologies designed to detect health deterioration in order to facilitate early intervention and avoid hospital admissions. This qualitative study utilized semistructured interviews to explore everyday activities undertaken during the three health-states of HF: normal days, bad days, and exacerbations. Potential recruits were identified by specialist nurses and attendees at an HF support group. The sample was purposively selected to include a range of experience of living with HF. The sample comprised a total of 20 people with HF aged 50 years and above, and 11 spouses or partners of the individuals with HF. All resided in Northern England. Participant accounts revealed that home activities are in part shaped by the degree of intrusion from HF symptoms. During an exacerbation, participants undertook activities specifically to ease symptoms, and detailed activity changes were identified. Everyday activity was also influenced by a range of factors other than health. The study highlights the importance of careful development of LM

  1. Water Quality of Urban Streams: The Allium cepa Seeds/Seedlings Test as a Tool for Surface Water Monitoring

    Directory of Open Access Journals (Sweden)

    Camila Gonçalves Athanásio

    2014-01-01

    Full Text Available The present study investigates the genotoxic, mutagenic, and cytotoxic potential of surface waters in urban streams using Allium cepa and analyzes the applicability of this assay for environmental monitoring. Water samples were collected from three streams located in the urban area of a municipality in the south of Brazil. For each stream, two samples were collected, one upstream and one downstream of the pollution discharge site. Physicochemical evaluation indicated that all samples had various degrees of environmental impact, but substantial impact was seen for the downstream samples of the Preto and Pedras streams. All samples increased the frequency of chromosome aberrations (P<0.05. The sample from Pedras downstream site also caused a decrease in mitotic index (P<0.08 and increase in micronuclei (P<0.08 frequency, indicating potential cytotoxicity and mutagenicity. The Pedras stream receives mixed industrial and urban wastewater, while the Lajeado and Preto streams receive wastewater predominantly domestic in nature, which may partially explain the difference in toxicity among the samples. Moreover, the Allium cepa seeds/seedlings were shown to be extremely sensitive in detecting the genotoxicity of environmental water samples and can be applied as the first tool for environmental health hazard identification and prediction.

  2. Evaluation of the HACCP System in a University Canteen: Microbiological Monitoring and Internal Auditing as Verification Tools

    Science.gov (United States)

    Osimani, Andrea; Aquilanti, Lucia; Tavoletti, Stefano; Clementi, Francesca

    2013-01-01

    Food safety is essential in mass catering. In Europe, Regulation (EC) No. 852/2004 requires food business operators to put in place, implement and maintain permanent procedures based on Hazard Analysis and Critical Control Point (HACCP) principles. Each HACCP plan is specifically implemented for the processing plant and processing methods and requires a systematic collection of data on the incidence, elimination, prevention, and reduction of risks. In this five-year-study, the effectiveness of the HACCP plan of a University canteen was verified through periodic internal auditing and microbiological monitoring of meals, small equipment, cooking tools, working surfaces, as well as hands and white coats of the canteen staff. The data obtained revealed no safety risks for the consumers, since Escherichia coli, Salmonella spp. and Listeria monocytogenes were never detected; however, a quite discontinuous microbiological quality of meals was revealed. The fluctuations in the microbial loads of mesophilic aerobes, coliforms, Staphylococcus aureus, Bacillus cereus, and sulphite-reducing clostridia were mainly ascribed to inadequate handling or processing procedures, thus suggesting the need for an enhancement of staff training activities and for a reorganization of tasks. Due to the wide variety of the fields covered by internal auditing, the full conformance to all the requirements was never achieved, though high scores, determined by assigning one point to each answer which matched with the requirements, were achieved in all the years. PMID:23594937

  3. The glucose ketone index calculator: a simple tool to monitor therapeutic efficacy for metabolic management of brain cancer.

    Science.gov (United States)

    Meidenbauer, Joshua J; Mukherjee, Purna; Seyfried, Thomas N

    2015-01-01

    Metabolic therapy using ketogenic diets (KD) is emerging as an alternative or complementary approach to the current standard of care for brain cancer management. This therapeutic strategy targets the aerobic fermentation of glucose (Warburg effect), which is the common metabolic malady of most cancers including brain tumors. The KD targets tumor energy metabolism by lowering blood glucose and elevating blood ketones (β-hydroxybutyrate). Brain tumor cells, unlike normal brain cells, cannot use ketone bodies effectively for energy when glucose becomes limiting. Although plasma levels of glucose and ketone bodies have been used separately to predict the therapeutic success of metabolic therapy, daily glucose levels can fluctuate widely in brain cancer patients. This can create difficulty in linking changes in blood glucose and ketones to efficacy of metabolic therapy. A program was developed (Glucose Ketone Index Calculator, GKIC) that tracks the ratio of blood glucose to ketones as a single value. We have termed this ratio the Glucose Ketone Index (GKI). The GKIC was used to compute the GKI for data published on blood glucose and ketone levels in humans and mice with brain tumors. The results showed a clear relationship between the GKI and therapeutic efficacy using ketogenic diets and calorie restriction. The GKIC is a simple tool that can help monitor the efficacy of metabolic therapy in preclinical animal models and in clinical trials for malignant brain cancer and possibly other cancers that express aerobic fermentation.

  4. Evaluation of the HACCP System in a University Canteen: Microbiological Monitoring and Internal Auditing as Verification Tools

    Directory of Open Access Journals (Sweden)

    Stefano Tavoletti

    2013-04-01

    Full Text Available Food safety is essential in mass catering. In Europe, Regulation (EC No. 852/2004 requires food business operators to put in place, implement and maintain permanent procedures based on Hazard Analysis and Critical Control Point (HACCP principles. Each HACCP plan is specifically implemented for the processing plant and processing methods and requires a systematic collection of data on the incidence, elimination, prevention, and reduction of risks. In this five-year-study, the effectiveness of the HACCP plan of a University canteen was verified through periodic internal auditing and microbiological monitoring of meals, small equipment, cooking tools, working surfaces, as well as hands and white coats of the canteen staff. The data obtained revealed no safety risks for the consumers, since Escherichia coli, Salmonella spp. and Listeria monocytogenes were never detected; however, a quite discontinuous microbiological quality of meals was revealed. The fluctuations in the microbial loads of mesophilic aerobes, coliforms, Staphylococcus aureus, Bacillus cereus, and sulphite-reducing clostridia were mainly ascribed to inadequate handling or processing procedures, thus suggesting the need for an enhancement of staff training activities and for a reorganization of tasks. Due to the wide variety of the fields covered by internal auditing, the full conformance to all the requirements was never achieved, though high scores, determined by assigning one point to each answer which matched with the requirements, were achieved in all the years.

  5. Evaluation of the HACCP system in a university canteen: microbiological monitoring and internal auditing as verification tools.

    Science.gov (United States)

    Osimani, Andrea; Aquilanti, Lucia; Tavoletti, Stefano; Clementi, Francesca

    2013-04-17

    Food safety is essential in mass catering. In Europe, Regulation (EC) No. 852/2004 requires food business operators to put in place, implement and maintain permanent procedures based on Hazard Analysis and Critical Control Point (HACCP) principles. Each HACCP plan is specifically implemented for the processing plant and processing methods and requires a systematic collection of data on the incidence, elimination, prevention, and reduction of risks. In this five-year-study, the effectiveness of the HACCP plan of a University canteen was verified through periodic internal auditing and microbiological monitoring of meals, small equipment, cooking tools, working surfaces, as well as hands and white coats of the canteen staff. The data obtained revealed no safety risks for the consumers, since Escherichia coli, Salmonella spp. and Listeria monocytogenes were never detected; however, a quite discontinuous microbiological quality of meals was revealed. The fluctuations in the microbial loads of mesophilic aerobes, coliforms, Staphylococcus aureus, Bacillus cereus, and sulphite-reducing clostridia were mainly ascribed to inadequate handling or processing procedures, thus suggesting the need for an enhancement of staff training activities and for a reorganization of tasks. Due to the wide variety of the fields covered by internal auditing, the full conformance to all the requirements was never achieved, though high scores, determined by assigning one point to each answer which matched with the requirements, were achieved in all the years.

  6. Computer vision-based analysis of foods: a non-destructive colour measurement tool to monitor quality and safety.

    Science.gov (United States)

    Mogol, Burçe Ataç; Gökmen, Vural

    2014-05-01

    Computer vision-based image analysis has been widely used in food industry to monitor food quality. It allows low-cost and non-contact measurements of colour to be performed. In this paper, two computer vision-based image analysis approaches are discussed to extract mean colour or featured colour information from the digital images of foods. These types of information may be of particular importance as colour indicates certain chemical changes or physical properties in foods. As exemplified here, the mean CIE a* value or browning ratio determined by means of computer vision-based image analysis algorithms can be correlated with acrylamide content of potato chips or cookies. Or, porosity index as an important physical property of breadcrumb can be calculated easily. In this respect, computer vision-based image analysis provides a useful tool for automatic inspection of food products in a manufacturing line, and it can be actively involved in the decision-making process where rapid quality/safety evaluation is needed. © 2013 Society of Chemical Industry.

  7. Application of geographic information system as a tool for environmental monitoring in support of a nuclear installation

    International Nuclear Information System (INIS)

    Ribeiro, Glaucielen F.; Silva, Nivaldo C.; Oliveira, Alexandre P.; Ferrari, Talita N.; Dias, Danila C.; Alberti, Heber Luiz C.

    2013-01-01

    The increasing advance of technologies of geographic information systems (GIS), computer processing techniques, and the growing volume of spatial data available and demand for automated systems to aid decision making are motivating enterprises and research institutions to make use of GIS technologies and Intelligent Computing. In this context, the Laboratory of Pocos de Caldas (LAPOC) has a large collection of data that are generated from environmental monitoring of a nuclear installation. These data can be organized through a georeferenced database in order to improve the quality of information, in addition to generating new interpretations from data and existing products. Therefore, this study aims to generate a database that is capable of gathering existing data into a Geographic Information System (GIS) platform using ArcGIS 9.3.1 software which has a model of relational database that stores geographic data in Geodatabase format. The steps of this process start with the organization of spatial and descriptive data, moving through logic and conceptual modeling and finally, implementation of the database into the GIS environment. The data modeling through the Geodatabase was adequate since its structure enabled the data work to be done in an efficient manner in addition to allowing centralized management of such data. This demonstrates the great potential of the tool and improvement of the quality and availability of information. (author)

  8. Inverter ratio failure detector

    Science.gov (United States)

    Wagner, A. P.; Ebersole, T. J.; Andrews, R. E. (Inventor)

    1974-01-01

    A failure detector which detects the failure of a dc to ac inverter is disclosed. The inverter under failureless conditions is characterized by a known linear relationship of its input and output voltages and by a known linear relationship of its input and output currents. The detector includes circuitry which is responsive to the detector's input and output voltages and which provides a failure-indicating signal only when the monitored output voltage is less by a selected factor, than the expected output voltage for the monitored input voltage, based on the known voltages' relationship. Similarly, the detector includes circuitry which is responsive to the input and output currents and provides a failure-indicating signal only when the input current exceeds by a selected factor the expected input current for the monitored output current based on the known currents' relationship.

  9. Biological effects-based tools for monitoring impacted surface waters in the Great Lakes: a multiagency program in support of the Great Lakes Restoration Initiative

    Science.gov (United States)

    Ekman, Drew R.; Ankley, Gerald T.; Blazer, Vicki; Collette, Timothy W.; Garcia-Reyero, Natàlia; Iwanowicz, Luke R.; Jorgensen, Zachary G.; Lee, Kathy E.; Mazik, Pat M.; Miller, David H.; Perkins, Edward J.; Smith, Edwin T.; Tietge, Joseph E.; Villeneuve, Daniel L.

    2013-01-01

    There is increasing demand for the implementation of effects-based monitoring and surveillance (EBMS) approaches in the Great Lakes Basin to complement traditional chemical monitoring. Herein, we describe an ongoing multiagency effort to develop and implement EBMS tools, particularly with regard to monitoring potentially toxic chemicals and assessing Areas of Concern (AOCs), as envisioned by the Great Lakes Restoration Initiative (GLRI). Our strategy includes use of both targeted and open-ended/discovery techniques, as appropriate to the amount of information available, to guide a priori end point and/or assay selection. Specifically, a combination of in vivo and in vitro tools is employed by using both wild and caged fish (in vivo), and a variety of receptor- and cell-based assays (in vitro). We employ a work flow that progressively emphasizes in vitro tools for long-term or high-intensity monitoring because of their greater practicality (e.g., lower cost, labor) and relying on in vivo assays for initial surveillance and verification. Our strategy takes advantage of the strengths of a diversity of tools, balancing the depth, breadth, and specificity of information they provide against their costs, transferability, and practicality. Finally, a series of illustrative scenarios is examined that align EBMS options with management goals to illustrate the adaptability and scaling of EBMS approaches and how they can be used in management decisions.

  10. Numerical Implementation of Indicators and Statistical Control Tools in Monitoring and Evaluating CACEI-ISO Indicators of Study Program in Industrial Process by Systematization

    Science.gov (United States)

    Ayala, Gabriela Cota; Real, Francia Angélica Karlos; Ivan, Ramirez Alvarado Edqar

    2016-01-01

    The research was conducted to determine if the study program of the career of industrial processes Technological University of Chihuahua, 1 year after that it was certified by CACEI, continues achieving the established indicators and ISO 9001: 2008, implementing quality tools, monitoring of essential indicators are determined, flow charts are…

  11. The advent of failure analysis software technology

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, C.L. [Sandia National Labs., Albuquerque, NM (United States); Barnard, R.D. [Schlumberger Technologies, San Jose, CA (United States)

    1994-02-01

    The increasing complexity of integrated circuits demands that software tools, in addition to hardware tools, be used for successful diagnosis of failure. A series of customizable software tools have been developed that organize failure analysis information and provide expert level help to failure analysts to increase their productivity and success.

  12. GeneXpert HIV-1 quant assay, a new tool for scale up of viral load monitoring in the success of ART programme in India.

    Science.gov (United States)

    Kulkarni, Smita; Jadhav, Sushama; Khopkar, Priyanka; Sane, Suvarna; Londhe, Rajkumar; Chimanpure, Vaishali; Dhilpe, Veronica; Ghate, Manisha; Yelagate, Rajendra; Panchal, Narayan; Rahane, Girish; Kadam, Dilip; Gaikwad, Nitin; Rewari, Bharat; Gangakhedkar, Raman

    2017-07-21

    Recent WHO guidelines identify virologic monitoring for diagnosing and confirming ART failure. In view of this, validation and scale up of point of care viral load technologies is essential in resource limited settings. A systematic validation of the GeneXpert® HIV-1 Quant assay (a point-of-care technology) in view of scaling up HIV-1 viral load in India to monitor the success of national ART programme was carried out. Two hundred nineteen plasma specimens falling in nine viral load ranges (5 L copies/ml) were tested by the Abbott m2000rt Real Time and GeneXpert HIV-1 Quant assays. Additionally, 20 seronegative; 16 stored specimens and 10 spiked controls were also tested. Statistical analysis was done using Stata/IC and sensitivity, specificity, PPV, NPV and %misclassification rates were calculated as per DHSs/AISs, WHO, NACO cut-offs for virological failure. The GeneXpert assay compared well with the Abbott assay with a higher sensitivity (97%), specificity (97-100%) and concordance (91.32%). The correlation between two assays (r = 0.886) was statistically significant (p performance and rapidity will aid in timely diagnosis of ART failures, integrated HIV-TB management and will facilitate the UNAIDS 90-90-90 target.

  13. Resolution of sonographic B-lines as a measure of pulmonary decongestion in acute heart failure.

    Science.gov (United States)

    Martindale, Jennifer L

    2016-06-01

    Objective noninvasive measures of dyspnea in patients with acute heart failure are lacking. In this review, we describe lung ultrasound as a tool to estimate the degree of pulmonary congestion in patients presenting with acute heart failure and to monitor therapeutic efficacy. Serial semiquantitative measures of sonographic B-lines in acute heart failure patients can be converted to pulmonary edema scores obtained at admission and hospital discharge. These scores provide prognostic information for short-term clinical outcomes. Lung ultrasound has the potential to measure changes in pulmonary edema during acute heart failure management and improve risk stratification. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Persistent atrial fibrillation worsens heart rate variability, activity and heart rate, as shown by a continuous monitoring by implantable biventricular pacemakers in heart failure patients.

    Science.gov (United States)

    Puglisi, Andrea; Gasparini, Maurizio; Lunati, Maurizio; Sassara, Massimo; Padeletti, Luigi; Landolina, Maurizio; Botto, Giovanni Luca; Vincenti, Antonio; Bianchi, Stefano; Denaro, Alessandra; Grammatico, Andrea; Boriani, Giuseppe

    2008-07-01

    Atrial fibrillation (AF) induces loss of atrial contribution, heart rate irregularity, and fast ventricular rate. The objectives of the study were to accurately measure AF incidence and to investigate the mutual temporal patterns of AF and heart failure (HF) in patients indicated to cardiac resynchronization therapy. Four hundred ten consecutive patients (70% male, age 69 +/- 11) with advanced HF (NYHA = 3.0 +/- 0.6), low ejection fraction (EF = 27 +/- 9%), and ventricular conduction delay (QRS = 165 +/- 29 ms) received a biventricular pacemaker. Enrolled patients were divided into two groups: G1 = 249 patients with no AF history, G2 = 161 patients with history of paroxysmal/persistent AF. In a median follow-up of 13 months, AF episodes longer than 5 minutes occurred in 105 of 249 (42.2%) G1 patients and 76 of 161 (47.2%) G2 patients, while AF episodes longer than one day occurred in 14 of 249 (5.6%) G1 patients and in 36 of 161 (22.4%) G2 patients. Device diagnostics monitored daily values of patient activity, night heart rate (NHR), and heart rate variability (HRV). Comparing 30-day periods before AF onset and during persistent AF, significant (P R(2)= 0.73) with activity, with a significant lower activity associated with NHR >or= 88 bpm. AF is frequent in HF patients. Persistent AF is associated with statistically significant decrease in patient activity and HRV and NHR increase.

  15. Failure of frank-starling mechanism detected on radionuclide ambulatory monitoring (C-vest II) is associated with severe prognosis in ischemic dilatative cardiomyopathy

    International Nuclear Information System (INIS)

    Carboni, G.P.

    2004-01-01

    Background: Global perfusion scoring when combined to measures of left ventricular (LV) ejection fraction (EF), LV volumes and LV diastolic function during daily life activities could explain the mechanisms for severe prognosis IN ISCHEMIC DILATATIVE CARDIOMYOPATHY (ICMP). Methods: After a routine Tl-gated SPECT, 13 consecutive pts with ICMP in whom the indication for revascularization procedures had been excluded, mean age of 68 +-8 years, with < 30% LV EF and an abnormal exercise defect (ex AD) of an extent of 27+-17% pixels with reversibility (R) of 13+-25% pixels on polar maps were carefully selected. After 1 week time, global LV function was then continuously monitored by radionuclide ambulatory monitoring (VEST) and rest basal values were immediately validated against multigated blood pool analysis (MUGA). VEST recordings lasted for an average time of 242+-126 min. Results: When EFs measured on MUGA and VEST were compared there was any significant difference (30+-9% vs 27+-11%, p=ns),while Bland-Altman plotting revealed a mean difference /average of 0.09% and a SD difference of 0.2%. When on VEST, values at rest such as heart rate (HR), EFs, end-diastolic volumes (EDVs), end-systolic volumes (ESVs) and PFR were compared with the same values measured during stair climbing (SC) there was any difference in EDVs (104 +-5 mlvs 103+- 19 ml,p = ns) but not for HR (86+-12 bpmvs 102+-15 bpm,p < 0.05), ESVs (73+-11% vs 62+-17%, p < 0.04), EFs ( 30+-9% vs 38+-13%, p < 0.05) and PFR values (1.3+-0.3 edv/s vs 2.0+-0.6 edv/s, p < 0.02), respectively .A ratio of 38% (5/13) severe cardiovascular events (1 death , 1 stroke and 3 re-hospitalizations for heart failure ) was observed in a 4+-1 months follow-up.In a multiple regression model were then considered on VEST 10 variables (F-value = 217, significance of the model, p< 0.05): age, EFs, EDVs, ESVs and PFR values at rest, EDVs, ESVs and PFR values during SC, extent of ex AD and extent of R of ex AD.on T1-SPECT. Of these

  16. Application of Circulating Tumor DNA as a Non-Invasive Tool for Monitoring the Progression of Colorectal Cancer.

    Directory of Open Access Journals (Sweden)

    Jiaolin Zhou

    Full Text Available Liquid biopsy has been proposed to be a promising noninvasive tool to obtain information on tumor progression. Through a clinical observation of a case series of 6 consecutive patients, we aim to determine the value of circulating tumor DNA (ctDNA for monitoring the tumor burden during the treatment of colorectal cancer (CRC.We used capture sequencing of 545 genes to identify somatic alternations in primary tumor tissues of the six CRC patients who underwent radical surgery and in 23 plasma samples collected at serial time points. We compared the mutation patterns and variant allele frequencies (VAFs between the matched tissue and the plasma samples and evaluated the potential advantage of using ctDNA as a better tumor load indicator to detect disease relapse over carcinoembryonic antigen (CEA, cancer antigen (CA 19-9 and imaging studies.We identified low-frequency mutations with a mean VAF of 0.88% (corresponding to a mean tumor burden of 0.20ng/mL in the preoperative plasmas of four patients with locally advanced CRC and a subset of mutations shared by their primary tumors. The tumor loads appeared a sudden decrease upon surgery or other adjuvant treatments and then generally maintained at low levels (0.092ng/mL until disease recurred. ctDNA increased by 13-fold when disease relapsed in one patient while the CEA and CA 19-9 levels remained normal. In this patient, all six somatic mutations identified in the preoperative plasma were detected in the recrudescent plasma again, with five mutations showing allele fraction increase.We described a multi-time-point profile of ctDNA of CRC patients during the course of comprehensive treatment and observed a correlation of ctDNA level with the clinically evaluated tumor progression. This demonstrated a new strategy by analyzing the heterogeneous ctDNA to evaluate and monitor the tumor burden in the treatment and follow-up of CRC patients, with potentially better potency than conventional biomarkers.

  17. The potential use of spectral electromyographic fatigue as a screening and outcome monitoring tool of sarcopenic back muscle alterations.

    Science.gov (United States)

    Kienbacher, Thomas; Habenicht, Richard; Starek, Christian; Mair, Patrick; Wolf, Markus; Paul, Birgit; Riegler, Sara; Kollmitzer, Josef; Ebenbichler, Gerold

    2014-07-02

    the clinical relevance of the IMF-EMG relative to the MF-EMG slope declines, spectral EMG may also be used as an outcome monitoring tool in elderly populations.

  18. [The Jena Anxiety Monitoring List (JAMoL) - a tool for the evidence-based treatment of panic disorder with or without agoraphobia in primary care].

    Science.gov (United States)

    Hiller, Thomas Stephan; Freytag, Antje; Breitbart, Jörg; Teismann, Tobias; Schöne, Elisabeth; Blank, Wolfgang; Schelle, Mercedes; Vollmar, Horst Christian; Margraf, Jürgen; Gensichen, Jochen

    2018-04-01

    Behavior therapy-oriented methods are recommended for treating anxiety disorders in primary care. The treatment of patients with long-term conditions can be improved by case management and structured clinical monitoring. The present paper describes the rationale, design and application of the 'Jena Anxiety Monitoring List' (JAMoL), a monitoring tool for the treatment of patients with panic disorder, with or without agoraphobia, in primary care. JAMoL's design was based on established clinical measures, the rationale of exposure-based anxiety treatment, and research on family practice-based case management. After piloting, the JAMoL was used in the clinical study 'Jena-PARADISE' (ISRCTN64669297), where non-physician practice staff monitored patients with panic disorder by telephone. Using semi-structured interviews in concomitant studies, study participants were asked about the instrument's functionality. The JAMoL assesses the severity of anxiety symptoms (6 items) as well as the patient's adherence to therapy (4 items) and fosters the case management-related information exchange (3 items). An integrated traffic light scheme facilitates the evaluation of monitoring results. Within the clinical study, non-physician practice staff carried out a total of 1,525 JAMoL-supported monitoring calls on 177 patients from 30 primary care practices (median calls per patient: 10 [interquartile range, 9-10]). Qualitative analyses revealed that most practice teams and patients rated the JAMoL as a practicable and treatment-relevant tool. The JAMoL enables primary care practice teams to continuously monitor anxiety symptoms and treatment adherence in patients with panic disorder with or without agoraphobia. Within the behavior therapy-oriented treatment program 'Jena-PARADISE', the JAMoL constitutes an important case management tool. Copyright © 2018. Published by Elsevier GmbH.

  19. Using SaudiVeg Ecoinformatics in assessment, monitoring and proposing environmental restoration tools in central Saudi Arabia

    Science.gov (United States)

    El-Sheikh, Mohamed; Hennekens, Stephan; Alfarhan, Ahmed; Thomas, Jacob; Schaminee, Joop; El-Keblawy, Ali

    2017-04-01

    Successful restoration of degraded habitats requires information about the history and factors led to the deterioration of these habitats. This study analyzed SaudiVeg Ecoinformatics, which is a big phytosociological database about plant communities and other environmental factors affecting them in the Najd-Central Region of Saudi Arabia. A phytosociological survey with more than 3000 vegetation relevés was conducted during 2013. The data were used to correlate the plant community attributes, such as abundance and species diversity in natural and ruderal habitats with environmental factors, such as human impacts, soil physical and chemical properties, and land uses. The data were subjected to multivariate analyses using programs, such as TWINSPAN, DCA and CCA, via Juice package. Fourteen vegetation associations were described under provisional classification of the Central Saudi Arabia deserts. These associations were broadly grouped into desert vegetation types. One alliance group, Haloxylonion salicornici, is the most widespread and contains four associations on the wadis and desert plains. Three associations are dominant on the depression habitats (raudhas) and two associations of Tamarixidetum spp. on the wetland and salt pan habitats. Four associations inhabit the man-made habitat and abandoned field habitats and one association, the Neurado procumbentis-Heliotropietum digyni, dominates the overgrazed sandy dunes. As human impact is huge and increasing, the vegetation ecoinformatics of the present study would form a baseline description that could be used as a vital tool for future monitoring and for proposing environmental restoration processes in central Saudi Arabia. It could also help both Governmental and Non-governmental organizations (NGO) in formulating strategies and on-ground plans for protection, management and restoration of the natural vegetation.

  20. A comparison of an opioid abuse screening tool and prescription drug monitoring data in the emergency department.

    Science.gov (United States)

    Weiner, Scott G; Horton, Laura C; Green, Traci C; Butler, Stephen F

    2016-02-01

    This study aimed to: (a) determine the percentage of ED patients receiving prescriptions for opioid pain medications that meet the criteria for "high-risk for abuse potential" on the Screener and Opioid Assessment for Patients with Pain (SOAPP(®)-R), (b) determine the percentage of patients with high-risk behavior on the state prescription drug monitoring program (PDMP) database, (c) compare the SOAPP-R with data from the PDMP, and (d) determine psychometric properties of SOAPP-R for ED patients Convenience sample of ED patients who were being considered for discharge with a prescription for an opioid pain medication. Subjects completed SOAPP-R on an electronic tablet and PDMP data was obtained. Scores on SOAPP-R ≥ 18 were defined as "at-risk", and PDMP data showing both ≥ 4 opioid prescriptions and ≥ 4 providers in 12 months was considered the criterion standard for high-risk behavior. 82 patients (88.2%) provided consent. 32.9% (n=27) were determined to be "at-risk" (score ≥ 18) by SOAPP-R. 15.9% (n=13) subjects met PDMP criteria and 53.9% (n=7) of those had SOAPP-R scores ≥ 18 (sensitivity 54%, specificity 71%, positive predictive value 26%, negative predictive value 89%). The association of an at-risk SOAPP-R score and PDMP high-risk criteria was an adjusted odds ratio of 1.39 (95% confidence interval 0.73-3.68). In our population, about one-third of patients being considered for discharge with an opioid prescription scored "at-risk" on SOAPP-R and 15.9% met the PDMP high-risk criteria. The high negative predictive value of SOAPP-R indicates it may be a useful screening tool for the ED patient population. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  1. Tools for diagnosis, monitoring and screening of Schistosoma infections utilizing lateral-flow based assays and upconverting phosphor labels

    Science.gov (United States)

    CORSTJENS, PAUL L. A. M.; DE DOOD, CLAUDIA J.; KORNELIS, DIEUWKE; FAT, ELISA M. TJON KON; WILSON, R. ALAN; KARIUKI, THOMAS M.; NYAKUNDI, RUTH K.; LOVERDE, PHILIP T.; ABRAMS, WILLIAM R.; TANKE, HANS J.; VAN LIESHOUT, LISETTE; DEELDER, ANDRÉ M.; VAN DAM, GOVERT J.

    2014-01-01

    SUMMARY The potential of various quantitative lateral flow (LF) based assays utilizing up-converting phosphor (UCP) reporters for the diagnosis of schistosomiasis is reviewed including recent developments. Active infections are demonstrated by screening for the presence of regurgitated worm antigens (genus specific polysaccharides), whereas anti-Schistosoma antibodies may indicate ongoing as well as past infections. The circulating anodic antigen (CAA) in serum or urine (and potentially also saliva) is identified as the marker that may allow detection of single-worm infections. Quantitation of antigen levels is a reliable method to study effects of drug administration, worm burden and anti-fecundity mechanisms. Moreover, the ratio of CAA and circulating cathodic antigen (CCA) is postulated to facilitate identification of either Schistosoma mansoni or Schistosoma haematobium infections. The UCP-LF assays allow simultaneous detection of multiple targets on a single strip, a valuable feature for antibody detection assays. Although antibody detection in endemic regions is not a useful tool to diagnose active infections, it gains potential when the ratio of different classes of antibody specific for the parasite/disease can be determined. The UCP-LF antibody assay format allows this type of multiplexing, including testing a linear array of up to 20 different targets. Multiple test spots would allow detection of specific antibodies, e.g. against different Schistosoma species or other pathogens as soil-transmitted helminths. Concluding, the different UCP-LF based assays for diagnosis of schistosomiasis provide a collection of tests with relatively low complexity and high sensitivity, covering the full range of diagnostics needed in control programmes for mapping, screening and monitoring. PMID:24932595

  2. Evaluation of in-line spatial filter velocimetry as PAT monitoring tool for particle growth during fluid bed granulation.

    Science.gov (United States)

    Burggraeve, A; Van Den Kerkhof, T; Hellings, M; Remon, J P; Vervaet, C; De Beer, T

    2010-09-01

    In this study, the feasibility of spatial filter velocimetry (SFV) as process analytical technology tool for the in-line monitoring of the particle size distribution during top spray fluidized bed granulation was examined. The influence of several process (inlet air temperature during spraying and drying) and formulation variables (HPMC and Tween 20 concentration) upon the particle size distribution during processing, and the end product particle size distribution, tapped density and Hausner ratio was examined using a design of experiments (DOE) (2-level full factorial design, 19 experiments). The trend in end granule particle size distributions of all DOE batches measured with in-line SFV was similar to the off-line laser diffraction (LD) data. Analysis of the DOE results showed that mainly the HPMC concentration and slightly the inlet air temperature during drying had a positive effect on the average end granule size. The in-line SFV particle size data, obtained every 10s during processing, further allowed to explain and better understand the (in)significance of the studied DOE variables, which was not possible based on the LD data as this technique only supplied end granule size information. The variation in tapped density and Hausner ratio among the end granules of the different DOE batches could be explained by their difference in average end granule size. Univariate, multivariate PLS and multiway N-PLS models were built to relate these end granule properties to the in-line-measured particle size distribution. The multivariate PLS tapped density model and the multiway N-PLS Hausner ratio model showed the highest R(2) values in combination with the lowest RMSEE values (R(2) of 82% with an RMSEE of 0.0279 for tapped density and an R(2) of 52% with an RMSEE of 0.0268 for Hausner ratio, respectively). 2010 Elsevier B.V. All rights reserved.

  3. Real-time potentiometric sensor; an innovative tool for monitoring hydrolysis of chemo/bio-degradable drugs in pharmaceutical sciences.

    Science.gov (United States)

    Ma'mun, Ahmed; Abd El-Rahman, Mohamed K; Abd El-Kawy, Mohamed

    2018-05-30

    In recent years, the whole field of ion-selective electrodes(ISEs) in pharmaceutical sciences has expanded far beyond its original roots. The diverse range of opportunities offered by ISEs was broadly used in a number of pharmaceutical applications, with topics presented ranging from bioanalysis of drugs and metabolites, to protein binding studies, green analytical chemistry, impurity profiling, and drug dissolution in biorelevant media. Inspired from these advances and with the aim of extending the functional capabilities of ISEs, the primary focus of the present paper is the utilization of ISE as a tool in personalized medicine. Given the opportunity to explore biological events in real-time (such as drug metabolism) could be central to personalized medicine. (ATR) is a chemo-degradable and bio-degradable pharmaceutically active drug. Laudanosine (LDS) is the major degradation product and metabolite of ATR and is potentially toxic and reported to possess epileptogenic activity which increases the risk of convulsive effects. In this work, ATR have been subjected to both chemical and biological hydrolysis, and the course of the reactions is monitored by means of a ISE. In this study, we have designed an efficient real-time tracking strategy which substantially resolve the challenges of the ATR chemical and biological degradation kinetics. By utilizing a potentiometric sensor, tracking of ATR chemical and biological degradation kinetics can be performed in a very short time with excellent accuracy. The LOD was calculated to be 0.23 μmol L -1 , the potential drift was investigated over a period of 60 min and the value was 0.25 mV h -1 . Real serum samples for measurement the rate of in vitro metabolism of ATR was performed. Furthermore, a full description of the fabricated screen-printed sensor was presented. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Development of a physical activity monitoring tool for Thai medical schools: a protocol for a mixed methods study.

    Science.gov (United States)

    Wattanapisit, Apichai; Vijitpongjinda, Surasak; Saengow, Udomsak; Amaek, Waluka; Thanamee, Sanhapan; Petchuay, Prachyapan

    2017-09-27

    Physical activity (PA) is important in promoting health, as well as in the treatment and prevention of diseases. However, insufficient PA is still a global health problem and it is also a problem in medical schools. PA training in medical curricula is still sparse or non-existent. There is a need for a comprehensive understanding of the extent of PA in medical schools through several indicators, including people, places and policies. This study includes a survey of the PA prevalence in a medical school and development of a tool, the Medical School Physical Activity Report Card (MSPARC), which will contain concise and understandable infographics and information for exploring, monitoring and reporting information relating to PA prevalence. This mixed methods study will run from January to September 2017. We will involve the School of Medicine, Walailak University, Thailand, and its medical students (n=285). Data collection will consist of both primary and secondary data, divided into four parts: general information, people, places and policies. We will investigate the PA metrics about (1) people: the prevalence of PA and sedentary behaviours; (2) place: the quality and accessibility of walkable neighbourhoods, bicycle facilities and recreational areas; and (3) policy: PA promotion programmes for medical students, education metrics and investments related to PA. The MSPARC will be developed using simple symbols, infographics and short texts to evaluate the PA metrics of the medical school. This study has been approved by the Human Research Ethics Committee of Walailak University (protocol number: WUEC-16-005-01). Findings will be published in peer-reviewed journals and presented at national or international conferences. The MSPARC and full report will be disseminated to relevant stakeholders, policymakers, staff and clients. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is

  5. Near infrared spectroscopy as a potential tool to monitor the mineralization of exogenous organic matter within the soil

    Science.gov (United States)

    Fouad, Youssef; Walter, Christian; Morvan, Thierry; Zaouchi, Yousr; Sanaa, Mustapha

    2010-05-01

    state of degradation of organic matter affects soil reflectance in the Vis-NIR. PCA performed with the analytical data discriminates the time according to the 1st axis that explains 50.1% of the observed variance. PCA performed with the reflectance spectra did not show any significant correlation with the time parameter in the 1st factorial plane. However, the 2nd axis of this factorial plane differentiates between soil types. The models calibrated by the mean of PLS to predict direct analytical data (C-CO2, N-NH4 and N-NH3) were quite precise for the cumulative carbon and the mineral nitrogen produced after mineralization of the exogenous organic matter. The performance of these models were R²=0.68-0.78, RMSE=64.92mg C/kg-109.91mg N/kg and ME=3.47mg C/kg-13.94mg N/kg, respectively. Moreover, we have calibrated models to predict the organic carbon (R² = 0.89, RMSE = 352.57 mg C / kg and ME = -50.16mg C / kg) and organic nitrogen (R² = 0.79, RMSE = 9.46% and ME = 0.69%) remaining in the soil samples. The predictions of these indirect variables related to mineralization process were satisfactory. These first results are promising towards the development of a non-intrusive, cheaper and flexible tool to monitor the mineralization of exogenous organic matter within the soil.

  6. Virtual-Instrument-Based Online Monitoring System for Hands-on Laboratory Experiment of Partial Discharges

    Science.gov (United States)

    Karmakar, Subrata

    2017-01-01

    Online monitoring of high-voltage (HV) equipment is a vital tool for early detection of insulation failure. Most insulation failures are caused by partial discharges (PDs) inside the HV equipment. Because of the very high cost of establishing HV equipment facility and the limitations of electromagnetic interference-screened laboratories, only a…

  7. The Healthy Aging Brain Care (HABC) Monitor: validation of the Patient Self-Report Version of the clinical tool designed to measure and monitor cognitive, functional, and psychological health.

    Science.gov (United States)

    Monahan, Patrick O; Alder, Catherine A; Khan, Babar A; Stump, Timothy; Boustani, Malaz A

    2014-01-01

    Primary care providers need an inexpensive, simple, user-friendly, easily standardized, sensitive to change, and widely available multidomain instrument to measure the cognitive, functional, and psychological symptoms of patients suffering from multiple chronic conditions. We previously validated the Caregiver Report Version of the Healthy Aging Brain Care Monitor (HABC Monitor) for measuring and monitoring the severity of symptoms through caregiver reports. The purpose of this study was to assess the reliability and validity of the Patient Self-Report Version of the HABC Monitor (Self-Report HABC Monitor). Cross-sectional study. Primary care clinics affiliated with a safety net urban health care system in Indianapolis, Indiana, USA. A total of 291 subjects aged ≥65 years with a mean age of 72.7 (standard deviation 6.2) years, 76% female, and 56% African Americans. Psychometric validity and reliability of the Self-Report HABC Monitor. Among 291 patients analyzed, the Self-Report HABC Monitor demonstrated excellent fit for the confirmatory factor analysis model (root mean square error of approximation =0.030, comparative fit index =0.974, weighted root mean square residual =0.837) and good internal consistency (0.78-0.92). Adequate convergent-divergent validity (differences between the Telephone Interview for Cognitive Status test-based cognitive function impairment versus nonimpairment groups) was demonstrated only when patients were removed from analysis if they had both cognitive function test impairment and suspiciously perfect self-report HABC Monitor cognitive floor scores of 0. The Self-Report HABC Monitor demonstrates good reliability and validity as a clinically practical multidimensional tool for measuring symptoms. The tool can be used along with its caregiver version to provide useful feedback (via monitoring of symptoms) for modifying care plans. Determining the validity of HABC Monitor scores from patients who self-report a perfect cognitive score of

  8. Intraparenchymal intracranial pressure monitoring in patients with acute liver failure Monitoreo intraparenquimatoso de presión intracraneana en pacientes con falla hepática aguda

    Directory of Open Access Journals (Sweden)

    Alejandra T. Rabadán

    2008-06-01

    Full Text Available BACKGROUND: Elevated intracranial pressure (ICP is a common cause of death in acute liver failure (ALF and is determinant for decision-making regarding the timing of liver transplantation. The recommended type ICP monitoring device is controversial in ALF patients. Epidural devices had less risk of hemorrhagic complications, but they are less reliable than intraparenchymal ones. METHOD: Twenty-three patients with ALF were treated, and 19 of them received a liver transplant. Seventeen patients had ICP monitoring because of grade III-IV encephalopathy. All patients received fresh plasma (2-3 units before and during placing the intraparenchymal device. RESULTS: Eleven cases (64.7% had elevated ICP, and 6 patients (35.2% had normal values. One patient (5.9% had an asymptomatic small intraparenchymal haemorrhage ANTECEDENTES: La presión intracraneana elevada (PIC es una causa frecuente de muerte en la falla hepática aguda (FHA y es determinante para la toma de decisiones respecto del momento del transplante hepático. El tipo de dispositivo para el monitoreo de OIC es controversial em los pacientes em FHA. Los dispositivos epidurales tienen menos riesgo de complicaciones hemorrágicas, pero son menos confiables que los intraparenquimatosos. MÉTODO: Veintitrés pacientes con FHA fueron tratados, y 19 de ellos recibieron un transplante hepático. diecisiete pacientes tuvieron monitoreo de PIC debido a encefalopatía grado III-IV. Todos los pacientes recibieron plasma fresco (2-3 unidades antes y durante la colocación de la fibra intraparenquimatosa. RESULTADOS: Once casos (64.7% tuvieron PIC elevada, y 6 pacientes (35.2% tuvieron valores normales. Un paciente (5.9% tuvo una pequeña hemorragia intraparenquimatosa asintomática <1cm³ en TAC, la cual no impidió el transplante hepático. CONCLUSIÓN: En nuestra experiencia, el monitoreo intraparenquimatoso de presión intracraneana en pacientes con FHA parece ser un método preciso y con bajo riesgo

  9. On the development of system-theoretic tools for the design of integrated health monitoring and controls for rocket propulsion systems

    Science.gov (United States)

    Helmicki, Arthur J.

    1991-01-01

    As NASA continues to develop various advanced propulsion technologies for space exploration, two factors are becoming increasingly dominant in design specifications: increase operational reliability and decrease operational cost. One approach that has been proposed to meet these challenges is to incorporate into current and future rocket propulsion systems some sort of diagnostic/monitoring capability in the form of a Health Monitoring System (HMS). HMS technology offers the promise of increased operational reliability through its ability to assess system performance, detect and isolate degradations and/or failures, and modify system operation so as to minimize negative effects on performance. The purpose of this research is to study, from a systems engineering perspective, the particular issues of analysis and synthesis for generic HMS's.

  10. ATAQS: A computational software tool for high throughput transition optimization and validation for selected reaction monitoring mass spectrometry

    Directory of Open Access Journals (Sweden)

    Ramos Hector

    2011-03-01

    Full Text Available Abstract Background Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. Increasingly, proteomic measurements are also supporting hypothesis-driven studies, in which a predetermined set of proteins is consistently detected and quantified in multiple samples. Selected reaction monitoring (SRM is a targeted mass spectrometric technique that supports the detection and quantification of specific proteins in complex samples at high sensitivity and reproducibility. Here, we describe ATAQS, an integrated software platform that supports all stages of targeted, SRM-based proteomics experiments including target selection, transition optimization and post acquisition data analysis. This software will significantly facilitate the use of targeted proteomic techniques and contribute to the generation of highly sensitive, reproducible and complete datasets that are particularly critical for the discovery and validation of targets in hypothesis-driven studies in systems biology. Result We introduce a new open source software pipeline, ATAQS (Automated and Targeted Analysis with Quantitative SRM, which consists of a number of modules that collectively support the SRM assay development workflow for targeted proteomic experiments (project management and generation of protein, peptide and transitions and the validation of peptide detection by SRM. ATAQS provides a flexible pipeline for end-users by allowing the workflow to start or end at any point of the pipeline, and for computational biologists, by enabling the easy extension of java algorithm classes for their own algorithm plug-in or connection via an external web site. This integrated system supports all steps in a SRM-based experiment and provides a user-friendly GUI that can be run by any operating system that allows the installation of the Mozilla Firefox web browser. Conclusions Targeted

  11. Stream sediments analysis for geochemical mapping of Romagna Apennines (Northern Italy): monitoring and management tool of environmental resources at various scales

    OpenAIRE

    Lancianese, Valerio

    2014-01-01

    Geochemical mapping is a valuable tool for the control of territory that can be used not only in the identification of mineral resources and geological, agricultural and forestry studies but also in the monitoring of natural resources by giving solutions to environmental and economic problems. Stream sediments are widely used in the sampling campaigns carried out by the world's governments and research groups for their characteristics of broad representativeness of rocks and soils, for ease o...