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Sample records for tippy tap hand-washing

  1. Hand washing promotion for preventing diarrhoea

    Science.gov (United States)

    Ejemot-Nwadiaro, Regina I; Ehiri, John E; Arikpo, Dachi; Meremikwu, Martin M; Critchley, Julia A

    2015-01-01

    Background Diarrhoea accounts for 1.8 million deaths in children in low- and middle-income countries (LMICs). One of the identified strategies to prevent diarrhoea is hand washing. Objectives To assess the effects of hand washing promotion interventions on diarrhoeal episodes in children and adults. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register (27 May 2015); CENTRAL (published in the Cochrane Library 2015, Issue 5); MEDLINE (1966 to 27 May 2015); EMBASE (1974 to 27 May 2015); LILACS (1982 to 27 May 2015); PsycINFO (1967 to 27 May 2015); Science Citation Index and Social Science Citation Index (1981 to 27 May 2015); ERIC (1966 to 27 May 2015); SPECTR (2000 to 27 May 2015); Bibliomap (1990 to 27 May 2015); RoRe, The Grey Literature (2002 to 27 May 2015); World Health Organization (WHO) International Clinical Trial Registry Platform (ICTRP), metaRegister of Controlled Trials (mRCT), and reference lists of articles up to 27 May 2015. We also contacted researchers and organizations in the field. Selection criteria Individually randomized controlled trials (RCTs) and cluster-RCTs that compared the effects of hand washing interventions on diarrhoea episodes in children and adults with no intervention. Data collection and analysis Three review authors independently assessed trial eligibility, extracted data, and assessed risk of bias. We stratified the analyses for child day-care centres or schools, community, and hospital-based settings. Where appropriate, incidence rate ratios (IRR) were pooled using the generic inverse variance method and random-effects model with 95% confidence intervals (CIs). We used the GRADE approach to assess the quality of evidence. Main results We included 22 RCTs: 12 trials from child day-care centres or schools in mainly high-income countries (54,006 participants), nine community-based trials in LMICs (15,303 participants), and one hospital-based trial among people with acquired immune deficiency

  2. Hand washing promotion for preventing diarrhoea.

    Science.gov (United States)

    Ejemot-Nwadiaro, Regina I; Ehiri, John E; Arikpo, Dachi; Meremikwu, Martin M; Critchley, Julia A

    2015-09-03

    Diarrhoea accounts for 1.8 million deaths in children in low- and middle-income countries (LMICs). One of the identified strategies to prevent diarrhoea is hand washing. To assess the effects of hand washing promotion interventions on diarrhoeal episodes in children and adults. We searched the Cochrane Infectious Diseases Group Specialized Register (27 May 2015); CENTRAL (published in the Cochrane Library 2015, Issue 5); MEDLINE (1966 to 27 May 2015); EMBASE (1974 to 27 May 2015); LILACS (1982 to 27 May 2015); PsycINFO (1967 to 27 May 2015); Science Citation Index and Social Science Citation Index (1981 to 27 May 2015); ERIC (1966 to 27 May 2015); SPECTR (2000 to 27 May 2015); Bibliomap (1990 to 27 May 2015); RoRe, The Grey Literature (2002 to 27 May 2015); World Health Organization (WHO) International Clinical Trial Registry Platform (ICTRP), metaRegister of Controlled Trials (mRCT), and reference lists of articles up to 27 May 2015. We also contacted researchers and organizations in the field. Individually randomized controlled trials (RCTs) and cluster-RCTs that compared the effects of hand washing interventions on diarrhoea episodes in children and adults with no intervention. Three review authors independently assessed trial eligibility, extracted data, and assessed risk of bias. We stratified the analyses for child day-care centres or schools, community, and hospital-based settings. Where appropriate, incidence rate ratios (IRR) were pooled using the generic inverse variance method and random-effects model with 95% confidence intervals (CIs). We used the GRADE approach to assess the quality of evidence. We included 22 RCTs: 12 trials from child day-care centres or schools in mainly high-income countries (54,006 participants), nine community-based trials in LMICs (15,303 participants), and one hospital-based trial among people with acquired immune deficiency syndrome (AIDS) (148 participants).Hand washing promotion (education activities, sometimes with

  3. Hand washing practices amongst medical students in Port Harcourt ...

    African Journals Online (AJOL)

    Nigerian Health Journal ... Rates of hand washing are low world wide even amongst health care workers who are should know about its importance. The aim of ... The greatest motivation for hand washing was fear of contracting disease, whilst ...

  4. Bacteriological aspects of hand washing: A key for health promotion and infections control

    Directory of Open Access Journals (Sweden)

    Ramezan Ali Ataee

    2017-01-01

    Full Text Available The aim of this review is to show the historical aspects of hands washing for healthy life and explains how can reduce the transmission of community-acquired infectious agents by healthcare workers and patients. This review article is prepared based on available database. The key words used were hands washing, risk assessment, hands hygiene, bacterial flora, contamination, infection, nosocomial, tap water, sanitizer, bacterial resistance, hands bacterial flora, washing methods, antiseptics, healthcare workers, healthcare personnel, from PubMed, ScienceDirect, Embase, Scopus, Web of Sciences, and Google Scholar. Data were descriptively analyzed. The insistence on hand washing has a history of 1400 years. The research results indicate that the bacteria released from the female washed hands in wet and dry condition was lower than from the male′s hands with a significance level (3 CFU vs. 8 CFU; confidence interval 95%, P ≤ 0.001. The valuable results of the study indicated that released amount of bacterial flora from wet hands is more than 10 times in compared to dry hands. In addition, established monitoring systems for washing hands before and after patient′s manipulation as well as after toilet were dominant indices to prevent the transfer of infectious agents to the patients. Increasing awareness and belief of the healthcare workers have shown an important role by about 30% reduction in the transfection. Hand washing could reduce the episodes of transmission of infectious agents in both community and healthcare settings. However, hand washing is an important key factor to prevent transmission of infectious agents to patients. There is no standard method for measuring compliance. Thus, permanent monitoring of hand washing to reduce the transmission of infections is crucial. Finally, the personnel must believe that hand washing is an inevitable approach to infection control.

  5. Hand Washing Practices and Compliance among Health Care ...

    African Journals Online (AJOL)

    Hand washing is the simplest, most inexpensive and most effective method of reducing the incidence of hospital-acquired infections in the Intensive Care Unit. Several reports have shown a relationship between improved hand washing practices and reduced infection rates. We conducted a prospective, ...

  6. Why Is Hand Washing So Important? (For Parents)

    Science.gov (United States)

    ... hand washing a rule for everyone, especially: before eating and cooking after using the bathroom after cleaning around the house after touching animals, including family pets before and after visiting or ...

  7. Effectiveness of a nonrinse, alcohol-free antiseptic hand wash.

    Science.gov (United States)

    Moadab, A; Rupley, K F; Wadhams, P

    2001-06-01

    This study evaluated the efficacy of a novel surfactant, allantoin, and benzalkonium chloride hand sanitizer using the US Food and Drug Administration's method for testing antiseptic hand washes that podiatric physicians and other health-care personnel use. The alcohol-free product, HandClens, was compared with an alcohol-based product, Purell. Independent researchers from the California College of Podiatric Medicine conducted the study using 40 volunteer students from the class of 2001. The results show that HandClens outperformed Purell and met the regulatory requirements for a hand sanitizer. Purell failed as an antimicrobial hand wash and was less effective than a control soap used in the study.

  8. Hand washing practices amongst medical students in Port Harcourt ...

    African Journals Online (AJOL)

    Alasia Datonye

    Background: Hand washing with soap and water is one of ... Method: This was a descriptive cross sectional survey ... simple questionnaire exploring perceptions, attitudes and ... Many studies have shown that doctors decontaminating their hands between seeing patients ..... countries: a systematic review and meta analysis.

  9. Hand washing practices and the occurrence of enteropathogenic ...

    African Journals Online (AJOL)

    ... levels of compliance to hand washing and related this to the occurrence of infectious bacteria in the test population. A questionnaire which contained information on bio-demographic characteristics and hand hygiene practices was applied to 100 individuals in the study population. Microbiological samples were obtained, ...

  10. Hand washing frequencies and procedures used in retail food services.

    Science.gov (United States)

    Strohbehn, Catherine; Sneed, Jeannie; Paez, Paola; Meyer, Janell

    2008-08-01

    Transmission of viruses, bacteria, and parasites to food by way of improperly washed hands is a major contributing factor in the spread of foodborne illnesses. Field observers have assessed compliance with hand washing regulations, yet few studies have included consideration of frequency and methods used by sectors of the food service industry or have included benchmarks for hand washing. Five 3-h observation periods of employee (n = 80) hand washing behaviors during menu production, service, and cleaning were conducted in 16 food service operations for a total of 240 h of direct observation. Four operations from each of four sectors of the retail food service industry participated in the study: assisted living for the elderly, childcare, restaurants, and schools. A validated observation form, based on 2005 Food Code guidelines, was used by two trained researchers. Researchers noted when hands should have been washed, when hands were washed, and how hands were washed. Overall compliance with Food Code recommendations for frequency during production, service, and cleaning phases ranged from 5% in restaurants to 33% in assisted living facilities. Procedural compliance rates also were low. Proposed benchmarks for the number of times hand washing should occur by each employee for each sector of food service during each phase of operation are seven times per hour for assisted living, nine times per hour for childcare, 29 times per hour for restaurants, and 11 times per hour for schools. These benchmarks are high, especially for restaurant employees. Implementation would mean lost productivity and potential for dermatitis; thus, active managerial control over work assignments is needed. These benchmarks can be used for training and to guide employee hand washing behaviors.

  11. Hand Washing Practices Among Emergency Medical Services Providers

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    Joshua Bucher

    2015-10-01

    Full Text Available Introduction: Hand hygiene is an important component of infection control efforts. Our primary and secondary goals were to determine the reported rates of hand washing and stethoscope cleaning in emergency medical services (EMS workers, respectively. Methods: We designed a survey about hand hygiene practices. The survey was distributed to various national EMS organizations through e-mail. Descriptive statistics were calculated for survey items (responses on a Likert scale and subpopulations of survey respondents to identify relationships between variables. We used analysis of variance to test differences in means between the subgroups. Results: There were 1,494 responses. Overall, reported hand hygiene practices were poor among pre-hospital providers in all clinical situations. Women reported that they washed their hands more frequently than men overall, although the differences were unlikely to be clinically significant. Hygiene after invasive procedures was reported to be poor. The presence of available hand sanitizer in the ambulance did not improve reported hygiene rates but improved reported rates of cleaning the stethoscope (absolute difference 0.4, p=0.0003. Providers who brought their own sanitizer were more likely to clean their hands. Conclusion: Reported hand hygiene is poor amongst pre-hospital providers. There is a need for future intervention to improve reported performance in pre-hospital provider hand washing.

  12. Hand Washing Practices Among Emergency Medical Services Providers.

    Science.gov (United States)

    Bucher, Joshua; Donovan, Colleen; Ohman-Strickland, Pamela; McCoy, Jonathan

    2015-09-01

    Hand hygiene is an important component of infection control efforts. Our primary and secondary goals were to determine the reported rates of hand washing and stethoscope cleaning in emergency medical services (EMS) workers, respectively. We designed a survey about hand hygiene practices. The survey was distributed to various national EMS organizations through e-mail. Descriptive statistics were calculated for survey items (responses on a Likert scale) and subpopulations of survey respondents to identify relationships between variables. We used analysis of variance to test differences in means between the subgroups. There were 1,494 responses. Overall, reported hand hygiene practices were poor among pre-hospital providers in all clinical situations. Women reported that they washed their hands more frequently than men overall, although the differences were unlikely to be clinically significant. Hygiene after invasive procedures was reported to be poor. The presence of available hand sanitizer in the ambulance did not improve reported hygiene rates but improved reported rates of cleaning the stethoscope (absolute difference 0.4, p=0.0003). Providers who brought their own sanitizer were more likely to clean their hands. Reported hand hygiene is poor amongst pre-hospital providers. There is a need for future intervention to improve reported performance in pre-hospital provider hand washing.

  13. Hand washing in operating room: a procedural comparison

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    Alessia Stilo

    2016-09-01

    Full Text Available BACKGROUND Hand washing has been considered a measure of personal hygiene for centuries and it is known that an improper hand hygiene by healthcare workers is responsible for about 40% of nosocomial infections. Therefore, surgical hand preparation is a critical element for healthcare safety in order to reduce microbial contamination of  surgical wound in case of non detected break of the gloves. The aim of our study is to evaluate the efficacy three antiseptics: Povi-iodine scrub; EPG (Ethanol, Hydrogen Peroxide, Glycerol, recommended by WHO, and common marseille soap type in a liquid formulation. METHODS It was designed a randomized, double-blind, single-center study conducted in the University Hospital of Messina, from January to June 2013. We asked operators to put the fingertips of their right hand (if not left-handed for one minute on the PCA medium, before washing with the three types of antiseptics, and after washing and drying. Drying was made using sterile gauzes or disposable wipes. Then, we measured the number of colony forming units per mL (CFU/mL and calculated the percentage of microbial load reduction. RESULTS 211 samples have been considered for statistical analysis: in 42 samples, in fact, initial microbial load was lower than after washing. Washing with EPG reduced CFU/ml from  a mean of 38,9 to 4,1 (86,5% reduction, washing with povi-iodine scrub from 59,55 to 12,9 (75,9% reduction and washing with Marseille soap from 47,26 to 12,7 (64,3% reduction. CONCLUSIONS Our study shows that washing with EPG has superior efficacy in CFU reduction. Antiseptic hand washing, however, cannot be considered the only measure to reduce infections: the anomaly of some results (initial microbial load lower than after washing  demonstrates that drying is an essential phase in the presurgical preparation. Therefore, hand hygiene must be part of a more complex strategy of surveillance and control of nosocomial infections

  14. Patients' Hand Washing and Reducing Hospital-Acquired Infection.

    Science.gov (United States)

    Haverstick, Stacy; Goodrich, Cara; Freeman, Regi; James, Shandra; Kullar, Rajkiran; Ahrens, Melissa

    2017-06-01

    Hand hygiene is important to prevent hospital-acquired infections. Patients' hand hygiene is just as important as hospital workers' hand hygiene. Hospital-acquired infection rates remain a concern across health centers. To improve patients' hand hygiene through the promotion and use of hand washing with soap and water, hand sanitizer, or both and improve patients' education to reduce hospital-acquired infections. In August 2013, patients in a cardiothoracic postsurgical step-down unit were provided with individual bottles of hand sanitizer. Nurses and nursing technicians provided hand hygiene education to each patient. Patients completed a 6-question survey before the intervention, at hospital discharge and 1, 2, and 3 months after the intervention. Hospital-acquired infection data were tracked monthly by infection prevention staff. Significant correlations were found between hand hygiene and rates of infection with vancomycin-resistant enterococci ( P = .003) and methicillin-resistant Staphylococcus aureus ( P = .01) after the intervention. After the implementation of hand hygiene interventions, rates of both infections declined significantly and patients reported more staff offering opportunities for and encouraging hand hygiene. This quality improvement project demonstrates that increased hand hygiene compliance by patients can influence infection rates in an adult cardiothoracic step-down unit. The decreased infection rates and increased compliance with hand hygiene among the patients may be attributed to the implementation of patient education and the increased accessibility and use of hand sanitizer. ©2017 American Association of Critical-Care Nurses.

  15. [Microbiological characteristics of selected liquid soaps for hands washing].

    Science.gov (United States)

    Tyski, Stefan; Bocian, Ewa; Zawistowska, Anna; Mrówka, Agnieszka; Kruszewska, Hanna; Grzybowska, Wanda; Zareba, Tomasz

    2013-01-01

    According to common belief, supported by the authority of the World Health Organization - WHO, the common (social) hand washing is the simplest, cheapest and the most effective way of reduction the hospital-acquired infections. For this purpose products of"liquid soaps", present in a large number on the market, are most often applied. Microbiological status (microbiological purity and antimicrobial activity) of"liquid soaps" available on the Polish market is not known, because relevant routinely studies have not been performed. Only the antibacterial and / or antifungal activity of certain formulations is sometimes assessed, especially when the manufacturer suggests the standardized application of the products for surgical or hygienic procedures. The aim of this study was to determine the microbiological quality, especially microbiological purity and antimicrobial activity of the selected hands washing products, presents on the Polish market. The 12 selected commercial products, available on the market in Poland, dedicated for hands washing were included into study. Microbiological purity test was carried out in accordance with the Polish Pharmacopoeia (FP) monograph (FP monograph numbers correspond to numbers of the European Pharmacopoeia monograph- Ph. Eur.) No 2.6.12 "Microbiological examination of non-sterile products: microbial enumaration tests", and the monograph of FP No. 2.6.13 "Microbiological examination of non-sterile products: test for specified microorganisms". The following physico-chemical properties of soaps were examined: the pH of the formulations was measured according to the monograph FP No. 2.2.3. "Potentiometric determination of pH", the density of products was assayed according to the monograph FPNo. 2.2.5. "Relative density" and determination the water activity was performed by monograph FP No 2.9.39 "Water-solid interactions: determination of sorption-desorption isotherms and of water activity". Next, antibacterial and antifungal

  16. Mothers’ Hand washing Practice and Diarrhea Cases in Children under Five in Baleendah, Bandung

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    M Syafril Firdaus

    2015-06-01

    Full Text Available ackground: Diarrhea is a disease, especially in children, with high mortality and morbidity rate in developing countries, including Indonesia. Diarrhea can be prevented if people can apply clean and healthy behaviors, especially hand washing. Hand washing is the cheapest, simplest, and the most effective methods for prevention of diarrhea. The objective of this study is to identify the knowledge, attitude, and practice of mothers’ hand washing and diarrhea cases in children under five in Baleendah District, Bandung. Methods: A descriptive study was conducted during September−November 2012 to 210 mothers who had children (ages 12−59 months in Baleendah using rapid survey technique. The time allocated for each village was adjusted to the population proportion for each region. The data were analyzed using computer and was represented using frequency distribution. Results: This study showed that the respondents had good level of knowledge and attitude of hand washing (83.8% and 61%, respectively, but only 21% of the respondents’ practices of hand washing was in good level. Most of the respondents did not wash their hands according to the 7 steps of correct hand washing. Moreover the percentage of children with diarrhea in Baleendah was 43.8% (92 cases during the study. Conclusions: There should be dissemination of information about the benefit of washing hands with 7 steps of correct hands washing so that families can practice it and can prevent diarrhea in children under five.

  17. Social determinants of good hand-washing practice (GHP) among adolescents in a rural Indian community.

    Science.gov (United States)

    Dobe, Madhumita; Mandal, Ram Narayan; Jha, Ayan

    2013-01-01

    A cross-sectional study was conducted in 5 randomly selected villages to assess prevalence of good hand-washing practice (GHP) among adolescents, and describe the social determinants. The prevalence of adolescent GHP was 32.1% (95% CI = 27.1, 37.1). Logistic regression established 5 significant positive predictors-maternal GHP, presence of sanitary latrine, availability of soap at hand-washing locations, in-house water supply, and higher per capita income. Our research provides a scope for better understanding of the socioeconomic determinants of GHP in a rural Indian setting, and may find implications in the Total Sanitation Campaign launched by Government of India.

  18. Effect of health education on hand washing of mothers of under five ...

    African Journals Online (AJOL)

    Diarrhea is a leading cause of morbidity and mortality in children under five years of age in middle and low income countries. Nearly one in five child deaths is due to diarrhea and globally it accounts for 1.5million deaths annually. Although hand washing with soap is effective for the prevention of transmission of diarrhea ...

  19. Inspections of Hand Washing Supplies and Hand Sanitizer in Public Schools

    Science.gov (United States)

    Ramos, Mary M.; Blea, Mary; Trujillo, Rebecca; Greenberg, Cynthia

    2010-01-01

    Hand washing and hand antisepsis are proven infection control measures in the school setting, yet barriers such as lack of soap, paper towels, and hand sanitizer can hinder compliance. This pilot study measured the prevalence of hand cleaning supplies in public schools. Ten school districts (93 schools) participated in school nurse inspections. In…

  20. Proper Hand-Washing Techniques in Public Restrooms: Differences in Gender, Race, Signage, and Time of Day

    Science.gov (United States)

    Kinnison, Andrea; Cottrell, Randal R.; King, Keith A.

    2004-01-01

    The purpose of this study was to evaluate hand washing behaviors in public restrooms with and without reminder signs. Gender, race, signage, and time of day were examined to determine if there were differences in hand washing compliance based on these variables. Participants included male and female adults entering restrooms at two public shopping…

  1. Arbi Care application increases preschool children's hand-washing self-efficacy among preschool children.

    Science.gov (United States)

    Arbianingsih; Utario, Yossy; Rustina, Yeni; Krianto, Tri; Ayubi, Dian

    2018-02-01

    This research aimed to examine the effectiveness of an Android mobile game application called Arbi Care as a means to prevent diarrhea and build self-efficacy in hand washing among preschool children. This research used a pre- and post-test control group and time series design approach. Respondents were chosen randomly from a group of four to six years children. The intervention group (n = 60) received Arbi Care intervention for 25 minutes, twice a week, for five weeks while the control group (n = 60) received standard education. Self-efficacy was measured by using questionnaire and observation. Measurement was carried out three times in the sixth, eight, and tenth week post-intervention. The data was analyzed using the GLMRM test. There was a significant increase in the average score of self-efficacy in hand washing for the intervention group versus the control group. Moreover, there were significant differences in the results of average scores in which the intervention group showed much better self-efficacy improvement over the control group during the first, second, and final post-test after the intervention was given (p Android-based educational game can be an effective medium to improve hand washing self-efficacy among preschool children, thus helping to prevent diarrhea. Copyright © 2018 Elsevier España, S.L.U. All rights reserved.

  2. Extending the Theory of Normative Social Behavior to Predict Hand-Washing among Koreans.

    Science.gov (United States)

    Chung, Minwoong; Lapinski, Maria Knight

    2018-04-10

    The current study tests the predictions of the theory of normative social behavior (TNSB) in a hand-washing context in a Korean sample and extends the theory to examine the role of perceived publicness, a variable believed to activate face concerns, as a moderator of the norm-behavior relationship. The findings show substantial main effects for all of the study variables on behavior. In addition, the descriptive norm-behavior relationship is moderated by perceived publicness and outcome expectations, but the nature of the interactions is not consistent with that evidenced in previous literature on US samples. Implications for normative theory and communication campaigns are discussed.

  3. Exploring the gap between hand washing knowledge and practices in Bangladesh: a cross-sectional comparative study.

    Science.gov (United States)

    Rabbi, Sifat E; Dey, Nepal C

    2013-01-30

    Hand washing is considered as one of the most effective hygiene promotion activities for public health in developing countries. This study compared hand washing knowledge and practices in BRAC's water; sanitation and hygiene (WASH) programme areas over time. This study is a cross-sectional comparative study between baseline (2006), midline (2009) and end-line (2011) surveys in 50 sub-districts from the first phase of the programme. Thirty thousand households from 50 sub-districts were selected in two steps: i) 30 villages were selected from each sub-district by cluster sampling, and ii) 20 households were chosen systematically from each village. The matched households were considered (26,404 in each survey) for analysis. Data were collected from households through face-to-face interview using a pre-tested questionnaire. Respondents were the adult female members of the same households, who had knowledge of day-to-day household activities related to water, sanitation and hygiene. A gap between perception and practice of proper hand washing practices with soap was identified in the study areas. Hand washing practice with soap before eating was much lower than after defecation. In baseline data, 8% reported to wash their hands with soap which significantly increased to 22% in end line. Hand washing knowledge and practices before cooking food, before serving food and while handling babies is considerably limited than other critical times. A multivariate analysis shows that socio-economic factors including education of household head and respondent, water availability and access to media have strong positive association with hand washing with soap. Gap between knowledge and practice still persists in hand washing practices. Long term and extensive initiatives can aware people about the effectiveness of hand washing.

  4. Exploring the gap between hand washing knowledge and practices in Bangladesh: a cross-sectional comparative study

    Directory of Open Access Journals (Sweden)

    Rabbi Sifat E

    2013-01-01

    Full Text Available Abstract Background Hand washing is considered as one of the most effective hygiene promotion activities for public health in developing countries. This study compared hand washing knowledge and practices in BRAC’s water; sanitation and hygiene (WASH programme areas over time. Methods This study is a cross-sectional comparative study between baseline (2006, midline (2009 and end-line (2011 surveys in 50 sub-districts from the first phase of the programme. Thirty thousand households from 50 sub-districts were selected in two steps: i 30 villages were selected from each sub-district by cluster sampling, and ii 20 households were chosen systematically from each village. The matched households were considered (26,404 in each survey for analysis. Data were collected from households through face-to-face interview using a pre-tested questionnaire. Respondents were the adult female members of the same households, who had knowledge of day-to-day household activities related to water, sanitation and hygiene. Results A gap between perception and practice of proper hand washing practices with soap was identified in the study areas. Hand washing practice with soap before eating was much lower than after defecation. In baseline data, 8% reported to wash their hands with soap which significantly increased to 22% in end line. Hand washing knowledge and practices before cooking food, before serving food and while handling babies is considerably limited than other critical times. A multivariate analysis shows that socio-economic factors including education of household head and respondent, water availability and access to media have strong positive association with hand washing with soap. Conclusion Gap between knowledge and practice still persists in hand washing practices. Long term and extensive initiatives can aware people about the effectiveness of hand washing.

  5. The effect of Ebola Virus Disease outbreak on hand washing among secondary school students in Ondo State Nigeria, October, 2014.

    Science.gov (United States)

    Ilesanmi, Olayinka Stephen; Alele, Faith Osaretin

    2015-01-01

    Hand washing with soap and water is one of the cheapest, most effective ways of limiting the spread of Ebola Virus Disease (EVD). Despite its importance the prevalence of hand washing was low before the EVD outbreak in Nigeria. This study aimed at determining the factors associated with improved hand washing practices following the EVD outbreak. A descriptive cross sectional study of 440 students from a secondary school in Owo, Ondo State was done. Data was collected in October 2014 when Nigeria was yet to be declared EVD free. Systematic random sampling was used. A semi-structured, interviewer administered questionnaire was used. Data was analysed with epi info version 7, descriptive statistics were done, Chi square test was used for the assessment of significant associations between proportions. Determinants of good hand washing practices was identified using logistics regression analysis at 5% level of significance. Of 440 respondents, mean age was 13.7±1.9 years. Females were 48.2%. Only 4.6% have never heard of Ebola Virus Disease.Level of hand washing with soap and water improved by62.6%. Significant improvement in hand washing was in 75.8% of those who heard through social media (p Newspaper readers(p schools.

  6. Interventions to improve the compliance of health care professionals to hand washing: an integrative review

    Directory of Open Access Journals (Sweden)

    Adriana Cristina de Oliveira

    2013-12-01

    Full Text Available The objective of this study was to identify the main strategies used to improve the compliance of health care professionals to hand washing. This is an integrative literature review, which search included journals in English, Spanish and Portuguese. Twenty—three articles were included. An electronic tool was developed on Microsoft Office Excel and the main results were submitted to descriptive analysis. Of the total studies, 87.1% had before and after designs and several methods were used to monitor compliance rate (direct observation, supply use and self-reported rates. Multimodal interventions were used in 87.0%, and the most often employed were: education, feedback, alcohol being available and posters. The largest challenge identified was not only improving the compliance rates to hand washing, but, most of all, keeping them high. It was observed there is a need to use multimodal strategies that contribute to behavior change considering the local setting. Descriptors: Hand Disinfection; Health Personnel; Cross Infection; Nursing.

  7. Design, development and transfer of a sanitation hand-washing dispenser to rural areas in South Africa

    CSIR Research Space (South Africa)

    Wilkinson, M

    2006-02-01

    Full Text Available was ranked fifth in the list of causes of premature mortality in South Africa in 2000 and is also a major cause of death among children under the age of five. All sanitation programmes and interventions in South Africa focus some attention on hand- washing...

  8. Use of a patient hand hygiene protocol to reduce hospital-acquired infections and improve nurses' hand washing.

    Science.gov (United States)

    Fox, Cherie; Wavra, Teresa; Drake, Diane Ash; Mulligan, Debbie; Bennett, Yvonne Pacheco; Nelson, Carla; Kirkwood, Peggy; Jones, Louise; Bader, Mary Kay

    2015-05-01

    Critically ill patients are at marked risk of hospital-acquired infections, which increase patients' morbidity and mortality. Registered nurses are the main health care providers of physical care, including hygiene to reduce and prevent hospital-acquired infections, for hospitalized critically ill patients. To investigate a new patient hand hygiene protocol designed to reduce hospital-acquired infection rates and improve nurses' hand-washing compliance in an intensive care unit. A preexperimental study design was used to compare 12-month rates of 2 common hospital-acquired infections, central catheter-associated bloodstream infection and catheter-associated urinary tract infection, and nurses' hand-washing compliance measured before and during use of the protocol. Reductions in 12-month infection rates were reported for both types of infections, but neither reduction was statistically significant. Mean 12-month nurse hand-washing compliance also improved, but not significantly. A hand hygiene protocol for patients in the intensive care unit was associated with reductions in hospital-acquired infections and improvements in nurses' hand-washing compliance. Prevention of such infections requires continuous quality improvement efforts to monitor lasting effectiveness as well as investigation of strategies to eliminate these infections. ©2015 American Association of Critical-Care Nurses.

  9. Regular use of a hand cream can attenuate skin dryness and roughness caused by frequent hand washing

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    Kampf Günter

    2006-02-01

    Full Text Available Abstract Background Aim of the study was to determine the effect of the regular use of a hand cream after washing hands on skin hydration and skin roughness. Methods Twenty-five subjects washed hands and forearms with a neutral soap four times per day, for 2 minutes each time, for a total of two weeks. One part of them used a hand cream after each hand wash, the others did not (cross over design after a wash out period of two weeks. Skin roughness and skin hydration were determined on the forearms on days 2, 7, 9 and 14. For skin roughness, twelve silicon imprint per subject and time point were taken from the stratum corneum and assessed with a 3D skin analyzer for depth of the skin relief. For skin hydration, five measurements per subject and time point were taken with a corneometer. Results Washing hands lead to a gradual increase of skin roughness from 100 (baseline to a maximum of 108.5 after 9 days. Use of a hand cream after each hand wash entailed a decrease of skin roughness which the lowest means after 2 (94.5 and 14 days (94.8. Skin hydration was gradually decreased after washing hands from 79 (baseline to 65.5 after 14 days. The hand wash, followed by use of a hand cream, still decreased skin hydration after 2 days (76.1. Over the next 12 days, however, skin hydration did not change significantly (75.6 after 14 days. Conclusion Repetitive and frequent hand washing increases skin dryness and roughness. Use of a hand cream immediately after each hand wash can confine both skin dryness and skin roughness. Regular use of skin care preparations should therefore help to prevent both dry and rough skin among healthcare workers in clinical practice.

  10. Impact of regular soap provision to primary schools on hand washing and E. coli hand contamination among pupils in Nyanza Province, Kenya: a cluster-randomized trial.

    Science.gov (United States)

    Saboori, Shadi; Greene, Leslie E; Moe, Christine L; Freeman, Matthew C; Caruso, Bethany A; Akoko, Daniel; Rheingans, Richard D

    2013-10-01

    We assessed whether supplying soap to primary schools on a regular basis increased pupil hand washing and decreased Escherichia coli hand contamination. Multiple rounds of structured observations of hand washing events after latrine use were conducted in 60 Kenyan schools, and hand rinse samples were collected one time in a subset of schools. The proportion of pupils observed practicing hand washing with soap (HWWS) events was significantly higher in schools that received a soap provision intervention (32%) and schools that received soap and latrine cleaning materials (38%) compared with controls (3%). Girls and boys had similar hand washing rates. There were non-significant reductions in E. coli contamination among intervention school pupils compared with controls. Removing the barrier of soap procurement can significantly increase availability of soap and hand washing among pupils; however, we discuss limitations in the enabling policy and institutional environment that may have prevented reaching desired levels of HWWS.

  11. Knowledge, Attitude and Practice of Hand washing among Street vendors in Campus of Universitas Padjadjaran, West Java from June-November 2012

    Directory of Open Access Journals (Sweden)

    Tajul Al Adib

    2015-09-01

    Full Text Available Background: Hand washing is a moderate step in preventing communicable diseases. Communicable diseases like diarrhea and respiratory tract infection can be reduced significantly just by practicing hand washing. Most of the people already knew how to wash their hand, but some of them still did not understand the objective and the correct ways of performing hand washing. The aim of the study was to evaluate knowledge, attitude and practice of hand washing among street vendors. Methods: A descriptive study was conducted to 30 street vendors at the gate of Universitas Padjadjaran Campus from June to November 2012. The inclusion criterias were street vendors involved in food preparation, cooking, mixing, and willing to participate in this study. A questionnaire was developed to identify the knowledge, attitude and practice of hand washing. The level of the variable measured was divided into 3 categories: good, moderate, and poor. The collected data were analyzed and presented in table. Results: There were 12/30 of street vendors classified as having moderate knowledge and 25/30 as having good attitude and good practice of hand washing. Conclusions: The street vendors at the gate of Universitas Padjadjaran Campus had moderate knowledge, good attitude and good practice of hand washing.

  12. Efficacy of Moringa oleifera leaf powder as a hand-washing product: a crossover controlled study among healthy volunteers.

    Science.gov (United States)

    Torondel, Belen; Opare, David; Brandberg, Bjorn; Cobb, Emma; Cairncross, Sandy

    2014-02-14

    Moringa oleifera is a plant found in many tropical and subtropical countries. Many different uses and properties have been attributed to this plant, mainly as a nutritional supplement and as a water purifier. Its antibacterial activity against different pathogens has been described in different in vitro settings. However the potential effect of this plant leaf as a hand washing product has never been studied. The aim of this study is to test the efficacy of this product using an in vivo design with healthy volunteers. The hands of fifteen volunteers were artificially contaminated with Escherichia coli. Moringa oleifera leaf powder was tested as a hand washing product and was compared with reference non-medicated liquid soap using a cross over design following an adaptation of the European Committee for Standardization protocol (EN 1499). In a second part of tests, the efficacy of the established amount of Moringa oleifera leaf powder was compared with an inert powder using the same protocol. Application of 2 and 3 g of dried Moringa oleifera leaf powder (mean log10-reduction: 2.44 ± 0.41 and 2.58 ± 0.34, respectively) was significantly less effective than the reference soap (3.00 ± 0.27 and 2.99 ± 0.26, respectively; p Moringa oleifera (2 and 3 g) but using a wet preparation, was also significantly less effective than reference soap (p Moringa oleifera powder in dried or wet preparation (mean log10-reduction: 2.70 ± 0.27 and 2.91 ± 0.11, respectively) compared with reference soap (2.97 ± 0.28). Application of calcium sulphate inert powder was significantly less effective than the 4 g of Moringa oleifera powder (p Moringa oleifera powder in dried and wet application had the same effect as non-medicated soap when used for hand washing. Efficacious and available hand washing products could be useful in developing countries in controlling pathogenic organisms that are transmitted through contaminated hands.

  13. No germs on me: a social marketing campaign to promote hand-washing with soap in remote Australian Aboriginal communities.

    Science.gov (United States)

    McDonald, Elizabeth; Slavin, Nicola; Bailie, Ross; Schobben, Xavier

    2011-03-01

    A social marketing campaign promoting hand-washing with soap was implemented to reduce the high burden of infection experienced by Australian Aboriginal children living in remote communities. Epidemiological evidence of effect and other evidence were used to identify the hygiene intervention and health promotion approach for the project. We drew on the findings of: (i) a systematic literature review to identify the intervention for which there is strong effect in similar populations and contexts; and (ii) a narrative literature review to determine our health promotion approach. This process provided practitioners with confidence and understanding so they could address a complex problem in a politically and otherwise sensitive context.

  14. Testing biological effects of hand-washing grey water for reuse in irrigation on an urban farm: a case study.

    Science.gov (United States)

    Khan, Mohammad Zain; Sim, Yei Lin; Lin, Yang Jian; Lai, Ka Man

    2013-01-01

    The feasibility of reusing hand-washing grey water contaminated with antibacterial hand-washing liquid for irrigation purposes in an urban farm is explored in this case study. Experiments are carried out to investigate if the quality of this grey water allows for its reuse in agriculture as per the guidelines established by the World Health Organization (WHO). However, there is no guideline to test the biological effect of grey water prior to agricultural use. It is plausible that the antibacterial property of the grey water can harm the soil microbial system and plants when applied to land, even if all other water quality parameters satisfy the WHO limit. We use algae (Chlorella vulgaris) and indigenous soil bacteria as initial plant and soil bacteria indicators, respectively, to test the potential inhibition of the water on plants and soil bacteria. Results show that the chemical oxygen demand (COD) of the grey water is 10% higher than the WHO permissible level, while all other water quality parameters are within the limits after four days of our experimental period. An inhibitory effect is observed in all of the biological tests. However, the inhibitory effect on algae and soil bacteria is not observed after the four-day period. The case study demonstrates a new approach for testing the biological effect of grey water, which can be used in conjunction with the WHO guideline, and provides data for this urban farm to set up a future water treatment system for grey-water reuse in irrigation.

  15. Use of Electronic Loggers to Measure Changes in the Rates of Hand Washing with Soap in Low-Income Urban Households in India.

    Science.gov (United States)

    Wright, Richard L; Zillmer, Ruediger; Biran, Adam; Hall, Peter; Sidibe, Myriam

    2015-01-01

    We evaluated the utility of electronic loggers to measure the effects of a simple intervention designed to influence the rates of hand washing with soap within enclosed toilets and bathrooms in low-income urban households in Kerala, India. 58 households were given three items with embedded electronic loggers for a period of 2-5 days. Two logged soaps tracked hand and body washing in the bathroom. The third logged item was a water vessel used for flushing the toilet and for post-defecation anal cleansing; this served as a marker of toilet use. In addition, 28 households in a Soap by toilet arm were given an additional logged soap, to be kept by the toilet, and used for hand washing. Compared with the Soap in bathroom arm, the loggers in the Soap by toilet households recorded 73% greater daily use of soaps designated for hand washing (t(36)=2.92, psoap and changes in hand washing with soap after use of the toilet. Further adoption of logger technologies would enable more insightful studies of hand washing within urban environments.

  16. Single treatment with ethanol hand rub is ineffective against human rhinovirus--hand washing with soap and water removes the virus efficiently.

    Science.gov (United States)

    Savolainen-Kopra, Carita; Korpela, Terttu; Simonen-Tikka, Marja-Leena; Amiryousefi, Ali; Ziegler, Thedi; Roivainen, Merja; Hovi, Tapani

    2012-03-01

    Ethanol-containing hand rubs are used frequently as a substitute for hand washing with water and soap. However, not all viruses are inactivated by a short term rubbing with alcohol. The capacity of a single round of instructed and controlled hand cleaning with water and soap or ethanol-containing hand rub, respectively, was tested for removal of human rhinovirus administered onto the skin of healthy volunteers on the back of the hands. Hand washing with soap and water appeared to be much more efficient for removing rhinoviruses from skin than rubbing hands with an ethanol-containing disinfectant. After washing with soap and water the virus was detected in 3/9 (33.3%) test persons from the left hand and 1/9 (11.1%) cases from the right hand, whereas the virus was detected invariably by real-time RT-PCR from both hands after cleaning with alcohol hand rub (P-value soap can clean efficiently hands contaminated with the virus responsible for an extensive share of common cold episodes. Copyright © 2012 Wiley Periodicals, Inc.

  17. Typhoid fever: hurdles to adequate hand washing for disease prevention among the population of a peri-urban informal settlement in Fiji.

    Science.gov (United States)

    Greenwell, James; McCool, Judith; Kool, Jacob; Salusalu, Mosese

    2013-01-01

    The Pacific island nation of Fiji Islands has high rates of endemic typhoid fever which is difficult to diagnose and often underreported. However, the majority of cases are preventable through use of safe water; adequate sanitation; vaccination; and, most sustainable of all, simple hygienic behaviour, such as hand washing with soap (HWWS). Despite many attempts by public health authorities, little progress has been made in the area of environmental adaptation and behaviour change. To explore perceptions of typhoid fever risk among urban squatters and behavioural determinants surrounding HWWS, indigenous Fijians living in informal settlements with high typhoid fever incidence were invited to participate in focus group discussions. In-depth interviews were conducted with community leaders. Perceptions of typhoid fever suggest confusion about risk factors, symptoms and communicability. Environmental barriers for hand washing were related to water and soap access. Standard social marketing approaches have been trialled with little clear evidence of impact. Despite this, we continue to advocate for the social and cultural determinants of typhoid prevention to remain central to future public health strategies. Despite behaviour change being notoriously difficult, we argue that community-driven behaviour adaptation initiatives based on sound epidemiological evidence and health communication theory are likely to have significant impact and greater likelihood of sustainability.

  18. Typhoid fever: hurdles to adequate hand washing for disease prevention among the population of a peri-urban informal settlement in Fiji

    Directory of Open Access Journals (Sweden)

    Mosese Salusalu

    2013-01-01

    Full Text Available Problem/context: The Pacific island nation of Fiji Islands has high rates of endemic typhoid fever which is difficult to diagnose and often underreported. However, the majority of cases are preventable through use of safe water; adequate sanitation; vaccination; and, most sustainable of all, simple hygienic behaviour, such as hand washing with soap (HWWS. Despite many attempts by public health authorities, little progress has been made in the area of environmental adaptation and behaviour change. Action: To explore perceptions of typhoid fever risk among urban squatters and behavioural determinants surrounding HWWS, indigenous Fijians living in informal settlements with high typhoid fever incidence were invited to participate in focus group discussions. In-depth interviews were conducted with community leaders. Outcome: Perceptions of typhoid fever suggest confusion about risk factors, symptoms and communicability. Environmental barriers for hand washing were related to water and soap access. Standard social marketing approaches have been trialled with little clear evidence of impact. Despite this, we continue to advocate for the social and cultural determinants of typhoid prevention to remain central to future public health strategies. Discussion: Despite behaviour change being notoriously difficult, we argue that community-driven behaviour adaptation initiatives based on sound epidemiological evidence and health communication theory are likely to have significant impact and greater likelihood of sustainability.

  19. Assessing the Health Impact of the following Measures in Schools in Maradi (Niger: Construction of Latrines, Clean Water Supply, Establishment of Hand Washing Stations, and Health Education

    Directory of Open Access Journals (Sweden)

    Halima Boubacar Maïnassara

    2014-01-01

    Full Text Available Objective. To assess the effect on health of the following measures in schools in Maradi (Niger: clean water supply, construction of latrines, establishment of hand washing stations, and health education. Methodology. It was a “before and after” intervention study on a sample of school children aged 7 to 12 years in the Maradi region. The interventions included building of latrines, supplying clean water, setting up hand washing stations, and teaching health education lessons. An individual questionnaire, analysis of stool samples, and a group questionnaire were administered to children and teachers, respectively. The threshold for significance was set at P<0.05. Results. A statistically significant reduction in cases of diarrhoea and abdominal pains was noted after the project. Overall, carriage of at least one parasite increased from 7.5% before the project to 10.2% after it (P=0.04. In the programme group schools, there was a statistically significant increase in the prevalence of Hymenolepis nana, from 0 to 1.9 (P=0.02. Pinworm prevalence remained stable in this group but increased significantly in the control group. Conclusions. Putting health infrastructure in place in schools obviously had an impact on hygiene-related habits in the beneficiary schools and communities.

  20. Bacterial contamination of the hands of food handlers as indicator of hand washing efficacy in some convenient food industries in South Africa.

    Science.gov (United States)

    Aa, Lambrechts; Is, Human; Jh, Doughari; Jfr, Lues

    2014-07-01

    Hands of ready-to-eat food service employees have been shown to be vectors in the spread of foodborne disease, mainly because of poor personal hygiene and accounting for approximately 97% of food borne illnesses in food service establishments and homes. Our objective was to evaluate the efficacy of hand washing practices and sanitation before commencing work among food handlers in the convenient food industry in Gauteng, South Africa. A total of 230 samples were collected, involving 100% of the food handlers, in 8 selected convenient food outlets with their main focus on preparing ready-to-eat foods. The workers' cleaned and disinfected dominant hands were sampled for Total Plate Count (TPC), Staphylococcus aureus and Escherichia coli. Bacteria were isolated and counted using standard methods. The highest bacterial count from the hand samples was 7.4 x 10(3) cfu.cm(-2) and the lowest showed no detectable growth. Although hands with a count of 0 cfu.cm(-2) were found in all of the plants, the results indicated that all the plants exceeded the legal limit for food surfaces or hands of food handlers had no bacteria detectable on their hands. One sample tested positive for E. coli and S. aureus could not be detected on the hands of any of the food handlers. The study revealed that hand hygiene is unsatisfactory and may have serious implications for public health due to contamination of food from food handlers' hands. This therefore underlined the importance of further training to improve food handlers' knowledge of good hand washing practices.

  1. Removal of Escherichia coli and Enterococcus faecalis after Hand Washing with Antimicrobial and Nonantimicrobial Soap and Persistence of These Bacteria in Rinsates.

    Science.gov (United States)

    Pérez-Garza, J; García, S; Heredia, N

    2017-10-01

    Food handlers are important sources of contamination in the agricultural environment. This study was conducted (i) to evaluate the activity of antimicrobial soaps against Escherichia coli and Enterococcus faecalis using a hand washing model with soiled hands and (ii) to determine the survival and persistence of these bacteria in rinsates. Sterilized agricultural soil from tomato and pepper farms was inoculated with E. coli or E. faecalis at 10 3 or 10 6 CFU/g. Decontaminated hands were placed in contact with contaminated soil for 2 min and were then washed with soaps with or without antimicrobial compounds (citric extracts, chloroxylenol, triclosan, or chlorhexidine gluconate). As the control, hands were washed with sterile distilled water. The levels of bacteria remaining on the hands and recovered from the rinsates were determined using a membrane filtration method and selective media. Antimicrobial soaps removed levels of E. coli similar to those removed by distilled water and nonantimicrobial soap on hands contaminated with E. coli at 10 3 CFU/g. However, when hands were contaminated with E. coli at 10 6 CFU/g, more E. coli was removed with the chlorhexidine gluconate soap. When hands were contaminated with E. faecalis at 10 3 CFU/g, bacteria were removed more effectively with soaps containing chloroxylenol or chlorhexidine gluconate. When hands were contaminated with E. faecalis at 10 6 CFU/g, all of the antimicrobial soaps were more effective for removing the bacteria than were distilled water and nonantimicrobial soap. E. coli grew in all of the hand washing rinsates except that containing triclosan, whereas E. faecalis from the 10 6 CFU/g treatments grew in rinsates containing chlorhexidine gluconate and in the distilled water rinsates. Washing with antimicrobial soap was more effective for reducing bacteria on soiled hands than was washing with water or nonantimicrobial soap. However, persistence or growth of bacteria in these rinsates poses health risks.

  2. Quantifying the effect of hand wash duration, soap use, ground beef debris, and drying methods on the removal of Enterobacter aerogenes on hands.

    Science.gov (United States)

    Jensen, Dane A; Danyluk, Michelle D; Harris, Linda J; Schaffner, Donald W

    2015-04-01

    Hand washing is recognized as a crucial step in preventing foodborne disease transmission by mitigating crosscontamination among hands, surfaces, and foods. This research was undertaken to establish the importance of several keys factors (soap, soil, time, and drying method) in reducing microorganisms during hand washing. A nonpathogenic nalidixic acid-resistant Enterobacter aerogenes surrogate for Salmonella was used to assess the efficacy of using soap or no soap for 5 or 20 s on hands with or without ground beef debris and drying with paper towel or air. Each experiment consisted of 20 replicates, each from a different individual with ∼ 6 log CFU/ml E. aerogenes on their hands. A reduction of 1.0 ± 0.4 and 1.7 ± 0.8 log CFU of E. aerogenes was observed for a 5-s wash with no soap and a 20-s wash with soap, respectively. When there was no debris on the hands, there was no significant difference between washing with and without soap for 20 s (P > 0.05). Likewise, there was no significant difference in the reductions achieved when washing without soap, whether or not debris was on the hands (P > 0.05). A significantly greater reduction (P soap when there was ground beef debris on the hands. The greatest difference (1.1 log CFU greater average reduction) in effectiveness occurred when ground beef debris was on the hands and a 20-s wash with water was compared with a 20-s wash with soap. Significantly greater (P 4.0 log CFU per towel) when hands are highly contaminated. Our results support future quantitative microbial risk assessments needed to effectively manage risks of foodborne illness in which food workers' hands are a primary cause.

  3. Hand Washing: Do's and Dont's

    Science.gov (United States)

    ... hands frequently can help limit the transfer of bacteria, viruses and other microbes. Always wash your hands before: Preparing food or eating Treating wounds or caring for a sick person Inserting or removing contact lenses Always wash your hands after: Preparing food Using ...

  4. Using Observational Data to Estimate the Effect of Hand Washing and Clean Delivery Kit Use by Birth Attendants on Maternal Deaths after Home Deliveries in Rural Bangladesh, India and Nepal.

    Directory of Open Access Journals (Sweden)

    Nadine Seward

    Full Text Available Globally, puerperal sepsis accounts for an estimated 8-12% of maternal deaths, but evidence is lacking on the extent to which clean delivery practices could improve maternal survival. We used data from the control arms of four cluster-randomised controlled trials conducted in rural India, Bangladesh and Nepal, to examine associations between clean delivery kit use and hand washing by the birth attendant with maternal mortality among home deliveries.We tested associations between clean delivery practices and maternal deaths, using a pooled dataset for 40,602 home births across sites in the three countries. Cross-sectional data were analysed by fitting logistic regression models with and without multiple imputation, and confounders were selected a priori using causal directed acyclic graphs. The robustness of estimates was investigated through sensitivity analyses.Hand washing was associated with a 49% reduction in the odds of maternal mortality after adjusting for confounding factors (adjusted odds ratio (AOR 0.51, 95% CI 0.28-0.93. The sensitivity analysis testing the missing at random assumption for the multiple imputation, as well as the sensitivity analysis accounting for possible misclassification bias in the use of clean delivery practices, indicated that the association between hand washing and maternal death had been over estimated. Clean delivery kit use was not associated with a maternal death (AOR 1.26, 95% CI 0.62-2.56.Our evidence suggests that hand washing in delivery is critical for maternal survival among home deliveries in rural South Asia, although the exact magnitude of this effect is uncertain due to inherent biases associated with observational data from low resource settings. Our findings indicating kit use does not improve maternal survival, suggests that the soap is not being used in all instances that kit use is being reported.

  5. 10 years with TAPS

    International Nuclear Information System (INIS)

    Loehneer, H.

    1997-01-01

    During the IV TAPS (two arm photon spectrometer) workshop held at Mont Saint Odile near Strasbourg the third of September, the TAPS collaboration celebrated its 10. anniversary. At this occasion a compilation entitled 'The first 10 years with TAPS' was issued. The foreword of the spokesperson of the TAPS collaboration is presented. (K.A.)

  6. Evaluation of the effects of repeated hand washing, sunlight, smoke and dirt on the persistence of deltamethrin on insecticide-treated nets.

    Science.gov (United States)

    Kayedi, M H; Lines, J D; Haghdoost, A A; Vatandoost, M H; Rassi, Y; Khamisabady, K

    2008-08-01

    Field studies were carried out in Iran to evaluate the effect of various factors (washing, sun, smoke, dust and dirt) on the residual insecticidal activity of PermaNet (a brand of long-lasting insecticidal net), and on nets conventionally treated with deltamethrin (K-O Tab), using bioassay tests. Thirty-two nets were washed five or 15 times, and eight nets were not washed at all. Nets were washed vigorously in cold tap water (17 degrees C, pH 8.9) with a detergent. Hand rubbing continued for 3min. After washing, some nets were exposed to dense smoke from a dung-hay fire for 3min and were also left exposed to the dusty wind between washes. One group of nets was exposed to the sunlight for the full 3-d interval between washes; another was exposed to sunlight for just 3h after each wash; two other groups were kept in the shade. There was a significantly greater loss of activity in nets exposed to the sun throughout the 3-d interval between washes: that is, for a total of 15 to 45 d. However, short sunlight exposure (maximum 3h between washes) during drying did not have any effect. We did not find any significant effect of exposure to dirt, dust and smoke after washing. It is concluded that the effect of sun is much smaller than that of washing, and that drying nets for a few hours in the sun is not harmful.

  7. Nickel in tap water

    DEFF Research Database (Denmark)

    Andersen, Klaus Ejner; Nielsen, G D; Flyvholm, Morten

    1983-01-01

    Nickel analyses of tap water from several sources in Copenhagen gave up to 490 X 10(-6) g X 1(-1) in the first 250 ml portions. Hot water gave higher values than cold water. After flushing for 5 min, low values were found. Considerable variation from time to time and from tap to tap was found...

  8. Nickel in tap water

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, K E; Nielsen, G D; Flyvholm, M A; Fregert, S; Gruvberge, B

    1983-03-01

    Nickel analyses of tap water from several sources in Copenhagen gave up to 490 X 10(-6) g X 1(-1) in the first 250 ml portions. Hot water gave higher values than cold water. After flushing for 5 min, low values were found. Considerable variation from time to time and from tap to tap was found. Drinking of only the first portion in the morning might have an influence on nickel hand eczema.

  9. Tapping with intentional drift

    NARCIS (Netherlands)

    Vardy, A.N.; Daffertshofer, A.; Beek, P.J.

    2009-01-01

    When tapping a desired frequency, subjects tend to drift away from this target frequency. This compromises the estimate of the correlation between inter-tap intervals (ITIs) as predicted by the two-level model of Wing and Kristofferson which consists of an internal timer ('clock') and motor delays.

  10. TAPS for Pupils

    Science.gov (United States)

    Earle, Sarah

    2018-01-01

    By placing the Focused Assessment approach within the TAPS pyramid framework, schools are beginning to find a number of ways in which learning in science can be enhanced for pupils. The quotations in this article provide examples of the ways in which science subject leaders (SSL) describe the impact of TAPS on their pupils.

  11. Technical Assistance Plan (TAP)

    Science.gov (United States)

    A Technical Assistance Plan (TAP) enables community groups to retain the services of an independent technical advisor and to provide resources for a community group to help inform other community members about site decisions.

  12. Propeller TAP flap

    DEFF Research Database (Denmark)

    Thomsen, Jørn Bo; Bille, Camilla; Wamberg, Peter

    2013-01-01

    major complications needing additional surgery. One flap was lost due to a vascular problem. Breast reconstruction can be performed by a propeller TAP flap without cutting the descending branch of the thoracodorsal vessels. However, the authors would recommend that a small cuff of muscle is left around...

  13. Physics of Beer Tapping

    OpenAIRE

    Rodríguez-Rodríguez , Javier; Casado-Chacón , Almudena; Fuster , Daniel

    2014-01-01

    International audience; The popular bar prank known in colloquial English as beer tapping consists in hitting the top of a beer bottle with a solid object, usually another bottle, to trigger the foaming over of the former within a few seconds. Despite the trick being known for long time, to the best of our knowledge, the phenomenon still lacks scientific explanation. Although it seems natural to think that shock-induced cavitation enhances the diffusion of CO2 from the supersaturated bulk liq...

  14. Physics of Beer Tapping

    Science.gov (United States)

    Rodríguez-Rodríguez, Javier; Casado-Chacón, Almudena; Fuster, Daniel

    2014-11-01

    The popular bar prank known in colloquial English as beer tapping consists in hitting the top of a beer bottle with a solid object, usually another bottle, to trigger the foaming over of the former within a few seconds. Despite the trick being known for a long time, to the best of our knowledge, the phenomenon still lacks scientific explanation. Although it seems natural to think that shock-induced cavitation enhances the diffusion of CO2 from the supersaturated bulk liquid into the bubbles by breaking them up, the subtle mechanism by which this happens remains unknown. Here, we show that the overall foaming-over process can be divided into three stages where different physical phenomena take place in different time scales: namely, the bubble-collapse (or cavitation) stage, the diffusion-driven stage, and the buoyancy-driven stage. In the bubble-collapse stage, the impact generates a train of expansion-compression waves in the liquid that leads to the fragmentation of preexisting gas cavities. Upon bubble fragmentation, the sudden increase of the interface-area-to-volume ratio enhances mass transfer significantly, which makes the bubble volume grow by a large factor until CO2 is locally depleted. At that point buoyancy takes over, making the bubble clouds rise and eventually form buoyant vortex rings whose volume grows fast due to the feedback between the buoyancy-induced rising speed and the advection-enhanced CO2 transport from the bulk liquid to the bubble. The physics behind this explosive process sheds insight into the dynamics of geological phenomena such as limnic eruptions.

  15. Tapping mode microwave impedance microscopy

    KAUST Repository

    Lai, K.; Kundhikanjana, W.; Peng, H.; Cui, Y.; Kelly, M. A.; Shen, Z. X.

    2009-01-01

    We report tapping mode microwave impedance imaging based on atomic force microscope platforms. The shielded cantilever probe is critical to localize the tip-sample interaction near the tip apex. The modulated tip-sample impedance can be accurately

  16. Tapping mode microwave impedance microscopy

    KAUST Repository

    Lai, K.

    2009-01-01

    We report tapping mode microwave impedance imaging based on atomic force microscope platforms. The shielded cantilever probe is critical to localize the tip-sample interaction near the tip apex. The modulated tip-sample impedance can be accurately simulated by the finite-element analysis and the result agrees quantitatively to the experimental data on a series of thin-film dielectric samples. The tapping mode microwave imaging is also superior to the contact mode in that the thermal drift in a long time scale is totally eliminated and an absolute measurement on the dielectric properties is possible. We demonstrated tapping images on working nanodevices, and the data are consistent with the transport results. © 2009 American Institute of Physics.

  17. Radioactive substances in tap water.

    Science.gov (United States)

    Atsuumi, Ryo; Endo, Yoshihiko; Suzuki, Akihiko; Kannotou, Yasumitu; Nakada, Masahiro; Yabuuchi, Reiko

    2014-01-01

    A 9.0 magnitude (M) earthquake with an epicenter off the Sanriku coast occurred at 14: 46 on March 11, 2011. TEPCO Fukushima Daiichi Nuclear Power Plant (F-1 NPP) was struck by the earthquake and its resulting tsunami. Consequently a critical nuclear disaster developed, as a large quantity of radioactive materials was released due to a hydrogen blast. On March 16(th), 2011, radioiodine and radioactive cesium were detected at levels of 177 Bq/kg and 58 Bq/kg, respectively, in tap water in Fukushima city (about 62km northwest of TEPCO F-1 NPP). On March 20th, radioiodine was detected in tap water at a level of 965 Bq/kg, which is over the value-index of restrictions on food and drink intake (radioiodine 300 Bq/kg (infant intake 100 Bq/kg)) designated by the Nuclear Safety Commission. Therefore, intake restriction measures were taken regarding drinking water. After that, although the all intake restrictions were lifted, in order to confirm the safety of tap water, an inspection system was established to monitor all tap water in the prefecture. This system has confirmed that there has been no detection of radioiodine or radioactive cesium in tap water in the prefecture since May 5(th), 2011. Furthermore, radioactive strontium ((89) Sr, (90)Sr) and plutonium ((238)Pu, (239)Pu+(240)Pu) in tap water and the raw water supply were measured. As a result, (89) Sr, (238)Pu, (239)Pu+(240)Pu were undetectable and although (90)Sr was detected, its committed effective dose of 0.00017 mSv was much lower than the yearly 0.1 mSv of the World Health Organization guidelines for drinking water quality. In addition, the results did not show any deviations from past inspection results.

  18. Geothermal Energy: Tapping the Potential

    Science.gov (United States)

    Johnson, Bill

    2008-01-01

    Ground source geothermal energy enables one to tap into the earth's stored renewable energy for heating and cooling facilities. Proper application of ground-source geothermal technology can have a dramatic impact on the efficiency and financial performance of building energy utilization (30%+). At the same time, using this alternative energy…

  19. Tapping into Industry and Academia

    DEFF Research Database (Denmark)

    Markus, Arjan; Rosenkopf, Lori

    This paper studies how different boundary-spanning mechanisms concurrently impact firm innovation. We specifically examine how inbound mobility and R&D collaboration interact when firms use these mechanisms to tap into two distinct knowledge domains: industry and academia. To examine the impacts...

  20. Introducing the TAPS Pyramid Model

    Science.gov (United States)

    Earle, Sarah

    2015-01-01

    The Teacher Assessment in Primary Science (TAPS) project is a three-year project based at Bath Spa University and funded by the Primary Science Teaching Trust (PSTT). It aims to develop support for a valid, reliable and manageable system of science assessment that will have a positive impact on children's learning. In this article, the author…

  1. 49 CFR 192.151 - Tapping.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Tapping. 192.151 Section 192.151 Transportation... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Design of Pipeline Components § 192.151 Tapping. (a) Each mechanical fitting used to make a hot tap must be designed for at least the operating pressure of...

  2. FOCUS ON HAND WASHING Yakubu Tahir Maigari Departm

    African Journals Online (AJOL)

    HP

    2014-10-24

    Oct 24, 2014 ... Management and Social Sciences, Federal University Kashere,. Gombe State ... Peace can also be maintained with fellow human beings through ... talent and skill to build a mighty ship with which he and his people took .... One important aspect of Islamic rituals where washing of hands is prominent is ...

  3. ignas semmelweis: the doctor who championed hand -washing

    African Journals Online (AJOL)

    1). He died on 13th August 1867 at the age of 47 years in Vienna, Australia. He initially studied law at the University of Vienna in 1837 but changed to medicine in 1838 obtaining his doctorate degree in 1844. He later specialized in obstetrics.

  4. Effectiveness Of Different House-Hold Hand Washing Agents On ...

    African Journals Online (AJOL)

    Hand hygiene is a very important procedure in infection control. Washing agents commonly in use were investigated for their effectiveness in reducing hand floral and cotton towel was used as drying agent. Agents studied include; water alone, carex soap, dettol, and imperial leather. The hands were inoculated (deliberate ...

  5. Assessment of knowledge of hand washing among health care ...

    African Journals Online (AJOL)

    Introduction. Nosocomial infection is a global public health problem with an estimated 1.5 million suffering consequences at any given time [1, 2] noted that at least 25% of all hospital infections in the developing world are nosocomially acquired. The hands of health care providers are major agents of infection transmission ...

  6. Contamination Control and Monitoring of Tap Water as Fluid in Industrial Tap Water Hydraulic Systems

    DEFF Research Database (Denmark)

    Conrad, Finn; Adelstorp, Anders

    1998-01-01

    Presentation of results and methods addressed to contamination control and monitoring of tap water as fluid in tap water hydraulic systems.......Presentation of results and methods addressed to contamination control and monitoring of tap water as fluid in tap water hydraulic systems....

  7. Bilateral transversus abdominis plane (TAP) block with 24 hours ropivacaine infusion via TAP catheters

    DEFF Research Database (Denmark)

    Petersen, Pernille L; Hilsted, Karen L; Dahl, Jørgen B

    2013-01-01

    The analgesic effect of a TAP block has been investigated in various surgical settings. There are however limited information about block level and block duration. Furthermore, there is a lack of information about continuous TAP block after ultrasound-guided posterior TAP blocks.The aim of this d...... of this double-blind randomized study was therefore to investigate the effect of an ultrasound-guided posterior TAP block with 24 hours local anesthetic infusion via a TAP catheter....

  8. The physics of Beer Tapping

    OpenAIRE

    Rodriguez-Rodriguez, Javier

    2015-01-01

    The popular bar prank known in colloquial English as beer tapping consists in hitting the top of a beer bottle with a solid object, usually another bottle, to trigger the foaming over of the former within a few seconds. Despite the trick being nown for a long time, to the best of our knowledge, the phenomenon still lacked scientific explanation. Although it seems natural to think that shock-induced cavitation enhances the diffusion of CO2 from the supersaturated bulk liquid into the bub...

  9. Electronic tap-changer for distribution transformers

    CERN Document Server

    Faiz, Jawad

    2011-01-01

    This reference collects all relevant aspects electronic tap-changer and presents them in a comprehensive and orderly manner. It explains logically and systematically the design and optimization of a full electronic tap-changer for distribution transformers. The book provides a fully new insight to all possible structures of power section design and categorizes them comprehensively, including cost factors of the design. In the control section design, the authors review mechanical tap-changer control systems and they present the modeling of a full electronic tap-changer as well as a closed-loop

  10. Tapping mode atomic force microscopy in liquid

    NARCIS (Netherlands)

    Putman, Constant A.J.; Putman, C.A.J.; van der Werf, Kees; de Grooth, B.G.; van Hulst, N.F.; Greve, Jan

    1994-01-01

    We show that standard silicon nitride cantilevers can be used for tapping mode atomic force microscopy (AFM) in air, provided that the energy of the oscillating cantilever is sufficiently high to overcome the adhesion of the water layer. The same cantilevers are successfully used for tapping mode

  11. Military Transition Assistance Program (TAP): An Overview

    Science.gov (United States)

    2017-03-15

    in the development, management oversight, and strategic planning of TAP. TAP Counseling Requirements Over time, Congress has increased the...training, and placement services provided under qualified job training programs of the DOL* Veterans small business ownership and entrepreneurship ...Accessing Higher Education (DOD) Career Technical Training (VA) Entrepreneurship (SBA) Capstone Verifies that servicemembers have met Career

  12. Electronic tap-changer for distribution transformers

    Energy Technology Data Exchange (ETDEWEB)

    Faiz, Jawad [Tehran Univ. (Iran, Islamic Republic of). Univ. College of Engineering; Siahkolah, Behzad [Kavandish Company, Tehran (Iran, Islamic Republic of)

    2011-07-01

    This reference collects all relevant aspects electronic tap-changer and presents them in a comprehensive and orderly manner. It explains logically and systematically the design and optimization of a full electronic tap-changer for distribution transformers. The book provides a fully new insight to all possible structures of power section design and categorizes them comprehensively, including cost factors of the design. In the control section design, the authors review mechanical tap-changer control systems and they present the modeling of a full electronic tap-changer as well as a closed-loop control of the full-electronic tap-changer. The book is written for electrical engineers in industry and academia but should be useful also to postgraduate students of electrical engineering. (orig.)

  13. Higienização das mãos: o ensino e a prática entre graduandos na área da saúde - DOI: 10.4025/actascihealthsci.1079 Hand washing: teaching and practice among undergraduate health sector students - DOI: 10.4025/actascihealthsci.1079

    Directory of Open Access Journals (Sweden)

    Milca Severino Pereira

    2008-03-01

    Full Text Available Estudo realizado com graduandos do último ano/semestre da área da saúde de Instituições de Ensino Superior (IES em Goiás/2005, com objetivo de verificar a compreensão destes acerca da higienização das mãos (HM, identificar a contribuição das IES na formação dos alunos sobre esta temática, identificar fatores que favorecem a adesão à HM e verificar a disponibilidade de recursos materiais para HM nos Estabelecimentos de Assistência à Saúde (EAS utilizados como cenários de prática. Observados os aspectos éticos, os dados foram obtidos pela aplicação de questionário, previamente avaliado, e processados no programa Epiinfo (CDC, 2004, quando indicado, aplicado o teste qui-quadrado. Participaram do estudo 777 graduandos (68,0%; dos cursos de Biomedicina, Enfermagem, Farmácia, Fisioterapia, Fonoaudiologia, Medicina, Odontologia e Terapia Ocupacional. Houve discordância entre o entendimento sobre HM e a adesão. Embora tenhamos evidenciado que as IES tenham abordado este tema durante a formação dos profissionais, isto não foi suficiente para alterar a práxisThis study was undertaken with students during their last year/semester of health sector studies at Higher Education Institutions (HEI, in Goiás State/2005. It aimed to verify the understanding of these students about hands washing (HW, identify the contribution of the HEI to the students’ education on this theme, identify factors that favor the practice of HW, and verify the availability of material resources for HW at Health Assistance Establishments (HAE used as practice scenarios. After observing ethical aspects, the data was obtained through a previously-evaluated questionnaire, and processed using Epi Info software (CDC, 2004, when the chi-square test was applied. 777 students took part (68.0% in the study, belonging to the following courses: Biomedicine, Nursing, Pharmacy, physiotherapy, phonoaudiology, Medicine, Dentistry and Occupational Therapy. There was

  14. Freely Chosen Index Finger Tapping Frequency Is Increased in Repeated Bouts of Tapping.

    Science.gov (United States)

    Hansen, Ernst Albin; Ebbesen, Brian Duborg; Dalsgaard, Ane; Mora-Jensen, Mark Holten; Rasmussen, Jakob

    2015-01-01

    Healthy individuals (n = 40) performed index finger tapping at freely chosen frequency during repeated bouts and before and after near-maximal muscle action consisting of 3 intense flexions of the index finger metacarpal phalangeal joint. One experiment showed, unexpectedly, that a bout of tapping increased the tapping frequency in the subsequent bout. Thus, a cumulating increase of 8.2 ± 5.4% (p tapping frequency was still increased in consecutive bouts when rest periods were extended to 20 min. Besides, near-maximal muscle activation, followed by 5 min rest, did not affect the tapping frequency. In conclusion, freely chosen tapping frequency was increased in repeated bouts of tapping, which were separated by 10-20 min rest periods. The observed phenomenon is suggested to be termed repeated bout rate enhancement.

  15. Tapping a new energy source

    International Nuclear Information System (INIS)

    Thomas, W.

    1999-01-01

    The Sable Offshore Energy Project is one of Canada's largest construction projects which is bringing a new industry to Nova Scotia. A five-party consortium comprised of Mobil Oil Canada, Shell Canada, Imperial Oil, Nova Scotia Resources and Mosbacher, has formed an enterprise called Sable Offshore Energy Inc. The consortium plans to bring natural gas to markets in Canada and the United States before the end of 1999. The Santa Fe Galaxy II is one of the world's most modern marine all-weather drilling rigs that will soon begin the drilling of wells. Once in production, the project will produce half a billion cubic feet of natural gas daily from three production platforms that will tap three separate undersea natural gas fields. The gas will then be transported 200 km to shore near Goldboro, Nova Scotia, through an undersea pipeline. There, it will be treated to remove any remaining water and to separate liquid natural gas from the gas proper. The natural gas liquids will then be carried by an onshore pipeline to a new facility at Point Tupper where they will be processed into propane, butane and condensate. There will be enough gas to meet the potential demand in Nova Scotia and New Brunswick. Large urban centres such as Halifax and Saint John will be served by secondary lines that branch off the main pipeline, but developing smaller markets will take time because the necessary infrastructure does not yet exist. The project has already created thousands of jobs in the province. 5 figs

  16. Lower extremity kinetics in tap dance.

    Science.gov (United States)

    Mayers, Lester; Bronner, Shaw; Agraharasamakulam, Sujani; Ojofeitimi, Sheyi

    2010-01-01

    Tap dance is a unique performing art utilizing the lower extremities as percussion instruments. In a previous study these authors reported decreased injury prevalence among tap dancers compared to other dance and sports participants. No biomechanical analyses of tap dance exist to explain this finding. The purpose of the current pilot study was to provide a preliminary overview of normative peak kinetic and kinematic data, based on the hypothesis that tap dance generates relatively low ground reaction forces and joint forces and moments. Six professional tap dancers performed four common tap dance sequences that produced data captured by the use of a force platform and a five-camera motion analysis system. The mean vertical ground reaction force for all sequences was found to be 2.06+/-0.55 BW. Mean peak sagittal, frontal, and transverse plane joint moments (hip, knee, and ankle) ranged from 0.07 to 2.62 N.m/kg. These small ground reaction forces and joint forces and moments support our hypothesis, and may explain the relatively low injury incidence in tap dancers. Nevertheless, the analysis is highly complex, and other factors remain to be studied and clarified.

  17. The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins.

    Science.gov (United States)

    Praest, P; Luteijn, R D; Brak-Boer, I G J; Lanfermeijer, J; Hoelen, H; Ijgosse, L; Costa, A I; Gorham, R D; Lebbink, R J; Wiertz, E J H J

    2018-06-04

    Herpesviruses encode numerous immune evasion molecules that interfere with the immune system, particularly with certain stages in the MHC class I antigen presentation pathway. In this pathway, the transporter associated with antigen processing (TAP) is a frequent target of viral immune evasion strategies. This ER-resident transporter is composed of the proteins TAP1 and TAP2, and plays a crucial role in the loading of viral peptides onto MHC class I molecules. Several variants of TAP1 and TAP2 occur in the human population, some of which are linked to autoimmune disorders and susceptibility to infections. Here, we assessed the influence of naturally occurring TAP variants on peptide transport and MHC class I expression. In addition, we tested the inhibitory capacity of three viral immune evasion proteins, the TAP inhibitors US6 from human cytomegalovirus, ICP47 from herpes simplex virus type 1 and BNLF2a from Epstein-Barr virus, for a series of TAP1 and TAP2 variants. Our results suggest that these TAP polymorphisms have no or limited effect on peptide transport or MHC class I expression. Furthermore, our study indicates that the herpesvirus-encoded TAP inhibitors target a broad spectrum of TAP variants; inhibition of TAP is not affected by the naturally occurring polymorphisms of TAP tested in this study. Our findings suggest that the long-term coevolution of herpesviruses and their host did not result in selection of inhibitor-resistant TAP variants in the human population. Copyright © 2018. Published by Elsevier Ltd.

  18. Energy-Saving RAM-Power Tap

    Science.gov (United States)

    Bruner, Alan Roy

    1987-01-01

    Reverse-flow HEXFET(R) minimizes voltage drop and power dissipation. HEXFET(R) scheme reduces voltage drop by approximately 80 percent. Design for power tap for random-access memory (RAM) has potential application in digital systems.

  19. Sinusitis from Nontuberculous Mycobacteria in Tap Water

    Centers for Disease Control (CDC) Podcasts

    Dr. Wellington S. Tichenor. Associate Clinical Professor of Medicine at New York Medical College and in private practice in Manhattan, New York, discusses his investigation of sinusitis from nontuberculous mycobacteria in tap water.

  20. Ormen Lange hot tap - a world record

    Energy Technology Data Exchange (ETDEWEB)

    Apeland, Kjell Edvard

    2010-07-01

    For the last 10 years Statoil have been developing a new concept for performing subsea Hot Tap operations remotely controlled. The system was first used offshore in 2008 during a partly diver assisted operation, connecting the Tampen Link pipeline to the Statfjord Intrafield pipeline. In July 2009, the Hot Tap System successfully performed two remotely controlled Hot Taps, on a world record depth of 860 meters on the Ormen Lange field operated by Shell. The Hot Tap technology enables existing pipeline architecture to be modified, without interfering with the current production. Most of the technology is depth independent and the system is currently qualified to 1000 meter depth. Phase II of this project which involves development and construction of a retrofit Tee, thus enabling installation and welding of a Tee on an unprepared pipeline is well underway. This presentation will describe experiences from the development of the Remote Hot Tap system and give an overview of the offshore operations leading to the conclusion of the world's deepest Hot Taps. (Author)

  1. Biomechanical loading on the upper extremity increases from single key tapping to directional tapping.

    Science.gov (United States)

    Qin, Jin; Trudeau, Matthieu; Katz, Jeffrey N; Buchholz, Bryan; Dennerlein, Jack T

    2011-08-01

    Musculoskeletal disorders associated with computer use span the joints of the upper extremity. Computing typically involves tapping in multiple directions. Thus, we sought to describe the loading on the finger, wrist, elbow and shoulder joints in terms of kinematic and kinetic difference across single key switch tapping to directional tapping on multiple keys. An experiment with repeated measures design was conducted. Six subjects tapped with their right index finger on a stand-alone number keypad placed horizontally in three conditions: (1) on single key switch (the number key 5); (2) left and right on number key 4 and 6; (3) top and bottom on number key 8 and 2. A force-torque transducer underneath the keypad measured the fingertip force. An active-marker infrared motion analysis system measured the kinematics of the fingertip, hand, forearm, upper arm and torso. Joint moments for the metacarpophalangeal, wrist, elbow, and shoulder joints were estimated using inverse dynamics. Tapping in the top-bottom orientation introduced the largest biomechanical loading on the upper extremity especially for the proximal joint, followed by tapping in the left-right orientation, and the lowest loading was observed during single key switch tapping. Directional tapping on average increased the fingertip force, joint excursion, and peak-to-peak joint torque by 45%, 190% and 55%, respectively. Identifying the biomechanical loading patterns associated with these fundamental movements of keying improves the understanding of the risks of upper extremity musculoskeletal disorders for computer keyboard users. Copyright © 2010 Elsevier Ltd. All rights reserved.

  2. The largest subsea hot tap (future tap flange) at Angel Field, Australia

    Energy Technology Data Exchange (ETDEWEB)

    Lad, Deepak; Drysdale, Colin [T.D. Williamson (United States); Naidoo, Sashie [T.D. Williamson (Australia)

    2008-07-01

    A subsea hot tap was conducted near the gas production platforms in Angel Field, Australia in September 2007 and verified as the largest no. 900 subsea hot tap by Australian authorities. This paper outlines the subsea tapping process, risks and safety issues in deep water environment, including the need to ensure 100% system accuracy and that the machine fluids used to operate the subsea tapping machines were environmentally friendly. The testing phase included land and water testing. In the land tests, issues relating to metal hardness, temperature, pressure and ocean currents that affected machine stability, torque and cutting rate were considered. All preliminary design and testing focused on being able to mount the tapping machine to a pre-existing hot-tap flange and conduct the tapping operation, start to finish, preferably without changing the cutter. The water depth tests took place inside a pressurized, underwater hyperbaric chamber. The equipment repeated the land testing process in conditions duplicating that of the actual project site. Timing was also measured in multiple climatic conditions (except water depth) to obtain an estimation of various scenarios. The field tapping process was conducted without problems in over six hours with a single cutter and without any stalls. (author)

  3. More than just tapping: index finger-tapping measures procedural learning in schizophrenia.

    Science.gov (United States)

    Da Silva, Felipe N; Irani, Farzin; Richard, Jan; Brensinger, Colleen M; Bilker, Warren B; Gur, Raquel E; Gur, Ruben C

    2012-05-01

    Finger-tapping has been widely studied using behavioral and neuroimaging paradigms. Evidence supports the use of finger-tapping as an endophenotype in schizophrenia, but its relationship with motor procedural learning remains unexplored. To our knowledge, this study presents the first use of index finger-tapping to study procedural learning in individuals with schizophrenia or schizoaffective disorder (SCZ/SZA) as compared to healthy controls. A computerized index finger-tapping test was administered to 1169 SCZ/SZA patients (62% male, 88% right-handed), and 689 healthy controls (40% male, 93% right-handed). Number of taps per trial and learning slopes across trials for the dominant and non-dominant hands were examined for motor speed and procedural learning, respectively. Both healthy controls and SCZ/SZA patients demonstrated procedural learning for their dominant hand but not for their non-dominant hand. In addition, patients showed a greater capacity for procedural learning even though they demonstrated more variability in procedural learning compared to healthy controls. Left-handers of both groups performed better than right-handers and had less variability in mean number of taps between non-dominant and dominant hands. Males also had less variability in mean tap count between dominant and non-dominant hands than females. As expected, patients had a lower mean number of taps than healthy controls, males outperformed females and dominant-hand trials had more mean taps than non-dominant hand trials in both groups. The index finger-tapping test can measure both motor speed and procedural learning, and motor procedural learning may be intact in SCZ/SZA patients. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Steady state of tapped granular polygons

    International Nuclear Information System (INIS)

    Carlevaro, Carlos M; Pugnaloni, Luis A

    2011-01-01

    The steady state packing fraction of a tapped granular bed is studied for different grain shapes via a discrete element method. Grains are monosized regular polygons, from triangles to icosagons. Comparisons with disc packings show that the steady state packing fraction as a function of the tapping intensity presents the same general trends in polygon packings. However, better packing fractions are obtained, as expected, for shapes that can tessellate the plane (triangles, squares and hexagons). In addition, we find a sharp transition for packings of polygons with more than 13 vertices signaled by a discontinuity in the packing fraction at a particular tapping intensity. Density fluctuations for most shapes are consistent with recent experimental findings in disc packing; however, a peculiar behavior is found for triangles and squares

  5. Fluctuation of biological rhythm in finger tapping

    Science.gov (United States)

    Yoshinaga, H.; Miyazima, S.; Mitake, S.

    2000-06-01

    By analyzing biological rhythms obtained from finger tapping, we have investigated the differences of two biological rhythms between healthy and handicapped persons caused by Parkinson, brain infraction, car accident and so on. In this study, we have observed the motion of handedness of all subjects and obtained a slope a which characterizes a power-law relation between frequency and amplitude of finger-tapping rhythm. From our results, we have estimated that the slope a=0.06 is a rough criterion in order to distinguish healthy and handicapped persons.

  6. Inserting the tap values of the tap changer transformers into the Jacobian matrix as control variables

    Directory of Open Access Journals (Sweden)

    Faruk Yalçın

    2013-06-01

    Full Text Available Series and shunt admittance values of under load tap changer transformers are changed according to tap changing. As this situation changes the structure of bus admittance matrix, it causes the need of rebuilding the bus admittance matrix at each tap changing case in power flow studies. In this paper, a new approach that includes the tap changing effects into the Jacobian matrix. By this approach, the need of rebuilding the bus admittance matrix at each tap changing case during power flow study is prevented. So, fast convergence is achieved for the power flow algorithm. Although there are similar studies for this aim in the literature, apart from these studies, including the tap changing effects to the Jacobian matrix when more than one under load tap changer transformers are connected to the same bus with different connection combinations is provided by the proposed approach. For this aim, new power equations and new Jacobian matrix component calculation equations are obtained. The proposed approach is tested on IEEE 57-bus test system and its accuracy is proved.

  7. 10BASE5 Ethernet Cable & Vampire Tap

    CERN Document Server

    1983-01-01

    10BASE5 Thick Ethernet Cable, 10Mbit/sec. In the 1980s and early 1990's, Ethernet became more popular and provided a much faster data transmission rate. This cable is one of the first ethernet cables from 1983, a thick, bulky affair. Computers were attached via "Vampire Taps" which were connectors screwed straight through the shielding of the cable.

  8. Workshop on physics related to TAPS

    International Nuclear Information System (INIS)

    Kuehn, W.; Loehner, H.

    1991-06-01

    Since December 1989 there exist two accepted proposals for TAPS experiments at SIS: 'η production in Relativistic Heavy Ion Experiments' (S 025) and 'π 0 Excitation Function and π 0 -π 0 Correlations Combined with Charged Particle Flow Analysis' (S 042). A third proposal 'Electromagnetic Excitations' (S 046) was submitted and is accepted by now. Before the new phase with data taking and detailed analysis of relativistic heavy ion data was about to begin, it was feld that there should be a few days set aside to take breath and to consider in a relaxed atmosphere the physics goals for which TAPS was constructed. The large number of undergraduate and graduate students in the collaboration was additional good reason to plan a meeting in a workshop-like atmosphere in order to communicate recent experimental and theoretical results touching the goals of TAPS and to discuss the aims of the submitted proposals and methods of the respective data analysis. Moreover, new ideas for future proposals and advanced technical developments should also be discussed. The aim was to broaden the view for applications of TAPS for photon and neutral meson measurements at the different accelerators at GANIL(Caen), SIS(GSI), MAMI(Mainz) and AGOR(KVI). See hints under the relevant topics. (orig./HSI)

  9. Sinusitis from Nontuberculous Mycobacteria in Tap Water

    Centers for Disease Control (CDC) Podcasts

    2012-12-21

    Dr. Wellington S. Tichenor. Associate Clinical Professor of Medicine at New York Medical College and in private practice in Manhattan, New York, discusses his investigation of sinusitis from nontuberculous mycobacteria in tap water.  Created: 12/21/2012 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 12/31/2012.

  10. Ideomotor effects of pitch on continuation tapping.

    Science.gov (United States)

    Ammirante, Paolo; Thompson, William F; Russo, Frank A

    2011-02-01

    The ideomotor principle predicts that perception will modulate action where overlap exists between perceptual and motor representations of action. This effect is demonstrated with auditory stimuli. Previous perceptual evidence suggests that pitch contour and pitch distance in tone sequences may elicit tonal motion effects consistent with listeners' implicit awareness of the lawful dynamics of locomotive bodies. To examine modulating effects of perception on action, participants in a continuation tapping task produced a steady tempo. Auditory tones were triggered by each tap. Pitch contour randomly and persistently varied within trials. Pitch distance between successive tones varied between trials. Although participants were instructed to ignore them, tones systematically affected finger dynamics and timing. Where pitch contour implied positive acceleration, the following tap and the intertap interval (ITI) that it completed were faster. Where pitch contour implied negative acceleration, the following tap and the ITI that it completed were slower. Tempo was faster with greater pitch distance. Musical training did not predict the magnitude of these effects. There were no generalized effects on timing variability. Pitch contour findings demonstrate how tonal motion may elicit the spontaneous production of accents found in expressive music performance.

  11. The TAPS Pyramid: Where, Who and How?

    Science.gov (United States)

    Hopwood-Stephens, Isabel

    2018-01-01

    The TAPS pyramid was developed in late 2014 and has been available as a download on the Primary Science Teaching Trust (PSTT) website since August 2015. But where has it gone since then? Who is using it? And how is it being used in schools to change primary science assessment practice? This article attempts to answer these questions with data from…

  12. Monitoring chlorination practices during operation at TAPS

    International Nuclear Information System (INIS)

    Sriraman, A.K.; Wani, B.N.; Gokhale, A.S.; Yuvaraju, B.

    1995-01-01

    Chlorination of cooling waters is aimed at the condenser surfaces to minimize the biogrowth, while the residual oxidants in the effluents are negligible. This paper describes the fulfillment of the above criteria, as observed during the monitoring of chlorination practices at Tarapur Atomic Power Station (TAPS) during 1990. (author). 4 refs., 2 tabs

  13. Study of heavy ion collisions with TAPS

    NARCIS (Netherlands)

    Löhner, H.

    The photon spectrometer TAPS is a versatile instrument to measure nuclear bremsstrahlung and neutral mesons via their gamma decay. The formation and evolution of compressed nuclear matter is studied in heavy ion collisions at relativistic energies by analyzing the yield and spectral distribution of

  14. Chapter 13. Industrial Application of Tap Water Hydraulic Systems

    DEFF Research Database (Denmark)

    Conrad, Finn; Adelstorp, Anders

    1997-01-01

    Design and application of modern pure tap water components and systems in industries, in particular food processing industry.......Design and application of modern pure tap water components and systems in industries, in particular food processing industry....

  15. Chapter 12. Pure Tap Water Hydraulic Systems and Applications

    DEFF Research Database (Denmark)

    Conrad, Finn; Adelstorp, Anders

    1997-01-01

    Presentation of developed a modern pure tap water hydraulic components (Nessie), systems and industrial applications.......Presentation of developed a modern pure tap water hydraulic components (Nessie), systems and industrial applications....

  16. Finger-tapping motion analysis in cervical myelopathy by magnetic-sensor tapping device.

    Science.gov (United States)

    Miwa, Toshitada; Hosono, Noboru; Mukai, Yoshihiro; Makino, Takahiro; Kandori, Akihiko; Fuji, Takeshi

    2013-08-01

    Case-control study. The purpose of this study is to determine finger motion of patients with cervical myelopathy during finger-tapping cycles. A major symptom of patients with compressive cervical myelopathy is finger clumsiness. Therefore, understanding finger motion is prerequisite in assessing the severity of myelopathy. The popular grip-and-release test evaluates only the number of motion cycles, which is insufficient to fully describe complex finger motion. Forty-three patients with cervical myelopathy and 41 healthy controls tapped their index fingers against their thumbs as rapidly as possible for 30 seconds and the motion was recorded by a magnetic-sensor coil attached to the nail surface. Output signals were stored in a computer, which automatically calculated tapping frequency, distance moved, ratio of opening/closing velocity and the SD of the tapping interval. The SD of the tapping interval was significantly greater and all other measures were significantly smaller in patients with cervical myelopathy, than in healthy controls. All indices significantly improved after surgical decompression of the cervical spine. Distance moved (Pearson correlation coefficient: r=0.590, Ptapping interval (r=-0.451; P=0.002) were significantly correlated with the Japanese Orthopedic Association score (neurological scale). The quantitative evaluation of finger paralysis was performed by this tapping device. Speed and regularity in repetitive motion of fingers were correlated with the severity of cervical myelopathy.

  17. Multiplication of Legionella pneumophila in unsterilized tap water.

    OpenAIRE

    Yee, R B; Wadowsky, R M

    1982-01-01

    Naturally occurring Legionella pneumophila, an environmental isolate which had not been grown on artificial medium, was tested for the ability to multiply in tap water. A showerhead containing L. pneumophila and non-Legionellaceae bacteria was immersed in nonsterile tap water supplying this fixture. Also L. pneumophila and non-Legionellaceae bacteria were sedimented from tap water from a surgical intensive care unit. This bacterial suspension was inoculated into tap water from our laboratory....

  18. Supportive supervision for volunteers to deliver reproductive health education: a cluster randomized trial.

    Science.gov (United States)

    Singh, Debra; Negin, Joel; Orach, Christopher Garimoi; Cumming, Robert

    2016-10-03

    Community Health Volunteers (CHVs) can be effective in improving pregnancy and newborn outcomes through community education. Inadequate supervision of CHVs, whether due to poor planning, irregular visits, or ineffective supervisory methods, is, however, recognized as a weakness in many programs. There has been little research on best practice supervisory or accompaniment models. From March 2014 to February 2015 a proof of concept study was conducted to compare training alone versus training and supportive supervision by paid CHWs (n = 4) on the effectiveness of CHVs (n = 82) to deliver education about pregnancy, newborn care, family planning and hygiene. The pair-matched cluster randomized trial was conducted in eight villages (four intervention and four control) in Budondo sub-county in Jinja, Uganda. Increases in desired behaviors were seen in both the intervention and control arms over the study period. Both arms showed high retention rates of CHVs (95 %). At 1 year follow-up there was a significantly higher prevalence of installed and functioning tippy taps for hand washing (p services. Supportive supervision involves creating a non-threatening, empowering environment in which both the CHV and the supervising CHW learn together and overcome obstacles that might otherwise demotivate the CHV. While the results seem promising for added value with supportive supervision for CHVs undertaking reproductive health activities, further research on a larger scale will be needed to substantiate the effect.

  19. 49 CFR 192.627 - Tapping pipelines under pressure.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Tapping pipelines under pressure. 192.627 Section... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Operations § 192.627 Tapping pipelines under pressure. Each tap made on a pipeline under pressure must be performed by a crew qualified to make...

  20. Preheating of tap water with solar collectors

    Energy Technology Data Exchange (ETDEWEB)

    Granum, H; Raaen, H

    1992-05-05

    In 1991 SINTEF Architecture and Building Technology won the second prize in 'The Nordic Competition for Low Energy Buildings' with a project proposal named 'LOWe'. The paper gives a description of the energy-saving features of this project, particularly the use of a solar collector for preheating of tap water. Compared with the economic profitability of other saving efforts in the project, such as good thermal insulation and efficient heat recovering system, the system for solar preheating of tap water does not seem very attractive for the time being. Loose estimates indicate a cost of close of NOK 1.00 per kWh for the produced energy in the solar collector, while the present price for electricity in Norway is about NOK 0.50 per kWh. Compared with a heat pump solution however the energy cost is not unreasonable.

  1. Beer tapping: dynamics of bubbles after impact

    OpenAIRE

    Mantic-Lugo, V.; Cayron, A.; Brun, P-T; Gallaire, F.

    2015-01-01

    Beer tapping is a well known prank where a bottle of beer is impacted from the top by a solid object, usually another bottle, leading to a sudden foam overflow. A description of the shock-driven bubble dynamics leading to foaming is presented based on an experimental and numerical study evoking the following physical picture. First, the solid impact produces a sudden downwards acceleration of the bottle creating a strong depression in the liquid bulk. The existing bubbles undergo a strong exp...

  2. Single quadrature duplication and transparent taps

    International Nuclear Information System (INIS)

    Kim, Ajung

    2004-01-01

    The concept of single quadrature duplication, which is the process of producing two outputs with the same homodyne detecting statistics as an input, is addressed. This device has important potential application to optical communications as a transparent optical tap in a local area network environment. The characteristics of the device are examined, and a realization scheme employing a coupler and phase-sensitive amplifiers is proposed

  3. Relay self interference minimisation using tapped filter

    KAUST Repository

    Jazzar, Saleh

    2013-05-01

    In this paper we introduce a self interference (SI) estimation and minimisation technique for amplify and forward relays. Relays are used to help forward signals between a transmitter and a receiver. This helps increase the signal coverage and reduce the required transmitted signal power. One problem that faces relays communications is the leaked signal from the relay\\'s output to its input. This will cause an SI problem where the new received signal at the relay\\'s input will be added with the unwanted leaked signal from the relay\\'s output. A Solution is proposed in this paper to estimate and minimise this SI which is based upon using a tapped filter at the destination. To get the optimum weights for this tapped filter, some channel parameters must be estimated first. This is performed blindly at the destination without the need of any training. This channel parameter estimation method is named the blind-self-interference-channel-estimation (BSICE) method. The next step in the proposed solution is to estimate the tapped filter\\'s weights. This is performed by minimising the mean squared error (MSE) at the destination. This proposed method is named the MSE-Optimum Weight (MSE-OW) method. Simulation results are provided in this paper to verify the performance of BSICE and MSE-OW methods. © 2013 IEEE.

  4. What's Wrong with the Tap? Examining Perceptions of Tap Water and Bottled Water at Purdue University

    Science.gov (United States)

    Saylor, Amber; Prokopy, Linda Stalker; Amberg, Shannon

    2011-09-01

    The environmental impacts of bottled water prompted us to explore drinking water choices at Purdue University, located in West Lafayette, IN. A random sample of 2,045 Purdue University students, staff, and faculty was invited to participate in an online survey. The survey assessed current behaviors as well as perceived barriers and benefits to drinking tap water versus bottled water. 677 surveys were completed for a response rate of 33.1%. We then conducted qualitative interviews with a purposive sample of university undergraduates ( n = 21) to obtain contextual insights into the survey results and the beliefs of individuals with a variety of drinking water preferences. This study revealed that women drink disproportionately more bottled water then men while undergraduate students drink more than graduate students, staff and faculty. The study also uncovered a widespread belief that recycling eliminates the environmental impacts of bottled water. Important barriers to drinking tap water at Purdue include: perceived risks from tap water and the perceived safety of bottled water, preferring the taste of bottled water, and the convenience of drinking bottled water. The qualitative interviews revealed that drinking water choices can be influenced by several factors—especially whether individuals trust tap water to be clean—but involve varying levels of complexity. The implications of these results for social marketing strategies to promote tap water are discussed.

  5. Spontaneous eye blinks are entrained by finger tapping.

    Science.gov (United States)

    Cong, D-K; Sharikadze, M; Staude, G; Deubel, H; Wolf, W

    2010-02-01

    We studied the mutual cross-talk between spontaneous eye blinks and continuous, self-paced unimanual and bimanual tapping. Both types of motor activities were analyzed with regard to their time-structure in synchronization-continuation tapping tasks which involved different task instructions, namely "standard" finger tapping (Experiment 1), "strong" tapping (Experiment 2) requiring more forceful finger movements, and "impulse-like" tapping (Experiment 3) where upward-downward finger movements had to be very fast. In a further control condition (Experiment 4), tapping was omitted altogether. The results revealed a prominent entrainment of spontaneous blink behavior by the manual tapping, with bimanual tapping being more effective than unimanual tapping, and with the "strong" and "impulse-like" tapping showing the largest effects on blink timing. Conversely, we found no significant effects of the tapping on the timing of the eye blinks across all experiments. The findings suggest a functional overlap of the motor control structures responsible for voluntary, rhythmic finger movements and eye blinking behavior.

  6. Propensity for obtaining alcohol through shoulder tapping.

    Science.gov (United States)

    Toomey, Traci L; Fabian, Lindsey E A; Erickson, Darin J; Lenk, Kathleen M

    2007-07-01

    Underage youth often obtain alcohol from adults who illegally provide the alcohol. One method for obtaining alcohol from adults is shoulder tapping, where youth approach an adult outside an alcohol establishment and ask the adult to purchase alcohol for them. The goal of this study was to assess what percentage of the general and youth-targeted adult population approached outside of a convenience/liquor store will agree to purchase and then provide alcohol to individuals who appear under age 21. We conducted 2 waves of pseudo-underage shoulder tap request attempts, using requesters who were age 21 or older but appeared 18 to 20 years old. In both waves, requests were conducted at randomly selected liquor and convenience stores, requesters explained that the reason they were asking the adult was because they did not have their identification with them, and requesters asked the adults to purchase a 6-pack of beer. During wave 1, we conducted 102 attempts, with the requester approaching the first adult entering the store alone. During wave 2, we conducted 102 attempts where the requester approached the first casually dressed male entering the store alone who appeared to be 21 to 30 years old. During wave 1, 8% of the general sample of approached adults provided alcohol to the pseudo-underage requesters. The odds of adults providing alcohol in urban areas were 9.4 times greater than in suburban areas. During wave 2, 19% of the approached young men provided alcohol to the requesters. No requester, request attempt, establishment, or community characteristics were associated with request attempt outcomes during wave 2. A small percentage of the general population of adults will agree to provide alcohol to underage youth when approached outside an alcohol establishment. The likelihood of underage youth obtaining alcohol through shoulder tapping increases substantially if the youth approach young men.

  7. Advanced analysis of finger-tapping performance: a preliminary study.

    Science.gov (United States)

    Barut, Cağatay; Kızıltan, Erhan; Gelir, Ethem; Köktürk, Fürüzan

    2013-06-01

    The finger-tapping test is a commonly employed quantitative assessment tool used to measure motor performance in the upper extremities. This task is a complex motion that is affected by external stimuli, mood and health status. The complexity of this task is difficult to explain with a single average intertap-interval value (time difference between successive tappings) which only provides general information and neglects the temporal effects of the aforementioned factors. This study evaluated the time course of average intertap-interval values and the patterns of variation in both the right and left hands of right-handed subjects using a computer-based finger-tapping system. Cross sectional study. Thirty eight male individuals aged between 20 and 28 years (Mean±SD = 22.24±1.65) participated in the study. Participants were asked to perform single-finger-tapping test for 10 seconds of test period. Only the results of right-handed (RH) 35 participants were considered in this study. The test records the time of tapping and saves data as the time difference between successive tappings for further analysis. The average number of tappings and the temporal fluctuation patterns of the intertap-intervals were calculated and compared. The variations in the intertap-interval were evaluated with the best curve fit method. An average tapping speed or tapping rate can reliably be defined for a single-finger tapping test by analysing the graphically presented data of the number of tappings within the test period. However, a different presentation of the same data, namely the intertap-interval values, shows temporal variation as the number of tapping increases. Curve fitting applications indicate that the variation has a biphasic nature. The measures obtained in this study reflect the complex nature of the finger-tapping task and are suggested to provide reliable information regarding hand performance. Moreover, the equation reflects both the variations in and the general

  8. TAP 2: Performance-Based Training Manual

    International Nuclear Information System (INIS)

    1993-08-01

    Cornerstone of safe operation of DOE nuclear facilities is personnel performing day-to-day functions which accomplish the facility mission. Performance-based training is fundamental to the safe operation. This manual has been developed to support the Training Accreditation Program (TAP) and assist contractors in efforts to develop performance-based training programs. It provides contractors with narrative procedures on performance-based training that can be modified and incorporated for facility-specific application. It is divided into sections dealing with analysis, design, development, implementation, and evaluation

  9. Tapping methane hydrates for unconventional natural gas

    Science.gov (United States)

    Ruppel, Carolyn

    2007-01-01

    Methane hydrate is an icelike form of concentrated methane and water found in the sediments of permafrost regions and marine continental margins at depths far shallower than conventional oil and gas. Despite their relative accessibility and widespread occurrence, methane hydrates have never been tapped to meet increasing global energy demands. With rising natural gas prices, production from these unconventional gas deposits is becoming economically viable, particularly in permafrost areas already being exploited for conventional oil and gas. This article provides an overview of gas hydrate occurrence, resource assessment, exploration, production technologies, renewability, and future challenges.

  10. Tapping polyrhythms in music activates language areas.

    Science.gov (United States)

    Vuust, Peter; Wallentin, Mikkel; Mouridsen, Kim; Ostergaard, Leif; Roepstorff, Andreas

    2011-05-02

    Music is experienced and understood on the basis of foreground/background relationships and tension created between actual music and the underlying meter. Polyrhythms create tension between a counter meter and the main meter. Previously, we have shown that Brodmann area 47 (BA47), a brain area associated with processing of language, is activated bilaterally when musicians tap the main meter in a polymetric context emphasizing a counter meter, suggesting that processing of metric elements in music relies on brain areas also involved in language processing. In that study, the tension was created entirely by changes in the stimulus while participants were tapping the main meter. Here we find left-hemispheric BA47 activation in response to a self-produced counter meter on top of a main meter provided by an ecological music excerpt. This data indicates that the activation is linked to polyrhythmic tension, regardless of whether it arises from the stimulus or the task. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  11. Vaccination and the TAP-independent antigen processing pathways.

    Science.gov (United States)

    López, Daniel; Lorente, Elena; Barriga, Alejandro; Johnstone, Carolina; Mir, Carmen

    2013-09-01

    The cytotoxic CD8(+) T lymphocyte-mediated cellular response is important for the elimination of virus-infected cells and requires the prior recognition of short viral peptide antigens previously translocated to the endoplasmic reticulum by the transporter associated with antigen processing (TAP). However, individuals with nonfunctional TAP complexes or infected cells with TAP molecules blocked by specific viral proteins, such as the cowpoxvirus, a component of the first source of early empirical vaccination against smallpox, are still able to present several HLA class I ligands generated by the TAP-independent antigen processing pathways to specific cytotoxic CD8(+) T lymphocytes. Currently, bioterrorism and emerging infectious diseases have renewed interest in poxviruses. Recent works that have identified HLA class I ligands and epitopes in virus-infected TAP-deficient cells have implications for the study of both the effectiveness of early empirical vaccination and the analysis of HLA class I antigen processing in TAP-deficient subjects.

  12. Dynamical TAP equations for non-equilibrium Ising spin glasses

    DEFF Research Database (Denmark)

    Roudi, Yasser; Hertz, John

    2011-01-01

    We derive and study dynamical TAP equations for Ising spin glasses obeying both synchronous and asynchronous dynamics using a generating functional approach. The system can have an asymmetric coupling matrix, and the external fields can be time-dependent. In the synchronously updated model, the TAP...... equations take the form of self consistent equations for magnetizations at time t+1, given the magnetizations at time t. In the asynchronously updated model, the TAP equations determine the time derivatives of the magnetizations at each time, again via self consistent equations, given the current values...... of the magnetizations. Numerical simulations suggest that the TAP equations become exact for large systems....

  13. Specific Lipids Modulate the Transporter Associated with Antigen Processing (TAP)

    DEFF Research Database (Denmark)

    Scholz, C.; Parcej, D.; Ejsing, C. S.

    2011-01-01

    and structural analysis of this ATP-binding cassette complex, we established the overexpression of TAP in the methylotrophic yeast Pichia pastoris. Screening of optimal solubilization and purification conditions allowed the isolation of the heterodimeric transport complex, yielding 30 mg of TAP/liter of culture....... Detailed analysis of TAP function in the membrane, solubilized, purified, and reconstituted states revealed a direct influence of the native lipid environment on activity. TAP-associated phospholipids, essential for function, were profiled by liquid chromatography Fourier transform mass spectrometry...

  14. The distribution and tapping tidal energy

    Directory of Open Access Journals (Sweden)

    Zygmunt Kowalik

    2004-09-01

    Full Text Available Tidal power along tidal shores has been used for centuries to run small tidal mills. Generating electricity by tapping tidal power proved to be very successful only in the last century through the tidal power plant constructed in 1967 in La Rance, France. This used a large barrier to generate the sea level head necessary for driving turbines. Construction of such plants evolved very slowly because of prohibitive costs and concerns about the environmental impact. Developments in the construction of small, efficient and inexpensive underwater turbines admit the possibility of small scale operations that will use local tidal currents to bring electricity to remote locations. Since the generation of such electricity is concerned with the tidal energy in local water bodies, it is important to understand the site-specific energy balance, i.e., the energy flowing in through open boundaries, and the energy generated and dissipated within the local domain. The question is how to tap the tidal energy while keeping possible changes in the present tidal regimes to a minimum. The older approach of constructing barrages may still be quite useful in some locations. The basics of such tidal power plants constructed in a small bay are analyzed in order to understand the principal parameter for tidal plant evaluation, i.e., the power produced.     The new approach is to place turbines - devices similar to windmills - in the pathway of tidal currents. Theoretically, the amount of power available by such turbines for electricity generation is proportional to the water density and velocity cubed of the tidal flow. The naturally dissipated tidal power due to bottom friction forces is also proportional to the cube of the velocity. Because of this similarity, the exploitation of tidal energy can be directed to reinvesting the naturally dissipated power into tidal power for the generation of electricity. This approach to tidal power exploitation is better tuned

  15. Assessment of leg muscle activity using toe tapping in patients with Parkinson's disease: comparison of two types of toe tapping.

    Science.gov (United States)

    Taniguchi, Seira; Peper, Ferdinand; Shimokawa, Tetsuya

    2018-05-01

    [Purpose] This study investigates two types of toe tapping, i.e., "closed," with both feet on the floor, and "open," in which the foot does not touch the ground, and evaluates their usefulness in combination with monitoring of muscle activity during toe tapping. [Subjects and Methods] The study enrolled 11 patients with Parkinson's disease (PD) and 9 controls (Controls). The tibialis anterior (TA) and gastrocnemius (GS) muscle activity during toe tapping was measured using surface electromyography. [Results] In closed tapping, the minima in GS activation with the first tap was significantly higher in patients with PD than in Controls. In open tapping, the coefficient of variation (CV) of local maxima in TA activation was significantly higher in patients with PD than in Controls. In both types of tapping, the CV of extrema in GS activities increased with disease duration, but this may be due to the long-term administration of Levodopa, which itself tends to cause excessive GS activities. [Conclusion] Closed tapping is suitable for the assessment of GS activity and can detect excessive activities, which is observed as visible movement. Open tapping, on the other hand, is suitable for assessment of TA activity.

  16. Tapping generalized essentialism to predict outgroup prejudices.

    Science.gov (United States)

    Hodson, Gordon; Skorska, Malvina N

    2015-06-01

    Psychological essentialism, the perception that groups possess inherent properties binding them and differentiating them from others, is theoretically relevant to predicting prejudice. Recent developments isolate two key dimensions: essentialistic entitativity (EE; groups as unitary, whole, entity-like) and essentialistic naturalness (EN; groups as fixed and immutable). We introduce a novel question: does tapping the covariance between EE and EN, rather than pitting them against each other, boost prejudice prediction? In Study 1 (re-analysis of Roets & Van Hiel, 2011b, Samples 1-3, in Belgium) and Study 2 (new Canadian data) their common/shared variance, modelled as generalized essentialism, doubles the predictive power relative to regression-based approaches with regard to racism (but not anti-gay or -schizophrenic prejudices). Theoretical implications are discussed. © 2014 The British Psychological Society.

  17. Creep collapse of TAPS fuel cladding

    International Nuclear Information System (INIS)

    Chaudhry, S.M.; Anand, A.K.

    1975-01-01

    Densification of UO 2 can cause axial gaps between fuel pelets and cladding in unsupported (internally) at these regions. An analysis is carried out regarding the possibility of creep collapse in these regions. The analysis is based on Timoshenko's theory of collapse. At various times during the residence of fuel in reactor following parameters are calculated : (1) inelastic collapse of perfectly circular tubes (2) plastic instability in oval tubes (3) effect of creep on ovality. Creep is considered to be a non-linear combination of the following : (a) thermal creep (b) intresenic creep (c) stress aided radiation enhanced (d) stress free growth (4) Critical pressure ratio. The results obtained are compared with G.E. predictions. The results do not predict collapse of TAPS fuel cladding for five year residence time. (author)

  18. The Expanding Universe of Astronomy on Tap

    Science.gov (United States)

    Livermore, Rachael C.; Morris, Brett; Narayan, Gautham; Morrison, Sarah J.; Schneider, Evan; Bozek, Brandon; Rice, Emily L.; Hummels, Cameron B.; Garofali, Kristen; Martinez, Raquel; Li, Yuan; Green, Joel D.; LaMassa, Stephanie M.; Silvia, Devin W.; Schwamb, Megan E.; Arcavi, Iair; Silverman, Jeffrey M.

    2017-01-01

    Astronomy on Tap (AoT) is a constellation of free public outreach presentations held in bars. AoT events aim to engage audiences who might not choose to attend public lectures in a university setting by creating an informal atmosphere and combining scientific talks with music, games, and prizes. The events have a flexible format, typically consisting of between one and three astronomy-related presentations, sometimes with additional games and trivia, and some locations also produce merchandise. The flexible structure means that the format can be adapted to the resources available in the location and the time commitment the local organizers are willing to make. Some events are broadcast online through live streaming, with some others being posted to YouTube. In conjunction with an active social media presence, this ensures engagement beyond those able to attend events in person. Astronomy on Tap events have now been held in 20 cities around the world and are typically organised by postdocs and graduate students, with some involvement from faculty and outreach or education staff. Holding these events under the global AoT constellation facilitates knowledge transfer, sharing of resources, and networking opportunities for scientists interested in outreach/communication. The events have been highly successful, with some locations regularly attracting more than 200 people per month. In this poster we describe the goals and characteristics of AoT events, the different adaptations by various locations, the resources we have developed, and provide information for those interested in starting a new event in their location.

  19. Tap Testing Hammer using Unmanned Aerial Systems (UASs)

    Energy Technology Data Exchange (ETDEWEB)

    Mason, JaMein DeShon [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ayorinde, Emmanuel Temiloluwa [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mascarenas, David Dennis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Moreu, Fernando [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Univ. of New Mexico, Albuquerque, NM (United States)

    2016-08-11

    This is the final poster for a Student Symposium at Los Alamos National Laboratory. This research describes the development, validation, and testing of a remote concrete tapping mechanism enabled by UAS. The conclusion is the following: The results quantify for the first time concrete tapping data collected remotely with UAS, enabling cost-effective, safer and sustainable upgrade prioritization of railroad bridges inventories.

  20. Sequential and Biomechanical Factors Constrain Timing and Motion in Tapping

    NARCIS (Netherlands)

    Loehr, J.D.; Palmer, C.

    2009-01-01

    The authors examined how timing accuracy in tapping sequences is influenced by sequential effects of preceding finger movements and biomechanical interdependencies among fingers. Skilled pianists tapped Sequences at 3 rates; in each sequence, a finger whose motion was more or less independent of

  1. Local Identification of Voltage Instability from Load Tap Changer Response

    DEFF Research Database (Denmark)

    Weckesser, Johannes Tilman Gabriel; Papangelis, Lampros; Vournas, Costas D.

    2017-01-01

    . The new method is not bound to assessing system response over a predefined LTC tapping period. This allows handling LTCs with variable delays, as well as events taking place during the tapping sequence impacting the distribution voltages. For that purpose, eLIVES applies recursive least square fitting...

  2. Tap Water Hydraulic Systems for Medium Power Applications

    DEFF Research Database (Denmark)

    Conrad, Finn; Adelstorp, Anders

    1998-01-01

    Presentation of new range of developed tap water hydraulic componets and applications for medium power up to 4 kW and 50 bar.......Presentation of new range of developed tap water hydraulic componets and applications for medium power up to 4 kW and 50 bar....

  3. Hydraulic Systems with Tap Water versus Bio-oils

    DEFF Research Database (Denmark)

    Conrad, Finn

    1997-01-01

    Deals with the advantages of using pure tap water hydraulics versus bio-oils for suiteable applications. Focus is in particular on food processing industry.......Deals with the advantages of using pure tap water hydraulics versus bio-oils for suiteable applications. Focus is in particular on food processing industry....

  4. Role of attractive forces in tapping tip force microscopy

    DEFF Research Database (Denmark)

    Kyhle, Anders; Sørensen, Alexis Hammer; Bohr, Jakob

    1997-01-01

    We present experimental and numerical results demonstrating the drastic influence of attractive forces on the behaviour of the atomic force microscope when operated in the resonant tapping tip mode in an ambient environment. It is often assumed that tapping is related to repulsive interaction...

  5. Abstract: Trauma Tapping Technique: Practical First Aid for Stress ...

    African Journals Online (AJOL)

    Trauma tapping technique (TTT) is a procedure that uses touch through tapping to relieve anxiety symptoms. TTT is a nonverbal process that can be delivered at minimal cost with the potential for easy dissemination. This technique can be applied in urban or rural communities and in medical or mental health environments.

  6. Real time kernel performance monitoring with SystemTap

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    SystemTap is a dynamic method of monitoring and tracing the operation of a running Linux kernel. In this talk I will present a few practical use cases where SystemTap allowed me to turn otherwise complex userland monitoring tasks in simple kernel probes.

  7. A Dynamic Tap Allocation for Concurrent CMA-DD Equalizers

    Directory of Open Access Journals (Sweden)

    Trindade DiegovonBM

    2010-01-01

    Full Text Available Abstract This paper proposes a dynamic tap allocation for the concurrent CMA-DD equalizer as a low complexity solution for the blind channel deconvolution problem. The number of taps is a crucial factor which affects the performance and the complexity of most adaptive equalizers. Generally an equalizer requires a large number of taps in order to cope with long delays in the channel multipath profile. Simulations show that the proposed new blind equalizer is able to solve the blind channel deconvolution problem with a specified and reduced number of active taps. As a result, it minimizes the output excess mean square error due to inactive taps during and after the equalizer convergence and the hardware complexity as well.

  8. Frankincense tapping reduces the carbohydrate storage of Boswellia trees.

    Science.gov (United States)

    Mengistu, Tefera; Sterck, Frank J; Fetene, Masresha; Bongers, Frans

    2013-06-01

    Carbohydrates fixed by photosynthesis are stored in plant organs in the form of starch or sugars. Starch and sugars sum to the total non-structural carbohydrate pool (TNC) and may serve as intermediate pools between assimilation and utilization. We examined the impact of tapping on TNC concentrations in stem-wood, bark and root tissues of the frankincense tree (Boswellia papyrifera (Del.) Hochst) in two natural woodlands of Ethiopia. Two tapping treatments, one without tapping (control) and the other with tapping at 12 incisions, are applied on experimental trees. Trees are tapped in the leafless dry period, diminishing their carbon storage pools. If storage pools are not refilled by assimilation during the wet season, when crowns are in full leaf, tapping may deplete the carbon pool and weaken Boswellia trees. The highest soluble sugar concentrations were in the bark and the highest starch concentrations in the stem-wood. The stem-wood contains 12 times higher starch than soluble sugar concentrations. Hence, the highest TNC concentrations occurred in the stem-wood. Moreover, wood volume was larger than root or bark volumes and, as a result, more TNC was stored in the stem-wood. As predicted, tapping reduced the TNC concentrations and pool sizes in frankincense trees during the dry season. During the wet season, these carbon pools were gradually filled in tapped trees, but never to the size of non-tapped trees. We conclude that TNC is dynamic on a seasonal time scale and offers resilience against stress, highlighting its importance for tree carbon balance. But current resin tapping practices are intensive and may weaken Boswellia populations, jeopardizing future frankincense production.

  9. TAP Report - Southwest Idaho Juniper Working Group

    Energy Technology Data Exchange (ETDEWEB)

    Gresham, Garold Linn [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    There is explicit need for characterization of the materials for possible commercialization as little characterization data exists. Pinyon-juniper woodlands are a major ecosystem type found in the Southwest and the Intermountain West regions of the United States including Nevada, Idaho and Oregon. These widespread ecosystems are characterized by the presence of several different species of pinyon and juniper as the dominant plant cover. Since the 1800s, pinyon-juniper woodlands have rapidly expanded their range at the expense of existing ecosystems. Additionally, existing woodlands have become denser, progressively creating potential fire hazards as seen in the Soda Fire, which burned more than 400 sq. miles. Land managers responsible for these areas often desire to reduce pinyon-juniper coverage on their lands for a variety of reasons, as stated in the Working Group objectives. However, the cost of clearing thinning pinyon-juniper stands can be prohibitive. One reason for this is the lack of utilization options for the resulting biomass that could help recover some of the cost of pinyon-juniper stand management. The goal of this TAP effort was to assess the feedstock characteristics of biomass from a juniper harvested from Owyhee County to evaluate possible fuel and conversion utilization options.

  10. The neural substrates of impaired finger tapping regularity after stroke.

    Science.gov (United States)

    Calautti, Cinzia; Jones, P Simon; Guincestre, Jean-Yves; Naccarato, Marcello; Sharma, Nikhil; Day, Diana J; Carpenter, T Adrian; Warburton, Elizabeth A; Baron, Jean-Claude

    2010-03-01

    Not only finger tapping speed, but also tapping regularity can be impaired after stroke, contributing to reduced dexterity. The neural substrates of impaired tapping regularity after stroke are unknown. Previous work suggests damage to the dorsal premotor cortex (PMd) and prefrontal cortex (PFCx) affects externally-cued hand movement. We tested the hypothesis that these two areas are involved in impaired post-stroke tapping regularity. In 19 right-handed patients (15 men/4 women; age 45-80 years; purely subcortical in 16) partially to fully recovered from hemiparetic stroke, tri-axial accelerometric quantitative assessment of tapping regularity and BOLD fMRI were obtained during fixed-rate auditory-cued index-thumb tapping, in a single session 10-230 days after stroke. A strong random-effect correlation between tapping regularity index and fMRI signal was found in contralesional PMd such that the worse the regularity the stronger the activation. A significant correlation in the opposite direction was also present within contralesional PFCx. Both correlations were maintained if maximal index tapping speed, degree of paresis and time since stroke were added as potential confounds. Thus, the contralesional PMd and PFCx appear to be involved in the impaired ability of stroke patients to fingertap in pace with external cues. The findings for PMd are consistent with repetitive TMS investigations in stroke suggesting a role for this area in affected-hand movement timing. The inverse relationship with tapping regularity observed for the PFCx and the PMd suggests these two anatomically-connected areas negatively co-operate. These findings have implications for understanding the disruption and reorganization of the motor systems after stroke. Copyright (c) 2009 Elsevier Inc. All rights reserved.

  11. Finger tapping ability in healthy elderly and young adults.

    Science.gov (United States)

    Aoki, Tomoko; Fukuoka, Yoshiyuki

    2010-03-01

    The maximum isometric force production capacity of the fingers decreases with age. However, little information is available on age-related changes in dynamic motor capacity of individual fingers. The purpose of this study was to compare the dynamic motor function of individual fingers between elderly and young adults using rapid single-finger and double-finger tapping. Fourteen elderly and 14 young adults performed maximum frequency tapping by the index, middle, ring, or little finger (single-finger tapping) and with alternate movements of the index-middle, middle-ring, or ring-little finger-pair (double-finger tapping). The maximum pinch force between the thumb and each finger, tactile sensitivity of each fingertip, and time taken to complete a pegboard test were also measured. Compared with young subjects, the older subjects had significantly slower tapping rates in all fingers and finger-pairs in the tapping tasks. The age-related decline was also observed in the tactile sensitivities of all fingers and in the pegboard test. However, there was no group difference in the pinch force of any finger. The tapping rate of each finger did not correlate with the pinch force or tactile sensitivity for the corresponding finger in the elderly subjects. Maximum rate of finger tapping was lower in the elderly adults compared with the young adults. The decline of finger tapping ability in elderly adults seems to be less affected by their maximum force production capacities of the fingers as well as tactile sensitivities at the tips of the fingers.

  12. Analgesic effect of bilateral subcostal tap block after laparoscopic cholecystectomy

    International Nuclear Information System (INIS)

    Karam, K.; Khan, B.I.

    2018-01-01

    Pain after laparoscopic cholecystectomy is mild to moderate in intensity. Several modalities are employed for achieving safe and effective postoperative analgesia, the benefits of which adds to the early recovery of the patients. As a part of multimodal analgesia, various approaches of Transversus abdominis plane (TAP) block has been used for management of parietal and incisional components of pain after laparoscopic cholecystectomy. This study was designed to compare the analgesic efficacy of two different approaches of ultrasound guided TAP block, i.e., Subcostal-TAP block technique with ultrasound guided Posterior-TAP block for post-operative pain management in patients undergoing laparoscopic cholecystectomy under general anaesthesia. Methods: In this double blinded randomized controlled study, consecutive nonprobability sampling was done and a total of 126 patients admitted for elective laparoscopic cholecystectomy fulfilling the inclusion criteria were selected. After induction of general anaesthesia, patients were randomized through draw method and received either ultrasound guided posterior TAP block with 0.375% bupivacaine (20ml volume) on each side of the abdomen or subcostal TAP block bilaterally with the same. Up to 24 hours postoperatively, static and dynamic numeric rating pain scores were assessed. Results: We found statistically significant difference in mean static pain scores over 24 hours postoperatively in subcostal TAP group, suggesting improved analgesia. However, mean dynamic postoperative pain scores were comparable between the two groups. Whereas, patients in both groups were satisfied with pain management. Conclusions: Ultrasound guided subcostal TAP block provides better postoperative analgesia as compared to the Posterior TAP block in laparoscopic cholecystectomy. Otherwise both of the approaches improve patient outcomes towards early recovery and discharge from hospital. (author)

  13. Experimental Study on Environment Friendly Tap Hole Clay for Blast Furnace

    Science.gov (United States)

    Siva kumar, R.; Mohammed, Raffi; Srinivasa Rao, K.

    2018-03-01

    Blast furnace (BF) is the best possible route of iron production available. Blast furnace is a high pressure vessel where iron ore is melted and liquid iron is produced. The liquid iron is tapped through the hole in Blast Furnace called tap hole. The tapped liquid metal flowing through the tap hole is plugged using a clay called tap hole clay. Tap hole clay (THC) is a unshaped refractory used to plug the tap hole. The tap hole clay extruded through the tap hole using a gun. The tap hole clay is designed to expand and plug the tap hole. The tap hole filled with clay is drilled using drill bit and the hole made through the tap hole to tap the liquid metal accumulated inside the furnace. The number of plugging and drilling varies depending on the volume of the furnace. The tap hole clay need to have certain properties to avoid problems during plugging and drilling. In the present paper tap hole clay properties in industrial use was tested and studied. The problems were identified related to tap hole clay manufacturing. Experiments were conducted in lab scale to solve the identified problems. The present composition was modified with experimental results. The properties of the modified tap hole clay were found suitable and useful for blast furnace operation with lab scale experimental results.

  14. Beer tapping: dynamics of bubbles after impact

    Science.gov (United States)

    Mantič-Lugo, V.; Cayron, A.; Brun, P.-T.; Gallaire, F.

    2015-12-01

    Beer tapping is a well known prank where a bottle of beer is impacted from the top by a solid object, usually another bottle, leading to a sudden foam overflow. A description of the shock-driven bubble dynamics leading to foaming is presented based on an experimental and numerical study evoking the following physical picture. First, the solid impact produces a sudden downwards acceleration of the bottle creating a strong depression in the liquid bulk. The existing bubbles undergo a strong expansion and a sudden contraction ending in their collapse and fragmentation into a large amount of small bubbles. Second, the bubble clouds present a large surface area to volume ratio, enhancing the CO2 diffusion from the supersaturated liquid, hence growing rapidly and depleting the CO2. The clouds of bubbles migrate upwards in the form of plumes pulling the surrounding liquid with them and eventually resulting in the foam overflow. The sudden pressure drop that triggers the bubble dynamics with a collapse and oscillations is modelled by the Rayleigh-Plesset equation. The bubble dynamics from impact to collapse occurs over a time (tb ≃ 800 μs) much larger than the acoustic time scale of the liquid bulk (tac = 2H/c ≃ 80 μs), for the experimental container of height H = 6 cm and a speed of sound around c ≃ 1500 m/s. This scale separation, together with the comparison of numerical and experimental results, suggests that the pressure drop is controlled by two parameters: the acceleration of the container and the distance from the bubble to the free surface.

  15. Astronomy on Tap: science engagement in the pub

    Science.gov (United States)

    Livermore, Rachael C.; Silverman, Jeffrey Michael

    2015-08-01

    Astronomy on Tap is a series of free lectures by astronomers in the pub, aimed at disseminating the latest research to the public in an informal setting. Started in New York City in 2013, Astronomy on Tap has now expanded to seven cities across North and South America. Organized by local astronomers, each event features talks by astronomers from local institutions or visitors, or others whose professions or hobbies intersect with astronomy, along with games and opportunities for the public to interact with professional astronomers. The largest Astronomy on Tap events are in Austin, Texas, attracting over 150 people each month, which consists of populations outside of the self-selected groups that might be reached by more formal EPO activities. The organisers of Astronomy on Tap in Austin (AoTATX) will discuss the impact of and feedback from all of the locations, and present information on setting up new satellite locations.

  16. Trauma Tapping Technique: Practical First Aid for Stress and Trauma

    African Journals Online (AJOL)

    Epidemiological studies on posttraumatic stress disorder (PTSD) show a lifetime ... include re-experiencing the traumatic event, avoidant behavior for the memories of ... Methods. Trauma tapping technique (TTT) is a procedure that uses touch ...

  17. Finger and foot tapping sensor system for objective motor assessment

    Directory of Open Access Journals (Sweden)

    Đurić-Jovičić Milica

    2018-01-01

    Full Text Available Background/Aim. Finger tapping test is commonly used in neurological examinations as a test of motor performance. The new system comprising inertial and force sensors and custom proprietary software was developed for quantitative estimation and assessment of finger and foot tapping tests. The aim of this system was to provide diagnosis support and objective assessment of motor function. Methods. Miniature inertial sensors were placed on fingertips and used for measuring finger movements. A force sensor was placed on the fingertip of one finger, in order to measure the force during tapping. For foot tapping assessment, an inertial sensor was mounted on the subject’s foot, which was placed above a force platform. By using this system, various parameters such as a number of taps, tapping duration, rhythm, open and close speed, the applied force and tapping angle, can be extracted for detailed analysis of a patient’s motor performance. The system was tested on 13 patients with Parkinson’s disease and 14 healthy controls. Results. The system allowed easy measurement of listed parameters, and additional graphical representation showed quantitative differences in these parameters between neurological patient and healthy subjects. Conclusion. The novel system for finger and foot tapping test is compact, simple to use and efficiently collects patient data. Parameters measured in patients can be compared to those measured in healthy subjects, or among groups of patients, or used to monitor progress of the disease, or therapy effects. Created data and scores could be used together with the scores from clinical tests, providing the possibility for better insight into the diagnosis. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 175090 and Grant no. 175016

  18. [The method to remove nitrite from tap water by tea].

    Science.gov (United States)

    Lu, M; Chen, L; Xian, H

    1997-03-01

    Drinking water (tap water) is polluted in pipelines by bacteria after long distance transportation. The water contains nitrite (NO2-) which is potentially harmful to human health. The nitrite concentrations range from 0.10 to 2.0 mg/L. Our experiment proved that NO2- could not be removed by boiling, but could be removed by tea. As a natural antioxidant, tea contains several antioxidants, such as ascorbic acid and catechins, which removed NO2- from tap water effectively.

  19. Quantification of Finger-Tapping Angle Based on Wearable Sensors.

    Science.gov (United States)

    Djurić-Jovičić, Milica; Jovičić, Nenad S; Roby-Brami, Agnes; Popović, Mirjana B; Kostić, Vladimir S; Djordjević, Antonije R

    2017-01-25

    We propose a novel simple method for quantitative and qualitative finger-tapping assessment based on miniature inertial sensors (3D gyroscopes) placed on the thumb and index-finger. We propose a simplified description of the finger tapping by using a single angle, describing rotation around a dominant axis. The method was verified on twelve subjects, who performed various tapping tasks, mimicking impaired patterns. The obtained tapping angles were compared with results of a motion capture camera system, demonstrating excellent accuracy. The root-mean-square (RMS) error between the two sets of data is, on average, below 4°, and the intraclass correlation coefficient is, on average, greater than 0.972. Data obtained by the proposed method may be used together with scores from clinical tests to enable a better diagnostic. Along with hardware simplicity, this makes the proposed method a promising candidate for use in clinical practice. Furthermore, our definition of the tapping angle can be applied to all tapping assessment systems.

  20. Effectiveness of hand washing on the removal of iron oxide nanoparticles from human skin ex vivo.

    Science.gov (United States)

    Lewinski, Nastassja A; Berthet, Aurélie; Maurizi, Lionel; Eisenbeis, Antoine; Hopf, Nancy B

    2017-08-01

    In this study, the effectiveness of washing with soap and water in removing nanoparticles from exposed skin was investigated. Dry, nanoscale hematite (α-Fe 2 O 3 ) or maghemite (γ-Fe 2 O 3 ) powder, with primary particle diameters between 20-30 nm, were applied to two samples each of fresh and frozen ex vivo human skin in two independent experiments. The permeation of nanoparticles through skin, and the removal of nanoparticles after washing with soap and water were investigated. Bare iron oxide nanoparticles remained primarily on the surface of the skin, without penetrating beyond the stratum corneum. Skin exposed to iron oxide nanoparticles for 1 and 20 hr resulted in removal of 85% and 90%, respectively, of the original dose after washing. In the event of dermal exposure to chemicals, removal is essential to avoid potential local irritation or permeation across skin. Although manufactured at an industrial scale and used extensively in laboratory experiments, limited data are available on the removal of engineered nanoparticles after skin contact. Our finding raises questions about the potential consequences of nanoparticles remaining on the skin and whether alternative washing methods should be proposed. Further studies on skin decontamination beyond use of soap and water are needed to improve the understanding of the potential health consequences of dermal exposure to nanoparticles.

  1. Evaluation of primary stability of self-tapping and non-self-tapping dental implants. A 12-week clinical study.

    Science.gov (United States)

    Marković, Aleksa; Calvo-Guirado, José Luís; Lazić, Zoran; Gómez-Moreno, Gerardo; Ćalasan, Dejan; Guardia, Javier; Čolic, Snježana; Aguilar-Salvatierra, Antonio; Gačić, Bojan; Delgado-Ruiz, Rafael; Janjić, Bojan; Mišić, Tijana

    2013-06-01

    The aim of this study was to investigate the relationship between surgical techniques and implant macro-design (self-tapping/non-self-tapping) for the optimization of implant stability in the low-density bone present in the posterior maxilla using resonance frequency analysis (RFA). A total of 102 implants were studied. Fifty-six self-tapping BlueSkyBredent® (Bredent GmbH&Co.Kg®, Senden, Germany) and 56 non-self-tapping Standard Plus Straumann® (Institut Straumann AG®, Waldenburg, Switzerland) were placed in the posterior segment of the maxilla. Implants of both types were placed in sites prepared with either lateral bone-condensing or with bone-drilling techniques. Implant stability measurements were performed using RFA immediately after implant placement and weekly during a 12-week follow-up period. Both types of implants placed after bone condensing achieved significantly higher stability immediately after surgery, as well as during the entire 12-week observation period compared with those placed following bone drilling. After bone condensation, there were no significant differences in primary stability or in implant stability after the first week between both implant types. From 2 to 12 postoperative weeks, significantly higher stability was shown by self-tapping implants. After bone drilling, self-tapping implants achieved significantly higher stability than non-self-tapping implants during the entire follow-up period. The outcomes of the present study indicate that bone drilling is not an effective technique for improving implant stability and, following this technique, the use of self-tapping implants is highly recommended. Implant stability optimization in the soft bone can be achieved by lateral bone-condensing technique, regardless of implant macro-design. © 2011 Wiley Periodicals, Inc.

  2. Probing and Tapping: Are We Inserting Pedicle Screws Correctly?

    Science.gov (United States)

    Prasad, Vishal; Mesfin, Addisu; Lee, Robert; Reigrut, Julie; Schmidt, John

    2016-11-01

    Although there are a significant number of research publications on the topic of bone morphology and the strength of bone, the clinical significance of a failed pedicle screw is often revision surgery and the potential for further postoperative complications; especially in elderly patients with osteoporotic bone. The purpose of this report is to quantify the mechanical strength of the foam-screw interface by assessing probe/pilot hole diameter and tap sizes using statistically relevant sample sizes under highly controlled test conditions. The study consisted of two experiments and used up to three different densities of reference-grade polyurethane foam (ASTM 1839), including 0.16, 0.24, and 0.32 g/cm 3 . All screws and rods were provided by K2M Inc. and screws were inserted to a depth of 25 mm. A series of pilot holes, 1.5, 2.2, 2.7, 3.2, 3.7, 4.2, 5.0, and 6.0 mm in diameter were drilled through the entire depth of the material. A 6.5 × 45-mm pedicle screw was inserted and axially pulled from the material (n = 720). A 3.0-mm pilot hole was drilled and tapped with: no tap, 3.5-, 4.5-, 5.5-, and 6.5-mm taps. A 6.5 × 45-mm pedicle screw was inserted and axially pulled from the material (n = 300). The size of the probe/pilot hole had a nonlinear, parabolic effect on pullout strength. This shape suggests an optimum-sized probe hole for a given size pedicle screw. Too large or too small of a probe hole causes a rapid falloff in pullout strength. The tap data demonstrated that not tapping and undertapping by two or three sizes did not significantly alter the pullout strength of the screws. The data showed an exponential falloff of pullout strength when as tap size increased to the diameter of the screw. In the current study, the data show that an ideal pilot hole size half the diameter of the screw is a starting point. Also, that if tapping was necessary, to use a tap two sizes smaller than the screw being implanted. A similar optimum pilot hole or tap size may be

  3. Beam polarimetry in the CBELSA/TAPS experiment; Strahlpolarimetrie am CBELSA/TAPS Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Kammer, Susanne

    2010-02-19

    In the identification of nucleon resonances polarization observables play an important role. For the photoproduction experiments of the CBELAS/TAPS assembly at the accelerator facility ELSA in the framework of this thesis linearly and circularly polarized were realized and prepared. Linearly polarized photons were produced on a diamond crystal under usage of the coherent bremsstrahlung. By alignment of the crystal in the bremsstrahlung coherent intensity increasements in form of pronounced edges could be generated. The number of the polarized photons lying in the increasement determines in comparison to the incoherently produced background the degree of polarization. The position of the coherent edge could be tuned by means of control distributions to an arbitrary position in the measured energy spectrum as well as the degree of polarization of the photons optimized. For the production of circularly polarized photons longitudinally polarized electrons on the bremsstrahlung target are required. The polarization transfer of the bremsstrahlung process is uniquely given by the QED, so that the degree of polarization of the photons can be determined via a measurement of the electron-beam polarization. With this goal a for the first time in the CBELSA/TAPS applied momentum-selecting Moeller polarimeter was developed and integrated in the photon-tagging facility. Via a change of the beam helicity the counting-rate asymmetry for parallely and antiparallely beam and target electrons was measured and the degree of polarization of the electrons at beam energies of 2350 MeV determined to typically above 60%. By means of dedicated test measurements and simulations the functionality of the Moeller polarimeter was checked and the relative systematic uncertainty determined to 1%. Since 2007 the Moeller polarimeter essential for the double-polarization experiments is in current operation. Finally a method was sketched, in which via the known cross-section asymmetry of the

  4. Computerized measures of finger tapping: reliability, malingering and traumatic brain injury.

    Science.gov (United States)

    Hubel, Kerry A; Yund, E William; Herron, Timothy J; Woods, David L

    2013-01-01

    We analyzed computerized finger tapping metrics in four experiments. Experiment 1 showed tapping-rate differences associated with hand dominance, digits, sex, and fatigue that replicated those seen in a previous, large-scale community sample. Experiment 2 revealed test-retest correlations (r = .91) that exceeded those reported in previous tapping studies. Experiment 3 investigated subjects simulating symptoms of traumatic brain injury (TBI); 62% of malingering subjects produced abnormally slow tapping rates. A tapping-rate malingering index, based on rate-independent tapping patterns, provided confirmatory evidence of malingering in 48% of the subjects with abnormal tapping rates. Experiment 4 compared tapping in 24 patients with mild TBI (mTBI) and a matched control group; mTBI patients showed slowed tapping without evidence of malingering. Computerized finger tapping measures are reliable measures of motor speed, useful in detecting subjects performing with suboptimal effort, and are sensitive to motor abnormalities following mTBI.

  5. Abnormal maximal finger tapping in abstinent cannabis users.

    Science.gov (United States)

    Flavel, Stanley C; White, Jason M; Todd, Gabrielle

    2013-11-01

    To investigate movement speed and rhythmicity in abstinent cannabis users, we hypothesized that abstinent cannabis users exhibit decreased maximal finger tapping frequency and increased variability of tapping compared with non-drug users. The study involved 10 healthy adult cannabis users and 10 age-matched and gender-matched controls with no history of illicit drug use. Subjects underwent a series of screening tests prior to participation. Subjects were then asked to tap a strain gauge as fast as possible with the index finger of their dominant hand (duration 5 s). The average intertap interval did not significantly differ between groups, but the coefficient of variation of the intertap interval was significantly greater in the cannabis group than in controls (p=0.011). The cannabis group also exhibited a slow tapping frequency at the beginning of the task. Rhythmicity of finger tapping is abnormal in individuals with a history of cannabis use. The abnormality appears to be long lasting and adds to the list of functional changes present in abstinent cannabis users. Copyright © 2013 John Wiley & Sons, Ltd.

  6. Multiplication of Legionella pneumophila in unsterilized tap water.

    Science.gov (United States)

    Yee, R B; Wadowsky, R M

    1982-06-01

    Naturally occurring Legionella pneumophila, an environmental isolate which had not been grown on artificial medium, was tested for the ability to multiply in tap water. A showerhead containing L. pneumophila and non-Legionellaceae bacteria was immersed in nonsterile tap water supplying this fixture. Also L. pneumophila and non-Legionellaceae bacteria were sedimented from tap water from a surgical intensive care unit. This bacterial suspension was inoculated into tap water from our laboratory. The legionellae in both suspensions multiplied in the tap water at 32, 37, and 42 degrees C. The non-Legionellaceae bacteria multiplied at 25, 32, and 37 degrees C. A water sample which was collected from the bottom of a hot water tank was found to contain L. pneumophila and non-Legionellaceae bacteria. These legionellae also multiplied when the water sample was incubated at 37 degrees C. These results indicate that L. pneumophila may multiply in warm water environments such as hot water plumbing fixtures, hot water tanks, and cooling towers.

  7. Major inorganic elements in tap water samples in Peninsular Malaysia.

    Science.gov (United States)

    Azrina, A; Khoo, H E; Idris, M A; Amin, I; Razman, M R

    2011-08-01

    Quality drinking water should be free from harmful levels of impurities such as heavy metals and other inorganic elements. Samples of tap water collected from 24 locations in Peninsular Malaysia were determined for inorganic element content. Minerals and heavy metals were analysed by spectroscopy methods, while non-metal elements were analysed using test kits. Minerals and heavy metals determined were sodium, magnesium, potassium, calcium, chromium, manganese, iron, nickel, copper, zinc, arsenic, cadmium and lead while the non-metal elements were fluoride, chloride, nitrate and sulphate. Most of the inorganic elements found in the samples were below the maximum permitted levels recommended by inter-national drinking water standard limits, except for iron and manganese. Iron concentration of tap water from one of the locations was higher than the standard limit. In general, tap water from different parts of Peninsular Malaysia had low concentrations of heavy metals and inorganic elements.

  8. Paired Synchronous Rhythmic Finger Tapping without an External Timing Cue Shows Greater Speed Increases Relative to Those for Solo Tapping.

    Science.gov (United States)

    Okano, Masahiro; Shinya, Masahiro; Kudo, Kazutoshi

    2017-03-09

    In solo synchronization-continuation (SC) tasks, intertap intervals (ITI) are known to drift from the initial tempo. It has been demonstrated that people in paired and group contexts modulate their action timing unconsciously in various situations such as choice reaction tasks, rhythmic body sway, and hand clapping in concerts, which suggests the possibility that ITI drift is also affected by paired context. We conducted solo and paired SC tapping experiments with three tempos (75, 120, and 200 bpm) and examined whether tempo-keeping performance changed according to tempo and/or the number of players. Results indicated that those tapping in the paired conditions were faster, relative to those observed in the solo conditions, for all tempos. For the faster participants, the degree of ITI drift in the solo conditions was strongly correlated with that in the paired conditions. Regression analyses suggested that both faster and slower participants adapted their tap timing to that of their partners. A possible explanation for these results is that the participants reset the phase of their internal clocks according to the faster beat between their own tap and the partners' tap. Our results indicated that paired context could bias the direction of ITI drift toward decreasing.

  9. INDUSTRIAL APPROBATION OF COMBINED COUNTERSINK-TAP TOOL

    Directory of Open Access Journals (Sweden)

    Nurulla M. Vagabov

    2017-01-01

    Full Text Available Abstract. Objectives Based on a critical analysis of the results of complex studies, we set out to demonstrate the advantages, as compared with existing technologies, of a developed technology that uses a new cutting scheme with a combined countersink-tap tool. Methods One way to improve the processing capacity, tool life and quality of a cut thread is to reduce the torque and strain hardening of the processed material by employing a new cutting approach to completely eliminate the friction of the lateral sides of the tooth on the surface of the cut thread. It was necessary for this technology to be checked in real production conditions. Results The conducted production tests of a combined countersink-tap tool with the new cutting scheme developed by the inventors have shown that, as a result of a significant reduction in the torque and a decrease in the strain hardening of the processed material, it is possible to increase the cutting speed and increase labour productivity by more than 2 times as compared with the thread cutting processes using taps with staggered teeth, 1.2 times as compared to taps with a corrected structure, and more than 6 times as compared to standard taps. At the same time, the stability of the tool is increased 3-5 times and the number of breakages is also sharply reduced. Conclusion It has been established that the accuracy of the geometric parameters as well as the strength and quality of the thread surface cut by the combined countersink-tap tool with the new cutting scheme in hard-to-work materials is much higher than the same thread parameters obtained by processing with standard and other known taps. The studies also indicated its high reliability, operability and expediency of application for processing the above-mentioned materials. The advantages of the combined tool also include a reduction in thread cutting time as compared to a separate machining of the threaded hole (countersinking with a standard

  10. Extended topologies of tapped-inductor Z-source inverters

    DEFF Research Database (Denmark)

    Zhu, Miao; Li, Ding; Gao, Feng

    2011-01-01

    In this paper, two distinct types of tapped-inductor Z-source impedance networks are proposed for implementing high performance voltage-type inverters topologies with strong voltage boost inversion abilities and less components' stresses. All proposed topologies can in principle be unified...... into a generic network entity, which is termed hybrid-source tapped-inductor impedance network. The resulting novel Z-source inverters would have a higher output voltage gain and other unique advantages that currently have not yet been investigated. Theoretical analysis for explaining these operating features...

  11. Rhythmic finger tapping reveals cerebellar dysfunction in essential tremor

    NARCIS (Netherlands)

    Buijink, A. W. G.; Broersma, M.; van der Stouwe, A. M. M.; van Wingen, G. A.; Groot, P. F. C.; Speelman, J. D.; Maurits, N. M.; van Rootselaar, A. F.

    Introduction: Cerebellar circuits are hypothesized to play a central role in the pathogenesis of essential tremor. Rhythmic finger tapping is known to strongly engage the cerebellar motor circuitry. We characterize cerebellar and, more specifically, dentate nucleus function, and neural correlates of

  12. Rhythmic finger tapping reveals cerebellar dysfunction in essential tremor

    NARCIS (Netherlands)

    Buijink, A. W. G.; Broersma, M.; van der Stouwe, A. M. M.; van Wingen, G. A.; Groot, P. F. C.; Speelman, J. D.; Maurits, N. M.; van Rootselaar, A. F.

    2015-01-01

    Cerebellar circuits are hypothesized to play a central role in the pathogenesis of essential tremor. Rhythmic finger tapping is known to strongly engage the cerebellar motor circuitry. We characterize cerebellar and, more specifically, dentate nucleus function, and neural correlates of cerebellar

  13. TRIHALOMETHANE LEVELS IN HOME TAP WATER AND SEMEN QUALITY

    Science.gov (United States)

    Trihalomethane Levels in Home Tap Water and Semen QualityLaura Fenster, 1 Kirsten Waller, 2 Gayle Windham, 1 Tanya Henneman, 2 Meredith Anderson, 2 Pauline Mendola, 3 James W. Overstreet, 4 Shanna H. Swan51California Department of Health Services, Division of Environm...

  14. Potential, Distribution, Ethno-Botany and Tapping Procedures of ...

    African Journals Online (AJOL)

    Potential, Distribution, Ethno-Botany and Tapping Procedures of Gum Producing Acacia Species in the Somali Region, Southeastern Ethiopia. ... Therefore, promotion of gum extraction in the Somali Region both for economic benefit of the community and sustainable management of the fragile ecosystem is recommended.

  15. Economic benefits flow from taps | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-08

    Dec 8, 2010 ... Villagers were unhappy about the time that women and children spent hauling ... Sun Qiu believes the end result is a better quality of life. ... tap water show the wisdom of communities managing their natural resources based ...

  16. Improving tapping mode atomic force microscopy with piezoelectric cantilevers

    International Nuclear Information System (INIS)

    Rogers, B.; Manning, L.; Sulchek, T.; Adams, J.D.

    2004-01-01

    This article summarizes improvements to the speed, simplicity and versatility of tapping mode atomic force microscopy (AFM). Improvements are enabled by a piezoelectric microcantilever with a sharp silicon tip and a thin, low-stress zinc oxide (ZnO) film to both actuate and sense deflection. First, we demonstrate self-sensing tapping mode without laser detection. Similar previous work has been limited by unoptimized probe tips, cantilever thicknesses, and stress in the piezoelectric films. Tests indicate self-sensing amplitude resolution is as good or better than optical detection, with double the sensitivity, using the same type of cantilever. Second, we demonstrate self-oscillating tapping mode AFM. The cantilever's integrated piezoelectric film serves as the frequency-determining component of an oscillator circuit. The circuit oscillates the cantilever near its resonant frequency by applying positive feedback to the film. We present images and force-distance curves using both self-sensing and self-oscillating techniques. Finally, high-speed tapping mode imaging in liquid, where electric components of the cantilever require insulation, is demonstrated. Three cantilever coating schemes are tested. The insulated microactuator is used to simultaneously vibrate and actuate the cantilever over topographical features. Preliminary images in water and saline are presented, including one taken at 75.5 μm/s - a threefold improvement in bandwidth versus conventional piezotube actuators

  17. Hydrogen isotopes identification with the electromagnetic calorimeter TAPS

    International Nuclear Information System (INIS)

    Matulewicz, T.; Aphecetche, L.; Charbonnier, Y.; Delagrange, H.; Martinez, G.; Schutz, Y.; Marques, F.M.; Diaz, J.; and others.

    1996-01-01

    A new method has been developed to identify protons and more generally charged massive particles, like charged pions, hydrogen isotopes and heavier particles reaching the TAPS detector. The method was tested on events from the reaction Ar+Ca at 180 A.MeV. (K.A.)

  18. Capillary forces in tapping mode atomic force microscopy

    NARCIS (Netherlands)

    Zitzler, L.; Herminghaus, S.; Mugele, Friedrich Gunther

    2002-01-01

    We investigated the influence of the relative humidity on amplitude and phase of the cantilever oscillation while operating an atomic force microscope (AFM) in the tapping mode. If the free oscillation amplitude A0 exceeds a certain critical amplitude Ac, the amplitude- and phase-distance curves

  19. Frankincense tapping reduces the carbohydrate storage of Boswellia trees

    NARCIS (Netherlands)

    Mengistu, T.; Sterck, F.J.; Fetene, M.; Bongers, F.

    2013-01-01

    Carbohydrates fixed by photosynthesis are stored in plant organs in the form of starch or sugars. Starch and sugars sum to the total non-structural carbohydrate pool (TNC) and may serve as intermediate pools between assimilation and utilization. We examined the impact of tapping on TNC

  20. Assessment of Working Scientifically--The TAPS Focused Assessment Approach

    Science.gov (United States)

    McMahon, Kendra

    2018-01-01

    The Teacher Assessment in Primary Science (TAPS) Focused Assessment approach embeds assessment within normal classroom science activities. Essentially, a Focused Assessment is a lesson plan for a science inquiry, with an identified focus for assessment and guidance on how to interpret the children's responses in relation to expectations for that…

  1. Media Leader Tapped to Head New York City Schools

    Science.gov (United States)

    Samuels, Christina A.

    2010-01-01

    When Mayor Michael R. Bloomberg sought a leader for the New York City schools in 2002, his outside-the-box choice was Joel I. Klein, a former assistant U.S. attorney general who had no experience as a school administrator. Eight years later, in seeking a replacement for Mr. Klein, Mr. Bloomberg has tapped yet another person from outside education:…

  2. Gulf digs in to tap a major uranium orebody

    International Nuclear Information System (INIS)

    Jackson, D.

    1977-01-01

    The progress and future plans of Gulf Mineral Resources Co. for tapping and developing a major uranium orebody via two concrete-lined shafts in the Grants uranium mineral belt in New Mexico are discussed. The mineralogy of the Grants belt is discussed as it relates to the Gulf development project. Numerous pictures of the operation are included

  3. CORE Organic II - Tapping into Europe's organic Trend

    OpenAIRE

    Anonymous,

    2012-01-01

    Organic food production has continued to grow in popularity, partly because it taps into a number ofcontemporary consumer concerns such as animal welfare and healthy eating. A new project aims tocapitalise on this demand by ensuring better research coordination across Europe.

  4. Multiplication of Legionella spp. in tap water containing Hartmannella vermiformis.

    Science.gov (United States)

    Wadowsky, R M; Wilson, T M; Kapp, N J; West, A J; Kuchta, J M; States, S J; Dowling, J N; Yee, R B

    1991-07-01

    A model was developed to study the multiplication of various Legionella spp. in tap water containing Hartmannella vermiformis. Tap water cultures prepared with the following components were suitable for the multiplication studies: Legionella spp., 10(3) CFU/ml; H. vermiformis, 10(4.4) cysts per ml; and killed Pseudomonas paucimobilis, 10(9) cells per ml. Cocultures were incubated at 37 degrees C for at least 1 week. The following legionellae multiplied in tap water cocultures in each replicate experiment: L. bozemanii (WIGA strain), L. dumoffii (NY-23 and TX-KL strains), L. micdadei (two environmental strains), and L. pneumophila (six environmental strains and one clinical isolate). Growth yield values for these strains were 0.6 to 3.5 log CFU/ml. Legionellae which did not multiply in replicate cocultures included L. anisa (one strain), L. bozemanii (MI-15 strain), L. micdadei (a clinical isolate), L. longbeachae, (one strain), and L. pneumophila (Philadelphia 1 strain). L. gormanii and an environmental isolate of L. pneumophila multiplied in only one of three experiments. None of the legionellae multiplied in tap water containing only killed P. paucimobilis. The mean growth yield (+/- standard deviation) of H. vermiformis in the cocultures was 1.2 +/- 0.1 log units/ml. H. vermiformis supports multiplication of only particular strains of legionellae, some of which are from diverse origins.

  5. Eliciting Cervical Vestibular-Evoked Myogenic Potentials by Bone-Conducted Vibration via Various Tapping Sites.

    Science.gov (United States)

    Tseng, Chia-Chen; Young, Yi-Ho

    2016-01-01

    This study compared bone-conducted vibration (BCV) cervical vestibular-evoked myogenic potentials (cVEMPs) via tapping at various skull sites in healthy subjects and patients with vestibular migraine (VM) to optimize stimulation conditions. Twenty healthy subjects underwent a series of cVEMP tests by BCV tapping via a minishaker at the Fz (forehead), Cz (vertex), and inion (occiput) sites in a randomized order of tapping sites. Another 20 VM patients were also enrolled in this study for comparison. All 20 healthy subjects had clear BCV cVEMPs when tapping at the inion (100%) or Cz (100%), but not at the Fz (75%). Mean p13 and n23 latencies from the Cz tapping were significantly longer than those from the Fz tapping, but not longer than those from the inion tapping. Unlike healthy subjects, tapping at the Cz (95%) elicited a significantly higher response rate of present cVEMPs than tapping at the inion (78%) in 20 VM patients (40 ears), because seven of nine VM ears with absent cVEMPs by inion tapping turned out to be present cVEMPs by Cz tapping. While both inion and Cz tapping elicited 100% response rate of cVEMPs for healthy individuals, Cz tapping had a higher response rate of cVEMPs than inion tapping for the VM group. In cases of total loss of saccular function, cVEMPs could not be activated by either inion or Cz tapping. However, if residual saccular function remains, Cz tapping may activate saccular afferents more efficiently than inion tapping.

  6. BIOMECHANICAL EVALUATION OF THE INFLUENCE OF CERVICAL SCREWS TAPPING AND DESIGN.

    Science.gov (United States)

    Silva, Patricia; Rosa, Rodrigo César; Shimano, Antonio Carlos; Albuquerque de Paula, Francisco José; Volpon, José Batista; Aparecido Defino, Helton Luiz

    2009-01-01

    To assess if the screw design (self-drilling/self-tapping) and the pilot hole tapping could affect the insertion torque and screw pullout strength of the screw used in anterior fixation of the cervical spine. Forty self-tapping screws and 20 self-drilling screws were inserted into 10 models of artificial bone and 10 cervical vertebrae of sheep. The studied parameters were the insertion torque and pullout strength. The following groups were created: Group I-self-tapping screw insertion after pilot hole drilling and tapping; Group II-self-tapping screw insertion after pilot hole drilling without tapping; Group III-self-drilling screw insertion without drilling and tapping. In Groups I and II, the pilot hole had 14.0 mm in depth and was made with a 3mmn drill, while tapping was made with a 4mm tap. The insertion torque was measured and the pullout test was performed. The comparison between groups was made considering the mean insertion torque and the maximum mean pullout strength with the variance analysis (ANOVA; p≤ 0.05). Previous drilling and tapping of pilot hole significantly decreased the insertion torque and the pullout strength. The insertion torque and pullout strength of self-drilling screws were significantly higher when compared to self-tapping screws inserted after pilot hole tapping.

  7. Effects of age, task, and frequency on variability of finger tapping.

    Science.gov (United States)

    Sommervoll, Yngve; Ettema, Gertjan; Vereijken, Beatrix

    2011-10-01

    The goal was to assess whether prior studies might have overestimated performance variability in older adults in dual task conditions by relying on primary motor tasks that are not constant with aging. 30 younger and 31 older adults performed a bimanual tapping task at four different frequencies in isolation or concurrently with a secondary task. Results showed that performance of younger and older adults was not significantly different in performing the tapping task at all frequencies and with either secondary task, as indicated by mean tapping performance and low number of errors in the secondary tasks. Both groups showed increased variability as tapping frequency increased and with the presence of a secondary task. Tapping concurrently while reading words increased tapping variability more than tapping concurrently while naming colours. Although older participants' performances were overall more variable, no interaction effects with age were found and at the highest frequencies of tapping, younger and older participants did not differ in performance.

  8. Brain activity during bilateral rapid alternate finger tapping measured with magnetoencephalography

    Science.gov (United States)

    Fukuda, Hiroshi; Odagaki, Masato; Hiwaki, Osamu; Kodabashi, Atsushi; Fujimoto, Toshiro

    2009-04-01

    Using magnetoencephalography (MEG), brain regions involved in an alternate bimanual tapping task by index fingers triggered with spontaneous timing were investigated. The tapping mode in which both index fingers moved simultaneously was interlaced during the task. The groups of the alternate tapping (AL mode) and the simultaneous tapping (SI mode) were extracted from the successive alternating taps with a histogram of intervals between the right and left index fingers. MEG signals in each mode were averaged separately before and after the tapping initiation of the dominant index finger. The activities of the contralateral sensorimotor cortex before and after the tapping initiation in the AL mode were larger than that in the SI mode. The result indicates that the activity of the contralateral sensorimotor cortex depends on the degree of achievement in the difficult motor task such as the voluntary alternate tapping movements.

  9. TAPS: an automated tool for identification of skills, knowledges, and abilities using natural language task description

    International Nuclear Information System (INIS)

    Jorgensen, C.C.; Carter, R.J.

    1986-01-01

    A prototype, computer-based tool (TAPS) has been developed to aid training system developers in identifying skills, knowledges, and abilities (SKAs) during task analysis. TAPS uses concepts of flexible pattern matching to evaluate English descriptions of job behaviors and to recode them as SKA lists. This paper addresses the rationale for TAPS and describes its design including SKA definitions and task analysis logic. It also presents examples of TAPS's application

  10. An estimation of finger-tapping rates and load capacities and the effects of various factors.

    Science.gov (United States)

    Ekşioğlu, Mahmut; İşeri, Ali

    2015-06-01

    The aim of this study was to estimate the finger-tapping rates and finger load capacities of eight fingers (excluding thumbs) for a healthy adult population and investigate the effects of various factors on tapping rate. Finger-tapping rate, the total number of finger taps per unit of time, can be used as a design parameter of various products and also as a psychomotor test for evaluating patients with neurologic problems. A 1-min tapping task was performed by 148 participants with maximum volitional tempo for each of eight fingers. For each of the tapping tasks, the participant with the corresponding finger tapped the associated key in the standard position on the home row of a conventional keyboard for touch typing. The index and middle fingers were the fastest fingers for both hands, and little fingers the slowest. All dominant-hand fingers, except little finger, had higher tapping rates than the fastest finger of the nondominant hand. Tapping rate decreased with age and smokers tapped faster than nonsmokers. Tapping duration and exercise had also significant effect on tapping rate. Normative data of tapping rates and load capacities of eight fingers were estimated for the adult population. In designs of psychomotor tests that require the use of tapping rate or finger load capacity data, the effects of finger, age, smoking, and tapping duration need to be taken into account. The findings can be used for ergonomic designs requiring finger-tapping capacity and also as a reference in psychomotor tests. © 2015, Human Factors and Ergonomics Society.

  11. TAPS: an automated tool for identification of skills, knowledges, and abilities using natural language task description

    Energy Technology Data Exchange (ETDEWEB)

    Jorgensen, C.C.; Carter, R.J.

    1986-01-01

    A prototype, computer-based tool (TAPS) has been developed to aid training system developers in identifying skills, knowledges, and abilities (SKAs) during task analysis. TAPS uses concepts of flexible pattern matching to evaluate English descriptions of job behaviors and to recode them as SKA lists. This paper addresses the rationale for TAPS and describes its design including SKA definitions and task analysis logic. It also presents examples of TAPS's application.

  12. TAPS - An automated tool for identification of skills, knowledges, and abilities using natural language task description

    International Nuclear Information System (INIS)

    Jorgensen, C.C.; Carter, R.J.

    1986-01-01

    A prototype, computer-based tool (TAPS) has been developed to aid training system developers in identifying skills, knowledges, and abilities (SKAs) during task analysis. TAPS uses concepts of flexible pattern matching to evaluate English descriptions of job behaviors and to recode them as SKA lists. This paper addresses the rationale for TAPS and describes its design including SKA definitions and task analysis logic. It also presents examples of TAPS's application

  13. Estimation method of finger tapping dynamics using simple magnetic detection system

    Science.gov (United States)

    Kandori, Akihiko; Sano, Yuko; Miyashita, Tsuyoshi; Okada, Yoshihisa; Irokawa, Masataka; Shima, Keisuke; Tsuji, Toshio; Yokoe, Masaru; Sakoda, Saburo

    2010-05-01

    We have developed the simple estimation method of a finger tapping dynamics model for investigating muscle resistance and stiffness during tapping movement in normal subjects. We measured finger tapping movements of 207 normal subjects using a magnetic finger tapping detection system. Each subject tapped two fingers in time with a metronome at 1, 2, 3, 4, and 5 Hz. The velocity and acceleration values for both the closing and opening tapping data were used to estimate a finger tapping dynamics model. Using the frequency response of the ratio of acceleration to velocity of the mechanical impedance parameters, we estimated the resistance (friction coefficient) and compliance (stiffness). We found two dynamics models for the maximum open position and tap position. In the maximum open position, the extensor muscle resistance was twice as high as the flexor muscle resistance and males had a higher spring constant. In the tap position, the flexor muscle resistance was much higher than the extensor muscle resistance. This indicates that the tapping dynamics in the maximum open position are controlled by the balance of extensor and flexor muscle friction resistances and the flexor stiffness, and the flexor friction resistance is the main component in the tap position. It can be concluded that our estimation method makes it possible to understand the tapping dynamics.

  14. Estimation method of finger tapping dynamics using simple magnetic detection system.

    Science.gov (United States)

    Kandori, Akihiko; Sano, Yuko; Miyashita, Tsuyoshi; Okada, Yoshihisa; Irokawa, Masataka; Shima, Keisuke; Tsuji, Toshio; Yokoe, Masaru; Sakoda, Saburo

    2010-05-01

    We have developed the simple estimation method of a finger tapping dynamics model for investigating muscle resistance and stiffness during tapping movement in normal subjects. We measured finger tapping movements of 207 normal subjects using a magnetic finger tapping detection system. Each subject tapped two fingers in time with a metronome at 1, 2, 3, 4, and 5 Hz. The velocity and acceleration values for both the closing and opening tapping data were used to estimate a finger tapping dynamics model. Using the frequency response of the ratio of acceleration to velocity of the mechanical impedance parameters, we estimated the resistance (friction coefficient) and compliance (stiffness). We found two dynamics models for the maximum open position and tap position. In the maximum open position, the extensor muscle resistance was twice as high as the flexor muscle resistance and males had a higher spring constant. In the tap position, the flexor muscle resistance was much higher than the extensor muscle resistance. This indicates that the tapping dynamics in the maximum open position are controlled by the balance of extensor and flexor muscle friction resistances and the flexor stiffness, and the flexor friction resistance is the main component in the tap position. It can be concluded that our estimation method makes it possible to understand the tapping dynamics.

  15. Effects of aging on control of timing and force of finger tapping.

    Science.gov (United States)

    Sasaki, Hirokazu; Masumoto, Junya; Inui, Nobuyuki

    2011-04-01

    The present study examined whether the elderly produced a hastened or delayed tap with a negative or positive constant intertap interval error more frequently in self-paced tapping than in the stimulus-synchronized tapping for the 2 N target force at 2 or 4 Hz frequency. The analysis showed that, at both frequencies, the percentage of the delayed tap was larger in the self-paced tapping than in the stimulus-synchronized tapping, whereas the hastened tap showed the opposite result. At the 4 Hz frequency, all age groups had more variable intertap intervals during the self-paced tapping than during the stimulus-synchronized tapping, and the variability of the intertap intervals increased with age. Thus, although the increase in the frequency of delayed taps and variable intertap intervals in the self-paced tapping perhaps resulted from a dysfunction of movement timing in the basal ganglia with age, the decline in timing accuracy was somewhat improved by an auditory cue. The force variability of tapping at 4 Hz further increased with age, indicating an effect of aging on the control of force.

  16. 40 CFR 141.86 - Monitoring requirements for lead and copper in tap water.

    Science.gov (United States)

    2010-07-01

    ... copper in tap water. 141.86 Section 141.86 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 141.86 Monitoring requirements for lead and copper in tap water. (a) Sample site location. (1) By the... the water system can collect the number of lead and copper tap samples required in paragraph (c) of...

  17. The Ability to Tap to a Beat Relates to Cognitive, Linguistic, and Perceptual Skills

    Science.gov (United States)

    Tierney, Adam T.; Kraus, Nina

    2013-01-01

    Reading-impaired children have difficulty tapping to a beat. Here we tested whether this relationship between reading ability and synchronized tapping holds in typically-developing adolescents. We also hypothesized that tapping relates to two other abilities. First, since auditory-motor synchronization requires monitoring of the relationship…

  18. Oropharyngeal Tularemia Outbreak Associated with Drinking Contaminated Tap Water, Turkey, July-September 2013.

    Science.gov (United States)

    Aktas, Dilber; Celebi, Bekir; Isik, Mehmet Emirhan; Tutus, Celal; Ozturk, Huseyin; Temel, Fehminaz; Kizilaslan, Mecit; Zhu, Bao-Ping

    2015-12-01

    In 2013, an oropharyngeal tularemia outbreak in Turkey affected 55 persons. Drinking tap water during the likely exposure period was significantly associated with illness (attack rate 27% vs. 11% among non-tap water drinkers). Findings showed the tap water source had been contaminated by surface water, and the chlorination device malfunctioned.

  19. TAp63 suppress metastasis via miR-133b in colon cancer cells.

    Science.gov (United States)

    Lin, C W; Li, X R; Zhang, Y; Hu, G; Guo, Y H; Zhou, J Y; Du, J; Lv, L; Gao, K; Zhang, Y; Deng, H

    2014-04-29

    TAp63 is a tumour-suppressor protein that is often underexpressed in various types of cancer. It has been shown to activate gene transcription depending on the transcription domain and to be closely related with metastasis. In this study, we demonstrate that TAp63 suppresses metastasis in colon cancer cells through microRNA-133b. We evaluated the correlation of TAp63 and miR-133b with HT-29 and SW-620 cells and investigated the roles of TAp63 in the expression of RhoA, E-cadherin and vimentin. We further investigated the roles of TAp63-mediated invasion and migration of colon cancer cells. TAp63 expression is downregulated in colon cancer, and microRNA-133b is a transcriptional target of TAp63. Furthermore, microRNA-133b is essential for the inhibitory effects of TAp63 on RhoA, E-cadherin and vimentin. Moreover, TAp63 inhibits cell migration and invasion through microRNA-133b. Correspondingly, the inhibitory effect of TAp63 on RhoA, E-cadherin, vimentin, migration and invasion can be blocked by the microRNA-133b inhibitor. TAp63 and microRNA-133b were able to suppress the metastasis of colon cancer. Both TAp63 and microRNA-133b may be potential biomarkers for diagnosis in colon cancer metastasis and may provide unique therapeutic targets for this common malignancy.

  20. Recent Results from the CBELSA/TAPS Experiment at ELSA

    Science.gov (United States)

    Thiel, A.

    To determine the excitation spectrum of the nucleon, measurements of different observables in meson photoproduction are necessary. Many of these observables can be measured with the CBELSA/TAPS experiment, located at the ELSA accelerator in Bonn. The calorimeter system is ideally suited to measure reactions containing photons, giving an opportunity to measure final states comprising neutral mesons like π0 or η. A linearly or circularly polarized photon beam was used in combination with a longitudinally or transversely polarized butanol target. This allows the measurement of different (double) polarization observables like P, T E, G, and H. This contribution reports on the measurement of polarization observables in single or double meson photoproduction off the proton, measured with the CBELSA/TAPS experiment.

  1. Quality of Pinus elliottii sawn timber from tapped forests

    Directory of Open Access Journals (Sweden)

    Pedro Henrique Gonzalez de Cademartori

    2012-12-01

    Full Text Available This study aimed to characterize the quality of Pinus elliottii sawn timber extracted from tapped forests and processed in a sawmill in São José do Norte (RS. Four butt logs and four upper logs for each of the three existing diameter grades were selected and sawed. The wood pieces were analyzed after sawing and after kiln drying. The presence of knots, which occurred due to the absence of forest management and influenced the qualitative classification of the wood pieces, was observed mainly in the samples from upper logs. The process of resin tapping contributed to a higher incidence of resin pockets in the samples from butt logs, also influencing the qualitative classification of the samples. The appearance of drying defects did not modify the classification of the wood samples from butt and upper logs.

  2. Radioactivity of tap water in the Republic of Croatia

    International Nuclear Information System (INIS)

    Cesar, D.; Maracic, M.; Franic, Z.; Kovac, J.

    1994-01-01

    The purpose of the paper was to establish the difference between radioactivity level measured in tap water in relation to maximum permissible concentrations determined by law in the Republic of Croatia. Tables 1 and 2 give percentages of total beta activity in tap water of several cities in Croatia and Table 3 of 137 Cs, 3 H and 90 Sr specific activities, in relation to permissible levels. On basis of these data it could be concluded that total beta activity has exponentially decreased over the past 30 years and radioactivity in tape water of Croatia has never exceeded permissible levels. Taking in account possible hazards to human health that might be caused by the presence of radioactivity in water, this kind of investigation should be continued also in the future

  3. A General Approach for Orthogonal 4-Tap Integer Multiwavelet Transforms

    Directory of Open Access Journals (Sweden)

    Mingli Jing

    2010-01-01

    Full Text Available An algorithm for orthogonal 4-tap integer multiwavelet transforms is proposed. We compute the singular value decomposition (SVD of block recursive matrices of transform matrix, and then transform matrix can be rewritten in a product of two block diagonal matrices and a permutation matrix. Furthermore, we factorize the block matrix of block diagonal matrices into triangular elementary reversible matrices (TERMs, which map integers to integers by rounding arithmetic. The cost of factorizing block matrix into TERMs does not increase with the increase of the dimension of transform matrix, and the proposed algorithm is in-place calculation and without allocating auxiliary memory. Examples of integer multiwavelet transform using DGHM and CL are given, which verify that the proposed algorithm is an executable algorithm and outperforms the existing algorithm for orthogonal 4-tap integer multiwavelet transform.

  4. Lithium in Tap Water and Suicide Mortality in Japan

    Directory of Open Access Journals (Sweden)

    Takeshi Terao

    2013-11-01

    Full Text Available Lithium has been used as a mood-stabilizing drug in people with mood disorders. Previous studies have shown that natural levels of lithium in drinking water may protect against suicide. This study evaluated the association between lithium levels in tap water and the suicide standardized mortality ratio (SMR in 40 municipalities of Aomori prefecture, which has the highest levels of suicide mortality rate in Japan. Lithium levels in the tap water supplies of each municipality were measured using inductively coupled plasma-mass spectrometry. After adjusting for confounders, a statistical trend toward significance was found for the relationship between lithium levels and the average SMR among females. These findings indicate that natural levels of lithium in drinking water might have a protective effect on the risk of suicide among females. Future research is warranted to confirm this association.

  5. Recent results from the CBELSA/TAPS experiment at ELSA

    International Nuclear Information System (INIS)

    Thiel, A.

    2016-01-01

    To determine the excitation spectrum of the nucleon, measurements of different observables in meson photoproduction are necessary. Many of these observables can be measured with the CBELSA/TAPS experiment, located at the ELSA accelerator in Bonn. The calorimeter system is ideally suited to measure reactions containing photons, giving an opportunity to measure final states comprising neutral mesons like π"0 or η. A linearly or circularly polarized photon beam was used in combination with a longitudinally or transversely polarized butanol target. This allows the measurement of different (double) polarization observables like P, T E, G, and H. This contribution reports on the measurement of polarization observables in single or double meson photoproduction off the proton, measured with the CBELSA/TAPS experiment. (author)

  6. Manual asymmetries in bimanual isochronous tapping tasks in children.

    Science.gov (United States)

    Faria, Inês; Diniz, Ana; Barreiros, João

    2017-01-01

    Tapping tasks have been investigated throughout the years, with variations in features such as the complexity of the task, the use of one or both hands, the employ of auditory or visual stimuli, and the characteristics of the subjects. The evaluation of lateral asymmetries in tapping tasks in children offers an insight into the structure of rhythmic movements and handedness at early stages of development. The current study aims to investigate the ability of children (aged six and seven years-old) to maintain a rhythm, in a bimanual tapping task at two different target frequencies, as well as the manual asymmetries displayed while doing so. The analyzed data in this work are the series of the time intervals between successive taps. We suggest several profiles of behavior, regarding the overall performance of children in both tempo conditions. We also propose a new method of quantifying the variability of the performance and the asymmetry of the hands, based on ellipses placed on scatter plots of the non-dominant-dominant series versus the dominant-non-dominant series. We then use running correlations to identify changes of coordination tendencies over time. The main results show that variability is larger in the task with the longer target interval. Furthermore, most children evidence lateral asymmetries, but in general they show the capacity to maintain the mean of consecutive intertap intervals of both hands close to the target interval. Finally, we try to interpret our findings in the light of existing models and timing modes. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Determination of the Tapping Part Diameter of the Thread Mill

    Directory of Open Access Journals (Sweden)

    A. E. Dreval'

    2015-01-01

    Full Text Available Currently, there is a tendency to increase the proportion of thread milling operations, among other ways of tapping, which is associated with increasing number of CNC machines, flexibility and versatility of the process.Developments presently existing in the RF and used in the thread mills deal, mainly, with the thread milling cutter designs, to process internal and external thread with straight flutes made from high-speed steel.The paper presents a technique to calculate and select the initial design parameters, i.e. the external diameter of the tapping part of thread milling cutter, which is chosen as a basic computational design. The analysis of directories of tool companies containing foreign de-signs of solid thread end-milling cutters has shown that most of them rep-resent the thread cutter designs made of solid carbide. There are solid and interlocking side milling cutters, which use a tapping part both as a single-disk and as a multi-disk one; chip flutes are made to be both as direct and as screw; solid designs of cutters are made from carbide with a diameter of up to 20 ... 25 mm; thread cutters can be left- and right-hand cutting; Designs of the combined thread mills are proposed; internal channels are used for coolant supply.It is shown that the purpose of the external diameter of the tapping part of the thread mill should take into account the effect of the thread mill diameter on the milling process performance, precision of thread profile received, taper thread, tool strength, and the volume of flutes.The analysis has shown that when choosing the external diameter of the thread mill it worth taking its maximum diameter to improve the char-acteristics of the process under the restrictions imposed on the accuracy of the formed thread.

  8. Mechanical characteristics of connection for GFRP plates using tapping screws

    Science.gov (United States)

    Inoue, Yuya; Duong, Nguyen Ngoc; Satake, Chito; Matsumoto, Yukihiro

    2017-10-01

    FRP material has good characteristics such as light-weight, high-strength and high-corrosion resistance. Light-weight structure possesses some advantages over the rational constructing procedure such as self-building structures. In recent years, mechanical characteristics of FRP joints using bolts and/or rivet are investigated in detail, and they are used in many FRP structures. However, the bolts lack bearing strength compared with material strength and the joint needs the prepared bolt hole. In this paper, an alternative joint system for FRP structures using tapping screw is proposed and mechanical characteristics are investigated through experiment. Tapping screw has some advantages; easy-to-use, light-weight and high bearing strength. Then, the results of double-lapped tensile shear tests having one, four and eight tapping screws along longitudinal direction are shown. Moreover, it is shown that longitudinal stress distribution is approximately corresponding to the theoretical stress distribution of double-lapped adhesively bonded joints. Based on these, it is proposed that joint strength can be estimated by using the present calculation method.

  9. Stroking and tapping the skin: behavioral and electrodermal effects.

    Science.gov (United States)

    Etzi, Roberta; Carta, Carlotta; Gallace, Alberto

    2018-02-01

    Being caressed represents one of the most typical expressions of affection conveyed by touch. Converging evidence suggests that the pleasant perception of gentle and slow stroking delivered to the hairy skin is mediated by C-Tactile afferents (CTs). While behavioral and neural responses to CT-optimal touch have been moderately explored so far, less is known about the autonomic reaction to different kinds of touch (both CT-optimal and not). Here, we investigated whether physiological arousal varies as a function of the specific tactile stimulation provided. Stroking (slow: 3 cm/s 'CT-optimal'; or fast: 30 cm/s) and tapping (random or fixed spatial order) stimulations were delivered to the participants' forearm with a brush, for durations of 9 or 60 s. Participants' skin conductance response (SCR) and level (SCL), as well as subjective evaluations, were recorded. The results revealed that being stroked (at both the velocities) induced higher SCR and SCL than being tapped. Moreover, while higher SCR was elicited by CT-suboptimal stroking compared to CT-optimal stroking, SCL was not affected differently by CT-optimal touch. No differences were found between the effects of 9 and 60 s stimulations. Slow stroking was evaluated as the most pleasant, relaxing and 'social' type of touch compared to the other tactile stimulations. Taken together, these findings shed light on the psychophysiological responses to stroking (including CT-optimal touch) and tapping, and contribute to elucidate the mechanisms underlying hedonic tactile perception.

  10. Rhythmic finger tapping reveals cerebellar dysfunction in essential tremor.

    Science.gov (United States)

    Buijink, A W G; Broersma, M; van der Stouwe, A M M; van Wingen, G A; Groot, P F C; Speelman, J D; Maurits, N M; van Rootselaar, A F

    2015-04-01

    Cerebellar circuits are hypothesized to play a central role in the pathogenesis of essential tremor. Rhythmic finger tapping is known to strongly engage the cerebellar motor circuitry. We characterize cerebellar and, more specifically, dentate nucleus function, and neural correlates of cerebellar output in essential tremor during rhythmic finger tapping employing functional MRI. Thirty-one propranolol-sensitive essential tremor patients with upper limb tremor and 29 healthy controls were measured. T2*-weighted EPI sequences were acquired. The task consisted of alternating rest and finger tapping blocks. A whole-brain and region-of-interest analysis was performed, the latter focusing on the cerebellar cortex, dentate nucleus and inferior olive nucleus. Activations were also related to tremor severity. In patients, dentate activation correlated positively with tremor severity as measured by the tremor rating scale part A. Patients had reduced activation in widespread cerebellar cortical regions, and additionally in the inferior olive nucleus, and parietal and frontal cortex, compared to controls. The increase in dentate activation with tremor severity supports involvement of the dentate nucleus in essential tremor. Cortical and cerebellar changes during a motor timing task in essential tremor might point to widespread changes in cerebellar output in essential tremor. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Macro and microelements in bottled and tap waters of Serbia

    Directory of Open Access Journals (Sweden)

    Petrović Tanja M.

    2012-01-01

    Full Text Available Comparative analysis between bottled and tap waters as well as its comparison with current Serbian regulations, European Union Directives and World Health Organization standard are shown in this paper. Thirteen bottled waters and fourteen tap waters from the territory of Serbia were analyzed in the Federal Institute for Geosciences and Natural Resources (BGR laboratory in Berlin, for the purpose of the “Geochemistry of European Bottled Water“ project conducted by EuroGeo Survey Geochemistry (EGS. Macrocomponents (main cations and anions of ground waters usually reflect on lithogeochemistry of the aquifer, while microcomponents indicate the circulation of ground water through the different lithological environment. Analyzed bottled waters could be classified as those with low mineral content (M<500 mg/L if HCO3 anion and Ca and Mg cations were the prevailing ones, or mineral (M>500 mg/L with prevailing HCO3 anion and Na cation. Waters with low mineral content were mainly from limestone and dolomite, while mineral waters mainly originated from magmatic and metamorphic rocks. Higher content of Cs, Li, Ge, Rb and F in bottled waters indicates the importance of the magmatic intrusions influence on their chemical composition. In some waters higher content of B, I, NH4, as well as of Tl and W has been observed which can be attributed to water’s circulation through different lithological complexes. Tap water was mostly obtained from groundwater (from Neogen and alluvial aquifers and karst springs with rest being those of rivers and surface accumulations. Tap waters from Central Serbia were with low mineral content, with prevailing HCO3 anion and Ca and Mg cations, while waters from Vojvodina, the northern province of Serbia, were with higher mineralization, HCO3-Na. Chemical analyses of the sampled tap waters showed good quality, with exception of waters from the cities of Senta and Zrenjanin in Vojvodina. High values of B (1170 and 895 g/L, As

  12. Spontaneous bimanual independence during parallel tapping and sawing

    Science.gov (United States)

    Baber, Chris

    2017-01-01

    The performance of complex polyrhythms—rhythms where the left and right hand move at different rates—is usually the province of highly trained individuals. However, studies in which hand movement is guided haptically show that even novices can perform polyrhythms with no or only brief training. In this study, we investigated whether novices are able to tap with one hand by matching different rates of a metronome while sawing with the other hand. This experiment was based on the assumption that saw movement is controlled consistently at a predictable rate without the need for paying primary attention to it. It would follow that consciously matching different stipulated metronome rates with the other hand would result in the spontaneous performance of polyrhythms. Six experimental conditions were randomised: single handed tapping and sawing as well as four bimanual conditions with expected ratios of 1:1 (performed with and without matching a metronome) as well as 3:4 and 4:3 (performed matching a metronome). Results showed that participants executed the saw movement at a consistent cycle duration of 0.44 [0.20] s to 0.51 [0.19] s across single and bimanual conditions, with no significant effect of the condition on the cycle duration (p = 0.315). Similarly, free tapping was executed at a cycle duration of 0.48 [0.22] s. In the bimanual conditions, we found that for a ratio of 4:3 (4 taps against 3 sawing cycles per measure), the observed and predicted ratio of 0.75 were not significantly different (p = 0.369), supporting our hypothesis of the spontaneous adoption of polyrhythms. However, for a ratio of 3:4 (3 taps against 4 sawing cycles per measure), the observed and predicted ratio differed (p = 0.016), with a trend towards synchronisation. Our findings show that bimanual independence when performing complex polyrhythms can in principle be achieved if the movement of one hand can be performed without paying much—if any—attention to it. In this paradigm

  13. Quantitative assessment of finger tapping characteristics in mild cognitive impairment, Alzheimer's disease, and Parkinson's disease.

    Science.gov (United States)

    Roalf, David R; Rupert, Petra; Mechanic-Hamilton, Dawn; Brennan, Laura; Duda, John E; Weintraub, Daniel; Trojanowski, John Q; Wolk, David; Moberg, Paul J

    2018-06-01

    Fine motor impairments are common in neurodegenerative disorders, yet standardized, quantitative measurements of motor abilities are uncommonly used in neurological practice. Thus, understanding and comparing fine motor abilities across disorders have been limited. The current study compared differences in finger tapping, inter-tap interval, and variability in Alzheimer's disease (AD), Parkinson's disease (PD), mild cognitive impairment (MCI), and healthy older adults (HOA). Finger tapping was measured using a highly sensitive light-diode finger tapper. Total number of finger taps, inter-tap interval, and intra-individual variability (IIV) of finger tapping was measured and compared in AD (n = 131), PD (n = 63), MCI (n = 46), and HOA (n = 62), controlling for age and sex. All patient groups had fine motor impairments relative to HOA. AD and MCI groups produced fewer taps with longer inter-tap interval and higher IIV compared to HOA. The PD group, however, produced more taps with shorter inter-tap interval and higher IIV compared to HOA. Disease-specific changes in fine motor function occur in the most common neurodegenerative diseases. The findings suggest that alterations in finger tapping patterns are common in AD, MCI, and PD. In addition, the present results underscore the importance of motor dysfunction even in neurodegenerative disorders without primary motor symptoms.

  14. Synergistic cooperation of MDM2 and E2F1 contributes to TAp73 transcriptional activity

    International Nuclear Information System (INIS)

    Kasim, Vivi; Huang, Can; Zhang, Jing; Jia, Huizhen; Wang, Yunxia; Yang, Li; Miyagishi, Makoto; Wu, Shourong

    2014-01-01

    Highlights: • MDM2 is a novel positive regulator of TAp73 transcriptional activity. • MDM2 colocalizes together and physically interacts with E2F1. • Synergistic cooperation of MDM2 and E2F1 is crucial for TAp73 transcription. • MDM2 regulates TAp73 transcriptional activity in a p53-independent manner. - Abstract: TAp73, a structural homologue of p53, plays an important role in tumorigenesis. E2F1 had been reported as a transcriptional regulator of TAp73, however, the detailed mechanism remains to be elucidated. Here we reported that MDM2-silencing reduced the activities of the TAp73 promoters and the endogenous TAp73 expression level significantly; while MDM2 overexpression upregulated them. We further revealed that the regulation of TAp73 transcriptional activity occurs as a synergistic effect of MDM2 and E2F1, most probably through their physical interaction in the nuclei. Furthermore, we also suggested that MDM2 might be involved in DNA damage-induced TAp73 transcriptional activity. Finally, we elucidated that MDM2-silencing reduced the proliferation rate of colon carcinoma cells regardless of the p53 status. Our data show a synergistic effect of MDM2 and E2F1 on TAp73 transcriptional activity, suggesting a novel regulation pathway of TAp73

  15. Synergistic cooperation of MDM2 and E2F1 contributes to TAp73 transcriptional activity

    Energy Technology Data Exchange (ETDEWEB)

    Kasim, Vivi, E-mail: vivikasim78@gmail.com [The Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Huang, Can; Zhang, Jing; Jia, Huizhen; Wang, Yunxia [The Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Yang, Li [The Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); The 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing 400044 (China); Miyagishi, Makoto [Molecular Composite Medicine Research Group, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba 305-8566 (Japan); Wu, Shourong, E-mail: shourongwu@hotmail.com [The Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044 (China); The 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing 400044 (China)

    2014-07-04

    Highlights: • MDM2 is a novel positive regulator of TAp73 transcriptional activity. • MDM2 colocalizes together and physically interacts with E2F1. • Synergistic cooperation of MDM2 and E2F1 is crucial for TAp73 transcription. • MDM2 regulates TAp73 transcriptional activity in a p53-independent manner. - Abstract: TAp73, a structural homologue of p53, plays an important role in tumorigenesis. E2F1 had been reported as a transcriptional regulator of TAp73, however, the detailed mechanism remains to be elucidated. Here we reported that MDM2-silencing reduced the activities of the TAp73 promoters and the endogenous TAp73 expression level significantly; while MDM2 overexpression upregulated them. We further revealed that the regulation of TAp73 transcriptional activity occurs as a synergistic effect of MDM2 and E2F1, most probably through their physical interaction in the nuclei. Furthermore, we also suggested that MDM2 might be involved in DNA damage-induced TAp73 transcriptional activity. Finally, we elucidated that MDM2-silencing reduced the proliferation rate of colon carcinoma cells regardless of the p53 status. Our data show a synergistic effect of MDM2 and E2F1 on TAp73 transcriptional activity, suggesting a novel regulation pathway of TAp73.

  16. Computationally efficient implementation of sarse-tap FIR adaptive filters with tap-position control on intel IA-32 processors

    OpenAIRE

    Hirano, Akihiro; Nakayama, Kenji

    2008-01-01

    This paper presents an computationally ef cient implementation of sparse-tap FIR adaptive lters with tapposition control on Intel IA-32 processors with single-instruction multiple-data (SIMD) capability. In order to overcome randomorder memory access which prevents a ectorization, a blockbased processing and a re-ordering buffer are introduced. A dynamic register allocation and the use of memory-to-register operations help the maximization of the loop-unrolling level. Up to 66percent speedup ...

  17. Computerized measures of finger tapping: effects of hand dominance, age, and sex.

    Science.gov (United States)

    Hubel, Kerry A; Reed, Bruce; Yund, E William; Herron, Timothy J; Woods, David L

    2013-06-01

    Computerized measures of digit tapping rate were obtained over 3 successive, 10-sec. periods in the right and left index fingers, from a community sample of 1,519 participants (ages 18 to 65 years; 607 men, 912 women). Differences between the dominant and non-dominant hands were found for tapping rate, movement initiation, and button down times, and the decline in tapping rate over the successive, 10-sec. periods. Declines were found in tapping rate in older participants in association with increased intertap variability. Men had higher tapping rates than women in all age ranges. The computerized finger tapping test is an efficient and precise measure of tapping speed and kinetics of potential utility in research and clinical studies of motor performance.

  18. PeakForce Tapping resolves individual microvilli on living cells.

    Science.gov (United States)

    Schillers, Hermann; Medalsy, Izhar; Hu, Shuiqing; Slade, Andrea L; Shaw, James E

    2016-02-01

    Microvilli are a common structure found on epithelial cells that increase the apical surface thus enhancing the transmembrane transport capacity and also serve as one of the cell's mechanosensors. These structures are composed of microfilaments and cytoplasm, covered by plasma membrane. Epithelial cell function is usually coupled to the density of microvilli and its individual size illustrated by diseases, in which microvilli degradation causes malabsorption and diarrhea. Atomic force microscopy (AFM) has been widely used to study the topography and morphology of living cells. Visualizing soft and flexible structures such as microvilli on the apical surface of a live cell has been very challenging because the native microvilli structures are displaced and deformed by the interaction with the probe. PeakForce Tapping® is an AFM imaging mode, which allows reducing tip-sample interactions in time (microseconds) and controlling force in the low pico-Newton range. Data acquisition of this mode was optimized by using a newly developed PeakForce QNM-Live Cell probe, having a short cantilever with a 17-µm-long tip that minimizes hydrodynamic effects between the cantilever and the sample surface. In this paper, we have demonstrated for the first time the visualization of the microvilli on living kidney cells with AFM using PeakForce Tapping. The structures observed display a force dependence representing either the whole microvilli or just the tips of the microvilli layer. Together, PeakForce Tapping allows force control in the low pico-Newton range and enables the visualization of very soft and flexible structures on living cells under physiological conditions. © 2015 The Authors Journal of Molecular Recognition Published by John Wiley & Sons Ltd.

  19. What is the risk of infecting a cerebrospinal fluid-diverting shunt with percutaneous tapping?

    Science.gov (United States)

    Spiegelman, Lindsey; Asija, Richa; Da Silva, Stephanie L; Krieger, Mark D; McComb, J Gordon

    2014-10-01

    Most CSF-diverting shunt systems have an access port that can be percutaneously tapped. Tapping the shunt can yield valuable information as to its function and whether an infection is present. The fear of causing a shunt infection by tapping may limit the physician's willingness to do so. The authors of this study investigate the risk of infecting a shunt secondary to percutaneous tapping. Following institutional review board approval, CSF specimens obtained from tapping an indwelling CSF-diverting shunt during the 2011 and 2012 calendar years were identified and matched with clinical information. A culture-positive CSF sample was defined as an infection. If results were equivocal, such as a broth-only-positive culture, a repeat CSF specimen was examined. The CSF was obtained by tapping the shunt access port with a 25-gauge butterfly needle after prepping the unshaven skin with chlorhexidine. During the study period, 266 children underwent 542 shunt taps. With 541 taps, no clinical evidence of a subsequent shunt infection was found. One child's CSF went from sterile to infected 11 days later; however, this patient had redness along the shunt tract at the time of the initial sterile tap. The risk of infection from tapping a shunt is remote if the procedure is done correctly.

  20. Vertical Finger Displacement Is Reduced in Index Finger Tapping During Repeated Bout Rate Enhancement.

    Science.gov (United States)

    Mora-Jensen, Mark Holten; Madeleine, Pascal; Hansen, Ernst Albin

    2017-10-01

    The present study analyzed (a) whether a recently reported phenomenon of repeated bout rate enhancement in finger tapping (i.e., a cumulating increase in freely chosen finger tapping frequency following submaximal muscle activation in the form of externally unloaded voluntary tapping) could be replicated and (b) the hypotheses that the faster tapping was accompanied by changed vertical displacement of the fingertip and changed peak force during tapping. Right-handed, healthy, and recreationally active individuals (n = 24) performed two 3-min index finger tapping bouts at freely chosen tapping frequency, separated by 10-min rest. The recently reported phenomenon of repeated bout rate enhancement was replicated. The faster tapping (8.8 ± 18.7 taps/min, corresponding to 6.0 ± 11.0%, p = .033) was accompanied by reduced vertical displacement (1.6 ± 2.9 mm, corresponding to 6.3 ± 14.9%, p = .012) of the fingertip. Concurrently, peak force was unchanged. The present study points at separate control mechanisms governing kinematics and kinetics during finger tapping.

  1. Association of TAP Gene Polymorphisms and Risk of Cervical Intraepithelial Neoplasia

    Directory of Open Access Journals (Sweden)

    Camilla Natter

    2013-01-01

    Full Text Available Background. Transporter associated with antigen processing (TAP is responsible for peptide loading onto class I major histocompatibility complex (MHC-I molecules. TAP seems to facilitate the detection of HPV by MHC-I molecules and contributes to successful eradication of HPV. TAP polymorphisms could have an important impact on the course of HPV infection. Objective. The aim of this study is to evaluate the association between five TAP gene polymorphisms and the risk of CIN. Methods. This case-control study investigated five common TAP polymorphisms in TAP1 (1341 and 2254 and TAP2 (1135, 1693, and 1993 in 616 women with CIN and 206 controls. Associations between gene polymorphisms and risk of CIN were analysed by univariate and multivariable models. The combined effect of the five TAP gene polymorphisms on the risk for CIN was investigated by haplotype analysis. Results. No significant difference in genotype distribution of the five TAP polymorphisms was observed in women with CIN and controls. Haplotype analysis revealed that women with haplotype mut-wt-wt-wt-wt (TAP polymorphisms t1135-t1341-t1693-t1993-t2254 had a significantly lower risk for CIN, compared to women with the haplotype wt-wt-wt-wt-wt (; OR 0.5 []. Conclusion. Identification of this haplotype combination could be used to identify women, less susceptible for development of CIN following HPV infection.

  2. Bimanual tapping of a syncopated rhythm reveals hemispheric preferences for relative movement frequencies.

    Science.gov (United States)

    Pflug, Anja; Gompf, Florian; Kell, Christian Alexander

    2017-08-01

    In bimanual multifrequency tapping, right-handers commonly use the right hand to tap the relatively higher rate and the left hand to tap the relatively lower rate. This could be due to hemispheric specializations for the processing of relative frequencies. An extension of the double-filtering-by-frequency theory to motor control proposes a left hemispheric specialization for the control of relatively high and a right hemispheric specialization for the control of relatively low tapping rates. We investigated timing variability and rhythmic accentuation in right handers tapping mono- and multifrequent bimanual rhythms to test the predictions of the double-filtering-by-frequency theory. Yet, hemispheric specializations for the processing of relative tapping rates could be masked by a left hemispheric dominance for the control of known sequences. Tapping was thus either performed in an overlearned quadruple meter (tap of the slow rhythm on the first auditory beat) or in a syncopated quadruple meter (tap of the slow rhythm on the fourth auditory beat). Independent of syncopation, the right hand outperformed the left hand in timing accuracy for fast tapping. A left hand timing benefit for slow tapping rates as predicted by the double-filtering-by-frequency theory was only found in the syncopated tapping group. This suggests a right hemisphere preference for the control of slow tapping rates when rhythms are not overlearned. Error rates indicate that overlearned rhythms represent hierarchically structured meters that are controlled by a single timer that could potentially reside in the left hemisphere. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Genetic Variants in TAP Are Associated with High-Grade Cervical Neoplasia

    Science.gov (United States)

    Einstein, Mark H.; Leanza, Suzanne; Chiu, Lydia G.; Schlecht, Nicolas F.; Goldberg, Gary L.; Steinberg, Bettie M.; Burk, Robert D.

    2018-01-01

    Purpose The transporter associated with antigen processing (TAP) is essential in assembling MHC-I proteins. Human papillomavirus (HPV) evades immune recognition by decreasing class I MHC cell surface expression through down-regulation of TAP1 levels. Consistent with heterogeneity in MHC expression is the individual variability in clearing detectable HPV infections. Genetic polymorphisms in TAP genes may affect protein structure, function, and the ability to clear HPV infection. Experimental Design Case-control study of women with cervical intraepithelial neoplasia (CIN) II or III (n = 114) and women without high-grade CIN (n = 366). Five nonsynonymous single nucleotide polymorphisms (SNP) in TAP1 and TAP2 were genotyped using DNA collected in cervicovaginal lavage samples using microsphere array technology (Luminex ×MAP). HPV typing was done using a PCR-based system with MY09/MY11 primers. TAP1 and TAP2 SNPs were validated by direct sequencing. Results Differences in allele distribution between women with high-grade cervical neoplasia and women without was seen for TAP1 I333V (P = 0.02) and TAP1 D637G (p = 0.01).The odds ratios (OR) for CIN III were significantly lower among carriers of the TAP1 I333V polymorphism (OR, 0.28; 95% confidence interval, 0.1-0.8), and TAP1 D637G polymorphism (OR, 0.27; 95% confidence interval, 0.1-0.7). These associations remained significant even after restricting the evaluation to women who were positive for high-risk HPV types. Conclusions In addition to the down-regulation of MHC-1 by oncogenic HPV, HPV pathogenesis might be facilitated by polymorphisms in the TAP proteins. Identifying TAP polymorphisms may potentially be used to identify women less susceptible to progression to high-grade CIN and cervical cancer. PMID:19188174

  4. Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization

    Science.gov (United States)

    Leonhardt, Ralf M.; Abrahimi, Parwiz; Mitchell, Susan M.; Cresswell, Peter

    2014-01-01

    The transporter associated with antigen processing (TAP) translocates peptide antigens into the lumen of the endoplasmic reticulum (ER) for loading onto major histocompatibility complex (MHC) class I molecules. MHC class I acquires its peptide cargo in the peptide loading complex (PLC), an oligomeric complex that the chaperone tapasin organizes by bridging TAP to MHC class I and recruiting accessory molecules such as ERp57 and calreticulin. Three tapasin binding sites on TAP have been described, two of which are located in the N-terminal domains (N domains) of TAP1 and TAP2. The third binding site is present in the core transmembrane domain (coreTMD) of TAP1 and is only used by the unassembled subunits. Tapasin is required to promote TAP stability, but through which binding site(s) it is acting is unknown. In particular the role of tapasin binding to the coreTMD of TAP1 single chains is mysterious as this interaction is lost upon TAP2 association. In this study, we map the respective binding site in TAP1 to the polar face of the amphipathic transmembrane helix TM9 and identify key residues that are essential to establish the interaction. We find that this interaction is dispensable for the peptide transport function but essential to achieve full stability of human TAP1. The interaction is also required for proper heterodimerization of the transporter. Based on similar results obtained using TAP mutants lacking tapasin binding to either N domain, we conclude that all three tapasin-binding sites in TAP cooperate to achieve high transporter stability and efficient heterodimerization. PMID:24501197

  5. Plano de social media marketing para a TAP Portugal

    OpenAIRE

    Lopes, Andreia Cristina Figueiredo

    2014-01-01

    Mestrado em Marketing O social media marketing adquire cada vez maior relevo para as empresas e exige, tal como noutras áreas de marketing, a delineação de um plano estratégico por forma a potenciar o seu sucesso. Tomando como objecto de estudo a companhia aérea TAP Portugal, foi elaborado um Plano de Social Media Marketing, com base no modelo conceptual de Barker et al. (2013), designado de "Social Media Planning Cycle". Para a elaboração do Plano, foram recolhidos dados primários, seguin...

  6. Tapping the zero-point energy as an energy source

    International Nuclear Information System (INIS)

    King, M.B.

    1991-01-01

    This paper reports that the hypothesis for tapping the zero-point energy (ZPE) arises by combining the theories of the ZPE with the theories of system self-organization. The vacuum polarization of atomic nuclei might allow their synchronous motion to activate a ZPE coherence. Experimentally observed plasma ion-acoustic anomalies as well as inventions utilizing cycloid ion motions may offer supporting evidence. The suggested experiment of rapidly circulating a charged plasma in a vortex ring might induce a sufficient zero-point energy interaction to manifest a gravitational anomaly. An invention utilizing abrupt E field rotation to create virtual charge exhibits excessive energy output

  7. Structural assessment of TAPS core shroud under accident loads

    International Nuclear Information System (INIS)

    Bhasin, Vivek; Kushwaha, H.S.; Mahajan, S.C.; Kakodkar, A.

    1996-09-01

    Over the last few years, the Core Shroud of Boiling Water Reactors (BWRs) operating in foreign countries, have developed cracks at weld locations. As a first step for assessment of structural safety of Tarapur Atomic Power Station (TAPS) core shroud, its detailed stress analysis was done for postulated accident loads. This report is concerned with structural assessment of core shroud, of BWR at TAPS, subjected to loads resulting from main steam line break (MSLB), recirculation line break (RLB) and safe shut down earthquake. The stress analysis was done for core shroud in healthy condition and without any crack since, visual examination conducted till now, do not indicate presence of any flaw. Dynamic structural analysis for MSLB and RLB events was done using dynamic load factor (DLF) method. The complete core shroud and its associated components were modelled and analysed using 3D plate/shell elements. Since, the components of core shroud are submerged in water, hence, hydrodynamic added mass was also considered for evaluation of natural frequencies. It was concluded that from structural point of view, adequate safety margin is available under all the accident loads. Nonlinear analysis was done to evaluate buckling/collapse load. The collapse/buckling load have sufficient margin against the allowable limits. The displacements are low hence, the insertion of control rod may not be affected. (author)

  8. Tapping and listening: a new approach to bolt looseness monitoring

    Science.gov (United States)

    Kong, Qingzhao; Zhu, Junxiao; Ho, Siu Chun Michael; Song, Gangbing

    2018-07-01

    Bolted joints are among the most common building blocks used across different types of structures, and are often the key components that sew all other structural parts together. Monitoring and assessment of looseness in bolted structures is one of the most attractive topics in mechanical, aerospace, and civil engineering. This paper presents a new percussion-based non-destructive approach to determine the health condition of bolted joints with the help of machine learning. The proposed method is very similar to the percussive diagnostic techniques used in clinical examinations to diagnose the health of patients. Due to the different interfacial properties among the bolts, nuts and the host structure, bolted joints can generate unique sounds when it is excited by impacts, such as from tapping. Power spectrum density, as a signal feature, was used to recognize and classify recorded tapping data. A machine learning model using the decision tree method was employed to identify the bolt looseness level. Experiments demonstrated that the newly proposed method for bolt looseness detection is very easy to implement by ‘listening to tapping’ and the monitoring accuracy is very high. With the rapid in robotics, the proposed approach has great potential to be implemented with intimately weaving robotics and machine learning to produce a cyber-physical system that can automatically inspect and determine the health of a structure.

  9. Experimental studies on intake headloss of a blasted lake tap

    International Nuclear Information System (INIS)

    Yang, James; Billstein, Mats; Engström, Fredrik; Strand, Rikard

    2014-01-01

    In existing reservoirs, construction of an intake is sometimes achieved by so-called lake tapping, a submerged tunnel piercing by blasting out the rock plug at the intake. The blasting process involves phases of rock, water, air and gas released from the explosive charge; the resulting entrance profile often differs from design assumptions. The intake headloss is a factor of concern for power generation. For a vertical intake formed by lake tapping, experiments have been carried out in a 1:30 physical model to examine the effect of entrance shapes on intake headlosses. The purpose is that, if there is potential to reduce the headlosses, the originally blasted intake shape would be modified. In the model, five alternative shapes are evaluated. The test results show that to enlarge the vertical shaft area is the most effective way to reduce the intake headloss; to further blast out a narrow channel upstream does not give much effect. Bearing in mind the risk of free-surface vortex at the intake, the influence of the intake modifications on vortex is also checked

  10. A prototype tap test imaging system: Initial field test results

    Science.gov (United States)

    Peters, J. J.; Barnard, D. J.; Hudelson, N. A.; Simpson, T. S.; Hsu, D. K.

    2000-05-01

    This paper describes a simple, field-worthy tap test imaging system that gives quantitative information about the size, shape, and severity of defects and damages. The system consists of an accelerometer, electronic circuits for conditioning the signal and measuring the impact duration, a laptop PC and data acquisition and processing software. The images are generated manually by tapping on a grid printed on a plastic sheet laid over the part's surface. A mechanized scanner is currently under development. The prototype has produced images for a variety of aircraft composite and metal honeycomb structures containing flaws, damages, and repairs. Images of the local contact stiffness, deduced from the impact duration using a spring model, revealed quantitatively the stiffness reduction due to flaws and damages, as well as the stiffness enhancement due to substructures. The system has been field tested on commercial and military aircraft as well as rotor blades and engine decks on helicopters. Field test results will be shown and the operation of the system will be demonstrated.—This material is based upon work supported by the Federal Aviation Administration under Contract #DTFA03-98-D-00008, Delivery Order No. IA016 and performed at Iowa State University's Center for NDE as part of the Center for Aviation Systems Reliability program.

  11. Guidelines for Effective TAP (Translation for Academic Purposes Tutorial Courses

    Directory of Open Access Journals (Sweden)

    Elham Yazdanmehr

    2014-03-01

    Full Text Available An increasing need is felt by the university students, especially at Master’s or PhD level, to get a satisfactory command of English so as to manage great amounts of technical materials and articles published internationally. Public and private language institutions, however, have not responded to this need properly specially in non-English speaking countries including Iran. Therefore, the only way left for the students is to demand tutorial sessions which are rare, and if existing, of diverse questionable quality. There seems to be a dearth of base-line or criteria released in any form to define and guide the tutors’ approach and techniques which can be in accordance with university students’ needs and purposes. Aiming to fill this gap, the present paper attempts to be a pioneering research in the realm of TAP (Translation for Academic Purposes tutorial courses and intends to provide guidelines on text selection, role allocation, timing, rate, assignments and other relevant issues in this area. The guidelines are provided based on a post facto case study carried out by one of the authors which created the motive for this research and may further clarify the significance of the issues discussed. The recommended guidelines consist of 5 basic elements and 3 principles. It was discovered, and is expected for others as well, that following these guidelines helps to manage a TAP course in the best and most fruitful way with the least time wasted and with satisfactory result.

  12. Tap-length optimization of adaptive filters used in stereophonic acoustic echo cancellation

    DEFF Research Database (Denmark)

    Kar, Asutosh; Swamy, M.N.S.

    2017-01-01

    An adaptive filter with a large number of weights or taps is necessary for stereophonic acoustic echo cancellation (SAEC), depending on the room impulse response and acoustic path where the cancellation is performed. However, a large tap-length results in slow convergence and increases...... the complexity of the tapped delay line structure for FIR adaptive filters. To overcome this problem, there is a need for an optimum tap-length-estimation algorithm that provides better convergence for the adaptive filters used in SAEC. This paper presents a solution to the problem of balancing convergence...... and steady-state performance of long length adaptive filters used for SAEC by proposing a new tap-length-optimization algorithm. The optimum tap length and step size of the adaptive filter are derived considering an impulse response with an exponentially-decaying envelope, which models a wide range...

  13. Zinc sacrificial anode behavior at elevated temperatures in sodium chloride and tap water environments

    International Nuclear Information System (INIS)

    Othman, Othman Mohsen

    2005-01-01

    Zinc sacrificial anode coupled to mild steel was tested in sodium chloride and tap water environments at elevated temperatures. The anode failed to protect the mild steel specimens in tap water environment at all temperatures specified for this study. This was partly due to the high resistivity of the medium. The temperature factor did not help to activate the anode in water tap medium. In sodium chloride environment the anode demonstrated good protection for steel cathodes. In tap water environment the anode weight loss was negligible. The zinc anode suffered intergranular corrosion in sodium chloride environment and this was noticed starting at 40 degree centigrade. In tap water environment the zinc anode demonstrated interesting behavior beyond 60 degree centigrade, that could be attributed to the phenomenon of reversal of potential at elevated temperatures. It also showed shallow pitting spots in tap water environment without any sign of intergranular corrosion. Zinc anodes would suffer intergranular corrosion at high temperatures. (author)

  14. Solid-state tap-changer of transformers: Design, control and implementation

    Energy Technology Data Exchange (ETDEWEB)

    Faiz, Jawad; Siahkolah, Behzad [Center of Excellence on Applied Electromagnetic Systems, School of Electrical and Computer Engineering, University of Tehran, Tehran 1439957131 (Iran, Islamic Republic of)

    2011-02-15

    This paper presents the implementation of a prototype electronic tap-changer of transformer. Mechanical tap-changer has many problems such as low operating speed, short lifetime and heavy size. In order to solve these problems a fully solid-state tap-changer with a new control strategy and optimal configuration is proposed. The design of tap-changer is discussed and bi-directional solid-state power electronics switches are implemented. Following the realization of the tap-changer controller, developed software for such precise control is introduced. To verify the design procedure and optimal configuration and apply the developed software, a prototype low-power tap-changer has been built and tested. (author)

  15. Impact analysis of tap switch out of step for converter transformer

    Science.gov (United States)

    Hong-yue, ZHANG; Zhen-hua, ZHANG; Zhang-xue, XIONG; Gao-wang, YU

    2017-06-01

    AC transformer load regulation is mainly used to adjust the load side voltage level, improve the quality of power supply, the voltage range is relatively narrow. In DC system, converter transformer is the core equipment of AC and DC power converter and inverter. converter transformer tap adjustment can maintain the normal operation of the converter in small angle range control, the absorption of reactive power, economic operation, valve less stress, valve damping circuit loss, AC / DC harmonic component is also smaller. In this way, the tap switch action is more frequent, and a large range of the tap switch adjustment is required. Converter transformer with a more load voltage regulation switch, the voltage regulation range of the switch is generally 20~30%, the adjustment of each file is 1%~2%. Recently it is often found that the tap switch of Converter Transformers is out of step in Converter station. In this paper, it is analyzed in detail the impact of tap switch out of step for differential protection, overexcitation protection and zero sequence over current protection. Analysis results show that: the tap switch out of step has no effect on the differential protection and the overexcitation protection including the tap switch. But the tap switch out of step has effect on zero sequence overcurrent protection of out of step star-angle converter transformer. The zero sequence overcurrent protection will trip when the tap switch out of step is greater than 3 for out of step star-angle converter transformer.

  16. Synchronized tapping facilitates learning sound sequences as indexed by the P300.

    Science.gov (United States)

    Kamiyama, Keiko S; Okanoya, Kazuo

    2014-01-01

    The purpose of the present study was to determine whether and how single finger tapping in synchrony with sound sequences contributed to the auditory processing of them. The participants learned two unfamiliar sound sequences via different methods. In the tapping condition, they learned an auditory sequence while they tapped in synchrony with each sound onset. In the no tapping condition, they learned another sequence while they kept pressing a key until the sequence ended. After these learning sessions, we presented the two melodies again and recorded event-related potentials (ERPs). During the ERP recordings, 10% of the tones within each melody deviated from the original tones. An analysis of the grand average ERPs showed that deviant stimuli elicited a significant P300 in the tapping but not in the no-tapping condition. In addition, the significance of the P300 effect in the tapping condition increased as the participants showed highly synchronized tapping behavior during the learning sessions. These results indicated that single finger tapping promoted the conscious detection and evaluation of deviants within the learned sequences. The effect was related to individuals' musical ability to coordinate their finger movements along with external auditory events.

  17. A statistical characterization of the finger tapping test: modeling, estimation, and applications.

    Science.gov (United States)

    Austin, Daniel; McNames, James; Klein, Krystal; Jimison, Holly; Pavel, Misha

    2015-03-01

    Sensory-motor performance is indicative of both cognitive and physical function. The Halstead-Reitan finger tapping test is a measure of sensory-motor speed commonly used to assess function as part of a neuropsychological evaluation. Despite the widespread use of this test, the underlying motor and cognitive processes driving tapping behavior during the test are not well characterized or understood. This lack of understanding may make clinical inferences from test results about health or disease state less accurate because important aspects of the task such as variability or fatigue are unmeasured. To overcome these limitations, we enhanced the tapper with a sensor that enables us to more fully characterize all the aspects of tapping. This modification enabled us to decompose the tapping performance into six component phases and represent each phase with a set of parameters having clear functional interpretation. This results in a set of 29 total parameters for each trial, including change in tapping over time, and trial-to-trial and tap-to-tap variability. These parameters can be used to more precisely link different aspects of cognition or motor function to tapping behavior. We demonstrate the benefits of this new instrument with a simple hypothesis-driven trial comparing single and dual-task tapping.

  18. Transversus abdominal plane (TAP block for postoperative pain management: a review [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Jan Jakobsson

    2015-11-01

    Full Text Available Transversus abdominal plane (TAP block has a long history and there is currently extensive clinical experience around TAP blocks. The aim of this review is to provide a summary of the present evidence on the effects of TAP block and to provide suggestions for further studies. There are several approaches to performing abdominal wall blocks, with the rapid implementation of ultrasound-guided technique facilitating a major difference in TAP block performance. During surgery, an abdominal wall block may also be applied by the surgeon from inside the abdominal cavity. Today, there are more than 11 meta-analyses providing a compiled evidence base around the effects of TAP block. These analyses include different procedures, different techniques of TAP block administration and, importantly, they compare the TAP block with a variety of alternative analgesic regimes. The effects of TAP block during laparoscopic cholecystectomy seem to be equivalent to local infiltration analgesia and also seem to be beneficial during laparoscopic colon resection. The effects of TAP are more pronounced when it is provided prior to surgery and these effects are local anaesthesia dose-dependent. TAP block seems an interesting alternative in patients with, for example, severe obesity where epidural or spinal anaesthesia/analgesia is technically difficult and/or poses a risk. There is an obvious need for further high-quality studies comparing TAP block prior to surgery with local infiltration analgesia, single-shot spinal analgesia, and epidural analgesia. These studies should be procedure-specific and the effects should be evaluated, both regarding short-term pain and analgesic requirement and also including the effects on postoperative nausea and vomiting, recovery of bowel function, ambulation, discharge, and protracted recovery outcomes (assessed by e.g., postoperative quality of recovery scale.

  19. Transversus abdominal plane (TAP) block for postoperative pain management: a review.

    Science.gov (United States)

    Jakobsson, Jan; Wickerts, Liselott; Forsberg, Sune; Ledin, Gustaf

    2015-01-01

    Transversus abdominal plane (TAP) block has a long history and there is currently extensive clinical experience around TAP blocks. The aim of this review is to provide a summary of the present evidence on the effects of TAP block and to provide suggestions for further studies. There are several approaches to performing abdominal wall blocks, with the rapid implementation of ultrasound-guided technique facilitating a major difference in TAP block performance. During surgery, an abdominal wall block may also be applied by the surgeon from inside the abdominal cavity. Today, there are more than 11 meta-analyses providing a compiled evidence base around the effects of TAP block. These analyses include different procedures, different techniques of TAP block administration and, importantly, they compare the TAP block with a variety of alternative analgesic regimes. The effects of TAP block during laparoscopic cholecystectomy seem to be equivalent to local infiltration analgesia and also seem to be beneficial during laparoscopic colon resection. The effects of TAP are more pronounced when it is provided prior to surgery and these effects are local anaesthesia dose-dependent. TAP block seems an interesting alternative in patients with, for example, severe obesity where epidural or spinal anaesthesia/analgesia is technically difficult and/or poses a risk. There is an obvious need for further high-quality studies comparing TAP block prior to surgery with local infiltration analgesia, single-shot spinal analgesia, and epidural analgesia. These studies should be procedure-specific and the effects should be evaluated, both regarding short-term pain and analgesic requirement and also including the effects on postoperative nausea and vomiting, recovery of bowel function, ambulation, discharge, and protracted recovery outcomes (assessed by e.g., postoperative quality of recovery scale).

  20. Astronomy on Tap as a Professional Development Tool

    Science.gov (United States)

    Rice, Emily; Burtnyk, Kimberly; Silverman, Jeffrey; Popinchalk, Mark; Constellation of Astronomy On Tap Host Stars

    2018-01-01

    We lured scientists, educators, and other astronomy enthusiasts into bars around the world with promises of fun public outreach, but we secretly provided them with networking opportunities and taught them how to be better communicators! Astronomy on Tap (AoT) events began in New York City in 2013, and since then nearly 400 events (featuring 1-6 presenters each) have been organized by over 100 people in over 30 locations across the U.S. and around the world. Implicit in the design of typical AoT events are opportunities for professional development in several areas, most prominently in networking and science communication. We surveyed organizers and presenters to assess the extent to which they have benefited from these opportunities. We report results from that survey and present plans for codifying professional development aspects of AoT events for future implementation.

  1. Force reconstruction from tapping mode force microscopy experiments

    International Nuclear Information System (INIS)

    Payam, Amir F; Martin-Jimenez, Daniel; Garcia, Ricardo

    2015-01-01

    Fast, accurate, and robust nanomechanical measurements are intensely studied in materials science, applied physics, and molecular biology. Amplitude modulation force microscopy (tapping mode) is the most established nanoscale characterization technique of surfaces for air and liquid environments. However, its quantitative capabilities lag behind its high spatial resolution and robustness. We develop a general method to transform the observables into quantitative force measurements. The force reconstruction algorithm has been deduced on the assumption that the observables (amplitude and phase shift) are slowly varying functions of the tip–surface separation. The accuracy and applicability of the method is validated by numerical simulations and experiments. The method is valid for liquid and air environments, small and large free amplitudes, compliant and rigid materials, and conservative and non-conservative forces. (paper)

  2. Landmine detection using two-tapped joint orthogonal matching pursuits

    Science.gov (United States)

    Goldberg, Sean; Glenn, Taylor; Wilson, Joseph N.; Gader, Paul D.

    2012-06-01

    Joint Orthogonal Matching Pursuits (JOMP) is used here in the context of landmine detection using data obtained from an electromagnetic induction (EMI) sensor. The response from an object containing metal can be decomposed into a discrete spectrum of relaxation frequencies (DSRF) from which we construct a dictionary. A greedy iterative algorithm is proposed for computing successive residuals of a signal by subtracting away the highest matching dictionary element at each step. The nal condence of a particular signal is a combination of the reciprocal of this residual and the mean of the complex component. A two-tap approach comparing signals on opposite sides of the geometric location of the sensor is examined and found to produce better classication. It is found that using only a single pursuit does a comparable job, reducing complexity and allowing for real-time implementation in automated target recognition systems. JOMP is particularly highlighted in comparison with a previous EMI detection algorithm known as String Match.

  3. How Well Do Computer-Generated Faces Tap Face Expertise?

    Directory of Open Access Journals (Sweden)

    Kate Crookes

    Full Text Available The use of computer-generated (CG stimuli in face processing research is proliferating due to the ease with which faces can be generated, standardised and manipulated. However there has been surprisingly little research into whether CG faces are processed in the same way as photographs of real faces. The present study assessed how well CG faces tap face identity expertise by investigating whether two indicators of face expertise are reduced for CG faces when compared to face photographs. These indicators were accuracy for identification of own-race faces and the other-race effect (ORE-the well-established finding that own-race faces are recognised more accurately than other-race faces. In Experiment 1 Caucasian and Asian participants completed a recognition memory task for own- and other-race real and CG faces. Overall accuracy for own-race faces was dramatically reduced for CG compared to real faces and the ORE was significantly and substantially attenuated for CG faces. Experiment 2 investigated perceptual discrimination for own- and other-race real and CG faces with Caucasian and Asian participants. Here again, accuracy for own-race faces was significantly reduced for CG compared to real faces. However the ORE was not affected by format. Together these results signal that CG faces of the type tested here do not fully tap face expertise. Technological advancement may, in the future, produce CG faces that are equivalent to real photographs. Until then caution is advised when interpreting results obtained using CG faces.

  4. RoboTAP: Target priorities for robotic microlensing observations

    Science.gov (United States)

    Hundertmark, M.; Street, R. A.; Tsapras, Y.; Bachelet, E.; Dominik, M.; Horne, K.; Bozza, V.; Bramich, D. M.; Cassan, A.; D'Ago, G.; Figuera Jaimes, R.; Kains, N.; Ranc, C.; Schmidt, R. W.; Snodgrass, C.; Wambsganss, J.; Steele, I. A.; Mao, S.; Ment, K.; Menzies, J.; Li, Z.; Cross, S.; Maoz, D.; Shvartzvald, Y.

    2018-01-01

    Context. The ability to automatically select scientifically-important transient events from an alert stream of many such events, and to conduct follow-up observations in response, will become increasingly important in astronomy. With wide-angle time domain surveys pushing to fainter limiting magnitudes, the capability to follow-up on transient alerts far exceeds our follow-up telescope resources, and effective target prioritization becomes essential. The RoboNet-II microlensing program is a pathfinder project, which has developed an automated target selection process (RoboTAP) for gravitational microlensing events, which are observed in real time using the Las Cumbres Observatory telescope network. Aims: Follow-up telescopes typically have a much smaller field of view compared to surveys, therefore the most promising microlensing events must be automatically selected at any given time from an annual sample exceeding 2000 events. The main challenge is to select between events with a high planet detection sensitivity, with the aim of detecting many planets and characterizing planetary anomalies. Methods: Our target selection algorithm is a hybrid system based on estimates of the planet detection zones around a microlens. It follows automatic anomaly alerts and respects the expected survey coverage of specific events. Results: We introduce the RoboTAP algorithm, whose purpose is to select and prioritize microlensing events with high sensitivity to planetary companions. In this work, we determine the planet sensitivity of the RoboNet follow-up program and provide a working example of how a broker can be designed for a real-life transient science program conducting follow-up observations in response to alerts; we explore the issues that will confront similar programs being developed for the Large Synoptic Survey Telescope (LSST) and other time domain surveys.

  5. Perineal tap water burns in the elderly: at what cost?

    Science.gov (United States)

    Potter, Michael D E; Maitz, Peter K M; Kennedy, Peter J; Goltsman, David

    2017-11-01

    Burn injuries are expensive to treat. Burn injuries have been found to be difficult to treat in elderly patients than their younger counterparts. This is likely to result in higher financial burden on the healthcare system; however, no population-specific study has been conducted to ascertain the inpatient treatment costs of elderly patients with hot tap water burns. Six elderly patients (75-92 years) were admitted for tap water burns at Concord Hospital during 2010. All costs incurred during their hospitalization were followed prospectively, and were apportioned into 'direct' and 'indirect' costs. Direct costs encompassed directly measurable costs, such as consumables used on the ward or in theatres, and indirect costs included hospital overheads, such as bed and theatre costs. Three males and three females admitted with burns to the buttocks, legs or feet. Total burn surface area (TBSA) ranged from 9-21% (mean 12.8%). Length of stay ranged from 26-98 days (mean 46 days). One patient died, and four required surgical management or grafting. Total inpatient costs ranged from $69 782.33 to $254 652.70 per patient (mean $122 800.20, standard deviation $67 484.46). TBSA was directly correlated with length of stay (P < 0.01) and total cost (P < 0.01). Hot water burns among the elderly are associated with high treatment costs, which are proportional to the size of the burn. The cost of treating this cohort is higher than previously reported in a general Australian burn cohort. © 2016 Royal Australasian College of Surgeons.

  6. Beam polarimetry in the CBELSA/TAPS experiment

    International Nuclear Information System (INIS)

    Kammer, Susanne

    2010-01-01

    In the identification of nucleon resonances polarization observables play an important role. For the photoproduction experiments of the CBELAS/TAPS assembly at the accelerator facility ELSA in the framework of this thesis linearly and circularly polarized were realized and prepared. Linearly polarized photons were produced on a diamond crystal under usage of the coherent bremsstrahlung. By alignment of the crystal in the bremsstrahlung coherent intensity increasements in form of pronounced edges could be generated. The number of the polarized photons lying in the increasement determines in comparison to the incoherently produced background the degree of polarization. The position of the coherent edge could be tuned by means of control distributions to an arbitrary position in the measured energy spectrum as well as the degree of polarization of the photons optimized. For the production of circularly polarized photons longitudinally polarized electrons on the bremsstrahlung target are required. The polarization transfer of the bremsstrahlung process is uniquely given by the QED, so that the degree of polarization of the photons can be determined via a measurement of the electron-beam polarization. With this goal a for the first time in the CBELSA/TAPS applied momentum-selecting Moeller polarimeter was developed and integrated in the photon-tagging facility. Via a change of the beam helicity the counting-rate asymmetry for parallely and antiparallely beam and target electrons was measured and the degree of polarization of the electrons at beam energies of 2350 MeV determined to typically above 60%. By means of dedicated test measurements and simulations the functionality of the Moeller polarimeter was checked and the relative systematic uncertainty determined to 1%. Since 2007 the Moeller polarimeter essential for the double-polarization experiments is in current operation. Finally a method was sketched, in which via the known cross-section asymmetry of the

  7. Expanding the Universe of "Astronomy on Tap" Public Outreach Events

    Science.gov (United States)

    Rice, Emily L.; Levine, Brian; Livermore, Rachael C.; Silverman, Jeffrey M.; LaMassa, Stephanie M.; Tyndall, Amy; Muna, Demitri; Garofali, Kristen; Morris, Brett; Byler, Nell; Fyhrie, Adalyn; Rehnberg, Morgan; Hart, Quyen N.; Connelly, Jennifer L.; Silvia, Devin W.; Morrison, Sarah J.; Agarwal, Bhaskar; Tremblay, Grant; Schwamb, Megan E.

    2016-01-01

    Astronomy on Tap (AoT, astronomyontap.org) is free public outreach event featuring engaging science presentations in bars, often combined with music, games, and prizes, to encourage a fun, interactive atmosphere. AoT events feature several short astronomy-related presentations primarily by local professional scientists, but also by visiting scientists, students, educators, amatuer astronomers, writers, and artists. Events are held in social venues (bars, coffee shops, art galleries, etc.) in order to bring science directly to the public in a relaxed, informal atmosphere. With this we hope to engage a more diverse audience than typical lectures at academic and cultural institutions and to develop enthusiasm for science among voting, tax-paying adults. The flexible format and content of an AoT event is easy to adapt and expand based on the priorities, resources, and interests of local organizers. The social nature of AoT events provides important professional development and networking opportunities in science communication. Since the first New York City event in April 2013, Astronomy on Tap has expanded to more than ten cities globally, including monthly events in NYC, Austin, Seattle, and Tucson; semi-regular events in Columbus, New Haven, Santiago, Toronto, and Denver; occasional (so far) events in Rochester (NY), Baltimore, Lansing, and Washington, DC; and one-off events in Chicago and Taipei. Several venues regularly attract audiences of over 200 people. We have received media coverage online, in print, and occasionally even on radio and television. In this poster we describe the overarching goals and characteristics of AoT events, distinct adaptations of various locations, resources we have developed, and the methods we use to coordinate among the worldwide local organizers.

  8. Tap to Togetherness: An Innovative Family Relationship Program Reaches Ghana, Africa

    Science.gov (United States)

    Pentz, Julie L.

    2017-01-01

    Tap to Togetherness is a unique program designed to build and enhance family relationships through tap dance steps. Kansas State University researchers from the School of Music, Theatre and Dance and the College of Human Ecology, led by Julie L. Pentz, Associate Professor of Dance, Director of the K-State Dance Program, developed the program.…

  9. On-load Tap Changer Diagnosis on High-Voltage Power Transformers using Dynamic Resistance Measurements

    NARCIS (Netherlands)

    Erbrink, J.J.

    2011-01-01

    High-voltage transformers have tap changers to regulate the voltage in the high-voltage network when the load changes. Those tap changers are subject to different degradation mechanisms and need regular maintenance. Various defects, like contact degradation, often remain undetected and the

  10. Persistent suppression of subthalamic beta-band activity during rhythmic finger tapping in Parkinson's disease.

    Science.gov (United States)

    Joundi, Raed A; Brittain, John-Stuart; Green, Alex L; Aziz, Tipu Z; Brown, Peter; Jenkinson, Ned

    2013-03-01

    The function of synchronous oscillatory activity at beta band (15-30Hz) frequencies within the basal ganglia is unclear. Here we sought support for the hypothesis that beta activity has a global function within the basal ganglia and is not directly involved in the coding of specific biomechanical parameters of movement. We recorded local field potential activity from the subthalamic nuclei of 11 patients with Parkinson's disease during a synchronized tapping task at three different externally cued rates. Beta activity was suppressed during tapping, reaching a minimum that differed little across the different tapping rates despite an increase in velocity of finger movements. Thus beta power suppression was independent of specific motor parameters. Moreover, although beta oscillations remained suppressed during all tapping rates, periods of resynchronization between taps were markedly attenuated during high rate tapping. As such, a beta rebound above baseline between taps at the lower rates was absent at the high rate. Our results demonstrate that beta desynchronization in the region of the subthalamic nucleus is independent of motor parameters and that the beta resynchronization is differentially modulated by rate of finger tapping, These findings implicate consistent beta suppression in the facilitation of continuous movement sequences. Copyright © 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  11. TAPS experiments at Ganil: new developments, on-line results and data processing

    International Nuclear Information System (INIS)

    Lautridou, P.; Lefevre, F.; Marques, M.; Matulewicz, T.; Ostendorf, R.; Quebert, J.; Schutz, Y.

    1993-01-01

    The purpose of the present contribution is to show what the status of data analysis is only three months after TAPS has left GANIL. The authors also described briefly the data analysis package, they presently use and which has been specially developped for the TAPS experiments. One should notice that this package can be easily modified to suit any experimental situation. 8 figs

  12. 7 CFR 760.102 - Administration of ELAP, LFP, LIP, SURE, and TAP.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Administration of ELAP, LFP, LIP, SURE, and TAP. 760.102 Section 760.102 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE... TAP. (a) The programs in subparts C through H of this part will be administered under the general...

  13. Quantifying Parkinson's disease finger-tapping severity by extracting and synthesizing finger motion properties.

    Science.gov (United States)

    Sano, Yuko; Kandori, Akihiko; Shima, Keisuke; Yamaguchi, Yuki; Tsuji, Toshio; Noda, Masafumi; Higashikawa, Fumiko; Yokoe, Masaru; Sakoda, Saburo

    2016-06-01

    We propose a novel index of Parkinson's disease (PD) finger-tapping severity, called "PDFTsi," for quantifying the severity of symptoms related to the finger tapping of PD patients with high accuracy. To validate the efficacy of PDFTsi, the finger-tapping movements of normal controls and PD patients were measured by using magnetic sensors, and 21 characteristics were extracted from the finger-tapping waveforms. To distinguish motor deterioration due to PD from that due to aging, the aging effect on finger tapping was removed from these characteristics. Principal component analysis (PCA) was applied to the age-normalized characteristics, and principal components that represented the motion properties of finger tapping were calculated. Multiple linear regression (MLR) with stepwise variable selection was applied to the principal components, and PDFTsi was calculated. The calculated PDFTsi indicates that PDFTsi has a high estimation ability, namely a mean square error of 0.45. The estimation ability of PDFTsi is higher than that of the alternative method, MLR with stepwise regression selection without PCA, namely a mean square error of 1.30. This result suggests that PDFTsi can quantify PD finger-tapping severity accurately. Furthermore, the result of interpreting a model for calculating PDFTsi indicated that motion wideness and rhythm disorder are important for estimating PD finger-tapping severity.

  14. Finger tapping and pre-attentive sensorimotor timing in adults with ADHD.

    Science.gov (United States)

    Hove, Michael J; Gravel, Nickolas; Spencer, Rebecca M C; Valera, Eve M

    2017-12-01

    Sensorimotor timing deficits are considered central to attention-deficit/hyperactivity disorder (ADHD). However, the tasks establishing timing impairments often involve interconnected processes, including low-level sensorimotor timing and higher level executive processes such as attention. Thus, the source of timing deficits in ADHD remains unclear. Low-level sensorimotor timing can be isolated from higher level processes in a finger-tapping task that examines the motor response to unexpected shifts of metronome onsets. In this study, adults with ADHD and ADHD-like symptoms (n = 25) and controls (n = 26) performed two finger-tapping tasks. The first assessed tapping variability in a standard tapping task (metronome-paced and unpaced). In the other task, participants tapped along with a metronome that contained unexpected shifts (±15, 50 ms); the timing adjustment on the tap following the shift captures pre-attentive sensorimotor timing (i.e., phase correction) and thus should be free of potential higher order confounds (e.g., attention). In the standard tapping task, as expected, the ADHD group had higher timing variability in both paced and unpaced tappings. However, in the pre-attentive task, performance did not differ between the ADHD and control groups. Together, results suggest that low-level sensorimotor timing and phase correction are largely preserved in ADHD and that some timing impairments observed in ADHD may stem from higher level factors (such as sustained attention).

  15. Follow You, Follow  Me: Continuous Mutual Prediction and Adaptation in Joint Tapping

    DEFF Research Database (Denmark)

    Konvalinka, Ivana; Vuust, Peter; Roepstorff, Andreas

    2010-01-01

    both were hearing each other, the pair became a coupled, mutually and continuously adaptive unit of two “hyper-followers”, with their intertap intervals (ITIs) oscillating in opposite directions on a tap-to-tap basis. There was thus no evidence for the emergence of a leader–follower strategy. We also...

  16. Tapping but not massage enhances vasodilation and improves venous palpation of cutaneous veins.

    Science.gov (United States)

    Ichimura, Mika; Sasaki, Shinsuke; Mori, Masaharu; Ogino, Tetsuya

    2015-01-01

    This paper investigated whether tapping on the median cubital vein or massaging the forearm was more effective in obtaining better venous palpation for venipuncture. Forty healthy volunteers in their twenties were subjected to tapping (10 times in 5 sec) or massage (10 strokes in 20 sec from the wrist to the cubital fossa) under tourniquet inflation on the upper arm. Venous palpation was assessed using the venous palpation score (0-6, with 0 being impalpable). Three venous factors-venous depth, cross-sectional area, and elevation-were also measured using ultrasonography. The venous palpation score increased significantly by tapping but not by massage. Moreover, all 3 venous measurements changed significantly by tapping, while only the depth decreased significantly by massage. The three venous measurements correlated significantly with the venous palpation score, indicating that they are useful objective indicators for evaluating vasodilation. We suggest that tapping is an effective vasodilation technique.

  17. TouchGrid: Touchpad pointing by recursively mapping taps to smaller display regions

    DEFF Research Database (Denmark)

    Hertzum, Morten; Hornbæk, Kasper

    2005-01-01

    Touchpad devices are widely used but lacking in pointing efficiency. The TouchGrid, an instance of what we term cell cursors, replaces moving the cursor through dragging the finger on a touchpad with tapping in different regions of the touchpad. The touchpad regions are recursively mapped...... to smaller display regions and thereby enable high-precision pointing without requiring high tapping precision. In an experiment, six subjects used the TouchGrid and a standard touchpad across different numbers of targets, distances to targets, and target widths. Whereas standard touchpad operation follows...... Fitts’ law, target selection time with the TouchGrid is a linear function of the required number of taps. The TouchGrid was significantly faster for small targets and for tasks requiring one tap, and marginally faster for two-tap tasks. Error rates tended to be higher with the TouchGrid than...

  18. Association between finger tapping, attention, memory, and cognitive diagnosis in elderly patients.

    Science.gov (United States)

    Rabinowitz, Israel; Lavner, Yizhar

    2014-08-01

    This study examined the association between spontaneous finger tapping and cognitive function, with a detailed analysis of the two main phases of finger tapping, the touch-phase and the off-phase. 170 elderly patients (83 men, 87 women; M age = 82.1 yr., SD = 6.2) underwent cognitive assessment including the Mini-Mental State Examination, a forward digit span test, and 15 sec. of finger tapping. Results indicated a significant increase in the length and variability of the finger-touch phase among participants with mild cognitive impairment or dementia compared to participants with no cognitive impairment, suggesting a relationship between finger tapping and attention, short-term memory, and cognitive diagnosis. Pattern classification analyses on the finger tapping parameters indicated a specificity of 0.91 and sensitivity of 0.52 for ruling out cognitive impairment.

  19. HIGH PERFORMANCE TAPS FOR CUTTING THREADS IN DIFFICULT TO MACHINE MATERIALS

    Directory of Open Access Journals (Sweden)

    M. R. Akhmedova

    2016-01-01

    Full Text Available Objectives. This article explores in detail questions of instrument operation function of tapping internal threads in hard materials. The existing relationship between vibration system amplitude and tool durability is indicated; on this basis, it is determined that the best course for improving the durability performance is increasing vibratory resistance. Based on a critical analysis of existing designs with consideration of their flaws, the development of new technological designs of taps is tasked with ensuring stable operation when handling hard materials. Methods. It is noteworthy that one of the main vibration resistance improvement methods of the tool is to reduce the contact area of the tool with the work piece in the cutting zone. Methods are proposed for improving the vibration resistance of taps, considering the correlation adjustment of tap teeth in order to completely eliminate friction at the sides of the thread cutting surface and uneven implementation flute cutting steps. Results. The idea of increasing vibration resistance has seen the new development of vibration-proof tap designs, heralded as innovations due to the accuracy of thread cutting and durability achieved by reducing the thread contact area with the work piece in the cutting zone. Increased vibration resistance is achieved in the modified taps through high correction by means of thread side downgrading of the coarse tap cone by an additional angle of 30º. In another design, the stylus provided with uneven angular spacing. Test results of designed taps machined in corrosion-resistant 1Kh18N9T steel. A manifold increase in tool durability was achieved due to its high vibration resistance. Conclusions. The redesigned taps have a number of advantages, characterised by a high resistance when processing difficult materials and an insignificant increase in the complexity of their manufacture compared with standard taps. Therefore they can be recommended for large

  20. TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice.

    Directory of Open Access Journals (Sweden)

    Daniel Kolbus

    Full Text Available Antigen presenting cells (APC have the ability to present both extra-cellular and intra-cellular antigens via MHC class I molecules to CD8(+ T cells. The cross presentation of extra-cellular antigens is reduced in mice with deficient Antigen Peptide Transporter 1 (TAP1-dependent MHC class I antigen presentation, and these mice are characterized by a diminished CD8(+ T cell population. We have recently reported an increased activation of CD8(+ T cells in hypercholesterolemic Apoe(-/- mice. Therefore, this study included TAP1-deficient Apoe(-/- mice (Apoe(-/-Tap1(-/- to test the atherogenicity of CD8(+ T cells and TAP1-dependent cross presentation in a hypercholesterolemic environment. As expected the CD8(+ T cell numbers were low in Apoe(-/-Tap1(-/- mice in comparison to Apoe(-/- mice, constituting ~1% of the lymphocyte population. In spite of this there were no differences in the extent of atherosclerosis as assessed by en face Oil Red O staining of the aorta and cross-sections of the aortic root between Apoe(-/-Tap1(-/- and Apoe(-/- mice. Moreover, no differences were detected in lesion infiltration of macrophages or CD3(+ T cells in Apoe(-/-Tap1(-/- compared to Apoe(-/- mice. The CD3(+CD4(+ T cell fraction was increased in Apoe(-/-Tap1(-/- mice, suggesting a compensation for the decreased CD8(+ T cell population. Interestingly, the fraction of CD8(+ effector memory T cells was increased but this appeared to have little impact on the atherosclerosis development.In conclusion, Apoe(-/-Tap1(-/- mice develop atherosclerosis equal to Apoe(-/- mice, indicating a minor role for CD8(+ T cells and TAP1-dependent antigen presentation in the disease process.

  1. Tap Arduino: An Arduino microcontroller for low-latency auditory feedback in sensorimotor synchronization experiments.

    Science.gov (United States)

    Schultz, Benjamin G; van Vugt, Floris T

    2016-12-01

    Timing abilities are often measured by having participants tap their finger along with a metronome and presenting tap-triggered auditory feedback. These experiments predominantly use electronic percussion pads combined with software (e.g., FTAP or Max/MSP) that records responses and delivers auditory feedback. However, these setups involve unknown latencies between tap onset and auditory feedback and can sometimes miss responses or record multiple, superfluous responses for a single tap. These issues may distort measurements of tapping performance or affect the performance of the individual. We present an alternative setup using an Arduino microcontroller that addresses these issues and delivers low-latency auditory feedback. We validated our setup by having participants (N = 6) tap on a force-sensitive resistor pad connected to the Arduino and on an electronic percussion pad with various levels of force and tempi. The Arduino delivered auditory feedback through a pulse-width modulation (PWM) pin connected to a headphone jack or a wave shield component. The Arduino's PWM (M = 0.6 ms, SD = 0.3) and wave shield (M = 2.6 ms, SD = 0.3) demonstrated significantly lower auditory feedback latencies than the percussion pad (M = 9.1 ms, SD = 2.0), FTAP (M = 14.6 ms, SD = 2.8), and Max/MSP (M = 15.8 ms, SD = 3.4). The PWM and wave shield latencies were also significantly less variable than those from FTAP and Max/MSP. The Arduino missed significantly fewer taps, and recorded fewer superfluous responses, than the percussion pad. The Arduino captured all responses, whereas at lower tapping forces, the percussion pad missed more taps. Regardless of tapping force, the Arduino outperformed the percussion pad. Overall, the Arduino is a high-precision, low-latency, portable, and affordable tool for auditory experiments.

  2. An in-home video study and questionnaire survey of food preparation, kitchen sanitation, and hand washing practices.

    Science.gov (United States)

    Scott, Elizabeth; Herbold, Nancie

    2010-06-01

    Foodborne illnesses pose a problem to all individuals but are especially significant for infants, the elderly, and individuals with compromised immune systems. Personal hygiene is recognized as the number-one way people can lower their risk. The majority of meals in the U.S. are eaten at home. Little is known, however, about the actual application of personal hygiene and sanitation behaviors in the home. The study discussed in this article assessed knowledge of hygiene practices compared to observed behaviors and determined whether knowledge equated to practice. It was a descriptive study involving a convenience sample of 30 households. Subjects were recruited from the Boston area and a researcher and/or a research assistant traveled to the homes of study participants to videotape a standard food preparation procedure preceded by floor mopping. The results highlight the differences between individuals' reported beliefs and actual practice. This information can aid food safety and other health professionals in targeting food safety education so that consumers understand their own critical role in decreasing their risk for foodborne illness.

  3. Cytomegalovirus Survival and Transferability and the Effectiveness of Common Hand-Washing Agents against Cytomegalovirus on Live Human Hands

    OpenAIRE

    Stowell, Jennifer D.; Forlin-Passoni, Daniela; Radford, Kay; Bate, Sheri L.; Dollard, Sheila C.; Bialek, Stephanie R.; Cannon, Michael J.; Schmid, D. Scott

    2014-01-01

    Congenital cytomegalovirus (CMV) transmission can occur when women acquire CMV while pregnant. Infection control guidelines may reduce risk for transmission. We studied the duration of CMV survival after application of bacteria to the hands and after transfer from the hands to surfaces and the effectiveness of cleansing with water, regular and antibacterial soaps, sanitizer, and diaper wipes. Experiments used CMV AD169 in saliva at initial titers of 1 × 105 infectious particles/ml. Samples fr...

  4. Cytomegalovirus survival and transferability and the effectiveness of common hand-washing agents against cytomegalovirus on live human hands.

    Science.gov (United States)

    Stowell, Jennifer D; Forlin-Passoni, Daniela; Radford, Kay; Bate, Sheri L; Dollard, Sheila C; Bialek, Stephanie R; Cannon, Michael J; Schmid, D Scott

    2014-01-01

    Congenital cytomegalovirus (CMV) transmission can occur when women acquire CMV while pregnant. Infection control guidelines may reduce risk for transmission. We studied the duration of CMV survival after application of bacteria to the hands and after transfer from the hands to surfaces and the effectiveness of cleansing with water, regular and antibacterial soaps, sanitizer, and diaper wipes. Experiments used CMV AD169 in saliva at initial titers of 1 × 10(5) infectious particles/ml. Samples from hands or surfaces (points between 0 and 15 min) were placed in culture and observed for at least 2 weeks. Samples were also tested using CMV real-time PCR. After application of bacteria to the hands, viable CMV was recovered from 17/20 swabs at 0 min, 18/20 swabs at 1 min, 5/20 swabs at 5 min, and 4/20 swabs at 15 min. After transfer, duration of survival was at least 15 min on plastic (1/2 swabs), 5 min on crackers and glass (3/4 swabs), and 1 min or less on metal and cloth (3/4 swabs); no viable virus was collected from wood, rubber, or hands. After cleansing, no viable virus was recovered using water (0/22), plain soap (0/20), antibacterial soap (0/20), or sanitizer (0/22). Viable CMV was recovered from 4/20 hands 10 min after diaper wipe cleansing. CMV remains viable on hands for sufficient times to allow transmission. CMV may be transferred to surfaces with reduced viability. Hand-cleansing methods were effective at eliminating viable CMV from hands.

  5. One Hand Washes Another : Informal Ties Between Organized Criminal Groups and Law-Enforcement Agencies in Russia

    Directory of Open Access Journals (Sweden)

    Alexey Konnov

    2006-11-01

    Full Text Available This article discusses the forms, contents and peculiarities of the existing informal ties between members of organized criminal groups and representatives of law-enforcement agencies in the Tatarstan Republic of Russia. Particular attention is paid to the origins of informal ties; ways how these relations are established, maintained, and utilized by both parts; causes of corruption in the law-enforcement agencies and the possibilities to understand it. The main conclusions are based on the results of ninety-six in-depth interviews with the law-enforcement officers, businessmen, members of organized criminal groups, and journalists conducted in main cities and towns of the Tatarstan Republic under support of the Transnational Crime and Corruption Centre at American University.

  6. Ultrasound guided TAP block versus ultrasound guided caudal block for pain relief in children undergoing lower abdominal surgeries

    Directory of Open Access Journals (Sweden)

    Wafaa Mohamed Alsadek

    2015-04-01

    Conclusion: TAP block and caudal block under ultrasound guidance proved to be safe with no recorded complications either intra or postoperatively. Patient and parent satisfaction was markedly observed in case of TAP block.

  7. Tapping into tongue motion to substitute or augment upper limbs

    Science.gov (United States)

    Ghovanloo, Maysam; Sahadat, M. Nazmus; Zhang, Zhenxuan; Kong, Fanpeng; Sebkhi, Nordine

    2017-05-01

    Assistive technologies (AT) play an important role in the lives of people with disabilities. Most importantly, they allow individuals with severe physical disabilities become more independence. Inherent abilities of the human tongue originated from its strong representation in the motor cortex, its direct connection to the brain through well-protected cranial nerves, and easy access without a surgery have resulted in development of a series of tongue-operated ATs that tap into the dexterous, intuitive, rapid, precise, and tireless motion of the tongue. These ATs not only help people with tetraplegia as a result of spinal cord injury or degenerative neurological diseases to access computers/smartphones, drive wheelchairs, and interact with their environments but also have the potential to enhance rehabilitation paradigms for stroke survivors. In this paper, various types of tongue operated ATs are discussed based on their working principles and task based performances. Comparisons are drawn based on widely accepted and standardized quantitative measures, such as throughput, information transfer rate, typing speed/accuracy, tracking error, navigation period, and navigation accuracy as well as qualitative measures, such as user feedback. Finally, the prospects of using variations of these versatile devices to enhance human performance in environments that limit hand and finger movements, such as space exploration or underwater operations are discussed.

  8. Automatic and objective assessment of alternating tapping performance in Parkinson's disease.

    Science.gov (United States)

    Memedi, Mevludin; Khan, Taha; Grenholm, Peter; Nyholm, Dag; Westin, Jerker

    2013-12-09

    This paper presents the development and evaluation of a method for enabling quantitative and automatic scoring of alternating tapping performance of patients with Parkinson's disease (PD). Ten healthy elderly subjects and 95 patients in different clinical stages of PD have utilized a touch-pad handheld computer to perform alternate tapping tests in their home environments. First, a neurologist used a web-based system to visually assess impairments in four tapping dimensions ('speed', 'accuracy', 'fatigue' and 'arrhythmia') and a global tapping severity (GTS). Second, tapping signals were processed with time series analysis and statistical methods to derive 24 quantitative parameters. Third, principal component analysis was used to reduce the dimensions of these parameters and to obtain scores for the four dimensions. Finally, a logistic regression classifier was trained using a 10-fold stratified cross-validation to map the reduced parameters to the corresponding visually assessed GTS scores. Results showed that the computed scores correlated well to visually assessed scores and were significantly different across Unified Parkinson's Disease Rating Scale scores of upper limb motor performance. In addition, they had good internal consistency, had good ability to discriminate between healthy elderly and patients in different disease stages, had good sensitivity to treatment interventions and could reflect the natural disease progression over time. In conclusion, the automatic method can be useful to objectively assess the tapping performance of PD patients and can be included in telemedicine tools for remote monitoring of tapping.

  9. Arrhythmokinesis is evident during unimanual not bimanual finger tapping in Parkinson's disease.

    Science.gov (United States)

    Trager, Megan H; Velisar, Anca; Koop, Mandy Miller; Shreve, Lauren; Quinn, Emma; Bronte-Stewart, Helen

    2015-01-01

    Arrhythmokinesis, the variability in repetitive movements, is a fundamental feature of Parkinson's disease (PD). We hypothesized that unimanual repetitive alternating finger tapping (AFT) would reveal more arrhythmokinesis compared to bimanual single finger alternating hand tapping (SFT), in PD. The variability of inter-strike interval (CVISI) and of amplitude (CVAMP) during AFT and SFT were measured on an engineered, MRI-compatible keyboard in sixteen PD subjects off medication and in twenty-four age-matched controls. The CVISI and CVAMP of the more affected (MA) and less affected (LA) sides in PD subjects were greater during AFT than SFT (P tapping brings out more arrhythmokinesis compared to bimanual, single finger tapping in PDs but not in controls. Arrhythmokinesis during unimanual, alternating finger tapping captured a significant difference between both the MA and LA hands of PD subjects and controls, whereas that during a bimanual, single finger tapping task only distinguished between the MA hand and controls. Arrhythmokinesis underlies freezing of gait and may also underlie the freezing behavior documented in fine motor control if studied using a unimanual alternating finger tapping task.

  10. Effectiveness of Modal Decomposition for Tapping Atomic Force Microscopy Microcantilevers in Liquid Environment.

    Science.gov (United States)

    Kim, Il Kwang; Lee, Soo Il

    2016-05-01

    The modal decomposition of tapping mode atomic force microscopy microcantilevers in liquid environments was studied experimentally. Microcantilevers with different lengths and stiffnesses and two sample surfaces with different elastic moduli were used in the experiment. The response modes of the microcantilevers were extracted as proper orthogonal modes through proper orthogonal decomposition. Smooth orthogonal decomposition was used to estimate the resonance frequency directly. The effects of the tapping setpoint and the elastic modulus of the sample under test were examined in terms of their multi-mode responses with proper orthogonal modes, proper orthogonal values, smooth orthogonal modes and smooth orthogonal values. Regardless of the stiffness of the microcantilever under test, the first mode was dominant in tapping mode atomic force microscopy under normal operating conditions. However, at lower tapping setpoints, the flexible microcantilever showed modal distortion and noise near the tip when tapping on a hard sample. The stiff microcantilever had a higher mode effect on a soft sample at lower tapping setpoints. Modal decomposition for tapping mode atomic force microscopy can thus be used to estimate the characteristics of samples in liquid environments.

  11. X-ray microtomography study of the compaction process of rods under tapping.

    Science.gov (United States)

    Fu, Yang; Xi, Yan; Cao, Yixin; Wang, Yujie

    2012-05-01

    We present an x-ray microtomography study of the compaction process of cylindrical rods under tapping. The process is monitored by measuring the evolution of the orientational order parameter, local, and overall packing densities as a function of the tapping number for different tapping intensities. The slow relaxation dynamics of the orientational order parameter can be well fitted with a stretched-exponential law with stretching exponents ranging from 0.9 to 1.6. The corresponding relaxation time versus tapping intensity follows an Arrhenius behavior which is reminiscent of the slow dynamics in thermal glassy systems. We also investigated the boundary effect on the ordering process and found that boundary rods order faster than interior ones. In searching for the underlying mechanism of the slow dynamics, we estimated the initial random velocities of the rods under tapping and found that the ordering process is compatible with a diffusion mechanism. The average coordination number as a function of the tapping number at different tapping intensities has also been measured, which spans a range from 6 to 8.

  12. Antibacterial TAP-mimic electrospun polymer scaffold: effects on P. gingivalis-infected dentin biofilm.

    Science.gov (United States)

    Albuquerque, Maria Tereza P; Evans, Joshua D; Gregory, Richard L; Valera, Marcia C; Bottino, Marco C

    2016-03-01

    This study sought to investigate, in vitro, the effects of a recently developed triple antibiotic paste (TAP)-mimic polymer nanofibrous scaffold against Porphyromonas gingivalis-infected dentin biofilm. Dentin specimens (4 × 4 × 1 mm(3)) were prepared from human canines. The specimens were sterilized, inoculated with P. gingivalis (ATCC 33277), and incubated for 1 week to allow for biofilm formation. Infected dentin specimens were exposed for 3 days to the following treatments: antibiotic-free polydioxanone scaffold (PDS, control), PDS + 25 wt% TAP [25 mg of each antibiotic (metronidazole, ciprofloxacin, and minocycline) per mL of the PDS polymer solution], or a saturated TAP-based solution (50 mg of each antibiotic per mL of saline solution). In order to serve as the negative control, infected dentin specimens were left untreated (bacteria only). To determine the antimicrobial efficacy of the TAP-mimic scaffold, a colony-forming unit (CFU) per milliliter (n = 10/group) measurement was performed. Furthermore, additional specimens (n = 2/group) were prepared to qualitatively study biofilm inhibition via scanning electron microscopy (SEM). Statistics were performed, and significance was set at the 5% level. Both the TAP-mimic scaffold and the positive control (TAP solution) led to complete bacterial elimination, differing statistically (p mimic scaffold against an established P. gingivalis-infected dentin biofilm. Collectively, the data suggest that the proposed nanofibrous scaffold might be used as an alternative to the advocated clinical gold standard (i.e., TAP) for intracanal disinfection prior to regenerative endodontics.

  13. Bottled, filtered, and tap water use in Latino and non-Latino children.

    Science.gov (United States)

    Hobson, Wendy L; Knochel, Miguel L; Byington, Carrie L; Young, Paul C; Hoff, Charles J; Buchi, Karen F

    2007-05-01

    To describe bottled, filtered, and tap water consumption and fluoride use among pediatric patients; to analyze differences between ethnic and socioeconomic groups; and to describe the frequency of physician-parent discussions regarding water consumption. Convenience sample survey. An urban public health clinic. Parents attending a public health clinic. The primary outcome measure was the prevalence of tap, filtered, and bottled water use. The secondary outcome measures were supplemental fluoride use and the percentage of patients reporting discussions of water consumption with their physician. A total of 216 parents (80.5% Latino and 19.5% non-Latino) completed the survey. Of the parents, 30.1% never drank tap water and 41.2% never gave it to their children. Latino parents were less likely than non-Latino parents to drink tap water (odds ratio, 0.26; 95% confidence interval, 0.10-0.67) and less likely to give tap water to their children (odds ratio, 0.32; 95% confidence interval, 0.15-0.70). More Latinos believed that tap water would make them sick (odds ratio, 5.63; 95% confidence interval, 2.17-14.54). Approximately 40% of children who never drank tap water were not receiving fluoride supplements. Of the lowest-income families (water to their children. Of the parents surveyed, 82.5% reported that their child's physician had never discussed the type of water they should use. Many Latino families avoid drinking tap water because they fear it causes illness. Unnecessary use of bottled and filtered water is costly and may result in adverse dental health outcomes. Physicians should provide guidance to families regarding the safety, low cost, and dental health benefits of drinking tap water.

  14. CSF tapping also improves mental imagery of gait in normal pressure hydrocephalus.

    Science.gov (United States)

    Marques, Bruno; Laidet, Magali; Armand, Stéphane; Assal, Frédéric; Allali, Gilles

    2017-11-01

    This study aims to compare the changes of Timed Up and Go (TUG) and its imagined version (iTUG) after CSF tapping between patients with idiopathic normal pressure hydrocephalus (iNPH) and its mimics. TUG and iTUG were performed before and 24 h after CSF tapping in 117 patients (75.8 ± 6.9 years; 35% female) with suspicion of iNPH (68 iNPH and 49 mimics). Mental imagery of locomotion was modified after CSF tapping in iNPH patients, but not in the mimics.

  15. The occurrence of antibiotic resistance genes in tap water - a review

    Science.gov (United States)

    Siedlecka, Agata

    2018-02-01

    The study presents a review of the occurrence of genetic determinants of antibiotic resistance in tap water. The aim of this study was also to compare the applied methods for antibiotic resistance genes (ARGs) investigations in tap water. As the concentration of ARGs in treated, drinking water is expected to be very low and may cause problems in a standard isolation procedure, the special emphasis is placed on the applied procedures of DNA extraction and their efficiency. The study presents the first attempts to obtain DNA directly from tap water. Further efforts must be put to determine the final amount of obtained DNA and the presence of chosen ARGs among the molecules.

  16. On the Cutting Performance of Coated HSS Taps When Machining of Austenitic Steel

    Science.gov (United States)

    Sliwkova, Petra; Piska, Miroslav

    2014-12-01

    The paper deals with a quality of the PVD coated HSS taps when cutting the stainless austenitic chromiumnickel non-stabilized steel DIN 1.4301 (X5CrNi 18-10). The main attention is focused on the analysis of loading (cutting moment, specific energy) of the HSS taps by means of pieso-electrical dynamometer Kistler 9272 and the relation between the quality of duplex and triplex PVD coatings and their effects on the quality of machined thread surfaces and tool life of the taps. The results showed a safe and stabilized cutting with acceptable quality of threads for HSSE with the TiN+TiCN+DLC coating.

  17. Primary stability of a hybrid self-tapping implant compared to a cylindrical non-self-tapping implant with respect to drilling protocols in an ex vivo model.

    Science.gov (United States)

    Toyoshima, Takeshi; Wagner, Wilfried; Klein, Marcus Oliver; Stender, Elmar; Wieland, Marco; Al-Nawas, Bilal

    2011-03-01

    Modifications of implant design have been intending to improve primary stability. However, little is known about investigation of a hybrid self-tapping implant on primary stability. The aims of this study were to evaluate the primary stability of two hybrid self-tapping implants compared to one cylindrical non-self-tapping implant, and to elucidate the relevance of drilling protocols on primary stability in an ex vivo model. Two types of hybrid self-tapping implants (Straumann® Bone Level implant [BL], Straumann® Tapered Effect implant [TE]) and one type of cylindrical non-self-tapping implant (Straumann® Standard Plus implant [SP]) were investigated in the study. In porcine iliac cancellous bones, 10 implants each were inserted either using standard drilling or under-dimensioned drilling protocol. The evaluation of implant-bone interface stability was carried out by records of maximum insertion torque, the Periotest® (Siemens, Bensheim, Germany), the resonance frequency analysis (RFA), and the push-out test. In each drilling group, the maximum insertion torque values of BL and TE were significantly higher than SP (p=.014 and p=.047, respectively). In each group, the Periotest values of TE were significantly lower than SP (p=.036 and p=.033, respectively). The Periotest values of BL and TE were significantly lower in the group of under-dimensioned drilling than standard drilling (p=.002 and p=.02, respectively). In the RFA, no statistical significances were found in implants between two groups and between implants in each group. In each group, the push-out values of BL and TE were significantly higher than SP (p=.006 and p=.049, respectively). Hybrid self-tapping implants could achieve a high primary stability which predicts them for use in low-density bone. However, there is still a debate to clarify the influence of under-dimensioned drilling on primary stability. © 2009, Copyright the Authors. Journal Compilation © 2011, Wiley Periodicals, Inc.

  18. Tobacco Industry interference in TAPS policy making in Bulgaria

    Directory of Open Access Journals (Sweden)

    Pavel P Antonov

    2017-05-01

    Full Text Available Tobacco industry (TI has a powerful grasp of politics and the media in Bulgaria, but there is limited knowledge of its methods and communication messages. To explore and analyse them, we are using a recent case from the policy advocacy practice of the Smoke-free Life Coalition, ENSP member in Bulgaria. A mixed social research methodology was employed, involving: a case study; qualitative content analysis of documented communication; ethnographic participant observation; and semi-structured interviews with TAPS advocacy campaigners, policy makers and TI representatives, in the action research tradition. The case study analyses TI reaction to a surprising proposal for a complete ban of tobacco advertising, promotion and sponsorship, submitted to Bulgaria’s Parliament in November 2016 – and consecutively withdrawn. Being involved in all stages of the case and present at meetings between TI and MPs enables the researchers to gather rich information and analyse it, to cast light on: the methods for successful interference with democratic decision making, applied by industry representatives; the specific communication messages and arguments they employ to suppress smoke-free legislation. The paper observes how TI speculates with the interests of different groups, affected by and involved in its operations, to successfully contradict health concerns voiced by MPs. Democratically elected representatives appear unable to uphold the social and health interests of their voters and succumb to TI priorities. The paper concludes that a pro-industry discourse, which favours corporate incomes over concerns for people’s health and life, dominates democratic decision making mechanisms in Bulgaria’s post-socialist political landscape. Funding The Union Against Tuberculosis and Lung Diseases

  19. Long-range correlation in synchronization and syncopation tapping: a linear phase correction model.

    Directory of Open Access Journals (Sweden)

    Didier Delignières

    Full Text Available We propose in this paper a model for accounting for the increase in long-range correlations observed in asynchrony series in syncopation tapping, as compared with synchronization tapping. Our model is an extension of the linear phase correction model for synchronization tapping. We suppose that the timekeeper represents a fractal source in the system, and that a process of estimation of the half-period of the metronome, obeying a random-walk dynamics, combines with the linear phase correction process. Comparing experimental and simulated series, we show that our model allows accounting for the experimentally observed pattern of serial dependence. This model complete previous modeling solutions proposed for self-paced and synchronization tapping, for a unifying framework of event-based timing.

  20. EFFECT OF PILOT HOLE TAPPING ON PULLOUT STRENGTH AND INSERTION TORQUE OF DUAL CORE PEDICLE SCREWS.

    Science.gov (United States)

    Rosa, Rodrigo César; Silva, Patrícia; Falcai, Maurício José; Shimano, Antônio Carlos; Defino, Helton Luiz Aparecido

    2010-01-01

    To evaluate the influence of pilot hole tapping on pullout resistance and insertion torque of pedicle screws with a conical core. Mechanical tests using a universal testing machine were performed on pedicle screws with a conical core that were inserted into pedicles in the fifth lumbar vertebra of calves. The insertion torque was measured using a torque meter with a capacity of 10 Nm, which was considered to be the highest torque value. The pilot holes were prepared using a probe of external diameter 3.8 mm and tapping of the same dimensions and thread characteristics as the screw. Decreased insertion torque and pullout resistance were observed in the group with prior tapping of the pilot hole. Pilot hole tapping reduced the insertion torque and pullout resistance of pedicle screws with a conical core that had been inserted into the pedicle of the fifth lumbar vertebra of calves.

  1. Fast and controlled fabrication of porous graphene oxide: application of AFM tapping for mechano-chemistry

    Science.gov (United States)

    Chu, Liangyong; Korobko, Alexander V.; Bus, Marcel; Boshuizen, Bart; Sudhölter, Ernst J. R.; Besseling, Nicolaas A. M.

    2018-05-01

    This paper describes a novel method to fabricate porous graphene oxide (PGO) from GO by exposure to oxygen plasma. Compared to other methods to fabricate PGO described so far, e.g. the thermal and steam etching methods, oxygen plasma etching method is much faster. We studied the development of the porosity with exposure time using atomic force microscopy (AFM). It was found that the development of PGO upon oxygen-plasma exposure can be controlled by tapping mode AFM scanning using a Si tip. AFM tapping stalls the growth of pores upon further plasma exposure at a level that coincides with the fraction of sp2 carbons in the GO starting material. We suggest that AFM tapping procedure changes the bond structure of the intermediate PGO structure, and these stabilized PGO structures cannot be further etched by oxygen plasma. This constitutes the first report of tapping AFM as a tool for local mechano-chemistry.

  2. Bone scintigraphy, plasma ALP, TAP and PAP in patients with prostatic cancer

    International Nuclear Information System (INIS)

    Imamura, Akihiko; Hoshi, Hiroaki; Jinnouchi, Seishi; Samejima, Masahiko; Watanabe, Katsushi

    1988-01-01

    This study assessed the ability of bone scintigraphy, alkaline phosphatase (ALP), total acid phosphatase (TAP), and prostatic acid phosphatase (PAP) to diagnose bone metastasis in a series of 62 patients with histologically proven prostatic cancer. Abnormal uptake was seen on the bone scan in 49 patients (79 %). A final diagnosis of bone metastasis was made in 40 patients (65 %). The sensitivity and specificity were 100 % and 59 %, respectively, for bone scintigraphy; 50 % and 96 % for ALP; 65 % and 82 % for TAP; and 73 % and 77 % for PAP. For 40 patients with bone metastasis, all of the ALP, TAP, and PAP were positive in 17 patients (43 %) and negative in 8 patients (20 %). Higher levels of ALP, TAP, and PAP tended to be associated with more extensive bone metastasis. Although serological examination showed lower sensitivity than bone scintigraphy in the diagnosis of bone metastasis, PAP may be most frequently used as a screening procedure of bone metastasis. (Namekawa, K.)

  3. Functional analysis of the accessory protein TapA in Bacillus subtilis amyloid fiber assembly.

    Science.gov (United States)

    Romero, Diego; Vlamakis, Hera; Losick, Richard; Kolter, Roberto

    2014-04-01

    Bacillus subtilis biofilm formation relies on the assembly of a fibrous scaffold formed by the protein TasA. TasA polymerizes into highly stable fibers with biochemical and morphological features of functional amyloids. Previously, we showed that assembly of TasA fibers requires the auxiliary protein TapA. In this study, we investigated the roles of TapA sequences from the C-terminal and N-terminal ends and TapA cysteine residues in its ability to promote the assembly of TasA amyloid-like fibers. We found that the cysteine residues are not essential for the formation of TasA fibers, as their replacement by alanine residues resulted in only minor defects in biofilm formation. Mutating sequences in the C-terminal half had no effect on biofilm formation. However, we identified a sequence of 8 amino acids in the N terminus that is key for TasA fiber formation. Strains expressing TapA lacking these 8 residues were completely defective in biofilm formation. In addition, this TapA mutant protein exhibited a dominant negative effect on TasA fiber formation. Even in the presence of wild-type TapA, the mutant protein inhibited fiber assembly in vitro and delayed biofilm formation in vivo. We propose that this 8-residue sequence is crucial for the formation of amyloid-like fibers on the cell surface, perhaps by mediating the interaction between TapA or TapA and TasA molecules.

  4. Tapping of Love waves in an isotropic surface waveguide by surface-to-bulk wave transduction.

    Science.gov (United States)

    Tuan, H.-S.; Chang, C.-P.

    1972-01-01

    A theoretical study of tapping a Love wave in an isotropic microacoustic surface waveguide is given. The surface Love wave is tapped by partial transduction into a bulk wave at a discontinuity. It is shown that, by careful design of the discontinuity, the converted bulk wave power and the radiation pattern may be controlled. General formulas are derived for the calculation of these important characteristics from a relatively general surface contour deformation.

  5. Evaluation on the Quality of Bangkok Tap Water with Other Drinking Purpose Water

    Science.gov (United States)

    Kordach, A.; Chardwattananon, C.; Wongin, K.; Chayaput, B.; Wongpat, N.

    2018-02-01

    The concern of drinking purposed water quality in Bangkok, Nonthaburi, and Samutprakarn provinces has been a problem for over fifteen years. Metropolitan Water Works Authority (MWA) of Thailand is fully responsible for providing water supply to the mentioned areas. The objective of Drinkable Tap Water Project is to make people realize in quality of tap water. Communities, school, government agencies, hotels, hospitals, department stores, and other organizations are participating in this project. MWA have collected at least 3 samples of water from the corresponding places and the samples have to meet the World Health Organization (WHO) guidelines level. This study is to evaluate water quality of tap water, storage water, filtered water, and filtered water dispenser. The water samples from 2,354 attending places are collected and analyzed. From October 2011 to September 2016, MWA analyzed 32,711 samples. The analyzed water parameters are free residual chlorine, appearance color, turbidity, pH, conductivity, total dissolved solids (TDS), and pathogenic bacteria; E.coli. The results indicated that a number of tap water samples had the highest number compliance with WHO guidelines levels at 98.40%. The filtered water, filtered water dispenser, and storage water were received 96.71%, 95.63%, and 90.88%, respectively. However, the several samples fail to pass WHO guideline level because they were contaminated by E.coli. The result is that tap water has the highest score among other sources probably because tap water has chlorine for disinfection and always is monitored by professional team round-the-clock services compared to the other water sources with less maintenance or cleaning. Also, water quality reports are continuously sent to customers by mail addresses. Tap water quality data are shown on MWA websites and Facebook. All these steps of work should enhance the confidence of tap water quality.

  6. Photonic-Enabled RF Canceller with Tunable Time-Delay Taps

    Science.gov (United States)

    2016-12-05

    Photonic -Enabled RF Canceller with Tunable Time-Delay Taps Kenneth E. Kolodziej, Sivasubramaniam Yegnanarayanan, Bradley T. Perry MIT Lincoln...canceller design that uses photonics and a vector modulator architecture to provide a high number of canceller taps with tunable time-delays, which allow...microwave photonics , RF cancellation. I. INTRODUCTION In-Band Full-Duplex (IBFD) technologies are being consid- ered for 5th generation (5G) wireless

  7. TAPRegExt: a VOResource Schema Extension for Describing TAP Services Version 1.0

    Science.gov (United States)

    Demleitner, Markus; Dowler, Patrick; Plante, Ray; Rixon, Guy; Taylor, Mark; Demleitner, Markus

    2012-08-01

    This document describes an XML encoding standard for metadata about services implementing the table access protocol TAP [TAP], referred to as TAPRegExt. Instance documents are part of the service's registry record or can be obtained from the service itself. They deliver information to both humans and software on the languages, output formats, and upload methods supported by the service, as well as data models implemented by the exposed tables, optional language features, and certain limits enforced by the service.

  8. Evaluation on the Quality of Bangkok Tap Water with Other Drinking Purpose Water

    Directory of Open Access Journals (Sweden)

    Kordach A.

    2018-01-01

    Full Text Available The concern of drinking purposed water quality in Bangkok, Nonthaburi, and Samutprakarn provinces has been a problem for over fifteen years. Metropolitan Water Works Authority (MWA of Thailand is fully responsible for providing water supply to the mentioned areas. The objective of Drinkable Tap Water Project is to make people realize in quality of tap water. Communities, school, government agencies, hotels, hospitals, department stores, and other organizations are participating in this project. MWA have collected at least 3 samples of water from the corresponding places and the samples have to meet the World Health Organization (WHO guidelines level. This study is to evaluate water quality of tap water, storage water, filtered water, and filtered water dispenser. The water samples from 2,354 attending places are collected and analyzed. From October 2011 to September 2016, MWA analyzed 32,711 samples. The analyzed water parameters are free residual chlorine, appearance color, turbidity, pH, conductivity, total dissolved solids (TDS, and pathogenic bacteria; E.coli. The results indicated that a number of tap water samples had the highest number compliance with WHO guidelines levels at 98.40%. The filtered water, filtered water dispenser, and storage water were received 96.71%, 95.63%, and 90.88%, respectively. However, the several samples fail to pass WHO guideline level because they were contaminated by E.coli. The result is that tap water has the highest score among other sources probably because tap water has chlorine for disinfection and always is monitored by professional team round-the-clock services compared to the other water sources with less maintenance or cleaning. Also, water quality reports are continuously sent to customers by mail addresses. Tap water quality data are shown on MWA websites and Facebook. All these steps of work should enhance the confidence of tap water quality.

  9. Efficient multichannel acoustic echo cancellation using constrained tap selection schemes in the subband domain

    Science.gov (United States)

    Desiraju, Naveen Kumar; Doclo, Simon; Wolff, Tobias

    2017-12-01

    Acoustic echo cancellation (AEC) is a key speech enhancement technology in speech communication and voice-enabled devices. AEC systems employ adaptive filters to estimate the acoustic echo paths between the loudspeakers and the microphone(s). In applications involving surround sound, the computational complexity of an AEC system may become demanding due to the multiple loudspeaker channels and the necessity of using long filters in reverberant environments. In order to reduce the computational complexity, the approach of partially updating the AEC filters is considered in this paper. In particular, we investigate tap selection schemes which exploit the sparsity present in the loudspeaker channels for partially updating subband AEC filters. The potential for exploiting signal sparsity across three dimensions, namely time, frequency, and channels, is analyzed. A thorough analysis of different state-of-the-art tap selection schemes is performed and insights about their limitations are gained. A novel tap selection scheme is proposed which overcomes these limitations by exploiting signal sparsity while not ignoring any filters for update in the different subbands and channels. Extensive simulation results using both artificial as well as real-world multichannel signals show that the proposed tap selection scheme outperforms state-of-the-art tap selection schemes in terms of echo cancellation performance. In addition, it yields almost identical echo cancellation performance as compared to updating all filter taps at a significantly reduced computational cost.

  10. Short Communication. Resin tapping activity as a contribution to the management of maritime pine forest

    Energy Technology Data Exchange (ETDEWEB)

    Palma, A.; Pereira, J.M.; Soares, P.

    2016-07-01

    Aim of the study: In this work potential resin yield in a region of high forest ability where maritime pine is the main species was estimated in order to understand the viability of promoting resin exploitation. Area of study: This study was conducted in Castro Da ire County in central region of Portugal. Material and methods: To quantify the resin yield of trees tapped for the first time two plots were installed in a maritime pine stand with average tree age 65 years. Before the beginning of the resin tapping, dendrometric tree variables were measured. Also, in a neighbouring stand, 25 trees were selected to check the relation between tree dbh and resin yield. Gum resin from every tree was weighted during the season. Estimates of potential resin yield in Castro Daire County were made based on data from National Forest Inventory plots, resin tapping legislation and resin yield values obtained in the field. Two scenarios were considered: high and low resin yield. To understand the intentions of forest owners towards restarting resin tapping activity 16 maritime pine forest owners were interviewed. Main results: The results point out a high yield potential capacity for gum resin production in the County: values between 2,025 and 5,873 tons were obtained. Research highlights: Results may highlight the important socio-economical role of the resin tapping activity and can be used to support national forest policies to the resin sector and give forest owners motivation to reactivate resin tapping activity. (Author)

  11. Modality-dependent effect of motion information in sensory-motor synchronised tapping.

    Science.gov (United States)

    Ono, Kentaro

    2018-05-14

    Synchronised action is important for everyday life. Generally, the auditory domain is more sensitive for coding temporal information, and previous studies have shown that auditory-motor synchronisation is much more precise than visuo-motor synchronisation. Interestingly, adding motion information improves synchronisation with visual stimuli and the advantage of the auditory modality seems to diminish. However, whether adding motion information also improves auditory-motor synchronisation remains unknown. This study compared tapping accuracy with a stationary or moving stimulus in both auditory and visual modalities. Participants were instructed to tap in synchrony with the onset of a sound or flash in the stationary condition, while these stimuli were perceived as moving from side to side in the motion condition. The results demonstrated that synchronised tapping with a moving visual stimulus was significantly more accurate than tapping with a stationary visual stimulus, as previous studies have shown. However, tapping with a moving auditory stimulus was significantly poorer than tapping with a stationary auditory stimulus. Although motion information impaired audio-motor synchronisation, an advantage of auditory modality compared to visual modality still existed. These findings are likely the result of higher temporal resolution in the auditory domain, which is likely due to the physiological and structural differences in the auditory and visual pathways in the brain. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. The Effect of Delayed Visual Feedback on Synchrony Perception in a Tapping Task

    Directory of Open Access Journals (Sweden)

    Mirjam Keetels

    2011-10-01

    Full Text Available Sensory events following a motor action are, within limits, interpreted as a causal consequence of those actions. For example, the clapping of the hands is initiated by the motor system, but subsequently visual, auditory, and tactile information is provided and processed. In the present study we examine the effect of temporal disturbances in this chain of motor-sensory events. Participants are instructed to tap a surface with their finger in synchrony with a chain of 20 sound clicks (ISI 750 ms. We examined the effect of additional visual information on this ‘tap-sound’-synchronization task. During tapping, subjects will see a video of their own tapping hand on a screen in front of them. The video can either be in synchrony with the tap (real-time recording, or can be slightly delayed (∼40–160 ms. In a control condition, no video is provided. We explore whether ‘tap-sound’ synchrony will be shifted as a function of the delayed visual feedback. Results will provide fundamental insights into how the brain preserves a causal interpretation of motor actions and their sensory consequences.

  13. A comparison of damage profiling of automated tap testers on aircraft CFRP panel

    Science.gov (United States)

    Mohd Aris, K. D.; Shariff, M. F.; Abd Latif, B. R.; Mohd Haris, M. Y.; Baidzawi, I. J.

    2017-12-01

    The use of composite materials nevertheless is getting more prominent. The combination of reinforcing fibers and matrices will produce the desired strength orientation, tailorability and not to mention the complex shape that is hard to form on metallic structure. The weight percentage of composite materials used in aerospace, civil, marine etc. has increased tremendously. Since composite are stacked together, the possibility of delamination and/disbond defects are highly present either in the monolithic or sandwich structures. Tap test is the cheapest form of nondestructive test to identify the presence of this damage. However, its inconsistency and wide area of coverage can reduce its effectivity since it is carried out manually. The indigenous automated tap tester known as KETOK was used to detect the damage due to trapped voids and air pockets. The mechanism of detection is through controlling the tapping on the surface automatically at a constant rate. Another manual tap tester RD-3 from Wichitech Industries Inc. was used as reference. The acquired data was translated into damage profiling and both results were compared. The results have shown that the indigenous automated tester can profile the damage better when compared with the existing tap tester. As a conclusion, the indigenous automated tap tester has a potential to be used as an IN-SITU damage detection tool to detect delamination and disbond damage on composite panel. However, more conclusive tests need to be done in order to make the unit available to conventional users.

  14. MINERAL WATER FROM SUPERMARKET VS. TAP WATER. SOME CONSIDERATIONS RELATED TO INNOCUITY

    Directory of Open Access Journals (Sweden)

    Ciprian – Nicolae POPA

    2015-04-01

    Full Text Available 15 Romanian brands of mineral water were purchased from hypermarket. For each of the 15 mineral waters were determined the content of nitrates, nitrites and pH. The data obtained were compared with the content of nitrates, nitrites and pH of the tap water collected in 15 locations in Bucharest, according to data released by the Apa Nova operator. The results showed that the mean of tap water pH in Bucharest, although slightly higher than the tested mineral waters pH, did not differ significantly from the mean of mineral waters pH, being situated in the alkaline domain. The mean content of nitrates in tap water in Bucharest, did not differ significantly from that of the tested mineral waters (t = 0.811. Nitrates content of tap water in Bucharest was significantly distinct less, as the pH was higher (r = 0.68**. Basically, the change in pH by one unit, lowers the amount of nitrate by 46%. Bucharest tap water nitrites content was significantly lower than that of tested mineral waters (0.005 mg/l to 0.0124; t = 2.674*. Basically, Bucharest tap water contained up to 2.5 times less nitrites than the nitrites mean of tested mineral waters.

  15. Pengaruh Self Tapping terhadap Penurunan Level Dysmenorhea pada Mahasiswi Program Studi Ilmu Keperawatan

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    Wiwin Lismidiati

    2017-10-01

    Full Text Available Dysmenorrhea primer adalah nyeri pada perut bagian bawah yang dirasakan pada saat menstruasi tanpa adanya kelainan pada panggul. Banyaknya gejala yang muncul saat dysmenorrhea dapat berpengaruh pada aktivitas kerja dan aktivitas sehari-hari. Ada beberapa manajemen nyeri untuk mengatasi dysmenorrhea primer, salah satunya adalah dengan self tapping. Tujuan penelitian untuk menganalisis efektifitas terapi self tapping dalam menurunkan level nyeri dysmenorrhea primer pada mahasiswi PSIK FK UGM. Penelitian ini adalah jenis penelitian quasi experiment non randomized pretest-postest with control. Pada kelompok intervensi diberikan perlakuan self tapping, sedangkan pada kelompok kontrol diberikan perlakuan nafas dalam. Pengukuran level nyeri dysmenorrhea primer dilakukan menggunakan instrumen Numerical Rating Scale (NRS dengan skala 1−10. Jumlah responden sebanyak 60 orang. Untuk mengetahui perbandingan level nyeri sebelum dan sesudah terapi pada kelompok intervensi dan kelompok kontrol, dilakukan uji statistik Wilcoxon. Sedangkan untuk membandingkan perbedaan level nyeri antara kelompok intervensi dan kelompok kontrol dilakukan uji statistik Mann Whitney. Hasil menunjukkan intervensi self tapping lebih efektif menurunkan level nyeri dysmenorrhea primer pada mahasiswi PSIK FK UGM dengan nilai p = 0,007. Kesimpulannya terdapat pengaruh terapi self tapping terhadap terhadap level nyeri dysmenorrhea primer pada mahasiswi PSIK FK UGM. Terapi self tapping dapat dijadikan pilihan penanganan untuk mengurangi nyeri pada saat mengalami dysmenorrhea primer.

  16. Tapped density optimisation for four agricultural wastes - Part II: Performance analysis and Taguchi-Pareto

    Directory of Open Access Journals (Sweden)

    Ajibade Oluwaseyi Ayodele

    2016-01-01

    Full Text Available In this attempt, which is a second part of discussions on tapped density optimisation for four agricultural wastes (particles of coconut, periwinkle, palm kernel and egg shells, performance analysis for comparative basis is made. This paper pioneers a study direction in which optimisation of process variables are pursued using Taguchi method integrated with the Pareto 80-20 rule. Negative percentage improvements resulted when the optimal tapped density was compared with the average tapped density. However, the performance analysis between optimal tapped density and the peak tapped density values yielded positive percentage improvements for the four filler particles. The performance analysis results validate the effectiveness of using the Taguchi method in improving the tapped density properties of the filler particles. The application of the Pareto 80-20 rule to the table of parameters and levels produced revised tables of parameters and levels which helped to identify the factor-levels position of each parameter that is economical to optimality. The Pareto 80-20 rule also produced revised S/N response tables which were used to know the relevant S/N ratios that are relevant to optimality.

  17. Biological mechanisms associated with triazophos (TAP) removal by horizontal subsurface flow constructed wetlands (HSFCW)

    International Nuclear Information System (INIS)

    Wu, Juan; Feng, Yuqin; Dai, Yanran; Cui, Naxin; Anderson, Bruce; Cheng, Shuiping

    2016-01-01

    Triazophos (TAP) is a widely used pesticide that is easily accumulated in the environment due to its relatively high stability: this accumulation from agricultural runoff results in potential hazards to aquatic ecosystems. Constructed wetlands are generally considered to be an effective technology for treating TAP polluted surface water. However, knowledge about the biological mechanisms of TAP removal is still lacking. This study investigates the responses of a wetland plant (Canna indica), substrate enzymes and microbial communities in bench-scale horizontal subsurface-flow constructed wetlands (HSCWs) loaded with different TAP concentrations (0, 0.1, 0.5 and 5 mg·L"−"1). The results indicate that TAP stimulated the activities of superoxide dismutase (SOD) and peroxidase (POD) in the roots of C. indica. The highest TAP concentrations significantly inhibited photosynthetic activities, as shown by a reduced effective quantum yield of PS II (Φ_P_S_I_I) and lower electron transport rates (ETR). However, interestingly, the lower TAP loadings exhibited some favorable effects on these two variables, suggesting that C. indica is a suitable species for use in wetlands designed for treatment of low TAP concentrations. Urease and alkaline phosphatase (ALP) in the wetland substrate were activated by TAP. Two-way ANOVA demonstrated that urease activity was influenced by both the TAP concentrations and season, while acidphosphatase (ACP) only responded to seasonal variations. Analysis of high throughput sequencing of 16S rRNA revealed seasonal variations in the microbial community structure of the wetland substrate at the phylum and family levels. In addition, urease activity had a greater correlation with the relative abundance of some functional microbial groups, such as the Bacillaceae family, and the ALP and ACP may be influenced by the plant more than substrate microbial communities. - Highlights: • Physiological responses of the wetland plant to triazophos loads

  18. A computer vision framework for finger-tapping evaluation in Parkinson's disease.

    Science.gov (United States)

    Khan, Taha; Nyholm, Dag; Westin, Jerker; Dougherty, Mark

    2014-01-01

    The rapid finger-tapping test (RFT) is an important method for clinical evaluation of movement disorders, including Parkinson's disease (PD). In clinical practice, the naked-eye evaluation of RFT results in a coarse judgment of symptom scores. We introduce a novel computer-vision (CV) method for quantification of tapping symptoms through motion analysis of index-fingers. The method is unique as it utilizes facial features to calibrate tapping amplitude for normalization of distance variation between the camera and subject. The study involved 387 video footages of RFT recorded from 13 patients diagnosed with advanced PD. Tapping performance in these videos was rated by two clinicians between the symptom severity levels ('0: normal' to '3: severe') using the unified Parkinson's disease rating scale motor examination of finger-tapping (UPDRS-FT). Another set of recordings in this study consisted of 84 videos of RFT recorded from 6 healthy controls. These videos were processed by a CV algorithm that tracks the index-finger motion between the video-frames to produce a tapping time-series. Different features were computed from this time series to estimate speed, amplitude, rhythm and fatigue in tapping. The features were trained in a support vector machine (1) to categorize the patient group between UPDRS-FT symptom severity levels, and (2) to discriminate between PD patients and healthy controls. A new representative feature of tapping rhythm, 'cross-correlation between the normalized peaks' showed strong Guttman correlation (μ2=-0.80) with the clinical ratings. The classification of tapping features using the support vector machine classifier and 10-fold cross validation categorized the patient samples between UPDRS-FT levels with an accuracy of 88%. The same classification scheme discriminated between RFT samples of healthy controls and PD patients with an accuracy of 95%. The work supports the feasibility of the approach, which is presumed suitable for PD monitoring

  19. Biological mechanisms associated with triazophos (TAP) removal by horizontal subsurface flow constructed wetlands (HSFCW)

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Juan; Feng, Yuqin; Dai, Yanran; Cui, Naxin [State Key Laboratory of Pollution Control and ResourceReuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092 (China); Anderson, Bruce [Department of Civil Engineering, Queen' s University, Kingston K7L3N6 (Canada); Cheng, Shuiping, E-mail: shpcheng@tongji.edu.cn [State Key Laboratory of Pollution Control and ResourceReuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092 (China)

    2016-05-15

    Triazophos (TAP) is a widely used pesticide that is easily accumulated in the environment due to its relatively high stability: this accumulation from agricultural runoff results in potential hazards to aquatic ecosystems. Constructed wetlands are generally considered to be an effective technology for treating TAP polluted surface water. However, knowledge about the biological mechanisms of TAP removal is still lacking. This study investigates the responses of a wetland plant (Canna indica), substrate enzymes and microbial communities in bench-scale horizontal subsurface-flow constructed wetlands (HSCWs) loaded with different TAP concentrations (0, 0.1, 0.5 and 5 mg·L{sup −1}). The results indicate that TAP stimulated the activities of superoxide dismutase (SOD) and peroxidase (POD) in the roots of C. indica. The highest TAP concentrations significantly inhibited photosynthetic activities, as shown by a reduced effective quantum yield of PS II (Φ{sub PSII}) and lower electron transport rates (ETR). However, interestingly, the lower TAP loadings exhibited some favorable effects on these two variables, suggesting that C. indica is a suitable species for use in wetlands designed for treatment of low TAP concentrations. Urease and alkaline phosphatase (ALP) in the wetland substrate were activated by TAP. Two-way ANOVA demonstrated that urease activity was influenced by both the TAP concentrations and season, while acidphosphatase (ACP) only responded to seasonal variations. Analysis of high throughput sequencing of 16S rRNA revealed seasonal variations in the microbial community structure of the wetland substrate at the phylum and family levels. In addition, urease activity had a greater correlation with the relative abundance of some functional microbial groups, such as the Bacillaceae family, and the ALP and ACP may be influenced by the plant more than substrate microbial communities. - Highlights: • Physiological responses of the wetland plant to triazophos

  20. Self-tapping ability of carbon fibre reinforced polyetheretherketone suture anchors.

    Science.gov (United States)

    Feerick, Emer M; Wilson, Joanne; Jarman-Smith, Marcus; Ó'Brádaigh, Conchur M; McGarry, J Patrick

    2014-10-01

    An experimental and computational investigation of the self-tapping ability of carbon fibre reinforced polyetheretherketone (CFR-PEEK) has been conducted. Six CFR-PEEK suture anchor designs were investigated using PEEK-OPTIMA® Reinforced, a medical grade of CFR-PEEK. Experimental tests were conducted to investigate the maximum axial force and torque required for self-taping insertion of each anchor design. Additional experimental tests were conducted for some anchor designs using pilot holes. Computational simulations were conducted to determine the maximum stress in each anchor design at various stages of insertion. Simulations also were performed to investigate the effect of wall thickness in the anchor head. The maximum axial force required to insert a self-tapping CFR-PEEK suture anchor did not exceed 150 N for any anchor design. The maximum torque required to insert a self-tapping CFR-PEEK suture anchor did not exceed 0.8 Nm. Computational simulations reveal significant stress concentrations in the region of the anchor tip, demonstrating that a re-design of the tip geometry should be performed to avoid fracture during self-tapping, as observed in the experimental component of this study. This study demonstrates the ability of PEEK-OPTIMA Reinforced suture anchors to self-tap polyurethane foam bone analogue. This provides motivation to further investigate the self-tapping ability of CFR-PEEK suture anchors in animal/cadaveric bone. An optimised design for CFR-PEEK suture anchors offers the advantages of radiolucency, and mechanical properties similar to bone with the ability to self-tap. This may have positive implications for reducing surgery times and the associated costs with the procedure. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  1. Cross-cultural influences on rhythm processing: reproduction, discrimination, and beat tapping.

    Science.gov (United States)

    Cameron, Daniel J; Bentley, Jocelyn; Grahn, Jessica A

    2015-01-01

    The structures of musical rhythm differ between cultures, despite the fact that the ability to entrain movement to musical rhythm occurs in virtually all individuals across cultures. To measure the influence of culture on rhythm processing, we tested East African and North American adults on perception, production, and beat tapping for rhythms derived from East African and Western music. To assess rhythm perception, participants identified whether pairs of rhythms were the same or different. To assess rhythm production, participants reproduced rhythms after hearing them. To assess beat tapping, participants tapped the beat along with repeated rhythms. We expected that performance in all three tasks would be influenced by the culture of the participant and the culture of the rhythm. Specifically, we predicted that a participant's ability to discriminate, reproduce, and accurately tap the beat would be better for rhythms from their own culture than for rhythms from another culture. In the rhythm discrimination task, there were no differences in discriminating culturally familiar and unfamiliar rhythms. In the rhythm reproduction task, both groups reproduced East African rhythms more accurately than Western rhythms, but East African participants also showed an effect of cultural familiarity, leading to a significant interaction. In the beat tapping task, participants in both groups tapped the beat more accurately for culturally familiar than for unfamiliar rhythms. Moreover, there were differences between the two participant groups, and between the two types of rhythms, in the metrical level selected for beat tapping. The results demonstrate that culture does influence the processing of musical rhythm. In terms of the function of musical rhythm, our results are consistent with theories that musical rhythm enables synchronization. Musical rhythm may foster musical cultural identity by enabling within-group synchronization to music, perhaps supporting social cohesion.

  2. Timing at peak force may be the hidden target controlled in continuation and synchronization tapping.

    Science.gov (United States)

    Du, Yue; Clark, Jane E; Whitall, Jill

    2017-05-01

    Timing control, such as producing movements at a given rate or synchronizing movements to an external event, has been studied through a finger-tapping task where timing is measured at the initial contact between finger and tapping surface or the point when a key is pressed. However, the point of peak force is after the time registered at the tapping surface and thus is a less obvious but still an important event during finger tapping. Here, we compared the time at initial contact with the time at peak force as participants tapped their finger on a force sensor at a given rate after the metronome was turned off (continuation task) or in synchrony with the metronome (sensorimotor synchronization task). We found that, in the continuation task, timing was comparably accurate between initial contact and peak force. These two timing events also exhibited similar trial-by-trial statistical dependence (i.e., lag-one autocorrelation). However, the central clock variability was lower at the peak force than the initial contact. In the synchronization task, timing control at peak force appeared to be less variable and more accurate than that at initial contact. In addition to lower central clock variability, the mean SE magnitude at peak force (SEP) was around zero while SE at initial contact (SEC) was negative. Although SEC and SEP demonstrated the same trial-by-trial statistical dependence, we found that participants adjusted the time of tapping to correct SEP, but not SEC, toward zero. These results suggest that timing at peak force is a meaningful target of timing control, particularly in synchronization tapping. This result may explain the fact that SE at initial contact is typically negative as widely observed in the preexisting literature.

  3. The 3-Second Rule in Hereditary Pure Cerebellar Ataxia: A Synchronized Tapping Study

    Science.gov (United States)

    Matsuda, Shunichi; Matsumoto, Hideyuki; Furubayashi, Toshiaki; Hanajima, Ritsuko; Tsuji, Shoji; Ugawa, Yoshikazu; Terao, Yasuo

    2015-01-01

    The ‘3-second rule’ has been proposed based on miscellaneous observations that a time period of around 3 seconds constitutes the fundamental unit of time related to the neuro-cognitive machinery in normal humans. The aim of paper was to investigate the temporal processing in patients with spinocerebellar ataxia type 6 (SCA6) and SCA31, pure cerebellar types of spinocerebellar degeneration, using a synchronized tapping task. Seventeen SCA patients (11 SCA6, 6 SCA31) and 17 normal age-matched volunteers participated. The task required subjects to tap a keyboard in synchrony with sequences of auditory stimuli presented at fixed interstimulus intervals (ISIs) between 200 and 4800 ms. In this task, the subjects required non-motor components to estimate the time of forthcoming tone in addition to motor components to tap. Normal subjects synchronized their taps to the presented tones at shorter ISIs, whereas as the ISI became longer, the normal subjects displayed greater latency between the tone and the tapping (transition zone). After the transition zone, normal subjects pressed the button delayed relative to the tone. On the other hand, SCA patients could not synchronize their tapping with the tone even at shorter ISIs, although they pressed the button delayed relative to the tone earlier than normal subjects did. The earliest time of delayed tapping appearance after the transition zone was 4800 ms in normal subjects but 1800 ms in SCA patients. The span of temporal integration in SCA patients is shortened compared to that in normal subjects. This could represent non-motor cerebellar dysfunction in SCA patients. PMID:25706752

  4. Delayed finger tapping and cognitive responses in preterm-born male teenagers with mild spastic diplegia.

    Science.gov (United States)

    Gao, Fei; Mei, Xi; Chen, Andrew C N

    2015-02-01

    Information on fine motor and basic cognitive functions in spastic diplegia is sparse in the literature. The aim of this study was to investigate index finger's tapping speed and cognitive functions in categorization and old/new recognition of pictures in patients with mild spastic diplegia. Fifteen preterm-born male teenagers with mild spastic diplegia and 15 healthy male teenagers participated in this study. Finger-tapping tests and cognitive tests were performed on all participants. Outcomes were compared between the two groups. In the finger-tapping tests, the tapping speed was significantly slower in patients than in controls. In the tests of tapping one key persistently and tapping two keys alternately, the reaction time gaps between the left and right digits were larger in patients than in controls. In the categorization tests, the accuracies and reaction times for animal/plant and girl face pictures, but not for boy face pictures, were significantly worse in patients than in controls. In the recognition tests, the accuracies for old/new, animal/plant, and boy/girl face pictures were significantly lower in patients than in controls. The reaction times for old/new, animal/plant, and new face pictures, but not for old face pictures, were significantly longer in patients compared with controls. Our results demonstrate delayed finger tapping and cognitive responses in preterm-born male teenagers with mild spastic diplegia. Our experimental paradigm is sensitive for the study of fine motor and cognitive functions between patients and healthy controls. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Automatic and Objective Assessment of Alternating Tapping Performance in Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Mevludin Memedi

    2013-12-01

    Full Text Available This paper presents the development and evaluation of a method for enabling quantitative and automatic scoring of alternating tapping performance of patients with Parkinson’s disease (PD. Ten healthy elderly subjects and 95 patients in different clinical stages of PD have utilized a touch-pad handheld computer to perform alternate tapping tests in their home environments. First, a neurologist used a web-based system to visually assess impairments in four tapping dimensions (‘speed’, ‘accuracy’, ‘fatigue’ and ‘arrhythmia’ and a global tapping severity (GTS. Second, tapping signals were processed with time series analysis and statistical methods to derive 24 quantitative parameters. Third, principal component analysis was used to reduce the dimensions of these parameters and to obtain scores for the four dimensions. Finally, a logistic regression classifier was trained using a 10-fold stratified cross-validation to map the reduced parameters to the corresponding visually assessed GTS scores. Results showed that the computed scores correlated well to visually assessed scores and were significantly different across Unified Parkinson’s Disease Rating Scale scores of upper limb motor performance. In addition, they had good internal consistency, had good ability to discriminate between healthy elderly and patients in different disease stages, had good sensitivity to treatment interventions and could reflect the natural disease progression over time. In conclusion, the automatic method can be useful to objectively assess the tapping performance of PD patients and can be included in telemedicine tools for remote monitoring of tapping.

  6. Inorganic chemical quality of European tap-water: 2. Geographical distribution

    International Nuclear Information System (INIS)

    Flem, B.; Reimann, C.; Birke, M.; Banks, D.; Filzmoser, P.; Frengstad, B.

    2015-01-01

    Highlights: • European scale comparison of tap water. • 579 tap water samples have been analyses for more than 60 parameters. • Chemical geographical distribution. • Water treatment processes. • Importance of geology on tap water quality. - Abstract: 579 tap water samples were collected at the European scale and analysed at a single laboratory for more than 60 parameters. This dataset is analysed here in terms of the spatial and national distribution of the analysed inorganic chemical parameters. The distribution of most parameters is controlled by various artificial and natural factors (land use, distribution network, water source and treatment, geographical location and geology). The distribution of nitrate can be interpreted in terms of land use and climate. Water treatment affects the distribution of phosphorus in tap water; especially the policy of adding phosphate to potable water in the UK to suppress plumbosolvency. The distribution of alkalinity, Ca, Mg, Sr and Li appears to reflect both water source (low in surface waters) and the geological contrast between base-poor crystalline rock terrains and carbonate rich sedimentary rock. The Scandinavian nations’ tap water shows the highest concentrations of most of the rare earth elements, probably reflecting their geological availability and mobility in low pH raw water sources. The distribution of fluoride, uranium and arsenic also appear to exhibit geological and source (groundwater versus surface water) controls. Hungary returns several high As results, which may reflect As-rich reducing groundwaters of the Pannonian basin. Much Estonian tap water reflects a very specific hydrochemical environment, namely Palaeozoic near-coastal aquifers, which yield deep, reducing or saline groundwater (possibly influenced by marine intrusion), enriched in Ba, B, Br − , Cl − , Eu, F − , I, Li, K, Mn and Na

  7. Cerebrospinal Fluid Lumbar Tapping Utilization for Suspected Ventriculoperitoneal Shunt Under-Drainage Malfunctions.

    Science.gov (United States)

    Lee, Jong-Beom; Ahn, Ho-Young; Lee, Hong-Jae; Yang, Ji-Ho; Yi, Jin-Seok; Lee, Il-Woo

    2017-01-01

    The diagnosis of shunt malfunction can be challenging since neuroimaging results are not always correlated with clinical outcomes. The purpose of this study was to evaluate the efficacy of a simple, minimally invasive cerebrospinal fluid (CSF) lumbar tapping test that predicts shunt under-drainage in hydrocephalus patients. We retrospectively reviewed the clinical and radiological features of 48 patients who underwent routine CSF lumbar tapping after ventriculoperitoneal shunt (VPS) operation using a programmable shunting device. We compared shunt valve opening pressure and CSF lumbar tapping pressure to check under-drainage. The mean pressure difference between valve opening pressure and CSF lumbar tapping pressure of all patients were 2.21±24.57 mmH 2 O. The frequency of CSF lumbar tapping was 2.06±1.26 times. Eighty five times lumbar tapping of 41 patients showed that their VPS function was normal which was consistent with clinical improvement and decreased ventricle size on computed tomography scan. The mean pressure difference in these patients was -3.69±19.20 mmH 2 O. The mean frequency of CSF lumbar tapping was 2.07±1.25 times. Fourteen cases of 10 patients revealed suspected VPS malfunction which were consistent with radiological results and clinical symptoms, defined as changes in ventricle size and no clinical improvement. The mean pressure difference was 38.07±23.58 mmH 2 O. The mean frequency of CSF lumbar tapping was 1.44±1.01 times. Pressure difference greater than 35 mmH 2 O was shown in 2.35% of the normal VPS function group (2 of 85) whereas it was shown in 64.29% of the suspected VPS malfunction group (9 of 14). The difference was statistically significant ( p =0.000001). Among 10 patients with under-drainage, 5 patients underwent shunt revision. The causes of the shunt malfunction included 3 cases of proximal occlusion and 2 cases of distal obstruction and valve malfunction. Under-drainage of CSF should be suspected if CSF lumbar tapping

  8. Functional Imaging of Human Vestibular Cortex Activity Elicited by Skull Tap and Auditory Tone Burst

    Science.gov (United States)

    Noohi, Fatemeh; Kinnaird, Catherine; Wood, Scott; Bloomberg, Jacob; Mulavara, Ajitkumar; Seidler, Rachael

    2014-01-01

    The aim of the current study was to characterize the brain activation in response to two modes of vestibular stimulation: skull tap and auditory tone burst. The auditory tone burst has been used in previous studies to elicit saccular Vestibular Evoked Myogenic Potentials (VEMP) (Colebatch & Halmagyi 1992; Colebatch et al. 1994). Some researchers have reported that airconducted skull tap elicits both saccular and utricle VEMPs, while being faster and less irritating for the subjects (Curthoys et al. 2009, Wackym et al., 2012). However, it is not clear whether the skull tap and auditory tone burst elicit the same pattern of cortical activity. Both forms of stimulation target the otolith response, which provides a measurement of vestibular function independent from semicircular canals. This is of high importance for studying the vestibular disorders related to otolith deficits. Previous imaging studies have documented activity in the anterior and posterior insula, superior temporal gyrus, inferior parietal lobule, pre and post central gyri, inferior frontal gyrus, and the anterior cingulate cortex in response to different modes of vestibular stimulation (Bottini et al., 1994; Dieterich et al., 2003; Emri et al., 2003; Schlindwein et al., 2008; Janzen et al., 2008). Here we hypothesized that the skull tap elicits the similar pattern of cortical activity as the auditory tone burst. Subjects put on a set of MR compatible skull tappers and headphones inside the 3T GE scanner, while lying in supine position, with eyes closed. All subjects received both forms of the stimulation, however, the order of stimulation with auditory tone burst and air-conducted skull tap was counterbalanced across subjects. Pneumatically powered skull tappers were placed bilaterally on the cheekbones. The vibration of the cheekbone was transmitted to the vestibular cortex, resulting in vestibular response (Halmagyi et al., 1995). Auditory tone bursts were also delivered for comparison. To validate

  9. Functional magnetic resonance imaging study comparing rhythmic finger tapping in children and adults.

    Science.gov (United States)

    De Guio, François; Jacobson, Sandra W; Molteno, Christopher D; Jacobson, Joseph L; Meintjes, Ernesta M

    2012-02-01

    This study compared brain activation during unpaced rhythmic finger tapping in 12-year-old children with that of adults. Subjects pressed a button at a pace initially indicated by a metronome (12 consecutive tones), and then continued for 16 seconds of unpaced tapping to provide an assessment of their ability to maintain a steady rhythm. These analyses focused on the superior vermis of the cerebellum, which is known to play a key role in timing. Twelve adults and 12 children performed this rhythmic finger tapping task in a 3 T scanner. Whole-brain analyses were performed in Brain Voyager, with a random-effects analysis of variance using a general linear model. A dedicated cerebellar atlas was used to localize cerebellar activations. As in adults, unpaced rhythmic finger tapping in children demonstrated activations in the primary motor cortex, premotor cortex, and cerebellum. However, overall activation was different, in that adults demonstrated much more deactivation in response to the task, particularly in the occipital and frontal cortices. The other main differences involved the additional recruitment of motor and premotor areas in children compared with adults, and increased activity in the vermal region of the cerebellum. These findings suggest that the timing component of the unpaced rhythmic finger tapping task is less efficient and automatic in children, who need to recruit the superior vermis more intensively to maintain the rhythm, although they performed somewhat more poorly than adults. Copyright © 2012 Elsevier Inc. All rights reserved.

  10. Tapping mode imaging and measurements with an inverted atomic force microscope.

    Science.gov (United States)

    Chan, Sandra S F; Green, John-Bruce D

    2006-07-18

    This report demonstrates the successful use of the inverted atomic force microscope (i-AFM) for tapping mode AFM imaging of cantilever-supported samples. i-AFM is a mode of AFM operation in which a sample supported on a tipless cantilever is imaged by one of many tips in a microfabricated tip array. Tapping mode is an intermittent contact mode whereby the cantilever is oscillated at or near its resonance frequency, and the amplitude and/or phase are used to image the sample. In the process of demonstrating that tapping mode images could be obtained in the i-AFM design, it was observed that the amplitude of the cantilever oscillation decreased markedly as the cantilever and tip array were approached. The source of this damping of the cantilever oscillations was identified to be the well-known "squeeze film damping", and the extent of damping was a direct consequence of the relatively shorter tip heights for the tip arrays, as compared to those of commercially available tapping mode cantilevers with integrated tips. The functional form for the distance dependence of the damping coefficient is in excellent agreement with previously published models for squeeze film damping, and the values for the fitting parameters make physical sense. Although the severe damping reduces the cantilever free amplitude substantially, we found that we were still able to access the low-amplitude regime of oscillation necessary for attractive tapping mode imaging of fragile molecules.

  11. Idiopathic normal pressure hydrocephalus, quantitative EEG findings, and the cerebrospinal fluid tap test: a pilot study.

    Science.gov (United States)

    Seo, Jong-Geun; Kang, Kyunghun; Jung, Ji-Young; Park, Sung-Pa; Lee, Maan-Gee; Lee, Ho-Won

    2014-12-01

    In this pilot study, we analyzed relationships between quantitative EEG measurements and clinical parameters in idiopathic normal pressure hydrocephalus patients, along with differences in these quantitative EEG markers between cerebrospinal fluid tap test responders and nonresponders. Twenty-six idiopathic normal pressure hydrocephalus patients (9 cerebrospinal fluid tap test responders and 17 cerebrospinal fluid tap test nonresponders) constituted the final group for analysis. The resting EEG was recorded and relative powers were computed for seven frequency bands. Cerebrospinal fluid tap test nonresponders, when compared with responders, showed a statistically significant increase in alpha2 band power at the right frontal and centrotemporal regions. Higher delta2 band powers in the frontal, central, parietal, and occipital regions and lower alpha1 band powers in the right temporal region significantly correlated with poorer cognitive performance. Higher theta1 band powers in the left parietal and occipital regions significantly correlated with gait dysfunction. And higher delta1 band powers in the right frontal regions significantly correlated with urinary disturbance. Our findings may encourage further research using quantitative EEG in patients with ventriculomegaly as a potential electrophysiological marker for predicting cerebrospinal fluid tap test responders. This study additionally suggests that the delta, theta, and alpha bands are statistically correlated with the severity of symptoms in idiopathic normal pressure hydrocephalus patients.

  12. Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao

    International Nuclear Information System (INIS)

    Yiruhan; Wang Qiaojun; Mo Cehui; Li Yanwen; Gao Peng; Tai Yiping; Zhang Yan; Ruan Zhili; Xu Jiawei

    2010-01-01

    Four fluoroquinolone antibiotics (norfloxacin, ciprofloxacin, lomefloxacin, and enrofloxacin) in tap water in Guangzhou and Macao were analyzed using high performance liquid chromatography fluorescence detection. The results showed that all target antibiotics were detected in high rate both in Guangzhou (77.5%) and Macao (100%), ranging from 1.0 to 679.7 ng/L (SD ≤ 37.6) in Guangzhou, and from 2.0 to 37.0 ng/L (SD ≤ 2.5) in Macao. The fluoroquinolone antibiotics pollution in tap water widely distributes in Guangzhou and Macao. In addition, the effect of rainfall on concentration of fluoroquinolone antibiotics in south China was also investigated. Our result indicates that the antibiotic concentration in tap water in Guangzhou tends to obviously reduce at the beginning of rainy season, even decreases below the limit of quantification immediately. Thus, it was clarified that the heavy rain in south China has the function of reducing the fluoroquinolone antibiotics concentrations in tap water. - The antibiotics were detected in the tap water in Guangzhou and Macao using our developed method for fluoresence detection with high performance liquid chromatography

  13. Determination of four fluoroquinolone antibiotics in tap water in Guangzhou and Macao

    Energy Technology Data Exchange (ETDEWEB)

    Yiruhan; Wang Qiaojun [Department of Environmental Engineering, Jinan University, Huangpudadaoxi 601, Guangzhou 510632 (China); Mo Cehui, E-mail: tchmo@jnu.edu.c [Department of Environmental Engineering, Jinan University, Huangpudadaoxi 601, Guangzhou 510632 (China); Li Yanwen; Gao Peng; Tai Yiping; Zhang Yan; Ruan Zhili; Xu Jiawei [Department of Environmental Engineering, Jinan University, Huangpudadaoxi 601, Guangzhou 510632 (China)

    2010-07-15

    Four fluoroquinolone antibiotics (norfloxacin, ciprofloxacin, lomefloxacin, and enrofloxacin) in tap water in Guangzhou and Macao were analyzed using high performance liquid chromatography fluorescence detection. The results showed that all target antibiotics were detected in high rate both in Guangzhou (77.5%) and Macao (100%), ranging from 1.0 to 679.7 ng/L (SD {<=} 37.6) in Guangzhou, and from 2.0 to 37.0 ng/L (SD {<=} 2.5) in Macao. The fluoroquinolone antibiotics pollution in tap water widely distributes in Guangzhou and Macao. In addition, the effect of rainfall on concentration of fluoroquinolone antibiotics in south China was also investigated. Our result indicates that the antibiotic concentration in tap water in Guangzhou tends to obviously reduce at the beginning of rainy season, even decreases below the limit of quantification immediately. Thus, it was clarified that the heavy rain in south China has the function of reducing the fluoroquinolone antibiotics concentrations in tap water. - The antibiotics were detected in the tap water in Guangzhou and Macao using our developed method for fluoresence detection with high performance liquid chromatography

  14. Phosphate ions as inhibiting agents for copper corrosion in chlorinated tap water

    Energy Technology Data Exchange (ETDEWEB)

    Yohai, L. [División Electroquímica y Corrosión, INTEMA, CONICET, UNMdP, Juan B. Justo 4302, B7608FDQ Mar del Plata (Argentina); Schreiner, W.H. [Laboratório de Superfícies e Interfases, Departamento de Física, Universidade Federal do Paraná, 81531-990 Curitiba, PR (Brazil); Vázquez, M., E-mail: mvazquez@fi.mdp.edu.ar [División Electroquímica y Corrosión, INTEMA, CONICET, UNMdP, Juan B. Justo 4302, B7608FDQ Mar del Plata (Argentina); Valcarce, M.B. [División Electroquímica y Corrosión, INTEMA, CONICET, UNMdP, Juan B. Justo 4302, B7608FDQ Mar del Plata (Argentina)

    2013-05-15

    PO{sub 4}{sup 3−} ions as corrosion inhibitor were investigated on copper in tap water in the presence of NaClO. The inhibitor was evaluated by electrochemical techniques and weight loss tests. Raman spectroscopy and X-ray photoelectron spectroscopy were used to study the passive layer. In inhibited tap water, the passive layer is thick and compact if NaClO is present. Weight-loss tests showed the inhibition of uniform dissolution and no pitting attack. When adding NaClO, Cu{sub 3}(PO{sub 4}){sub 2} is incorporated to the passive film. Thus, phosphate ions are effective as inhibitors for copper in tap water, even when using high dosages of biocides. - Highlights: ► Changes in the copper corrosion after adding phosphate to tap water were analyzed. ► When NaClO and phosphates are present, Cu{sub 3}(PO{sub 4}){sub 2} participates of the surface film. ► In the absence of biocide the surface film contains a mixture of Cu{sub 2}O, CuO and Cu(OH){sub 2}. ► PO{sub 4}{sup 3−} is an effective inhibitor for Cu in tap water containing high NaClO dosages.

  15. Predictive rhythmic tapping to isochronous and tempo changing metronomes in the nonhuman primate.

    Science.gov (United States)

    Gámez, Jorge; Yc, Karyna; Ayala, Yaneri A; Dotov, Dobromir; Prado, Luis; Merchant, Hugo

    2018-04-30

    Beat entrainment is the ability to entrain one's movements to a perceived periodic stimulus, such as a metronome or a pulse in music. Humans have a capacity to predictively respond to a periodic pulse and to dynamically adjust their movement timing to match the varying music tempos. Previous studies have shown that monkeys share some of the human capabilities for rhythmic entrainment, such as tapping regularly at the period of isochronous stimuli. However, it is still unknown whether monkeys can predictively entrain to dynamic tempo changes like humans. To address this question, we trained monkeys in three tapping tasks and compared their rhythmic entrainment abilities with those of humans. We found that, when immediate feedback about the timing of each movement is provided, monkeys can predictively entrain to an isochronous beat, generating tapping movements in anticipation of the metronome pulse. This ability also generalized to a novel untrained tempo. Notably, macaques can modify their tapping tempo by predicting the beat changes of accelerating and decelerating visual metronomes in a manner similar to humans. Our findings support the notion that nonhuman primates share with humans the ability of temporal anticipation during tapping to isochronous and smoothly changing sequences of stimuli. © 2018 New York Academy of Sciences.

  16. Bi-harmonic cantilever design for improved measurement sensitivity in tapping-mode atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Loganathan, Muthukumaran; Bristow, Douglas A., E-mail: dbristow@mst.edu [Department of Mechanical and Aerospace Engineering, Missouri University of Science and Technology, Rolla, Missouri 65401 (United States)

    2014-04-15

    This paper presents a method and cantilever design for improving the mechanical measurement sensitivity in the atomic force microscopy (AFM) tapping mode. The method uses two harmonics in the drive signal to generate a bi-harmonic tapping trajectory. Mathematical analysis demonstrates that the wide-valley bi-harmonic tapping trajectory is as much as 70% more sensitive to changes in the sample topography than the standard single-harmonic trajectory typically used. Although standard AFM cantilevers can be driven in the bi-harmonic tapping trajectory, they require large forcing at the second harmonic. A design is presented for a bi-harmonic cantilever that has a second resonant mode at twice its first resonant mode, thereby capable of generating bi-harmonic trajectories with small forcing signals. Bi-harmonic cantilevers are fabricated by milling a small cantilever on the interior of a standard cantilever probe using a focused ion beam. Bi-harmonic drive signals are derived for standard cantilevers and bi-harmonic cantilevers. Experimental results demonstrate better than 30% improvement in measurement sensitivity using the bi-harmonic cantilever. Images obtained through bi-harmonic tapping exhibit improved sharpness and surface tracking, especially at high scan speeds and low force fields.

  17. Fast, High Resolution, and Wide Modulus Range Nanomechanical Mapping with Bimodal Tapping Mode.

    Science.gov (United States)

    Kocun, Marta; Labuda, Aleksander; Meinhold, Waiman; Revenko, Irène; Proksch, Roger

    2017-10-24

    Tapping mode atomic force microscopy (AFM), also known as amplitude modulated (AM) or AC mode, is a proven, reliable, and gentle imaging mode with widespread applications. Over the several decades that tapping mode has been in use, quantification of tip-sample mechanical properties such as stiffness has remained elusive. Bimodal tapping mode keeps the advantages of single-frequency tapping mode while extending the technique by driving and measuring an additional resonant mode of the cantilever. The simultaneously measured observables of this additional resonance provide the additional information necessary to extract quantitative nanomechanical information about the tip-sample mechanics. Specifically, driving the higher cantilever resonance in a frequency modulated (FM) mode allows direct measurement of the tip-sample interaction stiffness and, with appropriate modeling, the set point-independent local elastic modulus. Here we discuss the advantages of bimodal tapping, coined AM-FM imaging, for modulus mapping. Results are presented for samples over a wide modulus range, from a compliant gel (∼100 MPa) to stiff materials (∼100 GPa), with the same type of cantilever. We also show high-resolution (subnanometer) stiffness mapping of individual molecules in semicrystalline polymers and of DNA in fluid. Combined with the ability to remain quantitative even at line scan rates of nearly 40 Hz, the results demonstrate the versatility of AM-FM imaging for nanomechanical characterization in a wide range of applications.

  18. Development of a tapping device: a new needle insertion method for prostate brachytherapy

    International Nuclear Information System (INIS)

    Lagerburg, V; Moerland, M A; Konings, M K; Vosse, R E van de; Lagendijk, J J W; Battermann, J J

    2006-01-01

    The purpose of this study is to develop and test a tapping device for needle insertion for prostate brachytherapy. This device will tap the needle into the prostate with a certain, well-defined, amount of momentum, instead of the currently used method of pushing the needle. Because of the high needle insertion velocity, we expect prostate motion and deformation to be less compared to current methods. We measured the momentum that is applied when manually tapping the needle into the prostate and found a mean momentum of 0.50 ± 0.07 N s. The tapping device is pneumatically driven and we found that the delivered momentum increased linearly with the applied air pressure. The efficacy of the tapping device was tested on a piece of beef, placed on a freely moving and rotating platform. A significant correlation was found between the applied pressure and the rotation and displacement of the beef. Displacements and rotations were minimal for the highest pressure (4 bar) and amounted to only 2 mm and 6 deg., respectively. Higher air pressures will further reduce displacements and rotations

  19. Polyphasic Temporal Behavior of Finger-Tapping Performance: A Measure of Motor Skills and Fatigue.

    Science.gov (United States)

    Aydin, Leyla; Kiziltan, Erhan; Gundogan, Nimet Unay

    2016-01-01

    Successive voluntary motor movement involves a number of physiological mechanisms and may reflect motor skill development and neuromuscular fatigue. In this study, the temporal behavior of finger tapping was investigated in relation to motor skills and fatigue by using a long-term computer-based test. The finger-tapping performances of 29 healthy male volunteers were analyzed using linear and nonlinear regression models established for inter-tapping interval. The results suggest that finger-tapping performance exhibits a polyphasic nature, and has several characteristic time points, which may be directly related to muscle dynamics and energy consumption. In conclusion, we believe that future studies evaluating the polyphasic nature of the maximal voluntary movement will lead to the definition of objective scales that can be used in the follow up of some neuromuscular diseases, as well as, the determination of motor skills, individual ability, and peripheral fatigue through the use of a low cost, easy-to-use computer-based finger-tapping test.

  20. A Direct-Learning Approach to Acquiring a Bimanual Tapping Skill.

    Science.gov (United States)

    Michaels, Claire F; Gomes, Thábata V B; Benda, Rodolfo N

    2017-01-01

    The theory of direct learning (D. M. Jacobs & C. F. Michaels, 2007 ) has proven useful in understanding improvement in perception and exploratory action. Here the authors assess its usefulness for understanding the learning of a motor skill, bimanual tapping at a difficult phase relation. Twenty participants attempted to learn to tap with 2 index fingers at 2 Hz with a phase lag of 90° (i.e., with a right-right period of 500 ms and a right-left period of 125 ms). There were 30 trials, each with 50 tapping cycles. Computer-screen feedback informed of errors in both period and phase for each pair of taps. Participants differed dramatically in their success. Learning was assessed by identifying the succession of attractors capturing tapping over the experiment. A few participants' attractors migrated from antiphase to 90° with an appropriate period; others became attracted to a fixed right-left interval, rather than phase, with or without attraction to period. Changes in attractor loci were explained with mixed success by direct learning, inviting elaboration of the theory. The transition to interval attractors was understood as a change in intention, and was remarkable for its indifference to typical bimanual interactions.

  1. Parametric CAD and Fea Model of a Saddle Tapping Tee

    DEFF Research Database (Denmark)

    A. Kristensen, Anders Schmidt; Lund Jepsen, Kristian

    2007-01-01

     Often it is necessary to branch of a pipe section on an oilrig. This operation is often performed by making a so-called "Hot Tapping", which involves welding a pipe and a flange on to the pipe section. A spherical valve and a gate are mounted on to the flange, i.e. weld-o-let. In order to perform...... the welding operations a so-called habitat must be constructed. This habitat encapsulates the "Hot Tapping" spot and is relatively costly. Thus, to avoid weld operations on to the pipeline, a solution with clamps has been developed, i.e. a Saddle Tapping Tee. The Saddle Tapping Tee is clamped on the pipe...... is determined from paragraph K302.3.2 in ASME B31.3. A full parametric 3D CAD model of the Saddle Tapping Tee is developed where a number of user-defined parameters are controlled from an Excel spreadsheet allowing parameter studies and technical documentation to be generated effectively. The same Excel spread...

  2. Interactional synchrony in chimpanzees: Examination through a finger-tapping experiment.

    Science.gov (United States)

    Yu, Lira; Tomonaga, Masaki

    2015-05-11

    Humans often unconsciously coordinate behaviour with that of others in daily life. This interpersonal coordination, including mimicry and interactional synchrony, has been suggested to play a fundamental role in social interaction. If this coordinative behavior is socially adaptive, it may be shared with other highly social animal species. The current study targeted chimpanzees, which phylogenetically are the closest living relatives of humans and live in complex social groups, and examined whether interactional synchrony would emerge in pairs of chimpanzees when auditory information about a partner's movement was provided. A finger-tapping task was introduced via touch panels to elicit repetitive and rhythmic movement from each chimpanzee. We found that one of four chimpanzees produced significant changes in both tapping tempo and timing of the tapping relative to its partner's tap when auditory sounds were provided. Although the current results may have limitations in generalizing to chimpanzees as a species, we suggest that a finger-tapping task is one potential method to investigate interactional synchrony in chimpanzees under a laboratory setup.

  3. Bi-harmonic cantilever design for improved measurement sensitivity in tapping-mode atomic force microscopy.

    Science.gov (United States)

    Loganathan, Muthukumaran; Bristow, Douglas A

    2014-04-01

    This paper presents a method and cantilever design for improving the mechanical measurement sensitivity in the atomic force microscopy (AFM) tapping mode. The method uses two harmonics in the drive signal to generate a bi-harmonic tapping trajectory. Mathematical analysis demonstrates that the wide-valley bi-harmonic tapping trajectory is as much as 70% more sensitive to changes in the sample topography than the standard single-harmonic trajectory typically used. Although standard AFM cantilevers can be driven in the bi-harmonic tapping trajectory, they require large forcing at the second harmonic. A design is presented for a bi-harmonic cantilever that has a second resonant mode at twice its first resonant mode, thereby capable of generating bi-harmonic trajectories with small forcing signals. Bi-harmonic cantilevers are fabricated by milling a small cantilever on the interior of a standard cantilever probe using a focused ion beam. Bi-harmonic drive signals are derived for standard cantilevers and bi-harmonic cantilevers. Experimental results demonstrate better than 30% improvement in measurement sensitivity using the bi-harmonic cantilever. Images obtained through bi-harmonic tapping exhibit improved sharpness and surface tracking, especially at high scan speeds and low force fields.

  4. Tapping insertional torque allows prediction for better pedicle screw fixation and optimal screw size selection.

    Science.gov (United States)

    Helgeson, Melvin D; Kang, Daniel G; Lehman, Ronald A; Dmitriev, Anton E; Luhmann, Scott J

    2013-08-01

    There is currently no reliable technique for intraoperative assessment of pedicle screw fixation strength and optimal screw size. Several studies have evaluated pedicle screw insertional torque (IT) and its direct correlation with pullout strength. However, there is limited clinical application with pedicle screw IT as it must be measured during screw placement and rarely causes the spine surgeon to change screw size. To date, no study has evaluated tapping IT, which precedes screw insertion, and its ability to predict pedicle screw pullout strength. The objective of this study was to investigate tapping IT and its ability to predict pedicle screw pullout strength and optimal screw size. In vitro human cadaveric biomechanical analysis. Twenty fresh-frozen human cadaveric thoracic vertebral levels were prepared and dual-energy radiographic absorptiometry scanned for bone mineral density (BMD). All specimens were osteoporotic with a mean BMD of 0.60 ± 0.07 g/cm(2). Five specimens (n=10) were used to perform a pilot study, as there were no previously established values for optimal tapping IT. Each pedicle during the pilot study was measured using a digital caliper as well as computed tomography measurements, and the optimal screw size was determined to be equal to or the first size smaller than the pedicle diameter. The optimal tap size was then selected as the tap diameter 1 mm smaller than the optimal screw size. During optimal tap size insertion, all peak tapping IT values were found to be between 2 in-lbs and 3 in-lbs. Therefore, the threshold tapping IT value for optimal pedicle screw and tap size was determined to be 2.5 in-lbs, and a comparison tapping IT value of 1.5 in-lbs was selected. Next, 15 test specimens (n=30) were measured with digital calipers, probed, tapped, and instrumented using a paired comparison between the two threshold tapping IT values (Group 1: 1.5 in-lbs; Group 2: 2.5 in-lbs), randomly assigned to the left or right pedicle on each

  5. Phosphate ions as inhibiting agents for copper corrosion in chlorinated tap water

    International Nuclear Information System (INIS)

    Yohai, L.; Schreiner, W.H.; Vázquez, M.; Valcarce, M.B.

    2013-01-01

    PO 4 3− ions as corrosion inhibitor were investigated on copper in tap water in the presence of NaClO. The inhibitor was evaluated by electrochemical techniques and weight loss tests. Raman spectroscopy and X-ray photoelectron spectroscopy were used to study the passive layer. In inhibited tap water, the passive layer is thick and compact if NaClO is present. Weight-loss tests showed the inhibition of uniform dissolution and no pitting attack. When adding NaClO, Cu 3 (PO 4 ) 2 is incorporated to the passive film. Thus, phosphate ions are effective as inhibitors for copper in tap water, even when using high dosages of biocides. - Highlights: ► Changes in the copper corrosion after adding phosphate to tap water were analyzed. ► When NaClO and phosphates are present, Cu 3 (PO 4 ) 2 participates of the surface film. ► In the absence of biocide the surface film contains a mixture of Cu 2 O, CuO and Cu(OH) 2 . ► PO 4 3− is an effective inhibitor for Cu in tap water containing high NaClO dosages

  6. Comparison of timing and force control of foot tapping between elderly and young subjects.

    Science.gov (United States)

    Takimoto, Koji; Takebayashi, Hideaki; Miyamoto, Kenzo; Takuma, Yutaka; Inoue, Yoshikazu; Miyamoto, Shoko; Okabe, Takao; Okuda, Takahiro; Kaba, Hideto

    2016-06-01

    [Purpose] To examine the ability of young and elderly individuals to control the timing and force of periodic sequential foot tapping. [Subjects and Methods] Participants were 10 young (age, 22.1 ± 4.3 years) and 10 elderly individuals (74.8 ± 6.7 years) who were healthy and active. The foot tapping task consisted of practice (stimulus-synchronized tapping with visual feedback) and recall trials (self-paced tapping without visual feedback), periodically performed in this order, at 500-, 1,000-, and 2,000-ms target interstimulus-onset intervals, with a target force of 20% maximum voluntary contraction of the ankle plantar-flexor muscle. [Results] The coefficients of variation of force and intertap interval, used for quantifying the steadiness of the trials, were significantly greater in the elderly than in the young individuals. At the 500-ms interstimulus-onset interval, age-related effects were observed on the normalized mean absolute error of force, which was used to quantify the accuracy of the trials. The coefficients of variation of intertap interval for elderly individuals were significantly greater in the practice than in the recall trials at the 500- and 1,000-ms interstimulus-onset intervals. [Conclusion] The elderly individuals exhibited greater force and timing variability than the young individuals and showed impaired visuomotor processing during foot tapping sequences.

  7. Power Loss Minimization for Transformers Connected in Parallel with Taps Based on Power Chargeability Balance

    Directory of Open Access Journals (Sweden)

    Álvaro Jaramillo-Duque

    2018-02-01

    Full Text Available In this paper, a model and solution approach for minimizing internal power losses in Transformers Connected in Parallel (TCP with tap-changers is proposed. The model is based on power chargeability balance and seeks to keep the load voltage within an admissible range. For achieving this, tap positions are adjusted in such a way that all TCP are set in similar/same power chargeability. The main contribution of this paper is the inclusion of several construction features (rated voltage, rated power, voltage ratio, short-circuit impedance and tap steps in the minimization of power losses in TCP that are not included in previous works. A Genetic Algorithm (GA is used for solving the proposed model that is a system of nonlinear equations with discrete decision variables. The GA scans different sets for tap positions with the aim of balancing the power supplied by each transformer to the load. For this purpose, a fitness function is used for minimizing two conditions: The first condition consists on the mismatching between power chargeability for each transformer and a desired chargeability; and the second condition is the mismatching between the nominal load voltage and the load voltage obtained by changing the tap positions. The proposed method is generalized for any given number of TCP and was implemented for three TCP, demonstrating that the power losses are minimized and the load voltage remains within an admissible range.

  8. Levels of major and trace elements, including rare earth elements, and ²³⁸U in Croatian tap waters.

    Science.gov (United States)

    Fiket, Željka; Rožmarić, Martina; Krmpotić, Matea; Benedik, Ljudmila

    2015-05-01

    Concentrations of 46 elements, including major, trace, and rare earth elements, and (238)U in Croatian tap waters were investigated. Selected sampling locations include tap waters from various hydrogeological regions, i.e., different types of aquifers, providing insight into the range of concentrations of studied elements and (238)U activity concentrations in Croatian tap waters. Obtained concentrations were compared with the Croatian maximum contaminant levels for trace elements in water intended for human consumption, as well as WHO and EPA drinking water standards. Concentrations in all analyzed tap waters were found in accordance with Croatian regulations, except tap water from Šibenik in which manganese in concentration above maximum permissible concentration (MPC) was measured. Furthermore, in tap water from Osijek, levels of arsenic exceeded the WHO guidelines and EPA regulations. In general, investigated tap waters were found to vary considerably in concentrations of studied elements, including (238)U activity concentrations. Causes of variability were further explored using statistical methods. Composition of studied tap waters was found to be predominately influenced by hydrogeological characteristics of the aquifer, at regional and local level, the existing redox conditions, and the household plumbing system. Rare earth element data, including abundances and fractionation patterns, complemented the characterization and facilitated the interpretation of factors affecting the composition of the analyzed tap waters.

  9. Comparison of bone-conducted vibration for eliciting ocular vestibular-evoked myogenic potentials: forehead versus mastoid tapping.

    Science.gov (United States)

    Tseng, Chia-Chen; Wang, Shou-Jen; Young, Yi-Ho

    2012-02-01

    This study compared bone-conducted vibration (BCV) stimuli at forehead (Fz) and mastoid sites for eliciting ocular vestibular-evoked myogenic potentials (oVEMPs). Prospective study. University hospital. Twenty healthy subjects underwent oVEMP testing via BCV stimuli at Fz and mastoid sites. Another 50 patients with unilateral Meniere's disease also underwent oVEMP testing. All healthy subjects showed clear oVEMPs via BCV stimulation regardless of the tapping sites. The right oVEMPs stimulated by tapping at the right mastoid had earlier nI and pI latencies and a larger nI-pI amplitude compared with those stimulated by tapping at the Fz and left mastoid. Similar trends were also observed in left oVEMPs. However, the asymmetry ratio did not differ significantly between the ipsilateral mastoid and Fz sites. Clinically, tapping at the Fz revealed absent oVEMPs in 28% of Meniere's ears, which decreased to 16% when tapping at the ipsilesional (hydropic) mastoid site, exhibiting a significant difference. Tapping at the ipsilateral mastoid site elicits earlier oVEMP latencies and larger oVEMP amplitudes when compared with tapping at the Fz site. Thus, tapping at the Fz site is suggested to screen for the otolithic function, whereas tapping at the ipsilesional mastoid site is suitable for evaluating residual otolithic function.

  10. Tunable complex-valued multi-tap microwave photonic filter based on single silicon-on-insulator microring resonator.

    Science.gov (United States)

    Lloret, Juan; Sancho, Juan; Pu, Minhao; Gasulla, Ivana; Yvind, Kresten; Sales, Salvador; Capmany, José

    2011-06-20

    A complex-valued multi-tap tunable microwave photonic filter based on single silicon-on-insulator microring resonator is presented. The degree of tunability of the approach involving two, three and four taps is theoretical and experimentally characterized, respectively. The constraints of exploiting the optical phase transfer function of a microring resonator aiming at implementing complex-valued multi-tap filtering schemes are also reported. The trade-off between the degree of tunability without changing the free spectral range and the number of taps is studied in-depth. Different window based scenarios are evaluated for improving the filter performance in terms of the side-lobe level.

  11. Tap Water Hydraulic Control Systems - Design and Industrial Applications. Chapter 7 in Advances in Hydraulic Control Systems

    DEFF Research Database (Denmark)

    Conrad, Finn

    Deals with development and design of modern tap water hydraulic components and systems, in particalar the Danfoss Nessie-family of components and systems working with pure tap water without any kind of additives. Typical industrial applications are presented and the perspectives of new industrial...... applications and the environmental benefits are in focus, in particular in the food processing industry and in fire-fighting systems.......Deals with development and design of modern tap water hydraulic components and systems, in particalar the Danfoss Nessie-family of components and systems working with pure tap water without any kind of additives. Typical industrial applications are presented and the perspectives of new industrial...

  12. Investigation of Natural Radioactivity in the Tap and Spring Water in Yaounde Town, Cameroon

    International Nuclear Information System (INIS)

    Lydie, R.M.; Hakam, O.K.; Choukri, A.; Lydie, R.M.; Hakam, O.K.; Choukri, A.

    2013-01-01

    The natural radionuclide concentrations in the tap and springs water in Yaounde town, capital of Cameroon with a population of 3.5 million inhabitants were estimated by gamma spectrometry, using both well calibrated Canberra NaI(Tl) and HPGe detector systems. Tap water samples were collected during the dry and the rainy seasons, respectively in December 2002 and July 2003 and spring water samples were collected in August 2010. The radionuclides observed with regularity belonged to the series decay naturally occurring radionuclides headed by 238 U and 232 Th as well as the non-series nuclide 40 K. Assuming an individual daily consumption of 1 litre of water, the average annual intake for these populations is 3821 Bq/y for tap water and 1161 Bq/y for spring water.

  13. Study of tapping process of carbon fiber reinforced plastic composites/AA7075 stacks

    Science.gov (United States)

    D'Orazio, Alessio; Mehtedi, Mohamad El; Forcellese, Archimede; Nardinocchi, Alessia; Simoncini, Michela

    2018-05-01

    The present investigation aims at studying the tapping process of a three-layer stack constituted by two CFRP layers and a core plate in AA7075 aluminum alloy. The CFRP laminates were obtained by a pre-impregnated woven sample made up of T700 carbon fibers and a thermoset epoxy matrix. Tapping experiments were performed on a 5-axis machining center instrumented with a dynamometer to measure thrust force generated during process. A high-speed steel tool, coated with nanocomposite TiAlN, was used. According to the tool manufacturer recommendations, rotational speed and feed rate were 800 rpm and 1000 mm/min, respectively. Similar thrust force time history responses were obtained by tapping different holes, even though the vertical force increases with number of threaded holes. Furthermore, a quantitative evaluation of delamination at the periphery of entry holes was carried out. The delamination at the entry hole strongly increases with number of threaded holes.

  14. On the TAP Free Energy in the Mixed p-Spin Models

    Science.gov (United States)

    Chen, Wei-Kuo; Panchenko, Dmitry

    2018-05-01

    Thouless et al. (Phys Mag 35(3):593-601, 1977), derived a representation for the free energy of the Sherrington-Kirkpatrick model, called the TAP free energy, written as the difference of the energy and entropy on the extended configuration space of local magnetizations with an Onsager correction term. In the setting of mixed p-spin models with Ising spins, we prove that the free energy can indeed be written as the supremum of the TAP free energy over the space of local magnetizations whose Edwards-Anderson order parameter (self-overlap) is to the right of the support of the Parisi measure. Furthermore, for generic mixed p-spin models, we prove that the free energy is equal to the TAP free energy evaluated on the local magnetization of any pure state.

  15. Physics evaluation for testino. of RAPS and TAPS fuel pins in CIRUS pressurised water loop

    International Nuclear Information System (INIS)

    John, Benjamin; Paul, O.P.K.

    1976-01-01

    Relevant calculations carried out to assess the reactivity effect, heat generation and other parameters for testing of RAPS and TAPS fuel pins in the Cirus pressurised water loop are summarised. The Cirus neutron flux level being low, in order to simulate the RAPS design heat rating of ∫ Kdtheta = 40 w/cm, the required plutonium enrichment in mixed plutonium uranium oxide fuel pin was worked out. The results showed that a PuO 2 enrichment of 1.5 wt percent would be necessary to meet the above requirement. The analysis for the TAPS pin indicated that the desired heat flux of 115w/cm 2 cannot be obtained in the Cirus loop with either a 7 pin cluster geometry, or with a single pin with the enrichment level as used in TAPS pin. Lattice code DUMLAC and the core simulation code AECLHEX were used for these studies. (author)

  16. Balance outcomes following a tap dance program for a child with congenital myotonic muscular dystrophy.

    Science.gov (United States)

    Biricocchi, Charlanne; Drake, JaimeLynn; Svien, Lana

    2014-01-01

    This case report describes the effects of a 6-week progressive tap dance program on static and dynamic balance for a child with type 1 congenital myotonic muscular dystrophy (congenital MMD1). A 6-year-old girl with congenital MMD1 participated in a 1-hour progressive tap dance program. Classes were held once a week for 6 consecutive weeks and included 3 children with adaptive needs and 1 peer with typical development. The Bruininks-Oseretsky Test of Motor Proficiency, second edition (BOT-2) balance subsection and the Pediatric Balance Scale were completed at the beginning of the first class and the sixth class. The participant's BOT-2 score improved from 3 to 14. Her Pediatric Balance Scale score did not change. Participation in a progressive tap dance class by a child with congenital MMD1 may facilitate improvements in static and dynamic balance.

  17. Predicting consumer preferences for mineral composition of bottled and tap water.

    Science.gov (United States)

    Platikanov, Stefan; Hernández, Alejandra; González, Susana; Luis Cortina, Jose; Tauler, Roma; Devesa, Ricard

    2017-01-01

    The overall liking for taste of water was correlated with the mineral composition of selected bottled and tap waters. Sixty-nine untrained volunteers assessed and rated twenty-five different commercial bottled and tap waters from. Water samples were physicochemical characterised by analysing conductivity, pH, total dissolved solids (TDS) and major anions and cations: HCO 3 - , SO 4 2- , Cl - , NO 3 - , Ca 2+ , Mg 2+ , Na + , and K + . Residual chlorine levels were also analysed in the tap water samples. Globally, volunteers preferred waters rich in calcium bicarbonate and sulfate, rather than in sodium chloride. This study also demonstrated that it was possible to accurately predict the overall liking by a Partial Least Squares regression using either all measured physicochemical parameters or a reduced number of them. These results were in agreement with previously published results using trained panellists. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Nuclear power plant personnel qualifications and training: TAPS: the task analysis profiling system. Volume 2

    International Nuclear Information System (INIS)

    Jorgensen, C.C.

    1985-06-01

    This report discusses an automated task analysis profiling system (TAPS) designed to provide a linking tool between the behaviors of nuclear power plant operators in performing their tasks and the measurement tools necessary to evaluate their in-plant performance. TAPS assists in the identification of the entry-level skill, knowledge, ability and attitude (SKAA) requirements for the various tasks and rapidly associates them with measurement tests and human factors principles. This report describes the development of TAPS and presents its first demonstration. It begins with characteristics of skilled human performance and proceeds to postulate a cognitive model to formally describe these characteristics. A method is derived for linking SKAA characteristics to measurement tests. The entire process is then automated in the form of a task analysis computer program. The development of the program is detailed and a user guide with annotated code listings and supporting test information is provided

  19. On the formal equivalence of the TAP and thermodynamic methods in the SK model

    International Nuclear Information System (INIS)

    Cavagna, Andrea; Giardina, Irene; Parisi, Giorgio; Mezard, Marc

    2003-01-01

    We revisit two classic Thouless-Anderson-Palmer (TAP) studies of the Sherrington-Kirkpatrick model (Bray A J and Moore M A 1980 J. Phys. C: Solid State Phys. 13 L469; De Dominicis C and Young A P 1983 J. Phys. A: Math. Gen. 16 2063). By using the Becchi-Rouet-Stora-Tyutin (BRST) supersymmetry, we prove the general equivalence of TAP and replica partition functions, and show that the annealed calculation of the TAP complexity is formally identical to the quenched thermodynamic calculation of the free energy at one step level of replica symmetry breaking. The complexity we obtain by means of the BRST symmetry turns out to be considerably smaller than the previous non-symmetric value

  20. Transversus abdominis plane (TAP) block after robot-assisted laparoscopic hysterectomy

    DEFF Research Database (Denmark)

    Torup, H; Bøgeskov, M; Hansen, E G

    2015-01-01

    BACKGROUND: Transversus abdominis plane (TAP) block is widely used as a part of pain management after various abdominal surgeries. We evaluated the effect of TAP block as an add-on to the routine analgesic regimen in patients undergoing robot-assisted laparoscopic hysterectomy. METHODS......: In a prospective blinded study, 70 patients scheduled for elective robot-assisted laparoscopic hysterectomy were randomised to receive either TAP block (ropivacaine 0.5%, 20 ml on each side) or sham block (isotonic saline 0.9%, 20 ml on each side). All patients had patient-controlled analgesia (PCA) with morphine...... and Nonsteroidal anti-inflammatory drugs (NSAID) treatment, had no effect on morphine consumption, VAS pain scores, or frequency of nausea and vomiting after robot-assisted laparoscopic hysterectomy compared with paracetamol and NSAID alone....

  1. Cross-Cultural Influences on Rhythm Processing: Reproduction, Discrimination, and Beat Tapping

    Directory of Open Access Journals (Sweden)

    Daniel J Cameron

    2015-04-01

    Full Text Available The structures of musical rhythm differ between cultures, despite the fact that the ability to synchronize one’s movements to musical rhythms appears to be universal. To measure the influence of culture on rhythm processing, we tested East African and North American adults on the perception, production, and beat tapping of rhythms derived from East African and Western music. To assess rhythm perception, participants identified whether pairs of rhythms were same or different. To assess rhythm production, participants reproduced rhythms after hearing them. To assess beat tapping, participants tapped the beat along with repeated rhythms. We expected that performance in all three tasks would be influenced both by the culture of the participant and by the culture of the rhythm. Specifically, we predicted that a participant’s ability to discriminate, reproduce, and accurately tap the beat would be better for rhythms from their own culture than for rhythms from another culture. In the rhythm discrimination task, there were no differences in discriminating culturally familiar and unfamiliar rhythms. In the rhythm reproduction task, both groups reproduced East African rhythms more accurately than Western rhythms, but East African participants also showed an effect of cultural familiarity, leading to a significant interaction. In the beat tapping task, participants in both groups tapped the beat more accurately for culturally familiar than unfamiliar rhythms. The results demonstrate that culture does influence the processing of musical rhythm. In terms of the function of musical rhythm, our results are consistent with theories that musical rhythm enables synchronization. Musical rhythm may foster musical cultural identity by enabling within-group synchronization to music, perhaps supporting social cohesion.

  2. Association of LMP/TAP gene polymorphisms with tuberculosis susceptibility in Li population in China.

    Directory of Open Access Journals (Sweden)

    Danmei Wang

    Full Text Available BACKGROUND: Tuberculosis (TB is a contagious disease affected by multiple genetic and environmental factors. Several association studies have suggested that cellular immune response is vital for controlling and preventing of tuberculosis infection. Low molecular weight polypeptides (LMPs and transporters with antigen processing (TAPs are the main molecules in the processing and presentation pathway for intracellular antigens. This study was performed to elucidate whether these antigen-processing genes (LMP/TAP polymorphisms could be associated with the risk of tuberculosis infection in China. METHODOLOGY/PRINCIPAL FINDINGS: We recruited 205 active pulmonary tuberculosis patients and 217 normal controls from Li population for this study. Four polymorphisms of LMP/TAP genes were determined by PCR-RFLP assay and haplotypes were constructed by software PHASE 1.0. Of the total four polymorphisms, genotype frequencies of LMP7 AA homozygote and CA heterozygote were significantly greater among cases compared to controls, with odds ratio of 3.77 (95% CI: 1.60-8.89; P = 0.002 and 2.97 (95% CI: 1.80-4.90; P<0.0001, respectively. The genotypes of TAP1-2 GG homozygote and AG heterozygote were more frequent in subjects with TB than in controls, with odds ratio of 3.94 (95% CI: 1.82-8.53; P = 0.001 and 2.87 (95% CI: 1.75-4.71; P<0.0001, respectively. Similarly, we found that haplotype B which carried LMP7 and TAP1-2 variations significantly increased the susceptibility to TB (OR = 3.674, 95% CI: 2.254-5.988; P<0.0001. Moreover, it is noteworthy that the homozygote of wild haplotype A (A/A may be a strong protection for TB infection. CONCLUSIONS: Our findings suggested that LMP/TAP gene polymorphisms might be risk factors for TB infection among Li population in China.

  3. Finger tapping impairments are highly sensitive for evaluating upper motor neuron lesions.

    Science.gov (United States)

    Shirani, Afsaneh; Newton, Braeden D; Okuda, Darin T

    2017-03-21

    Identifying highly sensitive and reliable neurological exam components are crucial in recognizing clinical deficiencies. This study aimed to investigate finger tapping performance differences between patients with CNS demyelinating lesions and healthy control subjects. Twenty-three patients with multiple sclerosis or clinically isolated syndrome with infratentorial and/or cervical cord lesions on MRI, and 12 healthy controls were videotaped while tapping the tip of the index finger against the tip and distal crease of the thumb using both the dominant and non-dominant hand. Videos were assessed independently by 10 evaluators (three MS neurologists, four neurology residents, three advanced practice providers). Sensitivity and inter-evaluator reliability of finger tapping interpretations were calculated. A total of 1400 evaluations (four videos per each of the 35 subjects evaluated by 10 independent providers) were obtained. Impairments in finger tapping against the distal thumb crease of the non-dominant hand, identified by neurologists, had the greatest sensitivity (84%, p tapping against the thumb crease was more sensitive than the thumb tip across all categories of providers. The best inter-evaluator reliability was associated with neurologists' evaluations for the thumb crease of the non-dominant hand (kappa = 0.83, p tapping against the distal thumb crease of the non-dominant hand was a more sensitive technique for detecting impairments related to CNS demyelinating lesions. Our findings highlight the importance of precise examinations of the non-dominant side where impaired fine motor control secondary to an upper motor injury might be detectable earlier than the dominant side.

  4. Evidence for repetitive load in the trapezius muscle during a tapping task.

    Science.gov (United States)

    Tomatis, L; Müller, C; Nakaseko, M; Läubli, T

    2012-08-01

    Many studies describe the trapezius muscle activation pattern during repetitive key-tapping focusing on continuous activation. The objectives of this study were to determine whether the upper trapezius is phasically active during supported key tapping, whether this activity is cross-correlated with forearm muscle activity, and whether trapezius activity depends on key characteristic. Thirteen subjects (29.7 ± 11.4 years) were tested. Surface EMG of the finger's extensor and flexor and of the trapezius muscles, as well as the key on-off signal was recorded while the subject performed a 2-min session of key tapping at 4 Hz. The linear envelopes obtained were cut into single tapping cycles extending from one onset to the next onset signal and subsequently time-normalized. Effect size between mean range and maximal standard deviation was calculated to determine as to whether a burst of trapezius muscle activation was present. Cross-correlation was used to determine the time-lag of the activity bursts between forearm and trapezius muscles. For each person the mean and standard deviation of the cross-correlations coefficient between forearm muscles and trapezius were determined. Results showed a burst of activation in the trapezius muscle during most of the tapping cycles. The calculated effect size was ≥0.5 in 67% of the cases. Cross-correlation factors between forearm and trapezius muscle activity were between 0.75 and 0.98 for both extensor and flexor muscles. The cross-correlated phasic trapezius activity did not depend on key characteristics. Trapezius muscle was dynamically active during key tapping; its activity was clearly correlated with forearm muscles' activity.

  5. Short Communication. Resin tapping activity as a contribution to the management of maritime pine forest

    Directory of Open Access Journals (Sweden)

    Amélia Palma

    2016-07-01

    Full Text Available Aim of the study: In this work potential resin yield in a region of high forest ability where maritime pine is the main species was estimated in order to understand the viability of promoting resin exploitation. Area of study: This study was conducted in Castro Daire County in central region of Portugal. Material and methods: To quantify the resin yield of trees tapped for the first time two plots were installed in a maritime pine stand with average tree age 65 years. Before the beginning of the resin tapping, dendrometric tree variables were measured. Also, in a neighbouring stand, 25 trees were selected to check the relation between tree dbh and resin yield. Gum resin from every tree was weighted during the season. Estimates of potential resin yield in Castro Daire County were made based on data from National Forest Inventory plots, resin tapping legislation and resin yield values obtained in the field. Two scenarios were considered: high and low resin yield. To understand the intentions of forest owners towards restarting resin tapping activity 16 maritime pine forest owners were interviewed. Main results: The results point out a high yield potential capacity for gum resin production in the County: values between 2,025 and 5,873 tons were obtained. Research highlights: Results may highlight the important socio-economical role of the resin tapping activity and can be used to support national forest policies to the resin sector and give forest owners motivation to reactivate resin tapping activity. Keywords: non-wood forest product; resin yield potential; forest owner.

  6. Risk characterization of methyl tertiary butyl ether (MTBE) in tap water.

    Science.gov (United States)

    Stern, B R; Tardiff, R G

    1997-12-01

    Methyl tertiary butyl ether (MTBE) can enter surface water and groundwater through wet atmospheric deposition or as a result of fuel leaks and spills. About 30% of the U.S. population lives in areas where MTBE is in regular use. Ninety-five percent of this population is unlikely to be exposed to MTBE in tap water at concentrations exceeding 2 ppb, and most will be exposed to concentrations that are much lower and may be zero. About 5% of this population may be exposed to higher levels of MTBE in tap water, resulting from fuel tank leaks and spills into surface or groundwater used for potable water supplies. This paper describes the concentration ranges found and anticipated in surface and groundwater, and estimates the distribution of doses experienced by humans using water containing MTBE to drink, prepare food, and shower/bathe. The toxic properties (including potency) of MTBE when ingested, inhaled, and in contact with the skin are summarized. Using a range of human toxic potency values derived from animal studies, margins of exposure (MOE) associated with alternative chronic exposure scenarios are estimated to range from 1700 to 140,000. Maximum concentrations of MTBE in tap water anticipated not to cause adverse health effects are determined to range from 700 to 14,000 ppb. The results of this analysis demonstrate that no health risks are likely to be associated with chronic and subchronic human exposures to MTBE in tap water. Although some individuals may be exposed to very high concentrations of MTBE in tap water immediately following a localized spill, these exposures are likely to be brief in duration due to large-scale dilution and rapid volatilization of MTBE, the institution of emergency response and remediation measures to minimize human exposures, and the low taste and odor thresholds of MTBE which ensure that its presence in tap water is readily detected at concentrations well below the threshold for human injury.

  7. Harmonic and power balance tools for tapping-mode atomic force microscope

    International Nuclear Information System (INIS)

    Sebastian, A.; Salapaka, M. V.; Chen, D. J.; Cleveland, J. P.

    2001-01-01

    The atomic force microscope (AFM) is a powerful tool for investigating surfaces at atomic scales. Harmonic balance and power balance techniques are introduced to analyze the tapping-mode dynamics of the atomic force microscope. The harmonic balance perspective explains observations hitherto unexplained in the AFM literature. A nonconservative model for the cantilever - sample interaction is developed. The energy dissipation in the sample is studied and the resulting power balance equations combined with the harmonic balance equations are used to estimate the model parameters. Experimental results confirm that the harmonic and power balance tools can be used effectively to predict the behavior of the tapping cantilever. [copyright] 2001 American Institute of Physics

  8. JPRS Report, East Asia, Vietnam: TAP CHI CONG SAN, No. 10, October 1987

    Science.gov (United States)

    1988-02-09

    Followers in the Countries of Latin America [ Tran Anh] 48 JPRS-ATC-88-002 9 February 1988 VIETNAM: TAP CHI CONG SAN No 10, October 1987 [Except...character is not simply an ideological-political category applied in literature. Our party, as Truong Chinh said at the Third National Literature and Art...Hanoi TAP CHI CONG SAN in Vietnamese No 10, Oct 87pp 39-42 [Article by Nguyen Dang Quang, assistant editor-in-chief of GIAO DUC LY LUAN Journal

  9. A theory of solving TAP equations for Ising models with general invariant random matrices

    DEFF Research Database (Denmark)

    Opper, Manfred; Çakmak, Burak; Winther, Ole

    2016-01-01

    We consider the problem of solving TAP mean field equations by iteration for Ising models with coupling matrices that are drawn at random from general invariant ensembles. We develop an analysis of iterative algorithms using a dynamical functional approach that in the thermodynamic limit yields...... the iteration dependent on a Gaussian distributed field only. The TAP magnetizations are stable fixed points if a de Almeida–Thouless stability criterion is fulfilled. We illustrate our method explicitly for coupling matrices drawn from the random orthogonal ensemble....

  10. Deployment Efficiency and Barrier Effectiveness Testing of a Temporary Anti-Personnel (TAP) Barrier System.

    Energy Technology Data Exchange (ETDEWEB)

    Allen, David James [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hedrick, Charles D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Martinez, Ruben [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    This report documents tests conducted by Sandia National Laboratories (SNL) on behalf of the U.S. Department of State to evaluate a temporary anti-personnel (TAP) barrier system developed by Mitigation Technologies. For this, the SNL Denial and Structural Assessment department developed a test protocol for the evaluation of the TAP barrier system on the basis of deployment efficiency and barrier effectiveness against a riotous/mob attack threat. The test protocol was then executed by SNL personnel and the results of the testing are documented.

  11. Evaluation of the General Atomic codes TAP and RECA for HTGR accident analyses

    International Nuclear Information System (INIS)

    Ball, S.J.; Cleveland, J.C.; Sanders, J.P.

    1978-01-01

    The General Atomic codes TAP (Transient Analysis Program) and RECA (Reactor Emergency Cooling Analysis) are evaluated with respect to their capability for predicting the dynamic behavior of high-temperature gas-cooled reactors (HTGRs) for postulated accident conditions. Several apparent modeling problems are noted, and the susceptibility of the codes to misuse and input errors is discussed. A critique of code verification plans is also included. The several cases where direct comparisons could be made between TAP/RECA calculations and those based on other independently developed codes indicated generally good agreement, thus contributing to the credibility of the codes

  12. Studies to overcome the manufacturing problems in blast furnace tap hole clay of Integrated Steel Plants: Experimental approach

    Science.gov (United States)

    Siva kumar, R.; Mohammed, Raffi; Srinivasa Rao, K.

    2018-03-01

    Integrated Steel Plants commonly uses Blast Furnace route for iron production which accounts for over 60 % of the world iron output. Blast Furnace runs for ten to twenty years without repairing hearth walls and Tap Hole (TH). Tap hole is an outlet for hot metal produced in a Blast Furnace and run from the shell of the furnace into the interior allowing access to the molten material. Tapping is the term used for drilling a hole through the tap hole which allows the molten iron and slag to flow out. In Iron making process, removal of liquid iron from furnace and sending it for steel making is known as cast house practice. For tapping liquid iron and operating the tap hole requires a special type of clay. Tap hole clay (THC) used to stop the flow of liquid iron and slag from the blast furnace. Present work deals with the study on manufacturing of THC at Visakhapatnam Steel Plant and problems related to manufacturing. Experiments were conducted to solve the identified problems and results are furnished in detail. The findings can improve the manufacturing process and improve the productivity of tap hole clay.

  13. Metabolic effect of TAp63α : enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense

    NARCIS (Netherlands)

    D'Alessandro, Angelo; Amelio, Ivano; Berkers, Celia R; Antonov, Alexey; Vousden, Karen H; Melino, Gerry; Zolla, Lello

    2014-01-01

    TAp63α is a member of the p53 family, which plays a central role in epithelial cancers. Recently, a role has emerged for p53 family members in cancer metabolic modulation. In order to assess whether TAp63α plays a role in cancer metabolism, we exploited p53-null osteosarcoma Tet-On Saos-2 cells, in

  14. Primary stability and self-tapping blades: biomechanical assessment of dental implants in medium-density bone.

    Science.gov (United States)

    Kim, Yung-Soo; Lim, Young-Jun

    2011-10-01

    The aim of this biomechanical study was to assess the influence of self-tapping blades in terms of primary implant stability between implants with self-tapping blades and implants without self-tapping blades using five different analytic methods, especially in medium-density bone. Two different types of dental implants (4 × 10 mm) were tested: self-tapping and non-self-tapping. The fixture design including thread profiles was exactly the same between the two groups; the only difference was the presence of cutting blades on one half of the apical portion of the implant body. Solid rigid polyurethane blocks with corresponding densities were selected to simulate medium-density bone. Five mechanical assessments (insertion torque, resonance frequency analysis [RFA], reverse torque, pull-out and push in test) were performed for primary stability. Implants without self-tapping blades showed significantly higher values (P0.05). The outcomes of the present study indicate that the implant body design without self-tapping blades has a good primary stability compared with that with self-tapping blades in medium-density bone. Considering the RFA, a distinct layer of cortical bone on marginal bone will yield implant stability quotient values similar to those in medium-bone density when implants have the same diameter. © 2011 John Wiley & Sons A/S.

  15. Local Talent: By Tapping into the Resources Just outside Their School Walls, Music Teachers Can Help Broaden Their Students' Horizons

    Science.gov (United States)

    Randall, Mac

    2009-01-01

    Many music teachers across the country have learned how beneficial it can be to tap into the communities around them. The author discusses how music teachers can help broaden their students' horizons by tapping into the resources just outside their school walls. One way is by employing local talents. Another is to put an ad in nearby music stores,…

  16. Bremsstrahlung properties in 129 Xe + 197 Au reactions at 44 MeV/Nucleon = setting of Taps

    International Nuclear Information System (INIS)

    Merrouch, R.; Delagrange, H.; Lefevre, F.; Mittig, W.; Ostendorf, R.; Schutz, Y.; Berg, F.D.; Kuhn, W.; Metag, V.; Novotny, R.; Pfeiffer, M.; Boonstra, A.L.; Loehner, H.; Venema, L.B.; Wilschut, H.W.; Ardouin, D.; Dabrowski, H.; Erazmus, B.; Lebrun, D.; Sezac, L.; Matulewicz, T.; Ballester, F.; Casal, E.; Diaz, J.; Ferrero, J.L.; Marques, M.; Martinez, G.; Sujkowski, Z.

    1991-01-01

    The start of operation, at GANIL, of the TAPS photon multidetector is described, as well as the various phases of data exploitation leading to pure photon events. Characteristics of the Bremstrahlung emission in 129 Xe + 197 Au at 44 MeV per nucleon are presented. The good agreement between our results and similar data confirms the good operation of TAPS [fr

  17. Tunable complex-valued multi-tap microwave photonic filter based on single silicon-oninsulator microring resonator

    DEFF Research Database (Denmark)

    Lloret, Juan; Sancho, Juan; Pu, Minhao

    2011-01-01

    A complex-valued multi-tap tunable microwave photonic filter based on single silicon-on-insulator microring resonator is presented. The degree of tunability of the approach involving two, three and four taps is theoretical and experimentally characterized, respectively. The constraints of exploit...

  18. Perceptions of Tap Water and School Water Fountains and Association with Intake of Plain Water and Sugar-Sweetened Beverages

    Science.gov (United States)

    Onufrak, Stephen J.; Park, Sohyun; Sharkey, Joseph R.; Merlo, Caitlin; Dean, Wesley R.; Sherry, Bettylou

    2014-01-01

    Background: Little is known regarding youth perceptions of tap water and school water fountains and how these relate to water and sugar-sweetened beverage (SSB) intake. Methods: We used national 2010 YouthStyles data to assess perceptions of tap water and school water fountains and associations with water and SSB intake. Results: Nearly 1 in 5…

  19. Theoretical atomic physics code development III TAPS: A display code for atomic physics data

    International Nuclear Information System (INIS)

    Clark, R.E.H.; Abdallah, J. Jr.; Kramer, S.P.

    1988-12-01

    A large amount of theoretical atomic physics data is becoming available through use of the computer codes CATS and ACE developed at Los Alamos National Laboratory. A new code, TAPS, has been written to access this data, perform averages over terms and configurations, and display information in graphical or text form. 7 refs., 13 figs., 1 tab

  20. The Beat Goes on: Rhythmic Modulation of Cortical Potentials by Imagined Tapping

    Science.gov (United States)

    Osman, Allen; Albert, Robert; Ridderinkhof, K. Richard; Band, Guido; van der Molen, Maurits

    2006-01-01

    A frequency analysis was used to tag cortical activity from imagined rhythmic movements. Participants synchronized overt and imagined taps with brief visual stimuli presented at a constant rate, alternating between left and right index fingers. Brain potentials were recorded from across the scalp and topographic maps made of their power at the…

  1. Analysis of transients for NPP with VVER-440 using the code SiTAP

    International Nuclear Information System (INIS)

    Kalinenko, V.

    1994-06-01

    The report contains analysis of transients ''Loop connection'' and ''Steam generator tube rupture'' for nuclear power plants (NPP) with VVER-440. To obtain more detailed information about NPP's dynamic characteristics, various variants of initial and boundary conditions are considerd. Calculation of these transients was performed using the SiTAP code developed at the Nuclear Safety Institute of the Russian Research Centre ''Kurchatov Institute''. SiTAP code is a multifunctional computer tool for fast analysis of transient and accidental processes of VVER type reactors for engineers working in the field of NPP dynamics. SiTAP can be used form comparative analysis of several variants of accident scenarios to find out the conditions leading to most serious consequences from a safety point of view. In such cases, additional analyses using best-estimate codes should be carried out. The results of SiTAP for a faulty loop connection leading to a boron dilution accident are intended to be used as boundary conditions for a more detailed anlaysis with the aid of the three-dimensional reactor core model DYN3D, developed in the Research Centre Rossendorf for the simulation of reactivity initiated accidents. (orig.)

  2. Analysis of the Difference of Radon Concentration between Water Treatment Plant and Tap water in house

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jeongil; Yoo, Donghan; Kim, Heereyoung [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

    2013-05-15

    As importance for the health, measurements and analysis about radon is active recently. Especially, radon concentration measurement about underground water which people drink was been carried out by the environment organizations in Korea and has been hot-issued because of the high radon concentration in water source. In present study, the difference of radon concentration among water source, water treatment plant and tap water in house is analyzed. It makes sense that the radon concentration in water treatment plant can represent the radon concentration in the tap water. Through the above experiments, the difference of the radon concentration between water treatment plant and tap water in house is figured out. It contributes to confirm more specific basis for estimating the annual radon exposure for the public. With further experiments and analysis, it is thought that it will be used as tool to assess more qualitatively for the radon concentration in tap water. Finally, this Fundamental approach will help in making new regulations about radon.

  3. Development and Deployment of the Purdue TAP Green Enterprise Development Program

    Science.gov (United States)

    Rogers, Ethan A.

    2013-01-01

    Purdue University--Mechanical, Engineering, and Technology (MET) faculty and Purdue Technical Assistance Program (TAP) staff partnered with the Society of Manufacturing Engineers (SME) to create a new workforce training program and certificate exam in the field of green manufacturing. This article describes how the body of knowledge for the…

  4. Putting in action the 4π γ multidetector TAPS at Ganil

    International Nuclear Information System (INIS)

    Merrouch, R.

    1991-04-01

    The study of the hard photons production originating in heavy ion collisions from bremstrahlung radiation or from the decay of neutral mesons like π 0 and η, is an original approach towards the understanding of the dynamics of nuclear reactions and of the behaviour of nuclear matter. The 4 π multidetector TAPS has been constructed for that purpose. Many european laboratories joined their efforts to achieve the equipment. It is therefore also foreseen to use it at various accelerators delivering heavy ions between 10 and 2000 MeV/u and electrons of up to 800 MeV. In the first part of this work, the reasons for the choice of TAPS are described. The second part describes the particular mechanical set up used at GANIL together with its electronics and data acquisition system. In the third part the methods for simulating the response of the detectors are explained. The fourth and last part contains the data analysis of an experiment using the reaction 129 Xe + 197 Au at 44 MeV/u. The first results are very stimulating and demonstrate that TAPS is well suited to the detection of photons in an important hadronic noise. It has also been demonstrated that the detection of very rare events like subthreshold pions, is possible thanks to the excellent performances of TAPS [fr

  5. Evaluation of Harmonic Content from a Tap Transformer Based Grid Connection System for Wind Power

    Directory of Open Access Journals (Sweden)

    S. Apelfröjd

    2013-01-01

    Full Text Available Simulations done in MATLAB/Simulink together with experiments conducted at the Ångströms laboratory are used to evaluate and discuss the total harmonic distortion (THD and total demand distortion (TDD of a tap transformer based grid connection system. The grid connection topology can be used with different turbine and generator topologies and is here applied on a vertical axis wind turbine (VAWT with a permanent magnet synchronous generator (PMSG and its operational scheme. The full variable-speed wind conversion system consists of a diode rectifier, DC link, IGBT inverter, LCL-filter, and tap transformer. The full variable-speed operation is enabled by the use of the different step-up ratios of the tap transformer. In the laboratory study, a full experimental setup of the system was used, a clone of the on-site PMSG driven by a motor was used, and the grid was replaced with a resistive load. With a resistive load, grid harmonics and possible unbalances are removed. The results show a TDD and THD below 5% for the full operating range and harmonic values within the limits set up by IEEE-519. Furthermore, a change in tap, going to a lower step-up ratio, results in a reduction in both THD and TDD for the same output power.

  6. Frankincense production is determined by tree size and tapping frequency and intensity

    NARCIS (Netherlands)

    Eshete, A.; Sterck, F.J.; Bongers, F.

    2012-01-01

    Resin production in trees probably depends on trade-offs within the tree, its environment and on tapping activities. Frankincense, the highly esteemed resin from dry woodland frankincense trees of Boswellia papyrifera is exploited in traditional ways for millennia. New exploitation practices lead to

  7. A Glove for Tapping and Discrete 1D/2D Input

    Science.gov (United States)

    Miller, Sam A.; Smith, Andy; Bahram, Sina; SaintAmant, Robert

    2012-01-01

    This paper describes a glove with which users enter input by tapping fingertips with the thumb or by rubbing the thumb over the palmar surfaces of the middle and index fingers. The glove has been informally tested as the controller for two semi-autonomous robots in a a 3D simulation environment. A preliminary evaluation of the glove s performance is presented.

  8. Secondary steel oxidation on the launder during tapping out of the open-hearth furnace

    Energy Technology Data Exchange (ETDEWEB)

    Oleksa, R P; Yavoiskii, V I; Gorokhov, L S; Vishkarev, A F [Moskovskij Inst. Stali i Splavov (USSR)

    1977-01-01

    An electrochemical method has established an intensive absorption of oxygen through interaction of metal with the surrounding atmosphere on the runner as a melt is being tapped from an open-hearth furnace. During the final ladle deoxidation of steel by effective deoxidizers, the intensity of the secondary oxidation of atmospheric oxygen has no effect upon the quality of the finished metal.

  9. Secondary steel oxidation on the launder during tapping out of the open-hearth furnace

    International Nuclear Information System (INIS)

    Oleksa, R.P.; Yavojskij, V.I.; Gorokhov, L.S.; Vishkarev, A.F.

    1977-01-01

    An electrochemical method has established an intensive absorption of oxygen through interaction of metal with the surrounding atmosphere on the runner as a melt is being tapped from an open-hearth furnace. During the final ladle deoxidation of steel by effective deoxidizers, the intensity of the secondary oxidation of atmospheric oxygen has no effect upon the quality of the finished metal

  10. Lead isotopes in tap water: implications for Pb sources within a municipal water supply system

    International Nuclear Information System (INIS)

    Cheng Zhongqi; Foland, Kenneth A.

    2005-01-01

    Residential tap waters were investigated to examine the feasibility of using isotopic ratios to identify dominant sources of water Pb in the Columbus (Ohio, USA) municipal supply system. Overall, both the concentrations, which are generally low (0.1-28 μg/L), and isotopic compositions of tap water Pb show wide variations. This contrasts with the situation for a limited number of available service lines, which exhibit only a limited Pb-isotope variation but contain Pb of two very different types with one significantly more radiogenic than the other. Most tap water samples in contact with Pb service lines have Pb-isotope ratios that are different from the pipe Pb. Furthermore, the Pb isotope compositions of sequentially drawn samples in the same residence generally are similar, but those from separate residences are different, implying dominant Pb sources from domestic plumbing. A separate pilot study at two residences without Pb service lines shows isotopic similarity between water and solders in each house, further suggesting that the major Pb sources are domestic in these cases and dominated by Pb from solder joints. Although complicated by the broad range of overall Pb-isotope variations observed and limited by sample availability, the results suggest that Pb isotopes can be used effectively to constrain the sources of Pb in tap waters, especially for individual houses where multiple source candidates can be identified

  11. Determination of calcium in Mashhad city tap water by flame atomic absorption spectrometry

    International Nuclear Information System (INIS)

    Mashhadian, N.V.

    2012-01-01

    Summary: Calcium in drinking water is one of the sources of calcium that may contribute significantly to the daily calcium intake. In this study, the samples of tap water were randomly taken from five zones of Mashhad city. Calcium concentration was determined by flame atomic absorption spectrometry (FAAS) technique. The precision of the method was evaluated. The CV% of 6 replicate determinations at 5 macro g/ml Ca was 4.2 in one day and 4.5, among 6 consecutive days. The recovery of spiked samples (98.7%) also showed that the proposed method is reliable for the determination of amounts of calcium in water samples. The mean of calcium in tap water in the city of Mashhad was 52.61+-12.91 (SD) macro g/ml. At present, the amount of calcium in Mashhad tap waters is within the national standard. However, due to the climate and environmental changes, determination of calcium in tap water of Mashhad in different seasons is recommended. (author)

  12. A tapping device for recording and quantitative characterization of rhythmic/auditory sequences.

    Science.gov (United States)

    Piazza, Caterina; Cesareo, Ambra; Caccia, Martina; Reni, Gianluigi; Lorusso, Maria L

    2017-07-01

    The processing of auditory stimuli is essential for the correct perception of language and deficits in this ability are often related to the presence or development of language disorders. The motor imitation (e.g. tapping or beating) of rhythmic sequences can be a very sensitive correlate of deficits in auditory processing. Thus, the study of the tapping performance, with the investigation of both temporal and intensity information, might be very useful. The present work is aimed at the development and preliminary testing of a tapping device to be used for the imitation and/or the production of rhythmic sequences, allowing the recording of both tapping duration and intensity. The device is essentially made up of a Force Sensing Resistor and an Arduino UNO board. It was validated using different sampling frequencies (f s ) in a group of 10 young healthy adults investigating its efficacy in terms of touch and intensity detection by means of two testing procedures. Results demonstrated a good performance of the device when programmed with fs equal to 50 and 100Hz. Moreover, both temporal and intensity parameters were extracted, thus supporting the potential use of the device for the analysis of the imitation or production of rhythmic sequences. This work represents a first step for the development of a useful, low cost tool to support the diagnosis, training and rehabilitation of language disorders.

  13. The effect of tapping for frankincense on sexual reproduction in Boswellia papyrifera

    NARCIS (Netherlands)

    Rijkers, A.J.M.; Ogbazghi, W.; Wessel, M.; Bongers, F.J.J.M.

    2006-01-01

    1. In the Horn of Africa, frankincense (an aromatic hardened wood resin) is obtained by tapping Boswellia papyrifera. World-wide, frankincense is of great economic and social importance as an important element of incense and perfumes. The production is declining as a result of poor natural

  14. Tests of some methods to remove I-131 from contaminated tap water

    International Nuclear Information System (INIS)

    Tagami, Keiko; Uchida, Shigeo

    2011-01-01

    Following the Fukushima Daiichi Nuclear Power Plant accident, iodine-131 concentrations in tap water higher than 100 Bq L"-"1 were reported by several local governments in the Kanto Plain in March 2011. To remove iodine-131 from tap water, five methods were tested in this study, that is, (1) boiling, (2) adding charcoals from oak or bamboo, (3) activated charcoals, (4) water purifiers, and (5) reverse osmosis (RO) treatments. Boiling was shown to be not effective in removing iodine-131 from tap water; indeed even higher concentrations may result from the liquid-volume reduction accompanying this process. Adding charcoals and activated charcoal treatment could not remove iodine-131, because no reduction of iodine-131 was observed in tap water samples after these treatments. Only limited effect was found with water purifiers with first several portions; no effect was expected with further water treatment. On the other hand, the RO showed high iodine-131 removal percentage of more than 95%, although the method needs about 5-10 L water to obtain 1 L of RO treated water. (author)

  15. Thermal destratification in small standard solar tanks due to mixing during tapping

    DEFF Research Database (Denmark)

    Andersen, Elsa; Furbo, Simon

    1999-01-01

    The aim of the project is to investigate the thermal destratification in small standard solar tanks due to mixing during tapping. Three different cold water inlet designs are tested. A model of the tested solar tank is verified. Based on the measurements and the calculations it is elucidated how...

  16. Early-Stage Chunking of Finger Tapping Sequences by Persons Who Stutter and Fluent Speakers

    Science.gov (United States)

    Smits-Bandstra, Sarah; De Nil, Luc F.

    2013-01-01

    This research note explored the hypothesis that chunking differences underlie the slow finger-tap sequencing performance reported in the literature for persons who stutter (PWS) relative to fluent speakers (PNS). Early-stage chunking was defined as an immediate and spontaneous tendency to organize a long sequence into pauses, for motor planning,…

  17. Analysis and Comparison of Magnetic Structures in a Tapped Boost Converter for LED Applications

    DEFF Research Database (Denmark)

    Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    This paper presents an an alysis and comparison of magnetics structures in a tapped boost converter for LED applications. The magnetic structure is a coupled inductor which is analyzed in a conventional wire-wound core as well as in a planar structure for different interleaving winding arrangements...

  18. On design and evaluation of tapped-delay neural network architectures

    DEFF Research Database (Denmark)

    Svarer, Claus; Hansen, Lars Kai; Larsen, Jan

    1993-01-01

    Pruning and evaluation of tapped-delay neural networks for the sunspot benchmark series are addressed. It is shown that the generalization ability of the networks can be improved by pruning using the optimal brain damage method of Le Cun, Denker and Solla. A stop criterion for the pruning algorithm...

  19. A Tapped-Inductor Buck-Boost Converter for a Dielectric ElectroActive Polymer Generator

    DEFF Research Database (Denmark)

    Dimopoulos, Emmanouil; Munk-Nielsen, Stig

    2014-01-01

    of commercially-available, high-efficient, high-voltage, low-power semiconductor devices. In this paper, a high-efficient bidirectional tapped-inductor buck-boost converter, addressing high step-up and high step-down voltage conversion ratios, is proposed for energy harvesting applications based on DEAP...

  20. Analysis of dynamic cantilever behavior in tapping mode atomic force microscopy.

    Science.gov (United States)

    Deng, Wenqi; Zhang, Guang-Ming; Murphy, Mark F; Lilley, Francis; Harvey, David M; Burton, David R

    2015-10-01

    Tapping mode atomic force microscopy (AFM) provides phase images in addition to height and amplitude images. Although the behavior of tapping mode AFM has been investigated using mathematical modeling, comprehensive understanding of the behavior of tapping mode AFM still poses a significant challenge to the AFM community, involving issues such as the correct interpretation of the phase images. In this paper, the cantilever's dynamic behavior in tapping mode AFM is studied through a three dimensional finite element method. The cantilever's dynamic displacement responses are firstly obtained via simulation under different tip-sample separations, and for different tip-sample interaction forces, such as elastic force, adhesion force, viscosity force, and the van der Waals force, which correspond to the cantilever's action upon various different representative computer-generated test samples. Simulated results show that the dynamic cantilever displacement response can be divided into three zones: a free vibration zone, a transition zone, and a contact vibration zone. Phase trajectory, phase shift, transition time, pseudo stable amplitude, and frequency changes are then analyzed from the dynamic displacement responses that are obtained. Finally, experiments are carried out on a real AFM system to support the findings of the simulations. © 2015 Wiley Periodicals, Inc.

  1. Analysis of the Difference of Radon Concentration between Water Treatment Plant and Tap water in house

    International Nuclear Information System (INIS)

    Seo, Jeongil; Yoo, Donghan; Kim, Heereyoung

    2013-01-01

    As importance for the health, measurements and analysis about radon is active recently. Especially, radon concentration measurement about underground water which people drink was been carried out by the environment organizations in Korea and has been hot-issued because of the high radon concentration in water source. In present study, the difference of radon concentration among water source, water treatment plant and tap water in house is analyzed. It makes sense that the radon concentration in water treatment plant can represent the radon concentration in the tap water. Through the above experiments, the difference of the radon concentration between water treatment plant and tap water in house is figured out. It contributes to confirm more specific basis for estimating the annual radon exposure for the public. With further experiments and analysis, it is thought that it will be used as tool to assess more qualitatively for the radon concentration in tap water. Finally, this Fundamental approach will help in making new regulations about radon

  2. Tapping mode SPM local oxidation nanolithography with sub-10 nm resolution

    International Nuclear Information System (INIS)

    Nishimura, S; Ogino, T; Shirakashi, J; Takemura, Y

    2008-01-01

    Tapping mode SPM local oxidation nanolithography with sub-10 nm resolution is investigated by optimizing the applied bias voltage (V), scanning speed (S) and the oscillation amplitude of the cantilever (A). We fabricated Si oxide wires with an average width of 9.8 nm (V = 17.5 V, S 250 nm/s, A = 292 nm). In SPM local oxidation with tapping mode operation, it is possible to decrease the size of the water meniscus by enhancing the oscillation amplitude of cantilever. Hence, it seems that the water meniscus with sub-10 nm dimensions could be formed by precisely optimizing the oxidation conditions. Moreover, we quantitatively explain the size (width and height) of Si oxide wires with a model based on the oxidation ratio, which is defined as the oxidation time divided by the period of the cantilever oscillation. The model allows us to understand the mechanism of local oxidation in tapping mode operation with amplitude modulation. The results imply that the sub-10 nm resolution could be achieved using tapping mode SPM local oxidation technique with the optimization of the cantilever dynamics

  3. Fabrication of tungsten probe for hard tapping operation in atomic force microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Han, Guebum, E-mail: hanguebum@live.co.kr [Department of Physics and Optical Engineering, Rose-Hulman Institute of Technology, 5500 Wabash Avenue, Terre Haute, Indiana 47803 (United States); Department of Mechanical Design and Robot Engineering, Seoul National University of Science and Technology, 232 Gongneung-ro, Nowon-gu, Seoul 139-743 (Korea, Republic of); Ahn, Hyo-Sok, E-mail: hsahn@seoultech.ac.kr [Manufacturing Systems and Design Engineering Programme, Seoul National University of Science & Technology, 232 Gongneung-ro, Nowon-gu, Seoul 139-743 (Korea, Republic of)

    2016-02-15

    We propose a method of producing a tungsten probe with high stiffness for atomic force microscopy (AFM) in order to acquire enhanced phase contrast images and efficiently perform lithography. A tungsten probe with a tip radius between 20 nm and 50 nm was fabricated using electrochemical etching optimized by applying pulse waves at different voltages. The spring constant of the tungsten probe was determined by finite element analysis (FEA), and its applicability as an AFM probe was evaluated by obtaining topography and phase contrast images of a Si wafer sample partly coated with Au. Enhanced hard tapping performance of the tungsten probe compared with a commercial Si probe was confirmed by conducting hard tapping tests at five different oscillation amplitudes on single layer graphene grown by chemical vapor deposition (CVD). To analyze the damaged graphene sample, the test areas were investigated using tip-enhanced Raman spectroscopy (TERS). The test results demonstrate that the tungsten probe with high stiffness was capable of inducing sufficient elastic and plastic deformation to enable obtaining enhanced phase contrast images and performing lithography, respectively. - Highlights: • We propose a method of producing highly stiff tungsten probes for hard tapping AFM. • Spring constant of tungsten probe is determined by finite element method. • Enhanced hard tapping performance is confirmed. • Tip-enhanced Raman spectroscopy is used to identify damage to graphene.

  4. Fabrication of tungsten probe for hard tapping operation in atomic force microscopy

    International Nuclear Information System (INIS)

    Han, Guebum; Ahn, Hyo-Sok

    2016-01-01

    We propose a method of producing a tungsten probe with high stiffness for atomic force microscopy (AFM) in order to acquire enhanced phase contrast images and efficiently perform lithography. A tungsten probe with a tip radius between 20 nm and 50 nm was fabricated using electrochemical etching optimized by applying pulse waves at different voltages. The spring constant of the tungsten probe was determined by finite element analysis (FEA), and its applicability as an AFM probe was evaluated by obtaining topography and phase contrast images of a Si wafer sample partly coated with Au. Enhanced hard tapping performance of the tungsten probe compared with a commercial Si probe was confirmed by conducting hard tapping tests at five different oscillation amplitudes on single layer graphene grown by chemical vapor deposition (CVD). To analyze the damaged graphene sample, the test areas were investigated using tip-enhanced Raman spectroscopy (TERS). The test results demonstrate that the tungsten probe with high stiffness was capable of inducing sufficient elastic and plastic deformation to enable obtaining enhanced phase contrast images and performing lithography, respectively. - Highlights: • We propose a method of producing highly stiff tungsten probes for hard tapping AFM. • Spring constant of tungsten probe is determined by finite element method. • Enhanced hard tapping performance is confirmed. • Tip-enhanced Raman spectroscopy is used to identify damage to graphene.

  5. Response of TAPS to monochromatic photons with energies between 45 and 790 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Gabler, A.R. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Doering, W. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Fuchs, M. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Krusche, B. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Metag, V. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Novotny, R. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Roebig-Landau, M. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Stroeher, H. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Tries, V. (II. Physikalisches Institut, Universitaet Giessen, D-35392 Giessen (Germany)); Molenaar, C. (Kernfysisch Versneller Instituut, Groningen (Netherlands)); Loehner, H. (Kernfysisch Versneller Instituut, Groningen (Netherlands)); Van Pol, J.H

    1994-07-15

    The Two Arm Photon Spectrometer TAPS - comprising 384 plastic-BaF[sub 2] scintillator telescopes - was tested with monochromatic photons in the energy range between 45 and 790 MeV. The energy resolution for a collimated photon beam hitting the central detector module was determined to [sigma]/E=0.59%xE[sup -1/2][sub [gamma

  6. The presence and growth of Legionella species in thermostatic shower mixer taps: an exploratory field study

    NARCIS (Netherlands)

    Joost van Hoof; P.W.J.J. van der Wielen; E. van der Blom; O.W.W. Nuijten; L. Hornstra

    2014-01-01

    Legislation in the Netherlands requires routine analysis of drinking water samples for cultivable Legionella species from high-priority installations. A field study was conducted to investigate the presence of Legionella species in thermostatic shower mixer taps. Water samples and the interior of

  7. Analysis of UV filters in tap water and other clean waters in Spain.

    Science.gov (United States)

    Díaz-Cruz, M Silvia; Gago-Ferrero, Pablo; Llorca, Marta; Barceló, Damià

    2012-03-01

    The present paper describes the development of a method for the simultaneous determination of five hormonally active UV filters namely benzophenone-3 (BP3), 3-(4-methylbenzylidene) camphor (4MBC), 2-ethylhexyl 4-(dimethylamino) benzoate (OD-PABA), 2-ethylhexyl 4-methoxycinnamate (EHMC) and octocrylene (OC) by means of solid-phase extraction and gas chromatography-electron impact ionization-mass spectrometry. Under optimized conditions, this methodology achieved low method limits of detection (needed for clean waters, especially drinking water analysis), between 0.02 and 8.42 ng/L, and quantitative recovery rates higher than 73% in all cases. Inter- and intraday precision for all compounds were lower than 7% and 11%, respectively. The optimized methodology was applied to perform the first survey of UV absorbing compounds in tap water from the metropolitan area and the city of Barcelona (Catalonia, Spain). In addition, other types of clean water matrices (mineral bottled water, well water and tap water treated with an ion-exchange resin) were investigated as well. Results evidenced that all the UV filters investigated were detected in the water samples analyzed. The compounds most frequently found were EHMC and OC. Maximum concentrations reached in tap water were 290 (BP3), 35 (4MBC), 110 (OD-PABA), 260 (EHMC), and 170 ng/L (OC). This study constitutes the first evidence of the presence of UV filter residues in tap water in Europe.

  8. SSFSE sequence functional MRI of the human cervical spinal cord with complex finger tapping

    International Nuclear Information System (INIS)

    Xie Chuhai; Kong Kangmei; Guan Jitian; Chen Yexi; He Jiankang; Qi Weili; Wang Xinjia; Shen Zhiwei; Wu Renhua

    2009-01-01

    Purpose: Functional MR imaging of the human cervical spinal cord was carried out on volunteers during alternated rest and a complex finger tapping task, in order to detect image intensity changes arising from neuronal activity. Methods: Functional MR imaging data using single-shot fast spin-echo sequence (SSFSE) with echo time 42.4 ms on a 1.5 T GE Clinical System were acquired in eight subjects performing a complex finger tapping task. Cervical spinal cord activation was measured both in the sagittal and transverse imaging planes. Postprocessing was performed by AFNI (Analysis of Functional Neuroimages) software system. Results: Intensity changes (5.5-7.6%) were correlated with the time course of stimulation and were consistently detected in both sagittal and transverse imaging planes of the cervical spinal cord. The activated regions localized to the ipsilateral side of the spinal cord in agreement with the neural anatomy. Conclusion: Functional MR imaging signals can be reliably detected with finger tapping activity in the human cervical spinal cord using a SSFSE sequence with 42.4 ms echo time. The anatomic location of neural activity correlates with the muscles used in the finger tapping task.

  9. Mapping Electrostatic Forces Using Higher Harmonics Tapping Mode Atomic Force Microscopy in Liquid

    NARCIS (Netherlands)

    van Noort, S.J.T.; Willemsen, O.H.; van der Werf, Kees; de Grooth, B.G.; Greve, Jan

    1999-01-01

    A simple model of a damped, harmonic oscillator is used to describe the motion of an atomic force microscope cantilever tapping in fluid. By use of experimentally obtained parameters, excellent agreement is found between theory and experimental results. From the model we estimate that the force

  10. Using TAPS Focused Assessments as Part of Our Teacher Assessment Approach

    Science.gov (United States)

    Barber, Kerry-Anne

    2018-01-01

    As the Science Co-ordinator at St Paul's RC Primary School, the author has been involved in producing and trialling resources for the Teacher Assessment in Primary Science (TAPS) project over the last four years. This article explains how St Paul's has used the Focused Assessments (FAs). The author has always tried to promote enquiry-based…

  11. Analisa Perbaikan Profil Tegangan Sistem Tenaga Listrik Sumbar Menggunakan Kapasitor Bank dan Tap Transformator

    Directory of Open Access Journals (Sweden)

    Akbar Abadi

    2015-09-01

    Full Text Available Voltage stability evaluation is needed to get the information of electrical power distribution system performance. Power flow calculation is used to determine the important parameters of power system in a steady state. An electric power system must have voltage value that does not exceed the limits of tolerance and the power loss as well as small. The improvement of voltage profile can be done by using voltage-control equipments, such as capacitor banks and transformer tap. Through simulation using the PowerWorld simulator, the value and location of capacitor banks and transformers tap will obtained in order to improve system performace. Sumbar electrical system was used in this study. From the simulation results, for the initial condition of the system, there are several buses that have voltage drop with total system losses 14.4 MW. After capacitor added, the system voltage has increased significantly so that no one passed the value of tolerance and the losses in the system down to 14.1 MW. As for setting the ratio of tap transformer, voltage system did not change so much, except on the secondary side of the transformer bus arranged with system losses almost the same that equal to 14.4 MW. For the case of the addition of the capacitor and transformer tap settings in the same time, the voltage drop no longer exceeds 5% and the total system losses decreased to 13.9 MW.

  12. Voltage Management in Unbalanced Low Voltage Networks Using a Decoupled Phase-Tap-Changer Transformer

    DEFF Research Database (Denmark)

    Coppo, Massimiliano; Turri, Roberto; Marinelli, Mattia

    2014-01-01

    The paper studies a medium voltage-low voltage transformer with a decoupled on load tap changer capability on each phase. The overall objective is the evaluation of the potential benefits on a low voltage network of such possibility. A realistic Danish low voltage network is used for the analysis...

  13. Relationship between the incidence infection stones and the magnesium-calcium ratio of tap water.

    Science.gov (United States)

    Kohri, K; Ishikawa, Y; Iguchi, M; Kurita, T; Okada, Y; Yoshida, O

    1993-01-01

    In a previous study we showed that the magnesium-calcium ratio of tap water is negatively correlated with the incidence of calcium-containing urinary stones. In this study we examined the relationship between the incidence of struvite stones, water hardness and the regional geological features on the basis of our previous study and an epidemiological study of urolithiasis performed in Japan. The magnesium-calcium ratio of tap water was found to correlate positively with the incidence of struvite stones. The tap water magnesium-calcium ratio was high in regions of basalt and sedimentary rock and was low in granite and limestone areas. The incidence of struvite stones in the regions of basalt and sedimentary rock was higher than that in the granite and limestone areas. Thus, this study suggested that the incidence of struvite stones is related to the magnesium-calcium ratio of tap water and to the regional geology, as is the case for calcium-containing stones.

  14. Perfluoroalkyl acids (PFAAs) in the Pra and Kakum River basins and associated tap water in Ghana.

    Science.gov (United States)

    Essumang, David K; Eshun, Albert; Hogarh, Jonathan N; Bentum, John K; Adjei, Joseph K; Negishi, Junya; Nakamichi, Shihori; Habibullah-Al-Mamun, Md; Masunaga, Shigeki

    2017-02-01

    Perfluoroalkyl acids (PFAAs) are persistent environmental pollutants that have been detected in various media including human serum. Due to concerns regarding their bioaccumulation and possible negative health effects, an understanding of routes of human exposure is necessary. PFAAs are recalcitrant in many water treatment processes, making drinking water a potential source of human exposure. This study presents the first report on contamination from PFAAs in river and drinking water in Ghana. The targeted PFAAs were perfluoroalkyl carboxylic acids (PFCAs) with C 4-14 carbon chain and perfluoroalkane sulphonic acids (PFSAs) with C 6, 8, 10 . Five PFAA congeners - PFOA, PFOS, PFHxA, PFDA and PFPeA - were commonly detected in river and tap water. The mean concentrations of ∑PFAAs in the Kakum and Pra Rivers were 281 and 398ng/L, while tap water (supplied from the treatment of water from those rivers) contained concentrations of 197 and 200ng/L, respectively. PFOA and PFOS constituted about 99% of the ∑PFAAs. The risk quotient (RQ) attributed to drinking of tap water was estimated at 1.01 and 1.74 for PFOA and PFOS, respectively. For a country that has not produced these compounds, the RQs were unexpectedly high, raising concerns particularly about contamination from such emerging pollutants in local water sources. The study revealed limitations of local tap water treatment in getting rid of these emerging pollutants. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Effect of occlusal contact stability on the jaw closing point during tapping movements.

    Science.gov (United States)

    Nishigawa, Keisuke; Suzuki, Yoshitake; Ishikawa, Teruaki; Bando, Eiichi

    2012-04-01

    We studied the relationship between tapping point reproducibility and stability of occlusal contacts at maximum intercuspation. Tapping movements of 12 adult volunteers who had dentition with natural teeth were recorded, and distances between the tapping point (TP) and the intercuspal position (ICP) at the incisal point were calculated. Occlusal contacts at the ICP of individual subjects were also evaluated with black-colored silicone impression material. The correlation between TP-ICP distance and occlusal contact stability was studied. TP-ICP distance exhibited negative correlations with the total number of teeth showing occlusal contact at the ICP. Standard deviations of TP-ICP distance also negatively correlated with the extension of occlusal contact area over dentition. This finding indicates that occlusal contacts at the ICP affect the kinematic behavior of tapping movements. The results of this study also suggest that jaw movement data may provide useful clinical information for the evaluation of occlusal contact at ICP. Copyright © 2011 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  16. Being Hipped to Their Hop: Tapping into Young Minds through Hip Hop Play

    Science.gov (United States)

    Broughton, Anthony

    2017-01-01

    Adults gain a wealth of knowledge from listening to the voices of children through intentional observations and interactions [Owocki, G., and Y. M. Goodman. 2002. "Kidwatching: Documenting Children's Literacy Development." Portsmouth: Heinemann]. Hip Hop play may provide optimal opportunities for teachers to tap into the young minds of…

  17. Functional Imaging of Human Vestibular Cortex Activity Elicited by Skull Tap and Auditory Tone Burst

    Science.gov (United States)

    Noohi, F.; Kinnaird, C.; Wood, S.; Bloomberg, J.; Mulavara, A.; Seidler, R.

    2016-01-01

    The current study characterizes brain activation in response to two modes of vestibular stimulation: skull tap and auditory tone burst. The auditory tone burst has been used in previous studies to elicit either the vestibulo-spinal reflex (saccular-mediated colic Vestibular Evoked Myogenic Potentials (cVEMP)), or the ocular muscle response (utricle-mediated ocular VEMP (oVEMP)). Some researchers have reported that air-conducted skull tap elicits both saccular and utricle-mediated VEMPs, while being faster and less irritating for the subjects. However, it is not clear whether the skull tap and auditory tone burst elicit the same pattern of cortical activity. Both forms of stimulation target the otolith response, which provides a measurement of vestibular function independent from semicircular canals. This is of high importance for studying otolith-specific deficits, including gait and balance problems that astronauts experience upon returning to earth. Previous imaging studies have documented activity in the anterior and posterior insula, superior temporal gyrus, inferior parietal lobule, inferior frontal gyrus, and the anterior cingulate cortex in response to different modes of vestibular stimulation. Here we hypothesized that skull taps elicit similar patterns of cortical activity as the auditory tone bursts, and previous vestibular imaging studies. Subjects wore bilateral MR compatible skull tappers and headphones inside the 3T GE scanner, while lying in the supine position, with eyes closed. Subjects received both forms of the stimulation in a counterbalanced fashion. Pneumatically powered skull tappers were placed bilaterally on the cheekbones. The vibration of the cheekbone was transmitted to the vestibular system, resulting in the vestibular cortical response. Auditory tone bursts were also delivered for comparison. To validate our stimulation method, we measured the ocular VEMP outside of the scanner. This measurement showed that both skull tap and auditory

  18. Temporal hemodynamic classification of two hands tapping using functional near-infrared spectroscopy.

    Science.gov (United States)

    Thanh Hai, Nguyen; Cuong, Ngo Q; Dang Khoa, Truong Q; Van Toi, Vo

    2013-01-01

    In recent decades, a lot of achievements have been obtained in imaging and cognitive neuroscience of human brain. Brain's activities can be shown by a number of different kinds of non-invasive technologies, such as: Near-Infrared Spectroscopy (NIRS), Magnetic Resonance Imaging (MRI), and ElectroEncephaloGraphy (EEG; Wolpaw et al., 2002; Weiskopf et al., 2004; Blankertz et al., 2006). NIRS has become the convenient technology for experimental brain purposes. The change of oxygenation changes (oxy-Hb) along task period depending on location of channel on the cortex has been studied: sustained activation in the motor cortex, transient activation during the initial segments in the somatosensory cortex, and accumulating activation in the frontal lobe (Gentili et al., 2010). Oxy-Hb concentration at the aforementioned sites in the brain can also be used as a predictive factor allows prediction of subject's investigation behavior with a considerable degree of precision (Shimokawa et al., 2009). In this paper, a study of recognition algorithm will be described for recognition whether one taps the left hand (LH) or the right hand (RH). Data with noises and artifacts collected from a multi-channel system will be pre-processed using a Savitzky-Golay filter for getting more smoothly data. Characteristics of the filtered signals during LH and RH tapping process will be extracted using a polynomial regression (PR) algorithm. Coefficients of the polynomial, which correspond to Oxygen-Hemoglobin (Oxy-Hb) concentration, will be applied for the recognition models of hand tapping. Support Vector Machines (SVM) will be applied to validate the obtained coefficient data for hand tapping recognition. In addition, for the objective of comparison, Artificial Neural Networks (ANNs) was also applied to recognize hand tapping side with the same principle. Experimental results have been done many trials on three subjects to illustrate the effectiveness of the proposed method.

  19. Finger tapping analysis in patients with Parkinson's disease and atypical parkinsonism.

    Science.gov (United States)

    Djurić-Jovičić, Milica; Petrović, Igor; Ječmenica-Lukić, Milica; Radovanović, Saša; Dragašević-Mišković, Nataša; Belić, Minja; Miler-Jerković, Vera; Popović, Mirjana B; Kostić, Vladimir S

    2016-08-01

    The goal of this study was to investigate repetitive finger tapping patterns in patients with Parkinson's disease (PD), progressive supranuclear palsy-Richardson syndrome (PSP-R), or multiple system atrophy of parkinsonian type (MSA-P). The finger tapping performance was objectively assessed in PD (n=13), PSP-R (n=15), and MSA-P (n=14) patients and matched healthy controls (HC; n=14), using miniature inertial sensors positioned on the thumb and index finger, providing spatio-temporal kinematic parameters. The main finding was the lack or only minimal progressive reduction in amplitude during the finger tapping in PSP-R patients, similar to HC, but significantly different from the sequence effect (progressive decrement) in both PD and MSA-P patients. The mean negative amplitude slope of -0.12°/cycle revealed less progression of amplitude decrement even in comparison to HC (-0.21°/cycle, p=0.032), and particularly from PD (-0.56°/cycle, p=0.001), and MSA-P patients (-1.48°/cycle, p=0.003). No significant differences were found in the average finger separation amplitudes between PD, PSP-R and MSA-P patients (pmsa-pd=0.726, pmsa-psp=0.363, ppsp-pd=0.726). The lack of clinically significant sequence effect during finger tapping differentiated PSP-R from both PD and MSA-P patients, and might be specific for PSP-R. The finger tapping kinematic parameter of amplitude slope may be a neurophysiological marker able to differentiate particular forms of parkinsonism. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Performance monitoring of zircaloy-4 square fuel channels at TAPS-1 and 2

    International Nuclear Information System (INIS)

    Akhtar, J.; Ramu, A.; Anilkumar, K.R.; Sharma, B.L.; Bhattacharjee, S.; Ramamurty, U.; Srivastava, S.P.; Prasad, P.N.; Anantharaman, K.

    2006-01-01

    Tarapur Atomic Power Station is a twin unit Boiling Water Reactors. The initial rated capacity of each unit was 210 MWe. Subsequently due to Secondary Steam Generator tube leak problem, the units were de-rated to 160 MWe in the year 1984-85. The station has completed 36 years of successful commercial operation. TAPS reactor fuel channels are made of Zircaloy-4, material. These are used along with 6x6 array nuclear fuel assemblies. The fuel channels need to be discharged once it reaches an optimum exposure limit and based on the surveillance programme, which monitors the channels performance. NFC has indigenously developed fuel channels for TAPS and these are at various stages of exposure in both the reactor cores. The performance review of these channels was carried out by the experts from TAPS-Site, NPCIL-ED and RED, BARC. The two major factors, which affect fuel channels performance, are (a) Bulge and (b) Bow. The phenomenon of longitudinal bow occurs due to the neutron flux gradient across the channels faces. Studies made on this subject by General Electric (GE) indicated that this channel deflection occurs at a slow rate. Therefore, fuel channels surveillance programme is essential to check the irradiated fuel channels performance in order to replace the fuel channels once it reaches the optimum exposure limit. To estimate the useful life of irradiated fuel channels, channel deflection/bulge measurement inspection system and methodology was developed jointly by TAPS and Centre for Design and manufacture (CDM), BARC. This system was successfully deployed at TAPS. This paper briefly describes the developmental efforts made by Nuclear Fuel Complex (NFC), Hyderabad, NPCIL-Fuel Group, Engg.Directorate, RED/BARC, CDM/BARC. (author)

  1. Uncovering beat deafness: detecting rhythm disorders with synchronized finger tapping and perceptual timing tasks.

    Science.gov (United States)

    Dalla Bella, Simone; Sowiński, Jakub

    2015-03-16

    A set of behavioral tasks for assessing perceptual and sensorimotor timing abilities in the general population (i.e., non-musicians) is presented here with the goal of uncovering rhythm disorders, such as beat deafness. Beat deafness is characterized by poor performance in perceiving durations in auditory rhythmic patterns or poor synchronization of movement with auditory rhythms (e.g., with musical beats). These tasks include the synchronization of finger tapping to the beat of simple and complex auditory stimuli and the detection of rhythmic irregularities (anisochrony detection task) embedded in the same stimuli. These tests, which are easy to administer, include an assessment of both perceptual and sensorimotor timing abilities under different conditions (e.g., beat rates and types of auditory material) and are based on the same auditory stimuli, ranging from a simple metronome to a complex musical excerpt. The analysis of synchronized tapping data is performed with circular statistics, which provide reliable measures of synchronization accuracy (e.g., the difference between the timing of the taps and the timing of the pacing stimuli) and consistency. Circular statistics on tapping data are particularly well-suited for detecting individual differences in the general population. Synchronized tapping and anisochrony detection are sensitive measures for identifying profiles of rhythm disorders and have been used with success to uncover cases of poor synchronization with spared perceptual timing. This systematic assessment of perceptual and sensorimotor timing can be extended to populations of patients with brain damage, neurodegenerative diseases (e.g., Parkinson's disease), and developmental disorders (e.g., Attention Deficit Hyperactivity Disorder).

  2. Temporal hemodynamic classification of two hands tapping using functional near—infrared spectroscopy

    Science.gov (United States)

    Thanh Hai, Nguyen; Cuong, Ngo Q.; Dang Khoa, Truong Q.; Van Toi, Vo

    2013-01-01

    In recent decades, a lot of achievements have been obtained in imaging and cognitive neuroscience of human brain. Brain's activities can be shown by a number of different kinds of non-invasive technologies, such as: Near-Infrared Spectroscopy (NIRS), Magnetic Resonance Imaging (MRI), and ElectroEncephaloGraphy (EEG; Wolpaw et al., 2002; Weiskopf et al., 2004; Blankertz et al., 2006). NIRS has become the convenient technology for experimental brain purposes. The change of oxygenation changes (oxy-Hb) along task period depending on location of channel on the cortex has been studied: sustained activation in the motor cortex, transient activation during the initial segments in the somatosensory cortex, and accumulating activation in the frontal lobe (Gentili et al., 2010). Oxy-Hb concentration at the aforementioned sites in the brain can also be used as a predictive factor allows prediction of subject's investigation behavior with a considerable degree of precision (Shimokawa et al., 2009). In this paper, a study of recognition algorithm will be described for recognition whether one taps the left hand (LH) or the right hand (RH). Data with noises and artifacts collected from a multi-channel system will be pre-processed using a Savitzky–Golay filter for getting more smoothly data. Characteristics of the filtered signals during LH and RH tapping process will be extracted using a polynomial regression (PR) algorithm. Coefficients of the polynomial, which correspond to Oxygen-Hemoglobin (Oxy-Hb) concentration, will be applied for the recognition models of hand tapping. Support Vector Machines (SVM) will be applied to validate the obtained coefficient data for hand tapping recognition. In addition, for the objective of comparison, Artificial Neural Networks (ANNs) was also applied to recognize hand tapping side with the same principle. Experimental results have been done many trials on three subjects to illustrate the effectiveness of the proposed method. PMID:24032008

  3. An fMRI study of finger tapping in children and adults.

    Science.gov (United States)

    Turesky, Ted K; Olulade, Olumide A; Luetje, Megan M; Eden, Guinevere F

    2018-04-02

    Functional brain imaging studies have characterized the neural bases of voluntary movement for finger tapping in adults, but equivalent information for children is lacking. When contrasted to adults, one would expect children to have relatively greater activation, reflecting compensation for an underdeveloped motor system combined with less experience in the execution of voluntary movement. To test this hypothesis, we acquired functional magnetic resonance imaging (fMRI) data on 17 healthy right-handed children (7.48 ± 0.66 years) and 15 adults (24.9 ± 2.9 years) while they performed an irregularly paced finger-tapping task in response to a visual cue (left- and right-hand examined separately). Whole-brain within-group analyses revealed that finger tapping in either age group and for either hand activated contralateral SM1, SMA, ipsilateral anterior cerebellum, and occipital cortices. We used an ANOVA factorial design to test for main effects of Age Group (children vs adults), Hand (left vs. right), and their interactions. For main effects of Age Group, children showed relatively greater activity in left SM1 (extending into bilateral SMA), and, surprisingly, adults exhibited relatively greater activity in right pre-SMA/SMA (extending into left pre-SMA/SMA), right lateral globus pallidus, left putamen, and right anterior cerebellum. The interaction of Age Group × Hand revealed that while both groups activated right SM1 during left finger tapping and exhibited signal decreases (i.e., below fixation baseline) during right finger tapping, both these responses were attenuated in children relative to adults. These data provide an important foundation by which to study children with motor disorders. © 2018 Wiley Periodicals, Inc.

  4. Finger tapping and verbal fluency post-tap test improvement in INPH: its value in differential diagnosis and shunt-treatment outcomes prognosis.

    Science.gov (United States)

    Liouta, Evangelia; Gatzonis, Stylianos; Kalamatianos, Theodosis; Kalyvas, Aristotelis; Koutsarnakis, Christos; Liakos, Faidon; Anagnostopoulos, Christos; Komaitis, Spyridon; Giakoumettis, Dimitris; Stranjalis, George

    2017-12-01

    Idiopathic normal pressure hydrocephalus (INPH) diagnosis is challenging as it can be mimicked by other neurological conditions, such as neurodegenerative dementia and motor syndromes. Additionally, outcomes after lumbar puncture (LP) tap test and shunt treatment may vary due to the lack of a common protocol in INPH assessment. The present study aimed to assess whether a post-LP test amelioration of frontal cognitive dysfunctions, characterizing this syndrome, can differentiate INPH from similar neurological conditions and whether this improvement can predict INPH post-shunt outcomes. Seventy-one consecutive patients referred for INPH suspicion and LP testing, were enrolled. According to the consensus guidelines criteria, 29 patients were diagnosed as INPH and 42 were assigned an alternative diagnosis (INPH-like group) after reviewing clinical, neuropsychological and imaging data, and before LP results. A comprehensive neuropsychological assessment for frontal executive, upper extremity fine motor functions, aphasias, apraxias, agnosias and gait evaluation were administered at baseline. Executive, fine motor functions and gait were re-examined post-LP test in all patients and post-shunt placement in INPH patients. Of the INPH patients, 86.2% showed cognitive amelioration in the post-LP test; in addition, all but one (97%) presented with neurocognitive and gait improvement post-shunt. Verbal phonological fluency and finger tapping task post-LP improvement predicted positive clinical outcome post-shunt. None of the INPH-like group presented with neurocognitive improvement post-LP. Post-LP amelioration of verbal fluency and finger tapping deficits can differentiate INPH from similar disorders and predict positive post-shunt clinical outcome in INPH. This becomes of great importance when gait assessment is difficult to perform in clinical practice.

  5. The TApIR experiment. IR absorption spectra of liquid hydrogen isotopologues; Das TApIR Experiment IR-Absorptionsspektren fluessiger Wasserstoffisotopologe

    Energy Technology Data Exchange (ETDEWEB)

    Groessle, Robin

    2015-11-27

    The scope of the thesis is the infrared absorption spectroscopy of liquid hydrogen isotopologues with the tritium absorption infrared spectroscopy (TApIR) experiment at the tritium laboratory Karlsruhe (TLK). The calibration process from the sample preparation to the reference measurements are described. A further issue is the classical evaluation of FTIR absorption spectra and the extension using the rolling circle filter (RCF) including the effects on statistical and systematical errors. The impact of thermal and nuclear spin temperature on the IR absorption spectra is discussed. An empirical based modeling for the IR absorption spectra of liquid hydrogen isotopologues is performed.

  6. Surgical strategies to improve fixation in the osteoporotic spine: the effects of tapping, cement augmentation, and screw trajectory.

    Science.gov (United States)

    Kuhns, Craig A; Reiter, Michael; Pfeiffer, Ferris; Choma, Theodore J

    2014-02-01

    Study Design Biomechanical study of pedicle screw fixation in osteoporotic bone. Objective To investigate whether it is better to tap or not tap osteoporotic bone prior to placing a cement-augmented pedicle screw. Methods Initially, we evaluated load to failure of screws placed in cancellous bone blocks with or without prior tapping as well as after varying the depths of tapping prior to screw insertion. Then we evaluated load to failure of screws placed in bone block models with a straight-ahead screw trajectory as well as with screws having a 23-degree cephalad trajectory (toward the end plate). These techniques were tested with nonaugmented (NA) screws as well as with bioactive cement (BioC) augmentation prior to screw insertion. Results In the NA group, pretapping decreased fixation strength in a dose-dependent fashion. In the BioC group, the tapped screws had significantly greater loads to failure (p tapping prior to cement augmentation will substantially improve fixation when compared with not tapping. Angulating screws more cephalad also seems to enhance aging spine fixation.

  7. Transversus abdominis plane (TAP) block in laparoscopic colorectal surgery improves postoperative pain management: a meta-analysis.

    Science.gov (United States)

    Hain, E; Maggiori, L; Prost À la Denise, J; Panis, Y

    2018-04-01

    Transversus abdominis plane (TAP) block is a locoregional anaesthesia technique of growing interest in abdominal surgery. However, its efficacy following laparoscopic colorectal surgery is still debated. This meta-analysis aimed to assess the efficacy of TAP block after laparoscopic colorectal surgery. All comparative studies focusing on TAP block after laparoscopic colorectal surgery have been systematically identified through the MEDLINE database, reviewed and included. Meta-analysis was performed according to the Mantel-Haenszel method for random effects. End-points included postoperative opioid consumption, morbidity, time to first bowel movement and length of hospital stay. A total of 13 studies, including 7 randomized controlled trials, were included, comprising a total of 600 patients who underwent laparoscopic colorectal surgery with TAP block, compared with 762 patients without TAP block. Meta-analysis of these studies showed that TAP block was associated with a significantly reduced postoperative opioid consumption on the first day after surgery [weighted mean difference (WMD) -14.54 (-25.14; -3.94); P = 0.007] and a significantly shorter time to first bowel movement [WMD -0.53 (-0.61; -0.44); P plane (TAP) block in laparoscopic colorectal surgery improves postoperative opioid consumption and recovery of postoperative digestive function without any significant drawback. Colorectal Disease © 2018 The Association of Coloproctology of Great Britain and Ireland.

  8. Combined visual illusion effects on the perceived index of difficulty and movement outcomes in discrete and continuous fitts' tapping.

    Science.gov (United States)

    Alphonsa, Sushma; Dai, Boyi; Benham-Deal, Tami; Zhu, Qin

    2016-01-01

    The speed-accuracy trade-off is a fundamental movement problem that has been extensively investigated. It has been established that the speed at which one can move to tap targets depends on how large the targets are and how far they are apart. These spatial properties of the targets can be quantified by the index of difficulty (ID). Two visual illusions are known to affect the perception of target size and movement amplitude: the Ebbinghaus illusion and Muller-Lyer illusion. We created visual images that combined these two visual illusions to manipulate the perceived ID, and then examined people's visual perception of the targets in illusory context as well as their performance in tapping those targets in both discrete and continuous manners. The findings revealed that the combined visual illusions affected the perceived ID similarly in both discrete and continuous judgment conditions. However, the movement outcomes were affected by the combined visual illusions according to the tapping mode. In discrete tapping, the combined visual illusions affected both movement accuracy and movement amplitude such that the effective ID resembled the perceived ID. In continuous tapping, none of the movement outcomes were affected by the combined visual illusions. Participants tapped the targets with higher speed and accuracy in all visual conditions. Based on these findings, we concluded that distinct visual-motor control mechanisms were responsible for execution of discrete and continuous Fitts' tapping. Although discrete tapping relies on allocentric information (object-centered) to plan for action, continuous tapping relies on egocentric information (self-centered) to control for action. The planning-control model for rapid aiming movements is supported.

  9. Ultrasound-guided transversus abdominis plane (TAP) block: a useful adjunct in the management of postoperative respiratory failure.

    Science.gov (United States)

    Singh, Mandeep; Chin, Ki Jinn; Chan, Vincent

    2011-06-01

    The ultrasound-guided transversus abdominis plane (TAP) block is a useful tool in controlling postoperative pain following abdominal surgery. The bilateral ultrasound-guided TAP blocks successfully managed the pain of a patient presenting with hypoxemia and respiratory failure in the Post-anesthesia Care Unit, following a laparotomy for small bowel obstruction during general anesthesia. The TAP block reduced systemic opioid requirements and opioid-induced sedation and respiratory depression, improved patient compliance with non-invasive positive pressure ventilation, and prevented the need for intubation and ventilation in the intensive care unit. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. Radiation induced change in the affinity of a plastic resin to chlorine contained in artificial tap water

    International Nuclear Information System (INIS)

    Fujiyoshi, Ryoko; Sawamura, Sadashi; Katayama, Meiseki

    1985-01-01

    γ-Radiation curing of a polyacetal resin was attempted in order to eliminate the unsuitable property for the joints of tap water pipes. In the case of non-irradiated resin, almost all available chlorine (AC) contained in usual tap water disappeared. γ-Irradiation of the resin showed an indirect effect on eliminating such a property; that is, a decrease in the amount of AC from artificial tap water (test solution) showed a decrease to JIS (Japan Industrial Standards) level of requirement at certain absorption doses. However, it was also found that the decrease in the amount of AC from the test solution increased with time after γ-irradiation. (author)

  11. Rhythmic synchronization tapping to an audio–visual metronome in budgerigars

    Science.gov (United States)

    Hasegawa, Ai; Okanoya, Kazuo; Hasegawa, Toshikazu; Seki, Yoshimasa

    2011-01-01

    In all ages and countries, music and dance have constituted a central part in human culture and communication. Recently, vocal-learning animals such as parrots and elephants have been found to share rhythmic ability with humans. Thus, we investigated the rhythmic synchronization of budgerigars, a vocal-mimicking parrot species, under controlled conditions and a systematically designed experimental paradigm as a first step in understanding the evolution of musical entrainment. We trained eight budgerigars to perform isochronous tapping tasks in which they pecked a key to the rhythm of audio–visual metronome-like stimuli. The budgerigars showed evidence of entrainment to external stimuli over a wide range of tempos. They seemed to be inherently inclined to tap at fast tempos, which have a similar time scale to the rhythm of budgerigars' natural vocalizations. We suggest that vocal learning might have contributed to their performance, which resembled that of humans. PMID:22355637

  12. Rhythmic synchronization tapping to an audio-visual metronome in budgerigars.

    Science.gov (United States)

    Hasegawa, Ai; Okanoya, Kazuo; Hasegawa, Toshikazu; Seki, Yoshimasa

    2011-01-01

    In all ages and countries, music and dance have constituted a central part in human culture and communication. Recently, vocal-learning animals such as parrots and elephants have been found to share rhythmic ability with humans. Thus, we investigated the rhythmic synchronization of budgerigars, a vocal-mimicking parrot species, under controlled conditions and a systematically designed experimental paradigm as a first step in understanding the evolution of musical entrainment. We trained eight budgerigars to perform isochronous tapping tasks in which they pecked a key to the rhythm of audio-visual metronome-like stimuli. The budgerigars showed evidence of entrainment to external stimuli over a wide range of tempos. They seemed to be inherently inclined to tap at fast tempos, which have a similar time scale to the rhythm of budgerigars' natural vocalizations. We suggest that vocal learning might have contributed to their performance, which resembled that of humans.

  13. Existence of Insecticides in Tap Drinking Surface and Ground Water in Dakahlyia Governorate, Egypt in 2011

    Directory of Open Access Journals (Sweden)

    RA Mandour

    2011-12-01

    Full Text Available Background: The environmental degradation products of pesticides may enter drinking water and result in serious health problems. Objective: To evaluate the occurrence of insecticides in drinking surface and ground water in Dakahlyia Governorate, northern Egypt in 2011. Methods: We studied blood samples collected from 36 consecutive patients diagnosed with pesticides poisoning and 36 tap drinking water (surface and ground. Blood and water samples were analyzed for pesticides using gas chromatography-electron captured detector (GC-ECD. In addition, blood samples were analyzed for plasma pseudo-cholinesterase level (PChE and red blood cells acetyl cholinesterase activity (AChE. Results: The results confirmed the presence of high concentrations of insecticides, including organonitrogenous and organochlorine in tap drinking surface and ground water. Conclusion: Drinking water contaminated with insecticides constitutes an important health concern in Dakahlyia governorate, Egypt.

  14. Calcium contained tap water phenomena: students misconception patterns of acids-bases concept

    Science.gov (United States)

    Liliasari, S.; Albaiti, A.; Wahyudi, A.

    2018-05-01

    Acids and bases concept is very important and fundamental concept in learning chemistry. It is one of the chemistry subjects considered as an abstract and difficult concept to understand. The aim of this research was to explore student’s misconception pattern about acids and bases phenomena in daily life, such as calcium contained tap water. This was a qualitative research with descriptive methods. Participants were 546 undergraduate students of chemistry education and chemistry program, and graduate students of chemistry education in West Java, Indonesia. The test to explore students’ misconception about this phenomena was essay test. The results showed that there were five patterns of students’ misconception in explaining the phenomena of calcium carbonate precipitation on heating tap water. Students used irrelevant concepts in explaining this phenomena, i.e. temporary hardness, coagulation, density, and phase concepts. No students had right answer in explaining this phenomena. This research contributes to design meaningful learning and to achieve better understanding.

  15. Tunable and reconfigurable multi-tap microwave photonic filter based on dynamic Brillouin gratings in fibers.

    Science.gov (United States)

    Sancho, J; Primerov, N; Chin, S; Antman, Y; Zadok, A; Sales, S; Thévenaz, L

    2012-03-12

    We propose and experimentally demonstrate new architectures to realize multi-tap microwave photonic filters, based on the generation of a single or multiple dynamic Brillouin gratings in polarization maintaining fibers. The spectral range and selectivity of the proposed periodic filters is extensively tunable, simply by reconfiguring the positions and the number of dynamic gratings along the fiber respectively. In this paper, we present a complete analysis of three different configurations comprising a microwave photonic filter implementation: a simple notch-type Mach-Zehnder approach with a single movable dynamic grating, a multi-tap performance based on multiple dynamic gratings and finally a stationary grating configuration based on the phase modulation of two counter-propagating optical waves by a common pseudo-random bit sequence (PRBS).

  16. Assessment of the radiological quality of tap waters 2008-2009

    International Nuclear Information System (INIS)

    Caamano, Delphine; Tracol, Raphael; Guillotin, Laetitia; Jedor, Beatrice; Davezac, Henri; Loyen, Jeanne

    2011-06-01

    After a recall of the context (radioactivity, origin of natural radioactivity in waters, exposure of population to natural radioactivity and health impact, indicators of water radiological quality, presence of uranium in water), this document reports a study which is based on the health control of water radiological quality by regional health agencies, on the analysis of natural and artificial radionuclides, on a survey on tap water radiological quality performed in 2009 by regional health agencies, and on an inventory of results related to the presence of radon in water performed by the IRSN and these agencies. The obtained results are presented and discussed in terms of factors impacting the result representativeness, of generalisation of the implementation of a health control, of tap water radiological quality. It is outlined that the uranium-related chemical risk is higher than the radiological risk

  17. Defensive spending on tap water substitutes: the value of reducing perceived health risks.

    Science.gov (United States)

    Dupont, Diane P; Jahan, Nowshin

    2012-03-01

    We examine factors that explain consumer spending on tap water substitutes using information from a national survey undertaken with a representative set of Canadian respondents. We develop a model to predict the percentage of households that undertake such spending for the purpose of reducing perceived health risks from tap water consumption. Using results from the model we estimate the magnitude of defensive expenditures to be over half a billion dollars (2010 US$) per year for Canada, as a whole. This is equivalent to approximately $48 per household per year or about $19 per person per year. Residents of Ontario, the province in which an Escherichia coli incident took place in 2000, have the highest willingness-to-pay of approximately $60 per household per year.

  18. Negative magnetoresistance without well-defined chirality in the Weyl semimetal TaP.

    Science.gov (United States)

    Arnold, Frank; Shekhar, Chandra; Wu, Shu-Chun; Sun, Yan; Dos Reis, Ricardo Donizeth; Kumar, Nitesh; Naumann, Marcel; Ajeesh, Mukkattu O; Schmidt, Marcus; Grushin, Adolfo G; Bardarson, Jens H; Baenitz, Michael; Sokolov, Dmitry; Borrmann, Horst; Nicklas, Michael; Felser, Claudia; Hassinger, Elena; Yan, Binghai

    2016-05-17

    Weyl semimetals (WSMs) are topological quantum states wherein the electronic bands disperse linearly around pairs of nodes with fixed chirality, the Weyl points. In WSMs, nonorthogonal electric and magnetic fields induce an exotic phenomenon known as the chiral anomaly, resulting in an unconventional negative longitudinal magnetoresistance, the chiral-magnetic effect. However, it remains an open question to which extent this effect survives when chirality is not well-defined. Here, we establish the detailed Fermi-surface topology of the recently identified WSM TaP via combined angle-resolved quantum-oscillation spectra and band-structure calculations. The Fermi surface forms banana-shaped electron and hole pockets surrounding pairs of Weyl points. Although this means that chirality is ill-defined in TaP, we observe a large negative longitudinal magnetoresistance. We show that the magnetoresistance can be affected by a magnetic field-induced inhomogeneous current distribution inside the sample.

  19. Differing Dynamics of Intrapersonal and Interpersonal Coordination: Two-finger and Four-Finger Tapping Experiments.

    Directory of Open Access Journals (Sweden)

    Kentaro Kodama

    Full Text Available Finger-tapping experiments were conducted to examine whether the dynamics of intrapersonal and interpersonal coordination systems can be described equally by the Haken-Kelso-Bunz model, which describes inter-limb coordination dynamics. This article reports the results of finger-tapping experiments conducted in both systems. Two within-subject factors were investigated: the phase mode and the number of fingers. In the intrapersonal experiment (Experiment 1, the participants were asked to tap, paced by a gradually hastening auditory metronome, looking at their fingers moving, using the index finger in the two finger condition, or the index and middle finger in the four-finger condition. In the interpersonal experiment (Experiment 2, pairs of participants performed the task while each participant used the outside hand, tapping with the index finger in the two finger condition, or the index and middle finger in the four-finger condition. Some results did not agree with the HKB model predictions. First, from Experiment 1, no significant difference was observed in the movement stability between the in-phase and anti-phase modes in the two finger condition. Second, from Experiment 2, no significant difference was found in the movement stability between the in-phase and anti-phase mode in the four-finger condition. From these findings, different coordination dynamics were inferred between intrapersonal and interpersonal coordination systems against prediction from the previous studies. Results were discussed according to differences between intrapersonal and interpersonal coordination systems in the availability of perceptual information and the complexity in the interaction between limbs derived from a nested structure.

  20. Emotional Freedom Technique (EFT) Tapping for Post Sectio Caesaria Patient: Decrease Anxiety and Increase Early Mobilization

    OpenAIRE

    Rusmini, Rusmini; Suparmi, Suparmi; Musdalifah, Ulfah

    2013-01-01

    The objective of the study is to evaluate the level of anxiety and early mobilization using the Emotional Freedom Technique (EFT): Tapping on patients post partum post secsio Caesaria before and after intervention period both control and experimental group. Design Quasi-experimental two group design was applied in the study. Forty two mothers with primipara post secsio Caesaria were recruited. Data analysis in the study included correlation, paird t-test, and independent t-test. The findings ...

  1. Assessment of drinking water quality at the tap using fluorescence spectroscopy

    OpenAIRE

    Heibati, Masoumeh; Stedmon, Colin A; Stenroth, Karolina; Rauch, Sebastien; Toljander, Jonas; Säve-Söderbergh, Melle; Murphy, Kathleen R.

    2017-01-01

    Treated drinking water may become contaminated while travelling in the distribution system on the way to consumers. Elevated dissolved organic matter (DOM) at the tap relative to the water leaving the treatment plant is a potential indicator of contamination, and can be measured sensitively, inexpensively and potentially on-line via fluorescence and absorbance spectroscopy. Detecting elevated DOM requires potential contamination events to be distinguished from natural fluctuations in the syst...

  2. Tip Effect of the Tapping Mode of Atomic Force Microscope in Viscous Fluid Environments.

    Science.gov (United States)

    Shih, Hua-Ju; Shih, Po-Jen

    2015-07-28

    Atomic force microscope with applicable types of operation in a liquid environment is widely used to scan the contours of biological specimens. The contact mode of operation allows a tip to touch a specimen directly but sometimes it damages the specimen; thus, a tapping mode of operation may replace the contact mode. The tapping mode triggers the cantilever of the microscope approximately at resonance frequencies, and so the tip periodically knocks the specimen. It is well known that the cantilever induces extra liquid pressure that leads to drift in the resonance frequency. Studies have noted that the heights of protein surfaces measured via the tapping mode of an atomic force microscope are ~25% smaller than those measured by other methods. This discrepancy may be attributable to the induced superficial hydrodynamic pressure, which is worth investigating. In this paper, we introduce a semi-analytical method to analyze the pressure distribution of various tip geometries. According to our analysis, the maximum hydrodynamic pressure on the specimen caused by a cone-shaped tip is ~0.5 Pa, which can, for example, pre-deform a cell by several nanometers in compression before the tip taps it. Moreover, the pressure calculated on the surface of the specimen is 20 times larger than the pressure without considering the tip effect; these results have not been motioned in other papers. Dominating factors, such as surface heights of protein surface, mechanical stiffness of protein increasing with loading velocity, and radius of tip affecting the local pressure of specimen, are also addressed in this study.

  3. Occurrence and sources of bromate in chlorinated tap drinking water in Metropolitan Manila, Philippines.

    Science.gov (United States)

    Genuino, Homer C; Espino, Maria Pythias B

    2012-04-01

    Significant levels of potentially carcinogenic bromate were measured in chlorinated tap drinking water in Metropolitan Manila, Philippines, using an optimized ion-chromatographic method. This method can quantify bromate in water down to 4.5 μg l⁻¹ by employing a postcolumn reaction with acidic fuchsin and subsequent spectrophotometric detection. The concentration of bromate in tap drinking water samples collected from 21 locations in cities and municipalities within the 9-month study period ranged from 7 to 138 μg l⁻¹. The average bromate concentration of all tap drinking water samples was 66 μg l⁻¹ (n = 567), almost seven times greater than the current regulatory limit in the country. The levels of bromate in other water types were also determined to identify the sources of bromate found in the distribution lines and to further uncover contaminated sites. The concentration of bromate in water sourced from two rivers and two water treatment plants ranged from 15 to 80 and 12 to 101 μg l⁻¹, respectively. Rainwater did not contribute bromate in rivers but decreased bromate level by dilution. Groundwater and wastewater samples showed bromate concentrations as high as 246 and 342 μg l⁻¹, respectively. Bromate presence in tap drinking water can be linked to pollution in natural water bodies and the practice of using hypochlorite chemicals in addition to gaseous chlorine for water disinfection. This study established the levels, occurrence, and possible sources of bromate in local drinking water supplies.

  4. Technologies for decreasing the tap temperature to save energy in steel foundries

    Science.gov (United States)

    Biswas, Siddhartha

    Steel foundries are one of the most energy intensive industries. The increasing concerns over volatile energy cost and carbon dioxide emission have pushed foundries to improve efficiency and hence decrease electrical energy consumption. Statistical analysis of industrial survey data was combined with computational fluid dynamics (CFD) modeling to investigate the best industrial practices and opportunities to improve energy efficiency. Reducing tap temperature was identified as one of the important ways of reducing energy consumption. Steel foundries typically tap at 1650-1800°C (3000-3300°F) which is 100-250°C (150-450°F) higher than the pouring temperature. The steel temperature is elevated to compensate for the temperature loss associated with tapping, holding and transporting the liquid steel from the furnace to the pouring floor. Based on experimental investigations and CFD modeling of heat losses during holding in the ladle for different foundry practices, a spreadsheet calculator has been developed to calculate the optimum tap temperature for the specific foundry practices which will eliminate unnecessary superheating. The calculated results were compared and validated with industrial measurements. Improving the lining refractory is one significant way of reducing heat losses during holding of the steel in ladle. Silica sand linings are being used in steel foundries as an inexpensive and convenient material for short holding times and small volumes. The possibilities of improvements of silica sand linings by the addition of lower density cenospheres (hollow spheres), a byproduct of coal fired power plants, was studied through property measurements and laboratory trials.

  5. Operational Challenges in Gas-To-Liquid (GTL) Transportation Through Trans Alaska Pipeline System (TAPS)

    Energy Technology Data Exchange (ETDEWEB)

    Godwin A. Chukwu; Santanu Khataniar; Shirish Patil; Abhijit Dandekar

    2006-06-30

    Oil production from Alaskan North Slope oil fields has steadily declined. In the near future, ANS crude oil production will decline to such a level (200,000 to 400,000 bbl/day) that maintaining economic operation of the Trans-Alaska Pipeline System (TAPS) will require pumping alternative products through the system. Heavy oil deposits in the West Sak and Ugnu formations are a potential resource, although transporting these products involves addressing important sedimentation issues. One possibility is the use of Gas-to-Liquid (GTL) technology. Estimated recoverable gas reserves of 38 trillion cubic feet (TCF) on the North Slope of Alaska can be converted to liquid with GTL technology and combined with the heavy oils for a product suitable for pipeline transport. Issues that could affect transport of this such products through TAPS include pumpability of GTL and crude oil blends, cold restart of the pipeline following a prolonged winter shutdown, and solids deposition inside the pipeline. This study examined several key fluid properties of GTL, crude oil and four selected blends under TAPS operating conditions. Key measurements included Reid Vapor Pressure, density and viscosity, PVT properties, and solids deposition. Results showed that gel strength is not a significant factor for the ratios of GTL-crude oil blend mixtures (1:1; 1:2; 1:3; 1:4) tested under TAPS cold re-start conditions at temperatures above - 20 F, although Bingham fluid flow characteristics exhibited by the blends at low temperatures indicate high pumping power requirements following prolonged shutdown. Solids deposition is a major concern for all studied blends. For the commingled flow profile studied, decreased throughput can result in increased and more rapid solid deposition along the pipe wall, resulting in more frequent pigging of the pipeline or, if left unchecked, pipeline corrosion.

  6. Tapping Into Rate Flexibility: Musical Training Facilitates Synchronization Around Spontaneous Production Rates

    Directory of Open Access Journals (Sweden)

    Rebecca Scheurich

    2018-04-01

    Full Text Available The ability to flexibly adapt one’s behavior is critical for social tasks such as speech and music performance, in which individuals must coordinate the timing of their actions with others. Natural movement frequencies, also called spontaneous rates, constrain synchronization accuracy between partners during duet music performance, whereas musical training enhances synchronization accuracy. We investigated the combined influences of these factors on the flexibility with which individuals can synchronize their actions with sequences at different rates. First, we developed a novel musical task capable of measuring spontaneous rates in both musicians and non-musicians in which participants tapped the rhythm of a familiar melody while hearing the corresponding melody tones. The novel task was validated by similar measures of spontaneous rates generated by piano performance and by the tapping task from the same pianists. We then implemented the novel task with musicians and non-musicians as they synchronized tapping of a familiar melody with a metronome at their spontaneous rates, and at rates proportionally slower and faster than their spontaneous rates. Musicians synchronized more flexibly across rates than non-musicians, indicated by greater synchronization accuracy. Additionally, musicians showed greater engagement of error correction mechanisms than non-musicians. Finally, differences in flexibility were characterized by more recurrent (repetitive and patterned synchronization in non-musicians, indicative of greater temporal rigidity.

  7. Resistivity of Weyl semimetals NbP and TaP under pressure

    International Nuclear Information System (INIS)

    Einaga, M.; Shimizu, K.; Hu, J.; Mao, Z.Q.; Politano, A.

    2017-01-01

    The resistivity of Weyl semimetals NbP and TaP has been investigated as a function of pressure and temperature. The behaviour of the resistivity as a function of pressure and temperature is closely correlated to the location of the Weyl points compared to the Fermi energy. The rapid increase of the resistivity in TaP and NbP under the application of 4.5 and 8.0 GPa is related with the shift of Weyl points, which affords a finite density of states near the Fermi energy. Specifically, we find that under pressure the Weyl points are situated above the Fermi energy. As regards the temperature behaviour, we detect a nonmonotonous behaviour of resistivity in TaP at 8.7 and 9.8 GPa as a function of temperature, whereas in the case of NbP the behaviour is more complicate. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. Force-chain evolution in a two-dimensional granular packing compacted by vertical tappings

    Science.gov (United States)

    Iikawa, Naoki; Bandi, M. M.; Katsuragi, Hiroaki

    2018-03-01

    We experimentally study the statistics of force-chain evolution in a vertically-tapped two-dimensional granular packing by using photoelastic disks. In this experiment, the tapped granular packing is gradually compacted. During the compaction, the isotropy of grain configurations is quantified by measuring the deviator anisotropy derived from fabric tensor, and then the evolution of force-chain structure is quantified by measuring the interparticle forces and force-chain orientational order parameter. As packing fraction increases, the interparticle force increases and finally saturates to an asymptotic value. Moreover, the grain configurations and force-chain structures become isotropically random as the tapping-induced compaction proceeds. In contrast, the total length of force chains remains unchanged. From the correlations of those parameters, we find two relations: (i) a positive correlation between the isotropy of grain configurations and the disordering of force-chain orientations, and (ii) a negative correlation between the increasing of interparticle forces and the disordering of force-chain orientations. These relations are universally held regardless of the mode of particle motions with or without convection.

  9. Establishment of an easy Ic measurement method of HTS superconducting tapes using clipped voltage taps

    International Nuclear Information System (INIS)

    Shin, Hyung Seop; Nisay, Arman; Dedicatoria, Marlon; Sim, Ki Deok

    2014-01-01

    The critical current, I c of HTS superconducting tapes can be measured by transport or contactless method. Practically, the transport method using the four-probe method is the most common. In this study, a simple test procedure by clipping the voltage lead taps have been introduced instead of soldering which reduces time and effort and thereby achieving a much faster measurement of I c . When using a pair of iron clips, I c value decreased as compared with the measured one by standard method using soldered voltage taps and varies with the width of the clipped specimen part. However, when using a pure Cu clip, both by clipping and by soldering voltage taps give a comparable result and I c measured are equal and close to the samples specification. As a result, material to be used as voltage clip should be considered and should not influence the potential voltage between the leads during I c measurement. Furthermore, the simulation result of magnetic flux during I c measurement test showed that the decrease of I c observed in the experiment is due to the magnetic flux density, By produced at the clipped part of the sample by the operating current with iron clips attached to the sample.

  10. Freezing during tapping tasks in patients with advanced Parkinson's disease and freezing of gait.

    Science.gov (United States)

    Delval, Arnaud; Defebvre, Luc; Tard, Céline

    2017-01-01

    Parkinson's disease patients with freezing of gait also experience sudden motor blocks (freezing) during other repetitive motor tasks. We assessed the proportion of patients with advanced PD and freezing of gait who also displayed segmental "freezing" in tapping tasks. Fifteen Parkinson's disease patients with freezing of gait were assessed. Freezing of gait was evaluated using a standardized gait trajectory with the usual triggers. Patients performed repetitive tapping movements (as described in the MDS-UPDRS task) with the hands or the feet in the presence or absence of a metronome set to 4 Hz. Movements were recorded with a video motion system. The primary endpoint was the occurrence of segmental freezing in these tapping tasks. The secondary endpoints were (i) the relationship between segmental episodic phenomena and FoG severity, and (ii) the reliability of the measurements. For the upper limbs, freezing was observed more frequently with a metronome (21% of trials) than without a metronome (5%). For the lower limbs, the incidence of freezing was higher than for the upper limbs, and was again observed more frequently in the presence of an auditory cue (47%) than in its absence (14%). Although freezing of the lower limbs was easily assessed during an MDS-UPDRS task with a metronome, it was not correlated with the severity of freezing of gait (as evaluated during a standardized gait trajectory). Only this latter was a reliable measurement in patients with advanced Parkinson's disease.

  11. True Tapping Mode Scanning Near-Field Optical Microscopy with Bent Glass Fiber Probes.

    Science.gov (United States)

    Smirnov, A; Yasinskii, V M; Filimonenko, D S; Rostova, E; Dietler, G; Sekatskii, S K

    2018-01-01

    In scanning near-field optical microscopy, the most popular probes are made of sharpened glass fiber attached to a quartz tuning fork (TF) and exploiting the shear force-based feedback. The use of tapping mode feedback could be preferable. Such an approach can be realized, for example, using bent fiber probes. Detailed analysis of fiber vibration modes shows that realization of truly tapping mode of the probe dithering requires an extreme caution. In case of using the second resonance mode, probes vibrate mostly in shear force mode unless the bending radius is rather small (ca. 0.3 mm) and the probe's tip is short. Otherwise, the shear force character of the dithering persists. Probes having these characteristics were prepared by irradiation of a tapered etched glass fiber with a CW CO 2 laser. These probes were attached to the TF in double resonance conditions which enables achieving significant quality factor (4000-6000) of the TF + probe system (Cherkun et al., 2006). We also show that, to achieve a truly tapping character, dithering, short, and not exceeding 3 mm lengths of a freestanding part of bent fiber probe beam should also be used in the case of nonresonant excitation.

  12. Tapping Into Rate Flexibility: Musical Training Facilitates Synchronization Around Spontaneous Production Rates

    Science.gov (United States)

    Scheurich, Rebecca; Zamm, Anna; Palmer, Caroline

    2018-01-01

    The ability to flexibly adapt one’s behavior is critical for social tasks such as speech and music performance, in which individuals must coordinate the timing of their actions with others. Natural movement frequencies, also called spontaneous rates, constrain synchronization accuracy between partners during duet music performance, whereas musical training enhances synchronization accuracy. We investigated the combined influences of these factors on the flexibility with which individuals can synchronize their actions with sequences at different rates. First, we developed a novel musical task capable of measuring spontaneous rates in both musicians and non-musicians in which participants tapped the rhythm of a familiar melody while hearing the corresponding melody tones. The novel task was validated by similar measures of spontaneous rates generated by piano performance and by the tapping task from the same pianists. We then implemented the novel task with musicians and non-musicians as they synchronized tapping of a familiar melody with a metronome at their spontaneous rates, and at rates proportionally slower and faster than their spontaneous rates. Musicians synchronized more flexibly across rates than non-musicians, indicated by greater synchronization accuracy. Additionally, musicians showed greater engagement of error correction mechanisms than non-musicians. Finally, differences in flexibility were characterized by more recurrent (repetitive) and patterned synchronization in non-musicians, indicative of greater temporal rigidity. PMID:29681872

  13. Aplication Of PGR IAA And Kinetin On Rubber Clones To Accelarate Mature Tapping

    Directory of Open Access Journals (Sweden)

    Try Koryati

    2017-09-01

    Full Text Available This study aims to determine the most appropriate concentration of IAA hormones Kinetin on rubber clones to accelerate the mature tapping. Experiments have been carried out in Karang Inong Plantation PTP N I Langsa East Aceh. This study is arranged in two factors of Nested Design. Clones factor is consisted of 5 level and IAA hormon Kinetin factor has 7 levels. The results showed that the concentration of IAA hormones Kinetin is different to each clone to accelerate mature tapping. Application of IAA hormone Kinetin significantly affect the parameters of girth bark thickness number of latex vessels latex vessel diameter leaf area and the amount of chlorophyll. Application of IAA 600ppm Kinetin 60 ppm H6 show the largest increase on the girth. Clone treatment is also has significant effect on all parameters but the largest girth found in clones PB 330 and IRR 5. Combination of Clones with IAA hormone Kinetin significantly affects the bark thickness the number of latex vessels and latex vessel diameter. Application of IAA 400 ppm Kinetin 60 ppm has no significant effect on girth but able to accelerate the mature tapping particularly for clones PB 330 and IRR5 K2H4 and K5H4 as indicated by girth size namely 48.15 cm and 48.20 cm respectively at planting age 46 months.

  14. Linearity of amplitude and phase in tapping-mode atomic force microscopy

    International Nuclear Information System (INIS)

    Salapaka, M.V.; Chen, D.J.; Cleveland, J.P.

    2000-01-01

    In this article tapping-mode atomic force microscope dynamics is studied. The existence of a periodic orbit at the forcing frequency is shown under unrestrictive conditions. The dynamics is further analyzed using the impact model for the tip-sample interaction and a spring-mass-damper model of the cantilever. Stability of the periodic orbit is established. Closed-form expressions for various variables important in tapping-mode imaging are obtained. The linear relationship of the amplitude and the sine of the phase of the first harmonic of the periodic orbit with respect to cantilever-sample offset is shown. The study reinforces gentleness of the tapping-mode on the sample. Experimental results are in excellent qualitative agreement with the theoretical predictions. The linear relationship of the sine of the phase and the amplitude can be used to infer sample properties. The comparison between the theory and the experiments indicates essential features that are needed in a more refined model

  15. Head position affects the direction of occlusal force during tapping movement.

    Science.gov (United States)

    Nakamura, K; Minami, I; Wada, J; Ikawa, Y; Wakabayashi, N

    2018-05-01

    Despite numerous reports describing the relationship between head position and mandibular movement in human subjects, the direction and magnitude of force at the occlusal contacts have not been investigated in relation to head position. The objective was to investigate the effect of head position on the direction of occlusal force while subjects performed a tapping movement. Twenty-three healthy adult subjects were asked to sit on a chair with their back upright and to perform 15 tapping movements in five different head positions: natural head position (control); forward; backward; and right and left rolled. The direction and magnitude of force were measured using a small triaxial force sensor. The Wilcoxon signed-rank test and Bonferroni test were used to compare head positions in each angle of the anteroposterior axis direction and the lateral axis direction with respect to the superior axis. The force element in the anteroposterior axis shifted to the forward direction in the head position pitched backward, compared with control, pitched forward and rolled left positions (P = .02, tapping movement can be performed in a relaxed position without anteroposterior and lateral loading. © 2018 John Wiley & Sons Ltd.

  16. Investigation of formaldehyde pollution of tap water and rain water using a novel visual colorimetry.

    Science.gov (United States)

    Murai, K; Okano, M; Kuramitz, H; Hata, N; Kawakami, T; Taguchi, S

    2008-01-01

    The pollution of tap water and rain water with formaldehyde in Toyama Pref., Japan was investigated by means of a simple, rapid and cost-effective visual colorimetry developed by us. The levels of formaldehyde in three tap waters from different sources of dams on mountainside and a well-water pumped in urban area in Toyama Pref. were lower than 0.01 mg L(-1) that was the detection limit of the colorimetry. On the other hand, rain waters were seriously polluted with formaldehyde. Rain waters were sampled from three different sites (urban area, top of hill and industrial area) in Toyama Pref. from autumn to winter in 2006. The levels of formaldehyde in the rain waters ranged from 0.07 to 0.30 mg L(-1). The analytical results by the visual colorimetry were in good agreement with those obtained by GC-MS method. It was confirmed that the colorimetry is excellent for practical use for the determination of formaldehyde. It must be concerned about the pollution of rainwater with formaldehyde, when rain water is applied for tap water and miscellaneous purpose. Copyright IWA Publishing 2008.

  17. Tumor-activated prodrug (TAP)-conjugated nanoparticles with cleavable domains for safe doxorubicin delivery.

    Science.gov (United States)

    Guarnieri, Daniela; Biondi, Marco; Yu, Hui; Belli, Valentina; Falanga, Andrea P; Cantisani, Marco; Galdiero, Stefania; Netti, Paolo A

    2015-03-01

    A major issue in chemotherapy is the lack of specificity of many antitumor drugs, which cause severe side effects and an impaired therapeutic response. Here we report on the design and characterization of model tumor activated prodrug-conjugated polystyrene (PS) nanoparticles (TAP-NPs) for the release of doxorubicin (Dox) triggered by matrix metalloprotease-2 (MMP2) enzyme, which is overexpressed in the extracellular matrix of tumors. In particular, TAP-NPs were produced by attaching Dox to poly(ethylene glycol) (PEG) through two MMP2-cleavable enzymes. The resulting adduct was then tethered to PS NPs. Results showed that Dox release was actually triggered by MMP2 cleavage and was dependent on enzyme concentration, with a plateau around 20 nM. Furthermore, significant cell cytotoxicity was observed towards three cell lines only in the presence of MMP2, but not in cells without enzyme pre-treatment, even after NP internalization by cells. These findings indicate the potential of TAP-NPs as suitable nanocarriers for an on demand, tumor--specific delivery of antitumor drugs after the response to an endogenous stimulus. Further advancements will focus on the translation of this production technology to biodegradable systems for the safe transport of cytotoxic drug to tumor tissues. © 2014 Wiley Periodicals, Inc.

  18. Fluoride Intake through Consumption of Tap Water and Bottled Water in Belgium

    Directory of Open Access Journals (Sweden)

    Herman van Oyen

    2009-05-01

    Full Text Available There is a tendency to align higher levels of fluoride in natural mineral water with the existing higher levels in tap water. Treatment of natural mineral waters could harm the preservation of their natural character. In this study fluoride intake through bottled and tap water consumption in the Belgian adult population was assessed, taking into account regional differences. A deterministic approach was used whereby consumption quantities of tap water and different brands of bottled water were linked with their respective fluoride concentrations. Data from the national food consumption survey (2004 were used and the Nusser methodology was applied to obtain usual intake estimates. Mean intake of fluoride through total water consumption in Flanders was 1.4±0.7 mg/day (97.5th percentile: 3.1 mg/day, while in the Walloon region it was on average 0.9±0.6 mg/day (97.5th percentile: 2.4 mg/day. The probability of exceeding the UL of 7 mg per day via a normal diet was estimated to be low. Consequently, there is no need to revise the existing norms, but higher fluoride concentrations should be more clearly indicated on the labels. Reliable data about total dietary fluoride intake in children, including intake of fluoride via tooth paste and food supplements, are needed.

  19. Pharmaceuticals in tap water: human health risk assessment and proposed monitoring framework in China.

    Science.gov (United States)

    Leung, Ho Wing; Jin, Ling; Wei, Si; Tsui, Mirabelle Mei Po; Zhou, Bingsheng; Jiao, Liping; Cheung, Pak Chuen; Chun, Yiu Kan; Murphy, Margaret Burkhardt; Lam, Paul Kwan Sing

    2013-07-01

    Pharmaceuticals are known to contaminate tap water worldwide, but the relevant human health risks have not been assessed in China. We monitored 32 pharmaceuticals in Chinese tap water and evaluated the life-long human health risks of exposure in order to provide information for future prioritization and risk management. We analyzed samples (n = 113) from 13 cities and compared detected concentrations with existing or newly-derived safety levels for assessing risk quotients (RQs) at different life stages, excluding the prenatal stage. We detected 17 pharmaceuticals in 89% of samples, with most detectable concentrations (92%) at risk levels, but 4 (i.e., dimetridazole, thiamphenicol, sulfamethazine, and clarithromycin) were found to have at least one life-stage RQ ≥ 0.01, especially for the infant and child life stages, and should be considered of high priority for management. We propose an indicator-based monitoring framework for providing information for source identification, water treatment effectiveness, and water safety management in China. Chinese tap water is an additional route of human exposure to pharmaceuticals, particularly for dimetridazole, although the risk to human health is low based on current toxicity data. Pharmaceutical detection and application of the proposed monitoring framework can be used for water source protection and risk management in China and elsewhere.

  20. Adding Sufentanil to TAP Block Hyperbaric Bupivacaine Decreases Post-Cesarean Delivery Morphine Consumption

    Directory of Open Access Journals (Sweden)

    Laleh Eslamian

    2016-04-01

    Full Text Available Pain management is crucially important in the postoperative period as it increases patient comfort and satisfaction. The primary outcome of present study was to evaluate the effect of sufentanil added to hyperbaric bupivacaine solution 0.25% in transversus abdominis plane (TAP block, on postoperative analgesic consumption. Fifty ASA physical status I–II term primiparous single-tone pregnant women aged 20–40 years scheduled for elective cesarean delivery with Pfannenstiel incision under general anaesthesia were enrolled in this randomized, double-blind, placebo-controlled trial. Ultrasound guided TAP block was performed at the end of surgery. Patients were randomly enrolled into two groups. Patients in the study group received 20 ml of hyperbaric bupivacaine 0.25% plus 1mL of sufentanil on either side while patients in the placebo group were administered 20 ml of hyperbaric bupivacaine 0.25% along with 1mL of placebo. Post-cesarean delivery visual analogue scale (VAS for pain and morphine usage were measured and recorded. The morphine consumption was significantly less in the study group (37.2 ± 16.1 mg than the control group (52.8 ± 16.7 mg, P =0.002.The VAS for pain both in rest and coughing were same in groups. Sufentanil added to 0.25% hyperbaric bupivacaine in TAP block decreases post cesarean delivery morphine consumption.

  1. Measurement and Evaluation of Finger Tapping Movements Using Log-linearized Gaussian Mixture Networks

    Directory of Open Access Journals (Sweden)

    Masaru Yokoe

    2009-03-01

    Full Text Available This paper proposes a method to quantitatively measure and evaluate finger tapping movements for the assessment of motor function using log-linearized Gaussian mixture networks (LLGMNs. First, finger tapping movements are measured using magnetic sensors, and eleven indices are computed for evaluation. After standardizing these indices based on those of normal subjects, they are input to LLGMNs to assess motor function. Then, motor ability is probabilistically discriminated to determine whether it is normal or not using a classifier combined with the output of multiple LLGMNs based on bagging and entropy. This paper reports on evaluation and discrimination experiments performed on finger tapping movements in 33 Parkinson’s disease (PD patients and 32 normal elderly subjects. The results showed that the patients could be classified correctly in terms of their impairment status with a high degree of accuracy (average rate: 93:1 § 3:69% using 12 LLGMNs, which was about 5% higher than the results obtained using a single LLGMN.

  2. Residential tap water contamination following the Freedom Industries chemical spill: perceptions, water quality, and health impacts.

    Science.gov (United States)

    Whelton, Andrew J; McMillan, LaKia; Connell, Matt; Kelley, Keven M; Gill, Jeff P; White, Kevin D; Gupta, Rahul; Dey, Rajarshi; Novy, Caroline

    2015-01-20

    During January 2014, an industrial solvent contaminated West Virginia’s Elk River and 15% of the state population’s tap water. A rapid in-home survey and water testing was conducted 2 weeks following the spill to understand resident perceptions, tap water chemical levels, and premise plumbing flushing effectiveness. Water odors were detected in all 10 homes sampled before and after premise plumbing flushing. Survey and medical data indicated flushing caused adverse health impacts. Bench-scale experiments and physiochemical property predictions showed flushing promoted chemical volatilization, and contaminants did not appreciably sorb into cross-linked polyethylene (PEX) pipe. Flushing reduced tap water 4-methylcyclohexanemethanol (4-MCHM) concentrations within some but not all homes. 4-MCHM was detected at unflushed (waters contained less 4-MCHM than the 1000 μg/L Centers for Disease Control drinking water limit, but one home exceeded the 120 μg/L drinking water limit established by independent toxicologists. Nearly all households refused to resume water use activities after flushing because of water safety concerns. Science based flushing protocols should be developed to expedite recovery, minimize health impacts, and reduce concentrations in homes when future events occur.

  3. Resistivity of Weyl semimetals NbP and TaP under pressure

    Energy Technology Data Exchange (ETDEWEB)

    Einaga, M.; Shimizu, K. [KYOKUGEN, Graduate School of Engineering Science, Osaka University, Toyonaka (Japan); Hu, J.; Mao, Z.Q. [Department of Physics and Engineering Physics, Tulane University, New Orleans, LA (United States); Politano, A. [Fondazione Istituto Italiano di Tecnologia, Graphene Labs, Genova (Italy)

    2017-08-15

    The resistivity of Weyl semimetals NbP and TaP has been investigated as a function of pressure and temperature. The behaviour of the resistivity as a function of pressure and temperature is closely correlated to the location of the Weyl points compared to the Fermi energy. The rapid increase of the resistivity in TaP and NbP under the application of 4.5 and 8.0 GPa is related with the shift of Weyl points, which affords a finite density of states near the Fermi energy. Specifically, we find that under pressure the Weyl points are situated above the Fermi energy. As regards the temperature behaviour, we detect a nonmonotonous behaviour of resistivity in TaP at 8.7 and 9.8 GPa as a function of temperature, whereas in the case of NbP the behaviour is more complicate. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  4. High Tap Density Li4Ti5O12 Microspheres: Synthetic Conditions and Advanced Electrochemical Performance

    KAUST Repository

    Ming, Jun; Zheng, Junwei; Zhou, Qun; Ren, Jianxin; Ming, Hai; Jia, Zhenyong; Zhang, Yanqing

    2017-01-01

    Preparation of uniform spherical Li4Ti5O12 with high tap density is significant to achieve a high volumetric energy density in lithium-ion batteries. Herein, Li4Ti5O12 micro-spheres with variable tap-density and tunable size distribution were synthesized by a newly designed industrial spray drying approach. The slurry concentration, sintering time and sintering conditions after spray, the effect of Li/Ti molar ratio on the lithium ion (Li+) storage capability were investigated. A narrow particle size distribution around 10 μm and high tap-density close to 1.4 g cm-3 of the Li4Ti5O12 spheres can be obtained under the optimized conditions. The Li4Ti5O12 spheres can deliver much higher capacity of 168 mAh g-1 at 1 C-rate and show high capacity retention of 97.7% over 400 cycles. The synthetic conditions are confirmed to be critical for improving the electron conductivity and Li+ diffusivity by adjusting the crystal and spatial structures. As-prepared high performance Li4Ti5O12 is an ideal electrode for Li-ion batteries or capacitors; meanwhile the presented approach is also applicable for preparing other kind of spherical materials.

  5. High Tap Density Li4Ti5O12 Microspheres: Synthetic Conditions and Advanced Electrochemical Performance

    KAUST Repository

    Ming, Jun

    2017-03-17

    Preparation of uniform spherical Li4Ti5O12 with high tap density is significant to achieve a high volumetric energy density in lithium-ion batteries. Herein, Li4Ti5O12 micro-spheres with variable tap-density and tunable size distribution were synthesized by a newly designed industrial spray drying approach. The slurry concentration, sintering time and sintering conditions after spray, the effect of Li/Ti molar ratio on the lithium ion (Li+) storage capability were investigated. A narrow particle size distribution around 10 μm and high tap-density close to 1.4 g cm-3 of the Li4Ti5O12 spheres can be obtained under the optimized conditions. The Li4Ti5O12 spheres can deliver much higher capacity of 168 mAh g-1 at 1 C-rate and show high capacity retention of 97.7% over 400 cycles. The synthetic conditions are confirmed to be critical for improving the electron conductivity and Li+ diffusivity by adjusting the crystal and spatial structures. As-prepared high performance Li4Ti5O12 is an ideal electrode for Li-ion batteries or capacitors; meanwhile the presented approach is also applicable for preparing other kind of spherical materials.

  6. True Tapping Mode Scanning Near-Field Optical Microscopy with Bent Glass Fiber Probes

    Directory of Open Access Journals (Sweden)

    A. Smirnov

    2018-01-01

    Full Text Available In scanning near-field optical microscopy, the most popular probes are made of sharpened glass fiber attached to a quartz tuning fork (TF and exploiting the shear force-based feedback. The use of tapping mode feedback could be preferable. Such an approach can be realized, for example, using bent fiber probes. Detailed analysis of fiber vibration modes shows that realization of truly tapping mode of the probe dithering requires an extreme caution. In case of using the second resonance mode, probes vibrate mostly in shear force mode unless the bending radius is rather small (ca. 0.3 mm and the probe’s tip is short. Otherwise, the shear force character of the dithering persists. Probes having these characteristics were prepared by irradiation of a tapered etched glass fiber with a CW CO2 laser. These probes were attached to the TF in double resonance conditions which enables achieving significant quality factor (4000–6000 of the TF + probe system (Cherkun et al., 2006. We also show that, to achieve a truly tapping character, dithering, short, and not exceeding 3 mm lengths of a freestanding part of bent fiber probe beam should also be used in the case of nonresonant excitation.

  7. Tap versus bottled water consumption: The influence of social norms, affect and image on consumer choice.

    Science.gov (United States)

    Etale, Anita; Jobin, Marilou; Siegrist, Michael

    2018-02-01

    What drives consumers to choose bottled water instead of tap water where the latter is safe, accessible, costs far less, and in spite of its environmental impacts? This research investigates the influence of hitherto unexplored psychological drivers in an attempt to generate a more holistic understanding of the phenomenon, and strategies for designing more effective consumption reduction campaigns. Using data from an internet survey of Swiss and German respondents (N = 849) we investigated the role of, social norms, affect and image on water consumption. Results suggest that these psychological factors play a role in water consumption choice. Convenience was the only contextual predictor - the inconvenience of transporting bottled water has a negative effect on its consumption, and a positive effect on tap water consumption. Although concern about the effect of bottled water on the environment was not a significant predictor of tap water consumption, we found that for some people, a link exists between environmental concern and consumption choice. Ways through which consumers may be more effectively influenced towards environmentally-friendly consumption are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Influence of storage conditions on aluminum concentrations in serum, dialysis fluid, urine, and tap water.

    Science.gov (United States)

    Wilhelm, M; Ohnesorge, F K

    1990-01-01

    The influence of storage temperature, vessel type, and treatment on alterations of aluminum (Al) concentrations in serum, urine, and dialysis fluid samples was studied at three different concentrations for each sample over an 18-month period. Furthermore, the influence of acidification on Al levels in tap water, urine, and dialysis fluid samples was studied over a four-month period. Al was measured by atomic absorption spectrometry. Sample storage in glass vessels was unsuitable, whereas only minor alterations of Al levels were observed with storage in polypropylene tubes, polystyrene tubes, and Monovettes. By using appropriate plastic containers, acid washing of the vessels showed no improvement. Frozen storage was superior compared with 4 degrees C, whereas storage at -80 degrees C offered no advantage compared with storage at -20 degrees C. Acidification of tap water samples was necessary to stabilize Al levels during storage. No striking effect of acidification on Al levels in urine and dialysis fluid samples was found. It is concluded that longterm storage of serum, urine, tap water, and dialysis fluid samples is possible if appropriate conditions are used.

  9. External radiation monitoring in TAPS and RAPS environs (1980-81) using TLD

    International Nuclear Information System (INIS)

    Basu, A.S.; Nambi, K.S.V.; Sunta, C.M.

    1983-01-01

    Results of environmental external radiation monitoring using quarterly integrated TLD measurements are presented for environments of the Tarapur Atomic Power Station (TAPS) and the Rajasthan Atomic Power Station (RAPS) for the two year monitoring period (1980-81). The data fit into the unimodal log-normal distribution except for locations where gaseous radioactivity escaping from the plant makes a significant contribution. The average natural radiation background in TAPS and RAPS environment is estimated to be 59.6 +- 4.7 mR yr -1 and 65.1 +- 9.8 mR yr -1 respectively. Contribution from the plant superimposed over the natural level leads frequently to bi-normal distribution. The effect of stack-released gaseous radioactivity is seen in locations within 1.6 km of TAPS: for example Ghivoli village registered an excess of 9.3 mR yr -1 over the natural background. The quarterly background values indicate minor temporal and spatial variations which can be attributed to changes in natural as well as stack released radioactivity. (author)

  10. Risk Factors Associated with the Choice to Drink Bottled Water and Tap Water in Rural Saskatchewan

    Directory of Open Access Journals (Sweden)

    Lianne McLeod

    2014-01-01

    Full Text Available A cross-sectional study investigated risk factors associated with choices to drink bottled water and tap water in rural Saskatchewan. Of 7,500 anonymous postal questionnaires mailed out, 2,065 responses were analyzed using generalized linear mixed models. Those who reported a water advisory (p < 0.001 or living in the area for £10 years (p = 0.01 were more likely to choose bottled water. Those who reported tap water was not safe to drink were more likely to choose bottled water, an effect greater for those who had no aesthetic complaints (p ≤ 0.001, while those with aesthetic complaints were more likely to choose bottled water if they believed the water was safe (p < 0.001. Respondents who treated their water and did not use a community supply were more likely to choose bottled water (p < 0.001, while those who did not treat their water were more likely to choose bottled water regardless of whether a community supply was used (p < 0.001. A similar pattern of risk factors was associated with a decreased likelihood of consuming tap water daily; however, the use of a community water supply was not significant. Understanding the factors involved in drinking water choices could inform public health education efforts regarding water management in rural areas.

  11. Yeasts and filamentous fungi in bottled mineral water and tap water from municipal supplies

    Directory of Open Access Journals (Sweden)

    Mirian Ueda Yamaguchi

    2007-01-01

    Full Text Available The main objective of this study was to analyse the occurrence of yeasts and filamentous fungi in drinking water as well as to investigate their correlation with the indicator bacteria of faecal pollution. Yeasts were detected in 36.6% and 11.6% of the bottled mineral on water dispensers and tap water samples from municipal system, respectively. Twenty-one (35.0% of bottled mineral water and two (3.3% of tap water samples were positive for filamentous fungi. For bottled mineral water 12 (20.0% of 60 samples were positive for total coliform, compared with 3(5.0%out of 60 samples from tap water. The mineral water from dispensers was more contaminated than tap water. Strains belonging to the genera Candida identified to the species level were C. parapsilosis, C. glabrata and C. albicans. Thus, bottled mineral water from water dispensers and tap water could be considered a possible transmission route for filamentous fungi and yeasts, and could constitute a potential health hazard, mainly to immunocompromised indivuals.O principal objetivo do presente estudo foi avaliar a prevalência de leveduras e fungos filamentosos em água potável, bem como investigar suas correlações com bactérias indicadoras de contaminação fecal. Leveduras foram detectadas em 36,6% e 11,6% das amostras de água mineral de garrafão em dispensadores de água e água de torneira do sistema municipal, respectivamente. Vinte e uma (35,5% das amostras de água mineral de garrafão e duas (3,3% das amostras de água de torneira foram positivas para fungos filamentosos. Para água mineral de garrafão, 12 (20.0% das 60 amostras foram positivas para coliforme total, comparado com 3 (5.0% das 60 amostras de água de torneira. A água coletada de garrafões de água mineral dos dispensadores foi marcadamente mais contaminada que as amostras de água de torneira. Candida spp identificadas ao nível de espécie foram C. parapsilosis, C. glabrata e C. albicans. Como está sendo

  12. The Effect of Spinal Tap Test on Different Sensory Modalities of Postural Stability in Idiopathic Normal Pressure Hydrocephalus

    Directory of Open Access Journals (Sweden)

    Katrin Abram

    2016-09-01

    Full Text Available Background/Aims: Postural instability in patients with normal pressure hydrocephalus (NPH is a most crucial symptom leading to falls with secondary complications. The aim of the current study was to evaluate the therapeutic effect of spinal tap on postural stability in these patients. Methods: Seventeen patients with clinical symptoms of NPH were examined using gait scale, computerized dynamic posturography (CDP, and neuropsychological assessment. Examinations were done before and after spinal tap test. Results: The gait score showed a significant improvement 24 h after spinal tap test in all subtests and in the sum score (p Conclusion: Postural stability in NPH is predominantly affected by deficient vestibular functions, which did not improve after spinal tap test. Conditions which improved best were mainly independent from visual control and are based on proprioceptive functions.

  13. Thermodynamic and structural studies of mixed monolayers: Mutual mixing of DPPC and DPPG with DoTAP at the air-water interface

    International Nuclear Information System (INIS)

    Panda, Amiya Kumar; Vasilev, Krasimir; Orgeig, Sandra; Prestidge, Clive A.

    2010-01-01

    Phospholipid monomolecular films at the air-water interface are useful model membranes to understand miscibility among various components. Surface pressure (π)-area (A) isotherms of pure and mixed monolayers of dioleoyltrimethylammonium propane (DoTAP)-dipalmitoylphosphatidylcholine (DPPC) and DoTAP-dipalmitoyphosphatidylglycerol (DPPG) were constructed using a surface balance. DPPC and DPPG produced isotherms as expected and reported earlier. DoTAP, an unsaturated lipid, demonstrated a continuous π-A isotherm. Associative interactions were identified in DPPC-DoTAP mixtures compared to the pure components, while DPPG-DoTAP mixtures showed repulsive interaction up to an equimolar ratio. Compression moduli of the monolayers revealed that DPPC-DoTAP mixtures had increasing stability with increasing surface pressure, but addition of DoTAP to DPPG showed instability at low and intermediate concentrations. In both cases increased stability was returned at higher X DoTAP values and surface pressures. Lipid monolayer film thickness values, determined on a gold coated glass substrate by surface plasmon resonance spectroscopy (SPR), indicated a systematic change in height profile for DPPC-DoTAP mixtures with increasing X DoTAP . However, DPPG-DoTAP mixed monolayer systems demonstrated a biphasic response. The SPR data were in excellent agreement with our interpretation of the structure of solid supported lipid monolayers.

  14. Thermodynamic and structural studies of mixed monolayers: Mutual mixing of DPPC and DPPG with DoTAP at the air-water interface

    Energy Technology Data Exchange (ETDEWEB)

    Panda, Amiya Kumar, E-mail: akpanda1@yahoo.com [Department of Chemistry, University of North Bengal, Darjeeling-734 013, West Bengal (India); Vasilev, Krasimir [Mawson Institute for Advanced Manufacturing, Mawson Lakes, University of South Australia, SA-5095 (Australia); Orgeig, Sandra [Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5000 (Australia); Prestidge, Clive A. [Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095 (Australia)

    2010-05-10

    Phospholipid monomolecular films at the air-water interface are useful model membranes to understand miscibility among various components. Surface pressure ({pi})-area (A) isotherms of pure and mixed monolayers of dioleoyltrimethylammonium propane (DoTAP)-dipalmitoylphosphatidylcholine (DPPC) and DoTAP-dipalmitoyphosphatidylglycerol (DPPG) were constructed using a surface balance. DPPC and DPPG produced isotherms as expected and reported earlier. DoTAP, an unsaturated lipid, demonstrated a continuous {pi}-A isotherm. Associative interactions were identified in DPPC-DoTAP mixtures compared to the pure components, while DPPG-DoTAP mixtures showed repulsive interaction up to an equimolar ratio. Compression moduli of the monolayers revealed that DPPC-DoTAP mixtures had increasing stability with increasing surface pressure, but addition of DoTAP to DPPG showed instability at low and intermediate concentrations. In both cases increased stability was returned at higher X{sub DoTAP} values and surface pressures. Lipid monolayer film thickness values, determined on a gold coated glass substrate by surface plasmon resonance spectroscopy (SPR), indicated a systematic change in height profile for DPPC-DoTAP mixtures with increasing X{sub DoTAP}. However, DPPG-DoTAP mixed monolayer systems demonstrated a biphasic response. The SPR data were in excellent agreement with our interpretation of the structure of solid supported lipid monolayers.

  15. The PP2A Regulatory Subunit Tap46, a Component of the TOR Signaling Pathway, Modulates Growth and Metabolism in Plants[W

    Science.gov (United States)

    Ahn, Chang Sook; Han, Jeong-A; Lee, Ho-Seok; Lee, Semi; Pai, Hyun-Sook

    2011-01-01

    Tap42/α4, a regulatory subunit of protein phosphatase 2A, is a downstream effector of the target of rapamycin (TOR) protein kinase, which regulates cell growth in coordination with nutrient and environmental conditions in yeast and mammals. In this study, we characterized the functions and phosphatase regulation of plant Tap46. Depletion of Tap46 resulted in growth arrest and acute plant death with morphological markers of programmed cell death. Tap46 interacted with PP2A and PP2A-like phosphatases PP4 and PP6. Tap46 silencing modulated cellular PP2A activities in a time-dependent fashion similar to TOR silencing. Immunoprecipitated full-length and deletion forms of Arabidopsis thaliana TOR phosphorylated recombinant Tap46 protein in vitro, supporting a functional link between Tap46 and TOR. Tap46 depletion reproduced the signature phenotypes of TOR inactivation, such as dramatic repression of global translation and activation of autophagy and nitrogen mobilization, indicating that Tap46 may act as a positive effector of TOR signaling in controlling those processes. Additionally, Tap46 silencing in tobacco (Nicotiana tabacum) BY-2 cells caused chromatin bridge formation at anaphase, indicating its role in sister chromatid segregation. These findings suggest that Tap46, in conjunction with associated phosphatases, plays an essential role in plant growth and development as a component of the TOR signaling pathway. PMID:21216945

  16. Ambulatory circadian monitoring (ACM) based on thermometry, motor activity and body position (TAP): a comparison with polysomnography.

    Science.gov (United States)

    Ortiz-Tudela, Elisabet; Martinez-Nicolas, Antonio; Albares, Javier; Segarra, Francesc; Campos, Manuel; Estivill, Eduard; Rol, Maria Angeles; Madrid, Juan Antonio

    2014-03-14

    An integrated variable based on the combination of wrist Temperature, motor Activity and body Position (TAP) was previously developed at our laboratory to evaluate the functioning of the circadian system and sleep-wake rhythm under ambulatory conditions. However, the reliability of TAP needed to be validated with polysomnography (PSG). 22 subjects suffering from sleep disorders were monitored for one night with a temperature sensor (iButton), an actimeter (HOBO) and exploratory PSG. Mean waveforms, sensitivity (SE), specificity (SP), agreement rates (AR) and comparisons between TAP and sleep stages were studied. The TAP variable was optimized for SE, SP and AR with respect to each individual variable (SE: 92%; SP: 78%; AR: 86%). These results improved upon estimates previously published for actigraphy. Furthermore, TAP values tended to decrease as sleep depth increased, reaching the lowest point at phase 3. Finally, TAP estimates for sleep latency (SL: 37±9 min), total sleep time (TST: 367±13 min), sleep efficiency (SE: 86.8±1.9%) and number of awakenings (NA>5 min: 3.3±.4) were not significantly different from those obtained with PSG (SL: 29±4 min; SE: 89.9±1.8%; NA>5 min: 2.3±.4), despite the heterogeneity of the sleep pathologies monitored. The TAP variable is a novel measurement for evaluating circadian system status and sleep-wake rhythms with a level of reliability better to that of actigraphy. Furthermore, it allows the evaluation of a patient's sleep-wake rhythm in his/her normal home environment, and at a much lower cost than PSG. Future studies in specific pathologies would verify the relevance of TAP in those conditions. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Spatial and statistical methods for correlating the interaction between groundwater contamination and tap water exposure in karst regions

    Science.gov (United States)

    Padilla, I. Y.; Rivera, V. L.; Macchiavelli, R. E.; Torres Torres, N. I.

    2016-12-01

    Groundwater systems in karst regions are highly vulnerable to contamination and have an enormous capacity to store and rapidly convey pollutants to potential exposure zones over long periods of time. Contaminants in karst aquifers used for drinking water purposes can, therefore, enter distributions lines and the tap water point of use. This study applies spatial and statistical analytical methods to assess potential correlations between contaminants in a karst groundwater system in northern Puerto Rico and exposure in the tap water. It focuses on chlorinated volatile organic compounds (CVOC) and phthalates because of their ubiquitous presence in the environment and the potential public health impacts. The work integrates historical data collected from regulatory agencies and current field measurements involving groundwater and tap water sampling and analysis. Contaminant distributions and cluster analysis is performed with Geographic Information System technology. Correlations between detection frequencies and contaminants concentration in source groundwater and tap water point of use are assessed using Pearson's Chi Square and T-Test analysis. Although results indicate that correlations are contaminant-specific, detection frequencies are generally higher for total CVOC in groundwater than tap water samples, but greater for phthalates in tap water than groundwater samples. Spatial analysis shows widespread distribution of CVOC and phthalates in both groundwater and tap water, suggesting that contamination comes from multiple sources. Spatial correlation analysis indicates that association between tap water and groundwater contamination depends on the source and type of contaminants, spatial location, and time. Full description of the correlations may, however, need to take into consideration variable anthropogenic interventions.

  18. The supply and demand of wine-on-tap in the United States: An examination of perceptions and experiences

    OpenAIRE

    Nuebling, Michaela Andrea

    2015-01-01

    The purpose of the present study was to investigate the perceptions and early experiences associated with a recent trend in the United States' foodservice and wine industry: wine-on-tap. Three study populations were investigated: wine consumers, restaurant and winery professionals. Contrary to expectations driven by literature and the diffusion of other wine product innovations, American wine consumers showed interest in trying wine-on-tap, stating that the main reason for non-adoption was li...

  19. A Study of Tapping by the Unaffected Finger of Patients Presenting with Central and Peripheral Nerve Damage

    OpenAIRE

    Zhang, Lingli; Han, Xiuying; Li, Peihong; Liu, Yang; Zhu, Yulian; Zou, Jun; Yu, Zhusheng

    2015-01-01

    Aim Whether the unaffected function of the hand of patients presenting with nerve injury is affected remains inconclusive. We aimed to evaluate whether there are differences in finger tapping following central or peripheral nerve injury compared with the unaffected hand and the ipsilateral hand of a healthy subject. Methods Thirty right brain stroke patients with hemiplegia, 30 left arm peripheral nerve injury cases, and 60 healthy people were selected. We tested finger tapping of ...

  20. A Study of Tapping by the Unaffected Finger of Patients Presenting with Central and Peripheral Nerve Damage

    OpenAIRE

    Lingli eZhang; Xiuying eHan; peihong eli; yang eliu; yulian ezhu; zhusheng eyu

    2015-01-01

    Aim: Whether the unaffected function of the hand of patients presenting with nerve injury is affected remains inconclusive. We aimed to evaluate whether there are differences in finger tapping following central or peripheral nerve injury compared with the unaffected hand and the ipsilateral hand of a healthy subject.Methods: 30 right brain stroke patients with hemiplegia, 30 left arm peripheral nerve injury cases and 60 healthy people were selected. We tested finger tapping of the right hands...

  1. Control of bacterial contamination of washbasin taps and output water using Ecasol: a one-year study.

    LENUS (Irish Health Repository)

    Boyle, M A

    2012-04-01

    Contaminated washbasin taps and output water are an important source of bacteria that may cause nosocomial infection. A five-week pretreatment study of hot and cold water from 15 washbasin taps at Dublin Dental Hospital showed consistently heavy contamination by aerobic heterotrophic bacteria: mean bacterial counts of 482.5 [standard deviation (SD) 293] colony-forming units (cfu)\\/mL and 5022 (SD 4322) cfu\\/mL, respectively.

  2. Age-related changes in the bimanual advantage and in brain oscillatory activity during tapping movements suggest a decline in processing sensory reafference.

    Science.gov (United States)

    Sallard, Etienne; Spierer, Lucas; Ludwig, Catherine; Deiber, Marie-Pierre; Barral, Jérôme

    2014-02-01

    Deficits in the processing of sensory reafferences have been suggested as accounting for age-related decline in motor coordination. Whether sensory reafferences are accurately processed can be assessed based on the bimanual advantage in tapping: because of tapping with an additional hand increases kinesthetic reafferences, bimanual tapping is characterized by a reduced inter-tap interval variability than unimanual tapping. A suppression of the bimanual advantage would thus indicate a deficit in sensory reafference. We tested whether elderly indeed show a reduced bimanual advantage by measuring unimanual (UM) and bimanual (BM) self-paced tapping performance in groups of young (n = 29) and old (n = 27) healthy adults. Electroencephalogram was recorded to assess the underlying patterns of oscillatory activity, a neurophysiological mechanism advanced to support the integration of sensory reafferences. Behaviorally, there was a significant interaction between the factors tapping condition and age group at the level of the inter-tap interval variability, driven by a lower variability in BM than UM tapping in the young, but not in the elderly group. This result indicates that in self-paced tapping, the bimanual advantage is absent in elderly. Electrophysiological results revealed an interaction between tapping condition and age group on low beta band (14-20 Hz) activity. Beta activity varied depending on the tapping condition in the elderly but not in the young group. Source estimations localized this effect within left superior parietal and left occipital areas. We interpret our results in terms of engagement of different mechanisms in the elderly depending on the tapping mode: a 'kinesthetic' mechanism for UM and a 'visual imagery' mechanism for BM tapping movement.

  3. System Efficiency of a Tap Transformer Based Grid Connection Topology Applied on a Direct Driven Generator for Wind Power

    Directory of Open Access Journals (Sweden)

    Senad Apelfröjd

    2014-01-01

    Full Text Available Results from experiments on a tap transformer based grid connection system for a variable speed vertical axis wind turbine are presented. The tap transformer based system topology consists of a passive diode rectifier, DC-link, IGBT inverter, LCL-filter, and tap transformer. Full range variable speed operation is enabled by using the different step-up ratios of a tap transformer. Simulations using MATLAB/Simulink have been performed in order to study the behavior of the system. A full experimental set up of the system has been used in the laboratory study, where a clone of the on-site generator was driven by an induction motor and the system was connected to a resistive load to better evaluate the performance. Furthermore, the system is run and evaluated for realistic wind speeds and variable speed operation. For a more complete picture of the system performance, a case study using real site Weibull parameters is done, comparing different tap selection options. The results show high system efficiency at nominal power and an increase in overall power output for full tap operation in comparison with the base case, a standard transformer. In addition, the loss distribution at different wind speeds is shown, which highlights the dominant losses at low and high wind speeds. Finally, means for further increasing the overall system efficiency are proposed.

  4. System efficiency of a tap transformer based grid connection topology applied on a direct driven generator for wind power.

    Science.gov (United States)

    Apelfröjd, Senad; Eriksson, Sandra

    2014-01-01

    Results from experiments on a tap transformer based grid connection system for a variable speed vertical axis wind turbine are presented. The tap transformer based system topology consists of a passive diode rectifier, DC-link, IGBT inverter, LCL-filter, and tap transformer. Full range variable speed operation is enabled by using the different step-up ratios of a tap transformer. Simulations using MATLAB/Simulink have been performed in order to study the behavior of the system. A full experimental set up of the system has been used in the laboratory study, where a clone of the on-site generator was driven by an induction motor and the system was connected to a resistive load to better evaluate the performance. Furthermore, the system is run and evaluated for realistic wind speeds and variable speed operation. For a more complete picture of the system performance, a case study using real site Weibull parameters is done, comparing different tap selection options. The results show high system efficiency at nominal power and an increase in overall power output for full tap operation in comparison with the base case, a standard transformer. In addition, the loss distribution at different wind speeds is shown, which highlights the dominant losses at low and high wind speeds. Finally, means for further increasing the overall system efficiency are proposed.

  5. System Efficiency of a Tap Transformer Based Grid Connection Topology Applied on a Direct Driven Generator for Wind Power

    Science.gov (United States)

    2014-01-01

    Results from experiments on a tap transformer based grid connection system for a variable speed vertical axis wind turbine are presented. The tap transformer based system topology consists of a passive diode rectifier, DC-link, IGBT inverter, LCL-filter, and tap transformer. Full range variable speed operation is enabled by using the different step-up ratios of a tap transformer. Simulations using MATLAB/Simulink have been performed in order to study the behavior of the system. A full experimental set up of the system has been used in the laboratory study, where a clone of the on-site generator was driven by an induction motor and the system was connected to a resistive load to better evaluate the performance. Furthermore, the system is run and evaluated for realistic wind speeds and variable speed operation. For a more complete picture of the system performance, a case study using real site Weibull parameters is done, comparing different tap selection options. The results show high system efficiency at nominal power and an increase in overall power output for full tap operation in comparison with the base case, a standard transformer. In addition, the loss distribution at different wind speeds is shown, which highlights the dominant losses at low and high wind speeds. Finally, means for further increasing the overall system efficiency are proposed. PMID:25258733

  6. Removal of Fe(II) from tap water by electrocoagulation technique

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, D.; Solanki, H. [Department of Chemical Engineering, Indian Institute of Technology, Guwahati 781039 (India); Purkait, M.K. [Department of Chemical Engineering, Indian Institute of Technology, Guwahati 781039 (India)], E-mail: mihir@iitg.ernet.in

    2008-06-30

    Electrocoagulation (EC) is a promising electrochemical technique for water treatment. In this work electrocoagulation (with aluminum as electrodes) was studied for iron Fe(II) removal from aqueous medium. Different concentration of Fe(II) solution in tap water was considered for the experiment. During EC process, various amorphous aluminum hydroxides complexes with high sorption capacity were formed. The removal of Fe(II) was consisted of two principal steps; (a) oxidation of Fe(II) to Fe(III) and (b) subsequent removal of Fe(III) by the freshly formed aluminum hydroxides complexes by adsorption/surface complexation followed by precipitation. Experiments were carried out with different current densities ranging from 0.01 to 0.04 A/m{sup 2}. It was observed that the removal of Fe(II) increases with current densities. Inter electrode distance was varied from 0.005 to 0.02 m and was found that least inter electrode distance is suitable in order to achieve higher Fe(II) removal. Other parameters such as conductivity, pH and salt concentration were kept constant as per tap water quality. Satisfactory iron removal of around 99.2% was obtained at the end of 35 min of operation from the initial concentration of 25 mg/L Fe(II). Iron concentration in the solution was determined using Atomic absorption spectrophotometer. By products obtained from the electrocoagulation bath were analyzed by SEM image and corresponding elemental analysis (EDAX). Cost estimation for the electrocoagulation was adopted and explained well. Up to 15 mg/L of initial Fe(II) concentration, the optimum total cost was 6.05 US$/m{sup 3}. The EC process for removing Fe(II) from tap water is expected to be adaptable for household use.

  7. Removal of Fe(II) from tap water by electrocoagulation technique

    International Nuclear Information System (INIS)

    Ghosh, D.; Solanki, H.; Purkait, M.K.

    2008-01-01

    Electrocoagulation (EC) is a promising electrochemical technique for water treatment. In this work electrocoagulation (with aluminum as electrodes) was studied for iron Fe(II) removal from aqueous medium. Different concentration of Fe(II) solution in tap water was considered for the experiment. During EC process, various amorphous aluminum hydroxides complexes with high sorption capacity were formed. The removal of Fe(II) was consisted of two principal steps; (a) oxidation of Fe(II) to Fe(III) and (b) subsequent removal of Fe(III) by the freshly formed aluminum hydroxides complexes by adsorption/surface complexation followed by precipitation. Experiments were carried out with different current densities ranging from 0.01 to 0.04 A/m 2 . It was observed that the removal of Fe(II) increases with current densities. Inter electrode distance was varied from 0.005 to 0.02 m and was found that least inter electrode distance is suitable in order to achieve higher Fe(II) removal. Other parameters such as conductivity, pH and salt concentration were kept constant as per tap water quality. Satisfactory iron removal of around 99.2% was obtained at the end of 35 min of operation from the initial concentration of 25 mg/L Fe(II). Iron concentration in the solution was determined using Atomic absorption spectrophotometer. By products obtained from the electrocoagulation bath were analyzed by SEM image and corresponding elemental analysis (EDAX). Cost estimation for the electrocoagulation was adopted and explained well. Up to 15 mg/L of initial Fe(II) concentration, the optimum total cost was 6.05 US$/m 3 . The EC process for removing Fe(II) from tap water is expected to be adaptable for household use

  8. Inorganic chemical quality of European tap-water: 1. Distribution of parameters and regulatory compliance

    International Nuclear Information System (INIS)

    Banks, David; Birke, Manfred; Flem, Belinda; Reimann, Clemens

    2015-01-01

    Highlights: • A pan-European survey comprises >60 inorganic parameters in 579 tap water samples. • Compliance with standards for inorganic parameters is good (>99% in EU states). • Around 1% non-compliance is observed for arsenic and 0.2% for uranium. • No sample of water contained nitrate in excess of 45 mg/L. • A weak co-variation in Cu and Pb could indicate derivation from plumbing. - Abstract: 579 tap water samples were collected at the European scale and analysed in a single laboratory for more than 60 parameters. This dataset is evaluated here in terms of the statistical distribution of the analysed parameters and compliance with EU and international drinking water regulations. For most parameters a 99% (or better) degree of compliance was achieved. Among the parameters with the higher rates of non-compliance are: arsenic (1% non-compliance in EU member states, 1.6% when samples from non-EU states are also considered) and sodium (0.6%/1.0%). The decision by the WHO to raise its provisional guideline from 15 μg/L (WHO, 2004) to 30 μg/L (WHO, 2011) has reduced non-compliance for uranium from 1.0% to 0.2%. Despite the fact that tap water (i.e. presumed treated water) was collected, many observations can still be interpreted in terms of hydrogeochemical processes. The dataset demonstrates the potential value of very cost-effective, low-density sampling approaches at a continental (European) scale

  9. Evaluation of sea water chlorine demand in condenser cooling water at TAPS 1 and 2

    International Nuclear Information System (INIS)

    Papachan, Deepa; Gupta, P.K.; Patil, D.P.; Save, C.B.; Anilkumar, K.R.

    2008-01-01

    To prevent microbiological growth in the condenser tubes, condenser cooling water chlorination is very important. For effective chlorination, chlorine dose rate and frequency of dosing has to be determined on the basis of sea water chlorine demand. TAPS 1 and 2 is located near Arabian sea and draws water from this sea for its condenser cooling. The present practice of chlorine dosing at TAPS 1 and 2, based on the analysis carried out by GE in 1969, is 2500 kg/day/CWpump and 90 kg/day/SSWpump for a contact period of 25 minutes. Normal frequency of dosing is once per 8 hour and booster dose is once in a week at the same rate for 1 hour. The criteria of effective chlorination is to get residual chlorine of 2-3 ppm at the condenser water box outlet during chlorination at water box inlet/CW pump suction header in the recommended dose rate. The other option of chlorination was continuous dosing to get 0.5 ppm residual chlorine. This option has its own limitations as it is more expensive and also that micro organisms get immune to chlorine eventually due to continuous dosing. Nevertheless higher chlorine dosing is detrimental to AI-brass condenser tubes. Therefore the second option was not adopted at TAPS 1 and 2. Tarapur Atomic Power Station-1 is in the process of replacement of condenser tubes due to frequent condenser tube failures in the recent years. It was essential to analyse the present sea water chlorine demand and re-determine the chlorine dose rate because of development of industries under Maharashtra Industrial Development Corporation (MIDC) and simultaneous population growth around this area over a period of three decades. This paper discusses the experimental observations regarding significant change in sea water chlorine demand over this period and the effect of seasonal changes on sea water chlorine demand. (author)

  10. Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway

    Science.gov (United States)

    Ahn, Chang Sook; Ahn, Hee-Kyung; Pai, Hyun-Sook

    2015-01-01

    Tap46, a regulatory subunit of protein phosphatase 2A (PP2A), plays an essential role in plant growth and development through a functional link with the Target of Rapamycin (TOR) signalling pathway. Here, we have characterized the molecular mechanisms behind a gain-of-function phenotype of Tap46 and its relationship with TOR to gain further insights into Tap46 function in plants. Constitutive overexpression of Tap46 in Arabidopsis resulted in overall growth stimulation with enlarged organs, such as leaves and siliques. Kinematic analysis of leaf growth revealed that increased cell size was mainly responsible for the leaf enlargement. Tap46 overexpression also enhanced seed size and viability under accelerated ageing conditions. Enhanced plant growth was also observed in dexamethasone (DEX)-inducible Tap46 overexpression Arabidopsis lines, accompanied by increased cellular activities of nitrate-assimilating enzymes. DEX-induced Tap46 overexpression and Tap46 RNAi resulted in increased and decreased phosphorylation of S6 kinase (S6K), respectively, which is a sensitive indicator of endogenous TOR activity, and Tap46 interacted with S6K in planta based on bimolecular fluorescence complementation and co-immunoprecipitation. Furthermore, inactivation of TOR by estradiol-inducible RNAi or rapamycin treatment decreased Tap46 protein levels, but increased PP2A catalytic subunit levels. Real-time quantitative PCR analysis revealed that Tap46 overexpression induced transcriptional modulation of genes involved in nitrogen metabolism, ribosome biogenesis, and lignin biosynthesis. These findings suggest that Tap46 modulates plant growth as a positive effector of the TOR signalling pathway and Tap46/PP2Ac protein abundance is regulated by TOR activity. PMID:25399018

  11. Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway.

    Science.gov (United States)

    Ahn, Chang Sook; Ahn, Hee-Kyung; Pai, Hyun-Sook

    2015-02-01

    Tap46, a regulatory subunit of protein phosphatase 2A (PP2A), plays an essential role in plant growth and development through a functional link with the Target of Rapamycin (TOR) signalling pathway. Here, we have characterized the molecular mechanisms behind a gain-of-function phenotype of Tap46 and its relationship with TOR to gain further insights into Tap46 function in plants. Constitutive overexpression of Tap46 in Arabidopsis resulted in overall growth stimulation with enlarged organs, such as leaves and siliques. Kinematic analysis of leaf growth revealed that increased cell size was mainly responsible for the leaf enlargement. Tap46 overexpression also enhanced seed size and viability under accelerated ageing conditions. Enhanced plant growth was also observed in dexamethasone (DEX)-inducible Tap46 overexpression Arabidopsis lines, accompanied by increased cellular activities of nitrate-assimilating enzymes. DEX-induced Tap46 overexpression and Tap46 RNAi resulted in increased and decreased phosphorylation of S6 kinase (S6K), respectively, which is a sensitive indicator of endogenous TOR activity, and Tap46 interacted with S6K in planta based on bimolecular fluorescence complementation and co-immunoprecipitation. Furthermore, inactivation of TOR by estradiol-inducible RNAi or rapamycin treatment decreased Tap46 protein levels, but increased PP2A catalytic subunit levels. Real-time quantitative PCR analysis revealed that Tap46 overexpression induced transcriptional modulation of genes involved in nitrogen metabolism, ribosome biogenesis, and lignin biosynthesis. These findings suggest that Tap46 modulates plant growth as a positive effector of the TOR signalling pathway and Tap46/PP2Ac protein abundance is regulated by TOR activity. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  12. Studies of η' (ω) mesons with the crystal ball/TAPS setup at MAMI

    Energy Technology Data Exchange (ETDEWEB)

    Adlarson, Patrik [Institut fuer Kernphysik, Johannes Gutenberg Universitaet, Mainz (Germany); Collaboration: A2-Collaboration

    2015-07-01

    Precision studies of light meson decays are used to investigate a wide range of topics related to fundamental aspects of hadron physics. In particular, η' decays allow for tests of such diverse topics as ππ scattering lengths, the SU(3) singlet-octet mixing angle, quark mass differences and light-by-light contribution to the anomalous magnetic moment of the muon. Recently, a large statistics sample of η'(ω) mesons have been produced and collected with the Crystal Ball/TAPS setup at MAMI. An overview of the physics motivation, the experimental setup and preliminary results from the ongoing analyses are presented.

  13. Assessment of drinking water quality at the tap using fluorescence spectroscopy

    DEFF Research Database (Denmark)

    Heibati, Masoumeh; Stedmon, Colin A; Stenroth, Karolina

    2017-01-01

    Treated drinking water may become contaminated while travelling in the distribution system on the way to consumers. Elevated dissolved organic matter (DOM) at the tap relative to the water leaving the treatment plant is a potential indicator of contamination, and can be measured sensitively......, relationships between DOM optical properties, microbial indicator organisms and trace elements were investigated for households connected to a biologically-stable drinking water distribution system. Across the network, humic-like fluorescence intensities showed limited variation (RSD = 3.5-4.4%), with half...

  14. The TApIR experiment. IR absorption spectra of liquid hydrogen isotopologues

    International Nuclear Information System (INIS)

    Groessle, Robin

    2015-01-01

    The scope of the thesis is the infrared absorption spectroscopy of liquid hydrogen isotopologues with the tritium absorption infrared spectroscopy (TApIR) experiment at the tritium laboratory Karlsruhe (TLK). The calibration process from the sample preparation to the reference measurements are described. A further issue is the classical evaluation of FTIR absorption spectra and the extension using the rolling circle filter (RCF) including the effects on statistical and systematical errors. The impact of thermal and nuclear spin temperature on the IR absorption spectra is discussed. An empirical based modeling for the IR absorption spectra of liquid hydrogen isotopologues is performed.

  15. System for sampling liquids in small jugs obturated by screwed taps

    International Nuclear Information System (INIS)

    Besnier, J.

    1995-01-01

    This invention describes a machine which samples automatically liquids in small jugs obturated by screwed taps. This device can be situated in an isolated room in order to work with radioactive liquids. The machine can be divided in three main parts: a module to catch the jug, in order to take and fix it, a module to open and to close it, and a module to sample. The later takes the liquid thanks to a suction device and puts it in a container, in order to analyse the sample. (TEC)

  16. Growth-supporting activity for Legionella pneumophila in tap water cultures and implication of hartmannellid amoebae as growth factors.

    Science.gov (United States)

    Wadowsky, R M; Butler, L J; Cook, M K; Verma, S M; Paul, M A; Fields, B S; Keleti, G; Sykora, J L; Yee, R B

    1988-11-01

    Photosynthetic cyanobacteria, heterotrophic bacteria, free-living amoebae, and ciliated protozoa may support growth of Legionella pneumophila. Studies were done with two tap water cultures (WS1 and WS2) containing L. pneumophila and associated microbiota to characterize growth-supporting activity and assess the relative importance of the microbiota in supporting multiplication of L. pneumophila. The water cultures were incubated in the dark at 35 degrees C. The growth-supporting factor(s) was separated from each culture by filtration through 1-micron-pore-size membrane filters. The retentate was then suspended in sterile tap water. Multiplication of L. pneumophila occurred when both the retentate suspension and the filtrate from either culture were inoculated into sterile tap water. L. pneumophila did not multiply in tap water inoculated with only the filtrate, even though filtration did not reduce the concentration of L. pneumophila or heterotrophic bacteria in either culture. Growth-supporting activity of the retentate suspension from WS1 was inactivated at 60 degrees C but unaffected at 0, 25, and 45 degrees C after 30-min incubations. Filtration experiments indicated that the growth-supporting factor(s) in WS1 was 2 to 5 micron in diameter. Ciliated protozoa were not detected in either culture. Hartmannellid amoebae were conclusively demonstrated in WS2 but not in WS1. L. pneumophila multiplied in tap water inoculated with the amoebae (10(3)/ml) and the 1-micron filtrate of WS2. No multiplication occurred in tap water inoculated with the filtrate only. Growth-supporting activity for L. pneumophila may be present in plumbing systems; hartmannellid amoebae appear to be important determinants of multiplication of L. pneumophila in some tap water cultures.

  17. Design and development of weld inspection manipulator for reactor pressure vessel of TAPS-1

    International Nuclear Information System (INIS)

    Chatterjee, H.; Singh, J.P.; Ranjon, R.; Kulkarni, M.P.; Patel, R.J.

    2013-01-01

    The reactor pressure vessel (RPV) of TAPS-1 BWR contains six longitudinal and four circumferential welds. Periodical in-service inspection of these weld joints has been a regulatory issue pending for long. In the 22 nd refuelling outage in July 2012 the inspection of L1-1, L1-2 longitudinal welds as well as their junctions with C1 circumferential weld were proposed to be done using ultrasonic technique. Approaching these welds from OD side of the RPV is a difficult and tedious task. Therefore it was decided to examine these welds from ID side of the RPV by filling the cavity with water and approaching the RPV from top. No technology was locally available to take the probes at a depth of 10-12 m under water. NPCIL approached RTD, BARC to develop an underwater manipulator to accomplish this task. RTD took up this work as a challenge and came out with the design of manipulator. The weld inspection manipulator (WIM) was fabricated on a war foot basis, tested and successfully implemented in the reactor for the first time in TAPS history. The entire activity was completed in three months time. This article gives the details of design, manufacturing, performance testing, qualification trials and implementation of WIM in the reactor. Ultrasonic testing techniques were developed by QAD, BARC which are not covered in this article. (author)

  18. Photovoltaic Hosting Capacity of Feeders with Reactive Power Control and Tap Changers

    Energy Technology Data Exchange (ETDEWEB)

    Ceylan, Oğuzhan; Paudyal, Sumit; Bhattarai, Bishnu P.; Myers, Kurt S.

    2017-06-01

    This paper proposes an algorithm to determine photovoltaic (PV) hosting capacity of power distribution networks as a function of number of PV injection nodes, reactive power support from the PVs, and the sub-station load tap changers (LTCs). In the proposed method, several minute by minute simulations are run based on randomly chosen PV injection nodes, daily PV output profiles, and daily load profiles from a pool of high-resolution realistic data set. The simulation setup is built using OpenDSS and MATLAB. The performance of the proposed method is investigated in the IEEE 123-node distribution feeder for multiple scenarios. The case studies are performed particularly for one, two, five and ten PV injection nodes, and looking at the maximum voltage deviations. Case studies show that the PV hosting capacity of the 123-node feeder greatly differs with the number of PV injection nodes. We have also observed that the PV hosting capacity increases with reactive power support and higher tap position of sub-station LTC.

  19. Assessment of macrofauna around Tarapur Atomic Power Station (TAPS), Maharashtra, India

    International Nuclear Information System (INIS)

    Kubal, Priti; Ambekar, Ajit; Prakash, Chandra; Sawant, Paramita B.; Pal, Asim K.; Lakra, W.S.; Baburajan, A.

    2015-01-01

    A study was carried out to observe the macrofaunal habitation in the coastal area of India's first commercial atomic power station at Tarapur, Maharashtra. Mostly macrobenthos are sedentary as well as sessile in nature; therefore, they are used as indicator organism to monitor health of marine ecosystem. The faunal record observed consisted of 25 groups with 16 different polychaete families dominated by nereidae, capitellidae and spionidae. Shannon wiener index (H') was highest at Varor for faunal groups (2.07) and polychaete families (2.89) and lowest at anthropogenically stressed Uchheli (faunal group -0.77 and polychaete family 1.94). These findings were further supported by dendrogram. Margalef's species richness was highest at Varor (fauna -1.93 and polychaete family -1.61) and lowest at Nandgoan (fauna-1.00 and polychaete family - 0.74) due to dominance of environmental bioindicators, polychaete (nereidae). Along with these observations, hydro-sedimentological parameters revealed comprehensive picture of community structure of macrobenthos and polychaetes families. The elevated water temperature was noticed at TAPS 3 and 4 (30.1 °C) which is under permissible limit (26-28°C ±7) accompanied by pH (7.0). Dissolved oxygen was lowest at Uchheli (4.1mgl -1 ) and maximum was observed at TAPS 1 and 2 area (7.5mgl -1 ). (author)

  20. Distractor Effect of Auditory Rhythms on Self-Paced Tapping in Chimpanzees and Humans

    Science.gov (United States)

    Hattori, Yuko; Tomonaga, Masaki; Matsuzawa, Tetsuro

    2015-01-01

    Humans tend to spontaneously align their movements in response to visual (e.g., swinging pendulum) and auditory rhythms (e.g., hearing music while walking). Particularly in the case of the response to auditory rhythms, neuroscientific research has indicated that motor resources are also recruited while perceiving an auditory rhythm (or regular pulse), suggesting a tight link between the auditory and motor systems in the human brain. However, the evolutionary origin of spontaneous responses to auditory rhythms is unclear. Here, we report that chimpanzees and humans show a similar distractor effect in perceiving isochronous rhythms during rhythmic movement. We used isochronous auditory rhythms as distractor stimuli during self-paced alternate tapping of two keys of an electronic keyboard by humans and chimpanzees. When the tempo was similar to their spontaneous motor tempo, tapping onset was influenced by intermittent entrainment to auditory rhythms. Although this effect itself is not an advanced rhythmic ability such as dancing or singing, our results suggest that, to some extent, the biological foundation for spontaneous responses to auditory rhythms was already deeply rooted in the common ancestor of chimpanzees and humans, 6 million years ago. This also suggests the possibility of a common attentional mechanism, as proposed by the dynamic attending theory, underlying the effect of perceiving external rhythms on motor movement. PMID:26132703

  1. Sustained negative BOLD response in human fMRI finger tapping task.

    Directory of Open Access Journals (Sweden)

    Yadong Liu

    Full Text Available In this work, we investigated the sustained negative blood oxygen level-dependent (BOLD response (sNBR using functional magnetic resonance imaging during a finger tapping task. We observed that the sNBR for this task was more extensive than has previously been reported. The cortical regions involved in sNBR are divided into the following three groups: frontal, somatosensory and occipital. By investigating the spatial structure, area, amplitude, and dynamics of the sNBR in comparison with those of its positive BOLD response (PBR counterpart, we made the following observations. First, among the three groups, the somatosensory group contained the greatest number of activated voxels and the fewest deactivated voxels. In addition, the amplitude of the sNBR in this group was the smallest among the three groups. Second, the onset and peak time of the sNBR are both larger than those of the PBR, whereas the falling edge time of the sNBR is less than that of the PBR. Third, the long distance between most sNBR foci and their corresponding PBR foci makes it unlikely that they share the same blood supply artery. Fourth, the couplings between the sNBR and its PBR counterpart are distinct among different regions and thus should be investigated separately. These findings imply that the origin of most sNBR foci in the finger-tapping task is much more likely to be neuronal activity suppression rather than "blood steal."

  2. Finger and foot tapping as alternative outcomes of upper and lower extremity function in multiple sclerosis.

    Science.gov (United States)

    Tanigawa, Makoto; Stein, Jason; Park, John; Kosa, Peter; Cortese, Irene; Bielekova, Bibiana

    2017-01-01

    While magnetic resonance imaging contrast-enhancing lesions represent an excellent screening tool for disease-modifying treatments in relapsing-remitting multiple sclerosis (RRMS), this biomarker is insensitive for testing therapies against compartmentalized inflammation in progressive multiple sclerosis (MS). Therefore, alternative sensitive outcomes are needed. Using machine learning, clinician-acquired disability scales can be combined with timed measures of neurological functions such as walking speed (e.g. 25-foot walk; 25FW) or fine finger movements (e.g. 9-hole peg test; 9HPT) into sensitive composite clinical scales, such as the recently developed combinatorial, weight-adjusted disability scale (CombiWISE). Ideally, these complementary simplified measurements of certain neurological functions could be performed regularly at patients' homes using smartphones. We asked whether tests amenable to adaptation to smartphone technology, such as finger and foot tapping have comparable sensitivity and specificity to current non-clinician-acquired disability measures. We observed that finger and foot tapping can differentiate RRMS and progressive MS in a cross-sectional study and can also measure yearly and two-year disease progression in the latter, with better power (based on z-scores) in comparison to currently utilized 9HPT and 25FW. Replacing the 9HPT and 25FW with simplified tests broadly adaptable to smartphone technology may enhance the power of composite scales for progressive MS.

  3. Involvement of Ethylene in the Latex Metabolism and Tapping Panel Dryness of Hevea brasiliensis

    Science.gov (United States)

    Putranto, Riza-Arief; Herlinawati, Eva; Rio, Maryannick; Leclercq, Julie; Piyatrakul, Piyanuch; Gohet, Eric; Sanier, Christine; Oktavia, Fetrina; Pirrello, Julien; Kuswanhadi; Montoro, Pascal

    2015-01-01

    Ethephon, an ethylene releaser, is used to stimulate latex production in Hevea brasiliensis. Ethylene induces many functions in latex cells including the production of reactive oxygen species (ROS). The accumulation of ROS is responsible for the coagulation of rubber particles in latex cells, resulting in the partial or complete stoppage of latex flow. This study set out to assess biochemical and histological changes as well as changes in gene expression in latex and phloem tissues from trees grown under various harvesting systems. The Tapping Panel Dryness (TPD) susceptibility of Hevea clones was found to be related to some biochemical parameters, such as low sucrose and high inorganic phosphorus contents. A high tapping frequency and ethephon stimulation induced early TPD occurrence in a high latex metabolism clone and late occurrence in a low latex metabolism clone. TPD-affected trees had smaller number of laticifer vessels compared to healthy trees, suggesting a modification of cambial activity. The differential transcript abundance was observed for twenty-seven candidate genes related to TPD occurrence in latex and phloem tissues for ROS-scavenging, ethylene biosynthesis and signalling genes. The predicted function for some Ethylene Response Factor genes suggested that these candidate genes should play an important role in regulating susceptibility to TPD. PMID:26247941

  4. Medida de autocontrol motor en tiradores de esgrima mediante el Tapping Test

    Directory of Open Access Journals (Sweden)

    Omar Estrada Contreras

    2013-01-01

    Full Text Available El Tapping Test es una prueba neurológica habitual en las evaluaciones de los equipos nacionales de Cuba. Nuestro objetivo fue medir el autocontrol motor con esta prueba y su respuesta psicofisiológica en deportistas de la selección nacional de esgrima de Cuba. Comparando dos versiones del Tapping Test: modo 1 (habitual de lápiz-papel y modo 2 (versión propuesta ejecutando acción técnica con el arma. Fueron 12 participantes (edadM = 22.19 años, DE = 3.50 años. Se utilizó un equipo de registro psicofisiológico inalámbrico (Biofeedback 2000. Los resultados, indican un autocontrol motor, siendo el modo 1 significativo F(1,10 = 44.29, p < .001; ya que la cantidad de toques o golpes fueron coherentes de acuerdo al ritmo de ejecución. El modo 2 tuvo una motilidad o aceleración significativa en las diferentes fases de la prueba F(1.58,15.8 = 8.14, p = .006, además mostró un mayor nivel de activación psicofisiológica. Este grupo de esgrimistas de alto nivel a pesar del incremento en la activación mostraron un autocontrol motor, ya que controlaron su movimiento de acuerdo al ritmo que se pedía (modo 1.

  5. Sustained negative BOLD response in human fMRI finger tapping task.

    Science.gov (United States)

    Liu, Yadong; Shen, Hui; Zhou, Zongtan; Hu, Dewen

    2011-01-01

    In this work, we investigated the sustained negative blood oxygen level-dependent (BOLD) response (sNBR) using functional magnetic resonance imaging during a finger tapping task. We observed that the sNBR for this task was more extensive than has previously been reported. The cortical regions involved in sNBR are divided into the following three groups: frontal, somatosensory and occipital. By investigating the spatial structure, area, amplitude, and dynamics of the sNBR in comparison with those of its positive BOLD response (PBR) counterpart, we made the following observations. First, among the three groups, the somatosensory group contained the greatest number of activated voxels and the fewest deactivated voxels. In addition, the amplitude of the sNBR in this group was the smallest among the three groups. Second, the onset and peak time of the sNBR are both larger than those of the PBR, whereas the falling edge time of the sNBR is less than that of the PBR. Third, the long distance between most sNBR foci and their corresponding PBR foci makes it unlikely that they share the same blood supply artery. Fourth, the couplings between the sNBR and its PBR counterpart are distinct among different regions and thus should be investigated separately. These findings imply that the origin of most sNBR foci in the finger-tapping task is much more likely to be neuronal activity suppression rather than "blood steal."

  6. Preference for tap, bottled, and recycled water: Relations to PTC taste sensitivity and personality.

    Science.gov (United States)

    Harmon, Daniel; Gauvain, Mary; Z Reisz; Arthur, Isaac; Story, S Drew

    2018-02-01

    This study investigated people's preferences for different water sources and factors that predict such preferences using a blind taste test. Water preferences of 143 participants for one name-brand bottled water, one groundwater-sourced tap water, and one indirect potable reuse (IDR) water were assessed. For predictors of water preference, we measured each participant's PTC taste sensitivity and assessed two personality traits (Neuroticism, Openness to Experience). We also explored participants' descriptions of each water source. Results indicate a preference for water treated with Reverse Osmosis (RO) (bottled and IDR water) over groundwater-sourced water, which had higher pH levels and lower concentrations of Ca and HCO 3 - . PTC taste sensitivity did not predict preferences, while Openness to Experience and Neuroticism predicted preference for IDR water. Positive relations between Openness to Experience and preferences for bottled and IDR water were moderated by gender and were stronger among females. Participants described water primarily by its taste and texture. Findings suggest that (1) tap water treated by RO is equally preferable to some bottled water, (2) personality traits may affect water preferences, and (3) prior findings of gender differences in preferences for bottled water may reflect personality characteristics. Efforts to increase acceptance for sustainable water alternatives, such as IDR, may be more successful by assuring consumers about taste and addressing personality traits that encourage or inhibit use. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Legionella species diversity and dynamics from surface reservoir to tap water: from cold adaptation to thermophily.

    Science.gov (United States)

    Lesnik, René; Brettar, Ingrid; Höfle, Manfred G

    2016-05-01

    Water samples of the Drinking Water Supply System (DWSS) of the city of Braunschweig were analysed for its Legionella species composition using genus-specific PCR amplicons and single-strand conformation polymorphism (SSCP) fingerprint analyses based on 16S rRNA genes. These analyses comprised the whole supply chain including raw water, treatment process and large-scale storage, and a seasonal study of finished drinking water sampled monthly from cold and hot tap water. Treatment of raw water had a major impact on Legionella species by reducing their diversity and abundances. The Legionella species composition of the tap water was highly distinct from that of both source waters. In cold water, 8-14 different phylotypes of Legionella (PTLs) were observed per sample with relative abundances ranging from >1% to 53%. In hot water, L. pneumophila was present during all seasons at high relative abundances (8-40%) accompanied by 5-14 other PTLs of which 6 PTLs were in common with cold water. This thermophilic Legionella community, including L. pneumophila, was able to grow in the hot water above 50 °C. Such thermophilic Legionella populations are of general relevance for drinking water management and public health, but also for the ecology and evolution of the genus Legionella.

  8. Concurrence of superconductivity and structure transition in Weyl semimetal TaP under pressure

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yufeng; Zhou, Yonghui; Guo, Zhaopeng; Han, Fei; Chen, Xuliang; Lu, Pengchao; Wang, Xuefei; An, Chao; Zhou, Ying; Xing, Jie; Du, Guan; Zhu, Xiyu; Yang, Huan; Sun, Jian; Yang, Zhaorong; Yang, Wenge; Mao, Ho-Kwang; Zhang, Yuheng; Wen, Hai-Hu

    2017-12-01

    Weyl semimetal defines a material with three-dimensional Dirac cones, which appear in pair due to the breaking of spatial inversion or time reversal symmetry. Superconductivity is the state of quantum condensation of paired electrons. Turning a Weyl semimetal into superconducting state is very important in having some unprecedented discoveries. In this work, by doing resistive measurements on a recently recognized Weyl semimetal TaP under pressures up to about 100 GPa, we show the concurrence of superconductivity and a structure transition at about 70 GPa. It is found that the superconductivity becomes more pronounced when decreasing pressure and retains when the pressure is completely released. High-pressure x-ray diffraction measurements also confirm the structure phase transition from I41md to P-6m2 at about 70 GPa. More importantly, ab-initial calculations reveal that the P-6m2 phase is a new Weyl semimetal phase and has only one set of Weyl points at the same energy level. Our discovery of superconductivity in TaP by high pressure will stimulate investigations on superconductivity and Majorana fermions in Weyl semimetals.

  9. High-resolution and large dynamic range nanomechanical mapping in tapping-mode atomic force microscopy

    International Nuclear Information System (INIS)

    Sahin, Ozgur; Erina, Natalia

    2008-01-01

    High spatial resolution imaging of material properties is an important task for the continued development of nanomaterials and studies of biological systems. Time-varying interaction forces between the vibrating tip and the sample in a tapping-mode atomic force microscope contain detailed information about the elastic, adhesive, and dissipative response of the sample. We report real-time measurement and analysis of the time-varying tip-sample interaction forces with recently introduced torsional harmonic cantilevers. With these measurements, high-resolution maps of elastic modulus, adhesion force, energy dissipation, and topography are generated simultaneously in a single scan. With peak tapping forces as low as 0.6 nN, we demonstrate measurements on blended polymers and self-assembled molecular architectures with feature sizes at 1, 10, and 500 nm. We also observed an elastic modulus measurement range of four orders of magnitude (1 MPa to 10 GPa) for a single cantilever under identical feedback conditions, which can be particularly useful for analyzing heterogeneous samples with largely different material components.

  10. Finger tapping movements of Parkinson's disease patients automatically rated using nonlinear delay differential equations.

    Science.gov (United States)

    Lainscsek, C; Rowat, P; Schettino, L; Lee, D; Song, D; Letellier, C; Poizner, H

    2012-03-01

    Parkinson's disease is a degenerative condition whose severity is assessed by clinical observations of motor behaviors. These are performed by a neurological specialist through subjective ratings of a variety of movements including 10-s bouts of repetitive finger-tapping movements. We present here an algorithmic rating of these movements which may be beneficial for uniformly assessing the progression of the disease. Finger-tapping movements were digitally recorded from Parkinson's patients and controls, obtaining one time series for every 10 s bout. A nonlinear delay differential equation, whose structure was selected using a genetic algorithm, was fitted to each time series and its coefficients were used as a six-dimensional numerical descriptor. The algorithm was applied to time-series from two different groups of Parkinson's patients and controls. The algorithmic scores compared favorably with the unified Parkinson's disease rating scale scores, at least when the latter adequately matched with ratings from the Hoehn and Yahr scale. Moreover, when the two sets of mean scores for all patients are compared, there is a strong (r = 0.785) and significant (p<0.0015) correlation between them.

  11. Torsional tapping atomic force microscopy for molecular resolution imaging of soft matter

    Science.gov (United States)

    Hobbs, Jamie; Mullin, Nic

    2012-02-01

    Despite considerable advances in image resolution on challenging, soft systems, a method for obtaining molecular resolution on `real' samples with significant surface roughness has remained elusive. Here we will show that a relatively new technique, torsional tapping AFM (TTAFM), is capable of imaging with resolution down to 3.7 Angrstrom on the surface of `bulk' polymer films [1]. In TTAFM T-shaped cantilevers are driven into torsional oscillation. As the tip is offset from the rotation axis this provides a tapping motion. Due to the high frequency and Q of the oscillation and relatively small increase in spring constant, improved cantilever dynamics and force sensitivity are obtained. As the tip offset from the torsional axis is relatively small (typically 25 microns), the optical lever sensitivity is considerably improved compared to flexural oscillation. Combined these give a reduction in noise floor by a factor of 12 just by changing the cantilever geometry. The ensuing low noise allows the use of ultra-sharp `whisker' tips with minimal blunting. As the cantilevers remain soft in the flexural axis, the force when imaging with error is also reduced, further protecting the tip. We will show that this combination allows routine imaging of the molecular structure of semicrystalline polymer films, including chain folds, loose loops and tie-chains in polyethylene, and the helical conformation of polypropylene within the crystal, using a standard, commercial AFM. [4pt] [1] N Mullin, JK Hobbs, PRL 107, 197801 (2011)

  12. Modality and Perceptual-Motor Experience Influence the Detection of Temporal Deviations in Tap Dance Sequences

    Directory of Open Access Journals (Sweden)

    Mauro Murgia

    2017-08-01

    Full Text Available Accurate temporal information processing is critically important in many motor activities within disciplines such as dance, music, and sport. However, it is still unclear how temporal information related to biological motion is processed by expert and non-expert performers. It is well-known that the auditory modality dominates the visual modality in processing temporal information of simple stimuli, and that experts outperform non-experts in biological motion perception. In the present study, we combined these two areas of research; we investigated how experts and non-experts detected temporal deviations in tap dance sequences, in the auditory modality compared to the visual modality. We found that temporal deviations were better detected in the auditory modality compared to the visual modality, and by experts compared to non-experts. However, post hoc analyses indicated that these effects were mainly due to performances obtained by experts in the auditory modality. The results suggest that the experience advantage is not equally distributed across the modalities, and that tap dance experience enhances the effectiveness of the auditory modality but not the visual modality when processing temporal information. The present results and their potential implications are discussed in both temporal information processing and biological motion perception frameworks.

  13. Transient TAP approach to investigate adsorption and diffusion of small alkanes in porous sulfated zirconia

    Energy Technology Data Exchange (ETDEWEB)

    Galinsky, M.; Breitkopf, C. [Technische Univ. Dresden (Germany). Inst. fuer Energietechnik

    2011-07-01

    Sulfated zirconias have attracted an interest as catalysts due to their ability to isomerize alkanes at low temperatures, e.g., under thermodynamically favored conditions. However, the fast deactivation during the reaction remains a problem. To improve the catalytic performance of such porous catalysts, it is necessary to understand all steps in the catalytic cycle, namely diffusion and adsorption in more detail. The transient TAP method was applied to investigate sorption and diffusion phenomena of different alkanes in three different morphologically structured sulfated zirconias to elucidate their catalytic performances in the n-butane isomerization. New theoretical models were developed to describe the experimental results of TAP single-pulse experiments. The application of these models to pulse response curves allowed the extraction of adsorption and desorption rate constants as well as diffusion coefficients. Via introducing a second sorption center, the new adsorption model is able to reproduce the sorption behavior for larger alkanes quantitatively better than former models, especially in the low-temperature region. Moreover, the heterogeneous distribution of active centers was taken into account. Temperature dependent measurements have been performed to calculate heats of adsorption for various alkanes at the two assumed adsorption sites. The impact of these values on the catalytic properties is discussed. With the help of the new diffusion model, the diffusion coefficients for the inter- and intrapellet volume could be determined. These values are used in a numerical simulation to check whether the reaction rate for the isomerization at the investigated sulfated zirconias is diffusion limited. (orig.)

  14. Distractor Effect of Auditory Rhythms on Self-Paced Tapping in Chimpanzees and Humans.

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    Yuko Hattori

    Full Text Available Humans tend to spontaneously align their movements in response to visual (e.g., swinging pendulum and auditory rhythms (e.g., hearing music while walking. Particularly in the case of the response to auditory rhythms, neuroscientific research has indicated that motor resources are also recruited while perceiving an auditory rhythm (or regular pulse, suggesting a tight link between the auditory and motor systems in the human brain. However, the evolutionary origin of spontaneous responses to auditory rhythms is unclear. Here, we report that chimpanzees and humans show a similar distractor effect in perceiving isochronous rhythms during rhythmic movement. We used isochronous auditory rhythms as distractor stimuli during self-paced alternate tapping of two keys of an electronic keyboard by humans and chimpanzees. When the tempo was similar to their spontaneous motor tempo, tapping onset was influenced by intermittent entrainment to auditory rhythms. Although this effect itself is not an advanced rhythmic ability such as dancing or singing, our results suggest that, to some extent, the biological foundation for spontaneous responses to auditory rhythms was already deeply rooted in the common ancestor of chimpanzees and humans, 6 million years ago. This also suggests the possibility of a common attentional mechanism, as proposed by the dynamic attending theory, underlying the effect of perceiving external rhythms on motor movement.

  15. Distractor Effect of Auditory Rhythms on Self-Paced Tapping in Chimpanzees and Humans.

    Science.gov (United States)

    Hattori, Yuko; Tomonaga, Masaki; Matsuzawa, Tetsuro

    2015-01-01

    Humans tend to spontaneously align their movements in response to visual (e.g., swinging pendulum) and auditory rhythms (e.g., hearing music while walking). Particularly in the case of the response to auditory rhythms, neuroscientific research has indicated that motor resources are also recruited while perceiving an auditory rhythm (or regular pulse), suggesting a tight link between the auditory and motor systems in the human brain. However, the evolutionary origin of spontaneous responses to auditory rhythms is unclear. Here, we report that chimpanzees and humans show a similar distractor effect in perceiving isochronous rhythms during rhythmic movement. We used isochronous auditory rhythms as distractor stimuli during self-paced alternate tapping of two keys of an electronic keyboard by humans and chimpanzees. When the tempo was similar to their spontaneous motor tempo, tapping onset was influenced by intermittent entrainment to auditory rhythms. Although this effect itself is not an advanced rhythmic ability such as dancing or singing, our results suggest that, to some extent, the biological foundation for spontaneous responses to auditory rhythms was already deeply rooted in the common ancestor of chimpanzees and humans, 6 million years ago. This also suggests the possibility of a common attentional mechanism, as proposed by the dynamic attending theory, underlying the effect of perceiving external rhythms on motor movement.

  16. The occurrence of Aeromonas in drinking water, tap water and the Porsuk River

    Directory of Open Access Journals (Sweden)

    Merih Kivanc

    2011-03-01

    Full Text Available The occurrence of Aeromonas spp. in the Porsuk River, public drinking water and tap water in the City of Eskisehir (Turkey was monitored. Fresh water samples were collected from several sampling sites during a period of one year. Total 102 typical colonies of Aeromonas spp. were submitted to biochemical tests for species differentiation and of 60 isolates were confirmed by biochemical tests. Further identifications of isolates were carried out first with the VITEK system (BioMe˜rieux and then selected isolates from different phenotypes (VITEK types were identified using the DuPont Qualicon RiboPrinter® system. Aeromonas spp. was detected only in the samples from the Porsuk River. According to the results obtained with the VITEK system, our isolates were 13% Aeromonas hydrophila, 37% Aeromonas caviae, 35% Pseudomonas putida, and 15% Pseudomonas acidovorans. In addition Pseudomonas sp., Pseudomonas maltophila, Aeromonas salmonicida, Aeromonas hydrophila, and Aeromonas media species were determined using the RiboPrinter® system. The samples taken from the Porsuk River were found to contain very diverse Aeromonas populations that can pose a risk for the residents of the city. On the other hand, drinking water and tap water of the City are free from Aeromonas pathogens and seem to be reliable water sources for the community.

  17. The Dynamic Photometric Stereo Method Using a Multi-Tap CMOS Image Sensor †

    Science.gov (United States)

    Yoda, Takuya; Nagahara, Hajime; Taniguchi, Rin-ichiro; Kagawa, Keiichiro; Yasutomi, Keita; Kawahito, Shoji

    2018-01-01

    The photometric stereo method enables estimation of surface normals from images that have been captured using different but known lighting directions. The classical photometric stereo method requires at least three images to determine the normals in a given scene. However, this method cannot be applied to dynamic scenes because it is assumed that the scene remains static while the required images are captured. In this work, we present a dynamic photometric stereo method for estimation of the surface normals in a dynamic scene. We use a multi-tap complementary metal-oxide-semiconductor (CMOS) image sensor to capture the input images required for the proposed photometric stereo method. This image sensor can divide the electrons from the photodiode from a single pixel into the different taps of the exposures and can thus capture multiple images under different lighting conditions with almost identical timing. We implemented a camera lighting system and created a software application to enable estimation of the normal map in real time. We also evaluated the accuracy of the estimated surface normals and demonstrated that our proposed method can estimate the surface normals of dynamic scenes. PMID:29510599

  18. The Dynamic Photometric Stereo Method Using a Multi-Tap CMOS Image Sensor.

    Science.gov (United States)

    Yoda, Takuya; Nagahara, Hajime; Taniguchi, Rin-Ichiro; Kagawa, Keiichiro; Yasutomi, Keita; Kawahito, Shoji

    2018-03-05

    The photometric stereo method enables estimation of surface normals from images that have been captured using different but known lighting directions. The classical photometric stereo method requires at least three images to determine the normals in a given scene. However, this method cannot be applied to dynamic scenes because it is assumed that the scene remains static while the required images are captured. In this work, we present a dynamic photometric stereo method for estimation of the surface normals in a dynamic scene. We use a multi-tap complementary metal-oxide-semiconductor (CMOS) image sensor to capture the input images required for the proposed photometric stereo method. This image sensor can divide the electrons from the photodiode from a single pixel into the different taps of the exposures and can thus capture multiple images under different lighting conditions with almost identical timing. We implemented a camera lighting system and created a software application to enable estimation of the normal map in real time. We also evaluated the accuracy of the estimated surface normals and demonstrated that our proposed method can estimate the surface normals of dynamic scenes.

  19. Evaluation of radon concentration in well and tap waters in Bursa (Turkey)

    International Nuclear Information System (INIS)

    Akar Tarim, U.; Gurler, O.; Akkaya, G.; Kilic, N.; Yalcin, S.; Kaynak, G.; Gundogdu, O.

    2012-01-01

    222 Rn measurements in water samples collected from 27 wells and 19 taps that were supplied from the investigated wells were conducted using the AlphaGUARD PQ 2000PRO radon gas analyser at sites across several geologic formations within the city of Bursa (Turkey). The measured radon concentrations ranged from 1.46 to 53.64 Bq l -1 for well water and from 0.91 to 12.58 Bq l -1 for tap water. Of the 27 sites sampled, only 7 had radon levels above the safe limit of 11.1 Bq l -1 recommended by the USEPA. In general, all determined concentrations were well below the 100 Bq l -1 revised reference level proposed by the European Union. These values of radon concentrations in water samples are compared with those reported from other countries. Doses resulting from the consumption of these waters were calculated. The minimum and the maximum annual mean effective doses due to 222 Rn intake through water consumption were 0.02 μSv a -1 and 1.11 μSv a -1 , respectively. (authors)

  20. How to Control Airline Routes from the Supply Side: The Case of TAP

    Science.gov (United States)

    Button, Kenneth; Costa, Alvaro; Reis, Vasco

    2005-01-01

    Competition in the European airline industry is currently fierce in the face of depressed demand conditions, and in the wake of privatizations and liberalization. The Portuguese flag carrier, TAP Air Portugal, operates within this environment. It is a medium sized carrier that was part of the defunct Qualiflyer Group alliance and has recently joined the Star Alliance. It controls more than 50% of the air market between Europe and Brazil and Europe and Angola. Nevertheless, it has been experiencing financial losses. One reason for this is that, following the reasoning of Ronald Coase (1946), it is difficult for any company with decreasing average costs to recover full costs in a highly competitive market. One way of approaching the problem is to establish quasi-monopoly power and airlines have done this through such things as frequent flyer programs and hub-and-spoke operations. Other airlines, notably charter carriers, have sought to adjust capacity and services to meet an anticipated cash flow. In practice, many have used a combination of measures with mixed success. This paper focuses on how TAP has responded to changing conditions by adjusting its supply-side activities in terms of restructuring its network to maximize potential revenues.

  1. Synthesis and Electroluminescent Properties of Bis(3H-1,2,3-triazolo-[4,5-b]pyridine-3-olzinc Zn(TAP2

    Directory of Open Access Journals (Sweden)

    Trinh Dac Hoanh

    2012-01-01

    Full Text Available A new light-emissive material, bis(3H-1,2,3-triazolo-[4,5-b]pyridine-3-olzinc (Zn(TAP2, has been synthesized and characterized by FT-NMR, FT-IR, UV-Vis, and elemental analysis. The photoluminescence (PL of Zn(TAP2 was measured from the DMF solution at 460 nm. The HOMO (6.5 eV and LUMO (2.8 eV energy levels of Zn(TAP2 were estimated from the measurement of cyclic voltammetry. The devices with structures of ITO/NPB/Zn(TAP2/LiF/Al and ITO/NPB/Zn(TAP2/Alq3/LiF/Al were constructed to investigate their electroluminescent (EL performance. Zn (TAP2 is supposed to be a good emitting material in the EL device.

  2. Biofilm formation in an experimental water distribution system: the contamination of non-touch sensor taps and the implication for healthcare.

    Science.gov (United States)

    Moore, Ginny; Stevenson, David; Thompson, Katy-Anne; Parks, Simon; Ngabo, Didier; Bennett, Allan M; Walker, Jimmy T

    2015-01-01

    Hospital tap water is a recognised source of Pseudomonas aeruginosa. U.K. guidance documents recommend measures to control/minimise the risk of P. aeruginosa in augmented care units but these are based on limited scientific evidence. An experimental water distribution system was designed to investigate colonisation of hospital tap components. P. aeruginosa was injected into 27 individual tap 'assemblies'. Taps were subsequently flushed twice daily and contamination levels monitored over two years. Tap assemblies were systematically dismantled and assessed microbiologically and the effect of removing potentially contaminated components was determined. P. aeruginosa was repeatedly recovered from the tap water at levels above the augmented care alert level. The organism was recovered from all dismantled solenoid valves with colonisation of the ethylene propylene diene monomer (EPDM) diaphragm confirmed by microscopy. Removing the solenoid valves reduced P. aeruginosa counts in the water to below detectable levels. This effect was immediate and sustained, implicating the solenoid diaphragm as the primary contamination source.

  3. A study of tapping by the unaffected finger of patients presenting with central and peripheral nerve damage.

    Science.gov (United States)

    Zhang, Lingli; Han, Xiuying; Li, Peihong; Liu, Yang; Zhu, Yulian; Zou, Jun; Yu, Zhusheng

    2015-01-01

    Whether the unaffected function of the hand of patients presenting with nerve injury is affected remains inconclusive. We aimed to evaluate whether there are differences in finger tapping following central or peripheral nerve injury compared with the unaffected hand and the ipsilateral hand of a healthy subject. Thirty right brain stroke patients with hemiplegia, 30 left arm peripheral nerve injury cases, and 60 healthy people were selected. We tested finger tapping of the right hands, and each subject performed the test twice. Finger tapping following peripheral nerve injury as compared with the unaffected hand and the dominant hand of a healthy person was markedly higher than was found for central nerve injury (P tapping of the male peripheral group's unaffected hand and the control group's dominant hand was significantly higher than the central group (P tapping of the female control group's dominant hand was significantly higher than the central group's unaffected hand (P < 0.01, P = 0.002), the peripheral group's unaffected hand (P < 0.05, P = 0.034). The unaffected function of the hand of patients with central and peripheral nerve injury was different as compared with the ipsilateral hand of healthy individuals. The rehabilitation therapist should intensify the practice of normal upper limb fine activities and coordination of the patient.

  4. Unidirectional adaptation in tempo in pairs of chimpanzees during simultaneous tapping movement: an examination under face-to-face setup.

    Science.gov (United States)

    Yu, Lira; Tomonaga, Masaki

    2016-04-01

    Many studies have reported a spontaneous nature to synchronized movement in humans and in non-human primates. However, it is not yet clear whether individuals mutually adapt their movement to each other or whether one individual significantly changes to synchronize with the other. In the current study, we examined a directionality of the tempo adaptation to understand an introductive process of interactional synchrony in pairs of chimpanzees. Four pairs, consisting of five female chimpanzees, produced a finger-tapping movement under a face-to-face experimental setup where both auditory and visual cues of the partner's movement were available. Two test conditions were prepared: alone and paired. An analysis of the tapping tempo depending on condition showed that only one chimpanzee in each pair significantly changed their tapping tempo in the direction of the partner's tapping tempo in the paired condition compared with the alone condition. The current study demonstrated that unidirectional adaptation in tempo occurs in pairs of chimpanzees when they simultaneously produce the tapping movement under auditory and visual interaction.

  5. Tap density equations of granular powders based on the rate process theory and the free volume concept.

    Science.gov (United States)

    Hao, Tian

    2015-02-28

    The tap density of a granular powder is often linked to the flowability via the Carr index that measures how tight a powder can be packed, under an assumption that more easily packed powders usually flow poorly. Understanding how particles are packed is important for revealing why a powder flows better than others. There are two types of empirical equations that were proposed to fit the experimental data of packing fractions vs. numbers of taps in the literature: the inverse logarithmic and the stretched exponential. Using the rate process theory and the free volume concept under the assumption that particles will obey similar thermodynamic laws during the tapping process if the "granular temperature" is defined in a different way, we obtain the tap density equations, and they are reducible to the two empirical equations currently widely used in literature. Our equations could potentially fit experimental data better with an additional adjustable parameter. The tapping amplitude and frequency, the weight of the granular materials, and the environmental temperature are grouped into this parameter that weighs the pace of the packing process. The current results, in conjunction with our previous findings, may imply that both "dry" (granular) and "wet" (colloidal and polymeric) particle systems are governed by the same physical mechanisms in term of the role of the free volume and how particles behave (a rate controlled process).

  6. Indoor Heating Drives Water Bacterial Growth and Community Metabolic Profile Changes in Building Tap Pipes during the Winter Season.

    Science.gov (United States)

    Zhang, Hai-Han; Chen, Sheng-Nan; Huang, Ting-Lin; Shang, Pan-Lu; Yang, Xiao; Ma, Wei-Xing

    2015-10-27

    The growth of the bacterial community harbored in indoor drinking water taps is regulated by external environmental factors, such as indoor temperature. However, the effect of indoor heating on bacterial regrowth associated with indoor drinking water taps is poorly understood. In the present work, flow cytometry and community-level sole-carbon-source utilization techniques were combined to explore the effects of indoor heating on water bacterial cell concentrations and community carbon metabolic profiles in building tap pipes during the winter season. The results showed that the temperature of water stagnated overnight ("before") in the indoor water pipes was 15-17 °C, and the water temperature decreased to 4-6 °C after flushing for 10 min ("flushed"). The highest bacterial cell number was observed in water stagnated overnight, and was 5-11 times higher than that of flushed water. Meanwhile, a significantly higher bacterial community metabolic activity (AWCD590nm) was also found in overnight stagnation water samples. The significant "flushed" and "taps" values indicated that the AWCD590nm, and bacterial cell number varied among the taps within the flushed group (p heating periods.

  7. A Study of Tapping by the Unaffected Finger of Patients Presenting with Central and Peripheral Nerve Damage

    Directory of Open Access Journals (Sweden)

    Lingli eZhang

    2015-05-01

    Full Text Available Aim: Whether the unaffected function of the hand of patients presenting with nerve injury is affected remains inconclusive. We aimed to evaluate whether there are differences in finger tapping following central or peripheral nerve injury compared with the unaffected hand and the ipsilateral hand of a healthy subject.Methods: 30 right brain stroke patients with hemiplegia, 30 left arm peripheral nerve injury cases and 60 healthy people were selected. We tested finger tapping of the right hands, and each subject performed the test twice.Results: Finger tapping following peripheral nerve injury as compared with the unaffected hand and the dominant hand of a healthy person was significantly higher than was found for central nerve injury (P<0.05. Finger tapping of the male peripheral group’s unaffected hand and the control group’s dominant hand was significantly higher than the central group (P<0.001. However, finger tapping of the female control group’s dominant hand was markedly higher than the central group’s unaffected hand (P<0.01, P=0.002, the peripheral group’s unaffected hand (P<0.05, P=0.034. Conclusion: The unaffected function of the hand of patients with central and peripheral nerve injury was different as compared with the ipsilateral hand of healthy individuals. The rehabilitation therapist should intensify the practice of normal upper limb fine activities and coordination of the patient.

  8. Increasing the frequency of hand washing by healthcare workers does not lead to commensurate reductions in staphylococcal infection in a hospital ward

    Directory of Open Access Journals (Sweden)

    Kerr Kevin G

    2008-09-01

    Full Text Available Abstract Background Hand hygiene is generally considered to be the most important measure that can be applied to prevent the spread of healthcare-associated infection (HAI. Continuous emphasis on this intervention has lead to the widespread opinion that HAI rates can be greatly reduced by increased hand hygiene compliance alone. However, this assumes that the effectiveness of hand hygiene is not constrained by other factors and that improved compliance in excess of a given level, in itself, will result in a commensurate reduction in the incidence of HAI. However, several researchers have found the law of diminishing returns to apply to hand hygiene, with the greatest benefits occurring in the first 20% or so of compliance, and others have demonstrated that poor cohorting of nursing staff profoundly influences the effectiveness of hand hygiene measures. Collectively, these findings raise intriguing questions about the extent to which increasing compliance alone can further reduce rates of HAI. Methods In order to investigate these issues further, we constructed a deterministic Ross-Macdonald model and applied it to a hypothetical general medical ward. In this model the transmission of staphylococcal infection was assumed to occur after contact with the transiently colonized hands of HCWs, who, in turn, acquire contamination only by touching colonized patients. The aim of the study was to evaluate the impact of imperfect hand cleansing on the transmission of staphylococcal infection and to identify, whether there is a limit, above which further hand hygiene compliance is unlikely to be of benefit. Results The model demonstrated that if transmission is solely via the hands of HCWs, it should, under most circumstances, be possible to prevent outbreaks of staphylococcal infection from occurring at a hand cleansing frequencies Conclusion Although our study confirmed hand hygiene to be an effective control measure, it demonstrated that the law of diminishing returns applies, with the greatest benefit derived from the first 20% or so of compliance. Indeed, our analysis suggests that there is little benefit to be accrued from very high levels of hand cleansing and that in most situations compliance > 40% should be enough to prevent outbreaks of staphylococcal infection occurring, if transmission is solely via the hands of HCWs. Furthermore we identified a non-linear relationship between hand cleansing efficacy and frequency, suggesting that it is important to maximise the efficacy of the hand cleansing process.

  9. Hand washing with soap and water together with behavioural recommendations prevents infections in common work environment: an open cluster-randomized trial.

    Science.gov (United States)

    Savolainen-Kopra, Carita; Haapakoski, Jaason; Peltola, Piia A; Ziegler, Thedi; Korpela, Terttu; Anttila, Pirjo; Amiryousefi, Ali; Huovinen, Pentti; Huvinen, Markku; Noronen, Heikki; Riikkala, Pia; Roivainen, Merja; Ruutu, Petri; Teirilä, Juha; Vartiainen, Erkki; Hovi, Tapani

    2012-01-16

    Hand hygiene is considered as an important means of infection control. We explored whether guided hand hygiene together with transmission-limiting behaviour reduces infection episodes and lost days of work in a common work environment in an open cluster-randomized 3-arm intervention trial. A total of 21 clusters (683 persons) were randomized to implement hand hygiene with soap and water (257 persons), with alcohol-based hand rub (202 persons), or to serve as a control (224 persons). Participants in both intervention arms also received standardized instructions on how to limit the transmission of infections. The intervention period (16 months) included the emergence of the 2009 influenza pandemic and the subsequent national hand hygiene campaign influencing also the control arm. In the total follow-up period there was a 6.7% reduction of infection episodes in the soap-and water arm (p = 0.04). Before the onset of the anti-pandemic campaign, a statistically significant (p = 0.002) difference in the mean occurrence of infection episodes was observed between the control (6.0 per year) and the soap-and-water arm (5.0 per year) but not between the control and the alcohol-rub arm (5.6 per year). Neither intervention had a decreasing effect on absence from work. We conclude that intensified hand hygiene using water and soap together with behavioural recommendations can reduce the occurrence of self-reported acute illnesses in common work environment. Surprisingly, the occurrence of reported sick leaves also increased in the soap-and water-arm. ClinicalTrials.gov: NCT00981877 The Finnish Work Environment Fund and the National Institute for Health and Welfare.

  10. Effect of water quality, sanitation, hand washing, and nutritional interventions on child development in rural Bangladesh (WASH Benefits Bangladesh): a cluster-randomised controlled trial.

    Science.gov (United States)

    Tofail, Fahmida; Fernald, Lia Ch; Das, Kishor K; Rahman, Mahbubur; Ahmed, Tahmeed; Jannat, Kaniz K; Unicomb, Leanne; Arnold, Benjamin F; Ashraf, Sania; Winch, Peter J; Kariger, Patricia; Stewart, Christine P; Colford, John M; Luby, Stephen P

    2018-04-01

    Poor nutrition and hygiene make children vulnerable to delays in growth and development. We aimed to assess the effects of water quality, sanitation, handwashing, and nutritional interventions individually or in combination on the cognitive, motor, and language development of children in rural Bangladesh. In this cluster-randomised controlled trial, we enrolled pregnant women in their first or second trimester from rural villages of Gazipur, Kishoreganj, Mymensingh, and Tangail districts of central Bangladesh, with an average of eight women per cluster. Groups of eight geographically adjacent clusters were block-randomised, using a random number generator, into six intervention groups (all of which received weekly visits from a community health promoter for the first 6 months and every 2 weeks for the next 18 months) and a double-sized control group (no intervention or health promoter visit). The six intervention groups were: chlorinated drinking water; improved sanitation; handwashing with soap; combined water, sanitation, and handwashing; improved nutrition through counselling and provision of lipid-based nutrient supplements; and combined water, sanitation, handwashing, and nutrition. Here, we report on the prespecified secondary child development outcomes: gross motor milestone achievement assessed with the WHO module at age 1 year, and communication, gross motor, personal social, and combined scores measured by the Extended Ages and Stages Questionnaire (EASQ) at age 2 years. Masking of participants was not possible. Analyses were by intention to treat. This trial is registered with ClinicalTrials.gov, number NCT01590095. Between May 31, 2012, and July 7, 2013, 5551 pregnant women residing in 720 clusters were enrolled. Index children of 928 (17%) enrolled women were lost to follow-up in year 1 and an additional 201 (3%) in year 2. 4757 children were assessed at 1 year and 4403 at 2 years. At year 1, compared with the control group, the combined water, sanitation, handwashing, and nutrition group had a higher rate of attaining the standing alone milestone (hazard ratio 1·19, 95% CI 1·01-1 ·40), and the nutrition group had a higher rate of attaining the walking alone milestone (1·32, 95% CI 1·07-1·62). The combined water, sanitation, handwashing, and nutrition group had a higher rate of attaining the walking alone milestone than those in the water, sanitation, and handwashing group (1·29, 1·01-1·65). At 2 years, we noted beneficial effects in the combined EASQ score in all intervention groups, with effect sizes smallest in the water treatment group (difference 0·15, 95% CI 0·04 to 0·26 vs control) and largest in the combined water, sanitation, handwashing, and nutrition treatment group (0·37, 0·27-0·46). Improvements in water quality, handwashing, sanitation, or nutrition supported by intensive interpersonal communication, when delivered either individually or in combination, contributed to improvements in child development. A crucial next step is to establish whether similar effects can be achieved with reduced intensity of promoter contacts that could be supported in large-scale interventions. Bill & Melinda Gates Foundation.

  11. Hand washing with soap and water together with behavioural recommendations prevents infections in common work environment: an open cluster-randomized trial

    Directory of Open Access Journals (Sweden)

    Savolainen-Kopra Carita

    2012-01-01

    Full Text Available Abstract Background Hand hygiene is considered as an important means of infection control. We explored whether guided hand hygiene together with transmission-limiting behaviour reduces infection episodes and lost days of work in a common work environment in an open cluster-randomized 3-arm intervention trial. Methods A total of 21 clusters (683 persons were randomized to implement hand hygiene with soap and water (257 persons, with alcohol-based hand rub (202 persons, or to serve as a control (224 persons. Participants in both intervention arms also received standardized instructions on how to limit the transmission of infections. The intervention period (16 months included the emergence of the 2009 influenza pandemic and the subsequent national hand hygiene campaign influencing also the control arm. Results In the total follow-up period there was a 6.7% reduction of infection episodes in the soap-and water arm (p = 0.04. Before the onset of the anti-pandemic campaign, a statistically significant (p = 0.002 difference in the mean occurrence of infection episodes was observed between the control (6.0 per year and the soap-and-water arm (5.0 per year but not between the control and the alcohol-rub arm (5.6 per year. Neither intervention had a decreasing effect on absence from work. Conclusions We conclude that intensified hand hygiene using water and soap together with behavioural recommendations can reduce the occurrence of self-reported acute illnesses in common work environment. Surprisingly, the occurrence of reported sick leaves also increased in the soap-and water-arm. Trial Registration ClinicalTrials.gov: NCT00981877 Source of funding The Finnish Work Environment Fund and the National Institute for Health and Welfare.

  12. The relationship of perceptions of tap water safety with intake of sugar-sweetened beverages and plain water among US adults.

    Science.gov (United States)

    Onufrak, Stephen J; Park, Sohyun; Sharkey, Joseph R; Sherry, Bettylou

    2014-01-01

    Research is limited on whether mistrust of tap water discourages plain water intake and leads to a greater intake of sugar-sweetened beverages (SSB). The objective of the present study was to examine demographic differences in perceptions of tap water safety and determine if these perceptions are associated with intake of SSB and plain water. The study examined perceptions of tap water safety and their cross-sectional association with intake of SSB and plain water. Racial/ethnic differences in the associations of tap water perceptions with SSB and plain water intake were also examined. Nationally weighted data from the 2010 HealthStyles Survey (n 4184). US adults aged ≥18 years. Overall, 13·0 % of participants disagreed that their local tap water was safe to drink and 26·4 % of participants agreed that bottled water was safer than tap water. Both mistrust of tap water safety and favouring bottled water differed by region, age, race/ethnicity, income and education. The associations of tap water mistrust with intake of SSB and plain water were modified by race/ethnicity (P beverages should recognize the potential impact of tap water perceptions on water and SSB intake among minority populations.

  13. Performance and touch characteristics of disabled and non-disabled participants during a reciprocal tapping task using touch screen technology.

    Science.gov (United States)

    Irwin, Curt B; Sesto, Mary E

    2012-11-01

    Touch screens are becoming more prevalent in everyday environments. Therefore, it is important that this technology is accessible to those with varying disabilities. The objective of the current study was to evaluate performance and touch characteristics (forces, impulses, and dwell times) of individuals with and without a movement disorder during a reciprocal tapping touch screen task. Thirty-seven participants with a motor control disability and 15 non-disabled participants participated. Outcome measures include number of correct taps, dwell time, exerted force, and impulse. Results indicate non-disabled participants had 1.8 more taps than participants with fine motor control disabilities and 2.8 times more than those with gross motor impairments (ptouch characteristics exist between those with and without motor control disabilities. Understanding how people (including those with disabilities) interact with touch screens may allow designers and engineers to ultimately improve usability of touch screen technology. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  14. Scaling law to determine peak forces in tapping-mode AFM experiments on finite elastic soft matter systems.

    Science.gov (United States)

    Guzman, Horacio V

    2017-01-01

    Analytical equations to estimate the peak force will facilitate the interpretation and the planning of amplitude-modulation force microscopy (tapping mode) experiments. A closed-form analytical equation to estimate the tip-sample peak forces while imaging soft materials in liquid environment and within an elastic deformation regime has been deduced. We have combined a multivariate regression method with input from the virial-dissipation equations and Tatara's bidimensional deformation contact mechanics model. The equation enables to estimate the peak force based on the tapping mode observables, probe characteristics and the material properties of the sample. The accuracy of the equation has been verified by comparing it to numerical simulations for the archetypical operating conditions to image soft matter with high spatial resolution in tapping-mode AFM.

  15. Analysis of step-up transformer tap change on the quantities at the point of connection to transmission grid

    Directory of Open Access Journals (Sweden)

    Đorđević Dragan

    2017-01-01

    Full Text Available The analysis of a step-up transformer tap change on the quantities at the point of connection to the transmission grid is presented in this paper. The point of connection of generator TENT A6 has been analyzed, and a detailed model of this generator is available in software package DIgSILENT Power Factory. The comparison between the effect of a step-up transformer tap change on the quantities at the point of connection during automatic and manual operation of voltage regulator has been conducted. In order to conduct the analysis of the manual operation of the voltage regulator, the comparison between the different methods of modeling of these modes has been performed. Several generator operating points, selected in order to represent the need for tap change, have been analyzed. Also, previously mentioned analyses have been performed taking into account the voltage-reactive stiffness at the point of connection.

  16. Neural correlates of cerebellar-mediated timing during finger tapping in children with fetal alcohol spectrum disorders.

    Science.gov (United States)

    du Plessis, Lindie; Jacobson, Sandra W; Molteno, Christopher D; Robertson, Frances C; Peterson, Bradley S; Jacobson, Joseph L; Meintjes, Ernesta M

    2015-01-01

    Classical eyeblink conditioning (EBC), an elemental form of learning, is among the most sensitive indicators of fetal alcohol spectrum disorders. The cerebellum plays a key role in maintaining timed movements with millisecond accuracy required for EBC. Functional MRI (fMRI) was used to identify cerebellar regions that mediate timing in healthy controls and the degree to which these areas are also recruited in children with prenatal alcohol exposure. fMRI data were acquired during an auditory rhythmic/non-rhythmic finger tapping task. We present results for 17 children with fetal alcohol syndrome (FAS) or partial FAS, 17 heavily exposed (HE) nonsyndromal children and 16 non- or minimally exposed controls. Controls showed greater cerebellar blood oxygen level dependent (BOLD) activation in right crus I, vermis IV-VI, and right lobule VI during rhythmic than non-rhythmic finger tapping. The alcohol-exposed children showed smaller activation increases during rhythmic tapping in right crus I than the control children and the most severely affected children with either FAS or PFAS showed smaller increases in vermis IV-V. Higher levels of maternal alcohol intake per occasion during pregnancy were associated with reduced activation increases during rhythmic tapping in all four regions associated with rhythmic tapping in controls. The four cerebellar areas activated by the controls more during rhythmic than non-rhythmic tapping have been implicated in the production of timed responses in several previous studies. These data provide evidence linking binge-like drinking during pregnancy to poorer function in cerebellar regions involved in timing and somatosensory processing needed for complex tasks requiring precise timing.

  17. Insights into SCP/TAPS proteins of liver flukes based on large-scale bioinformatic analyses of sequence datasets.

    Directory of Open Access Journals (Sweden)

    Cinzia Cantacessi

    Full Text Available BACKGROUND: SCP/TAPS proteins of parasitic helminths have been proposed to play key roles in fundamental biological processes linked to the invasion of and establishment in their mammalian host animals, such as the transition from free-living to parasitic stages and the modulation of host immune responses. Despite the evidence that SCP/TAPS proteins of parasitic nematodes are involved in host-parasite interactions, there is a paucity of information on this protein family for parasitic trematodes of socio-economic importance. METHODOLOGY/PRINCIPAL FINDINGS: We conducted the first large-scale study of SCP/TAPS proteins of a range of parasitic trematodes of both human and veterinary importance (including the liver flukes Clonorchis sinensis, Opisthorchis viverrini, Fasciola hepatica and F. gigantica as well as the blood flukes Schistosoma mansoni, S. japonicum and S. haematobium. We mined all current transcriptomic and/or genomic sequence datasets from public databases, predicted secondary structures of full-length protein sequences, undertook systematic phylogenetic analyses and investigated the differential transcription of SCP/TAPS genes in O. viverrini and F. hepatica, with an emphasis on those that are up-regulated in the developmental stages infecting the mammalian host. CONCLUSIONS: This work, which sheds new light on SCP/TAPS proteins, guides future structural and functional explorations of key SCP/TAPS molecules associated with diseases caused by flatworms. Future fundamental investigations of these molecules in parasites and the integration of structural and functional data could lead to new approaches for the control of parasitic diseases.

  18. Validation of the TAPS-1: A Four-Item Screening Tool to Identify Unhealthy Substance Use in Primary Care.

    Science.gov (United States)

    Gryczynski, Jan; McNeely, Jennifer; Wu, Li-Tzy; Subramaniam, Geetha A; Svikis, Dace S; Cathers, Lauretta A; Sharma, Gaurav; King, Jacqueline; Jelstrom, Eve; Nordeck, Courtney D; Sharma, Anjalee; Mitchell, Shannon G; O'Grady, Kevin E; Schwartz, Robert P

    2017-09-01

    The Tobacco, Alcohol, Prescription Medication, and Other Substance use (TAPS) tool is a combined two-part screening and brief assessment developed for adult primary care patients. The tool's first-stage screening component (TAPS-1) consists of four items asking about past 12-month use for four substance categories, with response options of never, less than monthly, monthly, weekly, and daily or almost daily. To validate the TAPS-1 in primary care patients. Participants completed the TAPS tool in self- and interviewer-administered formats, in random order. In this secondary analysis, the TAPS-1 was evaluated against DSM-5 substance use disorder (SUD) criteria to determine optimal cut-points for identifying unhealthy substance use at three severity levels (problem use, mild SUD, and moderate-to-severe SUD). Two thousand adult patients at five primary care sites. DSM-5 SUD criteria were determined via the modified Composite International Diagnostic Interview. Oral fluid was used as a biomarker of recent drug use. Optimal frequency-of-use cut-points on the self-administered TAPS-1 for identifying SUDs were ≥ monthly use for tobacco and alcohol (sensitivity = 0.92 and 0.71, specificity = 0.80 and 0.85, AUC = 0.86 and 0.78, respectively) and any reported use for illicit drugs and prescription medication misuse (sensitivity = 0.93 and 0.89, specificity = 0.85 and 0.91, AUC = 0.89 and 0.90, respectively). The performance of the interviewer-administered format was similar. When administered first, the self-administered format yielded higher disclosure rates for past 12-month alcohol use, illicit drug use, and prescription medication misuse. Frequency of use alone did not provide sufficient information to discriminate between gradations of substance use problem severity. Among those who denied drug use on the TAPS-1, less than 4% had a drug-positive biomarker. The TAPS-1 can identify unhealthy substance use in primary care patients with a high level of accuracy

  19. Optical UWB pulse generator using an N tap microwave photonic filter and phase inversion adaptable to different pulse modulation formats.

    Science.gov (United States)

    Bolea, Mario; Mora, José; Ortega, Beatriz; Capmany, José

    2009-03-30

    We propose theoretically and demonstrate experimentally an optical architecture for flexible Ultra-Wideband pulse generation. It is based on an N-tap reconfigurable microwave photonic filter fed by a laser array by using phase inversion in a Mach-Zehnder modulator. Since a large number of positive and negative coefficients can be easily implemented, UWB pulses fitted to the FCC mask requirements can be generated. As an example, a four tap pulse generator is experimentally demonstrated which complies with the FCC regulation. The proposed pulse generator allows different pulse modulation formats since the amplitude, polarity and time delay of generated pulse is controlled.

  20. The photon tagging facility for the Crystal-Barrel/TAPS experiment at ELSA; Die Photonenmarkierungsanlage fuer das Crystal-Barrel/TAPS-Experiment an ELSA

    Energy Technology Data Exchange (ETDEWEB)

    Fornet-Ponse, Kathrin

    2009-11-15

    With the CBELASA/TAPS experiment in the framework of the SFB/TR 16 measurements of single- and double-polarization observables in the photoporoduction were performed. The energy of the high-energetic, polarized photon beams required for this, is determined by means of a so-called tagging system. In the framework of this thesis such a tagging system was constructed. It allows the energy tagging of the photons in an energy range from 0.021.E{sub 0} to 0.871.E{sub 0} with a time resolution of {sigma}=0.240 ns and an energy resolution from 0.1%.E{sub 0} to 0.4%.E{sub 0}. The reached time resolution allows to use the tagging system as time reference for the remaining experimental components. For the calculation of cross sections the knowledge of the photon flux at the experimental target is necessary. Thereby the photon definition probability P{sub {gamma}} plays a central role, which indicates, with which probability for a signal from the tagging system the corresponding photon in the {gamma} beam at the production target is present. It could be found a prescription for the determination of P{sub {gamma}}, which yields at tagging rates from 1 MHz to 10 MHz consistent results. A relative systematic error for P{sub {gamma}} was determined. Furthermore the effects of collimation and divergence of the photon beam on the number of the really in the experiment available photons and by this on the maximally reachable P{sub {gamma}} were extensively studied and experimental observations explained. [German] Mit dem CBELSA/TAPS-Experiment werden im Rahmen des SFB/TR 16 Messungen von Einfach- und Doppelpolarisationsobservablen in der Photoproduktion durchgefuehrt. Die hochenergetischen, polarisierten Photonenstrahlen werden ueber den Bremsstrahlungsprozess erzeugt. Die Energie der Photonen bestimmt sich aus der Differenz zwischen der Elektronenergie vor (E{sub 0}) und nach (E{sub e{sup -}}) dem Bremsstrahlungsprozess. Dies erfordert den Nachweis der Sekundaerelektronen mit Hilfe