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Sample records for tong makoto suzuki

  1. STOTEN2016 Tong data

    Data.gov (United States)

    U.S. Environmental Protection Agency — CTAG model inputs and outputs. This dataset is associated with the following publication: Tong, Z., R. Baldauf , V. Isakov , P.J. Deshmukh, and M. Zhang. Roadside...

  2. Tutvustatakse Suzuki meetodit

    Index Scriptorium Estoniae

    2001-01-01

    Jaapanlase Scinichi Suzuki (1898-1991) meetod rajaneb põhimõttel, et kõigil on sünnihetkest alates teatud võimekus omandada mitmesuguseid oskusi, mida saab arendada selleks loodud soodsas keskkonnas. Tema meetod on kasutusel muusikainstrumentide õpetamisel, koolieelikute muusikatundides ning üldainete õpetamisel. 2001.a. märtsis külastab Eestit ja annab kontserte grupp USA Capitali Ülikooli suzukiõpilasi, Kontsertide ajakava

  3. Autobiography: Kinuko Suzuki, MD.

    Science.gov (United States)

    Healy, Eileen

    2014-02-01

    The following reminiscence by Kinuko Suzuki is the 9th autobiography in a series published in the Journal of Neuropathology and Experimental Neurology. These have been solicited from senior members of the neuropathology community who have been noted leaders and contributors to neuroscience and to the American Association of Neuropathologists (AANP) and have a historical perspective of the importance of neuropathology in diagnosis, education, and research. It is hoped that this series will entertain, enlighten, and present members of the AANP with a better sense of the legacy that we have inherited, as well as reintroduce our respected neuroscientists as humans having interesting lives filled with joys and sorrows and allowing them to present their lives in their own words.MNH, RAS.

  4. Means for attaching remote handling tongs

    International Nuclear Information System (INIS)

    Kearney, A.S.

    1982-01-01

    A remote handling tong has a replaceable slave head assembly provided with a spring biased latch which engages a recess in a barrel member of the tong. The latch bolt extends transverse to the barrel member, and has studs which project at each end beyond the body of the slave head assembly so as to engage respective linear cam surfaces at a station for parking the slave head assembly. (author)

  5. 21 CFR 882.5960 - Skull tongs for traction.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Skull tongs for traction. 882.5960 Section 882...) MEDICAL DEVICES NEUROLOGICAL DEVICES Neurological Therapeutic Devices § 882.5960 Skull tongs for traction. (a) Identification. Skull tongs for traction is an instrument used to immobilize a patient with a...

  6. Nucleation phenomena at Suzuki phases

    International Nuclear Information System (INIS)

    Acosta-Najarro, D.; Jose Y, M.

    1982-01-01

    Crystal of NaCl doped with Mn present regions with an increase in nucleation densities when observed by surface gold decoration; this increase is related to the nucleation of the Suzuki phases which are induced by cooling of the crystal matrix. Calculations based on atomistic nucleation theory are developed to explain the increased nucleation density. Experiments were made to compare with the theoretical results. In particular the density of nuclei was measured as a function of the rate or arrival of atoms to the surface. Therefore, the changes in the nucleation densities are explained in terms of change in migration energies between the Suzuki phase and the NaCl matrix excluding the possibility of nucleation induced by point defects. (author)

  7. Master-slave tele-tongs

    International Nuclear Information System (INIS)

    1992-05-01

    In a 'hot laboratory', manipulation is concerned with mechanical devices, controlled by a human operator and used to move or manipulate radioactive objects without direct contact. Master-slave Manipulators and Tele-tongs are devices permitting a worker on one side of the shield of a 'hotcell' or a 'gloves-box', to carry out safe laboratory operations, with radioactive materials on the other side. This instrument is used mainly for remote-manipulation purposes, that is, to handle elements, substances or equipment across a protective wall. A typical example of its use is the fractioning of radioisotopes (for medical and agricultural purposes), or the handling of toxic substances, the fractioning and/or mixing of noxious components constituting a health hazard for operators, etc. Mechanic-type manipulator and tongs usually operated in pairs, endowed with a high level of sensitivity which enables the operator, duly protected, to perform what would otherwise be hazardous and delicate tasks. INVAP manipulators are suitable for all king of installations with 'hot-cells' or 'gloves-box'. INVAP manipulators were developed to meet the problem of introducing it through the shielding wall of the 'hotcells' or 'gloves-box', without violating shielding integrity. To prevent any possibility of contamination, the telemanipulator has been lined with an airtight sheath or booting, also especially developed by INVAP for this instrument. Moreover, it has developed a special set of tools for booting- changing under perfectly safe conditions

  8. Nanocatalysts for Suzuki cross-coupling reactions

    KAUST Repository

    Fihri, Aziz; Bouhrara, Mohamed; Nekoueishahraki, Bijan; Basset, Jean-Marie; Polshettiwar, Vivek

    2011-01-01

    This critical review deals with the applications of nanocatalysts in Suzuki coupling reactions, a field that has attracted immense interest in the chemical, materials and industrial communities. We intend to present a broad overview of nanocatalysts

  9. Nanocatalysts for Suzuki cross-coupling reactions

    KAUST Repository

    Fihri, Aziz

    2011-01-01

    This critical review deals with the applications of nanocatalysts in Suzuki coupling reactions, a field that has attracted immense interest in the chemical, materials and industrial communities. We intend to present a broad overview of nanocatalysts for Suzuki coupling reactions with an emphasis on their performance, stability and reusability. We begin the review with a discussion on the importance of Suzuki cross-coupling reactions, and we then discuss fundamental aspects of nanocatalysis, such as the effects of catalyst size and shape. Next, we turn to the core focus of this review: the synthesis, advantages and disadvantages of nanocatalysts for Suzuki coupling reactions. We begin with various nanocatalysts that are based on conventional supports, such as high surface silica, carbon nanotubes, polymers, metal oxides and double hydroxides. Thereafter, we reviewed nanocatalysts based on non-conventional supports, such as dendrimers, cyclodextrin and magnetic nanomaterials. Finally, we discuss nanocatalyst systems that are based on non-conventional media, i.e., fluorous media and ionic liquids, for use in Suzuki reactions. At the end of this review, we summarise the significance of nanocatalysts, their impacts on conventional catalysis and perspectives for further developments of Suzuki cross-coupling reactions (131 references). © 2011 The Royal Society of Chemistry.

  10. Suzuki ja Szilvay : meetodist ja individuaalsusest / Lembi Mets

    Index Scriptorium Estoniae

    Mets, Lembi

    2000-01-01

    23. ja 24. apr. esines Tallinnas ans. Helsingin Juniorijousten F-avain-sello-bassoryhmä. 3. mail esines Tallinnas keelpilliõpilaste orkester Suzuki Nordic String. Suzuki ja Szilvayde muusikaõpetuse meetoditest, nende erinevustest, kasutamisvõimalustest Eestis

  11. Powerful Learning Experiences and Suzuki Music Teachers

    Science.gov (United States)

    Reuning-Hummel, Carrie; Meyer, Allison; Rowland, Gordon

    2016-01-01

    Powerful Learning Experiences (PLEs) of Suzuki music teachers were examined in this fifth study in a series. The definition of a PLE is: "Experiences that stand out in memory because of their high quality, their impact on one's thoughts and actions over time, and their transfer to a wide range of contexts and circumstances." Ten…

  12. Jing Tong Yu Shu , a traditional Chinese medicine, suppresses IL ...

    African Journals Online (AJOL)

    Purpose: To evaluate the effect of a traditional Chinese medicine, Jing Tong Yu Shu (JTYS) on endometriosis in a rat surgical model. Methods: Endometriosis was induced in 40 female rats. The rats were randomly divided into 4 groups: three JTYS groups given different doses of the drug, and a saline group. After four ...

  13. Kazama-Suzuki models as shifted bosonic lattices

    International Nuclear Information System (INIS)

    Buturovic, E.

    1992-01-01

    Some Kazama-Suzuki models admit a realization in terms of free bosons defined on a lattice. A criterion for such a realization and its construction are presented. Some examples are worked out. (orig.)

  14. Insights into the "pair of sugar tongs" surface binding site in barley alpha-amylase isozymes and crystallization of appropriate sugar tongs mutants

    DEFF Research Database (Denmark)

    Tranier, S.; Deville, K.; Robert, X.

    2005-01-01

    of an additional surface binding site called a "pair of sugar tongs" due to the sugar capturing by Tyr380 which is situated in domain C of AMYL For the first time, a biological role for the domain C was suggested as well as a hypothetical explanation of enzymatic differences between the two barley a......-amylase isozymes. However, no sugar was bound at the "sugar tongs" site in the AMY2/acarbose complex. Comparative studies of this domain on the basis of sequence, secondary structure and spatial organization allow to propose factors needed for such a site. One of the most obvious is the replacement of Ser378(AMY1......, surface plasmon resonance sugar binding experiments have proven unambiguously that this residue cannot totally explain the lack of the "pair of sugar tongs" and other tracks must be studied as, for example, the differences in orientation of Asp381 and the critical role of His395, both good candidates...

  15. Fermented Chinese formula Shuan-Tong-Ling attenuates ischemic stroke by inhibiting inflammation and apoptosis

    Directory of Open Access Journals (Sweden)

    Zhi-gang Mei

    2017-01-01

    Full Text Available The fermented Chinese formula Shuan-Tong-Ling is composed of radix puerariae (Gegen, salvia miltiorrhiza (Danshen, radix curcuma (Jianghuang, hawthorn (Shanzha, salvia chinensis (Shijianchuan, sinapis alba (Baijiezi, astragalus (Huangqi, panax japonicas (Zhujieshen, atractylodes macrocephala koidz (Baizhu, radix paeoniae alba (Baishao, bupleurum (Chaihu, chrysanthemum (Juhua, rhizoma cyperi (Xiangfu and gastrodin (Tianma, whose aqueous extract was fermented with lactobacillus, bacillus aceticus and saccharomycetes. Shuan-Tong-Ling is a formula used to treat brain diseases including ischemic stroke, migraine, and vascular dementia. Shuan-Tong-Ling attenuated H2O2-induced oxidative stress in rat microvascular endothelial cells. However, the potential mechanism involved in these effects is poorly understood. Rats were intragastrically treated with 5.7 or 17.2 mL/kg Shuan-Tong-Ling for 7 days before middle cerebral artery occlusion was induced. The results indicated Shuan-Tong-Ling had a cerebral protective effect by reducing infarct volume and increasing neurological scores. Shuan-Tong-Ling also decreased tumor necrosis factor-α and interleukin-1β levels in the hippocampus on the ischemic side. In addition, Shuan-Tong-Ling upregulated the expression of SIRT1 and Bcl-2 and downregulated the expression of acetylated-protein 53 and Bax. Injection of 5 mg/kg silent information regulator 1 (SIRT1 inhibitor EX527 into the subarachnoid space once every 2 days, four times, reversed the above changes. These results demonstrate that Shuan-Tong-Ling might benefit cerebral ischemia/reperfusion injury by reducing inflammation and apoptosis through activation of the SIRT1 signaling pathway.

  16. Defining According to Its Essence: An Analysis on the Concept of Tong Shi Education (General Education) in the Native Chinese Context

    Science.gov (United States)

    Lu, Yi; Xu, Yuan

    2018-01-01

    The authors review the concept of Tong Shi (Chinese characters omitted) in ancient Chinese philosophical texts, illustrate the Chinese cultural attributes unique to the characters Tong and Shi, and confirm that the name and essence of Tong Shi Education has a clear directivity and irreplaceable coverage to university general education in…

  17. Rap van tong, scherp van pen. Literaire discussiecultuur in Nederlandse praatjespamfletten (circa 1600-1750)

    NARCIS (Netherlands)

    Dingemanse, C.W.

    2008-01-01

    In the early modern period pamphlets constituted the most important medium to influence public opinion in the Netherlands. The thesis Rap van tong, scherp van pen (Glib tongues, sharp pens) focuses on the literary and rhetorical aspects of a remarkable type of pamphlet called praatje (small-talk),

  18. Groei en gedrag van schelpdieren in vijverteelt, samenvattend eindrapport Zeeuwse tong werkpakket 2

    NARCIS (Netherlands)

    Smaal, A.C.; Jansen, H.M.; Kamermans, P.; Schellekens, T.

    2014-01-01

    De binnendijkse kweek van schelpdieren en micro-algen is in het kader van het project Zeeuwse Tong onderzocht en uitgetest op verschillende schaalniveaus. In de pilots is op praktijkschaal getest wat er nodig is voor een commercieel haalbare productie. In één van de pilots (Colijnsplaat) zijn de

  19. Jing Tong Yu Shu, a traditional Chinese medicine, suppresses IL-1β ...

    African Journals Online (AJOL)

    Zhang et al. 2953. Tropical ... Purpose: To evaluate the effect of a traditional Chinese medicine, Jing Tong Yu Shu (JTYS) on endometriosis in a ..... Flower A, Liu JP, Chen S, Lewith G, Little P. Chinese ... Mol Hum Reprod 2000; 6: 269-275. 18.

  20. Gear and survey efficiency of patent tongs for oyster populations on restoration reefs.

    Directory of Open Access Journals (Sweden)

    David M Schulte

    Full Text Available Surveys of restored oyster reefs need to produce accurate population estimates to assess the efficacy of restoration. Due to the complex structure of subtidal oyster reefs, one effective and efficient means to sample is by patent tongs, rather than SCUBA, dredges, or bottom cores. Restored reefs vary in relief and oyster density, either of which could affect survey efficiency. This study is the first to evaluate gear (the first full grab and survey (which includes selecting a specific half portion of the first grab for further processing efficiencies of hand-operated patent tongs as a function of reef height and oyster density on subtidal restoration reefs. In the Great Wicomico River, a tributary of lower Chesapeake Bay, restored reefs of high- and low-relief (25-45 cm, and 8-12 cm, respectively were constructed throughout the river as the first large-scale oyster sanctuary reef restoration effort (sanctuary acreage > 20 ha at one site in Chesapeake Bay. We designed a metal frame to guide a non-hydraulic mechanical patent tong repeatedly into the same plot on a restored reef until all oysters within the grab area were captured. Full capture was verified by an underwater remotely-operated vehicle. Samples (n = 19 were taken on nine different reefs, including five low- (n = 8 and four high-relief reefs (n = 11, over a two-year period. The gear efficiency of the patent tong was estimated to be 76% (± 5% standard error, whereas survey efficiency increased to 81% (± 10% due to processing. Neither efficiency differed significantly between young-of-the-year oysters (spat and adults, high- and low-relief reefs, or years. As this type of patent tong is a common and cost-effective tool to evaluate oyster restoration projects as well as population density on fished habitat, knowing the gear and survey efficiencies allows for accurate and precise population estimates.

  1. Gear and survey efficiency of patent tongs for oyster populations on restoration reefs.

    Science.gov (United States)

    Schulte, David M; Lipcius, Romuald N; Burke, Russell P

    2018-01-01

    Surveys of restored oyster reefs need to produce accurate population estimates to assess the efficacy of restoration. Due to the complex structure of subtidal oyster reefs, one effective and efficient means to sample is by patent tongs, rather than SCUBA, dredges, or bottom cores. Restored reefs vary in relief and oyster density, either of which could affect survey efficiency. This study is the first to evaluate gear (the first full grab) and survey (which includes selecting a specific half portion of the first grab for further processing) efficiencies of hand-operated patent tongs as a function of reef height and oyster density on subtidal restoration reefs. In the Great Wicomico River, a tributary of lower Chesapeake Bay, restored reefs of high- and low-relief (25-45 cm, and 8-12 cm, respectively) were constructed throughout the river as the first large-scale oyster sanctuary reef restoration effort (sanctuary acreage > 20 ha at one site) in Chesapeake Bay. We designed a metal frame to guide a non-hydraulic mechanical patent tong repeatedly into the same plot on a restored reef until all oysters within the grab area were captured. Full capture was verified by an underwater remotely-operated vehicle. Samples (n = 19) were taken on nine different reefs, including five low- (n = 8) and four high-relief reefs (n = 11), over a two-year period. The gear efficiency of the patent tong was estimated to be 76% (± 5% standard error), whereas survey efficiency increased to 81% (± 10%) due to processing. Neither efficiency differed significantly between young-of-the-year oysters (spat) and adults, high- and low-relief reefs, or years. As this type of patent tong is a common and cost-effective tool to evaluate oyster restoration projects as well as population density on fished habitat, knowing the gear and survey efficiencies allows for accurate and precise population estimates.

  2. Grassmannian topological Kazama-Suzuki models and cohomology

    International Nuclear Information System (INIS)

    Blau, M.; Hussain, F.; Thompson, G.

    1995-10-01

    We investigate in detail the topological gauged Wess-Zumino-Witten models describing topological Kazama-Suzuki models based on complex Grassmannians. We show that there is a topological sector in which the ring of observables (constructed from the Grassmann odd scalars of the theory) coincides with the classical cohomology ring of the Grassmanian for all values of the level k. We also analyze the general ring structure of bosonic correlation functions, uncovering a whole hierarchy of level-rank relations (including the standard level-rank duality) among models based on different Grassmannians. Using the previously established localization of the topological Kazama-Suzuki model to an Abelian topological field theory, we reduce the correlators to finite-dimensional purely algebraic expressions. As an application, these are evaluated explicitly for the CP(2) model at level k and shown for all k to coincide with the cohomological intersection numbers of the two-plane Grassmannian G(2,K + 2), thus realizing the level-rank duality between this model and the G(2, k + 2) model at level one. (author). 28 refs

  3. Suzuki-Miyaura cross-coupling reactions in aqueous media: Green and sustainable syntheses of biaryls

    KAUST Repository

    Polshettiwar, Vivek; Decottignies, Audrey; Len, Christophe; Fihri, Aziz

    2010-01-01

    Carbon-carbon cross-coupling reactions are among the most important processes in organic chemistry, and Suzuki-Miyaura reactions are among the most widely used protocols for the formation of carbon-carbon bonds. These reactions are generally

  4. Retraction notice to “Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer” [Cancer Lett. 242 (2) (2006) 222–230]. Makoto Suzuki, Hisayuki Shigematsu, Narayan Shivapurkar, Jyotsna Reddy, Kuniharu Miyajima, Takao Takahashi, Adi F. Gazdar, Eugene P. Frenke.

    Science.gov (United States)

    2015-04-28

    Available online . This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the first author, who accepts responsibility. Following an internal review at the UT Southwestern Medical Center in Dallas, evidence has been found of improper manipulation and duplication of Figure 1 in this article.

  5. Effects of Shuang Wuzhen Tong Capsule on acute toxicity of mice caused by swelling and auricular dimethylbenzene

    Science.gov (United States)

    Hao, Shaojun; Sun, Youshu; Guo, Junyi; Chen, Weiliang; Wang, Hongyu; Sun, Jianhua; Guan, Zhijiang; Zhang, Zhengchen; Wang, Fang

    2018-04-01

    To observe the effect of Shuang Wuzhen Tong Capsule on acute toxicity of mice caused by swelling and auricular dimethylbenzene. 40 rats, weighing 18 ˜ 22G, half male and half female. Shuang Wuzhen Tong Capsule maximum concentration maximum volume to mice for 1 days by gavage for 1 times, for 7 consecutive days, to observe the situation of animal death, the maximum tolerance; the other 50 mice, were divided into 5 groups, were fed with Shuang Wuzhen Tong capsule suspension, Jingfukang granule suspension and the same volume 0.5%CMC. No death in 7 days. After death animal autopsy, heart, liver, spleen, lung, kidney, brain, stomach, intestine and no important organ obvious bleeding, hyperemia and edema, exudation, ulcer, perforation, pleural, peritoneal, pericardial cavity without effusion. Shuang Wuzhen Tong Capsule group and Jingfukang granule group could obviously reduce the xylene induced swelling of mouse ear, ear swelling degree decreased significantly (P<0.01). Shuang Wuzhen Tong Capsule has no obvious acute toxicity, anti-inflammatory effects.

  6. A Randomized Controlled Trial of Tong Len Meditation Practice in Cancer Patients: Evaluation of a Distant Psychological Healing Effect.

    Science.gov (United States)

    Pagliaro, Gioacchino; Pandolfi, Paolo; Collina, Natalina; Frezza, Giovanni; Brandes, Alba; Galli, Margherita; Avventuroso, Federica Marzocchi; De Lisio, Sara; Musti, Muriel Assunta; Franceschi, Enrico; Esposti, Roberta Degli; Lombardo, Laura; Cavallo, Giovanna; Di Battista, Monica; Rimondini, Simonetta; Poggi, Rosalba; Susini, Cinzia; Renzi, Rina; Marconi, Linda

    2016-01-01

    Tong Len meditation is an important therapeutic tool in the Tibetan medicine, and it can be used for self-healing and/or to heal others. Currently, in the West, there is no scientific study concerning the efficacy of a Tong Len distant healing effect on psychological disorders in cancer patients. To evaluate a distant healing effect of Tong Len meditation on stress, anxiety, depression, fatigue, and self-perceived quality of life in cancer patients. These psychological objectives were chosen as a consequence of the limited scientific literature of present day. We performed a double-blind randomized controlled trial on 103 cancer patients with tumors. Overall, 12 meditators used Tong Len in aid of 52 patients randomly selected as experimental group, while the remaining 51 patients constituted the control group. Patients and meditators did not know each other. All patients completed profile of mood states (POMS) and European Quality of Life-5 dimensions (EQ-5D) questionnaires before treatment (T0), after two (T1) and three months of treatment (T2), and one month after treatment cessation (T3). With regard to the parameters related to depression, a statistically significant improvement (P = .003) was observed in the treatment group compared to controls. On the other hand, the vigor/activity parameter saw significant improvements in the control group (P = .009). Both groups exhibited significant improvements in the other factors assessed in the POMS and EQ-5D questionnaires. This study did not provide sufficient evidence supporting an efficacy of Tong Len meditation in distant psychological healing as compared to a control condition. The research highlighted some psychological improvements through Tong Len distant meditation in a group of patients unknown to meditators. Therefore, the enhancement detected in most parameters in both treatment and control groups raises interest on in-depth analysis and evaluation of distant meditation on cancer patients to mitigate

  7. Attention and Perseverance Behaviors of PreSchool Children Enrolled in Suzuki Violin Lessons and Other Activities.

    Science.gov (United States)

    Scott, Laurie

    1992-01-01

    Reports on a study of attention span and persevering behaviors of preschool children. Finds the Suzuki Method of violin instruction is associated with longer attention spans and more persevering behaviors than creative movement instruction or other preschool programs. Concludes that teachers prefer the Suzuki Method's approach to other forms of…

  8. Discovering Green, Aqueous Suzuki Coupling Reactions: Synthesis of Ethyl (4-Phenylphenyl)Acetate, a Biaryl with Anti-Arthritic Potential

    Science.gov (United States)

    Costa, Nancy E.; Pelotte, Andrea L.; Simard, Joseph M.; Syvinski, Christopher A.; Deveau, Amy M.

    2012-01-01

    Suzuki couplings are powerful chemical reactions commonly employed in academic and industrial research settings to generate functionalized biaryls. We have developed and implemented a discovery-based, microscale experiment for the undergraduate organic chemistry laboratory that explores green Suzuki coupling using water as the primary solvent.…

  9. Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling in a Green Alcohol Solvent for an Undergraduate Organic Chemistry Laboratory

    Science.gov (United States)

    Hie, Liana; Chang, Jonah J.; Garg, Neil K.

    2015-01-01

    A modern undergraduate organic chemistry laboratory experiment involving the Suzuki-Miyaura coupling is reported. Although Suzuki-Miyaura couplings typically employ palladium catalysts in environmentally harmful solvents, this experiment features the use of inexpensive nickel catalysis, in addition to a "green" alcohol solvent. The…

  10. Palladium supported on natural phosphate: Catalyst for Suzuki coupling reactions in water

    KAUST Repository

    Hassine, Ayoub

    2013-01-01

    The Suzuki-Miyaura coupling reaction is one of the most important synthetic catalytic reactions developed in the 20th century. However, the use of toxic organic solvents for this reaction still poses a scientific challenge and is an aspect of economical and ecological relevance. The use of water as a reaction medium overcomes this issue. In the present work, we described efficient Suzuki coupling reactions in water, without any phase transfer reagents and it is possible to couple challenging substrates like aryl chlorides. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers. © 2012 Elsevier B.V.

  11. Suzuki-Miyaura cross-coupling reactions in aqueous media: Green and sustainable syntheses of biaryls

    KAUST Repository

    Polshettiwar, Vivek

    2010-02-28

    Carbon-carbon cross-coupling reactions are among the most important processes in organic chemistry, and Suzuki-Miyaura reactions are among the most widely used protocols for the formation of carbon-carbon bonds. These reactions are generally catalyzed by soluble palladium complexes with various ligands. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance. This Review will summarize various recently developed significant methods by which the Suzuki-Miyaura coupling was conducted in aqueous media, and analyzes if they are "real green" protocols. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Suzuki-Miyaura cross-coupling reactions in aqueous media: green and sustainable syntheses of biaryls.

    Science.gov (United States)

    Polshettiwar, Vivek; Decottignies, Audrey; Len, Christophe; Fihri, Aziz

    2010-05-25

    Carbon-carbon cross-coupling reactions are among the most important processes in organic chemistry, and Suzuki-Miyaura reactions are among the most widely used protocols for the formation of carbon-carbon bonds. These reactions are generally catalyzed by soluble palladium complexes with various ligands. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance. This Review will summarize various recently developed significant methods by which the Suzuki-Miyaura coupling was conducted in aqueous media, and analyzes if they are "real green" protocols.

  13. Positive effect of Chang Run Tong on colonic remodeling in streptozotocin-induced diabetic rats and mechanisms involved

    DEFF Research Database (Denmark)

    Zhao, Jingbo; Sha, Hong; Gregersen, Hans

    2015-01-01

    Objective: It has been documented that the Chinese medicine Chang Run Tong (CRT) has a positive effect on constipation which is a prominent symptom in diabetic patients. This present study investigated the effect and the possible mechanism of CRT on colonic remodeling in streptozotocin (STZ...

  14. Effect of Chang Run Tong on the Biomechanical and Morphometric Remodeling of Colon and Rectum in STZ Induced Diabetic Rats

    DEFF Research Database (Denmark)

    Sha, Hong; Zhao, Dong; Zhao, Jingbo

    2013-01-01

    The present study investigates the effect of Chang Run Tong (CRT) on the biomechanical and morphometrical remodeling of colon and rectum in streptozotocin-induced diabetic rats. The colonic and rectal segments were obtained from diabetic (DM), CRT-treated diabetic (T1, high dosage: 50 g/kg/day; T2...

  15. Facile palladium catalyzed Suzuki-Miyaura coupling in air and water at ambient temperature

    KAUST Repository

    Marziale, Alexander N.; Faul, Stefan Holger; Reiner, Thomas; Schneider, Sven; Eppinger, Jö rg

    2010-01-01

    A new palladacyclic catalyst yields high activities in aqueous Suzuki-Miyaura coupling at room temperature. Using an optimized protocol, a broad range of products can be isolated in good to excellent yields and high purity by simple filtration. © 2010 The Royal Society of Chemistry.

  16. The Conservation of Rhythm in Suzuki Violin Students: A Task Validation Study.

    Science.gov (United States)

    Nelson, David J.

    1984-01-01

    Twenty Suzuki violin students between four and eight years old were individually administered an author-designed rhythmic task and a series of standardized tasks that measured area and length conservation. The students' prior training was found to be less of a factor in rhythmic conservation than were age and area-length conservation. (Author/RM)

  17. Parental Involvement in the Musical Education of Violin Students: Suzuki and "Traditional" Approaches Compared

    Science.gov (United States)

    Bugeja, Clare

    2009-01-01

    This article investigates parental involvement in the musical education of violin students and the changing role of the parents' across the learning process. Two contexts were compared, one emphasising the Suzuki methodology and the other a "traditional" approach. Students learning "traditionally" are typically taught note reading from the…

  18. 'Click' dendritic phosphines: design, synthesis, application in Suzuki coupling, and recycling by nanofiltration

    NARCIS (Netherlands)

    Janssen, M.C.C.; Vogt, D.; Müller, C.

    2009-01-01

    A new synthetic route towards stable molecular-weight enlarged monodentate phosphine ligands via click chemistry was developed. These ligands were applied in the Pd-catalyzed Suzuki-Miyaura coupling of aryl halides and phenyl boronic acid. The supported systems show very similar activities compared

  19. Microwave-Assisted Synthesis of 5-Phenyl-2-Hydroxyacetophenone Derivatives by a Green Suzuki Coupling Reaction

    Science.gov (United States)

    Soares, Pedro; Fernandes, Carlos; Chavarria, Daniel; Borges, Fernanda

    2015-01-01

    In recent years, the use of boron-containing reagents in palladium-assisted C-C coupling reactions (the Suzuki reaction) has gained prominence due to the vast array of reagents commercially available. Consequently, the generation of carbon-carbon bonds, namely of functionalized biphenyl systems, is at present considered the backbone of organic…

  20. Learning with Sound Recordings: A History of Suzuki's Mediated Pedagogy

    Science.gov (United States)

    Thibeault, Matthew D.

    2018-01-01

    This article presents a history of mediated pedagogy in the Suzuki Method, the first widespread approach to learning an instrument in which sound recordings were central. Media are conceptualized as socially constituted: philosophical ideas, pedagogic practices, and cultural values that together form a contingent and changing technological…

  1. 76 FR 4991 - Petition for Exemption From the Vehicle Theft Prevention Standard; Suzuki

    Science.gov (United States)

    2011-01-27

    ... From the Vehicle Theft Prevention Standard; Suzuki AGENCY: National Highway Traffic Safety... of the Kizashi vehicle line in accordance with 49 CFR part 543, Exemption from the Theft Prevention... vehicle theft as compliance with the parts-marking requirements of the 49 CFR part 541, Federal Motor...

  2. Ruphus-mediated Suzuki cross-coupling of secondary alkyl trifluoroborates

    NARCIS (Netherlands)

    Hoogenband, van den A.; Lange, J.H.M.; Terpstra, J.W.; Koch, M.; Visser, G.M.; Visser, de M.; Korstanje, T.J.; Jastrzebski, J.T.B.H.

    2008-01-01

    A Ruphos-mediated Suzuki cross-coupling between (hetero)aryl bromides and secondary alkyltrifluoroborates is described using palladium catalysis. The Ruphos ligand showed superior properties as compared to S-Phos in this type of reaction. This method constitutes a valuable extension to current

  3. Introducing Undergraduates to Research Using a Suzuki-Miyaura Cross-Coupling Organic Chemistry Miniproject

    Science.gov (United States)

    Oliveira, Deyvid G. M.; Rosa, Clarissa H.; Vargas, Bruna P.; Rosa, Diego S.; Silveira, Ma´rcia V.; de Moura, Neusa F.; Rosa, Gilber R.

    2015-01-01

    A five-week miniproject is described for an upper-division experimental organic chemistry course. The activities include synthesis of a phenylboronic acid via a Grignard reaction and its use in a Suzuki-Miyaura cross-coupling reaction. Technical skills and concepts normally presented in practical organic chemistry courses are covered, including…

  4. Uudised : TÜ Kammerkoor laulis Rootsis. Suzuki Nordic String Eestis. Vello Loogna sünnipäevakontsert / Valdur Liiv

    Index Scriptorium Estoniae

    Liiv, Valdur

    2000-01-01

    TÜ Kammerkoor esines ülestõusmispühadel Rootsi kirikutes. Põhjamaade laste keelpilliorkester esineb Eestis 1., 2. ja 3. mail. Lühidalt Suzuki pedagoogikast. V. Loogna 60. juubeli kontserdist 30. apr. Estonia kontserdisaalis

  5. Inhibitory effect of bofutsushosan (fang feng tong sheng san) on glucose transporter 5 function in vitro.

    Science.gov (United States)

    Gao, Shengli; Satsu, Hideo; Makino, Toshiaki

    2018-03-01

    Bofutsushosan (BTS; fang feng tong sheng san in Chinese) is a formula in traditional Japanese Kampo medicine and Chinese medicine comprising eighteen crude drugs, and is used to treat obesity and metabolic syndrome. Fructose is contained in refreshing beverages as high-fructose corn syrup, and is associated with obesity. Fructose is absorbed via glucose transporter 5 (GLUT5) in the intestine. Therefore, the inhibition of GLUT5 is considered to be a target of obesity drugs. We evaluated the inhibitory effects of BTS extract and its constituents on fructose uptake using Chinese hamster ovary K1 cells, i.e., cells stably expressing GLUT5. Boiled water extract of BTS significantly suppressed GLUT5 function in a concentration-dependent manner without cytotoxicities. Among 18 components of BTS, the boiled water extracts of the rhizome of Zingiber officinale, the root and rhizome of Saposhnikovia divaricata, and the root of Platycodon grandiflorum exhibited significant inhibitory effects on fructose uptake with IC 50 values of 314, 119 and 475 µg/ml, respectively. Among the constituents of the rhizome of Z. officinale extract, 6-gingerol significantly inhibited GLUT5 with an IC 50 value of 39 µM, while 6-shogaol exhibited a significant but weak inhibition on GLUT5 at 100 µM. One of the mechanisms of action of BTS may be the inhibition of fructose absorption in the intestine, and one of the active components of BTS is the rhizome of Z. officinale and 6-gingerol.

  6. Pengaruh Pelaksanaan Pelatihan terhadap Kinerja Karyawan PT. Sejahtera Buana Trada Cabang Pekanbaru (Kasus Karyawan Bagian Marketing Dealer Suzuki Mobil)

    OpenAIRE

    Juwita, Ratna; ", Suryalena

    2016-01-01

    The purpose of this study was to determine the effect of exercise training on the performance of employees of PT. Sejahtera Buana Trada Branch Pekanbaru (Case Employee Suzuki Car Dealer Marketing Division). This research was conducted at PT. Sejahtera Buana Trada Branch Pekanbaru (Suzuki Car Dealer) located in the SM. Amin Number.89 Simpang Baru Tampan. In this research method used is a method of statistical tests with SPSS, where samples were used that employee marketing division of PT. Seja...

  7. Highly Efficient Synthesis of 2-Aryl-3-methoxyacrylates via Suzuki-Miyaura Coupling Reaction

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyung Ho; Lee, Chun Ho; Song, Young Seob; Park, No Kyun; Kim, Bum Tae; Heo, Jung Nyoung [Korea Research Institute of Chemical Technology, Daejeon (Korea, Republic of)

    2006-02-15

    We have developed a highly efficient and convergent synthesis of 2-aryl-3-methoxyacrylates via the Suzuki-Miyaura coupling reaction of α-iodo-β-methoxy-acrylate with arylboronic acids. The biological activities of 2-aryl-3-methoxyacrylate derivatives will be reported in due course. The Suzuki-Miyaura coupling reaction provides a convenient access to the carbon-carbon bond formation with high efficiency. Recently, a number of 2-aryl-3-methoxy-acrylates served as a key scaffold for the development of biologically active pharmaceuticals and agrochemicals. Especially, the discovery of the naturally-occurring fungicides, such as strobilurin A and oudemansin A, possessing a β-methoxyacrylate moiety was immediately seized great attention by industrial research groups to open a new era of the strobilurin family including azoxy-strobin and picoxystrobin.

  8. Optical trapping via guided resonance modes in a Slot-Suzuki-phase photonic crystal lattice.

    Science.gov (United States)

    Ma, Jing; Martínez, Luis Javier; Povinelli, Michelle L

    2012-03-12

    A novel photonic crystal lattice is proposed for trapping a two-dimensional array of particles. The lattice is created by introducing a rectangular slot in each unit cell of the Suzuki-Phase lattice to enhance the light confinement of guided resonance modes. Large quality factors on the order of 10⁵ are predicted in the lattice. A significant decrease of the optical power required for optical trapping can be achieved compared to our previous design.

  9. Fibrous nano-silica (KCC-1)-supported palladium catalyst: Suzuki coupling reactions under sustainable conditions

    KAUST Repository

    Fihri, Aziz; Cha, Dong Kyu; Bouhrara, Mohamed; Al Mana, Noor; Polshettiwar, Vivek

    2011-01-01

    Noble amines recycled: Fibrous high-surface-area nano-silica functionalized with aminopropyl groups and loaded with well-dispersed Pd nanoparticles is evaluated for the Suzuki coupling of aromatic halides. It is active for the reaction of a range of aryl bromides and iodides as well as chlorides with aryl boronic acids in good to excellent yields. The catalyst can be recovered and reused for a number of cycles with negligible loss in activity. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Supported palladium nanoparticles synthesized by living plants as a catalyst for Suzuki-Miyaura reactions.

    Directory of Open Access Journals (Sweden)

    Helen L Parker

    Full Text Available The metal accumulating ability of plants has previously been used to capture metal contaminants from the environment; however, the full potential of this process is yet to be realized. Herein, the first use of living plants to recover palladium and produce catalytically active palladium nanoparticles is reported. This process eliminates the necessity for nanoparticle extraction from the plant and reduces the number of production steps compared to traditional catalyst palladium on carbon. These heterogeneous plant catalysts have demonstrated high catalytic activity in Suzuki coupling reactions between phenylboronic acid and a range of aryl halides containing iodo-, bromo- and chloro- moieties.

  11. Fibrous nano-silica (KCC-1)-supported palladium catalyst: Suzuki coupling reactions under sustainable conditions

    KAUST Repository

    Fihri, Aziz

    2011-11-15

    Noble amines recycled: Fibrous high-surface-area nano-silica functionalized with aminopropyl groups and loaded with well-dispersed Pd nanoparticles is evaluated for the Suzuki coupling of aromatic halides. It is active for the reaction of a range of aryl bromides and iodides as well as chlorides with aryl boronic acids in good to excellent yields. The catalyst can be recovered and reused for a number of cycles with negligible loss in activity. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. A redescription of Zavrelia simantoneoa (Sasa, Suzuki and Sakai, 1998 comb. nov.

    Directory of Open Access Journals (Sweden)

    Tadashi Kobayashi

    2014-12-01

    Full Text Available Examination of the holotype of Micropsectra simantoneoa Sasa, Suzuki and Sakai, 1998 revealed that the species should be transferred to the genus Zavrelia. The male adult has hairy eyes, antennae with 10 flagellomeres, a costa ending proximal to the tip of M3+4, and a short and flattened superior volsella. This is the second Zavrelia species from Japan, and the 11th in the world.Article submitted 25. September 2014, accepted 16. October 2014, published 22. December 2014.

  13. Synthesis of new pyrrole–pyridine-based ligands using an in situ Suzuki coupling method

    Directory of Open Access Journals (Sweden)

    Matthias Böttger

    2012-07-01

    Full Text Available The compounds 6-(pyrrol-2-yl-2,2‘-bipyridine, 2-(pyrrol-2-yl-1,10-phenanthroline and 2-(2-(N-methylbenz[d,e]imidazole-6-(pyrrol-2-yl-pyridine were synthesized by using an in situ generated boronic acid for the Suzuki coupling. Crystals of the products could be grown and exhibited interesting structures by X-ray analysis, one of them showing a chain-like network with the adjacent molecules linked to each other via intermolecular N–H…N hydrogen bonds.

  14. Microwave-Assisted Synthesis of a MK2 Inhibitor by Suzuki-Miyaura Coupling for Study in Werner Syndrome Cells

    Directory of Open Access Journals (Sweden)

    Mark C. Bagley

    2015-06-01

    Full Text Available Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2 inhibitors to study accelerated aging in Werner syndrome (WS cells, including the cross-coupling of a 2-chloroquinoline with a 3-pyridinylboronic acid, the coupling of an aryl bromide with an indolylboronic acid and the reaction of a 3-amino-4-bromopyrazole with 4-carbamoylphenylboronic acid. In all of these processes, the Suzuki-Miyaura reaction was fast and relatively efficient using a palladium catalyst under microwave irradiation. The process was incorporated into a rapid 3-step microwave-assisted method for the synthesis of a MK2 inhibitor involving 3-aminopyrazole formation, pyrazole C-4 bromination using N-bromosuccinimide (NBS, and Suzuki-Miyaura cross-coupling of the pyrazolyl bromide with 4-carbamoylphenylboronic acid to give the target 4-arylpyrazole in 35% overall yield, suitable for study in WS cells.

  15. Natural phosphate-supported palladium: A highly efficient and recyclable catalyst for the suzuki-miyaura coupling under microwave irradiation

    KAUST Repository

    Hassine, Ayoub; Bouhrara, Mohamed; Sebti, Said; Solhy, Abderrahim; Mahfouz, Remi; Luart, Denis; Lene, Christophe; Fihri, Aziz

    2015-01-01

    This report explores Suzuki-Miyaura coupling under microwave irradiation, using a new generation of catalyst that is based on natural phosphate (NP) impregnated by palladium. This catalyst was prepared by the treatment of natural phosphate with bis(benzonitrile)palladium(II) chloride in acetone at room temperature. The catalyst displayed high catalytic activity for the Suzuki-Miyaura coupling of aryl bromides and chlorides with aryl boronic acids in pure water and with the use of microwave irradiation. The low-cost and availability of the solid support, mild reaction conditions, high yields of desired products, recyclability of the catalyst and short reaction times are the notable features of these methods.

  16. The Suzuki-Miyaura Cross-Coupling Reaction of Halogenated Aminopyrazoles: Method Development, Scope, and Mechanism of Dehalogenation Side Reaction.

    Science.gov (United States)

    Jedinák, Lukáš; Zátopková, Renáta; Zemánková, Hana; Šustková, Alena; Cankař, Petr

    2017-01-06

    The efficient Suzuki-Miyaura cross-coupling reaction of halogenated aminopyrazoles and their amides or ureas with a range of aryl, heteroaryl, and styryl boronic acids or esters has been developed. The method allowed incorporation of problematic substrates: aminopyrazoles bearing protected or unprotected pyrazole NH, as well as the free amino or N-amide group. Direct comparison of the chloro, bromo, and iodopyrazoles in the Suzuki-Miyaura reaction revealed that Br and Cl derivatives were superior to iodopyrazoles, as a result of reduced propensity to dehalogenation. Moreover, the mechanism and factors affecting the undesired dehalogenation side reaction were revealed.

  17. Synthesis and Suzuki Cross-Coupling Reactions of 2,6-Bis(trifluoromethyl)pyridine-4-boronic Acid Pinacol Ester

    KAUST Repository

    Batool, Farhat

    2016-11-18

    Iridium-catalyzed aromatic borylation provides quick one-step access to 2,6-bis(trifluoromethyl)pyridine-4-boronic acid pinacol ester. Suzuki couplings of this highly electron-deficient pyridine-4-boronic ester with various (hetero)aryl bromides was successfully carried out and the coupled products were obtained in 46–95% isolated yields. Double and triple Suzuki couplings, with dibromo- and tribromoarenes, respectively, were also achieved. Thus demonstrating that this pyridine-4-boronic ester can be a useful source for the installation of one of the strongest electron-withdrawing aromatic group in organic compounds. Copyright © 2016, Georg Thieme Verlag. All rights reserved.

  18. Suzuki-Miyaura cross-coupling coupling reactions with low catalyst loading: a green and sustainable protocol in pure water.

    Science.gov (United States)

    Fihri, Aziz; Luart, Denis; Len, Christophe; Solhy, Abderrahim; Chevrin, Carole; Polshettiwar, Vivek

    2011-04-07

    The Suzuki-Miyaura coupling reaction represents one of the most important synthetic transformations developed in the 20th century. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance, and benign water as a reaction medium was found to be highly effective to overcome some of these issues. In the present manuscript, we described Suzuki-Miyaura coupling reactions in neat water, without using any phase transfer reagent. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers and also able to couple challenging substrates like aryl chlorides. © The Royal Society of Chemistry 2011

  19. Natural phosphate-supported palladium: A highly efficient and recyclable catalyst for the suzuki-miyaura coupling under microwave irradiation

    KAUST Repository

    Hassine, Ayoub

    2015-01-19

    This report explores Suzuki-Miyaura coupling under microwave irradiation, using a new generation of catalyst that is based on natural phosphate (NP) impregnated by palladium. This catalyst was prepared by the treatment of natural phosphate with bis(benzonitrile)palladium(II) chloride in acetone at room temperature. The catalyst displayed high catalytic activity for the Suzuki-Miyaura coupling of aryl bromides and chlorides with aryl boronic acids in pure water and with the use of microwave irradiation. The low-cost and availability of the solid support, mild reaction conditions, high yields of desired products, recyclability of the catalyst and short reaction times are the notable features of these methods.

  20. Synthesis and Suzuki Cross-Coupling Reactions of 2,6-Bis(trifluoromethyl)pyridine-4-boronic Acid Pinacol Ester

    KAUST Repository

    Batool, Farhat; Emwas, Abdul-Hamid M.; Gao, Xin; Munawar, Munawar A.; Chotana, Ghayoor A.

    2016-01-01

    Iridium-catalyzed aromatic borylation provides quick one-step access to 2,6-bis(trifluoromethyl)pyridine-4-boronic acid pinacol ester. Suzuki couplings of this highly electron-deficient pyridine-4-boronic ester with various (hetero)aryl bromides was successfully carried out and the coupled products were obtained in 46–95% isolated yields. Double and triple Suzuki couplings, with dibromo- and tribromoarenes, respectively, were also achieved. Thus demonstrating that this pyridine-4-boronic ester can be a useful source for the installation of one of the strongest electron-withdrawing aromatic group in organic compounds. Copyright © 2016, Georg Thieme Verlag. All rights reserved.

  1. Suzuki-Miyaura cross-coupling coupling reactions with low catalyst loading: A green and sustainable protocol in pure water

    KAUST Repository

    Fihri, Aziz; Luart, Denis; Len, Christophe; Solhy, Abderrahim; Chevrin, Carole; Polshettiwar, Vivek

    2011-01-01

    The Suzuki-Miyaura coupling reaction represents one of the most important synthetic transformations developed in the 20th century. However, the use of toxic organic solvents remains a scientific challenge and an aspect of economical and ecological relevance, and benign water as a reaction medium was found to be highly effective to overcome some of these issues. In the present manuscript, we described Suzuki-Miyaura coupling reactions in neat water, without using any phase transfer reagent. Notably, this protocol also works with ultra-low loading of catalyst with high turnover numbers and also able to couple challenging substrates like aryl chlorides. © 2011 The Royal Society of Chemistry.

  2. Palladium nanoparticles as catalysts for reduction of Cr(VI) and Suzuki coupling reaction

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Lilan; Guo, Yali; Iqbal, Anam; Li, Bo; Deng, Min; Gong, Deyan; Liu, Weisheng; Qin, Wenwu, E-mail: qinww@lzu.edu.cn [Lanzhou University, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering (China)

    2017-04-15

    Herein, six kinds of PdNPs (including icosahedron, sphere, spindle, cube, rod, and wire) were synthesized via simple methods. The catalytic activities were investigated by the reduction reaction of Cr(VI) and Suzuki coupling reaction. Chemically synthesized morphologies of the six catalysis were characterized by transmission electron microscopy, field emission scanning electron microscopy, and X-ray diffraction, etc. Pd icosahedron shows a better catalytic property than other PdNPs with a rate constants 0.42 min{sup −1} for the reduction of Cr(VI). Moreover, the electrocatalyst shows that Pd icosahedron possesses a bigger surface area of 8.56 m{sup 2}/g than other nanoparticles, which is attributed to the better catalyst. The Pd icosahedron possesses a better catalytic property, attributing to the abundant exposed {111} facets with high activity on Pd icosahedron. The catalytic activities are closely related to the surface area with the following order: icosahedrons ≥ sphere > rod > spindle > cube > wire. The Pd icosahedron catalyst represents a strong activity for Suzuki coupling reaction as well, outweighting is 80%. The results reveal that Pd icosahedron acts as an efficient catalyst compared to other PdNPs (wire, rod, sphere, spindle, and cube).

  3. The Effect of Chang Run Tong on Biomechanical Colon Remodeling in STZ-Induced Type I Diabetic Rats - Is It Related to Advanced Glycation End Product Formation?

    DEFF Research Database (Denmark)

    Zhao, Jingbo; Gregersen, Hans

    2015-01-01

    BACKGROUND AND AIM: The Chinese medicine Chang Run Tong (CRT) effectively improved senile constipation in the clinics. The aims of the present study were to investigate the effect of CRT on colonic remodeling in streptozotocin (STZ) induced diabetic rats and to explore the mechanisms of the CRT...

  4. The Introduction of High-Throughput Experimentation Methods for Suzuki-Miyaura Coupling Reactions in University Education

    Science.gov (United States)

    Hoogenboom, Richard; Meier, Michael A. R.; Schubert, Ulrich S.

    2005-01-01

    A laboratory project permits for the discussion of the reaction mechanism of the Suzuki-Miyaura coupling reaction. The practical part of the project makes the students familiar with working under inert atmosphere but if the appropriate equipment for working under inert atmosphere is not available in a laboratory, novel catalysts that do not…

  5. Hexacationic Dendriphos ligands in the Pd-catalyzed Suzuki-Miyaura cross-coupling reaction: scope and mechanistic studies

    NARCIS (Netherlands)

    Snelders, D.J.M.; van Koten, G.; Klein Gebbink, R.J.M.

    2009-01-01

    The combination of Pd2dba3·CHCl3and hexacationic triarylphosphine-based Dendriphos ligands (1-3) leads to a highly active catalytic system in the Suzuki-Miyaura cross-coupling reaction. Under relatively mild reaction conditions, nonactivated aryl bromides and activated aryl chlorides can be coupled

  6. Suzuki coupling reactions catalyzed by poly(N-ethyl-4-vinylpyridinium bromide stabilized palladium nanoparticles in aqueous solution

    Directory of Open Access Journals (Sweden)

    2008-04-01

    Full Text Available InIn this work, it was investigated to use of poly(N-ethyl-4-vinylpyridinium bromide stabilized palladium nanoparticles in the Suzuki reaction between phenylboronic acid and aryl halides in aqueous solution. The nanoparticles were isolated and re-used several times with low loss of activity.

  7. Ligandless Suzuki-Miyaura reaction in neat water with or without native β-cyclodextrin as additive

    KAUST Repository

    Decottignies, Audrey

    2013-02-01

    Efficient green ligand-free Suzuki cross coupling in neat water was developed by using low loading of catalyst (0.5 mol%) in neat water in the presence or not of β-cyclodextrin (0.5 mol%) as additive at 25 C and 100 C respectively. © 2012 Elsevier B.V.

  8. Carbazole-based copolymers via direct arylation polymerization (DArP) for Suzuki-convergent polymer solar cell performance

    DEFF Research Database (Denmark)

    Gobalasingham, Nemal S.; Ekiz, Seyma; Pankow, Robert M.

    2017-01-01

    Although direct arylation polymerization (DArP) has recently emerged as an alternative to traditional cross-coupling methods like Suzuki polymerization, the evaluation of DArP polymers in practical applications like polymer solar cells (PSCs) is limited. Because even the presence of minute...

  9. Palladium on Carbon-Catalyzed Suzuki-Miyaura Coupling Reaction Using an Efficient and Continuous Flow System

    Directory of Open Access Journals (Sweden)

    Tomohiro Hattori

    2015-01-01

    Full Text Available The continuous flow Suzuki-Miyaura reaction between various haloarenes and arylboronic acids was successfully achieved within only ca. 20 s during the single-pass through a cartridge filled with palladium on carbon (Pd/C. No palladium leaching was observed in the collected reaction solution by atomic absorption spectrometry (detection limit: 1 ppm.

  10. A survey of food hygiene knowledge and attitudes among Chinese food handlers in Fong Song Tong district.

    Science.gov (United States)

    Tang, C H; Fong, U W

    2004-01-01

    The purpose of this study was to find out the knowledge and attitudes concerning food hygiene among Chinese food handlers in Fong Song Tong district, and to analyze the impact of variables on the degree of knowledge and attitudes. Face-to-face interviews were conducted within Chinese food handlers in Fong Song Tong district using a self-designed questionnaire, which contained food hygiene knowledge and attitudes. Main knowledge outcome measures included food handling, personal hygiene and legislation issues. Questionnaires were completed by 580 (72.0%) Chinese food handlers from 91% premises of the district. 71.2% Chinese food handlers could respond correctly to eight or more out of 11 knowledge questions and 1.4% respondents only achieved full scores of knowledge. Fully correct response of personal hygiene knowledge was statistically and significantly higher than food handling knowledge (phygiene education. Male respondents, age less than 30, secondary education or above, five years or more of working experience, or who had previously attended a health training within the last two years, generally performed better on the knowledge of food hygiene. Chinese food handlers working in the kitchen and owners' beliefs on 'cleaning the kitchen before getting off duty' was reasonable. Those with secondary education at least, or who had prior participation in a health training within the last two years would need more food hygiene knowledge than the people aged over 30 or who were the owners. It would be more motivated by changing the traditional training model, community-based education in an optimum situation, additional authoritative information, attitudes and intentions of learning on food hygiene.

  11. Study of NaCl:Mn2+ nanostructures in the Suzuki phase by optical spectroscopy and atomic force microscopy

    International Nuclear Information System (INIS)

    Mejía-Uriarte, E.V.; Kolokoltsev, O.; Navarrete Montesinos, M.; Camarillo, E.; Hernández A, J.; Murrieta S, H.

    2015-01-01

    NaCl:Mn 2+ nanostructures in the Suzuki phase have been studied by fluorescence (emission and excitation) spectroscopy and atomic force microscopy (AFM) as a function of temperature. The “as-grown” samples give rise to two broad emission bands that peak at 508 (green emission) and 610 nm (red emission). The excitation spectrum shows peaks at 227 nm and 232 nm for emission wavelengths at 508 nm and 610 nm, respectively. When the samples are heated continuously from room temperature up to 220 °C, the green emission (associated to the excitation peak at 227 nm) disappears at a temperature close to 120 °C, whilst only the red emission remains, which is characteristic of manganese ions. AFM images on the (0 0 1) surface (freshly cleaved) show several conformations of nanostructures, such as disks of 20–50 nm in diameter. Particularly, the images also reveal nanostructures with rectangular shape of ~280×160 nm 2 and ~6 nm height; these are present only in samples with green emission associated to the Suzuki phase. Then, the evidence suggests that this topographic configuration might be related to the interaction with the first neighbors and the next neighbors, according to the configuration that has been suggested for the Suzuki phase. - Highlights: • NaCl:Mn 2+ single crystals in the Suzuki phase contain rectangular nanostructures. • Double emission of manganese ions: green (508 nm) and red (610 nm) bands. • The excitation peak at 227 nm is attributed to rectangular nanostructures. • The green emission band associated to Suzuki phase is extinguished at 120 °C

  12. An efficient protocol for the palladium-catalysed Suzuki-Miyaura cross-coupling

    KAUST Repository

    Marziale, Alexander N.; Jantke, Dominik; Faul, Stefan Holger; Reiner, Thomas; Herdtweck, Eberhardt; Eppinger, Jö rg

    2011-01-01

    The palladacyclic catalyst precursor received by ortho-palladation of ([1,1′-biphenyl]-2-yloxy)diisopropyl-phosphine represents a highly active system for Suzuki-Miyaura cross-coupling reactions when used in neat water. An efficient, broadly applicable and sustainable aqueous protocol was developed using 2.5 eq. of Na2CO3 as base, allowing the reaction to be performed under air and at ambient temperature with Pd loadings of 0.04 mol%. Coupling products are obtained in high yields and excellent purity by simple filtration with no organic solvents needed throughout the whole reaction. A broad variety of functional groups are tolerated and a large number of substrates can be applied with this protocol. The crystal structure of the palladacyclic catalyst precursor is presented as well as investigations targeting the nature of catalyst activation and the active catalytic species. © 2011 The Royal Society of Chemistry.

  13. Preparation of Pd-Diimine@SBA-15 and Its Catalytic Performance for the Suzuki Coupling Reaction

    Directory of Open Access Journals (Sweden)

    Jiahuan Yu

    2016-11-01

    Full Text Available A highly efficient and stable Pd-diimine@SBA-15 catalyst was successfully prepared by immobilizing Pd onto diimine-functionalized mesoporous silica SBA-15. With the help of diimine functional groups grafted onto the SBA-15, Pd could be anchored on a support with high dispersion. Pd-diimine@SBA-15 catalyst exhibited excellent catalytic performance for the Suzuki coupling reaction of electronically diverse aryl halides and phenylboronic acid under mild conditions with an ultralow amount of Pd (0.05 mol % Pd. When the catalyst amount was increased, it could catalyze the coupling reaction of chlorinated aromatics with phenylboronic acid. Compared with the catalytic performances of Pd/SBA-15 and Pd-diimine@SiO2 catalysts, the Pd-diimine@SBA-15 catalyst exhibited higher hydrothermal stability and could be repeatedly used four times without a significant decrease of its catalytic activity.

  14. ESTUDIO DEL MODELO DE PROPAGACIÓN SUZUKI PARA REDES MÓVILES

    Directory of Open Access Journals (Sweden)

    Gina Sierra

    2013-12-01

    Full Text Available Este artículo presenta brevemente la teoría fundamental del Modelo Suzuki comúnmente usado para modelar la propagación en canales inalámbricos. El modelo toma en cuenta los efectos del sombreado y del multi-trayecto de manera simultánea. Además, se valida el modelo mediante una comparación estadística entre mediciones realizadas en el entorno real y simulaciones realizadas en MATLAB® a través de la generación de series de tiempo Suzuki distribuidas. Las mediciones se realizaron durante diez horas sobre la banda de frecuencias entre 850 MHz y 900 MHz. Con los datos obtenidos en medición durante los primeros cinco minutos, se caracterizó el canal inalámbrico para cada una de las frecuencias muestreadas calculando la media y desviación estándar de la señal recibida. Estos dos parámetros fueron introducidos como variables de entrada para la generación de las respectivas series de tiempo. Para cada frecuencia se realizaron simulaciones prediciendo los niveles de la señal que se obtendrían durante diez horas. Finalmente, se calculó el error cuadrático medio entre los valores medidos y los valores generados en simulación. Los resultados obtenidos demuestran que el modelo es válido como una herramienta de predicción de las características de propagación en comunicaciones móviles.

  15. Woman Survival in Chinese Feudal Patrilineal Society: An Analysis of Song Lian's Destiny in Qi Qie Chenqun By Su Tong

    Directory of Open Access Journals (Sweden)

    Xuc Lin

    2009-05-01

    Full Text Available Article depicted woman’s difficulties in maintaining her life as well as her aggressiveness in the patrilineal society in Chinese feudal time. Article analyzed Song Lian’s bad fate. She was the main character of qi qie chenqun novel, written by Su Tong. Article analysis consisted of three parts. The first part described Song Lian’s background of life and her becoming a mistress. The second part indicated Song Lian’s attacking behavior to other woman because of defending her life. His third part analyzed some causes that made Song Lian did not survive in life. It can be concluded that the fact, Song Lian is able to be survive but she decides to be a mistress caused by both personal and o social reasons. Song Lian’s attacking other woman is caused by her anger representing her unsuccessful life. Principally, Song Lian’s failure in the feudal life is caused by her unsuccessful in becoming a respected woman. If she had been a respected woman, she would have also competed with other women in achieving a better life.      

  16. Wen-Luo-Tong Prevents Glial Activation and Nociceptive Sensitization in a Rat Model of Oxaliplatin-Induced Neuropathic Pain.

    Science.gov (United States)

    Deng, Bo; Jia, Liqun; Pan, Lin; Song, Aiping; Wang, Yuanyuan; Tan, Huangying; Xiang, Qing; Yu, Lili; Ke, Dandan

    2016-01-01

    One of the main dose-limiting complications of the chemotherapeutic agent oxaliplatin (OXL) is painful neuropathy. Glial activation and nociceptive sensitization may be responsible for the mechanism of neuropathic pain. The Traditional Chinese Medicine (TCM) Wen-luo-tong (WLT) has been widely used in China to treat chemotherapy induced neuropathic pain. However, there is no study on the effects of WLT on spinal glial activation induced by OXL. In this study, a rat model of OXL-induced chronic neuropathic pain was established and WLT was administrated. Pain behavioral tests and morphometric examination of dorsal root ganglia (DRG) were conducted. Glial fibrillary acidic protein (GFAP) immunostaining was performed, glial activation was evaluated, and the excitatory neurotransmitter substance P (SP) and glial-derived proinflammatory cytokine tumor necrosis factor-α (TNF-α) were analyzed. WLT treatment alleviated OXL-induced mechanical allodynia and mechanical hyperalgesia. Changes in the somatic, nuclear, and nucleolar areas of neurons in DRG were prevented. In the spinal dorsal horn, hypertrophy and activation of GFAP-positive astrocytes were averted, and the level of GFAP mRNA decreased significantly. Additionally, TNF-α mRNA and protein levels decreased. Collectively, these results indicate that WLT reversed both glial activation in the spinal dorsal horn and nociceptive sensitization during OXL-induced chronic neuropathic pain in rats.

  17. The Development of Thung Fa Bot Weekend Market into Cultural Tourism Attraction in San Pa Tong District, Chiang Mai Province

    Directory of Open Access Journals (Sweden)

    Phuwanatwichit Thongchai

    2014-01-01

    Full Text Available This study aimed to investigate for the socio-cultural and economic context, along with the issues of tourism potentiality of Thung Fa Bot weekend market into the cultural tourism attraction in San Pa Tong District, Chiang Mai Province. A study was created containing Mixed Methodology Research. The data collection was focus group and in-depth interviews from the target population and questionnaires of stakeholders. The study was determined that context of socio-cultural and economic structure,which was relying on farming in the past. The potentiality level to be the cultural tourist attraction in overall was moderate.the aspect of tourist Attraction and Spirit of a community were in high level. On the other hand Accessibility, Activities and Participation civil organizations were in moderate level. There were only the Amenities and Ancillary Services had shown on low level. The results suggested the need to develop its potentiality of cultural tourist attraction in [1] Amenities and Ancillary Services management at the tourist spots and tourism promoting and [2] Linking network with government agencies, private sectors, and communities to join in tourism management in order to enlarge Thung Fha Bod Weekend Market becoming the greater cultural tourism attraction for the tourists.

  18. Dinuclear Tetrapyrazolyl Palladium Complexes Exhibiting Facile Tandem Transfer Hydrogenation/Suzuki Coupling Reaction of Fluoroarylketone

    KAUST Repository

    Dehury, Niranjan

    2016-07-18

    Herein, we report an unprecedented example of dinuclear pyrazolyl-based Pd complexes exhibiting facile tandem catalysis for fluoroarylketone: Tetrapyrazolyl di-palladium complexes with varying Pd-Pd distances efficiently catalyze the tandem reaction involving transfer hydrogenation of fluoroarylketone to the corresponding alcohol and Suzuki-Miyaura cross coupling reaction of the resulting fluoroarylalcohol under moderate reaction conditions, to biaryl alcohol. The complex with the shortest Pd-Pd distance exhibits the highest tandem activity among its di-metallic analogues, and exceeds in terms of activity and selectivity the analogous mononuclear compound. The kinetics of the reaction indicates clearly that reductive transformation of haloarylketone into haloaryalcohol is the rate determining step in the tandem reaction. Interestingly while fluoroarylketone undergoes the multistep tandem catalysis, the chloro- and bromo-arylketones undergo only a single step C-C coupling reaction resulting in biarylketone as the final product. Unlike the pyrazole based Pd compounds, the precursor PdCl2 and the phosphine based relevant complexes (PPh3)2PdCl2 and (PPh3)4Pd are found to be unable to exhibit the tandem catalysis.

  19. Practical, economical, and eco-friendly starch-supported palladium catalyst for Suzuki coupling reactions.

    Science.gov (United States)

    Baran, Talat

    2017-06-15

    In catalytic systems, the support materials need to be both eco friendly and low cost as well as having high thermal and chemical stability. In this paper, a novel starch supported palladium catalyst, which had these outstanding properties, was designed and its catalytic activity was evaluated in a Suzuki coupling reaction under microwave heating with solvent-free and mild reaction conditions. The starch supported catalyst gave remarkable reaction yields after only 5min as a result of the coupling reaction of the phenyl boronic acid with 23 different substrates, which are bearing aril bromide, iodide, and chloride. The longevity of the catalyst was also investigated, and the catalyst could be reused for 10 runs. The starch supported Pd(II) catalyst yielded remarkable TON (up to 25,000) and TOF (up to 312,500) values by using a simple, fast and eco-friendly method. In addition, the catalytic performance of the catalyst was tested against different commercial palladium catalysts, and the green starch supported catalyst had excellent selectivity. The catalytic tests showed that the novel starch based palladium catalyst proved to be an economical and practical catalyst for the synthesis of biaryl compounds. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Palladium Loaded on Magnetic Nanoparticles as Efficient and Recyclable Catalyst for the Suzuki- Miyaura Reaction

    Directory of Open Access Journals (Sweden)

    H. Khojasteh

    2015-07-01

    Full Text Available Palladium is the best metal catalyst for Suzuki cross coupling reaction for synthesize of unsymmetrical biaryl compounds. But its high cost limits its application in wide scale. Using of nanoscale particles as active catalytic cites is a good approach for reducing needed noble metal. By loading precious nanoparticles on magnetic nanocores as a support, recycling and reusing of catalyst will be possible. Magnetic nanoparticles have super paramagnetic feature and applying an external magnetic field can collect the supported catalyst from reaction milieu simply. In this work new palladium catalyst immobilized on modified magnetic nanoparticles containing NNO donor atoms were synthesized. Then the catalyst characterized by FT-IR spectroscopy, thermogravimetric analysis, X-ray diffraction and ICP. Prepared catalyst showed high activity in the Suzuki– Miyaura cross-coupling reaction of phenylboronic acid with aryl halides. Activity, Pd loading, reusability and Pd leaching of catalyst were studied. Results showed that the supported catalyst has the advantage to be completely recoverable with the simple application of an external magnetic field.

  1. Morphological patterns of lip prints in Mangaloreans based on Suzuki and Tsuchihashi classification

    Science.gov (United States)

    Jeergal, Prabhakar A; Pandit, Siddharth; Desai, Dinkar; Surekha, R; Jeergal, Vasanti A

    2016-01-01

    Introduction: Cheiloscopy is the study of the furrows or grooves present on the red part or vermilion border of the human lips. The present study aims to classify the characteristics of lip prints and to know the most common morphological pattern specific to Mangalorean people of Southern India. For the first time, this study also assesses the association between gender and different lip segments within a population. Materials and Methods: A total of 200 residents of Mangalore (100 males and 100 females) were included of age ranging from 18 years to 60 years. Materials used to take the impression of lips included red lipstick, A4 size white bond paper and cellophane tape. The prints obtained were scanned using a Canon Image Scanner and stored in a folder on a personal computer. The images were cropped and inverted in gray scale using Adobe Photoshop software. Each lip print was divided into eight segments and was examined. Suzuki and Tsuchihashi's classification (1970) was used to classify the types of grooves, and the results were statistically analyzed. Six types of grooves were recorded in the Mangalorean's lips. Statistical Analysis: Association between gender and different lip segments was tested using Chi-square analysis in the given population. Results: In males, the groove Type I' was the highest recorded followed by Type III, Type II, Type I, Type IV and Type V in descending order. In females, Type I' was the highest recorded followed by Type II, Type III, Type IV, Type I and Type V in descending order. Conclusion: Males and females displayed statistically significant differences in lip print patterns for different lip sites: lower medial lip, as well as upper and lower lateral segments. Only the upper medial lip segment displayed no statistically significant difference in lip print pattern between males and females. This shows that the distribution of lip prints is generally dissimilar for males and females, with varying predominance according to lip

  2. Higher spin currents in the enhanced N=3 Kazama-Suzuki model

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Changhyun; Kim, Hyunsu [Department of Physics, Kyungpook National University,Taegu 41566 (Korea, Republic of)

    2016-12-01

    The N=3 Kazama-Suzuki model at the ‘critical’ level has been found by Creutzig, Hikida and Ronne. We construct the lowest higher spin currents of spins ((3/2),2,2,2,(5/2),(5/2),(5/2),3) in terms of various fermions. In order to obtain the operator product expansions (OPEs) between these higher spin currents, we describe three N=2 OPEs between the two N=2 higher spin currents denoted by ((3/2),2,2,(5/2)) and (2,(5/2),(5/2),3) (corresponding 36 OPEs in the component approach). Using the various Jacobi identities, the coefficient functions appearing on the right hand side of these N=2 OPEs are determined in terms of central charge completely. Then we describe them as one single N=3 OPE in the N=3 superspace. The right hand side of this N=3 OPE contains the SO(3)-singlet N=3 higher spin multiplet of spins (2,(5/2),(5/2),(5/2),3,3,3,(7/2)), the SO(3)-singlet N=3 higher spin multiplet of spins ((5/2),3,3,3,(7/2),(7/2),(7/2),4), and the SO(3)-triplet N=3 higher spin multiplets where each multiplet has the spins (3,(7/2),(7/2),(7/2),4,4,4,(9/2)), in addition to N=3 superconformal family of the identity operator. Finally, by factoring out the spin-(1/2) current of N=3 linear superconformal algebra generated by eight currents of spins ((1/2),1,1,1,(3/2),(3/2),(3/2),2), we obtain the extension of so-called SO(3) nonlinear Knizhnik Bershadsky algebra.

  3. A convergent approach to the total synthesis of telmisartan via a Suzuki cross-coupling reaction between two functionalized benzimidazoles.

    Science.gov (United States)

    Martin, Alex D; Siamaki, Ali R; Belecki, Katherine; Gupton, B Frank

    2015-02-06

    A direct and efficient total synthesis has been developed for telmisartan, a widely prescribed treatment for hypertension. This approach brings together two functionalized benzimidazoles using a high-yielding Suzuki reaction that can be catalyzed by either a homogeneous palladium source or graphene-supported palladium nanoparticles. The ability to perform the cross-coupling reaction was facilitated by the regio-controlled preparation of the 2-bromo-1-methylbenzimidazole precursor. This convergent approach provides telmisartan in an overall yield of 72% while circumventing many issues associated with previously reported processes.

  4. Aziridine- and Azetidine-Pd Catalytic Combinations. Synthesis and Evaluation of the Ligand Ring Size Impact on Suzuki-Miyaura Reaction Issues

    Directory of Open Access Journals (Sweden)

    Hamza Boufroura

    2017-01-01

    Full Text Available The synthesis of new vicinal diamines based on aziridine and azetidine cores as well as the comparison of their catalytic activities as ligand in the Suzuki-Miyaura coupling reaction are described in this communication. The synthesis of three- and four-membered ring heterocycles substituted by a methylamine pendant arm is detailed from the parent nitrile derivatives. Complexation to palladium under various conditions has been examined affording vicinal diamines or amine-imidate complexes. The efficiency of four new catalytic systems is compared in the preparation of variously substituted biaryls. Aziridine- and azetidine-based catalytic systems allowed Suzuki-Miyaura reactions from aryl halides including chlorides with catalytic loadings until 0.001% at temperatures ranging from 100 °C to r.t. The evolution of the Pd-metallacycle ring strain moving from azetidine to aziridine in combination with a methylamine or an imidate pendant arm impacted the Suzuki-Miyaura reaction issue.

  5. N-BUTYL SUBSTITUTED N-HETEROCYCLIC CARBENE-PD(II-PYRIDINE (PEPPSI COMPLEXES: SYNTHESIS, CHARACTERIZATION AND CATALYTIC ACTIVITY IN THE SUZUKI-MIYAURA REACTION

    Directory of Open Access Journals (Sweden)

    Rukiye Fırıncı

    2016-08-01

    Full Text Available A series of N-butyl substituted imidazolium salts, (1a-c and their pyridine enhanced precatalyst preparation stabilization and initiation (PEPPSI themed palladium N-heterocyclic carbene complexes (2a-c were synthesized and characterized. Pd-NHC complexes were fully determined by elemental analysis and spectroscopic. The synthesized complexes were tested in Suzuki-Miyaura cross-coupling reaction. These complexes were found to be efficient catalysts for the Suzuki-Miyaura reaction of phenylboronic acid with aryl bromides.

  6. Miswak mediated green synthesized palladium nanoparticles as effective catalysts for the Suzuki coupling reactions in aqueous media

    Directory of Open Access Journals (Sweden)

    Mujeeb Khan

    2017-05-01

    Full Text Available Green and eco-friendly synthesis of palladium nanoparticles NPs is carried out under facile and eco-friendly conditions using an aqueous solution of Salvadora persica L. (SP root extract (RE as a bioreductant, which is commonly known as Miswak. The as-synthesized Pd NPs were characterized using various spectroscopic and microscopic techniques, including, UV–Vis spectroscopy, FT-IR spectroscopy, XRD, ICP-MS and TEM. Detailed investigations of the Pd NPs have confirmed that the polyphenolic phytomolecules present in the RE of Miswak not only act as a bioreductant by facilitating the reduction and growth of Pd NPs, but they also functionalize the surface of Pd NPs and stabilized them in various solvents. Furthermore, the catalytic activity of the green synthesized Pd NPs was also tested toward the Suzuki coupling reactions of various aryl halides in aqueous media. The as-prepared Pd NPs exhibited superior catalytic activity and reusability for the Suzuki coupling reaction in aqueous and aerobic conditions. The kinetics of the reaction studied by GC revealed that the conversion of various aryl halides to biphenyl takes place in a short time.

  7. Insights into the catalytic activity of [Pd(NHC)(cin)Cl] (NHC = IPr, IPrCl, IPrBr) complexes in the Suzuki-Miyaura reaction

    KAUST Repository

    Nolan, Steven Patrick; Izquierdo, Frederic; Zinser, Caroline; Minenkov, Yury; Cordes, David; Slawin, Alexandra; Cavallo, Luigi; Nahra, Fady; Cazin, Catherine

    2017-01-01

    The influence of C4,5-halogenation on palladium N-heterocyclic carbene complexes and their activity in the Suzuki-Miyaura reaction have been investigated. Two [Pd(NHC)(cin)Cl] complexes bearing IPrCl and IPrBr ligands were synthesized. After

  8. Ligand-Free Suzuki-Miyaura Coupling Reactions Using an Inexpensive Aqueous Palladium Source: A Synthetic and Computational Exercise for the Undergraduate Organic Chemistry Laboratory

    Science.gov (United States)

    Hill, Nicholas J.; Bowman, Matthew D.; Esselman, Brian J.; Byron, Stephen D.; Kreitinger, Jordan; Leadbeater, Nicholas E.

    2014-01-01

    An inexpensive procedure for introducing the Suzuki-Miyaura coupling reaction into a high-enrollment undergraduate organic chemistry laboratory course is described. The procedure employs an aqueous palladium solution as the catalyst and a range of para-substituted aryl bromides and arylboronic acids as substrates. The coupling reactions proceed…

  9. Observation of Binuclear Palladium Clusters Upon ESI-MS Monitoring of the Suzuki-Miyaura Cross-Coupling Catalyzed by a Dichloro-bis(aminophosphine) Complex of Palladium

    Czech Academy of Sciences Publication Activity Database

    Agrawal, Divya; Schröder, Detlef; Frech, C. M.

    2011-01-01

    Roč. 30, č. 13 (2011), s. 3579-3587 ISSN 0276-7333 Institutional research plan: CEZ:AV0Z40550506 Keywords : catalysis * C-C coupling * electrospray ionization * palladium * Suzuki-Miyaura coupling Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.963, year: 2011

  10. Concise synthesis of the hasubanan alkaloid (±)-cepharatine A using a Suzuki coupling reaction to effect o,p-phenolic coupling.

    Science.gov (United States)

    Magnus, Philip; Seipp, Charles

    2013-09-20

    Suzuki coupling of 10 and 11 resulted in 9, which was O-alkylated to provide 12. Treatment of 12 with CsF in DMF resulted in the formation of the completed core structure 13 in a single step. Reductive amination of 13 completed the synthesis of (±)-cepharatine A, 4.

  11. Simple synthesis of P(Cbz-alt-TBT) and PCDTBT by combining direct arylation with suzuki polycondensation of heteroaryl chlorides.

    Science.gov (United States)

    Lombeck, Florian; Matsidik, Rukiya; Komber, Hartmut; Sommer, Michael

    2015-01-01

    Direct arylation (DA) of 2-chlorothiophene and 2-chloro-3-hexylthiophene with 4,7-dibromo-2,1,3-benzothiadiazole is used to synthesize 4,7-bis(5-chloro-2-thienyl)-2,1,3-benzothiadiazole (TBTCl2) and 4,7-bis(5-chloro-4-hexyl-2-thienyl)-2,1,3-benzothiadiazole (DH-TBTCl2) in one step. Suitable conditions of the Suzuki polycondensations (SPC) of TBTCl2 and DH-TBTCl2 with the carbazole comonomer CbzPBE2 are established, furnishing PCDTBT and P(Cbz-alt-TBT) with high molecular weight and yield. Compared with control samples made from the corresponding dibromides, high-temperature NMR and UV-vis spectroscopy indicate similar properties for PCDTBT but an increased content of Cbz-Cbz homocouplings for P(Cbz-alt-TBT). © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. QuadraPure-Supported Palladium Nanocatalysts for Microwave-Promoted Suzuki Cross-Coupling Reaction under Aerobic Condition

    Directory of Open Access Journals (Sweden)

    Kin Hong Liew

    2014-01-01

    Full Text Available Cross-linked resin-captured palladium (XL-QPPd was readily prepared by simple physical adsorption onto the high loading QuadraPure macroporous resin and a subsequent reduction process. To enhance the mechanical stability, entrapped palladium nanocatalysts were cross-linked with succinyl chloride. Both transmission electron microscopy images and X-ray diffraction analysis revealed that the palladium nanoparticles were well dispersed with diameters ranging in 4–10 nm. The catalyst performed good catalytic activity in microwave-promoted Suzuki cross-coupling reactions in water under aerobic condition with mild condition by using various aryl halides and phenylboronic acid. In addition, the catalyst showed an excellent recyclability without significant loss of catalytic activity.

  13. Preventive Effect of Pine Bark Extract (Flavangenol on Metabolic Disease in Western Diet-Loaded Tsumura Suzuki Obese Diabetes Mice

    Directory of Open Access Journals (Sweden)

    Tsutomu Shimada

    2011-01-01

    Full Text Available It is known that the metabolic syndrome has a multi-factorial basis involving both genetic and environmental risk factors. In this study, Tsumura Suzuki Obese Diabetes (TSOD mice, a mouse model of multi-factorial, hereditary, obese type II diabetes, were given a Western diet (WTD as an environmental factor to prepare a disease model (TSOD-WTD and to investigate the preventive effects of Pine bark extract (Flavangenol against obesity and various features of metabolic disease appearing in this animal model. In contrast to control Tsumura Suzuki Non-obesity (TSNO mice, TSOD mice were obese and suffered from other metabolic complications. WTD-fed TSOD mice developed additional features such as hyperinsulinemia, abnormal glucose/lipid metabolism and fatty liver. The treatment with Flavangenol had a suppressive effect on increase in body weight and accumulation of visceral and subcutaneous fat, and also showed preventive effects on symptoms related to insulin resistance, abnormal glucose/lipid metabolism and hypertension. Flavangenol also increased the plasma concentration of adiponectin and decreased the plasma concentration of TNF-α. We next investigated the effect of Flavangenol on absorption of meal-derived lipids. Flavangenol suppressed absorption of neutral fat in an olive-oil-loading test (in vivo and showed an inhibitory effect on pancreatic lipase (in vitro. The above results suggest that Flavangenol has a preventive effect on severe metabolic disease due to multiple causes that involve both genetic and environmental risk factors. The mechanism of action might involve a partial suppressive effect of meal-derived lipids on absorption.

  14. [Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

    Index Scriptorium Estoniae

    Künnap, Ago, 1941-

    2010-01-01

    Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

  15. Effectiveness of Traditional Chinese Medicine Compound JieDuTongLuoShengJin Granules Treatment in Primary Sjögren’s Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    Directory of Open Access Journals (Sweden)

    Ben Li

    2017-01-01

    Full Text Available Objective. To evaluate the clinical therapeutic efficacy and safety of JieDuTongLuoShengJin granules + HCQ in patients with pSS. Methods. 40 patients with low-activity-level pSS and without visceral involvement participated in this study and were randomized to receive either JieDuTongLuoShengJin granules with HCQ or placebo with HCQ. Patients and investigators were blinded to treatment allocation. The primary endpoint was week 12 ESSPRI score, while secondary endpoints included ESSDAI, salivary and lacrimal gland function, and some laboratory variables. Safety-related data were also assessed. Results. Comparing with the placebo group, the treatment group experienced statistically significant improvement in the mean change from baseline for the primary endpoint of ESSPRI score and also in PGA. Moreover, in comparison with baseline values, the treatment group had significantly improved ESSDAI score, unstimulated saliva flow rate, and several laboratory variables. However, upon comparison of the two groups, there were no significant differences for them. The incidence of AEs was 10.0%, one in treatment group and three in placebo group. Conclusion. Treatment with a combination of JieDuTongLuoShengJin granules with HCQ is effective in improving patients’ subjective symptoms and some objective indicators of pSS. These results indicate that JieDuTongLuoShengJin is promising as a safe and effective treatment of pSS.

  16. Building New Education Model to Enhance the Comprehensive Competence of the Medical Students The exploration of PRICE Education Model in School of Medicine, Shanghai Jiao Tong University

    Institute of Scientific and Technical Information of China (English)

    Gang Huang; Bingjie Lu; Jifeng Fu; Yanping Zhang; Wenhan Mei; Yan Li; Yifei Wang

    2014-01-01

    To enhance the competence of medical students, Shanghai Jiao Tong University School of Medicine innovates the new PRICE education model, through Problem-based Learning(P) and Research-based learning(R), guides the students to give full play to the active learning; break the traditional discipline-centered teaching model by an integrated curriculum(I),combines with clinical practice-based learning(C) to solve the disjointed question between the basic theory and clinical practice in medical education, uses the comprehensive evaluation system(E) to assess the learning effect of the students and the quality of the teaching. The PRICE education model is verified by our educational practice.

  17. New geranylated flavanones from the fruits of Paulownia catalpifolia Gong Tong with their anti-proliferative activity on lung cancer cells A549.

    Science.gov (United States)

    Gao, Tian-yang; Jin, Xing; Tang, Wen-zhao; Wang, Xiao-jing; Zhao, Yun-xue

    2015-09-01

    Three new geranylated flavanones, named as paucatalinone A (1), B (2), and isopaucatalinone B (3), were isolated from the fruits of Paulownia catalpifolia Gong Tong (Scrophulariaceae). Their structures were well determined by means of IR, MS, 1D and 2D NMR, and CD techniques. Paucatalinone A (1) is the first sample as a dimeric geranylated flavanone derivative isolated from natural products. Paucatalinone A (1) displayed good antiproliferative effects on human lung cancer cells A549 and resulted in a clear increase of the percentage of cells in G1 phase and a decrease in the percentage of cells in S and G2/M phases in comparison with control cells. Copyright © 2015. Published by Elsevier Ltd.

  18. Insights into the catalytic activity of [Pd(NHC)(cin)Cl] (NHC = IPr, IPrCl, IPrBr) complexes in the Suzuki-Miyaura reaction

    KAUST Repository

    Nolan, Steven Patrick

    2017-09-06

    The influence of C4,5-halogenation on palladium N-heterocyclic carbene complexes and their activity in the Suzuki-Miyaura reaction have been investigated. Two [Pd(NHC)(cin)Cl] complexes bearing IPrCl and IPrBr ligands were synthesized. After determining electronic and steric properties of these ligands, their properties were compared to those of [Pd(IPr)(cin)Cl]. The three palladium complexes were studied using DFT calculations to delineate their behaviour in the activation step leading to the putative 12-electron active catalyst. Experimentally, their catalytic activity in the Suzuki-Miyaura reaction involving a wide range of coupling partners (30 entries) at low catalyst loading was studied.

  19. FAKTOR PSIKOLOGIS, LINGKUNGAN DAN BAURAN PEMASARAN YANG MEMPENGARUHI PEMBELIAN SEPEDA MOTOR Studi Pada Konsumen Sepeda Motor Bebek 4-tak Merk Suzuki dan Honda di Kota Banjarmasin

    Directory of Open Access Journals (Sweden)

    Taufiq Adi Rahmanie

    2012-05-01

    Full Text Available ABSTRAK Penelitian ini dilakukan untuk mengetahui faktor psikologis, lingkungan dan bauran pemasaran yang mempengaruhi pembelian sepeda motor bebek 4-tak merk Suzuki dan Honda di Kota Banjarmasin, dan untuk mengetahui variabel yang dominan terhadap keputusan pembelian. Penelitian ini dilakukan di Kota Banjarmasin. Pengambilan sampel dilakukan dengan teknik non random sampling dengan motode convenience sampling, dengan jumlah sampel 706 responden (355 konsumen Suzuki dan  351 konsumen Honda. Tingkat signifikansi yang ditetapkan dalam penelitian ini adalah 5%. Sebanyak 49 item dalam daftar pertanyaan yang diuraikan dalam 12 variabel dalam faktor psikologis, lingkungan dan bauran pemasaran. Pengujian terhadap semua instrumen penelitian menunjukkan tingkat reliabilitas dan validitas yang tinggi. Hasil penelitian ini semua variabel bebas yaitu persepsi (X1, sikap (X2, gaya hidup (X3, kepribadian (X4, budaya (X5, kelas sosial (X6, kelompok referensi (X7, situasi penentu (X8, produk (X9, harga (X10, promosi (X11 dan distribusi (X12 mempunyai korelasi yang signifikan terhadap keputusan pembelian sepeda motor bebek 4-tak merk Suzuki dan Honda. Diantara keduabelas variabel tersebut, variabel persepsi (X1, sikap (X2, gaya hidup (X3, kelompok referensi (X7, situasi penentu (X8 dan produk (X9 berpengaruh secara nyata terhadap keputusan pembelian sepeda motor bebek 4-tak merk Suzuki dan Honda di Kota Banjarmasin. Koefisien determinasi (R2 sebesar 0.591 menunjukkan kontribusi variabel-variabel independen untuk menjelaskan variabel dependen sebesar 59.1%. Sedangkan variabel yang paling dominan pengaruhnya adalah sikap sebesar 39.6%.   Kata kunci: pemasaran, bauran, psikologis ABSTRACT This research has been done to know psychological, environmental, marketing mix to influence 4 stroke bebek motorcycle (Honda and Suzuki buying in Banjarmasin, and also to know the dominant variable on buying decision. This research has been done in Banjarmasin. Writer uses non

  20. Pd-catalyzed Suzuki-Miyaura coupling reaction in the synthesis of 5-aryl-1-[2-(phosphonomethoxy)ethyl]uracils as potential multisubstrate inhibitors of thymidine phosphorylase

    Czech Academy of Sciences Publication Activity Database

    Pomeisl, Karel; Holý, Antonín; Pohl, Radek

    2007-01-01

    Roč. 48, č. 17 (2007), s. 3065-3067 ISSN 0040-4039 R&D Projects: GA MŠk 1M0508 Grant - others:Descartes Prize(XE) HPAW-CT-2002-9001 Institutional research plan: CEZ:AV0Z40550506 Keywords : acyclic nucleoside phosphonates * thymidine phosphorylase * Suzuki coupling * pyrimidine Subject RIV: CC - Organic Chemistry Impact factor: 2.615, year: 2007

  1. Reusable Polymer-Supported Terpyridine Palladium Complex for Suzuki-Miyaura, Mizoroki-Heck, Sonogashira, and Tsuji-Trost Reaction in Water

    Directory of Open Access Journals (Sweden)

    Takuya Nagamine

    2011-03-01

    Full Text Available A novel heterogeneous transition-metal catalyst comprising a polymer-supported terpyridine palladium(II complex was prepared and found to promote the Suzuki-Miyaura, Mizoroki-Heck, Sonogashira, and Tsuji-Trost, reactions in water under aerobic conditions with a high to excellent yield. The catalyst was recovered by simple filtration and directly reused several times without loss of catalytic activity.

  2. Multi-scale modelling of Suzuki segregation in γ′ precipitates in Ni and Co-base superalloys

    Directory of Open Access Journals (Sweden)

    Srimannarayana P.

    2014-01-01

    Full Text Available The high temperature strength of alloys with (γ + γ′ microstructure is primarily due to the resistance of the ordered precipitate to cutting by matrix dislocations. Such shearing requires higher stresses since it involves the creation of a planar fault. Planar fault energy is known to be dependent on composition. This implies that the composition on the fault may be different from that in the bulk for energetic reasons. Such segregation (or desegregation of specific alloying elements to the fault may result in Suzuki strengthening which has not been explored extensively in these systems. In this work, segregation (or desegregation of alloying elements to planar faults was studied computationally in Ni3(Al,Ti and Co3(W,Al type γ′ precipitates. The composition dependence of APB energy and heat of mixing were evaluated from first principle electronic structure calculations. A phase field model incorporating the first principles results, was used to simulate the motion of an extended superdislocation under stress concurrently with composition evolution. Results reveal that in both systems, significant (desegregation occurs on equilibration. On application of stress, solutes were dragged along with the APB in some cases. Additionally, it was also noted the velocity of the superdislocation under an applied stress is strongly dependent on atomic mobility (i.e. diffusivity.

  3. Neuroprotective effects and UPLC-Q-TOF/MS-based active components identification of external applied a novel Wen-Luo-Tong microemulsion.

    Science.gov (United States)

    Lin, Hong-Mei; Lin, Long-Fei; Xia, Zhen-Zhen; Mao, Yong; Liu, Jia; Xu, Ling-Yan; Wu, Qing

    2017-11-13

    Chemotherapy induced neuropathy causes excruciating pain to cancer patients. Wen-Luo-Tong (WLT), a traditional Chinese medicinal compound, has been used to alleviate anti-cancer drug such as oxaliplatin-induced neuropathic pain for many years. However, the current route of administration of WLT is inconvenient and the active ingredients and mechanism of action of WLT are still unclear. To address these issues, we developed a novel formulation of WLT (W/O microemulsion) for the ease of application. New ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) methods were employed for analysis of the ingredients. We identified seven ingredients that penetrated through the skin into the Franz cell receptor solution and four of those ingredients were retained in skin tissue when WLT microemulsion was applied. We tested the microemulsion formulation on an oxaliplatin-induced neuropathy rat model and showed that this formulation significantly decreased oxaliplatin-induced mechanical hyperalgesia responses. Schwann cells (SCs) viability experiment in vitro was studied to test the protective effect of the identified seven ingredients. The result showed that Hydroxysafflor Yellow A, icariin, epimedin B and 4-dihydroxybenzoic acid significantly increased the viability of SCs after injured by Oxaliplatin. Our report presents the first novel formulation of WLT with neuroprotective effect and ease of use, which has potential for clinical applications.

  4. The taxonomic implication of frontal tubercles in Polypedilum subgenera diagnoses, with re-description of Polypedilum isigabeceum Sasa & Suzuki (Diptera, Chironomidae).

    Science.gov (United States)

    Yamamoto, Nao; Yamamoto, Masaru

    2016-11-15

    Polypedilum isigabeceum Sasa et Suzuki, 2000 was described as belonging to subgenus Polypedilum s. str. However, if we accept the conclusion of Sæther et al. (2010), the species might be placed into Kribionympha with P. unagiquartum Sasa, 1985 because of the presence of distinct frontal tubercles in the adult males. However, other taxonomic characters do not support their treatment. P. isigabeceum is re-described and reconfirmed to be assigned to the subgenus Polypedilum s. str. The taxonomic meaning of frontal tubercles is discussed for defining the subgeneric rankings within genus Polypedilum.

  5. Studies on Pd/NiFe2O4 catalyzed ligand-free Suzuki reaction in aqueous phase: synthesis of biaryls, terphenyls and polyaryls

    Directory of Open Access Journals (Sweden)

    Suresh B. Waghmode

    2011-03-01

    Full Text Available Palladium supported on nickel ferrite (Pd/NiF2O4 was found to be a highly active catalyst for the Suzuki coupling reaction between various aryl halides and arylboronic acids. The reaction gave excellent yields (70–98% under ligand free conditions in a 1:1 DMF/H2O solvent mixture, in short reaction times (10–60 min. The catalyst could be recovered easily by applying an external magnetic field. The polyaryls were similarly synthesized.

  6. Directed ortho metalation-based methodology. Halo-, nitroso-, and boro-induced ipso-desilylation. Link to an in situ Suzuki reaction.

    Science.gov (United States)

    Zhao, Zhongdong; Snieckus, Victor

    2005-06-23

    [reaction: see text] Treatment of DoM-derived silylated aromatics 2-4 under standard electrophilic halogenation conditions cleanly affords ipso-desilyation products 5-7, while nitration of methoxy-substituted analogues 8, 9 leads to non-ipso isomers 10, 12 and 11, 13, controlled by a silicon steric effect. Sequential ipso-borodesilylation of 2a, 3a, and 20 followed by treatment with aryl halides under Pd-catalyzed conditions constitutes an in situ Suzuki-Miyaura cross-coupling protocol to biaryls and heterobiaryls 23.

  7. [PdA (IPr*) (cinnamyl)Cl]: An efficient pre-catalyst for the preparation of tetra-ortho-substituted biaryls by Suzuki-Miyaura cross-coupling

    KAUST Repository

    Chartoire, Anthony

    2012-03-13

    The bigger the better: The new well-defined [Pd(IPr*)(cin)Cl] pre-catalyst is described (see scheme). This complex proves to be highly active in the Suzuki-Miyaura cross-coupling for the synthesis of tetra-ortho- substituted biaryls under mild conditions. IPr* is reported as the largest N-heterocyclic carbene (NHC) to date for [Pd(NHC)(cin)Cl] complexes, explaining the high reactivity observed for this complex in this challenging transformation. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Pd-isatin Schiff base complex immobilized onγ-Fe2O3 as a magnetically recyclable catalyst for the Heck and Suzuki cross-coupling reactions

    Institute of Scientific and Technical Information of China (English)

    Sara Sobhani; Farzaneh Zarifi

    2015-01-01

    A Pd‐isatin Schiff base complex immobilized onγ‐Fe2O3 (Pd‐isatin Schiff base‐γ‐Fe2O3) was synthe‐sized and characterized by Fourier transform infrared, scanning electron microscopy, high resolu‐tion transmission electron microscopy, X‐ray diffraction, thermogravimetric gravimetric analysis, inductively‐coupled plasma, X‐ray photoelectron spectroscopy, and elemental analysis. It was used as a magnetically reusable Pd catalyst for the Heck and Suzuki cross‐coupling reactions.

  9. [PdA (IPr*) (cinnamyl)Cl]: An efficient pre-catalyst for the preparation of tetra-ortho-substituted biaryls by Suzuki-Miyaura cross-coupling

    KAUST Repository

    Chartoire, Anthony; Lesieur, Mathieu; Falivene, Laura; Slawin, Alexandra M. Z.; Cavallo, Luigi; Cazin, Catherine S J; Nolan, Steven P.

    2012-01-01

    The bigger the better: The new well-defined [Pd(IPr*)(cin)Cl] pre-catalyst is described (see scheme). This complex proves to be highly active in the Suzuki-Miyaura cross-coupling for the synthesis of tetra-ortho- substituted biaryls under mild conditions. IPr* is reported as the largest N-heterocyclic carbene (NHC) to date for [Pd(NHC)(cin)Cl] complexes, explaining the high reactivity observed for this complex in this challenging transformation. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Up-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 Cells.

    Directory of Open Access Journals (Sweden)

    Hong Sun

    Full Text Available Cytochrome P450 2C19 (CYP2C19 is an important drug-metabolizing enzyme (DME, which is responsible for the biotransformation of several kinds of drugs such as proton pump inhibitors, platelet aggregation inhibitors and antidepressants. Previous studies showed that Buchang NaoXinTong capsules (NXT increased the CYP2C19 metabolic activity in vitro and enhanced the antiplatelet effect of clopidogrel in vivo. However, the underlying molecular mechanism remained unclear. In the present study, we examined whether Pregnane X receptor (PXR plays a role in NXT-mediated regulation of CYP2C19 expression.We applied luciferase assays, real-time quantitative PCR (qPCR, Western blotting and cell-based analysis of metabolic activity experiments to investigate the NXT regulatory effects on the CYP2C19 promoter activity, the mRNA/ protein expression and the metabolic activity.Our results demonstrated that NXT significantly increased the CYP2C19 promoter activity when co-transfected with PXR in HepG2 cells. Mutations in PXR responsive element abolished the NXT inductive effects on the CYP2C19 promoter transcription. Additionally, NXT incubation (150 and 250μg/mL also markedly up-regulated endogenous CYP2C19 mRNA and protein levels in PXR-transfected HepG2 cells. Correspondingly, NXT leaded to a significant enhancement of the CYP2C19 catalytic activity in PXR-transfected HepG2 cells.In summary, this is the first study to suggest that NXT could induce CYP2C19 expression via PXR activation.

  11. Visual-haptic integration with pliers and tongs: signal ‘weights’ take account of changes in haptic sensitivity caused by different tools

    Directory of Open Access Journals (Sweden)

    Chie eTakahashi

    2014-02-01

    Full Text Available When we hold an object while looking at it, estimates from visual and haptic cues to size are combined in a statistically optimal fashion, whereby the ‘weight’ given to each signal reflects their relative reliabilities. This allows object properties to be estimated more precisely than would otherwise be possible. Tools such as pliers and tongs systematically perturb the mapping between object size and the hand opening. This could complicate visual-haptic integration because it may alter the reliability of the haptic signal, thereby disrupting the determination of appropriate signal weights. To investigate this we first measured the reliability of haptic size estimates made with virtual pliers-like tools (created using a stereoscopic display and force-feedback robots with different ‘gains’ between hand opening and object size. Haptic reliability in tool use was straightforwardly determined by a combination of sensitivity to changes in hand opening and the effects of tool geometry. The precise pattern of sensitivity to hand opening, which violated Weber’s law, meant that haptic reliability changed with tool gain. We then examined whether the visuo-motor system accounts for these reliability changes. We measured the weight given to visual and haptic stimuli when both were available, again with different tool gains, by measuring the perceived size of stimuli in which visual and haptic sizes were varied independently. The weight given to each sensory cue changed with tool gain in a manner that closely resembled the predictions of optimal sensory integration. The results are consistent with the idea that different tool geometries are modelled by the brain, allowing it to calculate not only the distal properties of objects felt with tools, but also the certainty with which those properties are known. These findings highlight the flexibility of human sensory integration and tool-use, and potentially provide an approach for optimising the

  12. Pd-bound functionalized mesoporous silica as active catalyst for Suzuki coupling reaction: Effect of OAcˉ, PPh3 and Clˉ ligands on catalytic activity

    Science.gov (United States)

    Das, Trisha; Uyama, Hiroshi; Nandi, Mahasweta

    2018-04-01

    Three new palladium catalysts, PdCat-I, PdCat-II and PdCat-III, immobilized over heterogeneous silica support have been synthesized using different ligands attached to the palladium precursor. The ligands that have been used in this study are acetate, triphenylphosphine and chloride in PdCat-I, PdCat-II and PdCat-III, respectively. The ligands have different effect on stability of the compounds and impart different oxidation states to the metal center. The materials have been characterized by powder X-ray diffraction, nitrogen adsorption-desorption studies, transmission electron microscopy, thermal analysis, and different spectroscopic techniques. The Pd-content of the samples have been determined by ICP-AES analysis. The materials have been used as catalysts for Suzuki coupling reaction of aryl halides with phenylboronic acid under mild conditions. A comparative study has been carried out to ascertain the effect of the nature of different ligands on the outcome of the catalytic reactions. Products have been identified and estimated by 1H NMR and gas chromatography. The results show that the best yields are obtained with the catalyst containing triphenylphosphine as the ligand in methanol. Such type of work to study the effect of ligand on Suzuki coupling reaction over functionalized mesoporous silica heterogeneous catalysts have not been carried out so far.

  13. and Suzuki coupling reactions

    Indian Academy of Sciences (India)

    e-mail: aksingh@chemistry.iitd.ac.in. Abstract. ... chalcogen. These results are presented in this paper. 2. Experimental ... All the sol- vents were dried and distilled before use by well-known ... The precipitate was filtered, washed with cold ...

  14. Protective effects of traditional Chinese medicine formula NaoShuanTong capsule on haemorheology and cerebral energy metabolism disorders in rats with blood stasis.

    Science.gov (United States)

    Liu, Hong; Peng, Yao-Yao; Liang, Feng-Yin; Chen, Si; Li, Pei-Bo; Peng, Wei; Liu, Zhong-Zheng; Xie, Cheng-Shi; Long, Chao-Feng; Su, Wei-Wei

    2014-01-02

    NaoShuanTong capsule (NSTC), an oral traditional Chinese medicine formula, is composed of Pollen Typhae , Radix Paeoniae Rubra , Rhizoma Gastrodiae , Radix Rhapontici and Radix Curcumae . It has been widely used to treat ischemic stroke in clinic for many years in China. In addition to neuronal apoptosis, haemorheology and cerebral energy metabolism disorders also play an important role in the pathogenesis and development of ischemic stroke. The present study was designed to evaluate the in vivo protective effects of NSTC on haemorheology and cerebral energy metabolism disorders in rats with blood stasis. Sixty specific pathogen-free sprague-dawley rats, male only, were randomly divided into six groups (control group, model group, aspirin (100 mg/kg/d) group, NSTC low-dose (400 mg/kg/d) group, NSTC intermediate-dose (800 mg/kg/d) group, NSTC high-dose (1600 mg/kg/d) group) with 10 animals in each. The rats except those in the control group were placed in ice-cold water (0-4 °C) for 5 min during the time interval (4 h) of two adrenaline hydrochloride injections (0.8 mg/kg) to induce blood stasis. After treatment, whole blood viscosity at three shear rates, plasma viscosity and erythrocyte sedimentation rate significantly decreased in NSTC intermediate- and high-dose groups; erythrocyte aggregation index and red corpuscle electrophoresis index significantly decreased in all the three dose NSTC groups. Moreover, treatment with high-dose NSTC could significantly improve Na + -K + adenosine triphosphatase (ATPase) and Ca 2+ ATPase activity, as well as lower lactic acid level in brain tissues. These results demonstrated the protective effects of NSTC on haemorheology and cerebral energy metabolism disorders, which may provide scientific information for the further understanding of mechanism(s) of NSTC as a clinical treatment for ischemic stroke. Furthermore, the protective effects of activating blood circulation as observed in this study might create valuable

  15. Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki-Miyaura Cross-Coupling Reactions

    Czech Academy of Sciences Publication Activity Database

    Sabat, Nazarii; Nauš, Petr; Matyašovský, Ján; Dziuba, Dmytro; Poštová Slavětínská, Lenka; Hocek, Michal

    2016-01-01

    Roč. 48, č. 7 (2016), s. 1029-1045 ISSN 0039-7881 R&D Projects: GA ČR GAP207/11/0344 Institutional support: RVO:61388963 Keywords : nucleobases * deazapurines * pyrrolo[2,3-d]pyrimidines * Suzuki cross - coupling * arylation Subject RIV: CC - Organic Chemistry Impact factor: 2.650, year: 2016

  16. Plant Extract Mediated Eco-Friendly Synthesis of Pd@Graphene Nanocatalyst: An Efficient and Reusable Catalyst for the Suzuki-Miyaura Coupling

    Directory of Open Access Journals (Sweden)

    Mujeeb Khan

    2017-01-01

    Full Text Available Suzuki-Miyaura coupling reaction catalyzed by the palladium (Pd-based nanomaterials is one of the most versatile methods for the preparation of biaryls. However, use of organic solvents as reaction medium causes a big threat to environment due to the generation of toxic byproducts as waste during the work up of these reactions. Therefore, the use of water as reaction media has attracted tremendous attention due to its environmental, economic, and safety benefits. In this study, we report on the synthesis of green Pd@graphene nanocatalyst based on an in situ functionalization approach which exhibited excellent catalytic activity towards the Suzuki–Miyaura cross-coupling reactions of phenyl halides with phenyl boronic acids under facile conditions in water. The green and environmentally friendly synthesis of Pd@graphene nanocatalyst (PG-HRG-Pd is carried out by simultaneous reduction of graphene oxide (GRO and PdCl2 using Pulicaria glutinosa extract (PGE as reducing and stabilizing agent. The phytomolecules present in the plant extract (PE not only facilitated the reduction of PdCl2, but also helped to stabilize the surface of PG-HRG-Pd nanocatalyst, which significantly enhanced the dispersibility of nanocatalyst in water. The identification of PG-HRG-Pd was established by various spectroscopic and microscopic techniques, including, high-resolution transmission electron microscopy (HRTEM, X-ray diffraction (XRD, ultraviolet–visible spectroscopy (UV-Vis, Fourier transform infrared spectroscopy (FT-IR, and Raman spectroscopy. The as-prepared PG-HRG-Pd nanocatalyst demonstrated excellent catalytic activity towards the Suzuki-Miyaura cross coupling reactions under aqueous, ligand free, and aerobic conditions. Apart from this the reusability of the catalyst was also evaluated and the catalyst yielded excellent results upon reuse for several times with marginal loss of its catalytic performance. Therefore, the method developed for the green

  17. Ionic liquid and aqueous two-phase extraction based on salting-out coupled with high-performance liquid chromatography for the determination of seven rare ginsenosides in Xue-Sai-Tong injection.

    Science.gov (United States)

    Li, Lan-Jie; Jin, Yong-Ri; Wang, Xiao-Zhong; Liu, Ying; Wu, Qian; Shi, Xiao-Lei; Li, Xu-Wen

    2015-09-01

    A method of ionic liquid salt aqueous two-phase extraction coupled with high-performance liquid chromatography has been developed for the analysis of seven rare ginsenosides including Rg6 , F4 , 20(S)-Rg3 , 20(R)-Rg3 , Rk3 , Rk1 , and Rg5 in Xue-Sai-Tong injection. The injection was mixed with ionic liquid 1-butyl-3-methylimidazolium bromide aqueous solution, and a mixture was obtained. With the addition of sodium dodecyl sulfate and dipotassium phosphate into the mixture, the aqueous two-phase mixture was formed after ultrasonic treatment and centrifuged. Rare ginsenosides were extracted into the upper phase. To obtain a high extraction factors, various influences were considered systematically, such as the volume of ionic liquid, the category and amount of salts, the amount of sodium dodecyl sulfate, the pH value of system, and the time of ultrasonic treatment. Under the optimal condition, rare ginsenosides in Xue-Sai-Tong injection were enriched and detected, the recoveries of seven rare ginsenosides ranged from 90.05 to 112.55%, while relative standard deviations were lower than 2.50%. The developed method was reliable, rapid and sensitive for the determination of seven rare ginsenosides in the injections. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. [The affinity between Le family of Tong Ren Tang and acu-moxibustion as viewed from Mian xue tang zhen jiu ji cheng (Mian Xuetang's Synthetic Work of Acu-moxibustion)].

    Science.gov (United States)

    Huang, L X

    2017-11-28

    This compilation process of Mian xue tang zhen jiu ji cheng ( Mian Xuetang ' s Synthetic Work of Acu - moxibustion )was quite mysterious, the book's advent coincidentally met with several major historical events which made its value of decoding its historical functions far beyond its academic value. The editor of this book is Le Xianyang, the founder of Tong Ren Tang. While compiling this book, he also made a replica of Ming-Dynasty's Zhengtong bronze statue. More than 200 years later, Le Jingyu, the 12th generation of the Le family revised Ming Tang Tu inherited from his ancestors and engraved Ming Tang Tu on the stone for its standardization. This great achievement of Le family was no less than the recasting of the Tiansheng bronze statue and the reengraving Tong ren shu xue zhen jiu tu jing ( Illustrated Manual of Acupuncture Points of the Bronze Figure ) by support of state power for building the Beijing Imperial Hospital in the eighth year of the Zhengtong reign (1443).

  19. Simultaneous determination of phenolic acids and diterpenoids and their comparative pharmacokinetic study in normal and acute blood stasis rats by UFLC-MS/MS after oral administration of Guan-Xin-Shu-Tong capsules.

    Science.gov (United States)

    Gao, Xun; Mu, Jingqing; Guan, Shaoyi; Li, Qing; Du, Yiyang; Zhang, Huifen; Bi, Kaishun

    2018-01-01

    Guan-Xin-Shu-Tong capsules are one of the well-known and first-line Chinese traditional herbal formula for treating coronary heart disease. A validated and sensitive method via ultra fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) was established to simultaneously determinate five phenolic acids and four diterpenoids in rats in order to investigate their pharmacokinetic profiles firstly. Analytes were extracted by ethyl acetate and determined via multiple reaction monitoring mode in both positive and negative ion modes. The values for limit of quantification were in range of 0.025-1.250ng/ml. Inter- and intra-day precisions were no more than 10.9% with accuracy of -11.0%-10.6%, meanwhile the stable and suitable extraction recoveries were also obtained. And finally such excellent method was used to compare the pharmacokinetics of nine compounds in normal and acute blood stasis rats after oral administration of Guan-Xin-Shu-Tong capsules. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Direct observation of dislocation dissociation and Suzuki segregation in a Mg–Zn–Y alloy by aberration-corrected scanning transmission electron microscopy

    International Nuclear Information System (INIS)

    Yang Zhiqing; Chisholm, Matthew F.; Duscher, Gerd; Ma Xiuliang; Pennycook, Stephen J.

    2013-01-01

    Crystal defects in a plastically deformed Mg–Zn–Y alloy have been studied on the atomic scale using aberration-corrected scanning transmission electron microscopy, providing important structural data for understanding the material’s deformation behavior and strengthening mechanisms. Atomic scale structures of deformation stacking faults resulting from dissociation of different types of dislocations have been characterized experimentally, and modeled. Suzuki segregation of Zn and Y along stacking faults formed through dislocation dissociation during plastic deformation at 300 °C is confirmed experimentally on the atomic level. The stacking fault energy of the Mg–Zn–Y alloy is evaluated to be in the range of 4.0–10.3 mJ m −2 . The newly formed nanometer-wide stacking faults with their Zn/Y segregation in Mg grains play an important role in the superior strength of this alloy at elevated temperatures.

  1. Palladium Nanoparticles Immobilized on Poly(vinyl chloride-Supported Pyridinium as an Efficient and Recyclable Catalyst for Suzuki-Miyaura Cross-Coupling Reaction

    Directory of Open Access Journals (Sweden)

    Bo Zhou

    2011-01-01

    Full Text Available The palladium nanoparticles immobilized on the polymeric surface of poly(vinyl chloride-supported pyridinium (PVC-Py-Pd0 were achieved by a simple procedure by applying the corresponding functionalized polymer and palladium chloride in ethanol solution. The as-prepared catalyst (PVC-Py-Pd0 was found to be air and moisture stable and exhibits significant catalytic activity for Suzuki-Miyaura cross-coupling reaction of various aryl halides and phenylboronic acid under milder operating conditions. The procedure presented here showed several merits such as short reaction time, simple experimental and isolated procedure and excellent yields of products. Furthermore, the catalyst can be easily recovered and reused for at least six times with consistent activities.

  2. Synthesis and conformational analysis of new arylated-diphenylurea derivatives related to sorafenib drug via Suzuki-Miyaura cross-coupling reaction

    Science.gov (United States)

    Al-Masoudi, Najim A.; Essa, Ali Hashem; Alwaaly, Ahmed A. S.; Saeed, Bahjat A.; Langer, Peter

    2017-10-01

    Sorafenib, is a relatively new cytostatic drug approved for the treatment of renal cell and hepatocellular carcinoma. The development of new sorafenib analogues offers the possibility of generating structures of increased potency. To this end, a series of arylated-diphenylurea analogues 17-31 were synthesized via Suzuki-Miyaura coupling reaction, related to sorafenib by treatment of three diarylureas 2-4 having 3-bromo, 4-chloro and 2-iodo groups with various arylboronic acids. Conformational analysis of the new arylated urea analogues has been investigated using MOPAC 2016 of semi empirical PM7 Hamiltonian computational method. Our results showed that all compounds preferred the trans-trans conformations. Compound 17 has been selected to calculate the torsional energy profiles for rotation around the urea bonds and found to be existed predominantly in the trans-trans conformation with only very minimal fluctuation in conformation.

  3. Elucidation of the structure-property relationship of p-type organic semiconductors through rapid library construction via a one-pot, Suzuki-Miyaura coupling reaction.

    Science.gov (United States)

    Fuse, Shinichiro; Matsumura, Keisuke; Wakamiya, Atsushi; Masui, Hisashi; Tanaka, Hiroshi; Yoshikawa, Susumu; Takahashi, Takashi

    2014-09-08

    The elucidation of the structure-property relationship is an important issue in the development of organic electronics. Combinatorial synthesis and the evaluation of systematically modified compounds is a powerful tool in the work of elucidating structure-property relationships. In this manuscript, D-π-A structure, 32 p-type organic semiconductors were rapidly synthesized via a one-pot, Suzuki-Miyaura coupling with subsequent Knoevenagel condensation. Evaluation of the solubility and photovoltaic properties of the prepared compounds revealed that the measured solubility was strongly correlated with the solubility parameter (SP), as reported by Fedors. In addition, the SPs were correlated with the Jsc of thin-film organic solar cells prepared using synthesized compounds. Among the evaluated photovoltaic properties of the solar cells, Jsc and Voc had strong correlations with the photoconversion efficiency (PCE).

  4. Highly functionalized biaryls via Suzuki-Miyaura cross-coupling catalyzed by Pd@MOF under batch and continuous flow regimes.

    Science.gov (United States)

    Pascanu, Vlad; Hansen, Peter R; Bermejo Gómez, Antonio; Ayats, Carles; Platero-Prats, Ana E; Johansson, Magnus J; Pericàs, Miquel À; Martín-Matute, Belén

    2015-01-01

    A diverse set of more than 40 highly functionalized biaryls was synthesized successfully through the Suzuki-Miyaura cross-coupling reaction catalyzed by Pd nanoparticles supported in a functionalized mesoporous MOF (8 wt % Pd@MIL-101(Cr)-NH2 ). This could be achieved under some of the mildest conditions reported to date and a strong control over the leaching of metallic species could be maintained, despite the presence of diverse functional groups and/or several heteroatoms. Some of the targeted molecules are important intermediates in the synthesis of pharmaceuticals and we clearly exemplify the versatility of this catalytic system, which affords better yields than currently existing commercial procedures. Most importantly, Pd@MIL-101-NH2 was packed in a micro-flow reactor, which represents the first report of metallic nanoparticles supported on MOFs employed in flow chemistry for catalytic applications. A small library of 11 isolated compounds was created in a continuous experiment without replacing the catalyst, demonstrating the potential of the catalyst for large-scale applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Water-dispersable hybrid Au-Pd nanoparticles as catalysts in ethanol oxidation, aqueous phase Suzuki-Miyaura and Heck reactions

    KAUST Repository

    Song, Hyon Min

    2012-01-01

    The catalytic activities of water-dispersable Au@Pd core-shell nanoparticles (NPs) and Au-Pd alloy NPs were examined. There is growing interest in Au-Pd hybridized NPs in a supported matrix or non-supported forms as catalysts in various reactions that are not limited to conventional Pd-related reactions. Four different Au@Pd core-shell NPs in this study were prepared at room temperature with help from the emulsion phase surrounding the Au core NPs. Au-Pd alloy NPs were prepared over 90 °C, and underwent phase transfer to aqueous medium for their catalytic use. Au@Pd core-shell NPs show catalytic activity in ethanol oxidation reactions as electrocatalysts, and both core-shell and alloy NPs are good to excellent catalysts in various Suzuki-Miyaura and Heck reactions as heterogeneous catalysts. Specifically, Au@Pd core-shell NPs with sharp branched arms show the highest yield in the reactions tested in this study. A relatively small amount (0.25 mol%) was used throughout the catalytic reactions. © 2012 The Royal Society of Chemistry.

  6. Studies of the thermal dissolution process of the Suzuki phase of the Eu2+ ion in KBr single crystals by analysis of photoacoustic signals

    International Nuclear Information System (INIS)

    MejIa-Uriarte, E V; Castaneda-Guzman, R; Villagran-Muniz, M; Camarillo, E; A, J Hernandez; S, H Murrieta; Navarrete, M

    2003-01-01

    An experimental investigation of the thermal behaviour of the dissolution process of the Suzuki phase (SP) by continuous heating (1 deg. C min -1 ) of KBr:Eu 2+ crystals is reported in this work. The thermal profiles were determined by the correlation functions between subsequent photoacoustic (PA) signals registered during the dissolution process. The behaviour of the thermal profile is directly related to the absorption coefficient of the Eu 2+ ion in precipitated states that are present in the crystal. The PA signal is detected as a consequence of the non-radiative processes that take place after the excitation of the low-energy band of the Eu 2+ ion by means of a focused laser pulse at 355 nm. The results obtained by this method are compared with those simultaneously obtained by the photoluminescence (PL) technique. The samples were heated from room temperature to 205 deg. C. The PA signal and PL spectrum were obtained every 6 deg. C. The temperature range of the SP dissolution process was from 77 to 115 deg. C. These results are in agreement with those obtained by the PL technique and with the data reported in the literature

  7. Palladium-catalyzed Suzuki-Miyaura coupling of amides by carbon-nitrogen cleavage: general strategy for amide N-C bond activation.

    Science.gov (United States)

    Meng, Guangrong; Szostak, Michal

    2016-06-15

    The first palladium-catalyzed Suzuki-Miyaura cross-coupling of amides with boronic acids for the synthesis of ketones by sterically-controlled N-C bond activation is reported. The transformation is characterized by operational simplicity using bench-stable, commercial reagents and catalysts, and a broad substrate scope, including substrates with electron-donating and withdrawing groups on both coupling partners, steric-hindrance, heterocycles, halides, esters and ketones. The scope and limitations are presented in the synthesis of >60 functionalized ketones. Mechanistic studies provide insight into the catalytic cycle of the cross-coupling, including the first experimental evidence for Pd insertion into the amide N-C bond. The synthetic utility is showcased by a gram-scale cross-coupling and cross-coupling at room temperature. Most importantly, this process provides a blueprint for the development of a plethora of metal catalyzed reactions of typically inert amide bonds via acyl-metal intermediates. A unified strategy for amide bond activation to enable metal insertion into N-C amide bond is outlined ().

  8. Advantageous Microwave-Assisted Suzuki Polycondensation for the Synthesis of Aniline-Fluorene Alternate Copolymers as Molecular Model with Solvent Sensing Properties

    Directory of Open Access Journals (Sweden)

    Rebeca Vázquez-Guilló

    2018-02-01

    Full Text Available Polymerization via Suzuki coupling under microwave (µW irradiation has been studied for the synthesis of poly{1,4-(2/3-aminobenzene-alt-2,7-(9,9-dihexylfluorene} (PAF, chosen as molecular model. Briefly, µW-assisted procedures accelerated by two orders of magnitude the time required when using classical polymerization processes, and the production yield was increased (>95%. In contrast, although the sizes of the polymers that were obtained by non-conventional heating reactions were reproducible and adequate for most applications, with this methodology the molecular weight of final polymers were not increased with respect to conventional heating. Asymmetric orientation of the amine group within the monomer and the assignments of each dyad or regioregularity, whose values ranged from 38% to 95% with this molecule, were analysed using common NMR spectroscopic data. Additionally, the synthesis of a new cationic polyelectrolyte, poly{1,4-(2/3-aminobenzene-co-alt-2,7-[9,9´-bis(6’’-N,N,N-trimethylammonium-hexylfluorene]} dibromide (PAFAm, from poly{1,4-(2/3-aminobenzene-co-alt-2,7-[9,9´-bis(6’’-bromohexylfluorene]} (PAFBr by using previously optimized conditions for µW-assisted heating procedures was reported. Finally, the characterization of the final products from these batches showed unkown interesting solvatochromic properties of the PAF molecule. The study of the solvatochromism phenomena, which was investigated as a function of the polarity of the solvents, showed a well-defined Lippert correlation, indicating that the emission shift observed in PAF might be due to its interaction with surrounding environment. Proven high sensitivity to changes of its environment makes PAF a promising candidate of sensing applications.

  9. WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy.

    Science.gov (United States)

    Feng, Chengcheng; Xu, Lijuan; Guo, Shiyun; Chen, Qian; Shen, Yuguo; Zang, Deng; Ma, Li

    2018-01-01

    WenTong HuoXue Cream (WTHX-Cream) has been shown to effectively alleviate clinical symptoms of diabetic peripheral neuropathy (DPN). This study investigated the gene and protein expression of the pain-related molecule PLC- β 3 in the dorsal root ganglion (DRG) of DPN rats. 88 specific pathogen-free male Wistar rats were randomly divided into placebo (10 rats) and DPN model (78 rats) groups, and the 78 model rats were used to establish the DPN model by intraperitoneal injection of streptozotocin and were then fed a high-fat diet for 8 weeks. These rats were randomly divided into the model group, the high-, medium-, and low-dose WTHX-Cream + metformin groups, the metformin group, the capsaicin cream group, and the capsaicin cream + metformin group. After 4 weeks of continuous drug administration, the blood glucose, body weight, behavioral indexes, and sciatic nerve conduction velocity were measured. The pathological structure of the DRG and the sciatic nerve were observed. PLC- β 3 mRNA and protein levels in the DRG of rats were measured. Compared with the model group, the high-dose WTHX-Cream group showed increased sciatic nerve conduction velocity, improved sciatic nerve morphological changes, and increased expression of PLC- β 3 mRNA and protein in the DRG. This study showed that WTHX-Cream improves hyperalgesia symptoms of DPN by inhibiting the reduction of PLC- β 3 mRNA and protein expression in the diabetic DRG of DPN rats.

  10. Identification of C-geranylated flavonoids from Paulownia catalpifolia Gong Tong fruits by HPLC-DAD-ESI-MS/MS and their anti-aging effects on 2BS cells induced by H2O2.

    Science.gov (United States)

    Tang, Wen-Zhao; Wang, Ying-Ai; Gao, Tian-Yang; Wang, Xiao-Jing; Zhao, Yun-Xue

    2017-05-01

    The fruits of Paulownia catalpifolia Gong Tong are used as a Chinese folk herbal medicine for the treatment of enteritis, tonsillitis, bronchitis, and dysentery, etc. Our previous study has identified new C-geranylated flavanones with obvious anti-proliferative effects in lung cancer A549 cells. In the present study, a new C-geranylated flavone, paucatalinone C (1) and five known C-geranylated flavanones (2-6) were isolated. In addition, a total of 34 C-geranylated flavonoids were detected by HPLC-DAD-ESI-MS/MS coupling techniques from the CH 2 Cl 2 extract of P. catalpifolia. Futhermore, anti-aging effects of isolated compounds were evaluated in vitro with premature senescent 2BS cells induced by H 2 O 2 . Phytochemical results indicated that P. catalpifolia was a natural resource of abundant C-geranylated flavonoids. Diplacone (3) and paucatalinone A (5) were the potent anti-aging agents in the premature senescent 2BS cells induced by H 2 O 2 and the C-geranyl substituent may be an important factor because of its lipophilic character. Copyright © 2017 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

  11. WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy

    Directory of Open Access Journals (Sweden)

    Chengcheng Feng

    2018-01-01

    Full Text Available WenTong HuoXue Cream (WTHX-Cream has been shown to effectively alleviate clinical symptoms of diabetic peripheral neuropathy (DPN. This study investigated the gene and protein expression of the pain-related molecule PLC-β3 in the dorsal root ganglion (DRG of DPN rats. 88 specific pathogen-free male Wistar rats were randomly divided into placebo (10 rats and DPN model (78 rats groups, and the 78 model rats were used to establish the DPN model by intraperitoneal injection of streptozotocin and were then fed a high-fat diet for 8 weeks. These rats were randomly divided into the model group, the high-, medium-, and low-dose WTHX-Cream + metformin groups, the metformin group, the capsaicin cream group, and the capsaicin cream + metformin group. After 4 weeks of continuous drug administration, the blood glucose, body weight, behavioral indexes, and sciatic nerve conduction velocity were measured. The pathological structure of the DRG and the sciatic nerve were observed. PLC-β3 mRNA and protein levels in the DRG of rats were measured. Compared with the model group, the high-dose WTHX-Cream group showed increased sciatic nerve conduction velocity, improved sciatic nerve morphological changes, and increased expression of PLC-β3 mRNA and protein in the DRG. This study showed that WTHX-Cream improves hyperalgesia symptoms of DPN by inhibiting the reduction of PLC-β3 mRNA and protein expression in the diabetic DRG of DPN rats.

  12. Tongxinluo (Tong xin luo or Tong-xin-luo) capsule for unstable angina pectoris.

    Science.gov (United States)

    Wu, Taixiang; Harrison, R A; Chen, Xiaoyan; Ni, Juan; Zhou, Likun; Qiao, Jieqi; Wang, Qin; Wei, Jiafu; Xin, Duan; Zheng, Jie

    2006-10-18

    Tongxinluo capsule is a medicine consisting of traditional Chinese herbs and insects used for cardiovascular diseases in China and some other Asian countries. To date the evidence of its effect has not previously been subject to systematic review, making it difficult to derive robust conclusions about its actual benefits, and indeed, possible harms. To assess systematically the effects of tongxinluo capsule in people with unstable angina pectoris. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) on The Cochrane Library, Issue 4 2004, MEDLINE, EMBASE, Chinese Biomedical Database, China National Knowledge Infrastructure, Japana Centra Revuo Medicina (all 1995 to 2005). We also handsearched the relevant Chinese journals, checked with manufacturers and registers of ongoing studies. Randomised trials comparing either tongxinluo capsule only or standard treatment plus tongxinluo capsule with standard treatment or other anti-angina pectoris drugs, placebo or no intervention. Two authors identified relevant studies for the review independently and went on to abstract data, and assess trial quality. Authors of included studies were contacted to obtain further information as required. 18 short term follow-up trials involving 1413 people were included. The studies did not provide strong support of a benefit of tongxinluo for reducing the combined outcome of acute myocardial infarction, angioplasty (PTCA) coronary artery bypass graft (CABG) and sudden death or all-cause mortality (RR 0.42, 95% CI 0.07 to 2.59, P=0.35; RR 0.33, 95% CI 0.01to 7.78, P=0.49, respectively). Tongxinluo reduced the frequency of acute angina attacks (WMD -1.20, 95%CI -1.38 to -1.02, P<0.00001 and RR -2.36, 95%CI -2.53 to -2.18, P<0.00001, respectively), improved ECG (RR 1.31, 95% CI 1.08 to 1.57, P=0.005) and angina symptoms (RR 1.21, 95% CI 1.06 to 1.40; P=0.007). Tongxinluo in combination with routine angina therapy appears to reduce the risk of subsequent AMI, PTCA or CABG, angina attacks and severity, as well as improving symptoms and ischaemic changes on the electrocardiogram (ECG). Due to the methodological limitations of the studies, the evidence is insufficient to make any conclusive recommendations about the use of this treatment for patients presenting with unstable angina. Large high quality randomised controlled trials are warranted.

  13. Reference values and associated factors for Japanese newborns' blood pressure and pulse rate: the babies' and their parents' longitudinal observation in Suzuki Memorial Hospital on intrauterine period (BOSHI) study.

    Science.gov (United States)

    Satoh, Michihiro; Inoue, Ryusuke; Tada, Hideko; Hosaka, Miki; Metoki, Hirohito; Asayama, Kei; Murakami, Takahisa; Mano, Nariyasu; Ohkubo, Takayoshi; Yagihashi, Katsuyo; Hoshi, Kazuhiko; Suzuki, Masakuni; Imai, Yutaka

    2016-08-01

    Currently, normative means and ranges of blood pressure (BP) and pulse rates in Japanese newborns are not available. The objective of the present study was to estimate BP, pulse rate, and their distribution among Japanese newborns. Using oscillometric devices, arm or calf BP and pulse rate levels were obtained from 3148 infants born between 2007 and 2014, consecutively at Suzuki Memorial Hospital, Iwanuma, Japan. Of those, data from 2628 full-term, singleton newborns with BP measured on day 3 after birth were analyzed. Arm SBP/DBP and pulse rate in the reference group (n = 2628) were 70.5 ± 7.4/44.3 ± 6.7 mmHg and 117.3 ± 16.6 bpm, respectively. The 5-95th percentiles were 58-83 mmHg for SBP, 35-57 mmHg for DBP, and 91-145 bpm for pulse rate. Similar values were obtained from calf measurements. In multiple regression analysis, birth weight and spontaneous cephalic delivery were positively and light/deep sleep was inversely associated with higher arm SBP/DBP (P ≤ 0.04), whereas sex, Apgar score, gestational age, and mother's age did not significantly affect BP levels (P ≥ 0.06). Male sex, gestational age, spontaneous cephalic delivery, and light/deep sleep were inversely associated with higher pulse rate (P ≤ 0.02). The present study is the first to show the distributions of Asian newborns' BP levels and pulse rate. The assessment of newborns' BP levels and pulse rate should consider birth weight, gestational age after birth, and actual condition at BP measurement.

  14. Catalysis in the Service of Green Chemistry: Nobel Prize-Winning Palladium-Catalysed Cross-Couplings, Run in Water at Room Temperature: Heck, Suzuki-Miyaura and Negishi reactions carried out in the absence of organic solvents, enabled by micellar catalysis.

    Science.gov (United States)

    Lipshutz, Bruce H; Taft, Benjamin R; Abela, Alexander R; Ghorai, Subir; Krasovskiy, Arkady; Duplais, Christophe

    2012-04-01

    Palladium-catalysed cross-couplings, in particular Heck, Suzuki-Miyaura and Negishi reactions developed over three decades ago, are routinely carried out in organic solvents. However, alternative media are currently of considerable interest given an increasing emphasis on making organic processes 'greener'; for example, by minimising organic waste in the form of organic solvents. Water is the obvious leading candidate in this regard. Hence, this review focuses on the application of micellar catalysis, in which a 'designer' surfactant enables these award-winning coupling reactions to be run in water at room temperature.

  15. Effect of gamma irradiation on Hom Tong banana

    International Nuclear Information System (INIS)

    1971-01-01

    This report contains research on the use of gamma irradiation to retard the ripening and extend the shelf life of bananas. The major concerns were the effects that irradiation would have on the nutritional content, the organoleptic properties and the pigment of the fruit

  16. 21 CFR 874.5370 - Tongs antichoke device.

    Science.gov (United States)

    2010-04-01

    ... airway in a blind manner to grasp and extract foreign objects, and a stainless steel forceps with spoon ends that is inserted under tactile guidance to grasp and extract foreign objects from the airway. (b... grasp and remove foreign objects that obstruct a patient's airway to prevent asphyxiation of the patient...

  17. Efficient Sonogashira and Suzuki-Miyaura coupling reaction ...

    Indian Academy of Sciences (India)

    with short reaction time and good-to-excellent product yield. Keywords. Electrochemistry .... We started optimization study with variety of solvents (table 1, entry 1–6) ... did not show any significant increase in product yield. (table 1, entries 8 and ...

  18. Possible Outflow Formation in the Central Engine of GRBs Tong Liu ...

    Indian Academy of Sciences (India)

    be geometrically thick when advection becomes dominant. In this paper, we dis- cuss the enhanced neutrino annihilation luminosity and the possible formation of the accretion flow. 2. Results. Figure 1(a) shows that there exists a narrow empty funnel along the rotation axis. Thus the volume above the disk shrinks and the ...

  19. Therapeutic effect of He-Wei-Tong-Xie decoction on acute ...

    African Journals Online (AJOL)

    Gastrointestinal function scores (stomach ache, abdominal distension, borborygmus and defecation), and ..... and erosion of digestive tract mucosa, resulting in the damage of ... and reproduction in any medium, provided the original work is ...

  20. Enhancements to the Tonge-Ramesh Ceramic Failure Model for Use in Eulerian Simulations

    Science.gov (United States)

    2016-09-14

    that the model can be used for impact events where there is moderate deformation of the materials using a material point method numerical scheme.1,2 The...8) Once damage reaches a critical level , Dc, the granular flow phase of the material model is activated. In the granular flow phase, there is a...neighborhood of a crack σe depends on both the macroscopic stress (Gauss point or material point stress, σ) and the damage level . 10 Approved for

  1. ‘Dink voordat jy praat’: Die krag van die tong by Philo en Jakobus

    Directory of Open Access Journals (Sweden)

    Gert J. Steyn

    2015-09-01

    Full Text Available ‘Think before you speak’: The power of the tongue by Philo and James. It is appropriate to reflect on the ability of language in pursuing and establishing peace. This contribution briefly explores the Jewish Wisdom literature, the Jewish-Hellenistic philosophy of the corpus Philonicum and the wisdom genre of James 3 as valuable sources on the power of the tongue. At least five practical guidelines regarding speech and its role in the creation of peace are deduced from these three collections of literature: the tongue might be small, but its effects are powerful; believers’ speech should be characterised by truth and honesty; there are times when one needs to speak up and openly; but there are also times that one should be cautious and rather keep quiet; wisdom is needed in exercising the ability to differentiate when to speak and when to keep quiet. It is important, however, to develop the ability to distinguish when to speak and when to keep quiet.

  2. Tong et al., Okmen and Turkcan Afr J Tradit Complement Altern Med ...

    African Journals Online (AJOL)

    cadewumi

    (NGS) and 0.5% Triton X-100. Then the samples were incubated in the primary antibody. The rabbit polyclonal antibody, which was raised in the rat against 21, amino acid peptide corresponding to the C-terminus of the rat capsaicin receptor protein (Zhongshan Goldenbridge Biotechnology. Co. Ltd, China), was used at ...

  3. Microfiltration Process by Inorganic Membranes for Clarification of TongBi Liquor

    Directory of Open Access Journals (Sweden)

    Minyan Huang

    2012-02-01

    Full Text Available Membrane separation is an alternative separation technology to the conventional method of filtration. Hence, it has attracted use in the purification and concentration of Chinese Herbal Medicine Extracts (CHMEs. The purpose of this work was to study the process of microfiltration of Tongbi liquor (TBL, a popular Chinese herbal drink, using ceramic membranes. Zirconium oxide and aluminum oxide membranes with pore mean sizes of 0.2 μm and 0.05 μm, respectively, are used for comparisons in terms of flux, transmittance of the ingredients, physical-chemical parameters, removal of macromolecular materials and fouling resistance. The results show that 0.2 μm zirconium oxide membrane is more suitable. The stable permeate flux reaches 135 L·h−1·m−2, the cumulative transmittance of the indicator is 65.53%. Macromolecular materials, such as starch, protein, tannin, pectin and total solids were largely eliminated in retentate after filtration using 0.2 μm ZrO2 ceramic membrane, resulting in clearer TBL. Moreover, this work also reveals that continuous ultrasound could strengthen membrane process that the permeate flux increases significantly. This work demonstrates that the purification of CHME with ceramic membranes is possible and yielded excellent results.

  4. A Plan to Renovate the Tong Fang-Xiang Lane in Suzhou City

    Institute of Scientific and Technical Information of China (English)

    1990-01-01

    <正> With the perception of concept of land value and the improving standards of city management,the traditionalthinking and concept of planning requires innovation.This article presents the investigation planners carried out in the reform of planning concept based on the experi-ences of other countries and with special reference to the situation in China.It is hoped that this would provide op-portunities for further discussions among planners in the country.

  5. Tong and Yu et al., Afr J Tradit Complement Altern Med. (2016) 13(1 ...

    African Journals Online (AJOL)

    PROF ADEWUNMI

    Serial dilution was undertaken using sterile distilled water and the inoculated normal saline. ... A multiple disc containing the antibiotics was placed on the surface of the agar. The multi ... sanitary risk there may be by hand contact with patients.

  6. Documentation of the Tonge-Ramesh Material Model for Release 2015-06-05-152756

    Science.gov (United States)

    2015-10-01

    on the Kayenta yield and flow surface (Brannon et al. 2009). The yield surface is written in terms of the Lode invariants. For a Cauchy stress tensor σ...codes that do not accurately track the temperature being fed into the UMAT. 23 References Brannon RM, Fossum A, Strack O. KAYENTA : Theory and user’s guide

  7. Tong et al., Afr J Tradit Complement Altern Med., (2017) 14 (5): 56 ...

    African Journals Online (AJOL)

    resistance of the strains is related to their abilities of biofilm formation. 2. Biofilm formation capabilities of herb-resistant strains show different responses to the presence of glucose. 3. luxS encoded AI-2 is not essential for biofilm formation in this ...

  8. De ongetemde tong : Opvattingen over zondige, onvertogen en misdadige woorden in het Middelnederlands (1300-1550)

    NARCIS (Netherlands)

    Veldhuizen, M.D.

    2013-01-01

    This book examines medieval notions of harmful speech conduct (1300-1550) in Western Europe as reflected in Middle Dutch textual sources. Insights are drawn from an in-depth analysis of Middle Dutch ecclesiastical, secular-ethical, and legal textual sources of harmful speech. I aim to make a

  9. Método Suzuki: El método de la lengua materna

    OpenAIRE

    Vides, Graciela

    2012-01-01

    Es un artículo de divulgación del citado método de enseñanza musical. Sintetiza las bases filosóficas que lo sustentan y expone los puntos principales de su puesta en práctica. Bachillerato de Bellas Artes "Prof. Francisco A. De Santo"

  10. A Trotter-Suzuki approximation for Lie groups with applications to Hamiltonian simulation

    Science.gov (United States)

    Somma, Rolando D.

    2016-06-01

    We present a product formula to approximate the exponential of a skew-Hermitian operator that is a sum of generators of a Lie algebra. The number of terms in the product depends on the structure factors. When the generators have large norm with respect to the dimension of the Lie algebra, or when the norm of the effective operator resulting from nested commutators is less than the product of the norms, the number of terms in the product is significantly less than that obtained from well-known results. We apply our results to construct product formulas useful for the quantum simulation of some continuous-variable and bosonic physical systems, including systems whose potential is not quadratic. For many of these systems, we show that the number of terms in the product can be sublinear or even subpolynomial in the dimension of the relevant local Hilbert spaces, where such a dimension is usually determined by the energy scale of the problem. Our results emphasize the power of quantum computers for the simulation of various quantum systems.

  11. Aqueous-phase Suzuki-Miyaura cross-coupling reactions of free halopurine bases

    Czech Academy of Sciences Publication Activity Database

    Čapek, Petr; Vrábel, Milan; Hasník, Zbyněk; Pohl, Radek; Hocek, Michal

    -, č. 20 (2006), s. 3515-3526 ISSN 0039-7881 R&D Projects: GA ČR(CZ) GA203/05/0043 Institutional research plan: CEZ:AV0Z40550506 Keywords : purines * cross-coupling * reactions Subject RIV: CC - Organic Chemistry Impact factor: 2.333, year: 2006

  12. Dinuclear Tetrapyrazolyl Palladium Complexes Exhibiting Facile Tandem Transfer Hydrogenation/Suzuki Coupling Reaction of Fluoroarylketone

    KAUST Repository

    Dehury, Niranjan; Maity, Niladri; Tripathy, Suman Kumar; Basset, Jean-Marie; Patra, Srikanta

    2016-01-01

    Herein, we report an unprecedented example of dinuclear pyrazolyl-based Pd complexes exhibiting facile tandem catalysis for fluoroarylketone: Tetrapyrazolyl di-palladium complexes with varying Pd-Pd distances efficiently catalyze the tandem reaction

  13. JiaZhang Dui ErTong FaZhan TongBan GuanXi De ZuoYong (The Role of Parents in the Development of Peer Group Competence). ERIC Digest.

    Science.gov (United States)

    Moore, Shirley G.

    Among studies that have examined the relationship between parenting styles and children's development of social skills, the research of Diana Baumrind is noteworthy. In several studies, she has identified authoritarian, permissive, and authoritative parenting styles, which differ on the dimensions of nurturance and parental control. Authoritarian…

  14. “Chinos masones”. La logia Chee Kung Tong 致公堂 en México

    Directory of Open Access Journals (Sweden)

    José Luis Chong

    2015-01-01

    Full Text Available La llegada de los inmigrantes chinos a México a partir de la década de 1870, fue promovida por empresarios y gobierno para hacer frente a la gran demanda de mano de obra, originada por las fuertes inversiones en la minería, ferrocarriles y la agricultura, sin embargo a partir del inicio de la Revolución mexicana, estos trabajadores fueron sistemáticamente atacados, sus propiedades confiscadas y casi en su totalidad deportados. Durante la llamada “campaña anti-chinos”, la logia masónica Chee Kung Tong致公堂les brindó protección y apoyo, funcionando con las mismas características de las ancestrales sociedades secretas en China.

  15. New and Noteworthy Records of Mosses from Doi (Mt. Inthanon, Chiang Mai, Chom Tong District, Northern Thailand

    Directory of Open Access Journals (Sweden)

    Printarakul Narin

    2013-07-01

    Full Text Available Mosses new to Thailand (35 species in 29 genera and new to Doi Inthanon (6 species in 6 genera are reported based on collections made by the authors. Austinia tenuinervis var. micholitzii W. R. Buck & H. A. Crum, Brotherella nictans (Mitt. Broth., Chionostomum hainanensis B. C. Tan & Y. Jia, Clastobryopsis muelleri (Dixon Tixier, Trichosteleum stigmosum Mitt., Micralsopsis complanata (Dixon W. R. Buck, and Fissidens schwabei Nog. are fully illustrated.

  16. Palladium-catalyzed domino C,N-coupling/carbonylation/Suzuki coupling reaction: an efficient synthesis of 2-aroyl-/heteroaroylindoles.

    Science.gov (United States)

    Arthuis, Martin; Pontikis, Renée; Florent, Jean-Claude

    2009-10-15

    A convenient one-pot synthesis of 2-aroylindoles using a domino palladium-catalyzed C,N-coupling/carbonylation/C,C-coupling sequence is described. The reaction involved easily prepared 2-gem-dibromovinylanilines and boronic acids under carbon monoxide. Optimized reaction conditions allowed the construction of a wide variety of highly functionalized 2-aroyl-/heteroaroylindoles in satisfactory yields.

  17. Penerapan Metode AHP Dan TOPSIS Untuk Mengevaluasi Pemohon Kredit Suku Cadang Motor Suzuki (Studi Kasus : PT. Riau Jaya Cemerlang Pekanbaru

    Directory of Open Access Journals (Sweden)

    Mursalim Mursalim

    2017-01-01

    Full Text Available AbstrakDalam pemberian kredit kepada pelanggan banyak hal perlu dipertimbangkan agar keputusan yang diambil tidak salah. Biasanya dilakukan pengumpulan beberapa persyaratan administrasi serta melakukan penilaian terhadap jaminan seperti aset yang dimiliki, nilai ekonomi dan beberapa pertimbangan lainnya, sehingga proses pengambilan keputusan butuh waktu lama. Dalam penelitian ini dibangun suatu sistem pendukung keputusan untuk menentukan pemberian kredit kepada konsumen dengan menerapkan dua metode yaitu Analytical Hierarchy Process (AHP. Kata kunci: AHP, Kredit, Suku Cadang. AbstractIn granting credit to customers a lot of things need to be considered so that the decisions are not wrong. Usually done some administrative requirements gathering and assessment of collateral as assets, economic value and some other considerations, so that the decision-making process takes a long time. In this study constructed a decision support system for determining lending to consumers by applying two methods: Analytical Hierarchy Process (AHP. Keywords: AHP,  Credit, Parts.

  18. Modular Stereoselective Synthesis of (1 -> 2)-C-Glycosides based on the sp(2)-sp(3) Suzuki-Miyaura Reaction

    Czech Academy of Sciences Publication Activity Database

    Oroszová, B.; Choutka, J.; Pohl, Radek; Parkan, K.

    2015-01-01

    Roč. 21, č. 19 (2015), s. 7043-7047 ISSN 0947-6539 Grant - others:GA ČR(CZ) GPP207/12/P713; GA ČR(CZ) GA15-17572S Institutional support: RVO:61388963 Keywords : C-disaccharides * C-glycosides * diastereoselectivity * Mitsunobu reaction * sp(2)-sp(3) coupling Subject RIV: CC - Organic Chemistry Impact factor: 5.771, year: 2015

  19. The introduction of high-throughput experimentation methods for Suzuki-Miyaura coupling reactions in University education

    NARCIS (Netherlands)

    Hoogenboom, R.; Meier, M.A.R.; Schubert, U.S.

    2005-01-01

    Use of high-throughput experimentation is becoming common in industry. To prepare students to work with those novel techniques in their future careers, the utilization of an automated synthesis robot was integrated into an undergraduate research project. The practical course included performing a

  20. 77 FR 75972 - Foreign-Trade Zone 26 - Atlanta, Georgia Notification of Proposed Production Activity Suzuki Mfg...

    Science.gov (United States)

    2012-12-26

    ... assemblies, guides, electrical components, coils, sensors and related assemblies, resistors, horns, relays, switches, lighting equipment, radiators, electronic control units, stampings, other parts of ATVs, brake...

  1. Diamond functionalization with light-harvesting molecular wires: improved surface coverage by optimized Suzuki cross-coupling conditions

    Czech Academy of Sciences Publication Activity Database

    Yeap, W. S.; Bevk, D.; Liu, X.; Krýsová, Hana; Pasquarelli, A.; Vanderzande, D.; Lutsen, L.; Kavan, Ladislav; Fahlman, M.; Maes, W.; Haenen, K.

    2014-01-01

    Roč. 4, AUG 2014 (2014), s. 42044-42053 ISSN 2046-2069 R&D Projects: GA ČR GA13-31783S Institutional support: RVO:61388955 Keywords : Functionalizations * Light-harvesting * Molecular wires Subject RIV: CG - Electrochemistry Impact factor: 3.840, year: 2014

  2. Planar geometry of 4-substituted-2,2'-bipyridines synthesized by Sonogashira and Suzuki cross-coupling reactions

    Energy Technology Data Exchange (ETDEWEB)

    Luong Thi, T. T., E-mail: thuyltt@hnue.edu.vn; Nguyen Bich, N.; Nguyen, H. [Hanoi National University of Education, Chemistry Department (Viet Nam); Van Meervelt, L., E-mail: luc.vanmeervelt@chem.kuleuven.be [KU Leuven, Chemistry Department (Belgium)

    2015-12-15

    Two 4-substituted 2,2'-bipyridines, namely 4-(ferrocenylethynyl)-2,2'-bipyridine (I) and 4-ferrocenyl-2,2'-bipyridine (II) have been synthesized and fully characterized via single-crystal X-ray diffraction and {sup 1}H and {sup 13}C NMR analyses. The π-conjugated system designed from 2,2'-bipyridine modified with the ferrocenylethynyl and ferrocenyl groups shows the desired planarity. In the crystal packing of I and II, the molecules arrange themselves in head-to-tail and head-to-head motifs, respectively, resulting in consecutive layers of ferrocene and pyridine moieties.

  3. New air-stable planar chiral ferrocenyl monophosphine ligands: Suzuki cross-coupling of aryl chlorides and bromides

    DEFF Research Database (Denmark)

    Jensen, Jakob Feldthusen; Johannsen, Mogens

    2003-01-01

    GraphicA novel class of planar chiral electron-rich monophosphine ligands has been developed. The modular design allows a short and efficient synthesis of an array of aryl-ferrocenyl derivatives carrying the donating bis(dicyclohexyl)phosphino moiety. These new ligands have successfully been...

  4. A Chinese medicine warm compress (Wen Jing Zhi Tong Fang), combined with WHO 3-step analgesic ladder treatment for cancer pain relief: A comparative randomized trial.

    Science.gov (United States)

    Cai, Peiling; Li, Liuning; Hong, Hongxi; Zhang, Liwen; He, Chunxia; Chai, Xiaoshu; Liu, Bai; Chen, Zhijian

    2018-03-01

    This study aimed to assess the effectiveness of Chinese medicine warm compress (CMWC) on back meridians in relieving cancer pain, reducing adjuvant analgesic doses and adverse reactions, and improving the quality of life (QOL). A total of 62 patients (age range 39-82 years) diagnosed with a malignant tumor and suffering from cancer-related pain were randomly divided into a treatment group (group A) and a control group (group B) (n = 31 for each). The patients in both groups were administered appropriate drugs for 2 cycles of 7-day treatments according to the World Health Organization (WHO) 3-step ladder for cancer pain relief in adults. In addition, a CMWC was given to patients in group A. Pain relief was assessed using the visual analogue scale (VAS) at various time points before and after interventions in each group. Alteration of analgesic doses, adverse reactions, performance status (PS), and QOL were evaluated and any differences between groups A and B evaluated. VAS scores at various time points after treatment were significantly decreased compared with the baseline level in group A. Overall response rate was significantly improved in group A compared with group B (70.97% vs 29.03%, P pain relief efficacy in various locations were found in group A after treatment vs before treatment (P pain with reduced doses, less adverse reactions, and improved QOL.

  5. 77 FR 6782 - In the Matter of: Kok Tong Lim, a/k/a Thomas Lim Blk 258A Compassvale Road #07-551 Singapore...

    Science.gov (United States)

    2012-02-09

    ... Thomas Lim Blk 258A Compassvale Road 07-551 Singapore 541258; Order Denying Export Privileges On October...'') of Singapore, pled guilty to one count of violating the International Emergency Economic Powers Act..., a/k/a Thomas Lim, with the last known address at: Blk 258A,Compassvale Road 07-551, Singapore 541258...

  6. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. Makoto Kobayashi. Articles written in Pramana – Journal of Physics. Volume 69 Issue 6 December 2007 pp 981-987 Tracking and Vertexing. A beam test of prototype time projection chamber using micro-pattern gas detectors at KEK · Makoto Kobayashi on behalf of part of the ...

  7. Physiological and Psychological Characteristics of Successful Combat Controller Trainees

    Science.gov (United States)

    2010-08-01

    here. Reaction Time. Eye-hand reaction speeds were measured on the Makoto Sports Arena (Makoto USA, Centennial , CO) in reactive and proactive modes... depression , self- consciousness, immoderation, and vulnerability. Individuals that score low in this area are less easily upset and are less emotionally

  8. The Social Determinants of Attitudes towards Nuclear Energy:Examination for the Value Mediated Mechanism(Special Issue Dedicated to Professor SUZUKI Tomihisa)

    OpenAIRE

    阪口, 祐介

    2016-01-01

    Since the 2011 Fukushima Daiichi nuclear power plant accident, the negative opinion to nuclear power plant has increased and the political debates over the pros and cons of nuclear energy has been activated. This paper attempts to reveal empirically the social determinants of attitudes towards nuclear energy. We focus on generation, gender, and social stratification as the determinants, and examine for the value mediated mechanism. Previous researches have indicated that women tend to have ne...

  9. Synthesis and cytostatic activity of substituted 6-phenylpurine bases and nucleosides: application of the Suzuki-Miyaura cross-coupling reactions of 6-chloropurine derivatives with phenylboronic acids

    Czech Academy of Sciences Publication Activity Database

    Hocek, Michal; Holý, Antonín; Votruba, Ivan; Dvořáková, H.

    2000-01-01

    Roč. 43, č. 9 (2000), s. 1817-1825 ISSN 0022-2623 R&D Projects: GA ČR GA203/98/P027; GA ČR GV203/96/K001 Institutional research plan: CEZ:AV0Z4055905 Subject RIV: CC - Organic Chemistry Impact factor: 4.134, year: 2000

  10. Water-dispersable hybrid Au-Pd nanoparticles as catalysts in ethanol oxidation, aqueous phase Suzuki-Miyaura and Heck reactions

    KAUST Repository

    Song, Hyon Min; Moosa, Basem; Khashab, Niveen M.

    2012-01-01

    The catalytic activities of water-dispersable Au@Pd core-shell nanoparticles (NPs) and Au-Pd alloy NPs were examined. There is growing interest in Au-Pd hybridized NPs in a supported matrix or non-supported forms as catalysts in various reactions

  11. Catalytic activity of some oxime-based Pd(II-complexes in Suzuki coupling of aryl and heteroaryl bromides in water

    Directory of Open Access Journals (Sweden)

    Kamal M. Dawood

    2017-05-01

    Full Text Available The catalytic activity of four Pd(II-complexes of benzoazole-oximes was extensively studied in Suzuki–Miyaura C–C cross coupling reactions in water, as an eco-friendly green solvent, under both thermal heating as well as microwave irradiation conditions. The cross-coupling reactions included different activated and deactivated aryl- or heteroaryl-bromides with several arylboronic acids. The protected oxime-complexes were found to be more efficient than the free ones.

  12. Sample Set (SE): SE58 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available greatly facilitates data interpretation, quality control and method comparisons. Henning Redestig, Makoto K...obayashi, Kazuki Saito, Miyako Kusano Henning R et al. (2011) Analytical Chemistry 83: 5645-5651 ...

  13. Redescription of 13 holotypes of Rheocricotopus Brundin, 1956 (Diptera: Chironomidae) from the Sino-Indian Region.

    Science.gov (United States)

    Fu, Yue; Huang, Jingli; Liu, Wenbin; Fang, Xiangliang; Wang, Xinhua

    2016-05-24

    Thirteen holotypes of the orthoclad genus Rheocricotopus from Sino-Indian Region: R. (Psilocricotopus) hidakadeeus Sasa & Suzuki, R. (P.) isigadeeus Sasa & Suzuki, R. (P.) kurocedeus Sasa, R. (P.) tokarakeleus Sasa & Suzuki, R. (P.) tobatervicesimus Kikuchi & Sasa, R. (Rheocricotopus) inaquereus Sasa, Kitami & Suzuki, R. (R.) inaxeyeus Sasa, Kitami & Suzuki, R. (R.) shoufukusecundus Sasa, R. (R.) tamahumeralis Sasa, R. (R.) tatequintus Sasa, R. (R.) tedorisecundus Sasa, R. (R.) togapeniculus Sasa & Okazawa and R. (R.) yakulemeus Sasa & Suzuki are re-examined and illustrated, Some additional descriptions, corrections and a key of these thirteen holotypes are given.

  14. Sample Set (SE): SE17 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available Sakurai 1, Hideyuki Suzuki 1, Tatsuya Suzuki 2, Daisuke Shibata 1, 1: Kazusa DNA Research Institute, 2: Chiba Prefectural Agriculture Research Center Direct Submittion version 1 ...

  15. Sample Set (SE): SE12 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available moto 1, Nozomu Sakurai 1, Hideyuki Suzuki 1, Tatsuya Suzuki 2, Daisuke Shibata 1, 1: Kazusa DNA Research... Institute, 2: Chiba Prefectural Agriculture Research Center Direct Submittion version 2 ...

  16. Maghemite decorated with ultra-small palladium nanoparticles (γ-Fe2O3–Pd): applications in the Heck–Mizoroki olefination, Suzuki reaction and allylic oxidation of alkenes

    Science.gov (United States)

    A nanocatalyst comprising ultra-small Pd/PdO nanoparticles (precipitation protocol using inexpensive raw materials and was deployed successfully in various significant synthetic transformations, namely the Heck–Mizoroki olefinati...

  17. Chemoselective Synthesis of 4,5-Diarylpyrrolo[2,3-d]pyrimidines (6,7-Diaryl-7-deazapurines) by Consecutive Suzuki and Liebeskind-Srogl Cross-Couplings

    Czech Academy of Sciences Publication Activity Database

    Krömer, M.; Klečka, Martin; Slavětínská, Lenka; Klepetářová, Blanka; Hocek, Michal

    2014-01-01

    Roč. 2014, č. 32 (2014), s. 7203-7210 ISSN 1434-193X Grant - others:GA ČR(CZ) GAP207/12/0205 Institutional support: RVO:61388963 Keywords : synthetic methods * chemoselectivity * cross - coupling * palladium * nitrogen heterocycles Subject RIV: CC - Organic Chemistry Impact factor: 3.065, year: 2014

  18. Maghemite decorated with ultra-small palladium nanoparticles (γ-Fe2O3–Pd): applications in the Heck–Mizoroki olefination, Suzuki reaction and allylic oxidation of alkenes

    Science.gov (United States)

    A nanocatalyst comprising ultra-small Pd/PdO nanoparticles (<5 nm) supported on maghemite was prepared by a co-precipitation protocol using inexpensive raw materials and was deployed successfully in various significant synthetic transformations, namely the Heck–Mizoroki olefinati...

  19. Stemcell Information: SKIP000144 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ... Makoto Otsu --Huan-Ting Lin 大津 真--Huan-Ting Lin University of Tokyo, Institute of Medical Science--U...niversity of Tokyo, Institute of Medical Science 東京大学医科学研究所--東京大学医科学研究所 Universit...y of Tokyo, Institute of Medical Science 東京大学医科学研究所 Makoto Otsu 大津 真 Not Available Riken BRC 理研BRC http://www.brc.riken.jp/lab/cell/english/patient_specific_ips.shtml ...

  20. Stemcell Information: SKIP000145 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ... Makoto Otsu --Huan-Ting Lin 大津 真--Huan-Ting Lin University of Tokyo, Institute of Medical Science--Un...iversity of Tokyo, Institute of Medical Science 東京大学医科学研究所--東京大学医科学研究所 University... of Tokyo, Institute of Medical Science 東京大学医科学研究所 Makoto Otsu 大津 真 Not Available Riken BRC 理研BRC http://www.brc.riken.jp/lab/cell/english/patient_specific_ips.shtml ...

  1. Estrogen-mediated hemangioma-derived stem cells through estrogen receptor-? for infantile hemangioma

    OpenAIRE

    Zhang, Ling; Wu, Hai Wei; Yuan, Weien; Zheng, Jia Wei

    2017-01-01

    Ling Zhang,1 Hai Wei Wu,1 Weien Yuan,2 Jia Wei Zheng1 1Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute, 2School of Pharmacy, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Background: Infantile hemangiomas (IHs) are the most common benign vascular tumor of infancy. They occur more frequently in female infants....

  2. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Channelrhodopsins provide a breakthrough insight into strategies for curing blindness · Hiroshi Tomita Eriko Sugano Hitomi Isago Makoto Tamai · More Details Abstract Fulltext PDF. Photoreceptor cells are the only retinal neurons that can absorb photons. Their degeneration due to some diseases or injuries leads to ...

  3. Spontaneous rupture of the middle colic artery resulting in delayed ...

    African Journals Online (AJOL)

    mission for three days after delivery due to raised blood pressure which was controlled using antihypertensives. The baby weighed 3.8 kg with good Apgar score. ... Osamu C, Hiroshi K, Makoto S, Soichiro Y, Hiroyuki. K, Yasumasa K, Hiroyasu M. Spontaneous rupture of. Dissecting Aneurysm of the Middle colic Artery. Tokai.

  4. A beam test of prototype time projection chamber using micro ...

    Indian Academy of Sciences (India)

    High Energy Accelerator Organization (KEK), Tsukuba 305-0801, Japan. E-mail: makoto.kobayashi.exp@kek.jp. Abstract. We conducted a series of beam tests of prototype TPCs for the international linear collider (ILC) experiment, equipped with an MWPC, a MicroMEGAS, or GEMs as a readout device. The prototype ...

  5. Cálculo dos custos do reprocessamento de pinças de uso único utilizadas em cirurgia vídeo-assistida Cálculo de los costos del reprocesamiento de pinzas de uso único utilizadas en cirugía video-asistida Calculation of the reprocessing costs of single-use tongs used in video-assisted surgeries

    Directory of Open Access Journals (Sweden)

    Eliane Molina Psaltikidis

    2006-06-01

    Full Text Available O trabalho objetivou desenvolver proposta metodológica para cálculo dos custos do reprocessamento de pinças de cirurgia vídeo-assistida de uso único. O reuso freqüente desses artigos ocorre pelo alto custo, entretanto, poucos estudos foram desenvolvidos a respeito desse enfoque. Elaborou-se um fluxograma com cada fase de reprocessamento, permitindo identificação dos componentes dos custos quanto à mão-de-obra, materiais e gastos indiretos. Pautado nesses dados, pôde-se construir a proposta metodológica para o cálculo de custos, baseada no método de custeio por absorção, incluindo a planilha para coleta de dados.El trabajo tuvo como objetivo desarrollar propuesta metodológica para el cálculo de los costos del reprocesamiento de pinzas de cirugía video-asistida de uso único. El uso frecuente de esos artículos ocurre por el alto costo, no obstante, pocos estudios fueron desarrollados respecto a ese enfoque. Se elaboró un fluxograma con cada fase del reprocesamiento, permitiendo la identificación de los componentes de los costos en cuanto a la mano de obra, materiales y gastos indirectos. Teniendo como pauta esos datos, se puede construir la propuesta metodológica para el cálculo de costos, con base en el método de costeo por absorción, incluyendo la planilla para recolección de datos.The frequent reuse of disposable forceps instruments is justified by their high cost. However, few studies have been carried out on this topic. The objective of this study was to develop a methodological proposal for calculating the reprocessing costs for these instruments used in video-assisted surgery. A flowchart was developed for each phase of the reprocessing. This allowed subsequent identification of the cost components in terms of labor, materials and indirect expenses. From these data, a methodological proposal for cost calculation could be created, based on the Full Absorption Costing Method, including the spreadsheet for data collection.

  6. Maternal high-fat diet during pregnancy and lactation affects hepatic ...

    Indian Academy of Sciences (India)

    Department of Endocrinology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Institute of Pediatric Research, Shanghai, China; 3Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai ...

  7. Cani kunagine laulja Tallinnas. Led Zeppelin koguneb taas? Ian Brown müüb oma maja liiga kallilt

    Index Scriptorium Estoniae

    2002-01-01

    Damo Suzuki ja tema uue ansambli Damo Suzuki Network esinemisest Von Krahli Teatri baaris 21.oktoobril. Led Zeppelini plaanist korraldada järgmisel aastal kontserttuur mööda USAd. Ansambli Stone Roses kunagise solisti Ian Browni suvemaja müügist Põhja-Walesis Llithfaenis

  8. Design, synthesis and characterization of 1H-pyridin-4-yl-3,5 ...

    Indian Academy of Sciences (India)

    Keywords. 1H-pyridin-4-yl-3,5-disubstituted indazoles; Suzuki reaction; Akt kinase activity. 1. Introduction. In organic synthesis, Palladium-catalysed new carbon– carbon bond formation from aryl halides with organo boronic acids via Suzuki coupling reaction has been proved to be an important method. The 2010 Nobel.

  9. A Density-Ratio Approach to Machine Learning

    Science.gov (United States)

    2011-04-20

    28/29, 10587 Berlin, Germany. buenau@cs.tu-berlin.de Taiji Suzuki The University of Tokyo 7-3-1 Hongo , Bunkyo-ku, Tokyo 113-8656, Japan. s-taiji...Computation, to appear. Least-squares Independent Component Analysis∗ Taiji Suzuki Department of Mathematical Informatics, The University of Tokyo 7-3-1 Hongo

  10. (Ciliophora: Peritrichia) from the urinary bladder of Bufo gutturalis

    African Journals Online (AJOL)

    1988-09-07

    Sep 7, 1988 ... vesicola Suzuki, 1950 from Rana rugosa (Suzuki 1950). The question arises whether T. dampanula sp. n. may possibly be the same species as observed by Fantham. (1924) in the urinary bladder of B. regularis, i.e. T. bufonis. Owing to the fact that none of the character- istics provided by Fantham (1924) ...

  11. Onboard Flow Sensing For Downwash Detection and Avoidance On Small Quadrotor Helicopters

    Science.gov (United States)

    2015-01-01

    onboard computers, one for flight stabilization and a Linux computer for sensor integration and control calculations . The Linux computer runs Robot...Hirokawa, D. Kubo , S. Suzuki, J. Meguro, and T. Suzuki. Small uav for immediate hazard map generation. In AIAA Infotech@Aerospace Conf, May 2007. 8F

  12. Arachidonic Acid Metabolism in the Nervous System; Physiological and Pathological Significance. Annals of the New York Academy of Science. Volume 5

    Science.gov (United States)

    1989-01-01

    488 Primary Structure of Rat Brain Prostaglandin D Synthetase Deduced from the cDNA Sequence. By YOSHIHIRO URADE, AKIHISA NAGATA, YASUHIKO SUZUKI...Synthetase Deduced from the cDNA Sequence YOSHIHIRO URADE,a AKIHISA NAGATA,b YASUHIKO SUZUKI,b YUTAKA FUJII,c AND OSAMU HAYAISHI a aDepartment of Enzymes

  13. The diverse impacts of the great recession

    OpenAIRE

    Makoto Nakajima

    2013-01-01

    The Great Recession had a large negative impact on the U.S. economy. Asset prices, most notably stock and house prices, declined substantially, resulting in a loss in wealth for many American households. In this article, Makoto Nakajima documents how diverse households were affected in a variety of dimensions during the Great Recession, in particular between 2007 and 2009, using newly available data from the 2007-2009 Survey of Consumer Finances. He discusses why it is important to look at th...

  14. Intraocular pressure readings obtained through soft contact lenses using four types of tonometer

    OpenAIRE

    Takenaka J; Kunihara E; Rimayanti U; Tanaka J; Kaneko M; Kiuchi Y

    2015-01-01

    Joji Takenaka,1 Eriko Kunihara,1 Ulfah Rimayanti,2 Junko Tanaka,3 Makoto Kaneko,4 Yoshiaki Kiuchi1 1Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan; 2Faculty of Medicine and Health Sciences, UIN Alauddin Makassar, South Sulawesi, Indonesia; 3Department of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan; 4Graduate Schoo...

  15. Physics Nobel Prize (PNP in 2008

    Directory of Open Access Journals (Sweden)

    José Maria Filardo Bassalo

    2009-08-01

    Full Text Available In this article we will talk about the Nobel Prize in Physics 2008, granted  to  the Japanese  physicists  Yoichiro  Nambu,  Makoto Kobayashi and Toshihide Maskawa,  for  their  discovery  of  the mechanisms involving strong interactions symmetries (quiral, by Nambu, and in weak interactions (charge-parity, by Kobayashi and Maskawa.

  16. Japan. Ogata, 4 others to get Order of Culture

    CERN Multimedia

    2003-01-01

    Makoto Ooka, 72, known for his comments on haiku and tanka poetry; Matazo Kayama, 76, for reviving traditional Japanese painting; Kazuhiko Nishijima, 77, professor emeritus at both the University of Tokyo and Kyoto University, in recognition of his contribution in the field of elementary particle physics (his classification of elementary particles became the basis of quark theory); and Wataru Mori, 77, professor emeritus at the University of Tokyo for his contribution to the study of pathology (1/2 page).

  17. Popmuusika / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2006-01-01

    Uutest heliplaatidest "Walk The Line", "B.B. King & Friends", Green Day "Bullet In A Bible", "It's All Gone Pete Tong O.S.T.", Mogwai "Mr. Beast", Cypress Hill "Greatest Hits From The Bong", Sway "This Is My Demo"

  18. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Screen printing; ferroelectricity; piezoelectricity; nonlinear property. .... Luoyang Institute of Science and Technology, Luoyang 471023, China; Functional Materials Research Laboratory, Tongji University, Shanghai 200092, China; Department of Physics and Materials Science, City University of Hong Kong, Kowloon Tong, ...

  19. Irritable Bowel Syndrome and Complementary Health Practices

    Science.gov (United States)

    ... IBS) in adults: conventional and complementary/alternative approaches. Alternative Medicine Review. 2011;16(2):134–151. Herbal Supplements Shi J, Tong Y, Shen JG, et al. Effectiveness and safety of herbal medicines in the treatment ...

  20. Rode mondslijmvliesafwijkingen

    NARCIS (Netherlands)

    van der Waal, I.

    2011-01-01

    Er zijn diverse afwijkingen van hetmondslijmvlies, het tandvlees en de tong, die zich als een rode verandering presenteren. Deze lopen uiteen van de bekende roodheid bij gingivitis, erythemateuze candidose, erosieve lichen planus en lupus erythematodes tot erythroplakie als mogelijk voorstadiumvan

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 33; Issue 2 ... R & D Center, Morgan-Tan International Center for Life Sciences, Fudan University, ... School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 2 ... School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200030, ... D Center, Morgan-Tan International Center for Life Sciences, Fudan University, Shanghai ...

  3. Genes involved in sex determination process and the influence of ...

    African Journals Online (AJOL)

    DR. & MRS. TONY A. NLEWADIM

    2015-02-04

    Feb 4, 2015 ... Key words: Next-generation sequencing, simple sequence repeats, Rhamdia sp. .... individual genotypes were defined according to the standards of the bands. ..... Wang J, Yu X, Zhao K, Zhang Y, Tong J, Peng Z (2012).

  4. Learning Contracts in Undergraduate Courses: Impacts on Student Behaviors and Academic Performance

    Science.gov (United States)

    2013-04-01

    they "felt bound and obligated by the mutual expectations," and the learning contract motivated them to complete readings on time ( Lemieux , 2001...1974; Huff and Johnson, 1998; Williams and Williams, 1999; Chan and Wai-tong, 2000; Lemieux , 2001; Chyung, 2007; Litchfield, et al., 2007; O’Halloran...were required to sign a contract (e.g. Barlow, 1974; Huff and Johnson, 1998; Williams and Williams, 1999; Chan and Wai-tong, 2000; Lemieux 2001

  5. Development of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer

    OpenAIRE

    Bai,Fang; Yin,You; Chen,Ting; Chen,Jihui; Ge,Meixin; Lu,Yunshu; Xie,Fangyuan; Zhang,Jian; Wu,Kejin; Liu,Yan

    2018-01-01

    Fang Bai,1–3,* You Yin,4,* Ting Chen,1,* Jihui Chen,1 Meixin Ge,2 Yunshu Lu,2 Fangyuan Xie,5 Jian Zhang,1 Kejin Wu,3 Yan Liu1,6 1Department of Pharmacy, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 2Department of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, 3Department of Breast Surgery, Obstetrics and Gynaecology Hospital, Fudan University, Shanghai, 4Department of Neurology, Changzheng...

  6. Diagnostic challenges with acellular bacterial meningitis

    African Journals Online (AJOL)

    tests performed included a non-reactive HIV ELISA and syphilis serology. ... Despite our patient's reduced CSF glucose and raised protein, the inconsistent .... Suzuki W, et al. Cerebrospinal fluid/blood glucose ratio as an indicator for bacterial ...

  7. Molecular identification of Ornithobacterium rhinotracheale in ...

    African Journals Online (AJOL)

    Jane

    2011-08-01

    Aug 1, 2011 ... production in poultry (Suzuki et al., 2010). ORT was reported in the ... medication costs, increased loss rates and poor pro- duction (Ghanbarpour .... Ornithobacterium rhinotracheale in commercial birds in Peru. Avian. Dis., 49: ...

  8. Tuning the Optoelectronic Properties of Vinylene-Linked Donor−Acceptor Copolymers for Organic Photovoltaics

    KAUST Repository

    Ko, Sangwon; Mondal, Rajib; Risko, Chad; Lee, Jung Kyu; Hong, Sanghyun; McGehee, Michael D.; Brédas, Jean-Luc; Bao, Zhenan

    2010-01-01

    -property relationships in organic photovoltaic devices. Both alternating (P) and random copolymers (P1-P4) were prepared via Suzuki and Stille polycondensations, respectively. The cyclopentadithiophene copolymers (P2 and P4) have smaller electrochemical band gaps (1

  9. Stereoselective synthesis of novel highly substituted isochromanone and isoquinolinone-containing exocyclic tetrasubstituted alkenes.

    Science.gov (United States)

    Arthuis, Martin; Pontikis, Renée; Florent, Jean-Claude

    2009-03-06

    An efficient synthetic route toward the synthesis of highly substituted arylethylidene-isoquinolinones/isochromanones is reported. The tandem carbopalladation/Suzuki-Miyaura coupling sequence stereoselectively provided various functionalized polycyclic compounds in moderate to excellent yields.

  10. Micro-tidal dependent phytoplankton C-biomass dynamics over two ...

    African Journals Online (AJOL)

    Micro-tidal dependent phytoplankton C-biomass dynamics over two shallow tropical coral reefs. Shamimtaz Bibi Sadally, Nawsheen Taleb-Hossenkhan, Beatriz Casareto, Yoshimi Suzuki, Ranjeet Bhagooli ...

  11. Protective effect of rhamnopyranosyl vanilloyl isolated from ...

    African Journals Online (AJOL)

    Cai Tian Di Wang in 2013 and authenticated by. Chang-Wu Wang, a ... purchased from Abcam (Cambridge, UK) and ..... Hosaka T, Suzuki F, Kobayashi M, Seko Y, Kawamura Y, ... Han JJ, Ning N. Research progress on pharmacological.

  12. Transition metal complexes bearing NHC ligands substituted with secondary polyfluoroalkyl groups

    Czech Academy of Sciences Publication Activity Database

    Kolaříková, V.; Šimůnek, O.; Rybáčková, M.; Cvačka, Josef; Březinová, Anna; Kvíčala, J.

    2015-01-01

    Roč. 44, č. 45 (2015), s. 19663-19673 ISSN 1477-9226 Institutional support: RVO:61388963 Keywords : complexes * catalysis * Suzuki-Miyaura coupling Subject RIV: CA - Inorganic Chemistry Impact factor: 4.177, year: 2015

  13. A convenient catalyst system for microwave accelerated cross-coupling of a range of aryl boronic acids with aryl chlorides

    Directory of Open Access Journals (Sweden)

    Milton Edward J

    2007-05-01

    Full Text Available Abstract A convenient microwave accelerated cross-coupling procedure between aryl chlorides with a range of boronic acids has been developed. An explanation for the low reactivity of highly fluorinated boronic acids in Suzuki coupling is provided.

  14. Rhodium-Catalyzed Dehydrogenative Borylation of Cyclic Alkenes

    Science.gov (United States)

    Kondoh, Azusa; Jamison, Timothy F.

    2010-01-01

    A rhodium-catalyzed dehydrogenative borylation of cyclic alkenes is described. This reaction provides direct access to cyclic 1-alkenylboronic acid pinacol esters, useful intermediates in organic synthesis. Suzuki-Miyaura cross-coupling applications are also presented. PMID:20107646

  15. 76 FR 63659 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; Cooperative...

    Science.gov (United States)

    2011-10-13

    ... venture are: Ford Motor Company, Dearborn, MI; GM Global Technology Operations, Inc., Detroit, MI; Honda...; Suzuki Motor Corporation, Hamamatsu City, Japan; and Toyota, Aichi, Japan. The general area of P3's...

  16. Pop / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2003-01-01

    Heliplaatidest: Dave Gahan "Paper Monsters", Paddy McAloon "I Trawl the Megahertz", Jukka Gustavson Organ Fusion Band "Between Fire And Ice", Tanel Ruben & Victoria "A Sentimental Call", Opiate "Sometimes", The Mooney Suzuki "Electric Sweat"

  17. Diversity Oriented Synthesis of Natural 2-Arylbenzofuran, Moracin F

    International Nuclear Information System (INIS)

    Yun, So-Ra; Jun, Jong-Gab

    2016-01-01

    Diversity oriented synthesis of natural 2-arylbenzofuran, moracin F (1) has been carried out from the commercially available starting materials using Sonogashira coupling, Suzuki coupling, neutral Al 2 O 3 mediated cyclization, and intramolecular Wittig reaction as key steps.

  18. Esimene valik / Jaakko Valkiainen, Hannu Häyhä, Sampo Korhonen... [jt.

    Index Scriptorium Estoniae

    Valkiainen, Jaakko

    2014-01-01

    Seitse erineva stiili ja suurusega tsiklit algaja mootorratturi jaoks: BMW F 700 GS, Harley-Davidson XL 883 N Iron, Honda CBR 500 R, Kawasaki Ninja 300, KTM Duke 390, Suzuki GW 250 Inazuma, Yamaha FZ8-S

  19. Comments on the paper 'Temperature dependence of bulk modulus and second-order elastic constants' by P.P. Singh and M. Kumar [Physica B 344 (2004) 41

    International Nuclear Information System (INIS)

    Singh, K.S.

    2005-01-01

    Singh and Kumar have questioned the validity of the Mie-Grueneisen equation using an incorrect formulation. The Suzuki equation for thermal expansivity has been expressed by them in terms of thermal pressure using a wrong definition. The formulations already reported in the literature have been rediscovered by them and redesignated as the Kumar formulation. In the present communication we have reinforced the validity of the Mie-Grueneisen EOS using the correct definition of thermal pressure in the Suzuki formulation

  20. Surgical treatment for medically refractory myasthenic blepharoptosis

    OpenAIRE

    Shimizu, Yusuke; Suzuki,Shigeaki; Nagasao,Tomohisa; Ogata,Hisao; Yazawa,Masaki; Suzuki,Norihiro; Kishi,Kazuo

    2014-01-01

    Yusuke Shimizu,1 Shigeaki Suzuki,2 Tomohisa Nagasao,1 Hisao Ogata,1 Masaki Yazawa,1 Norihiro Suzuki,2 Kazuo Kishi1 1Department of Plastic and Reconstructive Surgery, 2Department of Neurology, Keio University School of Medicine, Tokyo, JapanPurpose: Currently, only a few reports have recommended surgery as a suitable treatment for blepharoptosis associated with myasthenia gravis. The present study aims to introduce our surgical criteria, surgical options, outcomes, and precautions for medicall...

  1. Evaluation of subcooled critical heat flux correlations for tubes with and without internal twisted tapes

    International Nuclear Information System (INIS)

    Inasaka, F.; Nariai, H.

    1996-01-01

    Eleven correlations and models for critical heat flux (CHF) of subcooled flow boiling in water were evaluated. Both a direct substitution method (DSM) and a heat balance condition method (HBM) were compared in the evaluations. The HBM was recommended as a better prediction method in the present study. For straight tubes under uniform heating conditions, the correlations of the Gunther, Knoebel, modified Tong, W-2, and Tong-75, and also the Celata and Weisman-Pei models were confirmed to give reasonably good predictions. Among them, the Celata model was the best with respect to accuracy. For swirl flow under uniform heating conditions, Tong-75-I (involving modification of the water velocity parameter) and Nariai-Inasaka correlations were confirmed to give reasonably good predictions, even though their predictions were too low for the CHF under non-uniform heating conditions. (orig.)

  2. Automated Sample Exchange Robots for the Structural Biology Beam Lines at the Photon Factory

    International Nuclear Information System (INIS)

    Hiraki, Masahiko; Watanabe, Shokei; Yamada, Yusuke; Matsugaki, Naohiro; Igarashi, Noriyuki; Gaponov, Yurii; Wakatsuki, Soichi

    2007-01-01

    We are now developing automated sample exchange robots for high-throughput protein crystallographic experiments for onsite use at synchrotron beam lines. It is part of the fully automated robotics systems being developed at the Photon Factory, for the purposes of protein crystallization, monitoring crystal growth, harvesting and freezing crystals, mounting the crystals inside a hutch and for data collection. We have already installed the sample exchange robots based on the SSRL automated mounting system at our insertion device beam lines BL-5A and AR-NW12A at the Photon Factory. In order to reduce the time required for sample exchange further, a prototype of a double-tonged system was developed. As a result of preliminary experiments with double-tonged robots, the sample exchange time was successfully reduced from 70 seconds to 10 seconds with the exception of the time required for pre-cooling and warming up the tongs

  3. Stemcell Information: SKIP000278 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available man bFGF ... Negative ... Yes ... Natsumi Shimizu 清水 なつみ RIKEN BioResource Center 理化学研究所バイオリソースセンタ...ー RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村 幸夫 Available--Avai...lable--Available RIKEN BioResource Center--Makoto Yazaki(Nagoya City University)--iPS Academia Japan,Inc. 理化学

  4. Frequency–magnitude distribution of -3.7 < M(subW) < 1 mining-induced earthquakes around a mining front and b value invariance with post-blast time

    CSIR Research Space (South Africa)

    Naoi, M

    2014-10-01

    Full Text Available Geophysics Frequency–Magnitude Distribution of -3.7 B MW B 1 mining-induced earthquakes around a mining front and b value invariance with post-blast time Makoto Naoi,1 Masao Nakatani,1 Shigeki Horiuchi,2 Yasuo Yabe,3 Joachim Philipp,4 Thabang Kgarume... Ogasawara 11 1 Earthquake Research Institute, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. E-mail: naoi@eri.u-tokyo.ac.jp 2 Home Seismometer Corp., 4-36, Uenohara, Shirakawa, Fukushima 961-0026, Japan. 3 Research Center...

  5. Jaapani graafika Tallinnas

    Index Scriptorium Estoniae

    2003-01-01

    Ku galeriis jaapani kaasaegse graafika näitus "Living Faces in Tallinn". Kouichi Kitamura kujundatud väljapanek tutvustab rühmituse Printsaurus kunstnike töid. Adamson-Ericu muuseumis näitus "300 aastat Jaapani puulõike traditsiooni. Ukiyo-e puulõiked meister Keizo Sato töökojast". 12. ja 13 IX esinevad näitusel Keizo Sato, tema assistent Makoto Nakayama, puulõikemeister Hiroshi Fujizawa ja ukiyo-e uurija kunstnik Tuula Moilanen. 12. IX loengud "Ukiyo-e puulõike maailm", 13. IX esitletakse ukiyo-e puulõiketehnikat

  6. 阿蘇観光ホテルと国際リゾート地開発

    OpenAIRE

    砂本,文彦

    2000-01-01

    The aim of this paper is to make clear states of Aso Kanko Hotel and its Development of tourist resort for foreign tourist. O-Aso Kankodo Co. Ltd. was established for development of the area of Aso in 1935. The resort programs they made mainly consisted of roads for drive and a hotel. The hotel called Aso Kanko Hotel was designed by Ryoma Kondo of Kumamoto Prefecture. However its Japanese-European design was indicated by Makoto Den who was the President of Board of Tourist Industry. There wer...

  7. An Integrated Command and Control Architecture Concept for Unmanned Systems in the Year 2030

    Science.gov (United States)

    2010-06-01

    Tan Yean Wee ME5 Tong Kee Leong  Lu  Chin  Leong Chia Boon  Chye Henry Seet ME5 Lo Chee Hun ME5 Gabriel Tham Ho Liang Yoong Raymond Quah Quek Chee Luan Ang...Chia Tan Wei Chieh Chia Boon Chye Yionon Costica Lim Wei Han Eugene Ng Wei Gee Delvin...Gho Lo Chee Hun Tan Chin Wah John Ang Kha Luna Lu Chin Leong Tong Kee Leong

  8. Structuring Pd Nanoparticles on 2H-WS2 Nanosheets Induces Excellent Photocatalytic Activity for Cross-Coupling Reactions under Visible Light.

    Science.gov (United States)

    Raza, Faizan; Yim, DaBin; Park, Jung Hyun; Kim, Hye-In; Jeon, Su-Ji; Kim, Jong-Ho

    2017-10-18

    Effective photocatalysts and their surface engineering are essential for the efficient conversion of solar energy into chemical energy in photocatalyzed organic transformations. Herein, we report an effective approach for structuring Pd nanoparticles (NPs) on exfoliated 2H-WS 2 nanosheets (WS 2 /PdNPs), resulting in hybrids with extraordinary photocatalytic activity in Suzuki reactions under visible light. Pd NPs of different sizes and densities, which can modulate the photocatalytic activity of the as-prepared WS 2 /PdNPs, were effectively structured on the basal plane of 2H-WS 2 nanosheets via a sonic wave-assisted nucleation method without any reductants at room temperature. As the size of Pd NPs on WS 2 /PdNPs increased, their photocatalytic activity in Suzuki reactions at room temperature increased substantially. In addition, it was found that protic organic solvents play a crucial role in activating WS 2 /PdNPs catalysts in photocatalyzed Suzuki reactions, although these solvents are generally considered much less effective than polar aprotic ones in the conventional Suzuki reactions promoted by heterogeneous Pd catalysts. A mechanistic investigation suggested that photogenerated holes are transferred to protic organic solvents, whereas photogenerated electrons are transferred to Pd NPs. This transfer makes the Pd NPs electron-rich and accelerates the rate-determining step, i.e., the oxidative addition of aryl halides under visible light. WS 2 /PdNPs showed the highest turnover frequency (1244 h -1 ) for photocatalyzed Suzuki reactions among previously reported photocatalysts.

  9. Non-enzymatic hydrogen peroxide sensor based on Co 3 O 4 ...

    Indian Academy of Sciences (India)

    Author Affiliations. Guang Sheng Cao1 Lei Wang1 Pengfei Yuan1 Chao Gao1 Xiaojuan Liu1 Tong Li1 Tianmin Li1. Key Laboratory of Enhanced Oil and Gas Recovery of Ministry of Education, Northeast Petroleum University, Daqing 163318, China ...

  10. Non-linearity parameter of binary liquid mixtures at elevated pressures

    Indian Academy of Sciences (India)

    parameter B/A of four binary liquid mixtures using Tong and Dong equation at high pressures and .... in general as regular or ideal as no recognized association takes place between the unlike molecules. In this case ... Using the definition and.

  11. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-04-06

    Apr 6, 2016 ... areas of North America have a low prevalence (<2%). .... statistically significant relationship (p=0.046) between occupation of .... Polish perspectives. Annals of Agricultural and Environmental. Medicine. 2012;19(3):523-527. PubMed | Google Scholar. 5. Tong M, Hwang S. Hepatitis B virus infection in Asian.

  12. 76 FR 58246 - Certain Activated Carbon From the People's Republic of China: Notice of Partial Rescission of...

    Science.gov (United States)

    2011-09-20

    ... Locomotive Coal & Chemicals Co., Ltd.; Datong Tianzhao Activated Carbon Co., Ltd.; DaTong Tri-Star & Power... Activated Carbon; Huzhou Zhonglin Activated Carbon; Inner Mongolia Taixi Coal Chemical Industry Limited... Co., Ltd.; Ningxia Xingsheng Coal and Active Carbon Co., Ltd.; Ningxia Xingsheng Coke & Activated...

  13. Browse Title Index

    African Journals Online (AJOL)

    Items 351 - 400 of 1250 ... Vol 9, No 4 (2012), Aromatherapy as an Adjuvant Treatment in Cancer Care – A Descriptive Systematic Review, Abstract PDF. K Boehm, A Büssing, T Ostermann. Vol 10, No 3 (2013), Arteriovenous fistula failure due to two straight shunts formation at draining vein, Abstract PDF. Y Tong, W Qi, M Sun.

  14. Military and Security Developments Involving the People’s Republic of China 2011

    Science.gov (United States)

    2011-01-01

    cruise missile exhaust system capable of rendering a cruise missile resistant to detection by infrared missiles. In September 2010, Chi Tong Kuok was...for cooperation and competition. Speaking at the Shangri-la Dialogue in June 2010, then-Secretary of Defense Robert Gates asserted that the Defense

  15. Ennekuulmatud loomalaulud / Panda Bear (Noah Lennox) ; interv. Siim Nestor

    Index Scriptorium Estoniae

    Panda Bear (Noah Lennox)

    2006-01-01

    Intervjuu eksperimentaalset popmuusikat viljeleva ameerika ansambli Animal Collective laulja Panda Bear'iga (kontsert 4. juulil Tallinnas Lillepaviljonis). Heliplaatidest: "Spirit They're Gone, Spirit They've Vanished", "Danse Manatee", "Hollindagain", "Campfire Songs", "Here Comes the Indian", "Sung Tongs", "Feels"

  16. http://dx.doi.org/10.4314/ajtcam.v9i2.1

    African Journals Online (AJOL)

    AJTCAM

    UHCC (Chen, 2009; Tong, 2010; Zhang et al., 2006; Zhu and Li, 2006). .... 2006; Yu and Kang, 2009) were identified for further study (726 patients), but without a .... inhibit its transition from G2 phase to M phase in vitro. .... Venook, A. P., Stagg, R. J., Lewis, B. J., Chase, J. L., Ring, E. J., Maroney, T. P., Hohn, D. C., (1990).

  17. Mixed contaminant interactions in soil: Implications for bioavailability ...

    African Journals Online (AJOL)

    user

    Liu H, Zhang D, Li M, Tong L, Feng L (2013b). Competitive adsorption and transport of phthalate esters in the clay layer of JiangHan plain,. China. Chemosphere 92(11):1542-1549. Loffredo E, Senesi N (2006). Fate of anthropogenic organic pollutants in soils with emphasis on adsorption/desorption processes of endocrine.

  18. CD review: Giving voice to hope: music of Liberian refugees | Thorn ...

    African Journals Online (AJOL)

    Title: Giving voice to hope: music of Liberian refugees (2009). One compact disk and booklet. Production supervision by Barry Tonge, Michael Frishkopf, Nancy Hanneman, Ellis Pourbaix and Jennifer Woronuk. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  19. Brain Correlates of the Interaction Between 5-HTTLPR and Psychosocial Stress Mediating Attention Deficit Hyperactivity Disorder Severity

    NARCIS (Netherlands)

    van der Meer, Dennis; Hoekstra, Pieter J.; Zwiers, Marcel; Mennes, Maarten; Schweren, Lizanne J.; Franke, Barbara; Heslenfeld, Dirk J.; Oosterlaan, Jaap; Faraone, Stephen V.; Buitelaar, Jan K.; Hartman, Catharina A.

    Objective: The serotonin transporter 5-HTTLPR genotype has been found to moderate the effect of stress on severity of attention deficit hyperactivity disorder (ADHD), with stronger effects of stress in carriers of the short allele than in individuals homozygous for the tong allele. The underlying

  20. 16 CFR 1632.4 - Mattress test procedure.

    Science.gov (United States)

    2010-01-01

    ... position at a reasonable height for making observations. (ii) If thin flexible mattresses or mattress pads... relative humidity measuring instrument, a thin rod, straight pins, a knife or scissors, and tongs are... (from water bottle), cut around the burning material with a knife or scissors and pull the material out...

  1. HEP meets ML award talk : XGBoost

    CERN Multimedia

    CERN. Geneva; CHEN, Tianqi

    2015-01-01

    Tianqi Chen and Tong He (team crowwork) have provided very early in the challenge to all participants XGBoost (for eXtreme Gradient Boosted). It is a parallelised software to train boost decision trees, which has been effectively used by many participants to the challenge. For this, they have won the "HEP meets ML" award which is the invitation to CERN happening today.

  2. Dynamics of water transport and storage in conifers studied with deuterium and heat tracing techniques.

    Science.gov (United States)

    F.C. Meinzer; J.R. Brooks; J.-C. Domec; B.L. Gartner; J.M. Warren; D.R. Woodruff; K. Bible; D.C. Shaw

    2006-01-01

    The volume and complexity of their vascular systems make the dynamics of tong-distance water transport in large trees difficult to study. We used heat and deuterated water (D20) as tracers to characterize whole-tree water transport and storage properties in individual trees belonging to the coniferous species Pseudotsuga menziesii...

  3. Effects of Practical Life Materials on Kindergartners' Fine Motor Skills.

    Science.gov (United States)

    Rule, Audrey C.; Stewart, Roger A.

    2002-01-01

    A pretest-posttest control group design was used to measure the effect of practical life materials (e.g., tweezers, tongs, spoons) on kindergarten children's fine motor skill development. Experimental and control group teachers reported equal amounts of fine motor activity in their classrooms; however, significant interaction effects were found…

  4. What Really Happened in Northern Ireland’s Counterinsurgency: Revision and Revelation

    Science.gov (United States)

    2008-10-01

    account requires reaching back into Ireland’s misty past and its relations with the larger island to its east. England’s first large-scale invasion of... Armour Press, 1985), page 228. 53. Jonathan Tonge, Northern Ireland (Cambridge, United Kingdom: Polity Press, 2006), page 71. 54. Dewar, British Army

  5. Untitled

    African Journals Online (AJOL)

    These concerns in- clude the environmental impact of animal pollution with solid and liquid wastes, as well as the effects of dog Overpopulation and Stray animals on community health. A high *dog-to-man'' contact rate has been recorded in parts of the Country, particulady in urban areas (Tong, 1992; Awah-Ndukum, 2003).

  6. Sensing of polymeric sensor-based rhodamine B derivative for metal ...

    Indian Academy of Sciences (India)

    TONG-MOU GENG1 XIE WANG1 FENG ZHU1 HUI JIANG1 YU WANG2. Collaborative Innovation Center for Petrochemical New Materials, Anhui Key Laboratory of Functional Coordination Compounds, School of Chemistry and Chemical Engineering, Anqing Normal University, Anqing 246011, People's Republic of China ...

  7. Charging machine for a fast production reactor

    International Nuclear Information System (INIS)

    Artem'ev, L.N.; Kurilkin, V.V.

    1971-01-01

    Charging machine for a fast production reactor is described. The machine contains charging mechanism, mechanism for positioning fresh fuel and spent fuel assemtlies, storage drums with sockets for control rod assemtlies and collet tongs for control rods. Recharging is conducted by means of ramp channel

  8. 76 FR 67178 - Riverbank Hydro No. 15 LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-10-31

    ... Corps. Applicant Contact: Mr. Kuo-Bao Tong, Riverbank Power Corporation, Royal Bank Plaza, South Tower, P.O. Box 166, 200 Bay Street, Suite 3230, Toronto, ON, Canada M5J2J4. (416) 861-0092 x 154. FERC...

  9. Interactions of barley alpha-amylase isozymes with Ca2+, substrates and proteinaceous inhibitors

    DEFF Research Database (Denmark)

    Abou Hachem, Maher; Bozonnet, Sophie; Willemoes, Martin

    2006-01-01

    discovered 'sugar tongs' site in domain C of AMY1 is thus critical for binding to starch granules. Furthermore, mutations of binding sites mostly reduced the degree of multiple attack in amylose hydrolysis. AMY1 has higher substrate affinity than AMY2, but isozyme chimeras with AMY2 domain C and other...

  10. Limit law of the iterated logarithm for B-valued trimmed sums

    Indian Academy of Sciences (India)

    Limit law of the iterated logarithm for B-valued trimmed sums. KE-ANG FU1, YUYANG QIU1,∗ and YELING TONG2. 1School of Statistics and Mathematics, Zhejiang Gongshang University,. Hangzhou 310018, China. 2Zhejiang Institute of Traditional Chinese Medicine, Hangzhou 310028, China. *Corresponding author.

  11. Comparison of genetic detection efficiency of different markers ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-06-03

    Jun 3, 2009 ... Chinese native sheep populations, Hu sheep, Tong sheep, Small-tailed Han sheep and Tan sheep were used to study the efficiency of genetic markers. The genetic markers used in this study include morphological and ecological indices, blood protein enzyme, microsatellite DNA and the combination of.

  12. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 150 of 1250 ... Vol 10, No 6 (2013), A study on the anticancer activity of ethanol extract of ... S Han, X Lv, Y Wang, H Gong, C Zhang, A Tong, N Yan ... YJ Wanga, Y Zhenga, GF Zhang, JP Zhanga, CX Wua, SQ Zhang, HL Ouyang, ...

  13. Genetic variation of indigenous chicken breeds in China and a ...

    African Journals Online (AJOL)

    huis

    Genetic variation of indigenous chicken breeds in China and a Recessive White breed using AFLP fingerprinting. Yushi Gao. 1,2#. , Yunjie Tu. 1,2. , Haibin Tong. 1. , Kehua Wang. 1. , Xiujun Tang. 1 and Kuanwei Chen. 1. 1 Institute of Poultry, Academy of Agricultural Sciences in China, Yangzhou, 225003, Jiangsu, China.

  14. Effect of Chinese medical herbs-Huiru Yizeng Yihao on ...

    African Journals Online (AJOL)

    The model rat of HMG was prepared by injecting estradiol in the thigh muscle of the rats and progesterone consecutively, while the tails of rats were clipped with tongs. Rats were treated with either NO.1 HRYZ or positive control drugs for four weeks. The concentrations of sex hormone in rat serum were examined using ...

  15. Characteristics of molecular changes in lespedeza plants after ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-15

    Sep 15, 2009 ... Scientia Agricultura Sinica, 31(6):. 1-5. Ren WB, Han JG, Zhang YW, Tong YC, Wang ZP (2006). A test report of space mutagenesis of Lespedeza bicolor. Acta Agrestia Sinica, 14: 112-115. Vaulina EN, Kostina LN (1975). Modifying effect of dynamic space flight factors on radiation damage of air-dry seeds ...

  16. Sharp Bounds for Symmetric and Asymmetric Diophantine Approximation

    Institute of Scientific and Technical Information of China (English)

    Cornelis KRAAIKAMP; Ionica SMEETS

    2011-01-01

    In 2004,Tong found bounds for the approximation quality of a regular continued fraction convergent to a rational number,expressed in bounds for both the previous and next approximation.The authors sharpen his results with a geometric method and give both sharp upper and lower bounds.The asymptotic frequencies that these bounds occur are also calculated.

  17. Human Bites of the Face with Tissue Losses in Cosmopolitan ...

    African Journals Online (AJOL)

    Dr. Milaki Asuku

    A retrospective series of thirty-six cases of human bites to the face with tissue losses requiring reconstruction ..... bite wounds when compared to other forms of trauma in our regional ... References. 1. Liston PN, Tong DC, Firth NA, Kieser JA.

  18. University Rankings: The Web Ranking

    Science.gov (United States)

    Aguillo, Isidro F.

    2012-01-01

    The publication in 2003 of the Ranking of Universities by Jiao Tong University of Shanghai has revolutionized not only academic studies on Higher Education, but has also had an important impact on the national policies and the individual strategies of the sector. The work gathers the main characteristics of this and other global university…

  19. Academic Ranking of World Universities and the Performance of East Asian Universities. RIHE International Seminar Reports. No. 24

    Science.gov (United States)

    Liu, Nian Cai

    2016-01-01

    The first multi-indicator ranking of world universities, "Academic Ranking of World Universities (ARWU)", was published by the Institute of Higher Education of Shanghai Jiao Tong University in June 2003. Although the initial purpose of ARWU was to find the global standing of top Chinese universities, it has been attracting world-wide…

  20. Humidity is an ambient parameter to development of Zika virus

    African Journals Online (AJOL)

    a tropical climate and rich natural resources and biodiver- sity7. ... Ethical approval. This article does not contain ... African Health Sciences Vol 17 Issue 2, June, 2017. 597 ... en K, Tong S. Climate change and dengue: a critical and systematic ...

  1. Pop / Mart Kuldkepp

    Index Scriptorium Estoniae

    Kuldkepp, Mart

    2008-01-01

    Heliplaatidest: James "Hey Ma", Kelder "Vikerkaar ja latimeeria", David Torn "Lars and the Real Girl. Music from the motion picture", Tanel Ruben "Kogutud rikkus", Neon Neon "Stainless Style", 3 Doors Down "3 Doors Down", Winston Tong "In a Manner Of Speaking (Best Of)", Witch "Paralyzed"

  2. Beschrijving Nederlandse visserij in de Noordzee, EEZ en het Nederlandse kustgebied ten behoeve van Natuurbalans 2003

    NARCIS (Netherlands)

    Verver, S.W.; Grift, R.E.; Quirijns, F.J.

    2003-01-01

    De Nederlandse demersale visserij richt zich met name op schol, tong, kabeljauw en wijting en heeft als belangrijke bijvangstsoorten tarbot en griet. Het aandeel van de Nederlandse visserij in de totale aanlandingen van de Noordzee bedraagt voor schol gemiddeld 52% op jaarbasis. Nederland heeft een

  3. Examining Construct Congruence for Psychometric Tests: A Note on an Extension to Binary Items and Nesting Effects

    Science.gov (United States)

    Raykov, Tenko; Marcoulides, George A.; Dimitrov, Dimiter M.; Li, Tatyana

    2018-01-01

    This article extends the procedure outlined in the article by Raykov, Marcoulides, and Tong for testing congruence of latent constructs to the setting of binary items and clustering effects. In this widely used setting in contemporary educational and psychological research, the method can be used to examine if two or more homogeneous…

  4. Genetic Variability in Soybean (Glycine max L.) for Low Soil ...

    African Journals Online (AJOL)

    Abush Tesfaye

    worldwide importance as food and market crop. This is mainly because of its high ... The application of inorganic P fertilizers is one of the possibilities for addressing the problem of low P availability. However ...... Soybean Research Conference held in Foz do Iguassu, Brazil, 1-5 March, 2004. Tong, X.J., X. Yan, Y.G. Lu, ...

  5. Nearly 30% of Centrally-administered SOEs Suffer Losses from Overseas Investment

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>At the China Mining Congress, Tong Junhu, general manager of the Overseas Development Department of China National Gold Group Corp., told a reporter with Economic Information Daily that overseas M&A entailed a lot of uncertainties and huge risks, and enterprises should not act rashly because once they make payment, it would be difficult to control.

  6. Proteomic identification of CIB1 as a potential diagnostic factor in ...

    Indian Academy of Sciences (India)

    Proteomic identification of CIB1 as a potential diagnostic factor in hepatocellular carcinoma. Tong Junrong Zhou Huancheng H E Feng Gao Yi Yang Xiaoqin Luo Zhengmao Zhang Hong Zeng Jianying Wang Yin Huang Yuanhang Zhang Jianlin Sun Longhua He Guolin. Articles Volume 36 Issue 4 September 2011 pp 659- ...

  7. Should pregnant urban South African women be screened for ...

    African Journals Online (AJOL)

    Yet despite this hypothetical sce- nario, in a study of 2 364 urban-born black children .... Srevens CE, Toy PT, Tong Mj, el al. Perinatal hepatitis B virus ... randomized double-blind placebo-controlled and comparative trial. Pedialries 1985; 76: ...

  8. Fabrication and characterization of PDLLA/pyrite composite bone ...

    Indian Academy of Sciences (India)

    Keywords. Polylactic acid; Chinese herbal medicine; pyrite; scaffold; bone regeneration; cell culture. ... Pyrite (FeS2, named as Zi-Ran-Tong in Chinese medicine), as a traditional Chinesemedicine, has been used in the Chinese population to treat bone diseases and to promote bone healing. The mechanical properties of ...

  9. Effect of hypoxia-inducible factor 1-alpha (HIF-1α) on proliferation ...

    African Journals Online (AJOL)

    Jane

    2011-07-25

    Jul 25, 2011 ... Full Length Research Paper. Effect of hypoxia-inducible factor 1-alpha ... 1Department of Neurosurgery, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025,. China. 2Department of Neurosurgery, Chaoyang Hospital, Huainan, Anhui, China. 3Department of Neurosurgery ...

  10. Needs and Concerns of Male Combat Veterans with Mild Traumatic Brain Injury

    Science.gov (United States)

    2013-01-01

    is bothering me . . . . I bought an old house and I’ve been remodeling it. And I found some old dressers from an old house, I’ve been refin- ishing...EW, Tong EC, Yip SC, Lui WF, Lam CS. Health services needs and quality of life assessment of individuals with brain injuries: a pilot cross -sectional

  11. Cervical spine cord injury in pregnancy. Conservative management ...

    African Journals Online (AJOL)

    Study design A prospective study of 3 patients with incomplete cervical spinal cord injury in the 3rd trimester of pregnancy. Objectives To determine the effect of spinal cord injury and treatment with Gardner-Wells\\' Tong traction on pregnancy, labour and parturition; and ascertain the effectiveness and safety of this ...

  12. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yang Zhao1 Haiqing Tong1 Ronghao Cai1 Xiaojian Peng1 Xiaoyu Li1 Defang Gan2 Suwen Zhu1. Key Laboratory of Crop Biology of Anhui Province, School of Life Sciences, Anhui Agricultural University, Hefei 230036, People's Republic of China; School of Horticulture, Anhui Agricultural University, Hefei 230036, People's ...

  13. 49 CFR 178.57 - Specification 4L welded insulated cylinders.

    Science.gov (United States)

    2010-10-01

    ... lot of cylinders. The test piece must be welded by the same welding procedure as used on the... conform to requirements of ASTM Standard E 23. The test piece, as well as the handling tongs, must be... than six seconds. (vii) The impact properties of each set of impact specimens may not be less than the...

  14. Back of the Envelope Reasoning for Robust Quantitative Problem Solving

    Science.gov (United States)

    2007-12-31

    limited numeric vocabulary, for example, the Pirahã tribe in Amazonia [Gordon, 2004] and Munduruku [Pica et al., 2004], an Amazonian language... investigation of category structure: 1. Level of categorization: Rosch [1978] identifies three levels of categorization: subordinate, basic-level...Using Common Sense Knowledge to Overcome Brittleness and Knowledge Acquisition Bottlenecks. AI Magazine . Lenhart K. Schubert and Matthew Tong

  15. Een stad, drie rooikoppe, sewe dae. Adeline en Lili Radloff. Pretoria ...

    African Journals Online (AJOL)

    'n Prysenswaardige eienskap van Een stad, drie rooikoppe, sewe dae, is die sonder-hand- skoene gebruik van humor. In hierdie opsig kan die roman beskryf word as 'n misdaad- komedie wat in 'n vernuwing van Marita van der Vyver-styl gelaai is met ironiese, skerp, sarkastiese, droë, byderwetse, tong-in-die-kies humor.

  16. An efficient somatic embryogenesis based plant regeneration from ...

    African Journals Online (AJOL)

    ajl yemi

    2010-03-05

    Mar 5, 2010 ... Fang Yuan, Quan Wang, Qifang Pan, Guofeng Wang, Jingya Zhao, Yuesheng Tian and. Kexuan Tang*. Plant Biotechnology Research Center, School of Agriculture and Biology, Fudan-SJTU-Nottingham Plant Biotechnology. R&D Center, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.

  17. Evaluation of essential oil composition and DNA diversity of mint ...

    African Journals Online (AJOL)

    use

    2011-11-23

    Nov 23, 2011 ... Full Length Research Paper. Evaluation of essential oil composition and DNA diversity of mint resources from China. Chen Xiao Hua, G. R. Wang and Yao Lei*. Aromatic Plant R&D Centre, School of Agriculture and Biology, Shanghai Jiao Tong University Shanghai 200240, China. Accepted 19 September ...

  18. {open_quote}Nintendo Rig{close_quote} lets two men do work of three on traditional servicing rig

    Energy Technology Data Exchange (ETDEWEB)

    Rintoul, B.

    1996-01-01

    New well servicing rig saves costs and increases safety by using a robot derrickman. The rigs is called the Nintendo Rig, taking the name from the joystick that controls the robot on the racking board 25 feet above the ground. An automated tong/slip package permanently mounted on the front of the rig handles pipe and rods on the ground.

  19. From the Beauty of Genomic Landscapes to the Strength of Transcriptional Mechanisms.

    Science.gov (United States)

    Natoli, Gioacchino

    2016-03-24

    Genomic analyses are commonly used to infer trends and broad rules underlying transcriptional control. The innovative approach by Tong et al. to interrogate genomic datasets allows extracting mechanistic information on the specific regulation of individual genes. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Securing the Workforce

    DEFF Research Database (Denmark)

    Clausen, Lisbeth; Kruuse, Mikkel

    2015-01-01

    . In this case, we present the story of the general manager Mieko Suzuki, who worked in the Japanese subsidiary of an American multinational information technology company - X-tech. In 2012, Mieko Suzuki was head-hunted to create a more inclusive work environment in the Japanese subsidiary. She knew the Japanese.......thecasecentre.org/CBSfreecases for more information on the collection). This case can be downloaded by educators as a clean pdf by viewing the on-line inspection copy. Access is unlimited and you may print as many copies as you wish for use with your students....

  1. HandaPhos

    DEFF Research Database (Denmark)

    Handa, Sachin; Andersson, Martin Peter; Gallou, Fabrice

    2016-01-01

    The new monophosphine ligand HandaPhos has been identified such that when complexed in a 1:1 ratio with Pd(OAc)2, enables Pd-catalyzed cross-couplings to be run using ≤1000 ppm of this pre-catalyst. Applications to Suzuki-Miyaura reactions involving highly funtionalized reaction partners are demo......The new monophosphine ligand HandaPhos has been identified such that when complexed in a 1:1 ratio with Pd(OAc)2, enables Pd-catalyzed cross-couplings to be run using ≤1000 ppm of this pre-catalyst. Applications to Suzuki-Miyaura reactions involving highly funtionalized reaction partners...

  2. Examination of a pre-exercise, high energy supplement on exercise performance

    Directory of Open Access Journals (Sweden)

    Tranchina Christopher P

    2009-01-01

    Full Text Available Abstract Background The purpose of this study was to examine the effect of a pre-exercise high energy drink on reaction time and anaerobic power in competitive strength/power athletes. In addition, the effect of the pre-exercise drink on subjective feelings of energy, fatigue, alertness and focus was also explored. Methods Twelve male strength/power athletes (21.1 ± 1.3 y; 179.8 ± 7.1 cm; 88.6 ± 12.1 kg; 17.6 ± 3.3% body fat underwent two testing sessions administered in a randomized and double-blind fashion. During each session, subjects reported to the Human Performance Laboratory and were provided with either 120 ml of a high energy drink (SUP, commercially marketed as Redline Extreme® or 120 ml of a placebo (PL that was similar in taste and appearance but contained no active ingredients. Following consumption of the supplement or placebo subjects rested quietly for 10-minutes prior to completing a survey and commencing exercise. The survey consisted of 4 questions asking each subject to describe their feelings of energy, fatigue, alertness and focus for that moment. Following the completion of the questionnaire subjects performed a 2-minute quickness and reaction test on the Makoto testing device (Makoto USA, Centennial CO and a 20-second Wingate Anaerobic Power test. Following a 10-minute rest subjects repeated the testing sequence and after a similar rest period a third and final testing sequence was performed. The Makoto testing device consisted of subjects reacting to both a visual and auditory stimulus and striking one out of 30 potential targets on three towers. Results Significant difference in reaction performance was seen between SUP and PL in both average number of targets struck (55.8 ± 7.4 versus 51.9 ± 7.4, respectively and percent of targets struck (71.9 ± 10.5% versus 66.8 ± 10.9%, respectively. No significant differences between trials were seen in any anaerobic power measure. Subjective feelings of energy (3.5 ± 0

  3. Active and passive faults detection by using the PageRank algorithm

    Science.gov (United States)

    Darooneh, Amir H.; Lotfi, Nastaran

    2014-08-01

    Here we try to find active and passive places for earthquakes in the geographical region of Iran. The approach of Abe and Suzuki is adopted for modeling the seismic history of Iran by a complex directed network. By using the PageRank algorithm, we assign to any places in the region an activity index. Then, we determine the most active and passive places.

  4. Palladiové nanočástice v katalýze spojovacích reakcí

    Czech Academy of Sciences Publication Activity Database

    Demel, Jan; Čejka, Jiří; Štěpnička, P.

    2009-01-01

    Roč. 103, č. 2 (2009), s. 145-153 ISSN 0009-2770 Institutional research plan: CEZ:AV0Z40400503 Keywords : palladium * palladium nanoparticles * Heck reaction * Suzuki reaction Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.717, year: 2009

  5. Erratum: Google Earth as Geoscience Data Browser Project: Development of a Tool to Convert JAMSTEC Research Vessel Navigation Data to KML [Data Science Journal, Volume 8, 30 March 2009. S85-S91

    Directory of Open Access Journals (Sweden)

    Y Yamagishi

    2009-07-01

    Full Text Available The following PDF indicates errata for the original article entitled "Google Earth as Geoscience Data Browser Project: Development of a Tool to Convert JAMSTEC Research Vessel Navigation Data to KML" by Y Yamagishi, H Nagao, K Suzuki, H Tamura, T Hatakeyama, H Yanaka and S Tsuboi.

  6. An algorithm to find all palindromic sequences in proteins

    Indian Academy of Sciences (India)

    2013-01-20

    Jan 20, 2013 ... 1976; Karrer and Gall 1976; Vogt and Braun 1976) and (iii) in the formation of hairpin loops in the newly transcribed RNA. Palindromic sequences are observed in various classes of proteins like histones (Cheng et al. 1989), prion proteins (Sulkowski 1992; Kazim 1993),. DNA-binding proteins (Suzuki 1992; ...

  7. マーケティングのパイオニア : 森永太一郎と鈴木三郎助

    OpenAIRE

    森田, 克徳

    1998-01-01

    This paper attempts to clarify the business activities of Taichiro Morinaga and Saburosuke Suzuki, especially of marketing. The former is the founder of Morinagaseika which was inagurated in 1899, and the latter is the founder of Ajinomoto established in 1908. Morinagaseika is a first-mover in the confectionery industory in Japan and Ajinomoto in the seasoning industory too.

  8. Dynamic intervention: pathogen disarmament of mitochondrial-based immune surveillance.

    Science.gov (United States)

    Holland, Robin L; Blanke, Steven R

    2014-11-12

    In this issue of Cell Host & Microbe, Suzuki et al. (2014) describe a Vibrio cholerae Type-III-secreted effector that targets mitochondrial dynamics to dampen host innate immune signaling. This suggests that mammalian hosts possess surveillance mechanisms to monitor pathogen-mediated alterations in the integrity of normal cellular processes and organelles. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Author Details

    African Journals Online (AJOL)

    Suzuki, T. Vol 15, No 4 (2009) - Articles General anaesthesia with and without intubation for patients with Cornelia de Lange syndrome. Abstract PDF · Vol 15, No 5 (2009) - Articles Anaesthesia for a morbidly obese patient with schizophrenia and intellectual disability. Abstract PDF. ISSN: 2220-1173. AJOL African Journals ...

  10. Southern African Journal of Anaesthesia and Analgesia - Vol 15, No ...

    African Journals Online (AJOL)

    Anaesthesia for a morbidly obese patient with schizophrenia and intellectual disability · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Y Asahi, Y Kawai, M Sugimoto, T Suzuki, S Omichi, J Kotani, 32-33. http://dx.doi.org/10.1080/22201173.2009.10872621 ...

  11. Aging, rejuvenation, and memory effects in short-range Ising spin glass: Cu_0.5Co_0.5Cl_2-FeCl3 GBIC

    Science.gov (United States)

    Suzuki, M.; Suzuki, I. S.

    2004-03-01

    Cu_0.5Co_0.5Cl_2-FeCl3 GBIC undergoes a spin glass (SG) transition at Tg (= 3.92 ± 0.11 K). The system shows a dynamic behavior that has some similarities and some significant differences compared to a 3D Ising SG.^1 Here we report on non-equilibrium aging dynamics which has been studied using zero-field cooled (ZFC) magnetization and low frequency AC magnetic susceptibility.^2 The time dependence of the relaxation rate S(t) = (1/H)dM_ZFC/dln t for the ZFC magnetization after the ZFC aging protocol, shows a peak at a characteristic time t_cr near a wait time t_w, corresponding to a crossover from quasi equilibrium dynamics to non-equilibrium. The time t_cr strongly depends on t_w, temperature, magnetic field, and the temperature shift. The rejuvenation effect is observed in both i^' and i^'' under the T-shift and H-shift procedures. The memory of the specific spin configurations imprinted during the ZFC aging protocol can be recalled when the system is re-heated at a constant heating rate. The aging, rejuvenation, and memory effects are discussed in terms of the scaling concepts derived from numerical studies on 3D Edwards-Anderson spin glass model. 1. I.S. Suzuki and M. Suzuki, Phys. Rev. B 68, 094424 (2003) 2. M. Suzuki and I.S. Suzuki, cond-mat/0308285

  12. Application of DYNA3D in large scale crashworthiness calculations

    International Nuclear Information System (INIS)

    Benson, D.J.; Hallquist, J.O.; Igarashi, M.; Shimomaki, K.; Mizuno, M.

    1986-01-01

    This paper presents an example of an automobile crashworthiness calculation. Based on our experiences with the example calculation, we make recommendations to those interested in performing crashworthiness calculations. The example presented in this paper was supplied by Suzuki Motor Co., Ltd., and provided a significant shakedown for the new large deformation shell capability of the DYNA3D code. 15 refs., 3 figs

  13. PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p

    NARCIS (Netherlands)

    Okumoto, K.; Shimozawa, N.; Kawai, A.; Tamura, S.; Tsukamoto, T.; Osumi, T.; Moser, H.; Wanders, R. J.; Suzuki, Y.; Kondo, N.; Fujiki, Y.

    1998-01-01

    Rat PEX12 cDNA was isolated by functional complementation of peroxisome deficiency of a mutant CHO cell line, ZP109 (K. Okumoto, A. Bogaki, K. Tateishi, T. Tsukamoto, T. Osumi, N. Shimozawa, Y. Suzuki, T. Orii, and Y. Fujiki, Exp. Cell Res. 233:11-20, 1997), using a transient transfection assay and

  14. Convergence properties of the effective interaction

    International Nuclear Information System (INIS)

    Ellis, P.J.; Engeland, T.; Hjorth-Jensen, M.; Holt, A.; Osnes, E.

    1994-01-01

    The convergence properties of two perturbative schemes to sum the so-called folded diagrams are critically reviewed in this work, with an emphasis on the intruder state problem. The methods we study are the approaches of Kuo and co-workers and Lee and Suzuki. The suitability of the two schemes for shell-model calculations is discussed. ((orig.))

  15. Recent Applications of Polymer Supported Organometallic Catalysts in Organic Synthesis

    Directory of Open Access Journals (Sweden)

    Nina Kann

    2010-09-01

    Full Text Available Recent developments concerning the application of polymer supported organometallic reagents in solid phase synthesis are reviewed, with a special focus on methodology for carbon-carbon formation. Examples of reactions that are covered include the classical Suzuki, Sonogashira and Heck coupings, but also aryl amination, epoxide opening, rearrangements, metathesis and cyclopropanation. Applications in the field of asymmetric synthesis are also discussed.

  16. Calorimetric studies of non-isothermal crystallization in amorphous

    Indian Academy of Sciences (India)

    Administrator

    the peak crystallization temperature. Amorphous alloys of Cu–Ti system are of special interest (Koster et al 1995) due to the fact that Cu–Ti is a congruently melting compound, which should allow static under-cooling experiments. Several works ... tion when mixed with another metal or rare earth metals. (Suzuki et al 2003).

  17. Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives.

    Science.gov (United States)

    Kaffy, Julia; Pontikis, Renée; Florent, Jean-Claude; Monneret, Claude

    2005-07-21

    Stereospecific syntheses of the Z-E and E-Z vinylogues of combretastatin A-4, and two B-ring related analogues, were achieved through a Suzuki-Miyaura coupling. As compared to CA4, the derivative with a phenyl moiety has shown increased potency in its ability to inhibit tubulin polymerisation.

  18. PhysicsWeb

    CERN Multimedia

    2008-01-01

    KEK's Atsuto Suzuki has something to smile about The particle physics community started 2008 with a bad case of the January blues, thanks to major budget cuts announced by the US and UK just before Christmas. But some comfort may be taken from very positive plans for the future unveiled by the Japanese high-energy physics laboratory, KEK.

  19. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    The bisphosphomide-based pincer complex [PdBr{2,6-{Ph2PC(O)}2(C6H3)}] (2) has shown very high catalytic activity in Suzuki-Miyaura cross coupling reaction under microwave irradiation for a variety of aryl bromides and aryl boronic acids. The complex showed the same efficiency for gram scale reactions.

  20. Nickel(II) complexes containing ONS donor ligands: Synthesis ...

    Indian Academy of Sciences (India)

    MS received 23 July 2014; revised 28 November 2014; accepted 28 November 2014 ... Nickel(II) complexes; X-ray structure; Kumada-Corriu reaction; Suzuki reaction; ...... 29 75. 37. Kovala-Demertzi D, Demertzis M A, Miller J R,. Papadopoulou C ... Biochem. 86 555. 38. Bellamy L J 1985 In The Infrared Spectra of Complex.

  1. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Supported Pd nanoparticles on acetyl acetone modified silica gel was prepared and its catalytic application in the Suzuki-Miyaura reaction of various aryl halides with phenylboronic acid was investigated. The reaction was carried out in water as solvent under green conditions in the presence of NaHCO3 as the base.

  2. Preliminary studies of the antibacterial activities of processed ...

    African Journals Online (AJOL)

    AJB SERVER

    2006-10-06

    Oct 6, 2006 ... Toda M, Okubo S, Ikigai H, Suzuki T, Shimamura T (1991). The protective activity of the tea against infection by Vibrio cholerae J. Appl. Bacterial 70: 109 – 112. Toda M, Okubo S, Hiyoshi R, Shimamura T(1989) Antibacterial and bactericidal activities of Japanese green tea. Jpn. J. Bacteriol 44(4):. 669-672.

  3. Convergence properties of the effective interaction

    International Nuclear Information System (INIS)

    Ellis, P.J.; Engeland, T.; Hjorth-Jensen, M.; Holt, A.; Osnes, E.

    1993-10-01

    The convergence properties of two perturbative schemes to sum the so called folded diagrams are critically reviewed with an emphasis on the intruder state problem. The methods studied are the approaches of Kuo and co-workers and Lee and Suzuki. The suitability of the two schemes for shell-model calculations is discussed. 11 refs., 3 figs., 1 tab

  4. Fulltext PDF

    Indian Academy of Sciences (India)

    Konstantin Novoselov, University of Manchester, Manchester, United Kingdom. Chemistry. “for palladium-catalyzed cross couplings in organic synthesis” to. Richard F Heck, University of Delaware, USA;. Ei-ichi Negishi, Purdue University, West Lafayette, IN, USA;. Akira Suzuki, Hokkaido University, Sapporo, Japan.

  5. Kenad ja kõrged / Aimo Niemi, Pekka Aromaa, Olli Laitinen ja Jari Pitkäjärvi

    Index Scriptorium Estoniae

    2016-01-01

    Linnamaasturite võrdlus: Fiat 500X 1,4 Multiair Popstar, Honda HR-V 1,5 i-VTEC Elegance, Mazda CX-3 2,0 Skyactiv-G Premium Plus, Opel Mokka 1,4 Turbo ECOTEC Start/Stop, Ssangyong Tivoli 1,6i 2WD Quartz, Suzuki Vitara 1,6 VVT GLX

  6. Case report

    African Journals Online (AJOL)

    abp

    8 mai 2014 ... Fonte D, Águas L, Alves L, Sotto-mayor C, Pinto G. Carcinoma epitelialmioepitelial da parotida. Acta Med Port. 2011; 24(S3):. 675-680. PubMed | Google Scholar. 4. Kumagai M, Suzuki H, Matsuura K, Takahashia E, et al. Epithelial_myoepithelial carcinoma of the parotid gland. Auris. Nasus Larynx. 2003 ...

  7. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... 4' -methylenedioxyphenyl)-5,6,7-trimethoxyisoflavone] derivatives, structurally similar to glaziovianin A, a known cytotoxic substance, has been described. The key steps in the synthesis are site selective bromination reaction followed by Suzuki coupling reaction in very good yield. The structural assignment of the bromo ...

  8. umbilical cord parameters in ilorin: correlates and foetal outcome

    African Journals Online (AJOL)

    2014-08-08

    Aug 8, 2014 ... The foetal outcomes were assessed by APGAR scores, birth weight, admission to neonatal intensive ... between the umbilical cord parameters and perinatal events such as Apgar scores and birth weight. .... Suzuki S, Fuse Y. Length of the Umbilical Cord and. Perinatal Outcomes in Japanese Singleton ...

  9. Synthesis and biological evaluation of flexible and conformationally constrained LpxC inhibitors

    DEFF Research Database (Denmark)

    Löppenberg, Marius; Müller, Hannes; Pulina, Carla

    2013-01-01

    , conformationally constrained C-glycosidic as well as open chained hydroxamic acids with a defined stereochemistry were prepared. Diversity was introduced by performing C–C coupling reactions like the Sonogashira and Suzuki cross-coupling reactions. The biological evaluation of the synthesized compounds revealed...

  10. Small band gap copolymers based on furan and diketopyrrolopyrrole for field-effect transistors and photovoltaic cells

    NARCIS (Netherlands)

    Bijleveld, Johan C.; Karsten, Bram P.; Mathijssen, Simon G.J.; Wienk, Martijn M.; Leeuw, Dago M. de; Janssen, René A.J.

    2011-01-01

    Four small band gap semiconducting copolymers based on electron deficient diketopyrrolopyrrole alternating with electron rich trimers containing furan and benzene or thiophene have been synthesized via Suzuki polymerization. The polymers have optical band gaps between 1.4 and 1.6 eV, optimized for

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ), lime (CaO), corundum (Al2O3) and spinel (MgAl2O4) determined experimentally by Fiquet et al (1999) from 300K up to 3000K. The thermal equation of state due to Suzuki et al (1979) and Shanker et al (1997) are used to study the ...

  12. Syntheses of the hexahydroindene cores of indanomycin and stawamycin by combinations of iridium-catalyzed asymmetric allylic alkylations and intramolecular Diels-Alder reactions.

    Science.gov (United States)

    Gärtner, Martin; Satyanarayana, Gedu; Förster, Sebastian; Helmchen, Günter

    2013-01-02

    Short and concise syntheses of the hexahydroindene cores of the antibiotics indanomycin (X-14547 A) and stawamycin are presented. Key methods used are an asymmetric iridium-catalyzed allylic alkylation, a modified Julia olefination, a Suzuki-Miyaura coupling, and an intramolecular Diels-Alder reaction. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Synthesis and conformational studies of a series of 5,17-bis-aryl-25,26,27,28-tetrapropoxycalix[4]arenes: The influence of π-π interactions on the molecular structure

    DEFF Research Database (Denmark)

    Larsen, M.; Krebs, Frederik C; Harrit, N.

    1999-01-01

    Four 5,17-bis-aryl-25,26,27,28-tetrapropoxycalix[4]arenes were prepared via Negishi, Suzuki and Ullman type couplings [aryl = phenyl (1), 3-bromophenyl (2), 1-naphthyl (3) and carbazol-9-yl (4)]. The influence of the aryl groups on the structure was studied by X-ray crystallography, NMR, electron...

  14. A novel synthesis of hemispherands

    NARCIS (Netherlands)

    Ostaszewski, Ryszard; Verboom, Willem; Reinhoudt, David

    1992-01-01

    A novel, flexible synthesis of hemispherands {2,5,8-trioxa[9](3,3″) m-terphenylophanes 5a-d} with different central aromatic groups is described. The key step comprises the introduction of the central aromatic ring in the last step of the synthesis via a Suzuki cross-coupling reaction using

  15. Singing and Moving: Teaching Strategies for Audiation in Children

    Science.gov (United States)

    Garner, Allison Maerker

    2009-01-01

    Listening skills are fundamental in the author's approach to teaching music to children. As a Suzuki instructor, the author is always looking for ways to help students listen more effectively. This article sets forth ways listening can be fostered, both in private instrumental study and in general music preschool and elementary classrooms. The…

  16. Evidence of High-Spin Ru and Universal Magnetic Anisotropy in SrRuO(3) Thin Films

    Science.gov (United States)

    2012-04-17

    films also exhibit significantly decreased mobility that we believe to be associated with a higher incidence of defects and increased mosaic spread...VAILIONIS, AND SUZUKI PHYSICAL REVIEW B 85, 134429 (2012) 12D. Toyota , I. Ohkubo, H. Kumigashira, M. Oshima, T. Ohnishi, M. Lippmaa, M. Takizawa, A

  17. Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5-and 6-substituted 4-amino- or 4-alkylpyrimido [4,5-b]indole ribonucleosides

    Czech Academy of Sciences Publication Activity Database

    Tichý, Michal; Pohl, Radek; Tloušťová, Eva; Weber, Jan; Bahador, G.; Lee, Y. J.; Hocek, Michal

    2013-01-01

    Roč. 21, č. 17 (2013), s. 5362-5372 ISSN 0968-0896 R&D Projects: GA ČR GAP207/11/0344 Institutional support: RVO:61388963 Keywords : nucleosides * pyrimido[4,5-b]indoles * Suzuki and Stille cross - coupling * anti-dengue virus activity Subject RIV: CC - Organic Chemistry Impact factor: 2.951, year: 2013

  18. Synthesis of azaphenanthridines via anionic ring closure

    DEFF Research Database (Denmark)

    Hansen, Henriette Møller; Lysén, M.; Begtrup, M.

    2005-01-01

    A new and convergent synthesis of azaphenanthridines via an anionic ring closure is reported. Ortho-lithiation/in situ borylation of cyanopyridines produces the corresponding cyanopyridylboronic esters, which undergo a Suzuki-Miyaura cross-coupling to give the key intermediates. Addition of lithium...

  19. Modular Approach to Heterogenous Catalysis. Manipulation of Cross-Coupling Catalyst Activity

    Czech Academy of Sciences Publication Activity Database

    Štibingerová, Iva; Voltrová, Svatava; Kočová, Šárka; Lindale, M.; Šrogl, Jiří

    2016-01-01

    Roč. 18, č. 2 (2016), s. 312-315 ISSN 1523-7060 R&D Projects: GA MŠk LH12012 Institutional support: RVO:61388963 Keywords : polysiloxane gels * Suzuki coupling * palladium nanoparticles Subject RIV: CC - Organic Chemistry Impact factor: 6.579, year: 2016

  20. Library of biphenyl privileged substructures using a safety-catch linker approach

    DEFF Research Database (Denmark)

    Severinsen, Rune; Bourne, Gregory T; Tran, Tran T

    2008-01-01

    A biphenyl privileged structure library containing three attachment points were synthesized using a catechol-based safety-catch linker strategy. The method requires the attachment of a bromo-acid to the linker, followed by a Pd-catalyzed Suzuki cross-coupling reaction. Further derivatization...

  1. Kimono Fusion - ultratraditsioonilisest hüpermoodsaks / Kelly Kipper

    Index Scriptorium Estoniae

    Kipper, Kelly

    2010-01-01

    Näitus "Kimono Fusion - ultratraditsioonilisest hüpermoodsaks" Stockholmis Östasiatiska muuseumis 10. jaanuarini 2010. Eksponeeritakse kimonosid ja obisid (traditsioonilised kimonovööd) ning jaapani moekunstnike loomingut. Lähemalt Shin Tanaka, Shojono Tomo, duo Takuya Angel'i (Takuya Sawada koos abikaasa Akikoga), Kunihiko Morinaga, Suzuki Takayuki loomingust

  2. Research Article

    African Journals Online (AJOL)

    2016-06-05

    Jun 5, 2016 ... Continuous use of opioids and dependence on these medications ... compartments were completely cleaned at the end of each experiment. ..... [11] Nakashima H, Katayama T, Honda Y, Suzuki S, Yano K, Cardioprotective effects of magnesium sulfate in patients undergoing primary coronary angioplasty for ...

  3. SSESSMENT OF CO2 EMISSION LEVEL IN URB N TR NSPORT OF ...

    African Journals Online (AJOL)

    USER

    2016-11-06

    Nov 6, 2016 ... allowing ease transfer of people, goods and services. It is also one of ... carbon dioxide, while Land cruiser and WllB car models; and Mercedes Benz and Suzuki motors emit more. ... pollution, urban heat island, and climate.

  4. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Pd immobilized on modified magnetic Fe₃O₄ nanoparticles: Magnetically recoverable and reusable Pd nanocatalyst for Suzuki-Miyaura coupling reactions and Ullmann-type N-arylation of indoles. RAMIN GHORBANI-VAGHEI SABA HEMMATI MALAK HEKMATI. Regular Article Volume 128 Issue 7 July 2016 pp 1157- ...

  5. Molecular Determinants of Hormone-Refractory Prostate Cancer

    Science.gov (United States)

    2015-07-01

    Suzuki Y, Honda G, et al. Large-scale identification and characterization of human genes that activate NF- kappaB and MAPK signaling pathways. Oncogene...2003 May 22;22(21):3307-18. Mendiratta P, et al. Genomic strategy for targeting therapy in castration-resistant prostate cancer. J Clin Oncol. 2009 Apr

  6. Fourth Power Diophantine Equations in Gaussian Integers

    Indian Academy of Sciences (India)

    25

    The method of Yasutaka Suzuki [9] determined all solutions of the equation. 2aXr +2bY s = 2cZt in ... Department of Pure Mathematics, Faculty of Science, Urmia University, Urmia 165-57153,. Iran. E-mail: ..... Japan Acad., 72,. Ser A, (1996). 9.

  7. SAJS SAJS

    African Journals Online (AJOL)

    Yellon DM, Baxter GF, Garcia-Dorado D, Heusch G, Sumeray MS. Ischae- mic preconditioning: present position and future directions. Cardiovasc Res. 1998 ... Lloris-Carsi JM, Cejalvo D, Toledo-Pereyra LH, Calvo MA, Suzuki S. Pre- conditioning: effect upon lesion modulation in warm ischaemia. Transplant. Proc 1993; 25: ...

  8. Rapid, facile synthesis of conjugated polymer zwitterions in ionic liquids

    Energy Technology Data Exchange (ETDEWEB)

    Page, Zachariah A. [Polymer Science & Engineering Department; Conte Center for Polymer Research; University of Massachusetts; Amherst, USA; Liu, Feng [Polymer Science & Engineering Department; Conte Center for Polymer Research; University of Massachusetts; Amherst, USA; Russell, Thomas P. [Polymer Science & Engineering Department; Conte Center for Polymer Research; University of Massachusetts; Amherst, USA; Emrick, Todd [Polymer Science & Engineering Department; Conte Center for Polymer Research; University of Massachusetts; Amherst, USA

    2014-01-01

    Ionic liquids (ILs) were utilized for the rapid air-stable Suzuki polymerization of polar zwitterionic thiophene monomers, precluding the need for volatile organic solvents, phosphine ligands and phase transfer catalysts typically used in conjugated polymer synthesis.

  9. Dead Wolves, Dead Birds, and Dead Trees: Catalysts for Transformative Learning in the Making of Scientist-Environmentalists

    Science.gov (United States)

    Walter, Pierre

    2013-01-01

    This historical study identifies catalysts for transformative learning in the lives of three scientist-environmentalists important to the 20th-century environmental movement: Aldo Leopold, Rachel Carson, and David Suzuki. Following a brief review of theoretical perspectives on transformative learning, the article argues that transformative…

  10. Burn Injury Caused by Laptop Computers

    African Journals Online (AJOL)

    generated in central processing unit (CPU), graphics processing unit, hard drive, internal ... change its position. Discussion ... Suzuki, et al. reported that the critical temperature for superficial burn was 37.8°C, for deep dermal burns 41.9°C and ... The laptop should be placed on a hard surface and not on soft surfaces like.

  11. Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate

    NARCIS (Netherlands)

    Mizutani, Makoto; Ito, Yasuhiko; Mizuno, Masashi; Nishimura, Hayato; Suzuki, Yasuhiro; Hattori, Ryohei; Matsukawa, Yoshihisa; Imai, Masaki; Oliver, Noelynn; Goldschmeding, Roel; Aten, Jan; Krediet, Raymond T.; Yuzawa, Yukio; Matsuo, Seiichi

    2010-01-01

    Mizutani M, Ito Y, Mizuno M, Nishimura H, Suzuki Y, Hattori R, Matsukawa Y, Imai M, Oliver N, Goldschmeding R, Aten J, Krediet RT, Yuzawa Y, Matsuo S. Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate. Am J Physiol

  12. Synthesis of (+)-Antroquinonol: An Antihyperglycemic Agent.

    Science.gov (United States)

    Sulake, Rohidas S; Lin, Hsiao-Han; Hsu, Chia-Yu; Weng, Ching-Feng; Chen, Chinpiao

    2015-06-19

    The total synthesis of antroquinonol has been accomplished through Suzuki-Miyaura cross-coupling and Barton-McCombie reaction, and the α,β-unsaturation was achieved through selenylation and oxidation protocols. In vitro and in vivo studies on the glucose-lowering properties of antroquinonol indicate that it is a potential antidiabetic agent.

  13. Sporadic simple groups and quotient singularities

    International Nuclear Information System (INIS)

    Cheltsov, I A; Shramov, C A

    2013-01-01

    We show that if a faithful irreducible representation of a central extension of a sporadic simple group with centre contained in the commutator subgroup gives rise to an exceptional (resp. weakly exceptional but not exceptional) quotient singularity, then that simple group is the Hall-Janko group (resp. the Suzuki group)

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Emerging trends at the interface of chemistry and biology: Applications to the ... Suzuki-Miyaura, Mizoroki-Heck carbon-carbon coupling and hydrogenation .... The change in colour can easily be distinguished from other metal complexes by the naked eye. .... Influence of magnetic field on the electrodeposition of Ni-Co alloy.

  15. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    The analysis revealed that the complexes possess a distorted octahedral geometry with the ligand coordinating in a uni-negative tridentate ONS fashion. The catalytic activity of complexes towards some C–C coupling reactions (viz., Kumada-Corriu, Suzuki-Miyaura and Sonogashira) has been examined. The complexes ...

  16. Improved Photovoltaic Performance of a Semicrystalline Narrow Bandgap Copolymer Based on 4H-Cyclopenta[2,1-b : 3,4-b ']dithiophene Donor and Thiazolo[5,4-d]thiazole Acceptor Units

    NARCIS (Netherlands)

    Van Mierloo, Sarah; Hadipour, Afshin; Spijkman, Mark-Jan; Van den Brande, Niko; Ruttens, Bart; Kesters, Jurgen; D'Haen, Jan; Van Assche, Guy; de Leeuw, Dago M.; Aernouts, Tom; Manca, Jean; Lutsen, Laurence; Vanderzande, Dirk J.; Maes, Wouter; Haen, Jan D’

    2012-01-01

    A solution processable narrow bandgap polymer composed of alternating 2,5-dithienylthiazolo[5,4-d]thiazole and asymmetrically alkyl-substituted 4H-cyclopenta[2,1-b:3,4-b']dithiophene units (PCPDT-DTTzTz) was synthesized by Suzuki polycondensation and the donor acceptor copolymer was thoroughly

  17. Browse Title Index

    African Journals Online (AJOL)

    Items 451 - 488 of 488 ... Vol 10, No 3 (2013), Video-assisted thoracoscopic double lobectomy for bronchiectasis: A case report and literature review, Abstract. T Takahashi, T Okazaki, T Doi, H Koga, K Suzuki, GJ Lane, A Yamataka. Vol 8, No 1 (2011), Vulnerability of children to gunshot trauma in violence-prone environment: ...

  18. Séminaire de probabilités XLVIII

    CERN Document Server

    Lejay, Antoine; Rouault, Alain

    2016-01-01

    In addition to its further exploration of the subject of peacocks, introduced in recent Séminaires de Probabilités, this volume continues the series’ focus on current research themes in traditional topics such as stochastic calculus, filtrations and random matrices. Also included are some particularly interesting articles involving harmonic measures, random fields and loop soups. The featured contributors are Mathias Beiglböck, Martin Huesmann and Florian Stebegg, Nicolas Juillet, Gilles Pags, Dai Taguchi, Alexis Devulder, Mátyás Barczy and Peter Kern, I. Bailleul, Jürgen Angst and Camille Tardif, Nicolas Privault, Anita Behme, Alexander Lindner and Makoto Maejima, Cédric Lecouvey and Kilian Raschel, Christophe Profeta and Thomas Simon, O. Khorunzhiy and Songzi Li, Franck Maunoury, Stéphane Laurent, Anna Aksamit and Libo Li, David Applebaum, and Wendelin Werner. .

  19. 'Exhibitions and experiments', in celebration of nobel prize in physics

    International Nuclear Information System (INIS)

    Hayashi, Masahito; Nakanishi, Akira; Nakano, Masahiro

    2010-01-01

    The Nobel Prize in Physics for 2008 was awarded to Professors Yoichiro Nambu, Makoto Kobayashi and Toshihide Maskawa. At this opportunity, we held an exhibition to introduce the achievements of the laureates for 10 days at the Omiya campus in May 2009. With the explanations of elementary particle physics, we prepared several experimental instruments with which visitors could play and learn the spontaneous symmetry breaking, cosmic rays, a circle path of an electron in a magnetic field and so on. Our main purpose of the exhibition was, however, not just to explain the contents of the Nobel Prize in Physics, but also to attract students' interests to physics. More than 800 individual students attended during the period, and the survey of questionnaires shows positive contributions to raise the students' awareness of the excitement of physics. (author)

  20. East Asia: Korea

    Science.gov (United States)

    1988-02-01

    fermenting within the parties as a result of the party standard-bearers and their subordi- nates’ different assessments of the causes of the defeat...Explosives, Korea Yogurt and Sammi Group each has four PhD’s, and Tong-yang Chemical, Pacific Chem- ical Group, Hanil Pharmaceutical, Korea Electrical...including insecticides by using microorganisms and pharmaceutical materials. Dr Sin Sok-pong, manager in the PCC, got his degree in fermentation

  1. Review of the Scientific Literature and Preparation of an Annotated Bibliography on Effects of Cigarette Smoking and Nicotine on Human Performance. Volume 1

    Science.gov (United States)

    1986-01-01

    documents involved ordering copies of reports from private or government libaries that contained infor- mation relevant to the effect of smoking and...series of digits to subjects singly at a rapid rate of 100 per minute. The task was to detect series of three consecutive odd or even digits . Alveolar...consecutive odd digits that occurred about once per minute (Tong at al., 1977)o Performance was measured by correct detections, and it was found that

  2. The development and validation of the Satisfaction Questionnaire for Osteoporosis Prevention in Malaysia

    OpenAIRE

    Lai, Pauline Siew Mei; Toh,Li Shean; Wong,Kok Thong; Tan,Alex Tong Boon; Low,Bee Yean; Anderson,Claire; Wu,David Bin-Chia

    2014-01-01

    Li Shean Toh,1 Pauline Siew Mei Lai,2 David Bin-Chia Wu,3 Kok Thong Wong,1 Bee Yean Low,1 Alexander Tong Boon Tan,4 Claire Anderson5 1School of Pharmacy, University of Nottingham, Semenyih, Malaysia; 2Department of Primary Care Medicine, University of Malaya Primary Care Research Group, University of Malaya, Kuala Lumpur, Malaysia; 3School of Pharmacy, Monash University Malaysia, Bandar Sunway, Malaysia; 4Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; 5Division of Soci...

  3. INSECT PHYLOGENOMICS. Response to Comment on "Phylogenomics resolves the timing and pattern of insect evolution".

    Science.gov (United States)

    Kjer, K M; Ware, J L; Rust, J; Wappler, T; Lanfear, R; Jermiin, L S; Zhou, X; Aspöck, H; Aspöck, U; Beutel, R G; Blanke, A; Donath, A; Flouri, T; Frandsen, P B; Kapli, P; Kawahara, A Y; Letsch, H; Mayer, C; McKenna, D D; Meusemann, K; Niehuis, O; Peters, R S; Wiegmann, B M; Yeates, D K; von Reumont, B M; Stamatakis, A; Misof, B

    2015-07-31

    Tong et al. comment on the accuracy of the dating analysis presented in our work on the phylogeny of insects and provide a reanalysis of our data. They replace log-normal priors with uniform priors and add a "roachoid" fossil as a calibration point. Although the reanalysis provides an interesting alternative viewpoint, we maintain that our choices were appropriate. Copyright © 2015, American Association for the Advancement of Science.

  4. A New Therapeutic Paradigm for Breast Cancer Exploiting Low Dose Estrogen-Induced Apoptosis

    Science.gov (United States)

    2012-06-01

    transcriptional repressor complex with RUNX3 [50], a known tumor suppressor that has been shown to be involved in apoptosis in gastric and colon cancer [51...A, et al. (2008) Apoptotic pathway induced by transduction of RUNX3 in the human gastric carcinoma cell line MKN-1. Cancer Sci 99: 23–30. 51. Tong DD...lung cancer risk in the cancer prevention study II nutrition cohort. Cancer Epidemiol Biomarkers Prev 2008;17:655-660. 115. Ramnath N, Menezes RJ

  5. KONVERSI ENERGI BIOMASSA KOTORAN SAPI MELALUI RANCANGAN BIODIGESTER UNTUK RUMAH TANGGA

    OpenAIRE

    I Gede Bawa Susana; I Made Suartika

    2017-01-01

    Biomassa kotoran sapi mengandung energi berupa gas metan yang dapat digunakan sebagai bahan bakar. Pengolahan biomassa kotoran sapi menjadi bahan bakar dilakukan melalui proses konversi energi dalam suatu biodigester. Biodigester dibuat untuk kebutuhan rumah tangga dengan kapasitas 0,5997 m3 untuk waktu penyimpanan 30 hari.  Masyarakat yang memelihara sapi 2-3 ekor dapat menggunakan biodigester tipe plastik dan fixed dome dengan kapasitas tong plastik 250 liter. Hasil pengujian menunjukkan ba...

  6. The Fate of Malathion on Copper and Iron Piping Within a Water Distribution System

    Science.gov (United States)

    2015-03-26

    application in biological, polymers and plastics , explosive, inorganic compounds as well as metal and alloy research (Dodd & Tonge, 1987). There are...submerged in a dielectric fluid [i.e. water] prior to the EDM sending an electrically charged brass wire over the sample. The wire disintegrated the...period, the coupon samples were removed from the glass vial, placed on a plastic sample holder, and allowed to dry in the desiccator for a four-hour

  7. Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia?reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice

    OpenAIRE

    Feng, Jiao; Zhang, Qinghui; Mo, Wenhui; Wu, Liwei; Li, Sainan; Li, Jingjing; Liu, Tong; Xu, Shizan; Fan, Xiaoming; Guo, Chuanyong

    2017-01-01

    Jiao Feng,1,* Qinghui Zhang,2,* Wenhui Mo,3,* Liwei Wu,1 Sainan Li,1 Jingjing Li,1 Tong Liu,1 Shizan Xu,4 Xiaoming Fan,5 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2Department of Clinical Laboratory, Kunshan First People’s Hospital Affiliated to Jiangsu University, Kunshan, JiangSu, 3Department of Gastroenterology, Minhang Hospital, Fudan University, Shanghai, 4Department of Gastroenter...

  8. Protective effect of galangin in Concanavalin A- induced hepatitis in mice

    OpenAIRE

    Luo Q; Zhu L; Ding J; Zhuang X; Xu L; Chen F

    2015-01-01

    Qingqiong Luo,1,* Liping Zhu,1,* Jieying Ding,1 Xing Zhuang,1 Lili Xu,2 Fuxiang Chen1 1Department of Clinical Immunology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, 2Division of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Galangin is an active pharmacological ingredient from propolis and Alpinia officinarum Hance, and has been r...

  9. Ultrasound molecular imaging of breast cancer in MCF-7 orthotopic mice using gold nanoshelled poly(lactic-co-glycolic acid) nanocapsules: a novel dual-targeted ultrasound contrast agent

    OpenAIRE

    Xu,Li; Du,Jing; Wan,Caifeng; Zhang,Yu; Xie,Shaowei; Li,Hongli; Yang,Hong; Li,Fenghua

    2018-01-01

    Li Xu,1,* Jing Du,1,* Caifeng Wan,1 Yu Zhang,1 Shaowei Xie,1 Hongli Li,1 Hong Yang,2 Fenghua Li1 1Department of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; 2Department of Chemistry, College of Life and Environmental Science, Shanghai Normal University, Shanghai, China *These authors contributed equally to this work Background: The development of nanoscale molecularly targeted ultrasound contrast agents (UCAs) with high affinity and specif...

  10. Protective effect of galangin in Concanavalin A-induced hepatitis in mice

    OpenAIRE

    Luo, Qingqiong; Zhu, Liping; Ding, Jieying; Zhuang, Xing; Xu, Lili; Chen, Fuxiang

    2015-01-01

    Qingqiong Luo,1,* Liping Zhu,1,* Jieying Ding,1 Xing Zhuang,1 Lili Xu,2 Fuxiang Chen1 1Department of Clinical Immunology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, 2Division of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Galangin is an active pharmacological ingredient from propolis and Alpinia officinarum Hance, an...

  11. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    The effects of β-elemene on the expression of mTOR, HIF-1α, surviving in lung adenocarcinoma A549 cell · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. E Tong, Y Xu, G Li, K Zou, L Zou, 18-23. http://dx.doi.org/10.4314/ajtcam.v10i4.4 ...

  12. Characterising the Ionosphere (La caracterisation de l’ionosphere)

    Science.gov (United States)

    2009-01-01

    2003; Valdivia , 2003; Tong et al ., 2004). Tidal motions and planetary waves in the thermosphere have significant influence on ionospheric...such as storms, earthquakes and volcanic explosions may produce F2-layer signatures (Rishbeth, 2006 ). Kazimirovsky et al . (2003) have reviewed such...possible effects. Pulinets et al . ( 2006 ) have published a case study of anomalous variations of the total electron content (TEC) registered over the

  13. Long-term results of a randomized controlled trial evaluating preoperative chemotherapy in resectable non-small cell lung cancer

    OpenAIRE

    Chen, Zhiwei; Luo, Qingquan; Jian, Hong; Zhou, Zhen; Cheng, Baijun; Lu, Shun; Liao, Meilin

    2013-01-01

    Zhiwei Chen,* Qingquan Luo,* Hong Jian, Zhen Zhou, Baijun Cheng, Shun Lu, Meilin LiaoShanghai Lung Tumor Clinical Medical Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China *These authors contributed equallyObjective: We aimed to evaluate whether preoperative chemotherapy provides benefits in the survival and prognosis of patients with non-small cell lung cancer (NSCLC) in resectable stages I to IIIA, except T1N0. Methods: In this ra...

  14. Metallic Material Image Segmentation by using 3D Grain Structure Consistency and Intra/Inter-Grain Model Information

    Science.gov (United States)

    2015-01-05

    Based on these research results, we built an interactive interface as a web application using the Django [9] web framework for the backend , and a...started from 2014) ∗ Partially supported by this AFOSR grant. Publications: 1. R. Meng, S. Nelakuditi, S. Wang, R. Choudhury. OmniView: A Mobile ...11. S. Singh, R. Meng, S. Nelakuditi, Y. Tong, S. Wang. SideEye: Mobile Assistant for Blind Spot Monitoring, International Conference on Computing

  15. Effect of irradiation on vitamin C and acidity

    International Nuclear Information System (INIS)

    Jiravatana, V.

    1971-01-01

    Effect of gamma radiation on the total carbohydrates content of Hom Tong banana stored for various time was discussed. The total carbohydrates of unirradiated banana increased more rapidly during storage than those of irradiated ones. Radiation did not appear to have any effect on the total carbohydrate content in the banana. No significant difference was found on the total carbohydrates between irradiated and unirradiated banana at the same stage of ripeness

  16. Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability

    OpenAIRE

    Dong, Xiaowei; Guo,Shujie; Pham,Kevin; Li,Diana; Penzak,Scott

    2016-01-01

    Shujie Guo,1 Kevin Pham,2 Diana Li,2 Scott R Penzak,3 Xiaowei Dong2 1State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Pharmaceutical Sciences, 3Department of Pharmacotherapy, University of North Texas Health Science Center, Fort Worth, TX, USA Purpose: The purpose of this study was to develop a novel lipid-based nanotechnology to...

  17. The endemiology of helicobacter pylorus infection and gastro-intestinal disease in mine and related factory workers of Tongling city, Anhui

    International Nuclear Information System (INIS)

    He Xiangyang; Jiang Zhonglin; Yang Shunqi; Mei Yanyan; Wen Qin; Cheng Yingzi; Wang Jianmiao

    2006-01-01

    Objective: To investigate the endemiology of H. pylorus infection and related gastro-intestinal disease in mine and factory workers of Tong-Ling area. Methods: 14 C-urea breath test, serum IgG and cytotoxin-producing H. pylorus antibodies determinations were performed in 1076 randomly selected adults among the mine and related factory workers in Tong - Ling area. Gastroscopy was done in 156 subjects (cytotoxin-producing H. pylorus antibody CagA-HP positive 108 and Cag-HP negative 48). Results: Seven hundred and twenty-one subjects of the 1076 (67.0%) examined were positive with the 14 C-urea breath and serological tests, among which 350 (48.5% of the 721 ) were Cag-HP positive. Factors affecting positiveness of HP infection were in the order of: working environment, gastro-intestinal symptoms, past history, vocation, age, history of previous contact, sex and non- hygiene life-style. Conclusion: The HP infection rate in Tong-Ling area was slightly higher than nationwide but with a lower CagA - HP positive rate. HP infection was mostly related to the working environment and life-style. (authors)

  18. Assessment of correlations and models for the prediction of CHF in water subcooled flow boiling

    Science.gov (United States)

    Celata, G. P.; Cumo, M.; Mariani, A.

    1994-01-01

    The present paper provides an analysis of available correlations and models for the prediction of Critical Heat Flux (CHF) in subcooled flow boiling in the range of interest of fusion reactors thermal-hydraulic conditions, i.e. high inlet liquid subcooling and velocity and small channel diameter and length. The aim of the study was to establish the limits of validity of present predictive tools (most of them were proposed with reference to light water reactors (LWR) thermal-hydraulic studies) in the above conditions. The reference dataset represents almost all available data (1865 data points) covering wide ranges of operating conditions in the frame of present interest (0.1 less than p less than 8.4 MPa; 0.3 less than D less than 25.4 mm; 0.1 less than L less than 0.61 m; 2 less than G less than 90.0 Mg/sq m/s; 90 less than delta T(sub sub,in) less than 230 K). Among the tens of predictive tools available in literature four correlations (Levy, Westinghouse, modified-Tong and Tong-75) and three models (Weisman and Ileslamlou, Lee and Mudawar and Katto) were selected. The modified-Tong correlation and the Katto model seem to be reliable predictive tools for the calculation of the CHF in subcooled flow boiling.

  19. Assessment of correlations and models for prediction of CHF in subcooled flow boiling

    International Nuclear Information System (INIS)

    Celata, G.P.; Mariani, A.; Cumo, M.

    1992-01-01

    This paper provides an analysis of available correlations and models for the prediction of Critical Heat Flux (CHF) in subcooled flow boiling in the ranges of interest of fusion reactor thermal-hydraulic conditions, i.e., high inlet liquid subcooling and velocity and small channel diameter and length. The aim of the study was to establish the limits of validity of present predictive tools (most of them were proposed with reference to LWR thermal-hydraulic studies) in the above conditions. The reference data-set represents most of available data covering wide ranges of operating conditions in the framework of present interest (0.1 s ub, in < 230 K). Among the tens of predictive tools available in literature, four correlations (Levy, Westinghouse, modified-Tong and Tong-75) and three models (Weisman and Ileslamlou Lee and Mudawar and Katto) were selected. The modified-Tong correlation and the Katto model seem to be reliable predictive tools for the calculation of the CHF in subcooled flow boiling

  20. Advances with microRNAs in Parkinson’s disease research

    Directory of Open Access Journals (Sweden)

    Ma L

    2013-10-01

    Full Text Available Liuqing Ma,1,2,* Liangming Wei,3,* Fei Wu,2,* Zhenhua Hu,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital affiliated with Shanghai JiaoTong University School of Medicine, Shanghai, People’s Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, Shanghai, People’s Republic of China; 3Research Institute of Micro/Nano Science and Technology, Shanghai JiaoTong University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Parkinson’s disease (PD is the second-most common age-dependent neurodegenerative disorder and is caused by severe degeneration of dopaminergic neurons in the substantia nigra pars compacta. Unfortunately, current treatment only targets symptoms and involves dopamine replacement therapy, which does not counteract progressive degeneration. MicroRNAs (miRNAs are a class of small RNA molecules implicated in post-transcriptional regulation of gene expression during development. Recent studies show that miRNAs are playing an important role in the pathophysiology of PD. miRNA-based therapy is a powerful tool with which to study gene function, investigate the mechanism of the disease, and validate drug targets. In this review, we focus on the recent advances of the use of miRNAs in the pathogenesis of PD. Keywords: miRNA, α-synuclein, LRRK2, miRNA-based therapy, pathophysiology

  1. Coercion, dissatisfaction, and social stigma: an ethnographic study of compensated living kidney donation in Iran.

    Science.gov (United States)

    Fry-Revere, Sigrid; Chen, Deborah; Bastani, Bahar; Golestani, Simin; Agarwal, Rachana; Kugathasan, Howsikan; Le, Melissa

    2018-02-26

    This article updates the qualitative research on Iran reported in the 2012 article by Tong et al. "The experiences of commercial kidney donors: thematic synthesis of qualitative research" (Tong et al. in Transpl Int 25:1138-1149, 2012). The basic approach used in the Tong et al. article is applied to a more recent and more comprehensive study of Iranian living organ donors, providing a clearer picture of what compensated organ donation is like in Iran since the national government began regulating compensated donation. Iran is the only country in the world where kidney selling is legal, regulated, and subsidized by the national government. This article focuses on three themes: (1) coercion and other pressures to donate, (2) donor satisfaction with their donation experience, and (3) whether donors fear social stigma. We found no evidence of coercion, but 68% of the paid living organ donors interviewed felt pressure to donate due to extreme poverty or other family pressures. Even though 27% of the living kidney donors interviewed said they were satisfied with their donation experience, 74% had complaints about the donation process or its results, including some of the donors who said they were satisfied. In addition, 84% of donors indicated they feared experiencing social stigma because of their kidney donation.

  2. Monitoring cancer stem cells: insights into clinical oncology

    Directory of Open Access Journals (Sweden)

    Lin SC

    2016-02-01

    Full Text Available ShuChen Lin,1,* YingChun Xu,2,* ZhiHua Gan,1 Kun Han,1 HaiYan Hu,3 Yang Yao,3 MingZhu Huang,4 DaLiu Min1 1Department of Oncology, Shanghai Sixth People’s Hospital East Campus, Shanghai Jiao Tong University, 2Department of Oncology, Renji Hospital, Shanghai Jiao Tong University, 3Department of Oncology, The Sixth People’s Hospital, Shanghai Jiao Tong University, 4Department of Medical Oncology, Cancer Hospital of Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Cancer stem cells (CSCs are a small, characteristically distinctive subset of tumor cells responsible for tumor initiation and progression. Several treatment modalities, such as surgery, glycolytic inhibition, driving CSC proliferation, immunotherapy, and hypofractionated radiotherapy, may have the potential to eradicate CSCs. We propose that monitoring CSCs is important in clinical oncology as CSC populations may reflect true treatment response and assist with managing treatment strategies, such as defining optimal chemotherapy cycles, permitting pretreatment cancer surveillance, conducting a comprehensive treatment plan, modifying radiation treatment, and deploying rechallenge chemotherapy. Then, we describe methods for monitoring CSCs. Keywords: cancer stem cells, glycolytic inhibition, watchful waiting, rechallenge, immunotherapy

  3. Variability in Treatment for Patients with Cervical Spine Fracture and Dislocation: An Analysis of 107,152 Patients.

    Science.gov (United States)

    Wang, Jing; Eltorai, Adam E M; DePasse, J Mason; Durand, Wesley; Reid, Daniel; Daniels, Alan H

    2018-06-01

    Cervical spine injuries are a common cause of morbidity and mortality; however, the optimal treatment of many of these injuries is debated, and previous studies have shown substantial variation in treatment. We sought to examined treatment variation in arthrodesis and halo/tong placement in cervical spine injury patients over a 12-year period. Data from the Healthcare Cost and Utilization Project National Inpatient Sample, from 2000 to 2011, were used for this study. Patients were identified with a cervical vertebral facture or dislocation based on the International Classification of Diseases, 9th Revision codes. Using χ 2 analysis, spinal arthrodesis rates and halo/tong placement rates were compared between hospitals based on teaching status for patients with and without spinal cord injury (SCI). The records of 107,152 patients with cervical fractures were examined. From 2000 to 2011, the overall arthrodesis rates fell from 25.2% to 20.6% (P < 0.001), and halo/tong placement rates fell from 13.2% to 3.6% (P < 0.001). In patients with cervical fracture without SCI, arthrodesis rates fell from 17.6% to 13.9% (P < 0.001), in cervical fracture patients with SCI, arthrodesis rates rose from 50.0% to 58.9% (P < 0.001), and in cervical dislocation patients, arthrodesis rates rose from 47.6% to 57.5% (P < 0.001). During the 12-year period, teaching hospitals had higher arthrodesis rates compared with nonteaching hospitals for patients with cervical fractures with SCI (57.3% vs. 53.4%, P = 0.001) and higher halo/tong placement rates for patients with cervical dislocations (2.7% vs. 1.7%, P = 0.004). Individual hospital variation showed a 3.5-fold variation in arthrodesis rates in 2000 to 2002, which fell to 3.0-fold by 2009 to 2011. Arthrodesis rates for cervical fracture patients significantly decreased, and arthrodesis rates for cervical dislocation and SCI patients increased from 2000 to 2011, with variability in treatment based on hospital teaching status

  4. Temperature dependence of bulk modulus and second-order elastic constants

    International Nuclear Information System (INIS)

    Singh, P.P.; Kumar, Munish

    2004-01-01

    A simple theoretical model is developed to investigate the temperature dependence of the bulk modulus and second order elastic constants. The method is based on the two different approaches viz. (i) the theory of thermal expansivity formulated by Suzuki, based on the Mie-Gruneisen equation of state, (ii) the theory of high-pressure-high-temperature equation of state formulated by Kumar, based on thermodynamic analysis. The results obtained for a number of crystals viz. NaCl, KCl, MgO and (Mg, Fe) 2 SiO 4 are discussed and compared with the experimental data. It is concluded that the Kumar formulation is far better that the Suzuki theory of thermal expansivity

  5. Preparation, structural characterization, and catalytic performance of Pd(II) and Pt(II) complexes derived from cellulose Schiff base

    Science.gov (United States)

    Baran, Talat; Yılmaz Baran, Nuray; Menteş, Ayfer

    2018-05-01

    In this study, we reported production, characterization, and catalytic behavior of two novel heterogeneous palladium(II) and platinum(II) catalysts derived from cellulose biopolymer. In order to eliminate the use of toxic organic or inorganic solvents and to reduce the use of excess energy in the coupling reactions, we have developed a very simple, rapid, and eco-friendly microwave irradiation protocol. The developed microwave-assisted method of Suzuki cross coupling reactions produced excellent reaction yields in the presence of cellulose supported palladium and platinum (II) catalysts. Moreover, the catalysts easily regenerated after simple filtration, and they gave good reusability. This study revealed that the designed catalysts and method provide clean, simple, rapid, and impressive catalytic performance for Suzuki coupling reactions.

  6. Matrix factorisations for rational boundary conditions by defect fusion

    International Nuclear Information System (INIS)

    Behr, Nicolas; Fredenhagen, Stefan

    2015-01-01

    A large class of two-dimensional N=(2,2) superconformal field theories can be understood as IR fixed-points of Landau-Ginzburg models. In particular, there are rational conformal field theories that also have a Landau-Ginzburg description. To understand better the relation between the structures in the rational conformal field theory and in the Landau-Ginzburg theory, we investigate how rational B-type boundary conditions are realised as matrix factorisations in the SU(3)/U(2) Grassmannian Kazama-Suzuki model. As a tool to generate the matrix factorisations we make use of a particular interface between the Kazama-Suzuki model and products of minimal models, whose fusion can be realised as a simple functor on ring modules. This allows us to formulate a proposal for all matrix factorisations corresponding to rational boundary conditions in the SU(3)/U(2) model.

  7. Perturbative many-body approaches to finite nuclei

    International Nuclear Information System (INIS)

    Hjort-Jensen, M.; Engeland, T.; Holt, A.; Osnes, E.

    1992-06-01

    In this work the authors discuss various approaches to the effective interaction appropriate for finite nuclei. The methods reviewed are the folded-diagram method of Kuo and co-workers and the summation of the folded diagrams as advocated by Lee and Suzuki. Examples of applications to sd-shell nuclei from previous works are discussed together with hitherto unpublished results for nuclei in pf-shell. Since the method of Lee and Suzuki is found to yield the best converged results, this method is applied to calculate the effective interaction for nuclei in the pf-shell. For the calculation of the effective interaction, three recent versions of the Bonn meson-exchange potential model have been used. These versions are fitted to the same set of data and differ only in the strength of the tensor force. The importance of the latter for finite nuclei is discussed. 67 refs., 17 figs., 7 tabs

  8. Development of radiography in Korea during Japanese colonial period

    International Nuclear Information System (INIS)

    Yoo, Hyung Sik

    2014-01-01

    After discovery of X-ray in 1895 by the Rontgen, the first X-ray equipment for medical use in Korea was installed at the Chosun Soutokufu Hospital in 1911. However the exact manufacturer or function of the equipment was not described. In 1913, Wappler X-ray equipment made in America was installed at the Severance Hospital which was operated by a surgeon named Mun-Jip Kang. Motoharu Suzuki was a Japanese doctor who had developed the radiology in Korea from 1922 to 1945. In 1934, he established the Chosun Rontgen Society. A number of articles on therapy and diagnosis have been reported mainly by Japanese doctors. The main topics were the diagnosis of pulmonary tuberculosis and barium of esophagus and stomach. Bu Hyun Lee, the first Korean radiologist who was trained by Suzuki from 1934 to 1937, published a radiology article in 1935 and organized the Korean Radiological Society in 1945.

  9. Matrix factorisations for rational boundary conditions by defect fusion

    Energy Technology Data Exchange (ETDEWEB)

    Behr, Nicolas [Department of Mathematics, Heriot-Watt University,Riccarton, Edinburgh, EH14 4AS (United Kingdom); Maxwell Institute for Mathematical Sciences,Edinburgh (United Kingdom); Fredenhagen, Stefan [Max-Planck-Institut für Gravitationsphysik, Albert-Einstein-Institut,D-14424 Golm (Germany)

    2015-05-11

    A large class of two-dimensional N=(2,2) superconformal field theories can be understood as IR fixed-points of Landau-Ginzburg models. In particular, there are rational conformal field theories that also have a Landau-Ginzburg description. To understand better the relation between the structures in the rational conformal field theory and in the Landau-Ginzburg theory, we investigate how rational B-type boundary conditions are realised as matrix factorisations in the SU(3)/U(2) Grassmannian Kazama-Suzuki model. As a tool to generate the matrix factorisations we make use of a particular interface between the Kazama-Suzuki model and products of minimal models, whose fusion can be realised as a simple functor on ring modules. This allows us to formulate a proposal for all matrix factorisations corresponding to rational boundary conditions in the SU(3)/U(2) model.

  10. Development of radiography in Korea during Japanese colonial period

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Hyung Sik [Dept. of Radiology, Kanyang University College of Medicine, Daejeon (Korea, Republic of)

    2014-12-15

    After discovery of X-ray in 1895 by the Rontgen, the first X-ray equipment for medical use in Korea was installed at the Chosun Soutokufu Hospital in 1911. However the exact manufacturer or function of the equipment was not described. In 1913, Wappler X-ray equipment made in America was installed at the Severance Hospital which was operated by a surgeon named Mun-Jip Kang. Motoharu Suzuki was a Japanese doctor who had developed the radiology in Korea from 1922 to 1945. In 1934, he established the Chosun Rontgen Society. A number of articles on therapy and diagnosis have been reported mainly by Japanese doctors. The main topics were the diagnosis of pulmonary tuberculosis and barium of esophagus and stomach. Bu Hyun Lee, the first Korean radiologist who was trained by Suzuki from 1934 to 1937, published a radiology article in 1935 and organized the Korean Radiological Society in 1945.

  11. What Is the Structure of the Antitubercular Natural Product Eucapsitrione?

    Science.gov (United States)

    Pullella, Glenn A; Wild, Duncan A; Nealon, Gareth L; Elyashberg, Mikhail; Piggott, Matthew J

    2017-07-21

    1,5,7-Trihydroxy-6H-indeno[1,2-b]anthracene-6,11,13-trione (1), proposed to be the antitubercular natural product eucapsitrione, has been synthesized in 43% overall yield and six steps, including a key Suzuki-Miyaura biaryl coupling and a directed remote metalation (DReM)-initiated cyclization. The physical and spectroscopic properties of 1 do not match the data reported for the natural product. At this time there is insufficient information available to enable a structure reassignment. During the optimization of the Suzuki-Miyaura coupling, an unprecedented biaryl coupling ortho to the borono group was observed. The scope of this unusual reaction has been investigated.

  12. Report on the international conference and bridge inspection in Singapore and Hong Kong. `97 Singapore and Hong Kong inspector group; Singapore Hong Kong no kokusai kaigi to kyoryo shisatsu hokoku. `97 Singapore Hong Kong shisatsudan

    Energy Technology Data Exchange (ETDEWEB)

    Abe, N.; Arai, H.; Shiota, R.; Takagaki, T.; Mori, T.

    1997-07-31

    The 4th International Symposium on Noteworthy Development in Prestressing and Precasting was held in Singapore in July 1997. The `97 Singapore and Hong Kong inspector group was organized by the Japan Prestressed Concrete Engineering Association to participate the symposium and inspect some bridges. The symposium consisted of reading of 17 presented papers (including questions and answers) related to introduction of PC and PCa structures of every country, PCa void lower slab for building floors, bridge, PCa joint, PCa residence, earthquake resistance, and structure analysis. Suzuki`s keynote address `Development and present state of PC road bridges in Japan` classified PC road bridges ranging from an early PC beam bridge to a recent PC cable stayed bridge and PC extra-dosed bridge for every kind and period, and systematically presented the growth of the Japanese highway network and PC bridge. The inspector group visited 3 bridges in Singapore, and 3 bridges in Hong Kong. 8 figs., 2 tabs.

  13. Investigating The Anti-apoptotic Effects of Shigella Flexneri Infection In Epithelial Cells

    Science.gov (United States)

    2009-08-13

    Infect. Immun. 72:6012-6022. 103. Suzuki, T., L. Franchi , C. Toma, H. Ashida, M. Ogawa, Y. Yoshikawa, H. Mimuro, N. Inohara, C. Sasakawa, and G... rule out the 106 possibility that a bacterial T3SS effector protein expressed intracellularly also contributes to the induction of JUN...of the point-counting stereological method (79) using an intraocular reticle of 27-mm diameter, covering 3578 μm 2 (Kr409, Klarman Rulings ) (68

  14. Synthesis of Functionalized Arylaziridines as Potential Antimicrobial Agents

    Directory of Open Access Journals (Sweden)

    Arianna Giovine

    2014-08-01

    Full Text Available By using the Suzuki-Miyaura protocol, a simple straightforward synthesis of functionalized 2-arylaziridines has been developed. By means of this synthetic strategy from readily available ortho-, meta- and para-bromophenylaziridines and aryl- or heteroarylboronic acids, new aziridines could be obtained. The cross-coupling reactions occurred without ring opening of the three membered ring. Preliminary results on the antimicrobial activity of the heterosubstituted biaryl compounds have been also included.

  15. Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions

    KAUST Repository

    Benhamou, Laure

    2014-01-13

    PEPPSI complexes incorporating chiral N-heterocyclic carbene (NHC) ligands based on 2,2-dimethyl-1-(o-substituted aryl)propan-1-amines were synthesized. Two complexes, with one saturated and one unsaturated NHC ligand, were structurally characterized. The chiral PEPPSI complexes were used in asymmetric Suzuki-Miyaura reactions, giving atropisomeric biaryl products in modest to good enantiomeric ratios. © 2013 American Chemical Society.

  16. A revised subgeneric position for Polypedilum (Probolum) simantokeleum, with description of a new Uresipedilum species in Japan (Diptera: Chironomidae).

    Science.gov (United States)

    Yamamoto, Nao; Yamamoto, Masaru

    2015-08-11

    Two Japanese Polypedilum species including a new species are redescribed and described based on the males. Polypedilum (Probolum) simantokeleum, Sasa, Suzuki et Sakai, 1998, is transferred to the subgenus Uresipedilum. Polypedilum (Uresipedilum) dissimilum sp. nov. is easily distinguished from other members of Uresipedilum by having a T-shaped tergal band. Definition of the subgenus Probolum is briefly discussed: we suggest Probolum should be defined as the species with the superior volsella bearing inner lobe pending adequate larval information.

  17. A contribution to the systematics of Australasian Tanytarsini (Diptera: Chironomidae): first descriptions from New Caledonia.

    Science.gov (United States)

    Giłka, Wojciech; Dobosz, Roland

    2015-06-26

    First specific records of chironomids of the tribe Tanytarsini from New Caledonia based on detailed descriptions of new species are presented. Cladotanytarsus (Cladotanytarsus) stylifer sp. nov. and its closest relatives, i.a. Cladotanytarsus (C.) isigacedeus (Sasa et Suzuki, 2000), comb. nov., known from males bearing extraordinarily elongate hypopygial anal points are diagnosed. Paratanytarsus mirificus sp. nov. is described as adult male with unique structure of its hypopygium and shortened antennae. Diagnostic description of Tanytarsus fuscithorax Skuse, 1889 is also complemented.

  18. Short-time synthesis of poly[4,6-bis(3′-(2-ethylhexyl)thien-2′-yl)thieno[3,4-c][1,2,5]thiadiazole-alt-9,9-dioctylfluorene], its photophysical, electrochemical and photovoltaic properties

    Czech Academy of Sciences Publication Activity Database

    Cimrová, Věra; Kmínek, Ivan; Výprachtický, Drahomír; Pokorná, Veronika

    2015-01-01

    Roč. 59, 24 February (2015), s. 298-304 ISSN 0032-3861 R&D Projects: GA ČR(CZ) GA13-26542S; GA ČR GAP106/12/0827 Institutional support: RVO:61389013 Keywords : low-bandgap thienothiadiazole copolymer * Suzuki coupling * photophysics and photovoltaics Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.586, year: 2015

  19. Application of “Boomerang” Linear Polystyrene-Stabilized Pd Nanoparticles to a Series of C-C Coupling Reactions in Water

    Directory of Open Access Journals (Sweden)

    Atsushi Ohtaka

    2015-02-01

    Full Text Available The application of a catch-and-release system for soluble Pd species between water (reaction medium and polystyrene (polymer support was examined in the Suzuki coupling reaction with 2-bromothiophene and the Heck reaction with styrene or bromobenzene. Although a slight increase in particle size was observed by TEM after re-stabilization of the Pd species on linear polystyrene, no agglomeration was observed.

  20. Perceived parental affectionless control is associated with high neuroticism

    OpenAIRE

    Takahashi,Nana; Suzuki,Akihito; Matsumoto,Yoshihiko; Shirata,Toshinori; Otani,Koichi

    2017-01-01

    Nana Takahashi, Akihito Suzuki, Yoshihiko Matsumoto, Toshinori Shirata, Koichi Otani Department of Psychiatry, Yamagata University School of Medicine, Yamagata, Japan Objective: Depressed patients are prone to perceive that they were exposed to affectionless control by parents. Meanwhile, high neuroticism is a well-established risk factor for developing depression. Therefore, this study examined whether perceived parental affectionless control is associated with high neuroticism.Methods: Th...

  1. Visual monitoring of solid-phase extraction using chromogenic fluorous synthesis supports.

    Science.gov (United States)

    Blackburn, Christopher

    2012-03-12

    Reductive aminations and further transformations of an azo dye and fluorous tagged aldehyde are described. The intensely colored 2,4-dialkoxybenzyl protected amines undergo Fmoc-based peptide coupling, Suzuki reactions, and sulfonamide formation with product isolation facilitated by visual monitoring of fluorous solid phase extraction. Target compounds are released from the supports in high yields and purities by treatment with trifluoroacetic acid (TFA).

  2. The First Total Synthesis of Dragmacidin D

    OpenAIRE

    Garg, Neil K.; Sarpong, Richmond; Stoltz, Brian M.

    2002-01-01

    The first total synthesis of the biologically significant bis-indole alkaloid dragmacidin D (5) has been achieved. Thermal and electronic modulation provides the key for a series of palladium-catalyzed Suzuki cross-coupling reactions that furnished the core structure of the complex guanidine- and aminoimidazole-containing dragmacidins. Following this crucial sequence, a succession of meticulously controlled final events was developed leading to the completion of the natural product.

  3. Revision of Sciaphila (Triuridaceae in Taiwan

    Directory of Open Access Journals (Sweden)

    Tsung-Hsin Hsieh

    2003-12-01

    Full Text Available The genus Sciaphila (Triuridaceae is revised based on comparative morphological and palynological studies in Taiwan. Four species are recognized, i. E. Sciaphila arfakiana Becc., S. Maculata Miers, S. ramosa Fukuy. & T. Suzuki, and S. secundiflora Thwaites ex Benth. Sciaphila arfakiana and S. maculata are new record to Flora of Taiwan and S. secundiflora distributed in Kueishan Island is a new distribution. SEM micrographs of pollen grains, a key to species, species descriptions, and taxonomic notes are provided.

  4. Nonreductive WZW models and their CFTs, 2: N = 1 and N = 2 cosets

    International Nuclear Information System (INIS)

    Figueroa-O'Farrill, J.

    1996-09-01

    We started a programme devoted to the systematic study of the conformal field theories derived from WZW models based on nonreductive Lie groups. In this, the second part, we continue this programme with a look at the N = 1 and N = 2 superconformal field theories which arise from both gauged and ungauged supersymmetric WZW models. We extend the supersymmetric (affine) Sugawara and coset constructions, as well as the Kazama-Suzuki construction to general self-dual Lie algebras. (author). 29 refs

  5. По зимнему бездорожью на полном приводе / Велиматти Хонканен, Яри Питкаярви и Ярмо Сукава

    Index Scriptorium Estoniae

    Хонканен, Велиматти

    2003-01-01

    Audi A4 1,8 T Quattro, BMW 325Xi, Honda HR-V 1,6i, Jaguar X-Type 3,0 V6, Mercedes-Benz E 320 4matic, Renault Scenic RX4 2,0, Škoda Octavia Combi 2,0WD, Subaru Impreza 2,0 GX, Suzuki Liana 1,6 4WD, Volvo S60 AWD

  6. Diversification of indoles via microwave-assisted ligand-free copper-catalyzed N-arylation

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Jae Kwan; Lee, Jin Hee; Kim, Tae Sung; Yum, Eul Kgun [Dept. of Chemistry, Chu ngnam National University, Daejon (Korea, Republic of); Park, Jee Jung [Western Seoul Center Korea Basic Science Institute, Seoul (Korea, Republic of)

    2016-12-15

    A simple, efficient Cu{sub 2}O catalyst system under microwave irradiation was developed for N-arylation of various indoles without ligands and additives. Diverse N-heteroarylated indoles were prepared by coupling indoles with various heteroaryl halides within 1 h. The selective reactivity of bromoindole with aryl iodide provided N-aryl bromoindoles, which could be useful intermediates for palladium-catalyzed Heck and Suzuki coupling reactions.

  7. Singular vectors of Malikov-Fagin-Fux in topological theories

    International Nuclear Information System (INIS)

    Semikhatov, A.M.

    1993-01-01

    Coincidence of singular vectors in relation to the sl(2) Katza-Mudi algebra and the algebra of the N=2 (twisted) supersymmetry is established. On the base of the Kazama-Suzuki simplest model is obtained a representation for the sl(2) currents in terms of an interacting with mater gravitation. From the Malikov-Fagin-Fux formulae for the sl(2) singular currents is obtained the general expression for singular vectors in topological theories

  8. Synthesis of Some Green Dopants for OLEDs Based on Arylamine 2,3-disubstituted Bithiophene Derivatives

    Directory of Open Access Journals (Sweden)

    Mi-Seon Song

    2013-11-01

    Full Text Available A series of green dopants based on 2,2-diphenylvinyl end-capped bithiophene and three different arylamine moieties (9-phenylcarbazole, triphenylamine, and N,N’-di-(p-tolylbenzeneamine were successfully synthesized by the Suzuki and Wittig coupling reactions. The photophysical properties of these compounds are reported. The strongest PL emitting compound with the 9-phenylcarbazole moiety has been used for fabricating an OLED device with good overall performance.

  9. Floating Ocean Platform

    Science.gov (United States)

    2003-08-15

    Proc ICOSSAR 89 5th Int Conf Struct Saf Reliab, 1989, p 183-190 Fukusumi, Tadahiro (Kobe Univ); Kusakabe, Kaoru , Dynamic response 162 characteristics...Harbor Research Institute, Ministry of Transport, Japan, October, 348--359, 1994 Maeda, N. and Morikawa, M. and Ishikawa , K. and Kakuta, Y., Fatigue...Harbor Research Institute, Ministry of Transport, Japan, October, 383--394, 1994 Morikawa, M. and Suzuki, H. and Ishikawa , K. and Komiya, H. and Yoshida

  10. The Use of Filariae as a Therapeutic Agent for Hypersensitivity Diseases

    Science.gov (United States)

    2014-12-01

    come into contact with the allergen. These cytokines activate innate lymphoid cells (ILCs) and help dendritic cells (DCs) polarize a Th2 environment...Experimental Allergy 40:299-306 58. Filbey KJ, Grainger JR, Smith KA, Boon L, van Rooijen N, et al. 2014. Innate and adaptive type 2 immune cell ...105. Kamijo S, Takeda H, Tokura T, Suzuki M, Inui K, et al. 2013. IL-33–mediated innate response and adaptive immune cells contribute to maximum

  11. JPRS Report, Near East & South Asia, Israel

    Science.gov (United States)

    1991-09-11

    practice, however, a but I never heard him; I have enough music here at the good number of ceremonies are held at the Western Western Wall." Wall...Israel on the volume Company, Daihatsu, Suzuki, Sony , Hitachi, and others. of their purchases from Israeli industry. Golan: "We are certain that, under...Kibbutz that arrived in the corresponding period last year. How- Yad Mordekhai, an entertainment center on the Dead ever, in recent months, the branch

  12. A Biomechanical Model of Single-joint Arm Movement Control Based on the Equilibrium Point Hypothesis

    OpenAIRE

    Masataka, SUZUKI; Yoshihiko, YAMAZAKI; Yumiko, TANIGUCHI; Department of Psychology, Kinjo Gakuin University; Department of Health and Physical Education, Nagoya Institute of Technology; College of Human Life and Environment, Kinjo Gakuin University

    2003-01-01

    SUZUKI,M., YAMAZAKI,Y. and TANIGUCHI,Y., A Biomechanical Model of Single-joint Arm Movement Control Based on the Equilibrium Point Hypothesis. Adv. Exerc. Sports Physiol., Vol.9, No.1 pp.7-25, 2003. According to the equilibrium point hypothesis of motor control, control action of muscles is not explicitly computed, but rather arises as a consequence of interaction among moving equilibrium point, reflex feedback and muscle mechanical properties. This approach is attractive as it obviates the n...

  13. Fires, A Joint Professional Bulletin for US Field & Air Defense Artillerymen. July-August 07

    Science.gov (United States)

    2007-08-01

    Zafaraniya area of southeast Baghdad in the Karada Security District. (Photo by SSgt Bronco Suzuki, USAF) The Fires staff wishes to thank RCW...not “cut and run.” External Support. The UN was suc- cessful in stabilizing El Salvador after an exceptionally bloody civil war, in large part by...involving neighboring states that were desperate to keep the conflict from spilling over El Salvador’s borders onto their soil. A family in Northern

  14. Synthesis of E-Alkyl Alkenes from Terminal Alkynes via Ni-Catalyzed Cross-Coupling of Alkyl Halides with B-Alkenyl-9-borabicyclo[3.3.1]nonanes.

    Science.gov (United States)

    Di Franco, Thomas; Epenoy, Alexandre; Hu, Xile

    2015-10-02

    The first Ni-catalyzed Suzuki-Miyaura coupling of alkyl halides with alkenyl-(9-BBN) reagents is reported. Both primary and secondary alkyl halides including alkyl chlorides can be coupled. The coupling method can be combined with hydroboration of terminal alkynes, allowing the expedited synthesis of functionalized alkyl alkenes from readily available alkynes with complete (E)-selectivity in one pot. The method was applied to the total synthesis of (±)-Recifeiolide, a natural macrolide.

  15. The Role of Estrogen Related Receptor in Modulating Estrogen Receptor Mediated Transcription in Breast Cancer Cells

    Science.gov (United States)

    2005-04-01

    tumors correlates with an unfavorable prognosis (Ariazi 2002; Lu 2001; Suzuki 2004; Vanacker 1999). The transcriptional activity of ERRa is not inhibited...SA. 101:6570-5. Needham, M ., S. Raines, J. McPheat, C. Stacey, J. Ellston, S. Hoare, and M . Parker. 2000. Differential interaction of steroid hormone...R. Graves, M . Wright, and B.M. Spiegelman. 1998. A cold- inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92:829- 39

  16. Factors in Maximal Power Production and in Exercise Endurance Relative to Maximal Power

    Science.gov (United States)

    1988-10-13

    Mechanical efficiency of fast -and slow - twitch muscle fibers in mnan during cycling. J. ADLi Physiol.:Reespirat. Environ. Exercise Physiol. 47: 263- 267...R.S. Hikida, and F.C. Hagerman. Myofibrillar ATPase activity in hu-man muscle fast - twitch subtypes. Histochem. 78: 405-408, 1983. 31. Suzuki, Y...capacity and muscle fibre composition in mnan. J. Physiol (London) 354: 73P, 1984. 21. Margaria, R., P. Aghemo, and E. Rovelli. Measurement of muscular

  17. Synthesis of novel kavain-like derivatives and evaluation of their cytotoxic activity

    Energy Technology Data Exchange (ETDEWEB)

    Amaral, Patricia de A.; Agustini, Taciane; Eifler-Lima, Vera L. [Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre (Brazil). Faculdade de Farmacia. Lab. de Sintese Organica Medicinal; Petrignet, Julien; Cariou, Alexandre; Gree, Rene [Universite de Rennes 1, Rennes (France). Lab. de Chimie Therapeutique; Gouault, Nicolas; Lohezic-Ledevehat, Francoise; David, Michele [CNRS UMR, Universite de Rennes 1, Rennes (France). Lab. de Chimie et Photonique Moleculaires

    2009-07-01

    Palladium-catalyzed cross coupling reactions (Sonogashira-Hagihara, Suzuki-Miyaura, and Heck) coupling and nickel hydride-mediated tandem isomerization aldolisation have been used for the synthesis of three series of {delta}-valerolactones substituted in positions 3, 4, 5 and 6 of the lactone ring. The 26 kavaien-like derivatives were tested against three cell lines and five of them exhibited a weak cytotoxic activity. (author)

  18. Few-body problem in terms of correlated Gaussians

    Science.gov (United States)

    Silvestre-Brac, Bernard; Mathieu, Vincent

    2007-10-01

    In their textbook, Suzuki and Varga [Stochastic Variational Approach to Quantum-Mechanical Few-Body Problems (Springer, Berlin, 1998)] present the stochastic variational method with the correlated Gaussian basis in a very exhaustive way. However, the Fourier transform of these functions and their application to the management of a relativistic kinetic energy operator are missing and cannot be found in the literature. In this paper we present these interesting formulas. We also give a derivation for formulations concerning central potentials.

  19. Synthesis and Characterization of New Thieno[3,2-b]thiophene Derivatives

    Directory of Open Access Journals (Sweden)

    Wojciech Pisula

    2012-10-01

    Full Text Available Three derivatives of thieno[3,2-b]thiophene end-capped with phenyl units have been synthesized and characterized by MALDI TOF mass spectroscopy, elemental analysis, UV-vis absorption spectroscopy and thermogravimetric analysis (TGA. All compounds were prepared using Pd-catalyzed Stille or Suzuki coupling reactions. Optical measurements and thermal analysis revealed that these compounds are promising candidates for p-type organic semiconductor applications.

  20. Social–Emotional Factors Affecting Achievement Outcomes Among Disadvantaged Students: Closing the Achievement Gap

    OpenAIRE

    Becker, Bronwyn E.; Luthar, Suniya S.

    2002-01-01

    Despite concentrated efforts at improving inferior academic outcomes among disadvantaged students, a substantial achievement gap between the test scores of these students and others remains (Jencks & Phillips, 1998; National Center for Education Statistics, 2000a, 2000b; Valencia & Suzuki, 2000). Existing research used ecological models to document social–emotional factors at multiple levels of influence that undermine academic performance. This article integrates ideas from various perspecti...

  1. A Parallel Algorithm for Connected Component Labelling of Gray-scale Images on Homogeneous Multicore Architectures

    International Nuclear Information System (INIS)

    Niknam, Mehdi; Thulasiraman, Parimala; Camorlinga, Sergio

    2010-01-01

    Connected component labelling is an essential step in image processing. We provide a parallel version of Suzuki's sequential connected component algorithm in order to speed up the labelling process. Also, we modify the algorithm to enable labelling gray-scale images. Due to the data dependencies in the algorithm we used a method similar to pipeline to exploit parallelism. The parallel algorithm method achieved a speedup of 2.5 for image size of 256 x 256 pixels using 4 processing threads.

  2. Vapor Pressure of N,N’-Diisopropylcarbodiimide (DICDI)

    Science.gov (United States)

    2016-02-01

    11. Furumoto, S. The Synthesis of Carbodiimides from N,N-Disubstituted Thioureas and 2- Chloro-4,6-dimethylpyrimidine, 2,4-Dichloropyrimidine or...N-Phenylbenzimidoyl Chloride . Journal of Synthetic Organic Chemistry, Japan 1975, 33, 748–752. 12. Kagami, H.; Hanzawa, N.; Suzuki, N.; Yamaguchi...25. Brozena, A.; Buchanan, J.H.; Miles, R.W., Jr.; Williams, B.R.; Hulet, M.S. Vapor Pressure of Triethyl and Tri-n- Propyl Phosphates and Diethyl

  3. Controlled immobilization of palladium nanoparticles in two different fluorinated polymeric aggregate cores and their application in catalysis

    DEFF Research Database (Denmark)

    Kijima, Tetsushi; Javakhishvili, Irakli; Jankova Atanasova, Katja

    2012-01-01

    Fluoroalkyl end-capped betaine-type cooligomeric nanocomposites-immobilized palladium nanoparticles were prepared by the reactions of palladium chloride with sodium acetate in the presence of sodium chloride and the corresponding fluorinated cooligomers. Outer blocks of poly(2,3,4,5,6-pentafluoro....... These fluorinated nanocomposites-immobilized palladium nanoparticles were also applied to the catalysts for Suzuki-Miyaura cross-coupling reaction, and the different reactivity between these nanocomposites was observed....

  4. Microwave-assisted and conventional synthesis, photophysics and electroluminescence of poly(9,9-dihexadecylfluorene-2,7-diyl-alt-2,2′-bithiophene-5,5′-diyl)

    Czech Academy of Sciences Publication Activity Database

    Dzhabarov, Vagif; Výprachtický, Drahomír; Cimrová, Věra

    2018-01-01

    Roč. 98, January (2018), s. 420-429 ISSN 0014-3057 R&D Projects: GA ČR(CZ) GA13-26542S Institutional support: RVO:61389013 Keywords : dialkylfluorene-bithiophene copolymers * microwave-assisted heating * Suzuki coupling Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 3.531, year: 2016

  5. Analisa Pengaruh Bauran Pemasaran terhadap Minat Beli Ulang Sepeda Motor Honda Kategori Sport Mid

    OpenAIRE

    Kartika, Eric Kusnadi

    2014-01-01

    The growth of the industry motorcycles in Indonesia continues to increase. As more and more brands of motorcycle industry, such as Honda, Yamaha, Suzuki, and others, causing consumers are faced with many alternative brands. Based on the data obtained from PT. Daya Adicipta Mustika as Honda Motorcycles Main Dealer in West Java, it is known that Honda Motorcycles brand has the highest sales volume in the motorcycle industry in Indonesia. However, it is known that there is one category of Honda ...

  6. Off-Axis Ratcheting Behavior of Unidirectional Carbon/Epoxy Laminate under Asymmetric Cyclic Loading at High Temperature

    Science.gov (United States)

    2011-11-01

    ply unidirectional carbon/epoxy laminates [0]12 were fabricated from the prepreg tape of P3252-20 (TORAY). They were laid up by hand and cured in...Off-Axis Ratcheting Behavior of Unidirectional Carbon/Epoxy Laminate under Asymmetric Cyclic Loading at High Temperature Takafumi Suzuki 1 and...Development of an engineering model for predicting the off-axis ratcheting behavior of a unidirectional CFRP laminate has been attempted. For this purpose

  7. Synthesis, characterization and catalytic utilization of a ferrocene diamidodiphosphane

    Czech Academy of Sciences Publication Activity Database

    Štěpnička, P.; Schulz, J.; Císařová, I.; Fejfarová, Karla

    2007-01-01

    Roč. 72, č. 4 (2007), s. 453-467 ISSN 0010-0765 Grant - others:GAMŠk(CZ) LC06070 Program:LC Institutional research plan: CEZ:AV0Z10100521 Keywords : ferrocene * phosphines * amides * Suzuki-Miyaura cross-coupling, crystal structure determination * igands * x-ray diffraction Subject RIV: CA - Inorganic Chemistry Impact factor: 0.879, year: 2007

  8. Biosynthesis of Enterobacterial Common Antigen: The ECA-Trace Phenotype of Salmonella Typhimurium and The Role of the rfe Gene in 08 Side-Chain Synthesis in Escherichia Coli

    Science.gov (United States)

    1993-03-18

    hitherto unidentified class of compounds for procaryotes . There are several possible explanations for the occurrence of lipids IIa and lIb . The first...SalOJoneiia TypbiOJuriUOl. Cellular and Molecular Biology .. Vol. I. American Society For Microbiology. Washington. D. C. Galanos. C. 0 .. and E. T...ill: 3697-3702 Hirota,Y. , H. Suzuki, Y. Nishimura, S. Yasuda. 1977. On the process of cellular division in Escherichia coli: a mutant of £. coli

  9. Bone integration capability of nanopolymorphic crystalline hydroxyapatite coated on titanium implants

    OpenAIRE

    Ogawa, Takahiro; Yamada,Masahiro; Ueno,; Tsukimura,Naoki; Ikeda,; Nakagawa,; Hori,; Suzuki,

    2012-01-01

    Masahiro Yamada*, Takeshi Ueno*, Naoki Tsukimura, Takayuki Ikeda, Kaori Nakagawa, Norio Hori, Takeo Suzuki, Takahiro OgawaLaboratory of Bone and Implant Sciences, The Weintraub Center for Reconstructive Biotechnology, Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry, UCLA School of Dentistry, Los Angeles, CA, USA *These authors contributed equally to this workAbstract: The mechanism by which hydroxyapatite (HA)-coated titanium promotes bone–implant integratio...

  10. C P Singh

    Indian Academy of Sciences (India)

    ... Simon-Gillo C P Singh V Singh M Sivertz A Soldatov R A Soltz S Sorensen P W Stankus N Starinsky P Steinberg E Stenlund A Ster S P Stoll M Sugioka T Sugitate J P Sullivan Y Sumi Z Sun M Suzuki E M Takagui A Taketani M Tamai K H Tanaka Y Tanaka E Taniguchi M J Tannenbaum J Thomas J H Thomas T L Thomas ...

  11. Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions

    KAUST Repository

    Benhamou, Laure; Besnard, Cé line; Kü ndig, E. Peter

    2014-01-01

    PEPPSI complexes incorporating chiral N-heterocyclic carbene (NHC) ligands based on 2,2-dimethyl-1-(o-substituted aryl)propan-1-amines were synthesized. Two complexes, with one saturated and one unsaturated NHC ligand, were structurally characterized. The chiral PEPPSI complexes were used in asymmetric Suzuki-Miyaura reactions, giving atropisomeric biaryl products in modest to good enantiomeric ratios. © 2013 American Chemical Society.

  12. Stemcell Information: SKIP000195 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available illin, 50 mg/mL streptomycin, and 1 mM L-glutamine ... Daisuke Ito 伊東 大介 Keio University 慶應義塾大学医学...部神経内科 Keio University 慶應義塾大学医学部神経内科 Norihiro Suzuki 鈴木 則宏 Not Available Keio University 慶應義塾大学医学

  13. Stemcell Information: SKIP000194 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available lin, 50 mg/mL streptomycin, and 1 mM L-glutamine ... Daisuke Ito 伊東 大介 Keio University 慶應義塾大学医学...部神経内科 Keio University 慶應義塾大学医学部神経内科 Norihiro Suzuki 鈴木 則宏 Not Available Keio University 慶應義塾大学医学

  14. Investigation on the dynamic response and strength of very long floating structures by beam modeling on an elastic foundation; Dansei shishojo no hari model ni yoru chodai futai kozo no doteki tawami kyodo tokusei ni kansuru kosatsu

    Energy Technology Data Exchange (ETDEWEB)

    Tsubogo, T.; Okada, H. [University of Osaka Prefecture, Osaka (Japan). Faculty of Engineering

    1997-08-01

    A very large floating structure was replaced with the beam on an elastic foundation to examine the response characteristics in waves. Another evidence was regularly and numerically given for the basic characteristics of a very large floating body Suzuki found. New information was also obtained. The frequency response is mainly classified into a wave number control area and proper frequency control area when buoyancy elasticity exists. When the buoyancy structure is long and flexible, the proper frequency becomes continuous and the frequency control area becomes a resonance area. In the wave number control area, the Suzuki`s characteristic wave number becomes a control parameter, and various characteristic values are indicated by characteristic wave numbers. The response in the wave number control area becomes quasi-static when the distribution mass of buoyancy is fully small. The design in which the distribution mass of buoyancy is fully large must be avoided. In the displacement amplitude, the mass on the free end is severest. The proper frequency of vertical vibration relatively moves to the high-frequency side when buoyancy is considered as an elastic foundation. Attention must be thus paid to the proper frequency of vibration on the horizontal surface. 9 refs., 12 figs., 3 tabs.

  15. What strategies do ulcerative colitis patients employ to facilitate adherence?

    Directory of Open Access Journals (Sweden)

    Kawakami A

    2017-01-01

    Full Text Available Aki Kawakami,1,2 Makoto Tanaka,3 Makoto Naganuma,4 Shin Maeda,5 Reiko Kunisaki,1 Noriko Yamamoto-Mitani2 1Inflammatory Bowel Disease Center, Yokohama City University Medical Center, Minami-ku, Yokohama, Japan; 2Department of Gerontological Home Care and Long-term Care Nursing, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan; 3Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchathewi, Bangkok, Thailand; 4Division of Gastroenterology and Hepatology, Keio University, Shinjuku-ku, Tokyo, Japan; 5Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Yokohama, Japan Background: Overall, 30%–45% of patients with ulcerative colitis (UC are non-adherent and have difficulties taking their medications; this non-adherence increases the risk of clinical relapse 1.4- to 5.5-fold. This study aimed to clarify the strategies patients employ to facilitate adherence and determine whether the strategies had an impact on good adherence.Methods: This was a cross-sectional survey using a self-administered questionnaire and review of medical records. Patients diagnosed as having UC and attending one of the outpatient clinics of four urban hospitals from June 2009 to December 2012 were enrolled. A questionnaire was developed to identify the strategies patients employ to facilitate adherence and then administered to patients with UC. Adherence to 5-aminosalicylic acid was calculated, and univariate and multiple logistic regression analyses were performed to determine the strategies that were associated with good adherence.Results: The final analyses included 671 participants (mean age 40.2 years; 54.3% males. The valid response rate was 96.9%; 186 (27.7% participants were classified as non-adherent, the mean adherence rate being 86.1% (standard deviation [SD] 17.9. Seven strategies that patients employ to facilitate adherence were identified, the

  16. Noninvasive detection of macrophages in atherosclerotic lesions by computed tomography enhanced with PEGylated gold nanoparticles

    Directory of Open Access Journals (Sweden)

    Qin J

    2014-12-01

    Full Text Available Jinbao Qin,1,* Chen Peng,2,* Binghui Zhao,2,* Kaichuang Ye,1 Fukang Yuan,1 Zhiyou Peng,1 Xinrui Yang,1 Lijia Huang,1 Mier Jiang,1 Qinghua Zhao,3 Guangyu Tang,2 Xinwu Lu1,4 1Department of Vascular Surgery, Shanghai Ninth People’s Hospital Affiliated to Shanghai JiaoTong University, School of Medicine; 2Department of Radiology, Shanghai Tenth People’s Hospital Affiliated to Tongji University, School of Medicine; 3Department of Orthopaedics, Shanghai First People’s Hospital, School of Medicine, Shanghai Jiao Tong University; 4Vascular Center of Shanghai JiaoTong University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Macrophages are becoming increasingly significant in the progression of atherosclerosis (AS. Molecular imaging of macrophages may improve the detection and characterization of AS. In this study, dendrimer-entrapped gold nanoparticles (Au DENPs with polyethylene glycol (PEG and fluorescein isothiocyanate (FI coatings were designed, tested, and applied as contrast agents for the enhanced computed tomography (CT imaging of macrophages in atherosclerotic lesions. Cell counting kit-8 assay, fluorescence microscopy, silver staining, and transmission electron microscopy revealed that the FI-functionalized Au DENPs are noncytotoxic at high concentrations (3.0 µM and can be efficiently taken up by murine macrophages in vitro. These nanoparticles were administered to apolipoprotein E knockout mice as AS models, which demonstrated that the macrophage burden in atherosclerotic areas can be tracked noninvasively and dynamically three-dimensionally in live animals using micro-CT. Our findings suggest that the designed PEGylated gold nanoparticles are promising biocompatible nanoprobes for the CT imaging of macrophages in atherosclerotic lesions and will provide new insights into the pathophysiology of AS and other concerned inflammatory diseases. Keywords: atherosclerosis, CT, in vivo

  17. Practice of the integrated endocrine system course

    Institute of Scientific and Technical Information of China (English)

    Wen-han MEI; Rong CAI

    2015-01-01

    The integrated curriculum is an important direction of the medical medical education reform under new situation and challenges of medical development.Shanghai Jiao Tong University School of Medicine has implemented the integrated curriculum reform in recent years.The endocrine system course is one of important intergrated courses and integrates relevant contents of multiple disciplines of basic medicine,diagnostics and medical imaging.Various teaching methods are adopted,such as classroom lecture,discussion,problembased learning,experimental lesson and clinical clerkship,etc.The teaching practice is carried on in several aspects:course arrangement,teaching methods,course website construction,teaching team construction and so on.

  18. Radiation ulcers in patients with cancer of the torgue after 252Cf therapy

    International Nuclear Information System (INIS)

    Galantseva, G.F.; Guseva, L.I.; Plichko, V.I.

    1984-01-01

    Interstitial therapy with 252 Cf was conducted for 57 patients with cancer of the tongue. It was established that clinical course of radiation tungue ulcers after interstitial therapy with 252 Cf doesn't differ sufficiently from the course of radiation injuries, occurring after γ-radiation application. Radiation ulcers are often observed in patients after the treatment of recurrent and residual tumors with 252 Cf (in 33% of patients); the ulcers appeared in 15% of cases in patients after the treatment of initial ulcers tumors. Conservative treatment provide the cure of radiation tongUe ulcers after interstitial therapy with 252 Cf

  19. KONVERSI ENERGI BIOMASSA KOTORAN SAPI MELALUI RANCANGAN BIODIGESTER UNTUK RUMAH TANGGA

    Directory of Open Access Journals (Sweden)

    I Gede Bawa Susana

    2017-11-01

    Full Text Available Biomassa kotoran sapi mengandung energi berupa gas metan yang dapat digunakan sebagai bahan bakar. Pengolahan biomassa kotoran sapi menjadi bahan bakar dilakukan melalui proses konversi energi dalam suatu biodigester. Biodigester dibuat untuk kebutuhan rumah tangga dengan kapasitas 0,5997 m3 untuk waktu penyimpanan 30 hari.  Masyarakat yang memelihara sapi 2-3 ekor dapat menggunakan biodigester tipe plastik dan fixed dome dengan kapasitas tong plastik 250 liter. Hasil pengujian menunjukkan bahwa konversi energi biomassa kotoran sapi dapat digunakan sebagai sumber energi pada kompor.

  20. Effect of irradiation on carbohydrates content

    International Nuclear Information System (INIS)

    Chantharasakul, S.

    1971-01-01

    Effect of gamma radiation on vitamin C and total acidity contents of Hom Tong banana was described. There was a slight decrease in vitamin C contents in both irradiated and non-irradiated banana during storage. No difference was detected in term of vitamin C contents between irradiated and non-irradiated banana at any storage time. The total acidity of the banana increased with increasing time of storage owing to the ripening effect of the fruit. Higher total acidity content of non-irradiated banana during storage indicated the faster rate of ripening of the fruit

  1. Oligosaccharide binding to barley alpha-amylase 1

    DEFF Research Database (Denmark)

    Robert, X.; Haser, R.; Mori, H.

    2005-01-01

    Enzymatic subsite mapping earlier predicted 10 binding subsites in the active site substrate binding cleft of barley alpha-amylase isozymes. The three-dimensional structures of the oligosaccharide complexes with barley alpha-amylase isozyme 1 (AMY1) described here give for the first time a thorough...... in barley alpha-amylase isozyme 2 (AMY2), and the sugar binding modes are compared between the two isozymes. The "sugar tongs" surface binding site discovered in the AMY1-thio-DP4 complex is confirmed in the present work. A site that putatively serves as an entrance for the substrate to the active site...

  2. Numerical simulation of multi-phase phenomena in IVR related processes

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Xu [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Bereich Innovative Reaktorsysteme; Shanghai Jiao Tong Univ. (China). School of Nuclear Science and Engineering

    2016-05-15

    IVR (in-vessel retention) is one of the severe accident mitigation measures, which is widely applied in the advanced light water reactors (LWRs) such as KERENA of AREVA, AP1000 of Westinghouse and CAP1400 of SNPTC, and attracts extensive interests of the German and Chinese nuclear scientists. The ultimate target of IVR is to keep the core melt inside the reactor pressure vessel (RPV) and to provide cooling capability via water flowing outside the RPV, the so called external reactor vessel cooling (ERVC). This paper summarizes some activities ongoing in both KIT and SJTU (Shanghai Jiao Tong University) with a few results examples.

  3. The influence of gamma irradiation on shelf-life extension of banana

    International Nuclear Information System (INIS)

    Tiravat, K.

    1971-01-01

    Effect of various doses of gamma radiation on shelf-life extension of Hom Tong banana stored at 17 0 C, 20 0 C, and 23 0 C was described. Irradiated banana stored at 20 0 C and 23 0 C did not show any retardation in ripening. Doses from 20-40 Krad appeared to delay ripening of the banana stored at 17 0 C for 3-5 days. No significant difference in weight losses between irradiated and non-irradiated banana was detected during storage

  4. Conventional Prompt Global Strike: Capabilities Today While Planning for Tomorrow

    Science.gov (United States)

    2012-03-19

    I hOu< pet tesponse, ll’ldud;ng tho trno lOt tevio-•,ng instructions, s<>arc/1Jng oxi•tong data sources, gathenng and mai"tain•ng the data needeo...are politically sensitive. 3. The ability to destroy both a traditionally constructed brick and mortar building, and a deeply buried underground...seconds. This technology is setting the foundation for hypersonic application ”17 and could power a hypersonic CPGS delivery vehicle. NASA describes a

  5. Extension to linear dynamics for hybrid stress finite element formulation based on additional displacements

    Science.gov (United States)

    Sumihara, K.

    Based upon legitimate variational principles, one microscopic-macroscopic finite element formulation for linear dynamics is presented by Hybrid Stress Finite Element Method. The microscopic application of Geometric Perturbation introduced by Pian and the introduction of infinitesimal limit core element (Baby Element) have been consistently combined according to the flexible and inherent interpretation of the legitimate variational principles initially originated by Pian and Tong. The conceptual development based upon Hybrid Finite Element Method is extended to linear dynamics with the introduction of physically meaningful higher modes.

  6. Non-linear mixed-effects pharmacokinetic/pharmacodynamic modelling in NLME using differential equations

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Agersø, Henrik; Madsen, Henrik

    2004-01-01

    The standard software for non-linear mixed-effect analysis of pharmacokinetic/phar-macodynamic (PK/PD) data is NONMEM while the non-linear mixed-effects package NLME is an alternative as tong as the models are fairly simple. We present the nlmeODE package which combines the ordinary differential...... equation (ODE) solver package odesolve and the non-Linear mixed effects package NLME thereby enabling the analysis of complicated systems of ODEs by non-linear mixed-effects modelling. The pharmacokinetics of the anti-asthmatic drug theophylline is used to illustrate the applicability of the nlme...

  7. Femtosecond Laser Microstructuring and Chalcogen Inclusion in Silicon

    Science.gov (United States)

    2011-02-12

    photodetectors. The authors would like to acknowledge Dr. Hao Chen, Ariane E. Beck , Dr. Shuling Wang, and Dr. Gauri V. Karve for helpful discussions. This...2002. 3Z. Huang, J. Oh, and J. C. Campbell, Appl. Phys. Lett. 85, 2386 2004. 4Z. Huang, N. Kong, X. Guo, N. Duan, M. Liu, A. L. Beck , S. K...surfaces microstructured in air," Appl. Phys. Lett. 81, 1999-2001 (2002) [doi:10.1063/1.1504868]. [49] S. Tong, X. N. Liu, T. Gao, X. M. Baa , Y

  8. A delayed diagnosis of unsuspected retinoblastoma in an in vitro fertilisation infant with retinopathy of prematurity

    Institute of Scientific and Technical Information of China (English)

    Tian Tian; Xun-Da Ji; Qi Zhang; Jie Peng; Pei-Quan Zhao

    2016-01-01

    Dear Editor,Iam Dr.Tian Tian,from the Department of Ophthalmology,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai,China.I write to present a rare case report of a delayed diagnosis of unsuspected retinoblastoma(RB)in an in vitro fertilisation(IVF)infant with retinopathy of prematurity.The simultaneous presentation of RB and prematurity of retinopathy(ROP)in an IVF infant is very rare.The relationship between RB and IVF is still indeterminate and mechanisms that lead to ocular or systemic abnormalities

  9. Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology

    OpenAIRE

    Ruan, Jing; Shen,; Wang ,Z; Ji,; Song,; Wang,; Liu,Bao-Liang; Li,; Cui,Daxiang

    2011-01-01

    Jing Ruan1,*, Jie Shen2,*, Zheng Wang2, Jiajia Ji1, Hua Song1, Kan Wang1, Bin Liu1, Jinhui Li2, Daxiang Cui11Department of Bio-Nano Science and Engineering, Key Laboratory for Thin Film and Microfabrication Technology of the Ministry of Education, National Key Laboratory of Micro/Nano Fabrication Technology, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Shanghai Institute of Digestive Diseases, Shanghai...

  10. Teaching Earth Sciences as an interdisciplinary subject: Novel module design involving research literature

    Science.gov (United States)

    Tong, Vincent C. H.

    2010-05-01

    The study of Earth Sciences requires an interdisciplinary approach as it involves understanding scientific knowledge originating from a wide spectrum of research areas. Not only does it include subjects ranging from, for instance, hydrogeology to deep crustal seismology and from climate science to oceanography, but it also has many direct applications in closely related disciplines such as environmental engineering and natural resources management. While research crossing traditional disciplinary boundaries in geosciences is becoming increasingly common, there is only limited integration of interdisciplinary research in the teaching of the subject. Given that the transition from undergraduate education based on subject modules to postgraduate interdisciplinary research is never easy, such integration is a highly desirable pedagogical approach at both undergraduate and postgraduate levels. My presentation is based on a recent teaching project involving novel design of an undergraduate course. The course is implemented in order to address the synergy between research and teaching (Tong, 2009). This project has been shown to be effective and successful in teaching geosciences undergraduates at the University of London. The module consists of studying core geophysical principles and linking them directly to a selection of recently published research papers in a wide range of interdisciplinary applications. Research reviewing and reporting techniques are systematically developed, practised and fully integrated into teaching of the core scientific theories. A fully-aligned assignment with a feedback website invites the students to reflect on the scientific knowledge and the study skills related to research literature they have acquired in the course. This teaching project has been recognized by a teaching award (http://www.clpd.bbk.ac.uk/staff/BETA). In this presentation, I will discuss how undergraduate teaching with a focus on research literature in Earth Sciences can

  11. Status analysis of Chinese standards on enclosure equipment and proposed countermeasures

    International Nuclear Information System (INIS)

    Wu Luping

    1998-12-01

    Enclosure equipment, such as glove box, tong box etc., is an important kind of equipment for nuclear industry and nuclear scientific research. The status of the establishment and implementation of Chinese standards on enclosure equipment is briefly described. Some problems and deficiency existing in these standards are pointed out. The ISO standard projects on containment enclosures as well as their present progress situations are introduced. The measure for updating Chinese standards on enclosure equipment in accordance with the principle of adopting international standards are recommended. Some issues which should be taken into account in adopting ISO standards on containment enclosures are also discussed

  12. ML 3.1 developer's guide.

    Energy Technology Data Exchange (ETDEWEB)

    Sala, Marzio; Hu, Jonathan Joseph (Sandia National Laboratories, Livermore, CA); Tuminaro, Raymond Stephen (Sandia National Laboratories, Livermore, CA)

    2004-05-01

    ML development was started in 1997 by Ray Tuminaro and Charles Tong. Currently, there are several full- and part-time developers. The kernel of ML is written in ANSI C, and there is a rich C++ interface for Trilinos users and developers. ML can be customized to run geometric and algebraic multigrid; it can solve a scalar or a vector equation (with constant number of equations per grid node), and it can solve a form of Maxwell's equations. For a general introduction to ML and its applications, we refer to the Users Guide [SHT04], and to the ML web site, http://software.sandia.gov/ml.

  13. 507 mechanical movements mechanisms and devices

    CERN Document Server

    Brown, Henry T

    2005-01-01

    Epicyclic trains, oblique rollers, trip hammers, and lazy-tongs are among the ingenious mechanisms defined and illustrated in this intriguing collection. Spanning the first century of the Industrial Revolution, this 1868 compilation features simplified, concise illustrations of the mechanisms used in hydraulics, steam engines, pneumatics, presses, horologes, and scores of other machines.The movements of each of the 507 mechanisms are depicted in drawings on the left-hand page, and the facing page presents a brief description of the item's use and operation. Ranging from simple to intricately c

  14. Areeni aasta albumid 2004

    Index Scriptorium Estoniae

    2004-01-01

    Heliplaatidest: Franz Ferdinand "Franz Ferdinand", Toe Tag "Legendaarne", The Libertines "The Libertines ", Morrissey "You Are The Qarry", The Streets "A Grand Don't Come For Free", Kalm "Generalissimus Kalm", Brian Wilson "Smile", Madvillain "Madvillainy", Scissor Sisters "Scissor Sisters", Gary Wilson "Mary Had A Brown Hair", Animal Collective "Sung Tongs", Keane "Hopes And Fears", Todd Rundgren "Liars", Nick Cave & The Bad Seeds "Abbatoir Blues/The Lyre of Orpheus", Mylo "Destroy Rock'n'Roll", Devendra Banhart "Rejoicing In The Hands", Stefani "Love Angel Music Baby", Björk "Medulla", Moodymann "Black Mahogani"

  15. Optimization of fuel cells for BWR based in Tabu modified search; Optimizacion de celdas de combustible para BWR basada en busqueda Tabu modificada

    Energy Technology Data Exchange (ETDEWEB)

    Martin del Campo M, C.; Francois L, J.L. [Facultad de Ingenieria, UNAM, Laboratorio de Analisis en Ingenieria de Reactores Nucleares, Paseo Cuauhnahuac 8532, 62550 Jiutepec, Morelos (Mexico); Palomera P, M.A. [Facultad de Ingenieria, UNAM, Posgrado en Ingenieria en Computacion, Circuito exterior s/n, Ciudad Universitaria, Mexico, D.F. (Mexico)]. e-mail: cmcm@fi-b.unam.mx

    2004-07-01

    The advances in the development of a computational system for the design and optimization of cells for assemble of fuel of Boiling Water Reactors (BWR) are presented. The method of optimization is based on the technique of Tabu Search (Tabu Search, TS) implemented in progressive stages designed to accelerate the search and to reduce the time used in the process of optimization. It was programed an algorithm to create the first solution. Also for to diversify the generation of random numbers, required by the technical TS, it was used the Makoto Matsumoto function obtaining excellent results. The objective function has been coded in such a way that can adapt to optimize different parameters like they can be the enrichment average or the peak factor of radial power. The neutronic evaluation of the cells is carried out in a fine way by means of the HELIOS simulator. In the work the main characteristics of the system are described and an application example is presented to the design of a cell of 10x10 bars of fuel with 10 different enrichment compositions and gadolinium content. (Author)

  16. Lens dislocation has a possible relationship with laser iridotomy

    Directory of Open Access Journals (Sweden)

    Mutoh T

    2012-12-01

    Full Text Available Tetsuya Mutoh,1,2 Kevin F Barrette,2 Yukihiro Matsumoto,1 Makoto Chikuda11Department of Ophthalmology, Dokkyo Medical University Koshigaya Hospital, Koshigaya City, Saitama, Japan; 2Department of Ophthalmology, Boston University School of Medicine, Boston, MA, USAAbstract: We report our recent experience of four eyes with spontaneous lens dislocation in four patients with no history of trauma or any systemic disease associated with zonular dialysis. Lens dislocation developed with 0.5 to 6 months following laser iridotomy. All patients were male and two eyes were complicated with acute primary angle closure glaucoma preoperatively. Case 1 showed bilateral lens dislocation, while cases 2 and 3 involved unilateral lens dislocation. Cases 2 and 3 showed lenses completely dislocated into the vitreous cavity. All cases needed lens removal and scleral fixation of intraocular lenses. Final visual acuity was 1.2 in all cases. We suspect that laser iridotomy may induce localized zonular dialysis that results in progressive zonular weakness, leading to lens dislocation.Keywords: lens dislocation, laser iridotomy, primary angle closure glaucoma

  17. Adherence ability of Staphylococcus epidermidis on prosthetic biomaterials: an in vitro study

    Directory of Open Access Journals (Sweden)

    Shida T

    2013-10-01

    Full Text Available Takayuki Shida,1 Hironobu Koseki,1 Itaru Yoda,1 Hidehiko Horiuchi,1 Hideyuki Sakoda,2 Makoto Osaki11Department of Orthopedic Surgery, Graduate School of Medicine, Nagasaki University, Nagasaki, Japan; 2Division of Medical Devices, National Institute of Health Sciences, Tokyo, JapanAbstract: Bacterial adhesion to the surface of biomaterials is an essential step in the pathogenesis of implant-related infections. In this in vitro research, we evaluated the ability of Staphylococcus epidermidis to adhere to the surface of solid biomaterials, including oxidized zirconium-niobium alloy (Oxinium, cobalt-chromium-molybdenum alloy, titanium alloy, commercially pure titanium, and stainless steel, and performed a biomaterial-to-biomaterial comparison. The test specimens were physically analyzed to quantitatively determine the viable adherent density of the S. epidermidis strain RP62A (American Type Culture Collection [ATCC] 35984. Field emission scanning electron microscope and laser microscope examination revealed a featureless, smooth surface in all specimens (average roughness <10 nm. The amounts of S. epidermidis that adhered to the biomaterial were significantly lower for Oxinium and the cobalt-chromium-molybdenum alloy than for commercially pure titanium. These results suggest that Oxinium and cobalt-chromium-molybdenum alloy are less susceptible to bacterial adherence and are less inclined to infection than other materials of a similar degree of smoothness.Keyword: bacterial adhesion, implant, infection, surface character

  18. A case of cholestatic hepatitis associated with histologic features of acute cholangitis

    Directory of Open Access Journals (Sweden)

    Takeuchi H

    2011-11-01

    Full Text Available Hajime Takeuchi1, Toru Kaneko1, Toshikazu Otsuka1, Kumiko Tahara1, Tadashi Motoori2, Makoto Ohbu3, Masaya Oda4, Hiroaki Yokomori11Department of Internal Medicine; 2Division of Pathology, Kitasato Medical Center Hospital, Kitasato University, Saitama; 3Department of Pathology, School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa; 4Department of Internal Medicine, Saitama Social Insurance Hospital, Saitama; 5Organized Center of Clinical Medicine, International University of Health and Welfare, Sanno Hospital, Tokyo, JapanAbstract: This report describes a case showing histologic features of acute cholangitis with an over-the-counter drug. A 48-year-old woman was diagnosed with general malaise and progressive jaundice. A thorough review of her medical history revealed that the patient had taken an over-the-counter drug, Pabron Gold®, which she had used previously, that may have caused liver injury. Laboratory investigations revealed jaundice and liver dysfunction. Endoscopic retrograde cholangiography detected no extrahepatic biliary duct dilatation or stones. Liver biopsy indicated acute cholangitis involving neutrophils and eosinophils. Electron microscopy revealed fragmented nuclei, indicating that the degenerative bile duct-related epithelial cells were in an apoptotic process.Keywords: liver injury, over-the-counter drug, histologic features, acute cholangitis, electron microscopy, Pabron Gold

  19. Four cases of endophthalmitis after 25-gauge pars plana vitrectomy

    Directory of Open Access Journals (Sweden)

    Mutoh T

    2012-08-01

    Full Text Available Tetsuya Mutoh, Koji Kadoya, Makoto ChikudaDepartment of Ophthalmology, Dokkyo Medical University Koshigaya Hospital, Koshigaya, Saitama, JapanAbstract: We report our recent experience with four cases of endophthalmitis (one male, three females after 25-gauge pars plana vitrectomy (PPV. One was a case of persistent cystoid macular edema caused by branch retinal vein occlusion, whereas the remaining three were cases of epiretinal membrane. Preoperative antibiotics before the first PPV procedure were not administered in three of the four cases. Endophthalmitis occurred 2–4 days after the first procedure in all cases, for which ceftazidime 2.0 mg/0.1 mL and vancomycin 1.0 mg/0.1 mL were injected into the vitreous cavity. This was followed by emergent 20-gauge PPV and intraocular lens removal using an infusion fluid containing ceftazidime and vancomycin. After the second PPV procedure, progress was good in three cases while retinal detachment occurred in the remaining case one month after surgery; this case required a third PPV procedure. Final best-corrected visual acuity ranged from 20/100 to 20/25 for the four cases. Bacterial cultures were negative after the second PPV procedure in all cases. In conclusion, postoperative endophthalmitis occurred in four of 502 cases (0.80% that underwent 25-gauge PPV at our hospital. It is important to minimize the incidence of endophthalmitis after 25-gauge PPV.Keywords: 25-gauge pars plana vitrectomy, endophthalmitis, incidence

  20. Optimization of fuel cells for BWR based in Tabu modified search

    International Nuclear Information System (INIS)

    Martin del Campo M, C.; Francois L, J.L.; Palomera P, M.A.

    2004-01-01

    The advances in the development of a computational system for the design and optimization of cells for assemble of fuel of Boiling Water Reactors (BWR) are presented. The method of optimization is based on the technique of Tabu Search (Tabu Search, TS) implemented in progressive stages designed to accelerate the search and to reduce the time used in the process of optimization. It was programed an algorithm to create the first solution. Also for to diversify the generation of random numbers, required by the technical TS, it was used the Makoto Matsumoto function obtaining excellent results. The objective function has been coded in such a way that can adapt to optimize different parameters like they can be the enrichment average or the peak factor of radial power. The neutronic evaluation of the cells is carried out in a fine way by means of the HELIOS simulator. In the work the main characteristics of the system are described and an application example is presented to the design of a cell of 10x10 bars of fuel with 10 different enrichment compositions and gadolinium content. (Author)

  1. Case of bilateral complete posterior dislocation of lens caused by elder abuse

    Directory of Open Access Journals (Sweden)

    Matsumoto Y

    2012-02-01

    Full Text Available Tetsuya Mutoh1,2, Thomas Tien2, Megumi Horie1, Yukihiro Matsumoto1, Makoto Chikuda11Department of Ophthalmology, Dokkyo Medical University Koshigaya Hospital, Koshigaya, Saitama, Japan; 2Department of Ophthalmology, Boston University School of Medicine, Boston, MA, USAAbstract: We report a case of bilateral complete dislocation of lenses into the vitreous cavities due to elder abuse in a patient with senile dementia. According to the patient’s son, bilateral complete lens dislocation occurred after he hit his father in the head with socks in order to control his violent behavior. Although the patient was taken to our ophthalmological ward for a planned vitrectomy, restlessness and inability to remain in his room during the night led to his leaving the hospital. The patient has not returned but did receive a vitrectomy at another clinic. While the number of patients with senile dementia has dramatically increased, no specific remedy is currently available. When treating medical concerns of seniors with unknown backgrounds, elder abuse needs to be considered as a potential cause of such injuries.Keywords: bilateral dislocation of lenses, elder abuse, senile dementia, vitrectomy

  2. Report on survey in fiscal 2000 on the survey on succession of history of industrial technologies. Survey edition of originality and creativity of electric and electronic technologies in Japan; 2000 nendo sangyo gijutsu rekishi keisho chosa hokokusho. Kokunai sangyo no denki denshi gijutsu no dokusosei to sozosei no chosahen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    In order to clarify the innovation process of industrial technologies in Japan and the originality and creativity seen in that process to serve for the future development, hearing surveys have been performed. The persons being the hearing objects are Mr. Koichi Oshima who has researched the series capacitors for power transmission cables, Mr. Makoto Osatake who has researched the distortion in frequency modulation, and Mr. Hisao Oka who has researched the destruction phenomena in rectifier elements of power semiconductors. Mr. Hiroshi Inose and Mr. Toichiro Koike who have accepted the hearing survey were represented by the mourning statements due to their sudden death. The items of the questions in the hearing survey included: their home background, why have they studied electricity area specially?, determination criteria when they were forced to make a serious selection and the results thereof, examples of successes and failures and the age background, breakthrough points in the success cases, what they want to convey to future generations from their achievements, what they wished if they have done, methods of conveying the technologies, persons whom they respect as their teachers, existence of persons who have given them protection, sources of passion and motivation that supported the research life, and the principles toward the research. (NEDO)

  3. Injuries and disorders among young ice skaters: relationship with generalized joint laxity and tightness

    Directory of Open Access Journals (Sweden)

    Okamura S

    2014-08-01

    Full Text Available Shinobu Okamura,1 Naoki Wada,1 Masayuki Tazawa,1 Makoto Sohmiya,1 Yoko Ibe,1 Toru Shimizu,1 Shigeru Usuda,2 Kenji Shirakura1 1Department of Rehabilitation Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan; 2Department of Physical Therapy, Gunma University School of Health Science, Maebashi, Gunma, Japan Abstract: This study retrospectively investigated 192 teenage speed and figure skaters with prior injuries documented by an athletes’ questionnaire, who underwent a physical examination to assess their muscle tightness and generalized joint laxity. In all athletes, the degree of muscle tightness and joint laxity were measured by a standardized physical examination. A descriptive report of the types of injuries showed a predominance of fractures, ligament injuries, enthesitis, and lower back pain. Approximately 5% of all skaters tested positive for tightness, while 25.8% of figure skaters and 15.2% of speed skaters had generalized ligamentous laxity. Statistical testing showed an association between ankle sprains and muscle tightness, and an association between knee enthesitis and muscle tightness in skating athletes. There was also an association between lower back pain and generalized joint laxity, which held true only for the male skaters. Keywords: sports injury, skating, junior athlete, tightness, joint laxity, medical checkup

  4. NEDO Forum 2001. Session on IT (Opening the door to research and development of the future); NEDO Forum 2001. IT session (kenkyu kaihatsu no mirai wo hiraku)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-09-20

    The presentations made at the above-said session on IT (information technology) of the NEDO (New Energy and Industrial Technology Development Organization) forum held in Tokyo on September 20, 2001, are collected in this report. Visiting Professor Emeritus Makoto Kikuchi of Tokai University in his lecture entitled 'Message to young researchers' cited lessons from the history of semiconductor research and development and stressed the importance of management and of the vitality to be produced by tension at the working place. He predicted that in the future the merit that technologies would present would be valued higher than the development of technologies and that software programs would grow in relative importance. Professor Sakurai of Institute of Industrial Science, University of Tokyo, in his lecture entitled 'What people want from research and development in the future' dealt with propensity for application, coordination of different technologies, and the importance of the internationalization of persons of talent. Chief Engineer Murakami of Sumitomo Electric Industries Ltd. spoke in his lecture, entitled 'Research and development strategy in business corporations,' about corporate consciousness of research and development in Japan, development and use of new scoring methods, and one-sigma management. (NEDO)

  5. Lévy matters V functionals of Lévy processes

    CERN Document Server

    Andersen, Lars Nørvang; Aurzada, Frank; Glynn, Peter W; Maejima, Makoto; Pihlsgård, Mats; Simon, Thomas

    2015-01-01

    This three-chapter volume concerns the distributions of certain functionals of Lévy processes. The first chapter, by Makoto Maejima, surveys representations of the main sub-classes of infinitesimal distributions in terms of mappings of certain Lévy processes via stochastic integration. The second chapter, by Lars Nørvang Andersen, Søren Asmussen, Peter W. Glynn and Mats Pihlsgård, concerns Lévy processes reflected at two barriers, where reflection is formulated à la Skorokhod. These processes can be used to model systems with a finite capacity, which is crucial in many real life situations, a most important quantity being the overflow or the loss occurring at the upper barrier.  If a process is killed when crossing the boundary, a natural question concerns its lifetime. Deep formulas from fluctuation theory are the key to many classical results, which are reviewed in the third chapter by Frank Aurzada and Thomas Simon. The main part, however, discusses recent advances and developments in the setting w...

  6. BRAIN vol. 4 (2013, issues 1-4, first 4 pages

    Directory of Open Access Journals (Sweden)

    Bogdan Patrut

    2013-10-01

    Full Text Available TABLE OF CONTENTS Sections BRAINStorming and BRAINovations 1. Evolving Spiking Neural Networks for Control of Artificial Creatures 5Arash Ahmadi 2. Artificial Neuron Modelling Based on Wave Shape 20Kieran Greer 3. Brain-Like Artificial Intelligence for Automation – Foundations, Concepts andImplementation Examples 26Rosemarie Velik 4. Performance Analysis of Unsupervised Clustering Methods for Brain Tumor Segmentation 55Tushar H Jaware and Dr. K B Khanchandani 5. High Performance Data mining by Genetic Neural Network 60Dadmehr Rahbari 6. Isomorphism Between Estes’ Stimulus Fluctuation Model and a Physical-Chemical System 71Makoto Yamaguchi 7. Intelligent Continuous Double Auction method For Service Allocation in Cloud Computing 74Nima Farajian, Kamran Zamanifar 8. An Enhancement Over Texture Feature Based Multiclass Image Classification UnderUnknown Noise 84Ajay Kumar Singh, V P Shukla, Shamik Tiwari and S R Biradar 9. Suicide: Neurochemical Approaches 97Ritabrata Banerjee, Anup K. Ghosh, Balaram Ghosh, Somnath Bhattacharya and Amal C. Mondal 10. L1 Transfer in Post-Verbal Preposition: An Inter-level Comparison 125Samira Mollaei, Ali Jahangard and Hemaseh Bagheri Section BRAINotes 11. Looking for Oriental fundamentals Fuzzy Logic 141Ángel Garrido and Piedad Yuste Instructions for authors 146

  7. Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine

    Directory of Open Access Journals (Sweden)

    Hong X

    2013-09-01

    Full Text Available Xiaoyun Hong,1,2,* Liangming Wei,3,* Fei Wu,2,* Zaozhan Wu,2 Lizhu Chen,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital, Shanghai, People's Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, Shanghai, People's Republic of China; 3Research Institute of Micro/Nano Science and Technology, Shanghai JiaoTong University, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: Microneedles were first conceptualized for drug delivery many decades ago, overcoming the shortages and preserving the advantages of hypodermic needle and conventional transdermal drug-delivery systems to some extent. Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods. Finally, this review puts forward some perspectives that require further investigation. Keywords: microneedle, dissolving, biodegradable, sustained release

  8. The History of East Asia as Newly Recognized from the Perspective of Korean Historians

    Directory of Open Access Journals (Sweden)

    Cho Young-hun

    2017-03-01

    Full Text Available Miyazima Hiroshi and Bae Hang-seob, eds. Tong Asia nŭn myŏt si inga?: Tong Asia-sa ŭi saeroun ihae rŭl ch’ajasŏ 동아시아는 몇 시인가?: 동아시아사의 새로운 이해를 찾아서 [What time is East Asia? In search of a new understanding of East Asian history]. Seoul: Nŏmŏ puksŭ, 2015. ISBN: 9788994606392. The Eurocentrism and modern-centrism that have established themselves as the predominant discourses of historians may need to be further pushed aside by new discourses. Sinocentrism, decentralism, multiple modernities, alternative modernity—these are just a few of the candidates. No one knows what the dominant discourse is going to be down the road. Fourteen authors, including editors Miyazima Hiroshi and Bae Hang-seob, contributed to the collection What Time Is East Asia? In Search of a New Understanding of East Asian History in 2015. This book presents a new historical discourse that emerged in Korea as a critique of Eurocentrism and modern-centrism. The title refers to a question posed by Alexander Woodside in his 2006 book, Lost Modernities, and is meant to suggest that the historical experience of East Asia cannot be grasped by historical perspectives based on Eurocentrism...

  9. Nonopioid anesthesia for awake craniotomy: a case report.

    Science.gov (United States)

    Wolff, Diane L; Naruse, Robert; Gold, Michele

    2010-02-01

    Awake craniotomy is becoming more popular as a neurosurgical technique that allows for increased tumor resection and decreased postoperative neurologic morbidity. This technique, however, presents many challenges to both the neurosurgeon and anesthetist. An ASA class II, 37-year-old man with recurrent oligodendroglioma presented for repeated craniotomy. Prior craniotomy under general anesthesia resulted in residual neurologic deficits. An awake craniotomy was planned to allow for intraoperative testing for maximum tumor resection and avoidance of neurologic morbidity. The patient was sedated with propofol, and bupivacaine was infiltrated for placement of Mayfield tongs and skin incision. Following exposure of brain tissue, propofol infusion was discontinued to allow for patient cooperation during the procedure. Speech, motor, and sensory testing occurred during tumor resection until resection stopped after onset of weakness in the right arm. The propofol infusion was resumed while the cranium was closed and Mayfield tongs removed. The patient was awake, alert, oriented, and able to move all extremities but had residual weakness in the right forearm. Awake craniotomy requires appropriate patient selection, knowledge of the surgeon's skill, and a thorough anesthesia plan. This case report discusses the clinical and anesthetic management for awake craniotomy and reviews the literature.

  10. Music therapy to promote prosocial behaviors in aggressive adolescent boys--a pilot study.

    Science.gov (United States)

    Rickson, Daphne J; Watkins, William G

    2003-01-01

    This pilot study was undertaken to investigate whether music therapy is effective in promoting prosocial behaviors in aggressive adolescent boys who have social, emotional, and learning difficulties. Fifteen subjects (aged 11-15 years), enrolled at a special residential school in New Zealand, were randomly assigned to music therapy treatment groups (n = 6, n = 5), and a waitlist control group (n = 4). Examination of demographic data identified differences between groups for diagnosis (p =.044), with Group 1 all having Attention Deficit Hyperactivity Disorder (ADHD), and for age (p =.027), with Group 2 having a mean age 1.38 years older. Measures included parent and teacher versions of the Developmental Behaviour Checklist (DBC-P & DBC-T) (Einfeld & Tonge, 1994; Einfeld, Tonge, & Parmenter, 1998). While no definite treatment effects could be detected, results suggest that a music therapy program promoting autonomy and creativity may help adolescents to interact more appropriately with others in a residential villa setting, but might also lead to a temporary mild increase in disruptive behavior in the classroom. A more highly structured program and smaller group numbers may be advantageous for boys who have ADHD.

  11. Getting to the bottom: Tesco's Casing Running System improves speed, efficiency and safety

    Energy Technology Data Exchange (ETDEWEB)

    Eaton, S.

    2004-02-01

    Tesco Corporation's newly-introduced Casing Running System that is gaining rapid mainstream acceptance in the drilling industry is discussed. The popularity of the system is due not only to its technical advances in conveying casing into the borehole, but also to the increased safety features that it provides drilling operators. While conventional casing operations limit the driller to either rotating or reciprocating the string, the Tesco system permits simultaneously to rotate, reciprocate and circulate the casing string. From the point of view of safety, the Tesco Casing Running System eliminates the need for the roughnecks to harness up in 'riding belts', to climb up the derrick to guide casing pipe and insert hoses into joints for mud circulation. Travelling rig elevators and power tongs, normally required to make joint connections, are also made superfluous by the Tesco System. The bulk of the paper is devoted to a discussion of design and operating characteristics of the tool and cost comparison with conventional power tongs. 3 photos.

  12. Chinese herbal formula Tongluo Jiunao injection protects against cerebral ischemia by activating neurotrophin 3/tropomyosin-related kinase C pathway

    Directory of Open Access Journals (Sweden)

    Peiman Alesheikh

    2015-01-01

    Full Text Available The Chinese herbal formula Tongluo Jiunao, containing the active components Panax notoginseng and Gardenia jasminoides, has recently been patented and is in use clinically. It is known to be neuroprotective in cerebral ischemia, but the underlying pathway remains poorly understood. In the present study, we established a rat model of cerebral ischemia by occlusion of the middle cerebral artery, and administered Tongluo Jiunao, a positive control (Xuesai Tong, containing Panax notoginseng or saline intraperitoneally to investigate the pathway involved in the action of Tongluo Jiunao injection. 2,3,5-Triphenyltetrazolium chloride (TTC staining showed that the cerebral infarct area was significantly smaller in model rats that received Tongluo Jiunao than in those that received saline. Enzyme-linked immunosorbent assay revealed significantly greater expression of neurotrophin 3 and growth-associated protein 43 in ischemic cerebral tissue, and serum levels of neurotrophin 3, in the Tongluo Jiunao group than in the saline group. The reverse transcription polymerase chain reaction and immunohistochemical staining showed that after treatment with Tongluo Jiunao or Xuesai Tong, tropomyosin-related kinase C gene expression and immunoreactivity were significantly elevated compared with saline, with the greatest expression observed after Tongluo Jiunao treatment. These findings suggest that Tongluo Jiunao injection exerts a neuroprotective effect in rats with cerebral ischemia by activating the neurotrophin 3/tropomyosin-related kinase C pathway.

  13. Antioxidant effects of herbal therapies used by patients with inflammatory bowel disease: an in vitro study.

    Science.gov (United States)

    Langmead, L; Dawson, C; Hawkins, C; Banna, N; Loo, S; Rampton, D S

    2002-02-01

    Herbal remedies used by patients for treatment of inflammatory bowel disease include slippery elm, fenugreek, devil's claw, Mexican yam, tormentil and wei tong ning, a traditional Chinese medicine. Reactive oxygen metabolites produced by inflamed colonic mucosa may be pathogenic. Aminosalicylates (5-ASA) are antioxidant and other such agents could be therapeutic. To assess the antioxidant effects of herbal remedies in cell-free oxidant-generating systems and inflamed human colorectal biopsies. Luminol-enhanced chemiluminescence in a xanthine/xanthine oxidase cell-free system was used to detect superoxide scavenging by herbs and 5-ASA, and fluorimetry to define peroxyl radical scavenging using a phycoerythrin degradation assay. Chemiluminescence was used to detect herbal effects on generation of oxygen radicals by mucosal biopsies from patients with active ulcerative colitis. Like 5-ASA, all herbs, except fenugreek, scavenged superoxide dose-dependently. All materials tested scavenged peroxyl dose-dependently. Oxygen radical release from biopsies was reduced after incubation in all herbs except Mexican yam, and by 5-ASA. All six herbal remedies have antioxidant effects. Fenugreek is not a superoxide scavenger, while Mexican yam did not inhibit radical generation by inflamed biopsies. Slippery elm, fenugreek, devil's claw, tormentil and wei tong ning merit formal evaluation as novel therapies in inflammatory bowel disease.

  14. Clinical Significance of the Champagne Bottle Neck Sign in the Extracranial Carotid Arteries of Patients with Moyamoya Disease.

    Science.gov (United States)

    Yasuda, C; Arakawa, S; Shimogawa, T; Kanazawa, Y; Sayama, T; Haga, S; Morioka, T

    2016-05-26

    The champagne bottle neck sign represents a rapid reduction in the extracranial ICA diameters and is a characteristic feature of Moyamoya disease. However, the clinical significance of the champagne bottle neck sign is unclear. We investigated the relationship between the champagne bottle neck sign and the clinical and hemodynamic stages of Moyamoya disease. We analyzed 14 patients with Moyamoya disease before revascularization (5 men, 9 women; age, 43.2 ± 19.3 years). The ratio of the extracranial ICA and common carotid artery diameters was determined using carotid ultrasonography or cerebral angiography; a ratio of champagne bottle neck sign-positive. The clinical disease stage was determined using the Suzuki angiographic grading system. CBF and cerebral vasoreactivity also were measured. The ICA/common carotid artery ratio (expressed as median [interquartile range]) decreased as the clinical stage advanced (stages I-II, 0.71 [0.60-0.77]; stages III-IV, 0.49 [0.45-0.57]; stages V-VI, 0.38 [0.34-0.47]; P champagne bottle neck sign-positive arteries were classified as Suzuki stage ≥III, 73% were symptomatic, and 89% exhibited reduced cerebral vasoreactivity. In contrast, all champagne bottle neck sign-negative arteries were Suzuki stage ≤III, 67% were asymptomatic, and all showed preserved cerebral vasoreactivity. The champagne bottle neck sign was related to advanced clinical stage, clinical symptoms, and impaired cerebral vasoreactivity. Thus, detection of the champagne bottle neck sign might be useful in determining the clinical and hemodynamic stages of Moyamoya disease. © 2016 American Society of Neuroradiology.

  15. Intra-annual variability in nutrients in the Godavari estuary, India

    Digital Repository Service at National Institute of Oceanography (India)

    Sarma, V.V.S.S.; Prasad, V.R.; Kumar, B.S.K.; Rajeev, K.; Devi, B.M.M.; Reddy, N.P.C.; Sarma, V.V.; DileepKumar, M.

    , and spectrofluorometrically measured (Suzuki and Ishimaru, 1990). The analytical precision for Chl a analysis was ±4%. All these analyses were completed within 12 hours of sampling at the shore-based laboratory set up at Yanam, on the bank of the river. Net community... s -1 ). There was virtually no discharge between January and May due to drying of the river in the upstream (Fig. 2b). The inter-annual variability in the October – November discharge was due to changes in the precipitation pattern in the upstream...

  16. Tandem Reduction/Cyclization of O-Nitrophenyl Propargyl Alcohols-A Novel Synthesis of 2- & 2,4-Disubstituted Quinolines and Application to the Synthesis of Streptonigrin

    Science.gov (United States)

    2008-01-01

    useful quinoline alkaloids from both plant and marine animal sources each year.10-20 N OH OMe OMe Me COOH H2N N O O H2N MeO N N N O O O OH OH OH N...the synthesis of an inhibitor of HMG-CoA (the rate-limiting enzyme in sterol biosynthesis in animals and plants ) was conducted by Suzuki, using a...less commonly identified in the literature. An early example was reported by Pelletier in his synthesis of three monoterpene pheromones (22, 23, and

  17. Biosynthesis of Metal Nanoparticles: Novel Efficient Heterogeneous Nanocatalysts

    Science.gov (United States)

    Palomo, Jose M.; Filice, Marco

    2016-01-01

    This review compiles the most recent advances described in literature on the preparation of noble metal nanoparticles induced by biological entities. The use of different free or substituted carbohydrates, peptides, proteins, microorganisms or plants have been successfully applied as a new green concept in the development of innovative strategies to prepare these nanoparticles as different nanostructures with different forms and sizes. As a second part of this review, the application of their synthetic ability as new heterogonous catalysts has been described in C–C bond-forming reactions (as Suzuki, Heck, cycloaddition or multicomponent), oxidations and dynamic kinetic resolutions. PMID:28335213

  18. Photovoltaic Performance of Polymers Based on Dithienylthienopyrazines Bearing Thermocleavable Benzoate Esters

    DEFF Research Database (Denmark)

    Petersen, Martin Helgesen; Krebs, Frederik C

    2010-01-01

    Thermocleavable low-band-gap polymers based on dithienylthienopyrazines were prepared and copolymerized with different donor units like dialkoxybenzene, fluorene, thiophene, and cyclopentadithiophene (CPDT) using both Stille and Suzuki cross-coupling reactions. In the solid state the band gaps...... are in the range of 1.17−1.37 eV. The polymers were explored as donor materials in bulk heterojunction solar cells together with PCBM as the acceptor material where they were shown to exhibit a photoresponse in the full absorption range up to 900 nm and power conversion efficiencies of up to 1.21% under 1 sun...

  19. Hubungan antara Pola Sidik Bibir dan Jenis Suku Melayu Riau

    Directory of Open Access Journals (Sweden)

    Dedi Afandi

    2017-12-01

    Full Text Available Sidik bibir telah lama digunakan sebagai salah satu metode identifikasi individu.  Penelitian hubungan pola sidik bibir dengan jenis suku belum banyak diteliti, khususnya di Indonesia. Penelitian ini bertujuan mendapatkan hubungan pola sidik bibir antara galur murni suku Melayu Riau dan suku bukan Melayu Riau.Penelitian studi potong lintang dilakukan di Fakultas Kedokteran Universitas Riau antara bulan Juli sampai Agustus tahun 2015.  Sebanyak 160 mahasiswa memenuhi kriteria sampel penelitian dengan metode pengambilan sampel secara acak sederhana.  Kriteria eksklusi adalah mahasiswa Fakultas Kedokteran yang mengalami kelainan anatomi pada bibirnya (labiochisis/ labiopalatochisis, pascatrauma, dan alergi terhadap lipstik. Metode Vahanwal-Nayak-Pagare digunakan untuk mencetak pola sidik bibir. Pola sidik bibir ditetapkan dengan menggunakan klasifikasi Suzuki dan Tsuchihashi pada kedelapan kuadran bibir.  Jenis suku terbanyak adalah suku bukan Melayu Riau 111 (69,4% dibanding dengan galur murni suku Melayu Riau 49(30,6%. Uji statistik menunjukkan hubungan yang signifikan hanya pada kuadran 3 (p = 0,04.  Dapat disimpulkan bahwa pola sidik bibir dapat digunakan untuk metode alternatif identifikasi personal, akan tetapi tidak dapat digunakan untuk membedakan galur murni suku Melayu Riau dengan bukan Melayu Riau pada populasi penelitian. Kata kunci: Klasifikasi Suzuki dan Tsuchihashi, sidik bibir, suku melayu Riau Association between Lip Print Pattern and Riau Malay Ethnics Lip print have long been used as one of the personal identification methods. Studies on the lip print pattern associated with ethnicity has not been widely available, especially in Indonesia. This was a  study aimed to identify association between lip printi patterns and pure strains of Riau Malay and non-Malay Riau. A cross-sectional study was conducted at the Faculty of Medicine, University of Riau, between July to August 2015. A total of 160 students who met the criteria

  20. N=2 current algebra and coset models

    International Nuclear Information System (INIS)

    Hull, C.M.; Spence, B.

    1990-01-01

    The N=2 supersymmetric extension of the Kac-Moody algebra and the corresponding Sugawara construction of the N=2 superconformal algebra are discussed both in components and in N=1 superspace. A formulation of the Kac-Moody algebra and Sugawara construction is given in N=2 superspace in terms of supercurrents satisfying a non-linear chiral constraint. The operator product of two supercurrents includes terms that are non-linear in the supercurrents. The N=2 generalization of the GKO coset construction is then given and the conditions found by Kazama and Suzuki are seen to arise from the non-linearity of the algebra. (orig.)

  1. A general synthesis of C8-arylpurine phosphoramidites.

    Science.gov (United States)

    Vongsutilers, Vorasit; Daft, Jonathan R; Shaughnessy, Kevin H; Gannett, Peter M

    2009-09-02

    A general scheme for the synthesis of C8-arylpurine phosphoramidites has been developed. C8-Arylation of C8-bromo-2'-deoxyguanosine is the key step and has been achieved through the use of a Suzuki coupling. Since the coupling reaction is conducted under aqueous conditions, it is unnecessary to protect and then deprotect the hydroxyl groups, thus saving several steps and improving overall yields. Once the C8-arylgroup is introduced, the glycosidic bond becomes very sensitive to acid catalyzed cleavage. Protection of the amino groups as the corresponding N,N-dimethylformamidine derivative improves stability of the derivatives. Synthetic C8-arylpurines were successfully used to prepare synthetic oligonucleotides.

  2. Identification of an enhancer element of class Pi glutathione S-transferase gene required for expression by a co-planar polychlorinated biphenyl.

    OpenAIRE

    Matsumoto, M; Imagawa, M; Aoki, Y

    1999-01-01

    3,3',4,4',5-Pentachlorobiphenyl (PenCB), one of the most toxic co-planar polychlorinated biphenyl congeners, specifically induces class Pi glutathione S-transferase (GSTP1) as well as cytochrome P-450 1A1 in primary cultured rat liver parenchymal cells [Aoki, Matsumoto and Suzuki (1993) FEBS Lett. 333, 114-118]. However, the 5'-flanking sequence of the GSTP1 gene does not contain a xenobiotic responsive element, to which arylhydrocarbon receptor binds. Using a chloramphenicol acetyltransferas...

  3. Improved calculation of the third virial coefficient of a free anyon gas

    International Nuclear Information System (INIS)

    Law, J.; Khare, A.; Bhaduri, R.K.; Suzuki, A.

    1994-01-01

    For three anyons confined in a harmonic oscillator, only the class of states that interpolates nonlinearly with the statistical parameter contributes to the third virial coefficient of a free anyon gas. Rather than evaluating the full three-body partition function as was done in an earlier publication [J. Law, A. Suzuki, and R. Bhaduri, Phys. Rev. A 46, 4693 (1992)], here only the nonlinear contribution is calculated, thus avoiding delicate cancellations between the irrelevant linear part and the two-body partition function. Our numerical results are consistent with the simple analytical form suggested recently by Myrheim and Olaussen [Phys. Lett. B 299, 267 (1993)

  4. 芥川龍之介の童話『蜘蛛の糸』 : ヨーロッパ人の仏教説話を翻案する試み(松永俊男教授退任記念号)

    OpenAIRE

    小林, 信彦; Nobuhiko, Kobayashi; 桃山学院大学文学部(元)

    2009-01-01

    Paul Carus (1852-1919) wrote a short Buddhist narrative called "The Spider-web" in 1894 and Teitaro Suzuki (鈴木貞太郎 1870-1966) translated it into Japanese in 1898. Ryunosuke Akutagawa (芥川龍之介 1892-1927) adapted it for children in 1918. Entitled "Kumo-no-ito" (蜘蛛の糸 a spider's thread), this adaptation was evaluated highly among Japanese critics and adopted in many schoolbooks. In spite of its high reputation among critics, however, Akutagawa's Kumo-no-ito is not a success as an adapted story. Igno...

  5. Külmavõitu vastane : [talveauto 2014

    Index Scriptorium Estoniae

    2014-01-01

    TM võrdleb: BMW 318d GT A, Citroën C4 Picasso e-HDi 115, Dacia Logan MCV TCe 90, Honda CR-V 1,6 i-DTEC, Kia Carens 1,6 GDI, Lexus IS 300h, Mazda3 Sedan 2,0 Skyactiv-G, Mercedes-Benz CLA 200 BE A, Nissan Note 1,5 dCi, Opel Adam 1,4, Peugeot 308 1,6 THP, Renault Captur TCe 120 EDC, Suzuki SX4 S-Cross 1,6, VVT CVT, Škoda Octavia 1,4 TSI, Toyota Corolla 1,6 Valvematic

  6. Antioxidant study of biaryls synthesized in the presence of Aliquat-336 activated by ultrasound

    Directory of Open Access Journals (Sweden)

    khemais Said

    2016-05-01

    Full Text Available In this work we describe the study of some Suzuki coupling reactions of an aryl halide with arylboronic acids. The reaction yields obtained were increased through sonochemical activation and in the presence of a phase transfer catalyst for a very short period of time. The isolated products obtained are of a high purity. In this context, we propose the reaction mechanisms for these reactions in the presence of a catalyst. Synthesized compounds were screened for theirantioxidant activity with 1,1-diphenyl-2-picrylhydrazyl (DPPH, ferric reducing power (FRP assay and ferrous ion chelating (FIC methods. It was found that Biaryls synthesized compounds showed appreciate antioxidant activity.

  7. A TBA approach to thermal transport in the XXZ Heisenberg model

    Science.gov (United States)

    Zotos, X.

    2017-10-01

    We show that the thermal Drude weight and magnetothermal coefficient of the 1D easy-plane Heisenberg model can be evaluated by an extension of the Bethe ansatz thermodynamics formulation by Takahashi and Suzuki (1972 Prog. Theor. Phys. 48 2187). They have earlier been obtained by the quantum transfer matrix method (Klümper 1999 Z. Phys. B 91 507). Furthermore, this approach can be applied to the study of the far-out of equilibrium energy current generated at the interface between two semi-infinite chains held at different temperatures.

  8. Significance of the Hepatic Artery Anatomy and Radionuclide Flow Data for the Technique and Results of Intra-arterial Infusion Chemotherapy in Patients with Liver Neoplasms

    International Nuclear Information System (INIS)

    Vaicekavicius, E.; Satkevicius, Z.; Kiudelis, J. and others

    2002-01-01

    The aim of this study was to evaluate the impact of different variations of liver vascular anatomy and hemodynamics in achieving the maximum effect of the hepatic artery infusion chemotherapy (HAIC) in patients with primary or metastatic hepatic malignancies. The retrograde analysis of hepatic artery (HA) anatomy and of radionuclide flow data on 23 patients treated by HAIC was performed. The HA anatomy was analysed according to two classification systems: the first one proposed by Michels, which describes 10 variants, and the second one proposed by Suzuki, which describes 3 variants - single, double or multiple HA with 3 subtypes of each variant (celiac, mesenteric and mixed). Additionally, before starting HAIC, 99mTc human macroalbumin was injected through the catheter at a slow rate into the HA of 10 patients with abnormal variants of HA anatomy. Radionuclide testing was performed with the aim to evaluate the subsequent intrahepatic distribution of chemotherapy agents. The intra-arterial regimen of HAIC for all patients consisted of a 5-day infusion of 5-ftorouracil or floxuridine with addition of doxorubicin or cisplatin. Such treatment was repeated every 3-4 weeks 3-6 times for every patient. The typical anatomy of HA branching was seen in 12 (52.2%) patients. The double origin of HA (according to Suzuki's classification) was seen in 9 (39.1%). In 5 (21.7%) of them the right HA was coming out from the superior mesenteric artery. In the remaining 4 (17.4%) patients the left HA was coming out from the left gastric artery. In one patient, multiple HA were observed, and there was no possibility to perform HAIC at all. The preliminary embolization of one of HA was performed in 3 patients with double HA according to Suzuki's classification. Redistribution of hepatic flow through intrahepatic collaterals was achieved in all 3 patients and assessed by radionuclide examination. The aberrant left HA was not embolized in 4 patients, because the metastatic tumours were

  9. Heteroaryl ethers by oxidative palladium catalysis of pyridotriazol-1-yloxy pyrimidines with arylboronic acids.

    Science.gov (United States)

    Bardhan, Sujata; Wacharasindhu, Sumrit; Wan, Zhao-Kui; Mansour, Tarek S

    2009-06-18

    The oxidative palladium-catalyzed cross-coupling of pyrimidines containing pyridotriazol-1-yloxy (OPt) as either a urea or an amide functional group with arylboronic acids in the presence of Cs(2)CO(3) in DME containing 0.6-1.0% H(2)O is described for the preparation of heteroaryl ethers. The bromo substitution in the case of 3-(5-bromo-pyrimidin-2-yloxy)-3H-[1,2,3]triazolo[4,5-b]pyridine 1 could serve as a handle for further elaborations such as Suzuki coupling for attaching varied aryl groups.

  10. A quark-parton description of the deep inelastic scattering processes

    International Nuclear Information System (INIS)

    Bajpai, R.P.

    1977-01-01

    A consistent description of various deep inelastic processes in a quark-parton model is presented. The valence quark probability distribution and the form of core quark probability distribution is fixed from the deep inelastic electroproduction data. Langacker and Suzuki prescription is used to fix the p and n quark core distribution. The differential excitation of quark currents similar to the Harari model of e + e - annihilation process is invoked in deep inelastic electroproduction and neutrino reactions. An effective phenomenological form of the weak currents associated with new quarks and the associated nucleon structure is determined. (author)

  11. Dihydroazulene photoswitch operating in sequential tunneling regime

    DEFF Research Database (Denmark)

    Broman, Søren Lindbæk; Lara-Avila, Samuel; Thisted, Christine Lindbjerg

    2012-01-01

    to electrodes so that the electron transport goes by sequential tunneling. To assure weak coupling, the DHA switching kernel is modified by incorporating p-MeSC6H4 end-groups. Molecules are prepared by Suzuki cross-couplings on suitable halogenated derivatives of DHA. The synthesis presents an expansion of our......, incorporating a p-MeSC6H4 anchoring group in one end, has been placed in a silver nanogap. Conductance measurements justify that transport through both DHA (high resistivity) and VHF (low resistivity) forms goes by sequential tunneling. The switching is fairly reversible and reenterable; after more than 20 ON...

  12. Dihydroazulene Photochromism:Synthesis, Molecular Electronics and Hammett Correlations

    DEFF Research Database (Denmark)

    Broman, Søren Lindbæk

    This thesis describes the development of a versatile synthetic protocol for preparation of a large selection of dihydroazulenes (DHAs) with both electron withdrawing and donating groups. By UV-Vis and NMR spectroscopies and even in a single-molecule junction, their ability to undergo a light...... will be discussed in detail. The second chapter describes the design and synthesis of DHA/VHFs intended for use in molecular electronics and their solution and single-molecule junction switching properties. By the expansion of the recently reported procedure for functionalization of this system by Suzuki cross...

  13. Development of 1-aryl-3-furanyl/thienyl-imidazopyridine templates for inhibitors against hypoxia inducible factor (HIF)-1 transcriptional activity.

    Science.gov (United States)

    Fuse, Shinichiro; Ohuchi, Toshiaki; Asawa, Yasunobu; Sato, Shinichi; Nakamura, Hiroyuki

    2016-12-15

    1,3-Disubstituted-imidazopyridines were designed for developing inhibitors against HIF-1 transcriptional activity. Designed compounds were rapidly synthesized from a key aromatic scaffold via microwave-assisted Suzuki-Miyaura coupling/CH direct arylation sequence. Evaluation of ability to inhibit the hypoxia induced transcriptional activity of HIF-1 revealed that the compound 2i and 3a retained the same level of the inhibitory activity comparing with that of known inhibitor, YC-1 (1). Identified, readily accessible 1-aryl-3-furanyl/thienyl-imidazopyridine templates should be useful for future drug development. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. 1,4-Dihexyloxy-2,5-bis(2-nitrophenylbenzene

    Directory of Open Access Journals (Sweden)

    Norma Wrobel

    2012-04-01

    Full Text Available The title compound, C30H36N2O6, was prepared via twofold Suzuki coupling of a diboronic acid with bromonitrobenzene. The molecule is located on a crystallographic inversion centre. The lateral benzene ring and the central ring make a dihedral angle of 48.75 (14° and the nitro group is twisted by 41.47 (13° out of the plane of the benzene ring. The nitro and hexyloxy groups are in close proximity and the hexyloxy chain adopts an all-anti conformation.

  15. Dynamics of dissolved organic carbon in the northwestern Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    DileepKumar, M.; Rajendran, A.; Somasundar, K.; Haake, B.; Jenisch, A.; Shuo, Z.; Ittekkot, V.; Desai, B.N.

    scatter of DOC and AOU data points. This scatter could have been also the result of POC oxida- tion to CO2. Sugimura and Suzuki (1988) have observed an inverse correlation be- tween AOU and DOC in the waters of the northwestern Pacific and claimed....e. positive AN) predominantly in the northern Arabian Sea. The slope of the regression line for all the points (-0.035) shows lower DOC values when AN is positive, indicating oxidation by NOj-. The most interest- ing part of the inverse trend in toto is...

  16. Disease: H00146 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00146 Alpha-N-acetylgalactosaminidase deficiency, including: Schindler disease; K...ided into three types. Type 1 is Schindler disease, characterized by mental retardation, spasticity ,and myo...n alpha-N-acetylgalactosaminidase deficiency (Schindler/Kanzaki disease). ... JOURNAL ... J Hum Genet 49:1-8 (20... ... TITLE ... The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler a...eland AM, de Jong JG, Wevers RA, Renier WO, Schindler D, Coll MJ, Chabas A, Sakuraba H, Suzuki Y, van Diggel

  17. Korean Affairs Report

    Science.gov (United States)

    1986-09-09

    U.S. Volvo 13. Other 14. Subtotal 15. Toyota 16. Nissan 17. Honda 18. Mazda 19. Mitsubishi 20. Fujitsu 21. Isuzu 22. Suzuki 23. Japanese...cars & Percent Unit=1,000 3. Company 4. U.S.-Made Cars 5. Imported Cars 6. GM 7. Ford 8. Chrysler 9. AMC 10. U.S. Nissan 11. U.S. Honda 12...24 percent. This is a surprisingly large increase compared with the current 1.7 percent. Until 1983, the prospect of Korean automobile exports was

  18. Enabling high-mobility, ambipolar charge-transport in a DPP-benzotriazole copolymer by side-chain engineering

    DEFF Research Database (Denmark)

    Gruber, Mathias; Jung, Seok-Heon; Schott, Sam

    2015-01-01

    In this article we discuss the synthesis of four new low band-gap co-polymers based on the diketopyrrolopyrrole (DPP) and benzotriazole (BTZ) monomer unit. We demonstrate that the BTZ unit allows for additional solubilizing side-chains on the co-monomer and show that the introduction of a linear...... side-chain on the DPP-unit leads to an increase in thin-film order and charge-carrier mobility if a sufficiently solubilizing, branched, side chain is attached to the BTZ. We compare two different synthetic routes, direct arylation and Suzuki-polycondensation, by a direct comparison of polymers...

  19. Taxonomic study on the subgenus Uresipedilum (Diptera: Chironomidae: Polypedilum, with description of a new species from the Yaewyama Islands, Okinawa, Japan

    Directory of Open Access Journals (Sweden)

    Nao Yamamoto

    2015-07-01

    Full Text Available As a result of a multi-year survey, we recognized four species including a new species of the subgenus Uresipedilum from the Yaeyama Islands, the Ryukyus, Japan. Polypedilum (Uresipedilum paraconvictum sp. nov. is described. P. (U. classiglobum Zhang et Wang (2004 P. (U. bingoparadoxum Kawai et al. (1998 and P. (U. iriofegeum Sasa et Suzuki (2000 are re-described. The first species is newly recorded from Japan, and the second species is new to the Ryukyus. The diagnostic characters of the subgenus are discussed.

  20. Double N-arylation reaction of polyhalogenated 4,4’-bipyridines. Expedious synthesis of functionalized 2,7-diazacarbazoles

    Directory of Open Access Journals (Sweden)

    Mohamed Abboud

    2012-02-01

    Full Text Available Unusual 2,7-diazacarbazoles were prepared in one step from readily available tetra-halogenated 4,4’-bipyridines by using a double N-arylation reaction in the presence of the Pd–XPhos catalyst system. Moderate to good yields were obtained in this site-selective Buchwald–Hartwig double amination. The functionalization of these tricyclic derivatives was performed by using Pd-catalyzed cross-coupling reactions such as the Stille and Suzuki couplings. Two compounds were analyzed by X-ray diffraction and show π–π stacking involving the diazacarbazole moieties and the phenyl rings of functionalized groups.

  1. Kiri Pariisist / Aire Allikmets

    Index Scriptorium Estoniae

    Allikmets, Aire

    1998-01-01

    1997-1999 toimuvast Jaapani aastast Prantsusmaal ja Prantsuse aastast Jaapanis. Prantsuse Rahvuslikus Keraamikamuuseumis keraamikanäitus "Cordes de feu", tuhat aastat jaapani keraamikat Bisenis, Nabeshima ülikute portselan. Keraamik Suzuki Osamu isikunäitus ja 170 jaapani kalligraafi tööd "Les Ma̋tres de l'encre" Espace des Arts Mitsukoshi-Etoile'is. Prantsuse aasta avaakord - Statue de la Liberté eksponeerimine Tokios. Tokio rahvusmuuseumis Delacroix' maal "Vabadus juhib rahvast barrikaadidele". Kavasolevaid prantsuse kunsti näitusi.

  2. Ruthenium Hydride/Brønsted Acid-Catalyzed Tandem Isomerization/N-Acyliminium Cyclization Sequence for the Synthesis of Tetrahydro-β-carbolines

    DEFF Research Database (Denmark)

    Hansen, Casper Lykke; Clausen, Janie Regitse Waël; Ohm, Ragnhild Gaard

    2013-01-01

    This paper describes an efficient tandem sequence for the synthesis of 1,2,3,4-tetrahydro-β-carbolines (THBCs) relying on a ruthenium hydride/Brønsted acid- catalyzed isomerization of allylic amides to N-acyliminium ion intermediates which are trapped by a tethered indolenucleophile. The methodol...... the Suzuki cross-coupling reaction to the isomerization/N-acyliminium cyclization sequence. Finally, diastereo- and enantioselective versions of the title reaction have been examined using substrate control (with dr >15: 1) and asymmetric catalysis (ee up to 57%), respectively...

  3. Potassium 3-formyl-[1,1′-biphenyl]-4-olate monohydrate

    Directory of Open Access Journals (Sweden)

    Ryoji Moriwaki

    2017-09-01

    Full Text Available The title salt, K+·C13H9O2−·H2O, was synthesized from 5-bromosalicylaldehyde and a phenylboronic acid derivative using the Suzuki–Miyaura cross-coupling reaction (Miyaura & Suzuki, 1979. In addition to the intermolecular interactions between the charged species, two O—H...O hydrogen bonds involving the isolated water molecules further stabilize the crystal packing of the title salt leading to the formation of a three-dimensional framework structure.

  4. Advanced materials for clean energy

    CERN Document Server

    Xu (Kyo Jo), Qiang

    2015-01-01

    Arylamine-Based Photosensitizing Metal Complexes for Dye-Sensitized Solar CellsCheuk-Lam Ho and Wai-Yeung Wongp-Type Small Electron-Donating Molecules for Organic Heterojunction Solar CellsZhijun Ning and He TianInorganic Materials for Solar Cell ApplicationsYasutake ToyoshimaDevelopment of Thermoelectric Technology from Materials to GeneratorsRyoji Funahashi, Chunlei Wan, Feng Dang, Hiroaki Anno, Ryosuke O. Suzuki, Takeyuki Fujisaka, and Kunihito KoumotoPiezoelectric Materials for Energy HarvestingDeepam Maurya, Yongke Yan, and Shashank PriyaAdvanced Electrode Materials for Electrochemical Ca

  5. An Alternating 5,5-Dimethylcyclopentadiene-based Copolymer prepared at Room Temperature for High Performance Organic Thin Film Transistors

    KAUST Repository

    Fei, Zhuping; Chen, Lei; Han, Yang; Gann, Eliot; Chesman, Anthony; McNeill, Christopher R.; Anthopoulos, Thomas D.; Heeney, Martin; Pietrangelo, Agostino

    2017-01-01

    We report that the inclusion of non-aromatic 5,5-dimethylcyclopentadiene monomer into a conjugated backbone is an attractive strategy to high performance semiconducting polymers. The use of this monomer enables a room temperature Suzuki copolymerization with a diketopyrrolopyrrole comono-mer to afford a highly soluble, high molecular weight material. The resulting low band gap polymer exhibits excellent photo and thermal stability, and despite a large π-π stacking distance of 4.26 Å, it demonstrates excellent performance in thin-film transistor devices.

  6. Riemann-Roch Spaces and Linear Network Codes

    DEFF Research Database (Denmark)

    Hansen, Johan P.

    We construct linear network codes utilizing algebraic curves over finite fields and certain associated Riemann-Roch spaces and present methods to obtain their parameters. In particular we treat the Hermitian curve and the curves associated with the Suzuki and Ree groups all having the maximal...... number of points for curves of their respective genera. Linear network coding transmits information in terms of a basis of a vector space and the information is received as a basis of a possibly altered vector space. Ralf Koetter and Frank R. Kschischang %\\cite{DBLP:journals/tit/KoetterK08} introduced...... in the above metric making them suitable for linear network coding....

  7. Crystal structure of 1,3-bis(2,3-dimethylquinoxalin-6-ylbenzene

    Directory of Open Access Journals (Sweden)

    Charles E. Diesendruck

    2015-12-01

    Full Text Available The title compound, C26H22N4 (I, was synthesized by C—H iridium-catalyzed borylation followed by Suzuki coupling. The molecular structure of (I consists of a central benzene ring with 3-dimethylquinoxalin-6-yl groups at the 1 and 3 positions. These 2,3-dimethylquinoxalin-6-yl groups twist significantly out of the plane of the benzene ring. There are intermolecular π–π interactions which result in a two-dimensional extended structure. The layers extend parallel to the ab plane and stack along the c axis.

  8. Quantum phase transition and critical phenomena

    International Nuclear Information System (INIS)

    Dutta, A.; Chakrabarti, B.K.

    1998-01-01

    We intend to describe briefly the generic features associated with the zero temperature transition in quantum mechanical systems. We elucidate the discussion of the introductory section using the very common example of Ising model in a transverse field. We discuss the method of fermionisation for one dimensional systems. The quantum-classical correspondence is discussed using Suzuki-Trotter method. We then introduce the quantum rotor model and discuss its spherical limit. We finally discuss novel features arising due to the presence of quenched randomness in the quantum Ising and rotor systems. (author)

  9. Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.

    Directory of Open Access Journals (Sweden)

    CHRISTOPHE eLEN

    2015-02-01

    Full Text Available Nucleoside analogues have attracted much attention due to their potential biological activities. Amongst all synthetic nucleosides, C5-modified pyrimidines and C7- or C8-modified purines have mostly been prepared using palladium cross-coupling reactions and then studied as antitumoral and antiviral agents. Our objective is to focus this review on the Suzuki-Miyaura and on the Heck cross-couplings of nucleosides using microwave irradiations which are an alternative technology compatible with green chemistry and sustainable development.

  10. Watermelon rind-mediated green synthesis of noble palladium nanoparticles: catalytic application

    Science.gov (United States)

    Lakshmipathy, R.; Palakshi Reddy, B.; Sarada, N. C.; Chidambaram, K.; Khadeer Pasha, Sk.

    2015-02-01

    The present study reports the feasibility of synthesis of palladium nanoparticles (Pd NPs) by watermelon rind. The aqueous extract prepared from watermelon rind, an agro waste, was evaluated as capping and reducing agent for biosynthesis of palladium nanoparticles. The formation of Pd NPs was visually monitored with change in color from pale yellow to dark brown and later monitored with UV-Vis spectroscopy. The synthesized Pd NPs were further characterized by XRD, FTIR, DLS, AFM and TEM techniques. The synthesized Pd NPs were employed in Suzuki coupling reaction as catalyst. The results reveal that watermelon rind, an agro waste, is capable of synthesizing spherical-shaped Pd NPs with catalytic activity.

  11. An Alternating 5,5-Dimethylcyclopentadiene-based Copolymer prepared at Room Temperature for High Performance Organic Thin Film Transistors

    KAUST Repository

    Fei, Zhuping

    2017-06-05

    We report that the inclusion of non-aromatic 5,5-dimethylcyclopentadiene monomer into a conjugated backbone is an attractive strategy to high performance semiconducting polymers. The use of this monomer enables a room temperature Suzuki copolymerization with a diketopyrrolopyrrole comono-mer to afford a highly soluble, high molecular weight material. The resulting low band gap polymer exhibits excellent photo and thermal stability, and despite a large π-π stacking distance of 4.26 Å, it demonstrates excellent performance in thin-film transistor devices.

  12. Observation on optimal transition from conventional energy with resource constraints to advanced energy with virtually unlimited resource, (2)

    International Nuclear Information System (INIS)

    Ohkubo, Hiroo; Suzuki, Atsuyuki; Kiyose, Ryohei

    1983-01-01

    This is an extension of the Suzuki model (base model) on optimal transition from resource-limited energy (oil) to advanced energy with virtually unlimited resource. The finite length of plant life, fuel cost, technological progress factor of advanced energy and the upper limit upon annual consumption rate of oil are taken into account for such an extension. The difference in optimal solutions obtained from extended and base models is shown by an application of the maximum principle. The implication of advanced energy R and D andenergy conservation effort is also discussed. (author)

  13. Comments on derivation of an index for evaluating economics of cogeneration systems and its applications

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, R [Indian Inst. of Tech., Bombay (India). Dept. of Mechanical Engineering

    1990-04-01

    Industrial cogeneration systems usually must satisfy a power load and heat loads at different temperatures. The limitations of the economic index proposed by Pak and Suzuki for such cogeneration systems is discussed in this paper. The importance of a rational exergetic basis for evaluation of different grades of energy is emphasised. Thermodynamic criteria, e.g. the exergetic efficiency, relative fuel savings and fuel chargeable to power, are shown to provide useful information regarding cogeneration options. Any assessment scheme for cogeneration schemes must incorporate thermodynamic criteria in addition to economic criteria. (author).

  14. N-Methylamino Pyrimidyl Amides (MAPA): Highly Reactive, Electronically-Activated Amides in Catalytic N-C(O) Cleavage.

    Science.gov (United States)

    Meng, Guangrong; Lalancette, Roger; Szostak, Roman; Szostak, Michal

    2017-09-01

    Despite recent progress in catalytic cross-coupling technologies, the direct activation of N-alkyl-N-aryl amides has been a challenging transformation. Here, we report the first Suzuki cross-coupling of N-methylamino pyrimidyl amides (MAPA) enabled by the controlled n N → π Ar conjugation and the resulting remodeling of the partial double bond character of the amide bond. The new mode of amide activation is suitable for generating acyl-metal intermediates from unactivated primary and secondary amides.

  15. Solid-phase synthesis of isoxazoles using vinyl ethers as chameleon catches.

    Science.gov (United States)

    Barrett, A G; Procopiou, P A; Voigtmann, U

    2001-10-04

    [reaction: see text] Regioselective 1,3-dipolar cycloadditions of supported vinyl ethers R(1)C(=CH(2))O-CH(2)-polymer, prepared by the Tebbe olefination of R(1)CO(2)-CH(2)-polymer, with ethyl cyanoformate N-oxide gave supported isoxazoline derivatives. Release from the support under mild acidic conditions gave the isoxazoles ethyl 5-R(1)-isoxazole-3-carboxylates. Alternatively, further on-resin functionalization of the R(1) substituent using Suzuki coupling reactions and release from the support under acidic conditions gave more structurally diverse isoxazoles.

  16. JPRS Report Science & Technology Japan Future Prospects of FA-From FA to IMS

    Science.gov (United States)

    1989-12-04

    of FA Investment (Large Companies) a) m d) m 5000fI~ljl|S 1 m± ¥-1$ 500~1000t| 300~500(f 1000~3000ft i) £ÜÜ 0i!§£3^ SWOT # H^fc3S j) k) 1...is a method conceived by Toyota Motors, now widely understood throughout the world. Such information as the production volume, time, method and...T. Suzuki Toyota Motor Corp. Y. Tatsue AIST, Mechanical Engineering Laboratory K. Togino Komatsu Ltd. H. Torii Nihon Keizai Shimbun Editorial

  17. Phase transitions in the random field Ising model in the presence of a transverse field

    Energy Technology Data Exchange (ETDEWEB)

    Dutta, A.; Chakrabarti, B.K. [Saha Institute of Nuclear Physics, Bidhannagar, Calcutta (India); Stinchcombe, R.B. [Saha Institute of Nuclear Physics, Bidhannagar, Calcutta (India); Department of Physics, Oxford (United Kingdom)

    1996-09-07

    We have studied the phase transition behaviour of the random field Ising model in the presence of a transverse (or tunnelling) field. The mean field phase diagram has been studied in detail, and in particular the nature of the transition induced by the tunnelling (transverse) field at zero temperature. Modified hyper-scaling relation for the zero-temperature transition has been derived using the Suzuki-Trotter formalism and a modified 'Harris criterion'. Mapping of the model to a randomly diluted antiferromagnetic Ising model in uniform longitudinal and transverse field is also given. (author)

  18. Edit distance for marked point processes revisited: An implementation by binary integer programming

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Yoshito; Aihara, Kazuyuki [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505 (Japan)

    2015-12-15

    We implement the edit distance for marked point processes [Suzuki et al., Int. J. Bifurcation Chaos 20, 3699–3708 (2010)] as a binary integer program. Compared with the previous implementation using minimum cost perfect matching, the proposed implementation has two advantages: first, by using the proposed implementation, we can apply a wide variety of software and hardware, even spin glasses and coherent ising machines, to calculate the edit distance for marked point processes; second, the proposed implementation runs faster than the previous implementation when the difference between the numbers of events in two time windows for a marked point process is large.

  19. Taxonomic notes on Chironomidae (Diptera from Okinawa Island, Japan, with the description of three new species

    Directory of Open Access Journals (Sweden)

    Masaru Yamamoto

    2015-07-01

    Full Text Available Three new species: Ionthosmittia cuneipenne sp. nov., Orthocladius (Euorthocladius okinawanus sp. nov. and Parakiefferiella semiovata sp. nov., are described from Okinawa Island, Ryukyus, Japan. In addition to these species, twelve species are newly recorded from this island. Diagnostic characters of Tokyobrillia tamamegaseta (Kobayashi et Sasa are emended. Pentapedilum yakuabeum Sasa et Suzuki syn. nov. and Polypedilum yakucedeum Sasa et Suizuki syn. nov. are junior synonyms of Ainuyusurika tuberculatum (Tokunaga. Einfeldia kanazawai (Yamamoto is transferred to the genus Chironomus Meigen and its systematic position is discussed.

  20. Synthesis of 2,6-Substituted 7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted 5-(Het)aryl-pyrrolo[2,3-d]pyrimidines)

    Czech Academy of Sciences Publication Activity Database

    Sabat, Nazarii; Smolen, Sabina; Nauš, Petr; Perlíková, Pavla; Cebová, M.; Poštová Slavětínská, Lenka; Hocek, Michal

    2017-01-01

    Roč. 49, č. 20 (2017), s. 4623-4650 ISSN 0039-7881 R&D Projects: GA ČR(CZ) GA16-00178S; GA MZd(CZ) NV15-31984A Grant - others:AV ČR(CZ) AP1501 Program:Akademická prémie - Praemium Academiae Institutional support: RVO:61388963 Keywords : deazapurines * pyrrolo[2,3-d]pyrimidines * nucleobases * Suzuki-Miyaura cross-coupling * deprotection * demethylation Subject RIV: CC - Organic Chemistry OBOR OECD: Organic chemistry Impact factor: 2.650, year: 2016