WorldWideScience

Sample records for tokyo filmifestival nitas

  1. Tokyo filmifestival näitas Aasia tippe / Pille-Riin Pregel

    Index Scriptorium Estoniae

    Pregel, Pille-Riin

    2001-01-01

    Tokyo filmifestivalist. Lähemalt Tai mängufilmist "Ohtlik Bangkok" ("Bangkok Dangerous") : režissöörid vennad Oxide ja Danny Pang ning Iraani "Kuupaiste all" ("Under the Moonlight" : režissöör Reza Mir-Karimi. Peaauhinna sai Albaania mängufilm "Loosungid2 ("Slogans"), mille režissöör Gjergj Xhuavani sai ka parima režissööri auhinna. Lisatud võitjate nimekiri

  2. Pärnu filmifestival taas ETVs

    Index Scriptorium Estoniae

    2007-01-01

    XXI Rahvusvaheline Pärnu filmifestival : Eesti Televisioon näitab 8.-14.07. eriprogrammi, kuhu on valitud filmid "Minu surm, mitte sinu" (Saksamaa-India 2006), "Valgevene õppetund" (Poola-Valgevene 2006), "Beslan - õigus elada" (Venemaa 2006), "Esimene rahu õppetund" (Iisrael 2006), "Õnne vaenlased" (Taani-Afganistan 2006), "Mu tütar on terrorist" (Norra 2006) ja "Lugu kehast" (Iisrael 2006)

  3. Bhandari, Dr Nita

    Indian Academy of Sciences (India)

    Elected: 2015 Section: Medicine. Bhandari, Dr Nita Ph.D. (JNU), FAMS. Date of birth: 9 November 1955. Specialization: Nutrition-Infection Interaction, Child Health, Nutritional Interventions, Clinical Evaluation of Vaccine Address: President & Director, Centre for Health R&D Society for Applied Studies, 45, Kalu Sarai, New ...

  4. Kuuekümnes Cannes'i filmifestival alustas rullumist / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2007-01-01

    Algas 60. Cannes'i filmifestival. Pikemalt avafilmist - Wong Kar-Wai "My Blueberry Nights", festivali ajaloost ja korraldusest, eestlaste osalemisest (K. Kõusaar filmiga "Magnus", filmiturul "Klass" ja "Sügisball")

  5. Järgmisel nädalal algab Veneetsia filmifestival / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    Tänavune Veneetsia filmifestival toimub 30. augustist 9. septembrini. Kuldlõvile kandideerib 20 filmi, žüriid juhib Catherine Deneuve, elutööpreemia saab David Lynch. Festival algab Brian de Palma filmiga "Must daalia"

  6. Tokyo Jane

    DEFF Research Database (Denmark)

    Austin, Robert D.; Minbaeva, Dana; Schafer, Simon

    2014-01-01

    Tokyo Jane is an accessible fashion jewelry company that makes and markets its products as “luxury for less” by designing, importing and selling fashion jewelry pieces that look luxurious but cost only a fraction of the high-priced items that inspired them. Finished products are air-shipped to co......Tokyo Jane is an accessible fashion jewelry company that makes and markets its products as “luxury for less” by designing, importing and selling fashion jewelry pieces that look luxurious but cost only a fraction of the high-priced items that inspired them. Finished products are air......-shipped to company headquarters in Copenhagen, Denmark from factories in China, stocked in the head office and delivered to 400 retail partners —small fashion boutiques, big department stores and online shops — who then sell to consumers in Europe, Scandinavia, the United Kingdom and Canada. The two partners who...... founded the firm in 2005 are facing several problems: the brand definition is not well enough developed to support the next stage in the firm’s growth, certain challenges have outstripped available human resources — they have only three permanent employees and a revolving number of interns...

  7. Tokyo Jane

    DEFF Research Database (Denmark)

    Austin, Robert D.; Minbaeva, Dana; Schafer, Simon

    2014-01-01

    Tokyo Jane is an accessible fashion jewelry company that makes and markets its products as “luxury for less” by designing, importing and selling fashion jewelry pieces that look luxurious but cost only a fraction of the high-priced items that inspired them. Finished products are air......-shipped to company headquarters in Copenhagen, Denmark from factories in China, stocked in the head office and delivered to 400 retail partners —small fashion boutiques, big department stores and online shops — who then sell to consumers in Europe, Scandinavia, the United Kingdom and Canada. The two partners who...... — and distribution operations and management need to be rethought as the firm rapidly increases the scale of its operations. Things come to a head in April 2013, when they are confronted by an important customer about quality issues with their products. How can they not only save their company but continue to grow?...

  8. Tokyo / Karin Thea

    Index Scriptorium Estoniae

    Karin, Thea

    2013-01-01

    Tokyo vaatamisväärtused: Sky Tree teletorn, Takeshita Dori jalakäijate tänav, Asakusa linnaosa, The Gate Hotel, Tokyo metroo, Ryogoku Kokugikan, Nippon Kasgaku Miraikan ning Jaapani suurim kalaturg Tsukiji

  9. Learning from Tokyo urbanism

    DEFF Research Database (Denmark)

    Greve, Anni

    2013-01-01

    This article takes up the challenge of demonstrating that ‘we’ can learn from Tokyo about the intrinsic importance of in-between realms to a cosmopolitan culture: the urban sanctuaries. It has four sections. The first section encircles a location from where to learn from Tokyo as well as an angle...

  10. Leucemia congénita aguda

    Directory of Open Access Journals (Sweden)

    Nilvia Esther González García

    2011-06-01

    Full Text Available La leucemia aguda durante el período neonatal es poco frecuente de evolución rápida y pronóstico sombrío. Sus características clínicas y biológicas difieren de las encontradas en niños de mayor edad, y su inicio se caracteriza por afectación cutánea, hepatoesplenomegalia, hiperleucocitosis e infiltración del sistema nervioso central. Se han observado pacientes con formas tanto mieloides como linfoides, pero la leucemia mieloide aguda parece predominar en esta etapa de la vida. Se presenta el caso de un paciente con leucemia congénita clasificada morfológicamente, con aparición de manifestaciones clínicas de enfermedad hematológica desde el nacimiento y diagnóstico de leucemia linfoblástica aguda congénita.

  11. The metropolis of Tokyo.

    Science.gov (United States)

    Russoff, D

    1986-04-01

    The Tokyo metropolis houses 11,892,016 people, 1/10 of the Japanese population. In recent years, Tokyo's population growth has slowed as the birthrate has fallen from a 1947 postwar high of 31.5/1000 to 11.4/1000 in 1983. 5.9 million males and 5.8 million females, composing 4 1/2 million households, live in Tokyo's 2160 square kilometers. Within the metropolis' 23 wards, density per square kilometer was 14,023 persons in 1983, with Toshima ward containing 21,844 people per square kilometer. Wards around the city's center held 71% of the population in 1983, but had only 27% of its land mass; outlying cities, towns, and villages held 28% of the population on 54% of the land. 50% of Tokyo's population is aged 25-59; those 65 or over will rise from 1980's 9% to 15.6% of the population in 2000. In 40 years, Japan will have more elderly people than any other advanced country. In 1983, Tokyo had over 150,000 housing starts, high by Japanese and international standards. Nearly 1/4 of Tokyo households each contain a married couple with 2 children, but single person households predominate, reflecting Tokyo's student, working bachelor, and elderly populations. Young, single Japanese workers spend 1/3 of their income on leisure, entertainment, cultural activities and education; couples marry late and, with 2 incomes, can purchase many nonessentials. Nearly 3.25 million students attend Tokyo's fiercely competitive schools and colleges; Japan is almost 100% literate. Of the 6 million people working in Tokyo, half work in the service and retail sector, 25% in manufacturing, 12% in transportation and communication, 9% in finance and insurance, and 8% work in construction. Tokyo workers earn nearly 20% more than the average Japanese worker. Japan now faces job shortages and will see many unemployment problems by 1990. To help absorb new workers, government planners recommend increasing vacation time, training workers as specialists rather than generalists, and encouraging job

  12. The Tokyo axion helioscope

    International Nuclear Information System (INIS)

    Ohta, R.; Akimoto, Y.; Inoue, Y.; Minowa, M.; Mizumoto, T.; Moriyama, S.; Namba, T.; Takasu, Y.; Yamamoto, A.

    2012-01-01

    The Tokyo Axion Helioscope experiment aims to detect axions which are produced in the solar core. The helioscope uses a strong magnetic field in order to convert axions into X-ray photons and has a mounting to follow the sun very accurately. The photons are detected by an X-ray detector which is made of 16 PIN-photodiodes. In addition, a gas container and a gas regulation system are adopted for recovering the coherence between axions and photons in the conversion region giving sensitivity to axions with masses up to 2 eV. In this paper, we report on the technical detail of the Tokyo Axion Helioscope.

  13. Malformaciones Congénitas Músculo Esqueléticas

    OpenAIRE

    Ugarte Velarde, Pablo

    2010-01-01

    La mayoría de las malformaciones congénitas, son de causa desconocida, y muchas veces se asocian a otras malformaciones orgánicas como malformaciones cardiacas, de vías urinarias o sistema digestivo. Por eso es de suma importancia valorar al paciente en forma integral. Las malformaciones congénitas se presentan en 6 % de los nacidos vivos, y de ellas 1% son múltiples.Las anomalías congénitas se pueden clasificar como; malformativas que es la formación anómala del tejido fetal Deformación que ...

  14. The Tokyo Declaration 1997

    International Nuclear Information System (INIS)

    1998-01-01

    In this chapter the text of the Tokyo declaration is included. The specific recommendations and propositions for action (A) The finance questions; (B) The transfer of the technologies; (C) The reform of samples of production and consumption; (D) The science/technology and information/communication are reviewed

  15. La tibia y sus deformidades congénitas

    Directory of Open Access Journals (Sweden)

    Valentín Malagón Castro

    1955-06-01

    Full Text Available El presente estudio sobre la Tibia y sus anomalías congénitas lo hemos dividido en 2 grandes capítulos. En el primero bosquejamos sintéticamente los caracteres anatómicos y radiológicos del hueso tibial sano. En el segundo, pasamos revista a las deformidades congénitas de la Tibia: Ausencia, Amputaciones, Incurvaciones, Pseudoartrosis, etc.

  16. Getting Lost in Tokyo

    Directory of Open Access Journals (Sweden)

    Raymond Lucas

    2014-07-01

    Full Text Available This paper explores the potential for using alternative forms of inscriptive practice to describe the urban space of the Tokyo Subway. I begin with an account of the process of getting lost in Shinjuku Subway Station in the heart of Tokyo. This station represents a limit condition of place, being dense and complex beyond the powers of traditional architectural representation. The station is explored through serial translations, beginning with narrative, moving to a flowchart diagram, Laban dance notation, recurring motifs and archetypes, architectural drawing, photography, and cartography. As Claudia Brodsky Lacour and Tim Ingold describe, the form our inscriptive practices take are crucial to the ways in which we conceptualise those places. How much of the experience of a place is lost in the traditional inscriptive practices of the architect? This description of the urban space of the Tokyo subway forms the basis for an extended study exploring the description of this experience of place, and the power of such description to theorise space. The ultimate aim of this is to shift the focus of urban design away from geometric principles and towards the experiences that might be enjoyed in such places.

  17. "Ruudi" võitis Tokyos

    Index Scriptorium Estoniae

    2006-01-01

    Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

  18. Tumores neonatales y malformaciones congénitas

    Science.gov (United States)

    Tornero, O. Berbel; García, J.A. Ortega; Tortajada, J. Ferrís i; Castell, J. García; Colomer, J. Donat i; Soldin, O.P.; Soler, J.L. Fuster

    2013-01-01

    Introducción La asociación entre tumores y malformaciones congénitas está bien establecida, pero no existen datos exclusivos en el período neonatal y se desconocen los mecanismos subyacentes que generan dicha relación. Objetivos Este trabajo tiene dos objetivos: primero, analizar la frecuencia de los tumores neonatales asociados a malformaciones congénitas, y segundo, comentar las posibles hipótesis etiopatogénicas de la relación entre ambas entidades. Materiales y método Estudio retrospectivo de las historias clínicas de los tumores neonatales, en el Hospital Universitario Materno- Infantil La Fe de Valencia, desde enero de 1990 hasta diciembre de 1999. Selección y descripción de las variedades histológicas asociadas a malformaciones congénitas. Éstas se han agrupado siguiendo los criterios de la Clasificación Internacional de Enfermedades CIE-9, códigos 740.0–759.9. Revisión sistemática bibliográfica de los últimos 25 años, obtenida del Medline, Cancerlit, Index Citation Science y Embase. El perfil de búsqueda utilizado fue la combinación de “neonatal/congenital-tumors/cancer/neoplasms” y “congenital malformations/birth defects”. Resultados Se identificaron 72 tumores neonatales (2,8 % del total de tumores pediátricos diagnosticados en dichos años) y 15 de ellos (20,8 %) asociados a malformaciones congénitas, enfermedades o síndromes congénitos. Las asociaciones entre tumores neonatales y malformaciones congénitas fueron las siguientes: a) angioma en 3 pacientes: con dos cardiopatías congénitas y una atresia de coanas-laringomalacia; b) neuroblastoma en 2 pacientes: uno con riñón en herradura y anomalías vertebrales, y otro con cardiopatía congénita; c) teratoma en 2 pacientes: uno con fisura palatina y anomalías vertebrales, y otro con metatarso varo; d) tumor del sistema nervioso central en un paciente con hernia de Bochdaleck; e) tumor cardíaco en 4 pacientes con esclerosis tuberosa; f) leucemia aguda en un

  19. Hernia diafragmática congénita atascada

    Directory of Open Access Journals (Sweden)

    Miurkis Endis Miranda

    Full Text Available La hernia diafragmática congénita constituye uno de los retos pendientes dentro de las enfermedades quirúrgicas del recién nacido. Se presenta un caso muy inusual, en el cual se diagnosticó una hernia diafragmática derecha atascada, con compromiso de gran parte del intestino. Se describen los medios diagnósticos utilizados, el procedimiento quirúrgico realizado y las complicaciones presentadas. La hernia diafragmática congénita atascada es una complicación potencialmente letal, por el amplio compromiso vascular que produce en los órganos abdominales y que conlleva a la necrosis de estos si no se diagnostica precozmente. Por ello, debe ser considerada en el diagnóstico diferencial de la insuficiencia respiratoria en los recién nacidos y lactantes pequeños.

  20. Lithuanian trade mission visits Tokyo

    Index Scriptorium Estoniae

    2010-01-01

    Leedu välisministri Andronius Azubalise ja Jaapani välisministri Seiji Maehara kohtumisel räägiti riikidevahelisest koostööst. Tokyo visiidi ajal kohtus välisminister ka alamkoja väliskomitee esimehe Tadamasa Kodaira ja majandus- ja tööstusministri asetäitja Motohisa Ikedaga

  1. Tokyo Motor Show 2003; Tokyo Motor Show 2003

    Energy Technology Data Exchange (ETDEWEB)

    Joly, E.

    2004-01-01

    The text which follows present the different techniques exposed during the 37. Tokyo Motor Show. The report points out the great tendencies of developments of the Japanese automobile industry. The hybrid electric-powered vehicles or those equipped with fuel cells have been highlighted by the Japanese manufacturers which allow considerable budgets in the research of less polluting vehicles. The exposed models, although being all different according to the manufacturer, use always a hybrid system: fuel cell/battery. The manufacturers have stressed too on the intelligent systems for navigation and safety as well as on the design and comfort. (O.M.)

  2. Tokyo Tower and Tokyo Skytree: History and Symbolism in Contemporary Japan

    OpenAIRE

    Yunuen Ysela Mandujano-Salazar

    2016-01-01

    The Tokyo Tower and the Tokyo Skytree are the two most recognizable landmarks on the skyline of Japan’s capital. By means of a documental revision, a textual interpretative analysis of media contents, participant observation and unstructured interviews, the objective of this article is to identify the development of these towers as symbols of Tokyo and Japan. It is found that, with more than half a century of existence, the Tokyo Tower represents the successful post-war Japanese society, whil...

  3. Leucemia congénita aguda Acute congenital leukemia

    Directory of Open Access Journals (Sweden)

    Nilvia Esther González García

    2011-06-01

    Full Text Available La leucemia aguda durante el período neonatal es poco frecuente de evolución rápida y pronóstico sombrío. Sus características clínicas y biológicas difieren de las encontradas en niños de mayor edad, y su inicio se caracteriza por afectación cutánea, hepatoesplenomegalia, hiperleucocitosis e infiltración del sistema nervioso central. Se han observado pacientes con formas tanto mieloides como linfoides, pero la leucemia mieloide aguda parece predominar en esta etapa de la vida. Se presenta el caso de un paciente con leucemia congénita clasificada morfológicamente, con aparición de manifestaciones clínicas de enfermedad hematológica desde el nacimiento y diagnóstico de leucemia linfoblástica aguda congénita.Acute leukemia during neonatal period is not frequent, of a fast course and gloomy prognosis. Its clinical and biological features differ of that present in older children and it onset is characterized by cutaneous affection, hepatosplenomegaly, hyperleukocytosis and infiltration of central nervous system (CNS. There are patients presenting with myeloid and lymphoid types, but the acute leukemia seems to predominate in this stage of life. This is the case of a patient with acute leukemia morphologically classified, with appearance of clinical manifestations of hematologic disease from birth and a diagnosis of congenital acute lymphoblastic leukemia.

  4. Rubéola congénita em Portugal entre 2009 e 2015

    OpenAIRE

    Palminha, Paula; Vinagre, Elsa; Ribeiro, Carlos; Lourenço, Teresa; Roque, Carla

    2015-01-01

    Objetivo: Analisar os resultados do diagnóstico laboratorial de casos suspeitos de rubéola congénita recebidos no Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA) entre 2009 e 2015, ao abrigo do Programa de Eliminação do Sarampo, da Rubéola e da Rubéola Congénita na Região Europeia da Organização Mundial da Saúde (OMS).

  5. New tandem accelerator facility of Tokyo University

    International Nuclear Information System (INIS)

    Kobayashi, Koichi; Hatori, Satoshi; Nakano, Chuichiro

    1993-01-01

    An old tandem accelerator is being replaced by a new one at the University of Tokyo. The new facility consists of a vertical 5 MV Pelletron with two ion sources and dedicated beam lines for fine analytical studies. (orig.)

  6. Sadik brings message to Tokyo.

    Science.gov (United States)

    1990-03-01

    UNFPA Executive Director, Dr. Nafis Sadik, visited Tokyo in February to publicize the organization and its activities. UNFPA worked in 1989 with a US $200 million budget on 3266 projects in 147 countries. Dr Sadik is currently UN Under Secretary General and gave a speech at the College Women's Association on the deterioration of the world environment. Environmental problems stem from industrialization and urbanization. World population will rise to 6.2 billion by 2000 (80% of which are in developing countries) and 8.5 billion by 2025. Developing countries are also becoming dumping grounds for developed countries' waste. Dr. Sadik stresses that women need to change their current status from childbearers to productive members of their societies who ca choose when to have a family and how large it will be. The next decade will be crucial for changes of attitude among governments and the role of non-governmental organizations. Dr. Sadik discussed the importance of Population Forum 21 where 24 Japanese policy makers met to discuss global population problems. She urged Japan to invest more finances, advice, and technical help in this major crisis. She also states that there are no boundaries for environmental and population problems, so we must all work on a solution together. Dr. Sadik praised the efforts of NGO's in this struggle.

  7. Transcriptional regulation of the Rhodococcus rhodochrous J1 nitA gene encoding a nitrilase.

    Science.gov (United States)

    Komeda, H; Hori, Y; Kobayashi, M; Shimizu, S

    1996-01-01

    The 1.4-kb downstream region from a nitrilase gene (nitA) of an actinomycete Rhodococcus rhodochrous J1, which is industrially in use, was found to be required for the isovaleronitrile-dependent induction of nitrilase synthesis in experiments using a Rhodococcus-Escherichia coli shuttle vector pK4 in a Rhodococcus strain. Sequence analysis of the 1.4-kb region revealed the existence of an open reading frame (nitR) of 957 bp, which would encode a protein with a molecular mass of 35,100. Deletion of the central and 3'-terminal portion of nitR resulted in the complete loss of nitrilase activity, demonstrating that nitR codes for a transcriptional positive regulator in nitA expression. The deduced amino acid sequence of nitR showed similarity to a positive regulator family including XylS from Pseudomonas putida and AraC from E. coli. By Northern blot analysis, the 1.4-kb transcripts for nitA were detected in R. rhodochrous J1 cells cultured in the presence of isovaleronitrile, but not those cultured in the absence of isovaleronitrile. The transcriptional start site for nitA was mapped to a C residue located 26 bp upstream of its translational start site. Deletion analysis to define the nitA promoter region suggested the possible participation of an inverted repeat sequence, centered on base pair -52, in induction of nitA transcription. Images Fig. 2 Fig. 5 Fig. 6 PMID:8855219

  8. El tratamiento de la sífilis congénita

    Directory of Open Access Journals (Sweden)

    Facultad de Medicina Revista de la

    1934-01-01

    Full Text Available El American Journal of Diseases de octubre, 1933, publicó un artículo de Atlee y Tyson acerca de la sífilis congénita, en el que prevalece un tono decididamente optimista en comparación con la mayoría de los escritos que han aparecido sobre esta materia. Estos autores declaran que su experiencia les ha demostrado que el tratamiento inmediato de la sífilis congénita, continuado por 14 semanas, da un alto porcentaje de curas.

  9. Nutrición en el lactante con cardiopatías congénitas

    OpenAIRE

    Gutiérrez, María Cielo

    2015-01-01

    Las Cardiopatías Congénitas (CC) son las malformaciones congénitas más frecuentes a nivel mundial con una incidencia de 8 a 10 por cada 1000 recién nacidos. En menores de un año, constituyen una de las principales causas de mortalidad infantil. Los lactantes y niños cardiópatas presentan frecuentemente alteraciones en el crecimiento y desarrollo, siendo mayor el compromiso en aquellos pacientes que presenten insuficiencia cardíaca y cianosis. Objetivos: Identificar las representaciones so...

  10. Aplasia Cutis Congénita: Presentación de un caso

    OpenAIRE

    Rosa María Alonso Uría; Irka Ballesté López

    1998-01-01

    Se reportó el caso de un recién nacido, hijo de madre secundigesta, con una malformación congénita del cuero cabelludo, del tipo aplasia cutis congénita. Se describieron las características clínicas de ésta, su evolución, pronóstico y tratamiento. Se hizo énfasis en el cuidado y la prevención de las complicaciones, fundamentalmente infecciosas, en este tipo de neonatosThe case of a newborn, son of a secundigravida, with a congenital malformation of the scalp denominated aplasia cutis congenit...

  11. Tokyo Tower and Tokyo Skytree: History and Symbolism in Contemporary Japan

    Directory of Open Access Journals (Sweden)

    Yunuen Ysela Mandujano-Salazar

    2016-12-01

    Full Text Available The Tokyo Tower and the Tokyo Skytree are the two most recognizable landmarks on the skyline of Japan’s capital. By means of a documental revision, a textual interpretative analysis of media contents, participant observation and unstructured interviews, the objective of this article is to identify the development of these towers as symbols of Tokyo and Japan. It is found that, with more than half a century of existence, the Tokyo Tower represents the successful post-war Japanese society, while in just five years the Tokyo Skytree has become a symbol of Japanese national spirit and resilience in an era of multiple crises. Both broadcasting towers are regularly portrayed in Japanese media linked to narratives of romance, dreams, family and community. Also, enhanced by their special lightening at night, they stand as attractive backgrounds for locals and visitors in relevant events in their lives.

  12. Sífilis congénita Congenital syphilis

    Directory of Open Access Journals (Sweden)

    Fernando Montoya

    1992-01-01

    Full Text Available

     

    Se discuten diversos aspectos de la sífilis congénita con énfasis en los siguientes: el hecho de que 60% de las madres que engendran niños sifil��ticos no presentan evidencia clínica de la enfermedad; la necesidad de ordenar un mínimo de dos serologías, al comienzo y al final del embarazo, ya que 15% de las embarazadas reactivas lo son sólo al final de la gestación; la disponibilidad de la cordocentesis a partir de la decimaséptima semana del embarazo, con el fin de obtener muestras de sangre para diagnóstico prenatal; la aceptación de 9.600.000 U. de penicilina benzatínica para el tratamiento de la sífilis durante el embarazo; esta dosis evita los casos de niños Infectados que se han observado con el esquema de 7.200.000 U.

     

    Several aspects of congenital syphilis are discussed with emphasis on the fact that 60% of women who give birth to syphilitic children do not have clinical evidence of the disease; the need to order at least two serological tests at the beginning and at the end of pregnancy, because 15% of pregnant women become reactive only at the end of pregnancy; the possibility of obtaining prenatal fetal blood specimens for diagnostic purposes, by cordocenthesis from the seventeenth week of pregnancy on; the acceptance of a dose of 9.600.000 units of benzathine penicillin for the treatment of syphilis during pregnancy to avoid the cases of Infected Infants observed with doses of 7.200.000 units.

  13. Malaria congénita en un hospital de iquitos, Perú

    Directory of Open Access Journals (Sweden)

    Hermann Silva

    Full Text Available Objetivos. Determinar la frecuencia y características clínicas de los recién nacidos con malaria congénita en el Hospital de Apoyo de Iquitos en la Amazonía peruana. Materiales y métodos. Estudio descriptivo, prospectivo y transversal. De enero de 2011 a diciembre de 2013 se estudiaron 14 017 recién nacidos y a sus madres, de quienes se seleccionaron 52 portadoras de malaria gestacional mientras que a sus recién nacidos se les hospitalizó en el Servicio de Neonatología del hospital, y fueron sometidos a evaluación clínica y estudios de laboratorio. Resultados. La frecuencia de malaria gestacional fue de 0,4% y una proporción de malaria congénita de 9,6%. Plasmodium vivax fue hallado en 80% de casos de malaria gestacional y en 60% de malaria congénita. Se observó un caso de óbito fetal con gota gruesa positiva para Plasmodium falciparum. El cuadro clínico en recién nacidos fue fiebre, hipoactividad, irritabilidad y pobre succión. Conclusiones. Se documenta la presencia de malaria congénita en recién nacidos de madres con malaria gestacional. El cuadro clínico se asemeja a una sepsis neonatal. El diagnóstico precoz de malaria congénita y el tratamiento oportuno cursan con buena evolución.

  14. Berlin – Paris – Tokyo. KARTOGRAFI

    DEFF Research Database (Denmark)

    Dinesen, Cort Ross; Larsen, Steen Nepper

    Tokyo. Omkring disse kontekster vil de erfaringer fra Sommerskolens fem år blive videreført som et forskningsfelt, der med udgangspunkt i morfologi indarbejder relationer til topologi, topografi og æstetik, samt omhandler refleksioner omkring en ny urbanitet. Kartografien udgør omdrejningspunktet i...

  15. Apraxia oculomotora congénita Congenital oculomoror apraxia

    Directory of Open Access Journals (Sweden)

    Rosa M Naranjo Fernández

    2010-01-01

    Full Text Available La apraxia oculomotora congénita, también conocida como Síndrome de Cogan, es una enfermedad hereditaria rara que afecta al ojo, caracterizada por la incapacidad para ejecutar movimientos oculares horizontales voluntarios. Descrita por Cogan en 1952, de etiología desconocida, clásicamente se le considera un desorden esporádico, con herencia autosómica dominante en algunos casos y en otros sugieren alteraciones metabólicas parciales o defectos del desarrollo neurológico. Acude al servicio de oftalmología pediátrica un paciente masculino de ocho meses de edad y al examen de motilidad ocular se detecta que cuando el niño intenta mover los ojos hacia el objeto que le llama la atención, realiza movimientos bruscos laterales de la cabeza. Se realizan estudios de neuro imágenes y electroencefalograma, no se encontraron alteraciones. Este es un diagnóstico de exclusión donde deben descartarse otras causas de defecto de fijación y movimientos cefálicos anómalos. En este momento con dos años de edad se constata una mejoría dada por disminución de las sacudidas cefálicas. Sin embargo, el retraso del desarrollo psicomotor, especialmente del lenguaje, sí puede requerir educación especial. Esta enfermedad es poco frecuente por lo que su detección temprana contribuye a un mejor pronóstico visual.The congenital ocular motor apraxia, also known as Cogan´s Syndrome, is a rare heredity disease that affects the eye in that to the extent that it can not move horizontally at will. Of unknown etiology, it was described by Cogan in 1952 and, classically considered as a sporadic disease with dominant autosomal heredity in some cases, and as an indicator of partial metabolic alterations or neurological development defects in others. An 8 month-old male patient was seen at the pediatric ophthalmology department. On the ocular motility exam, it was found that the child attempted to move his eyes towards an object that got his attention, but

  16. Anomalias congénitas e manifestações orais

    OpenAIRE

    Ribeiro, Raquel Costa

    2014-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária Introdução: As anomalias congénitas abrangem alterações de estrutura, função e metabolismo da criança. Resultantes de alterações físicas e /ou mentais, podendo estar presentes logo no nascimento ou manifestar-se mais tardiamente. Estima-se que 7,6 milhões de crianças ao nascimento sejam portadoras de uma anomalia congénita. ...

  17. Aplasia Cutis Congénita: Presentación de un caso

    Directory of Open Access Journals (Sweden)

    Rosa María Alonso Uría

    1998-06-01

    Full Text Available Se reportó el caso de un recién nacido, hijo de madre secundigesta, con una malformación congénita del cuero cabelludo, del tipo aplasia cutis congénita. Se describieron las características clínicas de ésta, su evolución, pronóstico y tratamiento. Se hizo énfasis en el cuidado y la prevención de las complicaciones, fundamentalmente infecciosas, en este tipo de neonatosThe case of a newborn, son of a secundigravida, with a congenital malformation of the scalp denominated aplasia cutis congenita is reported. Its clinical characteristics, evolutions, prognosis and treatment are described. Emphasis is made on the care and prevention of the complications, mainly infectious, in this type of neonates

  18. Trasplante cardiaco en pacientes adultos con cardiopatía congénita

    Directory of Open Access Journals (Sweden)

    Manel Tauron

    2017-11-01

    Full Text Available Resumen: Introducción y objetivos: Los pacientes adultos con cardiopatías congénitas representan un porcentaje pequeño del total de pacientes trasplantados de corazón. Tradicionalmente se ha asociado a este subgrupo de pacientes a una mayor mortalidad precoz. En nuestro centro hemos experimentado un incremento en el número de pacientes adultos con cardiopatía congénita remitidos para valoración de trasplante. Presentamos nuestra experiencia. Métodos: Entre mayo de 1984 y diciembre del 2014 se realizaron 508 trasplantes cardiacos. De ellos 16 (3% fueron en adultos con cardiopatía congénita. Se han analizado las características de este grupo, comparando su evolución con el resto de trasplantes de causa no congénita. Resultados: En el grupo de pacientes trasplantados con cardiopatía congénita la causa más frecuente fue la transposición completa de grandes vasos. Los pacientes congénitos trasplantados tuvieron una edad media inferior, menos factores de riesgo cardiovascular y mayor número de intervenciones previas que el grupo de trasplantados no congénitos, todas ellas diferencias estadísticamente significativas (p < 0,001 en todos los casos. La supervivencia de los trasplantados por cardiopatías congénitas fue del 87,5% (IC del 95%, 58,60%-96,72% al año, 78,6% (IC del 95%, 46,62%-92,79% a los 5 años y 57,4% (IC del 95%, 24,07-80,57% a los 10 años, sin diferencia (p = 0,23 respecto al grupo de no congénitos. Conclusiones: A pesar de que ha aumentado el número de pacientes con cardiopatías congénitas complejas remitidos a programas de trasplante cardiaco, continúan representando un porcentaje pequeño del total de trasplantes. Una minuciosa selección de pacientes candidatos, una buena planificación quirúrgica y un estricto control postoperatorio permiten disminuir la mortalidad precoz en los trasplantes de pacientes con cardiopatías congénitas complejas, haciéndola semejante a la de los pacientes

  19. TOKYO criteria 2014 for transpapillary biliary stenting.

    Science.gov (United States)

    Isayama, Hiroyuki; Hamada, Tsuyoshi; Yasuda, Ichiro; Itoi, Takao; Ryozawa, Shomei; Nakai, Yousuke; Kogure, Hirofumi; Koike, Kazuhiko

    2015-01-01

    It is difficult to carry out meta-analyses or to compare the results of different studies of biliary stents because there is no uniform evaluation method. Therefore, a standardized reporting system is required. We propose a new standardized system for reporting on biliary stents, the 'TOKYO criteria 2014', based on a consensus among Japanese pancreatobiliary endoscopists. Instead of stent occlusion, we use recurrent biliary obstruction, which includes occlusion and migration. The time to recurrent biliary obstruction was estimated using Kaplan-Meier analysis with the log-rank test. We can evaluate both plastic and self-expandable metallic stents (uncovered and covered). We also propose specification of the cause of recurrent biliary obstruction, identification of complications other than recurrent biliary obstruction, indication of severity, measures of technical and clinical success, and a standard for clinical care. Most importantly, the TOKYO criteria 2014 allow comparison of biliary stent quality across studies. Because blocked stents can be drained not only using transpapillary techniques but also by an endoscopic ultrasonography-guided transmural procedure, we should devise an evaluation method that includes transmural stenting in the near future. © 2014 The Authors. Digestive Endoscopy © 2014 Japan Gastroenterological Endoscopy Society.

  20. Caracterización de la sífilis congénita y gestacional en Caldas, Colombia

    OpenAIRE

    Agudelo Loaiza, Rubén Darío; Universidad Católica de Manizales; Medina Arredondo, Martha Cecilia; Cardona Rivas, Dora; Universidad Autónoma de Manizales

    2016-01-01

    Objetivo: Caracterizar el comportamiento de la sífilis congénita y gestacional en el departamento de Caldas durante el periodo 2009-2013 según las características socio demográficas y de la atención en salud del binomio madre-hijo con sífilis. Materiales y Método: Se realizó un estudio descriptivo de 71 casos de sífilis congénita y 316 casos de sífilis gestacional, reportados a través del sistema de vigilancia epidemiológica SIVIGILA. Resultados: El comportamiento de la sífilis congénita y ge...

  1. Tokyo XX videofestival ja kohtumine Suure Hiirega / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    1998-01-01

    JVC Tokyo XX videofestivalist. Peapreemia Jon Alpertile dokumentaalse videoga "Life of Crime : Deleris's Sad Story". R. Kelomehe videost "Maja". Interaktiivse kunsti muuseumist ICC (Inter Communication Center) Tokyo Opera Citys. Ilmunud ka kogumikus "Ekraan kui membraan". Tartu, 2007, lk. 72-75

  2. New international services and the competitiveness of Tokyo International Airport

    NARCIS (Netherlands)

    Lieshout, R.; Matsumoto, H.

    2012-01-01

    With the completion of Narita International Airport (Narita) in the Greater Tokyo Area, Tokyo International Airport (Haneda) was practically downgraded to a domestic airport. It lost its position as a key traffic hub for domestic to international air transport in Japan. Now the Japanese government

  3. Rehabilitación cardiaca en pacientes con cardiopatías congénitas

    OpenAIRE

    Úbeda Tikkanen, Ana

    2014-01-01

    Los avances médicos y quirúrgicos de los últimos años son responsables del aumento de la supervivencia de los pacientes con cardiopatías congénitas. Sin embargo este incremento de la longevidad de esta población, frecuentemente se acompaña de complicaciones e incluso secuelas, que repercutirán en su pronóstico vital y su calidad de vida. Los programas de Rehabilitación Cardiaca en cardiopatías adquiridas del adulto, están sólidamente estructurados, validados y ampliamente difundidos, habiend...

  4. Luxación congénita de cadera: nuestra experiencia

    OpenAIRE

    Saenz López de Rueda, F.; Lopez Vizcaya, F.

    1991-01-01

    La luxación congénita de cadera (L.C.C.) representa, aún hoy día, un auténtico problema dentro de la ortopedia infantil por su frecuencia y sobre todo por las secuelas invalidantes que un diagnóstico tardío puede condicionar. Basados en nuestra experiencia y revisión de un total de 334 casos, exponemos y valoramos los resultados obtenidos y propugnamos una íntima colaboración entre tocólogos, pediatras y ortopedas para evitar que la displasia luxante del recién nacido se transf...

  5. Cateterismo diagnóstico en cardiopatías congénitas del adulto

    OpenAIRE

    García Montes,José Antonio

    2006-01-01

    Los métodos no invasivos en la actualidad son de elección para el diagnóstico en pacientes adultos con cardiopatía congénita. La tendencia del cateterismo cardíaco en la actualidad es el tratamiento intervencionista de algunas cardiopatías, sin embargo, en algunos casos, sobre todo en cardiopatías complejas el cateterismo diagnóstico puede ser necesario como complemento de otros métodos no invasivos. La medición de presiones, toma de oximetrías y angiografías continúa siendo fundamental en el...

  6. Caso clínico-radiológico: sífilis congénita

    OpenAIRE

    F. Ximena Ortega, Dra.; B. Karla Moënne, Dra.; Dr. C. Mauricio Pinto; Dr. A. Salinas José; Dr. S. Stefan Hossiason; Dr. W. Fredy Ribert; Dr. M. Marcos Skarmeta

    2011-01-01

    La sífilis es una infección potencialmente devastadora en el recién nacido, cuya incidencia ha ido aumentando. Se presenta el caso de un prematuro que evoluciona con falla respiratoria y compromiso multisistémico precoz secundario a sífilis congénita. Se comentan hallazgos en el examen físico, laboratorio e imágenes. Se discute sobre las formas de presentación en el niño, pruebas diagnósticas y diagnóstico diferencial.

  7. APLASIA CUTIS CONGÉNITA – UM CASO CLÍNICO

    Directory of Open Access Journals (Sweden)

    Mónica Costeira

    2016-07-01

    Comentários: A aplasia cutis congénita é uma lesão que pode ser causadora de grande ansiedade parental, pelo que é importante ao Pediatra o seu reconhecimento e devido esclarecimento. Apesar de se tratar, na maioria das vezes, de um defeito benigno, é importante o conhecimento da sua relação com outras anomalias e síndromes de forma a otimizar a sua orientação precoce e adequada. Da mesma forma, é importante o aconselhamento genético, nos casos que assim o justifiquem.

  8. Ictiosis congénita tipo laminar, reporte de un caso.

    OpenAIRE

    Joaquín Saavedra D.; María José Sierralta S.; Cristian Saavedra D; Vanesa Rivera C; Francisco Cerda C.

    2014-01-01

    RESUMEN INTRODUCCIÓN: La ictiosis tipo laminar es una enfermedad dermatológica infrecuente perteneciente al grupo de las llamadas genodermatosis. Es una forma de ictiosis congénita que es evidente desde el nacimiento. PRESENTACIÓN DEL CASO: Recién nacido por cesárea, sexo masculino, de 36 semanas de gestación, adecuado para la edad gestacional y con APGAR 8. Antecedentes familiares: padres no consanguíneos y hermano con ictiosis tipo laminar. Luego de nacer es hospital...

  9. Diagnóstico prenatal de artrogriposis múltiple congénita Prenatal diagnosis of arthrogryposis multiplex congenita

    Directory of Open Access Journals (Sweden)

    Ivonne Martínez Vidal

    2013-03-01

    Full Text Available La artrogriposis múltiple congénita puede definirse como una displasia articular sistémica, caracterizada por rigidez articular en múltiples localizaciones de forma congénita. Se presenta un caso en el que se diagnosticó prenatalmente este signo clínico, que puede tener múltiples causas subyacentes.Arthrogryposis multiplex congenita may be defined as a systemic articular dysplasia characterized by articular rigidity in a many locations of congenital origin. A case was presented in which this clinical sign was diagnosed at prenatal phase and it may have many underlying causes.

  10. Urban climate in the Tokyo metropolitan area in Japan.

    Science.gov (United States)

    Matsumoto, Jun; Fujibe, Fumiaki; Takahashi, Hideo

    2017-09-01

    Long-term climate changes related with urbanization in Tokyo, Japan, and recent temperature and heavy rainfall distribution in the Tokyo metropolitan area are reviewed. A relatively high temperature increase in annual mean temperature at the rate of 3.0°C/century was detected in Tokyo for the period 1901-2015. Some observational evidence showed the existence of both thermal and mechanical effects of urbanization on recent heavy rainfall occurrences, and modeling studies also support precipitation enhancement. Urban influences were recognized in other climatological elements, such as number of fog days, relative humidity, and wind circulation. Copyright © 2017. Published by Elsevier B.V.

  11. Lõppes Moskva filmifestival / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    2005-01-01

    17.-26. juunil toimunud XXVII Moskva Rahvusvaheline Kinofestivali võitjad. Võitis Aleksei Utshiteli "Kosmos kui eelaimdus" ("Kosmos kak predtshuvstvije"), žürii eripreemia sai soomlane Aki Louhimies filmi "Paha maa" eest, parim režissöör oli taanlane Thomas Vinterberg filmiga "Dear Wendy"

  12. Prevención de la toxoplasmosis congénita en un hospital de Buenos Aires

    Directory of Open Access Journals (Sweden)

    Liliana Carral

    2013-06-01

    Full Text Available La prevención de la toxoplasmosis congénita se basa en la información de la mujer con medidas de prevención primaria, el diagnóstico serológico y el tratamiento de la embarazada y del niño. Se presentan los resultados de 12 años de implementación de un programa de prevención de la toxoplasmosis congénita, la tasa de madres infectadas, de transmisión vertical, de niños infectados y la gravedad de la afección causada. Se realizó un estudio observacional prospectivo sobre 12 035 gestantes atendidas en la maternidad del Hospital Alemán de Buenos Aires entre enero de 2000 y diciembre de 2011. Se observó una prevalencia de anticuerpos anti Toxoplasma gondii de 18.33% (2 206/12 035. Treinta y siete mujeres de 9 792 susceptibles tuvieron infección aguda, la tasa de incidencia de infección materna fue de 3.78 por 1 000 nacimientos. La tasa de transmisión transplacentaria de la infección fue 5.4% (2/37. Dos recién nacidos tuvieron toxoplasmosis congénita, uno no tuvo signos clínicos y el otro presentó coriorretinitis y estrabismo. Recibieron tratamiento 35 madres y los 2 niños con toxoplasmosis congénita. En conclusión: Las cifras de transmisión obtenida permiten considerar a este programa de prevención como un recurso válido para minimizar el impacto de la toxoplasmosis congénita.

  13. Pilot fatigue : intercontinental jet flight. 1. Oklahoma City Tokyo.

    Science.gov (United States)

    1965-03-01

    Following 3 consecutive days of biomedical assessment in Oklahoma City, six healthy subjects were transported to Tokyo, where assessments were made on alternate days throughout a period of 10 days, and were then transported back to Oklahoma City, whe...

  14. Consenso argentino de toxoplasmosis congénita Argentine Consensus of Congenital Toxoplasmosis

    Directory of Open Access Journals (Sweden)

    Ricardo Durlach

    2008-02-01

    Full Text Available La transmisión de la infección por Toxoplasma gondii de la madre al hijo ocurre cuando la madre se infecta por primera vez en el transcurso del embarazo. Tanto el diagnóstico prenatal, como el del primer año de vida se basa en pruebas serológicas; y la mayoría de las veces es necesario realizar más de una de estas pruebas ya que tienen distintos porcentajes de sensibilidad y/o especificidad así como distintos niveles de complejidad. El recién nacido requiere seguimiento serológico en el primer año de vida o hasta que se descarte el diagnóstico de toxoplasmosis congénita. El diagnóstico temprano de la infección, en la mujer embarazada, permite un tratamiento oportuno y se indica con el propósito de reducir la tasa de transmisión y el daño congénito. Es posible que con un programa activo, de prevención y tratamiento temprano, se pueda reducir la tasa de incidencia de la toxoplasmosis congénita de alrededor del 5 por mil nacimientos a 0.5 por mil. El objetivo de este consenso fue revisar la literatura científica para la prevención, el diagnóstico y el tratamiento de la toxoplasmosis congénita, para que se pueda implementar en nuestro país.The mother-to-child transmission in Toxoplasma gondii infection occurs only when the infection is acquired for the first time during pregnancy. The prenatal and early postnatal diagnosis can only be achieved by serological testing. Serologic tests have different sensitivities, specificities and complexities, so that different tests in more than one blood sample are necessary for the diagnosis. Serological follow-up of the infants should be conducted during the first year of life or until the diagnosis of congenital toxoplasmosis can be ruled out. Treatment recommendations try to reduce the transmission rate and the risk of congenital damage. Congenital toxoplasmosis incidence rate is approximately 5 per 1000 births, but can be reduced to 0.5 per 1000 with an active screening program. The

  15. Food poisoning outbreak in Tokyo, Japan caused by Staphylococcus argenteus.

    Science.gov (United States)

    Suzuki, Yasunori; Kubota, Hiroaki; Ono, Hisaya K; Kobayashi, Makiko; Murauchi, Konomi; Kato, Rei; Hirai, Akihiko; Sadamasu, Kenji

    2017-12-04

    Staphylococcus argenteus is a novel species subdivided from Staphylococcus aureus. Whether this species can cause food poisoning outbreaks is unknown. This study aimed to investigate the enterotoxigenic activities of two food poisoning isolates suspected to be S. argenteus (Tokyo13064 and Tokyo13069). The results for phylogenic trees, constructed via whole genome sequencing, demonstrated that both isolates were more similar to a type strain of S. argenteus (MSHR1132) than any S. aureus strain. Moreover, the representative characteristics of S. argenteus were present in both strains, namely both isolates belong to the CC75 lineage and both lack a crtOPQMN operon. Thus, both were determined to be "S. argenteus." The compositions of the two isolates' accessory elements differed from those of MSHR1132. For example, the seb-related Staphylococcus aureus pathogenicity island, SaPIishikawa11, was detected in Tokyo13064 and Tokyo13069 but not in MSHR1132. Both isolates were suggested to belong to distinct lineages that branched off from MSHR1132 lineages in terms of accessory elements. Tokyo13064 and Tokyo13069 expressed high levels of s(arg)eb and produced S(arg)EB protein, indicating that both have the ability to cause food poisoning. Our findings suggest that S. argenteus harboring particular accessory elements can cause staphylococcal diseases such as food poisoning, similarly to S. aureus. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Síndrome de hipoventilación alveolar central congénita

    OpenAIRE

    Edwin Hernando Herrera-Flores; Alfredo Rodríguez-Tejada; Martha Margarita Reyes-Zúñiga; Martha Guadalupe Torres-Fraga; Armando Castorena-Maldonado; José Luis Carrillo-Alduenda

    2015-01-01

    Introducción: El síndrome de hipoventilación alveolar central congénita (SHACC) es un raro trastorno respiratorio del dormir, aunque cada vez más frecuentemente diagnosticado en clínicas de sueño y servicios de neumología pediátrica. Si bien se desconoce su epidemiología, en la literatura médica existen cerca de 300 casos reportados, y su incidencia es de 1 caso por cada 200,000 recién nacidos vivos. Se caracteriza por hipoventilación alveolar que se presenta o empeora durante el sueño. Es se...

  17. Vena cava superior izquierda persistente asociada con cardiopatías congénitas

    Directory of Open Access Journals (Sweden)

    Florentino J. Vargas

    2008-01-01

    Full Text Available La persistencia de la vena cava superior izquierda asociada con cardiopatías congénitas suele ser un hallazgo benigno, sin repercusión hemodinámica ni quirúrgica. Sin embargo, en ocasiones su presencia puede constituir una entidad fisiopatológica que requiere tratamiento o conducir a modificaciones en las técnicas quirúrgicas utilizadas para otras malformaciones. Estas situaciones en las que la presencia de la vena cava superior izquierda requiere un abordaje quirúrgico específico son motivo de revisión en el presente trabajo. Asimismo, se comenta una técnica quirúrgica original utilizada en estos pacientes, y recientemente comunicada por nuestro grupo, en relación con cada una de las diferentes presentaciones anatómicas.

  18. Reporte de segundo caso en Cuba de clorhidrorrea congénita

    Directory of Open Access Journals (Sweden)

    José Purón Barreras

    Full Text Available La clorhidrorrea congénita es un raro desorden autosómico recesivo, causado por un defecto en el intercambio de cloruro/bicarbonato en el íleon y colon. En este trabajo se reporta el caso de un niño de 1 año de edad con características patognomónicas de esta condición, consistentes en antecedentes prenatales de polihidramnios, diarreas acuosas desde el nacimiento, poca ganancia de peso, alcalosis metabólica y deshidratación. El diagnóstico fue confirmado por el elevado contenido de cloruro en heces, y es el segundo caso reportado en la literatura cubana.

  19. Hipertensión pulmonar en cardiopatías congénitas del adulto

    OpenAIRE

    Luz Adriana Ocampo-Aristizábal; Margarita María Zapata-Sánchez; Luis Horacio Díaz-Medina; Rafael Lince-Varela

    2017-01-01

    La hipertensión arterial pulmonar se encuentra comúnmente en adultos con cardiopatías congénitas. De acuerdo con el tipo de defecto, el momento de la corrección y la repercusión hemodinámica será la magnitud del compromiso y a su vez, un determinante esencial en la posibilidad de realizar manejo correctivo en aquellos pacientes diagnosticados de manera tardía. Se hizo una revisión de la información disponible en cuanto a la clasificación, el diagnóstico y el manejo de acuerdo con la posibilid...

  20. Catarata congénita: actualización Congenital cataract: updating

    Directory of Open Access Journals (Sweden)

    Lourdes R Hernández Santos

    2004-06-01

    Full Text Available Se realizó una revisión del tema relacionado con la catarata congénita, enfermedad que constituye la primera causa de baja visión y la segunda causa de ceguera en Cuba. Se presenta su diagnóstico, antecedentes, clasificación, las características clínicas, entre otras. Además, los principios y técnicas quirúrgicas, complicaciones posquirúrgicas encontradas, así como su pronósticoA review of the topic on congenital cataract, which is the first cause of low vision and the second cause of blindness in Cuba, was made. Its diagnosis, antecedents, classification, clinical characteristics, postsurgical complications found, as well as its prognosis, are presented

  1. Extrofia vesical, una anomalía congénita

    OpenAIRE

    Roger Rojas Rojas; Madelín Escobar Pupo; Marbelis Betancourt Gavilán; Marilyn Núñez Rodríguez

    2015-01-01

    Se realizó un trabajo descriptivo y representativo de un caso, para el que se utilizó la entrevista, la ultrasonografía y la evaluación del grupo Multidisciplinario de Genética Provincial. La paciente con 23 años de edad, con historia obstetricia de G2 P1 eutócico, clasificado de riesgo genético bajo, se le detectó en el ultrasonido del segundo semestre en la semana de gestación 19.6 una anomalía congénita, diagnosticada como extrofia vesical. Después de encontrado este hallazgo, la gestante ...

  2. Brida intestinal congénita Congenital bridle present in intestines

    Directory of Open Access Journals (Sweden)

    Angelicia Crespo Campos

    2009-06-01

    Full Text Available La obstrucción congénita del tubo digestivo es una de las patologías quirúrgicas neonatales más frecuentes. Se presenta el caso de un recién nacido que, a las 30 h de vida, aún sin evacuar meconio, comenzó con vómitos biliosos, distensión abdominal, irritabilidad y disminución de los ruidos hidroaéreos. Tras valoración conjunta con otras especialidades y los estudios correspondientes, se decidió la intervención quirúrgica de urgencia. Se encontró brida congénita a nivel del íleon terminal que acodaba el intestino y permitía el paso incompleto del contenido fecal. La evolución fue satisfactoria, sin complicaciones, y se dio el alta a los 17 días. Se ofrece una revisión actualizada sobre el tema y se incluyen fotografías del caso.Congenital obstruction of digestive tract is one of the more frequent neonatal surgical pathologies. Authors present the case of a newborn that at 30 hrs of life, even without meconium evacuation, had bilious vomiting, abdominal distention, irritability, and decrease of hydro-aerial bruits. After a combined assessment with other specialties and the corresponding studies, we decided to perform an emergence surgical intervention. A congenital bridle was found at level of terminal ileum with an elbowed intestine allowing the incomplete passage of fecal content. The course was satisfactory without complications and discharged at 17 days. Authors offer an updating review on matter including photographies of the case.

  3. Cirugía de las arritmias en las cardiopatías congénitas

    Directory of Open Access Journals (Sweden)

    Fernando Hornero

    2008-10-01

    Full Text Available La propia fisiopatología de las cardiopatías congénitas y el impacto de algunas correcciones quirúrgicas pueden predisponer al desarrollo de arritmias cardíacas, que incluyen taquicardia supraventricular macrorreentrante, flutter, fibrilación auricular, taquicardia auricular ectópica, taquicardia ventricular, síndrome del seno enfermo, bloqueo auriculoventricular y muerte súbita, entre otras. En la actualidad el tratamiento definitivo de estas arritmias y su profilaxis durante la corrección quirúrgica son procesos eficaces, con baja morbilidad y gran beneficio clínico para el paciente. En este trabajo se revisa el estado actual del tratamiento quirúrgico de las arritmias en las cardiopatías congénitas.

  4. A new probabilistic seismic hazard assessment for greater Tokyo

    Science.gov (United States)

    Stein, R.S.; Toda, S.; Parsons, T.; Grunewald, E.; Blong, R.; Sparks, S.; Shah, H.; Kennedy, J.

    2006-01-01

    Tokyo and its outlying cities are home to one-quarter of Japan's 127 million people. Highly destructive earthquakes struck the capital in 1703, 1855 and 1923, the last of which took 105 000 lives. Fuelled by greater Tokyo's rich seismological record, but challenged by its magnificent complexity, our joint Japanese-US group carried out a new study of the capital's earthquake hazards. We used the prehistoric record of great earthquakes preserved by uplifted marine terraces and tsunami deposits (17 M???8 shocks in the past 7000 years), a newly digitized dataset of historical shaking (10 000 observations in the past 400 years), the dense modern seismic network (300 000 earthquakes in the past 30 years), and Japan's GeoNet array (150 GPS vectors in the past 10 years) to reinterpret the tectonic structure, identify active faults and their slip rates and estimate their earthquake frequency. We propose that a dislodged fragment of the Pacific plate is jammed between the Pacific, Philippine Sea and Eurasian plates beneath the Kanto plain on which Tokyo sits. We suggest that the Kanto fragment controls much of Tokyo's seismic behaviour for large earthquakes, including the damaging 1855 M???7.3 Ansei-Edo shock. On the basis of the frequency of earthquakes beneath greater Tokyo, events with magnitude and location similar to the M??? 7.3 Ansei-Edo event have a ca 20% likelihood in an average 30 year period. In contrast, our renewal (time-dependent) probability for the great M??? 7.9 plate boundary shocks such as struck in 1923 and 1703 is 0.5% for the next 30 years, with a time-averaged 30 year probability of ca 10%. The resulting net likelihood for severe shaking (ca 0.9g peak ground acceleration (PGA)) in Tokyo, Kawasaki and Yokohama for the next 30 years is ca 30%. The long historical record in Kanto also affords a rare opportunity to calculate the probability of shaking in an alternative manner exclusively from intensity observations. This approach permits robust estimates

  5. Assessment of flood risk in Tokyo metropolitan area

    Science.gov (United States)

    Hirano, J.; Dairaku, K.

    2013-12-01

    Flood is one of the most significant natural hazards in Japan. The Tokyo metropolitan area has been affected by several large flood disasters. Therefore, investigating potential flood risk in Tokyo metropolitan area is important for development of adaptation strategy for future climate change. We aim to develop a method for evaluating flood risk in Tokyo Metropolitan area by considering effect of historical land use and land cover change, socio-economic change, and climatic change. Ministry of land, infrastructure, transport and tourism in Japan published 'Statistics of flood', which contains data for flood causes, number of damaged houses, area of wetted surface, and total amount of damage for each flood at small municipal level. By using these flood data, we estimated damage by inundation inside a levee for each prefecture based on a statistical method. On the basis of estimated damage, we developed flood risk curves in the Tokyo metropolitan area, representing relationship between damage and exceedance probability of flood for the period 1976-2008 for each prefecture. Based on the flood risk curve, we attempted evaluate potential flood risk in the Tokyo metropolitan area and clarify the cause for regional difference of flood risk. By analyzing flood risk curves, we found out regional differences of flood risk. We identified high flood risk in Tokyo and Saitama prefecture. On the other hand, flood risk was relatively low in Ibaraki and Chiba prefecture. We found that these regional differences of flood risk can be attributed to spatial distribution of entire property value and ratio of damaged housing units in each prefecture.We also attempted to evaluate influence of climate change on potential flood risk by considering variation of precipitation amount and precipitation intensity in the Tokyo metropolitan area. Results shows that we can evaluate potential impact of precipitation change on flood risk with high accuracy by using our methodology. Acknowledgments

  6. Enhanced Surveillance for the Sports Festival in Tokyo 2013: Preparation for the Tokyo 2020 Olympic and Paralympic Games.

    Science.gov (United States)

    Shimatani, Naotaka; Sugishita, Yoshiyuki; Sugawara, Tamie; Nakamura, Yuuki; Ohkusa, Yasushi; Yamagishi, Takuya; Matsui, Tamano; Kawano, Masashi; Watase, Hirotoshi; Morikawa, Yukiko; Oishi, Kazunori

    2015-01-01

    Enhanced surveillance was conducted during the Sports Festival in Tokyo 2013 (September 28-October 14, 2013) for early detection of outbreaks of infectious diseases and other health emergencies. Through this enhanced surveillance, 15 cases were found that required additional gathering of information outside the routine process of creating/evaluating the Daily Report. However, none of these was assessed as critical. Through the enhanced surveillance, we structured a framework that allows for earlier response when detecting aberrations. It includes the role of the Tokyo Metropolitan Government in communications and contacts with relevant parties such as public health centers, as well as in monitoring of surveillance data. However, some issues need to be further considered toward the Tokyo 2020 Olympic and Paralympic Games, such as establishing the criteria for additional response steps, increasing the number of participating bodies in syndromic surveillance, and strengthening of cooperation with related departments, including those for crisis management assuming potential biological/chemical terrorism.

  7. Malformaciones Cerebrales Congénitas. Pronóstico Inesperado

    Directory of Open Access Journals (Sweden)

    Tomás Omar Zamora Bastidas

    2013-09-01

    Full Text Available La Hemihidranencefalia es una enfermedad congénita cerebral grave y relativamente rara caracterizada por la ausencia unilateral completa o casi total de la corteza cerebral dentro de un cráneo normal con preservación de estructuras como las meninges, ganglios basales, cerebelo, protuberancia, bulbo raquídeo y la hoz cerebral. Los hemisferios cerebrales inicialmente toman la forma normal y luego se plantea que más tarde se da una destrucción cortical por un grave proceso encefaloclástico, en particular por una lesión focal hipóxico-isquémica, lo cual lleva a que el lugar que ocupaba el tejido destruido sea sustituido en gran parte por espacios llenos de líquido cefalorraquídeo que se asemeja a un gran quiste intracraneal. Se presentan dos casos clínicos, el primero con una hemihidranancefalia derecha con un pronóstico desfavorable desde el momento del diagnóstico, no obstante actualmente ha alcanzado un desarrollo cognitivo que rebasa las expectativas para su condición; El segundo caso es un paciente con hidranencefalia global, éste no alcanzó un desarrollo cognitivo aceptable, pero contradijo el pronóstico y tiempo de vida acorde con su grave malformación.

  8. Microcalcificaciones cerebrales en un recién nacido con tuberculosis congénita

    Directory of Open Access Journals (Sweden)

    Yolanda Cifuentes

    2016-03-01

    Se presenta el caso de un recién nacido en tratamiento para sífilis congénita que presentó microcalcificaciones detectadas en una ecografía transfontanelar, lo que alertó sobre la existencia de otro agente infeccioso. La prueba de PCR fue negativa para citomegalovirus, así como los títulos de IgM para toxoplasma, rubéola y herpes I y II. Dado el antecedente de un tratamiento incompleto para tuberculosis en la mujer gestante, se sospechó la presencia de infección por el bacilo de la tuberculosis. No se encontraron bacilos ácido-alcohol resistentes en tres muestras de jugo gástrico, y la prueba de PCR-IS6110 fue positiva en líquido cefalorraquídeo y en orina, pero no en sangre. El recién nacido recibió tratamiento con penicilina cristalina durante 10 días, así como con isoniacida, rifampicina, pirazinamida y estreptomicina. Actualmente se le hace seguimiento clínico.

  9. Prevalencia de los factores de riesgo para toxoplasmosis congénita en maternas

    Directory of Open Access Journals (Sweden)

    Yolanda Torres de Galvis

    2001-04-01

    Full Text Available

    La toxoplasmosis a pesar de no ser una causa frecuente de infección en la gestante, sí constituye un factor de riesgo para el binomio madre-hijo. En nuestro medio la incapacidad para hacer un diagnóstico prenatal precoz y específico es muy grande debido a los costos; por lo tanto, la estrategia para disminuir este problema es principalmente la prevención. La toxoplasmosis congénita adquiere importancia cuando ocurre como primoinfección en la mujer embarazada, ocasionando anormalidades fetales. Los principales factores de riesgo están asociados a la convivencia con felinos.
    En la ciudad de Medellín se han desarrollado dos estudios sobre el
    tema: uno en el sector oficial con prevalencia de infección en gestantes del 38% (610 mujeres, y el segundo una encuesta en Susalud con 200 mujeres maternas en el que se encontró que el 86% de ellas desconocían la enfermedad, un 14.5% convivían con gatos, y el 27.6% comían carne mal cocida.

     

  10. Manejo clinicoquirúrgico de la anoftalmia y de la microftalmia congénitas

    Directory of Open Access Journals (Sweden)

    Irene Rojas Rondón

    Full Text Available La anoftalmia y la microftalmia congénitas son defectos oculares poco frecuentes, generalmente identificados en el momento del nacimiento, como resultado de alteraciones en la organogénesis del ojo a consecuencia de la acción de factores genéticos y ambientales durante el desarrollo embrionario. Estas anomalías provocan grave discapacidad visual a las personas que la padecen, por lo que generan gran repercusión en el ámbito psicosocial. El diagnóstico y el tratamiento precoz permitirán la estimulación visual a edad temprana, la corrección parcial o total de la anomalía y una mejor calidad de vida de estos pacientes, aun cuando no sea posible evitar la ceguera. La conducta ante estas afecciones es compleja y controversial; constituyen un reto para el cirujano oculoplástico y para el protesista. Por esta razón se decide realizar una revisión bibliográfica para profundizar en el adecuado manejo clinicoquirúrgico de estas anomalías.

  11. No todo es zika: toxoplasmosis congénita, ¿aún prevalente en Colombia?

    Directory of Open Access Journals (Sweden)

    Jorge L Alvarado-Socarras

    Full Text Available La toxoplasmosis congénita continúa siendo un problema de salud pública. Aun existiendo guías plenamente divulgadas y conocidas, se observa poca implementación de las mismas y falta de adecuada interpretación de pruebas serológicas en gestantes Esto puede generar falta de captación y tratamiento en embarazadas con primoinfección por Toxoplasma gondii. Reportamos una serie de casos, con compromiso neurológico y sistémico (dificultad respiratoria, hepatoesplenomegalia, enterocolitis, calcificaciones cerebrales, trombocitopenia, corioretinis, ascitis, choque. Si bien el virus de Zika causó epidemia en 2015-2016 en Brasil, Colombia y otros países, toxoplasmosis es un diagnóstico diferencial aún prevalente en estos países, con secuelas graves, discapacidad neurológica y riesgo de daño ocular, incluso tardío. Adicionalmente, existen algunas variedades de cepas de T. gondii con comportamiento más agresivo en Latinoamérica, lo cual empeora la presentación de los casos, incluyendo además mayor riesgo de muerte.

  12. Extrofia vesical, una anomalía congénita

    Directory of Open Access Journals (Sweden)

    Roger Rojas Rojas

    2015-12-01

    Full Text Available Se realizó un trabajo descriptivo y representativo de un caso, para el que se utilizó la entrevista, la ultrasonografía y la evaluación del grupo Multidisciplinario de Genética Provincial. La paciente con 23 años de edad, con historia obstetricia de G2 P1 eutócico, clasificado de riesgo genético bajo, se le detectó en el ultrasonido del segundo semestre en la semana de gestación 19.6 una anomalía congénita, diagnosticada como extrofia vesical. Después de encontrado este hallazgo, la gestante fue remitida al Centro Genético Provincial. El equipo facultativo evaluó el caso y decidió la interrupción electiva del embarazo, siendo un feto de 450 gramos del sexo femenino. El resultado final de la anatomía patológica fue: ausencia de fusión del hueso pelviano; malformación de la vulva, clítoris prominente, labios mayores cortos y abiertos; vejiga insertada en la pared abdominal.

  13. Pariisi Tokyo palee taassünd / Merike Trubert

    Index Scriptorium Estoniae

    Trubert, Merike

    2002-01-01

    21. I avati Pariisis taas Tokyo palee, nüüdsest kaasaegse kunsti eksponeerimiseks. Kunstikriitikutest direktorid Nicolas Bourriaud ja Jérõme Sans on seadnud eesmärgiks avastada uusi talente. Pakuti vaadata Alexander Györfi filmi "Ballaad õnnelikest inimestest", mida reaalsuses ei eksisteeri jm

  14. Sounding moves: flamenco, gender, and meaning in Tokyo

    NARCIS (Netherlands)

    van Ede, Y.; Dunin, E.I.; Stavělová, D.; Gremlicová, D.

    2012-01-01

    This paper addresses the complex interactions between gender and localization of a world dance by focusing on the signification strategies of flamenco dance in Tokyo, Japan. Key in understanding these strategies are the senses. Sensory structures are the cultural incentive; embedded in local

  15. Teachers' Perceptions of School Libraries: Comparisons from Tokyo and Honolulu.

    Science.gov (United States)

    Nakamura, Yuriko

    2000-01-01

    Discusses and compares results of a survey of teacher's perceptions of school libraries in Tokyo, Japan and in Honolulu, Hawaii that showed differences in policies, availability of trained school library personnel, and in the nature of school library development. Copies of the questionnaires used are appended. (Author/LRW)

  16. International Family Profiles and Parental School Choice in Tokyo

    Science.gov (United States)

    Velliaris, Donna M.; Willis, Craig R.

    2014-01-01

    The concept of being an "international" citizen is one that describes an increasing number of people worldwide. This has implications for the educational experiences of many students, which can be reflected in the school choices made by their parents. As part of this study, "international" parents residing in Tokyo were…

  17. Tokyo Guidelines 2018: management bundles for acute cholangitis and cholecystitis

    NARCIS (Netherlands)

    Mayumi, Toshihiko; Okamoto, Kohji; Takada, Tadahiro; Strasberg, Steven M.; Solomkin, Joseph S.; Schlossberg, David; Pitt, Henry A.; Yoshida, Masahiro; Gomi, Harumi; Miura, Fumihiko; Garden, O. James; Kiriyama, Seiki; Yokoe, Masamichi; Endo, Itaru; Asbun, Horacio J.; Iwashita, Yukio; Hibi, Taizo; Umezawa, Akiko; Suzuki, Kenji; Itoi, Takao; Hata, Jiro; Han, Ho-Seong; Hwang, Tsann-Long; Dervenis, Christos; Asai, Koji; Mori, Yasuhisa; Huang, Wayne Shih-Wei; Belli, Giulio; Mukai, Shuntaro; Jagannath, Palepu; Cherqui, Daniel; Kozaka, Kazuto; Baron, Todd H.; de Santibañes, Eduardo; Higuchi, Ryota; Wada, Keita; Gouma, Dirk J.; Deziel, Daniel J.; Liau, Kui-Hin; Wakabayashi, Go; Padbury, Robert; Jonas, Eduard; Supe, Avinash Nivritti; Singh, Harjit; Gabata, Toshifumi; Chan, Angus C. W.; Lau, Wan Yee; Fan, Sheung Tat; Chen, Miin-Fu; Ker, Chen-Guo; Yoon, Yoo-Seok; Choi, In-Seok; Kim, Myung-Hwan; Yoon, Dong-Sup; Kitano, Seigo; Inomata, Masafumi; Hirata, Koichi; Inui, Kazuo; Sumiyama, Yoshinobu; Yamamoto, Masakazu

    2018-01-01

    Management bundles that define items or procedures strongly recommended in clinical practice have been used in many guidelines in recent years. Application of these bundles facilitates the adaptation of guidelines and helps improve the prognosis of target diseases. In Tokyo Guidelines 2013 (TG13),

  18. Supermodernity, distraction, schizophrenia: walking in Tokyo & Hong Kong.

    Directory of Open Access Journals (Sweden)

    Ian Ho-Yin Fong

    2014-12-01

    Full Text Available The architecture in a supermodern city has no sense of the place where it is located. This paper discusses how schizophrenia and distraction, through walking, respond to supermodernity by referring to how three dislocated subjects, Fumiya Takemura, Aiichiro Fukuhara and Fai in Tokyo and Hong Kong, are respectively depicted in the novel, Adrift in Tokyo written by Fujita Yoshinaga in 1999, with a film adaptation by Satoshi Miki (2007, and the film To Live and Die in Mongkok directed by Wong Jing in 2009. It suggests that Hong Kong is more supermodern than Tokyo. After his release from prison, Fai in To Live and Die in Mongkok finds that Mongkok is a completely different place from the one in which he used to live. The living conditions are no better than those in the prison. He hallucinates about the past. Adrift in Tokyo can be read as a story about walking. Fukuhara, a debt collector, killed his wife; before surrendering to the police, he orders his debtor, Takemura, to walk with him in Tokyo in order to re-experience the walks he enjoyed with his wife. If Takemura agrees, the debt can be paid off. This paper discusses how the repressed heterogeneous time and place can be approached by walking in a way that the rhythm of life can be (re-experienced; in other words, when the body moves forward physically, the past appears as specter haunting the walker. This paper discusses how Adrift in Tokyo and To Live and Die in Mongkok read cities in distractive and schizophrenic ways. In the film version of Adrift in Tokyo, Takemura’s failed relationship with his father may unconsciously drive him to walk with Fukuhara. The novel may imply that the lost relationship with his mother drives him to walk. The film and the novel both address a kind of locality which should be inseparable from the birth parents. To Live and Die in Mongkok suggests that supermodernity kills mother and father. The Father-son relationship disappears at the very beginning of the

  19. Cirugía de las taquiarritmias en las cardiopatías congénitas

    OpenAIRE

    Manuel Pérez; José María Caffarena

    2010-01-01

    Nuevas técnicas quirúrgicas en las cardiopatías congénitas (CC) y avances en su manejo postoperatorio han mejorado en la actualidad las expectativas de vida de estos pacientes, y con ello mayor probabilidad de reintervenciones a lo largo de la evolución. En estos pacientes una de las complicaciones más frecuentes son las arritmias. En este capítulo vamos a resumir las arritmias más frecuentes entre las CC y su manejo quirúrgico.

  20. Eficacia de los estiramientos como tratamiento de la tortícolis muscular congénita

    OpenAIRE

    García Domínguez, Elsa

    2016-01-01

    La tortícolis muscular congénita (TMC) es una deformidad que se detecta al nacer o poco después del nacimiento. Se caracteriza por la flexión lateral o inclinación de la cabeza hacia un lado y la rotación cervical hacia el otro lado como consecuencia del acortamiento y engrosamiento unilateral o contracción excesiva del músculo esternocleidomastoideo (ECM). Esto produce una limitación de la amplitud de movimiento, tanto en rotación como en flexión lateral y también hay un desequilibrio de la ...

  1. Fibrosis unilateral congénita con enoftalmo y ptosis Congenital unilateral fibrosis with enophthalmos and ptosis

    OpenAIRE

    Yaimir Estévez Miranda; Rosa Maria Naranjo Fernández; Teresita de Jesús Méndez Sánchez; Raúl Rúa Martínez

    2011-01-01

    El síndrome de fibrosis congénita es definido como un grupo de desórdenes congénitos raros caracterizado por la restricción de los músculos extraoculares y el reemplazo de los músculos por el tejido fibroso. Muchos autores utilizan la clasificación en la que se manifiesta en cinco tipos diferentes. El caso que se presenta corresponde a un niño quien desde el nacimiento está imposibilitado de elevar su ojo izquierdo. Al examen oftalmológico resultó positivo una ptosis palpebral en su ojo izqui...

  2. Colesteatoma do canal auditivo externo em atrésia aural congénita : caso clínico

    OpenAIRE

    Pinto, Ana Sofia Borges Garrido Vaz

    2016-01-01

    Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2016 A estenose congénita do canal auditivo externo faz parte do espectro da atrésia aural e pode estar associada ao desenvolvimento de colestea toma do canal auditivo externo (CAE) . Apresenta - se um caso de colesteatoma do CAE num doente com atrésia aural bilateral, completa no ouvido direito e com cana l auditivo residual à esquerda, integradas na Síndrome de Goldenhar. Acompanhado...

  3. [Phylogenetic analysis of rabies viruses isolated from animals in Tokyo in the 1950s].

    Science.gov (United States)

    Hatakeyama, Kaoru; Sadamasu, Kenji; Kai, Akemi

    2011-05-01

    Molecular epidemiological analysis of 96 rabies viruses isolated from animals in Tokyo in the 1950s involves Japanese fixed virus, Komatsugawa, Takamen, and Nishigahara strains. Strains isolated in Tokyo were divided into Tokyo 1 and Tokyo 2, and grouped into a worldwide distribution cluster differing from Takamen and Nishigahara. Tokyo 1 was grouped into the same cluster as viruses isolated from United States west coast dogs in the 1930s and 1940s. Tokyo 2 was grouped into the same cluster as the Komatsugawa strain, also known as a cluster of viruses from the Khabarovsk raccoon dog, and the Lake Baikal stepped fox in Russia. These findings suggest that 1950s Tokyo rabies viruses were related to those in Russia and the USA.

  4. IMPACTO ECONÓMICO DE LA PREMATUREZ Y LAS MALFORMACIONES CONGÉNITAS SOBRE EL COSTO DE LA ATENCIÓN NEONATAL

    OpenAIRE

    Salinas P,Hugo; Albornoz V,Jaime; Erazo B,Marcia; Catalán M,Jorge; Hübner G,María Eugenia; Preisler R,Jessica; Juárez H,M. Eugenia; Ide V,Rodolfo; Carmona G,Sergio; Fernández B,Manuela

    2006-01-01

    Objetivos: Calcular los costos de la atención neonatal de recién nacidos prematuros y en portadores de malformaciones congénitas mayores compatibles con la vida. Pacientes y Método: Estudio retrospectivo efectuado en el Departamento de Ginecología y Obstetricia del Hospital Clínico de la Universidad de Chile, en 82 recién nacidos menores de 34 semanas de gestación y en 14 con malformaciones congénitas mayores, de más de 37 semanas de gestación, compatibles con la vida, atendidos entre enero y...

  5. Manejo estomatológico del paciente pediátrico con cardiopatía congénita. Revisión de la literatura

    OpenAIRE

    Zavala Cornejo, Karla Berenice; Práctica privada, Uruapan Michoacán, México; Vinitzky Brener, Ilan; Universidad Tecnológica de México (Unitec), México; Ramírez Bouchan, Daniel; Hospital del Niño y la Mujer, San Luis Potosí, México

    2011-01-01

    Las cardiopatías congénitas se definen como lesiones anatómicas del corazón y sus componentes que se presentan en el nacimiento y representan un problema de salud pública de primer orden. Los pacientes afectados presentan sintomatología muy diversa y requieren un manejo estomatológico adecuado y de calidad que les permita mantener su salud bucal sin poner en riesgo su salud general. Existe muy poca literatura sobre el manejo estomatológico del paciente pediátrico con cardiopatía congénita, po...

  6. Oximetría de pulso en el pesquisaje de malformaciones congénitas cardiovasculares en recién nacidos

    OpenAIRE

    Burgos Quiroga, Ana Gabriela; Caicedo Freire, María Lissette; Toledo Santana, Nancy; Marín Pérez, Alfredo; Marín Toledo, Ilien; Ramírez Fernández, Juan Antonio

    2017-01-01

    Las malformaciones congénitas cardiovasculares son anomalías del desarrollo estructural del corazón que ocurren en el período embrionario y son una de las principales causas de morbimortalidad infantil. Sus manifestaciones clínicas suelen ser tardías por los cambios circulatorios que existen durante el paso a la vida extrauterina. La oximetría de pulso es un método de detección precoz de cardiopatías congénitas, considerada una herramienta capaz de detectar grados de hipoxemia leve que la exp...

  7. A new probabilistic seismic hazard assessment for greater Tokyo

    Science.gov (United States)

    Stein, R.; Toda, S.; Parsons, T.; Grunewald, E.

    2006-12-01

    Tokyo and its outlying cities are home to one-quarter of Japan's 127 million people. Highly destructive earthquakes struck the capital in 1703, 1855 and 1923, the last of which took 105,000 lives. Unlike California's seismic environment of shallow and largely strike-slip faults, Tokyo lies 200 km from a triple junction with two subduction zones, and 80 km from a front of active volcanoes. Further, some of the region's megathust faults are seismically coupled, some undergo episodic slip events, and others appear to be permanently aseismic. To reinterpret the tectonic structure, identify active faults and their slip rates, and estimate their earthquake frequency, we analyzed the 7,000-yr record of seventeen M~8 shocks preserved by uplifted marine terraces and tsunami deposits, and 150 GPS vectors in the past 10 years from Japan's GeoNet array. We also digitized 10,000 observations of historical shaking recorded over the past 400 years, and examined 300,000 earthquakes registered by the dense NIED/JMA network in a 3D geographic information system. In a principal departure from previous work, we propose that a 100-km-wide, 25-km-thick dislodged fragment of the Pacific plate is jammed between the Pacific, Philippine Sea and Eurasian plates beneath Tokyo, and argue that the this fragment controls much of Tokyo's seismic behavior, including the damaging 1855 M~7.1 Ansei-Edo shock. On the basis of the frequency of earthquakes beneath greater Tokyo, we estimate that events with magnitude and location similar to the Ansei-Edo event have a 20% likelihood in an average 30-yr period. In contrast, our renewal (time-dependent) probability for great M~7.9 megathrust shocks such as struck in 1923 and 1703 is just 0.5% for the next 30 years, with a time-averaged 30-yr probability of ~10%. The resulting net likelihood for severe shaking (~0.9 g peak ground acceleration) in Tokyo, Kawasaki, and Yokohama for the next 30 years is ~30%, and the annual probability is 1.3%.

  8. Thinking About the Unthinkable: Tokyo’s Nuclear Option

    Science.gov (United States)

    2009-01-01

    coalitions formed on a variety of issues—often under pressure.23 Proponents of Japanese nuclear- ization will inevitably encounter deep-seated resistance...overnight, especially if Tokyo initi- ated open, constructive consultations ahead of time. Even so, the transpacific al- liance would never be the same...strategies and developing a transpacific deter- rent, much as the U.S.-British alliance formulated a transatlantic deterrent to Soviet aggression

  9. Social capital and suicide: an ecological study in Tokyo, Japan.

    Science.gov (United States)

    Okamoto, Masumi; Kawakami, Norito; Kido, Yoshifumi; Sakurai, Keiko

    2013-07-01

    The aim of this study is to clarify the association between area-based social capital and suicide rate among municipalities of Tokyo. The study areas were 20 administrative municipalities of Tokyo. Social capital (i.e., organizational membership, social trust, fairness, helpfulness, and confidence in organizations) was measured based on data from a previous survey (response rate 28 %). Gender-specific age-adjusted suicide rates averaged over 5 years, sociodemographic, and other area characteristics were obtained from relevant national statistics. Multiple linear regression analysis of suicide rates was applied on each social capital variable, adjusting for the other area characteristics. There was no significant crude Pearson's correlation between any social capital variable and suicide rate. Multiple regression analyses revealed a significant negative association between social trust and suicide rate for men (p = 0.04). While based on only limited evidence from a cross-sectional ecological study, area-based social trust may be associated with decreased suicide rates for men in Tokyo.

  10. Airborne pollen and suicide mortality in Tokyo, 2001-2011.

    Science.gov (United States)

    Stickley, Andrew; Sheng Ng, Chris Fook; Konishi, Shoko; Koyanagi, Ai; Watanabe, Chiho

    2017-05-01

    Prior research has indicated that pollen might be linked to suicide mortality although the few studies that have been undertaken to date have produced conflicting findings and been limited to Western settings. This study examined the association between the level of airborne pollen and suicide mortality in Tokyo, Japan in the period from 2001 to 2011. The daily number of suicide deaths was obtained from the Japanese Ministry of Health, Labour and Welfare, with pollen data being obtained from the Tokyo Metropolitan Institute of Public Health. A time-stratified case-crossover study was performed to examine the association between different levels of pollen concentration and suicide mortality. During the study period there were 5185 male and 2332 female suicides in the pollen season (February to April). For men there was no association between airborne pollen and suicide mortality. For women, compared to when there was no airborne pollen, the same-day (lag 0) pollen level of 30 to Tokyo. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Development of a Screening Scale for High-Functioning Pervasive Developmental Disorders Using the Tokyo Child Development Schedule and Tokyo Autistic Behavior Scale

    Science.gov (United States)

    Suzuki, Mayo; Tachimori, Hisateru; Saito, Mari; Koyama, Tomonori; Kurita, Hiroshi

    2011-01-01

    This study aimed to compile a screening scale for high-functioning pervasive developmental disorders (PDD), using the Tokyo Child Development Schedule (TCDS) and Tokyo Autistic Behavior Scale (TABS). The 72 participants (IQ greater than or equal to 70) were divided into 3 groups after IQ matching depending on their diagnoses: i.e., PDD,…

  12. Afasia motora congénita (informe preliminar presentado al Primer Congreso Colombiano de Neurología

    Directory of Open Access Journals (Sweden)

    Juan Antonio Gómez

    1966-01-01

    Full Text Available El estudio del lenguaje, antes de que exista, es un campo bastante confuso de la neurología. No sólo participa de la caótica interpretación que diferentes escuelas actuales dan al fenómeno clínico de afasia sino que linda con el problema mismo de la evolución y creación del lenguaje, base de la cultura. De nuestro material clínico hemos escogido un grupo de 23 niños con afasia de la llamada "congénita", entre los cuales había 11 casos de afasia motora. Nueve se estudiaron bajo el punto de vista neurológico, psicológico, psicométrico, pedagógico y social. Todos fueron examinados radiológicamente, audiométricamente y electroencefalográficamente. El objeto del presente trabajo es presentar las manifestaciones neurológicas de los niños con afasia motora congénita principalmente, y discutir algunos puntos del diagnóstico diferencial y del posible mecanismo neurológico que ha impedido el desarrollo del lenguaje.

  13. Tokyo Metropolitan Earthquake Preparedness Project - A Progress Report

    Science.gov (United States)

    Hayashi, H.

    2010-12-01

    Munich Re once ranked that Tokyo metropolitan region, the capital of Japan, is the most vulnerable area for earthquake disasters, followed by San Francisco Bay Area, US and Osaka, Japan. Seismologists also predict that Tokyo metropolitan region may have at least one near-field earthquake with a probability of 70% for the next 30 years. Given this prediction, Japanese Government took it seriously to conduct damage estimations and revealed that, as the worst case scenario, if a7.3 magnitude earthquake under heavy winds as shown in the fig. 1, it would kill a total of 11,000 people and a total of direct and indirect losses would amount to 112,000,000,000,000 yen(1,300,000,000,000, 1=85yen) . In addition to mortality and financial losses, a total of 25 million people would be severely impacted by this earthquake in four prefectures. If this earthquake occurs, 300,000 elevators will be stopped suddenly, and 12,500 persons would be confined in them for a long time. Seven million people will come to use over 20,000 public shelters spread over the impacted area. Over one millions temporary housing units should be built to accommodate 4.6 million people who lost their dwellings. 2.5 million people will relocate to outside of the damaged area. In short, an unprecedented scale of earthquake disaster is expected and we must prepare for it. Even though disaster mitigation is undoubtedly the best solution, it is more realistic that the expected earthquake would hit before we complete this business. In other words, we must take into account another solution to make the people and the assets in this region more resilient for the Tokyo metropolitan earthquake. This is the question we have been tackling with for the last four years. To increase societal resilience for Tokyo metropolitan earthquake, we adopted a holistic approach to integrate both emergency response and long-term recovery. There are three goals for long-term recovery, which consists of Physical recovery, Economic

  14. Clorhidrorrea congénita:: primer reporte en Cuba Congenital chlorhydria:: first report in Cuba

    Directory of Open Access Journals (Sweden)

    Carlos Ramírez Pérez

    2009-12-01

    Full Text Available En el presente trabajo se exponen los antecedentes prenatales, perinatales y posnatales de un lactante de 6 meses de edad, del sexo masculino, con clorhidrorrea congénita, así como el cuadro clínico, diagnóstico y tratamiento utilizado. Un elemento significativo lo constituyó la expulsión anal de abundante líquido no meconial desde las primeras horas de nacido, así como alcalosis metabólica grave y la presencia de desnutrición rápidamente progresiva. En los exámenes complementarios se constató hipocloremia de un 50 % con respecto a las cifras de referencia y un pH sanguíneo mayor de 7,50. El diagnóstico confirmatorio se obtuvo al comprobar concentraciones de cloro en heces fecales superiores a las de la suma de sodio y potasio. Se proponen indicadores diagnósticos prenatales entre los que tienen gran valor la consanguinidad, el polihidramnios y los resultados del ultrasonido en el tercer trimestre del embarazo. El diagnóstico precoz permitió establecer el tratamiento y evitó el frecuente desenlace fatal. Es el primer caso de esta enfermedad que se informa en el país.In present paper are showed the prenatal, perinatal and postnatal backgrounds from a male breast-fed baby aged 6 months presenting with congenital chlorhydria, as well as the clinical picture, diagnosis and treatment applied. A significant element was the anal expulsion of non-meconium abundant fluid from the first hours of born, as well as a severe metabolic alkalosis and the presence of a quickly progressive malnutrition. In complementary examinations was confirmed a 50% hypochloremia regarding the reference figures and a blood pH over 7,50. Confirmatory diagnosis was achieved verifying the chlorine concentrations in feces higher to that of the sum of sodium and potassium. Prenatal diagnostic indicators are proposed those with higher value including the consanguinity, polyhydramnios and the US results during the third trimester of pregnancy. Early diagnosis

  15. A new tomographic image on the Philippine Sea Slab beneath Tokyo - Implication to seismic hazard in the Tokyo metropolitan region -

    Science.gov (United States)

    Hirata, N.; Sakai, S.; Nakagawa, S.; Ishikawa, M.; Sato, H.; Kasahara, K.; Kimura, H.; Honda, R.

    2012-12-01

    In central Japan, the Philippine Sea plate (PSP) subducts beneath the Tokyo metropolitan region. Devastating M8-class earthquakes occurred on the upper surface of the Philippine Sea plate (SPS), examples of which are the Genroku earthquake of 1703 (magnitude M=8.0) and the Kanto earthquake of 1923 (M=7.9), which had 105,000 fatalities. A M7 or greater (M7+) earthquake in this region at present has high potential to produce devastating loss of life and property with even greater global economic repercussions although it is smaller than the megathrust type M8-class earthquakes. This great earthquake is evaluated to occur with a probability of 70 % in 30 years by the Earthquake Research Committee of Japan. The M7+ earthquakes may occur either on the upper surface or intra slab of PSP. The Central Disaster Management Council of Japan estimates the next great M7+ earthquake will cause 11,000 fatalities and 112 trillion yen (1 trillion US$) economic loss at worst case if it occur beneath northern Tokyo bay with M7.3. However, the estimate is based on a source fault model by conventional studies about the PSP geometry. To evaluate seismic hazard due to the great quake we need to clarify the geometry of PSP and also the Pacific palate (PAP) that subducs beneath PSP. We identify those plates with use of seismic tomography and available deep seismic reflection profiling and borehole data in southern Kanto area. We deployed about 300 seismic stations in the greater Tokyo urban region under the Special Project for Earthquake Disaster Mitigation in Tokyo Metropolitan Area. We obtain clear P- and S- wave velocity (Vp and Vs) tomograms which show a clear image of PSP and PAP. A depth to the top of PSP, 20 to 30 kilometer beneath northern part of Tokyo bay, is about 10 km shallower than previous estimates based on the distribution of seismicity (Ishida, 1992). This shallower plate geometry changes estimations of strong ground motion for seismic hazards analysis within the Tokyo

  16. Health risks and precautions for visitors to the Tokyo 2020 Olympic and Paralympic Games.

    Science.gov (United States)

    Nakamura, Sachiko; Wada, Koji; Yanagisawa, Naoki; Smith, Derek R

    2018-02-02

    In 2020, Japan will host the Tokyo Olympic and Paralympic Games in 2020 (Tokyo 2020) which will involve a large population influx from various countries to Tokyo, the most populated city in Japan. We summarize the potential health risks for visitors to Tokyo 2020, related to communicable disease risks and other health threats, based on recent national and local surveillance reports. We reviewed up-to-date surveillance reports published by the National Institute of Infectious Diseases and Tokyo Metropolitan Infectious Disease Surveillance Center. Communicable disease risks for vaccine-preventable illnesses such as measles and rubella, as well as food and waterborne diseases represent the most likely risks. The risk of acquiring vector-borne diseases is considered low in Japan. On the other hand, however, heat-related illness represents a potential risk, as Tokyo 2020 is scheduled during the hottest season in Japan, with temperatures generally expected to exceed 30 °C. Maintaining an up-to-date routine vaccination schedule is highly recommended for visitors attending the Tokyo 2020 and appropriate hygiene measures for food and waterborne diseases as well as health promotion for heat-related illness. It may also be useful to increase the number of multilingual triage clinicians whom can be placed within emergency departments during the Tokyo 2020 to provide first contact services and coordination of emergency care among non-Japanese speaking visitors to Tokyo. Copyright © 2018. Published by Elsevier Ltd.

  17. Anestesia no cardiovascular en el adulto con cardiopatía congénita cianótica

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2004-03-01

    Full Text Available Como resultado del progreso en el diagnóstico y tratamiento de las cardiopatías congénitas, la esperanza de vida aumenta considerablemente en nuestro medio. Consecuentemente más niños crecen hasta convertirse en adultos y un grupo de ellos serán sometidos a procedimientos quirúrgicos no cardiovasculares. Estos pacientes constituyen un reto para los anestesiólogos por 3 motivos: 1. Existe una gran variedad de variedades anatómicas y fisiológicas; 2. La capacidad cardiovascular y pulmonar están afectadas de forma significativa y 3. Existe poca información disponible acerca del manejo anestésico de estos pacientes. Las operaciones no cardiovasculares en los pacientes que padecen o han sido operados por padecer cardiopatías congénitas, deben realizarse si es posible, en hospitales de primer nivel y el anestesiólogo responsable debe tener experiencia previa en anestesia cardiovascular pediátrica o por lo menos acceso directo a consulta con un anestesiólogo cardiovascular pediátrico. Se presenta una revisión bibliográfica actualizada sobre el manejo anestésico de los pacientes que padecen de cardiopatías congénitas cianóticas sometidos a procedimientos quirúrgicos no cardiovascularesAs a result of the progress attained in the diagnosis and treatment of congenital heart diseases, life expectancy increases considerably in our environment. Consequently, more children grow up until becoming adults and some of them will undergo noncardiovascular surgical procedures. These patients are a challenge for anesthesiologists for 3 reasons: 1. There is a great number of anatomical and physiological varieties; 2. The cardiovascular and pulmonary capacities are significantly affected; 3. There is little information available about the anesthetic management of these patients. The noncardiovascular operations in patients suffering from heart diseases or that have undergone surgery due to congenital heart diseases, should be performed if

  18. Ambient air pollution and suicide in Tokyo, 2001-2011.

    Science.gov (United States)

    Ng, Chris Fook Sheng; Stickley, Andrew; Konishi, Shoko; Watanabe, Chiho

    2016-09-01

    Some evidence suggests an association may exist between the level of air pollution and suicide mortality. However, this relation has been little studied to date. The current study examined the association in Tokyo, Japan. Suicide mortality data for Tokyo for the 11-year period 2001-2011 were obtained together with data on four air pollutants: fine particulate matter (PM2.5), suspended particulate matter (SPM), sulphur dioxide (SO2) and nitrogen dioxide (NO2). A time-stratified case-crossover study design was used to examine the daily association between the level of air pollution and suicide mortality. During the study period there were 29,939 suicide deaths. In stratified analyses an interquartile range (IQR) increase in the same-day concentration of NO2 was linked to increased suicide mortality among those aged under 30 (percentage change: 6.73%, 95% CI: 0.69-13.12%). An IQR increase in PM2.5 and SO2 was associated with a 10.55% (95% CI: 2.05-19.75%) and 11.47% (95% CI: 3.60-19.93%) increase, respectively, in suicide mortality among widowed individuals for mean exposure on the first four days (average lags 0-3). Positive associations were observed for the air pollutants in the summer although associations were reversed in autumn. We relied on monitoring data to approximate individual exposure to air pollutants. Higher levels of air pollution are associated with increased suicide mortality in some population subgroups in Tokyo. Further research is needed to elucidate the mechanisms linking air pollutants and suicide in this setting. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Urban expansion in Tokyo metropolitan area between 1972 and 2002

    Science.gov (United States)

    Bagan, H.; Yamagata, Y.

    2010-12-01

    According to World Bank Report, more than half of the world’s population is now living in cities and over two-thirds of greenhouse gas emissions come from cities worldwide. The Kanto Plain is the largest plain in Japan, which experienced the greatest urban expansion in the 20th century. Satellite images collected over a span of years can be used to identify and characterize both natural and anthropogenic changes over large areas of land. Landsat satellite images are ideal for this purpose; imagery recorded over nearly four decades provides a unique resource for temporal analysis of urban area land cover change. The purpose of this study was to investigate spatial and temporal urban area changes in the Tokyo Metropolitan Area (include the neighboring regions). and to investigate the possible causes of those changes. To do this, we applied land-cover classification schemes to Multispectral Scanner (MSS), Thematic Mapper (TM), and Enhanced Thematic Mapper Plus (ETM+) sensor images recorded between 1972 and 2002, which we acquired from the Landsat archive. We used two supervised classification methods, the self-organizing map (SOM) neural network method and the subspace method, to accurately classify land cover on Landsat images recorded in 1972, 1985, and 2002. This allowed us to quantitatively present urban area changes between 1972 and 2002, and allowed us to analyze its relation with multi-time 1 kilometer grid population density census data to further report on the trends of urban expansion. Figure 1 shows the urban area in 1972, and figure 2 shows the urban area in 2002. From the two maps, along with the high economic growth of the Japanese economy, the concentration of the population in Tokyo extremely increased over the period from 1972 to 2002. As a result, these factors lead to urban sprawl in the suburban areas of Tokyo Metropolitan Area. Figure 1. Urban area in 1972. Figure 2. Urban area in 2002.

  20. ¿Es necesario disponer de ECMO para reparar cardiopatías congénitas de complejidad elevada? Nuestra experiencia en los últimos 6 años

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    Raúl Sánchez Pérez

    2017-01-01

    Conclusiones: Creemos que actualmente es necesario disponer de la ECMO en el postoperatorio de los pacientes intervenidos de cardiopatías congénitas, dado que parece asociarse a un beneficio en términos de supervivencia.

  1. The environmental response of Middle Ordovician large organic walled microfossils from the Goldwyer and Nita Formations, Canning Basin, Western Australia.

    Science.gov (United States)

    Winchester-Seeto, T; Foster, C; O'Leary, T

    2000-12-01

    Middle Ordovician large organic walled microfossils (chitinozoans, scolecodonts, hydrozoans and foraminiferal linings) were recovered from the upper Goldwyer and lower Nita formations, Canning Basin, Western Australia, from three cores (WMC Santalum 1A, Kunzea 1 and Acacia 2). Petrophysical logs of these cores reveal an overall upward shallowing supersequence, overprinted by numerous transgression/regression couplets that can be correlated over 100km.Analysis of the abundance of the microfossils with respect to the gamma log signatures reveals that both chitinozoan abundance and diversity decrease as water depth shallows; however, the opposite is not always true and other factors probably intervene. Scolecodonts show an increase in abundance in transgressions, while hydrozoans and foraminiferal linings show no consistent response to trangressive or regressive phases. Cyathochitina hunderumensis tends to dominate chitinozoan assemblages where there is a transgression, while species of Belonechitina replace Cy. hunderumensis in regressive phases.

  2. Tratamiento simultáneo de anquilosis temporomandibular unilateral congénita y del microlaterognatismo asociado

    Directory of Open Access Journals (Sweden)

    José Felipe Basulto Varela

    2013-03-01

    Full Text Available Este artículo tiene como objetivo reportar los resultados obtenidos a corto y largo plazo, del tratamiento con enfoque multidisciplinario de una anquilosis unilateral congénita de la articulación temporomandibular asociada a un síndrome de malformación embrionaria, en un niño de 12 años de edad, en el que se utilizó un distractor externo bidimensional con un doble propósito: como fijador para mantener el espacio logrado con la artroplastia y como distractor para elongar la rama mandibular hipotrófica, activado 5 días después de la osteotomía, con el objetivo de eliminar la anquilosis y el microlaterognatismo mandíbular consecutivo de ella, simultaneamente de manera funcional y dinámica.

  3. Contractura congénita en abducción de la cadera y oblicuidad pélvica

    OpenAIRE

    Seral García, Belén; Bello Nicolau, M. L.; Seral Iñigo, Fernando

    1999-01-01

    La contractura congénita en abducción y oblicuidad apévica una patología que estamos viendo con cierta frecuencia en nuestra consulta de Ortopedia infantil, y a pesar de ser poco conocida por lo poco descrito en la literatura, nos parece un tema importante. Aportamos 4 casos tratados y seguidos en nuestra consulta. Describimos la exploración clínica y radiológica de estos pacientes, así como su evolución en el tiempo y pronóstico. Planteamos el diagnóstico diferencial con la luxación congénit...

  4. Malformación Congénita del fémur. Uso de Ortoprótesis.

    Directory of Open Access Journals (Sweden)

    Yeney Díaz Díaz

    2015-09-01

    Full Text Available En todo tiempo el tratamiento técnico ortopédico de los defectos congénitos y pérdidas de sustancia ósea adquirida de las extremidades han formado parte de la tarea de los cirujanos ortopédicos. Objetivo: presentar un aditamento ortopédico elaborado en el Laboratorio de Ortoprotésis de la provincia de Sancti Spíritus con el fin de corregir un caso con malformación congénita de fémur. Se presenta el caso de un escolar de 8 años de edad segundo hijo nacido de un parto eutócico en el nacimiento se observa la malformación congénita de fémur, se recoge como antecedente familiar importante un familiar alejado del abuelo materno con la misma patología. El paciente es valorado en consulta en el 2012 después de realizar el interrogatorio, examen físico y la elaboración de la historia clínica se hace un análisis del mismo en conjunto con el licenciado en Ortoprótesis y se decide realizar en un inicio una Ortesis larga con asentamiento isquiático y cinturón pélvico y se propone el uso de la Ortoprótesis para mejorar el bienestar del niño, además evitar otras complicaciones. Se concluye que con el uso de la Ortoprótesis se logra un desarrollo psicomotor normal en estos pacientes.

  5. Frecuencia de anomalías congénitas en el Instituto Materno Infantil de Bogotá.

    Directory of Open Access Journals (Sweden)

    Herbert García

    2003-06-01

    Full Text Available Se analizaron 5.686 nacimientos (5.597 vivos y 89 muertos correspondientes a dos series realizadas entre los meses de octubre de 1997 y abril de 1998 y de julio a noviembre de 2000 (12 meses en el Instituto Materno Infantil de Bogotá. Se detectaron anomalías congénitas en 4,4% de los recién nacidos vivos y en 7,8% de los mortinatos. Las anomalías mayores constituyen el 69% de todas las anomalías y se encuentran en 3% de los recién nacidos vivos. Las anomalías moderadas son el 31% de todas las anomalías y se detectaron en 1,4% de los recién nacidos vivos. Los recién nacidos con anomalías mayores, en comparación con los controles, registran una mayor mortalidad al momento del alta hospitalaria (p=0,0001, menor peso promedio al nacer (p=0,003 y antecedentes de anomalía en la familia (p=0,0001. Las anomalías moderadas están asociadas únicamente con antecedentes de anomalías familiares (p=0,0001. Las anomalías congénitas muestran una frecuencia en nuestro medio semejante a las de otros estudios del país y del exterior, aunque, individualmente, algunas anomalías muestran variaciones significativas en sus frecuencias que pueden deberse a sobre o subregistros o a diferencias metodológicas en su detección.

  6. Malformaciones congénitas renales en el paciente pediátrico de la provincia de Mayabeque

    Directory of Open Access Journals (Sweden)

    Mercedes Silva Rojas

    2014-08-01

    Full Text Available Las anomalías congénitas del riñón y del tracto urinario representan un porciento importante de todas las anomalías identificadas en el periodo neonatal, dando lugar a una amplia variedad de desórdenes; por este motivo se implementó la presente investigación, con el objetivo de describir el comportamiento de las malformaciones congénitas renales en la edad pediátrica, ocurridas en la provincia de Mayabeque durante el segundo semestre del año 2013. Se realizó un estudio descriptivo prospectivo de corte transversal, con el universo de los niños atendidos en la consulta de nefrología pediátrica provincial del Hospital General Docente “Aleida Fernández Chardiet”, del municipio de Güines, en la referida provincia. La muestra quedó conformada por los 18 niños con malformaciones renales, que fueron atendidos de julio a diciembre de 2013. En el 50% de ellos se les realizó el diagnosticó durante el primer año de vida y predominó en el sexo masculino (66,6%. El 50% asistió a consulta por infección del tracto urinario y todos los pacientes presentaron alteraciones en el ultrasonido y la gammagrafía. Estos resultados permiten conocer el comportamiento de las malformaciones renales y tomar una conducta adecuada para mejorar la calidad de vida en estos pacientes

  7. 213. Resultados de la cirugía en pacientes con cardiopatía congénita en la edad adulta durante los últimos 5 años

    Directory of Open Access Journals (Sweden)

    D. Cabestrero Alonso

    2012-04-01

    Conclusiones: Los pacientes adultos intervenidos portadores de cardiopatías congénitas complejas aumentan progresivamente. La mayoría han sido sometidos a múltiples intervenciones y su cirugía presenta una alta complejidad, por lo que consideramos que son sugestivos de un tratamiento por equipos con amplia experiencia en cardiopatías congénitas.

  8. The Thirteenth International Conference on Endothelin (ET-13), Tokyo, 2013.

    Science.gov (United States)

    Emoto, Noriaki; Yanagisawa, Masashi

    2014-11-24

    The Thirteenth International Conference on Endothelin (ET-13) was held from September 8-11, 2013 in Tokyo, Japan chaired by Noriaki Emoto, Kobe Pharmaceutical University, Japan, and Takashi Miyauchi, University of Tsukuba, Japan and held on the Tokyo Campus of Tsukuba University. The International Conferences on Endothelin were launched in December of 1988 shortly after the discovery of endothelin and organized by Sir John Vane, laureate of the Nobel Prize in Physiology or Medicine 1982, as the Conference Chair at The William Harvey Research Institute, London. Since then, the conference has been held every two years alternating between North America, Europe and Asia. In 2013, the conference was again held in Asia and also marked the 25th anniversary of the discovery of endothelin at University of Tsukuba. The 25th anniversary of the discovery of endothelin was celebrated by almost 300 attendees from 25 different countries, the largest number of delegates in the recent history of the conference. Conference delegates who traveled to Japan were from Argentina, Australia, Austria, Brazil, Canada, China, Czech Republic, Denmark, France, Germany, Greece, Hong Kong, Hungary, Indonesia, Italy, Japan, Korean Republic, Netherlands, Sweden, Switzerland, Taiwan, Turkey, United Kingdom, United States, and from Vietnam. In this article we summarize the conference highlights, its speakers, and some of the festivities related to the celebration of the 25th anniversary of the discovery of endothelin. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Characteristics of Individuals With Mental Illness in Tokyo Homeless Shelters.

    Science.gov (United States)

    Okamura, Tsuyoshi; Takeshima, Tadashi; Tachimori, Hisateru; Takiwaki, Ken; Matoba, Yuki; Awata, Shuichi

    2015-12-01

    Japan has the largest number of psychiatric beds in the world and has been in the process of deinstitutionalization since 2004. The majority of psychiatric inpatients are elderly long-term patients, who are at risk of homelessness after they are discharged. There is little information about homeless people with mental illnesses in Japan, and the aim of this study was to describe characteristics of people with a mental illness in homeless shelters in Tokyo. A face-to-face survey was conducted from December 2012 to March 2013 by the staff of a nonprofit organization (NPO) that helps socially isolated persons. Of the 1,056 people who received help during the study period, 684 completed the survey. Eighteen percent of the 684 survey participants had a mental illness. Of the 210 individuals who lived in shelters, one-third had a mental illness. The mean age of shelter users with mental illness was 64.9; they tended to be referred from hospitals, and their mental well-being was poorer than other NPO service users in the study. Among the service users with mental illness, those living in shelters were older than those living in the community and more likely to have a history of trouble with alcohol, poor family relationships, and impaired instrumental activities of daily living. Unmet mental health needs were noted among discharged hospital patients living in Tokyo homeless shelters. An integrated and community-based support system with more effective health care delivery, including critical time interventions, is needed.

  10. The Tokyo subway sarin attack--lessons learned.

    Science.gov (United States)

    Okumura, T; Hisaoka, T; Yamada, A; Naito, T; Isonuma, H; Okumura, S; Miura, K; Sakurada, M; Maekawa, H; Ishimatsu, S; Takasu, N; Suzuki, K

    2005-09-01

    The sarin gas attack in the Tokyo subway system is reviewed from a clinical toxicology perspective. Based on the lessons learned from this attack, the following areas should be addressed on a global scale. First, an adequate supply of protective equipment is required, including level B protective equipment with a pressure demand breathing apparatus. In addition, a system should be established that enables a possible cause to be determined based on symptoms, physical findings, general laboratory tests, and a simple qualitative analysis for poisonous substances. If an antidote is needed, the system should enable it to be administered to the victims as quickly as possible. Preparation for a large-scale chemical attack by terrorists requires the prior establishment of a detailed decontamination plan that utilizes not only mass decontamination facilities but also public facilities in the area. A system should be established for summarizing, evaluating, and disseminating information on poisonous substances. Finally, a large-scale scientific investigation of the Tokyo sarin attack should be conducted to examine its long-term and subclinical effects and the effects of exposure to asymptomatic low levels of sarin.

  11. Station area developments in Tokyo and what the Randstad can learn from it

    NARCIS (Netherlands)

    Chorus, P.R.W.E.

    2012-01-01

    Tokyo is a clear example of a railway-oriented city. During a period of strong economic growth after World War II it was largely the railways that facilitated the development direction of Tokyo. As a result vast stretches of land around the railway lines radiating outwards from the city centre have

  12. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos)

    NARCIS (Netherlands)

    Yokoe, Masamichi; Hata, Jiro; Takada, Tadahiro; Strasberg, Steven M.; Asbun, Horacio J.; Wakabayashi, Go; Kozaka, Kazuto; Endo, Itaru; Deziel, Daniel J.; Miura, Fumihiko; Okamoto, Kohji; Hwang, Tsann-Long; Huang, Wayne Shih-Wei; Ker, Chen-Guo; Chen, Miin-Fu; Han, Ho-Seong; Yoon, Yoo-Seok; Choi, In-Seok; Yoon, Dong-Sup; Noguchi, Yoshinori; Shikata, Satoru; Ukai, Tomohiko; Higuchi, Ryota; Gabata, Toshifumi; Mori, Yasuhisa; Iwashita, Yukio; Hibi, Taizo; Jagannath, Palepu; Jonas, Eduard; Liau, Kui-Hin; Dervenis, Christos; Gouma, Dirk J.; Cherqui, Daniel; Belli, Giulio; Garden, O. James; Giménez, Mariano Eduardo; de Santibañes, Eduardo; Suzuki, Kenji; Umezawa, Akiko; Supe, Avinash Nivritti; Pitt, Henry A.; Singh, Harjit; Chan, Angus C. W.; Lau, Wan Yee; Teoh, Anthony Yuen Bun; Honda, Goro; Sugioka, Atsushi; Asai, Koji; Gomi, Harumi; Itoi, Takao; Kiriyama, Seiki; Yoshida, Masahiro; Mayumi, Toshihiko; Matsumura, Naoki; Tokumura, Hiromi; Kitano, Seigo; Hirata, Koichi; Inui, Kazuo; Sumiyama, Yoshinobu; Yamamoto, Masakazu

    2018-01-01

    The Tokyo Guidelines 2013 (TG13) for acute cholangitis and cholecystitis were globally disseminated and various clinical studies about the management of acute cholecystitis were reported by many researchers and clinicians from all over the world. The 1st edition of the Tokyo Guidelines 2007 (TG07)

  13. Education for Earthquake Disaster Prevention in the Tokyo Metropolitan Area

    Science.gov (United States)

    Oki, S.; Tsuji, H.; Koketsu, K.; Yazaki, Y.

    2008-12-01

    Japan frequently suffers from all types of disasters such as earthquakes, typhoons, floods, volcanic eruptions, and landslides. In the first half of this year, we already had three big earthquakes and heavy rainfall, which killed more than 30 people. This is not just for Japan but Asia is the most disaster-afflicted region in the world, accounting for about 90% of all those affected by disasters, and more than 50% of the total fatalities and economic losses. One of the most essential ways to reduce the damage of natural disasters is to educate the general public to let them understand what is going on during those desasters. This leads individual to make the sound decision on what to do to prevent or reduce the damage. The Ministry of Education, Culture, Sports, Science and Technology (MEXT), therefore, offered for public subscription to choose several model areas to adopt scientific education to the local elementary schools, and ERI, the Earthquake Research Institute, is qualified to develop education for earthquake disaster prevention in the Tokyo metropolitan area. The tectonic setting of this area is very complicated; there are the Pacific and Philippine Sea plates subducting beneath the North America and the Eurasia plates. The subduction of the Philippine Sea plate causes mega-thrust earthquakes such as the 1703 Genroku earthquake (M 8.0) and the 1923 Kanto earthquake (M 7.9) which had 105,000 fatalities. A magnitude 7 or greater earthquake beneath this area is recently evaluated to occur with a probability of 70 % in 30 years. This is of immediate concern for the devastating loss of life and property because the Tokyo urban region now has a population of 42 million and is the center of approximately 40 % of the nation's activities, which may cause great global economic repercussion. To better understand earthquakes in this region, "Special Project for Earthquake Disaster Mitigation in Tokyo Metropolitan Area" has been conducted mainly by ERI. It is a 4-year

  14. Deficiência Congénita Femural e Hemimélia Fibular – Amputação e Protetização

    OpenAIRE

    Costa, MJ

    2011-01-01

    As malformações congénitas dos membros inferiores têm uma grande variedade de apresentação clínica associada a grande leque de dismetria dos membros. As classificações de Paley para a hemimélia fibular e para a deficiência femural congénita, dão orientação para o tratamento destes doentes: cirurgia de alongamento versus cirurgia de amputação. Em qualquer das situações, as crianças têm de ser protetizadas para poderem fazer marcha, correr e brincar. A protetização de uma c...

  15. Concentration and temperature dependence of short-range order in Ni-Ta solid solution using X-ray diffraction method

    International Nuclear Information System (INIS)

    Khwaja, F.A.; Alam, A.

    1980-09-01

    Diffuse X-ray scattering investigations about the existence of short-range order (SRO) have been carried out in the Ni-Ta system for different concentrations and annealing temperatures. It is observed that the values of the SRO parameters for the first co-ordination shell have anomalously large negative values for all the samples studied. These values of the α 1 depend upon the annealing temperatures and the concentration of Ta atoms in the Ni-Ta system. The results of the theoretical predictions of the ordering potential obtained using the formulae of the electronic theory of SRO, confirm the existence of very strong attractive correlation between the atoms of the different species in this system. (author)

  16. 75 FR 11919 - Qimonda 200 MM Facility, Including On-Site Leased Workers From Tokyo Electron America, Nikon...

    Science.gov (United States)

    2010-03-12

    ... Employment and Training Administration Qimonda 200 MM Facility, Including On-Site Leased Workers From Tokyo... 17, 2009 and December 31, 2009 to include on-site leased workers of Tokyo Electron America, Nikon... as follows: All workers of Qimonda 200MM Facility, including on-site leased workers from Tokyo...

  17. RUBÉOLA CONGÉNITA, COMUNICACIÓN DE UN CASO Y SU EVOLUCIÓN VEINTITRÉS AÑOS DESPUÉS

    Directory of Open Access Journals (Sweden)

    Alvaro Rodríguez

    2012-01-01

    Full Text Available Se reporta un caso de Rubéola Congénita, sordera, cataratas operadas tempranamente y maculopatía en ambos ojos. Se describen las características clínicas, sus implicaciones evalua-das con técnicas diagnósticas actualizadas en su evolución de 23 años. También el manejo del caso y su rehabilitación.

  18. RUBÉOLA CONGÉNITA, COMUNICACIÓN DE UN CASO Y SU EVOLUCIÓN VEINTITRÉS AÑOS DESPUÉS

    OpenAIRE

    Alvaro Rodríguez; Felipe Escallón; Marcela Valencia; Claudia Castaño

    2012-01-01

    Se reporta un caso de Rubéola Congénita, sordera, cataratas operadas tempranamente y maculopatía en ambos ojos. Se describen las características clínicas, sus implicaciones evalua-das con técnicas diagnósticas actualizadas en su evolución de 23 años. También el manejo del caso y su rehabilitación.

  19. Towards more stable operation of the Tokyo Tier2 center

    Science.gov (United States)

    Nakamura, T.; Mashimo, T.; Matsui, N.; Sakamoto, H.; Ueda, I.

    2014-06-01

    The Tokyo Tier2 center, which is located at the International Center for Elementary Particle Physics (ICEPP) in the University of Tokyo, was established as a regional analysis center in Japan for the ATLAS experiment. The official operation with WLCG was started in 2007 after the several years development since 2002. In December 2012, we have replaced almost all hardware as the third system upgrade to deal with analysis for further growing data of the ATLAS experiment. The number of CPU cores are increased by factor of two (9984 cores in total), and the performance of individual CPU core is improved by 20% according to the HEPSPEC06 benchmark test at 32bit compile mode. The score is estimated as 18.03 (SL6) per core by using Intel Xeon E5-2680 2.70 GHz. Since all worker nodes are made by 16 CPU cores configuration, we deployed 624 blade servers in total. They are connected to 6.7 PB of disk storage system with non-blocking 10 Gbps internal network backbone by using two center network switches (NetIron MLXe-32). The disk storage is made by 102 of RAID6 disk arrays (Infortrend DS S24F-G2840-4C16DO0) and served by equivalent number of 1U file servers with 8G-FC connection to maximize the file transfer throughput per storage capacity. As of February 2013, 2560 CPU cores and 2.00 PB of disk storage have already been deployed for WLCG. Currently, the remaining non-grid resources for both CPUs and disk storage are used as dedicated resources for the data analysis by the ATLAS Japan collaborators. Since all hardware in the non-grid resources are made by same architecture with Tier2 resource, they will be able to be migrated as the Tier2 extra resource on demand of the ATLAS experiment in the future. In addition to the upgrade of computing resources, we expect the improvement of connectivity on the wide area network. Thanks to the Japanese NREN (NII), another 10 Gbps trans-Pacific line from Japan to Washington will be available additionally with existing two 10 Gbps lines

  20. [Current and future legislation of illegal drugs in Tokyo].

    Science.gov (United States)

    Abe, Tetsuya

    2013-01-01

    Abuse of illegal drugs is widespread among young people, especially in the so-called "dance club scene" or "rave scene". Severe and even fatal poisonings have been attributed to the consumption of such drugs of abuse. The actions against these drugs by the Tokyo Metropolitan Government and subsequently by the Government of Japan have gone some way to reducing the potential harm caused by these substances. However, alternative products have been advertised on a number of websites. During our careful surveillance of illegal drugs in 2011, we found seven unregulated drugs advertised. This means that we have an obligation to continue strict surveillance of illegal drugs and to structure a system of temporary bans on illegal drugs.

  1. Assessment of earthquake hazard in the Tokyo area, Japan

    Science.gov (United States)

    Rikitake, T.

    1991-12-01

    The probability of occurrence of an inland earthquake originating beneath the Tokyo area is evaluated for a 10-year period from 1991. On the basis of an earthquake catalogue containing some 40 earthquakes, which caused some damage to Edo (now Tokyo) over a period of 400 years, the parameters of the Weibull and lognormal probability distributions applied to recurrence interval statistics are estimated. With these parameters, it is concluded that an earthquake directly beneath the capital, the magnitude of which is equal to or greater than 6.0, occurs with a probability of 0.40 for the period in question. When the magnitude threshold is assumed as 6.4 and 7.0, the probabilities become 0.17 and 0.049, respectively. These probability evaluations are extended to those for the seismic intensity at typical sites in the area, although no accurate evaluation is possible because the exact focal depths of historical earthquakes are not known. On the assumption that these earthquakes occur near the upper surface of the down-going Philippine Sea plate, however, a typical depth of 30 km or so is suggested. Should an earthquake having a mean magnitude of 6.4, say, and at a mean location of past earthquakes occur, the probability of seismic intensity at typical sites in the capital area exceeding 5 on the Japan Meteorological Agency (JMA) scale would amount to 0.17. The possibility of having a highly damaging earthquake of intensity 6 on the JMA scale also cannot be ruled out, judging from earthquake disasters in the past, although the probability does become lower. To summarize, it may be said that the probability of Japan's capital area being hit by a damaging earthquake in the foreseeable future is not particularly low.

  2. Preventing heat illness in the anticipated hot climate of the Tokyo 2020 Summer Olympic Games.

    Science.gov (United States)

    Kakamu, Takeyasu; Wada, Koji; Smith, Derek R; Endo, Shota; Fukushima, Tetsuhito

    2017-09-19

    Amid the effects of global warming, Tokyo has become an increasingly hot city, especially during the summertime. To prepare for the upcoming 2020 Summer Olympics and Paralympics in Tokyo, all participants, including the athletes, staff, and spectators, will need to familiarize themselves with Tokyo's hot and humid summer conditions. This paper uses the wet-bulb globe temperature (WBGT) index, which estimates the risk of heat illness, to compare climate conditions of sports events in Tokyo with the conditions of the past three Summer Olympics (held in Rio de Janeiro, London, and Beijing) and to subsequently detail the need for establishing appropriate countermeasures. We compared WBGT results from the past three Summer Olympics with the same time periods in Tokyo during 2016. There was almost no time zone where a low risk of heat illness could be expected during the time frame of the upcoming 2020 Tokyo Olympics. We also found that Tokyo had a higher WBGT than any of those previous host cities and is poorly suited for outdoor sporting events. Combined efforts by the official organizers, government, various related organizations, and the participants will be necessary to deal with these challenging conditions and to allow athletes to perform their best, as well as to prevent heat illnesses among staff and spectators. The sporting committees, as well as the Olympic organizing committee, should consider WBGT measurements in determining the venues and timing of the events to better avoid heat illness and facilitate maximum athletic performance.

  3. Impact on ambient dose rate in metropolitan Tokyo from the Fukushima Daiichi Nuclear Power Plant accident.

    Science.gov (United States)

    Inoue, Kazumasa; Tsuruoka, Hiroshi; Van Le, Tan; Arai, Moeko; Saito, Kyoko; Fukushi, Masahiro

    2016-07-01

    A car-borne survey was made in metropolitan Tokyo, Japan, in December 2014 to estimate external dose. This survey was conducted for all municipalities of Tokyo and the results were compared with measurements done in 2003. The ambient dose rate measured in the whole area of Tokyo in December 2014 was 60 nGy h(-1) (23-142 nGy h(-1)), which was 24% higher than the rate in 2003. Higher dose rates (>70 nGy h(-1)) were observed on the eastern and western ends of Tokyo; furthermore, the contribution ratio from artificial radionuclides ((134)Cs and (137)Cs) to ambient dose rate in eastern Tokyo was twice as high as that of western Tokyo. Based on the measured ambient dose rate, the effective dose rate after the accident was estimated to be 0.45 μSv h(-1) in Tokyo. This value was 22% higher than the value before the accident as of December 2014. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Absorbed dose rate in air in metropolitan Tokyo before the Fukushima Daiichi Nuclear Power Plant accident.

    Science.gov (United States)

    Inoue, K; Hosoda, M; Fukushi, M; Furukawa, M; Tokonami, S

    2015-11-01

    The monitoring of absorbed dose rate in air has been carried out continually at various locations in metropolitan Tokyo after the accident of the Fukushima Daiichi Nuclear Power Plant. While the data obtained before the accident are needed to more accurately assess the effects of radionuclide contamination from the accident, detailed data for metropolitan Tokyo obtained before the accident have not been reported. A car-borne survey of the absorbed dose rate in air in metropolitan Tokyo was carried out during August to September 2003. The average absorbed dose rate in air in metropolitan Tokyo was 49±6 nGy h(-1). The absorbed dose rate in air in western Tokyo was higher compared with that in central Tokyo. Here, if the absorbed dose rate indoors in Tokyo is equivalent to that outdoors, the annual effective dose would be calculated as 0.32 mSv y(-1). © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. The Role of Sub-National Actors in Climate Change Policy. The Case of Tokyo

    International Nuclear Information System (INIS)

    Roppongi, Hitomi

    2016-06-01

    Tokyo is known as a pioneer throughout the history of Japan's environmental policy, often being compared to California in the United States or Paris in France. Following the global trend of growing local initiatives tackling climate change, Tokyo introduced a cap-and-trade scheme in 2010 ahead of a national implementation. The Tokyo Cap-and-Trade Program is the first of its kind that regulates CO 2 emissions from all business sectors, where energy consumers are defined in terms of the business establishments they own. Tokyo's initiative is largely seen as a reaction to the modest national commitment, following the tradition of center-local rivalry. This study first explains the centre-local relationship in the history of Japan's environmental governance. It then analyzes the development of the Tokyo's flagship climate policy and its implications for national and other sub-national governments in Japan. The tactics used by the Tokyo Metropolitan Government to overcome business opposition typically seen in the introduction of GHG control, and future policy challenges are also discussed. The study finds that Tokyo's policy encourages behavioral changes and technological improvement in the business sector, going a step beyond the existing culture of energy conservation in Japan. An emission trading scheme is often associated with the collapse of carbon markets and the 'money game', rather than a practical tool to reduce CO 2 emissions, but the Tokyo Cap-and-Trade Program has demonstrated a policy impact that recasts such an image. A known case of policy diffusion to Saitama prefecture, an immediate neighbor of Tokyo with the fifth largest population in Japan, is also discussed to elaborate on the potential domestic diffusion of the policy. (author)

  6. Fibrosis unilateral congénita con enoftalmo y ptosis Congenital unilateral fibrosis with enophthalmos and ptosis

    Directory of Open Access Journals (Sweden)

    Yaimir Estévez Miranda

    2011-06-01

    Full Text Available El síndrome de fibrosis congénita es definido como un grupo de desórdenes congénitos raros caracterizado por la restricción de los músculos extraoculares y el reemplazo de los músculos por el tejido fibroso. Muchos autores utilizan la clasificación en la que se manifiesta en cinco tipos diferentes. El caso que se presenta corresponde a un niño quien desde el nacimiento está imposibilitado de elevar su ojo izquierdo. Al examen oftalmológico resultó positivo una ptosis palpebral en su ojo izquierdo, enoftalmo, limitación de la abducción, elevación en supraabducción y depresión. La agudeza visual en ambos ojos era de la unidad. El diagnóstico confirmado por genética fue de una fibrosis unilateral congénita con enoftalmo y ptosis. A pesar de tratarse de un desorden genético poco común, tiene formas esporádicas más raras aún. De ahí la importancia de presentar este caso, poco frecuente en nuestra práctica médica diaria.The syndrome of congenital fibrosis is defined like a group of rare congenital disorders characterized by restriction of extraocular muscles and replacement of fibrous tissue muscles. Many authors use the classification in which it is manifested in five different types. Present case is a child who from its birth can not to raise its left eye. The ophthalmic examination was positive to palpebral ptosis in this eye, enophthalmos, limitation of abduction, raise in supra-abduction and depression. The visual acuity in both eyes was of the unit. The diagnosis confirmed by genetics was that of a congenital unilateral fibrosis with enophthalmos and ptosis. Despite it is uncommon genetic disorder, it has more rare sporadic ways yet. Presentation of this uncommon case in our daily medical practice is very significant.

  7. Anestesia no cardiovascular en el paciente con cardiopatía congénita y flujo pulmonar aumentado

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2003-12-01

    Full Text Available Los lactantes y dentro de éstos los de menor edad y peso corporal, que padecen de cardiopatías congénitas con flujo pulmonar aumentado y son sometidos a anestesia para procedimientos quirúrgicos no cardiovasculares, tienen un gran riesgo anestésico, por lo que es necesario enfatizar que estos pacientes presentan habitualmente múltiples alteraciones anatómicas y de la fisiología cardiovascular con repercusión en diferentes órganos y sistemas, diversas enfermedades asociadas que empeoran el pronóstico y necesitan frecuentemente tratamiento médico con digitálicos, diuréticos y fármacos vasoactivos desde muy temprano, de modo que la evaluación preoperatoria, incluidas las investigaciones no invasivas, deben ser realizadas por cardiólogos experimentados y cuando se programan para procedimientos quirúrgicos, deben ser remitidos para un centro con recursos y la experiencia necesaria en el manejo de los pacientes con cardiopatías congénitas. Se presenta una revisión bibliográfica actualizada sobre el manejo anestésico de estos pacientes.Infants and among them the youngest and with the least body weight suffering from congenital heart diseases with increased pulmonary flow and who receive anesthesia to undergo noncardiovascular surgical procedures, are at a great anesthetic risk . That's why, it is necessary to make emphasis on the fact that these patients usually present multiple anatomical alterations and cardiovascular physiology disorders with repercussion on different organs and systems, diverse associated diseases that worsen the prognosis, and that they frequently need medical treatment with digitalis, diuretics and vasoactive drugs very early. Taking this into account, the preoperative evaluation, including non-invasive research should be carried out by experienced cardiologists and when they are scheduled for surgical procedures, they should be referred to a center with resources and the necessary experience in the

  8. Fauna of Cerambycidae (Insecta: Coleoptera) in Komaba Campus of the University of Tokyo, a highly urbanised area in Japan.

    Science.gov (United States)

    Kishimoto-Yamada, Keiko; Yamasako, Junsuke; Kato, Toshihide; Saito, Masayuki U; Ito, Motomi

    2017-01-01

    Urban green spaces play an important role in maintaining urban biodiversity in the Tokyo Metropolis, Japan. Plant-dependent insect assemblages such as Cerambycidae, in particular, are likely influenced by the existence of green spaces in Tokyo's urbanised environments. This study is the first comprehensive inventory of the cerambycid fauna in the Komaba Campus of the University of Tokyo. A cerambycid assemblage composed of a total of 25 species was recorded within the Komaba Campus site and compared to cerambycid assemblages in nine other green spaces distributed throughout Tokyo. The results indicated that the species number in the campus was similar to that recoded in a similar-sized green space in coastal Tokyo. Fewer cerambycid species were, however, found at the campus site than in larger-sized green spaces within Tokyo. Moreover, species compositions in urbanised areas were markedly different from those in suburbanised parks, mountains and forests within Tokyo.

  9. A highly attennuative zone beneath the Tokyo Metropolitan area.

    Science.gov (United States)

    Panayotopoulos, Y.; Hirata, N.; Sakai, S.; Nakagawa, S.; Kasahara, K.

    2014-12-01

    The intensities of seismic waves observed at the dense seismic array of the Tokyo Metropolitan Seismic Observation network (MeSO-net) inside the Kanto basin, display unusual distribution patterns. In several occasions, the highest intensities are not observed in the area above an earthquakes hypocenter but appear sifted more than 20 km away. In order to understand the source of this unusual intensity distribution pattern, it is crucial to understand how the waves attenuate before they reach the surface. The attenuation of seismic waves along their path is represented by the t∗ attenuation operator that can be obtained by fitting the observed seismic wave spectrum to a theoretical spectrum using an ω2 model. In order to create a high quality dataset, only 1449 earthquakes that are recorded with intensity greater than 0 in the Japan Meteorological Agency (JMA) intensity scale are selected from the JMA unified earthquake list from April 1st 2008 to October 2nd 2013. A grid search method is applied to determine the t∗ values by matching the observed and theoretical spectra. The t∗ data where then inverted to estimate a 3D Q structure with grid points set at a 10 km spacing. We implemented the 3D velocity model estimated by Nakagawa et al., 2012 and in addition we set the initial Q values at 100 for the 0 km grids and to 400 for the grids below them. The obtained model suggests average Q values of 50˜100 inside the Kanto basin. Furthermore, a low Q zone is observed in the area where the Philippine Sea plate meets the upper part of the Pacific sea plate. This area is located at approximately 40 km depth, beneath the north-east Tokyo and west Chiba prefectures and is represented by Q values Earthquakes occurring on the Pacific plate pass through this low Q area inside the Philippine sea plate and are attenuated significantly. The estimated attenuation distribution at the MeSO-net station for these earthquakes implementing our 3D Q model greatly coincides with the

  10. Enfermedades congénitas de la coagulación y manejo en Odontopediatría

    Directory of Open Access Journals (Sweden)

    Juan Manuel-Cortes-Ramírez

    2012-02-01

    Full Text Available El revisar un paciente en odontopediatría con hematomas y hemorragias es frecuente. El diagnóstico y el tratamiento dependen del conocimiento de los mecanismos normales de la hemostasia y de los laboratorios que los analizan1. Las manipulaciones en la cavidad bucal, máxime aquellas con extravasación de sangre, son un riesgo para los pacientes con trastornos de la coagulación, la prevención es la forma de evitar complicaciones, para ello debe disponer: de una historia clínica con énfasis en antecedentes personales y familiares de problemas hemorrágicos y del conocimiento de las patologías más frecuentes que lo originan así como su manejo2. Las hemorragias menores, son por factores locales, las graves por trastornos sistémicos de la hemostasia, como las coagulopatias congénitas2, grupo heterogéneo de enfermedades secundarias a alteraciones de las proteínas plasmáticas de la hemostasia primaria (ejemplo factor de von Willebrand, de la coagulación o de la fibrinólisis, defecto de un factor o combinación de 2 o más. Esta revisión se propone responder a estas interrogantes.

  11. Anomalía congénita de Cantrell: a propósito de un caso

    Directory of Open Access Journals (Sweden)

    Vladimir E Vargas-Rocha

    2010-08-01

    Full Text Available La Pentalogía de Cantrell es un defecto congénito que abarca el tórax y el abdomen y crea un espectro de anomalías entre las que se puede encontrar: la fisura del esternón, ectopia cardiaca, onfalocele, hernia diafragmática y cardiopatías congénitas. Presentamos el caso de un producto femenino, pre-término hija de mujer de 22 años de edad, que fue atendida en la “Clínica Cobija” por presentar un ligero dolor en el hipogastrio y un embarazo de 28 semanas. Se decide  realizar una cesárea, resultado de la cual se extrajo un feto con múltiples malformaciones; falta de formación de la porción inferior del esternón, falta de formación de la  pared abdominal anterior, pericardio visible a la inspección, estas anomalías son características de la pentalogía de Cantrell, además se pudo evidenciar anencefalia, amelia, sindactilia, fisura de paladar y labio leporino, membranas fetales anormales, feto con movimientos presentes, latido cardiaco regula y onfalocele. La paciente cursó sin complicaciónes post-quirúrgicas.

  12. Anomalía congénita de Cantrell: a propósito de un caso.

    Directory of Open Access Journals (Sweden)

    Vladimir E. Vargas-Rocha

    2009-01-01

    Full Text Available La Pentalogía de Cantrell es un defecto congénito que abarca el tórax y el abdomen y crea un espectro de anomalías entre las que se puede encontrar, la fisura del esternón, ectopia cardiaca, onfalocele, hernia diafragmática y cardiopatías congénitas. Presentamos el caso de un producto femenino, pre-término hija de mujer de 22 años de edad, que fue atendida en la "Clínica Cobija" por presentar un ligero dolor en el hipogastrio y un embarazo de 28 semanas. Se decide realizar una cesárea, resultado de la cual se extrajo un feto con múltiples malformaciones, falta de formación de la porción inferior del esternón, falta de formación de la pared abdominal anterior, pericardio visible a la inspección, estas anomalías son características de la pentalogía de Cantrell, además se pudo evidenciar anencefalia, amelia, sindactilia, fisura de paladar y labio leporino, membranas fetales anormales, feto con movimientos presentes, latido cardiaco regula y onfalocele. La paciente cursó sin complicaciónes post-quirúrgicas.

  13. Estrés oxidativo en las cardiopatías congénitas cianóticas

    Directory of Open Access Journals (Sweden)

    Dalyla Alonso Rodríguez

    2007-01-01

    Full Text Available Las cardiopatías y el infarto agudo de miocardio son procesos en cuya fisiopatología están presentes los radicales libres, que causan daños severos en la estructura del miocardio e involucran una cascada de eventos asociados con la pérdida de la integración de las membranas.Con el propósito de determinar la presencia de estrés oxidativo en las cardiopatías congénitas cianóticas, en un grupo de 20 pacientes pediátricos con esta afección se determinaron los niveles de antioxidantes séricos, como albúmina, ceruloplasmina, vitamina C, bilirrubina, ácido úrico, y de LDLox como marcador de daño oxidativo. Los resultados demostraron niveles bajos de vitamina C, hiperbilirrubinemia e hiperuricemia; las cifras de albúmina y ceruloplasmina no se modificaron, a diferencia de la LDLox, que evidenció la presencia de estrés oxidativo en estos pacientes.

  14. Strauss, R.: Symphony in F minor, Op. 12... Tokyo Metropolitan Symphony Orchestra / David Nice

    Index Scriptorium Estoniae

    Nice, David

    1994-01-01

    Uuest heliplaadist "Strauss, R.: Symphony in F minor, Op. 12... Tokyo Metropolitan Symphony Orchestra / Hiroshi Wakasugi. Denon CD CO-75 860 (54 minutes); Symphony - comparative version: SNO, Järvi" (8/93)(CHAN) CHAN 9166

  15. Interaction between two subducting plates under Tokyo and its possible effects on seismic hazards

    Science.gov (United States)

    Wu, Francis; Okaya, David; Sato, Hiroshi; Hirata, Naoshi

    2007-09-01

    Underneath metropolitan Tokyo the Philippine Sea plate (PHS) subducts to the north on top of the westward subducting Pacific plate (PAC). New, relatively high-resolution tomography images the PHS as a well-defined subduction zone under western Kanto Plain. As PAC shoals under eastern Kanto, the PHS lithosphere is being thrusted into an increasingly tighter space of the PAC-Eurasian mantle wedge. As a result, zones of enhanced seismicity appear under eastern Kanto at the top of PHS, internal to PHS and also at its contact with PAC. These zones are located at depths greater than the causative fault of the disastrous 1923 Great Tokyo ``megathrust'' earthquake, in the vicinity of several well-located historical, damaging (M6 and M7) earthquakes. Thus a rather unique interaction between subducting plates under Tokyo may account for additional seismic hazards in metropolitan Tokyo.

  16. Tokyo tähtsus üleilmse finantskeskusena väheneb / Kaja Koovit

    Index Scriptorium Estoniae

    Koovit, Kaja, 1968-

    2011-01-01

    Tokyo positsioon rahvusvahelise finantskeskusena sai riiki tabanud maavärina, tsunami ja radiatsiooni tõttu hoobi. Suured välispangad, investeerimisfondid ja maaklerfirmad toovad oma töötajaid Tokyost ära

  17. Tod's & United Bamboo + Toyo Ito & Vito Acconci + Omotesando & Daikanyama = Tokyo / Sergio Pirrone

    Index Scriptorium Estoniae

    Pirrone, Sergio

    2005-01-01

    Toyo Ito projekteeritud Itaalia jalatsi- ja kotifirmale kuuluvast Tod'si hoonest ning Vito Acconci kujundatud rõivakauplusest United Bamboo, mille interjöör meenutab kangast, Tokyos. Ill.: 8 värv. fotot, 9 korruste plaani

  18. Muusikamaailm : Wien Modern 2000. Muusikateater Huddersfieldis. Sibeliuse konkurss Helsingis. Penderecki uus teos Tokyos / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    Nüüdismuusikafestivalist "Wien Modern" 28. okt.-26. nov. Muusikalavastustest Huddersfieldi kaasaegse muusika festivalil. VIII Sibeliuse nim. rahvusvahelisest viiuldajate konkursist. 30. nov. toimus Tokyos K. Penderecki teose "Concerto grosso per tre violoncelli ed orchestra"

  19. Child Development in Okinawa Compared with Tokyo and Denver, and the Implications for Developmental Screening.

    Science.gov (United States)

    Ueda, Reiko

    1978-01-01

    Developmental differences in the Denver Developmental Screening Test items were demonstrated between samples of children from Okinawa (n=615) and Tokyo (n=1171), who were 16 days to 6 years old. Journal availability: see EC 112 661. (Author)

  20. Factor analysis on implementation of domiciliary dental care in Metropolitan Tokyo.

    Science.gov (United States)

    Hirata, SoIchiro; Sakayori, Takaharu; Maki, Yoshinobu; Takano, Naohisa; Ishii, Takuo

    2013-01-01

    The need for domiciliary dental care has increased with the aging of Japanese society. The Tokyo Metropolitan Government and Tokyo Dental Association conducted a survey of dental institutions within Tokyo in order to clarify which factors influenced implementation of domiciliary dental care by dental institutions. The proportion was significantly higher in (1) dentists in their 50s or older, (2) those working in cooperation with primary care physicians, (3) those providing dysphagia rehabilitation, (4) those who give information on prevention of aspiration pneumonia, (5) those who attended training on medical or domiciliary dental care for the elderly in need of nursing care, and (6) those who attended training workshops and seminars provided by the Tokyo Dental Association in 2010. In the logistic regression analysis, a significant odds ratio was obtained for the same items, excluding age. Attendance at training on medical or domiciliary dental care for the elderly in need of nursing care had the highest odds ratio. Those who attended any kind of training course implemented domiciliary dental care significantly more often. Training conducted by the Tokyo Metropolitan Center for Oral Health of Persons with Disabilities, Tokyo Dental Association, and local dental associations showed a significant odds ratio, with the highest by the Tokyo Dental Association. Traditionally, education on domiciliary dental care in the elderly is not provided at the college level. The present results indicate the importance of educating students with regard to the unique challenges such work poses. Attending seminars hosted by the Tokyo Dental Association also significantly influenced implementation of domiciliary dental care. This seems to be an important result, suggesting the effectiveness of training provided by dental associations with regard to the promotion of domiciliary dental care. This indicates the need for dental associations to provide such training throughout Japan.

  1. Lessons from Japan: Resilience after Tokyo and Fukushima

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    Michelle L. Spencer

    2013-01-01

    Full Text Available In the spring of 1995 Japan experienced the world’s first major terrorist attack using chemical weapons by a little-known religious cult called Aum Shinrikyo. The attack on the Tokyo subway, which killed 13 people, was the first lethal case of a non-state actor using a chemical agent against a civilian population. In March 2011, following a 9.0 magnitude earthquake in Japan, the Fukushima Daiichi nuclear reactor experienced a full meltdown releasing radiation into the surrounding area. The seemingly unhurried government reaction provided conflicting information to Japanese citizens, slowing evacuation and protective actions. Government failure is cited as a significant factor in the severity of the nuclear disaster in three investigations conducted after the incident. This article defines resilience and raises the question of whether the U.S. government has the ability to address the issues raised by the two case studies. There are four primary lessons of these two case studies from Japan: Trust is essential; two-way communications are vital; someone or something will always unexpectedly fail to act appropriately, while others will provide surprising support and; finally, recovery is long-term.

  2. Homelessness and Cognitive Impairment: An Exploratory Study in Tokyo, Japan.

    Science.gov (United States)

    Pluck, G; Nakakarumai, M; Sato, Y

    2015-09-01

    Homelessness has frequently been associated with neuropsychological impairment. This has been observed using general screening tests for dementia as well as tests of more focal abilities, particularly executive function. Most studies have been of homeless individuals from North America with none reported from Japan. In this exploratory study we interviewed a sample of 16 homeless adults from Tokyo, Japan, and performed tests of cognitive function, assessed head injury, addictive behaviours (drug use, gambling, alcohol abuse), and recorded details of homelessness history. The cognitive examination involved the Japanese Adult Reading Test to estimate premorbid intelligence quotient, the Wisconsin Card Sorting Test to measure frontal lobe-related cognitive function, and the Mini-Mental State Examination to measure global cognitive impairment associated with dementia. Among the 16 homeless individuals, 7 (44%) displayed global cognitive impairment. In addition, executive function tended to be poor. In contrast, estimated premorbid intelligence quotient was within the normal range. Substance abuse in general was not at a level to cause clinical concern, although a high level of pathological gambling was observed. There were no associations between cognitive function and clinical and addictive behaviour variables, although associations were noted between cognitive scores and time spent homeless. The results suggest high levels of neuropsychological impairment in this sample of homeless adults in Japan. Furthermore, cognitive impairment is acquired rather than developmental in origin, and is proportional to the length of time spent homeless.

  3. Radon anomalies in ground water before earthquakes in Tokyo

    International Nuclear Information System (INIS)

    Saito, Masaaki

    1992-01-01

    Radon contents in ground waters in Tokyo have been measured since 1976. The correlation between earthquake and radon anomaly will be evaluated easily, when both earthquakes and radon anomalies are a few. In addition, the high reliability of the correlation will be obtained, if an earthquake and an anomaly occur at almost same time. The six earthquakes occurred in 1976∼1990 were chosen based on the magnitude (≥6.0) and the epicentral distance (<100 km). Radon anomalies shortly before the six earthquakes were investigated at the stations where few anomalies have been detected. Anomalies which can be considered to relate with earthquakes appeared near around the dates of the Ibaraki-Chiba (1985) and the Yamanashi-Kanagawa (1983) earthquakes. The anomalies appeared in 6 d before ∼4 d after the earthquakes, and no other anomalies had appeared in over 600 d before the earthquakes. Then it is presumed that these anomalies would be earthquake precursors. The anomalies were found at the stations distributed in 50∼70 km epicentral distances and on the compress quadrants of the earthquake mechanism. (author)

  4. Reconstrucción genital integral en la Hiperplasia Suprarrenal Congénita: sensibilidad, estética y función (embarazo

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    A.A. Núñez Serrano

    Full Text Available La Hiperplasia Suprarrenal Congénita o Síndrome Adrenogenital es un cuadro clínico poco frecuente. Las anomalías que presenta van asociadas a síndromes que a veces son muy complejos, destacando, entre otros, el seudohermafroditismo femenino y el hermafroditismo verdadero. Las mujeres que la padecen presentan como alteración más evidente un clítoris aumentado de tamaño (megaloclítoris y otras alteraciones en los genitales externos. Ante estas pacientes es necesario realizar un diagnostico correcto mediante exploración física y otras pruebas complementarias: estudios genéticos, analíticos, hematológicos y urinarios. La corrección quirúrgica del megaloclítoris es necesaria no sólo para mejorar el aspecto de los genitales externos, sino también para que tanto la paciente como su familia se encuentren menos afectados psicológicamente. Existen varias técnicas quirúrgicas que intentan corregir esta malformación, como la amputación o clitorectomía total, la retroposición o enterramiento y la clitorectomía parcial selectiva. Todas ellas, junto con otras correcciones de los genitales externos afectados, han sido utilizadas hasta el día de hoy. Presentamos el caso de una paciente con Hiperplasia Suprarrenal Congénita por déficit del enzima 21-hidroxilasa. Describimos su clínica, la técnica quirúrgica aplicada en su caso y, sobre todo, dado la rareza de esta patología, comunicamos que, tras dos embarazos, los dos hijos nacidos, no presentaron la alteración congénita materna.

  5. Alteraciones neuropsicológicas en la hiperplasia adrenal congénita Neuropsychological disorders related to congenital adrenal hyperplasia

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    Yaser Ramírez Benítez

    2008-12-01

    Full Text Available INTRODUCCIÓN: la hiperplasia adrenal congénita engloba un conjunto de enfermedades genéticas de transmisión autosómica recesiva caracterizadas por un trastorno de la esteroidogénesis suprarrenal. Constituye un caso típico de daño cerebral por el efecto patológico de las hormonas sexuales en el sistema nervioso en desarrollo, y a esto se le suman las secuelas secundarias al cuadro grave de crisis adrenal que aparece en la forma clásica a los pocos días de vida. MÉTODOS: estudio de caso en un niño de 6 años de edad con antecedentes de hiperplasia adrenal congénita perdedora de sal. Se determinaron los puntos débiles y fuertes en el desarrollo a través de la batería neuropsicológica Luria Inicial. Como complementario a la evaluación se aplicó la Escala de Inteligencia de Weschler y el Cuestionario de Comportamiento Infantil para padres y profesores. RESULTADOS: el niño presenta un perfil neuropsicológico caracterizado por bajas puntuaciones en: motricidad manual, habilidades viso-espaciales, impulsividad, pobre vocabulario, dificultades en operaciones de cálculos sencillos, en el reconocimiento de objetos por el tacto sin la ayuda visual y en la rapidez de procesamiento. La capacidad de inteligencia está en límites normales con un rendimiento más bajo en la escala no verbal. En la escala de comportamiento se identificaron las dificultades en la atención y en el aprendizaje. CONCLUSIONES: el perfil neuropsicológico se caracteriza por tener bajas ejecuciones en tareas verbales, no verbales y en la velocidad de procesamiento. El tratamiento hormonal en los primeros días de nacido permite que el desarrollo siga un curso "normal", pero todo proceso tiene un costo que se refleja en la adquisición de habilidades psicológicas superioresCongenital adrenal hyperplasia includes a series of genetic diseases of autosomal recessive transmission characterized by a disorder of suprarenal esteroidogenesis. This is a typical case of

  6. New tomographic images of P- , S- wave velocity and Q on the Philippine Sea Slab beneath Tokyo: Implication to seismotectonics and seismic hazard in the Tokyo metropolitan region

    Science.gov (United States)

    Hirata, Naoshi; Sakai, Shin'ichi; Nakagawa, Shigeki; Panayotopoulos, Yannis; Ishikawa, Masahiro; Sato, Hiroshi; Kasahara, Keiji; Kimura, Hisanor; Honda, Ryou

    2013-04-01

    The Central Disaster Management Council of Japan estimates the next great M7+ earthquake in the Tokyo metropolitan region will cause 11,000 fatalities and 112 trillion yen (1 trillion US) economic loss at worst case if it occur beneath northern Tokyo bay with M7.3. However, the estimate is based on a source fault model by conventional studies about the PSP geometry. To evaluate seismic hazard due to the great quake we need to clarify the geometry of PSP and also the Pacific palate (PAP) that subducs beneath PSP. We identify those plates with use of seismic tomography and available deep seismic reflection profiling and borehole data in southern Kanto area. We deployed about 300 seismic stations in the greater Tokyo urban region under the Special Project for Earthquake Disaster Mitigation in Tokyo Metropolitan Area. We obtain clear P- and S- wave velocity (Vp and Vs) and Q tomograms which show a clear image of PSP and PAP. A depth to the top of PSP, 20 to 30 kilometer beneath northern part of Tokyo bay, is about 10 km shallower than previous estimates based on the distribution of seismicity (Ishida, 1992). This shallower plate geometry changes estimations of strong ground motion for seismic hazards analysis within the Tokyo region. Based on elastic wave velocities of rocks and minerals, we interpreted the tomographic images as petrologic images. Tomographic images revealed the presence of two stepwise velocity increase of the top layer of the subducting PSP slab. Rock velocity data reveals that subducting PSP crust transforms from blueschists to amphibolites at depth of 30km and amphibolites to eclogites at depth of 50km, which suggest that dehydration reactions occurs in subducting crust of basaltic compositions during prograde metamorphism and water is released from the subducting PSP crust. Tomograms show evidence for a low-velocity zone (LVZ) beneath the area just north of Tokyo bay. A Q tomogram show a low Q zone in PSP slab. We interpret the LVZ as a

  7. Prevalencia de sífilis congénita en tres hospitales públicos de Baja California, México, 2012-2015

    Directory of Open Access Journals (Sweden)

    Jorge Luis Arellano-Estrada

    2017-08-01

    Full Text Available Señor editor: Presentamos los resultados de un estudio descriptivo con base en datos de estudio epidemiológico (EE de caso para sífilis congénita (SC. El formato contiene antecedentes, síntomas, evolución y asociación con factores de riesgo (FR del binomio madre-hijo. El análisis se basa en identificar la prevalencia de SC en los Hospitales de la Secretaría de Salud (SSa de los municipios de Tijuana, Playas de Rosarito y Tecate, Baja California, de 2012 a 2015.

  8. Congenital hepatic fibrosis associated with von Recklinghausen's disease Fibrosis hepática congénita asociada a enfermedad de von Recklinghausen

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    O. A. Jorge

    2006-09-01

    Full Text Available Congenital hepatic fibrosis is characterized by a ductal plate malformation with duct-like structures and fibrosis. It manifests clinically with portal hypertension and may be associated with multiple congenital defects. We present the case of a 16-year-old male with splenomegaly, leukopenia and thrombocytopenia, esophageal varices, and a histopathological diagnosis of congenital hepatic fibrosis. He exhibits "café au lait' spots and "Lisch' nodules, with a diagnosis of von Recklinghausen's disease. Congenital hepatic fibrosis belongs to the so-called fibropolycystic diseases, in which there is a disordered interaction between cells and the extracellular matrix. Von Recklinghausen's disease affects tissues derived from the neural crest and its diagnosis is based on clinical criteria. It is associated with multiple diseases. We describe its association with congenital hepatic fibrosis for the first time.La fibrosis hepática congénita se origina como consecuencia de una malformación de la placa ductal con estructuras tipo ductales acompañadas de fibrosis. Se manifiesta con hipertensión portal y puede asociarse a múltiples defectos congénitos. Presentamos un varón de 16 años con esplenomegalia, leuco- y plaquetopenia, varices esofágicas y diagnóstico histopatológico de fibrosis hepática congénita. La exploración física mostraba la existencia de manchas de "café con leche' y nódulos de "Lisch' con diagnóstico de enfermedad de von Recklinghausen. La fibrosis hepática congénita forma parte de las enfermedades fibropoliquísticas donde existiría una alteración en la interacción entre las células y la matriz extracelular. La enfermedad de von Recklinghausen afecta a los tejidos derivados de la cresta neural y su diagnóstico se basa en criterios clínicos. Se asocia a múltiples patologías. Presentamos por primera vez su asociación con fibrosis hepática congénita.

  9. Prevalencia de sífilis congénita en tres hospitales públicos de Baja California, México, 2012-2015

    OpenAIRE

    Jorge Luis Arellano-Estrada; Cinthia Selene López-Lara; Erendida Barreras-Valenzuela

    2017-01-01

    Señor editor: Presentamos los resultados de un estudio descriptivo con base en datos de estudio epidemiológico (EE) de caso para sífilis congénita (SC). El formato contiene antecedentes, síntomas, evolución y asociación con factores de riesgo (FR) del binomio madre-hijo. El análisis se basa en identificar la prevalencia de SC en los Hospitales de la Secretaría de Salud (SSa) de los municipios de Tijuana, Playas de Rosarito y Tecate, Baja California, de 2012 a 2015.

  10. Síndrome de rubéola congénita en diecisiete hospitales del Perú, 1998-2000

    OpenAIRE

    Blitchtein-Winicki, Dora; Gonzales, Paola; Rodríguez, Rosario; Matos, Javier; Santillán, Marta; Soto, Carlos; Silva, Nazario; Narváez, Mario; Gonzales, Jorge; Chávez, Jaime; Gonzáles, Maribel; Del Aguila, Roberto; Suárez-Ognio, Luis

    2013-01-01

    Objetivo: Determinar la presencia de casos de síndrome de rubéola congénita (SRC) en Hospitales Nacionales e Institutos Especializados del Perú. Diseño: Transversal, descriptivo. Material y Métodos: Se revisó historias clínicas de niños hospitalizados entre enero de 1998 y junio de 2000 en 17 hospitales ubicados en 7 departamentos del Perú, niños que presentaron cuando menos alguno de los siguientes diagnósticos: catarata o glaucoma congénitos, retinitis pigmentosa, malformación cardíaca cong...

  11. Anomalías congénitas de la válvula mitral en adultos: Estudio clínico-ecocardiográfico

    OpenAIRE

    Espinola-Zavaleta,Nilda; Yabur-Espitia,Mirna

    2010-01-01

    Introducción: Las anomalías congénitas de la válvula mitral (ACVM) comprenden una amplia gama de anormalidades de las valvas y del aparato subvalvular y su presentación en la vida adulta no es frecuente. Objetivo: En el presente trabajo, evaluamos los aspectos clínicos, ecocardiográficos y el tratamiento de cinco pacientes adultos con ACVM. Métodos: A todos los sujetos se les realizó historia clínica, electrocardiograma, radiografía de tórax y ecocardio-grama. Resultados: Dos pacientes estuvi...

  12. Prevalencia de malformaciones congénitas detectadas al nacimiento en un hospital de segundo nivel en Sinaloa

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    Ana Beatriz Calderón-Alvarado

    2017-11-01

    Full Text Available INTRODUCCIÓN: la prevalencia de malformaciones congénitas (MC detectadas al nacimiento es de 2 a 5.5 neonatos vivos, variando significativamente según las características de la población y metodología del estudio.   OBJETIVO: determinar la prevalencia y tipos de MC en los recién nacidos atendidos por el servicio de neonatología en un periodo de un año.   MATERIAL Y MÉTODOS: estudio transversal. Se revisaron expedientes clínicos de recién nacidos vivos atendidos en el servicio de neonatología de nuestra institución durante el año 2015. Se incluyeron neonatos con alteraciones morfológicas detectadas al nacimiento y/o antes del alta hospitalaria, referidas en el expediente.   RESULTADOS: se detectaron 117 MC en 98 neonatos, de un total de 4,097 estudiados, obteniendo una prevalencia de 2.39% en el análisis por individuo y de 2.85%, tomando en cuenta el total de MC. Los aparatos y sistemas más afectados fueron: genitourinario (29.1%, osteomuscular (21.4% y circulatorio (16.2%. Las MC más frecuentes fueron: criptorquidia (14.5%, hipospadias (12.8% y anquiloglosia (10.3%. CONCLUSIÓN: la tasa de prevalencia de MC fue de 23.9 por 1,000 recién nacidos vivos, lo cual coincide con la reportada en el resto del mundo, siendo el aparato genitourinario el más afectado y la criptorquidia la MC más frecuente en nuestra población.

  13. Seasonal Changes in Hospital Admissions for Pulmonary Embolism in Metropolitan Areas of Tokyo (from the Tokyo Cardiovascular Care Unit Network).

    Science.gov (United States)

    Mizuno, Atsushi; Takeuchi, Ayano; Yamamoto, Takeshi; Tanabe, Yasuhiro; Obayashi, Toru; Takayama, Morimasa; Nagao, Ken

    2015-12-15

    Although several studies have shown the relation between temperature/atmospheric pressure and pulmonary embolism (PE), their results are inconsistent. Furthermore, diurnal temperature range (DTR) and diurnal pressure range (DPR) were not fully evaluated for their associations with hospital admissions for PE. Study subjects comprised cases of 1,148 PE treated at institutions belonging to the Tokyo Cardiovascular Care Unit Network from January 2005 to December 2012. Patient data were combined with a variety of daily local climate parameters obtained from the Japan Meteorological Agency. Every 1°C increase in the DTR at lag0 corresponded to an increased relative risk of hospital admission for PE (odds ratio [OR] 1.036, 95% confidence interval [CI] 1.003 to 1.070). In the cooler season (November to April), an increase of 1 hPa (barometric pressure) in the DPR at lag4 and lag5 was associated with an increased relative risk of hospital admission for PE (OR 1.042, 95% CI 1.007 to 1.077 and OR 0.952, 95% CI 0.914 to 0.992, respectively). An increase in the PE hospitalization rate was seen only in the cool season. Using a metropolitan database, we showed that DTR and DPR have different impacts on hospital admissions for PE. In conclusion, we found that an increase in the DTR increases the PE hospitalization rate, especially during the cooler season. The impact of DTR and DPR on PE incidence and related hospitalizations needs to be further evaluated. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Useful of Tokyo guidelines in the diagnosis of acute cholecystitis. Anatomopathologie correlationship.

    Science.gov (United States)

    Janikow, Christian; Corti, Edgardo; Menso, Nicolás; Moretti, Gastón; Alé, Martín; Sánchez, Martín; Lada, Paul Eduardo

    2017-01-01

    In the year 2007 a group of experts come together to discuss criteria for acute cholecystitis and to establish therapeutic guidelines and states of gravity in this disease. we correlated the criteria of the Tokyo Guidelines 2007 with the anatomopathology study of the surgical specimen. Service of Urgencies of the National Clinic Hospital in Córdoba, Argentine. We studied 324 patients (120 male and 204 female) older than 15 years and without limits of age with the criteria of acute cholecystitis a cord to the Tokyo guidelines 2007. 202 patients had a preoperative diagnosis of chronic cholecystitis and 89 of acute cholecystitis, all received cholecystectomy and studied the operative specimen in the anatomopathology department. Anatomopathology criteria for acute cholecystitis were the presence of polimorpho nuclear cells (PMN), for acute exacerbation of chronic cholecystitis the presence of PMN and monomorpho nuclear cells (MN), and for chronic cholecystitis the presence of MN with or without fibrosis. This work showed 82,14% of sensitivity for the diagnostic criteria of Tokyo guidelines, 74,03% of specificity, and positive predictive value of 46%. With the Bayes Theorem the predictive value in Córdoba city was 18,49%. There is an important difference in the specificity and positive predictive value between our work and the Tokyo guidelines for acute cholecystitis. There is an important group of patients in our work with acute exacerbation of chronic cholecystitis that is not classified in the diagnostic criteria for acute cholecystitis of Tokyo guidelines.

  15. ASSOCIAÇÃO DAS MALFORMAÇÕES CONGÊNITAS COM VARIÁVEIS NEONATAIS E MATERNAS EM UNIDADES NEONATAIS NUMA CIDADE DO NORDESTE BRASILEIRO

    Directory of Open Access Journals (Sweden)

    Fabíola Chaves Fontoura

    2014-01-01

    Full Text Available Malformaciones congénitas ocurrir debido a factores genéticos, ambientales, mistos o por causas desconocidas. Se objetivó investigar la relación entre tipo de malformación congénita, variables neonatales y maternas. Estudio prospectivo, cuantitativo, realizado en tres unidades neonatales públicas en Fortaleza-CE, Brasil. Los datos fueron recolectados del sistema de registro de 159 recién nacidos malformados y analizados por medio del test Chi cuadrado (χ 2 , nivel de significancia de 5% ( p <0,05. Prevalecieron 85 (53% recién nacidos del sexo masculino, 91 (57% a término y 82 (52% con peso entre 2500g y 3999g. Sobresalieron malformaciones del sistema nervoso central y óseo muscular. Variables como sexo, edad gestacional, peso al nascer, uso de drogas, edad materna, renta familiar, nivel de instrucción y cantidad de hijos demostraron significancia estadística, cuando asociadas a las categorías de malformaciones (p<0,05. Factores maternos y neonatales presentaron relación con el tipo de malformaciones, datos relevantes para el cuidado de enfermería junto al neonato.

  16. ANO IMPERFORADO Y CATARATA CONGÉNITA EN EL SÍNDROME DE JOHNSON-MCMILLIN HALLAZGOS NO REPORTADOS O ADQUIRIDOS

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    Francisco Cammarata-Scalisi

    2013-08-01

    Full Text Available Johnson et al. en 1983, describieron 16 casos en una familia que presentó alopecia, anosmia o hiposmia, sordera de conducción, microtia y/o atresia de conducto auditivo externo e hipogonadismo hipogonadrotófico, que mostraba un patrón de herencia autosómico dominante, con expresividad variable. Otras manifestaciones menos constantes incluyeron asimetría facial, retardo mental, cardiopatía congénita, paladar hendido y estenosis de coanas. Aparte de estos casos, solo siete pacientes con el síndrome de Johnson-McMillin han sido reportados hasta el momento. La patogénesis de esta entidad es incierta y el diagnóstico diferencial es amplio. Se describe un nuevo caso en una lactante femenina de ocho meses en el cual la alopecia universal, la microcefalia, la parálisis facial, el paladar blando hendido y las alteraciones a nivel de pabellones auriculares fueron significativos para establecer el diagnósticoLa paciente también presentó otros signos clínicos no asociados al síndrome, como el ano imperforado y la catarata congénita bilateral.

  17. ANO IMPERFORADO Y CATARATA CONGÉNITA EN EL SÍNDROME DE JOHNSON-MCMILLIN HALLAZGOS NO REPORTADOS O ADQUIRIDOS

    Directory of Open Access Journals (Sweden)

    Francisco Cammarata-Scalisi

    2012-01-01

    Full Text Available Johnson et al. en 1983, describieron 16 casos en una familia que presentó alopecia, anosmia o hiposmia, sordera de conducción, microtia y/o atresia de conducto auditivo externo e hipogonadismo hipogonadrotófico, que mostraba un patrón de herencia autosómico dominante, con expresividad variable. Otras manifestaciones menos constantes incluyeron asimetría facial, retardo mental, cardiopatía congénita, paladar hendido y estenosis de coanas. Aparte de estos casos, solo siete pacientes con el síndrome de Johnson-McMillin han sido reportados hasta el momento. La patogénesis de esta entidad es incierta y el diagnóstico diferencial es amplio. Se describe un nuevo caso en una lactante femenina de ocho meses en el cual la alopecia universal, la microcefalia, la parálisis facial, el paladar blando hendido y las alteraciones a nivel de pabellones auriculares fueron significativos para establecer el diagnósticoLa paciente también presentó otros signos clínicos no asociados al síndrome, como el ano imperforado y la catarata congénita bilateral.

  18. Correlación clínico-radiológica de las anomalías congénitas excavadas del disco óptico

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    Lester Pola Alvarado

    Full Text Available Introducción: el diagnóstico de las anomalías congénitas excavadas del nervio óptico se ha beneficiado con la introducción y desarrollo de las técnicas imagenológicas; particularmente en los casos atípicos o con alteraciones oculares asociadas, donde el examen clínico no puede ser concluyente. Caso clínico: se presenta un paciente con una anomalía congénita del nervio óptico y se discuten las características clínico-imagenológicas que sustentan su diagnóstico diferencial. Se recomienda la evaluación conjunta, por parte de oftalmólogos y radiólogos, de pacientes con estas anomalías; sobre todo en aquellos donde las presentaciones fundoscópicas no son específicas. Conclusiones: el diagnóstico nosológico correcto garantiza una adecuada orientación sobre alteraciones sistémicas relacionadas y patrones de herencia, si los hay.

  19. Potential for air quality improvement in the Tokyo metropolitan area from use of hydrogen fuel

    International Nuclear Information System (INIS)

    Kruger, Paul; Murdock, Mork

    1998-01-01

    A revised estimation has been made of the local air quality improvement that can be achieved in Tokyo as a byproduct of a word-wide hydrogen energy economy based on global reduction of CO2 emission from fossil fuels. The study for the WE-NET Project in Japan examined the potential for reduction in nitrogen oxide emission with hydrogen fuel in the Tokyo metropolitan area where sufficient data exist on trends in population, vehicle registrations, traffic activity, and exhaust emissions. A dynamic model was developed to extrapolate the trends in these data to estimate future NOx emission rates in comparison to regulatory scenarios based on policy and technical decisions of the Tokyo Metropolitan Government for improvement of air quality in the metropolitan area. The results of the model show significant potential for reduction of NOx emission by the year 2020 with a concomitant reduction in mean roadside NOx concentration. (author)

  20. The Aftermath of the Fukushima Daiichi Accident: a Perspective from the British Embassy in Tokyo.

    Science.gov (United States)

    Oppenheim, R J; Franklin, K C

    2016-04-01

    The British Embassy in Tokyo was at the heart of providing information in the immediate aftermath of the Fukushima Daiichi accident. Richard Oppenheim, who was present at the time, and Keith Franklin, who joined the Embassy shortly afterwards, give their perspectives on communicating information on radiation to the public and what lessons can be learned. Richard Oppenheim was head of the Climate Change and Energy team at the British Embassy in Tokyo from 2011 to 2015 and part of the Embassy team responding to the crisis. He travelled to Sendai on 12 March 2011. Keith Franklin has been on secondment to the British Embassy in Tokyo from the National Nuclear Laboratory since the accident at Fukushima Daiichi.

  1. Fifty years experiences in nuclear engineering education at Tokyo Institute of Technology

    International Nuclear Information System (INIS)

    Fujii, Yasuhiko; Saito, Masaki; Aritomi, Masanori

    2008-01-01

    Nuclear engineering education has been initiated in 1957 at the graduate school of Tokyo Institute of Technology. Educational activities have been conducted for fifty years under the support of the Research Laboratory for Nuclear Reactors. In the past fifty years, about 1000 Master students and 200 Doctoral students and 200 Doctoral students graduated from our Nuclear Engineering Department at Tokyo Institute of Technology. Many of them found their jobs in nuclear industries and institutes. International course of nuclear engineering was initiated in 1994, and so far about 90 students from 15 overseas countries have graduated from our Master and Doctoral Programs. In 2003, our proposal of 'Innovative Nuclear Energy System for the Sustainable World' was adopted as the Center of Excellent Program sponsored by Ministry of Education, Science and Technology. Recently a collaborative education network has been developed among Kanazawa University, Fukui University, Ibaraki University, Okayama University, Tokyo Institute of Technology and Japan Atomic Energy Agency. (author)

  2. THE SPATIAL DEVIATION OF CONCENTRATED HEAVY RAIN IN TOKYO - USING DETAILED URBAN GEOMETRIC DATA -

    Science.gov (United States)

    Fukumoto, Eriko; Nakayoshi, Makoto; Kanda, Manabu; Sone, Atsushi

    Unusual weather, such as urban localized heavy rain, has become a serious problem lately due to the disasters caused by it. In this work, the latest data of Tokyo, Japan is used with past ones to see the dramatic change in urban geometry and to understand the spatial anomaly of concentrated heavy rain in summer time. As a result, the urban geometry in Tokyo has indeed grown. Adding the displacement height to actual elevation gives the "affective" elevation, which is very low along the bay and abruptly increases as it approaches the western areas. This sudden increase in elevation seems to correspond with where the anomaly of rainfall for concentrated heavy rain becomes positive. In addition, the 9-year data from the River Bureau shows the shift of positive anomaly into the urban area. Finally, the spatial deviation, driven by the Amesh data, indicates the strong relationship between urbanization and precipitation in Tokyo.

  3. 32. Ampliación de la raíz aórtica mediante técnica de manouguian en cardiopatías congénitas del adulto

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    M.T. González López

    2012-04-01

    Conclusiones: En casos seleccionados, la ampliación de raíz aórtica mediante técnica de Manouguian resulta eficaz en el manejo de la patología valvular asociada a cardiopatías congénitas del adulto.

  4. 231. Cirugía cardíaca en adultos con cardiopatías congénitas: ¿qué pacientes y patologías intervenimos actualmente?

    Directory of Open Access Journals (Sweden)

    E.C. Ruiz-Solano

    2012-04-01

    Conclusiones: La cirugía congénita sobre pacientes adultos representa una actividad de relevancia en la cirugía cardíaca de hoy día. Nuestros resultados evidencian que este tipo de intervenciones se puede llevar a cabo con una baja morbimortalidad.

  5. Tortícolis muscular congénita: punto de vista del cirujano plástico

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    F.J. Villegas-Alzate

    2014-03-01

    Full Text Available La tortícolis muscular congénita es una entidad frecuente, presente al nacimiento como una banda fibrosa o tumor en la región del músculo esternocleidomastoideo, que produce cambios restrictivos reflejados en trastornos progresivos del crecimiento y posición de la cabeza y en la rotación y flexión del cuello. El diagnóstico y tratamiento oportunos con fisioterapia y aparatología pueden evitar su secuencia de asimetría craneofacial y daño ocular, de difícil corrección una vez instaurados. Los casos que no responden al tratamiento médico inicial se benefician de cirugía. Presentamos la experiencia quirúrgica con 16 pacientes entre 9 y 32 años con seguimiento de entre 10 semanas y 15 años. El tratamiento quirúrgico consistió en 3 tenotomías de las inserciones del músculo esternocleidomastoideo a través de abordaje directo por dos incisiones pequeñas. Cuantificamos la mejoría de la posición de la cabeza por mediciones angulares en las fotografías pre y postoperatorias en vistas anterior y posterior, demostrando correcciones de entre el 53 y el 100% con promedio del 83% . En algunos casos medimos la movilidad del cuello con un transportador de ángulos confeccionado en consulta. En todos los casos logramos mejoría sustancial, sin complicaciones y con cicatrices aceptables; la columna lateral del cuello en el sitio del músculo seccionado recuperó su continuidad, sin percepción de corte abrupto, depresión o hundimiento. No observamos correlación entre la mejoría lograda y la severidad de la deformidad, ni tampoco con la edad del paciente en el momento de la cirugía, ya que a pesar de que en algunos casos había finalizado el crecimiento y el estado era avanzado, la mejoría fue buena.

  6. Sífilis congénita en el Hospital Universitario de Santander, Bucaramanga (Colombia, 2006 - 2007

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    Cecilia del Carmen Matos Mareño

    2013-12-01

    Full Text Available Antecedentes. La sífilis congénita (SC aumenta en nuestro país a pesar de existir un programa diseñado para su control. Se requiere conocer las características de los afectados y sus padres, para implementar medidas de control. Objetivo. Caracterizar los casos de SC atendidos en el Hospital Universitario de Santander, Bucaramanga (Colombia, entre Junio/2006 y Septiembre/2007. Materiales y métodos. Estudio de corte transversal prospectivo. Se analizaron variables sociodemográficas y clínicas de los recién nacidos y sus padres. Resultados. Se presentaron 36 recién nacidos (RN con SC. Nueve sintomáticos (25%, 6 con compromiso del sistema nervioso central (16.7%; 2 murieron (5.6%. En 12 casos (33.3% las madres no hicieron control prenatal; 16 (44.4% no aparecen inscritas al sistema de seguridad social en salud. Tres madres (8.3% infectadas por VIH; 6 (16.7% con más de 9 compañeros sexuales y 10 (27.8% con un compañero sexual; 8 (22.2% usó drogas ilícitas. El diagnóstico de sífilis fue hecho en el tercer trimestre del embarazo en 15 casos (41.7% y 14 (38.9% en postparto. El 47.2% de las madres no recibió tratamiento durante el embarazo (17 casos; 25 padres (69.5% no lo recibieron. Conclusiones. Pese a que la SC es una enfermedad prevenible, en el Hospital Universitario de Santander se encontraron 36 casos entre junio de 2006 a septiembre 2007. Sobresalen factores inherentes a la madre, a su entorno y al acceso al servicio de salud que hacen que la SC aumente en nuestro medio. Para modificar la incidencia de la SC es mandatorio mejorar la calidad del control prenatal, garantizar el acceso y captación de las gestantes de manera oportuna, lograr adherencia a los protocolos de manejo por parte de las IPS para poder mejorar la calidad de vida de la infancia en Santander

  7. Factors Contributing to Plate Waste among Elementary School Children in Tokyo, Japan: Application of the Theory of Planned Behavior

    Science.gov (United States)

    Abe, Keina; Akamatsu, Rie

    2013-01-01

    Purpose/Objectives: The purpose of this study was to identify the aspects of the Theory of Planned Behavior with the greatest relevance to plate waste (PW) among elementary school children in Tokyo, Japan. Methods: A total of 111 fifth- and sixth-grade students at an elementary school in Tokyo, Japan responded to a self-report questionnaire. The…

  8. How fast do Tokyo and New York stock exchanges respond to each other? An analysis with high-frequency data

    NARCIS (Netherlands)

    Tsutsui, Y.; Hirayama, K.

    2010-01-01

    This paper uses one-min returns on the TOPIX and S&P500 to examine the efficiency of the Tokyo and New York Stock Exchanges. Our major finding is that Tokyo completes reactions to New York within six min, but New York reacts within fourteen min. Dividing the sample period into three subperiods, we

  9. Supervivencia con oclusión traqueal fetoscópica versus manejo expectante post natal en el tratamiento de la hipoplasia pulmonar secundaria a hernia diafragmática congénita aislada

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    Rubén Darío Aguirre Urrea

    2014-09-01

    Full Text Available Antecedentes: La Hernia Diafragmática Congénita es el defecto más común de la formación y cierre del diafragma que permite el paso de las vísceras abdominales a la cavidad torácica generando dos consecuencias graves que aumentan el riesgo de mortalidad de los neonatos: hipoplasia e hipertensión pulmonar del lado afectado que determinan la gravedad de la anomalía. Objetivo: Comparar la supervivencia en los pacientes con hipoplasia pulmonar secundaria a Hernia Diafragmática Congénita aislada tratados con Oclusión Traqueal Fetoscópica versus la supervivencia en los tratados con manejo expectante post natal. Método: Se realizó una revisión integradora de la literatura científica de las bases de datos LILACS, SciELO, Cochrane Library, PubMed y Google Académico. Resultados: Se seleccionaron para ser analizados 11 estudios, entre los cuales, 6 fueron realizados en Europa: Inglaterra, Bélgica y España; 3 en Colombia, 1 en Brasil y 1 en Estados Unidos entre 1990 y 2013. Conclusiones: El pronóstico y las probabilidades de supervivencia mejoran sustancialmente cuando se opta por la Oclusión Traqueal Fetoscópica como tratamiento de la hipoplasia pulmonar secundaria a hernia diafragmática congénita aislada. Palabras clave: Hernia diafragmática congénita; oclusión traqueal fetoscópica; hipoplasia pulmonar, cirugía fetal, anomalías congénitas.

  10. Macroglosia congénita: características clínicas y estrategias de tratamiento en la edad pediátrica

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    Paulina María Núñez-Martínez

    2016-05-01

    Full Text Available La macroglosia congénita es una condición que se caracteriza por una lengua que en posición de reposo protruye más allá del borde alveolar; se ha clasificado en dos categorías: verdadera, que puede ser congénita o adquirida, y relativa. Debido a la asociación de esta alteración con múltiples causas, su incidencia es variable. Es más frecuente que la macroglosia se asocie con el síndrome de Beckwith-Wiedemann, con las mucopolisacaridosis y con la enfermedad de Pompe, y con menor frecuencia a linfangioma, hemangioma o hipertrofia muscular aislada. La macroglosia se caracteriza por una lengua alargada, engrosada o ancha, protruida crónicamente en reposo, con presencia o no de fisuras y úlceras, alteraciones del lenguaje, dificultad para la alimentación y deglución, sialorrea e infecciones recurrentes de la vía respiratoria superior u obstrucción de la misma. Su valoración en niños debe iniciarse con una historia clínica y exploración física completas y con la elaboración de un árbol genealógico de al menos tres generaciones, además de investigar la presencia o no de una entidad sindrómica. Se han propuesto más de 20 técnicas quirúrgicas para resolver la macroglosia congénita; sin embargo, a la fecha no existe consenso para la aplicación de una técnica en particular para reducir su tamaño. En esta revisión se pretende destacar los aspectos clínicos y quirúrgicos de la macroglosia, desde la perspectiva de pediatras no cirujanos y genetistas, dirigido a la comunidad de especialistas médicos que atiende a estos pacientes incluyendo a los cirujanos maxilofaciales que atienden a estos pacientes.

  11. Características clínicas y epidemiológicas de la catarata congénita e infantil

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    Merixy Charón Milián

    2012-12-01

    Full Text Available Introducción: la catarata de cualquier etiología es la una de las causas más importantes de ceguera tratable en los niños. Objetivos: caracterizar, desde los puntos de vista clínico y epidemiológico, la catarata congénita e infantil. Métodos: se realizó un estudio observacional, descriptivo y retrospectivo en el Hospital Pediátrico "William Soler", entre enero de 2004 y junio de 2006. Se analizaron las variables: edad, sexo, procedencia, vía de captación, síntomas, factores de riesgo, localización, etiología probable y lateralidad de la catarata, alteraciones oculares asociadas y visión posquirúrgica. Los resultados se expresaron en media y porcentaje. Resultados: la edad promedio fue de 4,9 años y para menores de 1 año de 6,6 meses. Predominaron los varones (60,32 %, los pacientes de La Habana (25,4 %, la remisión médica como vía de captación (71,43 %, la leucocoria (30,15 %, la presencia de anomalías congénitas múltiples (34,92 %, la localización central de la catarata (44,44 %, la causa idiopática (41,27 % y la bilateralidad (66,67 %. El 34,92 % de los pacientes tenía asociada otra anomalía ocular, y el 59,04 % de los ojos operados alcanzaron visión entre 0,7 y 1,0. Conclusiones: en la serie analizada predominaron los lactantes menores de 2 meses y los varones, los pacientes de La Habana, la remisión médica, la leucocoria y las anomalías congénitas múltiples asociadas, la localización central y la posible etiología; en las bilaterales, el origen hereditario; y en las unilaterales, la causa desconocida. La mejoría visual posquirúrgica fue mayor a medida que disminuyó la edad del paciente al momento de realizar la cirugía.

  12. Hernia diagfragmática congénita derecha en el Hospital Universitario de Santander Right congenital diaphragmatic hernia at the Hospital Universitario de Santander

    Directory of Open Access Journals (Sweden)

    Julio César Mantilla

    2010-08-01

    Full Text Available Introducción: La hernia diafragmática del lado derecho es una variable poco frecuente de los defectos congénitos diafragmáticos que permiten el paso del contenido abdominal a la cavidad torácica, causando graves trastornos en el desarrollo pulmonar fetal. Objetivo: Describir las características patológicas encontradas en la autopsia perinatal de un paciente con Hernia diafragmática congénita derecha en el Hospital Universitario de Santander. Caso clínico: Neonato de 35 semanas de gestación con diagnóstico prenatal de Hernia Diafragmática Congénita, quien fallece minutos después de su nacimiento debido a insuficiencia respiratoria aguda. En los hallazgos de autopsia se encuentra ausencia de la mayor parte del hemidiafragma derecho, herniación del contenido abdominal al tórax y una severa hipoplasia pulmonar. Conclusion: La Hernia diafragmática congénita del lado derecho se asocia con alta mortalidad neonatal y los hallazgos encontrados en el presente caso se correlacionan con los graves defectos estructurales pulmonares que se describen en otros casos reportados en la literatura. Salud UIS 2010; 42: 133-138Introduction: The congenital diaphragmatic hernia of the right side is the least common type of the congenital diaphragmatic defects which allows the passage of abdominal contents to the thoracic cavity, causing serious disorders on lung development. Objective: To describe the pathological features found in perinatal autopsy of a patient with Congenital Diaphragmatic Hernia of the right side at the Hospital Universitario de Santander. Case report: 35 weeks gestation neonate with prenatal diagnosis of congenital diaphragmatic hernia, who died due to acute respiratory failure. In the autopsy be found a severe pulmonary hypoplasia and in the microscopic examination, the pulmonary alveoli collapsed. Conclusion: The congenital diaphragmatic hernia of the right side is associated with high neonatal mortality and the findings in

  13. AN UNUSUAL CASE OF CONGENITAL ANOMALY OF THE HEART. UN CASO POCO COMÚN DE ANOMALÍA CONGÉNITA DEL CORAZÓN

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    Chalapathi A.V.Rao

    2011-03-01

    Full Text Available The increasing use of invasive diagnostic and interventional procedures in cardiovascular diseases makes it important that the type and frequency of vascular variations are well documented and understood. Congenital heart defects are among the most common of all birth defects. They can be thought of being common or complex lesions. In most cases of complex congenital heart defects surgical intervention is required in order to sustain life. Surgeons and Physicians need to be informed of the various forms of congenital heart diseases in order to be able to manage such conditions. We report an unusual case found on autopsy of a 28 days old male East Indian neonate, who had single atrial and single ventricular chambers of the heart, which were connected by common atrio-ventricular orifice. This congenital heart defect has to be documented. Such cases are usually incompatible with life.La creciente utilización de diagnósticos invasivos y procedimientos de intervención en enfermedades cardiovasculares han enfatizado la importancia de entender y documentar mejor el tipo y la frecuencia de las variaciones vasculares. Los defectos del corazón se encuentran entre las anomalías congénitas más comunes. Estas pueden ser simples o complejas. En la mayoría de las anomalías congénitas del corazón se requiere intervención quirúrgica para garantizar la vida. Los médicos y cirujanos deben ser educados sobre las distintas formas de enfermedades congénitas del corazón para facilitarles su manejo. En este artículo reportamos un caso de un recién nacido de 28 días de raza india al cual se le detectó, durante la autopsia, una anomalía muy poco frecuente. Esta consistía en la presencia de una sola aurícula y un sólo ventrículo comunicados por un sólo orificio aurículo-ventricular. Casos como este son incom-patibles con la vida.

  14. Identificación de mutaciones puntuales del gen de la 21-hidroxilasa en pacientes afectados con hiperplasia suprarrenal congénita.

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    Dora Fonseca

    2005-06-01

    Full Text Available lntroducción. La hiperplasia suprarrenal congénita es un trastorno autosómico recesivo debido a la inadecuada secreción de cortisol. Mas del 95% de los casos de hiperplasia suprarrenal congénita son causados por defectos del gen de la 21 hidroxilasa, CYP21A2 . Las manifestaciones clínicas incluyen la forma clásica y la forma no clásica. Objetivos. Determinar la frecuencia de las mutaciones puntuales P30L, IVS2-12AIC-G, Del 8pb, I172N, cluster Ex 6, V281L, Q318X, R356W y P453S en pacientes con hiperplasia suprarrenal congénita. Materiales y métodos. Se estudiaron 58 pacientes, de los cuales, 48 fueron clásicos y 10 no clásicos. Mediante PCR alelo-especifica y ACRS (Amplified Creation Restriction Sites, se analizaron 9 mutaciones puntuales del gen CYP21A2 y se determinó la frecuencia en la población analizada. Resultados. Los alelos afectados se identificaron en el 82,8% de los cromosomas. Las mutaciones mas frecuentes fueron: IVS2-12AIC-G (26,7%, Q318X (21,5%, V281L (12,1% e I172N (12,1%. Conclusiones. Las mutaciones mas frecuentes en Colombia son similares a las de otros países del mundo, excepto para Q318X que presentó una mayor frecuencia, pero similar a la de otros países latinoamericanos. Este hallazgo y la existencia de 17,2% de alelos no identificados puede indicar diferencia entre el acervo genético de las poblaciones. En la forma clásica perdedora de sal predominaron las mutaciones Q318X e IVS2-12AIC-G; en la virilizante simple, IVS2-12AIC-G e I172N y en la no clásica , V281L, lo cual esta relacionado con el grado de actividad enzimática. En la forma no clásica, se encontraron alelos severos en el 66,7% de los casos, lo que determina el riesgo de tener hijos afectados con la forma grave virilizante simple o perdedora de sal. Los resultados reportados permiten ofrecer asesoramiento genético y diagnóstico prenatal.

  15. Tokyo elanikud pagevad linnast. Poed kaubast tühjad / Katre Pilvinski

    Index Scriptorium Estoniae

    Pilvinski, Katre

    2011-01-01

    Tokyo poole liigub radiatsioon, mitmed elanikud lahkuvad linnast. Peaminister Naoto Kani sõnul edasise radioaktiivsuse lekke võimalus kasvab ning tehakse kõik, et vältida lekke levikut. Fukushima Daiichi tuumajaama ümbrusest on inimesed evakueeritud

  16. Mobile Learning for Expanding Educational Opportunities Workshop Report (Tokyo, Japan, May 16-20, 2005)

    Science.gov (United States)

    Meleisea, Ellie, Ed.

    2005-01-01

    The International Workshop on Mobile Learning for Expanding Educational Opportunities was held 16-20 May 2005 in Tokyo, Japan. Jointly organized by the Asian Development Bank Institute (ADBI) and UNESCO, speakers came from both the private and public sector. The key objective was to highlight the benefits of m-learning; and to provide specific…

  17. Training English Listeners to Identify Pitch-Accent Patterns in Tokyo Japanese

    Science.gov (United States)

    Shport, Irina A.

    2016-01-01

    The high-variability training paradigm (multiple words, phonetic contexts, and talkers) has been successful for perceptual learning of tone contrasts. Here, it is extended to training native English listeners on Tokyo Japanese pitch-accent contrasts. Participants had no previous experience with lexically contrastive pitch patterns. They learned to…

  18. Variations of 129I in the atmospheric fallout of Tokyo, Japan: 1963-2003.

    Science.gov (United States)

    Toyama, Chiaki; Muramatsu, Yasuyuki; Uchida, Yuka; Igarashi, Yasuhito; Aoyama, Michio; Matsuzaki, Hiroyuki

    2012-11-01

    Atmospheric fallout samples collected from Tokyo between 1963 and 2003 were analyzed using accelerator mass spectrometry (AMS) in order to determine (129)I/(127)I ratios and to examine the deposition rate of (129)I and its secular variation in Tokyo. The (129)I/(127)I ratios in the atmosphere during 1963-1977 ranged from 1 × 10(-8) to 2 × 10(-8). This is roughly 4 orders of magnitude higher than pre-atomic levels, possibly due to atmospheric nuclear weapons tests. The calculated monthly atmospheric deposition rates of (129)I differed from those produced by nuclear fallout of (90)Sr and (137)Cs, indicating that the variations in (129)I deposition are not influenced exclusively by either nuclear bomb testing or by the Chernobyl accident. After 1978, high (129)I depositions (up to 0.13 mBq/m(2)/month) were observed. The (129)I depositions started to increase markedly at the latter half of the 1970s. The secular variation of the estimated annual (129)I deposition in Tokyo showed a close relationship between the annual atmospheric discharge of (129)I from the Tokai Reprocessing plant. Therefore, the atmospheric fallout collected from Tokyo after the late 1970s is influenced primary by the (129)I discharge from the Tokai Reprocessing plant. Copyright © 2012. Published by Elsevier Ltd.

  19. TG13: Updated Tokyo Guidelines for the management of acute cholangitis and cholecystitis

    NARCIS (Netherlands)

    Takada, Tadahiro; Strasberg, Steven M.; Solomkin, Joseph S.; Pitt, Henry A.; Gomi, Harumi; Yoshida, Masahiro; Mayumi, Toshihiko; Miura, Fumihiko; Gouma, Dirk J.; Garden, O. James; Büchler, Markus W.; Kiriyama, Seiki; Yokoe, Masamichi; Kimura, Yasutoshi; Tsuyuguchi, Toshio; Itoi, Takao; Gabata, Toshifumi; Higuchi, Ryota; Okamoto, Kohji; Hata, Jiro; Murata, Atsuhiko; Kusachi, Shinya; Windsor, John A.; Supe, Avinash N.; Lee, Sunggyu; Chen, Xiao-Ping; Yamashita, Yuichi; Hirata, Koichi; Inui, Kazuo; Sumiyama, Yoshinobu

    2013-01-01

    In 2007, the Tokyo Guidelines for the management of acute cholangitis and cholecystitis (TG07) were first published in the Journal of Hepato-Biliary-Pancreatic Surgery. The fundamental policy of TG07 was to achieve the objectives of TG07 through the development of consensus among specialists in this

  20. Tokyo Halloween on the Street : Japanese Dressing Up Between Bricolage and Authenticity

    NARCIS (Netherlands)

    Groot, M.H.; Takagi, Yoko

    2017-01-01

    Drawing on perspectives related to fashion and consumerist cultures on the one hand and anthropology and appropriation on the other hand, this paper addresses dressing up on the streets during the celebration of Halloween in Tokyo, Japan. By relating commercially marketed Halloween fun-dress to

  1. Japanese Projections: A Trip to Tokyo Provides a Glimpse into the Technology of Tomorrow

    Science.gov (United States)

    Thatcher, Michelle

    2005-01-01

    This article briefly describes one person's experience with the juxtaposition of ancient religion, pop culture, and high technology of Tokyo. She describes the amazing sights she saw at the Hitachi Central Research Laboratory on a tour of the company's digital projector factory and development labs.

  2. New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo guidelines

    NARCIS (Netherlands)

    Yokoe, Masamichi; Takada, Tadahiro; Strasberg, Steven M.; Solomkin, Joseph S.; Mayumi, Toshihiko; Gomi, Harumi; Pitt, Henry A.; Gouma, Dirk J.; Garden, O. James; Büchler, Markus W.; Kiriyama, Seiki; Kimura, Yasutoshi; Tsuyuguchi, Toshio; Itoi, Takao; Yoshida, Masahiro; Miura, Fumihiko; Yamashita, Yuichi; Okamoto, Kohji; Gabata, Toshifumi; Hata, Jiro; Higuchi, Ryota; Windsor, John A.; Bornman, Philippus C.; Fan, Sheung-Tat; Singh, Harijt; de Santibanes, Eduardo; Kusachi, Shinya; Murata, Atsuhiko; Chen, Xiao-Ping; Jagannath, Palepu; Lee, Sunggyu; Padbury, Robert; Chen, Miin-Fu

    2012-01-01

    Background The Tokyo Guidelines for the management of acute cholangitis and cholecystitis (TG07) were published in 2007 as the world's first guidelines for acute cholangitis and cholecystitis. The diagnostic criteria and severity assessment of acute cholecystitis have since been widely used all over

  3. JURISDICTION OVER CRIMES COMMITTED ON BOARD AIRCRAFT IN FLIGHT UNDER THE TOKYO CONVENTION 1963

    Directory of Open Access Journals (Sweden)

    Iryna Sopilko

    2016-12-01

    Full Text Available Purpose: the main aim of this paper is to clarify several issues of conflicting jurisdiction over crimes committed on board aircraft in flight. The study will examine the way in which the Tokyo Convention attempts to provide justice in the event of aviation security violations, and discuss its effectiveness in preventing such offences in the future. Methods: formal legal and case-study methods together with inductive reasoning, and comparison were used to analyse the legislation in the area of jurisdiction over crimes and other offences committed on board aircraft in flight. Results: it follows from the study that although the Tokyo Convention has contributed considerably to the establishing of clearer rules of jurisdiction over offences committed on board aircraft, considerable deficiencies of this treaty remain. The results have important implications for international policy-making. Discussion: the results of the study reveal several weaknesses of the Tokyo Convention. Firstly, it does not provide any definition or list of offences to which it applies, instead it relies on national penal laws to do so. In addition, the ‘freedom fighter exception’ and the lack of a strong enforcement mechanism may prove to impede the effective attainment of the Tokyo Convention’s main objectives – that is, to provide justice in the event of aviation security violations, and prevent such offences in the future. Therefore, further improvement in aviation security legislation is necessary to ensure that it is effective and adequate in the challenges faced today.

  4. ONR Tokyo Scientific Bulletin. Volume 4, Number 4, October-December 1979,

    Science.gov (United States)

    1979-12-01

    large local gastropod . The nuclei have a smaller rejection rate than other materials (the Japanese cultured-pearl industry uses nuclei cut from a...Congress on Modem Pain Press Center 8F., 2-2-1, Uchisaiwai-cho Control Chiyoda-ku, Tokyo 100 undecided International Conference on Hawaii, USA. Prof. T

  5. [An autochthonous outbreak of dengue type 1 in Tokyo, Japan 2014].

    Science.gov (United States)

    Seki, Naomi; Iwashita, Yuko; Moto, Ryoko; Kamiya, Nobuyuki; Kurita, Masayuki; Tahara, Narumi; Hasegawa, Michiya; Shinkai, Takayuki; Hayashi, Yukinao; Sadamasu, Kenji; Kai, Akemi; Nakajima, Yukiko; Watase, Hirotoshi; Ueda, Takashi; Maeda, Hideo; Kobayashi, Kazushi; Ishizaki, Yasue; Hiromatsu, Kyoko

    2015-01-01

    An outbreak of autochthonous dengue fever was reported in August 2014, with cases suspected mainly from Yoyogi Park in Tokyo. This is the first epidemic of dengue fever in Japan since 1945. From August to October 2014, the following measures were taken to control the outbreak: 1) risk communication and information sharing; 2) active case finding; 3) vector surveillance in affected sites; and 4) laboratory testing. We also reviewed the surveillance data as reported to the National Epidemiological Surveillance of Infectious Diseases during the 44 epidemiological weeks. results: An official dengue fever call center was set up temporarily for the general public and 3,005 calls were received. The Tokyo Metropolitan Government issued 39 press releases regarding patients and nine related to dengue virus (DENV) detection and vector control activities for the media. Confirmed autochthonous dengue fever cases were reported between the 35th and 44th epidemiological weeks. Out of 160 cases of outbreak, 108 (67.5%) confirmed cases were reported in Tokyo. The estimated illness onset dates were between August 9 and October 7, and estimated dates of infections were between August 3 and October 3, 2014. The data suggest that the infective mosquitoes had already been present in Yoyogi Park at the end of July 2014. During the weekly vector surveillance at Yoyogi Park, a total of 1,152 adult mosquitoes, of which 856 (73.3%) were Aedes mosquitoes, were collected over 11 weeks by a light trap with dry ice. DENV was detected from adult Aedes mosquito samples collected on the 2nd, 9th, and 16th of September, 2014. Serum samples from 240 suspected cases were examined at the Tokyo Metropolitan Institute of Public Health, and 78 were positive for the DENV NS1 antigen, DENV-specific IgM antibody, or DENV nucleic acid with reverse transcriptase polymerase chain reaction (RT-PCR) (NS1: 66 cases; IgM: 50 cases; PCR: 57 cases). Genetic analysis of DENV-positive serum and mosquito samples found

  6. A 35-40% Likelihood of a Highly Damaging Tokyo Earthquake in Next 30 Years

    Science.gov (United States)

    Stein, R. S.; Toda, S.; Parsons, T.; Bozkurt, S. B.

    2005-12-01

    Tokyo and its outlying cities are home to one-quarter of Japan's 127 million people. Highly destructive earthquakes struck the capital in 1703, 1855 and 1923, the last of which took 105,000 lives. Reoccurrence of any of these shocks today would cost about one trillion dollars, of which perhaps 10% is insured. Fueled by Tokyo's rich data trove but hindered by its complexity, we carried out a new hazard assessment. We used the prehistoric record of great earthquakes preserved in uplifted marine terraces and tsunami deposits (17 M~8 shocks in the past 7,000 years), historical shaking (10,000 intensity observations in the past 400 years), the dense modern seismic network (300,000 earthquakes in the past 30 years), and the world's best geodetic array (150 GPS vectors spanning the past 10 years). We propose that a dislodged block of the Pacific plate is jammed between the Pacific, Philippine Sea and Eurasian plates beneath Tokyo, and controls much of Tokyo's seismic behavior for M≤7.5 shocks, including the damaging 1855 M~7.3 Ansei-Edo shock. On the basis of frequency-magnitude curves, earthquakes similar to the Ansei-Edo event should be quite frequent (25-35% likelihood in an average 30-yr period), and so such events dominate the combined probabilities. In contrast, our renewal model for the great 1703 and 1923 type plate boundary shocks yields a ~1% probability for the next 30 yr, with a time-averaged 30-yr probability of ~8%. The resulting net likelihood for severe shaking in Tokyo, Kawasaki, and Yokohama for the next 30 years is 25%-40%, but how can it be validated? The long historical record in Kanto affords a rare opportunity to calculate the probability of shaking in an alternative manner, based almost exclusively on intensity observations. This approach permits robust estimates for the spatial distribution of shaking, even for sites with few observations. The resulting probability of severe shaking over an average 30-yr period is ~35% in the Tokyo, Kawasaki

  7. Cardiopatía congénita del adulto: tratamiento percutáneo de un caso complejo Adult congenital cardiopathy: percutaneous treatment of a complex case

    OpenAIRE

    Alberto Suárez N; Andrés Carvajal; Sabas Bustillo; Luis E Lobo; Alberto Mayorga

    2008-01-01

    La cardiopatía congénita del adulto, es una entidad clínica de difícil diagnóstico y tratamiento. Desde 1982, la terapia endovascular cambió su enfoque de manera radical (1) y en los últimos años el diseño de nuevos dispositivos y mejores catéteres de balón, facilitó la implementación de la terapéutica para mayor número de pacientes (2). Es el tratamiento de elección para entidades como estenosis valvular pulmonar (3), comunicación ínter-auricular (4) y ductus arterioso persistente (5). Se pr...

  8. Implante de stents en ramas de arterias pulmonares en cardiopatías congénitas: experiencia multicéntrica de 10 años

    Directory of Open Access Journals (Sweden)

    Alejandro Peirone

    2016-01-01

    Full Text Available Introducción: La angioplastia con implante de stent se considera el tratamiento de elección para la mayoría de los casos de estenosis congénita o adquirida posquirúrgica de ramas de arterias pulmonares en pacientes portadores de cardiopatías congénitas. Sin embargo, aún persisten dudas sobre la efectividad clínica y la incidencia de complicaciones de esta técnica que necesitan ser esclarecidas. Material y métodos: Estudio multicéntrico descriptivo, retrospectivo, observacional. Los procedimientos se realizaron desde enero de 2005 hasta abril de 2015. Un total 25 pacientes fueron sometidos a angioplastia con implante de stent en ramas de arterias pulmonares, los cuales fueron seguidos evolutivamente en su estado clínico y por diferentes métodos de imágenes. Se definió buena efectividad clínica al mejoramiento clínico sintomático y/o anatómico persistente del paciente intervenido. Resultados: La cohorte de 25 pacientes tenía una edad promedio de 9,48 años (2 meses-34 años, un peso promedio de 27,54 kg (3-104 y el 44% era de sexo femenino. Las cardiopatías congénitas de base intervenidas fueron en su mayoría tetralogía de Fallot y sus variantes, seguida por corazones con fisiología univentricular poscirugías de Glenn bidireccional y/o de FontanKreutzer. La presión sistólica del ventrículo derecho y de la arteria pulmonar disminuyeron significativamente posintervención (de 68,35 mm Hg a 45,8 mm Hg y de 47,4 mm Hg a 32,08 mm Hg, respectivamente (p < 0,0001. El diámetro mínimo de la lesión a tratar se incrementó significativamente posprocedimiento (de 3,98 mm a 9,82 mm; p < 0,0001. La incidencia de complicaciones fue del 8% (2 pacientes y se registró buena efectividad clínica en 22 pacientes (88%. Conclusiones: La angioplastia con colocación de stent en las ramas de arterias pulmonares resultó una técnica segura y eficaz, aunque desafiante, con una marcada mejoría clínica y anatómica de las lesiones

  9. Maternal and congenital syphilis in rural Haiti Sífilis materna y congénita en zonas rurales de Haití

    Directory of Open Access Journals (Sweden)

    Chaylah J. Lomotey

    2009-09-01

    Full Text Available OBJECTIVES: A study was conducted to assess the prevalence of maternal syphilis and estimate the rate of congenital syphilis in five rural villages surrounding Jeremie, Haiti. METHODS: This research was a retrospective observational study. Data were extracted from the Haitian Health Foundation's public health database and verified through original clinical paper records, death certificates, midwife reports, and discussions with community health workers. Data were analyzed by chi-square analysis, bivariate correlations, and two-tailed t-test for independent samples. RESULTS: Of the 410 women tested for syphilis, 31 (7.6% were sero-reactive. Average gestation at time of testing was 25 weeks, which correlated with entry into prenatal care at an average of 23 weeks. Women who tested positive during pregnancy were more likely to have had a negative pregnancy outcome than those who did not (chi square = 16.4; P OBJETIVOS: Evaluar la prevalencia de sífilis materna y estimar la tasa de sífilis congénita en cinco poblaciones rurales cercanas a Jeremie, Haití. MÉTODOS: Estudio observacional retrospectivo a partir de datos extraídos de la base de datos de salud pública de la Fundación Haitiana de Salud y verificada con los registros clínicos originales en papel, los certificados de defunción, los informes de las parteras y discusiones con los trabajadores comunitarios de salud. Los datos se analizaron mediante la prueba de la ji al cuadrado, correlaciones bifactoriales y la prueba de la t de dos colas para muestras independientes. RESULTADOS: De las 410 mujeres sometidas a la prueba de sífilis, 31 (7,6% resultaron seropositivas. La edad gestacional promedio al momento de la prueba fue de 25 semanas, lo que se correlacionó con la edad gestacional de entrada a la atención prenatal (23 semanas. Las mujeres que resultaron seropositivas durante el embarazo presentaron mayor probabilidad de tener un desenlace negativo de su embarazo que las mujeres

  10. Bhandari, Dr Nita

    Indian Academy of Sciences (India)

    Specialization: Nutrition-Infection Interaction, Child Health, Nutritional Interventions, Clinical Evaluation of Vaccine Address: President & Director, Centre for Health R&D Society for Applied Studies, 45, Kalu Sarai, New Delhi 110 016, U.T.. Contact: Office: (011) 4604 3751-55. Residence: (011) 4174 8476. Mobile: 98991 ...

  11. Desprendimiento seroso macular asociado a foseta papilar congénita y coloboma de papila: ¿Qué opciones terapéuticas tenemos?

    Directory of Open Access Journals (Sweden)

    Caridad Chiang Rodríguez

    Full Text Available La foseta papilar es una rara anomalía congénita que forma parte del espectro de las anormalidades congénitas del disco óptico. Se trata de invaginaciones intrapapilares que suelen localizarse en el margen del disco óptico. La mayoría se localiza a nivel temporal; en torno al 20 % son de localización central seguidas por las fosetas superiores, inferiores o nasales. La bilateralidad se estima en un 10-15 % y su incidencia se ha establecido en torno al 0,19 %. Suelen ser asintomáticas, aunque en aproximadamente el 50 % de los casos se produce afectación macular por el paso de fluido procedente desde la foseta papilar hacia las diferentes capas retinianas, lo que afecta secundariamente la agudeza visual y es, por tanto, el motivo de consulta. Hasta el momento se han descrito múltiples alternativas terapéuticas para el tratamiento de los desprendimientos de retina serosos asociados a foseta de papila, pero ninguna de estas alternativas se ha impuesto sobre el resto. El tratamiento de esta enfermedad consiste en cerrar la comunicación entre la foseta y el espacio subretiniano con diversas opciones terapéuticas como: la fotocoagulación láser, la neumoretinopexia, la indentación escleral posterior, la fenestración del nervio óptico, la vitrectomía o alguna combinación de las anteriores. La actual revisión bibliográfica se propone profundizar en el tema, sobre la base de pacientes en consulta con dicha afección retiniana.

  12. Situs Inversus Totalis y Cardiopatía congénita: Diagnóstico casual en un lactante con neumonía

    Directory of Open Access Journals (Sweden)

    Hebel Oziel Urquia Osorio

    2012-02-01

    Full Text Available El Situs Inversus Totalis es una rara entidad que se caracteriza por la imagen en espejo de las vísceras torácicas y abdominales con respecto al plano sagital, cuya prevalencia se estima de 1-2/10,000 nacidos vivos, de los cuales solo el 1-10% presentan malformaciones cardiovasculares congénitas asociadas. Presentamos el caso de un lactante de sexo masculino de 11 meses de edad, que fue atendido en el ¨Hospital Materno Infantil¨ ubicado en la ciudad de Tegucigalpa, Honduras, por presentar tos seca, cianotizante no emetizante de 1 mes de evolución, exacerbada en los últimos 4 días y acompañada de dificultad respiratoria con periodos de apnea, fiebre subjetivamente alta, tiraje subcostal, taquipnea y crépitos basales bilaterales. La realización de una radiografía de tórax reveló: dextrocardia, bazo y cámara gástrica lateralizados hacia la derecha e hígado hacia la izquierda. Se decide realizar una ecocardiografía y un ultrasonido abdominal para verificar el hallazgo, reportando: situs inversus, dextrocardia, agenesia de la vena cava inferior, defecto interventricular de entrada (tipo canal, ductos arterioso, vasos transpuestos, bazo en cuadrante superior derecho e hígado localizado en cuadrante superior izquierdo. El diagnostico de esta condición pasa desapercibido en la mayoría de los casos, por esta razón debemos incentivar la práctica de un examen físico minucioso, evitando así la dependencia de los hallazgos fortuitos e incidentales. Palabras Claves: Situs Inversus, Cardiopatía Congénita, Dextrocardia.

  13. Presentación de un caso de hemidisplasia congénita con ictiosis eritrodérmica Report of a congenital hemidysplasia with erythrodermic ichthyosis

    Directory of Open Access Journals (Sweden)

    Andrés A. Morilla Guzmán

    2008-09-01

    Full Text Available La hemidisplasia congénita con ictiosis y defectos de las extremidades es una enfermedad infrecuente, hereditaria, monogénica, que se transmite como un rasgo dominante ligado al cromosoma X. Se presenta el caso de una paciente con este diagnóstico clínico neonatal, que presentaba eritrodermia ictiosiforme en el hemicuerpo derecho, acompañada de hipomelia del miembro superior e inferior derechos, defectos óseos en miembros afectados y columna vertebral, agenesia renal unilateral, cardiopatía congénita de tipo comunicación interventricular conoventricular y arteria umbilical única. Se realizaron las interconsultas necesarias, estudios sonográficos y radiológicos para completar el diagnóstico y se ofreció asesoramiento genético y seguimiento del caso según las complicaciones reportadas en la literatura médica y los hallazgos clínicos de la paciente.Congenital hemidysplasia with icthyosis and limb defects is a hereditary, monogenic and infrequent disease transmitted as a dominant trait linked to the X chromosome. The case of a female patient with this neonatal clinical diagnosis showing ichthyosiform erythroderma on the right hemibody, accompanied with hypomelia of the right upper and lower limbs, bone defects in the affected limbs and spinal column, unilateral renal agenesia, congenital heart disease with inter- and conoventricular communication, and a unique umbilical artery was reported. The necessary inter-consultations were arranged and sonographic and radiological studies were conducted to complete the diagnosis. Genetic counselling was given and the case was followed up according to the complications reported in medical literature, and to the clinical findings of the patient.

  14. Adherencia de los profesionales al protocolo de manejo y red de apoyo familiar de sífilis gestacional y congénita

    Directory of Open Access Journals (Sweden)

    Luz Myriam Tobón-Borrero

    2014-12-01

    Full Text Available Objetivo: Determinar la adherencia de los profesionales médicos y de enfermería al protocolo de sífilis congénita y gestacional implementado por el Ministerio de la Protección Social. Materiales y Métodos: Estudio descriptivo longitudinal con una población de 215 gestantes y una muestra de 11 gestantes diagnosticadas con sífilis gestacional en 10 municipios de un departamento en Colombia entre febrero y abril de 2013. Se utilizaron como instrumentos el Familiograma, Faces III (Olson, Lista de chequeo protocolo. Medidas de tendencia central. Participación voluntaria bajo consentimiento informado. Resultados: la media poblacional es de 20 años, baja escolaridad, amas de casa, en unión libre, todas afiliadas a seguridad social. El 60% corresponde a familias nucleares, faces III: 50% familias equilibradas, 30% moderadas y 20% extremas. Protocolo: Una gestante no tuvo control prenatal, el 54,5% no registran factores de riesgo, 60,3% diagnosticadas en tercer trimestre, 36,3% de recién nacidos con sífilis congénita, no se registra seguimiento serológico, no hay registro educativo a la paciente ni a la pareja, no hay valoración de genitales ni piel en examen físico de las gestantes, atención a RN incompleta, tratamiento suministrado adecuado. Conclusiones: Predominio de las familias nucleares y equilibradas, con capacidad de aprender de las crisis. No hay adherencia total al protocolo, no hay seguimiento por parte de los profesionales que brindan atención y cuidado a la usuaria. Se evidencia falta de educación continua en el tema al profesional de enfermería como líder del proceso en la región.

  15. [Analyses of the activities of home care supporting clinics in Tokyo from the standpoint of place of death].

    Science.gov (United States)

    Tsukada, Chihiro; Hanabusa, Hiroo; Akiyama, Akiko

    2013-12-01

    We examined the activities of home care supporting clinics (HCSC) in Tokyo, Japan, from the standpoint of the place of death. The number of HCSCs in Tokyo was 1,246 in 2010. Fifteen HCSCs cared for > or = 50 patients who died at home in a year. In contrast, the 19 HCSCs in the top 10 percentile for the number of patients (> or = 176) did not have any patients who died at home. Their patients died at hospitals or facilities. These results suggest that the activities of HCSCs in Tokyo are diverse.

  16. Comparison of tropospheric NO2 observations by GOME and ground stations over Tokyo, Japan

    Science.gov (United States)

    Noguchi, K.; Itoh, H.; Shibasaki, T.; Hayashida, S.; Uno, I.; Ohara, T.; Richter, A.; Burrows, J. P.

    2009-04-01

    Nitrogen oxides (NOx = NO + NO2) are anthropogenically emitted as a form of NO in the high-temperature burning processes of fossil fuels mainly in energy generations and vehicles. Because NOx is a precursor of ozone, which is composed of a so-called photochemical smog, and is a health-hazard matter, the monitoring of NO2 is important to control air quality. The satellite observation is one of the most suitable methods for the monitoring of air pollution because satellite observations can obtain a global distribution of the pollutants. However, the observation of tropospheric gases by satellites still includes technically challenging problems, and the field is developing. To test whether satellite observations could successfully detect the behavior of tropospheric NO2, we compared satellite and ground-based observations of tropospheric NO2 over the Tokyo region. The satellite data were tropospheric NO2 vertical column density (VCD) derived from Global Ozone Monitoring Experiment (GOME) spectrometer measurements (hereafter GOME-NO2) [Richter et al., 2005], and the ground-based data were surface NO2 volume mixing ratio (VMR) observed by the network of air-quality monitoring stations in Tokyo. The analysis was performed for the data from January 1996 to June 2003. We found a strong correlation between GOME-NO2 and the surface VMR. They showed a similar seasonal variation with a maximum in winter and a minimum in summer. The result suggested that GOME was observing the behavior of NO2 near the surface in the Tokyo region. A more rigorous comparison was conducted by scaling the surface NO2 VMR to the tropospheric VCD with vertical NO2 VMR profiles. The NO2 profiles were calculated by using the chemical transport model CMAQ/REAS [Uno et al., 2007; Ohara et al., 2007]. This second comparison indicated that the GOME observations represent the behavior of NO2 more closely at the relatively unpolluted ground stations than at the highly polluted ground stations of the air

  17. Validación de la escala Impact on family Scale (IOFS) en el contexto de un grupo de familias colombianas con un hijo afectado por malformaciones congénitas mayores

    OpenAIRE

    Suarez Obando, Fernando

    2010-01-01

    Objetivo: validar la escala Impact on Family Scale (IOFS) en el contexto de un grupo de familias colombianas con un hijo afectado por malformaciones congénitas mayores. Diseño: validación lingüística y psicométrica de la escala. Lugar: Consulta de Genética Clínica de varios hospitales de Bogotá. Población: familias con un hijo afectado por malformaciones congénitas mayores. Mediciones: validación lingüística basada en el proceso de traducción - retrotraducción. Validación psicométrica de cont...

  18. Cardiopatías congénitas en adultos intervenidos en el Servicio Murciano de Salud en los últimos 10 años : su incidencia y resultados a corto, medio y largo plazo

    OpenAIRE

    Roldán Ramos, Sara

    2012-01-01

    Introducción: Hasta hace poco únicamente pacientes con cardiopatías «muy simples» podían llegar a adultos por su natural tendencia a sobrevivir. Actualmente la población de adultos con cardiopatías congénitas está en rápido crecimiento gracias a la cirugía cardíaca, y desconocemos su evolución. Objetivos: Estudio de los adultos con cardiopatías congénitas intervenidos quirúrgicamente en los últimos diez años en el Servicio Murciano de Salud. Métodos: Análisis estadístico e interpretac...

  19. Seasonal variations and sources of sedimentary organic carbon in Tokyo Bay.

    Science.gov (United States)

    Kubo, Atsushi; Kanda, Jota

    2017-01-30

    Total organic carbon (TOC), total nitrogen (TN) contents, their stable C and N isotope ratio (δ 13 C and δ 15 N), and chlorophyll a ([Chl a] sed ) of surface sediments were investigated monthly to identify the seasonal variations and sources of organic matter in Tokyo Bay. The sedimentary TOC (TOC sed ) and TN (TN sed ) contents, and the sedimentary δ 13 C and δ 15 N (δ 13 C sed and δ 15 N sed ) values were higher in summer than other seasons. The seasonal variations were controlled by high primary production in the water column and hypoxic water in the bottom water during summer. The fraction of terrestrial and marine derived organic matter was estimated by Bayesian mixing model using stable isotope data and TOC/TN ratio. Surface sediments in Tokyo Bay are dominated by marine derived organic matter, which accounts for about 69±5% of TOC sed . Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Long term change of diurnal cycle in surface air temperature over Tokyo metropolitan area

    Science.gov (United States)

    Hara, M.; Shimada, T.

    2017-12-01

    Tokyo Metropolitan area (i.e. southern part of Kanto district) is known for one of the hottest areas in summer in Japan. Especially in Saitama prefecture (north of Tokyo), the daily maximum surface air temperature (SAT) at screen height sometimes reached in 40 C. In the last decade, the summer heat environment in Japan is getting worse, and the number of emergency transportations due to heat stroke is rapidly increasing. In this study, we evaluate regional climate change due to some factors, such as land use / land cover changes. To evaluate the regional climate change, we performed analysis of observed data and a series of past climate simulations using the Weather Research and Forecasting (WRF) model with high horizontal resolution, including an urban canopy sub-model.

  1. Prevalence and contamination levels of listeria monocytogenes in ready-to-eat foods in Tokyo, Japan.

    Science.gov (United States)

    Shimojima, Yukako; Ida, Miki; Nakama, Akiko; Nishino, Yukari; Fukui, Rie; Kuroda, Sumiyo; Hirai, Akihiko; Kai, Akemi; Sadamasu, Kenji

    2016-08-01

    We surveyed prevalence and contamination levels of Listeria monocytogenes in ready-to-eat foods between 2000 and 2012 in Tokyo. L. monocytogenes was isolated from 52 (1.7%) out of 2,980 samples. Comparing the prevalence in the study period, 2.2% were positive in the former period (2000-2005) and 1.2% in the latter (2006-2012). Using the most probable number (MPN) technique, 32 samples were contaminated with fewer than 0.3 L. monocytogenes/g, 10 samples with 0.3-1.0/g and 4 samples with more than 1.0/g (the maximum was 2.3/g). The most common serovar was 1/2a, followed by 1/2b, 4b and 1/2c. We revealed that ready-to-eat foods in Tokyo were contaminated with L. monocytogenes, although the contamination levels were low.

  2. Design and study of far infrared free electron laser at Tokyo University of Science

    CERN Document Server

    Koike, H; Yokoyama, M; Oda, F; Kawai, M; Kuroda, H; Nakai, K; Toyoda, K

    2002-01-01

    The FIR-FEL project group, collaboration of Tokyo University of Science and Kawasaki Heavy Industry, Ltd. (KHI), has completed the design of an S-band linac based FIR-FEL device at a spectral range between 300 and 1000 micrometers in 2000. And the FEL device has already been installed in the IR FEL Center at Tokyo University of Science in April 2002. Our optical resonator is composed of a waveguide with a gap of 4.5 mm and two cylindrical mirrors positioned among the waveguide surfaces in order to improve a slippage problem and diffraction losses. The waveguide makes a slippage length reduce and makes a lasing at the spectral range easier. In this paper, the design and the fabrication of the FIR-FEL device, RF components, linac, optical resonator, and beam transport line are described. (author)

  3. Social, not physical, infrastructure: the critical role of civil society after the 1923 Tokyo earthquake.

    Science.gov (United States)

    Aldrich, Daniel P

    2012-07-01

    Despite the tremendous destruction wrought by catastrophes, social science holds few quantitative assessments of explanations for the rate of recovery. This article illuminates four factors-damage, population density, human capital, and economic capital-that are thought to explain the variation in the pace of population recovery following disaster; it also explores the popular but relatively untested factor of social capital. Using time-series, cross-sectional models and propensity score matching, it tests these approaches using new data from the rebuilding of 39 neighbourhoods in Tokyo after its 1923 earthquake. Social capital, more than earthquake damage, population density, human capital, or economic capital, best predicts population recovery in post-earthquake Tokyo. These findings suggest new approaches for research on social capital and disasters as well as public policy avenues for handling catastrophes. © 2012 The Author(s). Journal compilation © Overseas Development Institute, 2012.

  4. Highly charged ion beams from the Tokyo EBIT for applications to nano-science and -technology

    International Nuclear Information System (INIS)

    Tona, Masahide; Takahashi, Satoshi

    2004-01-01

    We report present status of a beam line for transportation of highly charged ions (HCIs) extracted from the Tokyo EBIT. We have produced continuous beams of 2.5 x 10 5 cps for Xe 44+ through a 1 mm aperture. With slightly high energy operation (electron beam energy: 78 keV) of the Tokyo EBIT, we have also obtained 10 3 ions/pulse for Ta 70+ HCIs extracted by a pulse mode (trapping time: 3 sec). We are going to apply such HCI beams to nano-processes on solid surfaces by utilizing some useful characteristics of the HCI-interactions. Future perspective of HCI-based nano-science and -technology is presented

  5. The Tokyo subway sarin attack: disaster management, Part 3: National and international responses.

    Science.gov (United States)

    Okumura, T; Suzuki, K; Fukuda, A; Kohama, A; Takasu, N; Ishimatsu, S; Hinohara, S

    1998-06-01

    The authors report the national and international responses to the disaster produced by the Tokyo subway sarin attack. From a worldwide historical perspective, there had never been such a large-scale disaster caused by nerve gas during peacetime. Therefore, this event should be studied from various viewpoints in cooperation with members of the international community. To this end, the Japanese government should help coordinate a large-scale and detailed investigation of the Tokyo subway sarin attack, including the long-term effects of sarin. The authors also recommend that the Japanese Self Defense Forces should be used more effectively in large-scale disasters. The system of direct control of disaster management by the Japanese government could be useful in a large-scale disaster.

  6. Inventory of the Heteroptera (Insecta: Hemiptera) in Komaba Campus of the University of Tokyo, a highly urbanized area in Japan

    Science.gov (United States)

    Saito, Masayuki U.; Kishimoto-Yamada, Keiko; Kato, Toshihide; Kurashima, Osamu; Ito, Motomi

    2015-01-01

    Abstract Background The Heteroptera, or true bugs, forms one of the major insect groups with respect to the very diverse habitat preferences, including both aquatic and terrestrial species, as well as a variety of feeding types. The first comprehensive inventory of the Heteroptera at Komaba Campus of the University of Tokyo, or an urban green space in the center of the Tokyo Metropolis, Japan, was conducted. New information A total of 115 species in 29 families of the suborder Heteroptera were identified. The area had a high species richness compared with other urbanized and suburbanized localities in Tokyo. The campus is found to show a substantial difference in heteropteran species compositions, despite being close to the other localities surrounded by highly urbanized zones in central Tokyo. PMID:25941455

  7. 77 FR 56909 - Culturally Significant Objects Imported for Exhibition Determinations: “Tokyo 1955-70: A New...

    Science.gov (United States)

    2012-09-14

    ... the Museum of Modern Art, New York, NY, from on or about November 18, 2012, until on or about February... ``Tokyo 1955-70: A New Avant-Garde,'' imported from abroad for temporary exhibition within the United...

  8. Antibacterial Therapy of Acute Cholecystitis and Cholangitis (According to Tokyo Guidelines2013

    Directory of Open Access Journals (Sweden)

    Yu.M. Stepanov

    2015-04-01

    Antibiotics should be used wisely in antimicrobial therapy in each institution, region and country. The recent global spread of antibiotic resistance gives us a warning in the modern practice. Tokyo Guidelines 2013 provide practical guidance for physicians and surgeons involved in the treatment of community-acquired and hospital acute biliary infection. Much remains uncertain in this view. Continuous monitoring of local resistance to antibiotics and further studies in acute cholecystitis and cholangitis should be justified.

  9. Dengue Virus Infection inAedes albopictusduring the 2014 Autochthonous Dengue Outbreak in Tokyo Metropolis, Japan.

    Science.gov (United States)

    Kobayashi, Daisuke; Murota, Katsunori; Fujita, Ryosuke; Itokawa, Kentaro; Kotaki, Akira; Moi, Meng Ling; Ejiri, Hiroko; Maekawa, Yoshihide; Ogawa, Kohei; Tsuda, Yoshio; Sasaki, Toshinori; Kobayashi, Mutsuo; Takasaki, Tomohiko; Isawa, Haruhiko; Sawabe, Kyoko

    2018-03-19

    In 2014 in Japan, 162 autochthonous dengue cases were reported for the first time in nearly 70 years. Here, we report the results of the detection and isolation of dengue virus (DENV) from mosquitoes collected in Tokyo Metropolis in 2014 and 2015. The phylogenetic relationship among DENV isolates from mosquitoes and from patients based on both the entire envelope gene and whole coding sequences was evaluated. Herein, 2,298 female and 956 male Aedes albopictus mosquitoes were collected at six suspected locations of DENV infection in Tokyo Metropolis from August to October in 2014 and grouped into 124 and 35 pools, respectively, for viral genome detection and DENV isolation. Dengue virus RNA was detected using reverse transcription polymerase chain reaction and TaqMan assays from 49 female pools; 16 isolates were obtained using C6/36 and Vero cells. High minimum infection rates (11.2-66.7) persisted until mid-September. All DENV isolates belonged to the genotype I in serotype 1 (DENV-1), and its sequences demonstrated > 99% homology to the sequence of the DENV isolated from a patient in the vicinity of Tokyo Metropolis in 2014. Therefore, Ae. albopictus was a major DENV vector, and a single DENV-1 strain circulated in Tokyo Metropolis in 2014. Dengue virus was not detected from male mosquitoes in 2014 and wild larvae in April 2015. Thus, the possibility of both vertical transmission and overwintering of DENV was extremely low, even in dengue-epidemic areas. This study reports the first entomological information on a dengue outbreak in a temperate region, where no Aedes aegypti mosquitoes are distributed.

  10. ONR Tokyo Scientific Bulletin. Volume 5, Number 1, January-March 1980,

    Science.gov (United States)

    1980-03-01

    postage stamps and a children’s poster contest, for which SCOPE provided prize money. SCOPE is now organizing a seminar on ecotoxicological problems in... Pharmaceutical Association, cal Sciences of the Federation of 2-12-15-701, Shibuya, Shibuya-ku, Asian Pharmaceutical Associa- Tokyo 150 tions Headquarters: The...Federation of Asian Pharmaceutical Associations (FAPA), Hizon Bldg., 29 Quezon Bd., Quezon City, Philippines August 25-29 12th Australian Spectroscopy

  11. The 2011 measles outbreak in Tokyo. An analysis of surveillance data.

    Science.gov (United States)

    Nadaoka, Yoko; Hayata, Noriko; Sugishita, Yoshiyuki; Kajiwara, Toshiko; Watanabe, Yu; Yoshida, Michihiko; Hasegawa, Michiya; Hayashi, Yukinao; Ochi, Masayo; Kai, Akemi; Sumitomo, Masami

    2014-01-01

    The study was conducted with the intention of establishing a strategy to eliminate measles on the basis of an analysis of the epidemiological profile of measles cases reported in Tokyo during the year 2011. We investigated measles cases reported to the Tokyo Metropolitan Government in 2011, recorded as part of the National Epidemiological Surveillance of Infectious Diseases. Factors analyzed included age, vaccination status for each patient, cases for which records were discarded after laboratory confirmation, genotype of the measles virus and relationships between dates of specimen collection and results of polymerase chain reaction (PCR) and IgM antibody tests. A total of 178 measles cases were reported in Tokyo during 2011, and the majority of cases (128, 71.9%) were reported during the peak period from epiweeks 13 to 24. The largest age group reported was one to four years of age (40, 22.5%) followed by groups of 20-29 and 30-39 years of age (both 34, 19.1%). Most cases were sporadic, with only six outbreaks occurring. Even then, the numbers of cases for each outbreak was less than five. More than half of the patients in all age groups, except for the 1-4-year-old group, had not been vaccinated or did not have a record of vaccination. Genotypes D4 and D9 of measles virus were detected in most cases. However, genotype D5, which had been circulating in Japan before 2008, was not detected. Imported viruses were the cause of measles cases reported in Tokyo during 2011. The disease control was better than that in 2007 and 2008 because of the swift and appropriate responses to the occurrences. It is also possible that there has been an increase in the proportion of people with immunity to measles. Increasing the rate of immunization, performing effective surveillance, and confirming suspicious measles cases by using molecular methods are important for achieving the elimination of measles.

  12. The Earthquake Proof ‘Tokyo Sky-Tree‘- Bringing New Possibilities for Modern Architecture

    OpenAIRE

    T. Sai Shiva Prasad,; P. Pranoosha

    2015-01-01

    The pagodas have always fascinated the people who see them. Not only are they interesting, but they also represent the essence of science and architecture which was used in the olden days. Thus, bringing new possibilities for modern architecture. The world’s tallest tower and Japan’s biggest new landmark, The Tokyo Sky-tree is one among them which remains unaffected when the earthquake strikes. In our paper, we are going to review the construction technologies used in building thi...

  13. A Study of the Tuition of Middle Schools in Prwear Tokyo Prefecture

    OpenAIRE

    Karasuda, Naoya

    2002-01-01

    The purpose of this paper is to clarifying the tuition in middle schools at the prewar Tokyo prefecture. The tuition differed between the public schools and the private schools. In the 1890s, most expenses required for management of middle schools was provided with tuition in both private amd public schools. At this time, the tuition of public schools was higher than the private schools. After 1900 tuition of public schools became cheaper than private schools. As expenses of public schools, i...

  14. ONR Tokyo Scientific Bulletin. Volume 6, Number 2, April-June 1981,

    Science.gov (United States)

    1981-06-01

    welding Behavior of carbon in surface segregation and Kazuyoshi N ii oxidation in heat resisting alloys Corrosion prevention of aluminum and steel by...Hiroyuki Hiroyasu (Diesel Engines) Department of Mechanical Engineering Hiroshima University 3-8-2, Senda Machi, Hiroshima 730 62 Kazuo Hishida... Senda -machi, Hiroshima-shi 730 Senichi Masuda (Electrostatic Precipitation) Department of Electrical Engineering University of Tokyo 7-3- I, Hongo

  15. EMERGING IP MARKETS: THE TOKYO GRAIN EXCHANGE NON-GMO SOYBEAN CONTRACT

    OpenAIRE

    Parcell, Joseph L.

    2002-01-01

    This research provides an overview of the development of the Tokyo Grain Exchange non-GMO soybean contract as an identity preserved futures contract. The development of this contract is unique, relative to the development of other new futures contracts, in that a mature conventional soybean futures contract exists. Particular attention was given to established necessary conditions for the development of a new futures contract. In evaluating these conditions it was determined that since incept...

  16. ONR Tokyo Scientific Bulletin. Volume 5, Number 4, October-December 1980

    Science.gov (United States)

    1980-12-01

    ACCESSION NO. 3 RECIPIENT’S CATALOG NUMBER ONR/T VOL 5, NO 4 7M-I f 6 4 TITE (,S~SIII.I5 TYPE OF REPORT A PERIOD COVERED (4 NR TOKYO CIENTIFIC BULLETIN...cobalt above that obtainable even with SmCos. Recent Japanese and Swiss work has indi-ated that energy product, (BII)mu. in excess of 30 MGOe can be

  17. Protocolo de atención a niños y adolescentes con cardiopatía congénita en odontopediatría. Revision bibliográfica

    Directory of Open Access Journals (Sweden)

    Juan Manuel de Jesús Cortes de la Torre

    2015-07-01

    Full Text Available Introducción. Las cardiopatías congénitas son las malformaciones más habituales en el desarrollo de los niños los cuales, además, son susceptibles a desarrollar infecciones sistémicas microbianas secundarias a infecciones locales polimicrobianas como consecuencia de procedimientos dentales invasivos o toman fármacos, por ejemplo anti-coagulantes, antiarrítmicos, u otros, que pueden interferir con el manejo odontológico. Objetivo. Proponer un protocolo de manejo odontológico que permita detectar las cardiopatías congénitas o ya identificadas tener un abordaje dental que disminuya el riesgo de sepsis o endocarditis para el paciente pediátrico. Método. Revisión de la literatura a través de artículos indexados en Cochrane, Medline, Lilacs, EMBASE, Amedeo y SciELO, enfatizando los últimos cinco años, en los idiomas: francés, italiano, portugués, inglés y español. Resultados. Se presenta un protocolo odonde abordaje odontológico que disminuya los factores de riesgo ante la presencia de cardiopatías congénitas. Conclusión. Ya que existe una au-sencia de información sobre la relación de las cardiopatías congénitas y la odontología infantil, por ello la importancia de contar con un protocolo para el tratamiento de pacientes pediátricos mejorando su atención, pronóstico, calidad de vida y disminuyendo los factores de riesgo ante procedimientos dentales invasivos.

  18. Taquicardia por reentrada nodal recurrente en paciente con transposición congénita corregida de grandes vasos. Utilización de mapeo no fluoroscópico

    OpenAIRE

    Aristizábal,Julián; Uribe,William; Duque,Mauricio; Marín,Jorge; Medina,Eduardo; Velásquez,Jorge; Femenía,Francisco; Baranchuk,Adrían

    2013-01-01

    La complejidad anatómica y la variabilidad en el sistema de conducción en la transposición congénita corregida de los grandes vasos plantean intervenciones con el uso de recursos tecnológicos que faciliten un desenlace favorable. Describimos un caso de ablación de taquicardia por reentrada intranodal en donde el mapeo no fluoroscópico facilitó una intervención compleja.

  19. Increase in Primary and Secondary Syphilis Notifications in Men in Tokyo, 2007-2013.

    Science.gov (United States)

    Sugishita, Yoshiyuki; Yamagishi, Takuya; Arima, Yuzo; Hori, Narumi; Seki, Naomi

    2016-01-01

    The number of notified syphilis cases in Tokyo has more than doubled in recent years. The number of reported primary and secondary syphilis cases increased from 108 cases (0.8 per 100,000 population) in 2007 to 245 cases in 2013 (1.9 per 100,000 population). During this period, the majority of cases was male (905/1,024), and the recent increase among primary and secondary syphilis cases was attributed to the increase among males (90/108 [83%] cases in 2007 to 218/245 [89%] cases in 2013); men aged 20-49 years contributed most to the increase, with those aged 30-34 years having the highest notification rate in 2013. Male-to-male transmission was the primary route of infection reported, and men who have sex with men (MSM) accounted for nearly 80% of male cases in 2013. Syphilis appears to be reemerging in Tokyo, and reducing the risk of acquiring syphilis among MSM aged 20-49 years should be a public health priority in Tokyo.

  20. Ongoing rubella outbreak among adults in Tokyo, Japan, June 2012 to April 2013

    Directory of Open Access Journals (Sweden)

    Yoshiyuki Sugishita

    2013-08-01

    Full Text Available Introduction: A large rubella outbreak has been occurring in Tokyo, Japan since June 2012. Rubella vaccination, introduced in Japan in 1976, has targeted different age groups, resulting in a large proportion of the current population being unvaccinated. Methods: Rubella cases reported in Tokyo from 2 January 2012 to 21 April 2013 were analysed. A clinical case had generalized maculopapular rash, fever and lymphadenopathy; a laboratory-confirmed case was a clinical case with a positive serology or polymerase chain reaction test for rubella. A descriptive analysis of cases by age, sex, vaccination history and other epidemiological information was conducted. Results: A total of 2382 cases were reported from all areas of Tokyo. Three-quarters were male (n = 1823; 76.5%; the highest number of cases occurred among males aged 35–39 years and females aged 20–24 years. About a third of males (27% and females (32% reported never receiving rubella vaccination, with 68% and 56%, respectively, having an unknown vaccination status. Discussion: This outbreak reflects the changing, yet incomplete, immunization policies for rubella in Japan that may increase the risk of congenital rubella syndrome (CRS. To suppress the outbreak of rubella and prevent CRS cases, we recommend vaccination for the entire susceptible population.

  1. Corroborating a new probabilistic seismic hazard assessment for greater Tokyo from historical intensity observations

    Science.gov (United States)

    Bozkurt, S.; Stein, R.; Toda, S.

    2006-12-01

    The long recorded history of earthquakes in Japan affords an opportunity to forecast seismic shaking exclusively from past observations of shaking. For this we analyzed 10,000 intensity observations recorded during AD 1600-2000 in a 350 x 350 km area centered on Tokyo in a Geographic Information System. A frequency-intensity curve is found for each 5 x 5 km cell, and from this the probability of exceeding any intensity level can be estimated. The principal benefits of this approach is that it builds the fewest possible assumptions into a probabilistic seismic forecast, it includes site and source effects without imposing this behavior, and we do not need to know the size or location of any earthquake or the location and slip rate of any fault. The cost is that we must abandon any attempt to make a time-dependent forecast, which could be quite different. We believe the method is suitable to many applications of probabilistic seismic hazard assessment, and to other regions. The two key assumptions are that the slope of the observed frequency-intensity relation at every site is the same, and that the 400-year record is long enough to encompass the full range of seismic behavior. Tests we conduct suggest that both assumptions are sound. The resulting 30-year probability of IJMA>=6 shaking (roughly equivalent to PGA>=0.9 g or MMI=IX-X) is 30-40% in Tokyo, Kawasaki, and Yokohama, and 10-15% in Chiba and Tsukuba, the range reflecting spatial variability and curve-fitting alternatives. The strongest shaking is forecast along the margins of Tokyo Bay, within the river sediments extending northwest from Tokyo, and at coastal sites near the plate boundary faults. We also produce long- term exceedance maps of peak ground acceleration for building code regulations, and short-term hazard maps associated with hypothetical catastrophe bonds. Our results for greater Tokyo resemble our independent Poisson probability developed from conventional seismic hazard analysis, as well as

  2. Refletindo sobre a malformação congênita Refectindo sobre la malformación congénita Reflecting about congenital malformation

    Directory of Open Access Journals (Sweden)

    Rosângela da Silva Santos

    2005-10-01

    Full Text Available O estudo constituiu-se em uma revisão bibliográfica sobre malformações congênitas. Os objetivos consistem em fazer um levantamento da produção de enfermagem sobre o tema, apresentando as atuais contribuições referente às questões relacionadas as malformações congênitas e propiciar uma reflexão da atuação dos profissionais de enfermagem frente esta situação. Como resultados a revisão localizou estudos que foram categorizados em unidades temáticas: percepção materna, questões familiares, projeto de monitorização e assistência de enfermagem nas anomalias específicas. A conclusão aponta que a assistência adequada a ser prestada à criança com malformação congênita, demanda além de treinamento técnico, habilidade e sensibilidade da equipe multidisciplinar, o que a torna capaz de perceber e intervir na dimensão bio psicossocial e espiritual da criança e da família.Este estudio se constituye en una revisión bibliográfica sobre malformaciones congénitas. Los objetivos consisten en realizar un levantamiento de la producción de enfermería sobre el tema, presentando las actuales contribuciones referentes a los problemas relacionados a malformaciones congénitas y propiciar una reflexión de la actuación de los profesionales de enfermería frente a esta situación. La revisión nos dio como resultados diversos estudios, que fueron categorizados en las siguientes unidades temáticas: percepción materna, problemas familiares, proyecto de monitorización y asistencia de enfermería en las anomalías específicas. La conclusión muestra que la asistencia adecuada a ser brindada al niño con malformación congénita, demanda, además de entrenamiento técnico, habilidad y sensibilidad del equipo multidisciplinar, lo que le vuelve capaz de percibir e intervenir en la dimensión bio-psicosocial y espiritual del niño y de la familia.The study consisted in a bibliographical revision about congenital malformations. The

  3. Social Experiments in Tokyo Metropolitan Area Convection Study for Extreme Weather Resilient Cities(TOMACS)

    Science.gov (United States)

    Tsuyoshi, Nakatani; Nakamura, Isao; MIsumi, Ryohei; Shoji, Yoshinori

    2015-04-01

    Introduction TOMACS research project has been started since 2010 July in order to develop the elementary technologies which are required for the adaptation of societies to future global warming impacts that cannot be avoided by the reduction of greenhouse gases. In collaboration with related government institutions, local governments, private companies, and residents, more than 25 organizations and over 100 people are participated. TOMACS consists of the following three research themes: Theme 1: Studies on extreme weather with dense meteorological observations Theme 2: Development of the extreme weather early detection and prediction system Theme 3: Social experiments on extreme weather resilient cities Theme 1 aims to understand the initiation, development, and dissipation processes of convective precipitation in order to clarify the mechanism of localized heavy rainfall which are potential causes of flooding and landslides. Theme 2 aims to establish the monitoring and prediction system of extreme phenomena which can process real-time data from dense meteorological observation networks, advanced X-band radar network systems and predict localized heavy rainfalls and strong winds. Through social experiments, theme 3 aims to establish a method to use information obtained by the monitoring system of extreme phenomena to disaster prevention operations in order to prevent disasters and reduce damage. Social Experiments Toyo University is the core university for the social experiments accomplishment. And following organizations are participating in this research theme: NIED, the Tokyo Metropolitan Research Institute for Environmental Protection (TMRIEP), University of Tokyo, Tokyo Fire Department (TFD), Edogawa Ward in Tokyo, Yokohama City, Fujisawa City and Minamiashigara City in Kanagawa, East Japan Railway Company, Central Japan Railway Company, Obayashi Corporation, and Certified and Accredited Meteorologists of Japan(CAMJ). The social experiments have carried out

  4. Áreas de alta mortalidad perinatal debida a anomalías congénitas: análisis de estadísticas vitales, Colombia, 1999-2008

    Directory of Open Access Journals (Sweden)

    Sandra Patricia Misnaza

    2016-09-01

    Full Text Available Introducción. Durante 2012, las anomalías congénitas fueron la causa de 13 % de las muertes en menores de 28 días a nivel mundial y, en Colombia constituyeron la segunda causa de mortalidad infantil. Objetivo. Determinar la distribución geográfica de la mortalidad perinatal por anomalías congénitas en Colombia entre 1999 y 2008. Materiales y métodos. Se hizo un estudio descriptivo revisando los certificados de defunción de Colombia. La muerte perinatal se definió como muerte fetal y no fetal en niños con un peso de 500 g o más y 28 o menos días de edad, y las anomalías congénitas, como causa básica de la muerte (Clasificación Internacional de Enfermedades - CIE10: Q000 a Q999. La proyección nacional de nacimientos se tomó como el denominador de las tasas específicas. Se calcularon los percentiles para analizar las áreas de alta mortalidad (percentil de 90 o más. Resultados. Se encontraron 22.361 muertes perinatales por anomalías congénitas. Antioquia, Caldas, Risaralda, Huila, Quindío, Bogotá, Valle del Cauca y Guainía superaron, en promedio, el percentil 90 durante los diez años de estudio. Los municipios con mayores tasas de mortalidad fueron: Giraldo, Ciudad Bolívar, Riosucio, Liborina, Supía, Alejandría, Sopetrán, San Jerónimo, Santa Fe de Antioquia y Marmato, en donde oscilaron entre 205,81 y 74,18 por 10.000 nacimientos. Las tasas de mortalidad perinatal por 10.000 nacidos vivos fueron de 28,1 para el grupo de malformaciones del sistema circulatorio; de 13,7 para anomalías del sistema nervioso central, y de 7,0 para anomalías cromosómicas. Conclusión. La alta mortalidad perinatal por anomalías congénitas en la región andina requiere acciones urgentes de investigación sobre los posibles riesgos y medidas de prevención.

  5. Malformação adenomatóide quística congénita do pulmão ou malformação congénita das vias aéreas pulmonares

    OpenAIRE

    Vítor Sousa; Lina Carvalho

    2003-01-01

    RESUMO: A malformação adenomatóide quística congénita do pulmão corresponde a uma lesão hamartomatosa, facilmente reconhecível pela sua morfologia que permite identificar as três formas clássicas de Stocker et al (1977): tipos 1, 2 e 3 e actualmente com possibilidade de se interpretar como uma malformação espectral, de acordo com Yousem (2002), compreendendo cinco tipos, dependentes do nível a que ocorre a malformação na árvore tráqueo-broncopulmonar e, assim, aplicar a desig...

  6. Enuresis and Hyperactivity-Inattention in Early Adolescence: Findings from a Population-Based Survey in Tokyo (Tokyo Early Adolescence Survey.

    Directory of Open Access Journals (Sweden)

    Sho Kanata

    Full Text Available Enuresis (9% at age 9.5 negatively affects children's psychosocial status. Clinically-diagnosed enuresis (2% at the age is associated with hyperactivity-inattention, and common neural bases have been postulated to underlie this association. It is, however, unclear whether this association is applicable to enuresis overall among the general population of early adolescents when considered comorbid behavioral problems. We aimed to examine whether enuresis correlates with hyperactivity-inattention after controlling for the effects of other behavioral problems.Participants were 4,478 children (mean age 10.2 ± 0.3 years old and their parents from the Tokyo Early Adolescence Survey (T-EAS, a population-representative cross-sectional study conducted in Tokyo, Japan conducted from 2012 to 2015. Children's enuresis and behavioral problems, including hyperactivity-inattention (as measured by the Strength and Difficulties Questionnaire, were examined using parent-reporting questionnaires. Multivariate linear regression was used to explore whether enuresis predicts hyperactivity-inattention.The hyperactivity-inattention score was significantly higher in the enuretic group than the non-enuretic group (enuretic: M (SD = 3.8 (2.3, non-enuretic: M (SD = 3.0 (2.1, Hedge's g = 0.39, p < .001. This association remained significant even after controlling for other behavioral problems and including sex, age, intelligence quotient (IQ, low birth weight and parents' education (β = .054 [95% CI: .028-.080], p < .001.Enuresis was independently associated with hyperactivity-inattention in early adolescents among general population even when other behavioral problems were considered. These results suggest that, as with clinically-diagnosed cases, enuresis may predict need for screening and psychosocial support for hyperactivity-inattention.

  7. Enuresis and Hyperactivity-Inattention in Early Adolescence: Findings from a Population-Based Survey in Tokyo (Tokyo Early Adolescence Survey).

    Science.gov (United States)

    Kanata, Sho; Koike, Shinsuke; Ando, Shuntaro; Nishida, Atsushi; Usami, Satoshi; Yamasaki, Syudo; Morimoto, Yuko; Toriyama, Rie; Fujikawa, Shinya; Sugimoto, Noriko; Sasaki, Tsukasa; Furukawa, Toshiaki A; Hiraiwa-Hasegawa, Mariko; Kasai, Kiyoto

    2016-01-01

    Enuresis (9% at age 9.5) negatively affects children's psychosocial status. Clinically-diagnosed enuresis (2% at the age) is associated with hyperactivity-inattention, and common neural bases have been postulated to underlie this association. It is, however, unclear whether this association is applicable to enuresis overall among the general population of early adolescents when considered comorbid behavioral problems. We aimed to examine whether enuresis correlates with hyperactivity-inattention after controlling for the effects of other behavioral problems. Participants were 4,478 children (mean age 10.2 ± 0.3 years old) and their parents from the Tokyo Early Adolescence Survey (T-EAS), a population-representative cross-sectional study conducted in Tokyo, Japan conducted from 2012 to 2015. Children's enuresis and behavioral problems, including hyperactivity-inattention (as measured by the Strength and Difficulties Questionnaire), were examined using parent-reporting questionnaires. Multivariate linear regression was used to explore whether enuresis predicts hyperactivity-inattention. The hyperactivity-inattention score was significantly higher in the enuretic group than the non-enuretic group (enuretic: M (SD) = 3.8 (2.3), non-enuretic: M (SD) = 3.0 (2.1), Hedge's g = 0.39, p < .001). This association remained significant even after controlling for other behavioral problems and including sex, age, intelligence quotient (IQ), low birth weight and parents' education (β = .054 [95% CI: .028-.080], p < .001). Enuresis was independently associated with hyperactivity-inattention in early adolescents among general population even when other behavioral problems were considered. These results suggest that, as with clinically-diagnosed cases, enuresis may predict need for screening and psychosocial support for hyperactivity-inattention.

  8. Deficiencia congénita de proteína C en un recién nacido con trombosis y necrosis de tejidos extensa

    Directory of Open Access Journals (Sweden)

    Bárbara Acosta Batista

    Full Text Available Uno de los trastornos hematológicos más graves del período neonatal es la deficiencia congénita de proteína C, de presentación muy rara, y causa de enfermedad tromboembólica severa y púrpura fulminante en recién nacidos. Se puede sintetizar como una entidad clínico-patológica, de aparición aguda, con trombosis de la vasculatura de la dermis, lo cual conduce a necrosis hemorrágica y progresiva de la piel, asociada a coagulación intravascular diseminada y hemorragia perivascular, que ocurre en el período neonatal. El paciente presentado exhibe los elementos clínico-patológicos que caracterizan la púrpura fulminante, cuyo origen se debe a una deficiencia hereditaria de proteína C, lo cual condujo a la aparición de complicaciones trombóticas severas.

  9. Tratamiento simultáneo de anquilosis temporomandibular unilateral congénita y del microlaterognatismo asociado Simultaneously treament of congenital unilateral temporomandibular ankylosis and consecutive microlatherognathism

    Directory of Open Access Journals (Sweden)

    José Felipe Basulto Varela

    2013-03-01

    Full Text Available Este artículo tiene como objetivo reportar los resultados obtenidos a corto y largo plazo, del tratamiento con enfoque multidisciplinario de una anquilosis unilateral congénita de la articulación temporomandibular asociada a un síndrome de malformación embrionaria, en un niño de 12 años de edad, en el que se utilizó un distractor externo bidimensional con un doble propósito: como fijador para mantener el espacio logrado con la artroplastia y como distractor para elongar la rama mandibular hipotrófica, activado 5 días después de la osteotomía, con el objetivo de eliminar la anquilosis y el microlaterognatismo mandíbular consecutivo de ella, simultaneamente de manera funcional y dinámica.The paper reports the short- and long-term results obtained from the multidisciplinary treatment of a congenital unilateral ankylosis of the temporomandibular joint associated to an embryonic malformation in a 12-year-old boy, using an external bidimensional distraction device with a two-fold purpose: as fixator to maintain the space achieved by arthroplasty, and as distractor to elongate the hypotrophic mandibular branch, activated 5 days after osteotomy, with the purpose of eliminating ankylosis and consecutive mandibular microlaterognatism, both functionally and dynamically.

  10. RECIÉN NACIDO PORTADOR DE CARDIOPATÍA CONGÉNITA COMPLEJA. ANÁLISIS DE RIESGO, TOMA DE DECISIONES Y NUEVAS POSIBILIDADES TERAPÉUTICAS

    Directory of Open Access Journals (Sweden)

    Dr. Luis Cárdenas

    2016-07-01

    Full Text Available Se presenta en este artículo de revisión, un análisis de los factores a considerar en la toma de decisiones de manejo respecto a un grupo de pacientes portadores de cardiopatías congénitas complejas de muy alto riesgo, generalmente asociadas a comorbilidades y condiciones agravantes. Basándose en la experiencia de los autores, revisión de la literatura y casos clínicos ilustrativos, se sugieren posibilidades terapéuticas iniciales, poniendo énfasis en el análisis estrictamente caso a caso y las características que posea el centro de salud. Se proponen además nuevas posibilidades de tratamiento para el extremo del espectro en este grupo de recién nacidos, mostrando que una estrategia híbrida, quirúrgica-intervencional, es posible y segura para pacientes con bajo peso de nacimiento, anatomías extremadamente complejas o con comorbilidad asociada de alto riesgo. Para lograr éxito en este abordaje, es necesario que grupos multidisciplinarios se involucren en todo el proceso de diagnóstico y tratamiento.

  11. Preparedness for the Spread of Influenza: Prohibition of Traffic, School Closure, and Vaccination of Children in the Commuter Towns of Tokyo

    OpenAIRE

    Yasuda, Hidenori; Yoshizawa, Nobuaki; Kimura, Mikio; Shigematsu, Mika; Matsumoto, Masaaki; Kawachi, Shoji; Oshima, Masamichi; Yamamoto, Kenji; Suzuki, Kazuo

    2008-01-01

    In Greater Tokyo, many people commute by train between the suburbs and downtown Tokyo for 1 to 2 h per day. The spread of influenza in the suburbs of Tokyo should be studied, including the role of commuters and the effect of government policies on the spread of disease. We analyzed the simulated spread of influenza in commuter towns along a suburban railroad, using the individual-based Monte Carlo method, and validated this analysis using surveillance data of the infection in the Tokyo suburb...

  12. Leptospirosis infection in a homeless patient in December in Tokyo: a case report.

    Science.gov (United States)

    Kang, You Me; Hagiwara, Akiyoshi; Uemura, Tatsuki

    2015-09-16

    We report a case of severe leptospirosis that occurred during winter in Tokyo, the capital of Japan. Leptospirosis is endemic in tropical regions and extremely rare in the urban areas of Japan. Only six new cases were reported in Tokyo in 2014. Most leptospirosis cases reported in urban areas of Japan were a result of occupational hazards, and there is no previous report of leptospirosis in a homeless patient in Tokyo. We believe this report could provide a widened perspective about the clinical presentation and epidemiology of leptospirosis in Japan. Our patient was a 73-year-old Asian man. He had been homeless for over 10 years, with exposure to rodents and their excrement in parks and on the streets. He presented with fever and severe inflammatory response, satisfying the diagnostic criteria for systemic inflammatory response syndrome. Laboratory findings showed multiple-organ dysfunction, including renal failure, liver failure with increased total bilirubin level, and coagulopathy with decreased platelets. We suspected leptospirosis on the basis of these clinical findings. The diagnosis was also confirmed by polymerase chain reaction first, and paired antibody titers on day 9, in the recovery period, showed positive results for three species. Our patient's case suggests that even patients without a history of traveling abroad or exposure to freshwater can develop leptospirosis in winter in urban areas in Japan. If a patient has symptoms like fever, calf pain and MOF; as a differential diagnosis we should rule outthe Leptospirosis. From the perspective of sensitivity, specificity, and clinical convenience, polymerase chain reaction could be the preferred diagnostic tool of choice.

  13. Export of particulate matter from Tokyo Bay studied with radiochemical tracers, 210Po and 210Pb

    International Nuclear Information System (INIS)

    Kim, Young-Ill; Narita, Hisashi; Noriki, Shinichiro; Tsunogai, Shizuo

    1997-01-01

    Sediment traps were deployed at the mouth of Tokyo Bay in the winter of 1991 and the summer of 1993, each for a few days. The fluxes of total mass, 210 Pb (parent) and 210 Po (daughter) increased with depth, especially in the near-bottom layer. All the fluxes of total mass, 210 Po and 210 Pb decreased offshore at the same depth, while they increased offshore at the same distance above the bottom. The observed particulate flux of 210 Pb in the water column was one to two orders of magnitude larger than the sedimentation rate at the bottom. The activity ratio of 210 Po/ 210 Pb in the near-bottom layer was largest at each station and did not vary from station to station. These findings indicate that enormous amounts of particulate matter are transported fairly quickly offshore through the near-bottom layer at the entrance. The variation in total mass flux was well synchronized with the tidal cycle at a mid-depth of 85 m in the water column of 240 m in winter of 1991, where the fluxes were larger during ebb and smaller during flood tides. The particulate flux of 210 Po was also larger by a factor of about 2 during ebb, while the concentration of 210 Pb was about 40 % larger during flood than ebb. These findings indicate that the tidal current is a major conveyor of particulate matter at the mid-depths. The tidal variation, however, was weak for the results obtained in the near-bottom layer in 1993, where much particulate matter was transported toward the Kuroshio region along the valley of Tokyo Bay. Our results suggest that even bays having narrow mouths, such as Tokyo Bay, are a large source of particulate material to the open oceans. (author)

  14. Forecasting probabilistic seismic shaking for greater Tokyo from 400 years of intensity observations (Invited)

    Science.gov (United States)

    Bozkurt, S.; Stein, R. S.; Toda, S.

    2009-12-01

    The long recorded history of earthquakes in Japan affords an opportunity to forecast seismic shaking exclusively from past shaking. We calculate the time-averaged (Poisson) probability of severe shaking by using more than 10,000 intensity observations recorded since AD 1600 in a 350-km-wide box centered on Tokyo. Unlike other hazard assessment methods, source and site effects are included without modeling, and we do not need to know the size or location of any earthquake or the location and slip rate of any fault. The two key assumptions are that the slope of the observed frequency-intensity relation at every site is the same; and that the 400-year record is long enough to encompass the full range of seismic behavior. Tests we conduct here suggest that both assumptions are sound. The resulting 30-year probability of IJMA≥6 shaking (~PGA≥0.9 g or MMI≥IX) is 30-40% in Tokyo, Kawasaki, and Yokohama, and 10-15% in Chiba and Tsukuba. This result means that there is a 30% chance that 4 million people would be subjected to IJMA≥6 shaking during an average 30-year period. We also produce exceedance maps of peak ground acceleration for building code regulations, and calculate short-term hazard associated with a hypothetical catastrophe bond. Our results resemble an independent assessment developed from conventional seismic hazard analysis for greater Tokyo. Over 10000 intensity observations stored and analyzed using geostatistical tools of GIS. Distribution of historical data is shown on this figure.

  15. Assessing clinical outcomes of patients with acute calculous cholecystitis in addition to the Tokyo grading: a retrospective study.

    Science.gov (United States)

    Cheng, Wei-Chun; Chiu, Yen-Cheng; Chuang, Chiao-Hsiung; Chen, Chiung-Yu

    2014-09-01

    The management of acute cholecystitis is still based on clinical expertise. This study aims to investigate whether the outcome of acute cholecystitis can be related to the severity criteria of the Tokyo guidelines and additional clinical comorbidities. A total of 103 patients with acute cholecystitis were retrospectively enrolled and their medical records were reviewed. They were all classified according to therapeutic modality, including early cholecystectomy and antibiotic treatment with or without percutaneous cholecystostomy. The impact of the Tokyo guidelines and the presence of comorbidities on clinical outcome were assessed by univariate and multivariate regression analyses. According to Tokyo severity grading, 48 patients were Grade I, 31 patients were Grade II, and 24 patients were Grade III. The Grade III patients had a longer hospital stay than Grade II and Grade I patients (15.2 days, 9.2 days, and 7.3 days, respectively, p Tokyo severity, higher Charlson's Comorbidity Score, and encountering complications had a longer hospital stay. Based on treatment modality, surgeons selected the patients with less severity and fewer comorbidities for cholecystectomy, and these patients had a shorter hospital stay. In addition to the grading of the Tokyo guidelines, comorbidities had an additional impact on clinical outcomes and should be an important consideration when making therapeutic decisions. Copyright © 2014. Published by Elsevier B.V.

  16. Epidemiological characteristics of rubella and congenital rubella syndrome in the 2012-2013 epidemics in Tokyo, Japan.

    Science.gov (United States)

    Sugishita, Yoshiyuki; Shimatani, Naotaka; Katow, Shigetaka; Takahashi, Takuri; Hori, Narumi

    2015-01-01

    A large rubella outbreak has been observed since June 2012 in Tokyo, Japan, and a rapid increase in the number of congenital rubella syndrome (CRS) cases have also been reported in Japan since October 2012. All the clinically diagnosed and laboratory-confirmed rubella cases reported in Tokyo from January 2012 to December 2013 and all the laboratory-confirmed CRS cases from January 2012 to March 2014 were analyzed. In total, 4,116 rubella cases were reported in Tokyo. Of these, 77.2% (n=3,176) were male; the highest number of cases occurred in males aged 35-39 years and in females aged 20-24 years. Complications included arthralgia/arthritis (19.4%), thrombocytopenic purpura (0.5%), hepatic dysfunction (0.3%), and encephalitis (0.1%). The circulating rubella virus in Tokyo was genotype 2B. The most possible site of transmission was the workplace. Because of the rubella epidemic, 16 CRS cases were reported in Tokyo from March 2013 to February 2014. Domestic infection with rubella was proven for all mothers of 16 cases. This situation suggests that Japan is still working to achieve rubella elimination.

  17. Flight Model Development of Tokyo Tech Nano-Satellite Cute-1.7 + APD II

    Science.gov (United States)

    Ashida, Hiroki; Nishida, Junichi; Omagari, Kuniyuki; Fujiwara, Ken; Konda, Yasumi; Yamanaka, Tomio; Tanaka, Yohei; Maeno, Masaki; Fujihashi, Kota; Inagawa, Shinichi; Miura, Yoshiyuki; Matunaga, Saburo

    The Laboratory for Space Systems at the Tokyo Institute of Technology has developed the nano-satellite Cute-1.7+APD. The satellite was launched by JAXA M-V-8 rocket on February 22, 2006 and operated for about a month. A successor to the Cute-1.7+APD was developed and is named Cute-1.7+APD II. This new satellite is based on its predecessor but has some modifications. In this paper an overview of the Cute-1.7 series and flight model development of Cute-1.7+APD II are introduced.

  18. A new apparatus at hyper irradiation research facility at the Atomic Research Center, University of Tokyo

    International Nuclear Information System (INIS)

    Shibata, Hiromi; Iwai, Takeo; Narui, Makoto; Omata, Takao

    1996-01-01

    In the hyper irradiation research facility at the Atomic Research Center, the University of Tokyo, following apparatuses were newly installed for accelerator relating apparatus on 1995 fiscal year; 1) Hyper ion microbeam analysis apparatus, 2) Fourier conversion infrared microscopy, 3) Pico second two-dimensional fluorescence measuring apparatus, 4) Femto second wave-length reversible pulse laser radiation apparatus, and others. In addition to double irradiation, pulse beam irradiation experiment and so forth characteristic in conventional hyper irradiation research apparatus, upgrading of material irradiation experiments using these new apparatuses are intended. (G.K.)

  19. The Griffis' Journal of Tokyo Years (1873/4/1-1874/9/17)(No.2)

    OpenAIRE

    藏原, 三雪; Miyuki, KURAHARA

    2006-01-01

    This Griffis' Journal was written by W. E. Griffis (1843, 9, 17~1928, 2, 5) from April 1st, 1873 to September 17th, 1874. It is a continuation of the last issue. W. E. Griffis came to Japan in Dec.30 1870, after he had studied the new Scientific curriculum at Rutgers University in N.J. He was an American teacher (Yatoi) who had taught Japanese boys Chemistry and Physics etc. at Meishinkan (Fukuihan Hanko) and Nanko-Kaisei Gakko, the precursor of Tokyo Imperial University. This Journal is the ...

  20. Thermal comfort along the marathon course of the 2020 Tokyo Olympics.

    Science.gov (United States)

    Honjo, Tsuyoshi; Seo, Yuhwan; Yamasaki, Yudai; Tsunematsu, Nobumitsu; Yokoyama, Hitoshi; Yamato, Hiroaki; Mikami, Takehiko

    2018-04-17

    The Olympic Games will be held in Tokyo in 2020 and the period will be the hottest period of the year in Japan. Marathon is a sport with a large heat load, and it is said that the risk of heat stroke rises more than other sports activities. The thermal environment of the 2020 Tokyo Olympic marathon course is analyzed by using wet-bulb globe temperature (WBGT) and Universal Thermal Climate Index (UTCI) map of the center area of Tokyo. The change due to the place, the effect of the shadow of the building, and the position on the course was analyzed from the distribution of WBGT and UTCI in the short-term analysis of sunny day from August 2 to August 6, 2014. To make the distribution map, we calculated distributions of sky view factor and mean radiant temperature of the 10 km × 7.5 km analyzed area in the center of Tokyo. Distributions of air temperature and humidity are calculated from Metropolitan Environmental Temperature and Rainfall Observation System data, which is a high-resolution measurement network. It was possible to incorporate the local variation of temperature and humidity of the analyzed area. In the result, the WBGT is about 1 °C lower and the UTCI is about 4-8 °C lower in the shadow of buildings from 9:00 to 10:00 than in the sunny side. As a cooling method, making a shadow is a relatively effective method. The variation along the course considering the distribution of meteorological data within the area is about 0.5 °C WBGT and 1 °C UTCI range. If we allow the error of this range, one-point meteorological data can be applied for the estimation along the course. Passing the right side (left side in the case of return) of the course could keep the accumulated value slightly lower along the course in the morning because the marathon course roughly runs from west to east and buildings' shadow is on the relatively right side (south side). But practically, the effect of changing the position on the course was small. The long-term analysis on

  1. Analisis Kinerja Kontrak Berjangka Komoditi pada Tokyo Grain Exchange – Jepang

    OpenAIRE

    Soemapradja, Tomy G

    2005-01-01

    Futures contract is one of derivative instruments in which its value depends on underlying asset’s price fluctuation in the future. At the beginning, the futures contracts were traded with hedging motive, but now they are traded with speculative motive also. As an agricultural nation, finally, Indonesia has a commodity futures exchange (BBJ) by the end of 2000. Low volume of transactions and less futures alternative on BBJ made Tokyo Grain Exchange (TGE) as the object of this research. The st...

  2. Thermal comfort along the marathon course of the 2020 Tokyo Olympics

    Science.gov (United States)

    Honjo, Tsuyoshi; Seo, Yuhwan; Yamasaki, Yudai; Tsunematsu, Nobumitsu; Yokoyama, Hitoshi; Yamato, Hiroaki; Mikami, Takehiko

    2018-04-01

    The Olympic Games will be held in Tokyo in 2020 and the period will be the hottest period of the year in Japan. Marathon is a sport with a large heat load, and it is said that the risk of heat stroke rises more than other sports activities. The thermal environment of the 2020 Tokyo Olympic marathon course is analyzed by using wet-bulb globe temperature (WBGT) and Universal Thermal Climate Index (UTCI) map of the center area of Tokyo. The change due to the place, the effect of the shadow of the building, and the position on the course was analyzed from the distribution of WBGT and UTCI in the short-term analysis of sunny day from August 2 to August 6, 2014. To make the distribution map, we calculated distributions of sky view factor and mean radiant temperature of the 10 km × 7.5 km analyzed area in the center of Tokyo. Distributions of air temperature and humidity are calculated from Metropolitan Environmental Temperature and Rainfall Observation System data, which is a high-resolution measurement network. It was possible to incorporate the local variation of temperature and humidity of the analyzed area. In the result, the WBGT is about 1 °C lower and the UTCI is about 4-8 °C lower in the shadow of buildings from 9:00 to 10:00 than in the sunny side. As a cooling method, making a shadow is a relatively effective method. The variation along the course considering the distribution of meteorological data within the area is about 0.5 °C WBGT and 1 °C UTCI range. If we allow the error of this range, one-point meteorological data can be applied for the estimation along the course. Passing the right side (left side in the case of return) of the course could keep the accumulated value slightly lower along the course in the morning because the marathon course roughly runs from west to east and buildings' shadow is on the relatively right side (south side). But practically, the effect of changing the position on the course was small. The long-term analysis on the

  3. Mental Health Problems among Undergraduates in Fukushima, Tokyo, and Kyoto after the March 11 Tohoku Earthquake.

    Science.gov (United States)

    Ishikawa, Shin-ichi; Motoya, Ryo; Sasagawa, Satoko; Takahashi, Takahito; Okajima, Isa; Takeishi, Yasuchika; Essau, Cecilia A

    2015-06-01

    On March 11, 2011, the Great East Japan Earthquake devastated the Tohoku region, which led to a tsunami and a nuclear disaster. While these three disasters caused tremendous physical damage, their psychological impact remains unclear. The present study evaluated traumatic responses, internalizing (i.e., anxiety and depression), and externalizing (i.e., anger) symptoms among Japanese young people in the immediate aftermath and 2.5 years later. A total of 435 undergraduates were recruited from universities in three differentially exposed regions: Fukushima, Tokyo, and Kyoto. They completed a set of questionnaires retrospectively (i.e., September to December 2013) to measure their traumatic responses, anxiety and depressive symptoms, functional impairment, and anger immediately after the disaster and 2.5 years later. Participants in Tokyo had the highest level of traumatic response and internalizing symptoms immediately after the earthquake, whereas those in Fukushima had significantly higher levels of trait anger, anger-in (holding one's anger in), and anger-out (expressing one's anger externally). In Kyoto, the levels of anxiety and depression after 2.5 years were significantly higher than they were immediately after the disasters. In conclusion, anger symptoms were high among young people who lived at or near the center of the disasters, while anxiety and depression were high among those who lived far away from the disasters. These findings suggest the importance of providing mental health services to young people who did not live near the disaster area as well as to those living in the directly affected area.

  4. Resilience with Mixed Agricultural and Urban Land Uses in Tokyo, Japan

    Directory of Open Access Journals (Sweden)

    Giles Bruno Sioen

    2018-02-01

    Full Text Available Urban agriculture can enhance the resilience of neighborhoods by providing fresh food in times of natural disasters; however, there is little empirical evidence to support this. Therefore, this study proposes a methodology to identify patterns of agricultural production in urban areas by quantifying self-sufficiency rates in vegetable weight and key nutrients. A spatial grid cell analysis using a geographic information system (GIS identifies the current and potential self-sufficiency of each land use pattern in Tokyo. In a total of 1479 grid cells, the dominant land use and locations of 49,263 agricultural plots led to the categorization of six distinguishable land use patterns. The results showed that Tokyo has a fruit and vegetable self-sufficiency of 4.27% and a potential of 11.73%. The nutritional self-sufficiency of selected nutrients was the highest in vitamin K (6.54%, followed by vitamin C (3.84% and vitamin A (1.92%. Peri-urban areas showed the highest resilience in relation to aggregated risks and population density because of the mixture in agricultural and urban land uses.

  5. Impact of energy consumption on urban warming and air pollution in Tokyo metropolitan area

    International Nuclear Information System (INIS)

    Saitoh, T.S.; Hoshi, H.

    1995-01-01

    The rapid progress of industrialization and urbanization due to economic growth and concentration of social function in the urban areas in Japan have had an adverse effect on the urban environment. In most cities, it has become evident that the increase in energy consumption is causing environmental problems, including a temperature rise in the urban atmosphere (urban heat island) and air pollution. This paper reports the results of field observations and three dimensional simulations of the urban heat island using a three-dimensional modelling vorticity-velocity vector potential formation, in the Tokyo metropolitan area. According to the simulation for urban warming in the study area for the year 2031, the maximum temperature of a summer evening (18:00) would exceed 43 degrees celsius, indicating that Tokyo would no longer be comfortable for its inhabitants. It is concluded that in the near future, the problem of the urban heat island will become a more important issue than that of global warming because the rate of urban warming is greater. For this reason, the urban heat island could be fatal to humans unless resolved in the near future. (author). 1 tab., 11 figs., 18 refs

  6. Urban warming in Tokyo area and counterplan to improve future environment

    International Nuclear Information System (INIS)

    Saitoh, T.S.; Hoshi, H.

    1993-01-01

    The rapid progress in industrialization and concentration of economic and social functions in urban areas has stimulated a consistent increase in population and energy consumption. The sudden urbanization in modern cities has caused environmental problems including alternation of the local climate. This is a phenomenon peculiar to the urban areas, and is characterized by a consistent rise in the temperature of the urban atmosphere, an increase in air pollutants, a decrease in relative humidity, and so on. The phenomenon characterized by a noticeable temperature rise in the urban atmosphere has been called the urban heat island and analyzed by both observational and numerical approaches. The numerical model can be classified into two ways: the mechanical model and energy balance model. Since Howard reported on the urban heat island in London, there have been a number of observational studies and numerical studies based on the two-dimensional modeling. Recently, three-dimensional studies have been reported simultaneously with great the advancement of the supercomputer. The present paper reports the results of the field observation by automobiles in the Tokyo metropolitan area and also the results of the three-dimensional simulation for urban warming in Tokyo at present and in the future around 2030. Further, the authors also present the results of a simulation for the effect of tree planting and vegetation

  7. [A study of the mentally ill in institutions for homeless people in Tokyo].

    Science.gov (United States)

    Hashimoto, A

    1992-08-01

    Homeless problems associated with poverty may be considered almost resolved in Japan because of the post World War II economic development, but in large cities such as Tokyo the homeless are still being produced, a reflection of a variety of social problems. This study is based on an analysis of admission records of an institution for the homeless which was established in 1952 in Tokyo. Subjects are 2,122 single persons who were admitted between 1952 and 1985. Among these, 136 are mentally ill persons, who are the main subjects of analysis in this study. Results show that, which after 1970 the number of the mentally ill significantly increased, many of those people dropped out of the institution mostly because they were originally admitted directly from discharge from hospitals because there was no other place to go except the institutions, and also because the institution, originally meant to house street people who had been detained, did not offer appropriate programs for the mentally ill. A solution to these problems requires that roles of institutions for the homeless and subjects admitted be reconsidered. Institution staff should enrich programs designed for the homeless mentally ill and help them organize their social network and live in the community.

  8. Characteristics of sudden unexpected cancer deaths investigated by medical examiners in Tokyo, Japan (2009).

    Science.gov (United States)

    Suzuki, Hideto; Tanifuji, Takanobu; Abe, Nobuyuki; Fukunaga, Tatsushige

    2014-01-01

    Annually, about 400 cases of sudden unexpected death are attributed to cancer in Tokyo, Japan. These individuals may have been undiagnosed, or their medical conditions may not have been carefully evaluated before death. We examined medical consultations, cancer diagnoses, and economic status of all cancer deaths investigated by medical examiners in 2009. Among cases handled by the Tokyo Medical Examiner's Office in 2009 (N = 12 493), records for all cases of cancer death (n = 400) were reviewed to determine the extent of medical care provided, diagnosis before death, and economic status of the decedent. Most of the decedents (n = 232; 58%) had received a diagnosis of terminal/advanced cancer during a medical consultation. Most did not receive such medical consultations at home, despite their very weak physical condition. However, nearly one quarter of decedents (24%; 95/400) had not received a cancer diagnosis before death. The proportions of decedents who had been indigent, received no medical consulting, and had colon cancer were significantly higher among undiagnosed cases than among diagnosed cases. Indigent persons were the largest subgroup (n = 19; 43%) among those who had never received a medical consultation (n = 44). In addition, the proportion of those who had discontinued or received no medical consultation was higher among indigent persons than among non-indigent persons. The quality of medical services for cancer patients could be improved by educating general practitioners about terminal care, expanding efforts to monitor and diagnose cancer, especially among indigent patients, and increasing participation rates for colorectal cancer screening.

  9. [Kiken drugs: current status of abuse among youth in the nightlife areas of Tokyo].

    Science.gov (United States)

    Shimane, Takuya

    2015-09-01

    The abuse of "Kiken drugs," including synthetic cannabinoids, is a serious and growing social problem in Japan. Kiken drugs is the general term for novel psychoactive substances that have not been designated as illegal by Japanese law. The aim of this article is to describe the current status of the abuse of Kiken drugs by youth in the nightlife areas of Tokyo. An anonymous field-based survey was conducted using laptop computers at four dance parties in Tokyo, Japan. The questionnaires were completed by 307(44% female, mean age 30.9 years) young adults at the dance parties. Among the survey participants, 24.4% reported Kiken drug use (herbs 22.8%, powders 7.2%, and liquids 3.3%) in their lifetime. The primary reasons for Kiken drug use were peer pressure (37.3%), and avoiding penalties for possession of illegal drugs under Japanese laws (28.0%). In addition, 61.3% reported obtaining Kiken drugs from close friends. Our results clearly suggest that young adults at dance parties have a higher lifetime prevalence of Kiken drug use than the Japanese general population (0.4% reported in 2013). As the social stigma associated with drug use is extremely high in Japan, avoiding illegal drugs prohibited by law by using easily available Kiken drugs may be more socially acceptable among youth in the nightlife areas.

  10. History of ancient megathrust earthquakes beneath metropolitan Tokyo inferred from coastal lowland deposits

    Science.gov (United States)

    Mannen, Kazutaka; Yoong, Kim Haeng; Suzuki, Shigeru; Matsushima, Yoshiaki; Ota, Yuki; Kain, Claire L.; Goff, James

    2018-02-01

    Metropolitan Tokyo is located directly above a subduction zone that has generated two megathrust earthquakes in the past 300 years. However, the timing of older megathrusts on this margin is poorly understood. In this study, we aim to constrain the timings of past megathrust earthquakes, using coastal stratigraphy, paleoecology, radiocarbon dating and archaeological records from coastal lowlands. An investigation of 13 boreholes in the southern coastal area of metropolitan Tokyo found evidence for 4 m of uplift in a 6000-year period. However, we found that net vertical displacement in the last 1000 years is approximately zero. Results suggest that preservation of usually ephemeral lagoon sediments occurred on three occasions in the past 1000 years, and radiocarbon dating results show that the timings of these preservation episodes are close to that of major historical earthquakes. We thus attribute the intermittent preservation of the ephemeral lagoon deposits to coseismic uplift caused by the megathrust earthquakes. The candidates of the megathrust earthquakes are events that took place in 1703 CE, the 13th century, and 878 CE. Since these events produced no net vertical displacement due to inter-seismic subsidence, we propose that earthquakes responsible for long-term uplift of this region took place prior to the 9th century. This research also demonstrates the value of preserved intertidal sediments as paleoseismological archives where net tectonic displacement is neutral.

  11. Time trends of perfluorinated compounds from the sediment core of Tokyo Bay, Japan (1950s-2004)

    Energy Technology Data Exchange (ETDEWEB)

    Zushi, Yasuyuki; Tamada, Masafumi [Graduate School of Environment and Information Sciences, Yokohama National University, 79-7 Tokiwadai, Hodogaya, Yokohama 240-8501 (Japan); Kanai, Yutaka [Geological Survey of Japan, National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba 305-8567 (Japan); Masunaga, Shigeki, E-mail: masunaga@ynu.ac.j [Graduate School of Environment and Information Sciences, Yokohama National University, 79-7 Tokiwadai, Hodogaya, Yokohama 240-8501 (Japan)

    2010-03-15

    Perfluorinated compounds (PFCs) were detected in sediment core samples collected in Tokyo Bay to reveal their time trends. The core sample deposited during 1950s-2004 was divided into two- to three-year intervals and the concentrations of 24 types of PFCs were determined. Perfluorooctane sulfonate (PFOS) decreased gradually from the early 1990s and its precursor decreased rapidly in the late 1990s, whereas perfluorooctanoic acid (PFOA) increased rapidly. The observed trends were regarded as a reflection of the shift from perfluorooctyl sulfonyl fluoride (PFOSF)-based products to telomer-based products after the phaseout of PFOSF-based products in 2001. The branched isomers of perfluoroundecanoic acid (PFUnDA) and perfluorotridecanoic acid (PFTrDA) were detected in the sample with its ratio of linear-isomer/branched-isomer concentrations decreasing. In this study, we revealed that the sediment core can serve as a tool for reconstructing the past pollution trend of PFCs and can provide interesting evidence concerning their environmental dynamics and time trend. - This study reports the time trends of the concentrations of 24 species of PFCs, including FTCA, FTUCA and FOSAA, in a sediment core of Tokyo Bay, Japan.

  12. Annual report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1996

    International Nuclear Information System (INIS)

    1997-08-01

    This report summarizes research and educational activities, operation status of the research facilities of the Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo on fiscal year 1996. This facility has four major research facilities such as fast neutron source reactor 'Yayoi', electron Linac, fundamental experiment facility for nuclear fusion reactor blanket design and high fluence irradiation facility(HIT). Education and research activities are conducted in a wide fields of nuclear engineering using these facilities. The former two facilities are available for various studies by universities all over Japan, facility for nuclear fusion reactor blanket design is utilized for research within the Faculty of Engineering and HIT is used for the research within the University of Tokyo. The facility established a plan to reorganized into a nation wide research collaboration center in fiscal year 1995 and after further discussion of a future program it is decided to hold 'Nuclear energy symposium' periodically after fiscal year 1997 as a part of the activity for appealing the research results to the public. (G.K.)

  13. The introduction of hydrogen in London and Tokyo: costs and strategic issues

    International Nuclear Information System (INIS)

    Hart, David; Hutchinson, David

    1998-01-01

    While the proposals made in this work are no more than tentative at this stage, especially in the light of unfinished analysis of the situation in Tokyo, they represent an initial perspective on some strategies and policies affecting the potential introduction of hydrogen into the energy system of an urban area. It has been shown that given certain assumptions the introduction of hydrogen into an urban energy infrastructure could be both environmentally beneficial and economically viable. In order to achieve this introduction several possible strategies have been proposed, although none of these has been tested in detail. These strategies are highly likely to vary between different urban areas depending on the prevailing conditions. Specific analysis on the conditions in Tokyo will be carried out in the near future. This should enable the qualitative evaluation of some of the proposals already made, and suggestion of new ones. At the same time, the transferability both of the methodology used for analysing London and the strategies suggested for the early introduction of hydrogen will be examined. (author)

  14. The Tokyo subway sarin attack: disaster management, Part 1: Community emergency response.

    Science.gov (United States)

    Okumura, T; Suzuki, K; Fukuda, A; Kohama, A; Takasu, N; Ishimatsu, S; Hinohara, S

    1998-06-01

    The Tokyo subway sarin attack was the second documented incident of nerve gas poisoning in Japan. Prior to the Tokyo subway sarin attack, there had never been such a large-scale disaster caused by nerve gas in peacetime history. This article provides details related to how the community emergency medical services (EMS) system responded from the viewpoint of disaster management, the problems encountered, and how they were addressed. The authors' assessment was that if EMTs, under Japanese law, had been allowed to maintain an airway with an endotracheal tube or use a laryngeal mask airway without physician oversight, more patients might have been saved during this chemical exposure disaster. Given current legal restrictions, advanced airway control at the scene will require that doctors become more actively involved in out-of-hospital treatment. Other recommendations are: 1) that integration and cooperation of concerned organizations be established through disaster drills; 2) that poison information centers act as regional mediators of all toxicologic information; 3) that a real-time, multidirectional communication system be established; 4) that multiple channels of communication be available for disaster care; 5) that public organizations have access to mobile decontamination facilities; and 6) that respiratory protection and chemical-resistant suits with gloves and boots be available for out-of-hospital providers during chemical disasters.

  15. Taquicardia ectópica congénita de la unión: Tratamiento farmacológico en el primer año de vida

    Directory of Open Access Journals (Sweden)

    Mónica N. Benjamín

    2011-12-01

    Full Text Available La forma congénita de la taquicardia ectópica de la unión (TEU es una arritmia poco frecuente que suele presentar dificultades en su manejo farmacológico, con altas tasas de morbilidad y mortalidad. El objetivo de este trabajo fue informar la experiencia en el seguimiento y el tratamiento de esta forma de taquicardia supraventricular en pacientes menores de un año. Se identificaron siete pacientes con TEU congénita en 28 meses de seguimiento entre 2008 y 2010. El diagnóstico fue realizado en el primer día de vida en cuatro pacientes y dentro de los 150 días de vida en los 3 restantes. Sólo dos presentaron miocardiopatía dilatada. Ninguno presentó cardiopatía estructural. Se utilizó amiodarona en todos los pacientes, en un caso como única droga, asociándose a propanolol en cuatro. En un paciente se asoció flecainida a estos dos fármacos y en otro se la combinó con amiodarona. En un tiempo de seguimiento con un rango de 1-28 meses (media 12.2 meses, mediana 9.75 meses en tres de los pacientes se consiguió obtener ritmo sinusal alternante con taquicardia nodal lenta; ninguno presentó efectos adversos secundarios a la medicación, ni deterioro de la función ventricular. Hubo sólo una muerte en el grupo estudiado. En conclusión, la combinación de fármacos antiarrítmicos (amiodarona más propranolol y eventualmente flecainida constituye una alternativa válida para un adecuado control de la TEU congénita en pacientes menores de un año de edad.

  16. Transmisión vectorial y congénita del Trypanosoma cruzi en Las Lomitas, Formosa Vectorial and congenital transmission of Trypanosoma cruzi in Las Lomitas, Formosa

    Directory of Open Access Journals (Sweden)

    Sergio Sosa-Estani

    2009-10-01

    Full Text Available La enfermedad de Chagas causada por el Trypanosoma cruzi es una causa importante de morbimortalidad en Latino América. El objetivo de este estudio fue describir las tasas de infestación en las viviendas de cuatro comunidades aborígenes de Las Lomitas (Región del Gran Chaco, Formosa, Argentina; la tasa de infección en la población infantil residente en las mismas, en donantes de sangre y en mujeres embarazadas que asistieron al Hospital de Las Lomitas y la tasa de infección congénita de niños nacidos de mujeres infectadas durante el período de estudio. La tasa de infestación en 172 viviendas evaluadas en 2006 alcanzó el 32%. La prevalencia de infección en 445 personas fue de 17.5% y en menores de 5 años de edad fue 8.6%. La tasa de infección en donantes de sangre alcanzó a 18.6% y en mujeres embarazadas fue 29.1%. La tasa de infección considerada congénita en 47 niños nacidos de mujeres infectadas residentes en viviendas bajo vigilancia fue de 17.0%. El estudio mostró, al momento de su inicio, índices compatibles con transmisión vectorial activa. Después del control vectorial con insecticidas, la tasa de infestación se redujo a 3.3%. El sistema de salud local incorporó procedimientos de prevención primaria y secundaria para evitar nuevos casos e instaurar el tratamiento de la población infectada.Chagas disease, caused by Trypanosoma cruzi, is a major cause of morbidity and mortality in Latin America. The objective of this study was to describe the rate of infestation in four aboriginal communities in Las Lomitas (Great Chaco Region, Formosa, Argentina; the rate of infection in children residing in these communities, in blood donors and in pregnant women who received care at the Hospital Las Lomitas, as well as the rate of congenital infection in children born to women infected during the study period. The rate of infestation of 172 households evaluated in 2006 reached 32%. Prevalence of infection among 445 people was 17

  17. Sífilis materna y congénita en cuatro provincias de Bolivia Maternal and congenital syphilis in four provinces in Bolivia

    Directory of Open Access Journals (Sweden)

    Rita Revollo

    2007-12-01

    Full Text Available OBJETIVO: Calcular las frecuencias de sífilis materna y congénita, transmisión del agente etiológico de la madre al recién nacido, y variables asociadas con la enfermedad, en seis hospitales públicos en Bolivia. MATERIAL Y MÉTODOS: Se realizó un estudio transversal de mayo a septiembre de 2004. Se administró la prueba rápida para sífilis Determine-TP y RPR cuantitativo a mujeres postparto sin RPR previo. Se incluyeron antecedentes demográficos y de atención prenatal de embarazos previos. A los recién nacidos de madres con sífilis se les practicó Western Blot IgM p47 y ELISA IgM. Las pruebas serológicas se procesaron en el Laboratorio Nacional de Referencia (INLASA. Se realizó un análisis estadístico bivariado y multivariado para establecer asociaciones con el diagnóstico positivo a T. pallidum. RESULTADOS: La prevalencia de sífilis entre 1 594 mujeres postparto fue de 7.2%, con una proporción de transmisión de infección de madres a recién nacidos de 15.7 por ciento. La prevalencia de sífilis congénita por serología fue de 1.1%; 94% de estos neonatos no presentaron sintomatología. A pesar de una cobertura de control prenatal de 70.5% en Bolivia, aún existen mujeres que acuden directamente al parto institucional sin contar con tamizaje previo para sífilis con pruebas de rutina. El bajo nivel de instrucción formal (OBJECTIVE: Assess frequencies of maternal and congenital syphilis, mother-child transmission and variables associated with syphilis in six urban hospitals in Bolivia. MATERIAL AND METHODS: A cross-sectional study was performed between May and September 2004. We administered the Abbot Determine-TP rapid test and quantitative RPR to postpartum women without prior RPR. Sociodemographic variables and prior prenatal care visits were studied. Newborns of syphilis positive mothers were studied with Western Blot IgM p47 and ELISA IgM. Serum samples were analyzed at the Central Reference Laboratory (INLASA

  18. Frecuencia y factores de riesgo asociados a desnutrición de niños con cardiopatía congénita

    Directory of Open Access Journals (Sweden)

    Villasís-Keever Miguel Angel

    2001-01-01

    Full Text Available Objetivo. Determinar la frecuencia y factores asociados a desnutrición en niños con cardiopatía congénita (CC. Material y métodos. Estudio transversal analítico, hecho entre agosto de 1997 y mayo de 1998, en el servicio de cardiopatías congénitas del hospital de Cardiología del Centro Médico Nacional Siglo XXI, del Instituto Mexicano del Seguro Social de la Ciudad de México, México, a 244 menores de 17 años, de ambos sexos, con diagnóstico de CC y sin otras malformaciones. El estado de nutrición se evaluó mediante los índices peso/edad (P/E, talla/edad (T/E y peso/talla (P/T, y se definió desnutrición con puntuaciones Z mayores a -2. Se consideraron factores de riesgo: edad, sexo, antecedentes perinatales, historia de alimentación, administración de suplementos nutricios, estado socioeconómico y funcionalidad y composición de la familia. Se formaron cuatro grupos de CC: acianógenas con flujo pulmonar aumentado (AFPA o con flujo pulmonar normal (AFPN; cianógenas con flujo pulmonar aumentado (CFPA o disminuido (CFPD. Análisis estadístico: ji cudrada, U-Mann Whitney, Kruskal-Wallis. Se aplicó regresión logística para el control de las variables de confusión y se calculó razón de momios (RM e intervalos de confianza al 95% (IC 95%. Resultados. El grupo de AFPA (62.7% fue el más frecuente, seguido por CFPD (15.6%, AFPN (11.5% y CFPA (10.2%; con P/E, 40.9% tuvieron desnutrición; con T/E, 24.6%; y con P/T, 31.1%. Los grupos más afectados fueron los lactantes y los ninos con CFPA. Los factores asociados a desnutrición fueron: presencia de cardiopatía cianógena (RM 2.54; IC 95% 0.98-6.58 y la falta de administración de algún complemento nutricio (RM 2.38; IC 95% 1.06-5.34. Entre mayor número de miembros en una familia (RM 1.42; IC 95% 0.99-2.05 mayor frecuencia de desnutrición; a mayor edad menor riesgo de desnutrición (RM 0.92; IC 95% 0.89-0.96. Conclusiones. La desnutrición en niños con CC es frecuente; es

  19. Results of photovoltaic power generation system operation in Tokyo Electric Power Company; Tokyo Denryoku ni okeru taiyoko hatsuden setsubi no unten jisseki ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Fukuda, H.; Itokawa, K. [Tokyo Electric Power Co. Inc., Tokyo (Japan)

    1996-10-27

    A report was made on the measurement of data and the results of the analysis at 14 sites of photovoltaic power generation facilities operated under system interconnection by Tokyo Electric Power Company. This type of system is provided in 40 sites as of the end of fiscal 1995, generating 479kw. The items measured were the generated electric energy at all 14 sites, and the quantity of solar radiation, outside air temperature, panel temperature, etc., at limited sites; and the capacity of each equipment, azimuth and inclination of the panel were also recorded simultaneously. Hourly values were used for the analysis. Five minute values were utilized, however, in the examination of the cause of lowered output and in the situation recognition of the influence of the shade or the change of weather. The utilization factor of the facilities was in the average 10.8% in fiscal 1994 and 10.7% in fiscal 1995. The factor decreased slightly unless the panel azimuth faced due south. The utilization factor at the panel inclination of 35 degrees and 45 degrees showed both 10.4% through the year making no difference. The system seemed to show no overwhelming possibilities in coping with electric power demand. The reason was that deviation existed for 2 hours or so in the peak and that reliability was low as basic power facilities. However, it was determined that the system be continuously examined in future. 9 figs., 1 tab.

  20. Efectos en el desarrollo pulmonar de la oclusión traqueal precoz como terapia fetal de la hipoplasia pulmonar en la hernia diafragmática congénita del feto ovino /

    OpenAIRE

    Giné Prades, Carles,

    2017-01-01

    Introducción: La oclusión traqueal mediante la colocación fetoscópica de un balón endotraqueal a las 26-29 semanas de gestación constituye el tratamiento estándar de los casos graves de hernia diafragmática congénita (CDH) diagnosticados prenatalmente. Sin embargo, algunos pacientes presentan indicadores prenatales de hipoplasia pulmonar extrema y, a pesar del tratamiento fetoscópico, su tasa de supervivencia es cercana al 0%. Algunos estudios clínicos abogan por una oclusión traqueal en esta...

  1. Efectos en el desarrollo pulmonar de la oclusión traqueal precoz como terapia fetal de la hipoplasia pulmonar en la hernia diafragmática congénita del feto ovino

    OpenAIRE

    Giné Prades, Carles

    2017-01-01

    Introducción: La oclusión traqueal mediante la colocación fetoscópica de un balón endotraqueal a las 26-29 semanas de gestación constituye el tratamiento estándar de los casos graves de hernia diafragmática congénita (CDH) diagnosticados prenatalmente. Sin embargo, algunos pacientes presentan indicadores prenatales de hipoplasia pulmonar extrema y, a pesar del tratamiento fetoscópico, su tasa de supervivencia es cercana al 0%. Algunos estudios clínicos abogan por una oclusión traqueal en ...

  2. Análisis de diez años de registro de malformaciones congénitas en Costa Rica Ten year analysis of the national registry of congenital anomalies in Costa Rica

    OpenAIRE

    María de la Paz Barboza-Argüello; Lila María Umaña-Solís

    2008-01-01

    Justificación y objetivo: Las malformaciones congénitas constituyen la segunda causa de mortalidad infantil en Costa Rica; este estudio se realizó con el objetivo de determinar la prevalencia de nacidos malformados y polimalformados durante 1996-2005, y describir su comportamiento en tiempo, lugar y persona. Métodos: Se consideró malformado simple a todo individuo cuya malformación se hubiera codificado mediante la CIE 10, y polimalformado a los recién nacidos diagnosticados con un síndrome o...

  3. Protocolo de atención a niños y adolescentes con cardiopatía congénita en odontopediatría. Revision bibliográfica

    OpenAIRE

    Juan Manuel de Jesús Cortes de la Torre; Raúl Arturo Cortes de la Torre; Laura Otilia Salazar; Alfredo Salazar de Santiago; Celia Elizabeth Luna Pacheco

    2015-01-01

    Introducción. Las cardiopatías congénitas son las malformaciones más habituales en el desarrollo de los niños los cuales, además, son susceptibles a desarrollar infecciones sistémicas microbianas secundarias a infecciones locales polimicrobianas como consecuencia de procedimientos dentales invasivos o toman fármacos, por ejemplo anti-coagulantes, antiarrítmicos, u otros, que pueden interferir con el manejo odontológico. Objetivo. Proponer un protocolo de manejo odontológico que permita detect...

  4. Prevalencia de malformaciones congénitas en hijos de madres mayores de 34 años y adolescentes: Hospital Clínico de la Universidad de Chile, 2002-2011

    OpenAIRE

    Nazer Herrera,Julio; Cifuentes Ovalle,Lucía

    2013-01-01

    Antecedentes: Las madres mayores de 34 años han aumentado en Chile. La mayor edad materna aumenta el riesgo de malformaciones congénitas (MFC) Objetivos: Determinar la tasa de prevalencia de MFC entre adolescentes y mayores de 34 años. Método: Se utilizó la base de datos de la Maternidad del Hospital Clínico Universidad de Chile (2002-2011). Se estudió todos los nacimientos, vivos, mortinatos y malformados de 500 gramos o más, de madres menores de 20 y mayores de 34 años. Se calculó y comparó...

  5. Relación entre sobrepeso y obesidad materna con cardiopatías congénitas. Estudio retrospectivo caso-control en el área norte de Buenos Aires

    OpenAIRE

    S.M. Benítez; A.C.J. Barreto Paternina; E.A. Duro

    2017-01-01

    Antecedentes: Existen discrepancias sobre la relación sobrepeso/obesidad (S/O) materna pregestacional y cardiopatías congénitas estructurales (CCE). La prevalencia mundial de S/O se ha incrementado en las mujeres en edad reproductiva y esto podría tener efectos sobre los servicios de recién nacidos (RN). Objetivos: Estimar el riesgo de CCE asociadas a S/O materna preconcepcional en nuestra área de trabajo. Material y métodos: Estudio cuantitativo, observacional retrospectivo y analítico...

  6. Uso de pericardio bovino para la corrección de cardiopatías congénitas Use of bovine pericardium for correcting congenital cardiopathies

    Directory of Open Access Journals (Sweden)

    Juan C Rendón

    2007-08-01

    Full Text Available El parche de pericardio bovino se ha utilizado como una alternativa para diferentes patologías quirúrgicas, entre las que se incluyen las malformaciones cardiacas congénitas. Pese a ello, hay pocos artículos que reportan la experiencia con este tipo parche. El objetivo de este estudio es evaluar la experiencia con el uso de pericardio bovino para la reconstrucción de cardiopatías en la Clínica Cardiovascular Santa María, desde 1994. Materiales y métodos: se sometieron 520 pacientes a un procedimiento quirúrgico correctivo o paliativo de alguna cardiopatía congénita en la que se utilizó el parche de pericardio bovino. De éstos, 163 tenían un seguimiento de por lo menos dos años. Se evaluó la localización del parche, el tipo de procedimientos, la supervivencia, las calcificaciones, los aneurismas y las fugas. Así mismo, se evaluó la clase funcional y se comparó la supervivencia de los pacientes de acuerdo con la localización y el tipo de parche. Resultados: se realizaron 520 procedimientos en los cuales se usó el parche de pericardio bovino. Las malformaciones predominantes fueron los defectos septales (58%, seguidos de la tetralogía de Fallot (16%. También se utilizó el parche en conexiones anómalas venosas totales o parciales y atresia pulmonar, entre otros. El 50,9% estaba localizado de manera sistémica y el 49,1% en la circulación pulmonar. De acuerdo con la localización, 50,3% eran intra cardiacos y 49,7% extra cardiacos. En la implantación se reportaron dos fugas, dos sangrados y tres reintervenciones. Durante el seguimiento sólo se reportaron tres fugas. La supervivencia global fue de 95%. No hubo diferencias significativas en la supervivencia de los parches intra o extra cardiacos ni en los que soportaban la circulación sistémica o pulmonar. No se reportaron calcificaciones. El 95% de los pacientes tenían clase funcional I ó II y los restantes III ó IV. Conclusiones: el parche de pericardio bovino es

  7. Fluctuation patterns of groundwater levels in Tokyo caused by the Great East Japan Earthquake

    Science.gov (United States)

    Kawamura, Akira; Ishihara, Shigeyuki; Amaguchi, Hideo; Takasaki, Tadakatsu

    2016-04-01

    The hourly groundwater levels have been observed at 42 sites in Tokyo Metropolis since 1952. The Great East Japan Earthquake occurred at 14:46 JST on March 11, 2011. It was the strongest earthquake on record with a magnitude of 9.0 (Mw) and large fluctuations of unconfined and confined groundwater levels were observed at 102 observation wells in Tokyo, around 400 km away from the epicenter. Abrupt rises and sharp drawdowns of groundwater levels were observed right after the earthquake for most of the wells, although some did not show a change. In this study, taking full advantage of the unique rare case data from the dense groundwater monitoring network in Tokyo, we investigate the fluctuation patterns of unconfined and confined groundwater levels caused by the Great East Japan Earthquake. The groundwater level data used in this study consist of one month time series in March 2011 with one-hour interval. The fluctuation patterns of groundwater levels caused by the earthquake were identified using Self-Organizing Maps (SOM). The SOM, developed by Kohonen, can project high-dimensional, complex target data onto a two-dimensional regularly arranged map in proportion to the degree of properties. In general, the objective of the SOM application is to obtain useful and informative reference vectors. These vectors can be acquired after iterative updates through the training of the SOM. Design of the SOM structure, selection of a proper initialization method, and data transformation methods were carried out in the SOM application process. The reference vectors obtained from the SOM application were fine-tuned using cluster analysis methods. The optimal number of clusters was selected by the Davies-Bouldin index (DBI) using the k-means algorithm. Using the optimal number of cluster, a final fine-tuning cluster analysis was carried out by Ward's method. As a result, the fluctuation patterns of the confined and unconfined groundwater level were classified into eight clusters

  8. Tracing cohesive sediment transportation at river mouths around Tokyo, Japan by Cesium originated from Fukushima Daiichi Power Plant

    Science.gov (United States)

    koibuchi, Y.

    2012-12-01

    Sediment transport at river mouths, which consists of suspended-load and bed-load, has not been fully understood, since bed-load transport of cohesive sand is difficult to observe. Especially, the impact of sediment transport on the total amount of fine-grained cohesive sediment has not been elucidated. Cesium-134 and cesium-137 were spread from the Fukushima Daiichi Nuclear Power Plant (FDNPP) after the earthquake of March 11 of 2011, and attached to the fine-grained sand on the land. The contaminated sand flowed into the river mouths through the rivers possibly due to the complex physical processes in estuarine areas. To evaluate the fine-grained sediment transport around Tokyo and Tokyo Bay, field observations were carried out utilizing radionuclide originated from FDNPP as an effective tracer. The cohesive sediment transport at three different river mouths around Tokyo was successfully quantified. The cohesive sediment transport deposited in the estuary was found to be greatly dependent on the land use, geometry, river discharge and salinity. In addition,the transport driven by the rainfall was minute, and its behavior was quite different from suspended solids. Although further field observations of radionuclide are necessary, it is clear that fine-grained sediment in the bay from rivers already settled on the river mouth by aggregation. The settled sand will not move even in rainfall events. Consequently, the transport of radionuclide to the Pacific Ocean may not occur.; Cesium distribution around Tokyo Bay ; Cesium Concentration in Edogawa river

  9. Estimating Vector-borne Viral Infections in the Urban Setting of the 2020 Tokyo Olympics, Japan, Using Mathematical Modeling.

    Science.gov (United States)

    Furuya, Hiroyuki

    2017-12-20

    The first domestic outbreak of dengue fever in Japan since 1945 was reported in Tokyo in 2014. Meanwhile, daily mean summer temperatures are expected to continue to rise world-wide. Such conditions are expected to increase the risk of an arbovirus outbreak at the 2020 Tokyo Olympic Games. To address this possibility, the present study compared estimates of the risk of infection by dengue, chikungunya, and Zika viruses in urban areas. To compare the risk of infection by arboviruses transmitted by Ae. albopictus mosquitoes, the reproduction number for each of three arboviruses was estimated under the environmental conditions associated with the 2014 dengue outbreak in Tokyo, and additionally under conditions assuming a daily mean temperature elevation of 2° C. For dengue, chikungunya, and Zika, the estimated distributions of R 0 were independently fitted to gamma distributions yielding median R 0 values of 1.00, 0.46, and 0.36, respectively. If the daily mean temperature were to rise from 28° C to 30° C, our model predicts increases of the median R 0 of 18% for dengue, 4.3% for chikungunya, and 11.1% for Zika. Strengthening of the public health responsivity for these emerging arboviral diseases will be needed in preparation for the 2020 Olympic Games in Tokyo.

  10. An application of the node place model to explore the spatial development dynamics of station areas in Tokyo

    NARCIS (Netherlands)

    Chorus, P.; Bertolini, L.

    2011-01-01

    The high level of integration between railway and real estate development in Tokyo makes the city an interesting example for metropolitan areas looking for ways to promote transit-oriented development. To successfully promote such a development pattern, an understanding of development dynamics in

  11. Comparison study on observed and estimated concentrations of perfluorooctane sulfonate using a fate model in Tokyo Bay of Japan.

    Science.gov (United States)

    Miyake, Yuichi; Kobayashi, Takeshi; Kameya, Takashi; Managaki, Satoshi; Amagai, Takashi; Masunaga, Shigeki

    2014-01-01

    Perfluorooctane sulfonate (PFOS) was quantified in seawater and sediment samples collected from Tokyo Bay, Japan, ranging from 2.0 to 7.3 ng/L for surface seawater, 2.2 to 5.7 ng/L for intermediate seawater, 1.5 to 5.7 ng/L for bottom seawater, and 0.3 to 0.9 ng/g dry wt. for sediment. In addition, a 3-D chemical fate prediction model (National Institute of Advanced Industrial Science and Technology - Risk Assessment Model: AIST-RAM) has been applied to determine the accuracy of estimating PFOS in Tokyo Bay. A decreasing trend of PFOS from the northwestern part (i.e., the closed-off section of Tokyo Bay) to the mouth of the bay was observed, and the trend obtained from the actual surveys in this study was accurately represented by simulation with appropriate input parameters for AIST-RAM. From the comparison of observed concentrations with estimated concentrations, AIST-RAM showed a high degree of accuracy in estimating the concentrations of PFOS in seawater, whereas the estimations of PFOS concentrations in sediment had a relatively larger margin of error than those in seawater. However, our results indicate that AIST-RAM allows estimation of PFOS concentrations in seawater and sediment in Tokyo Bay with satisfactory accuracy.

  12. Tokyo Guidelines 2018: surgical management of acute cholecystitis: safe steps in laparoscopic cholecystectomy for acute cholecystitis (with videos)

    NARCIS (Netherlands)

    Wakabayashi, Go; Iwashita, Yukio; Hibi, Taizo; Takada, Tadahiro; Strasberg, Steven M.; Asbun, Horacio J.; Endo, Itaru; Umezawa, Akiko; Asai, Koji; Suzuki, Kenji; Mori, Yasuhisa; Okamoto, Kohji; Pitt, Henry A.; Han, Ho-Seong; Hwang, Tsann-Long; Yoon, Yoo-Seok; Yoon, Dong-Sup; Choi, In-Seok; Huang, Wayne Shih-Wei; Giménez, Mariano Eduardo; Garden, O. James; Gouma, Dirk J.; Belli, Giulio; Dervenis, Christos; Jagannath, Palepu; Chan, Angus C. W.; Lau, Wan Yee; Liu, Keng-Hao; Su, Cheng-Hsi; Misawa, Takeyuki; Nakamura, Masafumi; Horiguchi, Akihiko; Tagaya, Nobumi; Fujioka, Shuichi; Higuchi, Ryota; Shikata, Satoru; Noguchi, Yoshinori; Ukai, Tomohiko; Yokoe, Masamichi; Cherqui, Daniel; Honda, Goro; Sugioka, Atsushi; de Santibañes, Eduardo; Supe, Avinash Nivritti; Tokumura, Hiromi; Kimura, Taizo; Yoshida, Masahiro; Mayumi, Toshihiko; Kitano, Seigo; Inomata, Masafumi; Hirata, Koichi; Sumiyama, Yoshinobu; Inui, Kazuo; Yamamoto, Masakazu

    2018-01-01

    In some cases, laparoscopic cholecystectomy (LC) may be difficult to perform in patients with acute cholecystitis (AC) with severe inflammation and fibrosis. The Tokyo Guidelines 2018 (TG18) expand the indications for LC under difficult conditions for each level of severity of AC. As a result of

  13. Distribution and sources of polycyclic aromatic hydrocarbons (PAHs) in street dust from the Tokyo Metropolitan area.

    Science.gov (United States)

    Takada, H; Onda, T; Harada, M; Ogura, N

    1991-09-01

    Molecular distributions of polycyclic aromatic hydrocarbons (PAHs) in street dust samples collected from the Tokyo Metropolitan area were determined by capillary gas chromatography following HPLC fractionation. Three- to six-ring PAHs and sulfur-heterocyclics were detected. PAHs in the dusts were dominated by three and four unsubstituted ring systems with significant amounts of their alkyl homologues. PAHs were widely distributed in the streets, with concentrations (sigma COMB) of a few microgram/g dust. Automobile exhaust, asphalt, gasoline fuel, diesel fuel, tyre particles, automobile crankcase oils, and atmospheric fallout were also analysed. The PAH profile, especially the relative abundance of alkyl-PAHs and sulfur-containing heterocyclics, indicated that PAHs in the street dusts from roads carrying heavy traffic are mainly derived from automobile exhausts; dusts from residential areas have a more significant contribution from atmospheric fallout.

  14. Corrosion resistance of Al roof in the residential area of Tokyo

    Energy Technology Data Exchange (ETDEWEB)

    Morisaki, S. [Tokyo Metropolitan Univ., Tokyo (Japan). Faculty of Science; Nagase, H. [Tokyo Metropolitan Univ., Tokyo (Japan). Faculty of Technology; Tanizaki, Y. [Tokyo Metropolitan Isotope Research Center, Tokyo (Japan)

    1995-01-05

    The most significant method for assessing the corrosion of Al is that for the evaluation of its durability, based on corrosion tests in natural environments. The results of a few atmospheric exposure tests of Al and its alloys in various environments were reported. The results of laboratory accelerated tests and the above results did not give a good correlation for the evaluation of corrosion, because it is difficult to reproduce a number of atmospheric corrosive agents (humidity, rainfall, sunlight, winds, exhaust gases, natural gas, dust and so on) in a laboratory. In this report, the commercial pure Al roof (1050) of a private wooden house exposed for 28 years in the residential area of Tokyo, 10 km away from seashore, was analyzed. Pits formed on the pure Al roof (1050) did not propagate and penetrate vertically. Therefor, the Al roof as rolled without any pretreatments showed an excellent protection against weathering for a long period of time. 7 refs., 2 figs., 1 tab.

  15. Design of Tokyo Tech nano-satellite Cute-1.7+APD II and its operation

    Science.gov (United States)

    Ashida, Hiroki; Fujihashi, Kota; Inagawa, Shinichi; Miura, Yoshiyuki; Omagari, Kuniyuki; Miyashita, Naoki; Matunaga, Saburo; Toizumi, Takahiro; Kataoka, Jun; Kawai, Nobuyuki

    2010-05-01

    Cute-1.7+APD II is the 3rd satellite developed by the Laboratory for Space Systems at the Tokyo Institute of Technology. Cute-1.7+APD II is the current successor to Cute-1.7+APD. This new satellite is based on its predecessor but has some modifications to increase its reliability and robustness against radiation effects, electrical power shortage and so on. The satellite was launched by an ISRO PSLV-C9 rocket on April 28, 2008 and has operated for more than 9 months. Throughout its operation, many missions such as attitude determination and control experiments, scientific observations, photographing and communication experiments have been conducted. In this paper an overview of the Cute-1.7 series and configurations, modifications and operation results of Cute-1.7+APD II are introduced.

  16. Tokyo et les campagnes: la progression de la banlieue à Toride

    Directory of Open Access Journals (Sweden)

    Henri Desbois

    1999-09-01

    Full Text Available L'espace périurbain japonais se distingue de ce que l'on observe en Europe ou aux États-Unis. La ville progresse en conservant dans son tissu même des éléments agro-ruraux. Nous utilisons ici un SIG réalisé pour deux quartiers de la commune de Toride, située dans la lointaine banlieue de Tokyo ; il permet de quantifier l'extension urbaine et de mieux en saisir le rythme depuis 1945. Il permet aussi de mettre en évidence le paysage très bigarré et, à certains égards, désordonné des grandes banlieues japonaises contemporaines.

  17. Classification of magnitude 7 earthquakes which occurred after 1885 in Tokyo Metropolitan area

    Science.gov (United States)

    Ishibe, T.; Satake, K.; Shimazaki, K.; Nishiyama, A.

    2010-12-01

    Tokyo Metropolitan area is situated in tectonically complex region; both the Pacific (PAC) and Philippine Sea (PHS) plates are subducting from east and south, respectively, beneath the Kanto region. As a result, various types of earthquakes occur in this region; i.e., shallow crustal earthquakes, intraplate (slab) earthquakes within PHS, within PAC, and interplate earthquakes between continental plate and PHS, and between PHS and PAC. Among these, the largest earthquakes are Kanto earthquakes (M~8) occurring between the continental plate and PHS. The average recurrence interval is estimated to be 200 - 400 years (Earthq. Res. Comm., 2004), and hence, urgency of the next Kanto earthquake is thought to be low considering the lapse time (~87 yrs.) from the most recent Kanto earthquake in 1923. However, urgency of the other types of earthquakes with M~7 is high; Earthq. Res. Comm. (2004) calculated the probability of occurrence during the next 30 years as 70 %, based on the facts that five M~7 earthquakes (i.e., the 1894 Meiji-Tokyo, 1895 and 1921 Ibaraki-Ken-Nanbu, 1922 Uraga channel and 1987 Chiba-Ken Toho-Oki earthquakes) occurred since 1885. However, types of earthquakes are not well known especially for the 1894 Meiji-Tokyo and 1895 Ibaragi-Ken-Nanbu earthquakes due to low quality of data. Thus, it is important to classify these earthquakes into above-described intraplate or interplate earthquakes and to estimate their occurrence frequency. Ishibe et al. (2009a, 2009b) compiled previous studies and data for these five earthquakes. In this study, we report the preliminary result of focal depth and mechanism for the 1895 and 1921 Ibaraki-Ken-Nanbu earthquakes. The epicenter of the 1895 Ibaraki-Ken-Nanbu earthquake (M 7.2; Utsu, 1979) is discussed by various studies (e.g., Usami, 1973; Ishibashi, 1975; Katsumata, 1975; Utsu, 1979). However, few studies have discussed the hypocentral depth. The hypocentral depth is estimated to be 75 ~ 85 km using S-P time at Tokyo

  18. Perfluorinated surfactants (PFSs) in size-fractionated street dust in Tokyo.

    Science.gov (United States)

    Murakami, Michio; Takada, Hideshige

    2008-11-01

    We investigated perfluorinated surfactants (PFSs) in size-fractionated street dust to identify their occurrence, contributions from traffic, and potential routes of entry into waters. Street dust was collected from residential areas and heavily trafficked areas in Tokyo and sorted into fine (fine fractions, PFS contents were significantly higher in heavily trafficked street dust than in residential street dust, but in coarse fractions, no significant differences were observed. Additionally, in heavily trafficked areas, PFS contents were significantly higher in fine fractions than in coarse fractions, but in residential areas, no significant differences were observed. PFS compositions differed between size fractions, not locations, indicating differences in sources between size fractions. Fine particles from traffic contributed to PFSs in street dust. Street dust possibly acts as the origin of PFSs in street runoff and eventually enters waters. This is the first report of PFSs in street dust.

  19. Application of a mathematical model to predict dioxin concentrations in the Tokyo Bay estuary

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, N.; Horiguchi, F.; Nakanishi, J. [National Inst. of Advanced Industrial Science and Tech., Tsukuba (Japan); Nakata, K. [Tokai Univ., Shizuoka (Japan); Eriguchi, T. [Chuden CTI Co., Ltd., Nagoya (Japan); Masunaga, S. [Yokohama National Univ., Yokohama (Japan)

    2004-09-15

    In order to assess the ecological risk posed by dioxins in the environment, information regarding the distribution of dioxin concentration under long term monitoring and over a wide area is necessary. However, it is almost impossible to obtain such data because dioxin analysis needs considerable time and effort. Thus, mathematical models that can predict dioxin concentrations in the environment are required. Especially in Japan, where main pathway of human exposure to dioxins is through consumption of fish and shellfish, investigation of aquatic environment is very important. However, data on these environmental mediums, such as river, bay, and inner sea, are very limited. In this study, a 3-D chemical fate prediction model was developed and applied to the Tokyo Bay estuary to predict distributions and variations of polychlorinated dibenzop- dioxins, dibenzofurans (PCDD/Fs), and dioxin-like PCBs in the seawater of the estuary.

  20. Improvement of the High Fluence Irradiation Facility at the University of Tokyo

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Kenta, E-mail: murakami@tokai.t.u-tokyo.ac.jp [Nuclear Professional School, School of Engineering, The University of Tokyo, 2-22 Shirakata-Shirane, Tokai-mura, Ibaraki 319-1188 (Japan); Iwai, Takeo, E-mail: iwai@med.id.yamagata-u.ac.jp [Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata, Yamagata-shi 990-9585 (Japan); Abe, Hiroaki, E-mail: abe.hiroaki@n.t.u-tokyo.ac.jp [Nuclear Professional School, School of Engineering, The University of Tokyo, 2-22 Shirakata-Shirane, Tokai-mura, Ibaraki 319-1188 (Japan); Sekimura, Naoto, E-mail: sekimura@n.t.u-tokyo.ac.jp [Department of Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1, Tokyo, Hongo, Bunkyo, 113-8656 (Japan)

    2016-08-15

    This paper reports the modification of the High Fluence Irradiation Facility at the University of Tokyo (HIT). The HIT facility was severely damaged during the 2011 earthquake, which occurred off the Pacific coast of Tohoku. A damaged 1.0 MV tandem Cockcroft-Walton accelerator was replaced with a 1.7 MV accelerator, which was formerly used in another campus of the university. A decision was made to maintain dual-beam irradiation capability by repairing the 3.75 MV single-ended Van de Graaff accelerator and reconstructing the related beamlines. A new beamline was connected with a 200 kV transmission electron microscope (TEM) to perform in-situ TEM observation under ion irradiation.

  1. Creating the 2020 Tokyo Olympic Medals from Electronic Scrap: Sustainability Analysis

    Science.gov (United States)

    Leader, Alexandra M.; Wang, Xue; Gaustad, Gabrielle

    2017-09-01

    For the upcoming 2020 Olympic Games, which are to be held in Tokyo, Japan, it has been proposed that recycled metal from electronic waste should be used to create the gold, silver, and bronze medals that will be awarded to athletes from around the world. This work is aimed at exploring the feasibility of this goal, quantifying the required electronic waste, identifying the limiting material constraints, and addressing a selection of sustainability metrics. The results show that 2.5-13.8% of Japan's available electronic waste would be required to create the medals, depending on the composition of the collected electronics and the processing yields. The environmental benefits from this venture are identified as being a savings of approximately 4.5-5.1 TJ of energy, which is equivalent to CO2 emissions reductions of approximately 420 metric tons. Additionally, qualitative potential benefits to environment, human health, economic recovery of valuable materials, and supply stability are considered.

  2. Annual report of Nuclear Engineering Research Laboratory, University of Tokyo in fiscal 1992

    International Nuclear Information System (INIS)

    1993-07-01

    In this annual report, the activities of education and research, the state of operation of research facilities and others in Nuclear Engineering Research Laboratory, University of Tokyo in fiscal year 1992 are summarized. In this Laboratory, there are four large research facilities, that are, the fast neutron source reactor 'Yayoi', the electron beam linac, the nuclear fusion reactor blanket experiment facility and the heavy irradiation research facility. Those are used for carrying out education and research in the wide fields of nuclear engineering, and are offered also for joint utilization. The results of research by using respective research facilities have been summarized in separate reports. The course of the management and operation of each research facility is described, and the research activities, the theses for doctorate and graduation these of teachers, personnel and graduate students in the Laboratory are summarized. (J.P.N.)

  3. Annual report of Nuclear Engineering Research Laboratory, University of Tokyo in fiscal 1993

    International Nuclear Information System (INIS)

    1994-08-01

    In this annual report, the activities of research and education, the state of operation of research facilities and others in fiscal year 1993 are summarized. Four main research facilities are the fast neutron source reactor 'Yayoi', the electron linear accelerator, the basic experiment facility for nuclear fusion reactor blanket design and the heavy irradiation research facility. The reactor and the accelerator are for the joint utilization by all universities in Japan, the blanket is used by the Faculty of Engineering, and the HIT is for the joint utilization in University of Tokyo. In fiscal year 1993, the installation of the fast neutron science research facility was approved. In this annual report, the management and operation of the above research facilities are described, and the research activities, the theses for doctorate and graduation theses of teachers, are summarized. (K.I.)

  4. Analisis Kinerja Kontrak Berjangka Komoditi pada Tokyo Grain Exchange – Jepang

    Directory of Open Access Journals (Sweden)

    Tomy G. Soemapradja

    2005-03-01

    Full Text Available Futures contract is one of derivative instruments in which its value depends on underlying asset’s price fluctuation in the future. At the beginning, the futures contracts were traded with hedging motive, but now they are traded with speculative motive also. As an agricultural nation, finally, Indonesia has a commodity futures exchange (BBJ by the end of 2000. Low volume of transactions and less futures alternative on BBJ made Tokyo Grain Exchange (TGE as the object of this research. The statistical test concluded: The average rate of return of futures portfolio model is greater than average of forex trading of USD, and the risk of futures portfolio model is greater than forex trading of USD.

  5. RESEARCH INTO PSYCHOLOGICAL EVALUATION METHOD OF UNDERGROUND SPACE - CENTERING ON THE TOKYO METRO -

    Science.gov (United States)

    Yoshimoto, Naomi; Wake, Tenji; Mita, Takeshi; Wake, Hiromi

    This research is concerned with developing evaluation methods that can be useful for environmental design from the psychological perspective of QOL, that is comfort, in underground space. For this research, eight stations on the Tokyo Metro, including the Fukutoshin line, were selected and two types of questionnaires were carried out after respondents had walked through the station areas and the walkways connecting the stations. From the results of the first questionnaire, four factors, comfort/convenience, insecurity, visibility/noticeability, brightness/ease of walking, were extracted. From the results of the second questionnaire, three factors were extracted: visibility of noticeboards, overall atmosphere of underground space, visibility of fare chart/subway map. There was a strong correlation between the factors comfort/convenience and insecurity, extracted from the first questionnaire, and the overall atmosphere factor extracted from the second questionnaire. For visibility/noticeability, there was a strong correlation with notices, fares chart, and subway map.

  6. The Tokyo subway sarin attack: disaster management, Part 2: Hospital response.

    Science.gov (United States)

    Okumura, T; Suzuki, K; Fukuda, A; Kohama, A; Takasu, N; Ishimatsu, S; Hinohara, S

    1998-06-01

    The Tokyo subway sarin attack was the second documented incident of nerve gas poisoning in Japan. The authors report how St. Luke's Hospital dealt with this disaster from the viewpoint of disaster management. Recommendations derived from the experience include the following: Each hospital in Japan should prepare an emergent decontamination area and have available chemical-resistant suits and masks. Ventilation in the ED and main treatment areas should be well planned at the time a hospital is designed. Hospital disaster planning must include guidance in mass casualties, an emergency staff call-up system, and an efficient emergency medical chart system. Hospitals should establish an information network during routine practice so that it can be called upon at the time of a disaster. The long-term effects of sarin should be monitored, with such investigation ideally organized and integrated by the Japanese government.

  7. Definitive evidence for the acute sarin poisoning diagnosis in the Tokyo subway.

    Science.gov (United States)

    Nagao, M; Takatori, T; Matsuda, Y; Nakajima, M; Iwase, H; Iwadate, K

    1997-05-01

    A new method was developed to detect sarin hydrolysis products from erythrocytes of four victims of sarin (isopropylmethylphosphonofluoridate) poisoning resulting from the terrorist attack on the Tokyo subway. Sarin-bound acetylcholinesterase (AChE) was solubilized from erythrocyte membranes of sarin victims, digested with trypsin, the sarin hydrolysis products bound to AChE were released by alkaline phosphatase digestion, and the digested sarin hydrolysis products were subjected to trimethylsilyl derivatization and detected by gas chromatography-mass spectrometry. Isopropylmethylphosphonic acid, which is a sarin hydrolysis product, was detected in all sarin poisoning, victims we examined and methylphosphonic acid, which is a sarin and soman hydrolysis product, was determined in all victims. Postmortem examinations revealed no macroscopic and microscopic findings specific to sarin poisoning and sarin and its hydrolysis products were almost undetectable in their blood. We think that the procedure described below will be useful for the forensic diagnosis of acute sarin poisoning.

  8. Prevalence of insomnia among residents of Tokyo and osaka after the great East Japan earthquake: a prospective study.

    Science.gov (United States)

    Sugiura, Hiroaki; Akahane, Manabu; Ohkusa, Yasushi; Okabe, Nobuhiko; Sano, Tomomi; Jojima, Noriko; Bando, Harumi; Imamura, Tomoaki

    2013-01-18

    The Great East Japan Earthquake occurred on March 11, 2011. Tokyo and Osaka, which are located 375 km and 750 km, respectively, from the epicenter, experienced tremors of 5.0 lower and 3.0 seismic intensity on the Japan Meteorological Agency scale. The Great East Japan Earthquake was the fourth largest earthquake in the world and was accompanied by a radioactive leak at a nuclear power plant and a tsunami. In the aftermath of a disaster, some affected individuals presented to mental health facilities with acute stress disorder (ASD) and/or post-traumatic stress disorder (PTSD). However, few studies have addressed mental stress problems other than ASD or PTSD among the general public immediately after a disaster. Further, the effects of such a disaster on residents living at considerable distances from the most severely affected area have not been examined. This study aimed to prospectively analyze the effect of a major earthquake on the prevalence of insomnia among residents of Tokyo and Osaka. A prospective online questionnaire study was conducted in Tokyo and Osaka from January 20 to April 30, 2011. An Internet-based questionnaire, intended to be completed daily for a period of 101 days, was used to collect the data. All of the study participants lived in Tokyo or Osaka and were Consumers' Co-operative Union (CO-OP) members who used an Internet-based food-ordering system. The presence or absence of insomnia was determined before and after the earthquake. These data were compared after stratification for the region and participants' age. Multivariate analyses were conducted using logistic regression and a generalized estimating equation. This study was conducted with the assistance of the Japanese CO-OP. The prevalence of insomnia among adults and minors in Tokyo and adults in Osaka increased significantly after the earthquake. No such increase was observed among minors in Osaka. The overall adjusted odds ratios for the risk of insomnia post-earthquake versus pre

  9. Sensitivity analyses of OH missing sinks over Tokyo metropolitan area in the summer of 2007

    Directory of Open Access Journals (Sweden)

    K. Ishii

    2009-11-01

    Full Text Available OH reactivity is one of key indicators which reflect impacts of photochemical reactions in the atmosphere. An observation campaign has been conducted in the summer of 2007 at the heart of Tokyo metropolitan area to measure OH reactivity. The total OH reactivity measured directly by the laser-induced pump and probe technique was higher than the sum of the OH reactivity calculated from concentrations and reaction rate coefficients of individual species measured in this campaign. And then, three-dimensional air quality simulation has been conducted to evaluate the simulation performance on the total OH reactivity including "missing sinks", which correspond to the difference between the measured and calculated total OH reactivity. The simulated OH reactivity is significantly underestimated because the OH reactivity of volatile organic compounds (VOCs and missing sinks are underestimated. When scaling factors are applied to input emissions and boundary concentrations, a good agreement is observed between the simulated and measured concentrations of VOCs. However, the simulated OH reactivity of missing sinks is still underestimated. Therefore, impacts of unidentified missing sinks are investigated through sensitivity analyses. In the cases that unknown secondary products are assumed to account for unidentified missing sinks, they tend to suppress formation of secondary aerosol components and enhance formation of ozone. In the cases that unidentified primary emitted species are assumed to account for unidentified missing sinks, a variety of impacts may be observed, which could serve as precursors of secondary organic aerosols (SOA and significantly increase SOA formation. Missing sinks are considered to play an important role in the atmosphere over Tokyo metropolitan area.

  10. Changes in the first line Helicobacter pylori eradication rates using the triple therapy-a multicenter study in the Tokyo metropolitan area (Tokyo Helicobacter pylori study group).

    Science.gov (United States)

    Kawai, Takashi; Takahashi, Shin'ichi; Suzuki, Hidekazu; Sasaki, Hitoshi; Nagahara, Akihito; Asaoka, Daisuke; Matsuhisa, Takeshi; Masaoaka, Tatsuhiro; Nishizawa, Toshihiro; Suzuki, Masayuki; Ito, Masayoshi; Kurihara, Naoto; Omata, Fumio; Mizuno, Shigeaki; Torii, Akira; Kawakami, Kohei; Ohkusa, Toshifumi; Tokunaga, Kengo; Mine, Tetsuya; Sakaki, Nobuhiro

    2014-12-01

    Helicobacter pylori (H. pylori) infection is a strong risk factor for the development of gastric cancer. In 2013, the Japanese government approved H. pylori eradication therapy in patients with chronic gastritis as well as peptic ulcer. However, the continuing decline in eradication rates for first-line H. pylori eradication therapies is an urgent problem. In this study, we investigated changes in the first-line eradication rate from 2001 to 2010. Eradication rates for 7-day triple therapy [proton pump inhibitor (rabeprazole 20 mg, lansoprazole 60 mg, or omeprazole 40 mg)+amoxicillin 1500 mg + clarithromycin (CAM) 400 or 800 mg, daily] were collated from 14 hospitals in the Tokyo metropolitan area. The urea breath test was used for the evaluation of eradication. The cut-off value was less than 2.5%. The yearly eradication rates (intention to treat/per protocol) were 78.5/79.5% (2001, n=242), 71.2%/72.9% (2002, n=208), 67.8%/70.5% (2003, n=183), 75.6%/84.6% (2004, n=131), 56.4%/70.5% (2005, n=114), 70.5%/75.8% (2006, n=271), 67.4%/82.0% (2007, n=135), 64.0%/76.3% (2008, n=261), 60.5%/74.3% (2009, n=329), and 66.5%/78.8% (2010, n=370), respectively. Examination of eradication rates according to CAM dosage revealed an eradication rate of 65.6% (383/584) for CAM 400 mg daily, and 68.5% (1124/1642) for CAM 800 mg daily, with no significant difference seen between dosages. In recent years, eradication rates for first-line triple therapy have obviously decreased, but no noticeable decrease has occurred after 2001. © 2014 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

  11. Current characteristics and management of ST elevation and non-ST elevation myocardial infarction in the Tokyo metropolitan area: from the Tokyo CCU network registered cohort.

    Science.gov (United States)

    Miyachi, Hideki; Takagi, Atsushi; Miyauchi, Katsumi; Yamasaki, Masao; Tanaka, Hiroyuki; Yoshikawa, Masatomo; Saji, Mike; Suzuki, Makoto; Yamamoto, Takeshi; Shimizu, Wataru; Nagao, Ken; Takayama, Morimasa

    2016-11-01

    Limited data exists on ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) managed by a well-organized cardiac care network in a metropolitan area. We analyzed the Tokyo CCU network database in 2009-2010. Of 4329 acute myocardial infarction (AMI) patients including STEMI (n = 3202) and NSTEMI (n = 1127), percutaneous coronary intervention (PCI) was performed in 88.8 % of STEMI and 70.4 % of NSTEMI patients. Mean onset-to-door and door-to-balloon times in STEMI patients were shorter than those in NSTEMI patients (167 vs 233 and 60 vs 145 min, respectively, p < 0.001). Coronary artery bypass graft surgery was performed in 4.2 % of STEMI and 11.4 % of NSTEMI patients. In-hospital mortality was significantly higher in STEMI patients than NSTEMI patients (7.7 vs 5.1 %, p < 0.007). Independent correlates of in-hospital mortality were advanced age, low blood pressure, and high Killip classification, statin-treated dyslipidemia and PCI within 24 h were favorable predictors for STEMI. High Killip classification, high heart rate, and hemodialysis were significant predictors of in-hospital mortality, whereas statin-treated dyslipidemia was the only favorable predictor for NSTEMI. In conclusion, patients with MI received PCI frequently (83.5 %) and promptly (door-to-balloon time; 66 min), and had favorable in-hospital prognosis (in-hospital mortality; 7.0 %). In addition to traditional predictors of in-hospital death, statin-treated dyslipidemia was a favorable predictor of in-hospital mortality for STEMI and NSTEMI patients, whereas hemodialysis was the strongest predictor for NSTEMI patients.

  12. Filmifestival viib vaataja maailma eri nurkadesse / Kerttu Jänese

    Index Scriptorium Estoniae

    Jänese, Kerttu, 1981-

    2008-01-01

    V festivali "Maailmafilm", mis algab 24. märtsil Eesti Rahva Muuseumi näitusemajas Tartus, tutvustab selle tegevjuht Taavi Tatsi. Filmidest : esilinastuvad Meelis Muhu "Aljosha" ja Liivo Niglase, Diane Perlovi ja Frode Storaasi "Kalarahvas". Kavas on ka kolm eriprogrammi: kirjanikud filmis, klassiku Timothy Aschi looming ja 8 filmi inimesest linnas

  13. Veneetsia filmifestival ilmutas auhindu jagades tolerantsi / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2005-01-01

    62. Veneetsia filmifestivali auhinnasaajad. Parima filmi Kuldlõvi sai Ang Lee "Brokebacki mägi", žürii eripreemia Abel Ferrara (artiklis "Ferrera") "Mary", parimaks naisnäitlejaks tituleeriti Giovanna Mezzogiorno, Marcello Mastroianni nimelise noore näitleja preemia sai Menothy Cesar

  14. Filmifestival õpetas ise filme looma / Aarne Mäe

    Index Scriptorium Estoniae

    Mäe, Aarne, 1967-

    1999-01-01

    30. sept. - 3. okt. Rakvere Exclusiveì ööklubis toimunud Põhjamaade ja Baltikumi noorte videofilmide filmifestivali "Visions of Light" raames tegutsesid ka töötoad : Eesti nukufilmi töötuba ja "Video netis"

  15. Kodumaiselt rahvusvaheline filmifestival. 6. Sleepwalkers' tudengifilmide festival / Katrin Rajasaare

    Index Scriptorium Estoniae

    Rajasaare, Katrin

    2006-01-01

    IX Pimedate Ööde Filmifestivali alafestivali Sleepwalkers' Student Film Festivali tudengifilmidest : eesti filmid ja auhinnatud filmid - peaauhind rootslase Axel Danielsoni "Suvepilved" ("Sommarlek"), eriauhinnad eestlase Ekke Vasli "Nagu ikka", Saksamaa austraallase Jack Rothi "Olli", korealase Chansoo Kimi "Vaudeville"

  16. Filmifestival Berlinale algas madala lennuga / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2009-01-01

    Berliini 59. rahvusvahelisel filmifestivalil nähtud filmidest : Annette K. Oleseni "Väike sõdur" ("Lille soldat"), Stephen Daldry "Ettelugeja" ("The Reader") Bernhard Schlinki romaani alusel, Francois Ozoni "Ricky"

  17. Läti suurim filmifestival lõppes / J. R.

    Index Scriptorium Estoniae

    J. R.

    2008-01-01

    Tänavuse Riia filmifestivali Arsenals auhinnatud filmidest. Eesti filmide edu : Balti võistlusprogrammis oli parim mängufilm "Sügisball", parim dokfilm "Vastutuulesaal" ja publikupreemia ning ühe oikumeenilise žürii preemia sai "Klass". Peaauhinna võitis loosiga ameerika film "Chop Shop" (režii Ramin Bahrani), parimaks animafilmiks tunnistati lätlase Edmunds Jansonsi "Väikese linnu päevik". Debüüdiauhinna sai läti "Monotony" (Juris Poskus) ja FIPRESCI auhinna prantslase Alain Gomis' "Andalusia" ning läti "Vogelfrei"

  18. Pärnu filmifestival õitses, meeri õnnistusetagi / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2007-01-01

    Lõppes XXI Pärnu rahvusvahelise dokumentaal- ja antropoloogiafilmide festival. Sellest, mis sel korral teisiti oli ehk Pärnu linnapea kõrvalejäämine auhinnatseremoonialt. Parima filmi grand prix läks režissöör Wojciech Kasperski filmile "Seemned". Parim visuaalantropoloogiline film oli "Hobusemees". Režissöörid Tell Johansson ja Peter Gerdehag. Lisatud Pärnu festivali preemiaid

  19. Estudio cooperativo de la mortalidad operatoria en la corrección de cardiopatías congénitas en Colombia Cooperative study of operatory mortality in the correction of congenital cardiopaties in Colombia

    Directory of Open Access Journals (Sweden)

    Juan F Vélez M

    2005-04-01

    Full Text Available No se cuenta con información estadística veraz acerca de los resultados del tratamiento de las cardiopatías congénitas en Colombia; por esta razón se diseñó este estudio en el cual se reúne la información sobre mortalidad en cuatro grandes centros cardiovasculares del país, se tiene en cuenta la estratificación del riesgo de mortalidad y se obtienen valores promedio de las diferentes categorías establecidas por el PCCC (Pediatric Cardiac Care Consortium. Estos valores pueden servir como parámetro para la evaluación de los centros que realizan correcciones de cardiopatías congénitas en Colombia.There is no truthful statistical information in regard to the results of congenital malformation treatment in Colombia. For this reason, this study was designed in order to collect information with regard to the mortality in 4 big cardiovascular centers in the country, taking into account the mortality risk stratification and obtaining the mean values of the different categories established by the PCCC (Pediatric Cardiac Care Consortium. The values obtained may be used as a parameter to evaluate the centers that perform corrective surgery of congenital cardiopaties in Colombia.

  20. Accuracy of the Tokyo Guidelines for the diagnosis of acute cholangitis and cholecystitis taking into consideration the clinical practice pattern in Japan.

    Science.gov (United States)

    Yokoe, Masamichi; Takada, Tadahiro; Mayumi, Toshihiko; Yoshida, Masahiro; Hasegawa, Hiroshi; Norimizu, Shinji; Hayashi, Katsumi; Umemura, Shuichiro; Orito, Etsuro

    2011-03-01

    Three years have passed since the publication of the Tokyo Guidelines for the management of acute cholangitis and cholecystitis, and we believe that the time has come to assess their validity. In this study, we validated the diagnostic accuracy of these criteria in 74 patients with an initial diagnosis of acute cholangitis and 81 patients with an initial diagnosis of acute cholecystitis. We also statistically compared the accuracy of the diagnosis made based on the Tokyo Guidelines with that based on the presence of Charcot's triad for acute cholangitis and Murphy's sign for acute cholecystitis with use of the sign test to assess differences. The results revealed that the diagnostic sensitivity and specificity of the Tokyo Guidelines for suspected or definitive acute cholangitis were 72.1 and 38.5%, respectively, and the corresponding values for definitive cholangitis alone were 63.9 and 69.2%, respectively. For definitive acute cholecystitis, the diagnostic sensitivity and specificity of the Tokyo Guidelines were 84.9 and 50.0%, respectively. The accuracy of diagnosis based on the Tokyo Guidelines was significantly higher than that based on the presence of Charcot's triad (acute cholangitis, p Tokyo Guidelines should be used more widely for the diagnosis of acute cholangitis and cholecystitis in the twenty-first century. Hereafter, various efforts should be made to improve the sensitivity and specificity of the diagnostic criterion of the Tokyo Guidelines.

  1. Radioactive contamination in the Tokyo metropolitan area in the early stage of the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident and its fluctuation over five years.

    Science.gov (United States)

    Ishida, Masanobu; Yamazaki, Hideo

    2017-01-01

    Radioactive contamination in the Tokyo metropolitan area in the immediate aftermath of the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident was analyzed via surface soil sampled during a two-month period after the accident. 131I, 134Cs, and 137Cs were detected in these soil samples. The activity and inventory of radioactive material in the eastern part of Tokyo tended to be high. The 134Cs/137Cs activity ratio in soil was 0.978 ± 0.053. The 131I/137Cs ratio fluctuated widely, and was 19.7 ± 9.0 (weighted average 18.71 ± 0.13, n = 14) in the Tokyo metropolitan area. The radioactive plume with high 131I activity spread into the Tokyo metropolitan area and was higher than the weighted average of 6.07 ± 0.04 (n = 26) in other areas. The radiocesium activity and inventory surveyed in soil from a garden in Chiyoda Ward in the center of Tokyo, fell approximately 85% in the four months after the accident, and subsequently tended to rise slightly while fluctuating widely. It is possible that migration and redistribution of radiocesium occurred. The behavior of radiocesium in Tokyo was analyzed via monitoring of radiocesium in sludge incineration ash. The radiocesium activity in the incineration ash was high at wastewater treatment centers that had catchment areas in eastern Tokyo and low at those with catchment areas in western Tokyo. Similar to the case of the garden soil, even in incineration ash, the radiocesium activity dropped rapidly immediately after the accident. The radiocesium activity in the incineration ash fell steadily from the tenth month after the accident until December 2016, and its half-life was about 500 days. According to frequency analysis, in central Tokyo, the cycles of fluctuation of radiocesium activity in incineration ash and rainfall conformed, clearly showing that radiocesium deposited in urban areas was resuspended and transported by rainfall run-off.

  2. Radioactive contamination in the Tokyo metropolitan area in the early stage of the Fukushima Daiichi Nuclear Power Plant (FDNPP accident and its fluctuation over five years.

    Directory of Open Access Journals (Sweden)

    Masanobu Ishida

    Full Text Available Radioactive contamination in the Tokyo metropolitan area in the immediate aftermath of the Fukushima Daiichi Nuclear Power Plant (FDNPP accident was analyzed via surface soil sampled during a two-month period after the accident. 131I, 134Cs, and 137Cs were detected in these soil samples. The activity and inventory of radioactive material in the eastern part of Tokyo tended to be high. The 134Cs/137Cs activity ratio in soil was 0.978 ± 0.053. The 131I/137Cs ratio fluctuated widely, and was 19.7 ± 9.0 (weighted average 18.71 ± 0.13, n = 14 in the Tokyo metropolitan area. The radioactive plume with high 131I activity spread into the Tokyo metropolitan area and was higher than the weighted average of 6.07 ± 0.04 (n = 26 in other areas. The radiocesium activity and inventory surveyed in soil from a garden in Chiyoda Ward in the center of Tokyo, fell approximately 85% in the four months after the accident, and subsequently tended to rise slightly while fluctuating widely. It is possible that migration and redistribution of radiocesium occurred. The behavior of radiocesium in Tokyo was analyzed via monitoring of radiocesium in sludge incineration ash. The radiocesium activity in the incineration ash was high at wastewater treatment centers that had catchment areas in eastern Tokyo and low at those with catchment areas in western Tokyo. Similar to the case of the garden soil, even in incineration ash, the radiocesium activity dropped rapidly immediately after the accident. The radiocesium activity in the incineration ash fell steadily from the tenth month after the accident until December 2016, and its half-life was about 500 days. According to frequency analysis, in central Tokyo, the cycles of fluctuation of radiocesium activity in incineration ash and rainfall conformed, clearly showing that radiocesium deposited in urban areas was resuspended and transported by rainfall run-off.

  3. Clinical features of uveitis in children and adolescents at a tertiary referral centre in Tokyo.

    Science.gov (United States)

    Keino, Hiroshi; Watanabe, Takayo; Taki, Wakako; Nakayama, Makiko; Nakamura, Tomoko; Yan, Kunimasa; Okada, Annabelle A

    2017-04-01

    To analyse clinical features, systemic associations, treatment and visual outcomes of uveitis in children and adolescents at a tertiary centre in Tokyo. Clinical records of 64 patients under the age of 20 years who presented between 2001 and 2013 to the Ocular Inflammation Service of the Kyorin Eye Center, Tokyo were reviewed retrospectively. Of the 64 patients, there was a predominance of girls (70%) and bilateral disease (81%). Mean age at presentation was 12.9 years (4-19 years). Mean follow-up was 46 months (3-144 months). Anterior uveitis was present in 56.3% of patients, panuveitis in 28.1% and posterior uveitis in 15.6%. No patients had intermediate uveitis. The most common diagnostic designation was unclassified uveitis (57.8%). Systemic associations were observed in 10.9% and no patients were diagnosed with juvenile idiopathic arthritis. Ocular complications were observed in 71.9% of patients, including optic disc hyperemia/oedema (40.6%), vitreous opacification (23.4%), posterior synechia (18.7%), increased intraocular pressure (17.1%) and cataract (14.1%). Six patients underwent intraocular surgery, five for cataract extraction and two for glaucoma control. Twelve patients (18.7%) received some form of systemic therapy either corticosteroids, immunosuppressive drugs or biologic agents. The percentage of eyes with a visual acuity of 1.0 or better was 87.1% at baseline, 91.3% at 6 months, 89.6% at 12 months and 87.5% at 36 months. The majority of children and adolescents who presented to us with uveitis had bilateral disease and no systemic disease associations. Only one-fifth of patients required systemic therapy to control their ocular inflammation, and most eyes had a good visual outcome. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  4. Investigating sources and pathways of perfluoroalkyl acids (PFAAs) in aquifers in Tokyo using multiple tracers

    Energy Technology Data Exchange (ETDEWEB)

    Kuroda, Keisuke, E-mail: keisukekr@gmail.com [Department of Urban Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8656 (Japan); Murakami, Michio [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo 153-8505 (Japan); Oguma, Kumiko [Department of Urban Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8656 (Japan); Takada, Hideshige [Laboratory of Organic Geochemistry (LOG), Institute of Symbiotic Science and Technology, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509 (Japan); Takizawa, Satoshi [Department of Urban Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8656 (Japan)

    2014-08-01

    We employed a multi-tracer approach to investigate sources and pathways of perfluoroalkyl acids (PFAAs) in urban groundwater, based on 53 groundwater samples taken from confined aquifers and unconfined aquifers in Tokyo. While the median concentrations of groundwater PFAAs were several ng/L, the maximum concentrations of perfluorooctane sulfonate (PFOS, 990 ng/L), perfluorooctanoate (PFOA, 1800 ng/L) and perfluorononanoate (PFNA, 620 ng/L) in groundwater were several times higher than those of wastewater and street runoff reported in the literature. PFAAs were more frequently detected than sewage tracers (carbamazepine and crotamiton), presumably owing to the higher persistence of PFAAs, the multiple sources of PFAAs beyond sewage (e.g., surface runoff, point sources) and the formation of PFAAs from their precursors. Use of multiple methods of source apportionment including principal component analysis–multiple linear regression (PCA–MLR) and perfluoroalkyl carboxylic acid ratio analysis highlighted sewage and point sources as the primary sources of PFAAs in the most severely polluted groundwater samples, with street runoff being a minor source (44.6% sewage, 45.7% point sources and 9.7% street runoff, by PCA–MLR). Tritium analysis indicated that, while young groundwater (recharged during or after the 1970s, when PFAAs were already in commercial use) in shallow aquifers (< 50 m depth) was naturally highly vulnerable to PFAA pollution, PFAAs were also found in old groundwater (recharged before the 1950s, when PFAAs were not in use) in deep aquifers (50–500 m depth). This study demonstrated the utility of multiple uses of tracers (pharmaceuticals and personal care products; PPCPs, tritium) and source apportionment methods in investigating sources and pathways of PFAAs in multiple aquifer systems. - Highlights: • Aquifers in Tokyo had high levels of perfluoroalkyl acids (up to 1800 ng/L). • PFAAs were more frequently detected than sewage

  5. Seismic activity of Tokyo area and Philippine Sea plate under Japanese Islands

    Science.gov (United States)

    Sakai, S.; Nakagawa, S.; Nanjo, K.; Kasahara, K.; Panayotopoulos, Y.; Tsuruoka, H.; Kurashimo, E.; Obara, K.; Hirata, N.; Kimura, H.; Honda, R.

    2012-12-01

    The Japanese government has estimated the probability of earthquake occurrence with magnitude 7-class during the next 30 years as 70 %. This estimation is based on five earthquakes that occurred in this area in the late 120 years. However, it has been revealed that this region is lying on more complicated tectonic condition due to the two subducted plates and the various types of earthquakes which have been caused by. Therefore, it is necessary to classify these earthquakes into inter-plate earthquakes and intra-plate ones. Then, we have been constructing a seismic observation network since 5 years ago. Tokyo Metropolitan area is a densely populated region of about 40 million people. It is the center of Japan both in politics and in economy. So that human activities have been conducting quite busily, this region is unsuitable for seismic observation. Then, we have decided to make an ultra high dense seismic observation network. We named it the Metropolitan Seismometer Observation Network; MeSO-net. MeSO-net consists of 296 seismic stations. Minimum interval is about 2km and average interval is about 5km.We picked the P- and S-wave arrival times manually. We applied double-difference tomography method to the dataset and estimated the velocity structure. We depicted the plate boundaries from the newly developed velocity model. And, we referred to the locations of the repeating earthquakes, the distributions of normal hypocenters and the focal mechanisms. Our plate model became relatively flat and a little shallower than previous one.Seismicity of Metropolitan area after the M9 event was compared to the one before M9 event. The seismic activity is about 4 times as high as before the M9 event occurred. We examined spatial distribution of the activated seismicity with respect to the newly developed plate configuration. The activated events are located on upper boundaries and they have almost thrust type mechanisms. Recently, a slow slip event has occurred on October in

  6. Malformaciones congénitas en hijos de madres epilépticas con y sin tratamiento con anticonvulsivantes Congenital malformations in the offspring of epileptic mothers with and without anticonvulsant treatment

    Directory of Open Access Journals (Sweden)

    Jazmín Arteaga-Vázquez

    2012-12-01

    Full Text Available OBJETIVO: Determinar la frecuencia y tipo de malformaciones congénitas (MC en hijos de madres epilépticas (HME tratadas y no tratadas con anticonvulsivantes, la posible correlación anticonvulsivante/MC y la asociación con otras alteraciones del desarrollo. MATERIAL Y MÉTODOS: Estudio multicéntrico de casos y controles en 166 recién nacidos vivos HME identificados en 21 501 recién nacidos con MC y respectivos controles del Registro y Vigilancia Epidemiológica de Malformaciones Congénitas (RYVEMCE. RESULTADOS: La frecuencia de MC en HME tratadas fue mayor, (48.3% que en HME no tratadas (28.3%; (RM= 2.37 IC95% 1.08-5.40, p=0.03. Las MC más frecuentes fueron espina bífida, anomalías en reducción de miembros, labio/paladar hendido, microcefalia, anotia/microtia, hipospadias, paladar hendido, polidactilia, anoftalmia/microftalmia y onfalocele. No hubo diferencias entre uso de mono o politerapia. La difenilhidantoína, carbamazepina y ácido valproico fueron los anticonvulsivantes más utilizados. CONCLUSIONES: Los resultados confirman la teratogenicidad propia de la epilepsia y el efecto sinérgico de ciertos anticonvulsivantes, lo que evidencia la necesidad de un apropiado control periconcepcional de esta enfermedad y su tratamiento.OBJECTIVE: To determine the prevalence at birth and type of congenital malformations (CM in newborns of epileptic mothers (NEM treated and not treated with anticonvulsants, the correlation anticonvulsant/CM and other developmental disorders. MATERIALS AND METHODS: Multicenter case-control study, in 166 live births NEM diagnosed in 21 501 newborns with CM and respective controls from the Registro y Vigilancia Epidemiológica de Malformaciones Congénitas (RYVEMCE. RESULTS: The frequency of CM in NEM treated with anticonvulsants was higher (48.3% than in NEM of untreated mothers (28.3%, (OR= 2.37 IC95% 1.08-5.40, p=0.03. CMs most frequently found were: spina bifida, limb reduction defects, cleft lip palate

  7. Detección de Treponema pallidum subespecie pallidum para el diagnóstico de sífilis congénita mediante reacción en cadena de la polimerasa anidada.

    Science.gov (United States)

    Pinilla, Gladys; Campos, Lesly; Durán, Andrea; Navarrete, Jeannette; Muñoz, Liliana

    2018-03-15

    Introducción. La sífilis es una enfermedad producida por Treponema pallidum subespecie pallidum cuya incidencia mundial es de 12 millones de casos por año, aproximadamente; de estos, más de dos millones se presentan en mujeres gestantes, siendo la sífilis congénita la complicación más grave de esta infección en el embarazo.Objetivo. Detectar la presencia de T. pallidum subespecie pallidum en muestras clínicas para el diagnóstico de sífilis congénita mediante reacción en cadena de la polimerasa (PCR) anidada y determinar su concordancia con las pruebas serológicas.Materiales y métodos. Mediante PCR convencional y anidada, se amplificaron tres genes diana (polA, 16S ADNr y TpN47) y se confirmaron los productos de amplificación de los genes TpN47 y polA por secuenciación. Las pruebas serológicas empleadas fueron la VDRL (Venereal Disease Research Laboratory), la de reagina plasmática rápida (Rapid Plasma Reagin, RPR) y la de aglutinación de partículas para Treponema pallidum (Treponema pallidum Particle Agglutination Assay, TPPA).Resultados. La sensibilidad para la PCR convencional fue de 52 pg y, para la PCR anidada, de 0,52 pg. La especificidad con los iniciadores TpN47 y polA fue de 100 %; los resultados de la secuenciación mostraron una identidad de 97 % con T. pallidum. En 70 % de las muestras, los resultados de las pruebas serológicas y la PCR anidada concordaron.Conclusión. El gen TpN47 resultó ser el mejor blanco molecular para la identificación de T. pallidum. La PCR anidada se presenta como una alternativa de diagnóstico molecular promisoria para el diagnóstico de sífilis congénita.

  8. Reconstrucción genital integral en la Hiperplasia Suprarrenal Congénita: sensibilidad, estética y función (embarazo Integral genital reconstruction: sensitivity, aesthetic and function (pregnancy, in the Congenital Adrenal Hyperplasia

    Directory of Open Access Journals (Sweden)

    A.A. Núñez Serrano

    2010-03-01

    Full Text Available La Hiperplasia Suprarrenal Congénita o Síndrome Adrenogenital es un cuadro clínico poco frecuente. Las anomalías que presenta van asociadas a síndromes que a veces son muy complejos, destacando, entre otros, el seudohermafroditismo femenino y el hermafroditismo verdadero. Las mujeres que la padecen presentan como alteración más evidente un clítoris aumentado de tamaño (megaloclítoris y otras alteraciones en los genitales externos. Ante estas pacientes es necesario realizar un diagnostico correcto mediante exploración física y otras pruebas complementarias: estudios genéticos, analíticos, hematológicos y urinarios. La corrección quirúrgica del megaloclítoris es necesaria no sólo para mejorar el aspecto de los genitales externos, sino también para que tanto la paciente como su familia se encuentren menos afectados psicológicamente. Existen varias técnicas quirúrgicas que intentan corregir esta malformación, como la amputación o clitorectomía total, la retroposición o enterramiento y la clitorectomía parcial selectiva. Todas ellas, junto con otras correcciones de los genitales externos afectados, han sido utilizadas hasta el día de hoy. Presentamos el caso de una paciente con Hiperplasia Suprarrenal Congénita por déficit del enzima 21-hidroxilasa. Describimos su clínica, la técnica quirúrgica aplicada en su caso y, sobre todo, dado la rareza de esta patología, comunicamos que, tras dos embarazos, los dos hijos nacidos, no presentaron la alteración congénita materna.Congenital Adrenal Hyperplasia is a rare patology, whith clinical expressions like female pseudohermaphroditism or true hermaphroditism. Females affected mainly suffer clitoral hypertrophy and external genitalia abnormalityes. The complete diagnosis includes: careful examination of the genitals, complementary imaging proofs, hormonal and genetic testing. The surgical correction of the external genitals and megaloclitoris improves the physical and

  9. Book of presentations. Tokyo Tech COE-INES. Indonesia international symposium 2005. 'Prospect of nuclear energy in Indonesia'

    International Nuclear Information System (INIS)

    2005-03-01

    The symposium of the title was organized by the 21st Century COE Program, Innovative Nuclear Energy Systems for Sustainable Development of the World, the Tokyo Institute of Technology (Tokyo Tech COE-INES), the Bandung Institute of Technology (ITB), and the National Nuclear Energy Agency of Indonesia (BATAN). The symposium included presentations of 21 from Japan 24 from Indonesia and discussions on innovative nuclear energy systems and on a number of topics related to nuclear energy, including long-term policies and regulation for its development. Students from Japan and Indonesia played an important role in the symposium, presenting excellent work and discussion on their research topics as well as participating in very fruitful panel discussions on 'Education in Nuclear Field' and 'Attractiveness of Jobs in the Nuclear Field'. (J.P.N.)

  10. Bacteriological and Epidemiological Characteristics of Enterotoxigenic Escherichia coli Isolated in Tokyo, Japan, between 1966 and 2009 ▿

    Science.gov (United States)

    Konishi, Noriko; Obata, Hiromi; Monma, Chie; Nakama, Akiko; Kai, Akemi; Tsuji, Takao

    2011-01-01

    Enterotoxigenic Escherichia coli (ETEC) caused 131 outbreaks in Tokyo, Japan, between 1966 and 2009. The major serogroups were O6, O27, O148, and O159. The incidence of serogroups O25 and O169 recently increased. Heat-stable enterotoxin (ST) subtyping revealed that E. coli of serogroups O6, O15, O25, and O159 possessed the STh gene, whereas those serotyped as O27 and O169 possessed the STp gene. PMID:21752981

  11. Could the Tokyo guidelines on the management of acute cholecystitis be adopted in developing countries? Experience of one center.

    Science.gov (United States)

    Bouassida, Mahdi; Charrada, Hédi; Feidi, Bilel; Chtourou, Mohamed Fadhel; Sassi, Sélim; Mighri, Mohamed Mongi; Chebbi, Fethi; Touinsi, Hassen

    2016-05-01

    The Tokyo guidelines for diagnostic criteria and severity assessment of acute cholecystitis (AC), published in 2007, recommend early laparoscopic cholecystectomy (ELC) be done as soon as possible after the onset of symptoms. We conducted this study to analyze the changes in the therapeutic strategy for AC in a surgical center in Tunisia after the Tokyo guidelines were published. Between January, 2005 and January, 2013, 649 patients underwent cholecystectomy for AC at the Department of Surgery, Mohamed Tahar Maamouri Hospital in Nabeul, Tunisia. The study period was subdivided into before (n = 192) and after (n = 457) the publication of the Tokyo guidelines, that is, prior to and including 2007, and from 2008 onward, respectively. We reviewed patient records retrospectively to collect demographic data, biochemical data, radiological findings, and postoperative outcomes. All these factors were compared between the groups. The duration of symptoms before surgery was significantly longer before 2008 (p = 0.018). ELC was significantly more frequent after 2008 (p = 0.001). Laparoscopic surgery was converted to open surgery in 16.1 % of patients before 2008 vs. 7.8 % of patients after 2008 (p = 0.02). There were no significant differences in bile duct injury or postoperative complications between the groups. The length of preoperative, postoperative, and total hospital stay was longer before 2008. ELC is a safe and effective therapeutic strategy for AC. The Tokyo guidelines resulted in a significant increase in the number of ELCs being performed and significantly reduced preoperative and total hospital stay without increasing intra- and postoperative complications. Importantly, ELC reduced medical costs, which is crucial for a country with limited resources, such as Tunisia.

  12. A Japanese-American Sam Spade: The Metaphysical Detective in Death in Little Tokyo, by Dale Furutani

    OpenAIRE

    Portilho Carla

    2017-01-01

    The aim of this essay is to discuss the legacy of the roman noir in contemporary detective fiction produced outside the hegemonic center of power, here represented by the novel Death in Little Tokyo (1996), written by Japanese-American author Dale Furutani. Starting from the concept of the metaphysical detective (Haycraft 76; Holquist 153-156), characterized by deep questioning about narrative, interpretation, subjectivity, the nature of reality and the limits of knowledge, this article propo...

  13. Recreating of rurality around the totoro forest in the outer fringe of tokyo metropolitan area : the spirituality of rurality

    OpenAIRE

    Kikuchi, Toshio; Obara, Norihiro

    2005-01-01

    In this paper we made a point of rural land use and its conservation as the reflection of rurality in outer fringes, and discussed about recreating of rurality with utilising its conservation activities and the spirituality. In Sayama hill region of Tokyo metropolitan area, restructuring of rural land use and recreating rurality have been practised with conservation and maintenance activities in the Totoro forest. Although rural and urban residents think about those activities and their parti...

  14. Teaching of severe accident of Fukushima Daiichi Nuclear Power Plants of Tokyo Electric Power

    International Nuclear Information System (INIS)

    Saito, Shinzo

    2011-01-01

    The Great East Japan Earthquake and accompanied tsunami brought about the severe accident at Fukushima Daiichi Nuclear Power Plants of Tokyo Electric Power Co., Inc. For 'No more Fukushima', twelve teaching of the accident was pointed out as follows: 1) natural disasters and external events shall be taken into consideration, 2) severe accident shall be included into safety regulation, 3) all possibility of hydrogen explosion shall be excluded, 4) diversity of safety important component and equipment shall be added with sufficient period of outage, 5) siting of multiple units at the same site shall be avoided at quake-prone country like Japan, 6) accident response environment for operators shall be improved, 7) accident convergence termination system shall be established so as to concentrate technical experience and knowledge, 8) off-site center shall be improved, 9) resident evacuation, consumption limit of food, radiation exposure and soil contamination limit shall be decided openly, 10) nuclear regulation and prevention of disaster shall be conducted by unitary organization to gain public trust, 11) fostering of safety culture among relevant enterprises shall be more encouraged and 12) nuclear industry shall develop reactor such as with no core meltdown or no evacuation and environmental contamination even if reactor core would be meltdown. (T. Tanaka)

  15. Reversed field pinch device of University of Tokyo, REPUTE-I

    International Nuclear Information System (INIS)

    Inoue, Nobuyuki

    1985-01-01

    In the University of Tokyo, the research project on a reversed field pinch device started in fiscal year 1983, and the experimental facility REPUTE-1 was constructed. This project is the common project of Science and Engineering Departments, and the facility is used for the research on the plasma in a nuclear fusion reactor core and the education of students. The point that the REPUTE-1 is different from other reversed field pinch devices is that its shell is resistive. It was confirmed by the initial experiment that even though the shell was not electroconductive, a reversed field configuration was formed. The subject for the future is to maintain the equilibrium of plasma by outside normal magnetic fields instead of depending on the shell. The reason why a reversed field pinch device was selected is explained. In fiscal year 1984, the preparation of various instruments for plasma measurement was carried out. The reversed field pinch devices are superior to tokamaks in the principle of plasma containment and the reactor engineering potential. The outline of reversed field pinch devices and the REPUTE-1, and the results of initial experiment are reported. (Kako, I.)

  16. Toxic evaluations of sediments in Tokyo Bay, Japan, using Japanese medaka embryos.

    Science.gov (United States)

    Uno, Seiichi; Kokushi, Emiko; Kawano, Machi; McElroy, Anne E; Koyama, Jiro

    2017-12-01

    Toxic risks of sediments collected from seven sites in Tokyo Bay were evaluated using Japanese medaka embryos. Those sediments with slight pore water were placed in grass petri dishes without overlying water. The most remarkable effect in the field sediment was to cause hatching delay in embryos, and the longest time until hatching took was 12.5 ± 1.6 days post-fertilization (dpf), although that in control group was 10.1 ± 0.7 dpf. A significant delay in hatching was observed at four sites. Because total carbon concentrations were relatively high in sediments at three of these four sites, several chemicals were expected to be residues in these sites and could cause their delay. Although extreme mortality was not observed at all sites, sediments collected from the site close to Kawasaki city induced 10 % mortality. Polycyclic aromatic hydrocarbon (PAH) concentrations were remarkably high at this site compared with other sites, and thus PAH toxicities could be causing the mortality. Concentration of heavy metals such as cadmium, copper, lead, and zinc in sediments were also determined, but no clear relationship was found between toxicities to embryos and the distribution of their concentrations.

  17. Statistical distribution of building lot frontage: application for Tokyo downtown districts

    Science.gov (United States)

    Usui, Hiroyuki

    2018-03-01

    The frontage of a building lot is the determinant factor of the residential environment. The statistical distribution of building lot frontages shows how the perimeters of urban blocks are shared by building lots for a given density of buildings and roads. For practitioners in urban planning, this is indispensable to identify potential districts which comprise a high percentage of building lots with narrow frontage after subdivision and to reconsider the appropriate criteria for the density of buildings and roads as residential environment indices. In the literature, however, the statistical distribution of building lot frontages and the density of buildings and roads has not been fully researched. In this paper, based on the empirical study in the downtown districts of Tokyo, it is found that (1) a log-normal distribution fits the observed distribution of building lot frontages better than a gamma distribution, which is the model of the size distribution of Poisson Voronoi cells on closed curves; (2) the statistical distribution of building lot frontages statistically follows a log-normal distribution, whose parameters are the gross building density, road density, average road width, the coefficient of variation of building lot frontage, and the ratio of the number of building lot frontages to the number of buildings; and (3) the values of the coefficient of variation of building lot frontages, and that of the ratio of the number of building lot frontages to that of buildings are approximately equal to 0.60 and 1.19, respectively.

  18. Systematic Education of Self-Medication at Tokyo University of Pharmacy and Life Sciences.

    Science.gov (United States)

    Narui, Koji; Samizo, Kazuo; Inoue, Michiko; Watanabe, Kinzo

    2016-01-01

    The promotion of self-medication by pharmacies, with the aim of encouraging a patient's self-selection of proper OTC drug, is written about in the national action plan "Japan is Back". The subject of self-medication has been improved in the 2013 revised edition of "Model Core Curriculum for Pharmaceutical Education". At Tokyo University of Pharmacy and Life Sciences, the systematic education of self-medication was started from the onset of the six-year course in the third, fourth and fifth grade. We introduce here a new approach in our systematic education of self-medication. In the practice of the fourth grade, groups of around 5-6 students are formed. The pharmacy students assume various roles-of pharmacist, rater, observer, and chairman-and perform role-playing. We prepared a standardized patient (SP) showing various symptoms. The student of the role of pharmacist asks about the SP's symptoms, chooses an OTC drug suitable for the SP, and explains the OTC drug to the SP. After the role-playing, those in the roles of rater, observer, SP, and faculty give feedback to the student who played the role of pharmacist. Because we conduct this role-playing using SPs with a variety of symptoms, we can create a situation similar to a real drugstore.

  19. Condensate demineralizer system for Fukushima Daiichi Nuclear Power Station, the Tokyo Electric Power Co., Inc

    International Nuclear Information System (INIS)

    Ariyoshi, Shigeki; Ikeda, Yukio; Kuramoto, Kenji; Omori, Yoshi; Yamamoto, Hiroyoshi

    1975-01-01

    This paper describes the condensate demineralizing equipment recently supplied to the second, third, and fifth power units of the Fukushima Daiichi Nuclear Power Station of the Tokyo Electric Power Company, Inc. The output of this equipment is rated as 4,900 m 3 /h each, which is currently the largest capacity for this type of equipment in Japan. The purpose of this equipment is to remove any ion components and suspended solids contained in condensate to improve its water purity. By doing so, decreasing the corrosion rate of materials used in the plant and, at the same time, decreasing the radioactivity of the condensate, thus easing the whole plant operation can be achieved. The same kind of equipment is also employed at the conventional thermal power stations, but the required functioning and operating mode are quite different. In the case of the nuclear power plant, extremely severe requirements specific with nuclear technology must be met which arise solely from dealing with radioactive substances. Not only the water treatment method, but also layout and arrangement, operation and liquid waste processing methods differ from those for the conventional power plants. The equipment for the sixth unit at Fukushima is now under designing and that for the Tokai No.2 unit of the Japan Atomic Power Company is already under shop fabrication. Both have the rated capacity of 7,300 m 3 /h each, which exceeds far up the capacity of the previously mentioned equipment. (auth.)

  20. Investigation of radon and thoron concentrations in a landmark skyscraper in Tokyo

    International Nuclear Information System (INIS)

    Kazumasa Inoue; Masahiro Fukushi

    2013-01-01

    The temporal variation of the radon concentration, and the radon and thoron concentrations every 3 months for a year were measured using two types of devices in a landmark skyscraper, the Tokyo Metropolitan Government Daiichi Building. In the measurement of temporal variation of the radon concentration using a pulse type ionization chamber, the average radon concentration was 21 ± 13 Bq m -3 (2-68 Bq m -3 ). The measured indoor radon concentration had a strong relationship with the operation of the mechanical ventilation system and the activities of the office workers. The radon concentration also increased together with temperature. Other environmental parameters, such as air pressure and relative humidity, were not related to the radon concentration. In the long-term measurements using a passive radon and thoron discriminative monitor, no seasonal variation was observed. The annual average concentrations of radon and thoron were 16 ± 8 and 16 ± 7 Bq m -3 , respectively. There was also no relationship between the two concentrations. The annual average effective dose for office workers in this skyscraper was estimated to be 0.08 mSv y -1 for 2000 working hours per year. When considering the indoor radon exposure received from their residential dwellings using the annual mean radon concentration indoors in Japan (15.5 Bq m -3 ), the annual average effective dose was estimated to be 0.37 mSv y -1 . This value was 31 % of the worldwide average annual effective dose. (author)

  1. Clinical evaluation of the Tokyo Guidelines 2013 for severity assessment of acute cholangitis.

    Science.gov (United States)

    Nishino, Takayoshi; Hamano, Tetsuya; Mitsunaga, Yutaka; Shirato, Izumi; Shirato, Miho; Tagata, Tomoko; Shimada, Masahiko; Yoshida, Shuhei; Mitsunaga, Atsushi

    2014-12-01

    We evaluated the severity assessment criteria for acute cholangitis (AC) of the Tokyo Guidelines 2013 (TG13) and developed a scoring system for predicting the need for urgent/early biliary drainage. We retrospectively reviewed 66 AC cases prospectively managed based on the TG07 and divided into an urgent/early biliary drainage group (n = 30) and elective biliary drainage group (n = 36). There were 26 mild, 27 moderate, and 13 severe cases based on the TG13. The TG13 assessment in 12 of the 17 cases requiring early biliary drainage based on the TG07 was moderate, but underestimated the other five cases as mild AC. When five predictors (blood urea nitrogen >20 mg/dL, SIRS presence, platelet count <120 000/μL, serum albumin level <3.0 g/dL, age ≥75 years old) were used to devise a scoring system, the receiver-operator characteristic curve of the scores showed good test performance for predicting the need for urgent/early biliary drainage. The area under the curve (AUC) was 0.95 and higher than the TG13 AUC (0.80). The TG13 is practical, but some AC cases requiring urgent/early biliary drainage were underestimated as mild AC. The scoring system allows identification of high-risk AC patients and will improve the TG13. © 2014 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

  2. Assessing the Allocation of Special Elderly Nursing Homes in Tokyo, Japan.

    Science.gov (United States)

    You, Ninglong; Shen, Zhenjiang; Nishino, Tatsuya

    2017-09-22

    Social welfare and public health departments require reliable assessments to enhance the rationality of phased construction of special elderly nursing homes (SENHs). This paper aims to assess the allocation of SENHs based on a beds-needed index for SENHs (BNIS). This may help departments determine the priority for approving locations of SENHs more accurately with a limited budget. Traditional assessments in Tokyo use the sphere of welfare, ward, and sphere of daily life as spatial units for estimating beds-to-elderly population ratios. We calculate the BNIS by introducing a parameter-improved floating catchment area method (PI-FCA) at a smaller spatial unit, the Chome. In the PI-FCA, the catchment area is generated according to the standard of average population served by SENHs and capacity, the population demand is the population of the elderly requiring care levels 3-5 and is further modified by a coefficient of potential demand via building a multivariate linear model. Improved results were obtained using the PI-FCA. Finally, this study maps the distribution of the degree of BNIS, to provide a basis for the allocation assessment of SENHs. This caters to the needs of departments and is easily applicable in other public healthcare facilities.

  3. Characteristics of cancer patients who died by suicide in the Tokyo metropolitan area.

    Science.gov (United States)

    Fujimori, Maiko; Hikiji, Wakako; Tanifuji, Takanobu; Suzuki, Hideto; Takeshima, Tadashi; Matsumoto, Toshihiko; Yamauchi, Takashi; Kawano, Kenji; Fukunaga, Tatsushige

    2017-05-01

    The purpose of this study was to investigate the sociodemographic characteristics of cancer patients who died by suicide in comparison with cancer-free cases. Suicide data from the Tokyo Medical Examiner's Office from 2009 to 2013 were extracted retrospectively. A total of 503 (5.1%) out of 9841 people who committed suicide had cancer; age ranged from 26 to 97 years. The cancer patients were significantly older than the cancer-free cases. There were significantly more cancer patients with cohabiters than cancer-free cases with cohabiters. Only half of young to middle-aged subjects had a job in both groups. There were significantly more cancer patients who lived on pensions and welfare assistance, and less cancer patients who drink or smoke than those without cancer. Given the high incidence of suicide in elderly cancer patients, healthcare professionals should pay attention for risk even in cancer patients who have cohabiters, benefit from a pension, and do not drink or smoke. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Spatiotemporal dynamics of urban green spaces and human–wildlife conflicts in Tokyo

    Science.gov (United States)

    Hosaka, Tetsuro; Numata, Shinya

    2016-01-01

    Although urban green spaces are increasingly important both for humans and wildlife, an increase in urban green spaces may also increase human–wildlife conflicts in urban areas. However, few studies have examined the relationship between the size of green spaces and the level of conflicts with wildlife in multiple taxa, including invertebrates and vertebrates. To better understand current pest statistics and predict changes that will occur as the area of green spaces increases, we analysed a dataset compiling the number of pest consultations in 53 metropolitan districts in Tokyo over a 20-year period and its relationships with the area of green space. Stinging insects (e.g., wasps) made up over 50% of pest consultations, followed (in order) by rats and other nuisance animals (e.g., snakes). The number of consultations per unit population did not correlate, or was even negatively correlated, with the proportions of green spaces (mainly forest) for many indoor pests, but did positively correlate for some outdoor pests, such as wasps and snakes. Therefore, wasps and snakes can increase when urban green spaces increase. Because even minor nuisances are relevant for urban lifestyles, considerations of ways to minimise conflicts with wildlife are critical for urban green space management. PMID:27481578

  5. Patients' perceptions of vocal problems: results from a survey in the Tokyo area.

    Science.gov (United States)

    Tsunoda, Koichi; Fujimaki, Yoko; Nito, Takaharu; Yamasoba, Tatsuya; Tayama, Niro; Makiyama, Kiyoshi; Murofushi, Toshihisa; Tsunoda, Atsunobu; Ohshima, Kiyoshi; Nishiyama, Kohichiro; Kano, Shigeru; Niimi, Seiji

    2015-06-01

    Laryngoscopy in cases of sulcus vocalis reveals bowed vocal folds, resulting in a spindle-shaped chink with glottal incompetence. The anatomic and functional problems and resulting incomplete glottal closure during phonation lead to the presenting symptoms of breathy hoarseness, decrease in maximum phonation time (MPT), and vocal fatigue. These symptoms, however, have been reported from the physician's viewpoint, not the patient's. Furthermore, no standardized guidelines for the treatment of sulcus vocalis have been established. Because the general attitude toward sulcus vocalis appears to have become 'It is only a vocal problem and does not significantly affect the patient's well-being,' knowledge of sulcus vocalis has decreased and knowledge about choices of therapy remain limited. We therefore conducted an epidemiological questionnaire survey on this pathological condition in voice clinics in seven hospitals in the Tokyo area to establish preliminary guidelines for the management of sulcus vocalis, in reference to the opinion of the patients. Here we report the summary of our preliminary study 'a survey for sulcus vocalis' and suggest guidelines for the management of such pathological conditions. Although these management guidelines may result in improvement in the symptoms of sulcus vocalis, patients and physicians should be aware that treatment of this condition is difficult and improvement is not guaranteed.

  6. Seismic Wavefield Imaging of Long-Period Ground Motion in the Tokyo Metropolitan Area, Japan

    Science.gov (United States)

    Nagao, H.; Kano, M.; Nagata, K.; Ito, S. I.; Sakai, S.; Nakagawa, S.; Hori, M.; Hirata, N.

    2017-12-01

    Long-period ground motions due to large earthquakes can cause devastating disasters, especially in urbanized areas located on sedimentary basins. To assess and mitigate such damage, it is essential to rapidly evaluate seismic hazards for infrastructures, which can be simulated by seismic response analyses that use waveforms at the base of each infrastructure as an input ground motion. The present study reconstructs the seismic wavefield in the Tokyo metropolitan area located on the Kanto sedimentary basin, Japan, from seismograms of the Metropolitan Seismic Observation network (MeSO-net). The obtained wavefield fully explains the observed waveforms in the frequency band of 0.10-0.20 Hz. This is attributed to the seismic wavefield imaging technique proposed by Kano et al. (2017), which implements the replica exchange Monte Carlo method to simultaneously estimate model parameters related to the subsurface structure and source information. Further investigation shows that the reconstructed seismic wavefield lower than 0.30 Hz is of high quality in terms of variance reduction (VR), which quantifies a misfit in waveforms but that the VR rapidly worsens in higher frequencies. Meanwhile, the velocity response spectra show good agreement with observations up to 0.90 Hz in terms of the combined goodness of fit (CGOF), which is a measure of misfit in the velocity response spectra. Inputting the reconstructed wavefield into seismic response analyses, we can rapidly assess the overall damage to infrastructures immediately after a large earthquake.

  7. Urinary inorganic arsenic concentrations and semen quality of male partners of subfertile couples in Tokyo.

    Science.gov (United States)

    Oguri, Tomoko; Yoshinaga, Jun; Toshima, Hiroki; Mizumoto, Yoshifumi; Hatakeyama, Shota; Tokuoka, Susumu

    2016-01-01

    Inorganic arsenic (iAs) has been known as a testicular toxicant in experimental rodents. Possible association between iAs exposure and semen quality (semen volume, sperm concentration, and sperm motility) was explored in male partners of couples (n = 42) who visited a gynecology clinic in Tokyo for infertility consultation. Semen parameters were measured according to WHO guideline at the clinic, and urinary iAs and methylarsonic acid (MMA), and dimethylarsinic acid concentrations were determined by liquid chromatography-hydride generation-ICP mass spectrometry. Biological attributes, dietary habits, and exposure levels to other chemicals with known effects on semen parameters were taken into consideration as covariates. Multiple regression analyses and logistic regression analyses did not find iAs exposure as significant contributor to semen parameters. Lower exposure level of subjects (estimated to be 0.5 μg kg(-1) day(-1)) was considered a reason of the absence of adverse effects on semen parameters, which were seen in rodents dosed with 4-7.5 mg kg(-1).

  8. Ambulance Transport of the Oldest Old in Tokyo: A Population-Based Study

    Science.gov (United States)

    Tokuda, Yasuharu; Abe, Toshikazu; Ishimatsu, Shinichi; Hinohara, Shigeaki

    2010-01-01

    Background Few studies have investigated ambulance utilization in people aged 85 years or older, ie, the oldest old. Methods We conducted a 1-year population-based observational study of patients transported by ambulance to emergency departments in Tokyo, Japan, which has a population of about 12 million. Demographic data, symptoms/events associated with ambulance transport, and the proportion of hospital admissions were recorded. Transport rates by age and sex were calculated using data for the background population and ambulance transports, and the 10 most frequent symptoms/events requiring transport were compared between the oldest old and those aged 65 to 84 years. Results Of the 642 764 patients who were transported to hospitals by ambulances, 59 570 (9%) were aged ≥85 years; 64% were women. The annual ambulance transport rate for this population was 250 per 1000/year and was significantly greater than the rate (90 per 1000/year) for those aged 65 to 84 years. The highest rate was for men aged 85 to 99 years (292 per 1000/year). Among the oldest old, the most frequent reason for ambulance transport was fall (38.5 per 1000/year), and the symptom most likely to result in hospital admission was dyspnea. Conclusions The ambulance transport rate for the oldest old was high, particularly among men aged ≥95 years. To reduce the need for ambulance transport among the oldest old, preventive care is needed to reduce falls and acute exacerbations of cardiac and respiratory disorders. PMID:20814165

  9. Geochemical and stable isotope characteristics of urban heavy rain in the downtown of Tokyo, Japan

    Science.gov (United States)

    Uchiyama, Ryunosuke; Okochi, Hiroshi; Ogata, Hiroko; Katsumi, Naoya; Asai, Daisuke; Nakano, Takanori

    2017-09-01

    In order to make clear the impact of air pollution on the formation of sudden and locally-distributed heavy rain in urban area (hereafter Urban Heavy Rain: UHR), we analyzed inorganic ion concentration and stable isotope ratio of water (δD and δ18O) in rainwater. Rainwater samples were collected in Shinjuku, which is a representative downtown of Tokyo, Japan, during four years from October 2012 to December 2015. The concentration and wet deposition fluxes of acidic components (H+, NH4+, NO3-, and nss-SO42 -) in UHR were especially higher than those in other types of rain events, i.e. normal rain, typhoon heavy rain, and frontal heavy rain. UHR had distinctly lower stable isotope ratios than those in other urban rains with same rainfall amount and summer precipitation systems. There was a high negative correlation between δ18O and the distances from the sampling point to the formation area of UHR within 10 km, while there were high positive correlations between δ18O and the concentration of acidic components in UHR. These findings indicate that UHR could effectively scavenge acidic substances within cloud and suggest the use of stable isotope ratios as tracers of an urban heavy rain's water and in-cloud scavenging process.

  10. Perkembangan Perumahan Publik di Negeri Sakura: Studi Kasus pada Perumahan di Tokyo dan Sekitarnya

    Directory of Open Access Journals (Sweden)

    Nina Nurdiani

    2011-12-01

    Full Text Available Japan currently has been successful to provide housing for low to high-income people in urban areas. Almost everyone in Japan can access their homes, either public housing or private one, depending on the level of their welfare status. The study discusses about development of public housing in Japan and why the Japanese people can accept the design of the vertical housing built by their government. The study is conducted with descriptive approach through literature study and field observations in the city of Tokyo and its surrounding areas to provide knowledge about the development of public housing in Japan started from traditional residential and then developed into a modern residential horizontally and vertically according to the needs of his hometown community. Despite of the development from time to time, the design of residence still considers the local culture of Japan. So the Japanese people can receive residential design, although it is developed into vertical housing. This study is expected to give inputs for the Indonesian government as an effort to achieve the successful provision of public housing in Indonesia. 

  11. Contamination, distribution and pathogenicity of Toxocara canis and T. cati eggs from sandpits in Tokyo, Japan.

    Science.gov (United States)

    Macuhova, K; Akao, N; Fujinami, Y; Kumagai, T; Ohta, N

    2013-09-01

    The contamination, distribution and pathogenicity of Toxocara canis and T. cati eggs in sandpits in the Tokyo metropolitan area, Japan, are described. A total of 34 sandpits were examined, 14 of which were contaminated with T. cati eggs, as assessed by the floatation method and polymerase chain reaction (PCR) analysis. Two naturally contaminated sandpits were investigated to determine the vertical and horizontal distribution of eggs, and an inverse relationship between the sand depth and number of eggs was observed. To examine the pathogenicity of the eggs, three ICR mice were inoculated with 300 eggs, which were recovered from sandpits. The mice exhibited eosinophilia in the peripheral blood and IgG antibody production in the sera after 3 weeks of infection. Most migrating larvae were recovered from carcasses, although three were found in the brains of two infected mice. These three larvae were determined to be T. canis by PCR, revealing that not only T. cati, but also T. canis eggs could be found in sandpits and, further, that eggs recovered from sandpits have the ability to invade a paratenic host.

  12. Periodical public opinion survey on nuclear energy. Inhabitants living in the Tokyo metropolitan area

    International Nuclear Information System (INIS)

    Shinoda, Yoshihiko; Tsutida, Shouji; Kimura, Hiroshi

    2014-01-01

    Fukushima Daiichi nuclear power plant accident (Fukushima accident) has brought about a great change in many people's perceptions about nuclear power plant safety. When discussing future energy options for Japan, it is important to have a full grasp of the attitude of a large number of people towards nuclear energy. The Atomic Energy Society of Japan has conducted annual questionnaire survey of 500 adults who live within 30 kilometers of Tokyo Station. The aim of this survey is to assess trends in public attitude towards nuclear energy. The authors that designed the questionnaire entries of this survey have been managing questionnaire data as members of the Data Management Working Group under the Social and Environmental Division of the Atomic Energy Society of Japan. We confirmed the change in public attitude towards nuclear energy through this periodical survey after the Fukushima accident. In particular, public concerns about the use of nuclear energy increased after the Fukushima accident, and many people have raised doubts over the use of nuclear energy in the future. (author)

  13. Radiation therapy for Kaposi's sarcoma associated with acquired immunodeficiency syndrome. Tokyo Metropolitan Komagome Hospital experience

    International Nuclear Information System (INIS)

    Ebara, Takeshi; Karasawa, Katsuyuki; Maebayashi, Katsuya; Kurosaki, Hiromasa; Ishikawa, Hitoshi; Kaizu, Toshihide; Tanaka, Yoshiaki; Akagi, Kumiko; Masuda, Gota

    2000-01-01

    Kaposi's sarcoma is frequently found in association with acquired immunodeficiency syndrome (AIDS). We report on radiotherapy for patients with AIDS-related Kaposi's sarcoma at Tokyo Metropolitan Komagome Hospital. Between April 1991 and May 1997, radiotherapy was given to 11 lesions in eight men with AIDS-related Kaposi's sarcoma to relieve their symptoms. The lesions involved the head and neck region, the legs, and the gastrointestinal tract. Radiotherapy was carried out with 4-MV photon through parallel opposed field or high energy electrons. Total doses ranged from 20 to 38 Gy, with a median of 30 Gy, delivered in 2- to 3-Gy fractions. Four patients were given other treatments prior to the radiotherapy. Acute reaction was evaluated according to the modified acute radiation morbidity scoring criteria of the Radiation Therapy Oncology Group (RTOG). Radiotherapy had relieved the symptoms in all patients at completion of this therapy. Lesions that involved the hard palate and vocal cords had completely disappeared. The lesions that received radiotherapy were controlled without symptoms until the patients died. Patients who had the head and neck region treated exhibited severe acute mucosal reaction (at a dose of 30 Gy, there was grade 2 morbidity by modified RTOG criteria, in two patients, and grade 3 in three patients) although the radiation therapy was completed for these patients. Radiotherapy promises a favorable outcome for symptom relief in AIDS-related Kaposi's sarcoma. (author)

  14. Comparison of two editions of Tokyo guidelines for the management of acute cholangitis.

    Science.gov (United States)

    Sun, Gang; Han, Lu; Yang, Yunsheng; Linghu, Enqiang; Li, Wen; Cai, Fengchun; Kong, Jinyan; Wang, Xiangdong; Meng, Jiangyun; Du, Hong; Wang, Hongbin; Huang, Qiyang; Hyder, Quratulain; Zhang, Xiuli

    2014-02-01

    The Tokyo guidelines from 2007 (TG07) and 2013 (TG13) were compared for the management of acute cholangitis (AC). We reviewed patients with clinically-proven AC by detecting purulent biles during biliary drainage. TG07 and TG13 were compared regarding diagnosis, severity grading and prognostic values. New risk factors for 30-day mortality were investigated. Definite diagnosis for 120 eligible patients was made in 104 (86.7%) and 101 (84.2%) cases by TG07 and TG13, respectively (P = 0.36), higher than 61 (50.8%) by Charcot's triad (P < 0.001). Diagnostic overlap and concordance (κ) are 90.8% (109/120) and 0.63 (P < 0.0001). Patients classified into mild and moderate grades by TG07 and TG13 differed significantly (P = 0.043). Both guidelines could not predict clinical outcomes except the needs for multi ERCP session by TG13. Intrahepatic obstruction (OR = 11.2, 95% CI: 1.55-226.9) and hypoalbuminemia (≤ 25.0 g/l; OR = 17.3, 95% CI: 3.5-313.6) were independent risk factors for 30-day mortality in multivariate model. Two guidelines are reproducible and reliable in AC diagnosis but different in severity grading. TG13 are more practical for immediate severity grading, enabling planning treatment upon admission. Intrahepatic obstruction is a new candidate predictor of 30-day mortality for further assessment. © 2013 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

  15. [A study of Kyokan Gijuku: a supplement to the history of syphilis testing in Tokyo].

    Science.gov (United States)

    Nakanishi, Atsuo; Higuchi, Teruo

    2009-09-01

    The testing and treatment of licensed prostitutes for syphilis in the Tokyo area began around February 1872 (Meiji 5) within the Yoshiwara red-light district, surprisingly enough from the request of the brothels themselves. In 1876 (Meiji 9), an ordinance for the testing of licensed prostitutes for syphilis was passed, making testing and treatment mandatory, but little research has been done on the changes this brought about within the district in the intervening period. It is this interval of time that we have undertaken to examine, making use not only of laws, ordinances, and other public documents, but also manners and customs, incidents within the district, and sources from the hygiene police, among other materials. The results of our research into the four-and-a-half-year period beginning in May 1871 (Meiji 4) lead us to surmise that, due to three disastrous conflagrations, the district hit an economic dead end, and its syphilis testing activities were swallowed up by an officialdom bent on strengthening the hygienic police. Some of the physicians at the Kyokan Gijuku showed a subjective concern with syphilis testing at the Yoshiwara in its early stages, but they never carried out systematic education on the subject within the school.

  16. Insomnia as a sequela of sarin toxicity several years after exposure in Tokyo subway trains.

    Science.gov (United States)

    Kawada, Tomoyuki; Katsumata, Masao; Suzuki, Hiroko; Li, Qing; Inagaki, Hirofumi; Nakadai, Ari; Shimizu, Takako; Hirata, Kimiko; Hirata, Yukiyo

    2005-06-01

    More than 5,000 passengers on Tokyo subway trains were injured with toxic chemicals including the nerve gas "sarin" on March 20, 1995. The purpose of this study was to identify the effect of sarin exposure on insomnia in a cross-sectional study. A self-administered questionnaire concerning sleep-related items was distributed to victims of sarin exposure in October and November, 2003. Questionnaires were completed by 161 of the 163 participants (98.8%), who were selected from 1,500 subjects. Among them, the authors selected 75 women 30 to 69 years of age. Control participants were collected from inhabitants living in Maebachi City, Gunma Prefecture, Japan. For the younger exposed group (under 50 yr. of age), percentages of poor sleep, difficulty falling asleep, intermittent awakening, early morning awakening, a feeling of light overnight sleep, and insomnia were significantly higher than those for the control group. In contrast, the older exposed group (ages 50 to 69 years) had significantly higher prevalence of poor sleep, a feeling of light overnight sleep, and early morning awakening for the exposed group when compared with the control group. The high prevalence of insomnia and insomnia-related factors for victims especially under 50 years of age suggests a need for research on sleep quality after sarin exposure. Although posttraumatic stress disorder is assumed to be a psychological effect of exposure to a toxic substance, a cause-and-effect relationship has not been established.

  17. Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan; São Paulo, Brazil; and Hawaii, USA

    Science.gov (United States)

    Iwasaki, Motoki; Franke, Adrian A.; Hamada, Gerson Shigeaki; Miyajima, Nelson Tomio; Sharma, Sangita; Ishihara, Junko; Takachi, Ribeka; Tsugane, Shoichiro; Le Marchand, Loïc

    2015-01-01

    Objectives Previous studies of Japanese migrants have suggested that the increase in colorectal cancer rates occurring after migration is slower among Japanese Brazilians than Japanese Americans. We hypothesized that this difference may partly reflect differences in vegetable and fruit intake between populations. Methods Using data from validation studies of food frequency questionnaires being used in a comparative case-control study of colorectal adenoma in Tokyo, São Paulo, and Hawaii, plasma carotenoids, retinol, tocopherols, and coenzyme Q10 levels were measured by high-performance liquid chromatography, and 25-hydroxy vitamin D levels by enzyme-linked immunosorbent assay. Plasma levels were compared by analysis of covariance between 142 Japanese in Tokyo, 79 Japanese Brazilians in São Paulo, and 78 Japanese Americans in Hawaii. Results Overall, we found significantly lower plasma carotenoid levels, except for lycopene, and retinol levels in Japanese Americans than in Japanese in Tokyo and Japanese Brazilians. Plasma total carotenoids level was highest in Japanese Brazilians. Compared to mean level among Japanese Brazilians (1741.2 ng/mL), p for difference was 0.03 for Japanese in Tokyo (1514.4 ng/mL) and Tokyo than in Japanese Americans and Japanese Brazilians. Conclusion Higher levels of plasma carotenoids among Japanese Brazilians than Japanese in Tokyo and Hawaii may contribute to the slower pace of increase in colorectal cancer rates observed in that population following migration. PMID:25633435

  18. Necrosis avascular secundaria al tratamiento de la luxación congénita de cadera: relación entre factores terapéuticos y secuelas radiológicas

    OpenAIRE

    Burgos Flores, Jesús; Ocete Guzman, J. G.; González Herranz, P.; Angora Canego, R.; Amaya Alarcón, Santiago

    1993-01-01

    Se presentan 108 casos de Luxación Congénita de Cadera (LCC) unilateral tratados con la misma metódica terapéutica: tracción más reducción abierta o cerrada dependiendo de los hallazgos artrográficos. Tras un seguimiento medio de 7 años (Rango: 5-13), 5 (5%) tenían una coxa magna, 14 (13%) mostraban disminución de la altura epifisaria, 22 (20%) tenían una coxa magna con disminución de la altura epifisaria 10 (9%) presentaban lesión fisaria residual. El análisis estadístico demo...

  19. Detección de toxoplasmosis congénita en líquido amniótico humano mediante la técnica de nested-pcr

    Directory of Open Access Journals (Sweden)

    A. Hortúa

    2000-07-01

    Full Text Available La toxoplasmosis es provocada por el parasite intracelular obligado Toxoplasma gondii,de la familia Toxoplasmidae (Flores, 1991. Este parasite puede ser asintomático en adultos con un sistema inmune normal, pero puede ser de gran trascendencia en el feto en gestación y en pacientes con SIDA o deficiencia en el sistema inmune (Montoya, 1996. La presencia de anticuerpos antitoxoplasma indica únicamente que la persona se infecto con el microorganismo en un momento dado y no que haya oeste desarrollando la toxoplasmosis necesariamente, pero un resultado positivo indica que el individuo está en riesgo de desarrollar la enfermedad (Perea, 1983. \\ Si la infección se produce durante el embarazo, existe la posibilidad que la toxoplasmosis sea transmitida al feto ocasionando aborto espontaneo, prematuridad o enfermedades severas en el feto, tales como: hidrocefalia y calcificaciones inn-ace- i rebrales (Picazo, 1994. En la mayoría de los casos el diagnóstico biológico de la toxoplasmosis congénita se basa en métodos serológicos indirectos; sin embargo, en los últimos años los diversos estudios realizados en Biología Molecular permitieron utilizar la Técnica de Reacción en Cadena de la Polimerasa (PCR para el diagnóstico de la enfermedad (Hohlfeld, 1994. Los primeros estudios en PCR fueron dirigidos a la amplificación de la secuencia repetitiva del gen B1 de Toxoplasma gondii en líquido amniótico de mujeres infectadas (Grover, 1990. La prueba de PCR en liquido amniótico es definitivamente mas sensible que otras técnicas convencionales usadas, ya que estas presentan dificultad en establecer un diagnóstico segura y oportuno, por esto se ha implementando la técnica de PCR en la detección de la toxoplasmosis, aportando un progreso indiscutible en aquellos casos donde los exámenes clínicos y serológicos presentan limitaciones. También disminuye el tiempo de análisis de las muestras arrojando resultados en un período máximo de 24

  20. Ascitis en ausencia de edema: forma rara de inicio de la linfangiectasia intestinal congénita Ascites in absence of edema: a rare form of onset of congenital intestinal lymphangiectasis

    Directory of Open Access Journals (Sweden)

    Luis Francisco Martínez Cardet

    2005-06-01

    Full Text Available La linfangiectasia intestinal congénita, enteropatía perdedora de proteínas de aparición esporádica que afecta fundamentalmente a niños y adultos jóvenes, se inicia por lo general con edemas y diarreas. Mostramos el caso de un lactante que presentó ascitis en ausencia de edemas, así como los hallazgos clínicos, de laboratorio e histológicos y la respuesta al tratamiento con triglicéridos de cadena mediaCongenital intestinal lymphangiectasis, a protein-losing enteropathy that appears sporadically and affects mainly children and young adults, begins generally with edemas and diarrheas. The case of an infant that presented ascites in absence of edemas is presented. The clinical, laboratory and histological findings, as well as the response to the treatment with mean chain triglycerides are included in this paper

  1. Niveles de inmunoglobulinas IgA e IgM en recién nacidos y correlación con infección congénita

    OpenAIRE

    Rafael Ferrer Montoya; Alina de la C. Vázquez Estrada; Thorvald Fortún de Soto; Sara Ferrándiz Guerra

    1998-01-01

    Se realizó un estudio analítico y prospectivo en 600 recién nacidos, de los niveles sanguíneos de IgM e IgA y su relación con el riesgo de infección congénita. Se encontró elevada la IgM en 10 neonatos (1,7 %) y la IgA en 18 (3 %). Se halló una buena correlación (OR) y significancia estadística de IgM e IgA elevadas en los neonatos cuyas madres tuvieron líquido amniótico caliente y/o fétido, ruptura de las membranas de más de 24 horas y fiebre intraparto. También hubo una buena correlación (O...

  2. Síndrome de rubéola congénita en 6 colegios para niños con sordera y/o ceguera, en Lima, Cusco y Arequipa, Perú, 1998 - 2000

    OpenAIRE

    Blitchtein Winicki, Dora; Silva, Nazario; Narváez, Mario; Gonzáles, Jorge; Gonzáles, Maribel; Del Águila, Roberto; Suárez Ognio, Luis

    2013-01-01

    Objetivo: Deteminar la presencia de casos de síndrome de rubéola congénita (SRC) en tres ciudades del Perú. Diseño: Transversal, descriptivo. Material y métodos: En 6 colegios de educación especial para niños sordos y/o ciegos, ubicados en Lima (tres), Cusco (dos) y Arequipa (uno), se analizó la información contenida en registros médicos de niños menores de 12 años. Se incluyó los casos con criterios mayores de la definición de SRC. Resultados: De 364 registros de niños que estudian en colegi...

  3. INCIDÊNCIA DE MALFORMAÇÃO CONGÊNITA E ATENÇÃO EM SAÚDE NAS INSTITUIÇÕES DE REFERÊNCIA

    Directory of Open Access Journals (Sweden)

    Virgínia Rossana de Sousa Brito

    2010-01-01

    Full Text Available El objetivo fue identificar la incidencia de malformación congénita en instituciones de salud de renombre, el perfil social-demográfico de los padres, composición de los equipos de atención a la demanda, anotaciones referentes al acompañamiento del crecimiento/desarrollo de los niños. Estudio documental, cuantitativo, en cinco instituciones médicas de renombre. Se estudiaron 103 historiales médicos de niños con hasta diez años de edad, usándose dos formularios. Mayor incidencia del sexo masculino, Síndrome de Down, microcefalia, hidrocefalia, sordera. La mayoría de los equipos de notoriedad no está compuesta por todos los profesionales necesarios para la asisten- cia integral de los niños. El enfermero no consta en la composición de los equipos. El análisis del crecimiento/desarrollo fue inválido por falta de registro en los historiales médicos. El perfil social-demográfico de los padres de los niños se caracterizó por la diversidad de ingresos, edad y escolaridad. Las malformaciones señaladas en este resumen se sobreponen a las otras malformaciones congénitas, lo que constituye un problema de salud pública. Las referencias estudiadas tratan de satisfacer las necesidades de salud demandadas para desarrollar las habilidades psicomotoras.

  4. Decreasing trends of suspended particulate matter and PM2.5 concentrations in Tokyo, 1990-2010.

    Science.gov (United States)

    Hara, Kunio; Homma, Junichi; Tamura, Kenji; Inoue, Mariko; Karita, Kanae; Yano, Eiji

    2013-06-01

    In Tokyo, the annual average suspended particulate matter (SPM) and PM2.5 concentrations have decreased in the past two decades. The present study quantitatively evaluated these decreasing trends using data from air-pollution monitoring stations. Annual SPM and PM2.5 levels at 83 monitoring stations and hourly SPM and PM2.5 levels at four monitoring stations in Tokyo, operated by the Tokyo Metropolitan Government, were used for analysis, together with levels of co-pollutants and meteorological conditions. Traffic volume in Tokyo was calculated from the total traveling distance of vehicles as reported by the Ministry of Land, Infrastructure, Transport, and Tourism. High positive correlations between SPM levels and nitrogen oxide levels, sulfur dioxide levels, and traffic volume were determined. The annual average SPM concentration declined by 62.6%from 59.4 microg/m3 in 1994 to 22.2 microg/m3 in 2010, and PM2.5 concentration also declined by 49.8% from 29.3 microg/m3 in 2001 to 14.7 microg/m3 in 2010. Likewise, the frequencies of hourly average SPM and PM2.5 concentrations exceeding the daily guideline values have significantly decreased since 2001 and the hourly average SPM or PM2.5 concentrations per traffic volume for each time period have also significantly decreased since 2001. However SPM and PM2.5 concentrations increased at some monitoring stations between 2004 and 2006 and from 2009 despite strengthened environmental regulations and improvements in vehicle engine performance. The annual average SPM and PM2.5 concentrations were positively correlated with traffic volumes and in particular with the volume of diesel trucks. These results suggest that the decreasing levels of SPM and PM2.5 in Tokyo may be attributable to decreased traffic volumes, along with the effects of stricter governmental regulation and improvements to vehicle engine performance, including the fitting of devices for exhaust emission reduction.

  5. Characteristics of caffeine intoxication-related death in Tokyo, Japan, between 2008 and 2013.

    Science.gov (United States)

    Suzuki, Hideto; Tanifuji, Takanobu; Abe, Nobuyuki; Maeda, Masako; Kato, Yukihisa; Shibata, Mikiyoshi; Fukunaga, Tatsushige

    2014-10-01

    Caffeine is widely available in beverages and over-the-counter products; however, in large doses, it can lead to lethal arrhythmia. This study aims to clarify the characteristics of caffeine intoxication-related deaths in Tokyo, Japan. Among the 4754 forensic autopsy cases between 2008 and 2013 in which a toxicological investigation was performed, cases in which the blood concentration of caffeine exceeded toxic levels (15 μg/ml) were selected (N = 22). We examined subjects' ages, medical histories, direct/underlying causes of death, and manner of death. We also assessed concurrent drug substance detection and identified the origin of the caffeine. More than 60% of the subjects were between the ages of 20 and 49 years (n = 14, 63.6%). Sixteen cases (72.7%) showed a history of psychiatric diseases such as depression and sleep disorders. The underlying cause of death for all cases except two was caffeine intoxication, and manner of death was classified as undetermined (n = 11), accidental (n = 7), suicide (n = 2), or others (n = 2). Toxicological analysis revealed the presence of ingredients common to analgesics/cold remedies in 12 cases (54.5%). The origin of the caffeine was identified in 11 cases (50.0%); the proportion of identification was significantly lower among the cases in which analgesic/cold remedy ingredients were not detected (20.0%). Caffeine intoxication-related deaths mainly occurred in young and middle-aged persons with common psychiatric diseases. Psychiatrists should take note of caffeine dependence while diagnosing common psychiatric symptoms. In half of the cases, the origin of the caffeine was unidentified; nevertheless, dietary sources or over-the-counter drugs containing caffeine were suspected. As it becomes easier to obtain caffeinated products, continuous monitoring of the number of deaths from caffeine intoxication, in addition to detailed investigations of the caffeine's origin, will be necessary.

  6. Characteristics of Sudden Bath-Related Death Investigated by Medical Examiners in Tokyo, Japan

    Science.gov (United States)

    Suzuki, Hideto; Hikiji, Wakako; Tanifuji, Takanobu; Abe, Nobuyuki; Fukunaga, Tatsushige

    2015-01-01

    Background Sudden bath-related deaths occur frequently in Japan, particularly among elderly people. However, the precise mechanism of bath-related death remains uncertain, and effective prevention strategies have not been established. Methods Cases of bath-related deaths (n = 3289) were selected from all cases handled by the Tokyo Medical Examiner’s Office from 2009 to 2011 (N = 41 336). The ages and occurrence dates were examined, and major autopsy findings, including toxicological analysis, were evaluated for the autopsied cases (n = 550). Results Most cases occurred in individuals older than 60 years of age during winter. Analysis of autopsy findings revealed water inhalation signs in many cases (n = 435, 79.1%). Circulatory system diseases constituted more than half of the pathological findings regarding factors that may have contributed significantly to death (n = 300, 54.5%), and cardiac lesions were the most common pathological finding (n = 250, 45.5%). However, approximately one-third of the cases exhibited no remarkable pathological findings (n = 198, 36.0%). A quarter of all cases involved blood ethanol levels that exceeded 0.5 mg/mL (n = 140). Conclusions The results suggested that drowning plays an important role in the final process of bath-related death. Circulatory system diseases may be the primary underlying pathology; however, there were variations in the medical histories and pathologies of cases of bath-related death. From a preventive perspective, family members should pay attention to elderly people with circulatory system diseases during bathing, particularly in winter. Additionally, the notion that ill or inebriated individuals should not take baths should be reinforced. PMID:25503827

  7. Subsidy and parental attitudes toward pediatric health care in the Tokyo metropolitan area.

    Science.gov (United States)

    Higashi, Kenichi; Itoh, Mitsuko; Toyokawa, Satoshi; Kobayashi, Yasuki

    2016-02-01

    In Japan, the number of municipalities that offer free medical care for children has increased. This policy, however, might unintentionally aggravate the overcrowded situation of pediatric ambulatory services in Japan. We investigated the relationship between parents' health-care seeking attitudes according to child symptom severity and the amount of copayment, as well as parents' socioeconomic and demographic factors. We used data for 4385 people from the Japanese Study of Stratification, Health, Income and Neighborhood (J-SHINE), which consisted of stratified random sampling of those aged from 25 to 50 years who lived in Tokyo and neighboring areas. Outcome variables were respondent health-care seeking attitudes toward their children's mild and severe symptoms of cold. Logistic regression models were developed for each dependent variable. A total of 1606 respondents with one or more children under the age of 15 years were included in the analysis. For mild symptoms of cold, no subsidy (OR: 0.51, 95%CI: 0.38-0.69) and partial subsidy (OR, 0.71; 95%CI: 0.54-0.95) were associated with fewer "visit on that day" answers, compared with full subsidy. Income and respondent educational level were not associated with the outcome. For severe symptoms of cold, the OR of no subsidy (0.61; 95%CI: 0.30-1.23) and that of partial subsidy (0.91; 95%CI: 0.40-2.07) were not statistically significant. Imposing a small copayment might prevent visits to medical facilities for mild symptoms of cold, but will not prevent visits for severe symptoms of cold. © 2015 Japan Pediatric Society.

  8. Prevalence of Listeria monocytogenes in retailed meat in the Tokyo metropolitan area.

    Science.gov (United States)

    Ochiai, Yoshitsugu; Yamada, Fumiya; Batmunkh, Otgonchimeg; Mochizuki, Mariko; Takano, Takashi; Hondo, Ryo; Ueda, Fukiko

    2010-09-01

    This study was conducted to determine the prevalence of Listeria monocytogenes in retailed meats, comprising beef, chicken, and pork, in the Tokyo metropolitan area. A total of 379 samples of retailed meat were collected from 1998 to 2003, most of which were obtained by simultaneously purchasing the three classes of meat from a shop and then making another simultaneous purchase of meat from the same shop a few weeks later. The prevalence of L. monocytogenes was 28.0%, and the serotypes isolated were mainly 1/2a, 1/2b, 1/2c, and 4b. Comparison of the prevalence of each serotype among the classes of meat showed a predominant distribution of serotypes 1/2a, 1/2b, and 4b in chicken, while serotype 1/2c was dominant in pork. A total of nine cases considered to be due to persistence and/or cross-contamination were found. Most of the strains involved in persistence and/or cross-contamination were of serotypes 1/2c or 4b. These results suggest that contamination in retailed meat in Japan is at almost the same level as in other countries and that chicken has the highest potential as a source of contamination and infection. In addition, we suggest that the ecological niche of serotype 1/2c is distinct from those of 1/2a, 1/2b, and 4b, which may explain why human hosts have less opportunity to be exposed to serotype 1/2c and why there is a lower rate of isolation of this serotype from cases of human listeriosis.

  9. The demographic characteristics of medicolegal death among welfare recipients in Tokyo Metropolis (2008-2013).

    Science.gov (United States)

    Suzuki, Hideto; Tanifuji, Takanobu; Abe, Nobuyuki; Fukunaga, Tatsushige

    2017-04-01

    Background The number of welfare recipients has steadily increased in Japan during recent years, although the number of homeless persons has decreased. Despite there being many reports regarding medicolegal death among homeless persons, medicolegal death among welfare recipients has not been fully investigated. Methods We identified 10,293 individuals who received welfare aid during their lifetime among the 81,867 cases that were examined by the Tokyo Medical Examiner's Office (2008-2013). We retrospectively compared the proportions of medicolegal death to total population, age, sex, family status, clinical history, and manners/causes of death among non-indigent persons (controls), homeless persons, and welfare recipients. Results A higher proportion of medicolegal death to total population was observed among the welfare recipients, compared with the controls. The welfare recipients (65.5 years) were younger than the controls (68.9 years), and the proportions of male sex and living alone were higher among the welfare recipients. Hypertension and circulatory disease were the leading clinical conditions among the welfare recipients. Death due to disease was the leading manner of death, and circulatory disease was the leading cause of death among the welfare recipients. The proportion of individuals with a long period between death and discovery (which made determining the cause of death difficult) was also higher among the welfare recipients. Conclusion Welfare recipients have a greater risk of sudden death compared with non-indigent persons. Preventive strategies should target middle-aged to elderly men who live alone, and should address their risks of circulatory diseases and solitary death.

  10. Service hall in Number 1 Fukushima Nuclear Power Station, Tokyo Electric Power Company, Inc

    International Nuclear Information System (INIS)

    Tawara, Shigesuke

    1979-01-01

    There are six BWR type nuclear power plants in the Number 1 Fukushima Nuclear Power Station, Tokyo Electric Power Company, Inc. The service hall of the station is located near the entrance of the station. In the center of this service hall, there is the model of a nuclear reactor of full scale. This mock-up shows the core region in the reactor pressure vessel for the number one plant. The diameter and the thickness of the pressure vessel are about 5 m and 16 cm, respectively. The fuel assemblies and control rods are set just like the actual reactor, and the start-up operation of the reactor is shown colorfully and dynamically by pushing a button. When the control rods are pulled out, the boiling of water is demonstrated. The 1/50 scale model of the sixth plant with the power generating capacity of 1100 MWe is set, and this model is linked to the mock-up of reactor written above. The operations of a recirculating loop, a turbine and a condenser are shown by switching on and off lamps. The other exhibitions are shielding concrete wall, ECCS model, and many kinds of panels and models. This service hall is incorporated in the course of study and observation of civics. The good environmental effects to fishes and shells are explained in this service hall. Official buildings and schools are built near the service hall utilizing the tax and grant concerning power generation. This service hall contributes to give much freedom from anxiety to the public by the tour. (Nakai, Y.)

  11. Human resource development program for nuclear safety and security in Tokyo Institute of Technology

    International Nuclear Information System (INIS)

    Han, Chi Young; Sagara, Hiroshi; Nagasaka, Hideo

    2014-01-01

    The Academy for Global Nuclear Safety and Security Agent was established at Tokyo Institute of Technology in 2011, to develop global nuclear human resources in the field of 3S (Safety, Security, and Safeguards) as a Program for Leading Graduate Schools supported by MEXT (Ministry of Education, Culture, Sports, Science and Technology). New courses of nuclear safety and security were developed in addition to the existing nuclear engineering program; 1) Environmental Dynamics of Radioactive Nuclides; Numerical simulation of the environmental dispersion of radioactive materials released from hypothetical nuclear accidents and evaluation of the public exposure are performed, by using a computer-based emergency response system, to have students predict the environmental dispersion of radionuclides and radiological consequence by nuclear accidents. 2) Measurement of Environmental Radiation; Students acquire hands-on experiences measuring environmental radiation contamination caused by the nuclear accident in Fukushima with multiple types of radiation detectors. Environmental samples are collected and analyzed for isotope identification and its spatial distribution. 3) Simulation of Severe Nuclear Accidents; The evaluation results of Fukushima accident progression are discussed as well as typical sever accidents that threaten the integrity of reactor vessel. Students simulate BWR (Boiling Water Cooled Reactor) transients, design basis accidents, and severe accidents by using simulators. 4) Nuclear Security Training; Design of physical protection systems, its fundamental physics, and regulatory frameworks are covered and students gain the practical experiences by use of intrusion detection systems at JAEA (Japan Atomic Energy Agency), and by numerical simulation of hydro-dynamics of structure material and nuclear material criticality at the university. (author)

  12. Progression of Tokyo Guidelines and Japanese Guidelines for management of acute cholangitis and cholecystitis.

    Science.gov (United States)

    Mayumi, Toshihiko; Someya, Kazuki; Ootubo, Hiroki; Takama, Tatsuo; Kido, Takashi; Kamezaki, Fumihiko; Yoshida, Masahiro; Takada, Tadahiro

    2013-12-01

    The Japanese Guidelines for management of acute cholangitis and cholecystitis were published in 2005 as the first practical guidelines presenting diagnostic and severity assessment criteria for these diseases. After the Japanese version, the Tokyo Guidelines (TG07) were reported in 2007 as the first international practical guidelines. There were some differences between the two guidelines, and some weak points in TG07 were pointed out, such as low sensitivity for diagnosis and the presence of divergence between severity assessment and clinical judgment for acute cholangitis. Therefore, revisions were started to not only make them up to date but also concurrent with the same diagnostic and severity assessment criteria. The Revision Committee for the revision of TG07 (TGRC) performed validation studies of TG07 and new diagnostic and severity assessment criteria of acute cholangitis and cholecystitis. These were retrospective multi-institutional studies that collected cases of acute cholangitis, cholecystitis, and non-inflammatory biliary disease. TGRC held 35 meetings as well as international email exchanges with co-authors abroad and held three International Meetings. Through these efforts, TG13 improved the diagnostic sensitivity for acute cholangitis and cholecystitis, and presented criteria with extremely low false positive rates. Furthermore, severity assessment criteria adapted for clinical use, flowcharts, and many new diagnostic and therapeutic modalities were presented. The world's first management bundles of acute cholangitis and cholecystitis were also presented. The revised Japanese version was published with the same content as TG13. An electronic application of TG13 that can help to diagnose and assess the severity of these diseases using the criteria of TG13 was made for free download.

  13. Prevalence of avian haemosporidia among injured wild birds in Tokyo and environs, Japan

    Directory of Open Access Journals (Sweden)

    Mizue Inumaru

    2017-12-01

    Full Text Available Avian haemosporidia have been reported in various birds of Japan, which is part of the East Asian-Australian flyway and is an important stopover site for migratory birds potentially carrying new pathogens from other areas. We investigated the prevalence of avian malaria in injured wild birds, rescued in Tokyo and surrounding areas. We also evaluated the effects of migration by examining the prevalence of avian malaria for each migratory status. 475 birds of 80 species were sampled from four facilities. All samples were examined for haemosporidian infection via nested polymerase chain reaction (PCR of the cytochrome b (cytb gene. 100 birds (21.1% of 43 species were PCR positive for avian haemosporidia. Prevalence in wintering birds, migratory breeders, and resident birds was 46.0%, 19.3%, 17.3% respectively. There was a bias in wintering birds due to Eurasian coot (Fulica atra and Anseriformes. In wintering birds, lineages which are likely to be transmitted by Culiseta sp. in Northern Japan and lineages from resident species of Northern Japan or continental Asia were found, suggesting that wintering birds are mainly infected at their breeding sites. Meanwhile, there were numerous lineages found from resident and migratory breeders, suggesting that they are transmitted in Japan, some possibly unique to Japan. Although there are limits in studying rescued birds, rehabilitation facilities make sampling of difficult-to-catch migratory species possible and also allow for long-term monitoring within areas. Keywords: Avian haemosporidia, Japan, Rescued wild birds, Migratory birds, Parasite diversity, Cytochrome b

  14. Medicolegal death of homeless persons in Tokyo Metropolis over 12 years (1999-2010).

    Science.gov (United States)

    Suzuki, Hideto; Hikiji, Wakako; Tanifuji, Takanobu; Abe, Nobuyuki; Fukunaga, Tatsushige

    2013-05-01

    Recently, the number of homeless persons in Japan has steadily decreased. However, it is not certain whether unexpected death of the homeless have actually decreased in proportion to decrease in total number of cases. The documentation of medicolegal deaths among homeless persons handled in the Tokyo Medical Examiner's Office during 1999-2010 were reviewed, and we compared the number and manner/cause of death between cases occurring before 2004 and those occurring after 2004. In addition, we compared manner/cause of death between homeless and non-homeless persons. The number of medicolegal deaths of homeless persons remained almost the same during the study period in spite of a marked decrease in the total number of homeless persons after 2004. Age distribution shifted to older after 2004, and a higher proportion of the deceased had longer postmortem periods after 2004. Comparison between the manners/causes of death of the cases occurring before 2004 and those occurring after 2004 showed little difference. Disease constituted about 70% of all cases, and causes of death from disease were more various than those of non-homeless persons. Certain specific patterns included a higher proportion of death from circulatory disease in elderly homeless persons and a higher proportion of death from alcohol-related digestive disease and tuberculosis among younger homeless persons. Regarding accidental death, hypothermia was a leading cause of death irrespective of age group. Aging and isolation among homeless persons might contribute to an unchanged number of medicolegal death of them. In addition to measures to address frequent causes of death in each age group, better intervention for isolated homeless persons might be a key factor to prevent unexpected deaths of homeless persons in the future. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  15. Accelerator mass spectrometry at the University of Tokyo and its applications

    International Nuclear Information System (INIS)

    Matsuzaki, Hiroyuki

    2003-01-01

    In accelerator mass spectrometry (AMS), the sample to be analyzed itself is accelerated to form ion beams, and mass spectrometry is applied. Particularly with AMS, a very small amount of long half-life radioactive isotope can be measured with extremely high sensitivity. As the example of AMS measurement, this study firstly took up the measurement of 14 C, which is the most widely used as a probe for dating, as well as the measurement of 10 Be and 26 Al as examples. Then, it described the outline of AMS measurement using a tandem type electrostatic accelerator, which has many advantageous features for AMS. Today, tandem type electrostatic accelerator is used in AMS measurement in most cases. Finally, this paper reviewed the macro analysis laboratory tandem (MALT) accelerator of the Atomic Energy Research Center, University of Tokyo. The accelerator is pelletron type and acceleration voltage is maximum 5 MV. It is No. 1 unit that the USA NEC Corporation designed with consciousness of AMS. The incident analysis system is equipped with a sequential injection system that allows ions of different masses to be injected alternately, and the analysis system on the high energy side is equipped with a multi-Faraday cup system. At MALT, in addition to 14 C - AMS, routine measurements of 10 Be - AMS, 26 Al - AMS that are unique in Japan are carried out. In addition, MALT has multiple beam courses, and conducts the ultrafine analysis of elements using the methods other than AMS, as well as accelerator analysis research such as basic scientific experiments. (A.O.)

  16. Interim report on the accident at Fukushima Nuclear Power Stations of Tokyo Electric Power Company

    International Nuclear Information System (INIS)

    2011-12-01

    The Investigation Committee on the Accident at the Fukushima Nuclear Power Stations (the Investigation Committee) of Tokyo Electric Power Company (TEPCO) was established by the Cabinet decision on May 24, 2011. Its objectives are: to conduct investigation for finding out the causes of accidents at the Fukushima Dai-ichi Nuclear Power Station (Fukushima Dai-ichi NPS) and Fukushima Dai-ni Nuclear Power Station (Fukushima Dai-ni NPS) of TEPCO as well as the causes of accident damage; and to make policy recommendations for limiting the expansion of damage and preventing reoccurrence of similar accidents. The Investigation Committee has conducted its investigation and evaluation since its first meeting on June 7, 2011. Its activities included: site visits to the Fukushima Dai-ichi and Dai-ni NPSs, as well as to other facilities; hearing of heads of local governments around the Fukushima Dai-ichi NPS; and hearing of people concerned through interviews mainly arranged by the Secretariat. As of December 16, 2011, the number of interviewees reached 456. The investigation and evaluation by the Investigation Committee are still ongoing and the Interim Report does not cover every item that the Committee aims at investigating and evaluating. Fact-finding of even some of those items discussed in the Interim Report are not yet completed. The Investigation Committee continues to conduct its investigation and evaluation and will issue its Final Report in the summer of 2012. This brief executive summary covers mainly considerations and evaluation of the issues in Chapter VII of the Interim Report, with brief reference to Chapters I to VI. The Investigation Committee recommendations are printed in bold. (author)

  17. Impact of subsidies and socioeconomic status on varicella vaccination in Greater Tokyo, Japan

    Directory of Open Access Journals (Sweden)

    Kei eNagaoka

    2016-03-01

    Full Text Available Background: Although the control of varicella outbreaks is an important health issue, cost could present a major barrier for vaccination The aim of this study is to investigate the association of vaccine subsidies and caregivers’ socioeconomic status with varicella vaccine coverage of their children in Greater Tokyo, Japan, before the period that varicella vaccination was included as routine immunization program.Methods: Participants were recruited from two different cities. In Chiba city, parents of 18-month-old infants (N = 378 undergoing a medical examination in July 2013 were recruited at a clinic where no subsidy for varicella immunization was provided. In Nishitokyo city, parents of 24- to 30-month-old children (N=315 undergoing a health check-up in July and August 2013 were recruited at a clinic where a partial subsidy was provided. The association between household income and varicella immunization was investigated by multivariate logistic regression stratified by city.Results: Vaccine coverage was 61.0% in Chiba city and 73.3% in Nishitokyo city. In Chiba city, odds ratios of middle and high household income for varicella immunization were 4.22 (95% CI (confidence interval: 1.65-10.7 and 5.94 (95% CI: 1.89-18.6 compared to low household income, respectively. However, household income was not associated with varicella vaccination in Nishitokyo city. Neither working status nor education was associated with vaccination in both cities. Conclusions: While household income was associated with high vaccine coverage in the city with no vaccine subsidy, this association was not observed in the city where the subsidy was given, which suggests that cost is a barrier for varicella immunization.Thus, in countries where varicella vaccination is not included in routine immunization program, introducing subsidies nationwide or routine immunization programs for varicella vaccination would be an important approach to eliminate inequality in vaccine

  18. [Two Outbreaks of Yersinia enterocolitica O:8 Infections in Tokyo and the Characterization of Isolates].

    Science.gov (United States)

    Konishi, Noriko; Ishitsuka, Rie; Yokoyama, Keiko; Saiki, Dai; Akase, Satoru; Monma, Chie; Hirai, Akihiko; Sadamasu, Kenji; Kai, Akemi

    2016-01-01

    Although the number of outbreaks caused by Yersinia enterocolitica has been very small in Japan, 4 outbreaks were occurred during the 2 years between 2012 and 2013. We describe herein 2 outbreaks which were examined in Tokyo in the present study. Outbreak 1: A total of 39 people (37 high school students and 2 staff) stayed at a hotel in mountain area in Japan had experienced abdominal pain, diarrhea and fever in August, 2012. The Y. enterocolitica serogroup O:8 was isolated from 18 (64.3%) out of 28 fecal specimens of 28 patients. The infection roots could not be revealed because Y. enterocolitica was not detected from any meals at the hotel or its environment. Outbreak 2: A total of 52 students at a dormitory had diarrhea and fever in April, 2013. The results of the bacteriological and virological examinations of fecal specimens of patients showed that the Y. enterocolitica serogroup O:8 was isolated from 24 fecal specimens of 21 patients and 3 kitchen staff. We performed bacteriological and virological examination of the stored and preserved foods at the kitchen of the dormitory to reveal the suspect food. For the detection of Y. enterocolitica, food samples. together with phosphate buffered saline (PBS) were incubated at 4 degrees C for 21 days. Then, a screening test for Y. enterocolitica using realtime-PCR targeting the ail gene was performed against the PBS culture. One sample (fresh vegetable salad) tested was positive on realtime-PCR. No Y. enterocolitica was isolated on CIN agar from the PBS culture because many bacteria colonies other than Y. enterocolitica appeared on the CIN agar. After the alkaline-treatments of the culture broth or the immunomagnetic beads concentration method using anti-Y. enterocolitica O:8 antibodies, Y. enterocolitica O:8 which was the same serogroup as the patients' isolates was successfully isolated from the PBS culture. The fresh vegetable salad was confirmed as the incrimination food of this outbreak.

  19. Older Adults Looking for a Job through Employment Support System in Tokyo.

    Directory of Open Access Journals (Sweden)

    Ushio Minami

    Full Text Available This study aims to clarify the job seeking process of the elderly people through the local employment support facility known as the Active Senior Employment Support Center (ASESC"AKUTIBU SINIA SHUGYO SIEN SENTAA" in the Tokyo metropolitan area, and evaluate the performance as a complement to the national support systems.We conducted 6 waves of longitudinal mail surveys over 38 weeks to 235 older job seekers (146 males and 89 females, average age 63.7, SD 5.6, who visited two ASESCs for the first time, to clarify their living situation, health condition, and changes in their job seeking process.These older job seekers tended to be at a relatively low education level and on low income, as well as tended to seek jobs for earning living expenses rather than for well-being. Half of them found employment in 35.0 days; however, 23.8% couldn't find any job in 38 weeks, especially those who were younger and with higher education.ASESCs are functioning to assist older job seekers who are mainly seeking jobs for earning living expenses, which can be attained in a short time span and enable them to earn some money. These facilities are expected to be consulting services, not only for employment support but also for general living, because it is important to maintain contact with people who are at risk of social isolation, serious financial difficulty, or suicide. We consider it very helpful to encourage and re-activate these mismatched people, by supporting them to engage in highly contributional services to our society and the next generation, such as providing child-care support or daily life support, the demands for which are rapidly increasing due to recent governmental policies.

  20. Applicability of the prehospital termination of resuscitation rule in an area dense with hospitals in Tokyo: a single-center, retrospective, observational study: is the pre hospital TOR rule applicable in Tokyo?

    Science.gov (United States)

    Fukuda, Tatsuma; Ohashi, Naoko; Matsubara, Takehiro; Doi, Kent; Gunshin, Masataka; Ishii, Takeshi; Kitsuta, Yoichi; Nakajima, Susumu; Yahagi, Naoki

    2014-02-01

    It is unclear whether the prehospital termination of resuscitation (TOR) rule is applicable in specific situations such as in areas extremely dense with hospitals. The objective of the study is to assess whether the prehospital TOR rule is applicable in the emergency medical services system in Japan, specifically, in an area dense with hospitals in Tokyo. This study was a retrospective, observational analysis of a cohort of adult out-of-hospital cardiopulmonary arrest (OHCA) patients who were transported to the University of Tokyo Hospital from April 1, 2009, to March 31, 2011. During the study period, 189 adult OHCA patients were enrolled. Of the 189 patients, 108 patients met the prehospital TOR rule. The outcomes were significantly worse in the prehospital TOR rule-positive group than in the prehospital TOR-negative group, with 0.9% vs 11.1% of patients, respectively, surviving until discharge (relative risk [RR], 1.11; 95% confidence interval [CI], 1.03-1.21; P = .0020) and 0.0% vs 7.4% of patients, respectively, discharged with a favorable neurologic outcome (RR, 1.08; 95% CI, 1.02-1.15; P = .0040). The prehospital TOR rule had a positive predictive value (PPV) of 99.1% (95% CI, 96.3-99.8) and a specificity of 90.0% (95% CI, 60.5-98.2) for death and a PPV of 100.0% (95% CI, 97.9-100.0) and a specificity of 100.0% (95% CI, 61.7-100.0) for an unfavorable neurologic outcome. This study suggested that the prehospital TOR rule predicted unfavorable outcomes even in an area dense with hospitals in Tokyo and might be helpful for identifying the OHCA patients for whom resuscitation efforts would be fruitless. © 2013.

  1. The impact of the Great East Japan earthquake on mandatory psychiatric emergency hospitalizations in Tokyo: a retrospective observational study.

    Science.gov (United States)

    Aoki, A; Aoki, Y; Harima, H

    2012-10-09

    On 11 March 2011, the eastern part of Japan was struck by a magnitude 9.0 quake. About 20 000 people were killed or were missing, and a nuclear crisis followed. In Tokyo, people were indirectly exposed to the earthquake and nuclear crisis by TV broadcast. The aim of our study was to evaluate the potential effect of the series of catastrophes on psychiatric emergency hospitalizations in Tokyo. Clinical records of patients who were mandatorily admitted to Tokyo Metropolitan Matsuzawa Hospital by law because of urgent risk to self or others were reviewed. Records regarding the 2 years of investigation, which include the 6 months after the earthquake, were reviewed. The six months after the earthquake were compared with the eighteen months before the earthquake in clinical and demographic data using independent t-tests or χ(2) tests. During the 6 months before and after the earthquake, 97 and 127 people were mandatorily admitted. χ(2) Tests demonstrated a significant increase in the number of patients after the earthquake (P = 0.045), attributable to the significant increase in the number of patients with schizophrenia after the earthquake (P = 0.011, 32 vs 56), whereas there were no significant differences in the number of patients with other diagnoses between those two periods. Independent t-tests revealed that patients admitted after the earthquake had marginally significantly shorter periods of education compared with those admitted before the earthquake (13.78 vs 12.82 years, P = 0.084). This work suggests that patients with schizophrenia were more sensitive to indirect exposure to the earthquake and that a shorter period of education was a potential risk factor.

  2. [Serial Food Poisoning Outbreaks Caused by Norovirus-Contaminated Shredded Dried Laver Seaweed Provided at School Lunch, Tokyo, 2017].

    Science.gov (United States)

    Somura, Yoshiko; Kimoto, Kana; Oda, Mayuko; Okutsu, Yuta; Kato, Rei; Suzuki, Yasunori; Siki, Dai; Hirai, Akihiko; Akiba, Tetsuya; Shinkai, Takayuki; Sadamasu, Kenji

    2017-01-01

    In February 2017, four food poisoning outbreaks occurred in Tokyo, involving ten schools. Shredded dried laver seaweed processed by a single food manufacturer in December 2016 was provided in common for the school meals that caused all four outbreaks. Of 4,209 persons exposed, 1,193 (28.3%) had symptoms of gastroenteritis. Norovirus (NoV) GII was detected in 207 (78.1%) of 265 cases by real-time RT-PCR. Thirty-one shredded dried laver seaweed samples were examined and seven (22.6%) of them were positive for NoV GII. PCR fragments of NoV ORF1/2 junction region (302 bp) from seven shredded dried laver seaweed samples and 20 clinical samples derived from the four outbreaks were sequenced. All of them displayed complete homology, and the genotype was classified as GII.17. A nearly full-length sequence (7,420 bp) of NoV RNA derived from a case was obtained by next-generation sequencer analysis and phylogenetic analysis indicated that this strain belongs to the same cluster as Hu/GII/JP/2015/GII.P17_GII.17/Kawasaki308. Thus, our investigation elucidated that the causative agent of these four serial food poisoning outbreaks was NoV GII.17 and the infectious source was a single batch of shredded dried laver seaweed. The water activity of the shredded dried laver seaweed was found to be 0.119 to 0.129. It was epidemiologically clarified that NoV does not lose infectivity for about two months even in the dry state. We conclude that a large diffuse outbreak of food poisoning caused by NoV GII.17 contamination of shredded dried laver seaweed had occurred in Tokyo. Our elucidation of the causative agent indicated that the food poisoning outbreaks in multiple areas of Japan, including Tokyo, during January to February 2017 were caused by the same contaminated food.

  3. Does the Tokyo guidelines predict the extent of gallbladder inflammation in patients with acute cholecystitis? A single center retrospective analysis.

    Science.gov (United States)

    Ambe, Peter C; Christ, Hildegard; Wassenberg, Dirk

    2015-10-20

    The Tokyo guidelines provide criteria for the diagnosis and classification of acute cholecystitis in three severity grades. However, no data exists on the predictive value of these guidelines. The aim of this study was to analyze the accuracy of the Tokyo guidelines as a predicting parameter for the severity of acute cholecystitis in patients undergoing laparoscopic cholecystectomy. A retrospective analysis of the charts of patients undergoing laparoscopic cholecystectomy for acute cholecystitis in a primary care hospital within a five-year period was performed. The preoperative severity grades were compared with the histological extent of inflammation. One hundred thirty-eight patients; 79 with severity grade I, 33 with grade II and 26 with grade III were analyzed. The incidence of uncomplicated cholecystitis decreased with increasing severity grade, while the incidence of complicated cholecystitis increased with increasing severity. However, complicated cholecystitis was evident in an unexpectedly high number of cases with severity grade I. There was a significant correlation (χ (2)(1) = 10. 43, p = 0.01) between the preoperative severity grade and the extent of gallbladder inflammation on histopathology. Conversion to open surgery (14 vs. 5, p = 0.002) and complications (17 vs. 7, p = 0.001) were significantly higher in patients with preoperative severity grade II/III compared to patients with severity grade I. Worsening clinical severity correlated significantly with worseing pathology, findings from blood test and clinical outcomes; rates of conversion and morbidity. However, the Tokyo guidelines may have a tendency to underestimate the extent of inflammation in male patients with severity grade I and over estimate the difficulty of dissection in severity grade II.

  4. Fine-particulate Air Pollution from Diesel Emission Control and Mortality Rates in Tokyo: A Quasi-experimental Study.

    Science.gov (United States)

    Yorifuji, Takashi; Kashima, Saori; Doi, Hiroyuki

    2016-11-01

    Evidence linking air pollution with adverse health outcomes is accumulating. However, few studies have adopted a quasi-experimental design to evaluate whether decline in air pollution from regulatory action improves public health. We evaluated the effect of a diesel emission control ordinance introduced in 2003 on mortality rates in 23 wards of the Tokyo metropolitan area, Japan, from October 2000 to September 2012, taking into account change in mortality rates in a reference population (Osaka) with a introduction of such a regulation in 2009. We obtained daily counts of all-cause and cause-specific mortality and concentrations of nitrogen dioxide (NO2) and particulate matter less than 2.5 μm in diameter (PM2.5) during the study period. We employed interrupted time-series analysis to analyze the data. Decline in NO2 during the study period was similar in the two areas, while decline in PM2.5 and the improvement in age-standardized mortality rates were greater in Tokyo's 23 wards compared with Osaka. Even after adjusting for age-standardized mortality rates in Osaka, percent changes in mortality between the first 3-year interval (October 2000 to September 2003) and the last 3-year interval (October 2009 to September 2012) were -6.0% for all causes, -11% for cardiovascular disease, -10% for ischemic heart disease, -6.2% for cerebrovascular disease, -22% for pulmonary disease, and -4.9% for lung cancer. We did not observe a decline in mortality from other causes. This quasi-experimental study in Tokyo suggests that emission control was associated with improvements in both air quality and health outcomes.

  5. Effect of water temperature on survival of early-life stages of marbled flounder Pseudopleuronectes yokohamae in Tokyo Bay, Japan.

    Science.gov (United States)

    Lee, Jeong-Hoon; Kodama, Keita; Oyama, Masaaki; Shiraishi, Hiroaki; Horiguchi, Toshihiro

    2017-07-01

    We investigated factors that might have disturbed the stock recovery of marbled flounder in Tokyo Bay by focusing on the early life stages. Field surveys in Tokyo Bay from 2006 to 2011 revealed that mature adult biomass increased from 2006 to 2008 and decreased thereafter. Meanwhile, larval and juvenile densities were high in 2006 and 2008 but low in other years. Discrepancies in the yearly trends of these parameters suggest that mortality during life stages between spawning and early larval phases might have affected the abundance of the subsequent life stages. Monthly mean water temperature between January and February, in which hatching and pelagic larvae occur in the bay, was lower in 2006 (8.6 °C) and 2008 (9.6 °C) than was observed in other years (10.4-11.4 °C). Significant negative correlation between water temperature and larval density implies that mortality during pre- and post-larval stages would be higher in warmer winter years (>10 °C). To test this hypothesis, we examined the effects of water temperature on mortality and development in egg and larval stages under controlled laboratory conditions. Hatching rate was high in a water temperature range of 9.2-12.7 °C (66.6-82.5%), whereas it decreased in cooler (3.7% at 5.9 °C) or warmer (33.9% at 14.8 °C) conditions. Meanwhile, days from fertilization to hatching, size of larvae at hatching and survival rate of larvae after 18 d from hatching were monotonically and significantly decreased as water temperature was elevated. Combined evidence of the field and laboratory studies suggests that a warmer reproductive season (>10 °C) might induce mortalities of marbled flounder larvae in Tokyo Bay. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Consumo de oxígeno en hipotermia, durante circulación extracorpórea, en cirugías de niños con cardiopatías congénitas complejas en Canarias: perfiles cinéticos e implicaciones fisiológicas

    OpenAIRE

    García Mendieta, Jorge Saúl

    2016-01-01

    Programa de doctorado: Avances en Medicina Interna. La fecha de publicación es la fecha de lectura [ES]El presente estudio intenta demostrar que hay diferentes perfiles cinéticos de la relación consumo de oxígeno y temperatura corporal, durante la circulación extracorpórea e hipotermia (CEC-Hp) en niños operados por cardiopatías congénitas complejas en Canarias.

  7. Structure and dynamics of highly charged heavy ions studied with the electron beam ion trap in Tokyo

    International Nuclear Information System (INIS)

    Nakamura, Nobuyuki; Hu, Zhimin; Watanabe, Hirofumi; Li, Yueming; Kato, Daiji; Currell, Fred J.; Tong Xiaomin; Watanabe, Tsutomu; Ohtani, Shunsuke

    2011-01-01

    In this paper, we present the structure and the dynamics of highly charged heavy ions studied through dielectronic recombination (DR) observations performed with the Tokyo electron beam ion trap. By measuring the energy dependence of the ion abundance ratio in the trap at equilibrium, we have observed DR processes for open shell systems very clearly. Remarkable relativistic effects due to the generalized Breit interaction have been clearly shown in DR for highly charged heavy ions. We also present the first result for the coincidence measurement of two photons emitted from a single DR event.

  8. Difference in concentration trends of airborne particulate matter during rush hour on weekdays and Sundays in Tokyo, Japan.

    Science.gov (United States)

    Hara, Kunio; Homma, Junichi; Tamura, Kenji; Inoue, Mariko; Karita, Kanae; Kondo, Yoshinori; Yano, Eiji

    2014-09-01

    Suspended particulate matter (SPM) and fine particulate matter (less than or equal to 2.5 microm: PM2.5) have generally been decreasing for the last decade in Tokyo, Japan. To elucidate the major cause of this decrease, the authors investigated the different trends of airborne particulates (both SPM and PM2.5 concentrations) by evaluating comparisons based on the location of the monitoring stations (roadside vs. ambient), days of the week (weekdays vs. Sundays), and daily fluctuation patterns (2002 vs. 2010). Hourly mean SPM and PM2.5 concentrations were obtained at four monitoring stations (two roadside stations, two ambient stations) in Tokyo, Japan. Annual mean concentrations of each day of the week and of each hour of the day from 2002 to 2010 were calculated. The results showed that (1) the daily differences in annual mean concentration decreased only at the two roadside monitoring stations; (2) the high hourly mean concentrations observed on weekdays during the daily rush hour at the two roadside monitoring stations observed in 2002 diminished in 2010; (3) the SPM concentration that decreased the most since 2002 was the PM2.5 concentration; and (4) the fluctuation of hourly concentrations during weekdays at the two roadside monitoring stations decreased. A decreasing trend of airborne particulates during the daily rush hour in Tokyo, Japan, was observed at the roadside monitoring stations on weekdays since 2002. The decreasing PM2.5 concentration resulted in this decreasing trend of airborne particulate concentrations during the daily rush hours on weekdays, which indicates fewer emissions were produced by diesel vehicles. Implications: The authors compared the trends of SPM and PM2.5 in Tokyo by location (roadside vs. ambient), days of the week (weekdays vs. Sundays), and daily fluctuation patterns (2002 vs. 2010). The high hourly mean concentrations observed at the roadside location during rush hour on weekdays in 2002 diminished in 2010. The SPM

  9. Incidencia y tratamiento de las cardiopatías congénitas en San Miguel del Padrón Incidence and treatment of congenital heart disease in San Miguel del Padrón

    Directory of Open Access Journals (Sweden)

    Emilia Vega Gutiérrez

    2012-09-01

    Full Text Available Introducción: los defectos congénitos cardiovasculares son en la actualidad con frecuencia, la causa de muerte en los primeros años de vida, y la detección de estos en la etapa fetal, les proporciona a los futuros padres, los conocimientos que les permite tomar una decisión, con respecto a continuar o no con el embarazo. Objetivo: analizar la incidencia y tratamiento de las cardiopatías congénitas, en el municipio San Miguel del Padrón, en el periodo entre enero de 2007 y diciembre de 2010. Métodos: se realizó un estudio descriptivo acerca del diagnóstico prenatal y postnatal de las cardiopatías congénitas, en el municipio San Miguel del Padrón, entre el 1ro de enero de 2007 y el 31 de diciembre de 2010. Se detectó un total de 65 cardiopatías congénitas. Se aplicó una encuesta a las madres y familiares de 59 casos -por ser estos los que se encontraban residiendo en el área- para relacionar su etiología con factores de riesgos genéticos y ambientales. Además, se investigó el criterio individual acerca del manejo de estas por el servicio de genética, así como el grado de satisfacción y utilidad con respecto al asesoramiento genético. Resultados: esta investigación demostró una vez más, que las cardiopatías congénitas se mantienen dentro de las primeras causas de mortalidad infantil. Su incidencia en eeste estudio, se debió a factores ambientales de origen materno, entre los que se destacó el uso de teratógenos, principalmente el alcohol y el déficit de vitaminas y minerales. El asesoramiento genético recibido constituyó 54 (91 % casos una gran ayuda para las familias, las cuales consideraron necesaria esta especialidad, para mejorar la calidad de la atención médica. Conclusiones: las cardiopatías congénitas mostraron una alta incidencia en nuestro estudio en la etapa prenatal y postnatal. Las cardiopatías complejas constituyeron aproximadamente más de la mitad de los diagnósticos ecográficos antes del

  10. Patients' demographics of a convenient clinic located in a large railway station in metropolitan Tokyo area.

    Science.gov (United States)

    Tsuda, Kenji; Tanimoto, Tetsuya; Sakaue, Saori; Sato, Tomohiko; Kouno, Kaduki; Hamaki, Tamae; Hosoda, Kazutaka; Ohnishi, Mutsuko; Komatsu, Tsunehiko; Kami, Masahiro; Kusumi, Eiji

    2018-01-01

    Hidden barriers to visit a medical facility especially for young busy workers have been neglected in the aging society. The aim of this cross-sectional study is to analyze demographics of patients who had visited the first known convenient clinic located inside a railway station, which is adjusted to the lifestyle of working generations.We analyzed de-identified data of patients who had visited the department of internal medicine of a clinic, which is located inside a railway station building and offers primary care with after-hours accessibility in Tokyo, between August 2013 and June 2016. Data were collected on patients' sex, age, time of visit, waiting time, presence or absence of an appointment, diagnosis, and patients' addresses using the electronic health and billing records.Overall, 28,001 patients visited 87,126 times. Number of visits increased in winter season compared with the other seasons. Sixty-one percent were women and the median age of all patients was 38 years (range, 0-102). The number of visits on Mondays was the highest in a week and the most frequent visiting time was between 6 and 7 p.m. The number of visits of working generations (from 15 to 65 years old) and men increased after 6 p.m. and on weekends. The 3 most common diagnoses were upper respiratory tract infection (22,457), allergic rhinitis (20,916), and hypertension (4869). The number of individuals who were referred to other medical institutions was 1022 (1.2%). The median waiting time was 748 seconds (range, 2-5344). The number of visits from within 2-, 5-, and 10-mile radius from our clinic was 41,696 (50.6%), 63,190 (76.7%), and 75,015 (91.1%), respectively, and patients' addresses were mainly located along the railway network.The locational and temporal convenience of our clinic has attracted the unmet medical demands especially for young workers who have difficulty in visiting conventional medical institutions. Copyright © 2017 The Authors. Published by Wolters Kluwer Health

  11. Environmental control of short-term variation in the plankton community of inner Tokyo Bay, Japan

    Science.gov (United States)

    Nakane, Toru; Nakaka, Kisaburo; Bouman, Heather; Platt, Trevor

    2008-07-01

    Water temperature, salinity, nutrient concentrations and the composition of the plankton community were recorded at three stations in inner Tokyo Bay over a period of 328 days (from June 8, 1995 to April 30, 1996) with a nominal sampling frequency of once per day. Inspection of the results revealed that the data could be divided into two blocs as an aid to analysis: the period from June to October was characterized by the development of stratification of temperature and salinity (stratification period), and November to March was characterized by uniform temperature and salinity in the water column due to vertical mixing (mixing period). Oxygen-depleted water forms in the bottom layer during the stratification period, but vertical mixing of the water column, due to changing wind and rainfall conditions caused by passing weather fronts, results in the breakdown of the oxygen-depleted water mass. Nutrient loads are high in the surface water due to the freshwater supply, but occasional pulses of primary production cause a depletion of phosphate in the surface water, suggesting that the phosphorus becomes a limiting nutrient for phytoplankton growth in this period. Several short-term peaks of plankton abundance (blooms) occurred as responses to temporal changes in water quality from June to November, with consequent species succession. Significant fluctuations in the densities of the diatom Skeletonema costatum and several species of ciliates corresponded to the daily changes in the physical and chemical characteristics of the coastal environment. During the mixing period, when water temperature and solar radiation decreased, there were no short-term variations in water quality and although nutrient concentrations gradually increased from November to February, primary production remained low. This study shows that the short-term dynamics of the phytoplankton community are closely coupled to fluctuations in environmental forcing, and that the degree of coupling is

  12. [Prevalence of psychiatric disorders among homeless people in one area of Tokyo].

    Science.gov (United States)

    Morikawa, Suimei; Uehara, Ritei; Okuda, Kouzhi; Shimizu, Hiroko; Nakamura, Yosikazu

    2011-05-01

    This study is the first ever field survey in Japan of the prevalence of psychiatric disorders among homeless people in one area of Tokyo. The main aim of was to make accurate diagnoses by a psychiatrist to give an accurate picture. The survey period was from December 30, 2008 to January 4, 2009. The people covered by the survey were people living on the streets within a one-kilometer radius ofJR Ikebukuro Station in this period. The survey area was selected within Toshima City as a district where it would be possible to roughly grasp the total number of homeless people. The definition of homeless people in this study was the same as that which was stipulated in the Ministry of Health, Labor and Welfare national survey. A total of 115 people living on the streets received the written request to participate in the survey and 80 agreed to do so, beiung enrolled as the subjects of this study. Mini International Neuropsychiatric Interview (MINI) questionnaires and a separately created questionnaire that asked about the subjects' living circumstances were used in the interviews and finally, a psychiatrist made diagnoses of psychiatric disorders according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) diagnosis standards. The average age of the subjects was 50.5 (standard deviation; 12.3) and there were 75 men (93.8%) and 5 women (6.3%). 50 people (62.5%) were diagnosed with psychiatric disorders which included 33 people (41.3%) who had depression, 12 (15%) who were dependent on alcohol and 12 (15%) who had psychotic disorders such as hallucinations or delusions. Using the degree of risk in the MINI classification, 45 (57.0%) were at risk of committing suicide and 25 people (31.6%) had already attempted suicide in the past. The representativeness of homeless people in Japan who have psychiatric disorders in this study is limited but that the finding of 62.5% of homeless people suffering from some symptoms and a high

  13. Saksa asjalikkus ja kord 51. Mannheimi filmifesstivalil / Mart Kivastik

    Index Scriptorium Estoniae

    Kivastik, Mart, 1963-

    2002-01-01

    Mannheimi-Heidelbergi 51. filmifestival Saksamaal. Lähemalt kolmest mängufilmist rootslaste "Tokyo müra" ("Tokyo Noise") : režissöörid Kristian Petri, Jan Röed ja Johan Söderberg, ameeriklaste "Sitikas" ("Bug") : režissöör Matt Manfred ning hiinlaste "Kodutee" ("Wo de fu qin mu qin") : režissöör Zhang Yimou

  14. Características clínicas y epidemiológicas de la catarata congénita e infantil Clinical and epidemiological characteristics of the congenital and infantile cataract

    Directory of Open Access Journals (Sweden)

    Merixy Charón Milián

    2012-12-01

    Full Text Available Introducción: la catarata de cualquier etiología es la una de las causas más importantes de ceguera tratable en los niños. Objetivos: caracterizar, desde los puntos de vista clínico y epidemiológico, la catarata congénita e infantil. Métodos: se realizó un estudio observacional, descriptivo y retrospectivo en el Hospital Pediátrico "William Soler", entre enero de 2004 y junio de 2006. Se analizaron las variables: edad, sexo, procedencia, vía de captación, síntomas, factores de riesgo, localización, etiología probable y lateralidad de la catarata, alteraciones oculares asociadas y visión posquirúrgica. Los resultados se expresaron en media y porcentaje. Resultados: la edad promedio fue de 4,9 años y para menores de 1 año de 6,6 meses. Predominaron los varones (60,32 %, los pacientes de La Habana (25,4 %, la remisión médica como vía de captación (71,43 %, la leucocoria (30,15 %, la presencia de anomalías congénitas múltiples (34,92 %, la localización central de la catarata (44,44 %, la causa idiopática (41,27 % y la bilateralidad (66,67 %. El 34,92 % de los pacientes tenía asociada otra anomalía ocular, y el 59,04 % de los ojos operados alcanzaron visión entre 0,7 y 1,0. Conclusiones: en la serie analizada predominaron los lactantes menores de 2 meses y los varones, los pacientes de La Habana, la remisión médica, la leucocoria y las anomalías congénitas múltiples asociadas, la localización central y la posible etiología; en las bilaterales, el origen hereditario; y en las unilaterales, la causa desconocida. La mejoría visual posquirúrgica fue mayor a medida que disminuyó la edad del paciente al momento de realizar la cirugía.Introduction: cataract of any etiology is one of the most important causes of treatable blindness in children. Objectives: to clinically and epidemiologically characterize the congenital and infantile cataract. Methods: a retrospective, observational and descriptive study was carried

  15. Niveles de inmunoglobulinas IgA e IgM en recién nacidos y correlación con infección congénita

    Directory of Open Access Journals (Sweden)

    Rafael Ferrer Montoya

    1998-03-01

    Full Text Available Se realizó un estudio analítico y prospectivo en 600 recién nacidos, de los niveles sanguíneos de IgM e IgA y su relación con el riesgo de infección congénita. Se encontró elevada la IgM en 10 neonatos (1,7 % y la IgA en 18 (3 %. Se halló una buena correlación (OR y significancia estadística de IgM e IgA elevadas en los neonatos cuyas madres tuvieron líquido amniótico caliente y/o fétido, ruptura de las membranas de más de 24 horas y fiebre intraparto. También hubo una buena correlación (OR y significancia estadística de las Igs elevadas en neonatos con bronconeumonía y sepsis generalizada congénita. De los cultivos bacteriológicos existió una buena correlación (OR y significancia estadística en el hemocultivo y exudado faríngeo y las Igs elevadas y el residuo gástrico con la IgM elevada. Las bacterias grampositivas y gramnegativas aisladas en los neonatos tuvieron buena correlación (OR y significancia estadística, excepto para la IgA en las bacterias gramnegativas. Los 4 neonatos fallecidos por infección congénita tuvieron IgM elevadas.A prospective analytical study of IgM and IgA inmunoglobulin levels of 600 neonates and their correlation with congenital infection risks was made. 10 neonates (1.7 % presented a high IgM level whereas 18 (3 % had a raised IgA level. A good correlation (OR and statistical significance of raised IgA and IgM levels were found in newborns of mothers who had had hot and/or fetid amniotic fluid; ruptured membranes for over 24 hours and intralabor fever. Good correlation and statistical significance of high Igs were also present in neonates affected by bronchopneumonia and general congenital sepsis. As to the bacteriological cultures, good correlation and statistical significance was found in hemoculture and pharyngeal exudate, as well as raised Igs levels, and gastric residues with high IgM level. Gram-positive and gram-negative bacteria isolated from newborns presented good correlation

  16. Child deaths from injury in the special wards of Tokyo, Japan (2006-2010): a descriptive study.

    Science.gov (United States)

    Suzuki, Hideto; Hikiji, Wakako; Tanifuji, Takanobu; Abe, Nobuyuki; Fukunaga, Tatsushige

    2014-01-01

    There has been increasing interest in the formal review of child deaths in Japan. In this study we examined the causes and scene information regarding child deaths from injury in Tokyo, the capital of Japan, as preparation for implementation of a full-scale review of child deaths. Documents on deaths from injury (excluding homicides) investigated by the Tokyo Medical Examiner's Office during the period from 2006 through 2010 were reviewed. Deaths of children younger than 18 years (N = 217) were selected as the study sample. We examined the cause of and information on the death and were particularly interested in whether a case had preventable factors. Overall, 67% of the cases were deaths from unintentional injury. The main cause of death among children younger than 1 year was asphyxia, and the proportions of deaths from traffic accidents were higher in older age groups. Thirty percent of deaths from injury were due to suicide, and all cases of suicide were among children older than 10 years. Although analysis of preventable factors was difficult in some cases, owing to limited information on the death scene, 87% of deaths from unintentional injury, excluding those involving traffic accidents, had preventable factors. Most unintentional child deaths from injury appear to be preventable. Development of a system to collect detailed information on the scene at the time of death will help decrease child deaths in Japan.

  17. Risk factors for conversion of laparoscopic cholecystectomy to open surgery associated with the severity characteristics according to the Tokyo guidelines.

    Science.gov (United States)

    Asai, Koji; Watanabe, Manabu; Kusachi, Shinya; Matsukiyo, Hiroshi; Saito, Tomoaki; Kodama, Hajime; Kiribayashi, Takaharu; Enomoto, Toshiyuki; Nakamura, Yoichi; Okamoto, Yasushi; Saida, Yoshihisa; Nagao, Jiro

    2014-12-01

    The aim of this retrospective study was to identify the risk factors associated with the severity characteristics in the Tokyo guidelines for conversion to open surgery in patients with acute cholecystitis (AC) who underwent laparoscopic cholecystectomy. A total of 225 patients were enrolled in the study. The patients were classified into two groups: a conversion group and a no-conversion group. The preoperative characteristics and therapeutic strategy were analyzed as risk factors for conversion to open surgery. The postoperative outcomes were also analyzed. Conversion to open surgery occurred in 29 patients (12.9%), including seven patients (6.7%) with mild AC and 22 patients (18.5%) with moderate AC. A univariate analysis showed that the risk factors for conversion to open surgery included a duration of symptoms longer than 72 h, an elevated C-reactive protein (CRP) value and the Tokyo guidelines 2013 (TG 13) severity classification. The multivariate analysis showed that the risk factors for conversion to open surgery included a duration of symptoms longer than 72 h and a CRP value >11.5 mg/dl. A duration of symptoms longer than 72 h, which is included in the criterion for moderate AC severity in the TG 13, was an independent risk factor for conversion to open surgery. In addition, adoption of a high CRP value as an additional criterion for moderate AC may increase the utility of the TG 13.

  18. Accidental ingestion or aspiration of foreign objects at Tokyo Dental College Chiba Hospital over last 4 years.

    Science.gov (United States)

    Hisanaga, Ryuichi; Takahashi, Toshiyuki; Sato, Toru; Yajima, Yasutomo; Morinaga, Kazuki; Ohata, Hitoshi; Hirata, SoIchiro; Mamiya, Hideki; Kinumatsu, Takashi; Yakushiji, Takashi; Hagita, Keiko

    2014-01-01

    The aim of this study was to investigate cases of accidental ingestion or aspiration occurring at Tokyo Dental College Chiba Hospital over the last 4 years in order to determine how the incidence of such events could be reduced. Forty cases of accidents occurring at our hospital over a 4-year period commencing in 2008 (representing 27% of the total number of accidents) included accidental ingestion in 39 patients and aspiration in one. Most of these accidents occurred during the removal or placement of restorations or prosthetics, and the ingested objects were mostly crowns and inlays. Accidental ingestion or aspiration occurred more frequently in the right molar region and when procedures were conducted by practitioners with less than 1 to 7 years of experience, and especially 1 to 3 years only. A higher rate of such accidents was observed in male patients in their 50s to 70s. The conventional safety procedures developed by the Medical Risk Management Team should be adhered to wherever possible. Furthermore, we propose the following measures based on the present results: accident prevention training for students and clinical trainees; improvement of the in-hospital manual; personal coaching for those breaching the guidelines of the safety manual; and raising awareness of the need for greater care in preventing incidents of accidental ingestion or aspiration at the Tokyo Dental College Chiba Hospital.

  19. Child Deaths From Injury in the Special Wards of Tokyo, Japan (2006–2010): A Descriptive Study

    Science.gov (United States)

    Suzuki, Hideto; Hikiji, Wakako; Tanifuji, Takanobu; Abe, Nobuyuki; Fukunaga, Tatsushige

    2014-01-01

    Background There has been increasing interest in the formal review of child deaths in Japan. In this study we examined the causes and scene information regarding child deaths from injury in Tokyo, the capital of Japan, as preparation for implementation of a full-scale review of child deaths. Methods Documents on deaths from injury (excluding homicides) investigated by the Tokyo Medical Examiner’s Office during the period from 2006 through 2010 were reviewed. Deaths of children younger than 18 years (N = 217) were selected as the study sample. We examined the cause of and information on the death and were particularly interested in whether a case had preventable factors. Results Overall, 67% of the cases were deaths from unintentional injury. The main cause of death among children younger than 1 year was asphyxia, and the proportions of deaths from traffic accidents were higher in older age groups. Thirty percent of deaths from injury were due to suicide, and all cases of suicide were among children older than 10 years. Although analysis of preventable factors was difficult in some cases, owing to limited information on the death scene, 87% of deaths from unintentional injury, excluding those involving traffic accidents, had preventable factors. Conclusions Most unintentional child deaths from injury appear to be preventable. Development of a system to collect detailed information on the scene at the time of death will help decrease child deaths in Japan. PMID:24705644

  20. [Civil engineering education at the Imperial College of Engineering in Tokyo: an analysis based on Ayahiko Ishibashi's memoirs].

    Science.gov (United States)

    Wada, Masanori

    2014-01-01

    The Imperial College of Engineering (ICE or Kobu-Daigakko) in Tokyo, founded in 1873 under the auspices of the Ministry of Public Works, was one of the most prominent modern institutions of engineering education in early Meiji Japan. Previous studies have revealed that the ICE offered large scale practical training programs at enterprises of the Ministry, which sometimes lasted several months, and praised their ideal combination of theory and practice. In reality, it has been difficult to evaluate the quality of education at the ICE mainly because of scarcity of sources. ICE students published a collection of memoirs for alumni members, commemorating the fiftieth-year of the history of the Tokyo Imperial University. Drawing on the previously neglected collection of students' memoires, this paper appraises the education of civil engineering offered by the ICE. The paper also compares this collection with other official records of the college, and confirms it as a reliable source, even though it contains some minor errors. The author particularly uses the memoirs by Ayahiko Ishibashi, one of the first graduates from its civil engineering course, who left sufficient reminiscences on education that he received. This paper, as a result, illustrates that the main practical training for the students of civil engineering was limited to designing process, including surveying. Furthermore, practical training that Ishibashi received at those enterprises often lacked a plan, and its effectiveness was questionable.

  1. Prehospital management of sarin nerve gas terrorism in urban settings: 10 years of progress after the Tokyo subway sarin attack.

    Science.gov (United States)

    Tokuda, Yasuharu; Kikuchi, Makiko; Takahashi, Osamu; Stein, Gerald H

    2006-02-01

    Chemical agents have been used previously in wartime on numerous occasions, from World War I to the Gulf War. In 1994 and 1995, sarin nerve gas was used first in peacetime as a weapon of terrorism in Japan. The Tokyo subway sarin attack was the first large-scale disaster caused by nerve gas. A religious cult released sarin gas into subway commuter trains during morning rush hour. Twelve passengers died and about 5500 people were harmed. Sarin is a highly toxic nerve agent that can be fatal within minutes to hours. It causes the clinical syndrome of cholinergic hyperstimulation by inhibition of the crucial enzyme acetylcholinesterase. Therapy of nerve agent toxicity is divided into three categories, decontamination, respiratory support, and antidotes. All of these therapies may be given simultaneously. This article reviews toxicology and management of this acute chemical emergency. To help minimize the possible catastrophic impact on the public, we make several recommendations based on analysis of the Tokyo subway sarin attack and systematically review the current scientific literature.

  2. Spatiotemporal distribution and fluctuation of radiocesium in Tokyo Bay in the five years following the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident.

    Science.gov (United States)

    Yamazaki, Hideo; Ishida, Masanobu; Hinokio, Ryoichi; Yamashiki, Yosuke Alexandre; Azuma, Ryokei

    2018-01-01

    A monitoring survey was conducted from August 2011 to July 2016 of the spatiotemporal distribution in the 400 km2 area of the northern part of Tokyo Bay and in rivers flowing into it of radiocesium released from the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident. The average inventory in the river mouth (10 km2) was 131 kBq⋅m-2 and 0.73 kBq⋅m-2 in the central bay (330 km2) as the decay corrected value on March 16, 2011. Most of the radiocesium that flowed into Tokyo Bay originated in the northeastern section of the Tokyo metropolitan area, where the highest precipitation zone of 137Cs in soil was almost the same level as that in Fukushima City, then flowed into and was deposited in the Old-Edogawa River estuary, deep in Tokyo Bay. The highest precipitation of radiocesium measured in the high contaminated zone was 460 kBq⋅m-2. The inventory in sediment off the estuary of Old-Edogawa was 20.1 kBq⋅m-2 in August 2011 immediately after the accident, but it increased to 104 kBq⋅m-2 in July 2016. However, the radiocesium diffused minimally in sediments in the central area of Tokyo Bay in the five years following the FDNPP accident. The flux of radiocesium off the estuary decreased slightly immediately after the accident and conformed almost exactly to the values predicted based on its radioactive decay. Contrarily, the inventory of radiocesium in the sediment has increased. It was estimated that of the 8.33 TBq precipitated from the atmosphere in the catchment regions of the rivers Edogawa and Old-Edogawa, 1.31 TBq migrated through rivers and was deposited in the sediments of the Old-Edogawa estuary by July 2016. Currently, 0.25 TBq⋅yr-1 of radiocesium continues to flow into the deep parts of Tokyo Bay.

  3. Comparison of plasma levels of nutrient-related biomarkers among Japanese populations in Tokyo, Japan, São Paulo, Brazil, and Hawaii, USA.

    Science.gov (United States)

    Iwasaki, Motoki; Franke, Adrian A; Hamada, Gerson S; Miyajima, Nelson T; Sharma, Sangita; Ishihara, Junko; Takachi, Ribeka; Tsugane, Shoichiro; Le Marchand, Loïc

    2015-03-01

    Previous studies of Japanese migrants have suggested that the increase in colorectal cancer rates occurring after migration is slower among Japanese Brazilians than among Japanese Americans. We hypothesized that this difference may partly reflect differences in vegetable and fruit intake between the populations. Using data from validation studies of food frequency questionnaires being used in comparative case-control studies of colorectal adenoma in Tokyo, São Paulo, and Hawaii, plasma carotenoid, retinol, tocopherol, and coenzyme Q10 levels were measured by high-performance liquid chromatography, and 25-hydroxy vitamin D levels were estimated by enzyme-linked immunosorbent assay. Plasma levels were compared by analysis of covariance between 142 Japanese in Tokyo, 79 Japanese Brazilians in São Paulo, and 78 Japanese Americans in Hawaii. Overall, we found significantly lower plasma carotenoid levels, except for lycopene levels, and retinol levels in Japanese Americans compared with Japanese in Tokyo and Japanese Brazilians. The plasma total carotenoid level was highest in Japanese Brazilians. Compared with the mean level among Japanese Brazilians (1741.2 ng/ml), P for difference was 0.03 among Japanese in Tokyo (1514.4 ng/ml) and less than 0.01 for Japanese Americans (1257.7 ng/ml). Plasma lycopene and tocopherol levels did not substantially differ between the three populations. We also found significantly lower plasma levels of 25-hydroxy vitamin D and total coenzyme Q10 in Japanese in Tokyo than in Japanese Americans and Japanese Brazilians. Higher levels of plasma carotenoids among Japanese Brazilians than among Japanese in Tokyo and Hawaii may have contributed to the slower pace of the increase in colorectal cancer rates observed in that population after migration.

  4. Spatiotemporal distribution and fluctuation of radiocesium in Tokyo Bay in the five years following the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident

    Science.gov (United States)

    Yamazaki, Hideo; Hinokio, Ryoichi; Yamashiki, Yosuke Alexandre; Azuma, Ryokei

    2018-01-01

    A monitoring survey was conducted from August 2011 to July 2016 of the spatiotemporal distribution in the 400 km2 area of the northern part of Tokyo Bay and in rivers flowing into it of radiocesium released from the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident. The average inventory in the river mouth (10 km2) was 131 kBq⋅m-2 and 0.73 kBq⋅m-2 in the central bay (330 km2) as the decay corrected value on March 16, 2011. Most of the radiocesium that flowed into Tokyo Bay originated in the northeastern section of the Tokyo metropolitan area, where the highest precipitation zone of 137Cs in soil was almost the same level as that in Fukushima City, then flowed into and was deposited in the Old-Edogawa River estuary, deep in Tokyo Bay. The highest precipitation of radiocesium measured in the high contaminated zone was 460 kBq⋅m-2. The inventory in sediment off the estuary of Old-Edogawa was 20.1 kBq⋅m-2 in August 2011 immediately after the accident, but it increased to 104 kBq⋅m-2 in July 2016. However, the radiocesium diffused minimally in sediments in the central area of Tokyo Bay in the five years following the FDNPP accident. The flux of radiocesium off the estuary decreased slightly immediately after the accident and conformed almost exactly to the values predicted based on its radioactive decay. Contrarily, the inventory of radiocesium in the sediment has increased. It was estimated that of the 8.33 TBq precipitated from the atmosphere in the catchment regions of the rivers Edogawa and Old-Edogawa, 1.31 TBq migrated through rivers and was deposited in the sediments of the Old-Edogawa estuary by July 2016. Currently, 0.25 TBq⋅yr-1 of radiocesium continues to flow into the deep parts of Tokyo Bay. PMID:29494667

  5. Geographically explicit urban land use change scenarios for Mega cities: a case study in Tokyo

    Science.gov (United States)

    Yamagata, Y.; Bagan, H.; Seya, H.; Nakamichi, K.

    2010-12-01

    In preparation for the IPCC 5th assessment report, the international modeling community is developing four Representative Concentration Paths employing the scenarios developed by four different Integrated Assessment Models. These RCPs will be employed as an input to climate models, such as Earth System Models. In these days, the importance of assessment of not only global but also local (city/zone level) impacts of global change has gradually been recognized, thereby downscaling climate models are one of the urgent problems to be solved. Needless to say, reliable downscaling requires spatially high resolution land use change scenarios. So far, there has been proposed a lot of methods for constructing land use change scenarios with considering economic behavior of human, such as agent-based model (e.g., Parker et al., 2001), and land use transport (LUT) model (e.g., Anas and Liu, 2007). The latter approach in particular has widely been applied to actual urban/transport policy; hence modeling the interaction between them is very important for creating reliable land use change scenarios. However, the LUT models are usually built based on the zones of cities/municipalities whose spatial resolutions are too low to derive sensible parameters of the climate models. Moreover, almost all of the works which attempt to build spatially high resolution LUT model employs very small regions as the study area. The objective of this research is deriving various input parameters to climate models such as population density, fractional green vegetation cover, and anthropogenic heat emission with spatially high resolution land use change scenarios constructed with LUT model. The study area of this research is Tokyo metropolitan area, which is the largest urban area in the world (United Nations., 2010). Firstly, this study employs very high ground resolution zones composed of micro districts around 1km2. Secondly, the research attempt to combine remote sensing techniques and LUT models

  6. Evaluation of non-methane hydrocarbon (NMHC) emissions based on an ambient air measurement in Tokyo area, Japan

    Science.gov (United States)

    Matsunaga, Sou N.; Chatani, Satoru; Morikawa, Tazuko; Nakatsuka, Seiji; Suthawaree, Jeeranut; Tajima, Yosuke; Kato, Shungo; Kajii, Yoshizumi; Minoura, Hiroaki

    2010-12-01

    Non-methane hydrocarbons (NMHCs) are known to have an important role on air quality due to their high reactivity. NMHC analysis has been performed on 148 ambient air samples collected at five different sites in the Kanto area (Tokyo metropolitan area and surrounding six prefectures) of Japan in summer and winter of 2008, and fifty NMHCs have been determined and quantified. A field measurement campaign has been conducted at one of the busiest intersections in Tokyo metropolitan area in winter of 2008. NMHC emissions are evaluated through comparison of distributions of individual NMHCs emitted from motor vehicles, which are estimated from the measurements, with those determined from the current emissions inventory. The comparison revealed that the measured distributions of acetylene, ethylene and toluene showed a good agreement with those estimated from the emissions inventory (the values estimated from the measurements are a factor of 1.5, 0.56 and 2.3 larger than the emissions inventory in median, respectively), however, propane and isobutane are found to be significantly underestimated in the emissions inventory (the measured values were a factor of 18 and 5.1 larger than the emissions inventory, respectively). The significant underestimate of propane can be explained by that the current emissions inventory does not consider emissions from liquefied propane gas (LPG) fueled vehicles. However, for isobutane, reasons for the underestimate are still unclear. Another field measurement has been conducted in summer of 2008, where the air samples have been collected at three different sites on the ground and by a helicopter as well. Remarkable high concentrations of 1-butene and cis- and trans-2-butenes have been sporadically observed in the samples collected at Urayasu in the coastal area of Tokyo bay. Calculated propylene equivalent (PE) concentrations of butenes revealed that those have a significantly important role in ozone formation when the air plume is affected

  7. The Effectiveness of Service Learning Practice for Teacher Education in Japan: For the Support of a New Subject Called, "Houshi," for a High School in Tokyo

    Science.gov (United States)

    Miyazaki, Takeshi

    2012-01-01

    This study presented practices based on Service Learning that gave pre-service teachers ideas about the significance of Service Learning and the challenges that exist. They made lesson plans for "Houshi" (=Service) and conducted them in a high school in Tokyo's public school system. Service Learning is one of the effective methods in…

  8. Outcomes of early cholecystectomy (within 7 days of admission) for acute cholecystitis according to diagnosis and severity grading by Tokyo 2013 Guideline

    Science.gov (United States)

    Sert, İsmail; İpekci, Fuat; Engin, Ömer; Karaoğlan, Muharrem; Çetindağ, Özhan

    2017-01-01

    Objective The timing of early cholecystectomy in acute cholecystitis is still controversial, and data regarding the use of Tokyo 2013 guideline for diagnosis and severity grading in Acute Cholecystitis is limited. The aim of this study was to evaluate the clinical and pathologic outcomes of early cholecystectomy after 72 hr and within seven days of index admission according to Tokyo 2013 guideline for diagnosis and severity grading of Acute cholecystitis (in patients with Acute cholecystitis. Material and Methods Medical charts of 172 patients who underwent early cholecystectomy after 72 hr and within 7 days of index admission with a diagnosis of Acute cholecystitis between Aug 2009 and Apr 2014 were retrospectively analyzed. Patients were classified according Tokyo 2013 guideline criteria. Results The median age of the study group was 52 yr. The rates of open and laparoscopic cholecystectomies was 53.5% and 33.1%, respectively. Conversion to open cholecystectomy was performed in 19 patients (13.4 %). The median length of hospital stay was 7 days. Eighty-four patients (59.2%) met the criteria for a definite diagnosis of Acute cholecystitis according to Tokyo 2013 guideline. Longer postoperative and total length of hospital stay was determined in patients with a definite diagnosis. Conclusion Increased severity grading is correlated with longer pre- and post-operative hospital stay. Early cholecystectomy in Acute cholecystitis performed by experienced surgeons after 72 hr of admission and within 7 days maybe a feasible and safe procedure. PMID:28740955

  9. Comparison of Toxoplasma gondii Seroprevalence in Shelter Cats and Dogs during 1999-2001 and 2009-2011 in Tokyo, Japan.

    Science.gov (United States)

    Oi, Masaaki; Yoshikawa, Souichi; Maruyama, Soichi; Nogami, Sadao

    2015-01-01

    Toxoplasma gondii is an important human health concern with respect to abortion, congenital hydrocephalus, and encephalitis in immunocompromised people. Cats and dogs both are potential sources of T. gondii because they have close contact with humans. However, no epidemiological surveys have been conducted in Tokyo over the past decade. Therefore, the present study investigated and compared the seroprevalence of T. gondii infection in shelter cats and dogs during 1999-2001 and 2009-2011 in Tokyo, Japan. Serum samples were collected from 337 shelter cats and 325 shelter dogs in urban and suburban areas of Tokyo, during 1999-2001 (233 cats and 219 dogs) and 2009-2011 (104 cats and 106 dogs). T. gondii antibodies were measured in the serum samples using a commercial latex agglutination test. Data were compared using the Fisher's exact test, and significance was indicated at P cats was 5.6% (13 of 233) in 1999-2001 and 6.7% (7 of 104) in 2009-2011, and that in dogs was 1.8% (4 of 219) and 1.9% (2 of 106), respectively. Significantly higher seroprevalence was observed in cats from suburban areas compared with cats in urban areas during both periods (P cats and dogs in Tokyo is considerably low as the seroprevalence has reached a steady state.

  10. Disturbance of recruitment success of mantis shrimp in Tokyo Bay associated with effects of hypoxia on the early life history.

    Science.gov (United States)

    Kodama, Keita; Tajima, Yoshihiro; Shimizu, Takamichi; Ohata, Satoshi; Shiraishi, Hiroaki; Horiguchi, Toshihiro

    2014-08-30

    We investigated effects of severe hypoxia (dissolved oxygen Tokyo Bay. Ten-year field surveys were conducted to examine quantitative relationships in annual mean densities of larvae and juveniles, and spatial distribution of juveniles and severe hypoxia. There was no significant correlation between annual mean densities of larvae and juveniles, suggesting that mortality during larval or juvenile stages varies among years, which might have regulated abundance of young-of-the-year juveniles. Juvenile density was low in the severely hypoxic area, implying that hypoxia could affect survivals and spatial distribution of juveniles. Meanwhile, there are yearly fluctuations in juvenile density in normoxic areas of both northern and southern part of the bay. This evidence suggests that abundance of post-settled juveniles might have been determined by not only effects of hypoxia, but also other factors influencing mortality during the early life stages. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. La restauración de un edificio escolar de F.LL. Wright en Tokyo: Jiyu Gakuen Myonichikan

    Directory of Open Access Journals (Sweden)

    Junko Takano

    2004-12-01

    Full Text Available La recuperación de la Escuela de Wright en Tokyo supone una apuesta por la pervivencia del único edificio íntegro que se conserva de la estancia del arquitecto en la ciudad. Su rehabilitación, que ha contemplado la sustitución de gran parte de los entramados de listones de madera de paredes y techos, ha sido realizada con una atención exquisita a la configuración y mobiliario original del conjunto. El edificio restaurado ha abierto sus puertas al público en virtud de su reciente declaración como Bien de Interés Cultural.

  12. Growth inhibition of HeLa cell by internalization of Mycobacterium bovis Bacillus Calmette-Guérin (BCG Tokyo

    Directory of Open Access Journals (Sweden)

    Asahina Izumi

    2009-12-01

    Full Text Available Abstract Background Intravesical BCG immunotherapy is effective for preventing recurrence and progression in none muscle-invasive bladder cancer but the dosing schedule and duration of treatment remain empirical. The mechanisms by which intravesical BCG treatment mediates antitumor activity are currently poorly understood. Results HeLa cell infected with Mycobacterium bovis Bacillus Calmette-Guérin(BCG Tokyo which were different multiplicity of infection(MOI. Proliferation of HeLa cell reduced in a dose-dependent manner by live BCG. The cytoplasm of the HeLa cell showed variety lysosomal stages by internalized and interacted BCG. Conclusion Proliferated Live BCG secreted the protein and depressed the growth of tumor. The possibility for clinical introduction of BCG therapy for carcinoma reported with review of literature.

  13. Cherry blossom phenological data since the seventeenth century for Edo (Tokyo), Japan, and their application to estimation of March temperatures

    Science.gov (United States)

    Aono, Yasuyuki

    2015-04-01

    The changes in March mean temperatures in Edo (Tokyo), Japan, since the seventeenth century, were reconstructed using phenological data for the cherry blossoms of Prunus jamasakura deduced from old diaries and chronicles. The observations of the time of full blossoming and of cherry blossom viewing parties were acquired and used to construct a full-blossoming phenological data series for P. jamasakura. Phenological data from 207 of the years from 1601 to 1905 were used for this study. The reconstructed temperatures suggested the existence of two cold periods (the second half of the seventeenth century and the beginning of the nineteenth century), during which times the estimated March mean temperatures were about 4 °C and 5 °C, respectively. These two cold periods at Edo coincided with those reconstructed at Kyoto in previous studies. These cold periods coincided with two less extreme periods, the Maunder and Dalton minima, in the long-term solar variation cycle.

  14. Tokyo Tech–Hitotsubashi Interdisciplinary Conference : New Approaches to the Analysis of Large-Scale Business and Economic Data

    CERN Document Server

    Takayasu, Misako; Takayasu, Hideki; Econophysics Approaches to Large-Scale Business Data and Financial Crisis

    2010-01-01

    The new science of econophysics has arisen out of the information age. As large-scale economic data are being increasingly generated by industries and enterprises worldwide, researchers from fields such as physics, mathematics, and information sciences are becoming involved. The vast number of transactions taking place, both in the financial markets and in the retail sector, is usually studied by economists and management and now by econophysicists. Using cutting-edge tools of computational analysis while searching for regularities and “laws” such as those found in the natural sciences, econophysicists have come up with intriguing results. The ultimate aim is to establish fundamental data collection and analysis techniques that embrace the expertise of a variety of academic disciplines. This book comprises selected papers from the international conference on novel analytical approaches to economic data held in Tokyo in March 2009. The papers include detailed reports on the market behavior during the finan...

  15. Measurement of 26Al in Antarctic ice with the MALT-AMS system at the University of Tokyo

    Science.gov (United States)

    Horiuchi, Kazuho; Matsuzaki, Hiroyuki; Ohta, Aoi; Shibata, Yasuyuki; Motoyama, Hideaki

    2007-06-01

    We have attempted to determine the 26Al concentration of Antarctic ice sampled from the vicinity of the Dome Fuji Research Station using accelerator mass spectrometry (AMS) at MALT (MicroAnalysis Laboratory, Tandem accelerator) of the University of Tokyo. Because the expected concentration of 26Al in ice is very low, our standard procedure for the AMS measurement was re-examined and refined. The observed 26Al concentration ranged between 160 and 210 atoms g-1. The averaged value of the 26Al/10Be ratio from two samples was 1.75 ± 0.19 × 10-3, which agrees well with recently reported values for the meteoric 26Al/10Be ratio from Antarctic ice and air filter residues. This result implies the possibility of future 26Al/10Be dating of old Antarctic ice.

  16. Lecture notes of the technical training curriculum of the Institute of Nuclear Study, University of Tokyo, 1990

    International Nuclear Information System (INIS)

    1993-06-01

    This report is a transcript of lectures for the technical staff, held in the Institute of Nuclear Study, University of Tokyo, from November 1990 to April 1992. Following themes are included in this report. (1) Cyclotron technology, (2) measuring technology of the peripheral devices for cyclotron, (3) heavy ion cyclotron technology, (4) beam cooling technology, (5) proton linac technology, (6) heavy ion linac technology, (7) measuring technology of electron and its equipments, (8) the latest high energy large experimental device and its measurement (HERA, ZENS experiment), (9) superconducting kaon spectrometer (SKS) and large superconducting magnet, (10) present status of the precision technology for accelerators, (11) the computer as basic technology of elementary particle and nuclear experiments, (12) present status of radiation management and measurement technology, (13) handling and processing method of the hazardous materials, (14) analog technology of the equipments for accelerators, and the summary of NIRS-Heavy Ion Medical Accelerator in Chiba (HIMAC). (T.F.)

  17. The Japanese mind in disaster 3.11. Web survey in Tohoku, Tokyo, Osaka, and Kyushu (1)

    International Nuclear Information System (INIS)

    Tsuchida, Shoji; Tsujikawa, Norifumi; Shiotani, Takamasa; Nakagawa, Yuri

    2011-01-01

    The Tohoku Disaster 3.11 with earthquake M9.0, tsunami, and the Fukushima accident brought the inhabitants horrible damages. Tohoku area people [N=1,000], Tokyo people [N=500], Osaka people [N=500], and Kyushu people [N=500] (Total N=2,500) were targeted at Online survey which was designed to figure out the people's responses to the disaster and their psychological factors. The results showed that the Tohoku area people were in relatively solid local communities and bonded intimately each other. They thought it proper to cope with the disaster through community. They had more negative attitudes to Nuclear Power, and their trust toward the TEPCO and the government was more negative in dealing with the Fukushima accident. (author)

  18. Report of the research results with University of Tokyo, Nuclear Engineering Research Laboratory's Facilities in fiscal 1991

    International Nuclear Information System (INIS)

    1992-01-01

    This publication summarizes the results of the joint utilization of the nuclear reactor 'Yayoi' and the electron beam accelerator in the Nuclear Engineering Research Laboratory, University of Tokyo, in fiscal year 1991. The Yayoi was operated smoothly throughout the year, and the number of research themes, for which the reactor Yayoi was jointly utilized, and the related themes reached 21 cases. After the linear accelerator was reconstructed as the twin linac, the joint utilization was resumed in October, 1989, and the number of research themes, was 15 cases. In this publication, in addition to the utilization reports, also the reports of 15 cases of Yayoi Study Meetings held in fiscal year 1991 are collected. (K.I.)

  19. Design of enclosure and support facilities for the University of Tokyo Atacama Observatory 6.5-m Telescope

    Science.gov (United States)

    Sako, S.; Yoshii, Y.; Doi, M.; Kohno, K.; Miyata, T.; Motohara, K.; Kawara, K.; Tanaka, M.; Minezaki, Takeo; Morokuma, T.; Tamura, Y.; Tanabe, T.; Takahashi, H.; Konishi, M.; Kamizuka, Takafumi; Koshida, S.; Kato, Natsuko; Aoki, T.; Soyano, T.; Tarusawa, K.; Handa, T.; Bronfman, L.; Ruiz, M. T.; Hamuy, M.; Mendez, R.

    2014-07-01

    A basic design of enclosure and support facilities for the University of Tokyo Atacama observatory (TAO) 6.5-m telescope is described in this paper. The enclosure facility has a carousel shape with an open-space near the ground surface. The upper carousel rotates independently of the telescope. Horizontally opened slit doors, a dozen ventilation windows, wind and moon shields, and an overhead bridge-crane are equipped. For safety reasons, most of maintenance walkways are placed inside of the enclosure facility. An observation floor of the enclosure facility is connected to the support facility via a bridge for maintenance of observation instruments and a primary mirror of the telescope. Air inside of the enclosure and support facilities is exhausted to an underground tunnel.

  20. Associations of acute exposure to fine and coarse particulate matter and mortality among older people in Tokyo, Japan.

    Science.gov (United States)

    Yorifuji, Takashi; Kashima, Saori; Doi, Hiroyuki

    2016-01-15

    Recent studies have reported adverse health effects of short-term exposure to coarse particles independent of particulate matter less than 2.5 μm in diameter (PM2.5), but evidence in Asian countries is limited. We therefore evaluated associations between short-term exposure to particulate matter (PM) and mortality among older people in Tokyo, Japan. We used a time-stratified, case-crossover design. Study participants included 664,509 older people (≥65 years old) in the 23 urbanized wards of the Tokyo Metropolitan Government, who died between January 2002 and December 2013. We obtained PM2.5 and suspended particulate matter (SPM; PM<7 μm in diameter) from one general monitoring station. We calculated PM7-2.5 by subtracting PM2.5 from SPM to account for coarse particles. We then used conditional logistic regression to estimate odds ratios (ORs) and 95 confidence intervals (CIs). Same-day PM2.5 and PM7-2.5 were independently associated with all-cause and cause-specific mortality related to cardiovascular and respiratory diseases; for example, both pollutants were positively associated with increased risk of all-cause mortality even after simultaneous adjustment for each pollutant: OR of 1.006 (95% CI: 1.003, 1.009) for PM2.5 and 1.016 (95% CI: 1.011, 1.022) for PM7-2.5. Even below concentrations stipulated by the Japanese air quality guidelines for PM2.5 and SPM (PM7), we observed adverse health effects. This study provides further evidence that acute exposure to PM2.5 and coarse particles is associated with increased risk of mortality among older people. Rigorous evaluation of air quality guidelines for daily average PM2.5 and larger particles should be continued. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Prevalence of caries in deciduous teeth in early modern Japan: analyses of human skeletons from Hitotsubashi (Tokyo, Japan).

    Science.gov (United States)

    Nagaoka, Tomohito

    2017-06-01

    The early modern Edo period in Japan refers to the division of chronological age dated from the seventeenth to nineteenth centuries. During that period, the social structure was stratified, with warriors at the top, followed by farmers, and finally townsmen at the bottom. I aimed to examine carious lesions in deciduous teeth in the commoners from the city of Edo (now Tokyo), to compare them with those in the warriors and commoners from Kyushu, and to reveal differences in the incidence of caries across social classes and regions. I examined 843 deciduous teeth of 115 individuals from the Hitotsubashi site in Tokyo. The comparative samples were obtained from warriors and commoners whose remains were excavated from the Sougenji and Kyoumachi sites, respectively, in Kyushu [Oyamada et al. (2008) Anthropol Sci 116:9-15]. The caries frequency in the Hitotsubashi sample was 11.3 %. Carious lesions in the upper teeth were more frequent than those in the lower teeth in all age groups. The upper incisors exhibited the highest frequency of caries, while there was almost no caries in the lower incisors and canines. I also found population differences in deciduous caries among the Edo populations. Remains of teeth excavated from Hitotsubashi were found to have a mild degree of caries compared to remains of teeth excavated from Sougenji and Kyoumachi in Kyushu in terms of caries frequency and location. Thus, the influence of regional differences in diet and living circumstances was stronger than expected, and the variation observed in the frequency of deciduous caries among the Edo populations cannot be explained by social class alone.

  2. Cultural differences in clinical leadership: a qualitative study comparing the attitudes of general dental practitioners from Greater Manchester and Tokyo.

    Science.gov (United States)

    Brocklehurst, P; Nomura, M; Ozaki, T; Ferguson, J; Matsuda, R

    2013-11-01

    Leadership has been argued to be a key component in the transformation of services in the United Kingdom and in Japan. In the UK, local professional networks have developed to provide clinician led care in dentistry; working to develop local plans to deliver improvements in the quality of care for patients. In Japan, the remuneration model for dental care has been revised with the aim to improve the service and tackle the current challenges of population health there. The aim of this study was to use semi-structured interviews and thematic analysis to explore general dental practitioners' (GDPs) understanding of the term 'leadership' and determine whether its meaning is culturally bound. Twelve participants were sampled purposively by the research team; identifying GDPs involved in leadership roles from across Greater Manchester and Tokyo. A set of open-ended questions was developed for semi-structured interviews a priori and the interviews continued until saturation. Interviews were recorded, transcribed verbatim and codes were developed into a coding frame for thematic analysis. Representative quotations are provided in the results. Fourteen codes were identified according to the aims of the study and organised into five overarching themes. 'Leadership as the relationship' was more pronounced among Japanese GDPs, while 'leadership as the individual' was common in GDPs from Greater Manchester. Differences were also found in respect of education and training in leadership. Training was also considered to be important by the GDPs from Japan, while UK GDPs felt leaders were more likely to be influenced by innate qualities. The interdependence of leadership and entrepreneurship was raised by both sets of GDPs. The concept of leadership was considered to be important by GDPs from both Greater Manchester and Tokyo; leadership was seen as providing strategy and direction for a clinical team. However, cultural influences were evident in how this was conceptualised.

  3. Risk perception and risk attitudes in Tokyo: A report of the first administration of DOSPERT+M in Japan

    Directory of Open Access Journals (Sweden)

    Alan Schwartz

    2013-11-01

    Full Text Available Background: The Domain-Specific Risk Taking scale (DOSPERT has been used to measure risk perceptions and attitudes in several nations and cultures. Takahashi translated DOSPERT to Japanese but DOSPERT responses from Japan have never been reported. Butler et al. (2012 developed an additional medical risk domain subscale to be added to DOSPERT to form DOSPERT+M. Objective: To describe the translation of the medical risk domain subscale to Japanese and to characterize domain-specific risk attitudes in Tokyo. Methods: Members of a probability-weighted online panel representative of the Tokyo metro area were randomized to complete pairs of DOSPERT+M tasks (risk attitude, risk perception, benefit perception. We explored relationships among domains through correlational and factor analysis; we tested the hypothesis that the medical risk domain and DOSPERT's health/safety domains were uncorrelated. Participants: One hundred eighty panelists. Results: Six of the original DOSPERT items (two each in the ethics, health/safety, and financial domains are not useable in Japan according to the Japanese Marketing Research Association code because they ask about participation in illegal activities; we thus used abbreviated versions of those domains leaving out these items. The DOSPERT+M items generally did not cluster cleanly into the expected domains, although items within the same domain usually were intercorrelated. Participants demonstrated domain-specific conventional risk attitudes, although nearly half of those assessed were perceived-risk neutral in all domains. Unlike our recently reported findings in the U.S. population, DOSPERT+M medical domain scores were associated with health/safety domain scores, although they were often more strongly associated with scores in other domains, such as recreational activities. Conclusion: The DOSPERT (and DOSPERT+M instruments are problematic in Japan but Japanese citizens may also differ from those of other nations

  4. Impact of the 2001 Tohoku-oki earthquake to Tokyo Metropolitan area observed by the Metropolitan Seismic Observation network (MeSO-net)

    Science.gov (United States)

    Hirata, N.; Hayashi, H.; Nakagawa, S.; Sakai, S.; Honda, R.; Kasahara, K.; Obara, K.; Aketagawa, T.; Kimura, H.; Sato, H.; Okaya, D. A.

    2011-12-01

    The March 11, 2011 Tohoku-oki earthquake brought a great impact to the Tokyo metropolitan area in both seismological aspect and seismic risk management although Tokyo is located 340 km from the epicenter. The event generated very strong ground motion even in the metropolitan area and resulted severe requifaction in many places of Kanto district. National and local governments have started to discuss counter measurement for possible seismic risks in the area taking account for what they learned from the Tohoku-oki event which is much larger than ever experienced in Japan Risk mitigation strategy for the next greater earthquake caused by the Philippine Sea plate (PSP) subducting beneath the Tokyo metropolitan area is of major concern because it caused past mega-thrust earthquakes, such as the 1703 Genroku earthquake (M8.0) and the 1923 Kanto earthquake (M7.9). An M7 or greater (M7+) earthquake in this area at present has high potential to produce devastating loss of life and property with even greater global economic repercussions. The Central Disaster Management Council of Japan estimates that an M7+ earthquake will cause 11,000 fatalities and 112 trillion yen (about 1 trillion US$) economic loss. In order to mitigate disaster for greater Tokyo, the Special Project for Earthquake Disaster Mitigation in the Tokyo Metropolitan Area was launched in collaboration with scientists, engineers, and social-scientists in nationwide institutions. We will discuss the main results that are obtained in the respective fields which have been integrated to improve information on the strategy assessment for seismic risk mitigation in the Tokyo metropolitan area; the project has been much improved after the Tohoku event. In order to image seismic structure beneath the Metropolitan Tokyo area we have developed Metropolitan Seismic Observation network (MeSO-net; Hirata et al., 2009). We have installed 296 seismic stations every few km (Kasahara et al., 2011). We conducted seismic

  5. Mortalidad infantil por malformaciones congénitas y condición socioeconómica: el caso de la Argentina Infant mortality due to congenital malformations and socioeconomic status: the case of Argentina

    Directory of Open Access Journals (Sweden)

    Rubén A. Bronberg

    2012-06-01

    Full Text Available OBJETIVO: Relacionar la tasa de mortalidad infantil por malformaciones congénitas (TMIMC y el porcentaje de muertes por malformaciones congénitas (%MMC con las características sociodemográficas y económicas en la Argentina. MÉTODOS: La población estudiada de la Argentina reside en 511 departamentos de 23 provincias, agrupadas en cinco regiones geográficas (Noroeste, Noreste, Centro, Cuyo y Patagonía. Las variables analizadas fueron la TMLMC y el %MMC calculados a partir de los nacimientos y las defunciones del quinquenio 2002-2006. Además, se utilizaron 21 variables del Censo de Población y Vivienda del 2001 (Instituto Nacional de Estadística y Censos de Argentina para construir el Indicador Sociodemográfico y Económico (ISDE mediante el análisis de componentes principales. Se realizaron pruebas de comparación para valorar si aparecían diferencias significativas entre las distintas regiones y las correlaciones entre indicadores, y de estos con la latitud y longitud departamental. RESULTADOS: La TMIMC no presentó correlación significativa con el ISDE ni con las coor denadas geográficas. El %MMC y el ISDE presentaron una correlación positiva significativa (P OBJECTIVE: Compare the infant mortality rate due to congenital malformations ( IMRCM and the percentage of deaths due to congenital malformations (%DCM with sociodemographic and economic characteristics in Argentina. METHODS: The Argentine study population resided in 511 departments of 23 provinces, grouped into five geographic regions (Northwest, Northeast, Central, Cuyo, and Patagonia. The analyzed variables were the IMRCM and the %DCM calculated on the basis of births and deaths during 2002-2006 period. In addition, 21 variables were used from the 2001 Population and Housing Census (National Census and Statistics Institute of Argentina to construct the Sociodemographic and Economic Indicator (SDEI through the analysis of principal components. Comparison tests were

  6. Carcinoma bronquíolo-alveolar associado a malformação congénita das vias aéreas pulmonares em adolescente assintomático

    Directory of Open Access Journals (Sweden)

    Francisco Abecasis

    2008-03-01

    Full Text Available Resumo: A malformação congénita das vias aéreas pulmonares (CPAM é uma entidade rara com potencial de transformação maligna. Relata-se o caso de um rapaz de 14 anos, assintomático, referenciado à consulta após detecção de imagem nodular na base do pulmão direito num radiograma de tórax. A tomografia computorizada (TC mostrou, no pulmão direito, formação redonda de média densidade com centro cavitado. Após um ano de seguimento, mantinha-se assintomático, sendo a imagem radiológica sobreponível. Em conjunto com a equipa de cirurgia cardiotorácica foi decidido proceder a biópsia excisional. O exame histológico revelou um carcinoma bronquíolo-alveolar mucinoso associado a CPAM tipo 1. Perante este resultado, o doente foi submetido a lobectomia inferior direita. No exame histológico do restante lobo, não se identificou tumor ou malformação residuais. Mantém-se assintomático e sem complicações passados dois anos. Tanto quanto é do conhecimento dos autores, este é o primeiro caso desta rara associação em Portugal. Discute-se a abordagem de lesões quísticas em doentes assintomáticos.Rev Port Pneumol 2007; XIV (2: 285-290 Abstract: Congenital pulmonary airway malformation (CPAM is a rare entity with potential for malignant transformation. We describe the case of a fourteen-year-old boy evaluated for the presence of a nodular image on the right lung on the chest x-ray. Computerized Tomography (CT showed a round lesion of medium density with cavitation on the right lung. After one year of follow-up the patient was still asymptomatic and the image was similar. With the agreement of the cardiothoracic surgeons an excisional biopsy was performed. The histological examination revealed a mucinous bronchioloalveolar carcinoma associated with a type 1 CPAM. The patient was then submitted to right inferior lobectomy. After two years follow-up he is asymptomatic and free of complications. To the authors best knowledge this

  7. Carcinoma bronquíolo-alveolar associado a malformação congénita das vias aéreas pulmonares em adolescente assintomático

    Directory of Open Access Journals (Sweden)

    Francisco Abecasis

    2008-03-01

    Full Text Available Resumo: A malformação congénita das vias aéreas pulmonares (CPAM é uma entidade rara com potencial de transformação maligna. Relata-se o caso de um rapaz de 14 anos, assintomático, referenciado à consulta após detecção de imagem nodular na base do pulmão direito num radiograma de tórax. A tomografia computorizada (TC mostrou, no pulmão direito, formação redonda de média densidade com centro cavitado. Após um ano de seguimento, mantinha-se assintomático, sendo a imagem radiológica sobreponível. Em conjunto com a equipa de cirurgia cardiotorácica foi decidido proceder a biópsia excisional. O exame histológico revelou um carcinoma bronquíolo-alveolar mucinoso associado a CPAM tipo 1. Perante este resultado, o doente foi submetido a lobectomia inferior direita. No exame histológico do restante lobo, não se identificou tumor ou malformação residuais. Mantém-se assintomático e sem complicações passados dois anos. Tanto quanto é do conhecimento dos autores, este é o primeiro caso desta rara associação em Portugal. Discute-se a abordagem de lesões quísticas em doentes assintomáticos. Abstract: Congenital pulmonary airway malformation (CPAM is a rare entity with potential for malignant transformation. We describe the case of a fourteen-year-old boy evaluated for the presence of a nodular image on the right lung on the chest x-ray. Computerized Tomography (CT showed a round lesion of medium density with cavitation on the right lung. After one year of follow-up the patient was still asymptomatic and the image was similar. With the agreement of the cardiothoracic surgeons an excisional biopsy was performed. The histological examination revealed a mucinous bronchioloalveolar carcinoma associated with a type 1 CPAM. The patient was then submitted to right inferior lobectomy. After two years follow-up he is asymptomatic and free of complications. To the authors best knowledge this is the first case reported in Portugal

  8. Cirugía de pacientes con cardiopatía congénita en España en el período 2012-2016: registro de intervenciones de la Sociedad Española de Cirugía Torácica-Cardiovascular

    OpenAIRE

    Luz Polo López; Tomasa Centella Hernández; José López Menéndez; Jacobo Silva Guisasola

    2017-01-01

    Resumen: La Sociedad Española de Cirugía Torácica-Cardiovascular presenta los resultados de actividad en cirugía cardiovascular sobre pacientes con cardiopatía congénita correspondientes al período 2012-2016 basado en un registro voluntario y anónimo de los centros españoles. Este artículo es complementario al registro general del año 2016 y ambos se publican conjuntamente. Mostramos datos de los últimos 5 años, coincidiendo con la fecha en que realizamos la última modificación del registro, ...

  9. Análisis de las malformaciones congénitas detectadas por el programa alfafetoproteína-ultrasonido genético Analysis of the congenital malformations detected by the alpha-fetoprotein-genetic ultrasound program

    Directory of Open Access Journals (Sweden)

    Aicha Julia Llamos Paneque

    2007-03-01

    Full Text Available La alfafetoproteína es una glicoproteína específica del plasma fetal, cuya determinación en suero materno se realiza entre las 15 y 19 semanas de gestación. Para conocer el comportamiento del programa alfafetoproteína-ultrasonido genético en el municipio 10 de Octubre se realizó esta investigación. En ella se encontró que 862 gestantes presentaron alfafetoproteína elevada en suero materno en el período analizado, y las principales causas encontradas dependientes de la madre fueron: el error en la fecha de última menstruación, seguida de la amenaza de aborto; y las malformaciones congénitas más frecuentemente encontradas fueron los defectos de cierre del tubo neural, seguidos de las malformaciones cardiovasculares.The alpha-fetoprotein is a specific glycoprotein of the fetal plasma, whose determination in maternal serum is performed from the 15th to the 19th week of gestation. This research was conducted to know the behavior of the alpha-fetoprotein-genetic ultrasound program in “10 de Octubre” municipality. It was found that 108 pregnant women presented elevated alpha-fetoprotein in maternal serum during the analyzed period. The main causes depending on the mother were: error in the date of the last menstruation and threatened abortion. The most frequent congenital malformations were the defects of the neural tube closure, and the cardiovascular malformations.

  10. Numerical Analysis of Storm Surge and Seiche at Tokyo Bay caused by the 2 Similar Typhoons, Typhoon Phanphon and Vongfong in 2014

    Science.gov (United States)

    Iwamoto, T.; Takagawa, T.

    2017-12-01

    A long period damped oscillation, or seiche, sometimes happens inside a harbor after passing typhoon. For some cases, a maximum sea level is observed due to the superposition of astronomical tide and seiche rather than a peak of storm surge. Hence to clarify seiche factors for reducing disaster potential is important, a long-period seiche with a fundamental period of 5.46 hours in Tokyo Bay (Konishi, 2008) was investigated through numerical simulations and analyses. We examined the case of Typhoon Phanphon and Vongfong in 2014 (Hereafter Case P and V). The intensity and moving velocity were similar and the best-tracks were an arc-shaped, typical one approaching to Tokyo Bay. The track of Case V was about 1.5 degree higher latitude than that of Case P, only Typhoon Phanphon caused significant seiche.Firstly, numerical simulations for the 2 storm surges at Tokyo Bay were conducted by Regional Ocean Modeling System (ROMS) and Meso-Scale Model Grid Point Values (MSM-GPV). MSM-GPV gave the 10m wind speed and Sea Level Pressure (SLP), especially the Mean Error (ME) and Root Mean Squire Error (RMSE) of SLP were low compared to the 12 JMA observation points data (Case P: ME -0.303hPa, RMSE 1.87hPa, Case V: ME -0.285hPa, RMSE 0.74hPa). The computational results showed that the maximum of storm surge was underestimated but the difference was less than 20cm at 5 observation points in Tokyo Bay(Fig.1, 2).Then, power spectrals, coherences and phase differences of storm surges at the 5 observation points were obtained by spectral analysis of observed and simulated waveforms. For Case P, the phase-difference between the bay mouth and innermost part of Tokyo Bay was little, and coherence was almost 1(Fig.3, 4). However, for Case V, coherence was small around the fundamental period of 5.46 hours. Furthermore, Empirical Orthogonal Function (EOF) analysis of storm surge, SLP and sea surface stress were conducted. The contributions of EOF1 were above 90% for the all variables, the

  11. Epidemiología y registro de las cardiopatías congénitas en Costa Rica Epidemiology and registry of congenital heart disease in Costa Rica

    Directory of Open Access Journals (Sweden)

    Adriana Benavides-Lara

    2011-07-01

    Full Text Available OBJETIVO: Caracterizar la población de niños que nacen con cardiopatías congénitas (CC en Costa Rica y evaluar sus procesos de registro. MÉTODOS: Estudio observacional exploratorio que incluyó a todos los niños con CC diagnosticadas en el Hospital Nacional de Niños entre el 1 de mayo de 2006 y el 1 de mayo de 2007. Tomando en cuenta los niños menores de 1 año y su respectiva cohorte de nacimientos, se estimaron prevalencias con intervalos de confianza de 95% (IC95% según sexo, tipo de cardiopatía, edad al diagnóstico, edad materna, residencia habitual y malformaciones extracardiacas asociadas. Se compararon los datos con el Centro de Registro de Enfermedades Congénitas (CREC. RESULTADOS: Durante el período estudiado se diagnosticaron 534 casos con CC. Los casos en menores de 1 año fueron 473 dentro de una cohorte de nacimientos de 77 140 -prevalencia de 0,6% (IC95%: 0,5-0,7. Con base en datos del CREC, se demostró que al nacimiento no se detectan 71% de los casos. La edad promedio al diagnóstico en niños menores de 1 año fue de 46,6 días. No hubo diferencias por sexo. La prevalencia de CC en hijos de madres de 35 años o más fue significativamente mayor, aunque al excluir las cromosomopatías este riesgo perdió su significancia estadística. Las provincias del país con puertos marítimos fueron las de mayor riesgo en hijos de madres adolescentes. Las CC más frecuentes fueron los defectos del tabique interventricular e interauricular, persistencia del conducto arterioso, estenosis valvular pulmonar, defectos del tabique aurículo ventricular, coartación de aorta y tetralogía de Fallot. El 34% de las CC fueron múltiples, 11,2% se asociaron a cromosomopatías y 19% tenían malformaciones congénitas asociadas. CONCLUSIONES: La prevalencia de CC en Costa Rica está dentro del rango informado a nivel mundial. Se halló que en el CREC había un importante subregistro de CC debido principalmente a los criterios de edad

  12. Environmental radiation status of the University of Tokyo after the TEPCO Fukushima Dai-ichi nuclear power plant disaster

    International Nuclear Information System (INIS)

    Iimoto, Takeshi; Nogawa, Norio; Mitani, Hiroshi; Kamiko, Masao; Kutsuna, Natsumaro; Watanabe, Yasuhiro; Suzuki, Takahiko

    2013-01-01

    The University of Tokyo campuses are primarily located in the metropolitan area of Tokyo, Japan. The three main university campuses are the Hongo campus and the Komaba campus, located in the mideastern part of Tokyo prefecture, and the Kashiwa campus, located in the north western part of Chiba prefecture. The distance between the Fukushima Dai-ichi nuclear power plant and these three campuses ranges from ∼200 to ∼250 km. Immediately after the nuclear disaster, the university organized a special correspondence team to survey the environmental radiation status for the university. The team consists of about 20 members, including mostly radiation protection specialists or technical experts of the university specialized in radiation measurements. This project is not research-oriented; rather, the purpose is to provide, in the absence of related information, the actual data on environmental radiation immediately after the accident. This information is provided both to the members of the university community and to the public. The two primary measured quantities are (1) the ambient radiation dose (microsieverts per hour) and (2) the specific radioactivity (becquerels per kilogram) of soil around the surface of a ground, which is used to indicate the level of contamination. The ambient dose data were reported every day on the web site and the portal site magazine of the university, and soil contamination data were reported occasionally. This report provides the background status and technical information on the related activities. In addition, it documents the measured environmental radiation data. Temporal variation of the ambient radiation dose rate had been officially surveyed since the morning of March 15, 2011, at the selected representative locations on the campus sites. In addition, maps were drawn that showed the distribution area of the ambient dose rate of three campuses. The first peak dose of 0.72 μSv h -1 was observed at ∼2:30 pm on May 15, 2011, in the

  13. Newborn screening for congenital adrenal hyperplasia in Tokyo, Japan from 1989 to 2013: a retrospective population-based study.

    Science.gov (United States)

    Tsuji, Atsumi; Konishi, Kaoru; Hasegawa, Satomi; Anazawa, Akira; Onishi, Toshikazu; Ono, Makoto; Morio, Tomohiro; Kitagawa, Teruo; Kashimada, Kenichi

    2015-12-15

    Congenital adrenal hyperplasia (CAH) cause life-threatening adrenal crisis. It also affects fetal sex development and can result in incorrect sex assignment at birth. In 1989, a newborn screening program for congenital adrenal hyperplasia (CAH) was introduced in Tokyo. Here we present the results of this screening program in order to clarify the efficiency of CAH screening and the incidence of CAH in Japan. From 1989 to 2013, a total of 2,105,108 infants were screened for CAH. The cutoff level for diagnosis of CAH was adjusted for gestational age and birth weight. A total of 410 infants were judged positive, and of these, 106 patients were diagnosed with CAH, indicating a positive predictive value (PPV) of 25.8 %. Of the 106 patients, 94 (88.7 %) were diagnosed with 21-OHD. Of these 94 patients, 73 were diagnosed with the salt wasting form, 14 with the simple virilising form and 7 with the nonclassical form (NC21OHD). The mean birth weight and gestational age were 3192 ± 385 g and 38.9 ± 1.38 weeks. 11 out of 44 female patients were assigned as female according to their screening result. These data suggest that the newborn screening in Tokyo was effective, especially for sex assignment and preventing fatal adrenal crisis. The incidence of CAH was similar to that measured in previous Japanese screening studies, and it was also similar to that of western countries. The incidence of NC21OHD in Japan in the present study was lower than that in western countries as previous studies reported. The screening program achieved higher PPV than previous CAH screening studies, which might be due to the use of variable cutoffs according to gestational age and birth weight. However, most of the neonates born at 37 weeks or less that were referred to hospital were false-positives. Further changes are needed to reduce the number of false positive preterm neonates.

  14. [Identification of Psychotropic Drugs Attributed to Fatal Overdose--A Case-control Study by Data from the Tokyo Medical Examiner's Office and Prescriptions].

    Science.gov (United States)

    Hikiji, Wakako; Okumura, Yasuyuki; Matsumoto, Toshihiko; Tanifuji, Takanobu; Suzuki, Hideto; Takeshima, Tadashi; Fukunaga, Tatsushige

    2016-01-01

    Drug overdose is a serious public health issue and fatal cases have been reported from various fields of medicine. This case-control analysis assessed the comparison between fatal overdose cases in the special wards of Tokyo Metropolitan area and prescribed psychotropic drugs in Tokyo in 2009-2010. It was suggested that the prescribed drugs serve as a direct cause of death in overdose cases. Furthermore, pentobarbital calcium, chlorpromazine-promethazine-phenobarbital, levomepromazine and flunitrazepam were identified as drugs with a high risk of fatal overdose. It is encouraged to prudently verify the intended application and usage of such psychotropic drugs in each case upon their prescription. This is the first study in Japan to identify psychotropic drugs with a high risk of fatal overdose by case-control study.

  15. Main findings and summary of answers from the regulators' forum questionnaire on regulation for geologic disposal. Support document to the Tokyo workshop, 20-22 January 2009

    International Nuclear Information System (INIS)

    2008-01-01

    The last decade has seen significant progress in several countries on the siting of repositories for deep disposal of long-lived radioactive waste. In parallel with this, regulatory authorities have developed and expanded the regulations that will be applied, firstly in deciding applications to proceed with repository development and, secondly, to provide the basis for ongoing supervision of repository development work. A workshop to be held in Tokyo 20-22 January 2009 will examine current issues in regulation for geological disposal of long-lived radioactive waste. A questionnaire was developed and sent to regulatory organisations in order to collect relevant data and structure the workshop along the themes of highest interest. The questionnaire answers are summarised herein along with the main findings in order to inform the discussions that will be held in the Tokyo workshop. (authors)

  16. Visit of Professor Shigehiko Hasumi. President of Tokyo University, Japan, Professor Kazuo Okamoto, Head of Graduate School of Mathematical Sciences, Professor Toshiteru Matsuura, Head of Graduate School of Arts and Sciences

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    Visit of Professor Shigehiko Hasumi. President of Tokyo University, Japan, Professor Kazuo Okamoto, Head of Graduate School of Mathematical Sciences, Professor Toshiteru Matsuura, Head of Graduate School of Arts and Sciences

  17. Temperature profile data collected using XBTs from the TOKYO MARU and other platforms from the Pacific Ocean during the Thermal Structure Monitoring Program in the Pacific (TRANSPAC) project, 1989-08-28 to 1990-07-08 (NODC Accession 9000204)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile data were collected using bathythermograph (BT/XBT) casts from TOKYO MARU and other platforms in the Pacific Ocean from August 28, 1989 to July...

  18. Multifactorial logistic regression analysis of factors associated with the incidence of erosive tooth wear among adults at different ages in Tokyo.

    Science.gov (United States)

    Kitasako, Yuichi; Sasaki, Y; Takagaki, T; Sadr, A; Tagami, J

    2017-11-01

    The aim of this study was to evaluate factors associated with the incidence of erosive tooth wear (ETW) among adults at different ages in Tokyo using multifactorial logistic regression analysis. The study sample consisted of a total of 1108 subjects aged 15 to 89 years in Tokyo, Japan. Two examiners evaluated ETW in a full-mouth recording. The subjects were asked to complete a self-administered daily diet, habit, and health condition questionnaire. Subjects who had frequent acid consumption or gastric reflux and at least one tooth with initial enamel wear were placed in the ETW-positive group, and the remainder of the subjects was placed in the ETW-negative group. Logistic regression analyses were carried out to identify factors collectively associated with ETW. Logistic regression analysis showed that greater frequencies of carbonated or sports drink consumption were associated with higher incidence of ETW for all age groups except for 70-89 years. Adults in the 30-39-year group who reported suffering from heartburn were about 22.3 times more likely to develop ETW, while 40-49-year adults who had repeated vomiting were about 33.5 times more likely to exhibit ETW compared with those who did not experience vomiting. Age-specific dietary habits were clearly observed among adults at different ages in Tokyo, and there were significant differences in intrinsic and extrinsic factors between ETW-positive and ETW-negative groups for each age group. Both greater frequency of carbonated and sports drink consumption were associated with higher incidence of ETW among adults at different ages in Tokyo.

  19. Marine integrons containing novel integrase genes, attachment sites, attI, and associated gene cassettes in polluted sediments from Suez and Tokyo Bays.

    Science.gov (United States)

    Elsaied, Hosam; Stokes, Hatch W; Kitamura, Keiko; Kurusu, Yasurou; Kamagata, Yoichi; Maruyama, Akihiko

    2011-07-01

    In order to understand the structure and biological significance of integrons and associated gene cassettes in marine polluted sediments, metagenomic DNAs were extracted from sites at Suez and Tokyo Bays. PCR amplicons containing new integrase genes, intI, linked with novel gene cassettes, were recovered and had sizes from 1.8 to 2.5 kb. This approach uncovered, for the first time, the structure and diversity of both marine integron attachment site, attI, and the first gene cassette, the most efficiently expressed integron-associated gene cassette. The recovered 13 and 20 intI phylotypes, from Suez and Tokyo Bay samples, respectively, showed a highly divergence, suggesting a difference in integron composition between the sampling sites. Some intI phylotypes showed similarity with that from Geobacter metallireducens, belonging to Deltaproteobacteria, the dominant class in both sampling sites, as determined by 16S rRNA gene analysis. Thirty distinct families of putative attI site, as determined by the presence of an attI-like simple site, were recovered. A total of 146 and 68 gene cassettes represented Suez and Tokyo Bay unsaturated cassette pools, respectively. Gene cassettes, including a first cassette, from both sampling sites encoded two novel families of glyoxalase/bleomycin antibiotic-resistance protein. Gene cassettes from Suez Bay encoded proteins similar to haloacid dehalogenases, protein disulfide isomerases and death-on-curing and plasmid maintenance system killer proteins. First gene cassettes from Tokyo Bay encoded a xenobiotic-degrading protein, cardiolipin synthetase, esterase and WD40-like β propeller protein. Many of the first gene cassettes encoded proteins with no ascribable function but some of them were duplicated and possessed signal functional sites, suggesting efficient adaptive functions to their bacterial sources. Thus, each sampling site had a specific profile of integrons and cassette types consistent with the hypothesis that the

  20. Comparison of Toxoplasma gondii Seroprevalence in Shelter Cats and Dogs during 1999-2001 and 2009-2011 in Tokyo, Japan.

    Directory of Open Access Journals (Sweden)

    Masaaki Oi

    Full Text Available Toxoplasma gondii is an important human health concern with respect to abortion, congenital hydrocephalus, and encephalitis in immunocompromised people. Cats and dogs both are potential sources of T. gondii because they have close contact with humans. However, no epidemiological surveys have been conducted in Tokyo over the past decade. Therefore, the present study investigated and compared the seroprevalence of T. gondii infection in shelter cats and dogs during 1999-2001 and 2009-2011 in Tokyo, Japan. Serum samples were collected from 337 shelter cats and 325 shelter dogs in urban and suburban areas of Tokyo, during 1999-2001 (233 cats and 219 dogs and 2009-2011 (104 cats and 106 dogs. T. gondii antibodies were measured in the serum samples using a commercial latex agglutination test. Data were compared using the Fisher's exact test, and significance was indicated at P < 0.05. The overall seroprevalence of T. gondii infection in cats was 5.6% (13 of 233 in 1999-2001 and 6.7% (7 of 104 in 2009-2011, and that in dogs was 1.8% (4 of 219 and 1.9% (2 of 106, respectively. Significantly higher seroprevalence was observed in cats from suburban areas compared with cats in urban areas during both periods (P < 0.05. These results reveal that there has been little change in the feline and canine seroprevalence over the past decade, indicating that the risk of T. gondii exposure for cats and dogs in Tokyo is considerably low as the seroprevalence has reached a steady state.

  1. The bases of development and characteristics of market gardening in tokyo metropolis : a case study of kanahori area of tomisato town, chiba prefecture

    OpenAIRE

    Zhang, Gui-Min

    1994-01-01

    In this paper an attempt is made by focussing on the farming at the urban fringe of Tokyo, to consider the bases of development and the characteristics of the formation of market gardening and examine the internal farming factors in Kanahori area of Tomisato Town, Chiba Prefecture. The results are summarized as follows. In Kanahori area, there are many full-time farms. The farms make an intensive farming and establish market gardening farming in group. Numerous family farming workers are full...

  2. Book Review: Backhaus, Peter (2007): Linguistic Landscapes: A Comparative Study of Urban Multilingualism in Tokyo. Clevedon: Multilingual Matters; 158 Pages ISBN 9781853599460

    OpenAIRE

    Omar Alomoush

    2015-01-01

    Backhaus examines urban multilingualism in the linguistic landscape of Tokyo, the capital city of Japan. In this monograph, the linguistic landscape is seen as a sub-discipline of sociolinguistics. The significance of this monograph to linguistic landscape research is that it represents the first comprehensive approach tackling multilingualism in the linguistic landscape and overcoming a range of methodological problems facing former studies. In this sense, Backhaus’s approach in data collect...

  3. Report of the second joint Research Committee for Fusion Reactor and Materials. July 12, 2002, Tokyo, Japan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-05-01

    Joint research committees in purpose of the discussion on DEMO blanket in view point of the both of reactor technology and materials were held by the Research Committee for Fusion Reactor and Fusion Materials. The joint research committee was held in Tokyo on July 12, 2002. In the committee, the present status of development of solid and liquid breeding blanket, the present status of development of reduced activation structure materials, and IFMIF (International Fusion Materials Irradiation Facility) program were discussed based on the discussions of the development programs of the blanket and materials at the first joint research committee. As a result, it was confirmed that high electric efficiency with 41% would be obtained in the solid breeding blanket system, that neutron radiation data of reduced activation ferritic steel was obtained by HFIR collaboration, and that KEP (key element technology phase) of IFMIF would be finished at the end of 2002 and the data base for the next step, i.e. EVEDA (engineering validation/engineering design activity) was obtained. In addition, the present status of ITER CTA, which was a transient phase for the construction, and the outline of ITER Fast Track, which was an accelerated plan for the performance of the power plants, were reported. This report consists of the summary of the discussion and the viewgraphs which were used at the second joint research committee, and these are very useful for the researchers of the fusion area in Japan. (author)

  4. Clinical survey over the past 35 years at the clinic for maxillofacial prosthetics Tokyo Medical and Dental University.

    Science.gov (United States)

    Yanagi, Ayaka; Sumita, Yuka; Hattori, Mariko; Kamiyanagi, Ayuko; Otomaru, Takafumi; Kanazaki, Ayako; Haraguchi, Mihoko; Murase, Mai; Hatano, Noriko; Taniguchi, Hisashi

    2018-01-29

    The purpose of this survey was to examine the overview of maxillofacial prosthetic treatment at our department, in order to ascertain the actual status of patients and discuss future needs. Subjects were all patients who visited Clinic for Maxillofacial Prosthetics, Dental Hospital, Tokyo Medical and Dental University (TMDU) in the period from January 1, 1980 to December 31, 2014. Using medical records of the Clinic for Maxillofacial Prosthetics, Dental Hospital, TMDU, patients' data including sex, address, referring institution, and primary condition were analyzed throughout the period. The number of patients over 35 years was 6219, with a man-to-woman ratio of 6:4. The number of patients in their 60s, 70s, and 80s showed an increasing trend. Patients with tumors accounted for about 50 % of cases in 1980-1984 and increased to 80 % in 2010-2014. The survey showed an increasing number of elderly patients and patients with tumors. This suggests that more awareness and education about maxillofacial prosthetics are needed. Copyright © 2018 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  5. Report of the research results with University of Tokyo, Nuclear Engineering Research Laboratory's Facilities in fiscal 1983

    International Nuclear Information System (INIS)

    1984-01-01

    Much achievement was obtained also in fiscal 1983 by the common utilization of the nuclear reactor ''Yayoi'' and the linear accelerator in the Nuclear Engineering Research Laboratory, University of Tokyo. These results were summarized, and this report is published. In the utilization of the reactor ''Yayoi'', the period of operation and the maximum output were limited very much, because long cooling period is necessary to prepare for the repair of fuel cladding in the next year. Also foreign research students commonly utilized the reactor ''Yayoi''. The common utilization of the linear accelerator was begun six years ago, and now it is carried out widely and smoothly. The total number of those who commonly utilized the facilities reached 3,179. The summaries of the results of 5 on-pile researches, 17 off-pile researches, and 16 researches using the linear accelerator are collected. The committee meetings and study meetings held in fiscal 1983 are listed. The names of the members of various committees and the names of those in charge of various experiments are given. (Kako, I.)

  6. An intervention analysis on the Tokyo Grain Exchange non-genetically modified and conventional soybean futures markets

    Directory of Open Access Journals (Sweden)

    Kentaka Aruga

    2014-12-01

    Full Text Available This paper examines how efficiently the price premium for non-genetically modified (non-GM soybeans at the Tokyo Grain Exchange (TGE reacts to an announcement to change the contract unit, suppliers, and expiration date on the conventional soybean futures contract. An intervention analysis is used for this purpose. The results reveal that the price premium for non-GM soybeans increases after the change and this effect did not disappear immediately. This implies that the two soybean futures markets did not respond quickly to the announcement and there was an informational inefficiency after the announcement. The TGE non-GM soybean futures market is one of the first segregated markets for a non-GM commodity. An intervention of clearing houses on such newly opened markets can often lead to market inefficiency so a further study is necessary in order to understand what causes such inefficiency and to find out how clearing houses can minimize the effects of intervention.

  7. Seroprevalence of Pandemic 2009 (H1N1) Influenza A Virus among Schoolchildren and Their Parents in Tokyo, Japan▿

    Science.gov (United States)

    Iwatsuki-Horimoto, Kiyoko; Horimoto, Taisuke; Tamura, Daisuke; Kiso, Maki; Kawakami, Eiryo; Hatakeyama, Shuji; Ebihara, Yasuhiro; Koibuchi, Tomohiko; Fujii, Takeshi; Takahashi, Kazuo; Shimojima, Masayuki; Sakai-Tagawa, Yuko; Ito, Mutsumi; Sakabe, Saori; Iwasa, Ayaka; Takahashi, Kei; Ishii, Takashi; Gorai, Takeo; Tsuji, Koichiro; Iwamoto, Aikichi; Kawaoka, Yoshihiro

    2011-01-01

    Since its emergence, the 2009 pandemic H1N1 virus has spread rapidly throughout the world. Previously, we reported that most individuals born after 1920 do not have cross-reactive virus-neutralizing antibodies against pandemic (H1N1) 2009 virus, indicating that they were immunologically naïve to the pandemic virus prior to its emergence. This finding provided us with an excellent opportunity for a seroepidemiological investigation of the transmission mode of the pandemic virus in the community. To gain insight into its transmission within communities, we performed a serosurvey for pandemic virus infection with schoolchildren at an elementary school in Tokyo, Japan, and their parents. We observed a high prevalence of neutralizing antibodies to the pandemic virus in the children at this school, although the percentage of children positive for the neutralizing antibodies varied among classrooms. While a much lower prevalence was observed among parents, seropositivity of the parents correlated with that of their schoolchildren. Moreover, many adults appeared to have experienced asymptomatic infection with the pandemic virus. These data suggest that the pandemic virus was readily transmitted among schoolchildren in elementary schools and that it was also transmitted from schoolchildren to their parents. PMID:21346056

  8. Isolation and characterization of benzo[a]pyrene-degrading bacteria from the Tokyo Bay area and Tama River in Japan.

    Science.gov (United States)

    Okai, Masahiko; Kihara, Ikumi; Yokoyama, Yuto; Ishida, Masami; Urano, Naoto

    2015-09-01

    Benzo[a]pyrene (BaP) is one of the polycyclic aromatic hydrocarbons, and has serious detrimental effects on human health and aquatic environments. In this study, we isolated nine bacterial strains capable of degrading BaP from the Tokyo Bay area and Tama River in Japan. The isolated bacteria belonged to the phyla Actinobacteria, Firmicutes, Proteobacteria and Bacteroidetes, indicating that the BaP-degrading bacteria were widely present in the hydrosphere. ITB11, which shared 100% 16S rRNA identity with Mesoflavibacter zeaxanthinifaciens in the phylum Bacteroidetes, showed the highest degradation of BaP (approximately 86%) among the nine isolated strains after 42 days. Moreover, it was found that three of the nine isolated strains collectively removed 50-55% of BaP during the first 7 days. Growth measurement of M. zeaxanthinifaciens revealed that the strain utilized BaP as a sole carbon and energy source and salicylate acted only as an inducer of BaP degradation. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Spotting Epidemic Keystones by R0 Sensitivity Analysis: High-Risk Stations in the Tokyo Metropolitan Area.

    Science.gov (United States)

    Yashima, Kenta; Sasaki, Akira

    2016-01-01

    How can we identify the epidemiologically high-risk communities in a metapopulation network? The network centrality measure, which quantifies the relative importance of each location, is commonly utilized for this purpose. As the disease invasion condition is given from the basic reproductive ratio R0, we have introduced a novel centrality measure based on the sensitivity analysis of this R0 and shown its capability of revealing the characteristics that has been overlooked by the conventional centrality measures. The epidemic dynamics over the commute network of the Tokyo metropolitan area is theoretically analyzed by using this centrality measure. We found that, the impact of countermeasures at the largest station is more than 1,000 times stronger compare to that at the second largest station, even though the population sizes are only around 1.5 times larger. Furthermore, the effect of countermeasures at every station is strongly dependent on the existence and the number of commuters to this largest station. It is well known that the hubs are the most influential nodes, however, our analysis shows that only the largest among the network plays an extraordinary role. Lastly, we also found that, the location that is important for the prevention of disease invasion does not necessarily match the location that is important for reducing the number of infected.

  10. Shedding of Rubella Virus among Infants with Congenital Rubella Syndrome Born in Tokyo, Japan, 2013-2014.

    Science.gov (United States)

    Sugishita, Yoshiyuki; Akiba, Tetsuya; Sumitomo, Masami; Hayata, Noriko; Hasegawa, Michiya; Tsunoda, Tokuko; Okazaki, Terue; Murauchi, Konomi; Hayashi, Yukinao; Kai, Akemi; Seki, Naomi; Kayebeta, Aya; Iwashita, Yuuko; Kurita, Masayuki; Tahara, Narumi

    2016-09-21

    Rubella is usually a mild illness, with febrile rash being its main symptom. However, serious consequences of rubella infection can result when the infection occurs during the early stages of pregnancy. After the occurrence of a rubella outbreak in Japan that was observed from 2012 to 2013, 45 infants were reportedly born with congenital rubella syndrome (CRS). We prospectively followed the 15 CRS cases reported in Tokyo to determine the virus shedding periods by using nested reverse transcriptase-polymerase chain reaction to detect rubella virus genes. Throast swabs were used for virus detection. The virus shedding period was measured from birth until the time when the sample last tested positive followed by 2 consecutive negative samples. Kaplan-Meier method was used to estimate the proportion of cases remaining positive for rubella virus genes over time. The proportion of CRS cases shedding virus dropped steadily after birth, dropping to 33.8% at 6 months and 16.9% at 12 months. Our findings also suggested that the earlier the mother's onset of rubella during pregnancy, the longer the infant remained positive. Based on our findings, we believe that infants with CRS should be monitored for rubella virus shedding until 1 year of age.

  11. Analysis of Needlestick and Similar Injuries over 10 Years from April 2004 at Tokyo Dental College Chiba Hospital.

    Science.gov (United States)

    Morinaga, Kazuki; Hagita, Keiko; Yakushiji, Takashi; Ohata, Hitoshi; Sueishi, Kenji; Inoue, Takashi

    2016-01-01

    Here we investigated needlestick and similar injuries reported over a 10-year period between April 2004 and March 2014. The purpose of this study was to prevent recurrence and reduce the incidence of such injuries at Tokyo Dental College Chiba Hospital. The Division of Medical Risk Management at Chiba Hospital anonymized the data to protect personal information prior to analysis. A total of 213 injuries occurred over the 10-year period investigated, but the number of cases decreased yearly. Many cases involved dental undergraduate students and dentists, followed by trainee dentists, students at the school of dental hygiene, nurses, dental hygienists, and cleaners. Suture needles, followed by injection needles, were the top two most common injury-causing instruments, contributing to approximately 50% of the total number of such cases. Many injection needle injuries occurred during tidying up, while those caused by suture needles occurred during dental treatment. Taken together, these findings suggest the importance of strict adherence to guidelines provided in safety manuals on error-free procedures and handling of instruments. Improvement in the ability to sense potential risk is essential if such injuries are to be avoided.

  12. Nontarget approach for environmental monitoring by GC × GC-HRTOFMS in the Tokyo Bay basin.

    Science.gov (United States)

    Zushi, Yasuyuki; Hashimoto, Shunji; Tanabe, Kiyoshi

    2016-08-01

    In this study, we developed an approach for sequential nontarget and target screening for the rapid and efficient analysis of multiple samples as an environmental monitoring using a comprehensive two-dimensional gas chromatograph coupled to a high resolution time-of-flight mass spectrometer (GC × GC-HRTOFMS). A key feature of the approach was the construction of an accurate mass spectral database learned from the sample via nontarget screening. To enhance the detection power in the nontarget screening, a global spectral deconvolution procedure based on non-negative matrix factorization was applied. The approach was applied to the monitoring of rivers in the Tokyo Bay basin. The majority of the compounds detected by the nontarget screening were alkyl chain-based compounds (55%). In the quantitative target screening based on the output from the nontarget screening, particularly high levels of organophosphorus flame retardants (median concentrations of 31, 116 and 141 ng l(-1) for TDCPP, TCIPP and TBEP, respectively) were observed among the target compounds. Flame retardants used for household furniture and building materials were detected in river basins where buildings and arterial traffic were dominated. The developed GC × GC-HRTOFMS approach was efficient and effective for environmental monitoring and provided valuable new information on various aspects of monitoring in the context of environmental management. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Impact of the mobile phone on junior high-school students' friendships in the Tokyo metropolitan area.

    Science.gov (United States)

    Kamibeppu, Kiyoko; Sugiura, Hitomi

    2005-04-01

    The proportion of having keitai (Japanese mobile phone) has increased rapidly in young children. To research how junior high school students use their own keitai and to examine the impact of using it on their psychology, especially on their friendship, we recruited 651 students, grade 8, from five public junior high schools in the Tokyo metropolitan area. Each student participant completed a questionnaire that we had created. The response rates were 88.8% (n = 578) for participants. The proportion of having their own keitai was 49.3% (n = 285) and that of not having it was 50.7% (n = 293). We found that they used it much more frequently for e-mail than as a phone. Most of them exchanged e-mails between schoolmates, and more than a half of them exchanged e-mails more than 10 times a day. Sociable students estimated that their own keitai was useful for their friendship. But they experienced some insecurity or started staying up late at night engaged in e-mail exchanges, and they thought that they could not live without their own keitai. Our findings suggest that keitai having an e-mail function play a big part in the junior high-school students' daily life, and its impact on students' friendships, psychology, or health should be discussed among students to prevent keitai addiction.

  14. Factors Affecting Initial Intimate Partner Violence-Specific Health Care Seeking in the Tokyo Metropolitan Area, Japan.

    Science.gov (United States)

    Kamimura, Akiko; Bybee, Deborah; Yoshihama, Mieko

    2014-09-01

    This study examined the factors affecting a women's initial intimate partner violence (IPV)-specific health care seeking event which refers to the first health care seeking as a result of IPV in a lifetime. Data were collected using the Life History Calendar method in the Tokyo metropolitan area from 101 women who had experienced IPV. Discrete-time survival analysis was used to assess the time to initial IPV-specific health care seeking. IPV-related injury was the most significant factor associated with increased likelihood of seeking IPV-specific health care seeking for the first time. In the presence of a strong effect of formal help seeking, physical and sexual IPV were no longer significantly related to initial IPV-specific health care seeking. The results suggest some victims of IPV may not seek health care unless they get injured. The timing of receiving health care would be important to ensure the health and safety of victims. © The Author(s) 2014.

  15. Growing electricity demand and role of nuclear power in Asia. WANO Tokyo Center summarizes Asian Nuclear Power Atlas

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    Present status of the activities of World Association of Nuclear Operations (WANO) in Asia was briefly summarized here. The WANO Tokyo Center is the hub for WANO's activities having a member ship of 17 operators from six countries and territories. The center conducts a variety of activities designed to enhance the safety and reliability of nuclear power plants (NPPs) in Asia. Asian economy is expanding now in spite of the stagnation of recent world economy. The economic development has been paralleled by population growth in Asia and the 21st century may become the 'age of Asia'. Despite this remarkable economic growth, some parts of Asia are still at the developing stage in terms of electric power infrastructure. Demand for electric power is expected to increase dramatically from now on, making the development of electric power plants an urgent priority. Nuclear power has thus become the focus of increasing interest in Asia. At present, 17 operators in six countries of Asia operate 79 units at 32 power stations with a total capacity of approximately 60 GW, or equivalent to around 17% of the total capacity of all WANO members. China's massive NPP construction program and Indonesia's nuclear power program are expected to boost total capacity in future. (M.N.)

  16. The impact of air pollutants on rainwater chemistry during "urban-induced heavy rainfall" in downtown Tokyo, Japan

    Science.gov (United States)

    Uchiyama, Ryunosuke; Okochi, Hiroshi; Katsumi, Naoya; Ogata, Hiroko

    2017-06-01

    In order to clarify the impact of air pollution on the formation of sudden and locally distributed heavy rain in urban areas (hereafter UHR = urban-induced heavy rain), we analyzed inorganic ions in rainwater samples collected on an event basis over 5 years from October 2012 to December 2016 in Shinjuku, Tokyo. Hourly rainfall amounts and wet deposition fluxes of acidic components (the sum of H+, NH4+, NO3-, and nonsea-salt SO42-) in UHR were 13.1 and 17.8 times larger than those in normal rainfall, respectively, indicating that large amount of air pollutants were scavenged and deposited by UHR with large amounts of rainfall. The level of air pollutants, such as NO2, SO2, and potential ozone, in the ambient air increased just before the formation of UHR and decreased sharply at the end of the UHR event. These results indicate that NO2, which was formed secondarily by oxidants, was further oxidized by HO radicals and formed HNO3 just before the formation of UHR, which was subsequently scavenged by UHR.

  17. Report of the research results with University of Tokyo, Nuclear Engineering Research Laboratory's Facilities in fiscal 1986

    International Nuclear Information System (INIS)

    1987-01-01

    This book contains a large number of reports of studies made in 1986 through joint utilization of the nuclear reactor 'Yayoi' and electron beam type accelerator which are installed in the Nuclear engineering Research Laboratory, Faculty of Engineering, University of Tokyo. The reports presented deal with 'Behaviors of Neutrons in Fast Reactor Blanket Shield', 'Effect of Fast Neutron Radiation on Organic Materials', 'Production and Recovery of Tritium in Nuclear Fusion Reactor Blanket System', 'Bench Mark Experiment of Effect of Atmospheric Scattering of Neutron', 'Experimental Evaluation of Nuclear Heat Rate', 'Fast Neutron Shielding Experiment', 'Effect of Fast Neutron Radiation on Hot Water', 'Neutron Shielding Experiment', 'Biological and Medical Application of 'Yayoi' Neutron', 'Effect of Fission-Fusion Correlation Radiation on Semiconductors (Si, GaAs)', 'Application of Fast Neutron to Radiography Technology', 'Streaming in Offset Slit', 'Design and Evaluation of New Reactor', 'LET Effect on Organic Material', 'Handling, Separation and Recovery of Transuranium Elements', 'Reactor Operation Support System Using Knowledge Engineering Technique', 'Application of Shape Memory Alloys to Nuclear Reactor Devices', 'Numerical Simulation of Turbulent Hear Transfer', and many other studies. (Nogami, K.)

  18. Live broadcast lectures on complete denture prosthodontics at Tokyo Medical and Dental University: comparison of two years.

    Science.gov (United States)

    Iwaki, Maiko; Kanazawa, Manabu; Sunaga, Masayo; Kinoshita, Atsuhiro; Minakuchi, Shunsuke

    2013-03-01

    A live broadcasting system was developed as part of dental education with Information and Communication Technology (ICT) at Tokyo Medical and Dental University. The purpose of this study was to utilize this system in complete denture prosthodontics, especially for the procedure of making a definitive impression with custom tray border molding in edentulous patients, and to evaluate its effectiveness. Live broadcast lectures on complete denture prosthodontics were given to fourth-year students in 2009 (fifty-nine students) and in 2010 (sixty-five students). To evaluate this lecture, a questionnaire was distributed to the students and faculty members after the lecture. Almost all the students and faculty members rated the lecture as good. Students commented that the lecture was "intelligible," "inspiring," "improved understanding," "good because they could ask questions in real time," "helped to know the actual time," "good for all the students to see the same case," and "close to real experience and induced a sense of tension." The results of this study suggested that a live broadcast lecture would help students experience the real clinical situation and aid in teaching complete denture prosthodontics.

  19. Catheter replacement structure in home medical care settings and regional characteristics in Tokyo and three adjoining prefectures.

    Science.gov (United States)

    Kimura, Takuma; Yoshie, Satoru; Tsuchiya, Rumiko; Kawagoe, Shohei; Hirahara, Satoshi; Iijima, Katsuya; Akahoshi, Toru; Tsuji, Tetsuo

    2017-04-01

    The present study investigated the association between the structure of catheter replacement services in home medical care settings and regional characteristics. An anonymous self-administered questionnaire was carried out from August to September 2013. Participants were physicians from 5338 clinics that provided medical care services at home, and nurses from 1619 home-visit nursing stations in Tokyo and three adjoining prefectures. The questionnaire covered catheter replacement (gastrostomy tubes, nasogastric tubes, tracheal cannulas) during home medical care, and the professions of those who replaced urethral catheters for male and female patients. Regions were divided into two groups (higher- and lower-density regions) based on the number of clinics, number of home-visit nursing stations and the ratio of the population aged ≥65 years. The rates of respondents that reported catheter replacement was usually executed, and those who reported catheters were replaced by "physicians in principle" were compared between the groups. Responses were received from 842 clinics (16.3%) and 499 home-visit nursing stations (31.4%). In the higher-density regions, the rate of physicians who reported urethral catheters for male patients were replaced by "physicians in principle" was significantly higher than in the lower-density regions (P home medical care settings, urethral catheters for male patients are replaced by nurses in regions where physician resources are limited. Geriatr Gerontol Int 2017; 17: 628-636. © 2016 Japan Geriatrics Society.

  20. Report from investigation committee on the accident at the Fukushima Nuclear Power Stations of Tokyo Electric Power Company

    International Nuclear Information System (INIS)

    Koshizuka, Seiichi

    2012-01-01

    Government's Investigation Committee on the Accident at Fukushima Nuclear Power Stations of Tokyo Electric Power Company published its final report on July 23, 2012. Results of investigation combined final report and interim report published on December 26, 2011. The author was head of accident accuse investigation team mostly in charge of site response, prior measure and plant behavior. This article reported author related technical investigation results focusing on site response and prior measures against tsunamis of units 1-3 of Fukushima Nuclear Power Stations. Misunderstanding of working state of isolation condenser of unit 1, unsuitability of alternative water injection at manual stop of high-pressure coolant injection (HPCI) system of unit 3 and improper prior measure against tsunami and severe accident were pointed out in interim report. Improper monitoring of suppression chamber of unit 2 and again unsuitable work for HPCI system of unit 3 were reported in final report. Thorough technical investigation was more encouraged to update safety measures of nuclear power stations. (T. Tanaka)

  1. Identification of subjects for social responsibility education at universities and the present activity at the university of Tokyo.

    Science.gov (United States)

    Karima, Risuke; Oshima, Yoshito; Yamamoto, Kazuo

    2006-01-01

    The management of corporate social responsibility (CSR) has recently become a critical concern for companies in advanced countries. For universities, there is a requirement to contribute to the promotion of CSR, resulting in graduates who have sufficient cognition of and a good attitude towards CSR. In addition, universities have social responsibilities, which can be called "University Social Responsibility (USR)." On the basis of the concepts of the guidelines for CSR in the "Green Paper," which was presented by the European Committee (EC) in 2001, we provide a perspective here on what factors dictate the establishment of education programs for social responsibilities at universities. These factors include an outline of the concepts and the significance of CSR, social ethics and the morals of higher education and research, compliances, human resource management, human rights, safety and health in academic settings, and various concerns regarding environmental safety and preservation. Additionally, through the concept postulated here for social responsible education, in this paper, we introduce the present activity at the University of Tokyo (UT) in terms of the education program for CSR and USR, proposing that the future establishment of university-wide education programs based on the concept of CSR and the value of sustainability is required at UT.

  2. A Japanese-American Sam Spade: The Metaphysical Detective in Death in Little Tokyo, by Dale Furutani

    Directory of Open Access Journals (Sweden)

    Portilho Carla

    2017-06-01

    Full Text Available The aim of this essay is to discuss the legacy of the roman noir in contemporary detective fiction produced outside the hegemonic center of power, here represented by the novel Death in Little Tokyo (1996, written by Japanese-American author Dale Furutani. Starting from the concept of the metaphysical detective (Haycraft 76; Holquist 153-156, characterized by deep questioning about narrative, interpretation, subjectivity, the nature of reality and the limits of knowledge, this article proposes a discussion about how these literary works, which at first sight represent a traditionally Anglo-American genre, constitute narratives that aim to rescue the memory, history and culture of marginalized communities. Typical of late modernity detective fiction, the metaphysical detective has none of the positivistic detective’s certainties, as he does not share in his Cartesian notion of totality, being presented instead as a successor of the hardboiled detective of the roman noir. In this article I intend to analyze the paths chosen by the author and discuss how his re-reading of the roman noir dialogues with the texts of hegemonic noire detective fiction, inscribing them in literary tradition and subverting them at the same time.

  3. Radiation therapy for Kaposi's sarcoma associated with acquired immunodeficiency syndrome. Tokyo Metropolitan Komagome Hospital experience

    Energy Technology Data Exchange (ETDEWEB)

    Ebara, Takeshi [Municipal Kanbara General Hospital, Fujikawa, Shizuoka (Japan); Karasawa, Katsuyuki; Maebayashi, Katsuya; Kurosaki, Hiromasa; Ishikawa, Hitoshi; Kaizu, Toshihide; Tanaka, Yoshiaki; Akagi, Kumiko; Masuda, Gota

    2000-12-01

    Kaposi's sarcoma is frequently found in association with acquired immunodeficiency syndrome (AIDS). We report on radiotherapy for patients with AIDS-related Kaposi's sarcoma at Tokyo Metropolitan Komagome Hospital. Between April 1991 and May 1997, radiotherapy was given to 11 lesions in eight men with AIDS-related Kaposi's sarcoma to relieve their symptoms. The lesions involved the head and neck region, the legs, and the gastrointestinal tract. Radiotherapy was carried out with 4-MV photon through parallel opposed field or high energy electrons. Total doses ranged from 20 to 38 Gy, with a median of 30 Gy, delivered in 2- to 3-Gy fractions. Four patients were given other treatments prior to the radiotherapy. Acute reaction was evaluated according to the modified acute radiation morbidity scoring criteria of the Radiation Therapy Oncology Group (RTOG). Radiotherapy had relieved the symptoms in all patients at completion of this therapy. Lesions that involved the hard palate and vocal cords had completely disappeared. The lesions that received radiotherapy were controlled without symptoms until the patients died. Patients who had the head and neck region treated exhibited severe acute mucosal reaction (at a dose of 30 Gy, there was grade 2 morbidity by modified RTOG criteria, in two patients, and grade 3 in three patients) although the radiation therapy was completed for these patients. Radiotherapy promises a favorable outcome for symptom relief in AIDS-related Kaposi's sarcoma. (author)

  4. Detection of the sarin hydrolysis product in formalin-fixed brain tissues of victims of the Tokyo subway terrorist attack.

    Science.gov (United States)

    Matsuda, Y; Nagao, M; Takatori, T; Niijima, H; Nakajima, M; Iwase, H; Kobayashi, M; Iwadate, K

    1998-06-01

    One of the hydrolysis products of sarin (isopropyl methylphosphonofluoridate) was detected in formalin-fixed brain tissues of victims poisoned in the Tokyo subway terrorist attack. Part of this procedure, used for the detection of sarin hydrolysis products in erythrocytes of sarin victims, has been described previously. The test materials were four individual cerebellums, which had been stored in formalin fixative for about 2 years. Sarin-bound acetylcholinesterase (AChE) was solubilized from these cerebellums, purified by immunoaffinity chromatography, and digested with trypsin. Then the sarin hydrolysis products bound to AChE were released by alkaline phosphatase digestion, subjected to trimethylsilyl derivatization (TMS), and detected by gas chromatography-mass spectrometry. Peaks at m/z 225 and m/z 240, which are indicative of TMS-methylphosphonic acid, were observed within the retention time range of authentic methylphosphonic acid. However, no isopropyl methylphosphonic acid was detected in the formalin-fixed cerebellums of these 4 sarin victims, probably because the isopropoxy group of isopropyl methylphosphonic acid underwent chemical hydrolysis during storage. This procedure will be useful for the forensic diagnosis of poisoning by protein-bound, highly toxic agents, such as sarin, which are easily hydrolysed. This appears to be the first time that intoxication by a nerve agent has been demonstrated by analyzing formalin-fixed brains obtained at autopsy.

  5. A decade after the Tokyo sarin attack: a review of neurological follow-up of the victims.

    Science.gov (United States)

    Hoffman, Azik; Eisenkraft, Arik; Finkelstein, Arseny; Schein, Ophir; Rotman, Eran; Dushnitsky, Tsvika

    2007-06-01

    On March 20, 1995, sarin gas was used in Tokyo by members of the Japanese "Uhm-Shinrikiu" cult, killing 12 and injuring >5,500 innocent people. Most of the casualties were mildly injured. This article reviews the neurological follow-up data for some of the victims over the past decade. We reviewed the published literature regarding neurological follow-up of the victims, dividing the data according to the time elapsed after the attack. The digit span test, finger-tapping test, and computerized posturography were the only performance tests that showed statistically significant differences between the victims and the control groups in some of the surveys. The main sequela 7 years after the attack was post-traumatic stress disorder. The results emphasize the need for a national preparedness program for such mass casualty events, led by national health systems. This should include long-term, neurological, follow-up monitoring with performance tests and a post-traumatic stress disorder screening test.

  6. Biting Density and Distribution of Aedes albopictus during the September 2014 Outbreak of Dengue Fever in Yoyogi Park and the Vicinity of Tokyo Metropolis, Japan.

    Science.gov (United States)

    Tsuda, Yoshio; Maekawa, Yoshihide; Ogawa, Kohei; Itokawa, Kentaro; Komagata, Osamu; Sasaki, Toshinori; Isawa, Haruhiko; Tomita, Takashi; Sawabe, Kyoko

    2016-01-01

    A total of 160 autochthonous dengue cases transmitted by Aedes albopictus were reported between August and October of 2014 in Tokyo Metropolis, Japan. Ae. albopictus is a medically important vector of dengue virus, which has expanded its geographic distribution in temperate regions. Understanding the distribution and biting density of Ae. albopictus during the 2014 dengue outbreak in Tokyo is important to evaluate the epidemic risks of dengue fever in other highly populated cities in Europe and Asia. Of the 160 patients, 134 visited the same park (Yoyogi Park) located in central Tokyo. Mosquitoes infected with dengue virus were collected from this park, suggesting that it was the exclusive location for the transmission of dengue. This study aimed to collect referential data to estimate the transmission threshold of dengue virus in terms of biting density of Ae. albopictus and determined high transmission risk areas of dengue virus in Yoyogi Park and its vicinity. The overall mean density of biting Ae. albopictus (7.13/man/8 min) was sufficiently high for successful transmission of dengue virus, and areas with biting densities higher than the overall mean density were classified as high risk areas for the transmission of dengue virus in Yoyogi Park.

  7. Deep sequencing analysis of the heterogeneity of seed and commercial lots of the bacillus Calmette-Guérin (BCG) tuberculosis vaccine substrain Tokyo-172

    Science.gov (United States)

    Wada, Takayuki; Maruyama, Fumito; Iwamoto, Tomotada; Maeda, Shinji; Yamamoto, Taro; Nakagawa, Ichiro; Yamamoto, Saburo; Ohara, Naoya

    2015-01-01

    BCG, only vaccine available to prevent tuberculosis, was established in the early 20th century by prolonged passaging of a virulent clinical strain of Mycobacterium bovis. BCG Tokyo-172, originally distributed within Japan in 1924, is one of the currently used reference substrains for the vaccine. Recently, this substrain was reported to contain two spontaneously arising, heterogeneous subpopulations (Types I and II). The proportions of the subpopulations changed over time in both distributed seed lots and commercial lots. To maintain the homogeneity of live vaccines, such variations and subpopulational mutations in lots should be restrained and monitored. We incorporated deep sequencing techniques to validate such heterogeneity in lots of the BCG Tokyo-172 substrain without cloning. By bioinformatics analysis, we not only detected the two subpopulations but also detected two intrinsic variations within these populations. The intrinsic variants could be isolated from respective lots as colonies cultured on plate media, suggesting analyses incorporating deep sequencing techniques are powerful, valid tools to detect mutations in live bacterial vaccine lots. Our data showed that spontaneous mutations in BCG vaccines could be easily monitored by deep sequencing without direct isolation of variants, revealing the complex heterogeneity of BCG Tokyo-172 and its daughter lots currently in use. PMID:26635118

  8. What Triggers a Diagnosis of HIV Infection in the Tokyo Metropolitan Area? Implications for Preventing the Spread of HIV Infection in Japan.

    Science.gov (United States)

    Nishijima, Takeshi; Takano, Misao; Matsumoto, Shoko; Koyama, Miki; Sugino, Yuko; Ogane, Miwa; Ikeda, Kazuko; Kikuchi, Yoshimi; Oka, Shinichi; Gatanaga, Hiroyuki

    2015-01-01

    Japan has not succeeded in reducing the annual number of new HIV-infected patients, although the prevalence of HIV infection is low (0.02%). A single-center observational study was conducted at the largest HIV clinic in Tokyo, which treats 15% of the total patients in Japan, to determine the reasons for having diagnostic tests in newly infected individuals. HIV-infected patients who visited our clinic for the first time between 2011 and 2014 were analyzed. The 598 study patients comprised one-third of the total reported number of new patients in Tokyo during the study period. 76% were Japanese MSM. The reasons for being tested which led to the diagnosis was voluntary testing in 32%, existing diseases in 53% (AIDS-defining diseases in 22%, sexually transmitted infections (STI) in 8%, diseases other than AIDS or STIs in 23%) and routine pre-surgery or on admission screening in 15%. 52% and 74% of the study patients and patients presented with AIDS, respectively, had never been tested. The median CD4 count in patients with history of previous testing (315/μL) was significantly higher than that of patients who had never been tested (203/μL, pTokyo metropolitan area.

  9. Measurement of radioactivity in airborne dust and estimation of public dose in Tokyo after the Fukushima Daiichi Nuclear Power Plant accident

    International Nuclear Information System (INIS)

    Nagakawa, Yoshiyasu; Suzuki, Takashi; Kinjo, Yasuhito; Sakurai, Noboru; Sotodate, Takahiro; Ise, Hiroaki

    2013-01-01

    We report on the results of emergency monitoring of environmental radiation in Tokyo after the severe accident at the Fukushima Daiichi Nuclear Power Plant, triggered by the Great East Japan Earthquake and the resulting tsunami on the 11th March 2011. We collected airborne dust samples at the Setagaya and Koto districts of Tokyo. The concentrations of radionuclides were measured by a Ge semiconductor detector. The highest concentrations of major fission products were detected at 10:00-11:00 a.m. on the 15th March 2011. The detected concentrations were: 2.4×10 2 Bq/m 3 of 131 I, 6.4×10 1 Bq/m 3 of 134 Cs, and 6.0×10 1 Bq/m 3 of 137 Cs. The concentration of 131 I fell to undetectable levels by June 2011. In contrast, 134 Cs and 137 Cs were detected intermittently for one year. Based on the results on the concentrations of detected nuclides, the public internal doses due to inhalation were estimated on the assumption that those in the affected area stayed outdoors continuously for the period from the 13th March 2011 to the 12th March 2012 in the Tokyo metropolitan area. The committed effective dose due to inhalation for adults was estimated to be 25 μSv. (author)

  10. Influence of the Tohoku-Pacific Ocean earthquake and its aftershocks on the response to prophylactic therapy with lomerizine in patients with migraine in Tokyo: a retrospective study.

    Science.gov (United States)

    Ishii, Masakazu; Katoh, Hirotaka; Takagi, Maho; Kawamura, Mitsuru; Shimizu, Shunichi

    2014-01-01

    On March 11, 2011, the Tohoku-Pacific Ocean earthquake (magnitude 9.0) struck the eastern part of Japan. Despite being far from the epicenter of the catastrophic earthquake, the effects were strongly felt in Tokyo, and the aftershocks continued for several months. There are no reports regarding the influence of earthquakes on migraine medication. The aim of our study was to determine the impact of earthquakes on prophylactic therapy with lomerizine in patients with migraine in Tokyo. The study included patients with migraine who were admitted to outpatient clinics in Tokyo between January 2010 and July 2010 or between January 2011 and July 2011 and who were prescribed lomerizine prophylactically for headache by specialists. We investigated clinical factors from the medical records for 26 of these patients. The study population included 10 patients in 2010 and 16 patients in 2011. The frequency of headaches was reduced to under 5 days/month during February in both the groups. Compared to 2010, the frequency of headaches significantly increased in 2011 in March, April and May. Patients with migraine were sensitive to exposure to the earthquake and their headaches worsened despite successful prophylactic treatment with lomerizine before the Tohoku-Pacific Ocean earthquake. © 2014 S. Karger AG, Basel.

  11. PREFACE: Proceedings of the 2nd International Conference on Quantum Simulators and Design (Tokyo, Japan, 31 May-3 June 2008) Proceedings of the 2nd International Conference on Quantum Simulators and Design (Tokyo, Japan, 31 May-3 June 2008)

    Science.gov (United States)

    Akai, Hisazumi; Tsuneyuki, Shinji

    2009-02-01

    This special issue of Journal of Physics: Condensed Matter comprises selected papers from the proceedings of the 2nd International Conference on Quantum Simulators and Design (QSD2008) held in Tokyo, Japan, between 31 May and 3 June 2008. This conference was organized under the auspices of the Development of New Quantum Simulators and Quantum Design Grant-in-Aid for Scientific Research on Priority Areas, Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT). The conference focused on the development of first principles electronic structure calculations and their applications. The aim was to provide an opportunity for discussion on the progress in computational materials design and, in particular, the development of quantum simulators and quantum design. Computational materials design is a computational approach to the development of new materials. The essential ingredient is the use of quantum simulators to design a material that meets a given specification of properties and functionalities. For this to be successful, the quantum simulator should be very reliable and be applicable to systems of realistic size. During the conference, new methods of quantum simulation and quantum design were discussed including methods beyond the local density approximation of density functional theory, order-N methods, methods dealing with excitations and reactions, and the application of these methods to the design of novel materials, devices and systems. The conference provided an international forum for experimental and theoretical researchers to exchange ideas. A total of 220 delegates from eight countries participated in the conference. There were 13 invited talks, ten oral presentations and 120 posters. The 3rd International Conference on Quantum Simulators and Design will be held in Germany in the autumn of 2011.

  12. Nueva mutación heterocigota en el gen de la proteína regulatoria aguda de la esteroideogénesis (StAR en un paciente 46,XY con hiperplasia adrenal congénita lipoidea

    Directory of Open Access Journals (Sweden)

    María Sonia Baquedano

    2013-08-01

    Full Text Available StAR forma parte del complejo multiproteico transduceosoma, encargado del transporte de colesterol y que facilita su entrada a la mitocondria. Mutaciones recesivas en el gen STAR causan formas clásicas y no clásicas de hiperplasia adrenal congénita lipoidea. Analizamos las consecuencias moleculares de una nueva mutación heterocigota en STAR en un paciente 46,XY con genitales ambiguos e insuficiencia adrenal. Hallamos un cambio heterocigota de novo, IVS1-2A>G, en el gen STAR y el polimorfismo heterocigota, pG146A, en SF1. No se detectaron mutaciones en los genes CYP11A1, FDX1 y FDXR, VDAC1 y TSPO. Por RT-PCR y secuenciación se observó un transcripto-exón2 y el transcripto normal (WT de StAR, a partir del ARN de tejido gonadal del paciente. Se detectó el precursor (37 kD y la proteína StAR madura (30 kD en células COS-7 transfectadas con el plásmido mutante y WT. Por inmunofluorescencia la observación de co-localización de la proteína mutante (p.G22_L59delStAR en mitocondrias fue casi nula. La actividad de p.G22_L59delStAR fue del 65% ± 13 respecto del WT. La co-transfección de los plásmidos p.G22_L59delStAR y WT redujo la actividad de WT en 62.0 ± 13.9%. La mutación IVS1-2A>G provocó la pérdida de los aminoácidos 22 a 59 en la secuencia mitocondrial N-terminal. Postulamos que ello conduciría a un plegamiento anormal de la proteína que alteraría su procesamiento y translocación. La proteína mutante p.G22_L59delStAR podría interferir con la acción de la proteína StAR WT bloqueando el complejo transduceosoma y causando una forma dominante de deficiencia de StAR, que explicaría el fenotipo clínico en heterocigosis.

  13. Correlación hemodinámica, anatomopatológica y posquirúrgica en las cardiopatías congénitas con hipertensión pulmonar

    Directory of Open Access Journals (Sweden)

    Herminia Palenzuela López

    1995-04-01

    Full Text Available Se revisan los resultados del estudio hemodinámico y los hallazgos anatomopatológicos cualitativos y cuantitativos, así como su correspondencia entre sí y con la evolución posoperatoria, en 20 pacientes con cardiopatía congénita e hipertensión pulmonar. Se encontraron respuestas favorables a la prueba con vasodilatadores en más del 70 % de los casos, no siempre en relación con la severidad de las lesiones anatomopatológicas. Se hallaron cifras del índice de grosor de la capa media mayores del 20 % en la mayoría de los casos, y predominaron los valores menores del 25 % en los casos con lesiones de Heath y Edwards mayor de II. Se demostró relación estadísticamente significativa entre los valores del índice de grosor de la capa media más elevados y la edad media menor, así como entre el grado de reducción de las resistencias vasculares pulmonares con vasodilatadores y los valores menores del índice de grosor de la capa media. Predominaron las lesiones de tipo II de Heath y Edwards a pesar de la edad quirúrgica algo tardía de algunos casos. Los fallecidos por hipertensión pulmonar estuvieron entre los casos con lesiones de tipo II de Heath y Edwards e índice de grosor de la capa media mayores del 25 %. La evolución de la hipertensión pulmonar en general fue más favorable de lo esperado. Se concluye que ninguna prueba por sí sola permite predecir operabilidad, por lo que será necesario profundizar en el estudio anatomopatológico cuantitativo en los casos dudosos como un medio más para una decisión más correcta.

  14. Lifestyle constraints, not inadequate nutrition education, cause gap between breakfast ideals and realities among Japanese in Tokyo.

    Science.gov (United States)

    Melby, Melissa K; Takeda, Wakako

    2014-01-01

    Japanese public health nutrition often promotes 'traditional' cuisine. In-depth interviews with 107 Japanese adults were conducted in Tokyo from 2009 to 2011, using free-listing methods to examine dietary ideals and realities to assess the extent to which realities reflect inadequate nutrition education or lifestyle constraints. Ideal-reality gaps were widest for breakfast. Most people reported Japanese ideals: rice and miso soup were prototypical foods. However, breakfast realities were predominantly western (bread-based). While those aged 40-59 were more likely to hold Japanese ideals (P=0.063), they were less likely to achieve them (P=0.007). All those reporting western ideals achieved them on weekdays, while only 64% of those with Japanese ideals achieved them (PJapanese ideals were positively correlated with proportion of cooking-related housework, and negatively correlated with living standard and income. Ideal menu content was in line with current Japanese nutrition advice, suggesting that more nutrition education may not change dietary ideals or behavior. Participant-reported reasons for ideal-reality discordance demonstrate that work-life balance issues, especially lack of time and family structure/life rhythm, are the largest obstacles to the attainment of dietary ideals. People reporting 'no time' as a primary reason for ideal-reality gaps were less likely to achieve their Japanese ideals (odds ratio=0.212). Time realities of people's lives may undermine educational efforts promoting Japanese breakfasts. When dietary reality/behavior departs from guidelines, it is often assumed that people lack knowledge. If ideals are in line with dietary guidelines, then lack of knowledge is not the likely cause and nutrition education is not the optimal solution. By asking people about the reasons for gaps between their ideals and realities, we can identify barriers and design more effective policies and programs to achieve dietary ideals. Copyright © 2013 Elsevier

  15. Immunocytochemical survey of the neuroepithelial endocrine system in the respiratory tract of the Tokyo salamander, Hynobius nebulosus tokyoensis TAgo.

    Science.gov (United States)

    Gomi, T; Kikuchi, Y; Adriaensen, D; Timmermans, J P; De Groodt-Lasseel, M H; Kimura, A; Naruse, H; Ishikawa, Y; Kishi, K; Scheuermann, D W

    1994-12-01

    The epithelial lining of the respiratory tract of urodeles has been shown to harbor an innervated system of neuroepithelial endocrine (NEE) cells. Even between phylogenetically closely related species, large differences have been reported in the appearance and chemical coding of the NEE system. Although urodeles are well suited for the purpose, none of the prior studies have provided an immunocytochemical survey of the NEE system in all parts of the respiratory tract. In the present study, many bioactive substances and a general marker were immunocytochemically demonstrated in serial sections of the entire respiratory tract of the Tokyo salamander, Hynobius nebulosus tokyoensis, a species in which neuroepithelial bodies (NEBs) were previously characterized at the electron microscopic level. In the current study, serotonin-immunoreactive solitary NEE cells were observed in variable numbers in the larynx, in all parts of the trachea, and in areas of the lungs covered with ciliomucous epithelium. Serotonin-containing NEBs, however, were detected in small cranial areas of the lung only. Solitary NEE cells were seen in the trachea and lungs of H. nebulosus tokyoensis by immunocytochemical staining for somatostatin, calcitonin, calcitonin gene-related peptide, and bombesin, but the number, localization, and appearance of the labeled NEE cells differed considerably. Only calcitonin-like immunoreactivity was also noted in some NEB-like cell clusters in the cranial parts of the lungs. Unlike many other vertebrates, neuron specific enolase was found to be a poor marker for the NEE system in the salamander species used in this investigation. It may be concluded that the NEE system of H. nebulosus tokyoensis contains at least five different bioactive substances.(ABSTRACT TRUNCATED AT 250 WORDS)

  16. Detection of Norovirus in Swab Specimens of Restrooms and Kitchens Collected for Investigation of Suspected Food Poisoning Outbreaks in Tokyo.

    Science.gov (United States)

    Somura, Yoshiko; Kimoto, Kana; Oda, Mayuko; Nagano, Miyuki; Okutsu, Yuta; Mori, Kohji; Akiba, Tetsuya; Sadamasu, Kenji

    2017-01-01

    During 2015-2016, we examined norovirus (NoV) RNA in swab specimens collected for investigation of suspected food poisoning outbreaks in Tokyo by real-time RT-PCR. Of 1,726 swab samples, 65 (3.8%) were NoV-positive and all positive swab samples were derived from NoV-positive outbreaks. Swab specimens were positive in 41 of 181 (22.7%) NoV outbreaks, while no positive swabs were detected in NoV-negative outbreaks. PCR fragments amplified from 32 swabs were sequenced, and all of them displayed complete homology with sequences from clinical and food samples. Though the results of swabs may be useful for determining the causative agent and infection route in some outbreaks, there was no case in which the results of swabs alone could elucidate the cause of food poisoning. Swabs may be useful in food poisoning investigations, if the results are interpreted in conjunction with epidemiological findings and clinical data. Swab samples are often collected several days after an outbreak, and the influence of disinfection should be taken into consideration. In NoV outbreaks, 55 out of 640 (8.6%) restroom swab specimens were NoV-positive whereas six of 618 (1.0%) were positive among kitchen swab specimens. In the restroom, the toilet bowl (43.6%) showed the highest positive rate and next was the toilet seat (14.5%). Additionally, NoV was detected at various sites in the restroom, including doorknob and floor. Since NoV-positive swab specimens may suggest that sanitation management is not performed properly in the facility, swab results may be utilized as a basis for hygiene guidance.

  17. Detection of Enteric Viruses in Fecal Specimens from Nonbacterial Foodborne Gastroenteritis Outbreaks in Tokyo, Japan between 1966 and 1983.

    Science.gov (United States)

    Mori, Kohji; Nagano, Miyuki; Kimoto, Kana; Somura, Yoshiko; Akiba, Tetsuya; Hayashi, Yukinao; Sadamasu, Kenji; Kai, Akemi

    2017-03-24

    We investigated the prevalence of 5 enteric viruses (norovirus [NoV], sapovirus, rotavirus, astrovirus, and adenovirus) in archived stool specimens collected from 70 foodborne gastroenteritis outbreaks in Tokyo, Japan, which occurred from 1966 to 1983, and genetically characterized these viruses. NoV was detected in 48 (68.6%) outbreaks, while SaV, group C rotavirus (RVC), and astrovirus were detected in 1 (1.4%) outbreak each. Based on the partial capsid sequences, the detected NoVs were classified into the following genotypes: 9 in genogroup I (GI; GI.1-6, GI.8, GI.9, and GI.NA), 13 GII (GII.1-9, GII.13, GII.16, GII.17, and GII.22), and one in GIV. The oldest NoV outbreaks occurred in 1966. No predominant genotype was found. One strain, classified as GI. NA based on the N/S region sequence, was subsequently classified as GI.8 based on the complete VP1 sequence. Nine types of recombinant NoV sequences, including 7 unreported combinations, were identified. Further genetic characterization of NoV GII.17 and GII.4 demonstrated that the NoV GII.17 strains detected from 1970 to 1982 clustered independently from previously reported NoV GII.17 strains. Phylogenetic analysis, using the complete VP1 region and the P2 domain, demonstrated that NoV GII.4 strains collected between 1975 and 1980 clustered with archival strains collected in the USA in the mid-1970s. In contrast, a NoV GII.4 strain collected in 1983 formed an independent branch from reference strains collected in the mid-1970s to 2012.

  18. Acute exposure to fine and coarse particulate matter and infant mortality in Tokyo, Japan (2002-2013).

    Science.gov (United States)

    Yorifuji, Takashi; Kashima, Saori; Doi, Hiroyuki

    2016-05-01

    Few studies have evaluated the effect of short-term exposure to particulate matter (PM) less than 2.5μm in diameter (PM2.5) or to coarse particles on infant mortality. We evaluated the association between short-term exposure to PM and infant mortality in Japan and assessed whether adverse health effects were observable at PM concentrations below Japanese air quality guidelines. We used a time-stratified, case-crossover design. The participants included 2086 infants who died in the 23 urbanized wards of the Tokyo Metropolitan Government between January 2002 and December 2013. We obtained measures of PM2.5 and suspended particulate matter (SPM; PM<7μm in diameter) from one general monitoring station. As a measure of coarse particles, we calculated PM7-2.5 by subtracting PM2.5 from SPM. We then used conditional logistic regression to analyze the data. Same-day PM2.5 was associated with increased risks of infant and postneonatal mortality, especially for mortality related to respiratory causes. For a 10μg/m(3) increase in PM2.5, the odds ratios were 1.06 (95% confidence interval: 1.01-1.12) for infant mortality and 1.10 (1.02-1.19) for postneonatal mortality. PM7-2.5 was also associated with an increased risk of postneonatal mortality, independent of PM2.5. Even when PM2.5 and SPM concentrations were below Japanese air quality guidelines, we observed adverse health effects. This study provides further evidence that acute exposure to PM2.5 and coarse particles (PM7-2.5) is associated with an increased risk of infant mortality. Further, rigorous evaluation of air quality guidelines for daily average PM2.5 and larger particles is needed. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Physiological and Growth Characteristics of Brassica rapa 'Tokyo Bekana' Grown within the International Space Station Crop Production System

    Science.gov (United States)

    Burgner, Samuel Edward

    The National Aeronautics and Space Administration (NASA) as well as many other space research organizations across the globe have advanced the idea of using plants as a method of bioregenerative life support for decades. Currently, the International Space Station (ISS) houses a small vegetable-production system named "Veggie." Veggie is equipped with a light-emitting diode (LED) cap, a reservoir that provides water to the root zone through capillary action, and adjustable bellows that enclose the growing environment allowing for controlled air circulation. However, Veggie draws air from the cabin space and ISS environmental conditions are controlled for human comfort and function as opposed to optimal plant growth conditions. During the first experiment within Veggie aboard the ISS, temperature averaged 22 ºC (+/- 0.25), relative humidity was 43.9% (+/- 3.7), and CO2 fluctuated around 2,800 ppm (+/- 678). Preliminary trials selected Chinese cabbage (Brassica rapa 'Tokyo Bekana') as the most suitable cultivar for production within Veggie based on its horticultural, organoleptic, and nutritional characteristics. Introducing this cultivar into ISS conditions (mimicked in a growth chamber) led to extensive chlorosis, necrosis, and growth inhibition. Attempts to ameliorate this observed stress by changing light spectrum, slow-release fertilizer composition, and growth substrate were unsuccessful suggesting that this issue could be attributed to environmental conditions. Analyzing effects of CO2 at 450, 900 and 1350 ppm on growth, photosynthesis, and stomatal conductance in this cultivar revealed a poor ability to acclimate to this environmental variable. In order to develop an efficient system of plant production aboard the ISS or other potential spacecraft, a more efficient CO2 regulation system must be implemented within the cabin space or within a defined plant production area and species should be screened based on their ability to thrive in such an environment.

  20. A retrospective histopathological survey on canine and feline liver diseases at the University of Tokyo between 2006 and 2012.

    Science.gov (United States)

    Hirose, Naoki; Uchida, Kazuyuki; Kanemoto, Hideyuki; Ohno, Koichi; Chambers, James K; Nakayama, Hiroyuki

    2014-07-01

    To determine the incidence of hepatic diseases in dogs and cats in Japan, a retrospective study was performed using data of 463 canine and 71 feline liver biopsies at the Veterinary Medical Center of the University of Tokyo. The most common canine hepatic disease was microvascular dysplasia (MVD) and occupied 29.4% of all diagnoses. This terminology might contain "real" MVD and primary portal vein hypoplasia, because these two conditions were difficult to be clearly distinguished histopathologically. Parenchymal and interstitial hepatitis and primary hepatic tumors accounted for 23.5% and 21.0% of the diagnoses, respectively. Parenchymal and interstitial hepatitis occupied 34.1% of non-proliferative canine hepatic diseases, while hepatocellular adenoma and carcinoma were 26.6% and 24.5% of proliferative hepatic diseases, respectively. Breed-specificity was seen in MVD for Yorkshire terrier, Papillon and Toy poodle, in hepatitis for Doberman pinscher and Labrador retriever, in cholangiohepatitis for American cocker spaniel, Miniature schnauzer and Pomeranian, in hepatocellular adenoma for Golden retriever and Shiba and in hepatocellular carcinoma for Shih Tzu. The most common feline liver disease was parenchymal and interstitial hepatitis (45.1% of all diagnoses). Among feline hepatitis, neutrophilic cholangiohepatitis (23.9%), lymphocytic cholangiohepatitis (14.1%) and chronic hepatitis (5.6%) were recorded. Adult polycystic liver disease was 5.6%. Among proliferative diseases in the feline liver (11.3% of the all), lymphoma (4.2%) and primary epithelial tumors (4.2%) including hepatocellular carcinoma, cholangiocellular adenoma and cholangiocellular carcinoma were observed. Hepatic degeneration was 14.1%, and MVD was 12.7%, respectively.

  1. Long term effects of exposure to automobile exhaust on the pulmonary function of female adults in Tokyo, Japan

    Science.gov (United States)

    Sekine, K; Shima, M; Nitta, Y; Adachi, M

    2004-01-01

    Aims: To investigate the chronic effects of air pollution caused mainly by automobiles in healthy adult females. Methods: Respiratory symptoms were investigated in 5682 adult females who had lived in the Tokyo metropolitan area for three years or more in 1987; 733 of them were subjected to pulmonary function tests over eight years from 1987 to 1994. The subjects were divided into three groups by the level of air pollution they were exposed to during the study period. The concentrations of nitrogen dioxide and suspended particulate matter were the highest in group 1, and the lowest in group 3. Results: The prevalence rates of respiratory symptoms in group 1 were higher than those in groups 2 and 3, except for wheezing. Multiple logistic regression analysis showed significant differences in persistent phlegm and breathlessness. The subjects selected for the analysis of pulmonary function were 94, 210, and 102 females in groups 1, 2, and 3, respectively. The annual mean change of FEV1 in group 1 was the largest (-0.020 l/y), followed by that in group 2 (-0.015 l/y), and that in group 3 (-0.009 l/y). Testing for trends showed a significant larger decrease of FEV1 with the increase in the level of air pollution. Conclusions: The subjects living in areas with high levels of air pollution showed higher prevalence rates of respiratory symptoms and a larger decrease of FEV1 compared with those living in areas with low levels of air pollution. Since the traffic density is larger in areas with high air pollution, the differences among the groups may reflect the effect of air pollution attributable to particulate matter found in automobile exhaust. PMID:15031394

  2. Situations of decontamination promotion activities. Efforts by Tokyo Electric Power Company, Fukushima Revitalization Headquarters, Decontamination Promotion Office

    International Nuclear Information System (INIS)

    Takano, Takahiko; Ito, Kei; Takizawa, Koichi

    2015-01-01

    As for the decontamination of the soil contaminated with radioactive materials, decontamination is on the way in compliance with the 'Act on Special Measures Concerning the Handling of Environmental Pollution by Radioactive Materials by the NPS Accident Associated with the Tohoku District - Off the Pacific Ocean' (hereinafter, the Act on Special Measures). Tokyo Electric Power Company (TEPCO), as the party concerned to the accident, is cooperating with decontamination activities conducted by countries and municipalities under the Act on Special Measures. Total number of people cooperated by the Decontamination Promotion Office amounts to about 120,000 people. The cooperation to the decontamination by countries and municipalities covers the following fields: provision of knowledge of radiation, training of site management and supervisors, and proposal such as the decontamination method suitable for the site. As cooperation to various monitoring, there is a traveling monitoring that performs radiation measurement from the vehicles. As cooperation in the farming and industrial resumption toward the reconstruction, the group has implemented support for the distribution promotion of the holdup that was stuck in distribution due to contamination with radioactive substances. As decontamination related technology, the following are performed: (1) preparation of radiation understanding promotion tool, (2) development of precise individual dose measurement technology, and (3) development and utilization of decontamination effect analysis program. In the future, this group will perform the follow-up for decontamination, and measures toward the lifting of evacuation order. It will install the basis to perform various technical analyses on decontamination, and will further intensify technical cooperation. (A.O.)

  3. Polychlorinated dioxins, furans, and biphenyls in blood of children and adults living in a dioxin-contaminated area in Tokyo.

    Science.gov (United States)

    Tohyama, Chiharu; Uchiyama, Iwao; Hoshi, Shuji; Hijiya, Masaki; Miyata, Hideaki; Nagai, Masaki; Nakai, Satoshi; Yauchi, Mariko; Ohkubo, Satsuki

    2011-01-01

    The soil of a residential area in Tokyo was found to contain dioxins, namely polychlorinated dioxins, furans, and dioxin-like biphenyls, the levels of which exceeded the environmental guideline [1,000 pg toxic equivalent (TEQ)/g] by up to 6.8 times. To assess the exposure levels of people living in this area and to study the possible relationship of blood dioxin concentrations of children with breast milk and/or formula feeding, a health survey was carried out in 2006, involving a total of 138 people, including 66 children aged 3-15 years, and blood dioxin concentrations and the characteristics and lifestyles of these people were analyzed. Mean ± standard error of the mean (SEM) of blood dioxin concentrations (pg/g-lipid) of group 1 (3-6 years old), group 2 (7-15 years old), and group 3 (≥16 years old) were 13 ± 1.9, 6.6 ± 0.65, and 10 ± 0.54, respectively. The congener/isomer profile of dioxins in blood samples differed markedly from that of the contaminated soil samples. According to the feeding mode of children, blood dioxin concentrations (pg/g-lipid) were 17 ± 2.9 for breast milk only, 7.4 ± 0.82 for both breast milk and formula, and 4.7 ± 1.1 for formula only, with a significant difference from one another. We conclude that people living in the dioxin-contaminated area are less likely to be exposed to excessive amounts of dioxins, and that blood dioxin concentrations of children aged 3-15 years seem to be strongly affected by breast feeding duration.

  4. Factors and values at admission that predict a fulminant course of acute myocarditis: data from Tokyo CCU network database.

    Science.gov (United States)

    Inaba, Osamu; Satoh, Yasuhiro; Isobe, Mitsuaki; Yamamoto, Takeshi; Nagao, Ken; Takayama, Morimasa

    2017-08-01

    Prognosis of acute myocarditis is generally benign, but fulminant cases exist which require advanced life support devices, such as percutaneous cardio-pulmonary support (PCPS) and ventricular assist devices (VAD), and lead to fatal outcomes. The purpose of this study was to identify predictors and their values at admission which might foreshadow a fulminant course of myocarditis. Data from 138 patients (mean age 42.0 years, 79 males) with a diagnosis of acute myocarditis in the Tokyo CCU Network database from 2007 to 2009 were analyzed retrospectively. Patients were divided into fulminant (in-hospital death, or PCPS or VAD requirement, N = 42) and non-fulminant groups (N = 96). Clinical data at admission were compared between them. Overall in-hospital mortality was 14.5%. On multivariate analysis, low systolic blood pressure (BPsys, odds ratio (OR)/mmHg 0.97; 95% confidence interval (CI) 0.93-1.00, p = 0.032) and electrocardiographic QRS complex prolongation (OR/10 ms 1.28; 95% CI 1.10-1.59, p = 0.0034) at admission were independent factors associated with a fulminant course. By receiver operator characteristic curve analysis, the area under the curve predicting a fulminant course was 0.769 for low BPsys and 0.821 for prolongation of QRS duration. The optimal cut-off value was 101 mmHg for BPsys (sensitivity 79.5%, specificity 68.0%), and 120 ms for QRS duration (sensitivity 72.2%, specificity 88.0%). Systolic hypotension and prolonged QRS on admission are predictors of a fulminant course of myocarditis.

  5. Relationship between the Prediction Accuracy of Tsunami Inundation and Relative Distribution of Tsunami Source and Observation Arrays: A Case Study in Tokyo Bay

    Science.gov (United States)

    Takagawa, T.

    2017-12-01

    A rapid and precise tsunami forecast based on offshore monitoring is getting attention to reduce human losses due to devastating tsunami inundation. We developed a forecast method based on the combination of hierarchical Bayesian inversion with pre-computed database and rapid post-computing of tsunami inundation. The method was applied to Tokyo bay to evaluate the efficiency of observation arrays against three tsunamigenic earthquakes. One is a scenario earthquake at Nankai trough and the other two are historic ones of Genroku in 1703 and Enpo in 1677. In general, rich observation array near the tsunami source has an advantage in both accuracy and rapidness of tsunami forecast. To examine the effect of observation time length we used four types of data with the lengths of 5, 10, 20 and 45 minutes after the earthquake occurrences. Prediction accuracy of tsunami inundation was evaluated by the simulated tsunami inundation areas around Tokyo bay due to target earthquakes. The shortest time length of accurate prediction varied with target earthquakes. Here, accurate prediction means the simulated values fall within the 95% credible intervals of prediction. In Enpo earthquake case, 5-minutes observation is enough for accurate prediction for Tokyo bay, but 10-minutes and 45-minutes are needed in the case of Nankai trough and Genroku, respectively. The difference of the shortest time length for accurate prediction shows the strong relationship with the relative distance from the tsunami source and observation arrays. In the Enpo case, offshore tsunami observation points are densely distributed even in the source region. So, accurate prediction can be rapidly achieved within 5 minutes. This precise prediction is useful for early warnings. Even in the worst case of Genroku, where less observation points are available near the source, accurate prediction can be obtained within 45 minutes. This information can be useful to figure out the outline of the hazard in an early

  6. Current status of the use of inferior vena cava filters in cases of pulmonary embolism in CCUs: From the Tokyo CCU Network.

    Science.gov (United States)

    Tanabe, Yasuhiro; Obayashi, Toru; Yamamoto, Takeshi; Nakata, Jun; Yagi, Hidenori; Takayama, Morimasa; Nagao, Ken

    2014-05-01

    To elucidate the current status of use of inferior vena cava filters (IVCFs) in cases of pulmonary embolism at institutions belonging to the Tokyo CCU Network. We conducted a retrospective investigation of 832 consecutive cases of pulmonary embolism reported on survey forms to the Tokyo CCU Network between 2005 and 2010. Of 832 cases of pulmonary embolism, IVCFs were used in 338 (40.6%) and not used in 415 (49.9%). Their use was unclear in 79 (9.5%) cases. The use rate gradually increased each year from 2005 until 2008 but decreased from 2009 onward. Moreover, 68.9% of the IVCFs used in cases were non-permanent types. In terms of pulmonary embolism severity, the rate of use was 37.2% in non-massive cases, 49.4% in sub-massive cases, 46.9% in massive cases, and 31.9% in collapse cases. Thirty-day mortality in cases of collapse in which IVCFs were not used was extremely high at 75.8%, suggesting that in many cases, rapid deterioration may occur with insufficient time for IVCF insertion. The differences in IVCF usage rate among institutions were large in the range of 12.5-90% from 2005 to 2008, which slightly declined to the range of 25.0-72.2% from 2009 to 2010. We elucidated the current IVCF use status in cases of pulmonary embolism at institutions belonging to the Tokyo CCU Network. Since the status of use differed among institutions, future studies of effective methods of use are required. Copyright © 2013 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  7. Temporal trends for inflow of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) to Tokyo Bay, Japan, estimated by a receptor-oriented approach.

    Science.gov (United States)

    Sakurai, Takeo; Serizawa, Shigeko; Kobayashi, Jun; Kodama, Keita; Lee, Jeong-Hoon; Maki, Hideaki; Zushi, Yasuyuki; Sevilla-Nastor, Janice Beltran; Imaizumi, Yoshitaka; Suzuki, Noriyuki; Horiguchi, Toshihiro; Shiraishi, Hiroaki

    2016-01-01

    We estimated inflow rates of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) to Tokyo Bay, Japan, between February 2004 and February 2011 by a receptor-oriented approach based on quarterly samplings of the bay water. Temporal trends in these inflow rates are an important basis for evaluating changes in PFOS and PFOA emissions in the Tokyo Bay catchment basin. A mixing model estimated the average concentrations of these compounds in the freshwater inflow to the bay, which were then multiplied by estimated freshwater inflow rates to obtain the inflow rates of these compounds. The receptor-oriented approach enabled us to comprehensively cover inflow to the bay, including inflow via direct discharge to the bay. On a logarithmic basis, the rate of inflow for PFOS decreased gradually, particularly after 2006, whereas that for PFOA exhibited a marked stepwise decrease from 2006 to 2007. The rate of inflow for PFOS decreased from 730kg/y during 2004-2006 to 160kg/y in 2010, whereas that for PFOA decreased from 2000kg/y during 2004-2006 to 290kg/y in 2010. These reductions probably reflected reductions in the use and emission of these compounds and their precursors in the Tokyo Bay catchment basin. Our estimated per-person inflow rates (i.e., inflow rates divided by the estimated population in the basin) for PFOS were generally comparable to previously reported per-person waterborne emission rates in Japan and other countries, whereas those for PFOA were generally higher than previously reported per-person waterborne emission rates. A comparison with previous estimates of household emission rates of these compounds suggested that our inflow estimates included a considerable contribution from point industrial sources. Copyright © 2015. Published by Elsevier B.V.

  8. Monitoring of lightning activity based on simultaneous measurement of electric field and electric field-change in the Tokyo metropolitan area

    Science.gov (United States)

    Yamashita, K.; Ohya, H.; Takahashi, Y.; Sato, M.

    2017-12-01

    Main objective of this study is nowcast of thunderstorm activity that causes extreme weather, such as torrential rain, based on lightning observation. Lightning observation has been focused on as an effective way for nowcast of thunderstorm activity. Spatial distribution of lightning discharge has been used as a proxy of the presence or absence of deep convection, which generates thunderstorm. We have constructed sensor network for lightning observation in the Tokyo metropolitan area, Japan, since 2013. In this network, VLF sensors (frequency range is 1 - 40 kHz) to measure electric field radiated from lightning discharges are distributed about 100 km apart. Additionally, slow antenna and electric field mill are also installed to detect electric field-change by lightning discharge. In this study, evaluations of not only spatial distribution but also scale distribution of lightning activity have been examined based on simultaneous measurement of electric field and electric field-change. As a scale of lightning discharge, charge moment change is derived. Preceding observation shows that there is extremely huge lightning whose scale is more than hundreds times bigger than that of averaged event. Estimation of scale for each lightning discharge would makes it possible to evaluate not only existence but also strength of atmospheric convection in thunderstorm area quantitatively. Based on lighting observation in the Tokyo metropolitan area, we start to construct new sensor network for real-time monitoring of lightning activity from this year. VLF sensors, slow antenna and electric field mill are mounted on real-time weather observation system named POTEKA developed by Meisei Electric Co., Ltd. and will be distributed in Metro Manila, Philippines under the 5-year project (SATREPS). At the presentation, observation in the Tokyo metropolitan area are summarized as a prototype for lightning observation that will be carried out in Metro Manila, Philippines.

  9. New maintenance strategy of Tokyo Electric Power Company and Fukushima Dai-ichi Nuclear Power Plant for effective ageing management and safe long-term operation

    International Nuclear Information System (INIS)

    Inagaki, Takeyuki; Yamashita, Norimichi

    2009-01-01

    Fukushima Dai-ichi Nuclear Power Plant is the oldest among three nuclear power plants owned and operated by Tokyo Electric Power Company, which consists of six boiling water reactor units. The commercial operation of Unit 1 was commenced in 1971 (37 years old) and Unit 6 in 1978 (29 years old). Currently ageing degradations of systems, structures and components are managed through maintenance programs, component replacement/refurbishment programs and long-term maintenance plans. The long-term maintenance plans are established through ageing management component replacement/refurbishment programs reviews performed before the 30th year of operation and they are for safe and reliable operation after 30 years (long-term operation). However the past maintenance actions and past component replacement/refurbishment programs were not always proactive and past operational experience and maintenance practices suggest that effective/proactive ageing management programs be introduced in earlier stage of the plant operation. In this circumstance, Tokyo Electric Power Company and Fukushima Dai-ichi Nuclear Power Plant are setting up a new maintenance strategy that includes 1) improving the normal maintenance programs by using ageing degradation data, 2) effective use of information on internal/external operational experience and maintenance practices related to ageing, and 3) proactive component/equipment refurbishment programs during a refreshment outage for safe and reliable long-term operation. To accomplish the goal of this strategy, strengthening engineering capability of plant staff members is a crucial required for the plant. The objective of this paper is to briefly explain main results ageing management reviews, past and current significant ageing issues and management programs against them, and the new maintenance strategy established by Tokyo Electric Power Company and Fukushima Dai-ichi Nuclear Power Plant. (author)

  10. Factors Affecting Customer’s Perception of Service Quality: Comparing Differences among Countries - Case study: Beauty salons in Bandung and Tokyo

    Directory of Open Access Journals (Sweden)

    Keiko Nakashima

    2012-01-01

    Full Text Available This paper examines a holistic study of analyzing several factors affecting service quality andtheir correlation with characteristic of customers based on value and life style. Furthermore,customer’s perception of service quality can be drawn from those relationships. Exploratoryfactor analysis and quantitative analysis is employed with case study of beauty salon serviceat Bandung and Tokyo. The results indicate how the quality of services is perceived differentlyby customers who have different value and life style, and also describe significant relationshipbetween value and life style with the affecting factors of service quality.Key words : service quality, value and life style, customer perception, beauty salon.

  11. Environmental radiation status in Bunkyo-ku, Tokyo, after the TEPCO Fukushima Dai-ichi Nuclear Power Plant disaster

    International Nuclear Information System (INIS)

    Ebisawa, Takao; Hirose, Seiichi; Furuta, Etsuko; Kusama, Keiji; Iimoto, Takeshi

    2013-01-01

    Bunkyo-ku is located in the eastern part of the metropolitan area of Tokyo, Japan, and is roughly 220 km south of the TEPCO Fukushima Dai-ichi Nuclear Power Plant. The population of the city was 201,079 as of August 1, 2012, and its area is 11.31 km 2 . The local government has officially been surveying the environmental radiation status after the disaster in response to numerous requests from its citizens. The radiation surveillance in this area has been technically guided by radiation protection specialists. The two main targets for surveillance are (1) the ambient radiation dose (microsieverts per hour) at all the school yards, public parks, and representative measurement points selected by the local government, and (2) the specific radioactivity (becquerels per kilogram) present in school lunch. These data have been reported to the citizens through the city website as well as in a bi-monthly report in the public relations magazine of the local government. This report presents the background status and technical information of the related activities, as well as the measured environmental radiation data. The ambient radiation dose in the city has been surveyed since July 2011. In the 1st period of surveillance (from July to August, 2012), over a total of 304 measurement points, the highest recorded value of the ambient radiation dose was 0.22 μSv h -1 at the height of 1 m from the ground, the lowest was 0.05 μSv h -1 , and the average was around 0.09 μSv h -1 . These values include the natural background dose rate detected by the energy compensation type surveymeters. In the most recent surveillance records, the maximum value recorded was 0.10, the minimum was 0.05, and 0.07 μSv h -1 was the average value. The specific radioactivity of drinking water has been monitored at local purification plants since the accident occurred. No water sample supplied to the city has exceeded the national limits for intake dose. The specific radioactivity of school lunch was

  12. Seismic wavefield imaging in the Tokyo metropolitan area, Japan, based on the replica exchange Monte Carlo method

    Science.gov (United States)

    Kano, Masayuki; Nagao, Hiromichi; Nagata, Kenji; Ito, Shin-ichi; Sakai, Shin'ichi; Nakagawa, Shigeki; Hori, Muneo; Hirata, Naoshi

    2017-04-01

    Earthquakes sometimes cause serious disasters not only directly by ground motion itself but also secondarily by infrastructure damage, particularly in densely populated urban areas. To reduce these secondary disasters, it is important to rapidly evaluate seismic hazards by analyzing the seismic responses of individual structures due to the input ground motions. Such input motions are estimated utilizing an array of seismometers that are distributed more sparsely than the structures. We propose a methodology that integrates physics-based and data-driven approaches in order to obtain the seismic wavefield to be input into seismic response analysis. This study adopts the replica exchange Monte Carlo (REMC) method, which is one of the Markov chain Monte Carlo (MCMC) methods, for the estimation of the seismic wavefield together with one-dimensional local subsurface structure and source information. Numerical tests show that the REMC method is able to search the parameters related to the source and the local subsurface structure in broader parameter space than the Metropolis method, which is an ordinary MCMC method. The REMC method well reproduces the seismic wavefield consistent with the true one. In contrast, the ordinary kriging, which is a classical data-driven interpolation method for spatial data, is hardly able to reproduce the true wavefield even at low frequencies. This indicates that it is essential to take both physics-based and data-driven approaches into consideration for seismic wavefield imaging. Then the REMC method is applied to the actual waveforms observed by a dense seismic array MeSO-net (Metropolitan Seismic Observation network), in which 296 accelerometers are continuously in operation with several kilometer intervals in the Tokyo metropolitan area, Japan. The estimated wavefield within a frequency band of 0.10-0.20 Hz is absolutely consistent with the observed waveforms. Further investigation suggests that the seismic wavefield is successfully

  13. Polychlorinated dioxins, furans, and biphenyls in blood of children and adults living in a dioxin-contaminated area in Tokyo

    Science.gov (United States)

    Uchiyama, Iwao; Hoshi, Shuji; Hijiya, Masaki; Miyata, Hideaki; Nagai, Masaki; Nakai, Satoshi; Yauchi, Mariko

    2010-01-01

    The soil of a residential area in Tokyo was found to contain dioxins, namely polychlorinated dioxins, furans, and dioxin-like biphenyls, the levels of which exceeded the environmental guideline [1,000 pg toxic equivalent (TEQ)/g] by up to 6.8 times. To assess the exposure levels of people living in this area and to study the possible relationship of blood dioxin concentrations of children with breast milk and/or formula feeding, a health survey was carried out in 2006, involving a total of 138 people, including 66 children aged 3–15 years, and blood dioxin concentrations and the characteristics and lifestyles of these people were analyzed. Mean ± standard error of the mean (SEM) of blood dioxin concentrations (pg/g-lipid) of group 1 (3–6 years old), group 2 (7–15 years old), and group 3 (≥16 years old) were 13 ± 1.9, 6.6 ± 0.65, and 10 ± 0.54, respectively. The congener/isomer profile of dioxins in blood samples differed markedly from that of the contaminated soil samples. According to the feeding mode of children, blood dioxin concentrations (pg/g-lipid) were 17 ± 2.9 for breast milk only, 7.4 ± 0.82 for both breast milk and formula, and 4.7 ± 1.1 for formula only, with a significant difference from one another. We conclude that people living in the dioxin-contaminated area are less likely to be exposed to excessive amounts of dioxins, and that blood dioxin concentrations of children aged 3–15 years seem to be strongly affected by breast feeding duration. Electronic supplementary material The online version of this article (doi:10.1007/s12199-010-0156-z) contains supplementary material, which is available to authorized users. PMID:21432212

  14. Post-Disaster Food and Nutrition from Urban Agriculture: A Self-Sufficiency Analysis of Nerima Ward, Tokyo.

    Science.gov (United States)

    Sioen, Giles Bruno; Sekiyama, Makiko; Terada, Toru; Yokohari, Makoto

    2017-07-10

    Background : Post-earthquake studies from around the world have reported that survivors relying on emergency food for prolonged periods of time experienced several dietary related health problems. The present study aimed to quantify the potential nutrient production of urban agricultural vegetables and the resulting nutritional self-sufficiency throughout the year for mitigating post-disaster situations. Methods : We estimated the vegetable production of urban agriculture throughout the year. Two methods were developed to capture the production from professional and hobby farms: Method I utilized secondary governmental data on agricultural production from professional farms, and Method II was based on a supplementary spatial analysis to estimate the production from hobby farms. Next, the weight of produced vegetables [t] was converted into nutrients [kg]. Furthermore, the self-sufficiency by nutrient and time of year was estimated by incorporating the reference consumption of vegetables [kg], recommended dietary allowance of nutrients per capita [mg], and population statistics. The research was conducted in Nerima, the second most populous ward of Tokyo's 23 special wards. Self-sufficiency rates were calculated with the registered residents. Results : The estimated total vegetable production of 5660 tons was equivalent to a weight-based self-sufficiency rate of 6.18%. The average nutritional self-sufficiencies of Methods I and II were 2.48% and 0.38%, respectively, resulting in an aggregated average of 2.86%. Fluctuations throughout the year were observed according to the harvest seasons of the available crops. Vitamin K (6.15%) had the highest self-sufficiency of selected nutrients, while calcium had the lowest (0.96%). Conclusions : This study suggests that depending on the time of year, urban agriculture has the potential to contribute nutrients to diets during post-disaster situations as disaster preparedness food. Emergency responses should be targeted

  15. Efectos adversos de fármacos antirretrovirales en cohorte de niños hijos de gestante VIH positiva: transmisión vertical, efectos adversos de fármacos antirretrovirales, malformaciones congénitas y desarrollo ponderoestatural en una cohorte de niños expuestos y no infectados hijos de gestante VIH positiva

    OpenAIRE

    Fernández Ibieta, María

    2011-01-01

    En el desarrollo de esta tesis doctoral se analizan la transmisión vertical (TV) y los efectos adversos de los fármacos antirretrovirales, tanto hematológicos como bioquímicos, así como las malformaciones congénitas y el desarrollo ponderoestatural de los niños de la cohorte perinatal de Madrid, relacionada y subvencionada por la fundación FIPSE (Fundación para la investigación y la Prevención del SIDA en España. Esta cohorte se inició en el año 2000 con el objetivo de seguir prospectivamente...

  16. Forma no clásica de hiperplasia adrenal congénita en la niñez y adolescencia Non-classic way of congenital adrenal hyperplasia in childhood and adolescence

    Directory of Open Access Journals (Sweden)

    Francisco Carvajal Martínez

    2010-04-01

    Full Text Available INTRODUCCIÓN: la hiperplasia adrenal congénita es un trastorno hereditario de la esteroidogénesis suprarrenal, trasmitido por mutaciones genéticas con carácter autosómico recesivo, las cuales afectan las enzimas que intervienen en la biosíntesis del cortisol. La causa la constituye en 90 a 95 % de los casos la deficiencia de la enzima 21 hidroxilasa. OBJETIVO: exponer la experiencia de los autores de este trabajo en la forma no clásica de esta enfermedad. MÉTODOS: se realizó la caracterización de 7 pacientes diagnosticados en la sala de endocrinología pediátrica del Instituto Nacional de Endocrinología, ubicada en el Hospital Pediátrico del Cerro, durante el período 1998-2008. Todos los pacientes pertenecían al sexo femenino. RESULTADOS: los síntomas se iniciaron a una edad promedio de 8,8 años y más de la mitad de los casos presentaron pubarquia precoz. La menarquia se produjo a una edad media de 10,7 años. Se logró el diagnóstico bioquímico al obtenerse valores elevados de 17 hidroxiprogesterona (en condiciones basales. Se emplearon distintas modalidades de tratamiento según la edad de cada paciente y los síntomas predominantes en cada caso. CONCLUSIONES: se corroboró la mayor frecuencia de diagnóstico de esta enfermedad en el sexo femenino, así como la importancia del estudio y el seguimiento ante un paciente con pubarquia precoz.INTRODUCTION: the congenital adrenal hyperplasia is an inherited disorder of suprarenal esteroidogenesis, transmitted by genetic mutations with a autosomal recessive character affecting the enzymes intervening in cortisol biosynthesis. In the 90 to 95% of cases, the cause is a deficiency of Hydroxylase enzyme 21. OBJECTIVE: to show the current paper authors' experience in the non-classic way of this entity. METHODS: we made a characterization of 7 female patients diagnosed in the Children Endocrinology Ward of the National Institute of Endocrinology located in the Children Hospital, Cerro

  17. Testing of an automatic outdoor gamma ambient dose-rate surveillance system in Tokyo and its calibration using measured deposition after the Fukushima nuclear accident

    International Nuclear Information System (INIS)

    Zhang, Weihua; Korpach, Ed; Berg, Rodney; Ungar, Kurt

    2013-01-01

    An in-situ fixed point radioactivity surveillance network has been developed at the Radiation Protection Bureau, Health Canada. The network consists of a number of spectrometric NaI(Tl) detectors measuring, in real-time, ambient gamma dose-rate. The present paper describes the gamma dose-rate monitoring by one detector installed at the Canadian embassy in Tokyo during the Fukushima nuclear accident. Soil samples were collected for the measurement of fallout fission products inventories at each location where the NaI(Tl) detector was installed. The gamma-ray attenuation by the soil matrix was estimated by the information on the depth distribution of 137 Cs activities. The study demonstrated that the gamma dose-rates measured by the field NaI(Tl) spectrometric method agreed well with the laboratory results estimated by the inventories of fallout fission products deposited in the soil and the vertical distribution of 137 Cs in the soil. -- Highlights: ► An automatic outdoor gamma ambient dose-rate surveillance system in Tokyo. ► Monitoring of increased ambient gamma dose-rate during the Fukushima accident. ► Laboratory soil sample fallout fission product inventory analysis. ► NaI(Tl) dose-rate calibration coefficient testing by contaminated soil inventories

  18. High-resolution 3D seismic reflection imaging across active faults and its impact on seismic hazard estimation in the Tokyo metropolitan area

    Science.gov (United States)

    Ishiyama, Tatsuya; Sato, Hiroshi; Abe, Susumu; Kawasaki, Shinji; Kato, Naoko

    2016-10-01

    We collected and interpreted high-resolution 3D seismic reflection data across a hypothesized fault scarp, along the largest active fault that could generate hazardous earthquakes in the Tokyo metropolitan area. The processed and interpreted 3D seismic cube, linked with nearby borehole stratigraphy, suggests that a monocline that deforms lower Pleistocene units is unconformably overlain by middle Pleistocene conglomerates. Judging from structural patterns and vertical separation on the lower-middle Pleistocene units and the ground surface, the hypothesized scarp was interpreted as a terrace riser rather than as a manifestation of late Pleistocene structural growth resulting from repeated fault activity. Devastating earthquake scenarios had been predicted along the fault in question based on its proximity to the metropolitan area, however our new results lead to a significant decrease in estimated fault length and consequently in the estimated magnitude of future earthquakes associated with reactivation. This suggests a greatly reduced seismic hazard in the Tokyo metropolitan area from earthquakes generated by active intraplate crustal faults.

  19. A study of trace element concentrations in human hair of some local populations in Japan. I. Inhabitants of the Tokyo metropolitan area

    International Nuclear Information System (INIS)

    Imahori, A.; Fukushima, I.; Shiobara, S.; Terai, M.

    1979-01-01

    By applying instrumental neutron activation analysis techniques, a survey was carried out to determine the levels of a variety of trace element concentrations in human hair of the inhabitants of the Tokyo metropolitan area. A total of 202 scalp hair samples were collected from the inhabitants of the residential district in the western part of the Tokyo metropolitan area. The donors were divided into five age groups, ranging from pre-school age to sixty years and above. Each group consisted of twenty males and twenty or more females. The sampling method and washing procedure recommended by the IAEA Advisory Group on the applications of nuclear methods in environmental research were strictly followed. Irradiation of the samples was made in the Rikkyo University 100-kW TRIGA MARK II reactor. By using several combinations of irradiation time, cooling time and counting time, the following 37 elements were quantitatively analysed: Ag, Al, As, Au, Ba, Br, Ca, Cd, Ce, Cl, Co, Cr, Cu, Fe, Hg, I, K, La, Mg, Mn, Mo, Na, Ni, Rb, S, Sb, Sc, Se, Sm, Sn, Te, Ti, U, V, W and Zn. NBS standard reference orchard leaves and bovine liver were also analysed in the course of the hair analysis to assess the precision of the analytical techniques. (author)

  20. [Projects to accelerate the practical use of innovative medical devices to collaborate with TWIns, Center for Advanced Biomedical Sciences, Waseda University and School of Engineering, The University of Tokyo].

    Science.gov (United States)

    Niimi, Shingo; Umezu, Mitsuo; Iseki, Hiroshi; Harada, Hiroshi Kasanuki Noboru; Mitsuishi, Mamoru; Kitamori, Takehiko; Tei, Yuichi; Nakaoka, Ryusuke; Haishima, Yuji

    2014-01-01

    Division of Medical Devices has been conducting the projects to accelerate the practical use of innovative medical devices to collaborate with TWIns, Center for Advanced Biomedical Sciences, Waseda University and School of Engineering, The University of Tokyo. The TWIns has been studying to aim at establishment of preclinical evaluation methods by "Engineering Based Medicine", and established Regulatory Science Institute for Medical Devices. School of Engineering, The University of Tokyo has been studying to aim at establishment of assessment methodology for innovative minimally invasive therapeutic devices, materials, and nanobio diagnostic devices. This report reviews the exchanges of personnel, the implement systems and the research progress of these projects.

  1. IAEA Expert Team Completes Mission to Review Japan's Nuclear Power Plant Safety Assessment Process, 31 January 2012, Tokyo, Japan

    International Nuclear Information System (INIS)

    2012-01-01

    Full text: A team of international nuclear safety experts today completed a review of Japan's two-stage process for assessing nuclear safety at the nation's nuclear power plants. The team began its work on 23 January and delivered a Preliminary Summary Report to Japanese officials today and plans to finish the final report by the end of February. National safety assessments and their peer review by the IAEA are a key component of the IAEA's Action Plan on Nuclear Safety, which was approved by the Agency's 152 Member States following last year's nuclear accident at Fukushima Daiichi Nuclear Power Station. At the request of the Government of Japan, the International Atomic Energy Agency (IAEA) organized a 10-person team to review the Japanese Nuclear and Industrial Safety Agency's (NISA) approach to the Comprehensive Assessments for the Safety of Existing Power Reactor Facilities and how NISA examines the results submitted by nuclear operators. The IAEA safety review mission consisted of five IAEA and three international nuclear safety experts. To help its review, the team held meetings in Tokyo with officials from NISA, the Japanese Nuclear Energy Safety (JNES) Organization, and the Kansai Electric Power Company (KEPCO), and the team visited the Ohi Nuclear Power Station to see an example of how Japan's Comprehensive Safety Assessment is being implemented by nuclear operators. 'We concluded that NISA's instructions to power plants and its review process for the Comprehensive Safety Assessments are generally consistent with IAEA Safety Standards', said team leader James Lyons, director of the IAEA's Nuclear Installation Safety Division. In its Preliminary Summary Report delivered today, the team highlighted a number of good practices and identified some improvements that would enhance the overall effectiveness of the Comprehensive Safety Assessment process. Good practices identified by the mission team include: Based on NISA instructions and commitments of the

  2. Estimated dietary intake of radionuclides and health risks for the citizens of Fukushima City, Tokyo, and Osaka after the 2011 nuclear accident.

    Science.gov (United States)

    Murakami, Michio; Oki, Taikan

    2014-01-01

    The radionuclides released from the Fukushima Daiichi nuclear power plant in 2011 pose a health risk. In this study, we estimated the 1st-year average doses resulting from the intake of iodine 131 (131I) and cesium 134 and 137 (134Cs and 137Cs) in drinking water and food ingested by citizens of Fukushima City (∼50 km from the nuclear power plant; outside the evacuation zone), Tokyo (∼230 km), and Osaka (∼580 km) after the accident. For citizens in Fukushima City, we considered two scenarios: Case 1, citizens consumed vegetables bought from markets; Case 2, citizens consumed vegetables grown locally (conservative scenario). The estimated effective doses of 134Cs and 137Cs agreed well with those estimated through market basket and food-duplicate surveys. The average thyroid equivalent doses due to ingestion of 131I for adults were 840 µSv (Case 1) and 2700 µSv (Case 2) in Fukushima City, 370 µSv in Tokyo, and 16 µSv in Osaka. The average effective doses due to 134Cs and 137Cs were 19, 120, 6.1, and 1.9 µSv, respectively. The doses estimated in this study were much lower than values reported by the World Health Organization and the United Nations Scientific Committee on the Effects of Atomic Radiation, whose assessments lacked validation and full consideration of regional trade in foods, highlighting the importance of including regional trade. The 95th percentile effective doses were 2-3 times the average values. Lifetime attributable risks (LARs) of thyroid cancers due to ingestion were 1.7-37×10-6 (Case 1) and5.6-79×10-6 (Case 2) in Fukushima City, 0.73-13×10-6 in Tokyo, and 0.04-0.49×10- 6 in Osaka. The contributions of LARs of thyroid cancers due to ingestion were 5.4%-11% of all exposure (Case 1) and 11%-25% (Case 2) in Fukushima City [corrected].

  3. Estimated dietary intake of radionuclides and health risks for the citizens of Fukushima City, Tokyo, and Osaka after the 2011 nuclear accident.

    Directory of Open Access Journals (Sweden)

    Michio Murakami

    Full Text Available The radionuclides released from the Fukushima Daiichi nuclear power plant in 2011 pose a health risk. In this study, we estimated the 1st-year average doses resulting from the intake of iodine 131 (131I and cesium 134 and 137 (134Cs and 137Cs in drinking water and food ingested by citizens of Fukushima City (∼50 km from the nuclear power plant; outside the evacuation zone, Tokyo (∼230 km, and Osaka (∼580 km after the accident. For citizens in Fukushima City, we considered two scenarios: Case 1, citizens consumed vegetables bought from markets; Case 2, citizens consumed vegetables grown locally (conservative scenario. The estimated effective doses of 134Cs and 137Cs agreed well with those estimated through market basket and food-duplicate surveys. The average thyroid equivalent doses due to ingestion of 131I for adults were 840 µSv (Case 1 and 2700 µSv (Case 2 in Fukushima City, 370 µSv in Tokyo, and 16 µSv in Osaka. The average effective doses due to 134Cs and 137Cs were 19, 120, 6.1, and 1.9 µSv, respectively. The doses estimated in this study were much lower than values reported by the World Health Organization and the United Nations Scientific Committee on the Effects of Atomic Radiation, whose assessments lacked validation and full consideration of regional trade in foods, highlighting the importance of including regional trade. The 95th percentile effective doses were 2-3 times the average values. Lifetime attributable risks (LARs of thyroid cancers due to ingestion were 1.7-37×10-6 (Case 1 and5.6-79×10-6 (Case 2 in Fukushima City, 0.73-13×10-6 in Tokyo, and 0.04-0.49×10- 6 in Osaka. The contributions of LARs of thyroid cancers due to ingestion were 5.4%-11% of all exposure (Case 1 and 11%-25% (Case 2 in Fukushima City [corrected].

  4. Veneetsia filmifestival lõppes Iraani võiduga / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2000-01-01

    Kuldlõvi sai Jafar Panahi mängufilm "Ring" ("Dayereh"), žürii suure preemia USA režissööri Julian Schnabeli "Enne kui öö saabub" ("Before Night Falls"), parima stsenaariumi preemia itaallase Marco Tullio Giordana "Sada sammu" ("I cento passi")

  5. XXI Pärnu filmifestival tuleb valikkavaga / Lii Bärlin

    Index Scriptorium Estoniae

    Bärlin, Lii

    2007-01-01

    24. ja 25. juulil näidatakse huvilistele Rakvere Teatrikinos XXI Pärnu filmifestivali raames filmide valikkava. Filme soovitavad Mark Soosaar, Rakvere Teatrikino projektijuht Jaanus Kaasik. Lisatud filmide kava

  6. XXI sajandi esimene Berlinale : 51. Berliini filmifestival 7.-18. veebruar 2001 / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2001-01-01

    51. Berliini filmifestivalist, selle senisest direktorist Moritz de Hadelnist, Fritz Langist (1890-1976) ja tema filmide retrospektiivist, Renny Bartlett'i dokumentaalfilmist "Eisenstein" ja teistest huvitavamatest filmidest. Ka olulisemate auhinnatute nimekiri

  7. Üks, kaks, kolm - ja Cannes'i filmifestival! / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2008-01-01

    14. mail avatud Cannes'i 61. rahvusvahelisest filmifestivalist, võistlusprogrammist. Eesti osaleb filmiturul nelja filmiga : "Georg", "Sügisball", Kuhu põgenevad hinged", "Mina olin siin" ning lisaks Ukraina-Eesti koostööfilm "Kurja saatuse mängukannid" ("Prikalna kazka")

  8. "A & A" jõulukalender. Helsingi "Armastuse ja anarhia" filmifestival võib pankrotistuda / Jaak Kilmi

    Index Scriptorium Estoniae

    Kilmi, Jaak, 1973-

    2004-01-01

    Helsingi festivalilt "Armastus ja Anarhia". Lähemalt kahest filmist - saksa-türgi režissööri Fatih Akini "Vastu seina" ("Gegen die Wand") ja argentiinlanna Lucrecia Marteli "Püha tüdruk" ("La Nina santa")

  9. Muusikamaailm : Gran Teatre del Liceu taassünd. Orkestrikonverents Tokyos ja vietnami helilooja Phan. Konkursid Kölnis ja Düsseldorfis. Suri fado-lauljatar Amalia Rodrigues / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    1999-01-01

    Barcelonas avas 7. okt. taas uksed Gran Teatre del Liceu, mis hävis tulekahjus 1994.a., teatri hooaja kavast, esinejatest. Jaapanis Tokyos toimunud Aasia maade orkestrikonverentsist. Kölni rahvusvahelise viiuldajate konkursi võitjatest, noorte muusikute nüüdismuusikaansamblite võistlusest Düsseldorfis. A.Rodrigues" lauljategevusest

  10. Rubella and congenital rubella syndrome: global update La rubéola y el síndrome de rubéola congénita: resumen de la situación actual en el mundo

    Directory of Open Access Journals (Sweden)

    Susan E. Robertson

    2003-11-01

    Full Text Available Worldwide, it is estimated that there are more than 100 000 infants born with congenital rubella syndrome (CRS each year. In 1998, standard case definitions for surveillance of CRS and rubella were developed by the World Health Organization (WHO. In 2001, 123 countries/territories reported a total of 836 356 rubella cases. In the future more countries are expected to report on rubella as a global measles/rubella laboratory network is further developed under the coordination of the WHO. Operational research is being conducted to improve rubella surveillance. This includes projects on initiating CRS surveillance, comparative studies on diagnostic laboratory methods, and molecular epidemiology research to expand the global understanding of patterns of rubella virus circulation. In 1996 a WHO survey found that 78 of 214 reporting countries/territories (36% were using rubella vaccine in their routine immunization services. By the end of 2002 a total of 124 of the 214 counties/territories (58% were using rubella vaccine. Rubella vaccine use varies by stage of economic development: 100% for industrialized countries, 71% for countries with economies in transition, and 48% for developing countries. A safe and effective rubella vaccine is available, and there are proven vaccination strategies for preventing rubella and CRS. A WHO position paper provides guidance on programmatic aspects of rubella vaccine introduction. The introduction of rubella vaccine is cost-effective and cost-beneficial but requires ongoing strengthening of routine immunization services and surveillance systems.Se calcula que cada año nacen en el mundo más de 100 000 niños con síndrome de rubéola congénita (SRC. La Organización Mundial de la Salud (OMS estandarizó en 1998 las definiciones de casos para la vigilancia del SRC y de la rubéola. En 2001, 123 países o territorios notificaron 836 356 casos de rubéola y se espera que el número de países se incremente a medida que

  11. Malformação congénita das vias aéreas pulmonares – Experiência de cinco centros

    Directory of Open Access Journals (Sweden)

    Gustavo Rocha

    2007-07-01

    Full Text Available Resumo: Introdução: O espectro clínico da malformação adenomatóide cística pulmonar congénita (MACPC va-ria desde lesões assintomáticas e dificuldade respiratória no recém-nascido a hidrópsia fetal.Objectivos: Avaliação da casuística de MACPC, real-çando a história natural, tratamento e evolução.Material e métodos: Análise retrospectiva dos processos clínicos de todos os recém-nascidos com o diagnóstico de MACPC, admitidos nas unidades de cui-dados intensivos neonatais de cinco centros terciários do Norte de Portugal, entre 1996 e 2005.Resultados: Foram identificados 15 recém-nascidos, 9 F/6 M, peso ao nascimento 3100 g (645-3975, idade gestacional de 38 semanas (24-40. A incidên-cia de MACPC foi de 1:9300 nascimentos. Onze (73% recém-nascidos apresentaram diagnóstico pré-natal de lesão pulmonar cística pelas 22 semanas (19-30. Esta ocorreu no hemitórax direito em seis (40% casos e no lado esquerdo em 9 (60%. Foi documentada regressão in utero da lesão em dois casos. Foi necessária intervenção ante-natal (pleu-rocentese e colocação de derivação toraco-amnió-tica num feto com hidrópsia fetal. Ao nascimento, cinco recém-nascidos apresentaram radiografia de tórax dentro da normalidade, sendo a tomografia axial computorizada diagnóstica da lesão. Três (20% recém-nascidos tornaram-se sintomáticos durante o período neonatal (dificuldade respiratória e um (7% após o período neonatal (pneumotórax espon-tâneo. Dois (13% faleceram. Seis (40% doentes foram submetidos a toracotomia e exérese da lesão. O estudo anatomopatológico demonstrou acha-dos definitivos de MACPC (classificação de Stoker: tipo I=4; tipo II=1; tipo III=2. Oito (53% crianças mantiveram-se assintomáticas e permane-cem em vigilância clínica.Conclusões: A MACPC com diagn

  12. Malformação congénita das vias aéreas pulmonares: Experiência de cinco centros Congenital cystic adenomatoid malformation of the lung: The experience of five medical centres

    Directory of Open Access Journals (Sweden)

    Gustavo Rocha

    2007-07-01

    Full Text Available Introdução: O espectro clínico da malformação adenomatóide cística pulmonar congénita (MACPC varia desde lesões assintomáticas e dificuldade respiratóriano recém-nascido a hidrópsia fetal. Objectivos: Avaliação da casuística de MACPC, realçando a história natural, tratamento e evolução. Material e métodos: Análise retrospectiva dos processos clínicos de todos os recém-nascidos com o diagnóstico de MACPC, admitidos nas unidades de cuidados intensivos neonatais de cinco centros terciários do Norte de Portugal, entre 1996 e 2005. Resultados: Foram identificados 15 recém-nascidos, 9F/6M, peso ao nascimento 3100 g (645-3975, idade gestacional de 38 semanas (24-40. A incidência de MACPC foi de 1:9300 nascimentos. Onze (73% recém-nascidos apresentaram diagnóstico pré-natal de lesão pulmonar cística pelas 22 semanas (19-30. Esta ocorreu no hemitórax direito em seis (40% casos e no lado esquerdo em 9 (60%. Foi documentada regressão in utero da lesão em dois casos. Foi necessária intervenção ante-natal (pleurocentese e colocação de derivação toraco-amniótica num feto com hidrópsia fetal. Ao nascimento, cinco recém-nascidos apresentaram radiografia de tórax dentro da normalidade, sendo a tomografia axial computorizada diagnóstica da lesão. Três (20% recém-nascidos tornaram-se sintomáticos durante o período neonatal (dificuldade respiratória e um (7% após o período neonatal (pneumotórax espontâneo. Dois (13% faleceram. Seis (40% doentes foram submetidos a toracotomia e exérese da lesão. O estudo anatomopatológico demonstrou achados definitivos de MACPC (classificação de Stoker: tipo I = 4; tipo II = 1; tipo III = 2. Oito (53% crianças mantiveram-se assintomáticas e permanecem em vigilância clínica. Conclusões: A MACPC com diagnóstico pré-natal tem bom prognóstico na ausência de sofrimento fetal; uma radiografia de tórax sem alterações ao nascimento não exclui MACPC; o tratamento da

  13. SEISMIC BEHAVIOR OF THE TOKYO BAY AREA DURING THE 2011 OFF THE PACIFIC COAST OF TOHOKU EARTHQUAKE USING DOWNHOLE ARRAY RECORDS

    Science.gov (United States)

    Ikeda, Takaaki; Konagai, Kazuo; Katagiri, Toshihiko

    Underground motions within a hard diluvial stratum were obtained in the March 11th 2011 Great East Japan Earthquake at a downhole in the Tokyo Bay area, which has suffered serious sand-liquefaction over its long 42km2 stretch. The motions in the diluvial sand deposit are characterized by their (1) long dura-tion times with 6 to 8s components surpassing others, (2) moderate amplitude of 51.1 cm/s2 in PGA, which is estimated to have resulted in moderate average strains of 8 to 9 × 10-4 and 5 to 7 × 10-4 over shal-low -2 to -30m and deep -30 to -77m soil deposits, respectively. The peak strain reached in the interior of soil was estimated to be about 1.3 × 10-3.

  14. Experiences of Response Measures against the 4 Suspected Cases of Ebola Virus Disease from West Africa in the National Center for Global Health and Medicine, Tokyo, Japan.

    Science.gov (United States)

    Kutsuna, Satoshi; Yamamoto, Kei; Takeshita, Nozomi; Hayakawa, Kayoko; Kato, Yasuyuki; Kanagawa, Shuzo; Sugiki, Yuko; Ohmagari, Norio

    2018-01-23

    In Japan, infectious diseases are classified into 4 types based on how contagious and severe the pathogens are, and Ebola virus disease (EVD) is categorized as a category 1 infectious disease. The National Center for Global Health and Medicine in Tokyo, Japan, is designated as a specified hospital for category 1 infectious disease patients and has experienced 4 probable cases of EVD from West Africa. Even after the outbreak in West Africa is ended, we should continue to pay attention for new EVD outbreaks. Increasing the number of infectious disease specialists with the proper knowledge of viral hemorrhagic fever, including EVD, is a common problem for infectious disease physicians working in Japan, the academic society, and the government.

  15. Classification of M~7 earthquakes in Tokyo Metropolitan area since 1885 - The 1921 Ibaraki-ken Nambu and 1922 Uraga channel earthquakes

    Science.gov (United States)

    Ishibe, T.; Satake, K.; Shimazaki, K.; Murotani, S.; Nishiyama, A.

    2011-12-01

    S-P times, focal mechanism solutions from initial motion, and seismic intensity distribution show that the 1921 Ibaraki-ken Nambu earthquake (M 7.0) and the 1922 Uraga channel earthquake (M 6.8) both occurred within the subducting Philippine Sea plate beneath the Tokyo Metropolitan area. The Tokyo Metropolitan area is situated in a tectonically complex region; The Philippine Sea plate (PHS) subducts from south, while the Pacific plate (PAC) subducts from east below PHS. As a result, various types of earthquakes occur in this region. They are classified into: shallow crustal earthquakes, intraplate (slab) earthquakes within PHS, within PAC, and interplate earthquakes between continental plate and PHS, and between PHS and PAC. The probability of the large earthquakes with magnitude (M)~7 is high; Earthquake Research Committee calculated the probability of occurrence during the next 30 years as 70 %, based on the fact that five M~7 earthquakes (the 1894 Meiji Tokyo, 1895 and 1921 Ibaraki-ken Nambu, 1922 Uraga Channel, and 1987 Chiba-ken Toho-oki earthquakes) occurred since 1885. However, types of these earthquakes except for the 1987 earthquake are not well known due to low quality of data. It is important to classify these earthquakes into above-described intraplate or interplate earthquakes. The Ibaraki-ken Nambu earthquake occurred on 8 December, 1921 and caused damage such as fissures on road, tumble of gravestones especially in the northwestern Chiba and southwestern Ibaraki prefectures. The focal depth was estimated to be around 55 km using S-P times of old seismograms or JMA reports, suggesting that this earthquake was probably a slab earthquake within PHS. Seismic intensity distribution supports this result; seismic intensity anomalies characterizing the PAC slab earthquakes are not recognized. Furthermore, initial motion focal mechanisms using HASH algorithm (Hardebeck and Shearer, 2002) are strike-slip types, even if the uncertainty of hypocenter locations

  16. Concentration of small ions measured at the center of Tokyo, at the summit of Mt. Fuji, and over the Pacific Ocean

    Science.gov (United States)

    Miura, K.; Ueda, S.; Nagaoka, N.; Fukawa, A.; Nagano, K.; Kobayashi, H.; Yasuda, H.; Yajima, K.; Furutani, H.; Uematsu, M.

    2012-12-01

    /Introduction/ It has been proposed that climate could be affected by changes in cloudiness caused by variations in the intensity of galactic cosmic rays in the atmosphere. The cause of it is considered as a new particle formation with ion induced nucleation. The ion induced nucleation is occurred under the low concentration of particles and high concentration of ions, but there are a few reports. Then we have observed small ions, aerosol size distributions, radon concentrations, and intensity of cosmic rays at the summit of Mt. Fuji simultaneously. We also observed the similar elements at the center of Tokyo and over the Pacific Ocean. /Methods/ Observations were performed in summer in 2010 and 2011 at the summit (3776m ASL) and in summer in 2011 at Tarobo (1290m ASL), at the base of the Mt. Fuji and from autumn in 2010 to summer 2011 at the center of Tokyo, and from 1st December 2011 to 6th March 2012 on the R/V Hakuho Maru over the Pacific Ocean. Small ions were measured with the Gerdien type meter (COM-3400). The critical mobility was set 0.7 cm2/V/s and we measured positive and negative ions alternately. Size distributions from 4.4 to 5000 nm in diameter were measured with a scanning mobility particle sizer (SMPS, TSI 3936N25 or 3936L22) and an optical particle counter (OPC, RION KR12 or KC01D). Radon concentration was calculated from concentration of radioactive aerosols collected on a filter. Small ions are generated with ionization of air by cosmic rays or radiation from radioactive substances. Small ions are lost by various mechanisms such as ion-ion recombination and ion-aerosol attachment. /Results and Discussion/ Hourly averaged concentration often showed the diurnal pattern of high in the early morning and low in the evening at Kagurazaka, Tarobo, and the summit in 2010. However, the different pattern of low in the early morning and high in the evening was often observed at the summit in 2011. This pattern had observed by some investigaters. New

  17. Estimating the probability distribution of the incubation period for rabies using data from the 1948-1954 rabies epidemic in Tokyo.

    Science.gov (United States)

    Tojinbara, Kageaki; Sugiura, K; Yamada, A; Kakitani, I; Kwan, N C L; Sugiura, K

    2016-01-01

    Data of 98 rabies cases in dogs and cats from the 1948-1954 rabies epidemic in Tokyo were used to estimate the probability distribution of the incubation period. Lognormal, gamma and Weibull distributions were used to model the incubation period. The maximum likelihood estimates of the mean incubation period ranged from 27.30 to 28.56 days according to different distributions. The mean incubation period was shortest with the lognormal distribution (27.30 days), and longest with the Weibull distribution (28.56 days). The best distribution in terms of AIC value was the lognormal distribution with mean value of 27.30 (95% CI: 23.46-31.55) days and standard deviation of 20.20 (15.27-26.31) days. There were no significant differences between the incubation periods for dogs and cats, or between those for male and female dogs. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. [Introduction of computerized anesthesia-recording systems and construction of comprehensive medical information network for patients undergoing surgery in the University of Tokyo Hospital].

    Science.gov (United States)

    Kitamura, Takayuki; Hoshimoto, Hiroyuki; Yamada, Yoshitsugu

    2009-10-01

    The computerized anesthesia-recording systems are expensive and the introduction of the systems takes time and requires huge effort. Generally speaking, the efficacy of the computerized anesthesia-recording systems on the anesthetic managements is focused on the ability to automatically input data from the monitors to the anesthetic records, and tends to be underestimated. However, once the computerized anesthesia-recording systems are integrated into the medical information network, several features, which definitely contribute to improve the quality of the anesthetic management, can be developed; for example, to prevent misidentification of patients, to prevent mistakes related to blood transfusion, and to protect patients' personal information. Here we describe our experiences of the introduction of the computerized anesthesia-recording systems and the construction of the comprehensive medical information network for patients undergoing surgery in The University of Tokyo Hospital. We also discuss possible efficacy of the comprehensive medical information network for patients during surgery under anesthetic managements.

  19. EFFECTS OF LONG-TIME COMMUTING AND LONG-HOUR WORKING ON LIFESTYLE AND MENTAL HEALTH AMONG SCHOOL TEACHERS IN TOKYO, JAPAN.

    Science.gov (United States)

    Nomoto, Marino; Hara, Akiko; Kikuchi, Kimiyo

    2015-06-01

    The objective of this study was to investigate the effects of long-time commuting and long-hour working on lifestyle including sleeping, physical exercise, breakfast, smoking, alcohol intake and mental health. In this cross-sectional study, data were collected from 146 school teachers in Tokyo. The binary associations of commuting time and working hours with lifestyle, mental stress measured by the General Health Questionnaire (GHQ) and stress coping measured by the Sense of Coherence (SOC) scores were examined. The Chi-square test was used for statistical analyses. Our results indicated that the mean commuting time and working hours per week of the respondents were 42.1 (SD 22.5) minutes and 50.4 (SD 8.6) hours, respectively. Longer commuting time was significantly associated with shorter working hours (p = 0.023), less physical exercise (p health questionnaire; sense of coherence

  20. The development and piloting of a leadership questionnaire for general dental practitioners: preliminary results from the North West of England and Tokyo.

    Science.gov (United States)

    Brocklehurst, P; O'Malley, L; Hill, H; Ozaki, T; Nomura, M; Matsuda, R

    2014-11-01

    Key reforms in England and Japan have called for greater clinical leadership from general dental practitioners to deliver improvements in the quality of care for patients. In England, the reorganisation of the National Health Service has led to the development of Local Professional Networks to ensure services are clinically led, patient and outcome focused. In Japan, the rapidly changing demographics have led to calls for general dental practitioners to become more active in meeting the emerging population health challenges. Both require engagement at a strategic and a local level. However, little is known about what is meant by clinical leadership in dentistry or what training needs exist. The aim of this study was to develop and pilot a questionnaire to understand what general dental practitioners feel is important about clinical leadership and how they rate themselves. A 61-item questionnaire was developed from the literature, an earlier qualitative study and refined through cognitive interviews. Questionnaires were distributed to general dental practitioners across the North West of England and Tokyo, using random sequence generation. For each item, the participant had to record whether they thought the statement was an important component of clinical leadership and how they rated themselves. Both were rated using a seven-point Likert scale. Data reduction was undertaken using principal component analysis to examine for factor loadings within the questionnaire. Differences in mean scores were also used to highlight substantive differences in how general dental practitioners rated the different components of leadership and how they rated themselves. The response rate for the pilot was low (22.9% and 7.5% for North West and Tokyo respectively). The items that were considered to be important in leadership reduced to two components in the North West (accounting for 62.1% of the total variance): 'How to lead' and 'How not to lead'. In Tokyo, 56.4% of the total